PATENT CLAIM ANALYSIS

Application Number: 16362579
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-09
Patent Classification: ["530", "332000"]

Abstract:
The present invention relates to γ-PNA monomers according to Formula I where substituent groups R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.

Claim (Index 1):
A peptide nucleic acid (PNA) monomer having the following formula: wherein B is adenine, guanine, cytosine, thymine, or uracil; P is selected from the group consisting of hydrogen (H), 9-fluorenylmethyloxycarbonyl (Fmoc),\n t-butyloxycarbonyl (Boc), benzyloxycarbonyl (Cbz), benzyl (Bn), tosylate (Tos), allyloxycarbonyl (alloc), benzhydryloxycarbonyl (Bhoc), trityl (Trt), monomethoxytrityl (MMT) and dimethoxytrityl (DMT); \n each of R 1  and R 2  is independently selected from the group consisting of hydrogen (H), linear or\n branched (C 1 -C 8 )alkyl, (C 2 -C 8 )alkenyl, (C 2 -C 8 )alkynyl, (C 1 -C 8 )hydroxylalkyl, (C 3 -C 8 )aryl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )aryl(C 1 -C 6 )alkylene, (C 3 -C 8 )cycloalkyl(C 1 -C 6 )alkylene, and \n provided that at least one of R 1  and R 2  is each of R 3  and R 4  is independently selected from the group consisting of hydrogen (H) and R 5  is selected from the group consisting of hydrogen (H), linear or branched (C 1 -C 8 )alkyl, (C 2 -C 8 )alkenyl, (C 2 -C 8 )alkynyl, (C 1 -C 8 )hydroxylalkyl, (C 3 -C 8 )aryl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )aryl(C 1 -C 6 ) alkylene and (C 3 -C 8 )cycloalkyl(C 1 -C 6 ) alkylene; R 6  is selected from the group consisting of hydrogen (H), linear or branched (C 1 -C 8 )alkyl, substituted or unsubstituted (C 3 -C 8 )aryl and (C 3 -C 8 )aryl(C 1 -C 6 )alkylene; P 1  is selected from the group consisting of hydrogen (H), linear or branched (C 1 -C 8 )alkyl, 9-fluorenylmethyloxycarbonyl (Fmoc), t-butyloxycarbonyl (Boc), benzyloxycarbonyl (Cbz), benzyl (Bn), tosylate (Tos), allyloxycarbonyl (alloc), trityl (Trt), monomethoxytrityl (MMT) and dimethoxytrityl (DMT); n is an integer from 0 to 10, inclusive; and q is an integer from 0 to 10, inclusive.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 99.0
- Lexical Diversity: 1.54348
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14110689', '16145075', '14921755', '15972494', '14782471']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7355055133032227
- 35 USC 102 Novelty (BERT): 0.6049735687570118
- Combined Prediction Score: 0.7224523188486016
- Mean Citation Score: 457.167388
- Max Citation Score: 532.6466
- Similarity Product: 486.28840145694016

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test