PATENT CLAIM ANALYSIS

Application Number: 16102652
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-12
Patent Classification: ["435", "288700"]

Abstract:
Provided are systems and methods for obtaining a three-dimensional micro-tissue. For example, the system may include at least one cell culture device that may include one or more wells. Each well may include an opening at an upper surface of the cell culture device. Each well may include a bottom located towards a lower surface of the cell culture device. The bottom may be characterized by a bottom surface area inside each well. Each well may include a wall extending from the opening to the bottom surface area to define a total volume. Each well may be characterized by an aggregation factor greater than 800.

Claim (Index 11):
A method for characterizing a three-dimensional micro-tissue, comprising:\n providing a system for obtaining a three-dimensional micro-tissue, comprising:\n a cell culture device, comprising:\n a plurality of wells, each well comprising:\n an opening at an upper surface of the device, the opening characterized by an opening cross-sectional area; \n a bottom located towards a lower surface of the device, the bottom characterized by a bottom surface area inside the well, the bottom surface area comprising a planar portion, and the bottom characterized by transparency effective to permit imaging or spectroscopy inside each well from below the lower surface of the cell culture device; and \n a wall extending from the opening to the bottom, the wall defining: \n \u2003a total volume between the opening and the bottom; \n \u2003a neck located below the opening, the neck characterized by \n \u2003a neck cross-sectional area parallel to the opening; \n \u2003a concentrating volume between the neck and the opening; and \n \u2003a culturing volume between the neck and the bottom, \n \n each well characterized by an aggregation factor of greater than 800, the aggregation factor corresponding to the total volume divided by the bottom surface area divided by a unit length; \n \n providing each well with a suspension of cells, cell clusters, and/or tissue fragments; \n aggregating the cells, cell clusters, and/or tissue fragments from the suspension to the bottom surface area according to the aggregation factor, the aggregating being effective to obtain the three-dimensional micro-tissue; and characterizing the three-dimensional micro-tissue inside each well from below the lower surface of the cell culture device.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 96.0
- Lexical Diversity: 1.94828
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14901635', '13293714', '11952848', '10320717', '10146831']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5487804169139459
- 35 USC 102 Novelty (BERT): 0.4707210768394569
- Combined Prediction Score: 0.540974482906497
- Mean Citation Score: 136.30946799999998
- Max Citation Score: 139.70737
- Similarity Product: 99.7816544774902

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test