PATENT CLAIM ANALYSIS

Application Number: 16260387
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["205", "775000"]

Abstract:
A method of detecting a state of a lipid membrane in a cell of a nanopore based sequencing chip is disclosed. A lipid membrane is coupled with an integrating capacitor, wherein the lipid membrane is between a working electrode and a counter electrode. An alternating current (AC) voltage is applied to the counter electrode. A voltage across the integrating capacitor is periodically sampled by an analog-to-digital converter (ADC). A change in the sampled voltage across the integrating capacitor in response to an intermediate change in the AC voltage is determined. A state of the lipid membrane is determined based on the determined change in the sampled voltage across the integrating capacitor in response to the intermediate change in the AC voltage.

Claim (Index 9):
The method of  claim 7 , wherein the timing of the pre-charging of integrating capacitors in the plurality of cells is configured such that the timing is after a frame of sequencing data from the plurality of cells has been read out, and wherein the frame is one frame prior to a frame when the AC voltage is switched to the intermediate monitoring magnitude.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 2.58824
- Patent Class: 205.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15715669', '15085700', '16186894', '15630342', '15085713']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7337166932821326
- 35 USC 102 Novelty (BERT): 0.6115142277661347
- Combined Prediction Score: 0.7214964467305328
- Mean Citation Score: 347.888724
- Max Citation Score: 547.5157
- Similarity Product: 490.3860098410309

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test