PATENT CLAIM ANALYSIS

Application Number: 16069487
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-07
Patent Classification: ["424", "133100"]

Abstract:
The present disclosure provides antibodies that bind Lymphocyte Activation Gene-3 (LAG-3). Also provided are methods of stimulating an immune response, inhibiting growth of tumor cells, and treating an autoimmune, inflammatory, or viral disease.

Claim (Index 44):
A method of treating cancer in a patient in need thereof, comprising administering to the patient an antibody or fragment thereof, wherein the antibody or fragment thereof has specificity to a human Lymphocyte Activation Gene-3 (LAG-3) protein and comprises a heavy chain variable region comprising heavy chain complementarity determining regions CDRH1, CDRH2, and CDRH3, and a light chain variable region comprising light chain complementarity determining regions CDRL1, CDRL2, and CDRL3, and wherein\n the CDRH1 comprises the amino acid sequence of SEQ ID NO:240 or an amino acid sequence derived from SEQ ID NO:240 with one or two amino acid substitution; the CDRH2 comprises the amino acid sequence of SEQ ID NO:241 or an amino acid sequence derived from SEQ ID NO:241 with one or two amino acid substitution; the CDRH3 comprises the amino acid sequence of SEQ ID NO:242 or an amino acid sequence derived from SEQ ID NO:242 with one or two amino acid substitution; the CDRL1 comprises the amino acid sequence of SEQ ID NO:243 or an amino acid sequence derived from SEQ ID NO:243 with one or two amino acid substitution; the CDRL2 comprises the amino acid sequence of SEQ ID NO:244 or an amino acid sequence derived from SEQ ID NO:244 with one or two amino acid substitution; and the CDRL3 comprises the amino acid sequence of SEQ ID NO:245 or an amino acid sequence derived from SEQ ID NO:245 with one or two amino acid substitution.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 95.0
- Lexical Diversity: 1.17143
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15166305', '15254315', '15636610', '14472116', '15211504']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6740773369621568
- 35 USC 102 Novelty (BERT): 0.5435024500237945
- Combined Prediction Score: 0.6610198482683205
- Mean Citation Score: 363.044838
- Max Citation Score: 381.17462
- Similarity Product: 304.95539991043086

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test