PATENT CLAIM ANALYSIS

Application Number: 16037375
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["544", "317000"]

Abstract:
Disclosed are a compound and a pharmaceutical composition that exhibit an excellent drug efficacy against a tumor, in particular a tumor which has acquired resistance to gemcitabine. Specifically, provided is a thionucleoside derivative represented by General (in the formula, R 1  represents a hydroxyl group which may be protected, a C 1-20  alkoxy group which may be substituted, or the like; R 2  represents a C 1-20  alkoxy group which may be substituted, a C 3-8  cycloalkoxy group which may be substituted, or the like; and R 3  represents a hydrogen atom or the like); or a salt thereof. Further, provided is a pharmaceutical composition containing such a thionucleoside derivative or a salt thereof.

Claim (Index 3):
The method according to  claim 1 , wherein the compound of Formula [A1] is reacted with a compound of the formula [S4], and wherein the compound of the formula [S4] is (2S)-benzyl 2-(((RS)-chloro(phenoxy)phosphoryl)amino)propanoate,\n (2S)-benzyl 2-(((RS)-chloro(4-chlorophenoxy)phosphoryl)amino)propanoate, S-(2-(((RS)-chloro(phenoxy)phosphoryl)oxy)ethyl)2,2-dimethylpropanethioate, or (2RS,4R)-2-(4-nitrophenoxy)-4-phenyl-1,3,2-dioxaphosphinane 2-oxide.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 95.0
- Lexical Diversity: 2.06349
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15581834', '11816940', '14852738', '14873966', '13198819']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7398812582074564
- 35 USC 102 Novelty (BERT): 0.614206709064532
- Combined Prediction Score: 0.727313803293164
- Mean Citation Score: 370.45701
- Max Citation Score: 668.1111
- Similarity Product: 455.6075945953846

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test