PATENT CLAIM ANALYSIS

Application Number: 16328039
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-07
Patent Classification: ["435", "006110"]

Abstract:
A method for detecting at least one specific microorganism in a sample is disclosed, wherein a probe nucleic acid sequence comprising at least one detectable label which is capable of emitting at least one detectable signal is provided, and wherein the detectable signal takes a first value when the probe sequence is not bound to the target sequence and a second value when the probe sequence is bound to the target sequence. At least one value of the detectable signal for the probe nucleic acid sequence is measured and analyzed, wherein it is indicated that the sample contains the microorganism if the measured value corresponds to the second value of the detectable signal. A significant difference between a probe sequence that hybridizes with a target sequence (signal ( 2 )) and a control sequence which does not bind to any target (signal ( 1 )) can be detected. Throughout all phases (heating, stationary and cooling) of a hybridization process, the value of the detectable signal ( 2 ) is higher than the value of the control signal ( 1 ), wherein the most significant difference can be observed at the end of the cooling phase (Δ 3 ) so that measuring and analyzing the detectable signal ( 2 ) during this period provides the most reliable result. Alternatively or optionally, additional measuring points in other phases (Δ 1  and/or Δ 2 ) can be set in order to enhance reliability of the result.

Claim (Index 6):
The method according to  claim 5 , wherein at least one value of the detectable signal in the sample is measured while the temperature is kept constant.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 99.0
- Lexical Diversity: 2.57843
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10196842', '11286573', '11203320', '11638655', '11701605']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6518158612317542
- 35 USC 102 Novelty (BERT): 0.509297340206204
- Combined Prediction Score: 0.6375640091291992
- Mean Citation Score: 239.224244
- Max Citation Score: 242.42976
- Similarity Product: 141.73614975362776

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test