PATENT CLAIM ANALYSIS

Application Number: 15742027
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["427", "002100"]

Abstract:
An asymmetric immobilization process that immobilizes a one or more receptor biomolecules on one or more solid surfaces is provided. The asymmetric immobilization process includes the following steps: (i) activating the one or more solid surfaces using an oxidizing agent; (ii) treating the one or more solid surfaces with aminosilane to obtain a one or more amine functionalized solid surfaces; (iii) treating the one or more receptor biomolecules with a 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) to obtain a one or more site-specific EDC activated receptor biomolecules; and (iv) immobilizing the one or more site-specific EDC activated receptor biomolecules on a first layer of the one or more amine functionalized solid surfaces, wherein the immobilizing comprises treating the one or more site-specific EDC activated receptor biomolecules with amine groups of the first layer of the one or more amine functionalized solid surfaces to form a covalent amide bond.

Claim (Index 10):
The asymmetric immobilization process as claimed in  claim 9 , wherein the plurality of receptor biomolecules is selected from a group comprising:\n (i) an anti-myoglobin antibody; (ii) an anti-FABP3 antibody; (iii) an anti-troponin antibody; (iv) an anti-Human IgG antibody; (v) an anti-IMA Antibody; (vi) an anti-Myeloperoxidase (MPO) Antibody; (vii) an anti-Glycogen Phosphorylase Isoenzyme BB-(GPBB) Antibody; (viii) an anti-Serum creatinine antibody; (ix) an anti-Serum cystatin C antibody; (x) an anti-Urine albumin antibody; (xi) an anti-Neutrophil gelatinase-associated lipocalin (NGAL) antibody; (xii) an anti-Kidney injury molecule 1 (KIM-1) antibody; (xiii) an anti-Liver-type fatty acid-binding protein (L-FABP) antibody; (xiv) an anti-Interleukin 18 (IL-18), \u03b2-trace protein (BTP) antibody; (xv) an anti-Aasymmetric dimethylarginine (ADMA) antibody; and (xvi) an anti-Urine cystatin C antibody.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 86.0
- Lexical Diversity: 2.66129
- Patent Class: 427.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12317713', '10293260', '12119203', '11621209', '09845742']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7863999001486096
- 35 USC 102 Novelty (BERT): 0.5099358030666786
- Combined Prediction Score: 0.7587534904404165
- Mean Citation Score: 198.672414
- Max Citation Score: 231.09346
- Similarity Product: 140.30856373933196

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test