PATENT CLAIM ANALYSIS

Application Number: 15868201
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["506", "009000"]

Abstract:
The present invention relates to the identification of chemokine biomarkers predictive of future acute coronary syndromes including unstable angina pectoris (UAP). The present invention also identifies particular chemokines as potential therapeutic targets for intervention in cardiovascular diseases.

Claim (Index 12):
A method for identifying a subject at increased risk of a future acute cardiovascular syndrome or event, the method comprising:\n a) determining an amount of at least one compound selected from the group consisting of CCL3 (chemokine (C-C motif) ligand 3) or CCL5 (chemokine (C-C motif) ligand 5) and determining an amount of CCL18 (chemokine (C-C motif) ligand 18) in a sample obtained from the subject by measuring the level of expression of CC18 mRNA, and CCL3 mRNA or CCL5 mRNA; b) identifying a subject as having an increased risk of a future acute cardiovascular syndrome or event if the sample from the subject was determined to have elevated CCL18 mRNA, in combination with elevated CCL5 mRNA, or elevated CCL18 mRNA relative to a healthy control.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 1.13889
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12677437', '14388164', '15128560', '15171713', '13575354']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6138528147939558
- 35 USC 102 Novelty (BERT): 0.6471850413530985
- Combined Prediction Score: 0.6171860374498701
- Mean Citation Score: 379.722638
- Max Citation Score: 647.8530000000002
- Similarity Product: 578.1931525933744

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test