PATENT CLAIM ANALYSIS

Application Number: 16015227
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "395000"]

Abstract:
The present invention belongs to the pharmaceutical field, and relates to a preparation method for a series of benzimidazole derivatives, their pharmaceutical salts and pharmaceutically acceptable prodrugs, a pharmaceutical composition containing the derivatives, and the uses of the derivatives and pharmaceutical composition in the preparation of antigout drugs and in the treatment of related diseases.

Claim (Index 5):
A method of preparing the benzimidazole derivative of  claim 1 , said method comprising the steps of:\n (1) Reacting a compound of Formula (II) with a compound of Formula (III) in the presence of a base to form a compound of Formula (IV); (2) Reacting said compound of Formula (IV) with a reducing agent to form a compound of Formula (V); (3) Reacting said compound of Formula compound (V) with thiophosgene to form a compound of Formula (VI); (4) Reacting said compound of Formula (VI) with a compound of Formula (VII) under basic condition to form a compound of Formula (VIII); (5) Hydrolyzing said compound of Formula (VIII) under basic condition to form a compound of Formula (IX); (6) Reacting said compound of Formula (IX) with a base to form a compound of Formula (I), wherein M is a pharmaceutically acceptable cation; or reacting said compound of Formula (IX) with a chlorinating reagent, followed by an alcohol or amine to form a compound of Formula (I), wherein M is C 1-6  alkyl, amino or ester,

Metadata:
- Claim Count in Document: 16.0
- Percentile: 94.0
- Lexical Diversity: 1.76471
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14777317', '15492306', '14576683', '14210888', '14911000']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7828773906501861
- 35 USC 102 Novelty (BERT): 0.5283518056940183
- Combined Prediction Score: 0.7574248321545693
- Mean Citation Score: 317.392386
- Max Citation Score: 349.67477
- Similarity Product: 234.365637435562

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test