PATENT CLAIM ANALYSIS

Application Number: 15863498
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-07
Patent Classification: ["514", "183000"]

Abstract:
This invention describes the use of indane acetic acid derivatives which are dual PPAR delta/gamma agonists, and which penetrate the Blood Brain Barrier and achieve effective brain to plasma drug levels at non-toxic doses, for the treatment of neurodegenerative diseases including one or more of the following: Alzheimer's Disease (AD); Huntington's Disease (HD); Parkinson's Disease (PD); Amyotrophic Lateral Sclerosis (ALS); Frontal Temporal Dementia (FTD); Corticobasal Degeneration (CBD); Progressive Supranuclear Palsey (PSP); Dementia with Lewy Bodies (DLB); or Multiple Sclerosis (MS).

Claim (Index 12):
The method of treatment according to  claim 11  wherein the indane acetic acid which penetrates the blood brain barrier has a rat brain to plasma ratio of greater than 10% 12 hours after oral dosing.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 91.0
- Lexical Diversity: 1.50667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15774638', '15830675', '15484445', '14429101', '14897396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7776631375559779
- 35 USC 102 Novelty (BERT): 0.5180912367521345
- Combined Prediction Score: 0.7517059474755936
- Mean Citation Score: 249.04305400000004
- Max Citation Score: 259.62888
- Similarity Product: 147.99664606410025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test