PATENT CLAIM ANALYSIS

Application Number: 15947741
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "455000"]

Abstract:
The present invention relates in pan to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.

Claim (Index 18):
A method for reprogramming a non-pluripotent cell, comprising:\n (a) providing a non-pluripotent cell; (b) culturing the non-pluripotent cell; (c) transfecting the non-pluripotent cell with one or more synthetic RNA molecules, wherein the one or more synthetic RNA molecules include at least one RNA molecule encoding one or more reprogramming factors and wherein the transfecting results in the cell expressing the one or more reprogramming factors; and (d) repeating step (c) at least twice during 5 consecutive days, wherein the amount of one or more synthetic RNA molecules transfected in one or more later transfections is greater than the amount transfected in one or more earlier transfections, to result in the non-pluripotent cell being reprogrammed, wherein steps (c) and (d) occur in the presence of a medium containing ingredients that support reprogramming of the non-pluripotent cell.

Metadata:
- Claim Count in Document: 55.0
- Percentile: 91.0
- Lexical Diversity: 1.55172
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15358818', '15605513', '15178190', '13465490', '14810123']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6558490624290827
- 35 USC 102 Novelty (BERT): 0.5480854456768172
- Combined Prediction Score: 0.6450727007538561
- Mean Citation Score: 379.825306
- Max Citation Score: 381.86386
- Similarity Product: 347.2641666932916

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test