PATENT CLAIM ANALYSIS

Application Number: 15969328
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["546", "192000"]

Abstract:
Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

Claim (Index 19):
A method for monitoring the response of a patient having a disease or condition characterized by amyloid deposit to a treatment, comprising\n (i) forming a detectable complex following the treatment by contacting an effective amount of a compound of the formula: or a salt or solvate thereof, or a pharmaceutical composition thereof, with a sample, a body part, or a body area of the patient; and (ii) detecting the formation of the detectable complex, wherein a decrease of detectable complex as compared to before the treatment indicates that the patient is responsive to the treatment.

Metadata:
- Claim Count in Document: 48.0
- Percentile: 93.0
- Lexical Diversity: 1.4878
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14915883', '14572465', '14670088', '14507509', '16066285']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7547307293311283
- 35 USC 102 Novelty (BERT): 0.5920791777820672
- Combined Prediction Score: 0.7384655741762223
- Mean Citation Score: 368.946308
- Max Citation Score: 654.9379
- Similarity Product: 398.00509182431097

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test