PATENT CLAIM ANALYSIS

Application Number: 16003994
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "183000"]

Abstract:
Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.

Claim (Index 13):
A method of treating hypertension in a subject comprising administering to that subject a therapeutically effective amount of a stable oral liquid formulation, the stable oral liquid formulation comprising:\n (i) about 10% to about 25% (w/w of solids) enalapril or a pharmaceutically acceptable salt or solvate thereof; (ii) a buffer comprising about 17% to about 47% (w/w of solids) citric acid and about 1% to about 11% (w/w of solids) sodium citrate; (iii) about 3% to about 25% (w/w of solids) sodium benzoate; and (iv) water;\n wherein the formulation is stable at about 5\u00b13\u00b0 C. for at least 12 months; and \n wherein the stable oral liquid formulation has about 95% w/w or greater of the initial enalapril amount and about 5% w/w or less total impurity or related substances at the end of the given storage period.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 94.0
- Lexical Diversity: 1.27586
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15802341', '15613622', '15081603', '15483691', '15268095']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.780138598847363
- 35 USC 102 Novelty (BERT): 0.5905042420466391
- Combined Prediction Score: 0.7611751631672906
- Mean Citation Score: 413.644672
- Max Citation Score: 461.79395
- Similarity Product: 411.1931929035664

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test