PATENT CLAIM ANALYSIS

Application Number: 15776536
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "260100"]

Abstract:
The present invention relates to compounds of formulae I and H, or pharmaceutically acceptable salts or esters thereof. Further aspects of the invention relate to pharmaceutical compositions and therapeutic uses of said compounds in the treatment of diseases of uncontrolled cell growth, proliferation and/or survival, inappropriate cellular immune responses, inappropriate cellular inflammatory responses, or neurodegenerative disorders, preferably tauopathies, even more preferably, Alzheimer's disease.

Claim (Index 10):
A compound of formula (II), or a pharmaceutically acceptable salt or ester thereof, wherein: R b  is selected from alkyl, cycloalkyl and heterocycloalkyl, each of which may be optionally substituted by one or more groups selected from halo and alkoxy; R 1a  is selected from:\n CO\u2014NR 12a R 13a , wherein R 12a  and R 13a  are each independently selected from H, alkyl, cycloalkyl and mono or bicyclic heterocycloalkyl, wherein said alkyl group is optionally substituted by one or more (CH 2 ) m R 14a  groups, and said heterocycloalkyl is optionally substituted by one or more groups selected from R 10  and (CH 2 ) m R 14a ; or R 12a  and R 13a  are linked, together with the nitrogen to which they are attached, to form a heterocycloalkyl group optionally containing one or more additional heteroatoms, and optionally substituted by one or more groups select from R 10  and (CH 2 ) m R 14a ; \n hydroxyalkyl; \n COOH; and \n H; \n Z 1 , Z 2 , Z 3  and Z 4  are all C; R 6 , R 7 , R 8  and R 9  are each independently selected from H, CN, NO 2 , OH, alkoxy, NHCO-alkyl, halo and haloalkyl; or Z 1 , Z 3  and Z 4  are all C, Z 2  is N, R 7  is absent and R 6 , R 8  and R 9  are as defined above; or Z 2 , Z 3  and Z 4  are all C, Z 1  is N, R 6  is absent and R 7 , R 8  and R 9  are as defined above; m is an integer from 1 to 10; each R 10  and R 11  is independently alkyl; each R 14a  is independently selected from CO 2 R 10 , COOH, OH, alkoxy, haloalkyl, NH 2 , NHR 10 , NR 10 R 11 , heteroaryl and heterocycloalkyl, wherein said heterocycloalkyl is optionally further substituted by one or more R 10  groups.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 1.45098
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15776574', '14772693', '15337184', '12784916', '15949799']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7396107960473547
- 35 USC 102 Novelty (BERT): 0.5309322925337846
- Combined Prediction Score: 0.7187429456959977
- Mean Citation Score: 300.366344
- Max Citation Score: 356.07635
- Similarity Product: 314.3397599603504

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test