PATENT CLAIM ANALYSIS

Application Number: 15760878
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["424", "186100"]

Abstract:
Provided are polypeptides derived from the coronaviruses (CoVs) Spike protein (S) characterized by high affinity and specificity the S receptor and its neutralizing antibodies. Further provided are compositions and vaccines, and vaccine-based therapies targeting CoVs, and SARS and MERS viruses in particular.

Claim (Index 42):
A polypeptide comprising an amino acid sequence of at least one reconstituted Receptor Binding Motif (RBM) of a viral Spike protein or of any fragment thereof, wherein said reconstituted RBM comprises at least one linker and at least one fragment of the native RBM, said native RBM is a 30 to 200 amino acid sequence comprised within the Receptor Binding Domain (RBD) of said Spike protein forming a binding interface that interacts with the viral receptor, wherein said native RBM forms an extended 30 to 100 or more amino acid excursion juxtaposed along the edge of the core of the RBD and tacked to said core via a tacking segment, and wherein at least one of said linker/s replaces or is added to at least one of: said tacking segment, any part or amino acid residue/s thereof and any RBM fragment or amino acid residue/s thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.35135
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15306617', '10997201', '14375083', '15553466', '14717760']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7890844053244621
- 35 USC 102 Novelty (BERT): 0.5605229240416502
- Combined Prediction Score: 0.7662282571961809
- Mean Citation Score: 451.928406
- Max Citation Score: 490.51212
- Similarity Product: 331.63800026299947

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test