PATENT CLAIM ANALYSIS

Application Number: 15891978
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "004000"]

Abstract:
A method is provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The method includes the steps of capturing the fraction-bound solid phase substrate and bringing an isolation buffer and the fraction-bound solid phase substrate into contact to purify the captured fraction-bound solid phase substrate.

Claim (Index 1):
A method for facilitating extraction of a fraction from a biological sample, the biological sample including non-desired material and a fraction-bound solid phase substrate, the method comprising the steps of:\n positioning at least a portion of a plunger within a passageway extending along axis through a barrel of a syringe, the plunger being slidable along the axis and including:\n an elongated stem having a first end received in the barrel; and \n a resilient plunger head extending radially from first end of the stem and terminating at a radially outer edge, the radially outer edge of the plunger head forming an airtight seal with an inner surface of the barrel; \n sliding the plunger along the axis of the barrel in a first direction such that the plunger head is positioned adjacent an opening in a first end of the barrel; positioning the opening in the first end of the barrel in fluid communication with an isolation buffer; sliding the plunger along the axis of the barrel in a second direction, opposite to the first direction, for a first user-selected distance so as to draw the isolation buffer into the passageway in the barrel through the opening; positioning the opening in the first end of the barrel in fluid communication with the biological sample; sliding the plunger along the axis of the barrel in a second direction for a second user-selected distance so as to draw the biological sample into the passageway in the barrel through the opening; positioning a magnet adjacent to an outer surface of the barrel in proximity to the first end of the barrel such that a magnetic field generated by the magnet captures the fraction-bound solid phase substrate at a fixed location within the passageway through the barrel of the syringe; sliding the plunger along the axis of the barrel in the first direction so as to urge the biological sample from the passageway in the barrel through the opening while maintaining the captured fraction-bound solid phase substrate at the fixed location; sliding the plunger along the axis of the barrel in the first direction such that at least a portion of the isolation buffer contacts the captured fraction-bound solid phase substrate at the fixed location and flows out of the passageway in the barrel through the opening; removing the magnet from adjacent to an outer surface of the barrel such that the fraction-bound solid phase substrate is no longer captured at the fixed location within the passageway through the barrel of the syringe; and sliding the plunger along the axis of the barrel in the first direction such that the fraction-bound solid phase substrate is urged from the passageway in the barrel through the opening; wherein the isolation buffer and the biological sample are immiscible.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.77143
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13033351', '12713950', '14243086', '13604192', '13832860']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6099982423835189
- 35 USC 102 Novelty (BERT): 0.5041334365437901
- Combined Prediction Score: 0.599411761799546
- Mean Citation Score: 252.378954
- Max Citation Score: 281.75055
- Similarity Product: 207.15880376413463

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test