PATENT CLAIM ANALYSIS

Application Number: 15741786
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "154000"]

Abstract:
The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.

Claim (Index 13):
An aminopyrazine for use according to  claim 12  wherein the antimalarial agent is selected from artemisinin or an artemisinin and its derivatives (such as artemether or dihydroartemisinin, chloroquine, quinine, mefloquine, amodiaquine, atovaquone/proguanil, doxycycline, lumefantrine, piperaquine, pyronaridine, halofantrine, pyrimethamine-sulfadoxine, primaquine, quinacrine, doxycycline, atovaquone, proguanil hydrochloride, piperaquine, ferroquine, tafenoquine, arterolane, Spiro[3H-indole-3,1\u2032-[1H]pyrido[3,4-b]indol]-2(1H)-one, 5,7\u2032-dichloro-6\u2032-fluoro-2\u2032,3\u2032,4\u2032,9\u2032-tetrahydro-3\u2032-methyl-,(1\u2032R,3\u2032S)-(CAS Registry Number: 1193314-23-6), Sulfur, [4-[[2-(1,1-difluoroethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino]phenyl] pentafluoro-] (CAS Registry Number: 1282041-94-4), Morpholine, 4-[2-(4-cis-dispiro [cyclohexane-1,3\u2032,-[1,2,4]trioxolane-5\u2032,2\u2033-tricyclo[3.3.1.1 3,7 ]decan]-4-ylphenoxy)ethyl]-(CAS Registry Number: 1029939-86-3), [3,3\u2032-Bipyridin]-2-amine, 5-[4-(methylsulfonyl)phenyl]-6\u2032-(trifluoromethyl)-(CAS Registry Number: 1314883-11-8), Ethanone, 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydroimidazo [1,2-a]pyrazin-7(8H)-yl]-(CAS Registry Number 1261109-90-3).

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.63333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14379332', '14905369', '12833909', '13912898', '14978059']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7408873416167701
- 35 USC 102 Novelty (BERT): 0.513667096569443
- Combined Prediction Score: 0.7181653171120375
- Mean Citation Score: 233.309988
- Max Citation Score: 302.61624
- Similarity Product: 280.41087556368825

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test