PATENT CLAIM ANALYSIS

Application Number: 16061880
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["562", "506000"]

Abstract:
Disclosed is a new method for synthesizing 2-fluorocyclopropanecarboxylic acid comprising: 1) performing reaction of 1,1-dichloro-1-fluoroethane with thiophenol in the presence of an alkali, to produce a phenyl sulfide intermediate; 2) performing oxidation reaction of the phenyl sulfide intermediate with Oxone; 3) performing elimination reaction of the product of Step 2) in the presence of an alkali, to obtain 1-fluoro-1-benzenesulfonyl ethylene; 4) performing addition reaction of the 1-fluoro-benzenesulfonyl ethylene with ethyl diazoacetate in the presence of a catalyst, to obtain a cyclopropane intermediate; 5) performing elimination reaction of the cyclopropane intermediate in the presence of an alkali before acidification, to obtain 2-fluorocyclopropanecarboxylic acid. Herein, the synthetic route is short, used materials are bulk commodities, and raw materials are inexpensive and readily available. The process can be safely scaled up by replacing commonly used mCPBA reagents with Oxone. Further, reaction yield is improved, production cost is greatly reduced, and operation is simplified.

Claim (Index 10):
The new method for synthesizing 2-fluorocyclopropanecarboxylic acid of  claim 9 , wherein, in the step 5), an acid for the acidification is at least one selected from hydrochloric acid, sulfuric acid, nitric acid and perchloric acid.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 94.0
- Lexical Diversity: 2.01149
- Patent Class: 562.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13579045', '10541204', '15741020', '14395368', '15532957']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6582128448680907
- 35 USC 102 Novelty (BERT): 0.4930082475153918
- Combined Prediction Score: 0.6416923851328209
- Mean Citation Score: 153.89072
- Max Citation Score: 162.33441000000005
- Similarity Product: 113.01763444148364

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test