PATENT CLAIM ANALYSIS

Application Number: 15743546
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["546", "153000"]

Abstract:
Compounds that inhibit Myeloid Cell Leukemia-1 (Mcl-1) oncoprotein, and methods of using the same, are provided for treating disease.

Claim (Index 7):
A compound comprising formula (IIIa) or formula (IIIb): wherein each R 31  can independently represent a substituent selected from the group consisting of H and an optionally substituted alkyl, aryl, sulfinyl, and sulfonyl; A 31  is a bond or a substituent selected from the group consisting of S(\u2550O), S(\u2550O) 2 , C(\u2550O), C(\u2550O)O, and CH 2 ; X 31  is a substituent selected from the group consisting of optionally substituted alkyl and aryl; Y 31  is a substituent selected from the group consisting of \u2014C(O)O\u2014, \u2014CONR 31 \u2014, \u2014CONR 31 \u2014SO 2 \u2014, \u2014CONR 31 O\u2014, Z 31 , Z 32 , Z 33 , and Z 34  each can independently represent a substituent selected from the group consisting of H, halo, cyano, hydroxy, nitro, and optionally substituted acylsulfonamide, alkyl, alkylaryl, alkylhetaryl, alkylheterocycloalkyl, alkenyl, alkynyl, alkenyl-cycloalkyl, alkynyl-cycloalkyl, carboxaldehyde, carbonyl, carboxyl, cycloalkyl, cycloalkyl-alkenyl, cycloalkyl-heterocycloalkyl, cycloalkyl-heteroaryl, alkoxy, alkoxycarbonyl, acyl, acyloxy, amino, amido, aryl, aralkyl, ester, fluoroalkyl, heteroalkyl, heteroalkenyl, heteroalkynyl, heteroalkylaryl, heteroalkylheteroaryl, heteroalkylheterocycloalkyl, heteroalkylcycloalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl, hydroxamate, sulfanyl, sulfinyl, sulfonyl, sulfonamidyl, sulfoxyl, and sulfonate; and pharmaceutically acceptable salts, solvates, hydrates, cocrystals, or prodrugs thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.04348
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12104294', '12096393', '14763468', '13823810', '13526337']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7398831545253481
- 35 USC 102 Novelty (BERT): 0.5171524212587245
- Combined Prediction Score: 0.7176100811986857
- Mean Citation Score: 268.77087199999994
- Max Citation Score: 276.15472
- Similarity Product: 174.11017364154816

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test