PATENT CLAIM ANALYSIS

Application Number: 16390989
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["436", "131000"]

Abstract:
Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.

Claim (Index 10):
A method for determining the amount of 25-hydroxyvitamin D 3  and 25-hydroxyvitamin D 2  in a sample in a single assay, said method comprising:\n (a) ionizing by atmospheric pressure chemical ionization (APCI) said 25-hydroxyvitamin D 3  and 25-hydroxyvitamin D 2  to generate protonated and dehydrated precursor ions specific for each of said 25-hydroxyvitamin D 3  and 25-hydroxyvitamin D 2 ; (b) generating one or more fragment ions of each of said precursor ions; and (c) detecting the amount of one or more of said ions generated in step (a) or (b) or both and relating the detected ions to the amount of 25-hydroxyvitamin D 3  and 25-hydroxyvitamin D 2  in said sample.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 100.0
- Lexical Diversity: 2.22857
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15848325', '13115916', '15388844', '13327650', '13871457']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7541779256578044
- 35 USC 102 Novelty (BERT): 0.5793172673763413
- Combined Prediction Score: 0.7366918598296581
- Mean Citation Score: 481.07674
- Max Citation Score: 483.87936
- Similarity Product: 468.16863945287713

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test