PATENT CLAIM ANALYSIS

Application Number: 15916596
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-09
Patent Classification: ["514", "308000"]

Abstract:
Bis-benzyl-tetrahydroisoquinoline analogs that are derivatives of the cyclic products tetrandrine (TETN) and cepharanthine (CEPH). The analogs indicate activity against filovirus infections, including the type species Marburg virus (MARV) and Ebola virus (EBOV).

Claim (Index 10):
A method for treating an individual infected with or exposed to a filovirus comprising administering to said individual as an active ingredient a compound of Formula 4: wherein R 1 , R 2 =Me; R 1  and V can combine to form a dioxolane ring; R 2  and W can combine to form a dioxolane ring; V, W\u2550H, OMe; R 3 , R 4 \u2550H, Me, isopropyl, benzyl and C(O)\u2014(CH 2 )n-NMe 2 , n=1-3; X\u2550H, OMe; Z\u2014Y\u2550C\u2014H, C\u2014OMe, N; or a pharmaceutical salt thereof.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 90.0
- Lexical Diversity: 1.34375
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15540972', '16081696', '10524281', '15540239', '15577771']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7652345356498668
- 35 USC 102 Novelty (BERT): 0.5171383962166102
- Combined Prediction Score: 0.7404249217065411
- Mean Citation Score: 276.436862
- Max Citation Score: 283.72647
- Similarity Product: 183.3267110649133

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test