PATENT CLAIM ANALYSIS

Application Number: 15898381
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["424", "400000"]

Abstract:
The disclosure provides one-component, injectable, sustained release formulations which comprise microspheres containing active pharmaceutical ingredients (e.g., exenatide), wherein the microspheres are suspended in a non-aqueous carrier. The non-aqueous carrier can be an oil, a fractionated oil, triglycerides, diglycerides, monoglycerides, propylene glycol fatty acid diesters, and the like. The formulations offer distinct advantages of long shelf life for the stability and potency of the formulation and sustained release of active pharmaceutical ingredients to reduce the frequency of medication dosing and to increase patient compliance.

Claim (Index 1):
A manufactured pre-mixed formulation for injection comprising a suspension of:\n a pharmaceutically acceptable non-aqueous carrier comprising one or more triglycerides of C 6 -C 12  fatty acids; and microspheres comprising a biocompatible, biodegradable polymer and a GLP-1 receptor agonist; wherein the microspheres have a mean diameter of volume distribution of about 50 to 70 microns, and wherein the microspheres have an outer layer less porous than the inner layer.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.55556
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13060225', '11826535', '11521091', '11104877', '13084757']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7403552021522813
- 35 USC 102 Novelty (BERT): 0.5886450533431832
- Combined Prediction Score: 0.7251841872713716
- Mean Citation Score: 324.71972000000005
- Max Citation Score: 545.5761
- Similarity Product: 419.5020683552384

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test