PATENT CLAIM ANALYSIS

Application Number: 15753541
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "134100"]

Abstract:
The present invention pertains to a fusion polypeptide for use in treating and/or preventing organ failure in a subject suffering from sepsis, said fusion polypeptide comprises at least (i) a first portion being a Fc portion of an immunoglobulin and (ii) a second portion comprising the extracellular portion of the human B7-H1 polypeptide or a variant thereof. Moreover, also encompassed by the invention is a polynucleotide encoding said fusion polypeptide for use in treating and/or preventing organ failure in a subject suffering from sepsis.

Claim (Index 4):
The method according to  claim 1 , wherein said extracellular portion of the human B7-H1 polypeptide or variant thereof is selected from the group consisting of:\n (a) a polypeptide having an amino acid sequence encoded by the nucleic acid sequence shown in SEQ ID NO: 1 or 5; (b) a polypeptide having an amino acid sequence shown in SEQ ID NO: 2 or 6; (c) a polypeptide remaining capable of binding to the PD1 polypeptide and having an amino acid sequence which is at least 70% identical to the amino acid sequence of the polypeptide of (a) or (b), and (d) a polypeptide remaining capable of binding to the PD1 polypeptide having an amino acid sequence according to (a) or (b) which comprises at least one of the following amino acid exchanges L27A, S34Y, D49S, Y56S, E58S, K62S, H69F, E72S, K75S, K89S, A98F, Q100S, R113Y, and S117Y.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 1.7037
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11932327', '12547129', '11931653', '09794210', '11361057']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.747236049630126
- 35 USC 102 Novelty (BERT): 0.5102609459170849
- Combined Prediction Score: 0.7235385392588219
- Mean Citation Score: 267.395784
- Max Citation Score: 271.38733
- Similarity Product: 196.60701819863257

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test