PATENT CLAIM ANALYSIS

Application Number: 16065397
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "387000"]

Abstract:
Presently provided are inhibitors of cellularly expressed TDO2 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2, 3 dioxygenase; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.

Claim (Index 10):
The compound of  claim 3  wherein,\n R 1  is \n ring A is C 3-8 cycloalkyl or 3-7 membered heterocyclyl; ring B is aryl, heteroaryl, C 3-7 cycloalkyl or 3-7 membered heterocyclyl; m is 0, 1, 2, 3 or 4; each R a  is independently selected from oxo, halogen, cyano, nitro, C 1-6 alkyl, \u2014C 1-6 haloalkyl, C 1-6 alkyl-cyano, \u2014OR, \u2014NR 2 , \u2014SR, \u2014C(O)OR, \u2014C(O)N(R) 2 , \u2014C(O)R, \u2014S(O)R, \u2014S(O)OR, \u2014S(O)N(R) 2 , \u2014S(O) 2 R, \u2014S(O) 2 OR, \u2014S(O) 2 N(R) 2 , \u2014OC(O)R, \u2014OC(O)OR, \u2014OC(O)N(R) 2 , \u2014N(R)C(O)R, \u2014N(R)C(O)OR, and \u2014N(R)C(O)N(R) 2 ; and the hydroxy moiety is bonded to the A ring and each R a  is independently a substituent of the A ring or the B ring.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.34783
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12666423', '15122863', '14061616', '16472185', '13897927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8183673311607352
- 35 USC 102 Novelty (BERT): 0.5345898548019687
- Combined Prediction Score: 0.7899895835248586
- Mean Citation Score: 367.118278
- Max Citation Score: 369.48654
- Similarity Product: 267.58012994710924

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test