PATENT CLAIM ANALYSIS

Application Number: 16011870
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["546", "153000"]

Abstract:
A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.

Claim (Index 22):
A method of storing a pitavastatin calcium salt, comprising:\n maintaining a water content of the pitavastatin calcium salt at greater than 4% (w/w) and at most 15% (w/w); wherein: the pitavastatin calcium salt is a compound according to formula (1): an X-ray powder diffraction pattern of the pitavastatin calcium salt, as measured using CuK\u03b1 radiation, exhibits peaks at diffraction angles (2\u03b8) of 4.96\u00b0, 6.72\u00b0, 9.08\u00b0, 10.40\u00b0, 10.88\u00b0, 13.20\u00b0, 13.60\u00b0, 13.96\u00b0, 18.32\u00b0, 20.68\u00b0, 21.52\u00b0, 23.64\u00b0, 24.12\u00b0, 27.00\u00b0, and 30.16\u00b0; and a water content of the pitavastatin calcium salt at an initial stage is from 7% (w/w) to 13% (w/w).

Metadata:
- Claim Count in Document: 68.0
- Percentile: 94.0
- Lexical Diversity: 1.58696
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13818681', '13665932', '15749377', '13884734', '15532281']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.731009558802271
- 35 USC 102 Novelty (BERT): 0.5000090590357439
- Combined Prediction Score: 0.7079095088256183
- Mean Citation Score: 192.428704
- Max Citation Score: 237.1111
- Similarity Product: 158.1525656313598

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test