PATENT CLAIM ANALYSIS

Application Number: 15760836
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["435", "006110"]

Abstract:
The invention relates to a method for confirming an amplified nucleic acid target sequence (target sequence), preferably from human samples, during a multiplication reaction in a collective and continuous reaction batch as a one-pot process, wherein the confirmation of the target sequence amplification product is obtained by means of a hapten-pair-marked artificial template amplification product. The artificial template sequence is amplified and optionally marked by means of the 5′-cleavage products of the at least one target-sequence-specific FEN probe. The 5′-cleavage product of the at least one target-sequence-specific FEN probe is obtained only if the FEN probe hybridizes, by means of the target-sequence-specific 3′ sequence thereof, to a complementary sequence segment of the at least one target sequence. The detection of the obtained plurality of template amplification products occurs distinctly and preferably by means of immunochromatographic methods.

Claim (Index 8):
The confirmation assay of  claim 1 , wherein:\n the amplification of the at least one artificial matrix sequence is carried out using at least one labelled 5\u2033-cleavage product (S  1-n ) of the at least one FEN probe and at least one further labelled 5\u2033-cleavage product of the second FEN probe or of at least one further labelled primer (M1), the labelling of the at least one artificial matrix sequence with the specific hapten pair is carried out during amplification, and at least one labelled double strand of the at least one matrix sequence amplification product having one hapten of the specific hapten pair at the respective strand is obtained.

Metadata:
- Claim Count in Document: 25.0
- Percentile: 90.0
- Lexical Diversity: 2.13043
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11150775', '11106237', '11607341', '11476893', '11286573']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6047434824862045
- 35 USC 102 Novelty (BERT): 0.5150851145643065
- Combined Prediction Score: 0.5957776456940147
- Mean Citation Score: 266.865404
- Max Citation Score: 275.5055
- Similarity Product: 187.25974647140487

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test