PATENT CLAIM ANALYSIS

Application Number: 15943058
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "133100"]

Abstract:
Disclosed are methods of influencing, and enhancing, cognitive function and memory by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is improved, in a subject in need thereof, by administering a therapeutically effective amount of Reelin, a Reelin-specific modulator or an agonist of a lipoprotein receptor to the subject. The lipoprotein receptor can be selected from candidates such as ApoER2 and VLDLR. As disclosed herein, agonists of the lipoprotein receptor for use with the inventive method include APC, Sep and Fc-RAP. In addition to administering exogenous Reelin, a Reelin-specific modulator, such as a recombinant Reelin fragment, can be used to increase Reelin levels and/or signaling.

Claim (Index 7):
The method of  claim 5 , wherein the Reelin fragment is administered for less than 1 year, less than 6 months, less than 3 months, less than 1 month, 21 days, less than 1 week, or about 1 day.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 91.0
- Lexical Diversity: 1.77778
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14969959', '13206174', '15763047', '14562401', '15672817']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.733843595330923
- 35 USC 102 Novelty (BERT): 0.5871270893102649
- Combined Prediction Score: 0.7191719447288573
- Mean Citation Score: 429.780664
- Max Citation Score: 706.8937
- Similarity Product: 371.65065578773016

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test