PATENT CLAIM ANALYSIS

Application Number: 16016917
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-05
Patent Classification: ["544", "328000"]

Abstract:
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

Claim (Index 179):
The method of  claim 175 , wherein:\n R 1  is \u2014H; R 2  is \u2014H, \u2014CH 3 , \u2014CH 2 OH, or \u2014NH 2 ; R 3  is \u2014H, \u2014-F, \u2014Cl, C 1 -C 4  alkyl, or C 1 -C 4  haloalkyl; Z 1  is \u2014H, \u2014F, or \u2014Cl; Z 2  is \u2014H or C 1 -C 6  alkyl optionally substituted with one or more substituents independently selected from the group consisting of halogen, cyano, hydroxy, and \u2014O(C 1 -C 4  alkyl); Z 3  is \u2014H or C 1 C 6  alkyl optionally substituted with one or more substituents independently selected from the group consisting of halogen, cyano, hydroxy, and \u2014O(C 1 -C 4  alkyl); R 5  is:\n i) \u2014H; \n ii) an optionally substituted C 1 -C 6  alkyl group; \n iii) an optionally substituted C 3 -C 7  non-aromatic carbocycle; or \n iv) an optionally substituted 4-7 membered non-aromatic heterocycle; or optionally, together with R and the nitrogen atom to which it is attached, form a 5-7 membered, optionally substituted non-aromatic heterocycle; and \n said alkyl group represented by R 5  is optionally substituted with one or more substituents independently selected from the group consisting of halogen, cyano, hydroxy, oxo, \u2014NH 2 , \u2014NH(C 1 -C 4  alkyl), \u2014N(C 1 -C 4  alkyl) 2 , \u2014OCO(C 1 -C 4  alkyl), \u2014CO(C 1 -C 4  alkyl), \u2014CO 2 H, \u2014CO 2 (C 1 -C 4  alkyl), C 1 -C 4  alkoxy, an optionally substituted C 3 -C 7  non-aromatic carbocycle , an optionally substituted 4-7 membered non-aromatic heterocycle; and wherein each of said carbocycles and heterocycles represented by R 5 , and referred to for the substituents of the C 1 -C 6  alkyl group represented by R 5  is independently and optionally substituted with one or more substituents independently selected from the group consisting of halogen, cyano, hydroxy, oxo, C 1 -C 4  alkyl, \u2014O(C 1 -C 4  alkyl), \u2014NH 2 , \u2014NH(C 1 -C 4  alkyl), \u2014N(C 1 -C 4  alkyl) 2 , \u2014C(O)(C 1 -C 4  alkyl), \u2014OC(O)(C 1 -C 4  alkyl), \u2014C(O)O(C 1 C 4  alkyl) and CO 2 H, wherein each of said alkyl groups is optionally and independently substituted with one or more substituents independently selected from the group consisting of halogen, cyano, hydroxy, oxo, \u2014NH 2 , \u2014NH(C 1 -C 4  alkyl), \u2014N(C 1 -C 4  alkyl) 2 , \u2014OCO(C 1 -C 4  alkyl), \u2014O(C 1 -C 4  alkyl), \u2014CO 2 H, \u2014CO 2 (C 1 -C 4  alkyl), and C 1 -C 4  alkoxy.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 94.0
- Lexical Diversity: 2.60377
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14305393', '15718186', '15299757', '14098867', '14929634']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8902230161193824
- 35 USC 102 Novelty (BERT): 0.6686188176190971
- Combined Prediction Score: 0.8680625962693538
- Mean Citation Score: 651.808932
- Max Citation Score: 787.6186
- Similarity Product: 643.662626966548

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test