PATENT CLAIM ANALYSIS

Application Number: 16319951
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["544", "277000"]

Abstract:
There are provided substituted purine and 3-deazapurine analogues, which modulate the activity of Choline Kinase (ChoK). The compounds of this invention are therefore useful in treating diseases caused by an altered choline metabolism, such as cancer, cell proliferative disorders, infectious diseases of different origin, immune-related disorders and neurodegenerative disorders. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.

Claim (Index 3):
A compound or pharmaceutically acceptable salt according to  claim 2 , wherein:\n X is CH or nitrogen; A is a 6-membered cycloalkyl or a 6-membered nitrogen-containing heterocyclyl; R1 is linked: either 1) to any A ring carbon, in which case R1 is \u2014CONR4R5, \u2014NR4COR5, \u2014NR4CONR4R5, \u2014NR4CSNR4R5, or \u2014NR4SO 2 R6, or 2) to the A ring nitrogen, in which case R1 is \u2014COR5, \u2014CONR4R5, \u2014CSNR4R5 or \u2014SO 2 R6;\n wherein: \n R4 and R5 are independently hydrogen or an optionally substituted group selected from (C 1 -C 6 )alkyl, aryl and heteroaryl, and; \n R6 is an optionally substituted group selected from (C 1 -C 6 )alkyl, aryl and heteroaryl; \n n is 0, 1 or 2; R2 is an optionally substituted (C 1 -C 6 )alkyl; provided that\n when n is 2 the R2 groups are not necessarily the same; \n wherein the R1 and R2 groups can be linked to the same ring carbon; \n R3 is halogen, cyano or an optionally substituted group selected from polyfluorinated(C 1 -C 6 )alkyl, (C 2 -C 6 )alkynyl, aryl, heteroaryl, \u2014OR6 and \u2014CONR4R5, wherein R4, R5 and R6 are as defined above.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 99.0
- Lexical Diversity: 1.52632
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12678806', '13377854', '14874513', '15335619', '13780557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7936381874978958
- 35 USC 102 Novelty (BERT): 0.5052014150211619
- Combined Prediction Score: 0.7647945102502224
- Mean Citation Score: 270.152288
- Max Citation Score: 281.84406
- Similarity Product: 209.8352325195408

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test