PATENT CLAIM ANALYSIS

Application Number: 15748284
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "133100"]

Abstract:
The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.

Claim (Index 167):
A method of treating a subject comprising, administering a stem cell mobilizing agent to the subject, harvesting hematopoietic stem cells from the subject, enriching the harvested stem cells for CCR2 positive (CCR2+) , CD34 positive (CD34+), or lineage negative (lin\u2212) cells, optionally depleting the harvested stem cells or CCR2\u2212 cells, administering to the subject the enriched harvested stem cells, and administering to the subject an immune checkpoint inhibitor.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 86.0
- Lexical Diversity: 1.19048
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14021353', '15170284', '14158531', '16068816', '15024396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7244433846503161
- 35 USC 102 Novelty (BERT): 0.5364525182697686
- Combined Prediction Score: 0.7056442980122614
- Mean Citation Score: 364.48628
- Max Citation Score: 390.14835
- Similarity Product: 245.5381225407779

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test