PATENT CLAIM ANALYSIS

Application Number: 16246380
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["514", "259000"]

Abstract:
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R 1 , R 2 , R 3 , R 4 , R 5 , and n are as defined herein.

Claim (Index 1):
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein:\n  is a single bond or a double bond; \n R 1  and R 2  are independently H or halogen; \n R 3  is independently selected from: halogen, phenyl, and a 5- to 6-membered heteroaryl comprising carbon atoms and 1-4 heteroatoms selected from N, NR a , O, and S(O) p ; wherein said phenyl and heteroaryl are substituted with 0-3 R 3A ; \n each R 3A  is independently selected from: halogen, CN, \u2014(O) m \u2014(C 1 -C 6  alkyl substituted with 0-1 R 3B ), C 1 -C 6  haloalkyl, C 1 -C 6  haloalkoxy, R 3C , \u2014OR 3C , \u2014C(\u2550O)R 3D , NR 3E R 3F , \u2014C(\u2550O)NR 3E R 3F , \u2014NHC(\u2550O)R 3D , \u2014S(\u2550O) 2 R 3D , \u2014S(\u2550O) 2 NR 3E R 3F , \u2014NHS(\u2550O) 2 (C 1 -C 4  alkyl), and \u2014CR 3C R 3E R 3G ; \n R 3B  is independently selected from: OH, NR e R f , C 1 -C 4  alkoxy, \u2014C(\u2550O)NR e R f , \u2014S(\u2550O) 2 (C 1 -C 4  alkyl), \u2014NHC(\u2550O)(C 1 -C 4  alkyl), and a 5- to 6-membered heterocycloalkyl comprising carbon atoms and 1-2 heteroatoms selected from N, NR a , O, and S(O) p ; wherein said heterocycloalkyl is substituted with 0-2 R c ; \n each R 3C  is independently selected from: C 3 -C 6  cycloalkyl, phenyl, and a 4- to 7-membered heterocycle comprising carbon atoms and 1-4 heteroatoms selected from N, NR a , O, and S(O) p ; wherein each moiety is substituted with 0-2 R c ; \n each R 3D  is independently selected from: C 1 -C 4  alkyl and R 3C ; \n R 3E  and R 3G  are, at each occurrence, independently selected from: H and C 1 -C 4  alkyl; \n each R 3F  is independently selected from: H and C 1 -C 4  alkyl substituted with 0-1 R d ; \n R 4  is independently selected from: H, halogen and C 1 -C 4  alkyl; \n R 5  is independently selected from OH and C 1 -C 4  alkyl; \n each R a  is independently selected from: H, \u2192O, C 1 -C 4  alkyl substituted with 0-1 R b , \u2014C(\u2550O)H, \u2014C(\u2550O)(C 1 -C 4  alkyl), \u2014CO 2 (C 1 -C 4  alkyl), C 3 -C 6  cycloalkyl, and benzyl; \n R b  is independently selected from: halogen, OH and C 1 -C 4  alkoxy; \n each R c  is independently selected from: \u2550O, halogen, OH, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, C 1 -C 4  alkoxy, and C 1 -C 4  haloalkoxy; \n R d  is independently selected from: OH and NR e R f ; \n R e  and R f  are, at each occurrence, independently selected from: H and C 1 -C 4  alkyl; \n each p is independently selected from 0, 1 and 2; and \n m and n are, at each occurrence, independently selected from 0 and 1.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 99.0
- Lexical Diversity: 1.27907
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14977273', '15538348', '16311575', '16311621', '16012468']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7732511384834782
- 35 USC 102 Novelty (BERT): 0.6063783702709147
- Combined Prediction Score: 0.7565638616622218
- Mean Citation Score: 448.49072400000006
- Max Citation Score: 509.5315
- Similarity Product: 506.1250902534128

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test