PATENT CLAIM ANALYSIS

Application Number: 16115973
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-01
Patent Classification: ["424", "450000"]

Abstract:
A process for treating tumors by administering a mixture of cancer fighting drugs incorporated into a stabilized liposomal formulation. Each cancer drug is selected to target a different phase of the cell-cycle of the cancer cell thus expanding the number of cancer cells that can be killed at one time without compromising the safety of the patient. The stabilized multi-drug liposomes are designed to extravasate thru “leaky” blood capillaries supplying the tumor and enter the tumor tissue where they will accumulate over time and ultimately release the mixture of cancer drugs to kill surrounding tumor cells. The multi-drug liposomes are likewise unable to extravasate thru normal blood capillaries and will thus be less toxic to normal tissues.

Claim (Index 14):
A method for forming a pharmaceutical composition for targeting tumor cells based upon their proliferative capacity, the method comprising the steps of:\n selecting a first cytotoxic drug based upon that first cytotoxic drug selectively targeting a first phase in the cell-cycle of tumor cells; selecting a second cytotoxic drug based upon that second cytotoxic drug selectively targeting a second phase in the cell-cycle of tumor cells, the second phase in the cell-cycle of tumor cells being different from the first phase in the cell-cycle of tumor cells; and enclosing the first and second cytotoxic drugs within a liposome; wherein the first cytotoxic drug is water soluble and enclosed within an aqueous interior of the liposome; and wherein the second cytotoxic drug is lipid soluble and incorporated into a lipid bilayer of the liposome.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.5974
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14020592', '14599291', '12891568', '14499201', '11371586']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7368834298747722
- 35 USC 102 Novelty (BERT): 0.4958575356789219
- Combined Prediction Score: 0.7127808404551872
- Mean Citation Score: 216.49398
- Max Citation Score: 224.96416
- Similarity Product: 151.9586853534317

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test