PATENT CLAIM ANALYSIS

Application Number: 16243091
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2020-02
Patent Classification: ["null", "null"]

Abstract:
A method for preparing 5-(4-bromophenyl)-4,6-dichloropyrimidine is provided. The method comprises the steps of: preparing methyl p-bromophenylacetate (Intermediate I) by catalytic esterification of p-bromophenylacetic acid, and then reacting with dimethyl carbonate to synthesize 2-(4-bromophenyl)-malonic acid-1,3-dimethyl ester (Intermediate 2), cyclizing with formamidine hydrochloride to obtain 5-(4-bromophenyl)-4,6-dihydroxypyrimidine (Intermediate 3), and then chlorinating to give the product 5-(4-bromophenyl)-4,6-dichloropyrimidine. In the process of preparing Intermediate 1 in the present invention, a solid acid is used as a catalyst. Moreover, in the process of preparing Intermediate 2, sodium methoxide is used as a base in place of sodium hydride or sodium amide used in the prior art. Furthermore, Intermediate 3 is prepared by a one-pot process.

Claim (Index 4):
The method for preparing 5-(4-bromophenyl)-4,6-dichloropyrimidine according to  claim 1 , wherein the weight ratio of p-bromophenylacetic acid to the solid acid catalyst is 1:0.4-0.6; Intermediate 1 is methyl p-bromophenylacetate; and the weight ratio of methyl p-bromophenylacetate, dimethyl carbonate, sodium methoxide, and formamidine hydrochloride is 1:1.0-1.5:0.6-1.0:0.35-0.55.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 99.0
- Lexical Diversity: 1.95946
- Patent Class: nan
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13521780', '15535413', '15521021', '14399929', '14673427']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5576823640427693
- 35 USC 102 Novelty (BERT): 0.4950818110740687
- Combined Prediction Score: 0.5514223087458993
- Mean Citation Score: 222.156194
- Max Citation Score: 235.4971
- Similarity Product: 169.64392172713875

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test