PATENT CLAIM ANALYSIS

Application Number: 16298521
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "317100"]

Abstract:
Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (IA) are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having IA.

Claim (Index 7):
A method of monitoring efficacy of a treatment for invasive aspergillosis (IA) in a subject, the method comprising:\n determining a first level of one, two, three, or more volatile organic compounds (VOCs) produced by the  Aspergillus  species in a sample comprising breath from the subject or headspace from a culture suspected of comprising  Aspergillus  isolated from the subject, wherein the VOCs are selected from the group consisting of camphene, \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, trans-geranylacetone, elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, 1,5,9-trimethyl cyclododecatriene, 9-decene-2-one and beta-sesquiphellandrene, in the subject; administering a treatment for IA to the subject; determining a second level of the VOCs in a sample obtained after administration of the treatment to the subject; and comparing the first and second levels of VOCs, wherein a decrease in the VOCs indicates that the treatment has been effective in treating the IA in the subject, and an increase or no change indicates that the treatment has not been effective in treating the IA in the subject.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.27778
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316062', '14426678', '15023640', '14628125', '13261101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5986792279379023
- 35 USC 102 Novelty (BERT): 0.6651027772228992
- Combined Prediction Score: 0.605321582866402
- Mean Citation Score: 408.262416
- Max Citation Score: 777.9191
- Similarity Product: 620.3995814261792

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test