PATENT CLAIM ANALYSIS

Application Number: 16230957
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["514", "563000"]

Abstract:
The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

Claim (Index 4):
Process for preparing a compound of the formula (I) according to  claim 1 , characterized in that a carboxylic acid of the formula (II) in which R 8A , R 8B , R 9  and R 10  have the meanings given in  claim 1 , is coupled in an inert solvent with the aid of a condensing agent or via the intermediate of the corresponding carbonyl chloride in the presence of a base with an amine of the formula (III) in which L, R 1 , R 2 , R 3 , R 4A , R 4B , R 5 , R 6  and R 7  have the meanings given in  claim 1 and T 1  represents (C 1 -C 4 )-alkyl or benzyl, to give a carboxamide of the formula (IV) in which L, R 1 , R 2 , R 3 , R 4A , R 4B , R 5 , R 6 , R 7 , R 8A , R 8B , R 9 , R 10  and T 1  have the meanings given above, and the ester radical T 1  is then removed by basic or acidic solvolysis or, in the case that T 1  represents benzyl, also by hydrogenolysis to give the carboxylic acid of the formula (I) and the compounds of the formula (I) are optionally separated by methods known to the person skilled in the art into their enantiomers and/or diastereomers and/or reacted with the appropriate (i) solvents and/or (ii) bases to give their solvates, salts and/or solvates of the salts.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 98.0
- Lexical Diversity: 1.7027
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14402232', '13312320', '15027519', '13748043', '14045630']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8197298597390815
- 35 USC 102 Novelty (BERT): 0.5748548280625059
- Combined Prediction Score: 0.795242356571424
- Mean Citation Score: 405.830476
- Max Citation Score: 460.7802400000001
- Similarity Product: 430.9468819160938

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test