PATENT CLAIM ANALYSIS

Application Number: 15768656
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["424", "164100"]

Abstract:
The invention provides for an isolated antibody that specifically recognizes an epitope of the lipopolysaccharide (LPS) O3b-antigen structure of  Klebsiella pneumoniae , which is a O3b-epitope incorporated in O3b-antigen comprising the structure of Formula (I), including one or more O3b-antigen mannose homopolymer repeating units, wherein Formula (I) is: MeP→3)-α-D-Manp-(1→2)-α-D-Manp-(1→3)-α-D-Manp-(1→[3)-α-D-Manp-(1→2)-α-D-Manp-(1→3)-α-D-Manp-(1→] n  wherein MeP is methyl phosphate; and n is 0-50. The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody.

Claim (Index 33):
The antibody of  claim 31 , which is the 4D3-A4 antibody or which competitively binds to its specific epitope, wherein the 4D3-A4 antibody is characterized by any of\n a) the 6 CDR sequences which are CDR1, 2, 3, 4, 5, and 6 identified by SEQ ID 1, 2, 3, 4, 5, and 6, respectively, wherein numbering is according to Kabat; or CDR1, 2, 3, 4, 5, and 6 identified by SEQ ID 7, 8, 9, 10, 11, and 12, respectively, wherein numbering is according to IMGT; and/or b) the VH and VL sequences which are the VH sequence identified by SEQ ID 15 and the VL sequence identified by SEQ ID 16; and/or c) the HC and LC sequences which are the HC sequence identified by SEQ ID 13 and the LC sequence identified by SEQ ID 14.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.85938
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15842068', '15509041', '13981442', '14055222', '12522290']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6705125289954552
- 35 USC 102 Novelty (BERT): 0.5065309957663616
- Combined Prediction Score: 0.6541143756725458
- Mean Citation Score: 186.746604
- Max Citation Score: 197.52673
- Similarity Product: 124.5822027511978

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test