PATENT CLAIM ANALYSIS

Application Number: 16056310
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["435", "440000"]

Abstract:
Described herein are methods and vectors for rational, multiplexed manipulation of chromosomes within open reading frames (e.g., in protein libraries) or any segment of a chromosome in a cell or population of cells, in which various CRISPR systems are used.

Claim (Index 8):
The method of  claim 1 , wherein a distance between the mutation preventing nuclease binding at the PAM or spacer and the mutation of at least one nucleotide relative to the target region on the editing cassette is at least 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 nucleotides.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 96.0
- Lexical Diversity: 1.24324
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15948785', '15116616', '15630909', '15948789', '15948798']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.807968212705506
- 35 USC 102 Novelty (BERT): 0.6264786529395534
- Combined Prediction Score: 0.7898192567289108
- Mean Citation Score: 682.8296280000002
- Max Citation Score: 752.7857700000003
- Similarity Product: 509.2612504484941

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test