PATENT CLAIM ANALYSIS

Application Number: 15860200
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["424", "139100"]

Abstract:
The present invention provides isolated human or humanized antibodies or antigen-binding fragments thereof which specifically bind to Growth and Differentiation Factor-8 (GDF8) and block GDF8 activity. The antibodies and antibody fragments of the present invention may be used in therapeutic methods for treating conditions or disorders which are ameliorated or improved by inhibition of GDF8.

Claim (Index 31):
An antibody or antigen-binding fragment thereof, which specifically binds to wild-type mature human growth and differentiation factor-8 (GDF8), wherein the antibody or antigen-binding fragment comprises a heavy chain and a light chain, each comprising CDR1, CDR2 and CDR3 domains, and wherein the heavy chain comprises: an amino acid sequence which differs from SEQ ID NO: 360 by only a single amino acid substitution; and the light chain comprises: an amino acid sequence which differs from SEQ ID NO: 368 by only a single amino acid substitution, wherein the antibody or antigen-binding fragment has at least the same binding affinity and specificity for (GDF8) as an antibody or antigen-binding fragment thereof which comprises SEQ ID NO: 360 and SEQ ID NO: 368.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 1.34091
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14974147', '13115170', '14462085', '15637867', '14447444']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7879246932185808
- 35 USC 102 Novelty (BERT): 0.6895384823116487
- Combined Prediction Score: 0.7780860721278877
- Mean Citation Score: 629.0445040000002
- Max Citation Score: 750.4044
- Similarity Product: 680.4404785853147

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test