PATENT CLAIM ANALYSIS

Application Number: 15745829
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "04400A"]

Abstract:
Process for inducing resistance to diphtheria toxin in a human cell, wherein the process is carried out in vitro and/or in vivo in a rodent xenografted with a human cell, the process comprising: a) providing at least one expression vector containing at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript of the human cell; c) transducing the at least one vector into the human cell; d) allowing transcription in the human cell, from the at least one expression vector, of the at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript; e) obtaining silencing of the DPH2 gene in the human cell, whereby the human cell is resistant to diphtheria toxin.

Claim (Index 1):
Process for inducing resistance to diphtheria toxin in a human cell, wherein the process is carried out in vitro and/or in vivo in a rodent xenografted with a human cell, the process comprising:\n a) providing at least one expression vector containing at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript of the human cell; b) transducing the at least one vector into the human cell; c) allowing transcription in the human cell, from the at least one expression vector, of the at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript; d) obtaining silencing of the DPH2 gene in the human cell, whereby the human cell is resistant to diphtheria toxin.

Metadata:
- Claim Count in Document: 52.0
- Percentile: 86.0
- Lexical Diversity: 2.27586
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13942394', '13982530', '12305008', '11680414', '14164625']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.662115551066304
- 35 USC 102 Novelty (BERT): 0.5010152311821322
- Combined Prediction Score: 0.646005519077887
- Mean Citation Score: 238.54697
- Max Citation Score: 244.50845
- Similarity Product: 190.1131250403792

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test