PATENT CLAIM ANALYSIS

Application Number: 16253026
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["424", "423000"]

Abstract:
Disclosed are various bioactive and/or biocompatible materials and methods of making the same.

Claim (Index 12):
A method of making an implant material, the method comprising:\n (a) selectively lysing allograft cancellous bone obtained from a donor, wherein the cancellous allograft bone comprises bone marrow, wherein selective lysing comprises exposing allograft cancellous bone obtained from a donor to a lysing fluid to selectively lyse non-mesenchymal stem cells while not lysing mesenchymal stem cells contained in the allograft cancellous bone, wherein the lysing fluid is water or less than 1M acetic acid, wherein the intracellular growth factors contained in the lysed non-mesenchymal stem cells are released into the lysing fluid, and wherein the lysing fluid after lysing comprises mesenchymal stem cells and intracellular growth factors released from non-mesenchymal stem cells; and (b) mixing the lysing fluid obtained from step (a) that comprises mesenchymal stem cells an released intracellular growth factors with allograft cortical bone, wherein at least one of the mesenchymal stem cells attach or otherwise associate with the allograft cortical bone, and wherein at least one of the released intracellular growth factors bind or otherwise associate with the allograft cortical bone.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 99.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15654830', '15525418', '15016072', '14880675', '13458286']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7076608913916617
- 35 USC 102 Novelty (BERT): 0.5284440859613369
- Combined Prediction Score: 0.6897392108486292
- Mean Citation Score: 245.96051799999995
- Max Citation Score: 355.55643
- Similarity Product: 283.89888224665583

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test