PATENT CLAIM ANALYSIS

Application Number: 16062754
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["424", "204100"]

Abstract:
The present invention relates to thermally stable oral rotavirus vaccine formulations comprising one or more rotavirus reassortant or attenuated rotavirus strains, a pharmaceutically acceptable calcium salt, adipic acid, sucrose, and sodium phosphate, wherein each of the one or more rotavirus reassortant or attenuated rotavirus strain is stable for 7 days at 37° C., for 45 days at 25° C. and for 2 years or more at 2-8° C. The calcium containing formulations of the invention may further comprise one or more excipients which are present in an amount that is effective to optimize the calcium ions free in solution to stabilize the rotavirus particles. In embodiments of the invention, the formulation comprises a surfactant, such as polysorbate 80. The invention also relates to methods of using the rotavirus vaccine compositions of the invention to prevent rotavirus infection, or to reduce the likelihood of infection or to prevent, ameliorate, or delay the onset or progression of the clinical manifestations thereof.

Claim (Index 6):
The rotavirus vaccine formulation of  claim 5 , wherein the formulation comprises G1, G2, G3, G4, and P1A rotavirus reassortants.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 94.0
- Lexical Diversity: 1.92222
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15327142', '11816443', '15327102', '13486039', '14396691']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7314433116531613
- 35 USC 102 Novelty (BERT): 0.529831804653695
- Combined Prediction Score: 0.7112821609532147
- Mean Citation Score: 289.82165
- Max Citation Score: 319.52127
- Similarity Product: 213.21071120590568

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test