PATENT CLAIM ANALYSIS

Application Number: 16066402
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["549", "049000"]

Abstract:
The present invention relates to quinolin-2(1H)-one derivatives polymorph and its process thereof. Formula (I).

Claim (Index 18):
The process for the preparation of Brexpiprazole Hydrochloride, which comprises:\n a. reacting compound of formula V, with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone to obtain a compound of formula II; b. condensing the compound of formula II with compound of formula VI, wherein X, Lg represents a halogen atom or a group which causes a substitution reaction the same as in halogen atom to yield a compound of formula III; c. reacting the compound of formula XI, wherein X is a leaving group with piperazine compound of formula XII, to obtain a compound of formula XIII; d. treating the compound of formula XIII with anhydrous hydrogen chloride to yield a compound of formula IV; e. optionally desalifying compound of formula IV; f. condensing the compound of formula IV obtained as in step (d) or step (e) with formula III, wherein X is a leaving group to yield Brexpiprazole compound of formula I; and g. treating the obtained Brexpiprazole compound of formula I with anhydrous hydrogen chloride; and h. converting to Brexpiprazole hydrochloride.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 94.0
- Lexical Diversity: 1.15789
- Patent Class: 549.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14373163', '15764616', '15541568', '13995786', '10553399']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7102141633319948
- 35 USC 102 Novelty (BERT): 0.5058163519410128
- Combined Prediction Score: 0.6897743821928967
- Mean Citation Score: 237.167226
- Max Citation Score: 244.66219
- Similarity Product: 180.2735946915519

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test