PATENT CLAIM ANALYSIS

Application Number: 15764264
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["546", "209000"]

Abstract:
Problem to be Solved There is a need for a new antibiotic having a novel mechanism of action which exhibit strong antibacterial activity not only against sensitive bacteria but also against resistant bacteria thereof, and at the same time possesses excellent solubility an a safety profile amenable to human use. Solution to the Problem As a result of intensive research, the present inventors have found that a compound represented by general formula (I), a stereoisomer, or a pharmaceutically acceptable salt thereof inhibits DNA gyrase GyrB subunit and/or topoisomerase IV ParE subunit possesses excellent solubility and a safety profile for use in humans for the treatment of bacterial infectious diseases.

Claim (Index 5):
The compound according to  claim 4 , wherein 4-chloro-5-ethyl-N-{(3S,4R)-1-[5-hydroxy-1-methylethyl)-1,3,4-thiadiazol-2-yl]-3-methoxypiperidin-4-yl}-1H-imidazole-2-carboxamide is selected from Form I, or Form IL characterized by powder x-ray diffraction (XRD) spectrum (CuK, \u03bb=1.54 \u212b), wherein Form I has characteristic peaks 2\u03b8 (d) at 8.38 (10.54), 10.90 (8.11), 14.50 (6.08), 14.94 (5.92), 19.82 (4.48), and 24.68 (3.60), and wherein Form II has characteristic peaks 2\u03b8 (d) at 13.20 (6.67), 14.94 (5.92), 16.08 (5.51), 17.76 (4.99), 19.46 (4.56), and 24.82 (3.58).

Metadata:
- Claim Count in Document: 36.0
- Percentile: 90.0
- Lexical Diversity: 1.39286
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15547776', '15262112', '12187115', '11884923', '15314562']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8193582681956577
- 35 USC 102 Novelty (BERT): 0.5133839678874981
- Combined Prediction Score: 0.7887608381648418
- Mean Citation Score: 296.5449680000001
- Max Citation Score: 311.3937
- Similarity Product: 232.7325659103692

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test