PATENT CLAIM ANALYSIS

Application Number: 16043504
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-03
Patent Classification: ["424", "135100"]

Abstract:
The disclosure is directed to novel predictive methods and personalized therapies for treating asthma. Specifically, this disclosure relates to methods of treating a patient having asthma by selectively administering an IL-13 antagonist, on the basis of that patient being genetically predisposed to have a favorable response to treatment with the IL-13 antagonist. Also disclosed herein are transmittable forms of information, diagnostic methods, and kits useful in predicting the likelihood that a patient having asthma will respond to treatment with an IL-13 antagonist.

Claim (Index 15):
The method according to  claim 1 , wherein the IL-13 antagonist is an antibody selected from the group consisting of:\n i. an antibody comprising one or more of the CDRs selected from the list consisting of: (a) the V H  CDR1s shown in SEQ ID NOs: 2 or 5 (b) the V H  CDR2s shown in SEQ ID NOs: 3 or 6, (c) the V H  CDR3s shown in SEQ ID NOs: 4 or 7 (d) the V L  CDR1s shown in SEQ ID NOs: 8 or 11, (e) the V L  CDR2s shown in SEQ ID NOs: 9 or 12, (f) the V L  CDR3s shown in SEQ ID NOs: 10 or 13; ii. an antibody comprising a heavy chain variable region CDR1 of SEQ ID NO: 2; a heavy chain variable region CDR2 of SEQ ID NO: 3; a heavy chain variable region CDR3 of SEQ ID NO: 4; a light chain variable region CDR1 of SEQ ID NO: 8; a light chain variable region CDR2 of SEQ ID NO: 9; and a light chain variable region CDR3 of SEQ ID NO: 10; iii. an antibody comprising a heavy chain variable region CDR1 of SEQ ID NO: 5; a heavy chain variable region CDR2 of SEQ ID NO: 6; a heavy chain variable region CDR3 of SEQ ID NO: 7; a light chain variable region CDR1 of SEQ ID NO: 11; a light chain variable region CDR2 of SEQ ID NO: 12; and a light chain variable region CDR3 of SEQ ID NO: 13, and iv. an antibody comprising a heavy chain variable region as recited in SEQ ID NO: 14 and a light chain variable region as recited in SEQ ID NO: 16.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 95.0
- Lexical Diversity: 1.58929
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15302348', '15969952', '14978183', '14457566', '15041514']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6576370650405803
- 35 USC 102 Novelty (BERT): 0.5732445885800129
- Combined Prediction Score: 0.6491978173945235
- Mean Citation Score: 300.79763
- Max Citation Score: 503.8454
- Similarity Product: 335.7119791746616

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test