PATENT CLAIM ANALYSIS

Application Number: 16283629
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["435", "006100"]

Abstract:
The present disclosure provides a system and method for the detection of rare mutations and copy number variations in cell free polynucleotides. Generally, the systems and methods comprise sample preparation, or the extraction and isolation of cell free polynucleotide sequences from a bodily fluid; subsequent sequencing of cell free polynucleotides by techniques known in the art; and application of bioinformatics tools to detect rare mutations and copy number variations as compared to a reference. The systems and methods also may contain a database or collection of different rare mutations or copy number variation profiles of different diseases, to be used as additional references in aiding detection of rare mutations, copy number variation profiling or general genetic profiling of a disease.

Claim (Index 53):
The method of claim  1 , wherein the presence of at least one or more somatic genetic variants detected is a gene fusion.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 99.0
- Lexical Diversity: 1.84286
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16277712', '16283635', '15872831', '15978848', '14712754']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7348117511092679
- 35 USC 102 Novelty (BERT): 0.638003498939494
- Combined Prediction Score: 0.7251309258922906
- Mean Citation Score: 560.532898
- Max Citation Score: 591.4164400000002
- Similarity Product: 404.77377909136777

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test