PATENT CLAIM ANALYSIS

Application Number: 16298308
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["800", "006000"]

Abstract:
Genetically modified mice are provided that express human λ variable (hVλ) sequences, including mice that express hVλ sequences from an endogenous mouse λ light chain locus, mice that express hVλ sequences from an endogenous mouse κ light chain locus, and mice that express hVλ sequences from a transgene or an episome wherein the hVλ sequence is linked to a mouse constant sequence. Mice are provided that are a source of somatically mutated human λ variable sequences useful for making antigen-binding proteins. Compositions and methods for making antigen-binding proteins that comprise human λ variable sequences, including human antibodies, are provided.

Claim (Index 25):
The method of  claim 23 , wherein the one or more unrearranged human V\u03bb gene segments of (i) and the one or more unrearranged human J\u03bb gene segments of (ii) are operably linked to the one or more human C\u03bb gene segments of (iii).

Metadata:
- Claim Count in Document: 85.0
- Percentile: 99.0
- Lexical Diversity: 2.13725
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14636784', '13945573', '13166171', '14638429', '14943890']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8757134462542873
- 35 USC 102 Novelty (BERT): 0.6629098688818915
- Combined Prediction Score: 0.8544330885170477
- Mean Citation Score: 1051.25974
- Max Citation Score: 1062.2339
- Similarity Product: 665.7330554229497

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test