PATENT CLAIM ANALYSIS

Application Number: 16163108
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "220000"]

Abstract:
A P2X 4  receptor antagonist such as paroxetine, a diazepinedione derivative having the following formula (IX) is used as an agent for preventing or treating neuropathic pain associated with Guillain-Barré syndrome: wherein R 1  is hydrogen, a C 1-8  alkyl group, or the like; each of R 2  and R 3  is hydrogen, a C 1-8  alkyl group, or the like; each of R 4  and R 5  is hydrogen or the like; and W is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.

Claim (Index 1):
A method of treating neuropathic pain associated with Guillain-Barr\u00e9 syndrome which comprises administrating an effective amount of a compound having the following formula (VIII) or (IX), or a pharmacologically acceptable salt thereof to a patient in need thereof: wherein R 1  is hydrogen, a C 1-8  alkyl group, a C 2-8  alkenyl group, a C 1-8  alkyl group having one to three halogen atoms, or a C 1-3  alkyl group having phenyl; R 2  is hydrogen, a C 1-8  alkyl group, a C 1-8  alkoxy group, a C 1-8  alkyl group having one to three halogen atoms, a C 1-8  alkoxy group having one to three halogen atoms, a halogen atom, hydroxyl, nitro, cyano, amino, a C 1-8  alkylamino group, a C 2-8  dialkylamino group, a C 2-8  acylamino group, a C 2-8  acylamino group having one to three halogen atoms, a C 1-8  alkylsulfonylamino group, carboxyl, a C 2-8  acyl group, an alkoxycarbonyl group comprising a C 1-8  alkoxy moiety, carbamoyl, a C 1-8  alkylthio group, a C 1-8  alkylsulfinyl group, a C 1-8  alkylsulfonyl group, or sulfamoyl; R 3  is hydrogen, a C 1-8  alkyl group, a C 1-8  alkoxy group, a C 1-8  alkyl group having one to three halogen atoms, a C 1-8  alkoxy group having one to three halogen atoms, a halogen atom, hydroxyl, nitro, cyano, amino, carboxyl, a C 2-8  acyl group, or an alkoxycarbonyl group comprising a C 1-8  alkoxy moiety; and each of R 4  and R 5  independently is hydrogen, a C 1-8  alkyl group, or a C 1-8  alkyl group having one to three halogen atoms, wherein R 1  is hydrogen, a C 1-8  alkyl group, a C 2-8  alkenyl group, a C 1-8  alkyl group having one to three halogen atoms, or a C 1-3  alkyl group having phenyl; each of R 2  and R 3  independently is hydrogen, a C 1-8  alkyl group, a C 1-8  alkoxy group, a C 1-8  alkyl group having one to three halogen atoms, a C 1-8  alkoxy group having one to three halogen atoms, a halogen atom, hydroxyl, nitro, cyano, amino, a C 1-8  alkylamino group, a C 2-8  dialkylamino group, a C 2-8  acylamino group, a C 2-8  acylamino group having one to three halogen atoms, a C 1-8  alkylsulfonylamino group, carboxyl, a C 2-8  acyl group, an alkoxycarbonyl group comprising a C 1-8  alkoxy moiety, carbamoyl, a C 1-8  alkylthio group, a C 1-8  alkylsulfinyl group, a C 1-8  alkylsulfonyl group, or sulfamoyl; each of R 4  and R 5  independently is hydrogen, a C 1-8  alkyl group, a C 1-8  alkyl group having one to three halogen atoms, or a C 1-3  alkyl group having phenyl; and W is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 97.0
- Lexical Diversity: 1.71212
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14808609', '13882205', '13807387', '13811909', '13921382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7740625522844035
- 35 USC 102 Novelty (BERT): 0.4950572895565399
- Combined Prediction Score: 0.7461620260116171
- Mean Citation Score: 278.42473800000005
- Max Citation Score: 287.89328
- Similarity Product: 274.8389970446682

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test