PATENT CLAIM ANALYSIS

Application Number: 15745441
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "026000"]

Abstract:
Provided herein are alpha2-selective Na,K-ATPase inhibitors and prodrugs thereof, characterized by having a cyclic moiety attached to a digoxin or digitoxin derivative, as well as uses thereof in lowering intraocular pressure and in treating glaucoma and heart conditions.

Claim (Index 1):
A compound represented by general Formula I: including any pharmaceutically acceptable salt, prodrug, hydrate, solvate, enantiomer and diastereomer thereof, and any mixtures thereof, wherein:\n X is H or OH; \n R is represented by general Formula II: \n A is a spacer moiety or a covalent bond; and B is a cyclic moiety; or B is selected from the group consisting of an alkylsulfonyl, an arylsulfonyl and a sulfonamide; or B is \u2014NR 1 R 2  wherein R 1  and R 2  are each independently H or a C 1 -C 4  alkyl provided that at least one of R 1  and R 2  is a C 1 -C4 alkyl.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.22857
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14913366', '15276479', '15326262', '13697302', '10911300']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7840116589449537
- 35 USC 102 Novelty (BERT): 0.5147029310738049
- Combined Prediction Score: 0.7570807861578389
- Mean Citation Score: 217.841656
- Max Citation Score: 302.30185
- Similarity Product: 220.81839671752755

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test