PATENT CLAIM ANALYSIS

Application Number: 16117824
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["422", "502000"]

Abstract:
Disclosed herein is a multi-functional microfluidics device capable of isolation of nucleic acids, purification of nucleic acids, performance of Polymerase Chain Reactions (PCRs), in situ hybridization of nucleic acids, fluorescent signal detections and the like. The apparatus comprises an integration of a plurality of reagent chambers, a sample input, a reaction chamber, a detection chamber, and a waste chamber; wherein the plurality of reagent chambers is fluidly connected to the reaction chamber, and is configured to store a plurality of reagents; wherein the sample input is fluidly connected to the reaction chamber, and is configured to receive a sample; wherein the waste chamber is fluidly connect to the reaction chamber and is configured to receive a reaction waste from the reaction chamber.

Claim (Index 21):
A method of using an apparatus of  claim 1  for extracting nucleic acids, comprising:\n adding a sample to the reaction chamber; \n adding a lysis buffer from one of the plurality of reagent chambers to the reaction chamber; \n adding a solution of magnetic beads to the reaction chamber and extracting nucleic acids by association of nucleic acids with the magnetic beads; \n applying a magnetic field to the reaction chamber to secure the nucleic acids on magnetic beads to a bottom of the reaction chamber; \n adding a wash buffer to the reaction chamber and washing cellular lysate to the waste chamber; \n adding an elution buffer to release nucleic acids from the magnetic bead; \n applying a magnetic field to the reaction chamber to secure the magnetic beads to the bottom of the reaction chamber; \n obtaining the nucleic acids.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 96.0
- Lexical Diversity: 2.48214
- Patent Class: 422.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13343834', '11262523', '13397416', '15906899', '13759557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8069479420298058
- 35 USC 102 Novelty (BERT): 0.4853966003410385
- Combined Prediction Score: 0.7747928078609291
- Mean Citation Score: 230.644414
- Max Citation Score: 235.55568
- Similarity Product: 161.42026846035003

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test