PATENT CLAIM ANALYSIS

Application Number: 15992287
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "282000"]

Abstract:
The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.

Claim (Index 16):
An oxycodone prodrug of the following formula where the prodrug moiety X is attached covalently to the oxycodone molecule via the 6 position ketone enolate oxygen as the enolate ester, and a prodrug moiety Y is attached covalently to the oxycodone molecule via the 14 position hydroxyl oxygen as the alcohol ester, or a pharmaceutically acceptable salt thereof, wherein X and Y are prodrug moiety ligands independently selected from the group consisting of monomeric alpha-hydroxy carboxylic acids, homo-oligomers of alpha-hydroxy carboxylic acid, hetero oligomers of alpha-hydroxy carboxylic acids with other alpha-hydroxy carboxylic acids, hetero oligomers of alpha-hydroxy carboxylic acids with amino acids, hetero oligomers of alpha-hydroxy carboxylic acids with dicarboxylic acids, hetero oligomers alpha-hydroxy carboxylic acids with fatty acids, fatty acids, and other GRAS-based reagents.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 93.0
- Lexical Diversity: 1.36957
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15472758', '14953392', '14956143', '10800898', '11635788']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8416034101471447
- 35 USC 102 Novelty (BERT): 0.5507346061067095
- Combined Prediction Score: 0.8125165297431012
- Mean Citation Score: 336.180702
- Max Citation Score: 418.85843
- Similarity Product: 352.3048618866408

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test