PATENT CLAIM ANALYSIS

Application Number: 16055396
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["514", "243000"]

Abstract:
The present invention relates to substituted pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.

Claim (Index 31):
A method for treating a disease caused by and/or associated with a dysregulated protein kinase activity which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I): wherein: Ring W is a pyrrole; R1 is a substituted aryl; R2 is CONR6R7 wherein R6 and R7 are independently hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6  alkyl, straight or branched C 2 -C 6  alkenyl, straight or branched C 2 -C 6  alkynyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl, heteroaryl-alkyl, heterocyclyl and heterocyclyl-alkyl, or R6 and R7, taken together with the nitrogen atom to which they are bonded, may form an optionally substituted 5 to 7 membered heterocyclyl group optionally containing one additional heteroatom selected from N, O and S; R3 is hydrogen, halo or an optionally substituted group selected from straight or branched C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, heterocyclyl and heterocyclyl-alkyl; R4 is an optionally substituted group wherein:\n R8 is hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6  alkyl, straight or branched C 2 -C 6  alkenyl, straight or branched C 2 -C 6  alkynyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl, heteroaryl-alkyl, heterocyclyl and heterocyclyl-alkyl, COR9, CONR10R11 and SO 2 R12,\n wherein: \n R9 is a group optionally substituted selected from straight or branched C 1 -C 6  alkyl, straight or branched C 2 -C 6  alkenyl, straight or branched C 2 -C 6  alkynyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl, heteroaryl-alkyl, heterocyclyl and heterocyclyl-alkyl; \n R10 and R11 are independently hydrogen or an optionally substituted group selected from straight or branched C 1 -C 6  alkyl, straight or branched C 2 -C 6  alkenyl, straight or branched C 2 -C 6  alkynyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl, heteroaryl-alkyl, heterocyclyl and heterocyclyl-alkyl, or R10 and R11, taken together with the nitrogen atom to which they are bonded, may form an optionally substituted 5 to 7 membered heterocyclyl group optionally containing one additional heteroatom selected from N, O and S; \n R12 is a group optionally substituted selected from straight or branched C 1 -C 6  alkyl, straight or branched C 2 -C 6  alkenyl, straight or branched C 2 -C 6  alkynyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl, heteroaryl-alkyl, heterocyclyl and heterocyclyl-alkyl; \n \n R5 is hydrogen, halo or an optionally substituted group selected from straight or branched C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, cycloalkyl-alkyl, heterocyclyl and heterocyclyl-alkyl; or the pharmaceutically acceptable salts thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.48889
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15599025', '14418555', '15598976', '14235477', '14112559']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8643866618394344
- 35 USC 102 Novelty (BERT): 0.6139116518876939
- Combined Prediction Score: 0.8393391608442603
- Mean Citation Score: 546.5052059999998
- Max Citation Score: 636.0981
- Similarity Product: 478.9846503971637

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test