PATENT CLAIM ANALYSIS

Application Number: 16033395
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-04
Patent Classification: ["546", "119000"]

Abstract:
The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Claim (Index 2):
The compound or pharmaceutically acceptable salt thereof according to  claim 1  of formula (Ib): wherein:\n R1 is selected from the group consisting of hydrogen, linear or branched C 1 -C 5  alkyl, and saturated monocyclic C 3 -C 5  cycloalkyl; \n R2 is selected from the group consisting of linear or branched C 1 -C 8  alkyl, saturated monocyclic C 3 -C 8  cycloalkyl, oxetanyl, tetrahydrofuranyl, and tetrahydropyranyl; all of which can be optionally substituted one or more times with one or more substituents selected from the group consisting of methyl, fluorine, hydroxy, cyano or methoxy; \n R3 is methyl substituted with phenyl, pyridonyl or pyridinyl all of which can be optionally substituted one or more times with one or more substituents selected from the group consisting of halogen, C 1 -C 3  alkyl and methoxy; or \n R3 is methyl substituted with a 5-membered heteroaryl which is optionally substituted with one or more substituents selected from C 1 -C 3  alkyl and C 1 -C 3  fluoroalkyl; or \n R3 is ethyl substituted with phenyl, pyridonyl or pyridinyl all of which can be optionally substituted one or more times with one or more substituents selected from the group consisting of halogen, C 1 -C 3  alkyl and methoxy; or \n R3 is ethyl substituted with a 5-membered heteroaryl which is optionally substituted with one or more substituents selected from C 1 -C 3  alkyl and C 1 -C 3  fluoroalkyl; and \n R4 is phenyl, pyridinyl or pyridonyl all of which can be optionally substituted one or more times with one or more substituents selected from the group consisting of halogen, C 1 -C 3  alkyl and C 1 -C 3  alkoxy; or \n R4 is a 5-membered heteroaryl which is optionally substituted with one or more substituents selected from C 1 -C 3  alkyl and C 1 -C 3  fluoroalkyl.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 95.0
- Lexical Diversity: 1.125
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15637920', '15849798', '16340429', '12303618', '14671531']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.848170062274921
- 35 USC 102 Novelty (BERT): 0.6078556130485118
- Combined Prediction Score: 0.82413861735228
- Mean Citation Score: 413.943516
- Max Citation Score: 574.4137
- Similarity Product: 489.3991017954111

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test