PATENT CLAIM ANALYSIS

Application Number: 15983844
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "259300"]

Abstract:
Substituted pyrazolopyrimidines and dihydropyrazolopyrimidines and related compounds, their methods of manufacture, compositions containing these compounds, and methods of use of these compounds in treating lysosomal storage disorders such as Gaucher disease are described herein. The compounds are of general Formula (I) in which variables R 1 -R 7  and X are described in the application.

Claim (Index 38):
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein\n R 1  is pyrimidinyl) C 0 -C 4 alkyl, (C 3 -C 7 cycloalkyl)C 0 -C 4 alkyl, (pyrazolyl)C 0 -C 2 alkyl, (pyrrolyl)C 0 -C 2 alkyl, (imidazolyl)C 0 -C 2 alkyl, (thienyl)C 0 -C 2 alkyl, (oxazolyl)C 0 -C 2 alkyl, (thiazolyl)C 0 -C 2 alkyl, pyrolidinyl, naphthyl, quinolinyl, isoquinolinyl, tetrahydronaphthyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl tetrahydrofuranyl, morpholinyl, piperidinyl, or thiomorpholinyl, \n each of which is unsubstituted or substituted with one or more substituents independently chosen from halogen, hydroxyl, cyano, nitro, amino, \u2014CHO, \u2014COOH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkanoyl, mono- or di-C 1 -C 6 alkylamino, mono- or di-C 1 -C 6 alkylcarboxamide, C 1 -C 6 alkylester, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfonyl, C 1 -C 2 haloalkyl, and C 1 -C 2 haloalkoxy, and with 0 or 1 substituents chosen from Y\u2014Z\u2014 where Z is a covalent bond, C 1 -C 4 alkylene, \u2014S\u2014, \u2014O\u2014, \u2014NR\u2014, \u2014C(O)\u2014, \u2014NHC(O)\u2014, or \u2014C(O)NH\u2014, where R is hydrogen or C 1 -C 4 alkyl, and Y is phenyl or pyridyl, each of which is unsubstituted or substituted with 1 to 3 substituents independently chosen from halogen, hydroxyl, cyano, nitro, amino, C 1 -C 4 alkyl, and C 1 -C 4 alkoxy; \n R 2  is hydrogen or methyl; \n R 3  and R 6  are both hydrogen; and \n R 5  and R 7  are both methyl; or one of R 5  and R 7  is methyl and the other phenyl; or one of R 5  and R 7  is methyl and the other is difluoromethyl; \n with the proviso that R 1  is not unsubstituted cyclohexyl.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 93.0
- Lexical Diversity: 1.44186
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13991816', '15141275', '15359871', '15969864', '14997346']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7441023461148495
- 35 USC 102 Novelty (BERT): 0.5454625206739054
- Combined Prediction Score: 0.7242383635707551
- Mean Citation Score: 282.617564
- Max Citation Score: 376.4473
- Similarity Product: 278.05885806676747

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test