PATENT CLAIM ANALYSIS

Application Number: 15925463
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-01
Patent Classification: ["436", "518000"]

Abstract:
Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.

Claim (Index 25):
The system of  claim 24 , wherein the optical sensor comprises an input waveguide and an output waveguide having optical coupling region therebetween configured to increase coupling of a wavelength component from said input waveguide to said output waveguide when said capture probe binds to the nucleic acid molecule of interest forming said duplex and said antibody binds to said duplex.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 2.1746
- Patent Class: 436.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14209746', '14234134', '15436585', '13979099', '11809867']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6906763816281379
- 35 USC 102 Novelty (BERT): 0.5043112359659573
- Combined Prediction Score: 0.6720398670619199
- Mean Citation Score: 266.197624
- Max Citation Score: 309.56076
- Similarity Product: 234.50430370680573

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test