PATENT CLAIM ANALYSIS

Application Number: 15975493
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["424", "172100"]

Abstract:
The present invention relates to a protein binding to GARP in the presence of TGF-ß and uses thereof.

Claim (Index 10):
The protein according to  claim 1 , wherein the protein is an antibody or antigen binding fragment thereof, and wherein the variable region of the heavy chain comprises the following CDRs: GFSLTGYGIN (SEQ ID NO: 2), MIWSDGSTDYNSVLTS (SEQ ID NO: 3), DRNYYDYDGAMDY (SEQ ID NO: 4), and the variable region of the light chain comprises the following CDRs: KASDHIKNWLA (SEQ ID NO: 5), GATSLEA (SEQ ID NO: 6), QQYWSTPWT (SEQ ID NO: 7), or any CDR having an amino acid sequence that shares at least 60% of identity with said SEQ ID NO: 2-7;\n or wherein the variable region of the heavy chain comprises the following CDRs: GYGIN (SEQ ID NO: 52), MIWSDGSTDYNSVLTS (SEQ ID NO: 3), DRNYYDYDGAMDY (SEQ ID NO: 4), and the variable region of the light chain comprises the following CDRs: KASDHIKNWLA (SEQ ID NO: 5), GATSLEA (SEQ ID NO: 6), QQYWSTPWT (SEQ ID NO: 7), or any CDR having an amino acid sequence that shares at least 60% of identity with said SEQ ID NO: 52 and 3-7; or wherein the variable region of the heavy chain comprises the following CDRs: SYYID (SEQ ID NO: 13), RIDPEDGGTKYAQKFQG (SEQ ID NO: 14), NEWETVVVGDLMYEYEY (SEQ ID NO: 15); and the variable region of the light chain comprises the following CDRs: QASQX 1 IX 2 SX 3 LA (SEQ ID NO: 16), wherein X 1  is S or T; X 2  is S or V; X 3  is Y or F; X 1 X 2 SX 3 X 4 X 5 T (SEQ ID NO: 17), wherein X 1  is G or R; X 2  is A or T; X 3  is R or I; X 4  is L or P; X 5  is Q or K; QQYX 1 SX 2 PX 3 T, wherein X 1  is D, A, Y or V; X 2  is A, L or V; X 3  is V or P (SEQ ID NO: 18); or any CDR having an amino acid sequence that shares at least 60% of identity with said SEQ ID NO: 16-18.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 93.0
- Lexical Diversity: 1.05556
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14908368', '13288587', '15517108', '14279728', '13024698']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7426140100155909
- 35 USC 102 Novelty (BERT): 0.6383571619948345
- Combined Prediction Score: 0.7321883252135153
- Mean Citation Score: 443.03607
- Max Citation Score: 706.23926
- Similarity Product: 520.3138656332945

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test