PATENT CLAIM ANALYSIS

Application Number: 15749191
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["536", "024500"]

Abstract:
Double-stranded modified siRNA targeting a RecQL1 helicase gene includes a sense strand including the nucleotide sequence shown in SEQ ID NO: 1, and an antisense strand including the nucleotide sequence shown in SEQ ID NO: 2, wherein the sense strand includes 2′-substituted nucleotides at positions 2, 3, 4 and 13 in the nucleotide sequence shown in SEQ ID NO: 1, the sense strand further includes a 2′-substituted nucleotide(s) at one or more positions selected from the group consisting of positions 12, 14, 17, 18 and 19 in the nucleotide sequence shown in SEQ ID NO: 1, wherein the position 2′ of the 2′-substituted nucleotides is —R 1 , —OR 1 , —R 2 OR 1 , —OR 2 OR 1  or —R 3 OR 2 OR 1 , wherein R 1  represents a C 1-4  alkyl group, and R 2  and R 3  independently represent a C 1-3  alkylene group.

Claim (Index 30):
An agent that induces cell death comprising the modified siRNA according to  claim 17 .

Metadata:
- Claim Count in Document: 2.0
- Percentile: 86.0
- Lexical Diversity: 2.47059
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12343342', '12673003', '15376633', '13764825', '11980102']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6704966827980751
- 35 USC 102 Novelty (BERT): 0.522348919350873
- Combined Prediction Score: 0.6556819064533549
- Mean Citation Score: 348.36243
- Max Citation Score: 353.0999
- Similarity Product: 255.17576364611983

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test