PATENT CLAIM ANALYSIS

Application Number: 16221201
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "210180"]

Abstract:
This invention is a benzothiophene estrogen receptor modulator or its pharmaceutically acceptable salt or a pharmaceutically acceptable composition thereof to treat an estrogen-related medical disorder.

Claim (Index 1):
A method of treating an estrogen-related disorder comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I or Formula III or a pharmaceutically acceptable salt thereof; wherein the compound of Formula I or Formula III is selected from: wherein A is: Y is m is 0, 1, or 2; n is 1, 2, or 3; o is 0, 1, 2, 3, 4, or 5; Z is selected from \u2014O\u2014, \u2014C(R 3 ) 2 \u2014, \u2014CHR 3 \u2014, \u2014CH 2 \u2014, \u2014CHF\u2014, \u2014CF 2 \u2014, and \u2014S\u2014; Z A  and Z B  are independently selected from \u2014O\u2014, \u2014C(R 3 ) 2 \u2014, \u2014CHR 3 \u2014, \u2014CH 2 \u2014, \u2014CHF\u2014, \u2014CF 2 \u2014, and \u2014S\u2014; each R 1  is independently selected from C 1 -C 3 alkyl, halogen, and C 1 -C 3 haloalkyl; R 2  is selected from:\n a. 4-6 membered heterocycle optionally substituted with one, two, or three groups independently selected from R 4 ; \n b. \u2014NH 2 , \u2014NH(C 1 -C 3 alkyl or C 2 -C 3 haloalkyl), and \u2014N((independently)C 1 -C 3 alkyl or C 2 -C 3 haloalkyl) 2 ; \n c. monocyclic 7-8 membered heterocycle optionally substituted with one, two, or three groups independently selected from R 4 ; and \n d. 6-12 membered bicyclic or bridged heterocycle optionally substituted with one, two, or three groups independently selected from R 4 ; \n R 3  is independently selected from \u2014F, \u2014Cl, \u2014Br, \u2014CH 3 , \u2014CH 2 F, \u2014CHF 2 , and \u2014CF 3 ; R 4  is selected from hydrogen, halogen, C 1 -C 3 alkyl, and C 1 -C 3 haloalkyl; and R 5  is selected from hydrogen, halogen, C 1 -C 3 alkyl, and C 1 -C 3 haloalkyl.

Metadata:
- Claim Count in Document: 128.0
- Percentile: 98.0
- Lexical Diversity: 1.18182
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15893295', '16169812', '15374966', '15764988', '15436587']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.760594822445081
- 35 USC 102 Novelty (BERT): 0.6312405018564011
- Combined Prediction Score: 0.7476593903862131
- Mean Citation Score: 421.216732
- Max Citation Score: 609.91235
- Similarity Product: 525.3618533393502

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test