PATENT CLAIM ANALYSIS

Application Number: 15987793
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["435", "006120"]

Abstract:
A method of sample analysis is provided. In certain embodiments, the method involves: a) amplifying a product from a sample that comprises both wild type copies of a genomic locus and mutant copies of the genomic locus that have a point mutation relative to said wild type copies of the genomic locus, to produce an amplified sample, where: i. the amplifying is done using a first primer and a second primer; and ii. the first primer comprises a 3′ terminal nucleotide that base pairs with the point mutation and also comprises a nucleotide sequence that is fully complementary to a sequence in the locus with the exception of a single base mismatch within 6 bases of the 3′ terminal nucleotide; and b) detecting the presence of said product in said amplified sample using a flap assay that employs an invasive oligonucleotide. A kit for performing the method is also provided.

Claim (Index 31):
The method of  claim 27 , wherein said sample is obtained from a human.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 93.0
- Lexical Diversity: 2.14474
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12946752', '14214508', '14228039', '14228058', '15165853']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6256947392995411
- 35 USC 102 Novelty (BERT): 0.5208503317511075
- Combined Prediction Score: 0.6152102985446978
- Mean Citation Score: 303.00064800000007
- Max Citation Score: 310.16574
- Similarity Product: 227.30450507920503

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test