PATENT CLAIM ANALYSIS

Application Number: 15781493
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["554", "069000"]

Abstract:
Disclosed is a method capable of selectively synthesizing cationic lipids by controlling the introduction rate of a fatty acid group with respect to an oligoalkyleneamine by the change of reaction conditions.

Claim (Index 1):
A method for preparing a cationic lipid represented by Formula 1, comprising reacting an oligoalkyleneamine represented by Formula 2, with a fatty acid alkyl ester represented by Formula 3 to prepare the cationic lipid of Formula 1: in the formulae 1 to 3, n and m are independently 0 to 12, with the proviso that 1\u2264n+m\u226412, a and b are independently 1 to 6, R1, R2, R3 and. R4 are each independently hydrogen, or saturated or unsaturated. fatty acid group having 12 to 26 carbon atoms, with the proviso that at least one of R1 and R4 is saturated or unsaturated fatty acid group having 12 to 26 carbon atoms, R is saturated or unsaturated hydrocarbon having 11 to 25 carbon atoms, and R5 is an alkyl group having from 1 to 14 carbon atoms.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 94.0
- Lexical Diversity: 1.18519
- Patent Class: 554.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15251764', '15186217', '14496118', '14888802', '14310708']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6119574452007253
- 35 USC 102 Novelty (BERT): 0.4963575400686744
- Combined Prediction Score: 0.6003974546875203
- Mean Citation Score: 217.84313000000003
- Max Citation Score: 223.73969
- Similarity Product: 162.98775146669985

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test