PATENT CLAIM ANALYSIS

Application Number: 15940432
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences. Also provided are vaccine formulations comprising mammalian or avian MPV, including recombinant and chimeric forms thereof. The vaccine preparations encompass multivalent vaccines, including bivalent and trivalent vaccine preparations.

Claim (Index 85):
A kit for determining the presence of metapneumovirus (MPV) in a mammalian subject, the kit comprising:\n a DNA probe of at least 10 nucleotides that specifically hybridizes to a target polynucleotide, wherein the DNA probe does not specifically hybridize to a polynucleotide from avian pneumovirus (APV); wherein the probe does not hybridize under stringent conditions to a sequence encoding a polypeptide of SEQ ID NOs:314 and 316 or the complement of the sequence; wherein the stringent conditions include a hybridization buffer comprising 6\u00d7SSC and 1 mM EDTA; and wherein the target polynucleotide comprises a first nucleic acid encoding a polypeptide that is at least 90% identical to SEQ ID NO:315 or the complement of the first nucleic acid; or wherein the target polynucleotide comprises a second nucleic acid encoding a polypeptide that is at least 90% identical to SEQ ID NO:317 or the complement of the second nucleic acid.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 2.10345
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15804585', '15404854', '14270237', '14460285', '12284347']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8307444314311907
- 35 USC 102 Novelty (BERT): 0.690493045829345
- Combined Prediction Score: 0.8167192928710061
- Mean Citation Score: 728.6900760000003
- Max Citation Score: 749.48175
- Similarity Product: 705.6704441277982

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test