PATENT CLAIM ANALYSIS

Application Number: 16066328
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["546", "210000"]

Abstract:
Disclosed is a process for the synthesis of efinaconazole (I), starting from 1-[[(2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole and 4-methylenepiperidine, as free base or hydrochloride, in an organic solvent, under anhydrous conditions and in the presence of neutralising agents and reaction-promoting metal species. (1) The process is particularly advantageous because it gives rise to efinaconazole in high yields and purity, and uses little more than the stoichiometric amount of 4-methylenepiperidine, a rather expensive commercially available reagent.

Claim (Index 4):
The process according to  claim 1  wherein the neutralising agents are selected from organic amines and proton acceptors.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 94.0
- Lexical Diversity: 1.42647
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15577818', '13818897', '15573082', '15194773', '14890354']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7151980513132479
- 35 USC 102 Novelty (BERT): 0.4932270423195205
- Combined Prediction Score: 0.6930009504138752
- Mean Citation Score: 130.15980280000002
- Max Citation Score: 138.50858
- Similarity Product: 86.0275316100347

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test