PATENT CLAIM ANALYSIS

Application Number: 15917421
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["546", "184000"]

Abstract:
Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions comprising the solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.

Claim (Index 77):
A method of treating multiple myeloma, the method comprising administering to a patient dexamethasone in combination with a solid form comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione (pomalidomide); and (b) a coformer; wherein\n the coformer is gallic acid and the solid form has an X-ray powder diffraction (XRPD) pattern comprising peaks at 22.98, 26.16, and 26.90 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is vanillin and the solid form has an XRPD pattern comprising peaks at 13.09, 17.30, and 25.61 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is cyclamic acid and the solid form has an XRPD pattern comprising peaks at 6.42, 7.88, and 15.73 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is D-glucose and the solid form has an XRPD pattern comprising peaks at 17.09, 20.68, and 25.52 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is propyl gallate and the solid form has an XRPD pattern comprising peaks at 7.78, 25.23, and 25.61 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is saccharin and the solid form has an XRPD pattern comprising peaks at 15.98, 19.09, and 25.10 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is sodium lauryl sulfate and the solid form has an XRPD pattern comprising peaks at 2.66, 5.30, and 7.93 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is magnesium bromide and the solid form has an XRPD pattern comprising peaks at 3.23, 28.76, and 29.95 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is malonic acid and the solid form has an XRPD pattern comprising peaks at 12.23, 16.63, and 25.58 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is maltol and the solid form has an XRPD pattern comprising peaks at 16.51, 17.09, and 25.73 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; the coformer is methyl paraben and the solid form has an XRPD pattern comprising peaks at 18.73, 25.69, and 26.70 degrees 2\u03b8\u00b10.2 degrees 2\u03b8; or the coformer is zinc chloride and the solid form has an XRPD pattern comprising peaks at 2.38, 17.17, and 25.71 degrees 2\u03b8\u00b10.2 degrees 2\u03b8.

Metadata:
- Claim Count in Document: 128.0
- Percentile: 90.0
- Lexical Diversity: 1.48387
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15607163', '14780289', '14780495', '15264417', '15849285']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7309011390035148
- 35 USC 102 Novelty (BERT): 0.6023779838451706
- Combined Prediction Score: 0.7180488234876804
- Mean Citation Score: 396.183364
- Max Citation Score: 514.1348
- Similarity Product: 496.0864400775672

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test