PATENT CLAIM ANALYSIS

Application Number: 15767116
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-03
Patent Classification: ["424", "009510"]

Abstract:
Compositions and methods for administration of local anesthetics that are delivered by a single injection and enable repeated on-demand or high influx analgesia over extended periods have been developed. Pharmaceutical compositions including an effective amount of one or more sodium channel blockers including site 1 sodium channel blockers, optionally one or more alpha-2-adrenergic agonists, which are optionally encapsulated in liposomes, particles or microbubbles, and one or more triggerable elements are provided. The triggerable elements allow delivery of the encapsulated anesthetic drugs when an appropriate triggering stimuli are applied. Exemplary triggering agents or stimuli include near-infrared irradiation, UV- and visible light, ultrasound and magnetic field. In one embodiment, ultrasound is used to trigger a burst of microbubbles to enhance penetration of local anesthetic.

Claim (Index 28):
The method of  claim 27  further comprising removing the triggering source to prevent further release once the level of pain relief is achieved.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 91.0
- Lexical Diversity: 1.55814
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12993759', '13515764', '13581274', '12993622', '14904385']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6576386133722373
- 35 USC 102 Novelty (BERT): 0.5308634668783991
- Combined Prediction Score: 0.6449610987228536
- Mean Citation Score: 233.504918
- Max Citation Score: 248.979
- Similarity Product: 115.3031732132435

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test