PATENT CLAIM ANALYSIS

Application Number: 16165602
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "044000"]

Abstract:
Androgen receptor-based vaccines for eliciting an immune reaction in vivo against cells expressing androgen receptor are disclosed. The vaccines are useful in the treatment of prostate cancer. Also disclosed are methods for inducing immune reaction to androgen receptor or treating prostate cancer in a mammal, using the vaccines and pharmaceutical compositions comprising the vaccines.

Claim (Index 3):
The DNA vaccine of  claim 1 , wherein the plasmid vector comprises\n (a) a polynucleotide operatively linked to a CMV promoter wherein the polynucleotide encodes a member selected from (i) a mammalian androgen receptor, (ii) a fragment of the androgen receptor that comprises a ligand-binding domain, (iii) a fragment of the ligand-binding domain defined by SEQ ID NO:9, (iv) a fragment of the ligand-binding domain defined by SEQ ID NO:10, (v) a fragment of the ligand-binding domain defined by SEQ ID NO:11, and (vi) a fragment of the ligand-binding domain defined by SEQ ID NO:12; (b) a CMV intron A operatively linked to the polynucleotide for enhancing expression of the polynucleotide; and optionally (c) at least one copy of an immunostimulatory fragment comprising 5\u2032-GTCGTT-3\u2032.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.48718
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13031396', '13968854', '14614137', '11848607', '15238016']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8623549731499721
- 35 USC 102 Novelty (BERT): 0.716308804880108
- Combined Prediction Score: 0.8477503563229857
- Mean Citation Score: 766.5322600000003
- Max Citation Score: 783.5026
- Similarity Product: 758.5200373459578

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test