PATENT CLAIM ANALYSIS

Application Number: 16104561
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "234500"]

Abstract:
The present invention relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.

Claim (Index 1):
A compound of structural Formula (I): or a salt thereof, wherein:\n R 1  is a 4- to 10-membered heterocycloalkyl and is optionally substituted with one or more R 4  groups; \n R 2  is a 5- to 10-membered heteroaryl, and is optionally substituted with one or more R 5  groups; \n R 3  is selected from H, C 1-6 alkyl, and C 1-6 haloalkyl; \n each R 4  is independently selected from halogen, cyano, hydroxy, alkyl, C 3-7 cycloalkyl, haloalkyl, hydroxyalkyl, (C 3-7 cycloalkyl)alkyl, (5- to 10-membered heterocycloalkyl)alkyl, (alkoxy)alkyl, alkoxy, haloalkoxy, hydroxyalkoxy, (C 3-7 cycloalkyl)alkoxy, (5- to 10-membered heterocycloalkyl)alkoxy, (alkoxy)alkoxy, C 3-7 cycloalkyl, C 3-7 halocycloalkyl, C 3-7 hydroxycycloalkyl, (alkoxy)C 3-7 cycloalkyl, 5- to 10-membered heterocycloalkyl, (halo)5- to 10-membered heterocycloalkyl, (hydroxy)5- to 10-membered heterocycloalkyl, (alkoxy)5- to 10-membered heterocycloalkyl, NR 7 R 8 , C(O)R 6 , C(O)OR 6 , C(O)NR 7 R 8 , NR 7 C(O)NR 7 R 8 , NR 7 C(O)OR 6 , NR 7 C(O)R 6 , S(O)R 6 , S(O) 2 R 6 , S(NR 7 )R 8 , S(O)(NR 7 )R 8 , SO 2 NR 7 R 8 , oxo, and \u2550NR 10 ; \n each R 5  is independently selected from amino, fluoro, chloro, cyano, C 1-3 alkyl, C 1-3 aminoalkyl, C 1-3 haloalkyl, C 1-3 alkoxy, C 1-3 hydroxyalkyl, C 1-3 haloalkoxy, C 3-7 cycloalkyl, and 5- to 10-membered heterocycloalkyl; \n each R 6 , R 7 , and R 8  is independently selected from H, C 1-3 alkyl, C 3-7 cycloalkyl, C 1-3 hydroxyalkyl, (C 1-3 alkoxy)C 1-3 alkyl, (C 3-7 cycloalkyl)C 1-3 alkyl, and 5- to 10-membered heterocycloalkyl and is optionally substituted with one or more R 9 ; \n R 7  and R 8 , together with the nitrogen to which they are both attached, optionally form a 5- to 10-membered heterocycloalkyl ring containing one or two heteroatoms; \n each R 6 , R 7 , or R 8  can form a ring with R 4 ; \n each R 9  is independently selected from halo, hydroxy, C 1-3 alkyl, C 1-3 haloalkyl, C 3-7 cycloalkyl, 5- to 10-membered heterocycloalkyl, and C 1-3 alkoxy; and \n each R 10  is independently selected from H, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 haloalkyl, C 3-7 cycloalkyl, and 5- to 10-membered heterocycloalkyl.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 96.0
- Lexical Diversity: 1.04
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16035310', '15990283', '13655164', '15486017', '13547314']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7642712111797482
- 35 USC 102 Novelty (BERT): 0.5707033183044381
- Combined Prediction Score: 0.7449144218922172
- Mean Citation Score: 330.5083120000001
- Max Citation Score: 447.91846
- Similarity Product: 367.3892201727247

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test