PATENT CLAIM ANALYSIS

Application Number: 16126210
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["540", "455000"]

Abstract:
Disclosed herein, inter alia, are compounds and methods of using the same for modulating the activity of mTORC1.

Claim (Index 62):
The compound of  claim 57 , wherein\n L 2  is R 26 -substituted or unsubstituted 2 to 8 membered heteroalkylene; L 3  is a R 29 -substituted or unsubstituted 5 to 10 membered heteroarylene; L 4  is a R 32 -substituted or unsubstituted 2 to 20 membered heteroalkylene; L 5  is a R 35 -substituted or unsubstituted 2 to 20 membered heteroalkylene; R 26  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 27 -substituted or unsubstituted alkyl, R 27 -substituted or unsubstituted heteroalkyl, R 27 -substituted or unsubstituted cycloalkyl, R 27  substituted or unsubstituted heterocycloalkyl, R 27 -substituted or unsubstituted aryl, or R 27 -substituted or unsubstituted heteroaryl; R 27  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 28 -substituted or unsubstituted alkyl, R 28 -substituted or unsubstituted heteroalkyl, R 28 -substituted or unsubstituted cycloalkyl, R 28 -substituted or unsubstituted heterocycloalkyl, R 28 -substituted or unsubstituted aryl, or R 28 -substituted or unsubstituted heteroaryl; R 29  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 30 -substituted or unsubstituted alkyl, R 30 -substituted or unsubstituted heteroalkyl, R 30 -substituted or unsubstituted cycloalkyl, R 30  substituted or unsubstituted heterocycloalkyl, R 30 -substituted or unsubstituted aryl, or R 30 -substituted or unsubstituted heteroaryl; R 30  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 31 -substituted or unsubstituted alkyl, R 31 -substituted or unsubstituted heteroalkyl, R 31 -substituted or unsubstituted cycloalkyl, R 31 -substituted or unsubstituted heterocycloalkyl, R 31 -substituted or unsubstituted aryl, or R 31 -substituted or unsubstituted heteroaryl; R 32  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 33 -substituted or unsubstituted alkyl, R 33 -substituted or unsubstituted heteroalkyl, R 33 -substituted or unsubstituted cycloalkyl, R 33  substituted or unsubstituted heterocycloalkyl, R 33 -substituted or unsubstituted aryl, or R 33 -substituted or unsubstituted heteroaryl; R 33  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 34 -substituted or unsubstituted alkyl, R 34 -substituted or unsubstituted heteroalkyl, R 34 -substituted or unsubstituted cycloalkyl, R 34 -substituted or unsubstituted heterocycloalkyl, R 34 -substituted or unsubstituted aryl, or R 34 -substituted or unsubstituted heteroaryl; R 35  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 36 -substituted or unsubstituted alkyl, R 36 -substituted or unsubstituted heteroalkyl, R 36 -substituted or unsubstituted cycloalkyl, R 36  substituted or unsubstituted heterocycloalkyl, R 36 -substituted or unsubstituted aryl, or R 36 -substituted or unsubstituted heteroaryl; R 36  is independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , R 37 -substituted or unsubstituted alkyl, R 37 -substituted or unsubstituted heteroalkyl, R 37 -substituted or unsubstituted cycloalkyl, R 37 -substituted or unsubstituted heterocycloalkyl, R 37 -substituted or unsubstituted aryl, or R 37 -substituted or unsubstituted heteroaryl; and R 28 , R 31 , R 34 , and R 37  are independently oxo, halogen, \u2014CF 3 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHNH 2 , \u2014ONH 2 , \u2014NHC\u2550(O)NHNH 2 , \u2014NHC\u2550(O) NH 2 , \u2014NHSO 2 H, \u2014NHC\u2550(O)H, \u2014NHC(O)\u2014OH, \u2014NHOH, \u2014OCF 3 , \u2014OCHF 2 , unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, or unsubstituted heteroaryl.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 97.0
- Lexical Diversity: 1.16667
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15455727', '15614278', '16301200', '14849428', '15757238']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7162247213594365
- 35 USC 102 Novelty (BERT): 0.6944234912268787
- Combined Prediction Score: 0.7140445983461807
- Mean Citation Score: 500.237734
- Max Citation Score: 790.2497599999997
- Similarity Product: 667.545010383806

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test