PATENT CLAIM ANALYSIS

Application Number: 15755797
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["514", "235800"]

Abstract:
The present disclosure pertains to a pharmaceutical combination comprising (a) an alpha-isoform specific PI3K inhibitor, (b) an MDM2 inhibitor, and optionally (c) a BCL-2 inhibitor; combined preparations and pharmaceutical compositions thereof; the uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer a subject in need thereof comprising administering a therapeutically effective amount of such combination.

Claim (Index 52):
The method according to  claim 49  or  51 , wherein the cancer is selected from the group consisting of a benign or malignant tumor of the lung, bronchus, prostate, breast, pancreas, gastrointestine, colon, rectum, colon carcinoma, colorectal cancer, thyroid, liver, biliary tract, intrahepatic bile duct, hepatocellular, adrenal gland, stomach, gastric, glioma, glioblastoma, endometrial, melanoma, kidney, renal pelvis, bladder, uterus, cervix, vagina, ovary, multiple myeloma, esophagus, neck or head, brain, oral cavity and pharynx, larynx, small intestine, melanoma, villous colon adenoma, a sarcoma, a neoplasia, a neoplasia of epithelial character, a mammary carcinoma, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, polycythemia vera, essential thrombocythemia, a leukemia, a lymphoma, myelofibrosis with myeloid metaplasia, and Waldenstroem disease.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 88.0
- Lexical Diversity: 1.61702
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15755122', '15755140', '13799076', '15861555', '14429367']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.818419940457529
- 35 USC 102 Novelty (BERT): 0.5237849099162741
- Combined Prediction Score: 0.7889564374034035
- Mean Citation Score: 292.86425
- Max Citation Score: 317.25934
- Similarity Product: 185.4943843775034

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test