PATENT CLAIM ANALYSIS

Application Number: 15969686
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["435", "325000"]

Abstract:
High efficiency methods for producing retinal pigment epithelial cells from induced pluripotent stem cells (iPSCs) are disclosed herein. The iPSCs are produced from somatic cells, including retinal pigment epithelial (RPE) cells, such as fetal RPE stem cells. In some embodiments, the iPSC include a tyrosinase promoter operably linked to a marker. Methods are disclosed for using the RPE cells, such as for treatment. Methods for screening for agents that affect RPE differentiation are also disclosed.

Claim (Index 10):
The method of  claim 1 , wherein the first medium comprises 50 ng/ml of Dickkopf-related protein 1 (DKK1).

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 1.72549
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15028618', '15143141', '14712633', '13055708', '12450943']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6127779093811239
- 35 USC 102 Novelty (BERT): 0.5362002943449068
- Combined Prediction Score: 0.6051201478775021
- Mean Citation Score: 315.629002
- Max Citation Score: 353.2595
- Similarity Product: 206.8229941939116

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test