PATENT CLAIM ANALYSIS

Application Number: 15981142
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "185100"]

Abstract:
The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity.

Claim (Index 6):
The CAR of  claim 1 , wherein the extracellular antigen-binding domain comprises a light chain variable region comprising amino acids 1-107 of SEQ ID NO:5 or amino acids 1-107 of SEQ ID NO:3.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 93.0
- Lexical Diversity: 1.24444
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15368278', '15105082', '15511973', '15866222', '15613800']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7876139117395108
- 35 USC 102 Novelty (BERT): 0.6795386179051786
- Combined Prediction Score: 0.7768063823560776
- Mean Citation Score: 585.336438
- Max Citation Score: 831.91907
- Similarity Product: 654.8632656184817

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test