PATENT CLAIM ANALYSIS

Application Number: 16117674
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["544", "405000"]

Abstract:
The present invention relates to compounds of formula I: in which m, Y 1 , Y 2 , Y 3 , R 1 , R 2a , R 2b , R 3a , R 3b , R 4a , R 4b , R 5a  and R 5b  are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Claim (Index 1):
A compound of formula Ic: in which: n is selected from 1, 2, 3, 4 and 5; Y 1  is selected from CH and N; Y 2  is selected from CR 6  and N; R 3a  is selected from C 1-4 alkyl, C 1-4 alkoxy, amino, hydroxy, C 3-8 cycloalkyl and C 1-4 alkyl-amino; R 4a  is selected from hydrogen, C 1-4 alkyl, C 1-4 alkoxy, amino, hydroxy, C 3-8 cycloalkyl and C 1-4 alkyl-amino; R 6  is selected from hydrogen, halo and methyl; R 9  is selected from halo, amino, hydroxy, N 3 , C 1-4 alkyl, halo-substituted-C 1-4 alkyl, C 1-4 alkoxy, \u2014C(O)OR 10  and \u2014NHC(O)R 10 ; R 10  is selected from hydrogen, phenyl and naphthyl; wherein said phenyl of R 13  is unsubstituted or substituted with methoxy; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.84746
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15110498', '15726189', '15110504', '15899821', '15736989']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8063711424710299
- 35 USC 102 Novelty (BERT): 0.5146138478814976
- Combined Prediction Score: 0.7771954130120767
- Mean Citation Score: 309.015682
- Max Citation Score: 317.95245
- Similarity Product: 244.05510789434013

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test