PATENT CLAIM ANALYSIS

Application Number: 16195005
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["435", "325000"]

Abstract:
A method of obtaining a neural multipotent, unipotent or somatic cell, including: i) providing a cell of a first type which is not a neural multipotent, unipotent or somatic cell; ii) increasing expression of at least one neural multipotent or unipotent gene regulator in the cell of a first type, to a level at which the at least one neural multipotent or unipotent gene regulator is capable of driving transformation of the cell of a first type into the neural multipotent, unipotent or somatic cell, wherein the at least one multipotent or unipotent gene regulator is Musashi1 (Msi1), Neurogenin 2 (Ngn2), or both Msi1 and Ngn2; and iii) placing or maintaining the cell in a neural cell culture medium and maintaining sufficient intracellular levels of the at least one multipotent or unipotent gene regulator for a sufficient period of time to allow a stable neural multipotent, unipotent or somatic cell to be obtained.

Claim (Index 4):
The method of  claim 1 , wherein the cell of a first type is transfected with at least one expression vector encoding polypeptide(s) selected from the group consisting of Musashi1 (Msi1), Neurogenin 2 (Ngn2), and Msi1 and Ngn2.

Metadata:
- Claim Count in Document: 33.0
- Percentile: 98.0
- Lexical Diversity: 2.70312
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15297972', '15298006', '13504988', '15298034', '15275921']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8730029832789759
- 35 USC 102 Novelty (BERT): 0.7869796408642274
- Combined Prediction Score: 0.864400649037501
- Mean Citation Score: 982.044498
- Max Citation Score: 1064.8004
- Similarity Product: 975.3246804098608

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test