PATENT CLAIM ANALYSIS

Application Number: 16441103
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-09
Patent Classification: ["424", "499000"]

Abstract:
The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.

Claim (Index 1):
A stable aqueous pharmaceutical composition comprising\n (a) about 25 to about 75 mg/mL etanercept, (b) about 1 to about 10 wt. % sucrose, (c) up to about 10 wt. % polyol or an amino acid, wherein the sucrose has a ratio of between 5:1 to 1:5 to the polyol or the amino acid, and (d) an aqueous carrier, wherein said composition (i) is free of arginine, (ii) has a pH of about 6.0 to about 6.6, and (iii) has at M 3  or T 2  or T 4  no more than, on average, about 10,000 subvisible particles per mL having a size greater than 5 \u03bcm, and wherein said amino acid is not cysteine and is not arginine, and the combination of said sucrose and said polyol or amino acid stabilizes said etanercept in said stable aqueous pharmaceutical composition.

Metadata:
- Claim Count in Document: 62.0
- Percentile: 100.0
- Lexical Diversity: 1.34783
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15917333', '15078755', '13654950', '13654770', '13654735']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7742058000999607
- 35 USC 102 Novelty (BERT): 0.5634141527989854
- Combined Prediction Score: 0.7531266353698631
- Mean Citation Score: 420.363612
- Max Citation Score: 445.05426
- Similarity Product: 380.4157160212612

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test