PATENT CLAIM ANALYSIS

Application Number: 16011090
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["540", "560000"]

Abstract:
The present invention provides compounds that modulate protein function, to restore protein homeostasis, including cytokine, CK1α, GSPT1, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of diseases, disorders, or conditions associated with a protein, such as diseases, disorders, and conditions associated with cytokines, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, and cancer, are provided.

Claim (Index 43):
A compound of Formula (IIf): or a pharmaceutically acceptable salt thereof, wherein: R 1  and R 2  are each independently H, deuterium, hydroxyl, halogen, cyano, nitro, optionally substituted amino, optionally substituted C 1 -C 6  alkoxy, optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, optionally substituted C 3 -C 8  cycloalkyl, optionally substituted C 6 -C 10  aryl, optionally substituted 3 to 10-membered heterocyclyl, or optionally substituted 5 to 10-membered heteroaryl.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 94.0
- Lexical Diversity: 2.0
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15847628', '15916752', '15599401', '15892267', '15597671']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.767393861712784
- 35 USC 102 Novelty (BERT): 0.6581152415388799
- Combined Prediction Score: 0.7564659996953936
- Mean Citation Score: 489.465524
- Max Citation Score: 628.7185
- Similarity Product: 596.6906945752203

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test