PATENT CLAIM ANALYSIS

Application Number: 16220267
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "284000"]

Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Claim (Index 1):
A compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, wherein:\n A is optionally substituted aryl or optionally substituted heteroaryl; \n B is selected from the group consisting of hydrogen, halo, CN, optionally substituted \u2014C 1 -C 6  alkyl, and optionally substituted \u2014C 3 -C 6  cycloalkyl; \n X is optionally substituted aryl or optionally substituted heteroaryl; \n Alternatively, B and X are taken together with the carbon atom to which they are attached to form an additional optionally substituted C 4 -C 12  cycloalkenyl or optionally substituted 4- to 12-membered heterocyclic; \n Y is optionally substituted aryl or optionally substituted heteroaryl; \n Z is selected from the group consisting of hydrogen, optionally substituted \u2014C 1 -C 12  alkyl, optionally substituted \u2014C 2 -C 12  alkenyl, optionally substituted \u2014C 2 -C 12  alkynyl, optionally substituted \u2014C 3 -C 8  cycloalkyl, optionally substituted 3- to 8-membered heterocyclic, optionally substituted aryl and optionally substituted heteroaryl, \u2014C(O)NR 1 R 2 , and \u2014C(O)OR 1 ; \n R 1  and R 2  at each occurrence are each independently selected from the group consisting of hydrogen, optionally substituted \u2014C 1 -C 8  alkyl, optionally substituted \u2014C 2 -C 8  alkenyl, optionally substituted \u2014C 2 -C 8  alkynyl, optionally substituted \u2014C 3 -C 8  cycloalkyl, optionally substituted 3- to 8-membered heterocyclic, optionally substituted aryl and optionally substituted heteroaryl; \n Alternatively, R 1  and R 2  are taken together with the nitrogen atom to which they are attached form an optionally substituted 3- to 12-membered heterocyclic; \n R is selected from the group consisting of optionally substituted \u2014C 1 -C 8  alkyl, optionally substituted \u2014C 2 -C 8  alkenyl, optionally substituted \u2014C 2 -C 8  alkynyl; \n Alternatively, R and Z are taken together with the atoms to which they are attached to form an additional optionally substituted 4- to 12-membered heterocyclic; and \n Alternatively, R and A are taken together with the atoms to which they are attached to form an additional optionally substituted 5- to 7-membered heterocyclic.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 98.0
- Lexical Diversity: 1.72131
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16210472', '15209150', '15421777', '15617445', '15216124']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8364576602918775
- 35 USC 102 Novelty (BERT): 0.5417790709281445
- Combined Prediction Score: 0.8069898013555042
- Mean Citation Score: 371.363898
- Max Citation Score: 383.03064
- Similarity Product: 358.4727264917708

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test