PATENT CLAIM ANALYSIS

Application Number: 15995586
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["424", "722000"]

Abstract:
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein L, X, R a , R b , R 1 , R 2  and R 3  are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Claim (Index 1):
A method of treating a disease, disorder, or condition in a subject comprising:\n (a) administering to the subject a compound of formula (I): wherein R 1  represents a 5- or 6-membered heteroaryl group optionally substituted by at least one substituent selected from halogen, cyano, hydroxyl, C 3 -C 6  cycloalkyl, C 1 -C 3  alkyl, C 1 -C 3  alkoxy, C 1 -C 3  alkoxycarbonyl, C 1 -C 3  alkoxycarbonylamino, C 1 -C 3  haloalkyl, C 1 -C 3  haloalkoxy, \u2014NR 4 R 5 , C 3 -C 6  cycloalkylamino, C 1 -C 3  alkylcarbonyloxy, C 1 -C 3  alkylcarbonylamino, sulphonamido, C 1 -C 3  alkylsulphonyl, C 1 -C 3  alkylsulphonylamino and \u2014C(O)NR 6 R 7 ; L represents a bond, CH 2 , O or NR 12 ; R a  represents a hydrogen atom or a C 1 -C 3  alkyl or C 1 -C 3  haloalkyl group; R b  represents a hydrogen atom or a C 1 -C 3  alkyl or C 1 -C 3  haloalkyl group; X represents CH 2 , CHF or CF 2 ; R 2  represents a hydrogen atom or a C 1 -C 6  alkyl or C 3 -C 6  cycloalkyl group; R 3  represents a phenyl group or a 5- or 6-membered heteroaryl group, all optionally substituted by at least one substituent independently selected from halogen, hydroxyl, cyano, C 1 -C 3  alkyl, C 1 -C 3  haloalkyl, C 1 -C 3  hydroxyalkyl, C 1 -C 3  alkoxy, C 1 -C 3  haloalkoxy, C 2 -C 4  alkenyl, C 1 -C 3  alkylcarbonyloxy, C 1 -C 3  alkoxycarbonyl, \u2014NR 8 R 9 , \u2014C(O)NR 10 R 11 , C 3 -C 6  cycloalkyl, C 3 -C 6  cycloalkyloxy, C 3 -C 6  cycloalkylmethyl or a 5- or 6-membered heteroaryl group, the heteroaryl group itself being optionally substituted by at least one substituent independently selected from C 1 -C 6  alkyl, C 1 -C 6  alkoxy and C 1 -C 6  haloalkoxy; R 4  and R 5  each independently represent a hydrogen atom or a C 1 -C 3  alkyl or C 3 -C 6  cycloalkyl group, or R 4  and R 5  may together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring optionally substituted by at least one substituent independently selected from halogen, hydroxyl and C 1 -C 3  alkoxy; R 6  and R 7  each independently represent a hydrogen atom or a C 1 -C 3  alkyl or C 3 -C 6  cycloalkyl group, or R 6  and R 7  may together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring optionally substituted by at least one substituent independently selected from halogen and hydroxyl; R 8  and R 9  each independently represent a hydrogen atom or a C 1 -C 3  alkyl or C 3 -C 6  cycloalkyl group, or R 8  and R 9  may together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring optionally substituted by at least one substituent independently selected from halogen, hydroxyl and C 1 -C 3  alkoxy; R 10  and R 11  each independently represent a hydrogen atom or a C 1 -C 3  alkyl or C 3 -C 6  cycloalkyl group, or R 10  and R 11  may together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring optionally substituted by at least one substituent independently selected from halogen and hydroxyl; and R 12  represents a hydrogen atom, methyl group or a C 2 -C 3  alkylene chain that links to R 1  to form a 5- or 6-membered ring; or enantiomers thereof or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 94.0
- Lexical Diversity: 1.35714
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14625812', '15120048', '15029356', '15320887', '15120002']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8440230178624324
- 35 USC 102 Novelty (BERT): 0.7108843418967722
- Combined Prediction Score: 0.8307091502658664
- Mean Citation Score: 675.908338
- Max Citation Score: 867.8966
- Similarity Product: 747.928420423174

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test