PATENT CLAIM ANALYSIS

Application Number: 16283525
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-08
Patent Classification: ["514", "014100"]

Abstract:
The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation. More specifically, the present invention relates to a modified, recombinant Factor VIII (FVIII) with extended half-life and reduced ligand-binding properties.

Claim (Index 1):
A method of treating a hemorrhagic defect in a mammal comprising the step of administering a PSA modified FVIII, to the mammal in an amount effective to reduce or eliminate one or more symptoms of said hemorrhagic defect.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 99.0
- Lexical Diversity: 1.41304
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12843542', '15249657', '12684482', '12684536', '12184567']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7533884337169114
- 35 USC 102 Novelty (BERT): 0.5090663493818465
- Combined Prediction Score: 0.728956225283405
- Mean Citation Score: 234.63339
- Max Citation Score: 248.89162
- Similarity Product: 154.07425723351716

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test