PATENT CLAIM ANALYSIS

Application Number: 16142667
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["514", "235800"]

Abstract:
The present disclosure teaches methods for treating and preventing a variety of neurodegenerative conditions and symptoms associated therewith, including Alzheimer's disease (AD) and idiopathic Parkinson's disease (iPD), by utilizing adrenoceptor antagonists. Adrenoceptor antagonists that can be used include β-blockers, such as acebutolol, betaxolol, bisopropolol, bopindolol, carvedilol, metoprolol, oxprenolol, propranolol, and timolol. The present disclosure also teaches methods for diagnosing and monitoring the progression of iPD.

Claim (Index 40):
The method of  claim 38 , wherein the subject has been diagnosed with iPD before the subject exhibits a motor symptom of iPD by a method, comprising:\n performing an assay to measure cardiac uptake of iodine-123-metaiodobenzylguanidine ( 123 I-MIBG) in a subject; and diagnosing the subject as having iPD if the cardiac uptake of  123 I-MIBG is less than that of a subject who does not have iPD.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 97.0
- Lexical Diversity: 1.51786
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14900315', '15451144', '12997767', '15253737', '14098890']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7277076041109485
- 35 USC 102 Novelty (BERT): 0.5792598123057559
- Combined Prediction Score: 0.7128628249304292
- Mean Citation Score: 236.613384
- Max Citation Score: 478.96136
- Similarity Product: 420.60539298423765

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test