PATENT CLAIM ANALYSIS

Application Number: 16190243
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["604", "006150"]

Abstract:
A system and method for producing high levels of autologous IL-1RA cytokine, includes a blood collection vessel, a cover, a portion of separation gel, an anticoagulant portion, a plasma collection syringe comprising a sharp needle, a buffy coat collection syringe and an incubation tube with cover. The blood collection vessel is adapted such that when containing whole blood and being centrifuged, after treatment yields separation fractions comprising, a first fraction of RBCs sediment, a second fraction of said gel, a third fraction comprising WBCs, platelets and a fourth fraction of plasma solution.

Claim (Index 11):
A method for producing of autologous IL-1RA cytokine in a closed system, the method comprising steps of:\n a. obtaining a vacuum tube system for producing autologous IL-1RA cytokine comprising:\n i. a blood collection vacuum tube; \n ii. a tube cover; \n iii. a portion of separation gel; \n iv. an anticoagulant portion; \n v. a plasma collection syringe comprising a sharp needle; \n vi. a buffy coat collection syringe; and \n vii. an incubation tube with a cover comprising washed and pretreated borosilicate glass beads in a size of about 0.5-5 mm; \n b. placing said anticoagulant portion and said portion of separation gel in said vacuum tube; said separation gel is adapted as a barrier and as a separating element between separation fractions c. filling said blood collection vacuum tube with blood sample; d. separating by centrifugation there by obtaining separation fractions comprising, a first fraction of RBCs sediment, a second fraction of said gel, a third fraction comprising WBCs, platelets, growth factors and plasma solution fraction; e. discarding a portion of plasma with said plasma collection syringe comprising a sharp needle; f. extracting the remaining plasma and WBCs solution with said plasma collection syringe; g. transferring said solution into said incubation tube; and h. incubating said incubation tube; such that a high concentration of said autologous IL-1RA cytokine is obtained.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 98.0
- Lexical Diversity: 1.75
- Patent Class: 604.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14375950', '14373978', '15515996', '14937241', '13840562']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.763983955379323
- 35 USC 102 Novelty (BERT): 0.643350111846138
- Combined Prediction Score: 0.7519205710260045
- Mean Citation Score: 396.272032
- Max Citation Score: 678.8923
- Similarity Product: 584.7653392850935

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test