PATENT CLAIM ANALYSIS

Application Number: 15966103
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["424", "093710"]

Abstract:
The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same.

Claim (Index 58):
The method of  claim 57 , wherein the bacterium is a  Staphylococcus  sp., an  Enterococcus  sp.,  Bacillus anthracis , a  Lactobacillus  sp., a  Listeria  sp.,  Corynebacterium diphtheria , a  Nocardia  sp., a  Streptococcus  sp., a  Pseudomonas  sp., a  Gardnerella  sp., a  Streptomyces  sp.,  Thermoactinomyces  vulgaris, a  Treponema  sp., a  Campylobacter  sp.,  Pseudomonas aeruginosa , a  Legionella  sp.,  Neisseria gonorrhoeae, Neisseria meningitidis, Flavobacterium meningosepticum, Flavobacterium odoratum , a  Brucella  sp.,  Bordetella pertussis, Bordetella bronchiseptica, Escherichia coli , a  Klebsiella  sp., an  Enterobacter  sp.,  Serratia marcescens, Serratia liquefaciens , an  Edwardsiella  sp.,  Proteus mirabilis, Proteus vulgaris , a  Streptobacillus  sp.,  Rickettsia rickettsii, Chlamydia psittaci, Chlamydia trachomatis, Mycobacterium  ( M .)  tuberculosis, M. intracellulare, M. fortuitum, M. leprae, M. avium, M. bovis, M. africanum, M. kansasii, M. lepraemurium , a  Chlamydia  sp., or a  Rickettsia  sp.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 91.0
- Lexical Diversity: 2.4898
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13459664', '14934256', '13502978', '15003968', '15948303']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7429379990919158
- 35 USC 102 Novelty (BERT): 0.6080886050197181
- Combined Prediction Score: 0.729453059684696
- Mean Citation Score: 519.2540019999999
- Max Citation Score: 542.2982
- Similarity Product: 473.8843017923594

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test