PATENT CLAIM ANALYSIS

Application Number: 16322312
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-06
Patent Classification: ["424", "450000"]

Abstract:
The present invention provides a way to capture a biomolecule such as a protein in one or more layers of covalently bonded amorphous silica, forming a cage or shell which preserves the shape of the protein and prevents denaturation caused by heat and/or aging and/or non-physiological conditions, through unfolding and loss of secondary and/or higher order structure.

Claim (Index 39):
A method of reducing biomolecule denaturation in non-physiological conditions comprising enveloping the biomolecule with silica, the enveloping comprising contacting a hydrolysed silica precursor with an aqueous solution comprising the biomolecule, wherein the silica precursor precipitates about the biomolecule; or\n a method of transporting and/or storing a biomolecule, comprising a) obtaining the biomolecule enveloped with silica b) transporting the biomolecule from a first location to a second location and/or storing the biomolecule, wherein at least a portion of the transporting and/or storing occurs in the absence of a cold-chain; or a method of providing a gastric resistant coating to a biomolecule comprising contacting a hydrolysed silica precursor with an aqueous solution comprising the biomolecule, wherein the silica precursor precipitates about the biomolecule to form the gastric resistant coat.

Metadata:
- Claim Count in Document: 75.0
- Percentile: 99.0
- Lexical Diversity: 1.25
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10814123', '14111305', '14650645', '11721728', '14374388']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6795956494486513
- 35 USC 102 Novelty (BERT): 0.4866444137936351
- Combined Prediction Score: 0.6603005258831497
- Mean Citation Score: 131.735926
- Max Citation Score: 144.53966
- Similarity Product: 90.76401732449057

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test