PATENT CLAIM ANALYSIS

Application Number: 15953083
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "178000"]

Abstract:
The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system (CNS), or the brain, caused or mediated by NFkB, IL-6, IL-6-R, NADPH oxidase (Nox), and/or superoxide and/or hydrogen peroxide production by a NADPH oxidase, including for example ameliorating, treating, reversing or preventing schizophrenia, psychosis, delirium, e.g., post-operative delirium, drug-induced psychosis, psychotic features associated with frailty syndrome (FS), aging, depression, dementias; traumatic war neurosis, post traumatic stress disorder (PTSD) or post-traumatic stress syndrome (PTSS), Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's Disease), and/or Multiple Sclerosis (MS). The invention also provides methods for purifying a C60 fullerene, C 3  (tris malonic acid C60) or malonic acid derivatives.

Claim (Index 14):
The method of  claim 12 , wherein administering the C60 malonic acid derivative in vivo to an individual in need thereof: treats, ameliorates, slows the progress of, abates, prevents or reverses: neuron damage, CNS damage or brain damage in an individual having frailty syndrome (FS), aging, an injury, a pathology, a disease, an infection, a condition causing and/or associated with an increased amount of CNS inflammation and/or CNS oxidative stress; or accelerating the recovery of CNS neuron or brain damage in individuals having an injury, a pathology, an Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's Disease), Multiple Sclerosis (MS)), and/or cognitive, learning or memory impairments resulting therefrom, a disease, an infection and/or a condition causing and/or associated with an increased amount of CNS inflammation and/or CNS oxidative stress, and/or cognitive, learning or memory impairments resulting therefrom.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 1.81818
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15136787', '12681743', '14358571', '13970639', '14888390']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7667033577358231
- 35 USC 102 Novelty (BERT): 0.6548088775255488
- Combined Prediction Score: 0.7555139097147957
- Mean Citation Score: 411.3179859999999
- Max Citation Score: 801.0581
- Similarity Product: 561.2372747457741

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test