PATENT CLAIM ANALYSIS

Application Number: 15998791
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["546", "212000"]

Abstract:
The present invention relates to a novel 2,3,5-substituted thiophene compound having inhibitory activity against kinases, an anticancer agent including the compound as an active ingredient, and a method for preparing the compound.

Claim (Index 1):
A compound selected from the group consisting of a 2,3,5-substituted thiophene compound of Formula 1, a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, and an isomer thereof: wherein:\n Z is O, S, or NH, \n Y is a C 1-6  alkylene group; a C 2-6  alkenylene group; or a C 2-6  alkynylene group, \n A is a C 3-8  heterocycloalkyl group comprising one or two N atoms; a C 6-12  aryl group; or a C 3-12  heteroaryl group comprising one or two heteroatoms selected from N and S, \n R 1  is selected from the group consisting of halo, nitro, cyano, C 1-6  alkyl, C 1-6  haloalkyl, \u2014(CH 2 ) m \u2014C 1-6  alkoxy wherein m is an integer from 1 to 6, \u2014C(O)O\u2014C 1-6  alkyl, \u2014S(O) 2 \u2014C 1-6  alkyl, C 3-8  cycloalkyl, C 3-8  heterocycloalkyl comprising one or two heteroatoms independently selected from O and N, C 6-12  aryl, and C 3-8  heteroaryl comprising one or two heteroatoms independently selected from O and N, the number of substitutions of the substituent R 1  is 0 to 3, and when the substituent R 1  is heterocycloalkyl, aryl, or heteroaryl, the substituent R 1  is optionally unsubstituted or substituted with halo, C 1-6  alkyl, C 1-6  alkyl-C(O)\u2014 or C 1-6  alkyl-S(O) 2 \u2014, \n R 2  and R 3  are the same as or different from each other, and are each independently a hydrogen atom; a halogen atom; a hydroxyl group; a C 1-6  alkyl group; a C 3-8  cycloalkyl group; a C 1-6  hydroxyalkyl group; a C 1-6  haloalkyl group; a C 1-6  alkoxy group; a \u2014C(O)\u2014C 1-6  alkyl group; a \u2014S(O) 2 \u2014C 1-6  alkyl group; or \u2014NR 4 R 5 , \n R 4  and R 5  are the same as or different from each other, and are each independently a hydrogen atom; a C 1-6  alkyl group; a C 3-8  cycloalkyl group; a C 3-8  heterocycloalkyl group comprising one or two heteroatoms selected from O and N; or a C 6-12  aryl group, and \n n is an integer from 1 to 3.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.2069
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15370631', '14153891', '13834316', '13980182', '13080762']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7781588019132298
- 35 USC 102 Novelty (BERT): 0.4956224190227472
- Combined Prediction Score: 0.7499051636241816
- Mean Citation Score: 258.022286
- Max Citation Score: 262.91245
- Similarity Product: 201.51085821092124

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test