PATENT CLAIM ANALYSIS

Application Number: 16060836
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["549", "286000"]

Abstract:
Disclosed is a configurational stereoisomer, referred to as enantiomer E 4 , of bromadiolone, having, as determined by the chromatographic analysis carried out under conditions described hereinafter, a retention time t 4  with a value such that t 1 <t 2 <t 3 <t 4 ; t 1 , t 2  and t 3  representing the retention times of each configurational stereoisomer of bromadiolone different from the enantiomer E 4 , the analysis being carried out at a temperature of 27.3° C.

Claim (Index 22):
Chromatographic process for obtaining said enantiomer E 4  according to  claim 12 , in which:\n a high-pressure liquid chromatography column of dimensions 150\u00d72 mm, and containing a chiral stationary phase constituted of particles of cellulose tris(3,5-dimethylphenyl carbamate), is chosen, said particles having a mean size of 3 \u03bcm and having a mean pore size of 1000 \u212b; a mixture formed from acetonitrile (A) and water comprising 0.1% by volume of formic acid (B), with an A/B volume ratio of 80/20, is chosen as liquid mobile phase; the separation is performed at room temperature; a liquid composition containing said enantiomer E 4  dissolved in acetonitrile is introduced into the top of the chromatography column; and then the liquid mobile phase is passed at a flow rate of 0.25 mL/min through the chromatography column after the liquid composition, and a fraction of the mobile phase comprising said enantiomer E 4  is collected at the column outlet, separately from the configurational stereoisomers of bromadiolone different from said enantiomer E 4 , and with a retention time t 4  having a value such that t 1 <t 2 <t 3 <t 4 ; t 1 , t 2  and t 3  being the retention times of each of the configurational stereoisomers of bromadiolone different from said enantiomer E 4 ; and\n the liquid mobile phase of said fraction is removed so as to obtain said enantiomer E 4 .

Metadata:
- Claim Count in Document: 38.0
- Percentile: 94.0
- Lexical Diversity: 1.8
- Patent Class: 549.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16061115', '16061084', '15735677', '15318123', '15318195']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7663831654524822
- 35 USC 102 Novelty (BERT): 0.5729406078175432
- Combined Prediction Score: 0.7470389096889883
- Mean Citation Score: 391.37094400000007
- Max Citation Score: 514.50323
- Similarity Product: 369.308896047728

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test