PATENT CLAIM ANALYSIS

Application Number: 15994571
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["424", "125000"]

Abstract:
The present disclosure describes methods and compositions for the treatment of neurological disorders and related symptoms by the in vivo sequestration and excretion of microbial metabolites. These metabolites are related to neurological disorders such as autism and Parkinson's disease, as well as intestinal hyperpermeability (leaky gut) and gastrointestinal comorbidities associated with such disorders.

Claim (Index 1):
A method of treating a subject having a behavioral symptom of a neurological disorder associated with autism spectrum disorder or an anxiety disorder, comprising:\n administering to the subject a sequestrant composition which binds to at least a fraction of at least one intestinal metabolite present in the digestive tract of the subject to form a sequestrant-metabolite complex, such that the sequestrant-metabolite complex is eliminated from the digestive tract; wherein the at least one intestinal metabolite is associated with the development or presence of a behavioral symptom selected from the group consisting of repetitive behaviors, stereotyped behaviors, obsessive behaviors, deficits in social communication and anxiety; wherein the sequestrant composition comprises a multiplicity of biocompatible particles which are non-absorbable by the digestive tract of the subject.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 93.0
- Lexical Diversity: 1.34091
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14012769', '14925510', '13267748', '14866791', '15004218']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6250004995109506
- 35 USC 102 Novelty (BERT): 0.5124764996146305
- Combined Prediction Score: 0.6137480995213186
- Mean Citation Score: 184.843678
- Max Citation Score: 247.5951
- Similarity Product: 153.20459794253108

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test