PATENT CLAIM ANALYSIS

Application Number: 15966613
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "254070"]

Abstract:
The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.

Claim (Index 16):
The method of  claim 1 , further comprising monitoring the proliferation disorder in the subject, wherein a lack of clinical response in the proliferation disorder to the treatment is indicative that the plasma trough level of the HhP inhibitor should be increased further above about 1000 ng/mL, and wherein the occurrence of a clinical response and a plasma trough level of the HhP inhibitor substantially higher than about 1000 ng/mL indicates that one or more subsequent doses of the HhP inhibitor can be reduced.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 91.0
- Lexical Diversity: 1.27273
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15420283', '15966844', '15420247', '14173588', '11990729']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7946742053728082
- 35 USC 102 Novelty (BERT): 0.6678684921391101
- Combined Prediction Score: 0.7819936340494383
- Mean Citation Score: 570.6201560000002
- Max Citation Score: 657.5403
- Similarity Product: 654.6154845855652

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test