PATENT CLAIM ANALYSIS

Application Number: 15761725
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["514", "017800"]

Abstract:
The present invention relates to an agent which inhibits Kallikrein-8 for use in the treatment or prevention of Alzheimer's disease and/or its precursor stages, as well as to methods, kits and uses relating thereto, including diagnostic tools.

Claim (Index 18):
A kit comprising\n (a) a compound specifically binding to Kallikrein-8 protein or a probe specifically recognizing kallikrein-8 mRNA, and (b) one or more compound(s) capable of detecting at least one biomarker for the prediction and/or diagnosis of Alzheimer's disease and/or of a precursor stage of Alzheimer's disease, preferably wherein the at least one biomarker is for in vitro diagnosis, in particular for in vitro diagnosis in a bodily sample selected from cerebrospinal fluid sample, blood sample, such as plasma sample, whole blood sample and serum sample, urine sample and saliva sample, and a biopsy, in particular a brain tissue biopsy, more preferably wherein the at least one biomarker is selected from A\u03b2 and isoforms thereof, and combinations of A\u03b2 and isoforms thereof, Tau and isoforms thereof, and combinations of Tau and isoforms thereof, Neurogranin and miRNA107.

Metadata:
- Claim Count in Document: 21.0
- Percentile: 90.0
- Lexical Diversity: 1.10526
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12157664', '13393220', '14324289', '13701758', '11185907']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7566520028017186
- 35 USC 102 Novelty (BERT): 0.5212063543887457
- Combined Prediction Score: 0.7331074379604213
- Mean Citation Score: 308.592442
- Max Citation Score: 328.3323
- Similarity Product: 243.97558685397505

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test