PATENT CLAIM ANALYSIS

Application Number: 16382727
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-10
Patent Classification: ["544", "280000"]

Abstract:
This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.

Claim (Index 1):
A compound of formula (I) and their pharmaceutically acceptable salt, solvate or polymorph thereof wherein R 1  is H, fluorine or methyl; R 2  is H, halogen or C 1-3  alkyl; R 3  is C 1-6  alkyl optionally substituted by aryl optionally further substituted by one or more substituents independently selected from aryloxy, halogen, aryl, alkylamino, dialkylamino, C 1-6  alkyl, carboxylic acid, carboxylic ester, carboxylic amide, nitrile, or C 1-6  alkoxy; or R 3  is C 1-6  alkyl optionally substituted by C 1-6  alkene, C 3-7  cycloalkyl or C 3-7  heterocycloalkyl; or R 3  is C 1-6  alkyl optionally substituted by C 1-6  alkoxy optionally further substituted by aryl; R 4  is C 1-8  alkyl optionally substituted by one or more substituents independently selected from hydroxyl, C 1-6  alkoxy, C 1-6  alkyl, C 3-7  cycloalkyl, C 2-6  alkenyl, aryl, heteroaryl optionally further substituted by C 1-6  alkyl, and C 3-7  cycloalkyl optionally further substituted by C 1-6  alkyl; with the proviso that 2-amino, 4-(N-butylamino)-5-(alphamethylbenzyl)pyrrolo[3,2-d] pyrimidine is excluded.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 100.0
- Lexical Diversity: 1.12
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15333947', '14434021', '14392214', '14110054', '15209637']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7725745893385999
- 35 USC 102 Novelty (BERT): 0.531352528166872
- Combined Prediction Score: 0.7484523832214272
- Mean Citation Score: 327.854744
- Max Citation Score: 355.24475
- Similarity Product: 332.53205632062264

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test