PATENT CLAIM ANALYSIS

Application Number: 15884752
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["548", "301100"]

Abstract:
The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

Claim (Index 27):
A method of treating or reducing the risk of a disease or condition selected from Down's syndrome, \u03b2-amyloid angiopathy, cerebral amyloid angiopathy, MCI (\u201cmild cognitive impairment\u201d), neurodegeneration associated with Alzheimer's disease, neurodegeneration associated with dementia, pre-senile dementia, senile dementia, dementia associated with Parkinson's disease, and cortical basal degeneration, wherein said method comprises administering to a person suffering from, or at risk of, said disease or condition, a therapeutically effective amount of a pharmaceutical composition comprising:\n a therapeutically effective amount of a compound which is (1r,1\u2032R,4R)-4\u2033-amino-5\u2033-methyl-6\u2032-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3\u2032H-dispiro[cyclohexane-1,2\u2032-indene-1\u2032,2\u2033-imidazol]-4-ol or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient, carrier or diluent.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.75
- Patent Class: 548.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14486959', '13331284', '13833221', '13916701', '13916754']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.751775228639781
- 35 USC 102 Novelty (BERT): 0.6506833221204857
- Combined Prediction Score: 0.7416660379878515
- Mean Citation Score: 474.920778
- Max Citation Score: 614.2726
- Similarity Product: 602.7854804728986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test