PATENT CLAIM ANALYSIS

Application Number: 16036595
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "489000"]

Abstract:
Methods for making inhalable composite particles comprising a pharmaceutically-active agent, the method comprising: a) providing composite particles comprising a millable grinding matrix and a solid pharmaceutically-active agent, wherein the pharmaceutically-active agent has an median particle size on a volume average basis between 50 nm and 3 μm; and b) milling the composite particles in a mill without milling bodies for a time period sufficient to produce inhalable composite particles having a mass median aerodynamic diameter between 1 μm and 20 μm are described.

Claim (Index 108):
The inhalable pharmaceutically-active composition of  claim 106 , wherein the composite particles have a mass median aerodynamic diameter (MMAD) uniformity ratio of less than or equal to about 1.2 when delivered from a dry powder inhaler and analyzed with a Next Generation Impactor (NGI) with an induction port and a preseparator, wherein the distribution of each of the first and second pharmaceutically active agent is assayed and each is used to calculate an mass median aerodynamic diameter (MMAD) for the composite particle.

Metadata:
- Claim Count in Document: 227.0
- Percentile: 95.0
- Lexical Diversity: 1.57895
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13982630', '12208247', '14628148', '14202262', '10571146']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7831345817240559
- 35 USC 102 Novelty (BERT): 0.5142099154423608
- Combined Prediction Score: 0.7562421150958865
- Mean Citation Score: 289.278632
- Max Citation Score: 300.32755
- Similarity Product: 220.99440953917505

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test