PATENT CLAIM ANALYSIS

Application Number: 16419555
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-09
Patent Classification: ["506", "016000"]

Abstract:
Methods and systems for sample preparation techniques that allow amplification (e.g., whole genome amplification) and sequencing of chromatin accessible regions of single cells are provided. The methods and systems generally operate by forming or providing partitions (e.g., droplets) including a single biological particle and a single bead comprising a barcoded oligonucleotide. The preparation of barcoded next-generation sequencing libraries prepared from a single cell is facilitated by the transposon-mediated transposition and fragmentation of a target nucleic acid sequence. The methods and systems may be configured to allow the implementation of single-operation or multi-operation chemical and/or biochemical processing within the partitions.

Claim (Index 13):
The method of  claim 12 , wherein said plurality of first barcode oligonucleotide molecules and said plurality of second barcode oligonucleotide molecules are releasably attached to said gel bead.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 100.0
- Lexical Diversity: 1.53521
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15842687', '15887947', '16052486', '15875899', '15933299']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6427084898322373
- 35 USC 102 Novelty (BERT): 0.6839670739676892
- Combined Prediction Score: 0.6468343482457826
- Mean Citation Score: 508.3598280000001
- Max Citation Score: 784.80084
- Similarity Product: 664.9892983780003

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test