PATENT CLAIM ANALYSIS

Application Number: 16185437
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["514", "224200"]

Abstract:
The present invention provides a compound represented by the formula (I) wherein X is a hydrogen atom or a fluorine atom; R is a hydrogen atom or alkyl; R 1  is (1) cyclopropyl optionally substituted by 1 to 3 halogen atoms or (2) phenyl optionally substituted by 1 to 3 halogen atoms; R 2  is alkyl, alkoxy, haloalkoxy, a halogen atom, cyano, etc.; and R 3  is 7-oxo-7,8-dihydro-1,8-naphthyridinyl, 3-pyridyl, etc., or a salt thereof. The compound of the present invention has excellent, antimicrobial activity against  Clostridium difficile  and is useful for the prevention or treatment of intestinal infection such as  Clostridium difficile -associated diarrhea.

Claim (Index 14):
The compound of  claim 1 , wherein R 3  is a group of the formula wherein\n R 18a  is alkyl, and \n R 19a  is (a) a halogen atom,\n (b) cyano, \n (c) alkyl optionally substituted by 1 to 3 substituents selected from the group consisting of \n \n (i) a halogen atom, \n (ii) cyano, \n (iii) hydroxy, \n (iv) amino, \n (v) alkylamino, \n (vi) dialkylamino, and \n (vii) a cyclic amino group optionally substituted by alkyl,\n (d) alkoxy, \n (e) amino optionally substituted by 1 or 2 substituents selected from the group consisting of \n \n (i) alkylcarbonyl optionally substituted by a cyclic amino group, \n (ii) alkylsulfonyl, \n (iii) carbamoyl, and \n (iv) alkyl or cycloalkyl,\n (f) carboxy, \n (g) alkoxycarbonyl, \n (h) carbamoyl optionally substituted by alkyl optionally substituted by amino, alkylamino, dialkylamino or alkoxycarbonylamino, \n (i) formyl, \n (j) a 5- to 10-membered aromatic heterocyclic group optionally substituted by alkyl, \n (k) \u2014CH\u2550N\u2014OR 21  wherein R 21  is a hydrogen atom or alkyl optionally substituted by alkylamino or dialkylamino, or \n (l) nitro, \n \n or a salt thereof.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 98.0
- Lexical Diversity: 2.0
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14193656', '14692200', '15440548', '13262888', '10481367']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8152771968101814
- 35 USC 102 Novelty (BERT): 0.601274608299688
- Combined Prediction Score: 0.7938769379591321
- Mean Citation Score: 418.661232
- Max Citation Score: 501.5164
- Similarity Product: 493.2452374723195

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test