PATENT CLAIM ANALYSIS

Application Number: 15988781
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "418000"]

Abstract:
The present invention relates to a novel oxindole derivative having anticancer activity, a preparation method thereof, and a method for treating cancer using the same. More specifically, the present invention relates to an oxindole derivative produced as a result of CH alkylation and subsequent intramolecular cyclization reaction using a rhodium (III) catalyst, a preparation method of the same, and a method for treating cancer containing the same as an active ingredient. The novel oxindole derivatives according to the present invention have excellent anticancer activity against various human cancer cell lines and are expected to be useful for the treatment of cancer. In addition, the preparation method of an oxindole derivative using the rhodium (III) catalyst of the present invention can be applied and introduced into a wide range of functional groups, and is a reaction having positional selectivity and chemical selectivity. As a reaction for synthesizing a new drug or a compound having biological activity, it will be useful.

Claim (Index 7):
The method of  claim 6 , wherein the acid additive in step (S2) is acetic acid, ammonium chloride (NH 4 Cl) or a mixture thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 2.14634
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14781901', '15569313', '15735468', '14382645', '15269267']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7503901066296375
- 35 USC 102 Novelty (BERT): 0.5269777004769102
- Combined Prediction Score: 0.7280488660143648
- Mean Citation Score: 267.997584
- Max Citation Score: 303.1045200000001
- Similarity Product: 203.49333934344293

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test