PATENT CLAIM ANALYSIS

Application Number: 16294971
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["424", "497000"]

Abstract:
A method for temporarily relieving sinus congestion and pressure comprising administering to a human a dose of a multi-particle pulsatile oral dosage form with an immediate release form and a plurality of delayed release particles. The immediate release form contains about 10 mg phenylephrine hydrochloride. The delayed release form contains a core with coatings including a phenylephrine coating containing about 10 mg phenylephrine hydrochloride and a pH sensitive coating.

Claim (Index 12):
A method for temporarily relieving sinus congestion and pressure comprising administering to a human a dose of a multi-particle pulsatile oral dosage form comprising:\n a. an immediate release form comprising from about 10 mg to about 20 mg phenylephrine or a pharmaceutically acceptable salt thereof; and b. a plurality of delayed release particles; wherein each delayed release particle comprises:\n i. a core; \n ii. a phenylephrine coating comprising phenylephrine hydrochloride; \n iii. a pH sensitive coating wherein the pH sensitive coating comprises an enteric coating;\n wherein the pH sensitive coating is from 10 \u03bcm to about 80 \u03bcm thick; \n wherein the plurality of delayed release particles comprise from about 7 mg to about 15 mg phenylephrine hydrochloride; \n wherein the pulsatile dosage form comprises a C max2  and an AUC 4-8  wherein an upper bound of a 90% confidence interval for a ratio of means for the C max2  and the AUC 4-8  of the pulsatile dosage form relative to two sequential doses of an immediate release phenylephrine taken four hours apart is at least 85%.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 99.0
- Lexical Diversity: 1.67442
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15460459', '14857848', '15701669', '11756881', '14661639']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7465008097674023
- 35 USC 102 Novelty (BERT): 0.5918635910530882
- Combined Prediction Score: 0.7310370878959709
- Mean Citation Score: 376.671322
- Max Citation Score: 506.72052
- Similarity Product: 464.37448842318537

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test