PATENT CLAIM ANALYSIS

Application Number: 15956133
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-04
Patent Classification: ["514", "017700"]

Abstract:
Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example, glaucoma and optic nerve injury. The viability of the retinal ganglion cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells and/or promote axon regeneration, thereby minimizing the loss of vision or visual function associated with the ocular disorder.

Claim (Index 48):
The method of  claim 1 , wherein the necrosis inhibitor is a compound selected from the group consisting of a compound of Formula I-B: or a pharmaceutically acceptable salt, an ester, or a prodrug thereof; a compound of Formula I-C: or a pharmaceutically acceptable salt, an ester, or a prodrug thereof; and a compound of Formula I-D: or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 73.0
- Percentile: 91.0
- Lexical Diversity: 1.66102
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15093480', '15288214', '14934810', '12086792', '15100967']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8169645921165458
- 35 USC 102 Novelty (BERT): 0.6879601724744651
- Combined Prediction Score: 0.8040641501523378
- Mean Citation Score: 535.4984059999998
- Max Citation Score: 823.15753
- Similarity Product: 662.4012566860127

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test