PATENT CLAIM ANALYSIS

Application Number: 15741816
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "186100"]

Abstract:
The present application discloses stability-indicating potency assays for influenza vaccines.

Claim (Index 1):
A method comprising the steps of:\n a) providing a sample comprising immunogenic HA, inactive HA, or combination thereof; b) subjecting the sample to biological proteolysis, wherein the inactive HA is digested and the immunogenic HA remains undigested; c) separating the digested inactive HA from the undigested immunogenic HA in the sample; d) subjecting the undigested immunogenic HA to analytical proteolysis, so as to provide fragments of digested immunogenic HA; e) carrying out a liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS) in the presence of at least one labeled reference HA peptide, to quantify the amount of immunogenic HA in the sample.

Metadata:
- Claim Count in Document: 122.0
- Percentile: 86.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11119631', '12587136', '14619693', '14829158', '12704928']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7038901380347072
- 35 USC 102 Novelty (BERT): 0.5341122033340894
- Combined Prediction Score: 0.6869123445646454
- Mean Citation Score: 298.979428
- Max Citation Score: 352.89908
- Similarity Product: 273.7910501822567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test