PATENT CLAIM ANALYSIS

Application Number: 16107689
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "158000"]

Abstract:
Provided herein (among other things) are protease inhibitor compounds having enhanced features, along with methods for administering such compounds. For example, the subject compounds can be administered without concomitant administration of a CYP3A4 inhibitor, have increased therapeutic index and/or increased potency, and are low-resistance inducing in nature.

Claim (Index 19):
Use of an HIV protease inhibitor conjugate as a protease inhibitor monotherapy in a biological system infected with HIV, in a method which comprises administering the HIV protease inhibitor conjugate, wherein: (i) in a biological model in which the HIV protease inhibitor conjugate is periodically added in a given molar amount over time, and in the same biological model in which the same HIV protease inhibitor in unconjugated form is periodically added over time in the same given molar amount, the biological model in which the corresponding HIV protease inhibitor in unconjugated form is added is more likely to exhibit HIV protease resistance, and (ii) the HIV protease inhibitor conjugate retains at least substantially the same HIV protease inhibitor activity on a molar basis in a suitable model or patient.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 96.0
- Lexical Diversity: 1.19565
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15228793', '12530363', '14055581', '13933319', '13411089']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7563282317300396
- 35 USC 102 Novelty (BERT): 0.6594310623740703
- Combined Prediction Score: 0.7466385147944428
- Mean Citation Score: 321.917588
- Max Citation Score: 658.2316
- Similarity Product: 608.9617334935665

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test