PATENT CLAIM ANALYSIS

Application Number: 16149025
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-03
Patent Classification: ["435", "188000"]

Abstract:
The present disclosure provides systems and methods for increasing production of an alkaloid product through the epimerization of a (S)-1-benzylisoquinoline alkaloid to a (R)-1-benyzlisoquinoline alkaloid via an engineered epimerase in an engineered host cell. A (S)-1-benzylisoquinoline alkaloid is contacted with said engineered epimerase. Contacting said (S)-1-benzylisoquinoline alkaloid with said engineered epimerase converts said (S)-1-benzylisoquinoline alkaloid to said (R)-1-benzylisoquinoline alkaloid.

Claim (Index 27):
The method of  claim 21 , wherein said oxidase component comprises a sequence that is encoded by a DNA sequence which comprises one or more codon substitutions, relative to a wildtype sequence, at a codon position which corresponds to an amino acid position in SEQ ID NO. 17 selected from the group consisting of position 75, 160, 191, 256, 359, 366, and 500.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 97.0
- Lexical Diversity: 2.05128
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15031618', '14211611', '15360763', '14614484', '14961662']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6662133367771593
- 35 USC 102 Novelty (BERT): 0.5274424324782307
- Combined Prediction Score: 0.6523362463472665
- Mean Citation Score: 346.805698
- Max Citation Score: 403.10944
- Similarity Product: 295.8658572606468

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test