PATENT CLAIM ANALYSIS

Application Number: 16423289
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-10
Patent Classification: ["435", "285100"]

Abstract:
In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.

Claim (Index 1):
A method of creating a cell library of at least 5,000 edited cells using an automated stand-alone multi-module cell editing instrument for nuclease-directed genome editing, comprising the steps of:\n providing live cells in a receptacle configured to receive cells; providing a library of rationally-designed nucleic acids comprising sequences to facilitate nuclease-directed genome edits in the cells in a receptacle configured to receive nucleic acids; growing the live cells in a growth module; transforming the live cells in a transformation module with the library of rationally-designed nucleic acids; providing conditions in a nuclease-directed editing module to allow nuclease-directed editing of nucleic acids in the cells; and using an automated liquid handling system to move liquids from the receptacle configured to receive the cells to the growth module, from the growth module to the transformation module, from the receptacle configured to receive the rationally-designed nucleic acids to the transformation module, and from the transformation module to the nuclease-directed editing module without user intervention, wherein the nuclease-directed genome edits created in the automated stand-alone multi-module cell editing instrument result in a cell library comprising at least 5,000 cells with rationally-designed genome edits.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 100.0
- Lexical Diversity: 1.0
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16412175', '16269671', '16024816', '16269655', '16147865']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.661188532522211
- 35 USC 102 Novelty (BERT): 0.5614861525510841
- Combined Prediction Score: 0.6512182945250983
- Mean Citation Score: 427.313626
- Max Citation Score: 442.8594
- Similarity Product: 405.1979093651533

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test