PATENT CLAIM ANALYSIS

Application Number: 15763281
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["544", "238000"]

Abstract:
The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.

Claim (Index 1):
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein:\n A is selected from \n wherein \u201c \u201d denotes the point of attachment to B;\n B is selected from \n wherein \u201c*\u201d indicates the point of attachment to R 5  and \u201c**\u201d indicates the point of attachment to ring A;\n R 1  is selected from hydrogen, amino, \u2014CO 2 H, cyclopropyl, difluoromethyl, ethyl, halo, hydroxymethyl, methoxy, methoxymethyl, methyl, \u2014NHC(O)CH 3 , \u2014NHCO 2 CH 3 , trifluoromethoxy, trifluoromethyl, \n wherein R a  is selected from hydrogen, halo and methyl;\n R 2  is selected from hydrogen, cyano, \u2014CH 2 OH, halo, and methyl; \n R 3  is selected from hydrogen, cyano, cyclopropyl, difluoromethyl, fluoromethyl, halo, hydroxymethyl, methoxy, methyl, methylsulfonyl, trifluoromethoxy, trifluoromethyl, \u2014CH 2 N(CH 3 ) 2 , and a five-membered aromatic ring containing one, two, or three heteroatoms selected from nitrogen, oxygen, and sulfur; \n R 4  is selected from hydrogen, halo, and methyl; \n R 5  is selected from \n and\n R 6  is selected from hydrogen, ethyl, fluoromethyl, difluoromethyl, methyl, and trifluoromethyl; \n provided that when A is then B is or R 1  is selected from cyclopropyl, methoxymethyl, or R 5  is selected from

Metadata:
- Claim Count in Document: 26.0
- Percentile: 90.0
- Lexical Diversity: 1.23684
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15763280', '15300618', '15563697', '15865848', '13777144']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8022312374823206
- 35 USC 102 Novelty (BERT): 0.6517947847678345
- Combined Prediction Score: 0.787187592210872
- Mean Citation Score: 476.6418
- Max Citation Score: 616.3539
- Similarity Product: 604.076282505405

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test