PATENT CLAIM ANALYSIS

Application Number: 16094770
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["514", "301000"]

Abstract:
2-Aminothiophene derivatives, uses of the same, and methods of making the same, are described.

Claim (Index 1):
A compound comprising Formula I: wherein: dashed lines represent optional bonds; Z is N, O, or S; R 1  is a lone pair of electrons, H, C 1 -C 8  acyl, C 1 -C 8  aminoalkyl, or: (a) C 1 -C 8  alkyl optionally substituted with one or more of the following: F, Cl, hydroxy, C 1 -C 8  alkyl, C 1 -C 8  acyloxy, C 1 -C 8  aminoalkyl, Ph or vinyl, C 3 -C 6  cycloalkyl, or Ph optionally substituted with one or more of the following: F, Cl, hydroxy, C 1 -C 8  alkyl, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph, vinyl, CN, CO 2 H, C(O)NR 4 , C(O)OR 4 ; (b) C 1 -C 8  alkenyl optionally substituted with one or more of the following: F, Cl, hydroxy, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph or vinyl, C 3 -C 6  cycloalkyl, or Ph optionally substituted with one or more of the following: F, Cl, hydroxy, C 1 -C 8  alkyl, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph, vinyl, CN, CO 2 H, C(O)NR 4 , or C(O)OR 4 ; (c) Ph optionally substituted with one or more of the following: F, Cl, hydroxy, C 1 -C 5  alkyl, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph, vinyl, CN, CO 2 H, C(O)NR 4 , or C(O)OR 4 , wherein R 4  is independently Ph or C 1 -C 8  alkyl, optionally substituted with one or more of: hydroxy, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, Ph, or vinyl; or (d) C 3 -C 6  cycloalkyl; provided, however, that when Z is O or S, then R 1  is a lone pair of electrons; R 2  is independently H, F, Cl, C 1 -C 8  alkyl, C 3 -C 6  cycloalkyl, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, C 1 -C 8  aminoalkyl, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph, vinyl, CN, CO 2 H, C(O)OR 4 , or C(O)NR 4 ; R 3  is Ph optionally substituted with one to five of: F, Cl, hydroxy, C 1 -C 8  alkyl, C 1 -C 8  alkoxy, C 1 -C 8  acyloxy, amino, C 1 -C 8  alkylamino, C 1 -C 8  dialkylamino, O\u2014CH 2 -Ph, Ph, vinyl, CN, CO 2 H, C(O)NR 4 , or C(O)OR 4 ; each X, when present, is independently O, NH, 2H, or S; Y is S, O, NH, NR 4 , or CH 2 ; and n is 1 or 2; and salts, stereoisomes, racemates, hydrates, solvates, prodrugs, and polymorphs thereof.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 97.0
- Lexical Diversity: 1.38462
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12999095', '13754499', '11911525', '13381587', '13348500']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7205479879715799
- 35 USC 102 Novelty (BERT): 0.52118317942956
- Combined Prediction Score: 0.700611507117378
- Mean Citation Score: 309.747552
- Max Citation Score: 320.0987
- Similarity Product: 224.7794874208868

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test