PATENT CLAIM ANALYSIS

Application Number: 15759295
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["424", "649000"]

Abstract:
A DDS preparation of a platinum complex, which selectively releases a highly active platinum complex in cells that are under reducing conditions, and exhibits high antitumor activity that is required from a medicine, is still not available, and there is a demand for a novel DDS preparation of a platinum complex that may be used in clinical fields. There is provided a polymer conjugate of a hexa-coordinated platinum complex, the polymer conjugate comprising a block copolymer having a polyethylene glycol structural moiety and a polyaspartic acid moiety or a polyglutamic acid moiety; and a hexa-coordinated platinum complex having a halogen atom and a hydroxyl group at the axial positions, the hexa-coordinated platinum complex being bonded, directly or via a spacer, to a side-chain carboxyl group of the block copolymer.

Claim (Index 9):
The polymer conjugate of a hexa-coordinated platinum complex according to  claim 6 , wherein R 11  represents a methyl group; R 19  represents a trimethylene group; R 20  represents an acetyl group; R 21  represents a substituent selected from the group represented by the following Formula (X): [wherein W represents a substituent selected from the group consisting of a residue of a hexa-coordinated platinum complex having a halogen atom and a hydroxyl group at the axial positions, and \u2014NR 16 CONHR 17 ; R 16  and R 17  both represent a cyclohexyl group or an isopropyl group; T represents a hydrogen atom, a methyl group, an ethyl group, or a benzyl group; and R 8  represents a residue of an amino acid having the carboxylic acid protected], provided that at least one W among the substituents represents a residue of a hexa-coordinated platinum complex having a halogen atom and a hydroxyl group at the axial positions; R 22  represents \u2014NR 14 CONHR 15 ; and R 14  and R 15  both represent a cyclohexyl group or an isopropyl group.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 90.0
- Lexical Diversity: 1.84211
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15548259', '12312009', '13319175', '12226962', '12225230']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7894482901961707
- 35 USC 102 Novelty (BERT): 0.5178841616657599
- Combined Prediction Score: 0.7622918773431296
- Mean Citation Score: 282.07612200000005
- Max Citation Score: 302.37155
- Similarity Product: 209.60921873807308

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test