PATENT CLAIM ANALYSIS

Application Number: 15542380
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "049000"]

Abstract:
The present invention provides methods and compositions for treatment of acute inflammatory diseases or disorders and/or for treatment of lung injury. Certain exemplary methods involve administering an IL-4 polypeptide or fragment thereof possessing cytokine activity or an IL-4 agonist systemically to a subject having an inflammatory disease or disorder and/or a lung injury. Other exemplary methods involve administering an inhibitor of DNA methylation systemically to a subject and/or administering an inhibitor of DNA methylation to a cell population comprising T cells (e.g., Treg cells) for introduction/re-introduction to a subject having an inflammatory disease or disorder and/or a lung injury. Compositions and cells for use in such methods are also provided.

Claim (Index 33):
A method for treating an acute inflammatory disease or disorder in a subject, the method comprising:\n identifying a subject having an acute inflammatory disease or disorder, and administering an IL-4 polypeptide or fragment thereof possessing cytokine activity, or an IL-4 agonist to the subject, thereby treating the acute inflammatory disease or disorder in the subject, or A method for treating a lung injury in a subject, the method comprising: identifying a subject having a lung injury, and administering an IL-4 polypeptide or fragment thereof possessing cytokine activity, or an IL-4 agonist to the subject, thereby treating the lung injury in the subject, or A method for treating influenza in a subject, the method comprising: identifying a subject having influenza, and administering an IL-4 polypeptide or fragment thereof possessing cytokine activity, or an IL-4 agonist to the subject, thereby treating influenza in the subject, or A method for treating a live bacterial infection in a subject, the method comprising: identifying a subject having a live bacterial infection, and administering an IL-4 polypeptide or fragment thereof possessing cytokine activity, or an IL-4 agonist to the subject, thereby treating the live bacterial infection in the subject.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 86.0
- Lexical Diversity: 1.91803
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14764325', '15138120', '10682130', '13237831', '14359850']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6965228157016579
- 35 USC 102 Novelty (BERT): 0.5248706168650217
- Combined Prediction Score: 0.6793575958179943
- Mean Citation Score: 302.65005
- Max Citation Score: 305.9192
- Similarity Product: 209.1357583322525

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test