PATENT CLAIM ANALYSIS

Application Number: 15746966
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-11
Patent Classification: ["544", "331000"]

Abstract:
Provided is an EGFR inhibitor and a pharmaceutically acceptable salt and a polymorph thereof, and a use thereof. In particular, provided is a polymorph, a pharmaceutically acceptable salt or a prodrug of N-(2-(4-(dimethylamino)piperid-1-yl)-5-(5-fluoro-4-(1-methyl-1H-pyrazol-4-yl) pyrimidin-2-ylamino)-4-methoxy phenyl) acrylamide. In addition, also provided is a pharmaceutical composition containing the inhibitor and a use thereof.

Claim (Index 6):
The compound of  claim 3 , or a pharmaceutically acceptable salt, or a prodrug thereof, wherein the crystal is selected from the group consisting of:\n crystal form I of the compound of formula X, which has an X-ray powder diffraction pattern with diffraction angle 2\u03b8(\u00b0) values of the group I-1: 8.74\u00b10.10, 9.80\u00b10.10, 15.63\u00b10.10, and 21.38\u00b10.10 (the highest peak); crystal form II of the compound of formula X, which has an X-ray powder diffraction pattern with diffraction angle 2\u03b8(\u00b0) values of the group II-1: 9.47\u00b10.10 (the highest peak), 17.34\u00b10.10, 18.87\u00b10.10, and 23.89\u00b10.10; crystal form III of the compound of formula X, which has an X-ray powder diffraction pattern with diffraction angle 2\u03b8(\u00b0) values of the group III-1: 9.72\u00b10.10, 18.41\u00b10.10, 23.89\u00b10.10 (the highest peak) and 28.02\u00b10.10; crystal form IV of the compound of formula X, which has an X-ray powder diffraction pattern with diffraction angle 2\u03b8(\u00b0) values of the group IV-1: 7.69\u00b10.10 (the highest peak), 18.90\u00b10.10; and crystal form V of the compound of formula X, which has an X-ray powder diffraction pattern with diffraction angle 2\u03b8(\u00b0) values of the group V-1: 8.28\u00b10.10, 8.89\u00b10.10 (the highest peak), 9.44\u00b10.10, 17.76\u00b10.10.

Metadata:
- Claim Count in Document: 10.0
- Percentile: 86.0
- Lexical Diversity: 1.85366
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16098103', '13019262', '15753993', '14631712', '15571582']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7823540986393823
- 35 USC 102 Novelty (BERT): 0.5511902599722085
- Combined Prediction Score: 0.759237714772665
- Mean Citation Score: 313.714576
- Max Citation Score: 425.19266
- Similarity Product: 301.58501492837433

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test