PATENT CLAIM ANALYSIS

Application Number: 16022481
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "04400A"]

Abstract:
Means and methods for therapeutic intervention of mitochondrial disorders or diseases, and in particular to a method for the treatment, prevention and/or amelioration of a disorder or disease correlated with mitochondrial stress or dysfunction, a mitochondrial disorder or disease, or a disorder or disease characterized by OPA1 alterations are disclosed. Thereby, a pharmaceutically active amount of a compound capable of modulating the activity of OMA1 and/or an oligomeric complex comprising OMA1 is administered to a patient in need of medical intervention. Methods of screening for a compound capable of modulating the activity of OMA1 and/or an oligomeric complex comprising OMA1 are disclosed. Methods for determining the susceptibility for, predisposition for, or the presence of such a disorder or disease and whether a person in need will benefit from the therapeutic intervention, i.e. personalized medicine are also disclosed.

Claim (Index 17):
A method for selectively treating a subject in need of medical intervention comprising:\n (a) obtaining a sample from said subject, and (b) performing a reaction to detect an activity or a level of OMA1 or an oligomeric complex comprising OMA1 in said sample, and (c) selectively administering to said subject a pharmaceutically active amount of a compound that modulates said activity or said level of OMA1 or the oligomeric complex comprising OMA1, whereby said method provides useful for treating said subject notwithstanding an underlying clinical diagnosis of a disease or a disorder.

Metadata:
- Claim Count in Document: 55.0
- Percentile: 94.0
- Lexical Diversity: 2.17391
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13402933', '12094787', '10290461', '15158689', '14530049']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7278075464047569
- 35 USC 102 Novelty (BERT): 0.5165585858100924
- Combined Prediction Score: 0.7066826503452905
- Mean Citation Score: 207.559738
- Max Citation Score: 268.74496
- Similarity Product: 159.05299967559813

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test