PATENT CLAIM ANALYSIS

Application Number: 16013619
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["424", "186100"]

Abstract:
The present disclosure provides a method to enhance the production of virus in cultured fibroblasts by supplementing the cells with a TCA cycle intermediate, aketoglutarate, or a derivative thereof, wherein virus production is enhanced compared to the same method canied out in the absence of a-ketoglutarate or the derivative thereof. In view of the art, the method provides an unexpected improvement on methods routinely practiced.

Claim (Index 109):
The method of any one of  claims 10 - 105 ,  107  and  108  wherein the fatty acid is present at a concentration of no more than 5 \u03bcM, no more than 10 \u03bcM, no more than 15 \u03bcM, no more than 20 \u03bcM, no more than 25 \u03bcM, no more than 30 \u03bcM, no more than 35 \u03bcM, no more than 40 \u03bcM, no more than 45 \u03bcM, no more than 50 \u03bcM, no more than 55 \u03bcM, no more than 60 \u03bcM, no more than 65 \u03bcM, no more than 70 \u03bcM, no more than 75 \u03bcM, no more than 80 \u03bcM, no more than 85 \u03bcM, no more than 90 \u03bcM, no more than 95 \u03bcM, no more than 100 \u03bcM, no more than 110 \u03bcM, no more than 120 \u03bcM, no more than 130 \u03bcM, no more than 140 \u03bcM, or no more than 150 \u03bcM.

Metadata:
- Claim Count in Document: 25.0
- Percentile: 94.0
- Lexical Diversity: 1.51064
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14112824', '13438616', '14543321', '13055587', '12156517']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7062542847495241
- 35 USC 102 Novelty (BERT): 0.5275219766633348
- Combined Prediction Score: 0.6883810539409052
- Mean Citation Score: 164.851584
- Max Citation Score: 300.48376
- Similarity Product: 160.07427266469003

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test