PATENT CLAIM ANALYSIS

Application Number: 15934304
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "001850"]

Abstract:
A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a surface of the non-cancerous tissue, provided that the administration is carried out after a waiting period that follows administration of a compound including a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue, and, further provided that the binding sites have an affinity for both the agent and the compound.

Claim (Index 18):
A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with prostate cancer, the method comprising:\n administering to the patient a compound comprising a radionuclide and a recognition moiety for Prostate Specific Membrane Antigen (\u201cPSMA\u201d), the compound binding to both cancerous prostate tissue and the non-cancerous tissue, and, after a waiting period of 1 hour to 60 hours, administering an agent in an amount sufficient to cause a displacement of the bound compound from the binding sites in the non-cancerous tissue by binding of the agent thereto while retaining the radionuclide in the cancerous tissue thereby reducing the exposure of the non-cancerous tissue to the radionuclide as determined by a relative reduction in the intensity of a single-photon emission computed tomography (SPECT) image of the non-cancerous tissue after administration of the agent compared to a SPECT image of the non-cancerous tissue after compound administration but before agent administration; wherein:\n the binding sites are attached to both the agent and the compound, and \n the agent has a different chemical structure from the compound, or the agent has the same chemical structure as the compound absent the radionuclide, and \n the agent comprises a recognition moiety for PSMA.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.97917
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14846252', '15233096', '11936659', '15630808', '15794220']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6295643423625101
- 35 USC 102 Novelty (BERT): 0.6301008212375528
- Combined Prediction Score: 0.6296179902500144
- Mean Citation Score: 260.39185200000003
- Max Citation Score: 553.8699
- Similarity Product: 551.0378280256391

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test