PATENT CLAIM ANALYSIS

Application Number: 16065393
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "001650"]

Abstract:
The present invention is directed to novel non-invasive diagnostic took to dispose numerous disease states and/or conditions. The presets invention, represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these disease states. The novel imaging probe is capable of detecting infected cells, as well tissue. The methods described herein are able to diagnose, treat and/or monitor the therapy of numerous diseases and conditions including atherosclerosis, atherothrombosis, cerebral vascular disease, cerebral ischemia, cerebral infarct and meningitis as well as pneumonitis, pericarditis, multiple sclerosis, lupus erythematosus and pancreatitis, among others.

Claim (Index 1):
A method of diagnosing the existence of a ICAM-1/LFA-1 mediated disease or condition in tissue of a patient comprising administering to said patient an effective amount of at least one compound according to the chemical structure: Where Y is a chemical linker which links the nitrogen to a chelate group or tricarbonyl complex X, wherein X incorporates or complexes with a radioisotope, or a pharmaceutically acceptable salt thereof;\n measuring the amount of said compound which binds to said tissue in said patient; and comparing the measurement obtained in said measuring step with a standard from uninfected tissue or infected tissue, wherein said measurement obtained from said patient is compared to said standard(s) and said comparison is determined to be indicative of the existence or the absence of a disease or condition in said tissue, \n wherein said disease state or condition is atherosclerosis, the buildup of atherosclerotic plaque and/or atherothrombosis, cerebral vascular disease, cerebral ischemia, cerebral infarct and meningitis as well as pneumonitis, pericarditis, multiple sclerosis, lupus erythematosus or pancreatitis.

Metadata:
- Claim Count in Document: 51.0
- Percentile: 94.0
- Lexical Diversity: 1.52778
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13447918', '15261890', '12991253', '14093260', '13643412']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7201646287093983
- 35 USC 102 Novelty (BERT): 0.4754370766374916
- Combined Prediction Score: 0.6956918735022077
- Mean Citation Score: 244.28381200000004
- Max Citation Score: 247.1997
- Similarity Product: 237.0662046170533

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test