PATENT CLAIM ANALYSIS

Application Number: 15768025
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "210210"]

Abstract:
The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.

Claim (Index 2):
Compounds for the use according to  claim 1 , wherein\n R 1  and R 2  are the same or different and are independently selected from the group consisting of\n hydrogen, \n optionally substituted alkyl, or \n R 1  and R 2  together with the nitrogen atom to which they are bonded form an optionally substituted 3 to 6-membered ring, which may optionally contain further heteroatoms; \n Z is a cyclic group or a linear group and is selected from\n optionally substituted 5- or 6-membered heteroaryl \n optionally substituted aryl, \n optionally substituted 5- or 6-membered heterocyclyl, \n amino (\u2014NH\u2014), \n an alkylaminocarbonyl group [\u2014(CH 2 )\u2014NH\u2014(C\u2550O)\u2014], or \n an alkylcarbonylamino group [\u2014(CH 2 )\u2014(C\u2550O)\u2014NH\u2014]; \n A 1  is optionally substituted alkanediyl; A 2  is\n optionally substituted alkanediyl, or \n a direct bond; \n R 3  is\n hydrogen, or \n C 1 -C 3 -alkyl; or \n A 1  and R 3  together with the nitrogen atom to which they are bonded form an optionally substituted 4-membered monocyclic ring; or R 3  and A 2  together with the nitrogen atom to which they are bonded form an optionally substituted 4- to 7-membered aliphatic ring; and Ar is optionally substituted bicyclic heteroaryl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.25532
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15769148', '14310254', '15517528', '14007533', '15185186']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8112060568123389
- 35 USC 102 Novelty (BERT): 0.5531679993425641
- Combined Prediction Score: 0.7854022510653614
- Mean Citation Score: 298.633386
- Max Citation Score: 422.5474
- Similarity Product: 356.134190527296

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test