PATENT CLAIM ANALYSIS

Application Number: 16129867
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "471000"]

Abstract:
The invention relates to 1-(3-sulfonylphenyl)-3-(cyclopent-2-en-1-yl)urea derivatives, and their use in treating or preventing diseases and conditions mediated by the CXCR2 receptor. In addition, the invention relates to compositions containing the derivatives and processes for their preparation.

Claim (Index 5):
The method according to  claim 1 , wherein R 4  is selected from the group consisting of:\n a) C 1-6 alkyl optionally substituted by one or more substituents independently selected from the group consisting of: fluoro, C 1-3 alkoxy, C 1-3 fluoroalkyl, C 1-3 fluoroalkoxy and hydroxy; d) \u2014(CH 2 ) q -heterocyclyl; wherein\n q is 0, 1 or 2; \n the \u2014(CH 2 ) q \u2014 linker is optionally substituted by one or more groups independently selected from fluoro and methyl optionally substituted by one or more deuterium; \n the heterocyclyl group is 3, 4, 5 or 6-membered and is attached to the \u2014(CH 2 ) q -via a ring carbon atom; \n the heterocyclyl may be saturated or unsaturated; and \n wherein the heterocyclyl group is optionally substituted by one or more substituents independently selected from the group consisting of deuterium, C 1-3 alkyl optionally substituted by one or more deuterium, fluoro, C 1-3 fluoroalkyl, hydroxy, C 1-3 alkoxy, C 1-3 alkoxyC 1-3 alkyl, C 1-3 fluoroalkoxy, C 3-6 cycloalkyl and \u2014(CH 2 ) s NR 4c R 4d ; or two substituents on the heterocyclyl group together with the interconnecting atom(s), form a further 5 or 6-membered ring which further ring may be saturated, unsaturated or aromatic when the further ring is ortho-fused; and which further ring optionally contains one additional heteroatom selected from nitrogen and oxygen; and which further ring is optionally independently substituted by one or more fluoro or methyl substituents; wherein s is 0 or 1, and wherein R 4c  and R 4d  are independently C 1-3 alkyl, or R 4c  and R 4d , together with the nitrogen to which they are attached, form a 4, 5 or 6-membered saturated ring which ring is optionally substituted by one or more fluoro substituent; and \n e) \u2014(CH 2 ) r \u2014C 3-6 cycloalkyl; wherein\n r is 0, 1 or 2; \n the \u2014(CH 2 ) r \u2014 linker is optionally substituted by one or more groups independently selected from fluoro and methyl optionally substituted by one or more deuterium; and \n wherein the C 3-6 cycloalkyl group is optionally substituted by one or more substituents independently selected from the group consisting of C 1-3 alkyl optionally substituted by one or more deuterium, fluoro, C 1-3 fluoroalkyl, hydroxy, C 1-3 alkoxy, C 1-3 alkoxyC 1-3 alkyl, C 1-3 fluoroalkoxy and \u2014(CH 2 ) t NR 4e R 4f ; or wherein two substituents on the cycloalkyl group together with the interconnecting atom(s) form a further 5 or 6-membered ring which further ring is saturated, unsaturated or aromatic when the further ring is ortho-fused; and which further ring optionally contains one heteroatom selected from nitrogen and oxygen; and which further ring is optionally independently substituted by one or more fluoro or methyl substituents; wherein t is 0 or 1, and wherein R 4e  and R 4f  are independently C 1-3 alkyl, or R 4e  and R 4f , together with the nitrogen to which they are attached, form a 4, 5 or 6-membered saturated ring which ring is optionally substituted by one or more fluoro substituent.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 97.0
- Lexical Diversity: 1.37143
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15314124', '15175363', '15502356', '15799771', '14354500']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7955548530721424
- 35 USC 102 Novelty (BERT): 0.6141472762988789
- Combined Prediction Score: 0.777414095394816
- Mean Citation Score: 405.007728
- Max Citation Score: 570.4564
- Similarity Product: 482.8302295769692

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test