PATENT CLAIM ANALYSIS

Application Number: 16122862
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-05
Patent Classification: ["514", "300000"]

Abstract:
This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Claim (Index 56):
The method of  claim 55 , wherein said condition is hypergonadism, hypersexuality, sexual dysfunction, gynecomastia, precocious puberty in a male, alterations in cognition and mood, depression, hair loss, hyperandrogenic dermatological disorders, precancerous lesions of the prostate, benign prostate hyperplasia, prostate cancer and/or other androgen-dependent cancers.

Metadata:
- Claim Count in Document: 122.0
- Percentile: 97.0
- Lexical Diversity: 1.63333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15331777', '15135334', '15222734', '15981636', '15331751']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9038637916138628
- 35 USC 102 Novelty (BERT): 0.6862850851655489
- Combined Prediction Score: 0.8821059209690314
- Mean Citation Score: 873.4523800000003
- Max Citation Score: 923.45636
- Similarity Product: 670.2233042026616

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test