PATENT CLAIM ANALYSIS

Application Number: 16138369
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "252030"]

Abstract:
The present invention aims to provide a compound having a TrkA inhibitory action, a pharmaceutically acceptable salt thereof, or a solvate thereof, a pharmaceutical composition containing the same as an active ingredient, and a preventive and/or therapeutic agent for medicinal use, in particular for a disease in which TrkA in involved (pain, cancers, inflammation/inflammatory diseases, allergic diseases, skin diseases, neurodegenerative diseases, infectious diseases, Sjogren's syndrome, endometriosis, renal diseases, osteoporosis, and the like). Specifically, the present invention provides a compound or an optical isomer thereof, a pharmaceutically acceptable salt thereof, a solvate thereof, or the like, the compound represented by formula (I):

Claim (Index 1):
A compound or an optical isomer thereof, a pharmaceutically acceptable salt thereof, or a solvate thereof, the compound represented by the following formula (I-a-1): where R 1a  and R 1b  are each independently a hydrogen, a halogen atom, a cyano group, a C 1-6  alkyl group, a halogenated C 1-6  alkyl group, a hydroxy C 1-6  alkyl group, a cyanated C 1-6  alkyl group, a C 1-6  alkoxy group, a halogenated C 1-6  alkoxy group, a C 1-6  alkoxy C 1-6  alkyl group, a mono-/di-C 2-7  alkanoyl amino group, a carboxamide group, or a C 1-6  alkoxy carbonyl group;\n R 3  is a hydrogen atom, a halogen atom, a C 1-6  alkyl group, a C 3-8  cycloalkyl group, a halogenated C 1-6  alkyl group, a hydroxy C 1-6  alkyl group, a C 6-10  aryl group, a 5- or 6-membered heteroaryl group, or a non-aromatic heterocyclic group in which the C 6-10  aryl group, the 5- or 6-membered heteroaryl group, and the non-aromatic heterocyclic group may each have 1 to 3 substituent groups selected from a halogen atom and a C 1-6  alkyl group; \n the ring B is a C 6-10  aryl group or a 5- or 6-membered heteroaryl group; \n q is an integer of 0, 1, 2, or 3; and \n R 5  is a hydrogen atom, a hydroxyl group, a cyano group, a halogen atom, a C 1-6  alkyl group, a halogenated C 1-6  alkyl group, a hydroxy C 1-6  alkyl group, a C 3-8  cycloalkyl group, a C 1-6  alkoxy group, a halogenated C 1-6  alkoxy group, a C 2-6  alkanoyl group, a C 1-6  alkylsulfonyl group, a \u2014CONR \u03b1 R \u03b2  group in which the R \u03b1  and R \u03b2  are each independently a hydrogen, a C 1-6  alkyl group, a halogenated C 1-6  alkyl group, or a C 3-8  cycloalkyl group; or a carboxamide group.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 97.0
- Lexical Diversity: 1.89706
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11988659', '13392350', '13008456', '14442609', '14601775']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7677915617541665
- 35 USC 102 Novelty (BERT): 0.5253008016268976
- Combined Prediction Score: 0.7435424857414397
- Mean Citation Score: 301.63904999999994
- Max Citation Score: 317.48358
- Similarity Product: 245.7629624251056

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test