PATENT CLAIM ANALYSIS

Application Number: 16307450
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["530", "322000"]

Abstract:
The invention provides Dsg2-derived peptides for inhibiting EMT and/or vasculogenic mimicry and treating and/or preventing angiogenesis-related diseases. Also provided are pharmaceutical compositions comprising the peptide of the invention and methods of using the peptide of the invention in inhibiting EMT and/or vasculogenic mimicry, and treating and/or preventing angiogenesis-related diseases.

Claim (Index 16):
The synthetic peptide of  claim 13 , wherein the modified peptide is the peptide having a synthetic polyamino acid polymer selected from the group consisting of: SEQ74 RRRMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200368)   SEQ75 RRRRMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200369)   SEQ76 RRRRRMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200370)   SEQ77 RRRRRRMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200371)   SEQ78 RRRRRRRMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200372)   SEQ79 MAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200373)   SEQ80 RRRMAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200374)   SEQ81 RRRRMAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200375)   SEQ82 RRRRRMAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200376)   SEQ83 RRRRRRMAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200377)   SEQ84 RRRRRRRMAEKWKIARDDD (SEQ\u2003ID\u2003NO:\u200378)   SEQ85 MAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200379)   SEQ86 RRRMAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200380)   SEQ87 RRRRMAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200381)   SEQ88 RRRRRMAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200382)   SEQ89 RRRRRRMAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200383)   SEQ90 RRRRRRRMAEKWKIARDDDD (SEQ\u2003ID\u2003NO:\u200384)   SEQ91 MAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200385)   SEQ92 RRRMAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200386)   SEQ93 RRRRMAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200387)   SEQ94 RRRRRMAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200388)   SEQ95 RRRRRRMAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200389)   SEQ96 RRRRRRRMAEKWKIARDDDDD (SEQ\u2003ID\u2003NO:\u200390)   SEQ97 MAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200391)   SEQ98 RRRMAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200392)   SEQ99 RRRRMAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200393)   SEQ100 RRRRRMAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200394)   SEQ101 RRRRRRMAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200395)   SEQ102 RRRRRRRMAEKWKIARDDDDDD (SEQ\u2003ID\u2003NO:\u200396)   SEQ103 DDDMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200397)   SEQ104 DDDDMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200398)   SEQ105 DDDDDMAEKWKIAR (SEQ\u2003ID\u2003NO:\u200399)   SEQ106 DDDDDDMAEKWKIAR (SEQ\u2003ID\u2003NO:\u2003100)   SEQ107 MAEKWKIARRRR (SEQ\u2003ID\u2003NO:\u2003101)   SEQ108 DDDMAEKWKIARRRR (SEQ\u2003ID\u2003NO:\u2003102)   SEQ109 DDDDMAEKWKIARRRR (SEQ\u2003ID\u2003NO:\u2003103)   SEQ110 DDDDDMAEKWKIARRRR (SEQ\u2003ID\u2003NO:\u2003104)   SEQ111 DDDDDDMAEKWKIARRRR (SEQ\u2003ID\u2003NO:\u2003105)   SEQ112 MAEKWKIRRRRRR (SEQ\u2003ID\u2003NO:\u2003106)   SEQ113 DDDMAEKWKIARRRRR (SEQ\u2003ID\u2003NO:\u2003107)   SEQ114 DDDDMAEKWKIARRRRR (SEQ\u2003ID\u2003NO:\u2003108)   SEQ115 DDDDDMAEKWKIARRRRR (SEQ\u2003ID\u2003NO:\u2003109)   SEQ116 DDDDDDMAEKWKIARRRRR (SEQ\u2003ID\u2003NO:\u2003110)   SEQ117 MAEKWKIARRRRRR (SEQ\u2003ID\u2003NO:\u2003111)   SEQ118 DDDMAEKWKIARRRRRR (SEQ\u2003ID\u2003NO:\u2003112)   SEQ119 DDDDMAEKWKIARRRRRR (SEQ\u2003ID\u2003NO:\u2003113)   SEQ120 DDDDDMAEKWKIARRRRRR (SEQ\u2003ID\u2003NO:\u2003114)   SEQ121 DDDDDDMAEKWKIARRRRRR (SEQ\u2003ID\u2003NO:\u2003115)   SEQ122 MAEKWKIARRRRRRR (SEQ\u2003ID\u2003NO:\u2003116)   SEQ123 DDDMAEKWKIARRRRRRR (SEQ\u2003ID\u2003NO:\u2003117)   SEQ124 DDDDMAEKWKIARRRRRRR (SEQ\u2003ID\u2003NO:\u2003118)   SEQ125 DDDDDMAEKWKIARRRRRRR (SEQ\u2003ID\u2003NO:\u2003119)   SEQ126 DDDDDDMAEKWKIARRRRRRR (SEQ\u2003ID\u2003NO:\u2003120)   SEQ127 MAEKWKIARRRRRRRR (SEQ\u2003ID\u2003NO:\u2003121)   SEQ128 DDDMAEKWKIARRRRRRRR (SEQ\u2003ID\u2003NO:\u2003122)   SEQ129 DDDDMAEKWKIARRRRRRRR (SEQ\u2003ID\u2003NO:\u2003123)   SEQ130 DDDDDMAEKWKIARRRRRRRR (SEQ\u2003ID\u2003NO:\u2003124)   SEQ131 DDDDDDMAEKWKIARRRRRRRR (SEQ\u2003ID\u2003NO:\u2003125)

Metadata:
- Claim Count in Document: 59.0
- Percentile: 98.0
- Lexical Diversity: 1.73333
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13992998', '14896521', '15395648', '14745562', '13516511']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6920541694956607
- 35 USC 102 Novelty (BERT): 0.5142059616979449
- Combined Prediction Score: 0.6742693487158891
- Mean Citation Score: 266.771986
- Max Citation Score: 268.7109
- Similarity Product: 175.9529057649135

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test