PATENT CLAIM ANALYSIS

Application Number: 15780704
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "049000"]

Abstract:
Provided relates to pharmaceutically acceptable salts of conjugates including a chemotherapeutic drug and an amino acid or a derivative thereof, which are readily taken up by a target cell and reduce side effects induced by the chemotherapeutic drug. Further, the subject matter relates to pharmaceutically acceptable salts of conjugates comprising cytidine analog drugs and aspartic or glutamic acid and analogs thereof, pharmaceutical compositions including these conjugates and use thereof for the treatment of cancer or a pre-cancer condition or disorder.

Claim (Index 47):
A pharmaceutically acceptable salt of a compound, the salt represented by the structure of formula (I)\n A-D.Y\u2003\u2003(I) wherein, A denotes an amino acid selected from the group consisting of aspartic acid, glutamic acid, asparagine, glutamine, and derivatives and analogs thereof; D denotes a residue of a drug selected from the group consisting of a cytotoxic agent, a cytostatic agent and a chemotherapeutic agent, wherein D is attached to A through the side chain functional group of A; and Y is a pharmaceutically acceptable organic or inorganic acid or residue of an acid selected from the group consisting of acetic acid, hydrochloric acid, methanesulfonic acid, phosphoric acid, citric acid, lactic acid, succinic acid, tartaric acid, boric acid, benzoic acid, toluenesulfonic acid, benzenesulfonic acid, ascorbic acid, sulfuric acid, maleic acid, formic acid, malonic acid, nicotinic acid and oxalic acid.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 94.0
- Lexical Diversity: 1.57407
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11497511', '13164204', '14061261', '12933364', '11833959']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8099686553631318
- 35 USC 102 Novelty (BERT): 0.4909750902952449
- Combined Prediction Score: 0.7780692988563431
- Mean Citation Score: 239.09716
- Max Citation Score: 253.29366
- Similarity Product: 207.2004689465654

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test