PATENT CLAIM ANALYSIS

Application Number: 15780642
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["549", "464000"]

Abstract:
The present invention relates to medical chemistry technique field, particularly relates to a preparation method for amorphous darunavir crystal, The present invention provides a preparation method for preparing amorphous form of darunavir using an anti-solvent method. It can be a different method compared to the evaporation and concentration process disclosed in WO2011048604. Although the same with WO2013114382, anti-solvent are used, the target crystal form are truly different. The crystal form of WO2013114382 is solvent-free darunavir crystal, while an amorphous form of darunavir in the present application.

Claim (Index 1):
A preparation method of an amorphous darunavir crystal, wherein, comprising the following steps:\n a. Adding darunavir into the soluble solvent, b. after dissolved, take it into anti-solvent, c. isolated to obtain amorphous darunavir crystal.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 94.0
- Lexical Diversity: 1.86275
- Patent Class: 549.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13496642', '15211525', '14363149', '13261929', '14325869']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6915798168694987
- 35 USC 102 Novelty (BERT): 0.4670643271689798
- Combined Prediction Score: 0.6691282678994468
- Mean Citation Score: 156.221674
- Max Citation Score: 170.38237
- Similarity Product: 134.74429470728936

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test