PATENT CLAIM ANALYSIS

Application Number: 15892302
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "212070"]

Abstract:
The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Claim (Index 16):
A pharmaceutical composition comprising a therapeutically effective amount of at least one compound having a structure represented by a formula selected from: wherein each of Q 1  and Q 2  is independently selected from CH 2 , CH(OH), and C(O), provided that at least one of Q 1  and Q 2  is C(O); wherein Z is selected from CH 2  and NH; wherein each of R 1a  and R 1b  is independently selected from hydrogen and \u2014F; wherein R 2  is selected from hydrogen, halogen, \u2014CN, \u2014(CH 2 ) n OR 20 , and \u2014OC(O)R 21 ;\n wherein n is selected from 0, 1, 2, 3, and 4; \n wherein R 20 , when present, is selected from hydrogen, C1-C4 alkyl, C1-C4 haloalkyl, Ar 1 , and \u2014(C1-C4 alkyl)Ar 1 ;\n wherein Ar 1 , when present, is selected from C5-C6 aryl and C4-C5 heteroaryl and substituted with 0, 1, 2, or 3 groups independently selected from halogen, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 hydroxyalkyl, and C1-C4 alkoxy; \n \n wherein R 21 , when present, is selected from hydrogen, C1-C4 alkyl, C1-C4 haloalkyl, and Ar 1 ; \n wherein R 3  is selected from hydrogen and C1-C4 alkyl; and wherein each of R 4a , R 4b , R 4c , and R 4d  is independently selected from hydrogen, halogen, \u2014CO 2 H, \u2014CN, \u2014OH, \u2014NH 2 , C1-C8 alkyl, C1-C8 haloalkyl, C1-C8 alkylnitrile, C1-C8 hydroxyalkyl, C1-C8 alkoxy, C1-C8 halohydroxyalkyl, C1-C8 aminoalkyl, C1-C8 alkylamino, (C1-C8)(C1-C8) dialkylamino, and Cy 2 ;\n wherein Cy 2 , when present, is selected from C3-C5 cycloalkyl, C2-C5 heterocycloalkyl, C5-C6 aryl, and C4-C5 heteroaryl and substituted with 0, 1, 2, or 3 groups independently selected from halogen, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 hydroxyalkyl, and C1-C4 alkoxy; and \n wherein Cy 1  is selected from C3-C10 cycloalkyl, C5-C6 aryl, and C4-C5 heteroaryl and substituted with 0, 1, or 2 groups independently selected from halogen, \u2014CO 2 H, \u2014CN, \u2014OH, \u2014NH 2 , C1-C8 alkyl, C1-C8 haloalkyl, C1-C8 alkylnitrile, C1-C8 hydroxyalkyl, C1-C8 alkoxy, C1-C8 halohydroxyalkyl, C1-C8 aminoalkyl, C1-C8 alkylamino, (C1-C8)(C1-C8) dialkylamino, and Cy 2 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.42308
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14380659', '14913266', '15039763', '15283508', '13329025']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7812120425066209
- 35 USC 102 Novelty (BERT): 0.5549155665672941
- Combined Prediction Score: 0.7585823949126883
- Mean Citation Score: 415.690416
- Max Citation Score: 428.13474
- Similarity Product: 303.0167865857792

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test