PATENT CLAIM ANALYSIS

Application Number: 15575778
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2018-10
Patent Classification: ["544", "293000"]

Abstract:
The present invention relates to an improved process for the preparation of N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyl amino)-(2E)-2-butenamide (2Z)-2-butenedioate (1:2) represented by the following structural formula:

Claim (Index 25):
The process according to  claims 23  &  24 , wherein,\n In step-(a) the suitable solvent used is selected from hydrocarbon solvents, ether solvents, ester solvents, polar-aprotic solvents, chloro solvents, ketone solvents, nitrile solvents, alcohol solvents, polar solvents, formic acid, acetic acid, alkyl ethers of ethylene glycol and propylene glycol; \n In step-(b) removal of solvent can be carried by suitable techniques includes but not limited to evaporation, evaporation under reduced pressure, flash evaporation, vacuum drying, concentrating the reaction mixture, atmospheric distillation, vacuum distillation, distillation by using a rotational distillation device such as a Buchi Rotavapor, agitated thin film drying, melt extrusion, spray drying, freeze drying (lyophilization), spray-freeze drying, addition of suitable anti-solvent to the reaction mixture followed by filtration of the precipitated solid and cooling the clear solution to lower temperatures to precipitate the solid followed by filtration of the reaction.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 97.0
- Lexical Diversity: 1.46154
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15516382', '15565996', '15553843', '13138429', '11997719']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5552805759765798
- 35 USC 102 Novelty (BERT): 0.5306599533729757
- Combined Prediction Score: 0.5528185137162194
- Mean Citation Score: 289.474582
- Max Citation Score: 317.6971
- Similarity Product: 206.3292729002833

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test