PATENT CLAIM ANALYSIS

Application Number: 16004921
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "001100"]

Abstract:
A binding moiety (B) for Carbonic Anhydrase IX (CAIX), the binding moiety comprising: The binding moiety is univalent, bivalent, or multivalent. A targeted therapeutic agent may comprise the binding moiety. The invention also includes a method for treating a disease expressing elevated levels of CAIX by administering the targeted therapeutic agent.

Claim (Index 3):
The targeted therapeutic agent of  claim 1 , wherein said compound has the formula: wherein:\n Hy is a hydrophilic moiety for improving the solubility of the conjugate; \n S\u2014S represents a cleavable disulfide bond between the drug moiety and the linker; \n Sp are spacer groups, independently selected from the group consisting of one or more optionally substituted straight or branched or cyclic C1-C6 alkylene, optionally substituted straight or branched or cyclic C1-C6 alkenylene, carbonyl carbons, ether, thioether O or S atoms, and amine N atoms; and \n R is selected from the group consisting of H, halogen, carboxylate, substituted or unsubstituted (hetero)alkyl, (hetero)alkenyl, (hetero)alkynyl, (hetero)aryl, (hetero)arylalkyl, (hetero)cycloalkyl, (hetero)cycloalkylaryl, heterocyclylalkyl, a peptide, an oligosaccharide, and a steroid group.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 94.0
- Lexical Diversity: 1.55
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15431310', '15124058', '14722307', '15477721', '13897911']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8057141183627432
- 35 USC 102 Novelty (BERT): 0.5722270459784745
- Combined Prediction Score: 0.7823654111243163
- Mean Citation Score: 324.67310600000013
- Max Citation Score: 537.9128400000002
- Similarity Product: 349.3829568306185

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test