PATENT CLAIM ANALYSIS

Application Number: 16037368
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "249000"]

Abstract:
The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as TLR7/8 antagonists.

Claim (Index 1):
A compound of formula I, wherein, Ring A is aryl or heteroaryl having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; each of which is optionally substituted; Ring B is heteroaryl having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; each of which is optionally substituted; R 1  is \u2014CH 3 , \u2014CF 3  or \u2014CN; each R 2  is independently \u2014H, \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; each R 3  is independently \u2014H, \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; each R 4  is independently \u2014H, \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRC(O)OR, \u2014NRSO 2 R, or \u2014N(R) 2 ; each R 5  is independently \u2014H, \u2014R, halogen, -haloalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; each R is independently hydrogen, C 1-6  aliphatic, C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; or two R groups on the same atom are taken together with the atom to which they are attached to form a C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; k is 0, 1 or 2; n is 0, 1, or 2; p is 0, 1, or 2; r is 1, 2, or 3; and t is 1, 2, or 3; wherein k is 0 when attached to nitrogen; and k is 1 or 2 when attached to carbon.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 95.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15381406', '15620049', '15016569', '15680683', '15267606']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7975485082866143
- 35 USC 102 Novelty (BERT): 0.5514856920800074
- Combined Prediction Score: 0.7729422266659536
- Mean Citation Score: 329.576652
- Max Citation Score: 412.4425
- Similarity Product: 344.9038389840722

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test