PATENT CLAIM ANALYSIS

Application Number: 15761371
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["506", "009000"]

Abstract:
The present disclosure relates to novel macrocyclic compounds and libraries thereof containing heteroaryl moieties that are useful as research tools for drug discovery efforts. The present disclosure also relates to methods of preparing these compounds and libraries and methods of using these libraries, such as in high throughput screening. In particular, these libraries are useful for evaluation of bioactivity at existing and newly identified pharmacologically relevant targets, including G protein-coupled receptors, nuclear receptors, enzymes, ion channels, transporters, transcription factors, protein-protein interactions and nucleic acid-protein interactions. As such, these libraries can be applied to the search for new pharmaceutical agents for the treatment and prevention of a range of medical conditions.

Claim (Index 46):
The method of  claim 44  wherein the biological target is an enzyme, a G protein-coupled receptor, a nuclear receptor, an ion channel, a transporter, a transcription factor, a protein-protein interaction or a nucleic acid-protein interaction.

Metadata:
- Claim Count in Document: 54.0
- Percentile: 90.0
- Lexical Diversity: 1.58974
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15672617', '10872142', '12474318', '13196658', '15475227']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5772159660938928
- 35 USC 102 Novelty (BERT): 0.5228369924871484
- Combined Prediction Score: 0.5717780687332183
- Mean Citation Score: 226.887216
- Max Citation Score: 234.46033
- Similarity Product: 126.94435874634505

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test