PATENT CLAIM ANALYSIS

Application Number: 16039512
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "449000"]

Abstract:
Disclosed is a transdermal preparation, comprising sequentially-stacked layers of a backing layer, a barrier layer, a drug adhesive layer and a release layer, wherein the drug adhesive layer contains a drug selected from the group consisting of fentanyl, an analogue thereof and a pharmaceutically-acceptable salt thereof, a skin permeation enhancer of the drug, and a polyacrylate adhesive, which shows a high skin permeation with a low drug dosage, equivalent to one with high drug dosage, by increasing the skin permeation rate of drug.

Claim (Index 1):
A transdermal preparation, comprising sequentially-stacked layers of a backing layer, a barrier layer, a drug adhesive layer and a release layer,\n wherein the drug adhesive layer comprises (a) a drug selected from the group consisting of fentanyl, an analogue and a pharmaceutically-acceptable salt thereof, (b) a skin permeation enhancer which is a combination of lauramine oxide, and N-dodecyl-2-pyrrolidone, and (c) a polyacrylate adhesive which is a non-functional polyacrylate adhesive, or a mixture of the non-functional polyacrylate adhesive and a carboxyl-containing polyacrylate adhesive , wherein the analogue is at least one selected from the group consisting of alfentanyl, sufentanyl, remifentanyl, 3-methylfentanyl, carfentanyl and a pharmaceutically acceptable salt thereof, wherein the backing layer is in contact with the barrier layer and the barrier layer having a layer thickness of 10 to 30 \u03bcm consists of a rubber-based adhesive and a tackifying resin, and the backing layer consists of at least one selected from the group consisting of polyester, polyolefin, polyurethane, polyvinylacetate, polyvinylidene chloride, polyethylene, ethylene vinyl acetate, polyethylene terephthalate, polybutylene terephthalate, and polyamide, wherein the transdermal preparation has 1.05 to 10.08 mg of the drug content per unit dosage, 3.0 to 6.5 \u03bcg/hr/cm 2  of skin permeation rate, and 50 to 95 wt % of drug releasing amount per unit dosage to the initial loading amount of drug.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 2.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14004889', '12084014', '11525683', '14274465', '13776452']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6996284519605603
- 35 USC 102 Novelty (BERT): 0.5175157869585039
- Combined Prediction Score: 0.6814171854603547
- Mean Citation Score: 277.45891600000004
- Max Citation Score: 294.15512
- Similarity Product: 215.2353185260582

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test