PATENT CLAIM ANALYSIS

Application Number: 16105926
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-04
Patent Classification: ["536", "024500"]

Abstract:
The invention provides a method for generating an oligonucleotide with which an exon may be skipped in a pre-mRNA and thus excluded from a produced mRNA thereof. Further provided are methods for altering the secondary structure of an mRNA to interfere with splicing processes and uses of the oligonucleotides and methods in the treatment of disease. Further provided are pharmaceutical compositions and methods and means for inducing skipping of several exons in a pre-mRNA.

Claim (Index 42):
The oligonucleotide of  claim 35 , wherein the modification is a phosphorothioate internucleoside linkage.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 96.0
- Lexical Diversity: 1.57143
- Patent Class: 536.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13550210', '14198992', '14248279', '12976381', '11233495']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6571052231225001
- 35 USC 102 Novelty (BERT): 0.5745109202363046
- Combined Prediction Score: 0.6488457928338806
- Mean Citation Score: 500.966096
- Max Citation Score: 511.09448
- Similarity Product: 364.11949749644754

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test