PATENT CLAIM ANALYSIS

Application Number: 16059301
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["424", "133100"]

Abstract:
Provided herein are materials and methods for delivering immunoglobulins (e.g. therapeutic immunoglobulins) across the blood-brain barrier.

Claim (Index 38):
A complex comprising:\n (a) a peptide comprising the sequence: (SEQ\u2003ID\u2003NO:\u20031) A p -L n -B m wherein i. A is an immunoglobulin affinity ligand; ii. L is a linker; and iii. B is a blood-brain barrier agent comprising the sequence: (SEQ\u2003ID\u2003NO:\u20033) L-R-X1-R-X2-X3-X4-H-L-R-X5-X6-X7-K-R-L-X8-R-D-X9; wherein: X1 is selected from the group consisting of A, L, S, and V; X2 is selected from the group consisting of L and M; X3 is selected from the group consisting of A and S; X4 is selected from the group consisting of N, S, and T; X5 is selected from the group consisting of K and N; X6 is selected from the group consisting of L, M, and V; X7 is selected from the group consisting of R and P; X8 is selected from the group consisting of L and M; X9 is selected from the group consisting of A and L; n is an integer from 0 to 50; m is an integer from 1 to 3; and p is an integer from 1 to 4; and (b) a therapeutic immunoglobulin.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.11111
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15246232', '13229900', '16092671', '15579988', '16092680']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7377164137191249
- 35 USC 102 Novelty (BERT): 0.5998116965770172
- Combined Prediction Score: 0.7239259420049141
- Mean Citation Score: 383.311028
- Max Citation Score: 531.6647
- Similarity Product: 478.7921391579092

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test