PATENT CLAIM ANALYSIS

Application Number: 15769793
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["514", "323000"]

Abstract:
It is an object of the present invention to provide a novel therapeutic agent and method for treating amyotrophic diseases, and more specifically a therapeutic agent and method for treating neurogenic amyotrophic disorders such as amyotrophic lateral sclerosis (ALS) and myogenic amyotrophic disorders such as sarcopenia or disuse muscle atrophy. Provided is a therapeutic agent for amyotrophic diseases that comprises one or more compounds selected from the group consisting of compounds represented by the formula (I), the formula (II) and the formula (III), and pharmaceutically acceptable salts of the compounds when R 3  represents OH.

Claim (Index 1):
A method for treating an amyotrophic disease, comprising administering to a patient in need of a treatment of the amyotrophic disease, one or more compounds selected from the group consisting of compounds represented by the formula (I): wherein R 1  represents a benzoylmethyl group having a benzene ring unsubstituted or substituted with an alkyl group having 1 to 7 carbon atoms, an alkoxyl group having 1 to 7 carbon atoms, a fluorine atom and/or a chlorine atom; a linear or branched alkyl group having 4 to 6 carbon atoms unsubstituted or substituted with a fluorine atom; or a methylene or ethylene substituted with a phenyl group or a cyclopentyl group, wherein the phenyl group is optionally further substituted with one or more phenyl groups; R 2  is selected from the group consisting of hydrogen, an alkyl group having 1 to 4 carbon atoms, an alkoxyl group having 1 to 7 carbon atoms, a fluorine atom and a chlorine atom with which an indole is substituted at 4, 5, 6 and/or 7 positions/position; R 3  represents a group selected from any one of OH, OR 4 , NHR 4  and NR 4 R 5 ; and R 4  and R 5 , which are the same or different, each represent a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, the formula (II): wherein R 6  represents hydrogen or a methyl group; X represents an alkylene group having 4 to 6 carbon atoms or an ether group having 4 carbon atoms; R 3  represents a group selected from any one of OH, OR 4 , NHR 4  and NR 4 R 5 ; and R 4  and R 5 , which are the same or different, each represent a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and the formula (III): wherein A represents indole or naphthalene, provided that when A represents indole, indole is substituted with an acetate group and R 7 O at positions 3 and 5, respectively, and when A represents naphthalene, naphthalene is substituted with an acetate group and R 7 O at positions 1 and 7, respectively, wherein R 7  represents an alkyl group having 1 to 5 carbon atoms or a benzyl group, whose benzene ring is optionally substituted with one or more alkyl groups having 1 to 3 carbon atoms or one or more alkoxy groups having 1 to 3 carbon atoms; R 3  represents a group selected from any one of OH, OR 4 , NHR 4  and NR 4 R 5 ; and R 4  and R 5 , which are the same or different, each represent a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and pharmaceutically acceptable salts of the compounds when R 3  represents OH.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 95.0
- Lexical Diversity: 1.74194
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14646640', '16017520', '15873571', '15429738', '15318735']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.756371668208213
- 35 USC 102 Novelty (BERT): 0.517361578215302
- Combined Prediction Score: 0.7324706592089218
- Mean Citation Score: 249.208048
- Max Citation Score: 301.81195
- Similarity Product: 204.26690721997025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test