PATENT CLAIM ANALYSIS

Application Number: 15878282
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["435", "091200"]

Abstract:
Techniques, systems, and devices are disclosed for non-thermal cycling of polymerase chain reaction (PCR). In one aspect, a method for cycling PCR includes receiving an electrolytic fluid including ions, primers, polymerase enzymes, nucleotides, and a double-stranded nucleic acid in a fluid chamber having a first electrode and a second electrode, applying an electric field across the first and the second electrodes to generate a first pH level of the electrolytic fluid to denature the double-stranded nucleic acid to at least partial single strands, and applying a second electric field across the first and second electrodes to produce a second pH level of the electrolytic fluid, in which the second pH level enables binding of a polymerase enzyme and a primer with a corresponding segment of the single strands.

Claim (Index 2):
The device as in  claim 1 , further comprising a third electrode pair located in the channel in contact with the electrolytic surface and spaced apart from the first and the second electrode pairs along the channel,\n wherein the circuit is electrically coupled to the third electrode pair to apply a third electric field across the third pair to generate a third pH level of the electrolytic fluid, wherein the third pH level enables the synthesis of new complementary nucleic acid strands from the nucleotides using the at least partial single strands.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 2.1194
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15224873', '13830397', '15018111', '11128301', '12321825']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5154661685242298
- 35 USC 102 Novelty (BERT): 0.5380766190213002
- Combined Prediction Score: 0.5177272135739368
- Mean Citation Score: 238.380048
- Max Citation Score: 369.18042
- Similarity Product: 256.330656014843

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test