PATENT CLAIM ANALYSIS

Application Number: 16075924
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-03
Patent Classification: ["514", "252180"]

Abstract:
The invention relates to inhibitors of dihydrofolate reductase and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as  T. gondii, T. cruzi, P. falciparum, T. brucei , or  L. major  infections, using the novel inhibitors of the invention.

Claim (Index 9):
The compound of one of  claims 1 - 8 , wherein R 10  is substituted with at least one substituent selected from alkyl, cycloalkyl, halogen (e.g., fluoro), hydroxyl, alkoxy, cycloalkyloxy, cycloalkylalkyl, cycloalkylalkoxy, phosphoryl, phosphate, phosphonate, phosphinate, amino, amidine, imine, cyano, azido, sulfhydryl, or alkylthio, heterocyclyl, aralkyl, or an aromatic or heteroaromatic moiety.

Metadata:
- Claim Count in Document: 60.0
- Percentile: 96.0
- Lexical Diversity: 1.57576
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12691607', '15038038', '14511847', '13991321', '13256071']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7850542834672793
- 35 USC 102 Novelty (BERT): 0.5024520174626494
- Combined Prediction Score: 0.7567940568668163
- Mean Citation Score: 257.437782
- Max Citation Score: 260.07645
- Similarity Product: 194.7486973704636

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test