PATENT CLAIM ANALYSIS

Application Number: 16260387
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["205", "775000"]

Abstract:
A method of detecting a state of a lipid membrane in a cell of a nanopore based sequencing chip is disclosed. A lipid membrane is coupled with an integrating capacitor, wherein the lipid membrane is between a working electrode and a counter electrode. An alternating current (AC) voltage is applied to the counter electrode. A voltage across the integrating capacitor is periodically sampled by an analog-to-digital converter (ADC). A change in the sampled voltage across the integrating capacitor in response to an intermediate change in the AC voltage is determined. A state of the lipid membrane is determined based on the determined change in the sampled voltage across the integrating capacitor in response to the intermediate change in the AC voltage.

Claim (Index 11):
A system for detecting a state of a lipid membrane in a cell of a nanopore based sequencing chip, comprising:\n an integrating capacitor; a working electrode electrically coupled to the integrating capacitor; a counter electrode; a surface configured to support a lipid membrane between the working electrode and the counter electrode such that the lipid membrane is electrically coupled with the integrating capacitor; an alternating current (AC) voltage source configured to apply an AC voltage to the counter electrode; an analog measurement circuitry configured to periodically sample a voltage across the integrating capacitor; and a processor or a circuitry configured to: determine a change in the sampled voltage across the integrating capacitor in response to an intermediate change in the AC voltage; and detect a state of the lipid membrane based on the determined change in the sampled voltage across the integrating capacitor in response to the intermediate change in the AC voltage.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 2.58824
- Patent Class: 205.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15715669', '15085700', '16186894', '15630342', '15085713']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7086689062549962
- 35 USC 102 Novelty (BERT): 0.6127750970080372
- Combined Prediction Score: 0.6990795253303004
- Mean Citation Score: 347.888724
- Max Citation Score: 547.5157
- Similarity Product: 504.9361574862898

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test