PATENT CLAIM ANALYSIS

Application Number: 16160006
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2020-01
Patent Classification: ["424", "093700"]

Abstract:
Bone marrow containers are described herein. Separation systems for separating activated immune cells from other components are described herein. Methods of activating an immune cell are described herein.

Claim (Index 11):
A method of activating immune cells of a subject, the method comprising:\n obtaining bone marrow of the subject, the bone marrow comprising immune cells; incubating the bone marrow with a non-ionic hydrophilic branched polysaccharide and a TLR2 ligand, wherein the non-ionic hydrophilic branched polysaccharide comprises poly(sucrose-co-epichlorhydrin),\n wherein the non-ionic hydrophilic branched polysaccharide is at a concentration, wherein, if the bone marrow is contacted with whole blood and centrifuged, said concentration is sufficient to permit fluid movement of whole blood through the non-ionic hydrophilic branched polysaccharide without separation of erythrocytes, \n wherein the non-ionic hydrophilic branched polysaccharide has a molecular weight greater than 20 kDa, and \n wherein the incubating is performed until the immune cells are activated; and \n administering the activated immune cells to the subject.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 97.0
- Lexical Diversity: 1.40909
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14383288', '11537200', '12994603', '10573944', '13827170']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6732525227362567
- 35 USC 102 Novelty (BERT): 0.4839389480037568
- Combined Prediction Score: 0.6543211652630068
- Mean Citation Score: 155.44167799999997
- Max Citation Score: 163.86627
- Similarity Product: 109.95260737266182

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test