PATENT CLAIM ANALYSIS

Application Number: 16003990
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["546", "081000"]

Abstract:
The present invention relates to compounds of formulas III and V that are useful as pharmaceutical agents, particularly as autophagy inhibitors.

Claim (Index 1):
A compound of formula III or a pharmaceutically acceptable salt thereof, wherein:\n Q is CH or N; \n R N  is \u2014H; \n R 1  is \u2014H, \u2014F, \u2014Cl, \u2014Br, or \u2014CF 3 ; \n R 2  is \u2014CH(R 2-1 )\u2014(CH 2 ) n2 \u2014X\u2014;\n R 2-1  is \u2014H, C 1 -C 3  alkyl, or C 3  cycloalkyl; \n n 2  is 3; \n X is \u2014NX 1-2 X 1-3 , where X 1-2  is H, linear or branched C 1 -C 4  alkyl, cyclopropyl, cyclobutyl, \u2014SO 2 \u2014X 1-4  where X 1-4  is selected from H and C 1 -C 3  alkyl, and \u2014CO\u2014X 1-4  where X 1-4  is as defined above; where X 1-3  is linear or branched C 1 -C 4  alkyl optionally substituted with one cyclopropyl; and where X 1-2  and X 1-3  may be taken together with the attached nitrogen atom to form a monocyclic structure; \n \n R 3  is \u2014H, \u2014F, \u2014Cl, \u2014Br, \u2014CF 3 , \u2014OR 3-1  where R 3-1  is \u2014H, C 1 -C 6  alkyl or \u2014CO\u2014R 3-2  where R 3-2  is C 1 -C 3  alkyl or phenyl, \u2014N(R 3-1 ) 2  where the R 3-1  are the same or different and are as defined above, \u2014SR 3-1  where R 3-1  is as defined above, \u2014S(O)\u2014R 3-1  where R 3-1  is as defined above, or \u2014SO 2 \u2014R 3-1  where R 3-1  is as defined above; \n R 4  is \u2014H , \u2014F, \u2014Cl, \u2014Br, \u2014CF 3 , \u2014OR 4-1  where R 4-1  is \u2014H, C 1 -C 6  alkyl or \u2014CO\u2014R 4-2  where R 4-2  is C 1 -C 3  alkyl or phenyl, \u2014N(R 4-1 ) 2  where the R 4-1  are the same or different and are as defined above, \u2014SR 4-1  where R 4-1  is as defined above, \u2014S(O)\u2014R 4-1  where R 4-1  is as defined above, or \u2014SO 2 \u2014R 4-1  where R 4-1  is as defined above; and \n R 5  is \u2014H, \u2014F, \u2014Cl, \u2014Br, \u2014CF 3 , \u2014OR 5-1  where R 5-1  is H, C 1 -C 6  alkyl or \u2014CO\u2014R 5-2  where R 5-2  is C 1 -C 3  alkyl or phenyl, \u2014N(R 5-1 ) 2  where the R 5-1  are the same or different and are as defined above, \u2014SR 5-1  where R 5-1  is as defined above, \u2014S(O)\u2014R 5-1  where R 5-1  is as defined above, or \u2014SO 2 \u2014R 5-1  where R 5-1  is as defined above;\n with the proviso that one of R 1 , R 3 , R 4  and R 5  must be other than \u2014H.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.04545
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14116650', '15384823', '13995889', '14173072', '12316848']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7397824138546152
- 35 USC 102 Novelty (BERT): 0.5341749230855853
- Combined Prediction Score: 0.7192216647777122
- Mean Citation Score: 256.67405799999995
- Max Citation Score: 352.04474
- Similarity Product: 274.8200610843694

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test