PATENT CLAIM ANALYSIS

Application Number: 15891585
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "248000"]

Abstract:
This invention is directed to compounds of formula (I): where r, q, R, R 2 , R 3 , R 4 , R 5a , R 5b , R 5c , R 6a , R 6b , R 6c , R 7 , R 8 , and R 9  are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A 4  hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

Claim (Index 18):
The method according to  claim 16  wherein:\n r is 0; \n R 2  and R 7 , together with the nitrogens to which they are attached, form hexahydro-1H-diazepinyl (optionally substituted with oxo); \n R 3  is a direct bond, \u2014O\u2014, \u2014R 12 \u2014O\u2014, \u2014O\u2014R 12 \u2014, \u2014O\u2014R 12 \u2014O\u2014, or an optionally substituted straight or branched methylene or ethylene chain; \n R 4  is a direct bond, \u2014O\u2014R 12a \u2014, or an optionally substituted straight or branched methylene, ethylene or propylene chain; \n each R 5a , R 5b , R 5c , R 6a , R 6b  and R 6c  are each independently selected from hydrogen, alkyl, haloalkyl or hydroxyalkyl; \n each R 12  is a methylene, ethylene or propylene chain (each optionally substituted with one or more substituents selected from the group consisting of \u2014OR 10 ); and \n R 12a  is a methylene, ethylene or propylene chain (each optionally substituted with one or more substituents selected from the group consisting of \u2014OR 10 ).

Metadata:
- Claim Count in Document: 76.0
- Percentile: 88.0
- Lexical Diversity: 1.75714
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14313672', '11644244', '14849810', '12771659', '15840097']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8002308491597852
- 35 USC 102 Novelty (BERT): 0.5911213529261706
- Combined Prediction Score: 0.7793198995364237
- Mean Citation Score: 393.50533800000005
- Max Citation Score: 528.1824
- Similarity Product: 413.29480961608886

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test