PATENT CLAIM ANALYSIS

Application Number: 15938380
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["435", "252300"]

Abstract:
Genetically engineered cells and methods are presented that allow for the production of various value products from CO 2 . Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO 2  fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.

Claim (Index 1):
A metabolically engineered cell having a native CBB cycle, comprising:\n a recombinant nucleic acid comprising a nucleic acid sequence encoding a first enzyme and a second enzyme;\n wherein the first enzyme is a phosphoketolase enzyme (EC 4.1.2.9), that utilizes an intermediate of the CBB pathway as a substrate, and generates a first acetyl phosphate product; and the second enzyme is a phosphoribulokinase enzyme (EC 2.7.1.1) that is overexpressed in the genetically modified organism in an amount to achieve a phosphoribulokinase activity level that is higher than the native phosphoribulokinase activity level of the organism, and the second enzyme utilizes ribulose-5-phosphate to produce ribulose-1,5-bisphosphate.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 90.0
- Lexical Diversity: 1.64062
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15115670', '14187465', '15336744', '14853946', '14211415']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.609040469921158
- 35 USC 102 Novelty (BERT): 0.5906782102317346
- Combined Prediction Score: 0.6072042439522156
- Mean Citation Score: 322.9536480000001
- Max Citation Score: 520.89703
- Similarity Product: 456.89039215207686

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test