PATENT CLAIM ANALYSIS

Application Number: 16069546
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["424", "001890"]

Abstract:
Radiolabeled compounds which are erlotinib analogs that feature a radioactive halogen and processes of preparing same are disclosed. Uses of these radiolabeled compounds in radioimaging, for identifying and monitoring a level, distribution and/or mutational status of deregulated EGFR, and/or in radiotherapy, are also disclosed.

Claim (Index 48):
A radiolabeled compound represented by general Formula Ia or Ib: wherein:\n the dashed line in Formula Ia represents an optional unsaturated bond; \n R 1 -R 21 , Ra and Rb are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroalicyclic, heteroaryl, alkoxy, aryloxy, thioalkoxy, thioaryloxy, hydroxyl, halogen, trihaloalkyl, trihaloalkoxy, amine, cyano, nitro, carbonyl, thiocarbonyl, carboxylate, thioacarboxylate, amide, thioamide, carbamate, thiocarbamate, alkaryl, aralkyl, sulfinyl, sylfonyl, sulfonate, and sulfonamide; \n Rc and Rd are each absent, in case the dashed line represents an unsaturated bond, or are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, heteroalicyclic, heteroaryl, alkoxy, aryloxy, thioalkoxy, thioaryloxy, hydroxyl, halogen, trihaloalkyl, trihaloalkoxy, amine, cyano, nitro, carbonyl, thiocarbonyl, carboxylate, thioacarboxylate, amide, thioamide, carbamate, thiocarbamate, alkaryl, aralkyl, sulfinyl, sylfonyl, sulfonate, and sulfonamide; and \n Y 1  and Y 2  are each independently selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroalicyclic, heteroaryl, alkoxy, aryloxy, thioalkoxy, thioaryloxy, hydroxyl, halogen, trihaloalkyl, trihaloalkoxy, amine, cyano, nitro, carbonyl, thiocarbonyl, carboxylate, thioacarboxylate, amide, thioamide, carbamate, thiocarbamate, acrylate, methacrylate, acrylamide, alkaryl, aralkyl, sulfinyl, sylfonyl, sulfonate, sulfonamide, a substituted or unsubstituted, saturated or unsaturated hydrocarbon chain of 1 to 20 carbon atoms, optionally interrupted by one or more heteroatoms, a radioactive halogen, and Q, \n wherein Q is a chemical moiety comprising a radioactive halogen, \n provided that at least one of Y 1  and Y 2  is or comprises a radioactive halogen.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 95.0
- Lexical Diversity: 1.38889
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11714760', '10659747', '12449129', '14023681', '12631116']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4496353699862924
- 35 USC 102 Novelty (BERT): 0.5116335747322711
- Combined Prediction Score: 0.4558351904608902
- Mean Citation Score: 235.110082
- Max Citation Score: 283.49173
- Similarity Product: 211.03414019266543

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test