PATENT CLAIM ANALYSIS

Application Number: 15982038
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "249000"]

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Claim (Index 2):
The compound of  claim 1  having Formula (II): or a stereoisomer, tautomer, pharmaceutically acceptable salt thereof, wherein:\n X, Y, and Z are independently selected from the group consisting of: N and CR 5 ; provided one of X, Y, and Z is N; \n R 1 , at each occurrence, is selected from the group consisting of: H, halo, C 1-2  alkyl, \u2014O(C 1-4  alkyl), and \u2014C(\u2550NH)NH 2 ; \n R 4a , R 4b , R 4c , and R 4d  are independently selected from the group consisting of: H, F, and C 1-4  alkyl; \n R 5  is selected from the group consisting of: H, halo, NO 2 , \u2014NH 2 , \u2014NR 9 COC 1-4  alkyl, \u2014NR 9 CO 2 C 1-4  alkyl, \u2014NR 9 CONH(C 1-4  alkyl), \u2014NR 9 \u2014C 1-4  alkylene-N(C 1-4  alkyl) 2 , R 8 , \u2014NR 9 COR 8 , \u2014NR 9 CO 2 R 8 , and \u2014NR 9 CONR 9 R 8 ; \n R 8  is, independently at each occurrence, selected from the group consisting of: \u2014(CH 2 ) n \u2014C 3-6  cycloalkyl, \u2014(CH 2 ) n -phenyl and \u2014(CH 2 ) n -5- to 10-membered heterocycle containing carbon atoms and 1-4 heteroatoms selected from the group consisting of N, NH, N(C 1-4  alkyl), O, and S; wherein said cycloalkyl, phenyl, or heterocycle is substituted with 0-3 R b ; \n R b  is selected from the group consisting of: \u2550O, halo, C 1-4  alkoxy, and CONH 2 ; and \n n, at each occurrence, is selected from 0, 1, 2, and 3.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.17949
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15643891', '15183051', '14799681', '14350411', '14350417']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8312636350788175
- 35 USC 102 Novelty (BERT): 0.511859292965206
- Combined Prediction Score: 0.7993232008674565
- Mean Citation Score: 315.033496
- Max Citation Score: 316.3271200000001
- Similarity Product: 276.6596781555558

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test