PATENT CLAIM ANALYSIS

Application Number: 15760413
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["530", "353000"]

Abstract:
Provided herein are polypeptides which include tenth fibronectin type III domains ( 10 Fn3) that binds to serum albumin. Also provided are fusion molecules comprising a serum albumin binding  10 Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.

Claim (Index 1):
A polypeptide comprising a fibronectin type III tenth ( 10 Fn3) domain, wherein the  10 Fn3 domain binds to human serum albumin (HSA) with a K D  or 1 \u03bcM or less and comprises AB, BC, CD, DE, EF, and FG loops, wherein the CD loop has 1, 2, or 3 amino acid substitutions, and the FG loop optionally has 1, 2, or 3 amino acid substitutions, relative to the CD and FG loops of a  10 Fn3 domain comprising the amino acid sequence set forth in SEQ ID NO: 23, and wherein the serum half-life of a moiety (e.g., polypeptide) that is linked to the  10 Fn3 domain is extended relative to that of the moiety that is not linked to the  10 Fn3 domain.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 90.0
- Lexical Diversity: 1.21053
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14553379', '14481641', '15282277', '13579204', '15127166']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7137065023498563
- 35 USC 102 Novelty (BERT): 0.5523473245612199
- Combined Prediction Score: 0.6975705845709927
- Mean Citation Score: 414.360242
- Max Citation Score: 425.63605
- Similarity Product: 379.8484805343628

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test