PATENT CLAIM ANALYSIS

Application Number: 15971822
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["600", "235000"]

Abstract:
The disclosure concerns a medical kit arranged with componentry for fluorescein sodium (FNa)-based diagnosis and trichloroacetic acid (TCA)-based treatment of neoplastic tissue, and related methods for utilizing aspects of the medical kit.

Claim (Index 20):
A method for practicing the diagnosis and treatment of tissue exhibiting intraepithelial neoplasia, the method comprising:\n providing a medical kit comprising: a speculum, a light source, and a plurality of pre-filled containers, wherein the plurality of pre-filled containers comprises at least:\n a first containing saline solution, a second containing acetic acid, and a third containing fluorescein sodium; \n diagnosing the cervical intraepithelial neoplasia, said diagnosing comprising:\n inserting the speculum into a patient's vagina to expose the entire cervix of the patient; \n rinsing the patient's cervix with the saline solution contained in the first of the pre-filled containers to remove discharge and detritus; \n using the light source and colposcope: visually identifying abnormal cervical vasculature with green light from the light source; \n applying the acetic acid contained in the second of the pre-filled containers to the patient's cervix for staining abnormal tissue acetowhite; \n applying aqueous iodine solution to the patient's cervix for staining normal tissue brown; \n using the colposcope: visualizing the patient's cervix and identifying brown staining of benign tissue in conjunction with acetowhite staining of abnormal tissue, and recording findings; \n rinsing the patient's cervix with the saline solution; \n applying the fluorescein sodium contained in the third of the pre-filled containers to the patient's cervix; \n visualizing fluorescent green staining of malignant and premalignant tissue using blue light of the light source, and recoding findings; \n rinsing the patient's cervix with the saline solution; \n performing one or more cervical biopsies and endocervical curettage if desired to compare with cytological results or proceeding with treatment based on the findings; and \n if biopsies are performed and bleeding occurs at biopsy sites, obtaining hemostasis by applying silver nitrate to affected areas; and \n treating the cervical tissue indicating intraepithelial neoplasia based on the findings, the treating comprising:\n applying trichloro acetic acid solution to an entirety of the patient's cervix; \n using a first swab: collecting an amount of the applied trichloroacetic acid and further spreading the trichloroacetic acid solution to the squamocolumnar junction and the endocervix; \n using a second swab: removing excess trichloroacetic acid solution to prevent incidental chemical cauterization of the vaginal wall; \n removing the speculum from the vagina; and \n repeating the diagnosing and treating until there are no findings of neoplastic tissue.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 93.0
- Lexical Diversity: 1.25
- Patent Class: 600.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10240367', '14004907', '11540334', '13320558', '12368647']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4141996638085628
- 35 USC 102 Novelty (BERT): 0.4797368977234617
- Combined Prediction Score: 0.4207533872000527
- Mean Citation Score: 187.104256
- Max Citation Score: 193.67422
- Similarity Product: 141.18695414330483

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test