PATENT CLAIM ANALYSIS

Application Number: 15989860
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-03
Patent Classification: ["424", "133100"]

Abstract:
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, lung, breast, mouse, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervix, ovary, and/or prostate cancer.

Claim (Index 17):
The isolated antibody or antigen-binding fragment of  claim 16  wherein the antibody or the antigen binding fragment further comprising H-FR1, H-FR2, H-FR3, and HFR4 selected from (i)-(iv) as set forth in Table I ( FIG. 16 ):\n (i) H-FR1 selected from SEQ ID NO:79, SEQ ID NO: 83, SEQ ID NO:85 or SEQ ID NO: 87; \n (ii) H-FR2 selected from SEQ ID NO:81, SEQ ID NO: 84, SEQ ID NO:86 or SEQ ID NO: 88; \n (iii) H-FR3 selected from SEQ ID NO:89, SEQ ID NO: 92, SEQ ID NO:94 or SEQ ID NO: 96; \n (iv) H-FR4 selected from SEQ ID NO:91, SEQ ID NO: 93, SEQ ID NO:95 or SEQ ID NO: 97, respectively; and comprising L-FR1, L-FR2, L-FR3 and L-FR4 selected from (v)-(viii): \n (v) L-FR1 selected from SEQ ID NO:98, SEQ ID NO: 102, SEQ ID NO:104 or SEQ ID NO: 106; \n (vi) L-FR2 selected from SEQ ID NO:100, SEQ ID NO: 103, SEQ ID NO:105 or SEQ ID NO: 107; \n (vii) L-FR3 selected from SEQ ID NO:108, SEQ ID NO: 111, SEQ ID NO:113 or SEQ ID NO: 114, \n (viii) L-FR4 selected from SEQ ID NO:110 or SEQ ID NO: 112, respectively.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 93.0
- Lexical Diversity: 1.61667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14599174', '14798312', '15011544', '15011543', '15683685']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7423802483590698
- 35 USC 102 Novelty (BERT): 0.7117254998090935
- Combined Prediction Score: 0.7393147735040723
- Mean Citation Score: 719.916168
- Max Citation Score: 882.62274
- Similarity Product: 742.3133618551111

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test