PATENT CLAIM ANALYSIS

Application Number: 15895120
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["514", "003800"]

Abstract:
Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.

Claim (Index 33):
A compound of  claim 32 , wherein R 6  and R 8  are independently C 1-6 alkyl.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 88.0
- Lexical Diversity: 1.46032
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11199899', '11578626', '11596028', '11106879', '11786217']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8479168833379108
- 35 USC 102 Novelty (BERT): 0.5594511956323589
- Combined Prediction Score: 0.8190703145673557
- Mean Citation Score: 419.831592
- Max Citation Score: 430.53482
- Similarity Product: 320.3725991315603

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test