PATENT CLAIM ANALYSIS

Application Number: 16049240
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-12
Patent Classification: ["506", "009000"]

Abstract:
A system and method for isolating and analyzing single cells, comprising: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Claim (Index 1):
A method for analyzing a population of target cells from a biological sample, comprising:\n providing a substrate comprising a set of wells, wherein each well in the set of wells has a hexagonal open surface defined at the broad surface of a substrate, a base surface directly opposing the open surface, and a set of walls extending between the base surface and the open surface; distributing the biological sample containing the population of target cells across the hexagonal open surface of each well of the set of wells, capturing the population of target cells through the hexagonal open surface of each well into the set of wells in single-cell format, wherein exactly one of a single target cell settles into a single well of the set of wells in a direction perpendicular to the broad face of the substrate; flowing a reagent in a direction parallel to the broad surface of the substrate through a fluid reservoir laterally superior and directly fluidly connected to the set of wells; receiving the reagent through the hexagonal open surface of each well into the set of wells, without egressing the population of target cells from the set of wells; and analyzing the population of target cells in single-cell format.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 2.01852
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16049173', '15442222', '14289155', '15821329', '14863191']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.553212578447356
- 35 USC 102 Novelty (BERT): 0.5067465190544392
- Combined Prediction Score: 0.5485659725080644
- Mean Citation Score: 225.51608
- Max Citation Score: 281.47867
- Similarity Product: 236.6010751802004

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test