PATENT CLAIM ANALYSIS

Application Number: 16166689
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["424", "190100"]

Abstract:
The present invention includes compositions and methods of preparing flagellar-coiling protein 1 (Fcp1)-deficient  Leptospira  bacterium. In one aspect, the invention includes an isolated, flagellar-coiling protein 1 (Fcp1)-deficient  Leptospira  bacterium. Another aspect includes a composition comprising a flagellar-coiling protein 1 (Fcp1) deficient  Leptospira  bacterium. Yet another aspect includes a method of producing a motility-deficient  Leptospira  bacterium comprising inhibiting expression of a wild-type flagellar-coiling protein 1 (Fcp1) gene. Methods of stimulating an immune response and reducing or treating an infectious disease caused by one or more  Leptospira  bacteria in a subject in need thereof comprising administering a composition comprising an effective amount of flagellar-coiling protein 1 (Fcp1) deficient  Leptospira  bacteria to the subject are also included.

Claim (Index 25):
The method of  claim 24 , wherein the  Leptospira  bacteria is deficit in a wild-type protein selected from the group consisting of flbB, flbD, flgA, flgB, flgC, flgD, flgG, flgH, flgI, flgM, flhA, flhB, flhF, flhX, fliA, fliE, fliF, fliG, fliG1, fliG3, fliH, fliI, fliJ, fliL, fliM, fliN, fliO, flip, fliQ, fliR, motA, motA1, motB, motB, flgE, flgJ, flgK, flgL, flhO, fliD, fliK, fcp1, fcp2, flaA1, flaA2, flaB1, flaB2, flaB3, flaB4, fliS, and any combination thereof.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 97.0
- Lexical Diversity: 2.07812
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15124633', '13216214', '13078879', '13359354', '12728177']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7970002674502443
- 35 USC 102 Novelty (BERT): 0.5921509986493101
- Combined Prediction Score: 0.7765153405701509
- Mean Citation Score: 377.809246
- Max Citation Score: 706.5204
- Similarity Product: 411.931085119772

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test