PATENT CLAIM ANALYSIS

Application Number: 15766667
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "300000"]

Abstract:
The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.

Claim (Index 21):
The compound of  claim 1 , represented by: wherein\n X is O or S; \n R A1  is selected from the group consisting of hydrogen and C 1-6 alkyl; \n R 1  is selected from the group consisting of \u2014C(O)OH and a 5-6 membered monocyclic heteroaryl having one, two, three, or four heteroatoms each selected from the group consisting of O, N, and S; wherein said heteroaryl may optionally be substituted by one or two substituents each independently selected from the group consisting of halogen, hydroxyl, and C 1-4 alkyl; \n R 2  is selected from the group consisting of hydrogen, halogen, cyano, C 1-6 alkyl, C 1-6 alkoxy, and C 3-6 cycloalkyl; \n Y is O or S(O) w  (where w is 0, 1 or 2); \n R 25  and R 26  are each independently selected from the group consisting of hydrogen and C 1-6 alkyl; \n p is 0 or 1; and \n B is a 4-10 membered monocyclic, bridged bicyclic, or spirocyclic heterocyclic ring having one or two heteroatoms each independently selected from the group consisting of O, N, and S; wherein if said heterocyclic ring contains an \u2014NH moiety, that nitrogen may optionally be substituted by a substituent selected from the group consisting of C 1-6 alkyl, \u2014C(O)\u2014C 1-6 alkyl, \u2014C(O)\u2014O\u2014C 1-6 alkyl, and \u2014S(O) w \u2014C 1-3 alkyl (where w is 0, 1, or 2); and wherein said heterocyclic ring may optionally be substituted by one, two, three, or four substituents each independently selected from hydroxyl, C 1-6 alkyl, C 1-6 alkoxy, and oxo.

Metadata:
- Claim Count in Document: 140.0
- Percentile: 91.0
- Lexical Diversity: 1.04545
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15747290', '15539392', '16091401', '15539397', '15320172']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8345855555121998
- 35 USC 102 Novelty (BERT): 0.5324654101745195
- Combined Prediction Score: 0.8043735409784318
- Mean Citation Score: 357.125496
- Max Citation Score: 371.4623
- Similarity Product: 306.2440399067164

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test