PATENT CLAIM ANALYSIS

Application Number: 16046254
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-07
Patent Classification: ["514", "210160"]

Abstract:
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

Claim (Index 1):
A compound of Formula I: or a pharmaceutically acceptable salt thereof; wherein: W is N or CR 5 ; X is N or CR 6 ; Y is N or CR 7 ; and Z is N or CR 8 ; provided not more than two of W, X, Y, and Z are N; R 1  is selected from H and C 1 -C 3  alkyl; R 2  is C 2 -C 3  alkylene optionally substituted with C 1 -C 2  haloalkyl or 3 or 4-membered cycloalkyl; R 3  and R 4 , together with the nitrogen atom to which they are attached, form:\n a 4, 5, 6, or 7-membered heteromonocyclic group, or \n a 6, 7, 8, 9, or 10-membered heterobicyclic group, \n each of which is optionally substituted with one to five substituents each independently selected from: C 1 -C 3  alkoxy, C 1 -C 3  alkyl, C 1 -C 3  haloalkoxy, C 1 -C 3  haloalkyl, 3 or 4-membered cycloalkoxy, 3 or 4-membered cycloalkyl, 3 or 4-membered heterocycloalkyl, carboxy, aryl, cyano, halo, and heteroaryl, wherein aryl and heteroaryl are optionally further substituted with one to five substituents each independently selected from C 1 -C 3  alkyl, C 1 -C 3  haloalkyl, and halo, \n provided that if R 3  and R 4 , together with the nitrogen atom to which they are attached, form a 5 or 6-membered heteromonocyclic group, then:\n i) R 2  is C 2 -C 3  alkylene substituted with C 1 -C 2  haloalkyl or 3 or 4-membered cycloalkyl, or \n ii) R 8  is halo or C 1 -C 3  alkyl, or \n iii) the 5 or 6-membered heteromonocyclic group is substituted with one to five substituents each independently selected from: C 1 -C 3  alkoxy, C 1 -C 3  alkyl, C 1 -C 3  haloalkoxy, C 1 -C 3  haloalkyl, 3 or 4-membered cycloalkoxy, 3 or 4-membered cycloalkyl, 3 or 4-membered heterocycloalkyl, carboxy, aryl, cyano, halo, and heteroaryl, wherein aryl and heteroaryl are optionally further substituted with one to five substituents each independently selected from C 1 -C 3 alkyl, C 1 -C 3  haloalkyl, and halo; and \n R 5 , R 6 , R 7  and R 8  are each independently selected from H, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, and halo.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 95.0
- Lexical Diversity: 1.1
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15148907', '15148884', '15041375', '13522044', '15630200']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8063574204683833
- 35 USC 102 Novelty (BERT): 0.565597380070106
- Combined Prediction Score: 0.7822814164285556
- Mean Citation Score: 371.179274
- Max Citation Score: 437.58426
- Similarity Product: 413.1721352369141

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test