PATENT CLAIM ANALYSIS

Application Number: 15743546
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["546", "153000"]

Abstract:
Compounds that inhibit Myeloid Cell Leukemia-1 (Mcl-1) oncoprotein, and methods of using the same, are provided for treating disease.

Claim (Index 8):
The compound of  claim 7 , wherein the compound is selected from the group consisting of 1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid,\n 1-((4-bromophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((4-phenoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(naphthalen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((4-(3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((4-(p-tolylthio)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((benzyloxy)carbonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(isobutoxycarbonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(4-phenoxybenzyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, phenyl 1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylate, 1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxamide, methyl 1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylate, acetoxymethyl 1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylate, 1-((4-fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-([1,1\u2032-biphenyl]-4-ylsulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((4-(p-tolyloxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-(quinolin-8-ylsulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, 1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, (\u00b1)-1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-((4-bromophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-((4-fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-([1,1\u2032-biphenyl]-4-ylsulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-(naphthalen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-((4-(4-chloro-3,5-dimethylphenoxy)phenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, (\u00b1)-1-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid, 4-(N-isobutylphenylsulfonamido)benzoic acid, and the pharmaceutically acceptable salts, solvates, hydrates, cocrystals, or prodrugs thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.04348
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12104294', '12096393', '14763468', '13823810', '13526337']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7879684413724609
- 35 USC 102 Novelty (BERT): 0.5117853440276781
- Combined Prediction Score: 0.7603501316379826
- Mean Citation Score: 268.77087199999994
- Max Citation Score: 276.15472
- Similarity Product: 191.99904757661807

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test