PATENT CLAIM ANALYSIS

Application Number: 16164282
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["514", "279000"]

Abstract:
Formulation comprising buprenorphine or a pharmaceutically acceptable salt thereof as the sole active ingredient, a viscosity enhancer, and a buffering agent in an amount to provide a pH of from 5.0 to 7.0 are useful for treating opioid withdrawal syndrome.

Claim (Index 12):
A process for preparing a formulation according to  claim 1 , comprising:\n (i) dissolving a suitable amount of buprenorphine or a pharmaceutically acceptable salt thereof in water in a glass container to obtain a buprenorphine concentrated clear solution; (ii) optionally, sterilizing the obtained solution in step (i) by filtration; (iii) in parallel, dissolving an appropriate amount of a buffering agent in water in a volumetric glass container to obtain a clear buffering agent solution; (iv) optionally, sterilizing the obtained solution in step (iii) by heating; (v) adding an appropriate volume of buprenorphine concentrated solution to said buffering agent solution to obtain a final desired concentration of buprenorphine while mixing under continuous stirring; and (vi) slowly adding a proper amount of a thickening agent to the solution of step (v) under continuous stirring until the thickening agent is completely dissolved and a clear and homogenous solution is obtained.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 1.13158
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14416421', '14923630', '10566121', '14490470', '14469063']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6728683572943498
- 35 USC 102 Novelty (BERT): 0.5036185448458598
- Combined Prediction Score: 0.6559433760495008
- Mean Citation Score: 197.053192
- Max Citation Score: 201.835
- Similarity Product: 130.66715325921774

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test