PATENT CLAIM ANALYSIS

Application Number: 15861853
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "005900"]

Abstract:
The present system is directed in one embodiment to a method of administration of a therapeutic composition for treatment, prevention and/or mitigation of the frequency and/or severity of impaired awareness of hypoglycemia (IAH). The method includes administering one or more therapeutic agent(s) or composition(s) comprising insulin to the upper third of a patient's nasal cavity, thereby delivering the therapeutic composition directly to the patient's central nervous system for treatment, prevention and/or mitigation of the frequency and/or severity of IAH. In still another embodiment, the therapeutic composition comprises a non-zinc containing form of insulin.

Claim (Index 12):
A method for preventing, reducing the number, or mitigating the severity, of events comprising a steep drop in blood glucose levels in patients with impaired awareness of hypoglycemia, comprising:\n identifying a patient with a history of impaired awareness of hypoglycemia and therefore at risk for steep drops in blood glucose levels without self-recognition of hypoglycemic warning symptoms; providing at least one effective amount of a therapeutic compound comprising an insulin as a preventive and/or mitigating measure; administering the at least one effective amount of the therapeutic compound comprising an insulin to the upper one-third of the nasal cavity of the patient, thereby enabling the administered at least one effective amount of the therapeutic compound comprising an insulin to bypass the patient's blood-brain barrier; directly delivering the at least one effective amount of the therapeutic compound comprising an insulin to the patient's central nervous system (CNS); and preventing, reducing the frequency of, and/or mitigating the severity and/or length of, events involving a steep drop in glucose levels in the patient with impaired awareness of hypoglycemia.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 86.0
- Lexical Diversity: 1.92982
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14040915', '15340160', '14679667', '14202932', '12134385']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7396232499496584
- 35 USC 102 Novelty (BERT): 0.5299402629720333
- Combined Prediction Score: 0.7186549512518959
- Mean Citation Score: 303.49486
- Max Citation Score: 336.12085
- Similarity Product: 254.7695725330502

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test