PATENT CLAIM ANALYSIS

Application Number: 16143788
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "210000"]

Abstract:
The present invention relates to novel compounds that inhibit Lp-PLA 2  activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA 2 , for example Alzheimer's disease.

Claim (Index 12):
The compound or a pharmaceutically acceptable salt thereof according to  claim 11 , wherein\n R 1  and R 2  together with the nitrogen and carbon to which they are attached form a 6-membered saturated, unsubstituted ring, which ring contains one additional heteroatom ring member selected from N, O and C(O); and R 3  is H; R 4  is H; X is O; n is 1 or 2; and A is wherein\n R 5  and R 9  are independently H or halo, \n Z\u2032 is N or CR 6 , \n Z is N or CR 8 ,\n wherein R 6  and R 8  are independently selected from the group consisting of H, CN, halo, C 1-3 alkyl, C 1-3 haloalkyl, \u2014S(O) 2 \u2014C 1-3 alkyl and \u2014S(O)\u2014C 1-3 alkyl, and \n \n V is CR 7 , wherein R 7  is -Q-(CH 2 ) m \u2014W, wherein\n Q is O, N, or CH 2 , \n m is 0 or 1, and \n W is 6 membered heteroaryl, wherein said heteroaryl is optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 haloalkyl, CN, halo and C 1-5  alkyl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.32353
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15327706', '14761636', '14234680', '14234687', '14569970']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8472752583219065
- 35 USC 102 Novelty (BERT): 0.5710715303250948
- Combined Prediction Score: 0.8196548855222253
- Mean Citation Score: 381.661348
- Max Citation Score: 451.69055
- Similarity Product: 440.9907075157464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test