PATENT CLAIM ANALYSIS

Application Number: 16159238
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["424", "400000"]

Abstract:
Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.

Claim (Index 12):
The method of  claim 11 , wherein the gelatin sponge carries at least one bFGF homologue selected from the group consisting of:\n (i) an amino acid sequence of a bFGF produced in a mammal that has 1 to 6 amino acids substituted by other kinds of amino acids and possessing the bioactivity of bFGF; (ii) a polypeptide wherein a supplementary amino acid segment is added to the N-terminus and/or C-terminus of a bFGF produced in a mammal, wherein the supplementary amino acid segment consists of 1 to 12 amino acids and does not affect the biological activity of bFGF; and (iii) a polypeptide wherein a supplementary amino acid segment is added to the N-terminus and/or C-terminus of a polypeptide of (i), wherein the supplementary amino acid segment consists of 1 to 12 amino acids and does not affect the biological activity of the polypeptide of (i).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 97.0
- Lexical Diversity: 1.53226
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13001318', '14849001', '14131710', '12820864', '14003802']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.802730312187847
- 35 USC 102 Novelty (BERT): 0.5627203375863157
- Combined Prediction Score: 0.7787293147276938
- Mean Citation Score: 338.4124520000001
- Max Citation Score: 501.7477
- Similarity Product: 316.4885171362996

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test