PATENT CLAIM ANALYSIS

Application Number: 16100816
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["210", "656000"]

Abstract:
The present invention discloses methods of regenerating apatite surfaces, for example after purification of a target analyte.

Claim (Index 1):
A method of purifying a target analyte with an apatite solid surface, the method comprising:\n (a) contacting the apatite solid surface with the target analyte, thereby separating the target analyte from one or more contaminants; (b) collecting the target analyte; and (c) after the collecting and before subsequent loading of additional target analyte, regenerating the apatite solid surface, the regenerating comprising: (i) contacting the apatite solid surface with a buffered calcium solution comprising a calcium ion at a concentration of at least 5 mM and a zwitterionic buffer, wherein the ratio of zwitterionic buffer concentration to calcium ion concentration is at least 2, and the pH of the buffered calcium solution is at least 5; (ii) after (i), contacting the apatite solid surface with a phosphate buffered solution at a pH of at least 6.5; and (iii) after (ii), contacting the apatite solid surface with a solution comprising an hydroxide.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 96.0
- Lexical Diversity: 1.05556
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14747162', '14747221', '14747181', '15719958', '13891502']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8290042756711099
- 35 USC 102 Novelty (BERT): 0.5973600875918124
- Combined Prediction Score: 0.8058398568631802
- Mean Citation Score: 420.717926
- Max Citation Score: 536.9121
- Similarity Product: 485.88194533685447

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test