PATENT CLAIM ANALYSIS

Application Number: 15755390
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "217010"]

Abstract:
The present invention provides novel means and methods for treatment auf immunemediated inflammatory diseases.

Claim (Index 1):
Compounds according to the general formula (I) for use in a method of therapeutic and/or prophylactic treatment of immune-mediated inflammatory diseases wherein: R 1  is selected from the group comprising hydrogen; linear or branched C 1 -C 8 -alkyl; C 2 -C 8 -alkenyl; C 3 -C 8 -cycloalkyl; C 8 -C 10 -aryl; C 4 -C 10 -cycloalkylalkyl wherein the cycloalkyl group has 3 to 6 carbon atoms and the alkyl group has 1 to 4 carbon atoms; and/or C 7 -C 14 -arylalkyl wherein the aryl group has 6 to 10 carbon atoms and the alkyl group has 1 to 4 carbon atoms; R 2  is selected from the group comprising hydrogen; linear or branched C 1 -C 8 -alkyl; C 2 -C 8 -alkenyl; C 3 -C 8 -cycloalkyl; C 8 -C 10 -aryl; C 4 -C 10 -cycloalkylalkyl wherein the cycloalkyl group has 3 to 6 carbon atoms and the alkyl group has 1 to 4 carbon atoms; C 7 -C 14 -arylalkyl wherein the aryl group has 6 to 10 carbon atoms and the alkyl group has 1 to 4 carbon atoms; R 3  is selected from the group comprising hydrogen; linear or branched C 1 -C 8 -alkyl; C 2 -C 8 -alkenyl; C 3 -C 8 -cycloalkyl; C 8 -C 10 -aryl; C 4 -C 10 -cycloalkylalkyl wherein the cycloalkyl group has 3 to 6 carbon atoms and the alkyl group has 1 to 4 carbon atoms; C 7 -C 14 -arylalkyl wherein the aryl group has 6 to 10 carbon atoms and the alkyl group has 1 to 4 carbon atoms; linear or branched alkyl groups of the type \u2014C n H 2n \u2014U-D wherein n is 1 , 2, 3 or 4, U is selected from the group comprising O, CO, COO, CONH, S, guanidine and/or NH and D is selected from the group comprising H and/or C 1 -C 3 -alkyl; \u2014CH 2 -C 6 H 4 \u2014X wherein X is selected from the group comprising OH, SH, C 1 -C 3 -alkyl and/or NH 2 ; \u2014CH 2 -imidazole; \u2014CH 2 -indole; \u2014CH 2 -(furanyl-3-yl); \u2014CH 2 \u2014 (pyridyl-3-yl) and/or \u2014CH 2 -(imidazolyl-3-yl); or R 2  and R 3  together with the carbon atom to which they are attached form a 5- to 7-membered non aromatic carbocycle or heterocycle comprising from 1 to 3 hetero atoms selected from the group comprising O, N and/or S; R 4  is selected from the group comprising hydrogen; C 1 -C 10 -alkyl; \u2014W and/or \u2014Y\u2014Z; Y is selected from the group comprising C 1 -C 6 -alkyl; C 2 -C 6 -alkenyl; C 2 -C 6 -alkynyl, C 3 -C 6 -cycloalkyl; C 4 -C 10 -cycloalkylalkyl wherein the cycloalkyl group has 3 to 6 carbon atoms and the alkyl group has 1 to 4 carbon atoms; C 6 -C 10 -aryl; C 7 -C 14 -arylalkyl wherein the aryl group has 6 to 10 carbon atoms and the alkyl group has 1 to 4 carbon atoms; C 1 -C 6 -alkyl comprising at least one moiety independently selected from the group comprising oxygen, sulphur, SO, SO 2 , CO, NH, N(C 1 -C 3 -alkyl) and/or T; a 3- to 6-membered aromatic or non aromatic carbocycle or heterocycle containing at least one of O, N or S as heteroatoms; and/or a structural element comprising a 3- to 6-membered aromatic or non aromatic carbocycle or heterocycle comprising from 1 to 3 heteroatoms selected from the group comprising O, N and/or S and a group selected from the group comprising oxygen, sulphur, SO, SO 2 , CO, NH, N(C 1 -C 3 -alkyl) and/or C 1 -C 6 -alkyl comprising at least one moiety independently selected from the group comprising oxygen, sulphur, SO, SO 2 , CO, NH and/or N(C 1 -C 3 -alkyl); T is selected from the group comprising W is selected from the group comprising Z is selected from the group comprising mono-, bi- or tricyclic aromatic or non aromatic carbocycles or heterocycles comprising from 1 to 3 heteroatoms selected from the group comprising O, N and/or S, wherein the carbocycle or heterocycle optionally is substituted by at least one group selected from the group comprising halogen, cyano, OH, CF 3 , C 1 -C 4 -alkyloxy and/or C 1 C 6 -alkyl; or R 3  and R 4  together with the ring atoms to which they are attached form a 5- to 7-membered non aromatic heterocycle comprising from 1 to 3 heteroatoms selected from the group comprising O, N and/or S; and/or racemates, enantiomers, diastereomers, solvates, hydrates, and pharmaceutically acceptable salts and/or esters thereof.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11901843', '09886773', '12786221', '11801473', '13567146']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7501634210527826
- 35 USC 102 Novelty (BERT): 0.4911650529639698
- Combined Prediction Score: 0.7242635842439014
- Mean Citation Score: 226.707182
- Max Citation Score: 232.65176
- Similarity Product: 175.20622187119483

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test