PATENT CLAIM ANALYSIS

Application Number: 16021551
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "210210"]

Abstract:
A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR 1  or NR 2 R 3 , and R 1  ,R 2 , R 3  and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.

Claim (Index 12):
A process for preparing a compound of formula (Ib) comprising:\n [A] reacting substituted hydrazine (Va) with an acid (VI) in presence of a coupling agent selected from the group consisting of EDCI or HOBT-DCC and PyBop to provide an intermediate of formula (VIIa), [B] removing the benzyl protecting group of the intermediate (VIIa) with a source of hydrogen in presence of Pd catalyst to provide the debenzylated product (VIIIa), and [C] contacting compound (VIIIa) with a sulfating agent in the presence of solvent to obtain compound of formula (Ib) wherein:\n M is hydrogen; \n R 2  is hydrogen or optionally substituted C 1-6  lower alkyl; \n R 3  is a radical selected from any of following groups consisting of: \n (1) C 1-6  straight or branched chain alkyl which is optionally substituted; \n (2) C 3-7  cycloalkyl which is optionally substituted; \n (3) C 4-7  saturated heterocycles containing at least one heteroatom selected from O, N and S wherein the said heterocycle is optionally substituted, the ring S is optionally oxidized to S(O) or S(O) 2  and the free ring N atom may optionally take a substituent; \n (4) C 1-6  straight or branched chain alkylcarbonyl which is optionally substituted; \n (5) C 3-7  cycloalkylcarbonyl which is optionally substituted; \n (6) C 4-7  membered saturated heterocyclylcarbonyl containing at least one heteroatom selected from O, N and S wherein the said heterocycle is optionally substituted, the ring S is optionally oxidized to S(O) or S(O) 2  and the free ring N atom may optionally take a substituent; \n (7) C 3-7  membered saturated heterocyclyl (C 1-6 ) alkylcarbonyl wherein the said heterocycle has the same definition as defined in (6), and the free ring N atom may optionally take a substituent; \n (8) C 6-10  arylcarbonyl which is optionally substituted; \n (9) C 6-10  aryl (C 1-6 ) alkylcarbonyl which is optionally substituted; \n (10) C 5-6  membered heteroarylcarbonyl containing at least one heteroatom selected from O, S and N wherein the heteroaryl is optionally substituted; \n (11) C 5-6  heteroaryl (C 1-6 ) alkylcarbonyl wherein the said heteroaryl has the same definition as defined in (10); \n (12) CF 3 CO\u2014, CH 3 SO 2 \u2014, NH 2 CO\u2014, and NH 2 SO 2 SO 2 \u2014; \n (13) C 6-10  aryl which is optionally substituted; \n (14) C 5-6  membered heteroaryl which is optionally substituted; \n (15) or R 2  and R 3  together may form an optionally substituted ring system and the said ring may contain another heteroatom selected from O, N, and S.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 94.0
- Lexical Diversity: 1.41304
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15171237', '13690398', '13917932', '14300493', '12812763']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8334465595402785
- 35 USC 102 Novelty (BERT): 0.576389090214792
- Combined Prediction Score: 0.8077408126077298
- Mean Citation Score: 499.65012800000005
- Max Citation Score: 568.8289
- Similarity Product: 364.9681902895272

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test