PATENT CLAIM ANALYSIS

Application Number: 16043833
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["514", "299000"]

Abstract:
The present invention provides compositions containing clopidogrel, present as a free base or a pharmaceutically acceptable salt thereof, and sulfoalkyl ether cyclodextrin (SAE-CD). The compositions can be liquid, suspension or solid compositions. They can be adapted for oral, peroral or parenteral administration. The SAE-CD serves to aid in dissolution and stabilization of the clopidogrel in aqueous media. The stability of clopidogrel against hydrolytic degradation, thermal degradation, and photolytic degradation are improved. SAE-CD provides improved results over other cyclodextrin derivatives. The SAE-CD-containing composition of clopidogrel can be provided in liquid form, solid form or as a reconstitutable powder. Both ready-to-use and concentrated liquid compositions can be prepared. The liquid composition is optionally available as a clear solution. The compositions herein can be administered perorally or parenterally and provide substantial pharmacokinetic, pharmacodynamic and/or therapeutic advantages over a tablet composition administered perorally and excluding SAE-CD.

Claim (Index 9):
The kit of  claim 5 , wherein the solid pharmaceutical composition comprises an admixture of SAE-CD and clopidogrel.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 95.0
- Lexical Diversity: 1.86207
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15454967', '14846049', '12597908', '14507693', '13689898']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8498045829572373
- 35 USC 102 Novelty (BERT): 0.6087587980409691
- Combined Prediction Score: 0.8257000044656104
- Mean Citation Score: 583.916228
- Max Citation Score: 629.8613
- Similarity Product: 446.0911853434087

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test