PATENT CLAIM ANALYSIS

Application Number: 15748905
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["544", "281000"]

Abstract:
The present invention concerns novel fused pyrimidinone and triazinone derivatives containing bridged nitrogen, their process of preparation and their use as antifungal or antiparasitic agents.

Claim (Index 6):
A compound according to  claim 1  chosen from\n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]imidazo[1,2-c]pyrimidin-5-one (27) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-methylimidazo[1,2-c]pyrimidin-5-one (28) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-phenylimidazo[1,2-c]pyrimidin-5-one (29) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(4-fluorophenyl)imidazo[1,2-c]pyrimidin-5-one (30) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(4-chlorophenyl)imidazo[1,2-c]pyrimidin-5-one (31) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(4-bromophenyl)imidazo[1,2-c]pyrimidin-5-one (32) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-[(4-trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-one (33) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(4-cyanophenyl)imidazo[1,2-c]pyrimidin-5-one (34) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(4-nitrophenyl)imidazo[1,2-c]pyrimidin-5-one (35) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-2-(thiazol-2-yl)imidazo[1,2-c]pyrimidin-5-one (36) \n Ethyl-6-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-5-oxo-imidazo[1,2-c]pyrimidine-2-carboxylate (37) \n 6-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-5-oxo-imidazo[1,2-c]pyrimidine-2-carbonitrile (38) \n 3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (44) \n 7-Bromo-3-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (45) \n 3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-4-oxo-3,4-dihydro-pyrrolo[1,2-d][1,2,4]triazine-7-carbonitrile (46) \n 3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-7-phenyl-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (47) \n 7-(4-Chlorophenyl)-3-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (48) \n 4-{3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-4-oxo-3,4-dihydro-pyrrolo[1,2-d][1,2,4]triazin-7-yl}benzonitrile (49) \n 3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-7-(4-nitrophenyl)-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (50) \n 3-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-7-(4-methoxyphenyl)-3H-pyrrolo[1,2-d][1,2,4]triazin-4-one (51) \n or one of their pharmaceutically acceptable salts.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.08
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10647023', '15841902', '16066763', '13578590', '12970297']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8012224854373305
- 35 USC 102 Novelty (BERT): 0.5520473506912191
- Combined Prediction Score: 0.7763049719627194
- Mean Citation Score: 392.91976000000005
- Max Citation Score: 411.02176
- Similarity Product: 338.8300014154434

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test