PATENT CLAIM ANALYSIS

Application Number: 15751169
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "133100"]

Abstract:
The present invention provides novel humanized anti-human CCR7 antibodies and compositions comprising such antibodies. The antibodies and compositions are useful in the treatment of a cancer of which the tumour cells express a CCR7 receptor, in the treatment of inflammatory conditions, conditions or complications arising from tissue or organ transplantations, and conditions or complications arising from or associated with fibrosis. The invention further provides nucleic acid molecules encoding the anti-CCR7 antibodies, cells expressing the anti-CCR7 antibodies and methods for producing the anti-CCR7 antibodies.

Claim (Index 17):
The humanized anti-CCR7 antibody according to claim  15 , wherein the heavy chain variable domain of the antibody comprises 4 heavy chain framework regions, HFR1 to HFR4, and 3 hypervariable regions HVR-H1 to HVR-H3 that are operably linked in the order HFR1, HVR-H1, HFR2, HVR-H2, HFR3, HVR-H3 and HFR4, wherein the light chain variable domain of the antibody comprises 4 light chain framework regions, LFR1 to LFR4, and 3 hypervariable regions HVR-L1 to HVR-L3 that are operably linked in the order LFR1, HVR-L1, LFR2, HVR-L2, LFR3, HVR-L3 and LFR4, wherein the heavy chain framework regions HFR1 to HFR4 have the amino acid sequences of:\n i) SEQ ID NO's: 40, 43, 45 and 48, respectively; ii) SEQ ID NO's: 41, 44, 46 and 49, respectively; or, iii) SEQ ID NO's: 42, 44, 47 and 49, respectively, and wherein the light chain framework regions LFR1 to LFR4 have the amino acid sequences of:\n iv) SEQ ID NO's: 50, 52, 55 and 58, respectively; or, \n v) SEQ ID NO's: 51, 53, 56 and 59, respectively.

Metadata:
- Claim Count in Document: 92.0
- Percentile: 88.0
- Lexical Diversity: 1.8
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15756043', '14673792', '15182327', '15399122', '15505064']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7315293562196948
- 35 USC 102 Novelty (BERT): 0.5454523119701062
- Combined Prediction Score: 0.712921651794736
- Mean Citation Score: 378.784036
- Max Citation Score: 384.58862
- Similarity Product: 291.9933795424223

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test