PATENT CLAIM ANALYSIS

Application Number: 16018247
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "072000"]

Abstract:
The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.

Claim (Index 4):
The engineered transaminase polypeptide of  claim 3 , wherein the transaminase polypeptide sequence comprises the substitution X417C and at least one further substitution selected from: X4 is R, Q, or L; X12 is K; X21 is N; X45 is H; X86 is Y; X157 is T; X177 is L; X208 is I; X211 is K; X253 is M; X272 is A; X294 is V; X302 is K; X316 is K; X324 is G; X391 is A; X398 is R; X418 is V; X420 is N; X431 is D; X444 is V; and X446 is V.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.47368
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14684916', '15912892', '15341631', '13920902', '13381155']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7818468843256773
- 35 USC 102 Novelty (BERT): 0.7571398936978556
- Combined Prediction Score: 0.7793761852628951
- Mean Citation Score: 789.1678159999999
- Max Citation Score: 898.8333
- Similarity Product: 866.0636216689111

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test