PATENT CLAIM ANALYSIS

Application Number: 15862527
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["435", "440000"]

Abstract:
The invention relates to methods, uses, systems, arrays, engineered nucleotide sequences and vectors for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for treatment of microbes such as for environmental, medical, food and beverage use. The invention relates inter alia to methods of controlling microbiologically influenced corrosion (MIC) or biofouling of a substrate or fluid in an industrial or domestic system.

Claim (Index 3):
The method of  claim 1 , wherein the method comprising:\n (a) contacting the mixed gut bacterial population with an engineered nucleic acid for producing a host modifying crRNA (HM-crRNA), and (b) producing the HM-crRNA in the host cells; wherein: (i) the HM-crRNA is operable with a Cas in the host cells, wherein the engineered nucleic acid and the Cas are comprised by a HM-CRISPR/Cas system in the host cells; and (ii) the HM-crRNA comprises a nucleotide sequence that is capable of hybridizing to a target sequence in the host cells to guide the Cas to modify the target sequence in the host cells, wherein the host cells are killed or growth of the host cells is reduced, thereby increasing the relative ratio of the  Bacteroides  bacteria versus the second bacterial sub-population in the mixed gut bacterial population.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 86.0
- Lexical Diversity: 1.54839
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15160405', '15460962', '15817135', '15817139', '15817125']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.749430303785219
- 35 USC 102 Novelty (BERT): 0.6350797830727328
- Combined Prediction Score: 0.7379952517139704
- Mean Citation Score: 596.3379140000002
- Max Citation Score: 620.957
- Similarity Product: 560.7375675389766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test