PATENT CLAIM ANALYSIS

Application Number: 15901803
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["435", "006110"]

Abstract:
Methods are provided for monitoring a subject having a graft for an acute rejection (AR) response, e.g., to predict, to diagnose, and/or to characterize an AR response. In practicing the subject methods, the expression level of at least one gene in a sample from the subject, e.g., a blood or biopsy sample, is evaluated, e.g., at the nucleic acid and/or protein level, to monitor the subject. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods.

Claim (Index 19):
A kit for monitoring a subject who has received an allograft for an acute rejection (AR) response, said kit comprising:\n (a) a gene expression evaluation element for evaluating expression of at least one gene in a sample to obtain a gene expression result, wherein said at least one gene is selected from the group consisting of: NKTR, MAPK9, DUSP1, PBEF1 and PSEN1; and (b) a phenotype determination element for employing said gene expression result to predict the onset of an AR response, to diagnose an AR response, and/or to characterize an AR response in said subject, thereby monitoring said subject for an AR response.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 88.0
- Lexical Diversity: 1.75862
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13144047', '13635667', '11375681', '13512539', '10587569']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5596830642947069
- 35 USC 102 Novelty (BERT): 0.6898881444046397
- Combined Prediction Score: 0.5727035723057002
- Mean Citation Score: 408.94621
- Max Citation Score: 784.73627
- Similarity Product: 673.1498180995864

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test