PATENT CLAIM ANALYSIS

Application Number: 15906404
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["702", "019000"]

Abstract:
The invention provides methods for identifying rare variants near a structural variation in a genetic sequence, for example, in a nucleic acid sample taken from a subject. The invention additionally includes methods for aligning reads (e.g., nucleic acid reads) to a reference sequence construct accounting for the structural variation, methods for building a reference sequence construct accounting for the structural variation or the structural variation and the rare variant, and systems that use the alignment methods to identify rare variants. The method is scalable, and can be used to align millions of reads to a construct thousands of bases long, or longer.

Claim (Index 33):
The method of  claim 21 , further comprising identifying a variation present in the one or more sequence reads that is not present in the reference graph, and adding that variation to the reference graph.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 88.0
- Lexical Diversity: 1.96552
- Patent Class: 702.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15196345', '14041850', '14811057', '14517406', '14016833']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2293714387424836
- 35 USC 102 Novelty (BERT): 0.6327979825687275
- Combined Prediction Score: 0.269714093125108
- Mean Citation Score: 436.52065000000016
- Max Citation Score: 459.58737
- Similarity Product: 273.03000797312023

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test