PATENT CLAIM ANALYSIS

Application Number: 15872331
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "227800"]

Abstract:
The present invention is directed to compositions and methods for modulating c-Rel-dependent cytokine production without materially altering the level of expression of NFκB and/or the amount of IκB. The present invention is also directed to screening for modulators of c-Rel activity as determined by assaying for altered subcellular localization of c-Rel but where the level of expression of NFκB and/or the amount of IκB is materially unaltered.

Claim (Index 43):
The method of  claim 42 , wherein the neurological disease, disorder or condition is selected from the group consisting of multiple sclerosis, AIDS dementia complex, acute transverse myelitis, Huntington's Chorea, senile chorea, Parkinson's disease, progressive supranucleo palsy, spinal ataxia, Friedreich's ataxia, amyotrophic lateral sclerosis, infantile spinal muscular atrophy, juvenile spinal muscular atrophy, Down's Syndrome in middle age; diffuse Lewy body disease, senile dementia of Lewy body type, Wernicke-Korsakoff syndrome, Creutzfeldt-Jakob disease; subacute sclerosing panencephalitis, Hallerrorden-Spatz disease, and dementia pugilistica.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.68293
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14542453', '13810668', '14449599', '14166681', '11478073']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.714795702953491
- 35 USC 102 Novelty (BERT): 0.5435572331869473
- Combined Prediction Score: 0.6976718559768367
- Mean Citation Score: 220.6252
- Max Citation Score: 410.61975
- Similarity Product: 233.46289684277767

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test