PATENT CLAIM ANALYSIS

Application Number: 15747952
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["548", "143000"]

Abstract:
The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.

Claim (Index 5):
The 1,3,4-oxadiazole sulfonamide derivative compound represented by formula I, stereoisomer thereof or pharmaceutically acceptable salt thereof according to  claim 1 , wherein the compound represented by formula I is selected from the group consisting of compounds described in the following table: Ex. Comp. Structure 1 11044   2 11045     3 11078   4 11088   5 11089   6 11120   7 11121   8 11128   9 11129   10 11133   11 11151   12 11152   13 11153   14 11154   15 11155   16 11156   17 11167   18 11168   19 11169   20 11170   21 11171   22 11172   23 11173   24 11174   25 11175   26 11176   27 11177   28 11178   29 11179   30 11180   31 11181   32 11182   33 11183   34 11184   35 11186   36 11190   37 11191   38 11192   39 11193   40 11194   41 11195   42 11196   43 11197   44 11216   45 11217   46 11218   47 11219   48 11220   49 11221   50 11222   51 11225   52 11226   53 11227   54 11229   55 11230   56 11231   57 11248   58 11249   59 11250   60 11251   61 11252   62 11253   63 11254   64 11255   65 11256   66 11271   67 11272   68 11273   69 11274   70 11275   71 11276   72 11277   73 11278   74 11279   75 11280   76 11281   77 11282   78 11283   79 11284   80 11287   81 11288   82 11289   83 11290   84 11291   85 11292   86 11323   87 11324   88 11338   89 11345   90 11346   91 11347   92 11348   93 11350   94 11351   95 11352   96 11353   97 11354   98 11355   99 11366   100 11367   101 11368   102 11372   103 11373   104 11377   105 11386   106 11387   107 11388   108 11389   109 11390   110 11392   111 11402   112 11403   113 11404   114 11405   115 11406   116 11411   117 11412   118 11426   119 11427   120 11428   121 11429   122 11430   123 11431   124 11432   125 11433   126 11447   127 11448   128 11451   129 11452   130 11460   131 11461   132 11462   133 11463   134 11497   135 11501   136 11502   137 11503   138 11504   139 11505   140 11506    141 11507   142 11508   143 11514   144 11518   145 11520   146 11521   147 11522   148 11539   149 11540   150 11541   151 11552   152 11553   153 11554   154 11564   155 11565   156 11566   157 11567   158 11573   159 11582   160 11583   161 11588   162 11589   163 11605   164 11606   165 11625   166 11628   167 11629   168 11630   169 11631   170 11632   171 11633   172 11634   173 11636   174 11637   175 11638   176 11639   177 11645   178 11646   179 11647   180 11648   181 11655   182 11656   183 11657   184 11658   185 11663   186 11665   187 11668   188 11669   189 11675   190 11676   191 11677   192 11678   193 11679   194 11680   195 11681   196 11682   197 11683   198 11684   199 11685   200 11686   201 11687   202 11688   203 11689   204 11690   205 11691   206 11692   207 11693   208 11694   209 11695   210 11696   211 11697   212 11698   213 11699   214 11700   215 11705   216 11706   217 11707   218 11708   219 11709   220 11710   221 11711   222 11712   223 11717   224 11718   225 11719   226 11721   227 11722   228 11723   229 11724   230 11725   231 11726   232 11727   233 11728   234 11729   235 11730   236 11731   237 11732   238 11733   239 11734   240 11735   241 11736   242 11737   243 11738   244 11739   245 11740   246 11741   247 11742   248 11743   249 11744   250 11745   251 11746   252 11747   253 11748   254 11749   255 11750   256 11751   257 11752   258 11753   259 11754   260 11755   261 11756   262 11757   263 11758   264 11759   265 11760   266 11761   267 11762   268 11763   269 11764   270 11765   271 11766   272 11767   273 11768   274 11769   275 11770   276 11771   277 11772   278 11773   279 11774   280 11775   281 11776   282 11777   283 11778   284 11779   285 11780   286 11781   287 11782   288 11783   289 11784   290 11785   291 11786   292 11790   293 11791   294 11792   295 11793   296 11794   297 11795   298 11796   299 11797   300 11798   301 11799   302 11800   303 11801   304 11802   305 11803   306 11804   307 11805   308 11806   309 11807   310 11808   311 11809   312 11810   313 11811   314 11812   315 11813   316 11814   317 11815   318 11816   319 11817   320 11818   321 11819   322 11820   323 11821   324 11822   325 11836   326 11837   327 11838   328 11839   329 11840   330 11841   331 11842   332 11843   333 11844   334 11845   335 11847   336 11848   337 11849

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.82143
- Patent Class: 548.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15747850', '15748081', '15763972', '13093729', '14099276']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7968513534463664
- 35 USC 102 Novelty (BERT): 0.5506746684706503
- Combined Prediction Score: 0.7722336849487947
- Mean Citation Score: 349.8987160000001
- Max Citation Score: 412.90927
- Similarity Product: 403.8812014648497

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test