PATENT CLAIM ANALYSIS

Application Number: 16161409
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["544", "182000"]

Abstract:
According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the inhibition of the A 1 -A 2b  or, particularly, the A 2a  receptor wherein the compound of formula A1 has the structure, wherein, A represents Cy 1  or Het A ; Cy 1  represents a 5- to 14-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one, two or three rings, which Cy 1  group is optionally substituted by one or more R 4a  substituents; Het A  represents a 5- to 14-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one, two or three rings and which HetA group is optionally substituted by one or more R4b substituents; B represents a Cy 2  or Het B ; Cy 2  represents a 3- to 10-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one or two rings, which Cy 2  group is optionally substituted by one or more R 4c  substituents; Het B  represents a 3- to 10-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one or two rings and which Het B  group is optionally substituted by one or more R 4d  substituents.

Claim (Index 36):
The method as claimed in  claim 18 , wherein:\n (1) R 8  represents, independently at each occurrence,\n H, \n Cy 3 , Het a , aryl a , C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 3-6  cycloalkyl, which latter seven groups are optionally substituted by one or more substituents selected from halo, \u2014CN, C 3-6  cycloalkyl, aryl, Het 4 , \u2014C(O)OR 10 , \u2014C(O)R 11  and \n \u2014C(O)N(R N1 )(R N2 ), S(O) r R 9aa , S(O) 2 N(R 9ba )(R 9ca ), N(R 9da )S(O) 2 R 9ea  and N(R 9fa )(R 9ga ); \n (2) each aryl a  independently represents a C 6-10  carbocyclic aromatic group, which group may comprise one or two rings; (3) each aryl independently represents a C 6-10  carbocyclic aromatic group, which group may comprise one or two rings and may be substituted by one or more substituents selected from\n halo, \n C 1-6  alkyl, which latter group is optionally substituted by one or more substituents selected from halo, \u2014N(R N4 )(R N5 ) and \u2014OR a , and \n \u2014OR a ; \n (4) R a  represents, independently at each occurrence,\n H, \n C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 3-6  cycloalkyl, C 4-6  cycloalkenyl (which latter five groups are optionally substituted by one or more substituents selected from halo, nitro, CN, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 3-8  cycloalkyl (which latter four groups are optionally substituted by one or more substituents selected from OH, \u2550O, halo, C 1-4  alkyl and C 1-4  alkoxy), OR 12a , S(O) q R 12b , S(O) 2 N(R 12c )(R 12d ), N(R 12e )S(O) 2 R 12f , N(R 12g )(R 12h ), B 9 \u2014C(G 2 )-B 10 \u2014R 12i , aryl 1  and Het b , and which C 3-6  cycloalkyl or C 4-6  cycloalkenyl groups may additionally be substituted by \u2550O), \n S(O) r R 13a , \n S(O) 2 N(R 13b )(R 13c ) or \n C(O)\u2014B 11 \u2014R 13d ; \n (5) R 5a  to R 5j , R 6a  to R 6i , R 7a  to R 7i , R 9a  to R 9i , R 9aa  to R 9ga , R 12a  to R 12i  and R 13a  to R 13d  independently represent, at each occurrence,\n H, \n C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl (which latter three groups are optionally substituted by one or more substituents selected from halo, OH and C 1-4  alkoxy), \n C 3-6  cycloalkyl or C 4-6  cycloalkenyl (which latter two groups are optionally substituted by one or more substituents selected from halo, OH, \u2550O, C 1-6  alkyl and C 1-6  alkoxy), \n Het d ; and/or \n (6) G 2  represents, independently at each occurrence, O.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 97.0
- Lexical Diversity: 3.32099
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14322505', '13576798', '15344048', '15488155', '14112484']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8324562975683713
- 35 USC 102 Novelty (BERT): 0.6478715235869466
- Combined Prediction Score: 0.8139978201702288
- Mean Citation Score: 498.28573399999993
- Max Citation Score: 634.10547
- Similarity Product: 588.1577367933206

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test