PATENT CLAIM ANALYSIS

Application Number: 15863578
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["536", "024500"]

Abstract:
The present invention relates to RNAi molecules, and compositions thereof, comprising a 2′ internucleoside linkage connecting the nucleotide at position 1 and the nucleotide at position 2 at the 5′ end of the antisense strand. Specifically, the invention relates to single- and double-stranded short interfering nucleic acid (siNA) molecules that are capable of mediating RNA interference comprising 5′ modified nucleotides that comprise, among other potential modifications, a 2′ internucleoside linkage. The invention further relates to 5′ modified nucleotides used as reagents to generate the RNAi molecules of the invention and methods of using the disclosed RNAi molecules.

Claim (Index 58):
The siNA molecule of  claim 47 , which further comprises a conjugate.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 86.0
- Lexical Diversity: 1.78333
- Patent Class: 536.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14769361', '15035950', '15684902', '14514112', '14339067']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.669786905711113
- 35 USC 102 Novelty (BERT): 0.6010305958745035
- Combined Prediction Score: 0.662911274727452
- Mean Citation Score: 471.127696
- Max Citation Score: 686.4133
- Similarity Product: 445.3555562207759

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test