PATENT CLAIM ANALYSIS

Application Number: 16033618
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "199000"]

Abstract:
The present invention relates to mutants of a parent  Trichoderma  strain, comprising a polynucleotide encoding a polypeptide and one or more genes selected from the group consisting of a peptaibol synthetase gene, a paracelsin synthetase gene, a first terpene cyclase gene, a second terpene cyclase gene, and a third terpene cyclase gene, wherein one or more of the genes are modified rendering the mutant strain deficient in the production of one or more of the enzymes selected from the group consisting of a peptaibol synthetase, a paracelsin synthetase, a first terpene cyclase, a second terpene cyclase, and a third terpene cyclase compared to the parent  Trichoderma  strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.

Claim (Index 20):
A mutant of a parent  Trichoderma  strain, comprising a polynucleotide encoding a heterologous polypeptide and a peptaibol synthetase gene and a paracelsin synthetase gene, wherein the peptaibol synthetase gene and the paracelsin synthetase gene are modified rendering the mutant strain deficient in the production of a peptaibol synthetase and a paracelsin synthetase compared to the parent  Trichoderma reesei  strain when cultivated under identical conditions, wherein the heterologous polypeptide is selected from the group consisting of an acetylmannan esterase, acetylxylan esterase, am inopeptidase, alpha-amylase, arabinanase, arabinofuranosidase, carbohydrase, carboxypeptidase, catalase, cellobiohydrolase, cellulase, cellulose inducing protein, chitinase, coumaric acid esterase, cyclodextrin glycosyltransferase, cutinase, cyclodextrin glycosyltransferase, deoxyribonuclease, endoglucanase, esterase, expansin, feruloyl esterase, AA9 polypeptide, alpha-galactosidase, beta-galactosidase, glucocerebrosidase, glucose oxidase, alpha-glucosidase, beta-glucosidase, glucuronidase, glucuronoyl esterase, haloperoxidase, hemicellulase, invertase, isomerase, laccase, ligase, lipase, mannanase, mannosidase, mutanase, oxidase, pectinolytic enzyme, peroxidase, phospholipase, phytase, phenoloxidase, polyphenoloxidase, proteolytic enzyme, ribonuclease, swollenin, alpha-1,6-transglucosidase, transglutaminase, urokinase, xylanase, and beta-xylosidase.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 95.0
- Lexical Diversity: 2.57143
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14663118', '13516433', '09482788', '14402837', '15418280']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5523868000086003
- 35 USC 102 Novelty (BERT): 0.5086342401621782
- Combined Prediction Score: 0.5480115440239581
- Mean Citation Score: 261.73350400000004
- Max Citation Score: 292.9541
- Similarity Product: 243.5004456165433

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test