PATENT CLAIM ANALYSIS

Application Number: 16050069
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "456000"]

Abstract:
The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoarthritis and rheumatoid arthritis and for promoting overall joint health. This is accomplished by totally addressing the key multiple biochemical processes and mechanisms that lead to such disorders. The invention includes compositions comprising a combination of natural agents that safely and effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that increase the risk for or lead to the development and/or progression of OA and RA. The present compositions are holistically formulated to be effective in preventing/arresting loss of and/or damage to the articular cartilage (AC) by suppressing (a) extracellular matrix (ECM) degradation, (b) chondrocyte apoptosis, and (c) inflammation of synovium through modulation of mechanisms that involve transcription factors, growth factors, kinases, antiapoptotic/apoptotic factors and deacetylases. The active agents used herein are natural materials, in particular phytonutrients (or phytochemicals), minerals and/or vitamins.

Claim (Index 13):
A method according to  claim 10  wherein the composition comprises magnesium (Mg) and at least four phytonutrients as active agents, wherein the phytonutrients are selected from quercetin; curcumin; resveratrol; oleuropein; hydroxytyrosol; epigallocatechin-3-gallate (EGCG); procyanidins; catechin; epicatechin (EC); epicatechin gallate (ECG); epigallocatechin (EGC); genistein; daidzein; myricetin; hesperitin; hesperidin; magnolol; honokiol; kaempferol; psi-baptigenin; apigenin; gingerol; lutein; zeazanthin; oleocanthal; boswellic acid; rosmarinic acid; luteolin; amorfrutins; mangiferin; salacinol; kotalanol; robinetinidol; fisetinidol; berberine;  Polypodium ; salicortin; and glycosides, gallates, other derivatives or plant extract sources thereof and wherein Mg is supplied as a chloride, sulfate, carbonate, oxide, citrate, malate, aspartate, glutamate, taurate or bisglycinate compound or complex.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 95.0
- Lexical Diversity: 1.74257
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12373584', '12048613', '15265009', '15308725', '12861152']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7706938451918036
- 35 USC 102 Novelty (BERT): 0.4898452648343829
- Combined Prediction Score: 0.7426089871560616
- Mean Citation Score: 208.79038600000004
- Max Citation Score: 223.04387000000003
- Similarity Product: 169.6974273309094

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test