PATENT CLAIM ANALYSIS

Application Number: 15940206
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "371000"]

Abstract:
The present disclosure provides compounds, compositions and method targeting GPER for the treatment of disorders and disease such as cancers, gallstone disease and for neuroprotection. In some aspects, the present disclosure provides compounds of the formula: wherein the variables are as defined herein for the treatment of disease including cancers, hormonal cancers, breast cancers including triple negative breast cancer, and leukemias.

Claim (Index 2):
The method of  claim 1 , wherein the compound is further defined as: wherein:\n Y 1  is \u2014X 3 -A-X 4 \u2014; wherein:\n X 3  and X 4  are each independently a covalent bond, alkanediyl (C\u22646) , or substituted alkanediyl (C\u22646) ; and \n A is \u2014C(O)\u2014, \u2014OC(O)\u2014, \u2014C(O)O\u2014, \u2014NR a C(O)\u2014, \u2014C(O)NR a \u2014, \u2014S(O) 2 \u2014, \u2014NR a S(O) 2 \u2014, or \u2014S(O) 2 NR a \u2014, wherein:\n R a  is hydrogen, alkyl (C\u22646) , or substituted alkyl (C\u22646) ; \n \n \n R 1  is hydrogen, amino, halo, or hydroxy; \n n is 0, 1, 2, 3, 4, or 5; \n R 2  and R 3  are each independently hydrogen or alkyl (C\u226412) , cycloalkyl (C\u226412) , aryl (C\u226412) , or a substituted version of these three groups; or R 2  and R 3  are taken together and are alkanediyl (C\u22648) , alkenediyl (C\u22648) , or a substituted version of either of these groups; and \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 90.0
- Lexical Diversity: 1.75
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15327912', '15740656', '15557288', '15677959', '14911881']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8007816344293798
- 35 USC 102 Novelty (BERT): 0.5108332917225584
- Combined Prediction Score: 0.7717868001586977
- Mean Citation Score: 280.981738
- Max Citation Score: 290.10852
- Similarity Product: 219.242095939579

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test