PATENT CLAIM ANALYSIS

Application Number: 15972494
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["536", "004100"]

Abstract:
Described are γ-PNA monomers, methodology for synthesizing them, and methodology for synthesizing PNA oligomers that incorporate them.

Claim (Index 14):
A method comprising: a) contacting a compound of formula X: wherein, P is selected from the group consisting of: 9-fluorenylmethyloxycarbonyl (Fmoc), t-butyloxycarbonyl (Boc), benzyloxycarbonyl (Cbz), benzyl (Bn), tosylate (Tos), allyloxycarbonyl (alloc), trityl (Trt), monomethoxytrityl (MMT) and dimethoxytrityl (DMT); R 5  is selected from the group consisting of hydrogen (H), linear or branched (C 1 -C 8 )alkyl, (C 2 -C 8 )alkenyl, (C 2 -C 8 )alkynyl, (C 1 -C 8 )hydroxylalkyl, (C 3 -C 8 )aryl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )aryl(C 1 -C 6 )alkylene and (C 3 -C 8 )cycloalkyl(C 1 -C 6 )alkylene; one of R 1  and R 2  is \u2014CH 2 \u2014OH and the other of R 1  and R 2  is H with a compound of formula: P 3 \u2014(O\u2014CH 2 \u2014CH 2 \u2014) x OX, wherein X is CH 3 S(O) 2 \u2014, P 3  is methyl, ethyl, or t-butyl; and x is a number from 1 to 10, inclusive, to thereby obtain a compound of formula XI: wherein one of R 11  and R 12  is \u2014CH 2 \u2014O\u2014(CH 2 \u2014CH 2 \u2014O)x-P 3  and the other of R 11  and R 12  is H; and\n b) reducing the carboxylic acid of formula XI to an alcohol to thereby produce a compound of formula

Metadata:
- Claim Count in Document: 25.0
- Percentile: 93.0
- Lexical Diversity: 1.33333
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14110689', '14921755', '14782471', '14782448', '08319411']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6408711107499186
- 35 USC 102 Novelty (BERT): 0.5650988274703641
- Combined Prediction Score: 0.6332938824219632
- Mean Citation Score: 363.37148
- Max Citation Score: 533.13055
- Similarity Product: 347.60554094947577

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test