PATENT CLAIM ANALYSIS

Application Number: 15904248
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "450000"]

Abstract:
Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.

Claim (Index 14):
A composition for immunomodulation to achieve antigen-specific tolerance, the composition comprising:\n one or more antigens fused or chemically conjugated with an erythrocyte-binding moiety; wherein said one or more antigens is selected from the group consisting of proinsulin and immunogenic fragments thereof, and immunogenic mimotopes thereof; wherein said one or more antigens being recognizable by an immune system of a subject, the immune system of the subject being able to respond to or previously having responded to the one or more antigens with an unwanted immune response, said erythrocyte-binding moiety having the ability to non-covalently, specifically bind an erythrocyte surface in situ in blood and present said one or more antigens to the immune system of the subject, wherein said erythrocyte-binding moiety comprises at least an antibody or an antibody fragment.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 1.38182
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15904228', '15904254', '15232724', '15232714', '15232713']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8387932767051902
- 35 USC 102 Novelty (BERT): 0.7045962400370863
- Combined Prediction Score: 0.8253735730383799
- Mean Citation Score: 762.299016
- Max Citation Score: 782.65906
- Similarity Product: 727.3841314904082

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test