PATENT CLAIM ANALYSIS

Application Number: 16089235
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["514", "167000"]

Abstract:
Methods for treating vitamin D insufficiency and secondary hyperparathyroidism in patients having CKD comprising administering repeat doses of 25-hydroxyvitamin D are disclosed. The methods comprise administering 25-hydroxyvitamin D in an amount effective to safely raise the patient's serum 25-hydroxyvitamin D level to greater than 90 ng/ml and/or to control the patient's serum ratio of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D to less than 20.

Claim (Index 17):
A method of administering an extended release dosage form of 25-hydroxyvitamin D comprising about 30 mcg 25-hydroxyvitamin D 3 , optionally including a waxy controlled release agent, an emulsifier, an absorption enhancer, an oily vehicle, and a stabilizing agent; to a patient in need thereof, optionally having CKD Stage 3 or Stage 4, comprising administering repeat doses of the extended release oral dosage form to the subject effective to achieve one or more of the following: (1) an increase in mean serum 25-hydroxyvitamin D of about 1 ng/mL/week to about 7 ng/mL/week; (2) an increase in mean serum 1,25-dihydroxyvitamin D of about 1 to about 10 pg/mL/week; (3) a mean steady state serum 25-hydroxyvitamin D level of about 50 ng/mL to about 55 ng/mL.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 97.0
- Lexical Diversity: 1.45652
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15231357', '15358065', '12597224', '13244945', '15990354']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.81716164755367
- 35 USC 102 Novelty (BERT): 0.6173404197676798
- Combined Prediction Score: 0.797179524775071
- Mean Citation Score: 517.0578820000002
- Max Citation Score: 529.7744
- Similarity Product: 408.1901354320526

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test