PATENT CLAIM ANALYSIS

Application Number: 15934526
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["530", "387100"]

Abstract:
This invention relates to humanized antibodies that selectively bind the 31.1 epitope on the A33 protein differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer, and colon cancer, and diagnostic and therapeutic usages.

Claim (Index 18):
The method of  claim 14 , wherein said antibody or antibody fragment is admixed in a composition with another antibody, label, cytotoxic agent, therapeutic agent, or an immunosuppressive agent, is administered in combination with an antibody, label, cytotoxic agent, therapeutic agent, or an immunosuppressive agent, simultaneously or sequentially, wherein said label is optionally a chemiluminescent label, paramagnetic label, an MRI contrast agent, fluorescent label, bioluminescent label, or radioactive label, wherein said paramagnetic label is optionally paramagnetic label is aluminum, manganese, platinum, oxygen, lanthanum, lutetium, scandium, yttrium, or gallium, wherein the cytotoxic agent is optionally a moiety that inhibits DNA, RNA, or protein synthesis, a radionuclide, ribosomal inhibiting protein,  212 Bi,  131 I,  18 Re,  90 Y, vindesine, methotrexate, adriamycin, cisplatin, pokeweed antiviral protein,  Pseudomonas  exotoxin A, ricin, diphtheria toxin, ricin A chain, or cytotoxic phospholipase enzyme, wherein optionally said therapeutic agent is a lymphokine or growth factor, and/or wherein optionally wherein said immunosuppressive agent is cyclosporine, leflunomide, methotrexate, azothiprine, mercaptopurine, dactinomycin, tacrolimus, or sirolimus.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 90.0
- Lexical Diversity: 1.375
- Patent Class: 530.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14655982', '12751791', '15510545', '14460871', '11715307']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7269322816565723
- 35 USC 102 Novelty (BERT): 0.610772556233406
- Combined Prediction Score: 0.7153163091142556
- Mean Citation Score: 431.43559000000016
- Max Citation Score: 566.4305
- Similarity Product: 498.13482445278777

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test