PATENT CLAIM ANALYSIS

Application Number: 15777290
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["424", "186100"]

Abstract:
The invention provides lentiviral preparations containing a sulfonic acid buffer, such as 1,4-piperazinediethanesulfonic acid (PIPES), 2-(N-morpholino)ethanesulfonic acid (MES), and 3-morpholinopropane-1-sulfonic acid (MOPS), a sodium citrate buffer, or a phosphate buffer. The invention additionally encompasses methods of lentiviral purification as well as methods of transducing human cells.

Claim (Index 34):
The aqueous composition of  claim 29 , wherein one or more of said one or more signaling domains comprises a costimulatory domain comprising an intracellular domain of a costimulatory protein selected from the group consisting of CD27, CD28, 4-1BB (CD137), OX40, GITR, CD30, CD40, ICOS, BAFFR, HVEM, ICAM-1, lymphocyte function-associated antigen-1 (LFA-1), CD2, CDS, CD7, CD287, LIGHT, NKG2C, NKG2D, SLAMF7, NKp80, NKp30, NKp44, NKp46, CD160, B7-H3, and a ligand that specifically binds with CD83.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 93.0
- Lexical Diversity: 1.65789
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15106862', '12443153', '15022049', '13277900', '14412844']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7170386475364159
- 35 USC 102 Novelty (BERT): 0.502004876183985
- Combined Prediction Score: 0.6955352704011728
- Mean Citation Score: 254.641716
- Max Citation Score: 258.30765
- Similarity Product: 183.18461704316127

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test