PATENT CLAIM ANALYSIS

Application Number: 15766222
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "277000"]

Abstract:
The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Claim (Index 40):
The compound according to  claim 27  which is:\n 1-benzyl-N5-ethyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-2-oxo-N5-propyl-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-butyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-isopentyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(4-(methylamino)-4-oxobutyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n tert-butyl (3-(1-benzyl-5-(methylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxamido)propyl)carbamate; \n 1-benzyl-N3-methyl-2-oxo-N5-(3,3,3-trifluoropropyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-imidazol-5-yl)ethyl)-1-benzyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n methyl 4-(1-benzyl-5-(methylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxamido)butanoate; \n 1-benzyl-N3-methyl-2-oxo-N5-(2-(pyridin-2-yl)ethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(3-(1H-imidazol-2-yl)propyl)-1-benzyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-4-yl)ethyl)-1-benzyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-4-yl)ethyl)-N3-methyl-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-ethyl-N3-methyl-1-(3-methylbenzyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n (R)-N5-(2-(1H-pyrazol-4-yl)ethyl)-N3-methyl-2-oxo-1-(1-phenylethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n (R)-N5-ethyl-N3-methyl-2-oxo-1-(1-phenylethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-4-yl)ethyl)-1-(3-methoxybenzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-ethyl-1-(3-methoxybenzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-imidazol-4-yl)ethyl)-1-(3-(2-hydroxyethoxy)benzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-ethyl-1-(3-(2-hydroxyethoxy)benzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-4-yl)ethyl)-1-(3-(2-hydroxyethoxy)benzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-ethyl-1-(2-fluoro-3-methylbenzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-4-yl)ethyl)-1-(2-fluoro-3-methylbenzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-imidazol-4-yl)ethyl)-1-((1H-indol-4-yl)methyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-((1H-indol-4-yl)methyl)-N5-ethyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-((1H-indol-4-yl)methyl)-N5-(2-(1H-pyrazol-4-yl)ethyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3,N5-dimethyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-isobutyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-methoxypropyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-isopropyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-hydroxypropyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-hydroxypropyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-(dimethylamino)butyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-2-oxo-N5-(2-(pyridin-4-yl)ethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(3-(methylamino)-3-oxopropyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-cyanopropyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-cyanoethyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(3-aminopropyl)-1-benzyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-hydroxybutyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-2-oxo-N5-(2-(pyridin-3-yl)ethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-methoxyethyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-methoxypropyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-(3-cyanobenzyl)-N3,N5-dimethyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 4-(1-benzyl-5-(methylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxamido)butanoic acid; \n 1-benzyl-N3-methyl-N5-(2-(methylsulfonyl)ethyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-hydroxyethyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(3-(dimethylamino)propyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(3-(methylsulfonyl)propyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-imidazol-4-yl)ethyl)-1-(2-fluoro-3-methylbenzyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n N5-(2-(1H-pyrazol-5-yl)ethyl)-1-benzyl-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(1-methyl-1H-pyrazol-3-yl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(2-(1-methyl-1H-pyrazol-4- yl)ethyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(1-methyl-1H-pyrazol-4-yl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(2-(4-methyl-4H-1,2,4-triazol-3-yl)ethyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-N5-(2-(4-methylthiazol-5-yl)ethyl)-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N3-methyl-2-oxo-N5-(2-(thiazol-4-yl)ethyl)-1,2-dihydropyridine-3,5-dicarboxamide; \n 1-benzyl-N5-(2-(isoxazol-4-yl)ethyl)-N3-methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide; and \n 1-benzyl-N3-methyl-2-oxo-N5-(pyridazin-4-yl)-1,2-dihydropyridine-3,5-dicarboxamide; \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.125
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15762229', '15757199', '16091577', '14190477', '14977508']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7616779883994781
- 35 USC 102 Novelty (BERT): 0.6008129315422253
- Combined Prediction Score: 0.7455914827137528
- Mean Citation Score: 410.926672
- Max Citation Score: 523.60333
- Similarity Product: 448.1524904235935

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test