PATENT CLAIM ANALYSIS

Application Number: 15741786
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "154000"]

Abstract:
The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.

Claim (Index 10):
A pharmaceutical formulation according to  claim 9  wherein the antimalarial agent is selected from artemisinin or an artemisinin and its derivatives (such as artemether or dihydroartemisinin, chloroquine, quinine, mefloquine, amodiaquine, atovaquone/proguanil, doxycycline, lumefantrine, piperaquine, pyronaridine, halofantrine, pyrimethamine-sulfadoxine, primaquine, quinacrine, doxycycline, atovaquone, proguanil hydrochloride, piperaquine, ferroquine, tafenoquine, arterolane, Spiro[3H-indole-3,1\u2032-[1H]pyrido[3,4-b]indol]-2(1H)-one, 5,7\u2032-dichloro-6\u2032-fluoro-2\u2032,3\u2032,4\u2032,9\u2032-tetrahydro-3\u2032-methyl-, (1\u2032R, 3\u2032S)-(CAS Registry Number: 1193314-23-6), Sulfur, [4-[[2-(1,1-difluoroethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]am ino]phenyl] pentafluoro-] (CAS Registry Number: 1282041-94-4), Morpholine,4-[2-(4-cis-dispiro [cyclohexane-1,3\u2032-[1,2,4]trioxolane-5\u2032,2\u2033-tricyclo[3.3.1.1 3,7 ]decan]-4-ylphenoxy)ethyl]-(CAS Registry Number: 1029939-86-3), [3,3\u2032-Bipyridin]-2-amine, 5-[4-(methylsulfonyl)phenyl]-6\u2032-(trifluoromethyl)-(CAS Registry Number: 1314883-11-8), Ethanone, 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydroimidazo [1,2-a]pyrazin-7(8H)-yl]-(CAS Registry Number 1261109-90-3).

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.63333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14379332', '14905369', '12833909', '13912898', '14978059']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7400827581335131
- 35 USC 102 Novelty (BERT): 0.5210272567678181
- Combined Prediction Score: 0.7181772079969435
- Mean Citation Score: 233.309988
- Max Citation Score: 302.61624
- Similarity Product: 238.9882293940973

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test