PATENT CLAIM ANALYSIS

Application Number: 16015984
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["424", "134100"]

Abstract:
Formulations and methods of treatment are disclosed for prevention and/or treatment of visual loss from age-related macular degeneration. The disclosed formulations include botulinum neurotoxin. The disclosed formulations may be applied to an intraocular or extraocular region of a patient. If applied to an extra ocular region of a patient, the botulinum-based pharmaceutical formulation may then be transported to the intra-ocular region of the patient, allowing the active ingredient(s) to penetrate into the choroid, neuro-retina, and/or retinal pigment epithelium without direct injection into the eye, eliminating risk of retinal detachment, retinal break, retinal hemorrhage, and blindness. The methods described herein allow for increased blood flow to the choroid, which improves removal of metabolites and intra retinal fluid and also serves to arrest, reverse and/or delay early and later stages of age-related macular degeneration.

Claim (Index 14):
Method of  claim 1  further comprising measuring blood flow of the patient using a laser Doppler technique.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 94.0
- Lexical Diversity: 1.72414
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13695287', '14746221', '14252489', '15485997', '13246527']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7288175204392409
- 35 USC 102 Novelty (BERT): 0.5214372282623516
- Combined Prediction Score: 0.7080794912215519
- Mean Citation Score: 286.177292
- Max Citation Score: 314.0152
- Similarity Product: 207.91938916563987

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test