PATENT CLAIM ANALYSIS

Application Number: 15756014
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "329000"]

Abstract:
The present invention provides using a substituted 1-arylalkyl-4-acylaminopiperidine compound of Formula I: to treat various clinical conditions including, but not limited to, hemorrhagic shock, nicotine withdrawal symptoms, gastrointestinal side effects of opioids, cancer therapy, epithelial wounds, herpes zoster infection, or opioid-induced pruritus. In compound of Formula I, R 1  is C 1-10  alkyl, C 1-10  haloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; R 2  is C 1-6  alkylene; Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula —C(═O)—X 1 , wherein X 1  is —OR 3  or —NR 4 R 5 , where each of R 3 , R 4  and R 5  is H or C 1-10  alkyl.

Claim (Index 1):
A method for treating a clinical condition associated with \u03b1 2B  adrenoreceptor activation, said method comprising administering a therapeutically effective amount of an \u03b1 2B  adrenoreceptor antagonist to a patient in need of such a treatment, wherein said \u03b1 2B  adrenoreceptor antagonist is of the formula: wherein\n R 1  is C 1-10  alkyl, C 1-10  haloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; \n R 2  is C 1-6  alkylene; \n Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula \u2014C(\u2550O)\u2014X 1 , wherein X 1  is \u2014OR 3  or \u2014NR 4 R 5 , where each of R 3 , R 4  and R 5  is H or C 1-10  alkyl, \n and wherein said clinical condition associated with \u03b1 2B  adrenoreceptor activation is selected from the group consisting of hemorrhagic shock, nicotine withdrawal symptoms, gastrointestinal side effects of opioids, cancer therapy, epithelial wounds, herpes zoster infection, and opioid-induced pruritus.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 88.0
- Lexical Diversity: 1.76923
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14834185', '13017860', '12828800', '14047469', '13014314']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7242038389757826
- 35 USC 102 Novelty (BERT): 0.5051708820200701
- Combined Prediction Score: 0.7023005432802114
- Mean Citation Score: 238.6757
- Max Citation Score: 265.4231
- Similarity Product: 210.8922884056568

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test