PATENT CLAIM ANALYSIS

Application Number: 15746609
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["435", "189000"]

Abstract:
In some embodiments, the present invention a mutated FAD-GDHa protein, wherein the mutated FAD-GDHa protein is mutated from a wild-type first species to contain at least one point mutation, wherein the mutated FAD-GDHα protein comprises: P(X) n=8 X4(X) n=16 V(X) n=6 RN(X) n=3 YDXRPXCXGX 3 NNCMP(X) n=1 CP(X) n=2 A(X) n=1 Y(X) n=1 G(X) n=6 A(X) n=2 AG(X) n=6 AVV(X) n=3 E(X) n=8-9 A(X) n=2 Y(X) n=1 D(X) n=5 HRV(X) n=5 V(X) n=2 A(X) n=3 E(X) n=2 K(X) n=4 S(X) n=5 P(X) n=1 G(X) n=2 N(X) n=4 GRN(X) n=1 MDH(X) n=4 V(X) n=1 F(X n=6-7 W(X) n=1 GRGP(X) n=9 RDGXX 5 R(X) n=19 T(X) n=14 L(X) n=14 X 2 (X) n=1 X 1 (X) n=1 E(X) n=4 P(X) n=1 NR(X) n=3 S(X) n=4 D(X) n=2 G(X) n=7 Y(X) n=4 Y(X) n=32-35 , wherein each X represents a wild-type amino acid residue of the first species and n indicates the number of the wild-type amino acid residues of the first species represented by a respective parenthetical at that position, wherein: a) X 1  is selected from the group consisting of X, S, C, T, M, V, Y, N, P, L, G, Q, A, I, D, W, H, and E, wherein if X 1  is L, H or V, then X 2  is D; b) X 3  is selected from the group consisting of G, H, D, Y, S, and X; c) X 4  is selected from the group consisting of S and X; and d) X 5  is selected from the group consisting of S and X.

Claim (Index 14):
An enzyme electrode, configured to measure the amount of glucose in a physiological fluid, comprising the mutated FAD-GDH\u03b1 of  claim 1  immobilized onto the electrode, wherein the mutated FAD-GDH\u03b1 is configured to catalyze glucose in the physiological fluid and produce electrons that are transferred to the electrode thereby generating an electrical current, wherein the intensity of the electrical current is indicative of the level of glucose in the physiological fluid.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 86.0
- Lexical Diversity: 3.81982
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15532339', '14369646', '15748164', '10968317', '12250953']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5900040611601806
- 35 USC 102 Novelty (BERT): 0.6158365292436055
- Combined Prediction Score: 0.592587307968523
- Mean Citation Score: 321.41786799999994
- Max Citation Score: 633.2090000000002
- Similarity Product: 492.8103275235297

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test