PATENT CLAIM ANALYSIS

Application Number: 16151766
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "255020"]

Abstract:
Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same. The systems may further comprise a bioactive agent. Related methods for making and using the biologically active agent delivery compositions are also provided. In certain embodiments, the pharmaceutically acceptable salts described can be formed by removal of solvent by methods including distillation, evaporation, spray drying or lyophilization.

Claim (Index 1):
A method of preparing a solid composition for drug delivery comprising:\n preparing a solution containing a biologically active agent and a pharmaceutically-acceptable salt of a heterocyclic compound in a solvent; and a step for removing said solvent; wherein said pharmaceutically acceptable salt of a heterocyclic compound has the structure according to Formula 1: wherein R 1  or R 2  comprise at least one carboxylate functional group; E 1  and E 2  are NH 2 ; and said salt further comprises at least one cation.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 97.0
- Lexical Diversity: 1.2807
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14991777', '15619087', '12886226', '14150474', '11210710']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8167503018661281
- 35 USC 102 Novelty (BERT): 0.6515349301031228
- Combined Prediction Score: 0.8002287646898275
- Mean Citation Score: 652.4935820000002
- Max Citation Score: 669.2931
- Similarity Product: 588.7901485635817

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test