PATENT CLAIM ANALYSIS

Application Number: 16048104
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-12
Patent Classification: ["422", "503000"]

Abstract:
A cell capture system including an array, an inlet manifold, and an outlet manifold. The array includes a plurality of parallel pores, each pore including a chamber and a pore channel, an inlet channel fluidly connected to the chambers of the pores; an outlet channel fluidly connected to the pore channels of the pores. The inlet manifold is fluidly connected to the inlet channel, and the outlet channel is fluidly connected to the outlet channel. A cell removal tool is also disclosed, wherein the cell removal tool is configured to remove a captured cell from a pore chamber.

Claim (Index 1):
A system for isolating and analyzing a set of particles from a biological sample, comprising:\n a substrate defining a set of chambers at a broad surface, wherein each chamber in the set of chambers is configured to retain a single particle of the set of particles and comprises:\n a set of walls defining a chamber volume, a chamber length, and a chamber cross-section; and \n an open surface permitting access of the single particle to the chamber volume from a direction perpendicular to the broad surface of the substrate; \n an inlet channel positioned superior the set of chambers and directly fluidly coupled to the set of chambers, whereby fluid received at the inlet channel can concurrently access each of the chambers in the set of chambers at the open surface of each chamber; a fluid delivery module fluidly coupled to the inlet channel, wherein the fluid delivery module comprises a reagent delivery mode operable to distribute a reagent fluid in a direction substantially parallel to the broad surface through the inlet channel, permitting access of the reagent fluid to the set of chambers; and an imaging subsystem comprising:\n an optical assembly positioned at a first side of the substrate and oriented in a direction perpendicular to the broad surface of the substrate; and \n an automated stage configured to align a selected chamber of the of the set of chambers with an objective of the optical assembly.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 95.0
- Lexical Diversity: 2.65854
- Patent Class: 422.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16048073', '15657553', '15333420', '14607918', '13557510']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8542261900443308
- 35 USC 102 Novelty (BERT): 0.4987555747218467
- Combined Prediction Score: 0.8186791285120824
- Mean Citation Score: 288.87793
- Max Citation Score: 317.3193
- Similarity Product: 294.2312089397728

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test