PATENT CLAIM ANALYSIS

Application Number: 15554419
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-02
Patent Classification: ["514", "285000"]

Abstract:
Provided herein are compounds and pharmaceutical compositions comprising quinolinones. The quinolinones and compositions thereof are useful as eukaryotic translation initiation factor 4F (eIF4F) complex modulators.

Claim (Index 1):
A compound of Formula (Ia-1), or a pharmaceutically acceptable salt, solvate, tautomer, or N-oxide thereof: wherein A and B are independently a bond, \u2014CH 2 \u2014, \u2014CH 2 CH 2 \u2014, \u2014C(\u2550O)\u2014, \u2014CH\u2550CH\u2014, or \u2014C(\u2550O)NH\u2014; X 1 -X 5  are independently N or CR 1 ; wherein at least one of X 1 -X 5  is N; X 6 -X 8  are independently N or CR 1 ; each R 1  are independently hydrogen, halogen, hydroxyl, alkoxy, cyano, \u2014NR a R b , \u2014C(\u2550O)OR c , alkyl, cycloalkyl, or aryl; wherein the alkyl, alkoxy, cycloalkyl, and aryl are optionally substituted with one or more R d ; R 2  is halogen, hydroxyl, alkoxy, alkyl, or cycloalkyl; wherein the alkyl and cycloalkyl are optionally substituted with one or more R d ; R a  and R b  are independently hydrogen or alkyl; or R 1  and R b  taken together with the nitrogen to which they are attached form a heterocycloalkyl optionally substituted with alkyl; R c  is hydrogen or alkyl; and each R d  is independently alkyl, halogen, hydroxyl, alkoxy, cyano, or \u2014NR a R b .

Metadata:
- Claim Count in Document: 32.0
- Percentile: 90.0
- Lexical Diversity: 1.20833
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15546165', '15329183', '15050045', '14510711', '16062680']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8032927647995278
- 35 USC 102 Novelty (BERT): 0.5388607054331231
- Combined Prediction Score: 0.7768495588628873
- Mean Citation Score: 334.73239
- Max Citation Score: 381.3447
- Similarity Product: 284.2936665341198

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test