PATENT CLAIM ANALYSIS

Application Number: 16020688
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "267000"]

Abstract:
The present invention provides, inter alia, compounds capable of inhibiting NF-κB. Pharmaceutical compositions containing and methods of using the compounds are also provided herein. Also provided are methods and kits for treating cancer and solid tumors in a subject, as well as methods and kits for inducing cancer cell death and apoptosis of a cancer cell, all utilizing the NF-κB inhibitors described herein.

Claim (Index 2):
The method according to  claim 1 ,\n wherein:\n X, Y, and Z are independently selected from the group consisting of oxygen and sulfur; \n R 1  is selected from the group consisting of \u2014H, \u2014F, \u2014Cl, \u2014OMe, and \u2014OEt; \n R 2  is selected from the group consisting of \u2014H, \u2014CH 3 , \u2014OH, \u2014OMe, \u2014OEt, -Me, -Et, -nPr, \u2014O-nPr, \u2014OEtnPr, \u2014OC 4 H 9 , \u2014OC 5 H 11 , \u2014OC 6 H 13 , \u2014OC 7 H 15 , \u2014O-isobutyl, \u2014O\u2014 isopentyl, \u2014OC n H 2n OMe, \u2014OC n H 2n OC m H 2m OMe, \u2014OC n H 2n OH, \u2014OC n H 2n OC m H 2m OH, \u2014OC n H 2n OEt, \u2014OC n H 2n OC m H 2m OEt, \u2014O\u2014C n H 2n COOH, \u2014O\u2014C n H 2n CONH2, \u2014O\u2014C n H 2n CONHMe, \n R 3  is selected from the group consisting of \u2014H, \u2014Cl, \u2014Br, \u2014F, and \u2014OMe; R 4  is selected from the group consisting of \u2014H and \u2014OMe; R 5  is selected from the group consisting of \u2014H, -Me, -Et, \u2014Pr, -iPr, -Ph, -iBu, and -nBu; and R 6  is selected from the group consisting of \u2014H and \u2014CH 3 , m is 2, 3, 4 or 5; n is 2, 3, 4, or 5; or a crystalline form, hydrate, or pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 94.0
- Lexical Diversity: 1.59091
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15393507', '12604970', '14032739', '13035640', '14088804']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8108762447520448
- 35 USC 102 Novelty (BERT): 0.5707065498876006
- Combined Prediction Score: 0.7868592752656004
- Mean Citation Score: 335.78576400000014
- Max Citation Score: 451.7303
- Similarity Product: 432.951167849201

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test