PATENT CLAIM ANALYSIS

Application Number: 16212287
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["435", "189000"]

Abstract:
The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.

Claim (Index 3):
The method of  claim 2 , comprising converting a compound selected from the group consisting of:\n a) compounds of formula IVa in which R 1  i) is defined as:\n (1) when \u201ca\u201d is a double bond:\n R 1  is selected from \n oxo (\u2550O), or \n CH\u2014(CH 2 ) n \u2014Z, \n \u2003in which n is 0, 1 or 2 and \n \u2003Z is OH, CHO, C(O)C 1 -C 4 -alkyl; COOH, C(CH 2 )\u2014CH\u2550CH 2 ; \n \u2003C(OH)(CH 3 )\u2014CH\u2550CH 2 ; C(CH 3 )\u2550CH\u2014CH\u2550CH 2 ; or a radical of the formula C(CH 3 )\u2032CH\u2014CH 2 Y \n \u2003in which \n \u2003Y is OH, CH 2 OH, COOH, or CH 2 C(O)CH 3 ; or \n \n (2) when \u201ca\u201d is a single bond:\n R 1  is selected from \n CH 3 ; CHO; CH 2 CH 2 OH; CH\u2550CH 2 ; CH 2 C(O)OH; CH 2 CHO or C 3 H 6 CH(CH 3 )CHO; \n \n and, when \u201ca\u201d is a double bond, it has E or Z configuration; or ii) is a radical of the formula\n CH\u2014(CH 2 ) n \u2014Z \n in which \n n=0 and Z\u2550CHO or COOH; \n n=1 and Z\u2550OH; or \n n=2 and Z\u2550C(O)CH 3 ; COOH, C(CH 2 )\u2014CH\u2550CH 2 ; C(CH 3 )\u2550CH\u2014CH\u2550CH 2 ; \n iii) is a radical of the formula C(CH 3 )\u2550CH\u2014CH 2 Y\n in which Y is OH, CH 2 OH, COOH, or CH 2 C(O)CH 3 ; \n and \u201ca\u201d optionally has E or Z configuration; b) compounds of formula IVb in which R 1  is defined as above or is CH 2 CHO; and c) compounds of formula IVc in which R 1  is defined as above, or is CH\u2014CHO; and one of the radicals R 7  and R 8  is H and the other is C 1 -C 4 -alkyl, or wherein R 7  is ethyl and the double bonds \u201ca\u201d and \u201cd\u201d have Z configuration.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 98.0
- Lexical Diversity: 1.40476
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13297798', '15234529', '14560263', '13798365', '15514706']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5821333470068182
- 35 USC 102 Novelty (BERT): 0.6100901641745342
- Combined Prediction Score: 0.5849290287235898
- Mean Citation Score: 361.44513
- Max Citation Score: 522.1857
- Similarity Product: 517.9640088698029

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test