PATENT CLAIM ANALYSIS

Application Number: 15750824
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-10
Patent Classification: ["506", "002000"]

Abstract:
Reagents and methods for the analysis of nucleic acids (e.g. genomic DNA) of circulating microparticles (i.e. microparticles originating from blood) are provided. The methods comprise linking at least two fragments of a target nucleic acid of a circulating microparticle to produce a set of at least two linked fragments of the target nucleic acid. In the methods, fragments of a target nucleic acid may be linked by techniques such as barcoding, partitioning, ligation and/or separate sequencing. The sequencing of a set of linked fragments provides a set of informatically linked sequence reads corresponding to the sequences of fragments from a single microparticle.

Claim (Index 59):
The method of  claim 58 , wherein prior to the step of appending the at least two fragments of genomic DNA of the circulating microparticle to a barcode sequence, or to different barcode sequences of a set of barcode sequences, the method comprises appending a coupling sequence to each of the fragments of genomic DNA of the circulating microparticle, wherein the coupling sequences are then appended to the barcode sequence, or to the different barcode sequences of a set of barcode sequences, to produce the set of linked fragments of genomic DNA.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 88.0
- Lexical Diversity: 1.94915
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15842687', '14990276', '14006971', '14316447', '14947988']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5639823123974712
- 35 USC 102 Novelty (BERT): 0.5390277159150095
- Combined Prediction Score: 0.561486852749225
- Mean Citation Score: 344.23017
- Max Citation Score: 360.96902
- Similarity Product: 250.8567057980132

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test