PATENT CLAIM ANALYSIS

Application Number: 15981142
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "185100"]

Abstract:
The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity.

Claim (Index 25):
The isolated immunoresponsive cell of  claim 22 , wherein the isolated immunoresponsive cell expresses from about 1 to about 4 vector copy numbers/cell of the CAR.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 93.0
- Lexical Diversity: 1.24444
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15368278', '15105082', '15511973', '15866222', '15613800']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8067038102543679
- 35 USC 102 Novelty (BERT): 0.6820001997794207
- Combined Prediction Score: 0.7942334492068732
- Mean Citation Score: 585.336438
- Max Citation Score: 831.91907
- Similarity Product: 656.1059959816325

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test