PATENT CLAIM ANALYSIS

Application Number: 15882603
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["435", "199000"]

Abstract:
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

Claim (Index 44):
A composition comprising a variant BsaI restriction endonuclease, wherein the variant BsaI restriction endonuclease is identical to the wild type BsaI restriction endonuclease of  B. stearothermophilus  6-55 except for an amino acid substitution at position 231.

Metadata:
- Claim Count in Document: 119.0
- Percentile: 86.0
- Lexical Diversity: 1.34
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13732831', '12172963', '13736406', '13736459', '13736529']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.727453667559742
- 35 USC 102 Novelty (BERT): 0.6282325287787207
- Combined Prediction Score: 0.7175315536816398
- Mean Citation Score: 653.2562260000002
- Max Citation Score: 702.8295
- Similarity Product: 516.8755331708193

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test