PATENT CLAIM ANALYSIS

Application Number: 16052307
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-04
Patent Classification: ["540", "478000"]

Abstract:
A vinca alkaloid compound substituted at the 20′-position with a carboxamido group is disclosed. The carbonyl of the carboxamido group is bonded to a 20′-amino group and to a ring system that contains up to three 5-, 6- or 7-membered rings that are fused or otherwise bonded together. Each ring can be carbocyclic or heterocyclic, with a heterocyclic ring containing up to three hetero ring atoms that are the same or different and are selected from nitrogen, oxygen and sulfur. The ring system can include up to four substituent groups other than hydrogen that are discussed within. Methods of preparing the compounds are disclosed as are compositions for their use and methods of treatment using d compound. A particularly preferred compound has an activity in specified cancer cell growth inhibition assays that is the same or better than its parental, unsubstituted vinca compound and is not subject to Pgp-mediated efflux.

Claim (Index 3):
The 20\u2032-amide-substituted vinca alkaloid compound or pharmaceutically acceptable salt thereof according to  claim 2 , wherein said ring system contains one aromatic ring.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 96.0
- Lexical Diversity: 1.70213
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14648624', '13580340', '12594495', '11003560', '15298950']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7298381618211853
- 35 USC 102 Novelty (BERT): 0.6110587110053909
- Combined Prediction Score: 0.717960216739606
- Mean Citation Score: 382.103808
- Max Citation Score: 565.6980599999998
- Similarity Product: 476.1853593391977

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test