PATENT CLAIM ANALYSIS

Application Number: 15744054
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "019300"]

Abstract:
The present invention refers to new binding proteins based on di-ubiquitin modified in 12, 13, or 14 positions selected from positions R42, I44, H68, V70, R72, L73, R74, K82, L84, Q138, K139, E140, S141, and T142 of di-ubiquitin and being able to bind specifically with high affinity to selected targets. Furthermore, the invention provides a method for the generation of said binding proteins. In addition, libraries encoding for said binding proteins based on di-ubiquitin muteins modified in 12, 13, or 14 positions selected from R42, I44, H68, V70, R72, L73, R74, K82, L84, Q138, K139, E140, S141, and T142 are provided.

Claim (Index 19):
The binding protein of  claim 9 , wherein the binding protein has a specific binding affinity of at least 700 nM for the target.

Metadata:
- Claim Count in Document: 54.0
- Percentile: 86.0
- Lexical Diversity: 2.22951
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14126358', '13144809', '14442376', '12293715', '13514133']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7422447250910542
- 35 USC 102 Novelty (BERT): 0.5341474464707309
- Combined Prediction Score: 0.7214349972290219
- Mean Citation Score: 294.255452
- Max Citation Score: 307.40186
- Similarity Product: 168.36326209570527

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test