PATENT CLAIM ANALYSIS

Application Number: 15771487
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "217060"]

Abstract:
To provide a compound having an inhibitory activity for an androgen receptor. A fused pyrimidine compound represented by the following formula (I) or a pharmaceutically acceptable thereof (in the formula, X, Y, Z, R 1 , and R 2  are as defined in the specification).

Claim (Index 10):
The compound or pharmaceutically acceptable salt thereof according to  claim 9 , wherein\n X represents a cyano group or a nitro group; Y represents a chlorine atom, a bromine atom, a trifluoromethyl group, a methoxy group, an isopropoxy group, or a methyl group; Z represents a hydrogen atom or a fluorine atom; R 1  is a substituent selected from the group consisting of the followings: R 2  represents a hydrogen atom, a methyl group, or a cyano group; Ra represents a phenyl group, a hydroxy-ethyl group, a hydroxy-isopropyl group, a hydroxy-oxetanyl group, a methoxy group, a trifluoromethoxy group, a 2-oxa-6-azaspiro[3.3]heptyl group, \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NRdRe, or an n-propoxy group substituted with a piperazinyl group which may be substituted with acetyl, tert-butoxycarbonyl, mesyl, or methyl; Rb represents a hydrogen atom, a fluorine atom, a chlorine atom, a methyl group, a trifluoromethyl group, or a methoxy group; or Ra and Rb are bonded to each other to form a substituted or unsubstituted tetrahydroisoquinolinyl group or isoindolinyl group together with the ring on which they are substituted; either one of Rd and Re represents a methyl group, an ethyl group, a propynyl group, a cyclopropyl group, a trifluoroethyl group, a tert-butoxy group, or an ethyl group substituted with tert-butoxycarbonylamino, and the other represents a hydrogen atom or a methyl group; or NRdRe forms azepane; and n is 0.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 91.0
- Lexical Diversity: 1.375
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15203059', '15893804', '15023894', '13394525', '13796928']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8546502078723772
- 35 USC 102 Novelty (BERT): 0.5881989288271687
- Combined Prediction Score: 0.8280050799678563
- Mean Citation Score: 457.957174
- Max Citation Score: 524.8892
- Similarity Product: 438.88394090175626

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test