PATENT CLAIM ANALYSIS

Application Number: 15752635
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "265100"]

Abstract:
Janus kinase 1 selective inhibitors and pharmaceutical use thereof are provided.

Claim (Index 4):
The compound according to  claim 3 , or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, wherein the compound of Formula 2 is\n 3-(4-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)piperidine-1-yl)-3-oxopropanenitrile; N-methyl-N-(1-(phenylsulfonyl)piperidine-4-yl)-7H-pyrrolo[2,3-d]pyrimidine-4-amine; 3-((4-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)piperidine-1-yl)sulfonyl)benzonitrile; (R)-3-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)piperidine-1-yl)-3-oxopropanenitrile; (R)-3-((3-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)piperidine-1-yl)sulfonyl)benzonitrile; 3-(((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)piperidine-1-yl)sulfonyl)benzonitrile; (R)-3-(3,3-dimethyl-4-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)pyrrolidine-1-yl)-3-oxopropanenitrile; (S)-3-(3,3-dimethyl-4-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)pyrrolidine-1-yl)-3-oxopropanenitrile; 3-(4-((7H-pyrrolo[2,3-d]pyrimidine-4-yl)oxy)piperidine-1-yl)-3-oxopropanenitrile; 3-((4-((7H-pyrrolo[2,3-d]pyrimidine-4-yl)oxy)piperidine-1-yl)sulfonyl)benzonitrile; 3-(3-(((7H-pyrrolo[2,3-d]pyrimidine-4-yl)oxy)methyl)piperidine-1-yl)-3-oxopropanenitrile; 3-((3-(((7H-pyrrolo[2,3-d]pyrimidine-4-yl)oxy)methyl)piperidine-1-yl)sulfonyl)benzonitrile; 3-((4aR,7aR)-1-(7H-pyrrolo[2,3-d]pyrimidine-4-yl)octahydro-6H-pyrrolo[3,4-b]pyridine-6-yl)-3-oxopropanenitrile; or 3-((4aS,7aS)-1-(7H-pyrrolo[2,3-d]pyrimidine-4-yl)octahydro-6H-pyrrolo[3,4-b]pyridine-6-yl)-3-oxopropanenitrile.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 88.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15507409', '14183946', '13928696', '14715046', '13859569']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7828071074675144
- 35 USC 102 Novelty (BERT): 0.5625824349397305
- Combined Prediction Score: 0.7607846402147359
- Mean Citation Score: 368.18293400000016
- Max Citation Score: 425.25983
- Similarity Product: 359.8307328207636

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test