PATENT CLAIM ANALYSIS

Application Number: 15749377
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["546", "152000"]

Abstract:
Production of pitavastatin calcium safely on an industrial scale with a high yield and high selectivity at low cost. A method of producing pitavastatin calcium including step (i) for acetalizing a compound represented by the formula (1) to give a compound represented by the formula (3), step (ii) for reacting a compound represented by the formula (3) with an acid to give a compound represented by the formula (4), and step (iii) for hydrolyzing a compound represented by the formula (4) and reacting same with a calcium compound.

Claim (Index 4):
The production method according to  claim 2 , comprising\n (viii) a step of reacting a compound represented by the following formula (12): in the presence of a titanium catalyst with a compound represented by the following formula (13): wherein R is a straight chain alkyl group having a carbon number of 1-8 or a branched alkyl group having a carbon number of 3-8, to give a compound represented by the following formula (14): wherein R is as defined above; and\n (ix) a step of reacting said compound represented by the formula (14) obtained in step (viii) with an enzyme having an activity capable of stereoselectively reducing a carbonyl group, a microorganism or cell having an ability to produce the enzyme, a treated product of the microorganism or cell, and/or a culture solution containing the enzyme obtained by culturing the microorganism or cell to give a compound represented by the following formula (6): \n wherein R is as defined above.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 86.0
- Lexical Diversity: 2.34783
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15600196', '11666905', '15116861', '10553394', '13510375']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7722954214716372
- 35 USC 102 Novelty (BERT): 0.508931008506853
- Combined Prediction Score: 0.7459589801751588
- Mean Citation Score: 246.087964
- Max Citation Score: 269.67303
- Similarity Product: 169.83540266633034

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test