PATENT CLAIM ANALYSIS

Application Number: 16030815
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-03
Patent Classification: ["435", "455000"]

Abstract:
The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.

Claim (Index 10):
A method of making a somatic cell more susceptible to reprogramming to a cell having a less differentiated state, comprising: obtaining a somatic cell that comprises an exogenously introduced polynucleic acid encoding Oct4 protein, and an exogenously introduced polynucleic acid encoding Sox2 or Nanog protein; wherein the exogenously introduced polynucleic acids result in making the somatic cell more susceptible to reprogramming to a less differentiated state; and wherein the exogenous polynucleic acids are transiently transfected into the cell.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 95.0
- Lexical Diversity: 1.44737
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15588062', '12703061', '14923321', '13646444', '13646430']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6099958608914475
- 35 USC 102 Novelty (BERT): 0.5849744822853258
- Combined Prediction Score: 0.6074937230308354
- Mean Citation Score: 451.102838
- Max Citation Score: 475.77924
- Similarity Product: 462.3012515413928

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test