PATENT CLAIM ANALYSIS

Application Number: 16206611
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["546", "152000"]

Abstract:
Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Claim (Index 1):
A method of treating cancer in a patient in need thereof, the method comprising administering to the patient a therapeutically effective amount of a compound, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of a tautomer thereof, wherein the compound has formula (I) or formula (II): wherein R 1 , R 2 , and R 3  are each independently hydrogen, halogen, N 3 , \u2014NHC\u2550(O)NHNH 2 , \u2014CN, \u2014CF 3 , \u2014CCl 3 , \u2014CBr 3 , \u2014CI 3 , \u2014NR 9 R 10 , \u2014C(O)R 11 , \u2014C(O)NR 9 R 10 , \u2014NR 12 C(O)R 11 , \u2014S(O) n R 13 , \u2014S(O) n NR 9 R 10 , \u2014NR 12 S(O) n R 13 , \u2014NO 2 , \u2014OR 14 , \u2014SR 14 , \u2014NR 15 , \u2014OCOR 16 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; L is a bond, \u2014C(O)\u2014NH\u2014, \u2014NH\u2014C(O)\u2014, \u2014C(O)\u2014, \u2014C(O)\u2014O\u2014, \u2014NH\u2014, \u2014O\u2014, \u2014S\u2014, \u2014S(O)\u2014, \u2014S(O) 2 \u2014, \u2014NH\u2014S(O)\u2014, \u2014NH\u2014S(O) 2 \u2014, \u2014CH 2 N(C(O)OH)\u2014, \u2014CH 2 \u2014N(CH(O))\u2014, \u2014CH 2 \u2014N(SO 2 )\u2014, \u2014CH 2 NH\u2014, \u2014CH 2 C(O)NH\u2014, \u2014CH 2 NHC(O)\u2014, \u2014CH 2 NHS(O)\u2014, \u2014CH 2 NHS(O) 2 \u2014, substituted or unsubstituted alkylene, substituted or unsubstituted heteroalkylene, substituted or unsubstituted cycloalkylene, substituted or unsubstituted heterocycloalkylene, substituted or unsubstituted arylene, or substituted or unsubstituted heteroarylene; X is hydrogen, halogen, \u2014N 3 , \u2014NHC\u2550(O)NHNH 2 , \u2014CN, \u2014CF 3 , \u2014CCl 3 , \u2014CBr 3 , \u2014CI 3 , \u2014NR 9 R 10 , \u2014C(O)R 11 , \u2014C(O)NR 9 R 10 , \u2014NR 12 C(O)R 11 , \u2014S(O) n R 13 , \u2014S(O) n NR 9 R 10 , \u2014NR 12 S(O) n R 13 , \u2014NO 2 , \u2014OR 14 , \u2014SR 14 , \u2014NR 15 , \u2014OCOR 16 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; R 9 , R 10 R 11 , R 12 , R 13 , R 14 , R 15 , and R 16 , are independently hydrogen, halogen, \u2014CN, \u2014CF 3 , \u2014CCl 3 , \u2014CBr 3 , \u2014CI 3 , \u2014OH, \u2014NH 2 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and n is 1 to 4.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 98.0
- Lexical Diversity: 1.07692
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15866268', '15428021', '15778213', '14670088', '15614278']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7720854502376338
- 35 USC 102 Novelty (BERT): 0.5763100093552785
- Combined Prediction Score: 0.7525079061493982
- Mean Citation Score: 389.158492
- Max Citation Score: 499.48798
- Similarity Product: 383.3559147571611

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test