PATENT CLAIM ANALYSIS

Application Number: 16313360
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["424", "001110"]

Abstract:
The present invention relates to an aryl ethene derivative, for inhibiting an estrogen-related receptor gamma (ERRγ) activity, a prodrug of same, a solvate of same, a stereoisomer of same or pharmaceutically acceptable salts of same, and a pharmaceutical composition containing same as an active ingredient.

Claim (Index 12):
A kit for treating thyroid cancer, comprising: an arylethene derivative represented by the following Chemical Formula 1: wherein L is (C6-C20)arylene, (C3-C20)heteroarylene, or (C3-C20)fused heterocycle; R 1  is (C3-C20)heterocycloalkyl, (C3-C20)heteroaryl, \u2014O\u2014(CH 2 ) m \u2014R 11 , \u2014(CH 2 ) m \u2014R 12 , \u2014NH\u2014(CH 2 ) m \u2014R 13 , \u2014NHCO\u2014(CH 2 ) n \u2014R 14 , or \u2014SiR 16 R 17 \u2014(CH 2 ) m \u2014R 15 ; R 11  to R 15  are independently of one another (C3-C20)heterocycloalkyl; R 16  and R 17  are independently of each other (C1-C20)alkyl; m is an integer of 1 to 3; n is an integer of 0 or 1; Ar is (C6-C20)aryl or (C3-C20)heteroaryl, in which the aryl or heteroaryl of Ar may be further substituted by one or more selected from the group consisting of hydroxy, halogen, (C1-C20)alkyl, halo(C1-C20)alkyl, (C1-C20)alkoxy, nitro, cyano, \u2014NR 21 R 22 , (C1-C20)alkylcarbonyloxy, (C1-C20)alkylcarbonylamino, guanidino, \u2014SO 2 \u2014R 23  and \u2014OSO 2 \u2014R 24 ; R 21  and R 22  are independently of each other hydrogen, (C1-C20)alkylsulfonyl, or (C3-C20)cycloalkylsulfonyl; R 23  and R 24  are independently of each other (C1-C20)alkyl, halo(C1-C20)alkyl, or (C3-C20)cycloalkyl; R 2  is hydroxy, halogen, (C1-C20)alkylcarbonyloxy, or (C1-C20)alkylsulfonyloxy; the heterocycloalkyl or heteroaryl of R 1  and the heterocycloalkyl of R 11  to R 15  may be further substituted by one or more selected from the group consisting of (C1-C20)alkyl, (C3-C20)cycloalkyl, (C2-C20)alkenyl, amidino, (C1-C20)alkoxycarbonyl, hydroxy, hydroxy(C1-C20)alkyl, and di(C1-C20)alkylamino(C1-C20)alkyl; and the heterocycloalkyl and heteroaryl contains one or more heteroatoms selected from the group consisting of N, O and S, and the heterocycloalkyl is a saturated or unsaturated mono-, bi-, or spirocycle having a carbon atom or nitrogen atom in a ring as a binding site, or a prodrug, solvate, stereoisomer, or pharmaceutically acceptable salt thereof, and radioactive iodine.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 98.0
- Lexical Diversity: 1.43243
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15102968', '12704343', '11829531', '13098247', '14473147']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6765327854263705
- 35 USC 102 Novelty (BERT): 0.521023188494264
- Combined Prediction Score: 0.6609818257331599
- Mean Citation Score: 290.742902
- Max Citation Score: 305.64383
- Similarity Product: 224.41408436057927

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test