PATENT CLAIM ANALYSIS

Application Number: 15743349
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "04400A"]

Abstract:
The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the insulin-like growth factor binding protein, acid labile subunit (IGFALS) gene or the insulin-like growth factor 1 (IGF-1) gene, methods of using such double stranded RNAi agents to inhibit expression of an IGFALS gene or an IGF-1 gene, and methods of treating subjects having an IGF system-associated disorder.

Claim (Index 49):
The dsRNA agent of  claim 40 , wherein formula (III) is represented by formula (IIIc):\n sense: 5\u2032n p -N a -XXX-N b -YYY-N a -n q 3\u2032 antisense: 3\u2032n p\u2032 -N a\u2032 -X\u2032X\u2032X\u2032-N b\u2032 Y\u2032Y\u2032Y\u2032-N a\u2032 -n q\u2032 5\u2032\u2003\u2003(IIIc) wherein each N b  and N b \u2032 independently represents an oligonucleotide sequence comprising 1-5 modified nucleotides.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 86.0
- Lexical Diversity: 1.67442
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15399820', '14976261', '14947025', '14650128', '15670132']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7955248968317303
- 35 USC 102 Novelty (BERT): 0.5532728252973294
- Combined Prediction Score: 0.7712996896782903
- Mean Citation Score: 412.498488
- Max Citation Score: 416.99576
- Similarity Product: 324.2212263960648

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test