PATENT CLAIM ANALYSIS

Application Number: 15899834
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "122000"]

Abstract:
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Claim (Index 12):
The process of  claim 8 , in which the suitable reaction conditions comprise:\n (a) substrate loading at about 10 g/L to 100 g/L; (b) about 0.1 g/L to about 50 g/L of the engineered polypeptide; (c) about 0.05 g/L (0.001 M) to about 2.5 g/L (0.050 M) of NAD(P)H; (d) a pH of about 6 to 10; (e) temperature of about 20\u00b0 to 50\u00b0 C.; and (f) reaction time of 2-120 hrs.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 88.0
- Lexical Diversity: 1.43243
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13890944', '15710462', '15048887', '15605061', '14887943']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.856010627844543
- 35 USC 102 Novelty (BERT): 0.7981508705981737
- Combined Prediction Score: 0.8502246521199062
- Mean Citation Score: 1070.77044
- Max Citation Score: 1083.2335
- Similarity Product: 1011.6231123934984

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test