PATENT CLAIM ANALYSIS

Application Number: 16201784
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "04400R"]

Abstract:
In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Claim (Index 9):
The method of  claim 7 , wherein the tumor cells comprise breast cancer cells, cervical cancer cells, lung cancer cells, bladder cancer cells, ovarian cancer cells, esophageal cancer cells, head and neck cancer cells, kidney cancer cells, glioma cells, bladder cancer cells, pancreatic cancer cells, colon cancer cells, or a combination thereof.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 98.0
- Lexical Diversity: 2.61017
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14323840', '13081319', '14738337', '15726851', '14438172']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7476491715182513
- 35 USC 102 Novelty (BERT): 0.6321988001756843
- Combined Prediction Score: 0.7361041343839946
- Mean Citation Score: 356.35071600000015
- Max Citation Score: 576.9007
- Similarity Product: 536.0505906140567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test