PATENT CLAIM ANALYSIS

Application Number: 15751782
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["544", "280000"]

Abstract:
Disclosed are a compound related to inhibiting the activity of an IRAK4 kinase, a pharmaceutical composition thereof, a use thereof in preparing drugs, a method in which same is used for inhibiting the activity of the IRAK4 kinase and a method in which same is used for treating and/or preventing IRAK4 kinase mediated diseases or conditions in mammals (especially humans). The compound has a structural formula I.

Claim (Index 2):
The compound according to  claim 1 , wherein:\n A is phenyl or 5- to 10-membered heteroaryl, optionally substituted with one or more R 1  groups; L is O, or NR 2 ; G is C 1-6  alkyl, 3- to 6-membered cycloalkyl, 4- to 6-membered heterocyclyl, or C 6-10  aryl, optionally substituted with one or more R 3  groups; Z is phenyl or 5- to 10-membered heteroaryl, optionally substituted with one or more R 4  groups; each R 1  is independently halogen, hydroxy, alkyl, haloalkyl, heterocyclyl, alkyloxyalkyl, alkyloxy, amino, dialkylamino, carboxy, or alkylsulfonyl; R 2  is hydrogen or alkyl; each R 3  is independently hydroxy, oxo, alkyl, heterocyclyl, heteroaryl, hydroxyalkyl, alkyloxyalkyl, alkyloxy, alkylacylamino, alkylcarbonyl, or alkylaminoacyl; each R 4  is independently alkyl, oxo, cyano, cycloalkyl, heterocyclyl, aryl, heteroaryl, haloalkyl, hydroxyalkyl, heterocyclylcarbonyl, or R 4a R 4b NC(\u2550O)\u2014; and each of R 4a  and R 4b  is independently hydrogen, alkyl, haloalkyl, cycloalkyl, alkyloxyalkyl, heterocyclylalkyl, heteroarylalkyl, or heterocyclyl; wherein said heterocyclyl in R 4 , R 4a  and R 4b , as an independent group or a part of a group, is optionally substituted with one or more substituents independently selected from the group consisting of alkyl and oxo; and wherein said heterocyclyl and said heteroaryl contain one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, or a stereoisomer, tautomer, solvate, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 10.0
- Percentile: 88.0
- Lexical Diversity: 1.6087
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15022248', '15799315', '15314938', '14423078', '15257926']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8410465917728439
- 35 USC 102 Novelty (BERT): 0.541609722980971
- Combined Prediction Score: 0.8111029048936567
- Mean Citation Score: 378.723926
- Max Citation Score: 398.73517
- Similarity Product: 299.1962341234797

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test