PATENT CLAIM ANALYSIS

Application Number: 15959686
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "210160"]

Abstract:
The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.

Claim (Index 17):
A method for treating an IRAK-mediated disorder in a patient in need thereof, comprising the step of administering to said patient a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein: \u2003is selected from each R a  is independently \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; Ring X is a C 3-10  aryl; a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a fused C 3-10  aryl, a fused 5-10 membered saturated or partially unsaturated carbocyclic ring, a fused 5-10 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a fused 5-10 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; R 1  is \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; R 2  is \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; R 3  is C 1-6  aliphatic, a 3-8 membered saturated or partially unsaturated carbocylic ring, or a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; or R 3  is -haloalkyl; R 4  is \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; Z is N or CR; each R is independently hydrogen, C 1-6  aliphatic, C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; or two R groups on the same atom are taken together with the atom to which they are attached to form a C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; and p is 0, 1, 2, 3, 4, or 5.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 91.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15267565', '15267606', '15701842', '14945610', '15450463']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7828173375068592
- 35 USC 102 Novelty (BERT): 0.5711440710089356
- Combined Prediction Score: 0.7616500108570669
- Mean Citation Score: 434.42543200000006
- Max Citation Score: 505.85544
- Similarity Product: 333.49232514804845

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test