PATENT CLAIM ANALYSIS

Application Number: 15962645
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-09
Patent Classification: ["514", "510000"]

Abstract:
The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify miRNAs that modulate HIV infection and identifying the specific pathways, nucleic acids and/or polypeptides that are targeted by the miRNAs. The invention further provides for the identification and screening of anti-HIV pharmaceutical compounds having known activity against the specific pathways, nucleic acids and/or polypeptides that are targeted by the miRNAs for efficacy in the treatment of HIV. The invention also provides for the use of miRNA mimics, miRNA inhibitors and pharmaceutical compounds (including oncology drugs and kinase inhibitors) in the treatment and/or prevention of HIV infection.

Claim (Index 11):
The method of  claim 1 , wherein the anti-cancer compound is temozolomide.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 91.0
- Lexical Diversity: 2.12308
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15694084', '13378754', '11545280', '14472987', '13260904']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7435990108472315
- 35 USC 102 Novelty (BERT): 0.561287760682544
- Combined Prediction Score: 0.7253678858307627
- Mean Citation Score: 283.125228
- Max Citation Score: 465.68506
- Similarity Product: 272.4021289067984

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test