PATENT CLAIM ANALYSIS

Application Number: 15757633
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["435", "029000"]

Abstract:
The invention relates to the field of diagnosis of epithelial-to-mesenchymal transition (EMT), such as mesothelial-to-mesenchymal transition (MMT), in particular EMT of the peritoneum, which often occurs upon peritoneal dialysis. The invention provides a method and kit based on markers comprising at least one extracellular matrix protein, e.g., collagen 13, collagen 6, and/or keratin 34, at least one protein involved in building and/or restructuring of extracellular matrix, e.g., matrix metalloproteinase 1, at least one protein involved in cell-cell and/or cell-matrix contacts, e.g., cadherin 13 or thrombospondin 1, at least one growth factor, e.g., VEGF, and, optionally, at least one BMP antagonist, e.g., Gremlin 1.

Claim (Index 15):
A method for predicting the progression of epithelial-to-mesenchymal transition of a tissue, preferably, the peritoneum, of a patient, comprising analyzing the status of the tissue of the patient with a kit of  claim 1 .

Metadata:
- Claim Count in Document: 22.0
- Percentile: 90.0
- Lexical Diversity: 1.91176
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13289097', '14346693', '13829163', '13482568', '14353665']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.566167707538217
- 35 USC 102 Novelty (BERT): 0.4862098040301605
- Combined Prediction Score: 0.5581719171874114
- Mean Citation Score: 213.60845000000003
- Max Citation Score: 217.73346
- Similarity Product: 159.80225855287313

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test