PATENT CLAIM ANALYSIS

Application Number: 15875192
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "061000"]

Abstract:
Provided are compositions related to HSD17B13 variants, including nucleic acid molecules and polypeptides related to variants of HSD17B13, and cells comprising those nucleic acid molecules and polypeptides. Also provided are methods related to HSD17B3 variants. Such methods include methods for detecting the presence of the HSD17B13 rs72613567 variant in a biological sample comprising genomic DNA, for detecting the presence or levels of any one of variant HSD17B13 Transcripts C, D, E, F, G, and H, and particularly D, in a biological sample comprising mRNA or cDNA, or for detecting the presence or levels of any one of variant HSD17B13 protein Isoforms C, D, E, F, G, or H, and particularly D, in a biological sample comprising protein. Also provided are methods for determining a subject's susceptibility to developing a liver disease or of diagnosing a subject with liver disease.

Claim (Index 1):
A nucleic acid molecule comprising: a) at least 15 contiguous nucleotides of an HSD17B13 gene, wherein the contiguous nucleotides are at least about 95% identical to a corresponding sequence in SEQ ID NO:2, and having a thymine at a position corresponding to position 12666 of SEQ ID NO:2; or b) a nucleotide sequence that encodes a polypeptide having an amino acid sequence that is at least about 95% identical to the amino acid sequence of HSD17B13 Isoform D (SEQ ID NO:42).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 2.6129
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12444903', '13974007', '12081101', '12339877', '11405322']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6176083185574809
- 35 USC 102 Novelty (BERT): 0.5079830245939955
- Combined Prediction Score: 0.6066457891611323
- Mean Citation Score: 273.25583
- Max Citation Score: 288.2544
- Similarity Product: 201.28481858997344

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test