PATENT CLAIM ANALYSIS

Application Number: 15885591
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "078300"]

Abstract:
Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo environments.

Claim (Index 2):
The composition of  claim 1 , wherein the hydrophobic moiety is a polymer selected from the group consisting of a polymer of: an acrylate, an acrylonitrile, a methacrylonitrile, vinyl acetate, vinylversatate, vinylpropionate, vinylformamide, vinylacetamide, vinylpyridine, vinylimidazole, an aminoalkylacrylate, an aminoalkylmethacrylate, an aminoalkyl(meth)acrylamide, a styrene, cellulose acetate phthalate, cellulose acetate succinate, and hydroxypropylmethylcellulose phthalate, and the polymers: poly(D,L lactide), poly(L-lactic acid), poly(D,L-lactide-co-glycolide), poly(glycolide), poly(hydroxybutyrate), poly(alkylcarbonate), a poly(orthoester), a polyester, poly(hydroxyvaleric acid), polydioxanone, poly(ethylene terephthalate), poly(malic acid), poly(tartronic acid), a polyanhydride, a polyphosphazene, a poly(amino acid),an amino acid copolymer, poly(ethylene-vinyl acetate), a poly(ethylene-vinyl acetate) (\u201cEVA\u201d) copolymer, silicone rubber, polyethylene, polypropylene, a polydiene, a hydrogenated form of a polydiene, a maleic anhydride copolymer of vinyl-methylether and other vinyl ethers, a polyamide (nylon 6,6), polyurethane, a poly(ester urethane), a poly(ether urethane), poly(ester-urea), polycaproic acid, polymethylbenzylate, poly(caprolactone), poly(valerolactone), a copolymer of poly(caprolactone) and poly(lactic acid), or\n is vitamin E, vitamin K, vitamin A, beta carotene, astaxanthin, trans- and cis-retinal, retinoic acid, retinyl acetate, retinyl palmitate, cholecalciferol, calcitriol, hydroxycholecalciferol, ergocalciferol, \u03b1-tocopherol, \u03b1-tocopherol acetate, \u03b1-tocopherol nicotinate, or estradiol, and/or \n wherein, in said amphiphilic stabilizer, a hydrophilic polymeric block is coupled to a hydrophobic polymeric block, wherein: \n the hydrophobic block is selected from the group consisting of a polymer of: an acrylate, an acrylonitrile; methacrylonitrile, vinyl acetate, vinylversatate, vinylpropionate, vinylformamide, vinylacetamide, vinylpyridine, vinylimidazole, an aminoalkylacrylate, an aminoalkylmethacrylate, an aminoalkyl(meth)acrylamide, styrene, cellulose acetate phthalate, cellulose acetate succinate, hydroxypropylmethylcellulose phthalate, \n and the polymers: poly(D,L lactide), poly(L-lactic acid), poly (D,L-lactide-co-glycolide), poly(glycolide), poly(hydroxybutyrate), poly(alkylcarbonate), a poly(orthoester), a polyester, poly(hydroxyvaleric acid), polydioxanone, poly(ethylene terephthalate), poly(malic acid), poly(tartronic acid), a polyanhydride, a polyphosphazene, a poly(amino acid), an amino acid copolymer, poly(ethylene-vinyl acetate), a poly(ethylene-vinyl acetate) (\u201cEVA\u201d) copolymer, silicone rubber, polyethylene, polypropylene, a polydiene, a hydrogenated form of polydiene, a maleic anhydride copolymer of vinyl methylether and other vinyl ethers, a polyamide (nylon 6,6), polyurethane, a poly(ester urethane), a poly(ether urethane), poly(ester-urea), poly(caprolactone), poly(valerolactone), and a copolymer of poly(caprolactone) and poly(lactic acid); and \n the hydrophilic block is selected from the group consisting of a polymer of a carboxylic acid, a polyoxyethylene, a polyacrylamide; a copolymer of acrylamide with dimethylaminoethylmethacrylate, diallyldimethylammonium chloride, vinylbenzylthrimethylammonium chloride, acrylic acid, methacrylic acid, 2-acrylamido-2-methylpropane sulfonic acid, and styrene sulfonate; polyvinyl pyrrolidone, starch, a starch derivative, dextran, a dextran derivative, a polypeptide, poly hyaluronic acid, an alginic acid, a polylactide, a polyethyleneimine, a polyionene, a polyacrylic acid, a polyiminocarboxylate, and gelatin.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.14286
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10101093', '13820351', '10984679', '10416980', '14575517']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7567760378949843
- 35 USC 102 Novelty (BERT): 0.4843024161634973
- Combined Prediction Score: 0.7295286757218356
- Mean Citation Score: 227.12185800000003
- Max Citation Score: 229.39345
- Similarity Product: 184.72085057564675

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test