PATENT CLAIM ANALYSIS

Application Number: 15978390
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["424", "135100"]

Abstract:
The present invention relates to bispecific constructs that specifically bind to immune effector cells and, simultaneously, to IL23R-carrying target cells, as well as nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production and use thereof, including such bispecific constructs for use in treating inflammatory and/or autoimmune diseases and/or cancer.

Claim (Index 12):
The method of  claim 11 , wherein the bispecific scDb comprises two variable heavy chain domains (V H ) or fragments thereof and two variable light chain domains (V L ) or fragments thereof connected by linkers L1, L2 and L3 in the order V H A-L1-V S B-L2-V H B-L3-V L A, V H A-L1-V H B-L2-V S B-L3-V L A, V L A-L1-V S B-L2-V H B-L3-V H A, V L A-L1-V H B-L2-V S B-L3-V H A, V H B-L1-V L A-L2-V H A-L3-V S B, V H B-L1-V H A-L2-V L A-L3-V S B, V S B-L1-V L A-L2-V H A-L3-V H B or V S B-L1-V H A-L2-V L A-L3-V H B, wherein the V L A and V H A domains jointly form the antigen binding site for CD3\u03b5, and V S B and V H B jointly form the antigen binding site for IL23R.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 93.0
- Lexical Diversity: 1.42857
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14889225', '15829783', '15604153', '15225107', '15829793']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7096728156721012
- 35 USC 102 Novelty (BERT): 0.605192379694692
- Combined Prediction Score: 0.6992247720743603
- Mean Citation Score: 362.187456
- Max Citation Score: 680.0639
- Similarity Product: 419.27793244975214

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test