PATENT CLAIM ANALYSIS

Application Number: 15893804
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["514", "264110"]

Abstract:
A method for inhibiting androgen activity, including administering an effective amount of a tetrahydropyridopyrimidine compound of formula (I) or a pharmaceutically acceptable salt thereof to a subject in need thereof, and a method for treating tumor, including administering an effective amount of a tetrahydropyridopyrimidine compound of formula (I) or a pharmaceutically acceptable salt thereof to a subject in need thereof

Claim (Index 28):
The method of  claim 23 , wherein, in the formula (I), R is selected from the group consisting of: where R 1  is a hydrogen atom; where R 1  is \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, Rf is a methyl group substituted with Rfa or an ethyl group substituted with Rfa, Rfa is a methylpyrazolyl group or an oxadiazolyl group, and n is 0; where R 1  is a phenyl group, a hydroxy-ethyl group, a hydroxy-isopropyl group, a methoxy group, an isopropoxy group, an ethoxy group substituted with a methylpyrazolyl group, or an n-propoxy group substituted with a methylsulfonylpiperazinyl group; where R 1  is a hydroxy-isopropyl group, a hydroxy-cyclopropyl group, a hydroxy-cyclobutyl group, an isopropoxy group, an ethoxy group substituted with a triazolyl group, a 2-methylpropoxy group substituted with a triazolyl group, a 2-methylpropoxy group substituted with a tetrazolyl group, a cyclopropylaminosulfonyl group, a 2,2,2-trifluoroethoxycarbonylamino group, a 2,2,2-trifluoroethylcarbonylamino group, or \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, R 2  is a hydrogen atom, a fluorine atom, or a chlorine atom, Rf is a 2,2-difluoroethyl group, a 2,2,2-trifluoroethyl group, a methyl group substituted with Rfa, or an ethyl group substituted with Rfa, Rfa is a trifluoromethylthiazolyl group, an oxadiazolyl group, or a trifluoromethyloxadiazolyl group, and n is 0 or 1; where R 1  is a hydroxy-isopropyl group, a 1,4-oxazepanylsulfonyl group, or \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, R 2  is a hydrogen atom or a trifluoromethyl group, Rf is a 2,2,2-trifluoroethyl group or an ethyl group substituted with Rfa, Rfa is an oxadiazolyl group, and n is 0; where R 1  is a hydroxy-isopropyl group or \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, Rf is a 2,2-difluoroethyl group, a 2,2,2-trifluoroethyl group, a hydroxy-2-methylpropyl group, a hydroxycyclohexyl group, a hydroxycyclopropylmethyl group, and n is 0; where R 1  is \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, Rf is a hydroxy-2-methylpropyl group, and n is 0; where R 1  is \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, Rf is a hydroxy-2-methylpropyl group, and n is 0; where R 1  is \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NHRf, Rf is a 2,2,2-trifluoroethyl group, and n is 0; where R 1  is a piperidinecarbonyl group substituted with a hydroxy-isopropyl group; and where R 1  is a piperidinecarbonyl group substituted with a hydroxy-isopropyl group.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 2.09375
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15203059', '15023894', '15771487', '13391895', '14923525']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8222177159871388
- 35 USC 102 Novelty (BERT): 0.6839788966780684
- Combined Prediction Score: 0.8083938340562317
- Mean Citation Score: 506.41254799999984
- Max Citation Score: 695.1665
- Similarity Product: 672.1650182595254

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test