PATENT CLAIM ANALYSIS

Application Number: 15875669
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["514", "016900"]

Abstract:
The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-κB and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (OCN), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN). Therefore, the superior activity and stability of the peptide of the present invention are useful for medicines, sanitary aids, or cosmetics.

Claim (Index 28):
A method for promoting osteogenic differentiation, the method comprising contacting cells with a composition comprising a peptide comprising the amino acid sequence of SEQ ID NO: 2.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 1.84848
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14906829', '15500178', '15307943', '12019567', '15329382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7652657345741903
- 35 USC 102 Novelty (BERT): 0.5659404385929433
- Combined Prediction Score: 0.7453332049760657
- Mean Citation Score: 323.308232
- Max Citation Score: 452.61108
- Similarity Product: 390.9789348877501

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test