PATENT CLAIM ANALYSIS

Application Number: 15881919
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "001300"]

Abstract:
This disclosure features compounds that are useful as pro-drugs of epoxy ketone protease inhibitors.

Claim (Index 24):
The compound of  claim 22 , wherein R 16  is \u2014Y\u2032 p \u2014Z\u2032; wherein\n Y\u2032 is a divalent spacer which comprises of one or more of the following moieties (e.g., comprise 1, 2, 3, 4, or 5 of the following moieties; e.g., comprise 1, 2, or 3 of the following moieties; e.g., consist of 1, 2, 3, 4, or 5 of the following moieties; e.g., consist of 1, 2, or 3 of the following moieties): heteroatom (e.g., N, O, or S), alkylene chain, heteroalkylene chain, C 6-10 arylene, heteroarylene from 5-10 ring atoms (wherein from 1-3 of the ring atoms are independently selected from N, NH, N\u2014C 1 -C 6  alkyl, O, and S), polyheteroalkylene chain, alkenylene chain, \u2014OC(\u2550O)\u2014, \u2014C(\u2550O)O\u2014, \u2014NHC(\u2550O)\u2014, and \u2014C(\u2550O)NH\u2014; Z\u2032 is conjugate for enhancing solubility, stability, half-life, permeability, volume of distribution, and/or target specificity, which comprises of one or more of the following moieties (e.g., comprise 1, 2, 3, 4, or 5 of the following moieties; e.g., comprise 1, 2, or 3 of the following moieties; e.g., consist of 1, 2, 3, 4, or 5 of the following moieties; e.g., consist of 1, 2, or 3 of the following moieties): alkylene chain, heteroalkylene chain, polyheteroalkylene chain, cyclodextrin, \u2014OC(\u2550O)\u2014, \u2014C(\u2550O)O\u2014, \u2014NHC(\u2550O)\u2014, \u2014C(\u2550O)NH\u2014, \u2014C(\u2550O)\u2014, NH 2 ;\n p is 0 or 1.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 86.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13938160', '14041953', '15065347', '15602823', '15651687']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8046144765645314
- 35 USC 102 Novelty (BERT): 0.6675819554649092
- Combined Prediction Score: 0.7909112244545692
- Mean Citation Score: 569.07662
- Max Citation Score: 793.8515
- Similarity Product: 601.9905624452531

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test