PATENT CLAIM ANALYSIS

Application Number: 15772550
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-03
Patent Classification: ["514", "052000"]

Abstract:
Provided herein are compounds of Formula (I): or a pharmaceutically acceptable salt thereof, and compositions comprising such compounds that are useful for increasing the amount of NAD+ in cells. Also disclosed are methods of using the disclosed compounds and compositions for treating mitochondrial-related diseases or disorders.

Claim (Index 1):
A compound of Formula (I): or a pharmaceutically acceptable salt thereof;\n wherein: \n B is \n \u2003wherein X \u2212  is a counteranion; R 1  is phenyl optionally substituted with one or more substituents selected from halogen, hydroxyl, nitro, cyano, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 3 -C 6 -cycloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, \u2014N(R 1a ) 2 , C 1 -C 6 -acylamino, \u2014COR 1b , \u2014OCOR 1b , \u2014NHCOR 1b , \u2014NHSO 2 (C 1 -C 6 -alkyl), \u2014SO 2 N(R 1a ) 2 , and \u2014SO 2 (C 1 -C 6 -alkyl), wherein each R 1a  is independently selected from hydrogen and C 1 -C 6 -alkyl, and R 1b  is hydroxyl, C 1 -C 6 -alkoxy, NH 2 , NH(C 1 -C 6 -alkyl), or N(C 1 -C 6 -alkyl) 2 ; R 2  is hydrogen or C 1 -C 6 -alkyl; R 3a  and R 3b  are independently hydrogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, benzyl, indolyl, or imidazolyl, wherein C 1 -C 6 -alkyl and C 1 -C 6 -alkoxy can be is optionally substituted with one or more of halogen, amino, amido, guanidyl, hydroxyl, thiol, or carboxyl, and benzyl is optionally substituted with one or more halogen or hydroxyl; or R 3a  and R 3b  is taken together with the carbon atom to which they are attached to form a C 3 -C 6  cycloalkyl group optionally substituted with one or more halogen, amino, amido, guanidyl, hydroxyl, thiol, and carboxyl; and R 4  is hydrogen, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, or C 3 -C 6 -cycloalkyl.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 93.0
- Lexical Diversity: 1.33333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15766455', '15517893', '14776683', '13837872', '14776688']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7833245043889919
- 35 USC 102 Novelty (BERT): 0.5387938707696663
- Combined Prediction Score: 0.7588714410270594
- Mean Citation Score: 299.075464
- Max Citation Score: 377.4746
- Similarity Product: 314.8803209119081

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test