PATENT CLAIM ANALYSIS

Application Number: 16391583
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["424", "468000"]

Abstract:
Provided herein is a method of treating or preventing a disease or disorder (e.g., MS) in a subject in need thereof; comprising (a) administering to the subject a first dose of a pharmaceutical composition comprising a fumarate agent (e.g., DIVEF) for a first dosing period; (b) administering a vaccine; and (c) administering to the subject a second dose of the pharmaceutical composition for a second dosing period.

Claim (Index 99):
A method of treating multiple sclerosis in a human subject in need thereof, said method comprising:\n (a) administering to the subject a first dose of a pharmaceutical composition for a first dosing period, wherein the pharmaceutical composition comprises a fumarate agent selected from the group consisting of monomethyl fumarate, a pharmaceutically acceptable salt of monomethyl fumarate, dimethyl fumarate, and a combination thereof; (b) administering a vaccine to the subject, wherein the subject receives the vaccine during the first dosing period; and (c) administering to the subject a second dose of the pharmaceutical composition for a second dosing period, wherein: (i) the second dosing period is after the first dosing period, and (ii) the second dosing period is initiated within one day of the end of the first dosing period; wherein the second dose is the same as the first dose, and the first dose and the second dose are administered daily; wherein the multiple sclerosis is a relapsing form of multiple sclerosis; wherein the first dose is a therapeutically effective amount of monomethyl fumarate, a pharmaceutically acceptable salt of monomethyl fumarate, dimethyl fumarate, or a combination thereof; and wherein the vaccine induces (a) a T cell-dependent anamnestic humoral immune response, (b) a T cell-dependent neoantigen immune response, or (c) a T cell-independent immune response.

Metadata:
- Claim Count in Document: 86.0
- Percentile: 100.0
- Lexical Diversity: 2.02439
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15125612', '15686352', '15386175', '11800860', '15436032']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6976475816208846
- 35 USC 102 Novelty (BERT): 0.5858901133628206
- Combined Prediction Score: 0.6864718347950781
- Mean Citation Score: 265.853078
- Max Citation Score: 493.21973
- Similarity Product: 446.7942309936643

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test