PATENT CLAIM ANALYSIS

Application Number: 16372977
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-07
Patent Classification: ["514", "226500"]

Abstract:
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of conditions such as pain.

Claim (Index 1):
A method of improving oral bioavailability of meloxicam in a human being, comprising orally administering a solid dosage form comprising both a bicarbonate and meloxicam to the human being, wherein the solid dosage form contains 400 mg to 900 mg of the bicarbonate, wherein the oral bioavailability of meloxicam for the solid dosage form in the human being is improved as compared with a first reference dosage form that: 1) contains the same amount of meloxicam; 2) does not contain the bicarbonate; and 3) does not contain a carbonate, or a second reference dosage form that: a) contains the same amount of meloxicam; b) does not contain the bicarbonate; and c) contains an amount of potassium carbonate that achieves about the same pH as the bicarbonate; wherein the solid dosage form has been shown to have a median C max  that is about 1800 ng/mL to about 3000 ng/mL in fasted human subjects.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 100.0
- Lexical Diversity: 1.35135
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15988104', '16006692', '16372958', '15984055', '16000701']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7642073697554638
- 35 USC 102 Novelty (BERT): 0.5434754006460812
- Combined Prediction Score: 0.7421341728445254
- Mean Citation Score: 362.9238
- Max Citation Score: 378.7857
- Similarity Product: 376.0245984452784

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test