PATENT CLAIM ANALYSIS

Application Number: 15909240
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "547000"]

Abstract:
A method of treatment of mild to moderate non-penetrating closed traumatic brain injury and mild to moderate TBI due to surgical intervention using 3-hydroxybutyate glycerides is disclosed.

Claim (Index 14):
A method of prophylactically treating a subject that is going into a situation that is likely to result in a mild to moderate non-penetrating closed Traumatic Brain Injury (TBI) or is having a surgical intervention involving potential injury to brain cells comprising:\n administering at least one glyceryl 3-hydroxybutyrate ester to said subject, said administering being an amount of at least one glyceryl (3-hydroxybutyrate) in conjunction with maintaining a normal diet, said normal diet having greater than 10% carbohydrate and greater than 15% protein; whereby if the subject does suffer a mild to moderate non-penetrating closed TBI or a mild to moderate TBI secondary to said surgical intervention within 12 hours after said administration, said administration results in an elevated ketone body blood level at the time of said TBI taking place, whereby the acute adverse effects of said TBI are minimized; wherein said amount of said glyceryl 3-hydroxybutyrate ester that is administered is in the range of 0.166 g/kg to 1.0 g/kg when glyceryl tris(3-hydroxybutyrate) is being administered or stoichiometrically equivalent amounts thereof based on the 3-hydroxybutyrate moiety when other glyceryl 3-hydroxybutyrate esters are being administered.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 1.21739
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15404396', '13054053', '13358257', '12064850', '12304341']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7015760556316505
- 35 USC 102 Novelty (BERT): 0.6172027799443925
- Combined Prediction Score: 0.6931387280629246
- Mean Citation Score: 310.443414
- Max Citation Score: 569.4829
- Similarity Product: 488.2598729500175

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test