PATENT CLAIM ANALYSIS

Application Number: 15756806
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["435", "006140"]

Abstract:
The present application relates to detection of changes in the number of nucleotides in short homopolymeric nucleic acid repeats, in particular in short homopolymeric microsatellites, for example for the purpose of diagnosing microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency in tumors. Accordingly, methods are provided for detecting changes in the number of nucleotides present in short homopolymeric nucleotide repeat sequences as well as kits and cartridges for automated detection of said changes.

Claim (Index 8):
The method according to  claim 7 , wherein the sequence-specific probe is a molecular beacon oligonucleotide probe and wherein said structural feature or modification is a 3\u2032-5\u2032exonuclease-activity resistant stem.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 90.0
- Lexical Diversity: 1.60784
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13860422', '11487156', '14506565', '11576597', '12109775']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6250253663382402
- 35 USC 102 Novelty (BERT): 0.510870774631079
- Combined Prediction Score: 0.6136099071675242
- Mean Citation Score: 255.72762200000005
- Max Citation Score: 278.07953
- Similarity Product: 182.3248382873571

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test