PATENT CLAIM ANALYSIS

Application Number: 15948682
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "089000"]

Abstract:
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

Claim (Index 59):
A method of treating a subject suffering from Cryptococcosis, comprising administering to said subject in need thereof, an effective amount of a compound of formula (I) or salt thereof, wherein: R 1  is halo; R 2  is halo; each R 3  is independently cyano, haloalkyl, alkoxy, halo, haloalkoxy, hydroxy, amino, \u2014NR 6 R 9 , \u2014SR 10 , \u2014C(O)R 10 , optionally substituted haloalkyl, optionally substituted arylalkoxy, \u2014C(O)NR 6 R 7 , \u2014CH(OH)-haloalkyl, optionally substituted alkyl, hydroxyalkyl, alkoxyalkyl, isocyano, cycloalkylaminocarbonyl, optionally substituted aryloxyalkyl, optionally substituted arylalkylthio, haloalkylthio, optionally substituted arylalkylsulfonyl, optionally substituted arylalkylsulfinyl, optionally substituted heteroarylalkoxy, optionally substituted arylthioalkyl, or haloalkylcarbonyl; n is 0, 1, 2 or 3; R 4  is aryl optionally substituted with 0, 1, 2 or 3 independent R 8 ; R 5  is H, alkyl, phosphato, phosphito, alkoxyphosphato, or \u2014C(O)alkyl optionally substituted with 1 or 2 amino; R 6  is independently H or alkyl; R 7  is independently H, optionally substituted alkyl, optionally substituted haloalkyl, or optionally substituted arylalkyl; each R 8  is independently cyano, haloalkyl, alkoxy, halo, or haloalkoxy; each R 9  is independently H, alkyl, \u2014C(O)alkyl, \u2014C(O)H, \u2014C(O)haloalkyl, optionally substituted arylalkyl, or optionally substituted haloalkyl; each R 10  is independently H, optionally substituted alkyl, optionally substituted aryl, optionally substituted heterocycloalkyl, or optionally substituted arylalkyl; Ar 2  is R 11  is optionally substituted phenyl, optionally substituted alkyl, optionally substituted thienyl, pyrrolyl, furanyl, optionally substituted pyridyl, \u2014CH(OH)-alkyl, \u2014CH(OH)-haloalkyl, optionally substituted arylalkyl, optionally substituted aryloxyalkyl, haloalkyl, haloalkoxyalkyl, optionally substituted indolyl, optionally substituted benzofuranyl, heterocycloalkyl, or R 12  is R 4 , \u2014C(O)R 4 , \u2014C(O)R 7 , \u2014SO 2 R 4 ; MBG is optionally substituted tetrazolyl, optionally substituted triazolyl, optionally substituted oxazolyl, optionally substituted pyrimidinyl, optionally substituted thiazolyl, or optionally substituted pyrazolyl.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 91.0
- Lexical Diversity: 1.04167
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15088786', '14364276', '14897331', '13527413', '13527426']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8444243674096781
- 35 USC 102 Novelty (BERT): 0.6518458356625232
- Combined Prediction Score: 0.8251665142349627
- Mean Citation Score: 588.618958
- Max Citation Score: 649.0342400000002
- Similarity Product: 596.129481348572

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test