PATENT CLAIM ANALYSIS

Application Number: 15764264
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["546", "209000"]

Abstract:
Problem to be Solved There is a need for a new antibiotic having a novel mechanism of action which exhibit strong antibacterial activity not only against sensitive bacteria but also against resistant bacteria thereof, and at the same time possesses excellent solubility an a safety profile amenable to human use. Solution to the Problem As a result of intensive research, the present inventors have found that a compound represented by general formula (I), a stereoisomer, or a pharmaceutically acceptable salt thereof inhibits DNA gyrase GyrB subunit and/or topoisomerase IV ParE subunit possesses excellent solubility and a safety profile for use in humans for the treatment of bacterial infectious diseases.

Claim (Index 7):
The compound according to  claim 4 , wherein 4-chloro-N-[(3S,4R)-1-{5-[(2S)-1,2-dihydroxypropan-2-yl]-1,3,4-thiadiazol-2-yl}-3-methoxypiperidin-4-yl]-5-ethyl-1H-imidazole-2-carboxamide is crystalline solid, designated as Form B, characterized by powder x-ray diffraction (XRD) spectrum (CuK, \u03bb=1.54 \u212b), wherein Form B has characteristic peaks 2\u03b8 (d) at 13.13 (6.73), 14.27 (6.20), and 19.10 (4.64).

Metadata:
- Claim Count in Document: 36.0
- Percentile: 90.0
- Lexical Diversity: 1.39286
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15547776', '15262112', '12187115', '11884923', '15314562']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8194013318445075
- 35 USC 102 Novelty (BERT): 0.5127551852430229
- Combined Prediction Score: 0.7887367171843591
- Mean Citation Score: 296.5449680000001
- Max Citation Score: 311.3937
- Similarity Product: 236.90001309839488

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test