PATENT CLAIM ANALYSIS

Application Number: 15781925
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "253010"]

Abstract:
A problem of the present invention is to provide a new compound which has NK 1  receptor antagonist activity, and thus is useful for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting. A compound represented by the formula (I): wherein W represents a fluorine atom and the like, ring A represents a cycloalkyl and the like, X 1  represents CH or N, R represents methyl and the like, Y represents 0 to 2, U 1 , U 2  and U 3  each independently represents a single bond and the like, or a pharmaceutically acceptable salt thereof. The compounds of the present invention or pharmaceutically acceptable salts thereof have an excellent NK 1  receptor antagonist activity, and thus are also useful as an agent for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting.

Claim (Index 1):
A compound represented by the formula (I): wherein W is a hydrogen atom or a fluorine atom; Ring A is a group selected from the group consisting of the following (a) to (d): wherein bond with * is a bonding site to the U 2 ; k represents an integer number 1 to 5; r is 1 or 2; m and n are independently 1, 2 or 3; X 1  is CH or N; R is a methyl, hydroxy or a halogen atom; Y is 0, 1 or 2; when Y is 2, two R are optionally different from each other; U 1 , U 2  and U 3  are each independently a single bond, carbonyl or a methylene which may have any group selected from substituent group \u03b1; when ring A is a group represented by the above (a), either one of U 1  or U 2  is carbonyl; substituent group \u03b1 is a group consisting of a halogen atom, hydroxy, a C 1-6  alkyl and a C 1-6  alkoxy; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 2.0
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15630238', '15308996', '15034808', '13119743', '13234514']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7963676581308774
- 35 USC 102 Novelty (BERT): 0.5468331944269071
- Combined Prediction Score: 0.7714142117604803
- Mean Citation Score: 329.736904
- Max Citation Score: 388.08267
- Similarity Product: 341.13526431648546

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test