PATENT CLAIM ANALYSIS

Application Number: 15766821
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-02
Patent Classification: ["424", "135100"]

Abstract:
The present disclosure relates to methods for treating various rare genetic disorders which are characterized, in part, by abnormal resistance to insulin and/or hyperglycemia using a glucagon receptor blocking agent. In various embodiments, the present disclosure relates to methods for treating a rare genetic disorder using antigen binding and antagonizing proteins, e.g., fully human antibodies, that specifically bind to and antagonize the function of the human glucagon receptor.

Claim (Index 29):
A method according to  claim 25 , wherein the fully human antagonistic antibody comprises a heavy chain variable region having the amino acid sequence selected from the group consisting of SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 27, and SEQ ID NO: 28 and comprises a light chain variable region having the amino acid sequence selected from the group consisting of SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 31, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, SEQ ID NO: 41, SEQ ID NO: 42, SEQ ID NO: 43, SEQ ID NO: 44, SEQ ID NO: 45, SEQ ID NO: 46, and SEQ ID NO: 47.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 1.52
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316866', '13900275', '14855274', '15415672', '13301944']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8041071249990591
- 35 USC 102 Novelty (BERT): 0.5238826376743971
- Combined Prediction Score: 0.7760846762665929
- Mean Citation Score: 339.65670200000005
- Max Citation Score: 344.82382
- Similarity Product: 255.4750080676293

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test