PATENT CLAIM ANALYSIS

Application Number: 16265286
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-05
Patent Classification: ["546", "026000"]

Abstract:
The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.

Claim (Index 30):
The process of any one of  claims 1  to  29 , wherein the compound of Formula I is a compound of Formula I(B) or Formula I(C): where each of X 1  and X 2  is O, N, or S, and each of R 1  to R 11  or R 1  to R 13  is independently selected from hydrogen, hydroxide, amino, halogen. C1-6-alkyl, C1-6-alkenyl, C1-C6 alkynyl, C1-C6 alkyl ketone, phenyl ketone, C1-C6 alkyl imine, phenyl imine, C1-C6 alkyl amide, benzyl amide, benzamide, C1-C6 alkyl ester, benzoyl, phenyl ester, carboxylate, C1-C6 alkyl carbonate, phenyl carbonate, carbamate, C1-C6 monoalkyl carbamate, C1-C6 dialkyl carbamate, phenyl carbamate, diphenyl carbamate, guanidine, C1-C6 alkyl ether, phenyl, benzyl, benzyl ether, phenyl ether, trifluoromethyl, trfluoromethoxy, trifluroacetate, sulfonic acid, C1-C6 alkyl sulfonate ester, trifluromethanesulfonate, toluenesulfonate, benzene sulfonate, phenyl sulfoxide, C1-C6 alkyl sulfoxide, nitro, cyano, isonitrile, C1-C6 epoxide, C1-C6 monoalkyl amine, C1-C6 dialkyl amine, diphenyl amine, phosphate, C1-C6 alkyl phosphate, C1-C6 dialkyl phosphate, phosphine, C1-C6 monoalkyl phosphine, C1-C6 dialkyl phosphine, phenyl phosphine, diphenylphosphine, C1-C6 monoalkyl phenyl phosphine, boronic acid, C1-C6 dialkyl boronic ester, diphenyl boronic ester, borate, C1-C6 dialkyl borate, and diphenyl borate; and Y is a negatively charged counter-ion, either a dianion or two monoanions.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 99.0
- Lexical Diversity: 1.14815
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15558808', '14131973', '14234382', '15566872', '12437711']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7743476436273965
- 35 USC 102 Novelty (BERT): 0.5208679035735463
- Combined Prediction Score: 0.7489996696220115
- Mean Citation Score: 221.041246
- Max Citation Score: 336.569
- Similarity Product: 282.6510474857092

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test