PATENT CLAIM ANALYSIS

Application Number: 16247425
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["514", "452000"]

Abstract:
Provided herein are compounds, compositions containing the compounds, and methods for the treatment of cancer in a cancer patient. In particular, the compounds are made by a process comprising treating a first compound represented by either Formula G′ or Formula M′: with a second compound of generalized formula R 8 R 9 C(OCH 3 ) 2  and an acid selected from the group consisting of camphor sulfonic acid (CSA), p-toluene sulfonic acid (PTSA), hydrochloric acid (HCl) and acetic acid (AcOH), wherein R 1  and R 2  are each selected from H, an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group, or an O-aromatic group; R 7  is an alkyl group, an olefinic group, or an aromatic group; P 1  is a hydroxyl protecting group; P 5  is H or an acid labile protecting group at the 7-O position; R 8  is H, alkyl group, olefinic or aromatic group; and R 9  is: H, alkyl group, olefinic or aromatic or is as defined in the specification.

Claim (Index 25):
A method for use in producing taxane analogs and derivatives thereof, comprising:\n (A) providing a starting compound of formula wherein:\n R 1  and R 2  are each selected from H, an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group, or an O-aromatic group; \n R 7  is an alkyl group, an olefinic group, or an aromatic group; and \n P 1  and P 2  are each hydroxyl protecting groups; \n (B) converting the starting compound into a first taxane analog of the formula \n wherein\n R 1  and R 2  are each selected from H, an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group, and an O-aromatic group; \n R 3  is hydroxyl or OP 1 ; \n R 7 =an alkyl group, an olefinic group, or an aromatic group; \n P 1  is a hydroxyl protecting group.

Metadata:
- Claim Count in Document: 86.0
- Percentile: 99.0
- Lexical Diversity: 2.4186
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14604147', '12954253', '10951555', '15728049', '15220975']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8224636748863351
- 35 USC 102 Novelty (BERT): 0.6101530956811473
- Combined Prediction Score: 0.8012326169658164
- Mean Citation Score: 564.229094
- Max Citation Score: 591.6713
- Similarity Product: 466.5938373377621

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test