PATENT CLAIM ANALYSIS

Application Number: 16041239
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-04
Patent Classification: ["514", "007400"]

Abstract:
A method for purifying Apo A-I is provided including the steps of providing a solution comprising Apo A-I and guanidine hydrochloride and filtering the solution through a filter having a pore size in a range from 15 nm to 35 nm to thereby reduce viral contamination of the Apo A-I. An Apo A-I preparation is provided having at least a 12 log LRV (log reduction value) for a parvovirus; and/or at least 9 log LRV for a non-enveloped virus; and/or at least 8.5 log LRV for a lipid enveloped virus. Also provided are pharmaceutical compositions and reconstituted high density lipoprotein formulation comprising Apo A-I and methods of treating diseases disorders or conditions.

Claim (Index 56):
A method of administering rHDL to a mammalian subject in need thereof, comprising administering the rHDL formulation of  claim 39  to the subject.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 1.65278
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14910424', '15870203', '14893178', '13805488', '14633880']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7200329034513497
- 35 USC 102 Novelty (BERT): 0.547379674180388
- Combined Prediction Score: 0.7027675805242536
- Mean Citation Score: 264.35413600000004
- Max Citation Score: 417.9897
- Similarity Product: 207.41677670149508

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test