PATENT CLAIM ANALYSIS

Application Number: 15939952
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "233200"]

Abstract:
Compounds discovered through a high-throughput screen, along with methods of use of the compounds, are provided. The compounds can be used to strongly inhibit key drug targets found in protozoan parasites, e.g., the target  Trypanosoma cruzi  glucokinase. Compounds include derivatives of N-phenylbenzenesulfonamide, barbituric acid, (R)-3-(piperidin-2-yl)pyridine, 3-nitro-2-phenyl-2H-chromene, 6-amino-3-methyl-4-phenyl-1,4-dihydropryranole[2,3-c]pyrazole-5-carbonitrile, and gossypol (2,2′-Bis(formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene).

Claim (Index 3):
The pharmaceutical composition of  claim 2 , in which:\n R 1 , R 2 , R 8  are independently selected from hydrogen or halogen; R 3 , R 4 , R 5 , R 6 , R 10  are independently selected from hydrogen, halogen, methyl, methoxy, or ethoxy; and R 7 , R 9  are independently selected from hydrogen, halogen, hydroxyl, methoxy, methyl sulfide, or are components of a conjugated ring fused to the aryl group.

Metadata:
- Claim Count in Document: 46.0
- Percentile: 90.0
- Lexical Diversity: 1.35088
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14405159', '11818224', '12356745', '14927390', '12412658']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7476341092531865
- 35 USC 102 Novelty (BERT): 0.4800224420356442
- Combined Prediction Score: 0.7208729425314323
- Mean Citation Score: 184.092424
- Max Citation Score: 185.51794
- Similarity Product: 140.0024950358236

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test