PATENT CLAIM ANALYSIS

Application Number: 16264097
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["548", "469000"]

Abstract:
The present invention relates to indole compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders.

Claim (Index 19):
A compound of formula II, III, IV, V or IV: or a pharmaceutically acceptable salt thereof, wherein: R 1  is R 2  is each R A  is independently \u2014R, halogen, -haloalkyl, -hydroxyalkyl, \u2014OR, \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014C(O)R, \u2014CO 2 R, \u2014C(O)N(R) 2 , \u2014NRC(O)R, \u2014NRC(O)N(R) 2 , \u2014NRSO 2 R, or \u2014N(R) 2 ; each R is independently hydrogen, C 1-6  aliphatic, C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; or two R groups on the same atom are taken together with the atom to which they are attached to form a C 3-10  aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; provided that, if the compound is of formula II, R 1  is not and provided that, if the compound is of formula III, R 2  is not

Metadata:
- Claim Count in Document: 8.0
- Percentile: 99.0
- Lexical Diversity: 1.16667
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15370645', '14969328', '14814659', '14730351', '15626138']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7594041932620746
- 35 USC 102 Novelty (BERT): 0.5125075352697454
- Combined Prediction Score: 0.7347145274628417
- Mean Citation Score: 266.416144
- Max Citation Score: 289.2787
- Similarity Product: 201.9793504964113

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test