PATENT CLAIM ANALYSIS

Application Number: 16026397
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["546", "323000"]

Abstract:
The present invention relates to compounds comprising a protecting group moiety-tag moiety conjugate, a method of purification and monoconjugates obtained from such method of purification.

Claim (Index 20):
A method of purification, comprising the steps of:\n (i) providing a mixture comprising a multitude of conjugates selected from the group consisting of formula (III) and formula (IIIa) which differ by their value for x, where the formulas (III) and (IIIa) are:\n (T-PG-X 1 -L-X 2 ) x -PM\u2003\u2003(III); and \n (T-PG-L 2 -L 1 ) x -PM\u2003\u2003(IIIa); \n wherein:\n each T is, independently of each other, a tag moiety; and \n each PG is, independently of each other, a protecting group moiety; \n X 1  and X 2  are each, independently of each other, a linkage; \n L and L 2  are each, independently of each other, a chemical bond or a spacer moiety; \n L 1  is a reversible prodrug linker moiety; \n each x is, independently of each other, an integer from 1-20; and \n each PM is, independently from each other, a moiety having a molecular weight of at least 1 kDa; \n (ii) subjecting the mixture of step (i) to a purification method suitable for the tag moiety T; and (iii) isolating a fraction that comprises compounds of formula (III) or (IIIa) in which at least 80% of all compounds of formula (III) or (IIIa) have the same value for x.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 1.17391
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15027976', '14435350', '12990101', '14238437', '14650175']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7929037818389609
- 35 USC 102 Novelty (BERT): 0.5923935599165712
- Combined Prediction Score: 0.772852759646722
- Mean Citation Score: 374.628792
- Max Citation Score: 520.1981
- Similarity Product: 469.8687988859176

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test