PATENT CLAIM ANALYSIS

Application Number: 15901517
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["528", "371000"]

Abstract:
The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

Claim (Index 13):
The method of  claim 10 , wherein the tetradentate ligand is selected from the group consisting of: where:\n R 2a  and R 2a\u2032 , are independently a  (Z) m  group, hydrogen, \u2014OR, \u2014NR 2 , \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014SO 2 NR 2 ; \u2014CNO, \u2014NRSO 2 R, \u2014NCO, \u2014N 3 , \u2014SiR 3 ; or an optionally substituted radical selected from the group consisting of C 1-20  aliphatic; C 1-20  heteroaliphatic; phenyl; a 3- to 8-membered saturated or partially unsaturated monocyclic carbocycle, a 7-14 carbon saturated, partially unsaturated or aromatic polycyclic carbocycle; a 5- to 6-membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 3- to 8-membered saturated or partially unsaturated heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 6- to 12-membered polycyclic saturated or partially unsaturated heterocycle having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or an 8- to 10-membered bicyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur, \n R 1a , R 1a\u2032 , R 3a , and R 3a\u2032  are independently a  (Z) m  group, hydrogen, or an optionally substituted radical selected from the group consisting of C 1-20  aliphatic; C 1-20  heteroaliphatic; phenyl; a 3- to 8-membered saturated or partially unsaturated monocyclic carbocycle, a 7-14 carbon saturated, partially unsaturated or aromatic polycyclic carbocycle; a 5- to 6-membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 3- to 8-membered saturated or partially unsaturated heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 6- to 12-membered polycyclic saturated or partially unsaturated heterocycle having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or an 8- to 10-membered bicyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur, where any of [R 2a\u2032  and R 3a\u2032 ], [R 2a  and R 3a ], [R 1a  and R 2a ], and [R 1a\u2032  and R 2a\u2032]  may optionally be taken together with intervening atoms to form one or more rings which may in turn be substituted with one or more R d  groups; \n R d  at each occurrence is independently a  (Z) m  group, hydrogen, halogen, \u2014OR, \u2014NR 2 , \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014SO 2 NR 2 ; \u2014CNO, \u2014NRSO 2 R, \u2014NCO, \u2014N 3 , \u2014SiR 3 ; or an optionally substituted radical selected from the group consisting of C 1-20  aliphatic; C 1-20  heteroaliphatic; phenyl; a 3- to 8-membered saturated or partially unsaturated monocyclic carbocycle, a 7-14 carbon saturated, partially unsaturated or aromatic polycyclic carbocycle; a 5- to 6-membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 3- to 8-membered saturated or partially unsaturated heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 6- to 12-membered polycyclic saturated or partially unsaturated heterocycle having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or an 8- to 10-membered bicyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; where two or more R d  groups may be taken together with intervening atoms to form one or more optionally substituted rings optionally containing one or more heteroatoms, \n R 4b  is selected from the group consisting of: \n where\n R c  at each occurrence is independently a  (Z) m  group, hydrogen, halogen, \u2014OR, \u2014NR 2 , \u2014SR, \u2014CN, \u2014NO 2 , \u2014SO 2 R, \u2014SOR, \u2014SO 2 NR 2 ; \u2014CNO, \u2014NRSO 2 R, \u2014NCO, \u2014N 3 , \u2014SiR 3 ; or an optionally substituted radical selected from the group consisting of C 1-20  aliphatic; C 1-20  heteroaliphatic; phenyl; a 3- to 8-membered saturated or partially unsaturated monocyclic carbocycle, a 7-14 carbon saturated, partially unsaturated or aromatic polycyclic carbocycle; a 5- to 6-membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 3- to 8-membered saturated or partially unsaturated heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 6- to 12-membered polycyclic saturated or partially unsaturated heterocycle having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or an 8- to 10-membered bicyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; where two or more R c  groups may be taken together with the carbon atoms to which they are attached and any intervening atoms to form one or more optionally substituted rings; when two R c  groups are attached to the same carbon atom, they may optionally be taken together along with the carbon atom to which they are attached to form an optionally substituted moiety selected from the group consisting of: a 3- to 8-membered spirocyclic ring, a carbonyl, an oxime, a hydrazone, and an imine; \n R at each occurrence is independently hydrogen, an optionally substituted radical selected the group consisting of acyl; C 1-6  aliphatic; C 1-6  heteroaliphatic; carbamoyl; arylalkyl; phenyl; a 3- to 8-membered saturated or partially unsaturated monocyclic carbocycle, a 7-14 carbon saturated, partially unsaturated or aromatic polycyclic carbocycle; a 5- to 6-membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 3- to 8-membered saturated or partially unsaturated heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; a 6- to 12-membered polycyclic saturated or partially unsaturated heterocycle having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or an 8- to 10-membered bicyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; an oxygen protecting group; and a nitrogen protecting group, where two R groups on the same nitrogen atom can optionally be taken together to form an optionally substituted 3- to 7-membered ring, \n X is a nuclcophile capable of ring opening an epoxide; \n Y is a divalent linker selected from the group consisting of: \u2014NR\u2014, \u2014N(R)C(O)\u2014, \u2014C(O)NR\u2014, \u2014O\u2014, \u2014C(O)\u2014, \u2014OC(O)\u2014, \u2014C(O)O\u2014, \u2014S\u2014, \u2014SO\u2014, \u2014SO 2 \u2014, \u2014SiR 2 \u2014, \u2014C(\u2550S)\u2014, \u2014C(\u2550NR)\u2014, or \u2014N\u2550N\u2014; a polyether; a C 3  to C 8  substituted or unsubstituted carbocycle; and a C 1  to C 8  substituted or unsubstituted heterocycle; \n m\u2032 is 0 or an integer from 1 to 6, inclusive; \n m\u2032 is 0 or an integer from 1 to 4, inclusive; \n q is 0 or an integer from 1 to 4, inclusive; and \n x is 0, 1, or 2.

Metadata:
- Claim Count in Document: 67.0
- Percentile: 88.0
- Lexical Diversity: 1.4375
- Patent Class: 528.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15251668', '13059967', '13755120', '13755112', '13755126']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8315987777696615
- 35 USC 102 Novelty (BERT): 0.5682767154206296
- Combined Prediction Score: 0.8052665715347583
- Mean Citation Score: 485.4526900000001
- Max Citation Score: 496.68454
- Similarity Product: 364.8014976172829

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test