PATENT CLAIM ANALYSIS

Application Number: 16137421
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-04
Patent Classification: ["435", "069700"]

Abstract:
The invention provides a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a Family B G-protein coupled receptor (GPCR) that comprises transmembrane helix (TM)-1, TM2 and TM3 of the GPCR; b) a stable protein domain; and c) a second portion of the GPCR comprising TM4, TM5, TM6 and TM7 of the GPCR. The invention also provides a method of crystallising a GPCR comprising providing the fusion protein of the invention and crystallising it to obtain crystals.

Claim (Index 6):
A fusion protein according to  claim 5 , wherein the stable protein domain is inserted into the ICL2 region of the GPCR after an amino acid corresponding to amino acid Phe 257 and before an amino acid corresponding to amino acid Ser 261 or Phe 260 or Val 259, according to the numbering of human GLP1R as set out in  FIG. 6 .

Metadata:
- Claim Count in Document: 41.0
- Percentile: 97.0
- Lexical Diversity: 1.86538
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14237678', '14133279', '13420329', '14684217', '13436709']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6829007525826838
- 35 USC 102 Novelty (BERT): 0.6578162253225898
- Combined Prediction Score: 0.6803922998566744
- Mean Citation Score: 417.032598
- Max Citation Score: 621.24963
- Similarity Product: 546.4612763953543

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test