PATENT CLAIM ANALYSIS

Application Number: 16254795
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["250", "288000"]

Abstract:
This disclosure provides quantitative, rapid, and reliable LC-MS/MS methods for analyzing panels of pesticides and mycotoxins in various samples, including very hydrophobic and chlorinated compounds normally analyzed on a GC-MS/MS system. The methods can be carried out using a single instrument and can detect and quantify levels of the pesticides and mycotoxins that are well below action limits specified by U.S. states (e.g., California) and other countries (e.g., Canada) for these compounds in  cannabis  products.

Claim (Index 1):
A triple quadrupole mass spectrometer comprising:\n (a) an electrospray ionization (ESI) source, wherein the triple quadrupole mass spectrometer is configured to detect a Multiple Reaction Monitoring (MRM) transition selected from the group consisting of MRM transitions in Group A:\n 890.5>145.0 (abamectin); \n 890.5>567.2 (abamectin); \n 890.5>305.1 (abamectin); \n 184.0>49.0 (acephate); \n 184.0>95.0 (acephate); \n 402.2>343.1 (acequinocyl); \n 402.2>189 (acequinocyl); \n 208.0>116.0 (aldicarb); \n 208.0>89.0 (aldicarb); \n 343.0>272.0 (boscalid); \n 316.9>263.9 (captan); \n 316.9>235.9 (captan); \n 318.9>265.9 (captan); \n 318.9>237.9 (captan); \n 409.0>59.1 (chlorfenapyr); \n 407.0>59.1 (chlorfenapyr); \n 424.0>59.1 (chlorfenapyr); \n 426.0>59.1 (chlorfenapyr); \n 349.9>321.9 (chlorpyrifos); \n 317.2>121.0 (cinerin-I); \n 317.2>107.0 (cinerin-I); \n 317.2>149.0 (cinerin-I); \n 361.2>149.0 (cinerin-II); \n 361.2>213.0 (cinerin-II); \n 363.0>306.9 (coumaphos); \n 363.0>334.9 (coumaphos); \n 363.0>226.9 (coumaphos); \n 453.1>193.0 (cyfluthrin); \n 451.1>127.0 (cyfluthrin); \n 451.1>191.0 (cyfluthrin); \n 435.1>193.1 (cypermethrin); \n 435.1>127.0 (cypermethrin); \n 433.1>127.0 (cypermethrin); \n 161.1>44.0 (daminozide); \n 161.1>45.0 (daminozide); \n 165.1>147.0 (daminozide-D 4 ); \n 220.9>127.0 (dichlorvos); \n 388.1>301.0 (dimethomorph); \n 388.1>273.0 (dimethomorph); \n 394.2>359.1 (etofenprox); \n 302.1>55.0 (fenhexamid); \n 302.1>97.0 (fenhexamid); \n 302.1>256.0 (fenoxycarb); \n 422.2>138.0 (fenpyroximate); \n 435.0>250.0 (fipronil); \n 435.0>330.0 (fipronil); \n 247.1>126.0 (fludioxonil); \n 247.1>180.0 (fludioxonil); \n 297.0>41.0 (imazalil); \n 260.2>213 (imidacloprid-D 4 ); \n 331.0>163.0 (jasmolin I); \n 375.2>163.0 (jasmolin II); \n 375.2>213.0 (jasmolin II); \n 331.0>285.0 (malathion); \n 280.2>248.1 (metalaxyl); \n 242.0>127.0 (mevinphos); \n 242.0>109.0 (mevinphos); \n 225.0>127.0 (mevinphos); \n 225.0>109.0 (mevinphos); \n 298.0>70.0 (myclobutanil D 9 ); \n 276.2>98.0 (n-octyl bicycloheptene dicarboximide (MGK-264); \n 380.8>127.0 (naled); \n 382.8>127.0 (naled); \n 380.8>109.0 (naled); \n 318.0>133.0 (phosmet); \n 301.2>123 (prallethrin); \n 344.1>69.0 (propiconazole); \n 344.1>161.0 (propiconazole); \n 329.2>143.0 (pyrethrin-I); \n 373.2>143.0 (pyrethrin-II); \n 378.0>160.0 (pyridaben-D 13 ); \n 748.5>98.0 (spinetoram); \n 748.5>142.0 (spinetoram); \n 746.5>98.0 (spinosyn D); \n 746.5>142.0 (spinosyn D); \n 374.2>216.0 (spirotetramat); \n 296.0>215.0 (thiamethoxam-D 4 ); \n 343.1>151.0 (thiophanate methyl); and \n 343.1>268.0 (thiophanate methyl); or \n (b) an atmospheric chemical ionization (APCI) source, wherein the triple quadrupole mass spectrometer is configured to detect an MRM transition selected from the group consisting of MRM transitions in Group B:\n 439.8>35.1 (chlordane); \n 441.8>35.1 (chlordane); \n 275.8>35.1 (PCNB); \n 273.8>35.1 (PCNB); \n 275.8>201.9 (PCNB); \n 216.8>35.0 (etridiazole); \n 218.8>35.0 (etridiazole); \n 346.9>79.0 (chlorfenapyr); and \n 348.9>81.0 (chlorfenapyr); or \n (c) the ESI source and the APCI source.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 99.0
- Lexical Diversity: 1.36508
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13881848', '14340135', '14715153', '13514892', '13338123']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6772956506253828
- 35 USC 102 Novelty (BERT): 0.4922772652995139
- Combined Prediction Score: 0.658793812092796
- Mean Citation Score: 200.933838
- Max Citation Score: 215.98889
- Similarity Product: 145.9612806921357

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test