PATENT CLAIM ANALYSIS

Application Number: 16186077
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["514", "562000"]

Abstract:
Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.

Claim (Index 21):
A method of decreasing protein-aldehyde adducts in a human diagnosed with Parkinson's Disease,\n said method comprising: administering to the human an organosulfur composition comprising an effective amount of a mixed disulfide of a lipophilic mercaptan disulfide bonded to N-acetylcysteine, wherein the mixed disulfide is bonded as a two to one salt with a divalent cation; said lipophilic mercaptan selected from the group consisting of propyl mercaptan, propenyl mercaptan, and allyl mercaptan; wherein said lipophilic mercaptan reacts with an aldehyde within the lipid membranes of said human, said aldehyde being in the form of an aldehyde or in the form of a protein-aldehyde adduct, to produce a molecular conjugate of said lipophilic mercaptan and said aldehyde; thereby decreasing protein-aldehyde adducts in the human.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.36842
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15387181', '13694447', '13373878', '15530804', '10853415']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8088871566236899
- 35 USC 102 Novelty (BERT): 0.6316143026572051
- Combined Prediction Score: 0.7911598712270415
- Mean Citation Score: 490.64977000000016
- Max Citation Score: 592.0988
- Similarity Product: 558.4145046043873

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test