PATENT CLAIM ANALYSIS

Application Number: 16028140
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-06
Patent Classification: ["424", "133100"]

Abstract:
The present inventors newly discovered that even if an antigen-binding molecule inhibits in vitro some of the physiological activities of an antigen having two or more physiological activities without inhibiting the remaining physiological activities, the molecule can promote elimination of the antigen from blood (from serum or plasma) and as a result reduce the physiological activities in vivo, when the antigen-binding molecule is conferred with the properties: (i) of binding to human FcRn wider an acidic pH range condition; (ii) of binding under a neutral pH range condition to human Fc receptor stronger than native human IgG, and (iii) that its antigen-binding activity alters according to the ion concentration.

Claim (Index 58):
The method of  claim 54 , wherein the human Fc receptor of (d)(iii) is a human Fey receptor.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 95.0
- Lexical Diversity: 1.5974
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14007947', '14347448', '14101441', '13650493', '09825517']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7990978472287779
- 35 USC 102 Novelty (BERT): 0.6595233376791351
- Combined Prediction Score: 0.7851403962738136
- Mean Citation Score: 761.1392320000001
- Max Citation Score: 1081.3811
- Similarity Product: 628.8426329135538

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test