PATENT CLAIM ANALYSIS

Application Number: 16083128
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-04
Patent Classification: ["544", "277000"]

Abstract:
The invention provides a new convergent approach for the synthesis of 2′-fluoro-6′- methylene-carbocyclic adenosine (FMCA) and 2′-fluoro-6′-methylene-carbocyclic guanosine (FMCG) from a readily available starting material in eight steps. An efficient and practical methodology for stereospecific preparation of a versatile carbocyclic key intermediate, (1S,3R,4R)-3-tert-butoxy-4-(tert-butoxymethyl)-2-fluoro-5-methylenecyclopentanol (compound 8 of scheme 1A or a) in only six (6) steps is also provided. Prodrugs of these compounds are also prepared.

Claim (Index 3):
The process of  claim 2  wherein compound 2 is prepared from compound 1 in a single pot without purification and/or separation.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 97.0
- Lexical Diversity: 1.37705
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14631209', '15287805', '15609080', '14079412', '13107713']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7277187298202035
- 35 USC 102 Novelty (BERT): 0.5356080188529403
- Combined Prediction Score: 0.7085076587234771
- Mean Citation Score: 235.178488
- Max Citation Score: 306.3729600000001
- Similarity Product: 138.9514236168909

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test