PATENT CLAIM ANALYSIS

Application Number: 15746838
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "365000"]

Abstract:
The present invention includes novel aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.

Claim (Index 24):
A method of preventing or treating cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a composition comprising at least one compound of formula (I): including enantiomers, diastereomers, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof; wherein in formula (I):\n X is selected from the group consisting of \n n is 1, 2, 3 or 4; R 1a  and R 1b  are at each occurrence independently selected from the group consisting of hydrogen, C 1-4  linear alkyl, and C 3-6  branched alkyl, or R 1a  and R 1b  are taken together with the atoms to which they are bound to form a three to six membered carbocyclic ring, or two R 1a  units on adjacent carbon atoms are taken together with the atoms to which they are bound to form a three to six membered carbocyclic ring; R 2a , R 2b , and R 2c  are each independently selected from the group consisting of hydrogen, halogen, hydroxyl, C 1-6  linear alkyl, C 3-6  branched alkyl, C 3-6  cycloalkyl, C 1-6  haloalkyl, C 1-6  linear alkoxy, C 3-6  branched alkoxy, C 1-6  haloalkoxy, thiol, C 1-6  linear thioalkyl, C 3-6  branched thioalkyl, cyano, nitro, and NH 2 : R 3a  and R 3b  are each independently selected from the group consisting of hydrogen, C 1-4  linear alkyl, and C 3-6  branched alkyl; R 4  is selected from the group consisting of C 1-6  optionally substituted linear alkyl, C 3-7  optionally substituted branched alkyl, C 3-10  optionally substituted cycloalkyl, C 4-9  optionally substituted heteroaryl, C 4-9  optionally substituted heteroarylalkyl, X 1  is selected from the group consisting of O, NR 11 , S, SO, and SO 2 ; R 5  is selected from the group consisting of hydrogen, C 1-6  linear alkyl, C 3-7  branched alkyl, C 3-7  cycloalkyl, and COR 8 ; R 6a  and R 6b  are at each occurrence independently selected from the group consisting of hydrogen, C 1-6  linear alkyl, and C 3-6  branched alkyl; q is 1 or 2; R 7  is selected from the group consisting of C 1-6  linear alkyl, C 3-6  branched alkyl, CF 3 , and C 1-3  haloalkyl; R 8  is selected from the group consisting of hydrogen, C 1-6  linear alkyl, C 3-7  branched alkyl, C 1-6  linear alkoxy, C 3-7  branched alkoxy, and C 3-7  cycloalkyl; R 9  at each occurrence is independently selected from the group consisting of hydrogen, methyl, ethyl, and n-propyl; R 10a , R 10b , R 10c , R 10d , and R 10e  are each independently selected from the group consisting of hydrogen, halogen, hydroxyl, C 1-6  linear alkyl, C 3-6  branched alkyl, C 3-6  cycloalkyl, C 1-6  haloalkyl, C 1-6  linear alkoxy, C 3-6  branched alkoxyl, C 1-6  haloalkoxy, thiol, C 1-6  linear thioalkyl, C 3-6  branched thioalkyl, cyano, nitro, NH 2 , and NR 11a R 11b ; R 11  is selected from the group consisting of hydrogen and C 1-6  linear alkyl; R 11a  and R 11b  are each independently selected from the group consisting of C 1-6  linear alkyl and C 3-6  branched alkyl; R 11  is selected from the group consisting of hydrogen and C 1-6  linear alkyl; y is 1, 2, or 3; and z is 1, 2, or 3.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.82759
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15873293', '13863089', '15036743', '15130893', '15549152']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7908002364405402
- 35 USC 102 Novelty (BERT): 0.5232266191812927
- Combined Prediction Score: 0.7640428747146155
- Mean Citation Score: 294.155088
- Max Citation Score: 331.12177
- Similarity Product: 234.21877208798

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test