PATENT CLAIM ANALYSIS

Application Number: 16146894
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["514", "275000"]

Abstract:
The invention provides compounds of Formula I, and methods of treating or preventing a bacterial infection in a subject using a compound of Formula I. The invention also provides the use of a compound of Formula I in the manufacture of a medicament for the treatment of a bacterial infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a bacterial infection in a subject and to a medical device comprising the composition of the invention.

Claim (Index 49):
A compound selected from the group consisting of:\n NCL178 4,6-bis(2-((E)-1-(4-chlorophenyl)ethylidene)hydrazinyl)pyrimidine NCL179 4,6-bis(2-((E)-4-chlorobenzylidene)hydrazinyl)pyrimidin-2-amine NCL180 (2Z,2\u2032Z)-2,2\u2032-(pyrimidine-4,6-diylbis(hydrazin-2-yl-1-ylidene))bis(2-(4-chlorophenyl)ethan-1-ol) NCL 181 4,6-bis(2-((E)-4-chlorobenzylidene)hydrazinyl)pyrimidine NCL183 N4,N6-bis(1-phenylethyl)pyrimidine-4,6-diamine NCL184 N4,N6-bis(1-phenylethyl)pyrimidine-2,4,6-triamine NCL185 4,6-bis(2-((E)-1-(4-chlorophenyl)ethylidene)hydrazinyl)pyrimidinehydrochloride NCL 187 4,6-bis(2-((E)-4-chlorobenzylidene)hydrazinyl)pyrimidinehydrochloride NCL189 (2Z,2\u2032Z)-2,2\u2032-(pyrimidine-4,6-diylbis(hydrazin-2-yl-1-ylidene))bis(2-(4-chlorophenyl)ethan-1-ol)hydrochloride NCL193 4,6-bis(2-((E)-4-bromobenzylidene)hydrazinyl)pyrimidin-2-amine NCL194 N\u2032,N\u2032\u2033-(2-aminopyrimidine-4,6-diyl)di(benzohydrazide) NCL195 4,6-bis(2-((E)-4-methylbenzylidene)hydrazinyl)pyrimidin-2-amine NCL 196 4,4\u2032-((1E,1\u2032E)-((2-aminopyrimidine-4,6-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL197 3,3\u2032-((1E,1\u2032E)-((2-aminopyrimidine-4,6-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL198 4,6-bis(2-((E)-4-(tert-butyl)benzylidene)hydrazinyl)pyrimidin-2-aminedihydrochloride NCL199 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-amine NCL200 4,6-bis(2-((E)-4-(tert-butyl)benzylidene)hydrazinyl)pyrimidin-2-amine NCL201 4,4\u2032-((1E,1\u2032E)-((2-aminopyrimidine-4,6-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))bis(N,N-dimethylaniline) NCL202 2,2\u2032-((1E,1\u2032E)-((2-aminopyrimidine-4,6-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL203 4,6-bis(2-((E)-cyclohexylmethylene)hydrazinyl)pyrimidin-2-aminedihydrochloride NCL204 4,6-bis(2-((E)-1-(4-chlorophenyl)ethylidene)hydrazinyl)pyrimidin-2-amine NCL205 4,6-bis(2-((E)-2-chlorobenzylidene)hydrazinyl)pyrimidin-2-amine NCL206 4,6-bis(2-((E)-4-methylbenzylidene)hydrazinyl)-1,3,5-triazin-2-amine NCL207 2,2\u2032-((1E,1\u2032E)-((6-amino-1,3,5-triazine-2,4-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL208 4,6-bis(2-((E)-1-(4-chlorophenyl)ethylidene)hydrazinyl)-1,3,5-triazin-2-amine NCL209 3,3\u2032-((1E,1\u2032E)-((6-amino-1,3,5-triazine-2,4-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL210 4,6-bis(2-((E)-4-(trifluoromethyl)benzylidene)hydrazinyl)-1,3,5-triazin-2-amine NCL211 4,4\u2032-((1E,1\u2032E)-((6-amino-1,3,5-triazine-2,4-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol NCL212 4,6-bis(2-((E)-4-bromobenzylidene)hydrazinyl)-1,3,5-triazin-2-amine NCL213 4,6-bis(2-((E)-cyclohexylmethylene)hydrazinyl)-1,3,5-triazin-2-amine NCL218 4-((E)-(2-(2-amino-6-(2-((E)-4-((diethoxyphosphoryl)oxy)benzylidene)hydrazinyl)pyrimidin-4-yl)hydrazono)methyl)phenyldiethylphosphate NCL220 4,6-bis(2-((E)-4-fluorobenzylidene)hydrazinyl)pyrimidin-2-amine NCL221 4,6-bis(2-((E)-4-(trifluoromethyl)benzylidene)hydrazinyl)pyrimidin-2-amine NCL222 4,6-bis(2-((E)-3,4-difluorobenzylidene)hydrazinyl)pyrimidin-2-amine NCL223 N,N\u2032-(((1E,1\u2032E)-((2-aminopyrimidine-4,6-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))bis(4,1-phenylene))diacetamide NCL230 4,6-bis(2-((E)-4-methoxybenzylidene)hydrazinyl)pyrimidin-2-amine

Metadata:
- Claim Count in Document: 5.0
- Percentile: 97.0
- Lexical Diversity: 2.43243
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14888306', '14888289', '15363523', '15508266', '12973078']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7834311627769865
- 35 USC 102 Novelty (BERT): 0.7049355331567612
- Combined Prediction Score: 0.775581599814964
- Mean Citation Score: 434.21039400000006
- Max Citation Score: 808.9924
- Similarity Product: 706.6463662453174

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test