PATENT CLAIM ANALYSIS

Application Number: 15752900
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "449000"]

Abstract:
The present application is directed to transdermal formulations for the delivery of berberine compounds to a subject for the treatment of berberine-responsive diseases. In particular, the transdermal formulation comprises: (a) an aqueous phase comprising water and at least one water soluble emulsion stabilizer; (b) an oil phase comprising at least one emulsifier, at least one oil soluble emulsion stabilizer, at least one emollient comprising at least one flavonoid and at least one other emollient; wherein the oil and aqueous phases form an emulsion; (c) an external phase comprising at least one flavonoid containing-extract, at least one phospholipid-complexed flavonoid and at least one source of berberine or analog or derivative thereof; and optionally (d) at least one preservative phase.

Claim (Index 4):
The transdermal formulation of  claim 1 , wherein the source of berberine or analog thereof is selected from one or more of barberry extract, meadow rue, celandine,  Berberis aquifolium, Berberis vulgaris, Hydrastis Canadensis, Xanthorhiza simplicissima, Phellodendron amurense californica  and  Mahonia aquifolium.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 88.0
- Lexical Diversity: 2.20968
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15681950', '14576476', '15022951', '12258341', '14857772']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7065637373394917
- 35 USC 102 Novelty (BERT): 0.5075560400370951
- Combined Prediction Score: 0.686662967609252
- Mean Citation Score: 204.80555400000003
- Max Citation Score: 206.40686
- Similarity Product: 120.36102385889052

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test