PATENT CLAIM ANALYSIS

Application Number: 16178497
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-08
Patent Classification: ["424", "206100"]

Abstract:
The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A hemagglutinin trimer and neutralize a group 1 subtype and a group 2 subtype of influenza A virus. The invention also relates to nucleic acids that encode, immortalized B cells and cultured single plasma cells that produce, and to epitopes that bind to such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, treatment and prevention of influenza A virus infection.

Claim (Index 35):
The method of  claim 33 , wherein the antibody or antigen-binding fragment comprises (i) a heavy chain variable region having at least 80% identity to the amino acid sequence set forth in SEQ ID NO: 59 or 55; and (ii) a light chain variable region having at least 80% identity to the amino acid sequence set forth in SEQ ID NO: 57 or 61.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 98.0
- Lexical Diversity: 1.96552
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14233719', '13185157', '12509731', '12509835', '13830367']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8164460831689526
- 35 USC 102 Novelty (BERT): 0.6910125756447444
- Combined Prediction Score: 0.8039027324165318
- Mean Citation Score: 628.720618
- Max Citation Score: 790.9621
- Similarity Product: 673.9885288996219

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test