PATENT CLAIM ANALYSIS

Application Number: 15875125
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "134100"]

Abstract:
Provided are recombinant and chemically-conjugated antibodies and fragments thereof modified with one or more poly-aspartate (poly-D) peptides (e.g., a D10 sequence) to improve localization of the antibodies or fragments to bone. Methods of making and using of these antibodies and fragments also are disclosed.

Claim (Index 21):
The method of  claim 20 , further comprising detecting at least one of (1) a reduction in TGF\u03b2 levels, (2) a reduction in TGF\u03b2 activity, (3) a reduction in bone loss, (4) a reduction in rate of bone loss, (5) an increase in bone density, (6) an increase in bone strength, and (7) a reduction in IL-11 levels.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 86.0
- Lexical Diversity: 1.41667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15289032', '14716377', '14231933', '15517867', '15038202']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.702604382373544
- 35 USC 102 Novelty (BERT): 0.5383845328567644
- Combined Prediction Score: 0.6861823974218659
- Mean Citation Score: 331.820784
- Max Citation Score: 354.783
- Similarity Product: 172.1690227539539

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test