PATENT CLAIM ANALYSIS

Application Number: 16106104
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "301000"]

Abstract:
The present invention is directed to 5-fluoro-C-(aryl or hetercyclyl)-glycoside derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by SGLT activity, more particularly dual SGLT1/2 activity.

Claim (Index 9):
A compound as in  claim 4 , wherein\n R 1  is selected from the group consisting of hydroxy-methyl- and 1R-hydroxy-ethyl-; R 2  is selected from the group consisting of hydrogen, hydroxy, methyl, hydroxy-methyl-, methoxy, ethoxy and tri-deutero-methoxy; R 3  is selected from the group consisting of hydrogen and methyl; R 4  is selected from the group consisting of chloro, methyl, ethyl and methoxy; alternatively, R 2  and R 3  or R 3  and R 4  are taken together with the carbon atoms to which they are bound to form 2,3-dihydro-furanyl; R 5  and R 6  are the same and are selected from the group consisting of hydrogen and deuterium;  is selected from the group consisting of 4-ethyl-phenyl, 4-ethoxy-phenyl, 4-(fluoro-methoxy)-phenyl, benzothien-2-yl, 3,4-dihydro-2H-quinolin-7-yl, 2,3-dihydro-benzo[b][1,4]dioxin-6-yl, 2,3-dihydrobenzo[b][1,4]oxathiin-6-yl, bicyclo[4.2.0]octa-1 (6),2,4-trien-3-yl, 5,6-dihydro-7H-thieno[3,2-b]pyran-2-yl-7-one, 5-cyano-6,7-dihydrothieno[3,2-c]pyridin-2-yl and 2,2,3,3-tetra-deutero-2,3-dihydrobenzo[b][1,4]dioxin-6-yl; provided that when   bicyclo[4.2.0]octa-1 (6),2,4-trien-3-yl, then R 2  and R 3  or R 3  and R 4  are taken together with the carbon atoms to which they are bound to form 2,3-dihydro-furanyl; provided further that when   is selected from the group consisting of 4-ethyl-phenyl, 4-ethoxy-phenyl and 4-(fluoro-methoxy)-phenyl, then R 2  and R 3  or R 3  and R 4  are taken together with the carbon atoms to which they are bound to form 2,3-dihydro-furanyl; provided further that when R 1  is \u2014CH 2 OH, R 2  is H, R 3  is H, R 4  is CI, R 5  is H and R 6  is H, then   is other than benzothien-2-yl; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 96.0
- Lexical Diversity: 1.08108
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14593071', '16059072', '16059074', '13634597', '14122836']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8360824975328494
- 35 USC 102 Novelty (BERT): 0.5279755132296127
- Combined Prediction Score: 0.8052717991025257
- Mean Citation Score: 351.143048
- Max Citation Score: 357.37866
- Similarity Product: 276.8264789612782

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test