PATENT CLAIM ANALYSIS

Application Number: 15888959
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "023000"]

Abstract:
The present invention relates to methods of diagnosing, monitoring, and treating elastin fiber injuries. In additional preferred embodiments, the present invention relates to methods of validating candidate compounds for use in treating chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, refractory asthma, and other related diseases. Examples of such methods include determining if the candidate compound decreases the degradation of elastic fiber in a patient administered the candidate compound by measuring, using mass spectrometry employing an internal standard, a marker of elastic fiber degradation in a sample of a body fluid or a tissue of the patient. The invention provides that a decrease in the presence of the marker compared to a control validates that the candidate compound is effective to treat, prevent, or ameliorate the disease.

Claim (Index 28):
The method according to  claim 25 , wherein the disease is COPD.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 1.8
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13836332', '10253756', '13445763', '11041589', '10572872']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5613809081262794
- 35 USC 102 Novelty (BERT): 0.629077156795648
- Combined Prediction Score: 0.5681505329932163
- Mean Citation Score: 335.9662160000001
- Max Citation Score: 829.55524
- Similarity Product: 502.9240350291062

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test