PATENT CLAIM ANALYSIS

Application Number: 15746646
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["540", "527000"]

Abstract:
The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.

Claim (Index 10):
A compound of the following formula (I): wherein R is selected from the group consisting of substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C6-C20 aryl, substituted or unsubstituted 3- to 20-membered heteroaryl, substituted or unsubstituted C7-C25 alkyl-aryl, substituted or unsubstituted C1-C5 alkyl-3- to 20-membered heteroaryl, substituted or unsubstituted C3-C20 cycloalkyl, and substituted or unsubstituted 3- to 20-membered heterocyclic group; wherein the heteroaryl or heterocyclic group has 1 to 5 heteroatoms selected from the group consisting of N, O and S; the cycloalkyl or heterocyclic group may be a monocyclic, polycyclic, spiro or bridged ring structure; R a  is selected from (a) or (b): (a) OR\u2032; wherein R\u2032 is selected from the group consisting of Me and Et; or (b) N(R\u2033) 2 ; wherein each R\u2033 is independently selected from the group consisting of H, substituted or unsubstituted C6-C20 aryl, substituted or unsubstituted 3- to 20-membered heteroaryl, substituted or unsubstituted C7-C25 alkyl-aryl, substituted or unsubstituted C1-C5 alkyl-3- to 20-membered heteroaryl, substituted or unsubstituted C3-C20 cycloalkyl, and substituted or unsubstituted 3- to 20-membered heterocyclic group; wherein the heteroaryl or heterocyclic group has 1 to 5 heteroatoms selected from the group consisting of N, O and S; the cycloalkyl or heterocyclic group may be a monocyclic, polycyclic, spiro or bridged ring structure; R b  is selected from the group consisting of H, and C1-C6 alkyl; or R b  and R, together with adjacent nitrogen atom, form a substituted or unsubstituted 3- to 20-membered heteroaryl, or substituted or unsubstituted 3- to 20-membered heterocyclic group; and when R a  is selected from (a) and R\u2032 is H, R is naphthyl substituted by methyl; the term \u201csubstituted\u201d means that one or more hydrogen atoms on the group is substituted by a substituent selected from the group consisting of halogen, C1-C6 alkyl, halogenated C1-C6 alkyl, C1-C6 alkoxy, C6-C10 aryl, C6-C10 aryl-oxy, C2-C10 ester group (alkyl-COO\u2014), C2-C10 acyl-alkoxy (alkyl-OOC\u2014), C2-C10 acyl (alkyl-CO\u2014), C2-C10 acyl amino (alkyl/aryl-NHC(O)\u2014), \u2014COOH, nitro, cyano, hydroxy, amino, and amino substituted by one or two C1-C6 alkyl.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 86.0
- Lexical Diversity: 1.63043
- Patent Class: 540.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15505052', '15436608', '15504854', '13035640', '15566872']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7770570852918595
- 35 USC 102 Novelty (BERT): 0.5328994373891801
- Combined Prediction Score: 0.7526413205015916
- Mean Citation Score: 356.33223200000015
- Max Citation Score: 361.1353
- Similarity Product: 274.2669870010495

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test