PATENT CLAIM ANALYSIS

Application Number: 16217507
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["424", "093450"]

Abstract:
A method is provided for evaluating agents for the treatment of different intestinal motility disorders, using distinct methodological parts related to musculature and nerves of the GI tract which communicate with the brain. In particular, the present invention provides a method for the selection of an agent effective for the treatment of an intestinal motility disorder, wherein said method comprises: a) a step of spatiotemporal (ST) mapping carried out on a gastrointestinal segment to analyse the effect of said agent on gastrointestinal motility; and b) a step of ex vivo nerve bundle recording carried out on a gastrointestinal segment to analyse the effect of said agent on mesenteric afferent nerve firing. Bacterial strains selected by the methods of the invention and the use of said bacterial strains in the treatment of intestinal motility disorders are also provided.

Claim (Index 29):
The method of  claim 27 , wherein decreasing migrating motor complex (MMC) frequency and MMC velocity in the jejunum by the  Lactobacillus reuteri  bacterial strain increases the transit time of material through the jejunum when administered to a subject, thereby increasing nutrient absorption from the transiting material in the jejunum.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 98.0
- Lexical Diversity: 1.88608
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15705922', '14425470', '15389577', '15981244', '09374142']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7888774515723639
- 35 USC 102 Novelty (BERT): 0.5661131425217945
- Combined Prediction Score: 0.766601020667307
- Mean Citation Score: 407.036758
- Max Citation Score: 488.74036
- Similarity Product: 346.77303251634123

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test