PATENT CLAIM ANALYSIS

Application Number: 15761983
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "450000"]

Abstract:
There are provided, inter alia, methods and compositions for diagnosis and treatment of acute myeloid leukemia (AML), secondary acute myeloid leukemia (sAML), and age-related diseases.

Claim (Index 65):
The method of any one of  claims 1 ,  2 ,  19 ,  22 ,  23 ,  40 ,  45 ,  46 ,  59 , and  61 , wherein the splicing modulator is a compound of Formula (I): wherein, X 1  is N, O, or CH 2 ; X 2  is O or C(R 6 )(R 7 ); R 6  and R 7  are independently hydrogen, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, \u2014OR 12 , \u2014OC(O)R 12 , \u2014OC(O)OR 12 , or \u2014OC(O)NR 13 R 14 ; R 1  is hydrogen, \u2014C(O)R 8 , \u2014OC(O)R 8 , \u2014OC(O)OR 8 , or \u2014NHC(O)NHR 8 ; R 2 , R 3 , R 4 , and R 5  are each independently selected from hydrogen, substituted or unsubstituted alkyl, \u2014OR 9 , \u2014OC(O)R 9 , \u2014OC(O)OR 9 , or \u2014OC(O)NR 10 R 11 ; R 8 , R 9 , R 10 , R 11 , R 12 , R 13  and R 14  are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and R 15  is hydrogen, halogen, CF 3 , CCl 3 , CBr 3 , CI 3 , substituted or unsubstituted alkyl.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 1.41667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14342384', '12837409', '14236118', '11528890', '13739788']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7844794329156443
- 35 USC 102 Novelty (BERT): 0.525166090390791
- Combined Prediction Score: 0.7585480986631589
- Mean Citation Score: 266.791298
- Max Citation Score: 290.01474
- Similarity Product: 155.6328844118035

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test