PATENT CLAIM ANALYSIS

Application Number: 15767551
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["435", "205000"]

Abstract:
The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Claim (Index 3):
A glucoamylase variant, comprising a substitution at one or more positions selected from the group consisting of: Q1, S2, V3, D4, S5, S8, S9, G11, I13, K15, A16, V18, L19, N25, S27, S30, A32, A34, V36, V37, S44, S57, V59, F60, Y67, T68, I71, D72, S73, T74, S75, S76, L77, R78, D82, D83, F84, V85, T86, N90, L91, Q93, S95, L101, T102, T103, S134, L137, T139, N142, L145, S146, N147, Y152, V153, T154, S155, L157, W158, P159, I160, Q162, N163, S170, S175, T176, Y177, S186, R199, A202, A203, T206, Q210, T211, S212, Q213, S215, Q220, A221, D222, N223, L224, F227, P234, S235, Y238, T240, T243, G244, G245, G246, S248, A252, T254, L255, A270, A271, K279, S282, L284, Y295, S296, I297, N298, S299, G300, A302, S303, N304, S316, G319, T326, V330, N339, E342, S343, Q344, E348, S351, Q359, S362, G363, T365, A366, S371, S372, T378, S381, I383, F386, A392, N394, K396, N401, K410, D412, S414, S417, V419, D420, E433, N437, T438, Q439, F440, G442, A446, N470, E472, V474, W475, N478, S484, V485, D486, A487, S492, A493, D494, N495, S501, A502, I509, T510, N512, S516, A518, I519, N527, A530, E534, P537, N538, N539, I541, A545, S546, G547, N552, and T554, wherein the positions correspond to amino acid positions in the amino acid sequence set forth in SEQ ID NO: 3; and wherein the substitution at the one or more positions provides a glucoamylase variant having an increase in specific activity measured as improvement factor, IF, of at least 1.1, and further wherein the variants have at least at least 85%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 91.0
- Lexical Diversity: 1.89394
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14787418', '14901953', '14426051', '14773673', '15112096']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6151371314761349
- 35 USC 102 Novelty (BERT): 0.548879929334962
- Combined Prediction Score: 0.6085114112620177
- Mean Citation Score: 367.950342
- Max Citation Score: 422.01895
- Similarity Product: 284.13636555140613

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test