PATENT CLAIM ANALYSIS

Application Number: 16403288
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-08
Patent Classification: ["514", "237500"]

Abstract:
Improved methods of treating multiple sclerosis and/or psoriasis using prodrugs of methyl hydrogen fumarate are disclosed. The methods comprise administering certain prodrugs of methyl hydrogen fumarate. The methods are able to achieve high blood plasma concentrations of the active metabolite, methyl hydrogen fumarate, without causing significant gastrointestinal irritation. New prodrugs of methyl hydrogen fumarate are also disclosed.

Claim (Index 27):
The oral pharmaceutical formulation of  claim 16 , wherein said compound exhibits the following characteristics or effect:\n exhibits a human in vivo metabolism to MHF over 24 hours sufficient to achieve a ratio of AUC MMF 0-24 : AUC prodrug 0-24  of at least 19:1.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 100.0
- Lexical Diversity: 1.65789
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13973456', '15395977', '13761864', '12544133', '13274284']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7789465675717527
- 35 USC 102 Novelty (BERT): 0.5096430053483978
- Combined Prediction Score: 0.7520162113494173
- Mean Citation Score: 271.159026
- Max Citation Score: 295.05405
- Similarity Product: 236.1805772129953

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test