PATENT CLAIM ANALYSIS

Application Number: 15765387
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "339000"]

Abstract:
The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.

Claim (Index 11):
The compound or the pharmaceutically acceptable salt thereof according to  claim 1 , wherein X represents NH, Y represents hydroxy, R 2 , R 3  and R 4  represent hydrogen, R 5  represents hydroxy or C 1 -C 4  alkoxy, L represents \u2014CH 2 \u2014 or \u2014CH 2 O\u2014, n represents 0 or 1, and R 1  represents substituted phenyl, wherein the substituent is C 1 -C 4  alkyl, C 1 -C 4  alkoxy or halogen.

Metadata:
- Claim Count in Document: 31.0
- Percentile: 91.0
- Lexical Diversity: 1.68571
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15561471', '15561464', '15561435', '15436596', '14652024']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7860285186575646
- 35 USC 102 Novelty (BERT): 0.5139182168805408
- Combined Prediction Score: 0.7588174884798623
- Mean Citation Score: 304.16361
- Max Citation Score: 316.42633
- Similarity Product: 278.827474746567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test