PATENT CLAIM ANALYSIS

Application Number: 15774868
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "043000"]

Abstract:
The present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore, the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.

Claim (Index 15):
A 1,1\u2032-sulfanediyl-di-\u03b2-D-galactopyranoside compound of formula (1) wherein A is a group of formula 2 wherein R 1 -R 5  are independently selected from the group consisting of: H; Cl; Br; I; F; methyl optionally substituted with one or more fluorine atoms (F); R 7 O\u2014, wherein R 7  is a C 1-3  alkyl optionally substituted with one or more F; NH 2 ; OH; CN; NH 2 \u2014COR 8 , wherein R 8  is selected from C 1-3  alkyl optionally substituted with one or more F; and OCH 3  optionally substituted with one or more F; and B is a group of formula 3 wherein R 6  and R 9  are independently selected from the group consisting of: H; Cl; Br; I; F; NR 10 R 11 ; OR 12 ; C(\u2550O)\u2014R 13 ; CN; O(C\u2550O)\u2014R 16 ; NH(C\u2550O)\u2014R 17 ; C(\u2550O)\u2014OR 21 ; C(\u2550O)\u2014NR 22 R 23 ; SR 18 ; S(\u2550O)\u2014R 19 ; SO 2 R 20 ; a C 1-10  alkyl, optionally substituted with one or more: F; Oxo; NR 14 R 15 ; OR 24 ; C(\u2550O)\u2014R 25 ; CN; O(C\u2550O)\u2014R 26 ; NH(C\u2550O)\u2014R 27 ; C(\u2550O)\u2014OR 28 ; C(\u2550O)\u2014NR 29 R 30 ; SR 31 ; S(\u2550O)\u2014R 32 ; or SO 2 R 33 ; a C 3-7  cycloalkyl, optionally substituted with one or more: F; Oxo; NR 34 R 35 ; OR 36 ; C(\u2550O)\u2014R 37 ; CN; O(C\u2014O)\u2014R 38 ; NH(C\u2550O)\u2014R 39 ; C(\u2550O)\u2014OR 40 ; C(\u2550O)\u2014NR 41 R 42 ; SR 43 ; S(\u2014O)\u2014R 44 ; SO 2 R 45 ; or C 1-4  alkyl optionally substituted with one or more F; a branched C 3-10  alkyl, optionally substituted with one or more: F; Oxo; NR 46 R 47 ; OR 48 ; C(\u2550O)\u2014R 49 ; CN; O(C\u2550O)\u2014R 50 ; NH(C\u2550O)\u2014R 51 ; C(\u2550O)\u2014OR 52 ; C(\u2550O)\u2014NR 53 R 54 ; SR 55 ; S(\u2550O)\u2014R 56 ; SO 2 R 57 ; or a C 1-4  alkyl optionally substituted with F; and a 4-7-membered heterocyclic group being saturated or unsaturated and having 1-3 hetero atoms and 3-6 carbon atoms, optionally substituted with a C 1-4  alkyl optionally substituted with one or more: F; Oxo; NR 58 R 59 ; OR 60 ; C(\u2550O)\u2014R 61 ; CN; O(C\u2550O)\u2014R 62 ; NH(C\u2014O)\u2014R 63 , SR 64 ; S(\u2550O)\u2014R 65 ; or SO 2 R 66 ; wherein R 10 -R 66  are independently selected from the group consisting of: H; a C 1-10  alkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F, and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a C 3-7  cycloalkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a branched C 3-10  alkyl, optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a 4-7-membered heterocyclic group being saturated or unsaturated and having 1-3 hetero atoms and 3-6 carbon atoms optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a OC 1-10  alkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a OC 3-7 cycloalkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a O-(4-7-membered heterocyclic group being saturated or unsaturated and having 1-3 hetero atoms and 3-6 carbon atoms) optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a NHC 1-10  alkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; a NHC 3-7 cycloalkyl optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; and SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; and a NH-(4-7-membered heterocyclic group being saturated or unsaturated and having 1-3 hetero atoms and 3-6 carbon atoms) optionally substituted with one or more: F; oxo; CN; OCH 3 ; OCF 3 ; OCH 2 CH 3 , optionally substituted with one or more F; or SCH 2 CH 3 , optionally substituted with one or more F, SCH 3 , SCF 3 , OCH 3 , or OCF 3 ; or a pharmaceutically acceptable salt or solvate thereof.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 93.0
- Lexical Diversity: 2.60606
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15535837', '15323967', '11561465', '13266960', '14053797']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8282745396233114
- 35 USC 102 Novelty (BERT): 0.5644128955031754
- Combined Prediction Score: 0.8018883752112979
- Mean Citation Score: 372.047512
- Max Citation Score: 462.77826
- Similarity Product: 371.9078969005465

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test