PATENT CLAIM ANALYSIS

Application Number: 15966513
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
Methods and techniques to increase the reliability of detecting virus infections, particularly lymphotropism, to eliminate false negative reactions in testing blood for the presence of lymphotropic viruses during enzyme immunoassay (EIA) and polymerase chain reaction (PCR) testing, and to better detect viruses with lymphotropism in biological materials having a concentration of virus particles lower than the sensitivity threshold of existing EIA and PCR methods, thereby making the techniques of the present invention more reliable.

Claim (Index 13):
A method for the detection of viruses with lymphotropism properties in a biological material with a low virus concentration, comprising:\n collecting a biological material from a patient; obtaining a lymphocyte suspension from a blood sample of at least one healthy human subject; forming an admixture of an equal amount of said biological material with said lymphocyte suspension; stirring and incubating the admixture; washing-out the lymphocytes from the admixture; removing lymphocyte membranes from the admixture, separating the lymphocyte cytoplasm content by centrifugation; and detecting the presence or absence of the virus RNA or DNA in the lymphocyte cytoplasm content, wherein the presence of the virus RNA or DNA in the lymphocyte cytoplasm content indicates the preserved viability of viruses in said biological sample of said patient, wherein the absence of the virus RNA or in the lymphocyte cytoplasm content indicates the loss of virus viability in said biological sample of said patient, and wherein said low virus concentration is below enzyme immunoassay (EIA) and polymerase chain reaction (PCR) testing sensitivity thresholds.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 1.45614
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15257663', '14397680', '15342471', '14889370', '15608300']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7695737757637069
- 35 USC 102 Novelty (BERT): 0.6001418816061586
- Combined Prediction Score: 0.7526305863479521
- Mean Citation Score: 414.689924
- Max Citation Score: 576.5979
- Similarity Product: 456.5742875164746

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test