PATENT CLAIM ANALYSIS

Application Number: 15756407
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "019300"]

Abstract:
This disclosure provides compositions and methods for treating or preventing cardiac or vascular toxicity in a subject receiving a chemotherapeutic agent, where the cardiac or vascular toxicity is associated with administration of the chemotherapeutic agent. Also provided are compositions and methods for treating or preventing endothelial dysfunction and for modulating endothelial function and oxidative stress.

Claim (Index 20):
A method of treating a hyperproliferative disease in a subject, the method comprising administering to the subject a therapeutically effective amount of an isolated peptide into the subject, wherein said isolated peptide is less than 20 amino acids and comprises an amino acid sequence at least 80% homologous to the sequence as set forth by SEQ ID NO:6 (RRRGGX 1 ASRSLPLPKRPRR);\n wherein X 1  is a phosphomimetic residue selected from the group consisting of as aspartic acid and glutamic acid relative to the corresponding position in SEQ ID NO:1, the isolated peptide being capable of preventing TERT nuclear translocation, thereby treating the hyperproliferative disease.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 88.0
- Lexical Diversity: 1.56757
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12528465', '14243923', '15022280', '10148457', '12162135']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7305717957021973
- 35 USC 102 Novelty (BERT): 0.5152259614389068
- Combined Prediction Score: 0.7090372122758682
- Mean Citation Score: 278.669534
- Max Citation Score: 292.4309
- Similarity Product: 226.79182364106185

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test