PATENT CLAIM ANALYSIS

Application Number: 15972943
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-03
Patent Classification: ["424", "468000"]

Abstract:
A once-a-day controlled release oral dosage form of methazolamide is provided. The dosage form comprises a therapeutically effective amount of methazolamide and a high molecular weight binder. The dosage is configured for once-daily administration to a subject in need thereof, and releases methazolamide over a period of about twenty-four hours.

Claim (Index 1):
A once-a-day controlled release oral dosage form comprising:\n a drug selected from a methazolamide, a methazolamide analog, a methazolamide prodrug, a methazolamide derivative, or a combination thereof; and a high molecular weight binder, wherein the dosage form provides an in vitro release of from about 50% to about 80% by weight of the drug at 12 hours when measured by the USP Paddle Method at 100 rpm in acetate buffer (pH=4.5), wherein the dosage form provides an in vitro release of about 90% or greater by weight of the drug at 24 hours when measured by the USP Paddle Method at 100 rpm in acetate buffer (pH=4.5) and wherein the drug has a particle size distribution as follows: a D(v, 0.1) of about 1 \u03bcm to 100 \u03bcm, a D(v, 0.5) of about 100 \u03bcm to 150 \u03bcm, and a D(v, 0.9) of about 200 \u03bcm to 300 \u03bcm.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 93.0
- Lexical Diversity: 1.38462
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15621298', '12499034', '12378586', '12914054', '10569862']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7434136352203611
- 35 USC 102 Novelty (BERT): 0.5664095508790079
- Combined Prediction Score: 0.7257132267862257
- Mean Citation Score: 294.003498
- Max Citation Score: 471.50354
- Similarity Product: 372.8759764169466

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test