PATENT CLAIM ANALYSIS

Application Number: 16094535
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-07
Patent Classification: ["552", "553000"]

Abstract:
The present application relates to a method of preparing a bile acid derivative, or a pharmaceutical acceptable salt, solvate, or amino acid conjugate thereof, comprising reacting Compound 2 with paraldehyde to form Compound 3:

Claim (Index 24):
A method of preparing Compound of Formula III comprising reacting Compound of Formula I with paraldehyde to form Compound of Formula II wherein:\n A is \n oxadiazolonyl, or isoxazolonyl, wherein the carbon atom marked with \u201c*\u201d is bonded to the carbon atom to which A is bonded;\n n is 0, 1, or 2; \n R 1 , R 2 , and R 4  are each independently H or OH; \n R 3  is (CR 5 R 6 ) p C(O)OH, (CR 5 R 6 ) p OH, (CR 5 R 6 ) p OSO 3 H; (CR 5 R 6 ) p SO 3 H; C(O)NHR 7 , tetrazolyl, oxadiazolyl, oxadiazolonyl, or thiazolidine-dionyl optionally substituted with NHS(O) 2 \u2014(C 1 -C 3 ) alkyl; \n R 5  and R 6  are each independently H, halogen, OH, or alkyl optionally substituted with OH or halogen, \n R 7  is OH, (CH 2 ) p OH, or (CH 2 ) p OSO 3 H; \n p is 1 or 2; and \n wherein the hydroxyl groups of R 1 , R 2 , and R 4  may be protected.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 97.0
- Lexical Diversity: 1.3
- Patent Class: 552.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15773620', '15748716', '15750683', '14947680', '15496398']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5827639053404509
- 35 USC 102 Novelty (BERT): 0.5844595113994007
- Combined Prediction Score: 0.5829334659463459
- Mean Citation Score: 224.662612
- Max Citation Score: 262.33447
- Similarity Product: 193.3557937409532

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test