PATENT CLAIM ANALYSIS

Application Number: 15957019
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["424", "085200"]

Abstract:
Methods are provided for treating ocular surface inflammation and/or uveitis in a subject. The methods can include selecting a subject with uveitis and/or ocular surface disease. The methods can then include administering to the subject a therapeutically effective amount of an interleukin 24 (IL-24) polypeptide or nucleic acid encoding the IL-24 polypeptide. In some examples, the administered IL-24 polypeptide suppresses production of effector cytokines by Th17 cells. A pharmaceutical composition is further provided here that includes an IL-24 polypeptide or nucleic acid encoding the polypeptide. In some examples, the IL-24 polypeptide is a variant of IL-24 or an Fc fusion protein that includes IL-24. The pharmaceutical composition can be used in any of the methods provided herein to treat ocular surface inflammation and/or uveitis.

Claim (Index 13):
The method of  claim 1 , comprising selecting the subject with the ocular surface disease, and wherein the subject has dry eye, non-dry eye lid disease, non-dry eye conjunctivitis, and/or keratitis.

Metadata:
- Claim Count in Document: 63.0
- Percentile: 91.0
- Lexical Diversity: 1.95652
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13392811', '14679497', '14071559', '12685510', '14821567']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6753844122201694
- 35 USC 102 Novelty (BERT): 0.5274785874389951
- Combined Prediction Score: 0.660593829742052
- Mean Citation Score: 308.7173200000001
- Max Citation Score: 312.58112
- Similarity Product: 199.0820793347168

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test