PATENT CLAIM ANALYSIS

Application Number: 16212582
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["544", "279000"]

Abstract:
The present application provides a compound of formula (I) or a salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A, G, M, Q and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders.

Claim (Index 11):
A method of treating a proliferative disorder in a subject comprising administering to the subject a compound of Formula I or a pharmaceutically acceptable salt form thereof, wherein Formula I is: wherein, R 1 , R 2 , and R 11  are independently chosen from H and C 1-6 alkyl optionally substituted by 1-13 R 19 ; R 3  is chosen from H, C 1-6 alkyl optionally substituted by 1-13 R 19 , C 7-11 arylalkyl optionally substituted by 1-9 R 19 , C 6-7 cycloalkylalkyl optionally substituted by 1-6 R 19 , and 6-11 membered heteroarylalkyl optionally substituted by 1-7 R 19 ; R 4 , R 5 , and R 6  are H; R 7  is selected from H and C 1-6 alkyl optionally substituted by 1-3 R 19 ; R 8  is selected from C 2-6 alkynyl optionally substituted by 1-3 R 19 ; R 12 , R 13 , R 14 , and R 15  are independently chosen from H, C 1-6 alkyl optionally substituted by 1-3 R 19 , halogen, \u2014NR 22 R 23 , \u2014NR 24 C(\u2550O)R 20 , \u2014NR 24 C(\u2550O)NR 22 R 23 , \u2014OR 20 , and \u2014S(\u2550O) 2 NR 22 R 23 . R 19  at each occurrence is independently chosen from C 1-6 alkyl, phenyl, C 3-6 cycloalkyl, 3-6 membered heterocycloalkyl, halogen, \u2014C(\u2550O)OR 30  and \u2014OR 30 ; and R 20 , R 22 , R 23 , R 24  and R 30  at each occurrence are independently chosen from H and C 1-6 alkyl.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 98.0
- Lexical Diversity: 1.57447
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15417191', '14668022', '14285007', '14975605', '14038915']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7768703607652054
- 35 USC 102 Novelty (BERT): 0.6449810456527066
- Combined Prediction Score: 0.7636814292539555
- Mean Citation Score: 464.299616
- Max Citation Score: 613.6288
- Similarity Product: 587.9530610931397

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test