PATENT CLAIM ANALYSIS

Application Number: 15945549
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "118000"]

Abstract:
The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.

Claim (Index 18):
A process of preparing compound (1) comprising a step of contacting a substrate of compound (2) with an engineered polypeptide having transaminase activity comprising an amino acid sequence having at least 80% sequence identity to reference sequence of SEQ ID NO:2 and an amino acid residue difference in position 215 of SEQ ID NO:2, in the presence of an amino group donor under suitable reaction conditions.

Metadata:
- Claim Count in Document: 101.0
- Percentile: 91.0
- Lexical Diversity: 1.66667
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15443792', '14768408', '14342713', '15449677', '14799180']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6880436854915624
- 35 USC 102 Novelty (BERT): 0.6583918873074288
- Combined Prediction Score: 0.6850785056731491
- Mean Citation Score: 534.0153799999998
- Max Citation Score: 735.4903
- Similarity Product: 613.0022518900038

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test