PATENT CLAIM ANALYSIS

Application Number: 15944336
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["549", "265000"]

Abstract:
Provided is a compound that comprises the structure: where SIG is a signaling molecule and R 3  is a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presence of the enzyme. Additionally, a method is provided for determining whether a sample has an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine. Also provided is a method of determining whether a molecule inhibits an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine.

Claim (Index 6):
The method of  claim 1 , wherein the compound is a substrate for a peptidase after the enzyme cleaves the myristoyl moiety from the compound but not if the the myristoyl moiety is not removed from the compound;\n wherein the determining step further comprises\n (i) adding the peptidase to the mixture under conditions and for a time sufficient for the peptidase to cleave the resulting molecule between the nitrogen bound to SIG and the carbonyl carbon bound to said nitrogen, such that SIG generates an increased signal relative to the signal generated with the compound; and \n (ii) determining whether SIG generates an increased signal relative to the signal generated with the compound, \n wherein an increased signal indicates the removal of the myristoyl moiety from the compound.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 2.80435
- Patent Class: 549.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15464966', '12930693', '13808706', '13698561', '13516190']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7370971617751783
- 35 USC 102 Novelty (BERT): 0.7291139780421303
- Combined Prediction Score: 0.7362988434018736
- Mean Citation Score: 499.612722
- Max Citation Score: 793.6410000000003
- Similarity Product: 777.327883084059

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test