PATENT CLAIM ANALYSIS

Application Number: 16163480
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "653000"]

Abstract:
The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-norepinephrine and exhibit less than 5% degradation of total norepinephrine.

Claim (Index 1):
A method of treating hypotension, comprising:\n administering a ready-to-administer norepinephrine composition at an initial dose per minute; administering the norepinephrine composition at a maintenance dose per minute, wherein the initial dose per minute is greater than the maintenance dose per minute; wherein the initial dose per minute is a dose of between 8 and 12 \u03bcg/min, and wherein the maintenance dose per minute is a dose of between 2 and 4 \u03bcg/min; wherein the norepinephrine composition comprises norepinephrine or a salt thereof in an aqueous acidic solution having a pH range of between 3.7 and 4.3, wherein the aqueous acidic solution further comprises a chelating agent and a tonicity agent; and wherein the norepinephrine composition is substantially free of antioxidants.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.2973
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16163476', '15883798', '15949736', '14837749', '15976279']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.792918243759813
- 35 USC 102 Novelty (BERT): 0.5763895711915303
- Combined Prediction Score: 0.7712653765029848
- Mean Citation Score: 394.381054
- Max Citation Score: 520.6588
- Similarity Product: 376.5750898159266

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test