PATENT CLAIM ANALYSIS

Application Number: 15758662
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["424", "078170"]

Abstract:
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.

Claim (Index 54):
A polymer bioactive conjugate according to  claim 42 , wherein Z is of formula selected from the group consisting of:\n (R) \u2014O\u2014 (D); \u2003\u2003(i) \n (R) -J-Ar\u2014O\u2014 (D); \u2003\u2003(ii) \n (R) -J-C1-C12alkylene-O\u2014 (D); \u2003\u2003(iii) \n (R) -J-Ar-J-C1-C12alkylene-O\u2014 (D); \u2003\u2003(iv) \n (R) -J-C1-C12alkylene-J-Ar-O\u2014 (D); \u2003\u2003(v) \n (R) -J-C1-C12alkylene-J-Ar-Q-C1-C12alkylene-O\u2014 (D); \u2003\u2003(vi) \n (R) \u2014OC(O)\u2014 (D); \u2003\u2003(vii) \n (R) -J-Ar\u2014OC(O)\u2014 (D); and \u2003\u2003(Viii) \n (R) -J-C1-C12alkylene-OC(O)\u2014 (D); \u2003\u2003(ix) \n wherein: (R) indicates the end of the linking group bonded to the R group in the polymer backbone and (D) indicates the end of the linking group bonded to the quinolone drug; Ar is optionally substituted aromatic or heteroaromatic hydrocarbon; and J is selected from \u2014O\u2014, \u2014C(O)\u2014, \u2014O\u2014C(O)\u2014, \u2014O\u2014C(O)\u2014O\u2014, \u2014C(O)\u2014O\u2014, \u2014C(O)OC(O)\u2014, \u2014C(O)NRaC(O)\u2014, \u2014OC(O)NRa-, \u2014NRaC(O)O\u2014, \u2014NRa-, \u2014NRaC(O)NRa-, \u2014NRaC(O)\u2014, \u2014C(O)NRa-, \u2014S\u2014, \u2014O\u2014C(S)\u2014, \u2014C(S)\u2014O\u2014, \u2014S\u2014C(O)\u2014, \u2014C(O)\u2014S\u2014, \u2014NRaC(S)\u2014, and \u2014C(S)NRa-, where Ra is hydrogen or C1 to C6 alkyl.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 90.0
- Lexical Diversity: 1.81132
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14772981', '15435784', '15458546', '14409612', '13082841']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8368766492421692
- 35 USC 102 Novelty (BERT): 0.5759166901030562
- Combined Prediction Score: 0.810780653328258
- Mean Citation Score: 466.697574
- Max Citation Score: 501.03647
- Similarity Product: 406.5916394094604

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test