PATENT CLAIM ANALYSIS

Application Number: 15877336
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["435", "006110"]

Abstract:
The invention relates to methods of analysing a sample from a subject having or suspected of having Crohn's disease for the abundance of the subject's nucleic acid (e.g., DNA) in the sample. The invention also relates to methods for measuring abundance of nucleic acid (e.g., DNA) in stool from a human subject having or suspected of having Crohn's Disease (CD). In various embodiments, an in vitro method includes analysing the relative abundance of the host (human) DNA in said sample of stool or nucleic acid extracted or isolated from a stool sample from the host (human); determining the relative abundance of the host (human's) DNA in the sample; and associating the abundance of the host (human) DNA with the host (human) providing the stool sample, or the host (human) providing the stool sample from which the nucleic acid was extracted.

Claim (Index 37):
The method of  claim 32 , comprising the steps of:\n a) Obtaining a stool sample from said subject, b) Determining the relative abundance of host DNA in said sample, c) Determining the calprotectin gene level, in said sample or in another biological sample from said subject, and d) Diagnosing that said subject suffers from Crohn Disease, if said relative abundance is higher than a first reference value, and if said calprotectin gene level is higher than a second reference value.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 3.10909
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15011314', '15324032', '15035004', '14954496', '13469999']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5144288593368226
- 35 USC 102 Novelty (BERT): 0.5990735238812419
- Combined Prediction Score: 0.5228933257912646
- Mean Citation Score: 304.459766
- Max Citation Score: 550.8437
- Similarity Product: 437.18371903206713

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test