PATENT CLAIM ANALYSIS

Application Number: 16377465
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-07
Patent Classification: ["436", "501000"]

Abstract:
The present invention relates to an in vitro method for the prognosis of an adverse event in asymptomatic subjects comprising the determination of the level of Procalcitonin (PCT) or a fragment thereof or a precursor or fragment thereof having at least 12 amino acid residues in a sample of a bodily fluid from said subject and the correlation of the determined level to a potential risk of sustaining an adverse event.

Claim (Index 23):
The method of  claim 18 , wherein the risk determination is performed by\n comparing the determined PCT or PCT fragment level with the median of the level of PCT or fragments thereof in an ensemble of predetermined samples from a population of apparently healthy subjects, or comparing the determined PCT or PCT fragment level with a quantile of the level of PCT or fragments thereof in an ensemble of predetermined samples from a population of apparently healthy subjects, or performing calculations based on Cox Proportional Hazards analysis or on risk index calculations such as the Net Reclassification Index (NRI) or the Integrated Discrimination Index (IDI).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 100.0
- Lexical Diversity: 1.5102
- Patent Class: 436.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15211802', '14391953', '12671823', '14223517', '14939595']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6930134754651923
- 35 USC 102 Novelty (BERT): 0.5147314937223767
- Combined Prediction Score: 0.6751852772909108
- Mean Citation Score: 244.818922
- Max Citation Score: 311.54398
- Similarity Product: 175.4978718956911

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test