PATENT CLAIM ANALYSIS

Application Number: 15767775
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-02
Patent Classification: ["548", "466000"]

Abstract:
The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—R z  and N; R 1  is selected from:     -(Alk 1 ) t -Cyc 1 ; wherein t is 0 or 1; Optionally substituted C 1-6  acyclic hydrocarbon groups       R 2  is selected from hydrogen; halogen; and C 1-3  hydrocarbon groups optionally substituted with one or more fluorine atoms; R 3  is hydrogen or a group L 1 -R 7 ; R 4  is selected from hydrogen; methoxy; and optionally substituted C 1-3  alkyl; and R 4a  is selected from hydrogen and a C 1-3  alkyl group; wherein R z , Alk 1 , Cyc 1 , L 1  and R 7  are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof. The compounds are inhibitors of ERK1/2 kinases and will be useful in the treatment of ERK1/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the treatment of cancer.

Claim (Index 16):
A combination of a compound according to  claim 1 , or a pharmaceutically acceptable salt thereof, and another therapeutic agent.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 2.32075
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14358678', '15764960', '14529902', '12298462', '15118072']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.767941979686075
- 35 USC 102 Novelty (BERT): 0.5499608096709532
- Combined Prediction Score: 0.7461438626845628
- Mean Citation Score: 389.51534
- Max Citation Score: 417.22003
- Similarity Product: 266.74671536158803

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test