PATENT CLAIM ANALYSIS

Application Number: 16207854
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["544", "006000"]

Abstract:
The invention relates to 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

Claim (Index 25):
The compound according to  claim 1 , which has a structure according to general formula (XI) wherein R 2  means \u2014H or \u2014CH 3 ; R 3  means -phenyl or -3-fluorophenyl; R H  means \u2014CN; \u2014C 1 -C 4 -alkyl; \u2014CF 3 ; \u2014C 1 -C 4 -alkyl-C(\u2550O)NH 2 ; \u2014C 1 -C 4 -alkyl-S(\u2550O) 2 \u2014C 1 -C 4 -alkyl; \u2014C(\u2550O)\u2014C 1 -C 4 -alkyl; \u2014C(\u2550O)OH; \u2014C(\u2550O)O\u2014C 1 -C 4 -alkyl; \u2014C(\u2550O)NH 2 ; \u2014C(\u2550O)NHC 1 -C 4 -alkyl; \u2014C(\u2550O)N(C 1 -C 4 -alkyl) 2 ; \u2014C(\u2550O)NH(C 1 -C 4 -alkyl-OH); \u2014C(\u2550O)N(C 1 -C 4 -alkyl)(C 1 -C 4 -alkyl-OH); \u2014C(\u2550O)NH\u2014(CH 2 CH 2 O) 1-30 \u2014CH 3 ; -3-12-membered cycloalkyl, saturated or unsaturated, unsubstituted, mono- or polysubstituted; wherein said 3-12-membered cycloalkyl is optionally connected through \u2014CH 2 \u2014, \u2014NH\u2014, \u2014NCH 3 \u2014, \u2014NH\u2014(CH 2 ) 1-3 \u2014, \u2014NCH 3 (CH 2 ) 1-3 \u2014, \u2014(C\u2550O)\u2014, \u2014NHC(\u2550O)\u2014, \u2014NCH 3 C(\u2550O)\u2014, \u2014C(\u2550O)NH\u2014(CH 2 ) 1-3 \u2014, \u2014C(\u2550O)NCH 3 \u2014(CH 2 ) 1-3 \u2014; or -3-12-membered heterocycloalkyl, saturated or unsaturated, unsubstituted, mono- or polysubstituted; 6-14-membered aryl, unsubstituted, mono- or polysubstituted; wherein said 3-12-membered heterocycloalkyl is optionally connected through \u2014CH 2 \u2014, \u2014NH\u2014, \u2014NCH 3 \u2014, \u2014NH\u2014(CH 2 ) 1-3 \u2014, \u2014NCH 3 (CH 2 ) 1-3 \u2014, \u2014(C\u2550O)\u2014, \u2014NHC(\u2550O)\u2014, \u2014NCH 3 C(\u2550O)\u2014, \u2014C(\u2550O)NH\u2014(CH 2 ) 1-3 \u2014, \u2014C(\u2550O)NCH 3 \u2014(CH 2 ) 1-3 \u2014; R G  means \u2014CF 3 , \u2014S(\u2550O) 2 CH 3 ; \u2014NH 2 ; \u2014NHC 1 -C 4 -alkyl; \u2014N(C 1 -C 4 -alkyl) 2 ; \u2014NHC 1 -C 4 -alkyl-OH; \u2014NCH 3 C 1 -C 4 -alkyl-OH; \u2014NH\u2014C 1 -C 4 -alkyl-C(\u2550O)NH 2 ; \u2014NCH 3 \u2014C 1 -C 4 -alkyl-C(\u2550O)NH 2 ; \u2014NHC(\u2550O)\u2014C 1 -C 4 -alkyl; \u2014NCH 3 C(\u2550O)\u2014C 1 -C 4 -alkyl; -3-12-membered cycloalkyl, saturated or unsaturated, unsubstituted, mono- or polysubstituted; wherein said 3-12-membered cycloalkyl is optionally connected through \u2014CH 2 \u2014, \u2014NH\u2014, \u2014NCH 3 \u2014, \u2014NH\u2014(CH 2 ) 1-3 \u2014, \u2014NCH 3 (CH 2 ) 1-3 \u2014, \u2014(C\u2550O)\u2014, \u2014NHC(\u2550O)\u2014, \u2014NCH 3 C(\u2550O)\u2014, \u2014C(\u2550O)NH\u2014(CH 2 ) 1-3 \u2014, \u2014C(\u2550O)NCH 3 \u2014(CH 2 ) 1-3 \u2014; or -3-12-membered heterocycloalkyl, saturated or unsaturated, unsubstituted, mono- or polysubstituted; 6-14-membered aryl, unsubstituted, mono- or polysubstituted; wherein said 3-12-membered heterocycloalkyl is optionally connected through \u2014CH 2 \u2014, \u2014NH\u2014, \u2014NCH 3 \u2014, \u2014NH\u2014(CH 2 ) 1-3 \u2014, \u2014NCH 3 (CH 2 ) 1-3 \u2014, \u2014(C\u2550O)\u2014, \u2014NHC(\u2550O)\u2014, \u2014NCH 3 C(\u2550O)\u2014, \u2014C(\u2550O)NH\u2014(CH 2 ) 1-3 \u2014, \u2014C(\u2550O)NCH 3 \u2014(CH 2 ) 1-3 \u2014; or a physiologically acceptable salt thereof.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 98.0
- Lexical Diversity: 1.17857
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15125615', '12604691', '12699451', '15326138', '12700857']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8482187732959457
- 35 USC 102 Novelty (BERT): 0.5475490965127962
- Combined Prediction Score: 0.8181518056176308
- Mean Citation Score: 423.427142
- Max Citation Score: 437.00952
- Similarity Product: 301.0482497039223

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test