PATENT CLAIM ANALYSIS

Application Number: 16257987
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-08
Patent Classification: ["546", "112000"]

Abstract:
Provided is a method for preparing a tropane derivative, maraviroc, including reacting a compound of formula (II) with a compound of formula (I), wherein the compound of formula (II) is prepared by the steps of acetylation of a compound of formula (III), activation and substitution of a compound of formula (IV) by a chlorination agent, cyclization of a compound of formula (V), and debenzylation of a compound of formula (VI) by hydrogenation. Hence, the present disclosure provides a method for preparing maraviroc with good yield and simple operation.

Claim (Index 1):
A method for preparation of maraviroc, comprising\n reacting an intermediate compound represented by formula (IV) below, with a chlorination agent to obtain an intermediate compound represented by formula (V) below, and\n cyclizing the intermediate compound represented by formula (V) to obtain an intermediate compound represented by formula (VI) below,

Metadata:
- Claim Count in Document: 17.0
- Percentile: 99.0
- Lexical Diversity: 2.3617
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16089486', '13263397', '11024029', '13697806', '16066971']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7510959803137339
- 35 USC 102 Novelty (BERT): 0.4824480009991109
- Combined Prediction Score: 0.7242311823822716
- Mean Citation Score: 192.124958
- Max Citation Score: 202.75203
- Similarity Product: 147.6266658863997

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test