PATENT CLAIM ANALYSIS

Application Number: 15918324
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "183000"]

Abstract:
A novel function for the p53 gene related to resolution of deep venous thrombosis is disclosed herein. Lack of the p53 gene results in impaired thrombus resolution in a clinically relevant in vivo model of deep venous thrombus resolution. It is further shown that augmentation of p53 activity with quinacrine accelerates thrombus resolution in vivo, and that this beneficial effect is completely dependent on p53. p53-based therapy is therefore provided to accelerate thrombus resolution in patients, and to prevent or ameliorate the debilitating long-term complications of deep venous thrombosis such as post-thrombotic syndrome.

Claim (Index 10):
The method of  claim 6 , wherein the p53-encoding nucleic acid is in an expression cassette.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 90.0
- Lexical Diversity: 1.62295
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13501278', '15232773', '14617149', '13747307', '10280444']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.765899954969251
- 35 USC 102 Novelty (BERT): 0.5711073059256625
- Combined Prediction Score: 0.7464206900648921
- Mean Citation Score: 277.376238
- Max Citation Score: 560.62537
- Similarity Product: 325.7380932129311

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test