PATENT CLAIM ANALYSIS

Application Number: 15767339
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "239200"]

Abstract:
The present invention relates to the treatment of cancer in a subject, wherein cancer cells of said subject overproduce H 2 O 2  and have a level of GSH below 0.5 nmol for 25 000 cells, with aminothiolester compounds or pharmaceutically acceptable salts thereof, in particular with S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, more particularly with 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate. It also relates to a method for selecting a subject suffering from a cancer and who will most likely benefit from a treatment with aminothiolester compounds or pharmaceutically acceptable salts thereof, in particular with S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, more particularly with 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate.

Claim (Index 18):
The method according to  claim 6 , wherein the cancer is chosen from bladder cancer, brain tumors, breast cancer, melanoma, multiple myeloma, leukemia, lymphoma, prostate cancer, cervical cancer, stomach cancer, liver cancer, tongue cancer, ovarian cancer, pancreatic cancer, renal cancer, pleuramesothelomia, osteosarcoma, muscle cancer, lung cancer, kidney cancer, head and neck cancer, colon cancer, blood cancer, cancers of the nervous central system and sarcoma.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 91.0
- Lexical Diversity: 2.10769
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15768468', '13546713', '15495670', '15120476', '12094739']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7393916857586372
- 35 USC 102 Novelty (BERT): 0.6248210778924594
- Combined Prediction Score: 0.7279346249720194
- Mean Citation Score: 297.077218
- Max Citation Score: 675.13763
- Similarity Product: 492.0436439380848

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test