PATENT CLAIM ANALYSIS

Application Number: 16017781
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "247000"]

Abstract:
Disclosed are methods for treating disorders associated with dopamine receptor activity. In some embodiments, the disclosed methods include assaying the nucleic acid from a subject for the genotype of the variable number tandem repeats (VNTR) polymorphism in the dopamine transporter DAT1/SLC6A3 gene, wherein when one or two alleles for 9 tandem repeats is detected a dopamine partial agonist is administered to the subject; and wherein when two alleles for 10 tandem repeats is detected a dopamine modulator is not administered to the subject. Also provided are methods for treating disorders associated with dopamine receptor activity that include genotyping a subject with respect to a COMT polymorphism, a DRD2 polymorphism, a 48-base-pair VNTR polymorphism in DRD4 exon 3, and/or a ANKK1 TaqA1 polymorphism, and methods for detecting susceptibility to dopamine modulator therapy for conditions associated with dopamine receptor activity.

Claim (Index 8):
The method of  claim 7 , wherein the one or more genotyping assays further comprise a genotyping assay that determines the subject's genome with respect to the rs4680 polymorphism in the COMT gene.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 94.0
- Lexical Diversity: 2.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13880694', '14796989', '10170356', '09632838', '13739970']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7980935465903679
- 35 USC 102 Novelty (BERT): 0.567046566973335
- Combined Prediction Score: 0.7749888486286646
- Mean Citation Score: 395.189422
- Max Citation Score: 471.44687000000016
- Similarity Product: 320.488249231844

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test