PATENT CLAIM ANALYSIS

Application Number: 16070661
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["435", "198000"]

Abstract:
Disclosed are various enzymatic processes for the enrichments of oils with omega-3 fatty acids, and specific lipase preparations for use with these processes.

Claim (Index 1):
An enzymatic process for the enrichment of n-3 polyunsaturated fatty acids (n-3 PUFA) as glycerides, said process comprising:\n (a) providing an oil having n-3 PUFA moieties content of from about 5% to about 60% w/w, the n-3 PUFA moieties be present as free acids or as acyl groups of glycerides and/or polar lipids contained in said oil; (b) adding to said oil, water or alkaline aqueous buffer solution at an amount of 0.2-10% w/w of said oil, to give a mixture with pH of from about 5 to about 9; (c) adding to the mixture obtained in step (b) a lipase, wherein said lipase is immobilized on a suitable polymeric support, wherein said lipase exhibits high selectivity toward saturated fatty acids, mono-, di- and tri-unsaturated fatty acids or their fatty acyl groups, and is capable of simultaneously or consecutively transesterifying, hydrolyzing and/or esterifying said oil; (d) providing an alkyl alcohol or alcohol donor, specifically short-chain alkyl alcohol or alcohol donor and adding, specifically step-wise adding said alcohol or alcohol donor to the mixture of said oil and said enzyme preparation obtained in step (c) to form a reaction system comprising said oil, said lipase preparation, said water or alkaline aqueous buffer solution and said alcohol, wherein said oil reacts with said alcohol, and allowing said reaction to reach a conversion of at least 40% of said oil to fatty acid alkyl esters (FAEEs), less than 10% free fatty acid (FFAs) and from about 15% to about 60% glycerides by weight of oil used in the reaction system; (e) stopping the reaction by removing the said reaction medium from said reaction system followed with evaporation, specifically flash evaporation to remove excess of alcohol and water to give a product comprising FAEEs, FFAs and a mixture of mono-, di- and tri-glycerides, and optionally polar lipids; and (f) isolating the said glycerides from said FAEEs and FFAs by distilling off said fatty acid alkyl esters and free fatty acids from the product obtained in step (e) to give a distillate comprising FAEEs and FFAs, and a residue comprising glycerides mixture and optionally polar lipids, wherein said mixture contains higher omega-3 fatty acids content compared to said oil, with recovery yield of higher than 60%.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 95.0
- Lexical Diversity: 1.13636
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12744761', '11946121', '15984796', '13597304', '14143258']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.661761505124459
- 35 USC 102 Novelty (BERT): 0.5445877370674046
- Combined Prediction Score: 0.6500441283187536
- Mean Citation Score: 380.249906
- Max Citation Score: 431.8138
- Similarity Product: 294.99838191663025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test