PATENT CLAIM ANALYSIS

Application Number: 15874140
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["546", "083000"]

Abstract:
The present invention provides tricyclic fused thiophene derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Claim (Index 70):
A method of treating a disease in a patient, comprising administering to said patient a compound, which is ((2R,5S)-5-{2-[(1R)-1-hydroxyethyl]-1H-imidazo[4,5-d]thieno[3,2-b]pyridin-1-yl}tetrahydro-2H-pyran-2-yl)acetonitrile, or a pharmaceutically acceptable salt thereof, wherein said disease is selected from allograft rejection, graft versus host disease, multiple sclerosis, rheumatoid arthritis, type I diabetes, lupus, Crohn's disease, myasthenia gravis, ulcerative colitis, psoriasis, contact dermatitis, prostate cancer, renal cancer, pancreatic cancer, breast cancer, lung cancer, Castleman's disease, lymphoma, leukemia, multiple myeloma, polycythemia vera (PV), essential thrombocythemia (ET), myelofibrosis (MF), chronic myelogenous leukemia (CML), chronic myelomonocytic leukemia (CMML), hypereosinophilic syndrome (HES), systemic mast cell disease (SMCD), myelodysplasic syndrome, bone resorption, osteoporosis, pemphigus vulgaris, asthma, scleroderma, ankylosing spondylitis, acute lymphoblastic leukemia (ALL), acute myelogenous leukemia (AML), cutaneous T-cell lymphoma (CTCL), mycosis, fungoides, colon cancer, colorectal cancer, acneiform rash, and cachexia.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.42857
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14872948', '14873078', '14068796', '14697236', '14289121']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7033434025355461
- 35 USC 102 Novelty (BERT): 0.5464872881139828
- Combined Prediction Score: 0.6876577910933898
- Mean Citation Score: 370.93873
- Max Citation Score: 398.03116
- Similarity Product: 318.4414687255144

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test