PATENT CLAIM ANALYSIS

Application Number: 15781121
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "224200"]

Abstract:
Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed. (I)

Claim (Index 2):
The compound according to  claim 1 , selected from:\n (2S,5R)\u2014N-{[(2S,4S)-4-(2H-tetrazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-tetrazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(2H-1,2,3-triazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-1,2-pyrazol-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-1,2,4-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(2H-tetrazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-tetrazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(2H-1,2,3-triazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-1,2,4-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-1,2-pyrazol-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-pyrrol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-pyrrol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(4-amino-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(2-methyl-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1H-benzimidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-benzimidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(2H-tetrazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-tetrazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(2H-1,2,3-triazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-1,2,4-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-1,2-pyrazol-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-pyrrole-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-pyrrole-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(4-amino-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(2-methyl-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1H-benzimidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-pyrrole-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(2H-tetrazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-tetrazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(2H-1,2,3-triazol-2-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-1,2,4-triazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-1,2-pyrazol-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(4-amino-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(2-methyl-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(4-amino-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(2-methyl-1H-1,3-imidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-benzimidazol-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(piperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(piperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(piperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(piperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(4-hydroxypiperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(4-hydroxypiperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(4-hydroxypiperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(4-hydroxypiperidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(piperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(piperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(piperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(piperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(4-methylpiperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(4-methylpiperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(4-methylpiperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(4-methylpiperizin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(morpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(morpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(morpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(morpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(thiomorpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(thiomorpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(thiomorpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(thiomorpholin-4-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(azeditin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(azeditin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(azeditin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(azeditin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1,3-Oxazeditin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1,3-Oxazeditin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1,3-Oxazeditin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1,3-Oxazeditin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(pyrrolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(pyrrolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(pyrrolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(pyrrolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(pyrazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(pyrazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(pyrazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(pyrazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(imidazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(imidazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(imidazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(imidazolidin-1-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1,3-oxazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1,3-oxazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1,3-oxazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1,3-oxazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4R)-4-(1,3-thiazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2S,4S)-4-(1,3-thiazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4R)-4-(1,3-thiazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-(1,3-thiazolidin-3-yl)pyrrolidin-2-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N-{[(2R,4S)-4-[4-({[(2S)-1-hydroxypropan-2-yl]amino}methyl)piperidin-1-yl]pyrrolidin-2-yl]methoxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (2S,5R)\u2014N\u2032-{[(2S,4S)-4-(1H-tetrazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2S,4S)-4-(2H-tetrazol-2-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2S,4S)-4-(5-methyl-2H-tetrazol-2-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2R,5R)\u2014N\u2032-{[(2S,4S)-4-(2H-1,2,3-triazol-2-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2R,5R)\u2014N\u2032-{[(2S,4S)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2R,5R)-7-oxo-6-(sulfooxy)-N\u2032-{[(2S,4S)-4-(1H-1,2,4-triazol-1-yl)pyrrolidin-2-yl]carbonyl}-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2S,4S)-4-(1H-imidazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2RS, 4S)-4-(1H-imidazol-1-yl) pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N-{[(2S,4R)-4-(1H-pyrazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2SR, 4S)-4-(1H-pyrazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N\u2032-{[(2S,4R)-4-(1H-imidazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; (2S,5R)\u2014N-{[(2R,4S)-4-(1H-imidazol-1-yl)pyrrolidin-2-yl]carbonyl}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxyhydrazide; or a stereoisomer or a pharmaceutically acceptable derivative thereof.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 94.0
- Lexical Diversity: 1.19048
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15547487', '12812763', '15171237', '14452652', '14609704']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8258932855818354
- 35 USC 102 Novelty (BERT): 0.607978086225517
- Combined Prediction Score: 0.8041017656462035
- Mean Citation Score: 441.61196600000005
- Max Citation Score: 546.4837
- Similarity Product: 494.0175754554869

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test