PATENT CLAIM ANALYSIS

Application Number: 15746806
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-12
Patent Classification: ["514", "04400A"]

Abstract:
The present invention relates to the combination of a PARP inhibitor with a Dbait molecule for treating cancer.

Claim (Index 4):
The pharmaceutical composition according to  claim 1 , wherein the molecule of formula (I), (II) or (III) has one or several of the following features:\n n is an integer from 23 to 195 or from 27 to 95; and/or N is a deoxynucleotide selected from the group consisting of A (adenine), C (cytosine), T (thymine) and G (guanine) and selected so as to avoid occurrence of a CpG dinucleotide and to have less than 80% sequence identity to any gene in a human genome; and/or the linked L\u2032 is selected from the group consisting of hexaethyleneglycol, tetradeoxythymidylate (T4), 1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane and 2,19-bis(phosphor)-8-hydraza-1-hydroxy-4-oxa-9-oxo-nonadecane; and/or m is 1 and L is a carboxamido polyethylene glycol, more preferably carboxamido triethylene glycol or carboxamido tetraethylene glycol; and/or C is selected from the group consisting of a cholesterol, single or double chain fatty acids such as octadecyl, oleic acid, dioleoyl or stearic acid, or ligand (including peptide, protein, aptamer) which targets cell receptor such as folic acid, tocopherol, sugar such as galactose and mannose and their oligosaccharide, peptide such as RGD and bombesin, and protein such transferring and integrin, preferably is a cholesterol or a tocopherol, still more preferably a cholesterol.

Metadata:
- Claim Count in Document: 67.0
- Percentile: 86.0
- Lexical Diversity: 1.05556
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13703965', '14118583', '15632951', '15232844', '14923482']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8640022298161795
- 35 USC 102 Novelty (BERT): 0.5716312274262649
- Combined Prediction Score: 0.834765129577188
- Mean Citation Score: 480.07088600000014
- Max Citation Score: 505.55835
- Similarity Product: 377.2933058934152

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test