PATENT CLAIM ANALYSIS

Application Number: 15947098
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "017100"]

Abstract:
A scaffold for promoting cartilage formation is provided that includes a crosslinked electrospun fiber, wherein the crosslinked electrospun fiber consists essentially of crosslinked gelatin. The crosslinked electrospun fiber is generally crosslinked with a crosslinker, and the crosslinker may be diisosorbide bisepoxide. The crosslinked electrospun fiber may be crosslinked by adding a crosslinker to a solution of gelatin at a desired concentration. The electrospun fiber may advantageously remain intact for 18 days or longer upon being immersed in an aqueous solution. A composition for promoting cartilage formation is also provided that includes the disclosed scaffold and a mesenchymal stem cell (MSC). The disclosed scaffold may include a crosslinked electrospun fiber that includes gelatin and sodium cellulose sulfate (NaCS), e.g., in an amount of up to 5% by weight of the amount of gelatin. A method for promoting cartilage formation is also provided that includes administering to a subject in need thereof a disclosed composition for promoting cartilage formation in the subject.

Claim (Index 7):
The mimetic of  claim 1 , wherein the crosslinked hydrogel has been crosslinked by adding a crosslinker to a solution of gelatin and NaCS to achieve a concentration of the crosslinker in the solution of about 5% based on solid weight of the solution.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 91.0
- Lexical Diversity: 2.31579
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12661242', '13552550', '13097657', '12420088', '14497274']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7518771094758349
- 35 USC 102 Novelty (BERT): 0.505055120294111
- Combined Prediction Score: 0.7271949105576625
- Mean Citation Score: 201.470142
- Max Citation Score: 241.61855
- Similarity Product: 163.9624664456159

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test