PATENT CLAIM ANALYSIS

Application Number: 15749168
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "325000"]

Abstract:
CRISPR/Cas Systems are provided where two or more guide RNAs having different spacer sequence lengths direct an enzymatically active Cas9 having a transcriptional regulator attached thereto to either cut a target nucleic acid or regulate expression of a target nucleic acid.

Claim (Index 3):
The method of  claim 1  wherein the enzymatically active Cas9 having a transcriptional regulator attached thereto is provided to the cell by introducing into the cell a first foreign nucleic acid encoding the enzymatically active Cas9 having a transcriptional regulator attached thereto and wherein the guide RNA is provided to the cell by introducing into the cell a second foreign nucleic acid encoding the guide RNA, wherein the first foreign nucleic acid and the second foreign nucleic acid are provided to the cell on the same or different vectors,\n wherein the guide RNA and the enzymatically active Cas9 having a transcriptional regulator attached thereto are expressed, \n wherein the guide RNA and the enzymatically active Cas9 having a transcriptional regulator attached thereto co-localize to the target nucleic acid.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.2
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14319289', '15049451', '14674895', '14903728', '14105017']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7196107209850107
- 35 USC 102 Novelty (BERT): 0.5765128518919236
- Combined Prediction Score: 0.705300934075702
- Mean Citation Score: 478.90802600000006
- Max Citation Score: 500.33353
- Similarity Product: 411.3495655478238

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test