PATENT CLAIM ANALYSIS

Application Number: 15906712
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["514", "230200"]

Abstract:
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R 1 -R 4  are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X 3  or P2X 2/3  receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.

Claim (Index 9):
A compound according to  claim 1 , wherein R 5  and R 6  are joined to form:\n an optionally substituted heteroaryl or an optionally substituted 5 or 6-membered heterocyclic ring; an optionally substituted pyrrolidine, piperazine or piperidine; an optionally substituted imidazole, pyrazole, tetrazole, or triazole; pyrrolidine optionally substituted with one or more C 1  to C 6  alkyl or C 1  to C 6  alkoxy; imidazole substituted with one or more C 1  to C 6  alkyl; a pyrazole substituted with one or more C 1  to C 6  alkyl; tetrazole substituted with one or more C 3  to C 6  cycloalkyl, C 1  to C 6  alkyl, C 1  to C 6  hydroxyalkyl, C 1  to C 6  alkyl containing 1-3 fluorine atoms, and C 3  to C 6  cycloalkyl-C 1  to C 6  alkyl; triazole substituted with one or more C 3  to C 6  cycloalkyl, C 1  to C 6  alkyl containing 1-3 fluorine atoms, and C 1  to C 6  alkyl; a piperidine substituted with one or more C 1  to C 6  alkoxy, halogen, C 1  to C 6  alkyl containing 1-3 fluorine atoms, C 1  to C 6  alkyl, or CONH 2 ; a piperazine substituted with one CONH 2 ; or 3-methoxy-pyrrolidine, 3-methyl-3-methoxy-pyrrolidine, 2,5-dimethjyl-imidazole, 5-ethyl-pyrazole, 5-propyl-tetrazole, 5-cyclopropyl-tetrazole, 5-propyl-tetrazole, 5-isopropyl-tetrazole, 5-ethyl-tetrazole, 5-cyclobutyl-tetrazole, 5-cyclopropylmethyl-tetrazole, 5-methyl-tetrazole, 5-hydroxymethyl-tetrazole, 5-difluoromethyl-tetrazole, 5-(2,2,2-trifluoroethyl)-tetrazole, 5-(1,1-difluoroethyl)-tetrazole, 5-cyclopropyl-triazole, 5-difluoromethyl-triazole, 5-trifluoromethyl-triazole, 5-methyl-triazole, 5-isopropyl-triazole, 5-propyl-triazole, 5-ethyl-triazole, 5-tert-butyl-triazole, 5-cyclobutyl-triazole, 5-(1,1-difluoroethyl)-triazole, 5-(2,2,2-trifluoroethyl)-triazole, 3,5-dimethyl-1,2,4-triazole, 4-methyl-piperidine, 4,4-dimethyl-piperidine, 4,4-difluoro-piperidine, 4-methyl-4-carboxamido-piperidine, 4-fluoro-piperidine, 4-trifluoromethyl-piperidine, 4-fluoromethyl-piperidine, 4-methyl-4-methoxy-piperidine, 4-methoxy-piperidine, or 3-methoxy-piperidine, or 4-carboxamido-piperazine.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.69811
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15105526', '15184800', '15876810', '12337683', '12142846']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8358682246149363
- 35 USC 102 Novelty (BERT): 0.6231771745518545
- Combined Prediction Score: 0.8145991196086281
- Mean Citation Score: 481.92710199999993
- Max Citation Score: 577.50775
- Similarity Product: 534.5678461007178

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test