PATENT CLAIM ANALYSIS

Application Number: 16254127
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-08
Patent Classification: ["536", "026140"]

Abstract:
The present disclosure relates to the field of nucleic acid chemistry, specifically to 5-position modified uridines as well as phosphoramidite and triphosphate derivatives thereof. The present disclosure also relates to methods of making and using the same.

Claim (Index 6):
An aptamer according to  claim 5 , wherein the aptamer is selected from a ribonucleic acid or a deoxyribonucleic acid, optionally wherein said aptamer further comprises at least one chemical modification comprising a chemical substitution at one or more positions independently selected from a ribose position, a deoxyribose position, a phosphate position, and a base position, optionally wherein said chemical modification is independently selected from the group consisting of a 2\u2032-position sugar modification, a 2\u2032-amino (2\u2032-NH 2 ), a 2\u2032-fluoro (2\u2032-F), a 2\u2032-O-methyl (2\u2032-OMe), 2\u2032-O-ethyl (2\u2032-OEt), 2\u2032-O-propyl (2\u2032-OPr), 2\u2032-O\u2014CH 2 CH 2 OCH 3 , a 5-position pyrimidine modification, a backbone modification, methylation, a 3\u2032 cap, and a 5\u2032 cap.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 99.0
- Lexical Diversity: 1.37931
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15914050', '14917056', '15650281', '14069798', '14216486']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6530967618669599
- 35 USC 102 Novelty (BERT): 0.5243309201438384
- Combined Prediction Score: 0.6402201776946478
- Mean Citation Score: 379.661352
- Max Citation Score: 450.5075
- Similarity Product: 295.78431976556783

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test