PATENT CLAIM ANALYSIS

Application Number: 16081654
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-03
Patent Classification: ["514", "211080"]

Abstract:
Described herein are methods of preventing or reducing fibrosis comprising administering CSF1R inhibitors, coating formulations comprising CSF1R inhibitors, coatings comprising CSF1R inhibitors for implantable medical devices, CSF1R inhibitor coated implantable medical devices, as well as corresponding embodiments comprising additional agents.

Claim (Index 1):
A method of preventing or reducing a fibrotic response to an implanted synthetic material in a patient, the method comprising administering to the patient an effective amount of a CSF1R inhibitor selected from the group consisting of a compound of structural formula a compound represented by structural formula a compound represented by structural formula a compound represented by structural formula and AC708, 4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide, (4-cyano-N-(2-cyclohexenyl-4-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)phenyl)-1H-imidazole-2-carboxamide), a compound represented by structural formula ARRY-382, a compound represented by structural formula a 2\u2032-aminoanilide, a 3-amido-4-anilinocinniline, an indoline-2-one, a 2-(alpha-methylbenzylamino)-pyrazine, an arylamide, a 3,4,6-substituted 2-quinolone, a pyrido[2,3-d]pyrimidin-5-one, a 3-amido-4-anilinoquinoline, a pyridyl bisamide, a thiazolyl bisamide, a 1,4-disubstituted-pyrrolo-[3,2-c]-pyridine, a substituted diphenylurea, a 5\u2032-pyrimidine-2,4-diamine, a compound represented by structural formula a compound represented by structural formula anilinoquinazoline, a compound represented by structural formula a compound represented by structural formula DCC-3014, a compound represented by structural formula a compound represented by structural formula a compound represented by structural formula a compound represented by structural formula a compound represented by structural formula a compound represented by structural formula and a compound represented by structural formula

Metadata:
- Claim Count in Document: 13.0
- Percentile: 96.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14776639', '14817084', '14262448', '15831570', '13400382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7077149258757215
- 35 USC 102 Novelty (BERT): 0.511983571986483
- Combined Prediction Score: 0.6881417904867977
- Mean Citation Score: 226.930562
- Max Citation Score: 249.59987
- Similarity Product: 167.76061208752634

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test