PATENT CLAIM ANALYSIS

Application Number: 15775368
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2018-11
Patent Classification: ["366", "198000"]

Abstract:
The present invention is based in part on the discovery of significant improvements to cell culture systems and methods of generating organoids. The system of the invention provides a novel spinning bioreactor platform for higher-throughput 3D culturing of stem cells (e.g. human induced pluripotent stem cells (iPSCs) or embryonic stem cells (ESCs)). The system can be widely used as a standard platform to generate stem cell-derived human organoids for any tissue and for high-throughput drug screenings, toxicity testing, and modeling normal human organ development and diseases.

Claim (Index 7):
The cell culture system of  claim 1 , further comprises a second multiwell culture plate, the second multiwell culture plate comprising:\n a) a base substrate having a plurality of culture wells; and b) a shaft associated with each culture well, each shaft being configured to mix media present in each culture well and having a gear adapted to operably associate with a gear on a shaft associated with an adjacent culture well, wherein the motor is in operable communication with the shaft gears of the second multiwell culture plate via a second intermediate gear operably associated with the drive shaft, and wherein rotation of the drive shaft causes rotation of each shaft and mixing of the media in each culture well of the second multiwell plate.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 97.0
- Lexical Diversity: 1.48485
- Patent Class: 366.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14651346', '15136250', '14722065', '13147163', '15865574']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7873193372119146
- 35 USC 102 Novelty (BERT): 0.5053965204947082
- Combined Prediction Score: 0.759127055540194
- Mean Citation Score: 230.397314
- Max Citation Score: 251.59143
- Similarity Product: 116.63991131987392

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test