PATENT CLAIM ANALYSIS

Application Number: 15899834
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "122000"]

Abstract:
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Claim (Index 1):
An engineered polypeptide having imine reductase activity, wherein said polypeptide has at least 90% sequence identity to SEQ ID NO:2, and comprises a substitution at a position corresponding to position 197 of SEQ ID NO:2, wherein the amino acid at position 197 has been replaced with proline or an aliphatic or a non-polar residue.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 88.0
- Lexical Diversity: 1.43243
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13890944', '15710462', '15048887', '15605061', '14887943']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8537537580124424
- 35 USC 102 Novelty (BERT): 0.8065766760231281
- Combined Prediction Score: 0.849036049813511
- Mean Citation Score: 1070.77044
- Max Citation Score: 1083.2335
- Similarity Product: 1037.664157261789

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test