PATENT CLAIM ANALYSIS

Application Number: 16166689
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["424", "190100"]

Abstract:
The present invention includes compositions and methods of preparing flagellar-coiling protein 1 (Fcp1)-deficient  Leptospira  bacterium. In one aspect, the invention includes an isolated, flagellar-coiling protein 1 (Fcp1)-deficient  Leptospira  bacterium. Another aspect includes a composition comprising a flagellar-coiling protein 1 (Fcp1) deficient  Leptospira  bacterium. Yet another aspect includes a method of producing a motility-deficient  Leptospira  bacterium comprising inhibiting expression of a wild-type flagellar-coiling protein 1 (Fcp1) gene. Methods of stimulating an immune response and reducing or treating an infectious disease caused by one or more  Leptospira  bacteria in a subject in need thereof comprising administering a composition comprising an effective amount of flagellar-coiling protein 1 (Fcp1) deficient  Leptospira  bacteria to the subject are also included.

Claim (Index 30):
The method of  claim 29 , wherein the adjuvant is selected from the group consisting of an oil-in-water emulsion, a saponin, a cholesterol, a phospholipid, a CpG, a polysaccharide, variants thereof, and a combination thereof.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 97.0
- Lexical Diversity: 2.07812
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15124633', '13216214', '13078879', '13359354', '12728177']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7966532364662096
- 35 USC 102 Novelty (BERT): 0.593578703587919
- Combined Prediction Score: 0.7763457831783805
- Mean Citation Score: 377.809246
- Max Citation Score: 706.5204
- Similarity Product: 415.9500340546846

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test