PATENT CLAIM ANALYSIS

Application Number: 15987993
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["435", "320100"]

Abstract:
Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations containing them. Also provided are methods of preparing and using the disclosed capsid-protein-mutated rAAV constructs in a variety of diagnostic and therapeutic modalities, including, inter alia, as mammalian cell-targeting delivery agents, and as human gene therapy vectors. Also disclosed are large-scale production methods for capsid-modified rAAV expression vectors, viral particles, and infectious virions having improved transduction efficiencies over those of the corresponding, un-modified, rAAV vectors, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications.

Claim (Index 38):
The rAAV vector of  claim 37 , wherein the modified AAV capsid protein is of a serotype selected from the group consisting of AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, and AAV10, as set forth in SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO: 6, SEQ ID NO:7, SEQ ID NO: 8, SEQ ID NO:9, and SEQ ID NO:10, respectively.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 93.0
- Lexical Diversity: 1.84375
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14214011', '15444235', '14401442', '13840224', '13854011']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7927193800301177
- 35 USC 102 Novelty (BERT): 0.6580470886329797
- Combined Prediction Score: 0.7792521508904038
- Mean Citation Score: 662.089968
- Max Citation Score: 792.17664
- Similarity Product: 614.041038713379

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test