PATENT CLAIM ANALYSIS

Application Number: 16415319
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-09
Patent Classification: ["514", "230500"]

Abstract:
The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Claim (Index 32):
A compound selected from the group consisting of:\n 6-((((1R,3S,4R)-4-(((6-fluoro-3-methoxyquinoxalin-5-yl)methyl)amino)-3-hydroxycyclohexyl)amino)methyl)-2H-pyrazino[2,3-b][1,4]oxazin-3(4H)-one; 6-({[(1R,4R)-4-{[(3-methoxyquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,4R)-4-{[(6-fluoro-3-methoxyquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,4R)-4-[({6-fluoro-3-[(1E)-(hydroxyimino)methyl]quinoxalin-5-yl}methyl)amino]cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,4R)-4-{[(6-chloro-3-methoxyquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,3S,4R)-4-{[(6-fluoro-3-methoxyquinoxalin-5-yl)methyl]amino}-3-hydroxycyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,4R)-4-({[3-(2-aminoethoxy)-6-fluoroquinoxalin-5-yl]amino}methyl)cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,2S,4R)-4-{[(6-fluoro-3-methoxyquinoxalin-5-yl)methyl]amino}-2-hydroxycyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 7-fluoro-8-({[(1S,2R,4S)-2-hydroxy-4-[({3-oxo-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-6-yl}methyl)amino]cyclohexyl]amino}methyl)-1-methyl-1,2-dihydroquinoxalin-2-one; 6-({[(1R,4R)-4-{[(6-fluoroquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,4R)-4-[({7-chloro-2-methoxypyrido[2,3-b]pyrazin-8-yl}methyl)amino]cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1R,2S,4R)-4-{[(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)methyl]amino}-2-hydroxycyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]thiazin-3-one; 6-({[(1S,3R,4S)-4-{[(6-chloro-3-methoxyquinoxalin-5-yl)methyl]amino}-3-hydroxycyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]oxazin-3-one; 6-({[(1S,3R,4S)-4-{[(7-chloro-5-fluoro-2-methoxyquinolin-8-yl)methyl]amino}-3-hydroxycyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]oxazin-3-one; 6-({[(1R,4R)-4-{[(7-fluoro-2-methoxyquinolin-8-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]oxazin-3-one; 6-({[(1R,4R)-4-{[(6,8-difluoro-3-methoxyquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]oxazin-3-one; and 6-({[(1R,4R)-4-{[(6-chloro-3-methoxyquinoxalin-5-yl)methyl]amino}cyclohexyl]amino}methyl)-2H,3H,4H-pyrazino[2,3-b][1,4]oxazin-3-one; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 100.0
- Lexical Diversity: 1.03846
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12298326', '12809555', '10502233', '12520580', '12279329']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8140576031503426
- 35 USC 102 Novelty (BERT): 0.5452371608530503
- Combined Prediction Score: 0.7871755589206134
- Mean Citation Score: 366.715636
- Max Citation Score: 386.1195
- Similarity Product: 347.5242493325472

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test