PATENT CLAIM ANALYSIS

Application Number: 16418272
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-10
Patent Classification: ["435", "007940"]

Abstract:
A method is described for the detection of at least two of cytokeratins 8, 18 and 19 in a sample. It is practiced by contacting the sample with a solid phase having a first antibody with specificity for cytokeratin 8, a second antibody with specificity for cytokeratin 18 and, optionally, a third antibody with specificity for a first epitope of cytokeratin 19 bound to it and allowing cytokeratins in the sample to bind to the bound antibodies to form complexes. The complexes are then contacted with a first labelled antibody with specificity for a dimer of cytokeratin 8 and 18 and optionally a second labelled antibody with specificity for a second epitope of cytokeratin 19 and allowing the labelled antibodies to bind to the complexes. The labelled antibodies bound to the complexes are then detected. A method for quantitative determination of soluble fragments of at least two of cytokeratin 8, 18 and 19 in a sample and a kit are also described.

Claim (Index 22):
The method according to  claim 21 , wherein said first immobilized antibody is 6D7, said second immobilized antibody is 3F3, and, if present, said third immobilized antibody is IDLC4.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 100.0
- Lexical Diversity: 2.96552
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14782527', '15127644', '14992750', '13821844', '10480848']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6321423362429417
- 35 USC 102 Novelty (BERT): 0.6256055563072056
- Combined Prediction Score: 0.6314886582493682
- Mean Citation Score: 309.454316
- Max Citation Score: 673.39233
- Similarity Product: 507.25878347637536

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test