PATENT CLAIM ANALYSIS

Application Number: 16126300
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-02
Patent Classification: ["530", "321000"]

Abstract:
The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.

Claim (Index 25):
A method of antagonizing the interaction between a p53 protein and a HDM2 protein, between a p53 protein and a HDMX protein, or a combination thereof, in a subject comprising administering to the subject a therapeutically-effective amount of a peptidomimetic macrocycle, wherein the peptidomimetic macrocycle comprises an amino acid sequence which is at least 60% identical to an amino acid sequence selected from the group consisting of: SEQ ID NO. 254, SEQ ID NO. 289, SEQ ID NO. 290, SEQ ID NO. 374, SEQ ID NO. 375, SEQ ID NO. 507, SEQ ID NO. 533, SEQ ID NO. 587, SEQ ID NO. 605, SEQ ID NO. 624, SEQ ID NO. 642, SEQ ID NO. 699, SEQ ID NO. 702, SEQ ID NO. 703, SEQ ID NO. 704, SEQ ID NO. 714, SEQ ID NO. 734, and SEQ ID NO. 742.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.11765
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13816880', '15135098', '14498063', '13767852', '15229517']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6475441413620024
- 35 USC 102 Novelty (BERT): 0.6707568636059051
- Combined Prediction Score: 0.6498654135863927
- Mean Citation Score: 711.03794
- Max Citation Score: 775.3979
- Similarity Product: 626.9236156671584

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test