PATENT CLAIM ANALYSIS

Application Number: 15902622
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["514", "100000"]

Abstract:
Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.

Claim (Index 20):
The method of  claim 8 , wherein (a) is represented by formula (I): wherein\n X 1  is H, R 1 , OH or OR 1 , \n X 2  is H, R 1 , OH, OR 1 , \u2550O or Y, \n X 3  is H or OH, \n X 4  is H, OH or OR 1 , \n R 1  is a C 1-4  alkyl group, \n Y is (CR 2 R 3 O) n P(O)(O \u2212 Z + ) 2 , \n each R 2  is, independently, H, C 1-6  alkyl, aryl-C 1-6  alkyl-, C 3-6  cycloalkyl or aryl, \n each R 3  is, independently, H, C 1-6  alkyl, aryl-C 1-6  alkyl-, C 3-6  cycloalkyl or aryl, \n or R 2  and R 3 , together with the carbon atom to which they are bonded form a C 3-7  cycloalkyl group, \n wherein any alkyl or cycloalkyl group in R 2  or R 3  may be optionally substituted with one to five substituents selected from the group consisting of halo, C 1-6  alkoxy and NR a R b , \n wherein any aryl group in R 2  or R 3  may be optionally substituted with one to five substituents selected from the group consisting of C 1-6  alkyl, C 1-6  alkoxy, NR a R b , nitro and cyano, \n n is 1, 2 or 3, \n each Z is H, \n R a  and R b  are each, independently, H, C 1-6  alkyl, C 3-6  cycloalkyl or aryl, \n or R a  and R b , together with the nitrogen atom to which they are bonded, form a pyrrolidino, piperidino, piperanino, azetidino, morpholino, or thiomorpholino group, \n or a salt thereof.

Metadata:
- Claim Count in Document: 57.0
- Percentile: 88.0
- Lexical Diversity: 1.61111
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14423245', '13319316', '13938971', '15465377', '14836570']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7786195567079479
- 35 USC 102 Novelty (BERT): 0.5654131053290237
- Combined Prediction Score: 0.7572989115700555
- Mean Citation Score: 239.84066
- Max Citation Score: 517.4103
- Similarity Product: 319.45815047167537

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test