PATENT CLAIM ANALYSIS

Application Number: 15873473
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["424", "489000"]

Abstract:
The present invert on relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and two or more different polylactide-co-glycolide polymers (PLGAs).

Claim (Index 16):
A process of manufacturing the sustained release pharmaceutical composition according to  claim 2 , wherein the polylactide-co-glycolide polymers (PLGAs) are present in a mixture of depots, comprising\n (i) preparation of an internal organ phase comprising (ia) dissolving one PLGA polymer in a organic solvent or solvent mixture; (ib) dissolving/suspending/emulsification of octreotide or an aqueous solution of octreotide in the polymer solution obtained in step (ia); (ii) preparation of an external aqueous phase containing stabilizers; (iii) mixing the internal organic phase with the external aqueous phase to form an emulsion; (iv) hardening the microparticles by solvent evaporation or solvent extraction, washing the microparticles, drying the microparticles; and (v) mixing the obtained microparticles with the other microparticles obtained from the same process except the PLGA polymer used in that process is different, and wherein the lactide glycol de ratios of the different PLGAs are different from each other.

Metadata:
- Claim Count in Document: 42.0
- Percentile: 86.0
- Lexical Diversity: 1.03448
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13472219', '10565401', '13408472', '10564494', '13258808']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6549394056848261
- 35 USC 102 Novelty (BERT): 0.5741259808795752
- Combined Prediction Score: 0.6468580632043011
- Mean Citation Score: 280.17915400000004
- Max Citation Score: 477.6233
- Similarity Product: 359.13900251809355

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test