PATENT CLAIM ANALYSIS

Application Number: 16000701
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "226500"]

Abstract:
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability, solubility, or pharmacokinetics of the NSAID for the treatment of conditions such as pain.

Claim (Index 1):
A method of improving dissolution of meloxicam in a stomach of a mammal, comprising orally administering a solid dosage form comprising both a bicarbonate and meloxicam to the mammal, wherein, at a designated time, the dissolution of meloxicam for the solid dosage form is improved as compared with a reference dosage form that: 1) contains the same amount of meloxicam; 2) does not contain the bicarbonate; and 3) does not contain a carbonate, wherein the rate of dissolution of meloxicam of the solid dosage form or the reference dosage form is determined by a dissolution test, wherein the dissolution test is: adding the dosage form or the reference dosage form to 500 mL of a 0.01 N HCl aqueous solution, stirring at 75 revolutions per minute (RPM) with a USP paddle apparatus II at 37\u00b0 C., and determining the amount of meloxicam dissolved in the 0.01 N HCl aqueous solution at the designated time.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 94.0
- Lexical Diversity: 1.39474
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15984055', '15988104', '15902770', '15986215', '15989734']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7870771092525577
- 35 USC 102 Novelty (BERT): 0.5345250791366248
- Combined Prediction Score: 0.7618219062409645
- Mean Citation Score: 342.537594
- Max Citation Score: 369.3147
- Similarity Product: 297.9417503627301

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test