PATENT CLAIM ANALYSIS

Application Number: 16070661
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["435", "198000"]

Abstract:
Disclosed are various enzymatic processes for the enrichments of oils with omega-3 fatty acids, and specific lipase preparations for use with these processes.

Claim (Index 10):
A process for the preparation of a mixture of glycerides having from about 30% to about 80% w/w, specifically from about 50% to 80% w/w, more specifically from about 50% to 70% w/w n-3 polyunsaturated fatty acids moieties, said process comprising:\n (a) providing an oil comprising n-3 polyunsaturated fatty acids, specifically from about 5% to about 60% w/w, said n-3 fatty acids being present as fatty acyl groups bonded to the glycerol backbone of glycerides or polar lipids in said oil and/or as free fatty acids, said oil also comprising free or esterified saturated fatty acids, mono-, di- and tri-unsaturated fatty acids; (b) adding to said oil, water or alkaline aqueous buffer solution at an amount of 0.2-10% w/w of said oil, to give a mixture with pH of from about 5 to about 9; (c) adding to the mixture obtained in step (b) a lipase, wherein said lipase is immobilized on a polymeric resin support, wherein said resin comprises alternating hydrophobic domains and mild hydrophilic domains, specifically hydrophobic domains comprised of hydrophobic aliphatic or aromatic monomers and mild hydrophilic domains comprised of acrylic and/or methacrylic esters, wherein said lipase exhibits high selectivity towards saturated fatty acids, mono-, di- and tri-unsaturated fatty acids or their fatty acyl group, and is capable of simultaneously or consecutively transesterifying, hydrolyzing and/or esterifying said oil; (d) providing an alkyl alcohol or alcohol donor, specifically short-chain alkyl alcohol or alcohol donor and adding, specifically step-wise adding said alcohol or alcohol donor to the mixture of said oil and said enzyme preparation obtained in step (c) to form a reaction system comprising said oil, said water or aqueous alkaline buffer solution, said lipase preparation and said alcohol, wherein said oil reacts with said alcohol, and allowing said reaction to reach a conversion of at least 40% of said oil to fatty acid alkyl esters (FAEEs), less than 10% free fatty acid (FFAs) and from about 15% to about 60% glycerides by weight of oil used in the reaction system; (e) stopping the reaction by removing the said reaction medium from said reaction system followed with evaporation, specifically flash evaporation of the reaction to remove excess of alcohol and water, to give a product comprising FAEEs, FFAs and a mixture of mono-, di- and tri-glycerides and optionally polar lipids; and (f) isolating the said glycerides mixture from said FAEEs and FFAs by distilling off said fatty acid alkyl esters and free fatty acids from the product obtained in step (e) to give a distillate comprising FAEEs and FFAs, and a residue comprising glycerides mixture, wherein said glycerides mixture optionally further comprises polar lipids contains higher omega-3 fatty acids content compared to said oil, with recovery yield of higher than 60%.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 95.0
- Lexical Diversity: 1.13636
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12744761', '11946121', '15984796', '13597304', '14143258']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.661443524371575
- 35 USC 102 Novelty (BERT): 0.5452453180795593
- Combined Prediction Score: 0.6498237037423735
- Mean Citation Score: 380.249906
- Max Citation Score: 431.8138
- Similarity Product: 301.14966107587816

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test