PATENT CLAIM ANALYSIS

Application Number: 15748786
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["544", "350000"]

Abstract:
Compounds of the formula Ia or of the formula Ib in which X, Y, R 1  and R 2  have the meanings indicated in claim  1 , are inhibitors of pyruvate dehydrogenase kinase (PDHK), and can be employed, inter alia, for the treatment of diseases such as cancer.

Claim (Index 1):
Compounds of the formula Ia or of the formula Ib in which X denotes CH or N, Y denotes CH or N, R 1  denotes H, A, (CH 2 )\u2014Ar, (CH 2 ) n Het or Cyc, R 2  denotes H or CH 3 , Ar denotes phenyl, which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by Hal, A, CN, OA, [C(R 5 ) 2 ] p OH, [C(R 5 ) 2 ] p N(R 5 ) 2 , NO 2 , [C(R 5 ) 2 ] p COOR 5 , NR 5 COA, NR 5 SO 2 A, [C(R 5 ) 2 ] p SO 2 N(R 5 ) 2 , S(O) p A, O[C(R 5 ) 2 ] m N(R 5 ) 2 , NR 5 COOA, NR 5 CON(R 5 ) 2  and/or COA, Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms, which is unsubstituted or mono- or disubstituted by Hal, A, CN, OA, [C(R 5 ) 2 ] p OH, [C(R 5 ) 2 ] p N(R 5 ) 2 , NO 2 , [C(R 5 ) 2 ] p COOR 5 , NR 5 COA, NR 5 SO 2 A, [C(R 5 ) 2 ] p SO 2 N(R 5 ) 2 , S(O) p A, O[C(R 5 ) 2 ] m N(R 5 ) 2 , NR 5 COOA, NR 5 CON(R 5 ) 2  and/or COA, Cyc denotes cyclic alkyl with 3, 4, 5, 6 or 7 C-atoms, which is unsubstituted or monosubstituted by OH, A denotes unbranched or branched alkyl with 1-10 C-atoms, wherein one or two non-adjacent CH- and/or CH 2 -groups may be replaced by N-, O- and/or S-atoms and/or wherein 1-7 H-atoms may be replaced by R 4 , R 4  denotes F, Cl or OH, R 5  denotes H oder A\u2032, A\u2032 denotes unbranched or branched alkyl with 1-6 C-atoms, wherein 1-5 H-atoms may be replaced by F, Hal denotes F, Cl, Br or I, m denotes 1, 2, 3 or 4, n denotes 0, 1 or 2, p denotes 0, 1, 2, 3 or 4, with the proviso that, if X\u2550CH then Y\u2550N or if Y\u2550CH then X\u2550N,\n and pharmaceutically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 86.0
- Lexical Diversity: 1.4
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15105154', '09927324', '12298369', '14342749', '14420003']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.793533604090669
- 35 USC 102 Novelty (BERT): 0.5438446841794831
- Combined Prediction Score: 0.7685647120995504
- Mean Citation Score: 375.832478
- Max Citation Score: 391.2317
- Similarity Product: 288.2394445637703

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test