PATENT CLAIM ANALYSIS

Application Number: 16205205
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-04
Patent Classification: ["424", "191100"]

Abstract:
Disclosed herein are non-myeloablative antibody-toxin conjugates and compositions that target cell surface markers, such as the CD34, CD45 or CD117 receptors, and related methods of their use to effectively conditioning a subject's tissues (e.g., bone marrow tissue) prior to engraftment or transplant. The compositions and methods disclosed herein may be used to condition a subject's tissues in advance of, for example, hematopoietic stem cell transplant and advantageously such compositions and methods do not cause the toxicities that are commonly associated with traditional conditioning methods.

Claim (Index 2):
The method of  claim 1 , where the toxin is an amatoxin.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 98.0
- Lexical Diversity: 1.47692
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15148837', '15504264', '15211679', '14800474', '14799328']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7250588989301052
- 35 USC 102 Novelty (BERT): 0.6443741681449805
- Combined Prediction Score: 0.7169904258515927
- Mean Citation Score: 398.897926
- Max Citation Score: 704.1681
- Similarity Product: 536.4422616067528

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test