PATENT CLAIM ANALYSIS

Application Number: 16048975
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "006120"]

Abstract:
A system and method for capturing and analyzing a set of cells, comprising: an array including a set of parallel pores, each pore including a chamber including a chamber inlet and a chamber outlet, and configured to hold a single cell, and a pore channel fluidly connected to the chamber outlet; an inlet channel fluidly connected to each chamber inlet of the set of parallel pores; an outlet channel fluidly connected to each pore channel of the set of parallel pores; a set of electrophoresis channels fluidly coupled to the outlet channel, configured to receive a sieving matrix for electrophoretic separation; and a set of electrodes including a first electrode and a second electrode, wherein the set of electrodes is configured to provide an electric field that facilitates electrophoretic analysis of the set of cells.

Claim (Index 1):
A method for capturing and analyzing a population of target cells in single-cell format, comprising:\n dispensing a biological sample containing the population of target cells into an inlet channel directly fluidly coupled to a set of chambers defined within a broad surface of a substrate; receiving, into at least a portion of chambers of the set of chambers, exactly one of a target cell of the population of target cells from a direction substantially perpendicular to the broad surface of the substrate; at a fluid delivery module fluidly connected to an inlet channel, flowing a reagent fluid into the inlet channel, wherein the reagent fluid flows along the inlet channel in a direction substantially parallel to the broad surface of the substrate and accesses the set of chambers without egressing the population of target cells from the set of chambers; and performing a biochemical process within the set of chambers, wherein the reagent fluid interacts with the population of target cells retained within the set of chambers, thereby enabling analysis of the population of target cells in single-cell format.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 2.67273
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14163185', '14163153', '16048073', '15442222', '16048104']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6353022125314675
- 35 USC 102 Novelty (BERT): 0.4940518039158744
- Combined Prediction Score: 0.6211771716699082
- Mean Citation Score: 227.351272
- Max Citation Score: 241.7627
- Similarity Product: 179.85218665494918

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test