PATENT CLAIM ANALYSIS

Application Number: 15977933
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["800", "018000"]

Abstract:
The present invention provides for inhibition or blockade of immunomodulatory cell receptors to facilitate improved or complete reconstitution of a human immune system in laboratory animals, improve animal health, and improve animal longevity. Thus, the invention relates generally to compositions and methods of generating and using transgenic non-human animals that are engrafted with a human hematopoietic system involving anti-CCR 5  agents. In various embodiments, the human hematopoietic system engrafted transgenic non-human animals of the invention are useful as systems for the in vivo evaluation of the growth and differentiation of hematopoietic and immune cells, immune responses, vaccines and vaccination regimens, and human pathogens and production and collection of immune mediators, including human antibodies.

Claim (Index 18):
The method of  claim 15 , wherein the immunocompromised transgenic animal is a mouse.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 93.0
- Lexical Diversity: 1.74648
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15223879', '13847636', '12942666', '14420318', '15192903']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6158514874126713
- 35 USC 102 Novelty (BERT): 0.5300091268904167
- Combined Prediction Score: 0.6072672513604458
- Mean Citation Score: 363.076602
- Max Citation Score: 386.69727
- Similarity Product: 281.431501212852

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test