PATENT CLAIM ANALYSIS

Application Number: 16078054
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "217100"]

Abstract:
Provided are a urea compound represented by general formula (I), a pharmaceutically acceptable salt thereof, a preparation method therefor, and use thereof as an FLT3 tyrosine protein kinase inhibitor, particularly in the prevention and/or treating of cancer.

Claim (Index 11):
The compound of general formula (I) or the pharmaceutically acceptable salt, solvate or prodrug thereof according to  claim 1 ,\n wherein, in the absence of R 1 , B is selected from the group consisting of hydrogen, halogen, C 1 -C 6  alkyl, C 1 -C 6  haloalkyl; in the presence of R 1 , B is identical or different and each is independently selected from \u2014O\u2014 or \u2014NR 4 \u2014, preferably \u2014O\u2014; and R 1  is identical or different and is each independently selected from \u2014R u N(R y )(R z ), wherein R u  is selected from C 1 -C 6  alkylene; R y  and R z  are each independently selected from the group consisting of hydrogen, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, C 1 -C 6  haloalkyl, C 1 -C 6  haloalkoxy, C 3 -C 7  cycloalkyl; or, R y  and R z  together with the nitrogen atom attached to them form a 5- to 7-membered heterocyclyl group or a 5- to 7-membered heteroaryl group, preferably morpholinyl, piperidinyl, piperazinyl, azepanyl, pyridyl, pyrimidinyl, and the 5- to 7-membered heterocyclyl group or a 5- to 7-membered heteroaryl group is optionally further substituted by one or more groups selected from the group consisting of halogen, C 1 -C 6  alkyl, and C 1 -C 6  haloalkyl; R 4  is as defined in  claim 1 .

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.15789
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14297790', '13389146', '10939324', '11201823', '12105408']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.827399578466244
- 35 USC 102 Novelty (BERT): 0.5256280968895454
- Combined Prediction Score: 0.7972224303085742
- Mean Citation Score: 335.0989120000001
- Max Citation Score: 349.75607
- Similarity Product: 254.7321320051741

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test