PATENT CLAIM ANALYSIS

Application Number: 15779353
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["514", "210180"]

Abstract:
The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.

Claim (Index 29):
The compound of  claim 1 , or a pharmaceutically acceptable salt thereof, wherein:\n X is CH or N; Z is CH or N; with the proviso that when X is CH, Z is not also CH; Y is selected from the group consisting of H, NR 6 R 7 , \u2014C(O)R 11 , \u2014C(O)NR 11 R 12 , 4-10 membered heterocycloalkyl, and 5-10 membered heteroaryl, wherein said 4-10 membered heterocycloalkyl and 5-6 membered heteroaryl may optionally be substituted with 1, 2, 3, or 4 independently selected R 8 ; R 1  and R 2 , together with the included nitrogen atom and L 1 , form a heterocycloalkyl group selected from the group consisting of: R 3  is selected from the group consisting of H, 5-6 membered heterocycloalkyl, and 5-6 membered heteroaryl, wherein said 5-6 membered heterocycloalkyl and 5-6 membered heteroaryl may optionally be substituted with 1, 2, 3, or 4 independently selected R 8 ; R 4  is H; each R 6  is independently selected from the group consisting of H and C 1-6  alkyl; each R 7  is an independently selected C 1-6  alkyl group, each of which may optionally be substituted by 1, 2, 3, or 4 independently selected R 8 ; each R 8  is independently selected from the group consisting of C 1-6  alkyl, C 3-6  cycloalkyl, 5-6 membered heterocycloalkyl, phenyl, OR 11 , \u2014C(O)R 11 , \u2014C(O)OR 11 , \u2014C(O)NR 11 R 12 , S(O) 2 R 11 , wherein said C 1-6  alkyl, 5-6 membered heterocycloalkyl, and phenyl are each optionally substituted with 1, 2, 3, or 4 independently selected R 14 ; each R 11  is independently selected from the group consisting of H, C 1-6  alkyl, C 3-6  cycloalkyl, 4-6 membered heterocyloalkyl, 5-6 membered heteroaryl, wherein said C 1-6  alkyl, C 3-6  cycloalkyl, 4-6 membered heterocycloalkyl, and 5-6 membered heteroaryl may optionally be substituted with 1, 2, 3, or 4 independently selected R 14 ; each R 12  is independently selected from the group consisting of H and C 1-6  alkyl; each R 14  is independently selected from the group consisting of halogen, C 1-6  alkyl, phenyl, 4-6 membered heterocycloalkyl, 5-6 membered heteroaryl, OR 18 , NR 18 R 19 , C(O)R 18 , C(O)NR 18 R 19 , and S(O) 2 R 18 , wherein said phenyl, 4-6 membered heterocycloalkyl, and 5-6 membered heteroaryl may optionally be substituted with 1, 2, 3, or 4 independently selected R 15 ; each R 15  is CH 3  or CN; each R 18  is independently selected from the group consisting of H and C 1-6  alkyl; and each R 19  is independently selected from the group consisting of H and C 1-6  alkyl; and R 21  is C 1-6  alkyl, C 3-6  cycloalkyl, 4-7 membered heterocycloalkyl, 5-6 membered heteroaryl, phenyl, \u2014C(O)R 11 , \u2014C(O)OR 11 , \u2014C(O)NR 11 R 12 , or \u2014S(O) 2 R 11 , wherein said C 1-6  alkyl, C 3-6  cycloalkyl, 4-7 membered heterocycloalkyl, 5-6 membered heteroaryl, and phenyl are each optionally substituted with 1, 2, or 3 independently selected R 14 .

Metadata:
- Claim Count in Document: 3.0
- Percentile: 93.0
- Lexical Diversity: 1.48485
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15398907', '15906163', '14977508', '15110361', '15424616']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8103097742867823
- 35 USC 102 Novelty (BERT): 0.5377100342399728
- Combined Prediction Score: 0.7830498002821014
- Mean Citation Score: 352.129134
- Max Citation Score: 384.88992
- Similarity Product: 305.3409402241516

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test