PATENT CLAIM ANALYSIS

Application Number: 16375843
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["428", "402000"]

Abstract:
Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.

Claim (Index 1):
A method of treating metabolic acidosis in a patient, the method comprising orally administering to the patient a pharmaceutical composition comprising a proton-binding, crosslinked amine polymer comprising the residue of an amine corresponding to Formula 1: wherein R 1 , R 2  and R 3  are independently hydrogen, hydrocarbyl, substituted hydrocarbyl provided, however, at least one of R 1 , R 2  and R 3  is other than hydrogen, the crosslinked amine polymer has an equilibrium swelling ratio in deionized water of less than 2, and the crosslinked amine polymer has an equilibrium proton binding capacity and a chloride binding capacity of at least 5 mmol/q in Simulated Gastric Fluid (\u201cSGF\u201d) containing 35 mM NaCl and 63 mM HCl at pH1.2 and 37\u00b0 C.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 100.0
- Lexical Diversity: 1.4
- Patent Class: 428.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16002306', '15715934', '16002269', '14944844', '14311852']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9294120179397516
- 35 USC 102 Novelty (BERT): 0.6447229851751096
- Combined Prediction Score: 0.9009431146632874
- Mean Citation Score: 602.0982339999998
- Max Citation Score: 669.8013
- Similarity Product: 569.7489578980208

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test