PATENT CLAIM ANALYSIS

Application Number: 15753508
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "043000"]

Abstract:
Methods of treatment and dosage regimes using a composition comprising a tetracycline antibiotic in treating or alleviating a disorder including EGFRI associated rash, EGFRI associated rash related symptoms, a tetracycline antibiotic responsive EGFRI associated rash related disorder, skin disorder caused by a bacteria, and a tetracycline antibiotic responsive sebaceous gland disease, P. EGFRI associated rash bacteria associated disorders and other superficial infections, including skin infections are provided.

Claim (Index 105):
A method for treating acne vulgaris in a subject in need thereof, comprising administering to the subject an effective amount of a minocycline antibiotic in a carrier according to a dosing schedule such that\n (a) the mean maximum plasma concentration of the tetracycline antibiotic is about 0.2 ng/mL to about 5 ng/mL after at least one day of use, and/or (b) the mean maximum plasma concentration of the tetracycline antibiotic is about 0.2 ng/mL to about 12 ng/mL after at least 16 days of use, and/or (c) the area under the plasma concentration versus time curve at the last time point with a detectable drug concentration equal to or greater than the limit of quantification (AUCT) is about 36 ng*h/mL to 132 ng*h/mL, wherein the carrier is essentially waterless and comprises: about 48% to about 51% soybean oil by weight of the topical composition, about 23% to about 25% coconut oil by weight of the topical composition, about 4% to about 6% cyclomethicone by weight of the topical composition,\n about 0.7% to about 2% light mineral oil by weight of the topical composition, \n about 3% to about 4% cetostearyl alcohol by weight of the topical composition, \n about 2% to about 4% stearic acid by weight of the topical composition, \n about 2% to about 3% myristyl alcohol by weight of the topical composition, about 1% to about 3% hydrogenated castor oil by weight of the topical composition, about 1% to about 3% beeswax by weight of the topical composition, about 1% to about 2% stearyl alcohol by weight of the topical composition, and about 0.5% to about 1.5% behenyl alcohol by weight of the topical composition, and wherein when the carrier is combined with propellant in an aerosol container to produce a foam.

Metadata:
- Claim Count in Document: 227.0
- Percentile: 88.0
- Lexical Diversity: 1.85
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15699692', '12795164', '13732024', '13831396', '15591733']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7919777052080328
- 35 USC 102 Novelty (BERT): 0.5283088835393941
- Combined Prediction Score: 0.765610823041169
- Mean Citation Score: 290.042484
- Max Citation Score: 353.14264
- Similarity Product: 240.7465961239052

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test