PATENT CLAIM ANALYSIS

Application Number: 15990561
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "093210"]

Abstract:
Provided herein are modified T lymphocytes comprising chimeric receptors and methods of use thereof.

Claim (Index 93):
A modified T lymphocyte comprising:\n a. a first polypeptide comprising a first extracellular antigen binding domain that binds a first antigen, and a T cell survival motif, wherein said first polypeptide does not comprise an intracellular signaling domain or a co-stimulatory motif; and b. a second polypeptide comprising a second extracellular antigen binding domain that binds a second antigen, an intracellular signaling domain and one or more co-stimulatory motifs; wherein said modified lymphocyte survives only when said T cell survival motif and said intracellular signaling domain are both activated by said first antigen and said second antigen, respectively.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 93.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14653650', '14775891', '15550645', '14873836', '14516880']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7251031327540891
- 35 USC 102 Novelty (BERT): 0.5590598518253374
- Combined Prediction Score: 0.708498804661214
- Mean Citation Score: 390.335344
- Max Citation Score: 464.99088
- Similarity Product: 290.46467457707405

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test