PATENT CLAIM ANALYSIS

Application Number: 15990135
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-05
Patent Classification: ["552", "549000"]

Abstract:
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.

Claim (Index 65):
A process for preparing a compound of formula 1: the process comprising contacting \u0394-9,11-ene compound 4: with an alkylhydroperoxide of the formula (R 3 )(R 4 )(R 5 )C\u2014O\u2014OH in the presence of a co-oxidant, wherein Pg is a hydroxyl protecting group, R is hydrogen, hydroxyl, or \u2014OPg, R 1  is the 17-side chain of a bile acid selected from the group consisting of cholic acid, deoxycholic acid, taurocholic acid, and glycocholic acid, wherein the carboxyl functionality of said side chain is optionally esterified with a C 1 -C 6  alkyl group, and R 2  is hydrogen, or R 1  and R 2  together with the carbon atom attached thereto form a keto or a keto protecting group, and each of R 3 , R 4  and R 5  is independently C 1 -C 3  alkyl.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.69048
- Patent Class: 552.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15603290', '14532940', '15618092', '13816470', '14831722']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6162663312857773
- 35 USC 102 Novelty (BERT): 0.6100154948441856
- Combined Prediction Score: 0.6156412476416182
- Mean Citation Score: 253.802078
- Max Citation Score: 368.1219
- Similarity Product: 277.05207979670763

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test