PATENT CLAIM ANALYSIS

Application Number: 15775319
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-03
Patent Classification: ["544", "349000"]

Abstract:
There is described herein use of a compound of formula (I) below to make cyclic peptides.

Claim (Index 1):
A compound of formula (I): wherein\n R 1 , R 2 , R 3 , R 4 , R 5  and R 6  are each independently selected from the group consisting of a protecting group; H; lower alkyl; aryl; heteroaryl; alkenyl; heterocycle; acids of the formula \u2014C(O)OH; esters of the formula \u2014C(O)OR* wherein R* is selected from alkyl and aryl; amides of the formula \u2014C(O)NR**R***, wherein R** and R*** are independently selected from H, alkyl and aryl; \u2014CH2C(O)R, wherein R is selected from \u2014OH, lower alkyl, aryl, -loweralkyl-aryl, or \u2014NRaRb, where Ra and Rb are independently selected from H, lower alkyl, aryl or -loweralkyl-aryl; \u2014C(O)Rc, wherein Rc is selected from lower alkyl, aryl or -lower alkyl-aryl; or -lower alkyl-ORd, wherein Rd is a suitable protecting group or OH group; all of which are optionally substituted at one or more substitutable positions with one or more suitable substituents;\n provided that R 3  or R 4  can be covalently linked to R 1  or R 2  to form a cyclic secondary amine, and/or to R 5  or R 6  to form a ring; R 3  and R 4  may be covalently linked to each other to form a ring; and R 5  and R 6  may be covalently bound to each other to form a ring; \n \n R 7  is H, a protecting group, lower alkyl, benzyl, alkenyl, lower alkyloxy; aryl; heteroaryl; heterocycle; \u2014C(O)R****, wherein R**** is independently selected from alkyl, aryl, heteroaryl, amino, aminoalkyl, aminoaryl, aminoheteroaryl, alkoxy, aryloxy, heteroaryloxy; \u2014CH 2 C(O)R; \u2014C(O)Rc; all of which are optionally substituted at one or more substitutable positions with one or more suitable substituents,\n or along with R 8  or R 9 , a cyclic side chain of a proteinogenic or a non-proteinogenic amino acid having, the N-terminus thereof being the N\u2014R 7 , wherein the proteinogenic or a non-proteinogenic amino acid can be substituted with a suitable substituent; \n \n R 8  and R 9  are independently selected from the amino acid side chains of a proteinogenic or a non-proteinogenic amino acid having, the N-terminus thereof being the N\u2014R 7 , or may form a cyclic side chain with R 7 ; and \n R 10  is H, a protecting group, a resin, lower alkyl, allyl, tert-butyl, or benzyl; \n stereocentres 1*, 2* and 3* are each independently selected from R and S; and \n n is 1, 2, 3, or 4 and where n is 2-4, each R 8  and each R 9  are independent of each other.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 1.05556
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12446343', '13257159', '14962952', '11426287', '12136874']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7921047573339092
- 35 USC 102 Novelty (BERT): 0.5281139984772508
- Combined Prediction Score: 0.7657056814482434
- Mean Citation Score: 315.69614199999995
- Max Citation Score: 351.15
- Similarity Product: 302.49392446875567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test