PATENT CLAIM ANALYSIS

Application Number: 15881806
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["210", "739000"]

Abstract:
A system for collecting MNCs to be treated with irradiation comprises a fluid circuit comprising a product container for receiving a MNC product. The system comprises a separator to work in association with the fluid circuit, the separator comprising a chamber for separation into RBCs, plasma, and an interface carrying MNCs between the RBCs and the plasma. A microprocessor-based controller is in communication with the separator, wherein the controller receives input of a target hematocrit for the MNC product. The controller also receives input for a total volume of whole blood and a number of cycles, and directs the interface and a portion of the RBCs into the product container for a resulting product volume comprising a volume of MNCs and a volume of RBCs. The controller automatically adjusts a RBC volume so that a ratio of RBCs within the MNC product to MNC product equals the target hematocrit.

Claim (Index 7):
A method for collecting diluted mononuclear cells to be treated with UV irradiation, driven and adjusted by a microprocessor-based controller, comprising the steps of:\n receiving input of a target hematocrit for a mononuclear cell product to be collected in a first container comprising mononuclear cells, red blood cells, and plasma, wherein hematocrit is determined by a ratio of the red blood cells per volume within the mononuclear cell product; receiving input for a total volume of whole blood to be processed and a number of cycles to be performed; rotating a chamber about a rotational axis and conveying whole blood into an inlet region of the chamber for separation into a red blood cell constituent, a plasma constituent, and an interface carrying mononuclear cells between the red blood cell constituent and the plasma constituent, wherein separation is performed across a plurality of cycles; in a first cycle, directing the interface and a portion of the red blood cell constituent into the first container by opening a valve disposed between the chamber and the first container for a first product volume comprising a first volume of mononuclear cells and a first volume of red blood cells; in a second cycle, directing the interface and red blood cell constituent into the first container by opening the valve for a second product volume comprising a second volume of mononuclear cells and a second volume of red blood cells; wherein the microprocessor-based controller is configured to automatically adjust the first and/or second product volumes so that a volume ratio of a total volume of red blood cells within the mononuclear cell product to a total volume of mononuclear cell product equals the target hematocrit.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 86.0
- Lexical Diversity: 2.44615
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14758328', '15189752', '13733607', '14976950', '14828226']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8099415115720738
- 35 USC 102 Novelty (BERT): 0.5169000903059421
- Combined Prediction Score: 0.7806373694454607
- Mean Citation Score: 294.351388
- Max Citation Score: 331.71875
- Similarity Product: 245.5314709059894

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test