PATENT CLAIM ANALYSIS

Application Number: 16033016
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "006000"]

Abstract:
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.

Claim (Index 19):
The method of  claim 3 , wherein the targeter-RNA and the activator-RNA are not covalently linked by intervening nucleotides.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 95.0
- Lexical Diversity: 2.25424
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16033002', '16033005', '15803424', '14685504', '15138604']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5024957740883771
- 35 USC 102 Novelty (BERT): 0.6682369775810129
- Combined Prediction Score: 0.5190698944376407
- Mean Citation Score: 759.544016
- Max Citation Score: 767.0532
- Similarity Product: 645.2741337424277

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test