PATENT CLAIM ANALYSIS

Application Number: 15986656
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["514", "452000"]

Abstract:
The present invention provides methods for determining the selectivity of an anesthetic for an anesthetic-sensitive receptor by determining the molar water solubility of the anesthetic. The invention further provides methods for modulating the selectivity of an anesthetic for an anesthetic-sensitive receptor by altering or modifying the anesthetic to have higher or lower water solubility. The invention further provides methods of inducing anesthesia in a subject by administering via the respiratory pathways (e.g., via inhalational or pulmonary delivery) an effective amount of an anesthetic compound identified according to the present methods.

Claim (Index 1):
A method of inducing anesthesia in a subject, comprising administering to the subject via the respiratory system an effective amount of a compound or a mixture of compounds of Formula V: wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9  and R 10  independently are selected from H, X, CX 3 , CHX 2 , CH 2 X and C 2 X 5 ; and wherein X is a halogen, the compound has a vapor pressure of at least 0.1 atmospheres (76 mmHg) at 25\u00b0 C., and the number of hydrogen atoms of Formula V do not exceed the number of carbon atoms, thereby inducing anesthesia in the subject.

Metadata:
- Claim Count in Document: 145.0
- Percentile: 93.0
- Lexical Diversity: 1.95918
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14414089', '15186335', '15788034', '14618667', '11946174']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7496350298508749
- 35 USC 102 Novelty (BERT): 0.6140956639650819
- Combined Prediction Score: 0.7360810932622956
- Mean Citation Score: 386.527608
- Max Citation Score: 539.8117
- Similarity Product: 490.9673334954083

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test