PATENT CLAIM ANALYSIS

Application Number: 16014167
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "561000"]

Abstract:
The present application relates to combination treatments for bacterial infections. For example, the application relates to the use of one or more β-lactam antibiotics and one or more compounds of Formula I: (I) for treatment of a metallo-β-lactamase-expressing bacterial infection or a disease, disorder or condition arising from a metallo-β-lactamase-expressing bacterial infection.

Claim (Index 7):
A pharmaceutical composition comprising:\n one or more \u03b2-lactam antibiotic; and a compound being an aspergillomarasmine B (AM-B) represented by: or a lycomarasmine compound represented by: or a pharmaceutically acceptable salt and/or solvate thereof; and the one or more \u03b2-lactam antibiotic and the AM-B compound, lycomarasmine compound, or pharmaceutically acceptable salt and/or solvate thereof, are present in amounts that are effective for improving the efficacy of the one or more \u03b2-lactam antibiotic for the treatment of a bacterial infection or a disease, disorder or condition arising from a bacterial infection, wherein the one or more \u03b2-lactam antibiotic and the AM-B compound, lycomarasmine compound, or pharmaceutically acceptable salt and/or solvate thereof, are formulated in separate dosage forms, or the one or more \u03b2-lactam antibiotic and the AM-B compound, lycomarasmine compound, or pharmaceutically acceptable salt and/or solvate thereof, are formulated in a single dosage form, wherein the bacterial infection is an infection of at least one metallo-\u03b2-lactamase-expressing bacterium.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 94.0
- Lexical Diversity: 1.55263
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14888764', '15278916', '14694550', '15463952', '15516096']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7887598731692325
- 35 USC 102 Novelty (BERT): 0.6463602502267645
- Combined Prediction Score: 0.7745199108749856
- Mean Citation Score: 425.070208
- Max Citation Score: 614.0642
- Similarity Product: 599.6100680855035

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test