PATENT CLAIM ANALYSIS

Application Number: 16127772
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["514", "242000"]

Abstract:
The present invention relates to compounds capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds, and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Claim (Index 40):
The method of  claim 39 , wherein the disease is selected from Noonan Syndrome, Leopard Syndrome, Crouzon Syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrate, Apert syndrome, Pfeiffer syndrome, Muenke syndrome, Saethre-Chotzen-like syndrome, achondroplasia, SADDAN (severe achondroplasia with developmental delay and acanthosis nigricans), thanatophoric dysplasia type I, thanatophoric dysplasia type II, hypochondroplasia, Kallmann syndrome, myeloproliferative syndromes, juvenile myelomonocytic leukemias, multiple myeloma, 8P11 myeloproliferative syndrome (EMS), pancreatic adenocarcinoma, prostate cancer, astrocytoma, transitional cell carcinoma of bladder, thyroid carcinoma, cervical carcinoma, colorectal cancer, peripheral T cell lymphoma, seminomas, neuroblastoma, melanoma, acute myeloid leukemia, chronic myeologenous leukemia, breast cancer, esophageal cancer, lung cancer, colon cancer, head cancer, squamous-cell carcinoma of the head and neck, gastric carcinoma, anaplastic large-cell lymphoma and glioblastoma.

Metadata:
- Claim Count in Document: 128.0
- Percentile: 97.0
- Lexical Diversity: 1.61111
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14554263', '14155134', '15358371', '14554306', '15398907']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7525496630239774
- 35 USC 102 Novelty (BERT): 0.5308426468978142
- Combined Prediction Score: 0.7303789614113612
- Mean Citation Score: 305.715376
- Max Citation Score: 310.1815200000001
- Similarity Product: 184.324451094432

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test