PATENT CLAIM ANALYSIS

Application Number: 15752839
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["546", "193000"]

Abstract:
The invention generally relates to cyclic compounds and, more particularly, to a compound represented by Structural Formula I: or a pharmaceutically acceptable salt thereof and pharmaceutical compositions comprising the multicyclic compounds. The invention also relates to a method for treating a disease or disorder selected from cancer (e.g., lymphoma, such as mantle cell lymphoma), a neurodegenerative disease, an inflammatory diseases or an immune system disease (e.g., a T-Cell mediated autoimmune disease) in a subject in need thereof. The method comprises administering to a subject in need thereof a therapeutically effective amount of a compound of the invention, or a pharmaceutically acceptable salt thereof, or a composition comprising a compound of the invention, or a pharmaceutically acceptable salt thereof.

Claim (Index 1):
A compound represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein: Q 1 , Q 2 , Q 3  and Q 4  are each independently selected from N and C(R 3 ), wherein no more than one of Q 1 , Q 2 , Q 3  and Q 4  is N;\n each R 3  is independently selected from hydrogen, amino, (C 1 -C 4 )alkylamino, (C 1 -C 4 )dialkylamino, halogen, C 1 -C 4  alkyl or C 1 -C 4  haloalkyl; \n R 1  is hydrogen or (C 1 -C 4 )alkyl; each of R 2a  and R 2b , if present, is independently hydrogen or (C 1 -C 4 )alkyl; m is 0, 1 or 2; and A is selected from: wherein:\n \u201c \u2020 \u201d represents the point of attachment of A to the remainder of the molecule; \n one \u201c \u201d represents a single bond and the other \u201c \u201d represents a double bond; \n X 1  is \u2014O\u2014, \u2014S\u2014 or \u2014N(R 10 )\u2014 and X 2  is \u2014C(R 11 )\u2014 or \u2014N\u2014; or X 1  is \u2014N\u2014 and X 2  is \u2014N(R 12 )\u2014, wherein:\n R 10  is hydrogen or (C 1 -C 4 )alkyl; \n R 11  is hydrogen, deuterium, (C 1 -C 4 )alkyl or halo; and \n R 12  is hydrogen or (C 1 -C 4 )alkyl; \n Y is \u2014O\u2014, \u2014S(O) 2 , \u2014NH\u2014 or \u2014N(C 1 -C 4 )alkyl-; each of R 20a  and R 20b  is independently hydrogen or (C 1 -C 4 )alkyl; Z 1  is \u2014O\u2014, \u2014S\u2014 or \u2014N(R 30 )\u2014; Z 2  and Z 3  are each independently \u2014C(R 31 )\u2014 or \u2014N\u2014, wherein:\n R 30  is hydrogen or (C 1 -C 4 )alkyl; and \n R 31  is hydrogen, (C 1 -C 4 )alkyl or halo; \n W 1  is \u2014O\u2014 or \u2014S\u2014; W 2  is \u2014C(O)\u2014 or \u2014C(H) 2 \u2014; and R 40  is hydrogen or (C 1 -C 4 )alkyl; each R 4  is independently carbocyclyl, heterocyclyl, halo, halo(C 1 -C 4 )alkyl, (C 1 -C 4 )alkyl, \u2014O\u2014(C 1 -C 4 )alkyl, \u2014O-halo(C 1 -C 4 )alkyl, cyano, sulfonate, or \u2014S(O) 0-2 (C 1 -C 4 )alkyl; R 5  is carbocyclyl or heterocyclyl; t is 1, 2 or 3; and p is 0, 1, 2 or 3, wherein each aryl, heteroaryl, carbocyclyl, heterocyclyl, alkyl or cycloalkyl is optionally and independently substituted.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 2.06061
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14902202', '15831111', '15023269', '14647662', '15482581']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7682141478480224
- 35 USC 102 Novelty (BERT): 0.533047443067957
- Combined Prediction Score: 0.7446974773700159
- Mean Citation Score: 299.7375600000001
- Max Citation Score: 343.36664
- Similarity Product: 226.9252807135869

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test