PATENT CLAIM ANALYSIS

Application Number: 15906745
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "210180"]

Abstract:
Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.

Claim (Index 1):
A compound of formula (I):\n A-B\u2014C\u2003\u2003(I) wherein: A is B is alkylene, -alkylene-(O); -alkylene-N(R)C(O)\u2014, -alkylene-(heterocyclyl)-C(O)\u2014, -alkylene-C(O)N(R)\u2014, -alkylene-C(O)\u2014, -alkylene-N(R)\u2014, -alkylene-N (R)C(O)N(R)\u2014, -alkylene-N(R)SO 2 \u2014, -alkylene-(aryl)-, -alkylene-(heterocyclyl)-, -alkylene-(heterocyclyl)-alkylene-, -aryl-alkylene-N(R)C(O)\u2014; -aryl-C(O)N(R)\u2014, -aryl-N(R)C(O)\u2014, -(heterocyclyl)-alkylene-, -heterocyclyl-alkylene-N(R)C(O)\u2014; -heterocyclyl-C(O)N(R)\u2014, \u2014O-heterocyclyl-; -alkylene-O\u2014; -heterocyclyl-C(O)\u2014; cycloalkylene; or clycloalkylene-O\u2014; C is R is H, alkyl, or aryl; R 1  is independently H, alkyl, halide, alkoxy, CF 3 , OH, alkylene-OH, NO 2 , \u2014N(H)R, or NH 2 ; R 2  is H, alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, cycloalkyl, -alkylene-alkoxy, alkylene-aryl, or heterocycloalkyl; are a 3-12 membered heterocycloalkylene unsubstituted or substituted by one or more instance of R 1 ;\n X is C(R c ) or N; \n both instances of R a  are H, or taken together form a bond, or a (C 1 -C 4 )alkylene bridge; \n R b  is H, or (C 1 -C 6 )alkyl; and \n R c  is H, alkyl, aryl, OH, or halide; \n or a pharmaceutically acceptable salt thereof; \n provided that the compound of formula (I) is not

Metadata:
- Claim Count in Document: 38.0
- Percentile: 88.0
- Lexical Diversity: 1.15
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14448941', '12728153', '15612030', '12975900', '13646143']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7717558572039075
- 35 USC 102 Novelty (BERT): 0.5272179499318589
- Combined Prediction Score: 0.7473020664767026
- Mean Citation Score: 308.308034
- Max Citation Score: 312.28763
- Similarity Product: 216.5071552396249

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test