PATENT CLAIM ANALYSIS

Application Number: 15776532
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "230500"]

Abstract:
Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.

Claim (Index 1):
A compound of Formula I or a pharmaceutically acceptable salt thereof: wherein: each Y is independently C\u2550O, CH\u2014R 6 , or N-L-R 3  R 3  with the proviso that at least one Y must be CH\u2014R 6 ; X is O or CH 2 ; R 1  is C 1-6 alkyl wherein said alkyl may contain cycloalkyl portions; W is a bond, \u2014CH\u2550CH\u2014, \u2014C\u2261C\u2014, C 1-3 alkylene, \u2014CH 2 C(O)NH\u2014, \u2014NHC(O)\u2014, \u2014N(CH 3 )C(O)\u2014, \u2014N(CH 3 )C(O)CH 2 \u2014, \u2014C(O)\u2014, \u2014CH 2 (CO)\u2014, or \u2014NHC(O)CH 2 \u2014, wherein each W is optionally substituted by 1 or 2 methyl groups; R 2  is H, C 1-6 alkyl, C 5-14 aryl, C 3-7 cycloalkyl, C 3-7 cycloalkenyl, C 3-9 heterocycle, or C 5-9 heteroaryl, wherein each R 2  group is optionally substituted by one to four substituents selected from halo, C 1-6 alkyl, C 1-6 hetereoalkyl, or C 1-6 alkylene or C 1-6 hetereoalklylene wherein said C 1-6 alkylene or C 1-6 hetereoalklylene is bonded to adjacent carbon atoms on said C 5-14 aryl, C 3-7 cycloalkyl, C 3-7 cycloalkenyl, C 3-9 heterocycle, or C 5-9 heteroaryl to form a fused ring; each L is independently a bond, \u2014CH 2 (CO)\u2014, \u2014C 1-3 alkylene-, \u2014SO 2 \u2014, \u2014C(O)\u2014, \u2014C(S)\u2014, \u2014C(NH)\u2014, \u2014C(O)NH\u2014, \u2014C(O)NHCH 2 \u2014, \u2014C(O)N\u2014, \u2014C(O)OCH 2 \u2014, \u2014C(O)O\u2014, \u2014C(O)C(O)\u2014, \u2014SO 2 \u2014NH\u2014, or \u2014CH 2 C(O)\u2014; each R 3  is independently H, CN, oxo, C 1-6 alkyl, C 5-14 aryl, CH 2 C 5-14 aryl, CH 2 C 3-7 cycloalkyl, C 3-7 cycloalkyl, C 3-7 spirocycloalkyl, C 3-7 cycloalkenyl, C 3-9 heterocycle, or C 5-9 heteroaryl, or an R 3  may join together with an R 6  or an R 3  to form a fused 5-7 membered ring, and wherein each R 3  group is optionally substituted by one to four substituents selected from halo, oxo, C 1-6 alkyl, C 3-7 cycloalkyl, C 1-3 fluoroalkyl, \u2014OC 1-6 alkyl, \u2014C(O)R 4 , \u2014C(O)NR 4 , \u2014C(O)NHR 4 , C 5-14 aryl, C 1-6 hetereoalkyl, \u2014B(OH) 2 , C 3-9 heterocycle, C 5-9 heteroaryl, \u2014C(O)OC 1-6 alkyl, or two substituents may bond together to form a fused, spiro, or bridged ring and that fused, spiro, or bridged ring may optionally be substituted with R 4 ; R 4  is CN, halo, \u2014OC 1-6 alkyl, C 1-6 alkyl, C 3-7 cycloalkyl, C 3-9 heterocycle, or C 5-14 aryl; each R 5  is independently H, C 1-3 alkyl, C 3-6 cycloalkyl, CH 2 F, CHF 2 , or CF 3 ; each R 6  is independently H, oxo, C 1-3 alkyl, C 5-14 aryl, C 3-9 heterocycle, C 5-9 heteroaryl, \u2014C(O)NR 4 , or \u2014C(O)NHR 4 , or both R 6  may together comprise 2-4 carbon atoms and join together to form a bridged ring system, or R 6  may represent a gem di-C 1-3 alkyl; and wherein each heterocycle, heteroaryl, heteroalkyl, and heteroalkylene comprises one to three heteroatoms selected from S, N, B, or O.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 93.0
- Lexical Diversity: 1.05882
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15314549', '15759363', '15326100', '14413425', '14364409']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.798910183476459
- 35 USC 102 Novelty (BERT): 0.5647492774376638
- Combined Prediction Score: 0.7754940928725795
- Mean Citation Score: 402.426436
- Max Citation Score: 435.95514
- Similarity Product: 355.5162548114025

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test