PATENT CLAIM ANALYSIS

Application Number: 15925544
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "094300"]

Abstract:
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.

Claim (Index 170):
The single molecule DNA-targeting RNA, or the nucleic acid comprising a nucleotide sequence encoding said single molecule DNA-targeting RNA, of  claim 169 , wherein the one or more modified nucleotides are modified at the ribose, phosphate, and/or base moiety.

Metadata:
- Claim Count in Document: 31.0
- Percentile: 90.0
- Lexical Diversity: 2.25424
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15435233', '15138604', '13842859', '14685504', '14942782']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6501897147570638
- 35 USC 102 Novelty (BERT): 0.7062963188920576
- Combined Prediction Score: 0.6558003751705632
- Mean Citation Score: 757.7960860000003
- Max Citation Score: 783.197
- Similarity Product: 687.9750181037782

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test