PATENT CLAIM ANALYSIS

Application Number: 15747850
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "254030"]

Abstract:
The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases, including infectious diseases; neoplasms; endocrine, nutritional and metabolic diseases; mental and behavioral disorders; neurological diseases; diseases of the eye and adnexa; cardiovascular diseases; respiratory diseases; digestive diseases; diseases of the skin and subcutaneous tissue; diseases of the musculoskeletal system and connective tissue; or congenital malformations, deformations and chromosomal abnormalities.

Claim (Index 5):
The 1,3,4-oxadiazole sulfamide derivative compound represented by formula I, stereoisomer thereof or pharmaceutically acceptable salt thereof according to  claim 1 , wherein the compound represented by formula I is selected from the group consisting of compounds described in the following table: Ex. Comp. Structure \u20021 11198   \u20022 11199   \u20023 11293   \u20024 11294   \u20025 11295   \u20026 11296   \u20027 11297   \u20028 11298   \u20029 11299   10 11300   11 11301   12 11302   13 11303   14 11304   15 11305   16 11306   17 11307   18 11308   19 11309   20 11310   21 11311   22 11312   23 11313   24 11314   25 11315   26 11316   27 11317   28 11318   29 11319   30 11320   31 11321   32 11322   33 11363   34 11379   35 11440   36 11498   37 11527   38 11528   39 11574   40 11575   41 11640   42 11641   43 11642   44 11643   45 11644   46 11651   47 11652   48 11653   49 11654   50 11659   51 11660   52 11661   53 11662   54 11670   55 11671   56 11672   57 11673   58 11674   59 11702   60 11704   61 11713   62 11714   63 11787   64 11788   65 11789   66 11823   67 11824   68 11825   69 11826   70 11827   71 11828   72 11829   73 11830   74 11831   75 11832   76 11833

Metadata:
- Claim Count in Document: 20.0
- Percentile: 86.0
- Lexical Diversity: 1.98734
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15747952', '15748081', '15763972', '11252232', '13522044']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.825340244644436
- 35 USC 102 Novelty (BERT): 0.5768295924750348
- Combined Prediction Score: 0.8004891794274959
- Mean Citation Score: 389.701144
- Max Citation Score: 467.68665
- Similarity Product: 413.7297919980346

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test