PATENT CLAIM ANALYSIS

Application Number: 15977238
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "256000"]

Abstract:
Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.

Claim (Index 1):
A method for the reduction of at least one point in severity of nonalcoholic fatty liver disease or nonalcoholic steatohepatitis grading scoring systems, reduction of the level of serum markers of nonalcoholic steatohepatitis activity, reduction of nonalcoholic steatohepatitis disease activity or reduction in the medical consequences of nonalcoholic steatohepatitis in humans comprising the step of administering to a human in need of such reduction an effective amount of a compound according to Formula (I) or a pharmaceutically acceptable salt of said compound to a patient in need thereof;\n wherein the compound of Formula (I) is: wherein\n D 1  and D 2  are each independently N or CH; \n R 1  is H, or (C 1 -C 2 )alkyl optionally substituted with one or two substituents each independently selected from fluoro and (C 3 -C 6 )cycloalkyl; \n R 2  is H or fluoro; \n R 3  is, \n R 4  is H, cyano, or (C 1 -C 4 )alkyl optionally substituted with one or two substituents each independently selected from \u2014OH and \u2014S(O) 2 R 6 ; R 5  is H or \u2014OH; and R 6  is (C 1 -C 4 )alkyl.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.18519
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15674914', '14643210', '15193440', '15693785', '14384508']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7259685577216995
- 35 USC 102 Novelty (BERT): 0.5463840734526675
- Combined Prediction Score: 0.7080101092947964
- Mean Citation Score: 279.31827200000004
- Max Citation Score: 385.5273
- Similarity Product: 303.7882232082904

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test