PATENT CLAIM ANALYSIS

Application Number: 15745461
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["548", "255000"]

Abstract:
The disclosure provides process developments and novel routes for the preparation of the NK-1 receptor antagonist, Compound (I) and intermediates in those routes.

Claim (Index 1):
A method of preparing Compound (I): comprising:\n contacting Compound (XII) \n with Compound (III) in the presence of a palladium, nickel, cobalt, iron or copper catalyst in an aprotic and substantially anhydrous solvent, optionally in the presence of a phosphine, optionally in the presence of ZnCl 2 , optionally in the presence of lithium chloride, wherein L1 is selected from the group consisting of I, Br, Cl, C 1 -C 2  alkanesulfonate, C 1 -C 2  perfluoromethanesulfonate, FSO 3 , and and\n L2 is selected from the group consisting of I, Br, Cl, C 1 -C 2  alkanesulfonate, C 1 -C 2  perfluoromethanesulfonate, and acetate.

Metadata:
- Claim Count in Document: 108.0
- Percentile: 86.0
- Lexical Diversity: 1.125
- Patent Class: 548.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14853883', '14946137', '15355630', '15841828', '13889980']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6738505092658369
- 35 USC 102 Novelty (BERT): 0.4885572689071952
- Combined Prediction Score: 0.6553211852299727
- Mean Citation Score: 216.948504
- Max Citation Score: 220.2003
- Similarity Product: 173.81787027071715

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test