PATENT CLAIM ANALYSIS

Application Number: 16030815
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-03
Patent Classification: ["435", "455000"]

Abstract:
The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.

Claim (Index 1):
A method of making a somatic cell more susceptible to reprogramming to a less differentiated state, comprising: introducing an exogenous nucleic acid encoding an Oct 4 protein operably linked to at least one regulatory sequence into the somatic cell, thereby increasing expression of Oct4 protein in the somatic cell, wherein increased expression of Oct4 protein makes the cell more susceptible to reprogramming; and wherein the exogenous nucleic acid is transiently transfected into the somatic cell.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 95.0
- Lexical Diversity: 1.44737
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15588062', '12703061', '14923321', '13646444', '13646430']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6104196946758276
- 35 USC 102 Novelty (BERT): 0.5840048281518505
- Combined Prediction Score: 0.6077782080234299
- Mean Citation Score: 451.102838
- Max Citation Score: 475.77924
- Similarity Product: 456.4160087276889

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test