PATENT CLAIM ANALYSIS

Application Number: 15949178
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "283100"]

Abstract:
Devices and methods generate an ordered restriction map of genomic DNA extracted from whole cells, nuclei, whole chromosomes, or other sources of long DNA molecules. The devices have a fluidic microchannel that merges into a reaction nanochannel that merges into a detection nanochannel at an interface where the nanochannel diameter decreases in size by between 50% to 99%. Intact molecules of DNA are transported to the reaction nanochannel and then fragmented in the reaction nanochannel using restriction endonuclease enzymes. The reaction nanochannel is sized and configured so that the fragments stay in an original order until they are injected into the detection nanochannel. Signal at one or more locations along the detection nanochannel is detected to map fragments in the order they occur along a long DNA molecule.

Claim (Index 7):
The system of  claim 1 , further comprising a nanofunnel residing between and connecting the first reaction nanochannel with the microfluidic inlet.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 91.0
- Lexical Diversity: 1.79221
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14771989', '14204211', '15446630', '14926595', '15568980']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6278741270988168
- 35 USC 102 Novelty (BERT): 0.5914958987719652
- Combined Prediction Score: 0.6242363042661317
- Mean Citation Score: 462.629984
- Max Citation Score: 498.09015
- Similarity Product: 465.7327576761156

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test