PATENT CLAIM ANALYSIS

Application Number: 15763566
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["424", "130100"]

Abstract:
The present invention relates to biofunctionalized nanoparticles and uses thereof in adoptive cell therapy. In particular, the present invention relates to a nanoparticle comprising an amount of at least one antigen and an amount of at least one antibody having specificity for a B cell receptor wherein the antigen and antibody are attached to the surface of the nanoparticle.

Claim (Index 14):
A method of treating a cancer, an infectious disease, an autoimmune disease, an allergy, an immune reaction against a molecule that is exogenously administered for a therapeutic purpose or an immune reaction against a grafted tissue or grafted hematopoietic cells or grafted blood cells in a subject in need thereof comprising administering to the subject a therapeutically effective amount of\n the nanoparticles according to  claim 1 , a population of antigen-presenting B cells prepared by incubating B cells with a amount of the nanoparticles for a time sufficient to allow internalization of the nanoparticles into the B cells and isolating B cells that present the at least one antigen at their surface, or a population of antigen-specific T cells prepared by T cells in the presence of the antigen presenting B cells.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 1.58974
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11517814', '11632442', '10561517', '15106400', '12669940']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7326472413585832
- 35 USC 102 Novelty (BERT): 0.5126548886308876
- Combined Prediction Score: 0.7106480060858137
- Mean Citation Score: 268.947066
- Max Citation Score: 279.64188
- Similarity Product: 180.21041167517424

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test