PATENT CLAIM ANALYSIS

Application Number: 15753160
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "254100"]

Abstract:
The invention relates to salinomycin derivatives such as compounds having the structure of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a therapeutically effective amount of compounds of formula (I), and the use of compounds of formula (I) for treating or inhibiting progression of cancer. The cancer is selected from the group consisting of breast cancer, pancreatic cancer, and prostate cancer.

Claim (Index 1):
A compound having the structure of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: X is R is selected from the group consisting of H, C 1 -C 6  alkyl, C 2 -C 6  alkenyl, C 2 -C 6  alkynyl, C 1 -C 6  heteroalkyl, C 3 -C 7  carbocyclyl, 5-10 membered heterocyclyl, C 6-10  aryl, and 5-10 membered heteroaryl; n is an integer from 0 to 6; Y is selected from the group consisting of \u2014NR 1 C(O), \u2014C(O)NR 1 \u2014, \u2014OC(O)\u2014, C(O)O\u2014, \u2014CR 1 (COOR 2 )\u2014CR 3 \u2550CR 4 \u2014, and \u2014CR 1 \u2550CR 2 \u2014; m is an integer from 0 to 6; Z is \u2014CR 1 \u2550CR 2 \u2014, \u2014CR 1 (COOR 2 )\u2014CR 3 \u2550CR 4 , or absent; G is selected from the group consisting of C 1 -C 6  alkyl, C 2 -C 6  alkenyl, C 2 -C 6  alkynyl, C 1 -C 6  heteroalkyl, C 3 -C 7  carbocyclyl, 5-10 membered heterocyclyl, C 6-10  aryl, and 5-10 membered heteroaryl, each optionally substituted with 1-3 substituents selected from the group consisting of halogen, C 1-4  alkyl, halogenC 1-4  alkyl, \u2014OR 1 , \u2014CN, \u2014NO 2 , \u2014N 1 R 2 , \u2014C(O)NR 1 R 2 , and \u2014NR 1 C(O)R 5 ; and each of R 1 , R 2 , R 3 , R 4 , and R 5  are independently selected from \u2014H, \u2014CN, \u2014NO 2 , \u2014NH 2 , \u2014OH, C 1-4  alkyl, halogenC 1-4  alkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 3-7  cycloalkyl, 3-8 membered heterocyclyl, C 6-10 aryl, and 5-10 membered heteroaryl.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 88.0
- Lexical Diversity: 1.65217
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14112581', '14836326', '14146671', '14112597', '15323081']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7659065972468896
- 35 USC 102 Novelty (BERT): 0.505756750871862
- Combined Prediction Score: 0.7398916126093869
- Mean Citation Score: 270.717512
- Max Citation Score: 273.77585
- Similarity Product: 223.90893161920607

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test