PATENT CLAIM ANALYSIS

Application Number: 16186879
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-02
Patent Classification: ["514", "001400"]

Abstract:
The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as obesity, diabetes mellitus and sexual dysfunction.

Claim (Index 2):
A compound according  claim 1  wherein the compound is\n cyclo[Hydantoin(C(O)-(Cys-D-Ala))-His-D-Phe-Arg-Trp-Cys]-NH 2 ; (SEQ ID NO:1) \n cyclo[Hydantoin(C(O)-(hCys-D-Ala))-His-D-Phe-Arg-Trp-Cys]-NH 2 ; (SEQ ID NO:2) \n cyclo[Hydantoin(C(O)-(Cys-D-Ala))-His-D-2-Nal-Arg-Trp-Cys]-NH 2 ; (SEQ ID NO:1) \n cyclo[Hydantoin(C(O)-(hCys-D-Ala))-His-D-2-Nal-Arg-Trp-Cys]-NH 2 ; (SEQ ID NO:2) \n cyclo[Hydantoin(C(O)-(Asp-D-Ala))-His-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:3) \n cyclo[Hydantoin(C(O)-(Asp-D-Ala))-His-D-Phe-Arg-Trp-Orn]-NH 2 ; (SEQ ID NO:4) \n cyclo[Hydantoin(C(O)-(Asp-D-Ala))-His-D-Phe-Arg-Trp-Dab]-NH 2 ; (SEQ ID NO:4) \n cyclo[Hydantoin(C(O)-(Asp-D-Ala))-His-D-Phe-Arg-Trp-Dap]-NH 2 ; (SEQ ID NO:4) \n cyclo[Hydantoin(C(O)-(Asp-His))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:5) \n cyclo[Hydantoin(C(O)-(Asp-His))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:5) \n cyclo[Hydantoin(C(O)-(Asp-A3c))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:6) \n cyclo[Hydantoin(C(O)-(Asp-A5c))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:7) \n cyclo[Hydantoin(C(O)-(Asp-A6c))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:8) \n cyclo[Hydantoin(C(O)-(Asp-A3c))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:6) \n cyclo[Hydantoin(C(O)-(Asp-A5c))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:7) \n cyclo[Hydantoin(C(O)-(Asp-A6c))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:8) \n cyclo[Hydantoin(C(O)-(Asp-Aic))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:9) \n cyclo[Hydantoin(C(O)-(Asp-Apc))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:10) \n cyclo[Hydantoin(C(O)-(Asp-Aic))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:9) \n cyclo[Hydantoin(C(O)-(Asp-Apc))-D-2-Nal-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:10) \n cyclo[Hydantoin(C(O)-(Glu-D-Ala))-His-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:68) \n cyclo[Hydantoin(C(O)-(Glu-D-Ala))-His-D-Phe-Arg-Trp-Orn]-NH 2 ; (SEQ ID NO:11) \n cyclo[Hydantoin(C(O)-(Glu-D-Ala))-His-D-Phe-Arg-Trp-Dab]-NH 2 ; (SEQ ID NO:11) \n cyclo[Hydantoin(C(O)-(Glu-D-Ala))-His-D-Phe-Arg-Trp-Dap]-NH 2 ; (SEQ ID NO:11) \n cyclo[Hydantoin(C(O)-(Glu-His))-D-Phe-Arg-Trp-Dap]-NH 2 ; (SEQ ID NO:12) or \n cyclo[Hydantoin(C(O)-(Glu-His))-D-Phe-Arg-Trp-Lys]-NH 2 ; (SEQ ID NO:61) \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 98.0
- Lexical Diversity: 1.46875
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12602010', '14024961', '13074565', '11988468', '15055873']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8814810276695982
- 35 USC 102 Novelty (BERT): 0.6491053631796748
- Combined Prediction Score: 0.8582434612206059
- Mean Citation Score: 625.486862
- Max Citation Score: 672.6033
- Similarity Product: 582.0023524085818

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test