PATENT CLAIM ANALYSIS

Application Number: 16377752
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-10
Patent Classification: ["544", "284000"]

Abstract:
This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

Claim (Index 1):
A method of treating a viral infection in which the modulation of TLR7 and/or TLR 8 is involved in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1  is selected from the group consisting of: R 2  is selected from the group consisting of hydrogen, \u2014O\u2014(C 1-3 )-alkyl, halogen, (C 1-3 )-alkyl, \u2014O\u2014(C 1-3 )-alkyl-O\u2014(C 1-3 )-alkyl and CH 2 OH; R 3  is selected from the group consisting of hydrogen, \u2014O\u2014(C 1-3 )-alkyl, halogen, (C 1-3 )-alkyl and \u2014C(\u2550O)\u2014R 7 , wherein R 7  is selected from the group consisting of \u2014O\u2014(C 1-3 )-alkyl, NH 2 , NH(CH 3 ), N(CH 3 ) 2 , N(CH 3 )(C 1-3 )-alkyl, N((C 1-3 )-alkyl) 2  and pyrolidine; R 4  is hydrogen or fluorine; R 5  is selected from the group consisting of (C 1-3 )-alkyl, (C 1-3 )-fluoro-alkyl, and CH 2 OH; R 8 , R 9 , R 10 , R 11  and R 12  are each independently selected from the group consisting of hydrogen, (C 1-3 )-alkyl, \u2014O\u2014(C 1-3 )-alkyl and halogen; and R 13  is selected from the group consisting of hydrogen, (C 1-3 )-alkyl and (C 1-3 )-fluoro-alkyl.

Metadata:
- Claim Count in Document: 63.0
- Percentile: 100.0
- Lexical Diversity: 1.13636
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15591473', '14443305', '15420055', '14892701', '15333947']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7437061890574644
- 35 USC 102 Novelty (BERT): 0.5432692217370452
- Combined Prediction Score: 0.7236624923254225
- Mean Citation Score: 321.457294
- Max Citation Score: 387.09692
- Similarity Product: 347.4970249885941

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test