PATENT CLAIM ANALYSIS

Application Number: 15780289
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "210180"]

Abstract:
In its many embodiments, the present invention provides certain substituted bispiperidinyl compounds of the Formula (I): and pharmaceutically acceptable salts thereof, wherein ring A, ring B, R 1 , R 2 , R 3 , L, R 4 , X, Z, Li, Q and R5 are as defined herein. The novel compounds of the invention, and pharmaceutically acceptable compositions comprising a compound thereof, are useful as Liver X-β receptor (LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory diseases and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.

Claim (Index 5):
The compound according to,  claim 1 , or a pharmaceutically acceptable salt thereof, wherein:\n L is \u2014C(O)\u2014; and R 3  is \u2014N(R N1 )(R N2 ), wherein: R N1  is selected from the group consisting of H and \u2014(C 1 -C 6 )alkyl; and R N2  is selected from the group consisting of: H, \u2014(C 1 -C 6 )alkyl, \u2014O\u2014(C 1 -C 6 )alkyl, \u2014OH, halogen, \u2014CN, and \u2014(C 1 -C 6 )alkyl which is substituted with 1 or 2 groups independently selected from the group consisting of:\n OH, halogen, \u2014CN, \n \u2014NH 2 , \u2014NH(C 1 -C 6 )alkyl, \u2014N((C 1 -C 6 )alkyl) 2 , \n optionally substituted phenyl, (wherein said optional substitutents on said phenyl are 1 to 3 groups independently selected from OH, CN, \u2014(C 1 -C 4 )alkyl, \u2014(C 1 -C 4 )alkoxyl), \n optionally substituted heteroaryl, (wherein said optional substituents on said heteroaryl are 1 to 3 groups independently selected from \u2014(C 1 -C 6 )alkyl, \u2014(C 1 -C 4 )alkoxyl, and cyclopropyl), \n optionally substituted cyclopropyl (wherein said optional substituents on said cyclopropyl are 1 to 3 groups independently selected from \u2014(C 1 -C 6 )alkyl), and \n optionally substituted heterocycloalkyl (wherein said optional substitutents on said heterocycloalkyl are 1 to 3 groups independently selected from halogen, \u2014OH, oxo, CN, and \u2014(C 1 -C 6 )alkyl.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.53571
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15774157', '14721262', '15204422', '14657179', '15182749']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7989088025336795
- 35 USC 102 Novelty (BERT): 0.5743027573598375
- Combined Prediction Score: 0.7764481980162954
- Mean Citation Score: 351.86578
- Max Citation Score: 468.0021
- Similarity Product: 381.79380310875183

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test