PATENT CLAIM ANALYSIS

Application Number: 15891802
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["424", "141100"]

Abstract:
Methods for identifying compounds that positively regulate connexin 43 hemichannels.

Claim (Index 9):
An in vivo method of using a monoclonal antibody, compounds or reagents to treat OA, comprising comprising administering a hemichannels blocking antibody to a subject at risk of developing or diagnosed with osteoarthritis.\n (a) injecting an antibody, compound or reagent into knee cap cavity. (b) Assessing the inhibition of activation of NF-\u03baB induced by IL-1\u03b2 (c) Assessing OA development by X-ray, histological analysis and physical movement.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 88.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14912986', '11883739', '14404358', '15012732', '10353549']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6571016198122265
- 35 USC 102 Novelty (BERT): 0.6125997692095346
- Combined Prediction Score: 0.6526514347519573
- Mean Citation Score: 364.173404
- Max Citation Score: 641.90094
- Similarity Product: 469.852200614984

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test