PATENT CLAIM ANALYSIS

Application Number: 15958218
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
This application is directed generally to minicircle DNA vectors for the vaccination of foot-and-mouth disease (FMD). The transgene expression cassette in the minicircle DNA vector includes: a eukaryotic translation initiation nucleotide sequence, a mutant nucleotide sequence that encodes a foot-and-mouth disease virus (FMDV) capsid polyprotein precursor that contains at least one mutation to eliminate a restriction enzyme recognition site, a nucleotide sequence that encodes a protease that cleaves the MEW capsid polyprotein precursor into plurality of FMDV capsid proteins and a translational regulatory element to regulate the expression of the protease. The minicircle DNA vectors can be transfected directly into the cell of a mammalian host. When transfected into the mammalian host cell, virus-like particles can be produced intrinsically to stimulate the mammalian host's immune system to develop adaptive immunity toward foot-and-mouth disease.

Claim (Index 10):
The method of  claim 6 , wherein the mammal produced the antibody responsive to vaccination with the vector.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 1.75904
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15957376', '14962272', '15259409', '15407982', '14863181']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7820016172983126
- 35 USC 102 Novelty (BERT): 0.6284871541184452
- Combined Prediction Score: 0.766650170980326
- Mean Citation Score: 439.95029000000005
- Max Citation Score: 718.05176
- Similarity Product: 509.9687142228031

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test