PATENT CLAIM ANALYSIS

Application Number: 15909264
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["073", "061520"]

Abstract:
The present disclosure relates to methodologies, systems and apparatus for controlling pressure in a CO 2 -based chromatography system. A first CO 2  pump operates in constant flow mode and delivers CO 2  to a chromatography column, and liquid modifier is introduced to the chromatography column according to a gradient. A second CO 2  pump is disposed downstream of the column and operates in constant pressure mode to introduce CO 2  into a flow stream at an output of the column. Liquid modifier is also introduced into the flow stream at the output of the column according to a reverse gradient compared to the gradient entering the chromatography column.

Claim (Index 1):
A CO 2 -based chromatography system comprising:\n a first CO 2  pump disposed to deliver CO 2  to a chromatography column; a first liquid modifier pump disposed to deliver a liquid modifier to the chromatography column; a second CO 2  pump located downstream of the column and disposed to operate independently of the first CO 2  pump to introduce CO 2  into a flow stream at an output of the column, the second CO 2  pump operating in constant pressure mode in order to maintain a target pressure; and a second liquid modifier pump located downstream of the column and disposed to operate independently of the first liquid modifier pump to introduce liquid modifier into the flow stream at the output of the column, the second liquid modifier pump further disposed to deliver liquid modifier according to a reverse gradient compared to a gradient entering the column via the first liquid modifier pump.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 90.0
- Lexical Diversity: 2.21154
- Patent Class: 73.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15909275', '14782476', '14125957', '12280585', '14432313']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7022127811389123
- 35 USC 102 Novelty (BERT): 0.5029339996411043
- Combined Prediction Score: 0.6822849029891315
- Mean Citation Score: 240.260052
- Max Citation Score: 294.65903
- Similarity Product: 245.18814225898265

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test