PATENT CLAIM ANALYSIS

Application Number: 16254739
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-08
Patent Classification: ["435", "184000"]

Abstract:
The present invention provides a method for inhibiting chondroitinase activity in a substrate by introducing a non-substrate glycosaminoglycan (GAG) to the substrate containing the chondroitinase. The non-substrate GAG is undegradable by chondroitinase. The GAG may be administered as a single dose or in multiple doses. The chondroitinase may be Chondroitinase B, Chondroitinase C, Chondroitinase AC, or Chondroitinase ABC. The substrate may be one or more of dermatan sulfate, hyaluronic acid, chondroitin sulfate, or derivatives thereof. The non-substrate GAG may be from naturally unbranched homo-polysaccharide, unnaturally branched GAG, or a hybrid GAG molecule fused of two or three GAG chains, being produced by chemical synthesis or enzymatic reaction. The non-substrate GAG may be heparin, heparan sulfate, and keratan sulfate. The non-substrate GAG may bind to the active residue of the chondroitinase when being introduced to the substrate such that the chondroitinase is no longer enzymatically active.

Claim (Index 7):
The method of  claim 2 , wherein said chondroitinase is originated from  Proteus vulgaris.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 99.0
- Lexical Diversity: 2.02439
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10373669', '13000721', '11638318', '11638094', '11078915']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6283665420666813
- 35 USC 102 Novelty (BERT): 0.5309263114676722
- Combined Prediction Score: 0.6186225190067804
- Mean Citation Score: 313.71971599999995
- Max Citation Score: 340.58398
- Similarity Product: 225.313854809531

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test