PATENT CLAIM ANALYSIS

Application Number: 16019815
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["424", "001650"]

Abstract:
The present invention relates to a method for preparing beads comprising imaging agent. The present invention further provides beads highly useful for medical imaging.

Claim (Index 1):
A method for diagnosing in a subject a pathological condition selected from the group consisting of thrombosis, myocardial ischemia/reperfusion injury, stroke and ischemic brain trauma, neurodegenerative disorders, tumor metastasis and tumor growth, and rheumatoid arthritis, wherein said method comprises the steps of:\n administering to the subject beads comprising fucoidan and an imaging agent; and detecting the beads within the subject with an imaging technique, wherein the beads are obtained by a method comprising the following steps: i) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of an imaging agent and an amount of a cross linking agent; ii) dispersing said alkaline aqueous solution into an hydrophobic phase comprising a surfactant in order to obtain w/o emulsion; iii) transforming the w/o emulsion into beads by placing said w/o emulsion at a temperature from about 4\u00b0 C. to about 80\u00b0 C. for a sufficient time to allow the cross-linking of said amount of polysaccharide; and optionally iv) incubating the beads obtained in step iii) with a solution of fucoidan to graft fucoidan on the surface of the beads, wherein said polysaccharide is selected from the group consisting of dextran, pullulan, fucoidan, agar, alginic acid, hyaluronic acid, inulin, heparin, chitosan and mixtures thereof; and wherein the presence of fucoidan is due to:\n the presence of fucoidan in the alkaline aqueous solution of step i); and/or \n the incubation of the beads with a solution of fucoidan during step iv).

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.36842
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13819437', '15657868', '14728412', '14267791', '12449712']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.709758499081212
- 35 USC 102 Novelty (BERT): 0.5114918806645298
- Combined Prediction Score: 0.6899318372395438
- Mean Citation Score: 214.864228
- Max Citation Score: 281.4419
- Similarity Product: 191.8754476012468

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test