PATENT CLAIM ANALYSIS

Application Number: 16113611
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["544", "180000"]

Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, ester, stereoisomer, tautomer, solvate, hydrate, or combination thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

Claim (Index 9):
The compound of  claim 1 , selected from the compounds set forth below or a pharmaceutically acceptable salt thereof: Com- pound Structure 1   2   3   4   5   6   7   8   9   10   11   12   13   14   15   16

Metadata:
- Claim Count in Document: 8.0
- Percentile: 96.0
- Lexical Diversity: 1.84416
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15979128', '15988806', '15988783', '15988763', '15597431']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8239721109333473
- 35 USC 102 Novelty (BERT): 0.5327893254693097
- Combined Prediction Score: 0.7948538323869435
- Mean Citation Score: 346.565066
- Max Citation Score: 375.6885
- Similarity Product: 325.6611941909194

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test