PATENT CLAIM ANALYSIS

Application Number: 15891978
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "004000"]

Abstract:
A method is provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The method includes the steps of capturing the fraction-bound solid phase substrate and bringing an isolation buffer and the fraction-bound solid phase substrate into contact to purify the captured fraction-bound solid phase substrate.

Claim (Index 7):
A method for facilitating extraction of a fraction from a biological sample, the biological sample including non-desired material and a fraction-bound solid phase substrate, the method comprising the steps of:\n positioning at least a portion of a plunger within a passageway extending along axis through a barrel of a syringe, the plunger being slidable along the axis and including:\n an elongated stem having a first end received in the barrel; and \n a resilient plunger head extending radially from first end of the stem and terminating at a radially outer edge, the radially outer edge of the plunger head forming an airtight seal with an inner surface of the barrel; \n sliding the plunger along the axis of the barrel in a first direction such that the plunger head is positioned adjacent an opening in a first end of the barrel; positioning the opening in the first end of the barrel in fluid communication with an isolation buffer; sliding the plunger along the axis of the barrel in a second direction, opposite to the first direction, for a first user-selected distance so as to draw the isolation buffer into the passageway in the barrel through the opening; positioning the opening in the first end of the barrel in fluid communication with the biological sample; sliding the plunger along the axis of the barrel in a second direction for a second user-selected distance, so as to draw the biological sample into the passageway in the barrel through the opening; positioning a magnet adjacent to an outer surface of the barrel in proximity to the first end of the barrel such that a magnetic field generated by the magnet captures the fraction-bound solid phase substrate at a fixed location within the passageway through the barrel of the syringe; sliding the plunger along the axis of the barrel in the first direction for a third distance to urge the biological sample and at least a portion of isolation buffer from the passageway in the barrel through the opening and the captured fraction-bound solid phase substrate are maintained in the passageway in the barrel at the fixed location; removing the magnet from adjacent to an outer surface of the barrel such that the fraction-bound solid phase substrate is no longer captured at the fixed location within the passageway through the barrel of the syringe; and sliding the plunger along the axis of the barrel in the first direction such that the fraction-bound solid phase substrate is urged from the passageway in the barrel through the opening.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.77143
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13033351', '12713950', '14243086', '13604192', '13832860']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6099982423835189
- 35 USC 102 Novelty (BERT): 0.5041334365437901
- Combined Prediction Score: 0.599411761799546
- Mean Citation Score: 252.378954
- Max Citation Score: 281.75055
- Similarity Product: 207.15880376413463

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test