PATENT CLAIM ANALYSIS

Application Number: 16176137
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "04400A"]

Abstract:
The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.

Claim (Index 4):
The composition of  claim 3 , wherein at least three of the uracil nucleic acids in the nucleotide sequence are 5-halouracils.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 97.0
- Lexical Diversity: 1.70492
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15845573', '15508857', '13808741', '12740256', '12149725']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7955768082630141
- 35 USC 102 Novelty (BERT): 0.5278492400530999
- Combined Prediction Score: 0.7688040514420227
- Mean Citation Score: 313.207636
- Max Citation Score: 332.1092
- Similarity Product: 208.52440020861627

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test