PATENT CLAIM ANALYSIS

Application Number: 15762251
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["424", "009100"]

Abstract:
An object is to provide a polymer having a high tumor/blood ratio. The present invention provides a polymer represented by the following formula (P1): wherein in the formula (P1), R represents any of a residue derived from a polymerization initiator, or a functional group; A may not be present, and when present, A represents any of a low-molecular compound, a dye, a reporter molecule, a target-binding molecule, a polymer or D; L represents a linker and L may not be present; n 1  represents an integer of 1 or more; and D represents a dye backbone of a dye having absorption in the near-infrared region.

Claim (Index 2):
The polymer according to  claim 1 , wherein D is represented by formula (d1) or (d2): wherein, in the formula (d1): L 11 , L 12 , L 13 , L 14  and L 15  may be each the same or different, and represent CH or CR 15 , and L 11 , L 12 , L 13 , L 14  and L 15  may be taken together to form a 4-membered ring to a 6-membered ring; R 15  represents a straight or branched alkyl group having 1 to 10 carbon atoms; R 11 , R 12 , R 13  and R 14  may be each the same or different, and represent a hydrogen atom, a straight or branched alkyl group having 1 to 10 carbon atoms, \u2014R C1 \u2014SO 3 \u2212  or \u2014R D1 \u2014SO 3 X 11 ; R C1  and R D1  represent a straight or branched alkylene group having 1 to 10 carbon atoms; X 11  represents any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; R A1  represents a straight or branched alkyl group having 1 to 10 carbon atoms, \u2014R E1 \u2014SO 3 \u2212 , \u2014R F1 \u2014SO 3 X 12 , or \u2014R G1 \u2014CO 2 X 13 , and when R A1  represents the straight or branched alkyl group having 1 to 10 carbon atoms, a halogen ion or an organic acid ion may be included as a counter ion; X 12  and X 13  represent any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; R E1 , R F1  and R G1  represent a straight or branched alkylene group having 1 to 10 carbon atoms; R B1  represents a straight or branched alkylene group having 1 to 10 carbon atoms; Z 11  represents a hydrogen atom or \u2014SO 3 X 14 , or is taken together with an indole ring bound to Z 11  to form a cyclic aromatic ring including a benz[e]indole ring, a benz[f]indole ring or a benz[g]indole ring, and a hydrogen atom in the cyclic aromatic ring may be substituted with a straight or branched alkyl group having 1 to 10 carbon atoms, a straight or branched alkoxy group having 1 to 10 carbon atoms, or \u2014SO 3 X 15 ; X 14  and X 15  represent any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; and * represents binding to L, or represents binding to a carbon atom at a terminal of a repeating unit in the formula (P1) when L is absent; and wherein, in the formula (d2): L 101 , L 102 , L 103 , L 104 , L 105 , L 106  and L 107  may be each the same or different, and represent CH or CR 105 , and R 105  represents a straight or branched alkyl group having 1 to 10 carbon atoms, and L 101 , L 102 , L 103 , L 104 , L 105 , L 106  and L 107  may be taken together to form a 4-membered ring to a 6-membered ring; R 101 , R 102 , R 103  and R 104  may be each the same or different, and represent a hydrogen atom, a straight or branched alkyl group having 1 to 10 carbon atoms, \u2014R C11 \u2014SO 3 \u2212 , or \u2014R D11 \u2014SO 3 X 101 ; R C11  and R D11  represent a straight or branched alkylene group having 1 to 10 carbon atoms; X 101  represents any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; R A11  represents a straight or branched alkyl group having 1 to 10 carbon atoms, \u2014R E11 \u2014SO 3 \u2212 , \u2014R F11 \u2014SO 3 X 102 , or \u2014R G11 \u2014CO 2 X 103 , and when R A11  represents the straight or branched alkyl group having 1 to 10 carbon atoms, a halogen ion or an organic acid ion may be included as a counter ion; X 102  and X 103  represent any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; R E11 , R F11  and R G11  represent a straight or branched alkylene group having 1 to 10 carbon atoms; R B11  represents a straight or branched alkylene group having 1 to 10 carbon atoms; Z 101  represents a hydrogen atom or \u2014SO 3 X 104 , or is taken together with an indole ring bound to Z 101  to form a cyclic aromatic ring including a benz[e]indole ring, a benz[f]indole ring or a benz[g]indole ring, and a hydrogen atom in the cyclic aromatic ring may be substituted with a straight or branched alkyl group having 1 to 10 carbon atoms, a straight or branched alkoxy group having 1 to 10 carbon atoms, or \u2014SO 3 X 105 ; X 104  and X 105  represent any of a hydrogen atom, a sodium atom, a potassium atom, or a cation derived from ammonia, triethylamine, lysine or arginine; and * represents binding to L, or represents binding to the carbon atom at the terminal of the repeating unit in the formula (P1) when L is absent.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 90.0
- Lexical Diversity: 1.90769
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14413402', '14413399', '14767362', '14413400', '15513035']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7565506699464766
- 35 USC 102 Novelty (BERT): 0.518965123147699
- Combined Prediction Score: 0.7327921152665988
- Mean Citation Score: 266.24088
- Max Citation Score: 294.33884
- Similarity Product: 186.77568615339283

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test