PATENT CLAIM ANALYSIS

Application Number: 15744510
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "222800"]

Abstract:
The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N′, C′, A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.

Claim (Index 1):
A compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: wherein:\n X represents O or S; \n the moiety \n represents \u2014N(D)-C(A)\u2550C(E)- or \u2014N\u2550C(A)-C(R 1 )(E)-; D represents H or C 1 -C 6  alkyl, wherein the alkyl group of D is unsubstituted or is substituted with 1, 2 or 3 substituents selected from halogen, OH, and C 1 -C 2  alkoxy; and wherein the alkyl group of D is uninterrupted or is interrupted by \u2014O\u2014, \u2014C(O)\u2014, \u2014OC(O)\u2014 or \u2014C(O)O\u2014; R 1  is H or C 1 -C 2  alkyl; one group selected from A and E represents a group Q1, and the other group selected from A and E represents a group Q2; Q1 represents\n (i) H or C 1 -C 8  alkyl, wherein the alkyl group of Q1 is unsubstituted or is substituted with 1, 2 or 3 substituents selected from halogen, OH, and C 1 -C 2  alkoxy; and wherein the alkyl group of Q1 is uninterrupted or is interrupted by \u2014O\u2014, \u2014C(O)\u2014, \u2014OC(O)\u2014 or \u2014C(O)O\u2014; \n or\n (ii) an alkylene group which is bonded to an atom of group Q2 to form a C 5 -C 6  carbocyclyl or 5- to 6-membered heterocyclyl moiety, wherein the carbocylyl or heterocyclyl moiety is saturated or partially unsaturated; and wherein the carbocyclyl or heterocyclyl moiety is unsubstituted or is substituted with 1, 2 or 3 substituents selected from halogen, C 1 -C 4  alkoxy, unsubstituted C 1 -C 4  alkyl and C 1 -C 4  alkyl substituted with 1, 2 or 3 substituents independently selected from halogen and \u2014OH; \n Q2 represents a group -L-T or -T, wherein\n L is selected from C 1 -C 12  alkylene and C 2 -C 12  alkenylene, wherein the alkylene or alkenylene group of L is unsubstituted or is substituted with 1, 2 or 3 groups selected from halogen, C 1 -C 4  alkoxy and \u2014OH; and \n wherein the alkylene or alkenylene group of L may optionally terminate in and/or be interrupted by a heteromoiety selected from \u2014O\u2014, \u2014S\u2014, \u2014C(O)\u2014, \u2014OC(O)\u2014, \u2014C(O)O\u2014, \u2014NR 2 \u2014, \u2014NR 2 C(O)\u2014, and \u2014C(O)NR 2 \u2014; and \n when Q2 is -L-T, then T is H, aryl, heteroaryl, cycloalkyl or heterocyclyl, and when Q2 is -T, then T is aryl, heteroaryl, cycloalkyl or heterocyclyl, wherein the aryl, heteroaryl, cycloalkyl or heterocyclyl group of T is unsubstituted or is substituted by 1, 2 or 3 groups V; \n each group V is independently selected from C 1 -C 6  alkoxy, unsubstituted C 1 -C 10  alkyl, C 1 -C 10  alkyl which is substituted with 1, 2 or 3 groups selected from halogen and C 1 -C 3  alkoxy, C 2 -C 6  alkenyl, C 2 -C 6  alkynyl, C 3 -C 6  cycloalkyl, halogen, aryl, (C 1 -C 6  alkyl)-aryl, aryloxy, aryloxy-(C 1 -C 6  alkyl), \u2014CN, NO 2 , \u2014(C 1 -C 6  alkyl)-C(O)O(C 1 -C 6  alkyl) and \u2014C(O)O(C 1 -C 6  alkyl); and R 2  is H or C 1 -C 2  alkyl.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.65
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12989410', '14625532', '12601284', '11914516', '12515354']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7413183613324029
- 35 USC 102 Novelty (BERT): 0.5199453160749961
- Combined Prediction Score: 0.7191810568066622
- Mean Citation Score: 288.72395399999994
- Max Citation Score: 300.37643
- Similarity Product: 212.1035993971849

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test