PATENT CLAIM ANALYSIS

Application Number: 15914566
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["435", "320100"]

Abstract:
An expression vector containing appropriate mitochondrion-targeting sequences (MTS) and appropriate 3′UTR sequences provides efficient and stable delivery of a mRNA encoding a protein (CDS) to the mitochondrion of a mammalian cell. The MTS and 3′UTR sequences guide the CDS mRNA from the nuclear compartment of the cell to mitochondrion-bound polysomes, where the CDS is translated. This provides an efficient translocation of a mature functional protein into the mitochondria. A method of targeting mRNA expressed in the nuclear compartment of a mammalian cell to the mitochondrion is also provided. The vector and methods can be used to treat defects in mitochondrial function.

Claim (Index 5):
The expression vector of  claim 1 , wherein said mammalian cell is a human cell.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 90.0
- Lexical Diversity: 1.81967
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11913618', '10687677', '12526878', '13860156', '12143886']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6367761872973272
- 35 USC 102 Novelty (BERT): 0.6678815294073924
- Combined Prediction Score: 0.6398867215083338
- Mean Citation Score: 459.9062980000001
- Max Citation Score: 832.8029
- Similarity Product: 608.4325943104744

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test