PATENT CLAIM ANALYSIS

Application Number: 15972953
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "197110"]

Abstract:
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of  Streptococcus pneumoniae  (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection.

Claim (Index 1):
A process for preparing a multivalent immunogenic composition comprising:\n (a) individually purifying polysaccharides from  Streptococcus pneumoniae  serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F; (b) chemically activating the individual purified polysaccharides; (b) separately conjugating the activated polysaccharides to a carrier protein to form individual glycoconjugates; (c) purifying the individual glycoconjugates; and (d) compounding the purified glycoconjugates to formulate the multivalent immunogenic composition; wherein the chemical activation of at least one of the purified polysaccharides for  S. pneumoniae  serotypes comprises hydrolysis of the polysaccharide with hydrochloric acid, and wherein the carrier protein is CRM 197 .

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 1.41892
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14322057', '13439111', '12357853', '15042189', '11644095']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7886057183887358
- 35 USC 102 Novelty (BERT): 0.6038478384685848
- Combined Prediction Score: 0.7701299303967208
- Mean Citation Score: 589.1149280000002
- Max Citation Score: 591.4125
- Similarity Product: 447.512943276018

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test