PATENT CLAIM ANALYSIS

Application Number: 16045358
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["544", "281000"]

Abstract:
This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Claim (Index 46):
The compound of  claim 1 , or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is H or C 1-6  alkyl; R 2  is OR 13 , C 6-10  aryl, 4-10 membered heterocycloalkyl, or 5-10 membered heteroaryl; wherein said C 6-10  aryl, 4-10 membered heterocycloalkyl, and 5-10 membered heteroaryl of R 2  are each optionally substituted with 1, 2, 3, 4, or 5 independently selected R j  substituents; each RR is independently selected from halo, CN, C 1-4  alkyl, C 1-4  haloalkyl, C 2-4  alkenyl, C 2-4  alkynyl, NHOR k , OR k , C(O)R k , C(O)NR k R k , C(O)OR k , OC(O)R k , OC(O)NR k R k , NHR k , NR k R k , NR k C(O)R k , S(O) 2 R k , NR k S(O) 2 R k , and S(O) 2 NR k R k ; R 3a  is selected from H, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 1-6  haloalkyl, C 6-10  aryl, C 3-10  cycloalkyl, 5-10 membered heteroaryl, 4-10 membered heterocycloalkyl, C 6-10  aryl-C 1-4  alkyl-, C 3-10  cycloalkyl-C 1-4  alkyl-, (5-10 membered heteroaryl)-C 1-4  alkyl-, (4-10 membered heterocycloalkyl)-C 1-4  alkyl-; wherein the C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 6-10  aryl, C 3-10  cycloalkyl, 5-10 membered heteroaryl, 4-10 membered heterocycloalkyl, C 6-10  aryl-C 1-4  alkyl-, C 3-10  cycloalkyl-C 1-4  alkyl-, (5-10 membered heteroaryl)-C 1-4  alkyl-, (4-10 membered heterocycloalkyl)-C 1-4  alkyl- of R 3a  are each optionally substituted by 1, 2, 3, or 4 independently selected R b  substituents; R 4a  is selected from H, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 1-6  haloalkyl, C 6-10  aryl, C 3 -10 cycloalkyl, 5-10 membered heteroaryl, 4-10 membered heterocycloalkyl, C 6-10  aryl-C 1-4  alkyl-, C 3-10  cycloalkyl-C 1-4  alkyl-, (5-10 membered heteroaryl)-C 1-4  alkyl-, (4-10 membered heterocycloalkyl)-C 1-4  alkyl-; wherein the C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 6-10  aryl, C 3-10  cycloalkyl, 5-10 membered heteroaryl, 4-10 membered heterocycloalkyl, C 6-10  aryl-C 1-4  alkyl-, C 3-10  cycloalkyl-C 1-4  alkyl-, (5-10 membered heteroaryl)-C 1-4  alkyl-, (4-10 membered heterocycloalkyl)-C 1-4  alkyl- of R 4a  are each optionally substituted by 1, 2, 3, or 4 independently selected R b  substituents; R 3  is H or C 1-6  alkyl; R 4  is H or C 1-6  alkyl; R 5  is H, halo, C 1-6  alkyl, or C 1-6  haloalkyl; R 5a  is H or C 1-6  alkyl; R 6  is H, halo, CN, C 1-6  alkyl, or C 1-6  haloalkyl; and R 7  is H, halo, CN, C 1-4  alkyl or C 1-4  haloalkyl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 95.0
- Lexical Diversity: 1.27778
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15343375', '15631417', '13085643', '13329532', '14872881']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.825177538859975
- 35 USC 102 Novelty (BERT): 0.6052160435709144
- Combined Prediction Score: 0.803181389331069
- Mean Citation Score: 421.74511
- Max Citation Score: 495.84445
- Similarity Product: 415.4512396047712

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test