PATENT CLAIM ANALYSIS

Application Number: 15757135
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "249000"]

Abstract:
The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Claim (Index 1):
Compound of the formula in which R 1  is a group of the formula where * is the attachment point to the oxopyridine ring, R 6  is chlorine, R 7  is 2,2,2-trifluoroethoxy, 2,2-difluoroethoxy or 2-fluoroethoxy, R 8  is hydrogen, R 2  is methoxy, R 3  is C 1 -C 5 -alkyl, 3,3,3-trifluoro-2-methoxyprop-1-yl or 3,3,3-trifluoro-2-ethoxyprop-1-yl,\n where alkyl may be substituted by a substituent selected from the group consisting of fluorine, hydroxyl, difluoromethyl, trifluoromethyl, methoxy, ethoxy, tert-butoxy, isopropoxy, difluoromethoxy, trifluoromethoxy, C 3 -C 6 -cycloalkyl, 4- to 6-membered oxoheterocyclyl, 1,4-dioxanyl, oxazolyl, pyrazolyl, 5,6-dihydro-4H-1,2-oxazin-3-yl, phenyl, pyridyl, C 3 -C 6 -cycloalkyloxy and 4- to 6-membered oxoheterocyclyloxy,\n in which tert-butoxy and isopropoxy may be substituted by 1 to 3 fluorine substituents, \n and \n in which cycloalkyl may be substituted by 1 to 2 substituents selected independently from the group consisting of fluorine, hydroxyl, methyl, ethyl, methoxy, ethoxy, difluoromethyl, trifluoromethyl, difluoromethoxy and trifluoromethoxy, \n and \n in which oxoheterocyclyl may be substituted by 1 to 2 substituents selected independently from the group consisting of fluorine, methyl, ethyl, difluoromethyl and trifluoromethyl, \n and \n in which pyrazolyl is substituted by 1 or 2 substituents selected independently from the group consisting of fluorine, methyl and ethyl, \n and \n in which cycloalkyloxy and oxoheterocyclyloxy may be substituted by 1 to 2 substituents selected independently from the group consisting of fluorine and methyl, \n \n R 4  is hydrogen, R 5  is a group of the formula where # is the attachment point to the nitrogen atom, R 9  is hydroxycarbonyl or 5-membered heterocyclyl, R 10  is hydrogen, fluorine or methoxy, R 11  and R 12  together with the carbon atoms to which they are bonded form a 5-membered heterocycle,\n where the heterocycle may be substituted by 1 to 2 substituents selected independently from the group consisting of oxo, hydroxyl, hydroxycarbonyl, methyl, difluoromethyl and trifluoromethyl, \n R 13  is hydrogen or fluorine, R 14  is hydrogen or fluorine, R 15  is hydrogen or fluorine, R 16  is hydrogen, C 1 -C 4 -alkyl or cyclopropyl, R 17  is hydrogen or fluorine, R 18  is hydroxyl or \u2014NHR 19 ,\n in which \n R 19  is hydrogen, C 1 -C 4 -alkyl or cyclopropyl, \n R 20  is hydrogen or fluorine, or one of the salts thereof, solvates thereof or solvates of the salts thereof.

Metadata:
- Claim Count in Document: 48.0
- Percentile: 90.0
- Lexical Diversity: 1.51515
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15032212', '15513930', '14780925', '15513853', '15514276']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8287446412679851
- 35 USC 102 Novelty (BERT): 0.5721830832418726
- Combined Prediction Score: 0.8030884854653739
- Mean Citation Score: 436.271284
- Max Citation Score: 448.98108
- Similarity Product: 413.4821388991643

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test