PATENT CLAIM ANALYSIS

Application Number: 15862139
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["436", "547000"]

Abstract:
The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.

Claim (Index 1):
A method of providing a prognosis for an individual that has NMO or a NMO-associated disease, comprising:\n providing a biological sample from the individual; and determining, in vitro, whether or not the biological sample reduces cell surface expression of EAAT2 or reduces uptake of extracellular glutamate compared to a biological sample from an individual that does not have NMO or a NMO-associated disease, wherein a reduction in cell surface expression of EAAT2 or a reduction in uptake of extracellular glutamate correlates with a prognosis of the individual.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.38889
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12573942', '14113061', '14539405', '11457685', '10723180']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6323395392115572
- 35 USC 102 Novelty (BERT): 0.5125649989584427
- Combined Prediction Score: 0.6203620851862457
- Mean Citation Score: 181.575178
- Max Citation Score: 315.84924
- Similarity Product: 188.1661976408816

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test