PATENT CLAIM ANALYSIS

Application Number: 16060294
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "210160"]

Abstract:
Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated to modulate the NMDA receptor.

Claim (Index 11):
A compound represented by Formula II: and pharmaceutically acceptable salts, stereoisomers and prodrugs thereof, wherein: R 1  and R 2  are each independently selected from the group consisting of hydrogen, halogen, hydroxyl, NR a R b , C 1-4  alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, and C 3-6 cycloalkoxy; wherein C 1-4  alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, and C 3-6 cycloalkoxy may be optionally substituted with one, two or three substituents each independently selected from halogen, hydroxyl, cyano, and NR a R b ; R 3  is selected from the group consisting of phenyl, naphthyl, heteroaryl, heterocyclyl and C 3-6 cycloalkyl; wherein R 3  may optionally be substituted with one, two or three substituents each independently selected from C 1-4 alkyl, halogen, hydroxyl, cyano, C 1-4 alkoxy, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, C 1-6 alkyl-S(O) 2 \u2014, C 1-6 alkylcarbonyl, R a R b N\u2014SO 2 \u2014, NR a R b , C(O)OH, C 1-4 alkoxycarbonyl, and NR a R b carbonyl; and wherein C 1-4 alkyl, C 1-4 alkoxy, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, C 1-6 alkyl-S(O) 2 \u2014, and C 1-6 alkylcarbonyl may be optionally substituted by one or more substituents each independently selected from halogen, hydroxyl, cyano, and NR a R b ; R 66  and R 67  are each independently selected from the group consisting of hydrogen, halogen, C 1-4 alkyl (optionally substituted by one, two, three substituents selected from halogen, hydroxyl, cyano and NR a R b ), and phenyl (optionally substituted by one, two or three halogens); and R a  and R b  are independently selected, for each occurrence, from the group consisting of hydrogen and C 1-3 alkyl; or R a  and R b , together with the nitrogen to which they are attached, form a 4-6 membered heterocyclic ring which may have an additional heteroatom selected from O, S, or N.

Metadata:
- Claim Count in Document: 54.0
- Percentile: 94.0
- Lexical Diversity: 1.46875
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16060056', '12118492', '14038324', '12598882', '11487884']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8341477014474843
- 35 USC 102 Novelty (BERT): 0.5154815615671737
- Combined Prediction Score: 0.8022810874594533
- Mean Citation Score: 289.071046
- Max Citation Score: 315.1641
- Similarity Product: 229.55906579124928

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test