PATENT CLAIM ANALYSIS

Application Number: 15994493
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "538000"]

Abstract:
Herein described are deuterated catecholamine derivatives of the general Formula I wherein, R 1  is deuterium, R 2 , and R 3  are independently selected from hydrogen and deuterium and wherein at least one of R 2  and R 3  has a deuterium enrichment in the range from 0.02 mol % to 100 mol % deuterium, and wherein the deuterium enrichment of R 2  and R 3  is different from each other and that the difference between the deuterium enrichment of R 2  and R 3  is at least 5 percentage points, R 4  is hydrogen, deuterium, C 1  to C 6 -alkyl or C 5  to C 6 -cycloalkyl, deuterated C 1  to C 6 -alkyl or C 5  to C 6 -cycloalkyl, or a group that is easily hydrolytically or enzymatically cleavable under physiological conditions, as well as their physiologically acceptable salts and their stereoisomers, enantiomers or diastereomers in optically pure form. The compounds can easily be prepared by mixing deuterated and non-deuterated compounds in a predefined ratio. The compounds show anti-Parkinson effect at lower doses and show lower side effects.

Claim (Index 1):
A pharmaceutical composition comprising\n L-2-amino-2,3,3-trideutero-3-(3,4-dihydroxyphenyl) propionic acid, or a physiologically acceptable salt thereof, having a deuterium enrichment above the natural abundance of deuterium; and L-2-amino-2,3-dideutero-3-(3,4-dihydroxyphenyl) propionic acid, or a physiologically acceptable salt thereof, having a deuterium enrichment above the natural abundance of deuterium.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 2.17778
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14765430', '15402343', '12224120', '10539845', '12941971']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7202915266519483
- 35 USC 102 Novelty (BERT): 0.6506649388834912
- Combined Prediction Score: 0.7133288678751026
- Mean Citation Score: 389.087596
- Max Citation Score: 601.24896
- Similarity Product: 597.1810401080131

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test