PATENT CLAIM ANALYSIS

Application Number: 15979041
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "402000"]

Abstract:
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.

Claim (Index 32):
The method of  claim 31  wherein the toxicity management is a method of toxicity management selected from the group consisting of:\n (a) the use of colchicine or an analog thereof; \n (b) the use of a uricosuric; \n (c) the use of uricase; \n (d) the non-oral use of nicotinamide; \n (e) the use of a sustained-release form of nicotinamide; \n (f) the use of an inhibitor of poly-ADP ribose polymerase; \n (g) the use of caffeine; \n (h) the use of leucovorin rescue; \n (i) the use of sustained-release allopurinol; \n (j) the non-oral use of allopurinol; \n (k) the administration of bone marrow transplant stimulants, blood, platelet infusions, Neupogen, G-CSF; or GM-CSF; \n (l) pain management; \n (m) infection control; and \n (n) administration of anti-inflammatories; \n (o) administration of fluids; \n (p) administration of corticosteroids; \n (q) administration of insulin control medications; \n (r) administration of antipyretics; \n (s) administration of anti-nausea treatments; \n (t) administration of anti-diarrhea treatment; \n (u) administration of antihistamines as pre-treatment to prevent anaphylaxis; \n (v) administration of agents for reduction of gastric toxicity; \n (w) administration of steroids as pre-treatment to prevent anaphylaxis; \n (x) administration of sympathetomimetics as pre-treatment to prevent anaphylaxis; and \n (y) administration of an agent to control or prevent chemotherapy-induced thrombocytopenia.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 1.31579
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14907728', '14907729', '13817096', '14753911', '14245738']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7891466208043346
- 35 USC 102 Novelty (BERT): 0.5312817796874986
- Combined Prediction Score: 0.763360136692651
- Mean Citation Score: 267.787678
- Max Citation Score: 348.62634
- Similarity Product: 298.0921927083421

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test