PATENT CLAIM ANALYSIS

Application Number: 16281835
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-07
Patent Classification: ["424", "502000"]

Abstract:
Disclosed are methods useful for the topical therapeutic treatment of skin keratoses including precancerous skin keratoses such as actinic keratosis using compositions containing nanoparticles of paclitaxel or other taxanes.

Claim (Index 99):
A method of treating a skin keratosis in a subject in need of treatment, the method comprising topically administering to an affected area of the subject an anhydrous hydrophobic composition comprising a suspension of 0.1% w/w to 5% w/w of a plurality of nanoparticles of non-solubilized taxane, petrolatum, and 5% w/w to 24% w/w of cyclomethicone,\n wherein the nanoparticles of non-solubilized taxane are uncoated (neat) individual particles of non-solubilized taxane, wherein the non-solubilized taxane is not bound to or conjugated to any substance, wherein the nanoparticles of non-solubilized taxane have a mean particle size (number) from 0.1 microns to 1.5 microns, and wherein the skin keratosis is actinic keratosis.

Metadata:
- Claim Count in Document: 77.0
- Percentile: 99.0
- Lexical Diversity: 1.11111
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16281907', '15899228', '12741954', '14692665', '13568003']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6745838923010495
- 35 USC 102 Novelty (BERT): 0.5998367589463399
- Combined Prediction Score: 0.6671091789655785
- Mean Citation Score: 215.971628
- Max Citation Score: 319.51654
- Similarity Product: 308.77283229883665

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test