PATENT CLAIM ANALYSIS

Application Number: 16045358
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["544", "281000"]

Abstract:
This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Claim (Index 48):
The compound of  claim 1 , or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is C 1-6  alkyl; R 2  is C 1-6  alkoxy, phenyl, or monocyclic 5-6 membered heteroaryl; wherein said phenyl or monocyclic 5-6 membered heteroaryl of R 2  are each optionally substituted with 1, 2, or 3 independently selected R j  substituents; each R j  is independently selected from halo, CN, C 1-4  alkyl, C 1-4  haloalkyl, C 2-4  alkenyl, C 2-4  alkynyl, NHOR k , OR k , C(O)R k , C(O)NR k R k , C(O)OR k , OC(O)R k , OC(O)NR k R k , NHR k , NR k R k , NR k C(O)R k , S(O) 2 R k , NR k S(O) 2 R k , and S(O) 2 NR k R k ; each R k  is independently selected from H, C 1-4  alkyl, and C 1-4  haloalkyl; R 3a  is H, C 1-6  alkyl, C 2-6  alkynyl, C 3-7  cycloalkyl, phenyl-C 1-4  alkyl-, (5-6 membered heteroaryl)-C 1-4  alkyl, and (4-6 membered heterocycloalkyl)-C 1-4  alkyl; wherein said C 1-6  alkyl, C 3-7  cycloalkyl, phenyl-C 1-4  alkyl-, (5-6 membered heteroaryl)-C 1-4  alkyl, and (4-6 membered heterocycloalkyl)-C 1-4  alkyl of R 3a  are each optionally substituted by 1, 2, 3, or 4 independently selected R b  substituents; each R b  is independently selected from halo, C 1-4  alkyl, C 1-4  haloalkyl, CN, OH, NH 2 , NHOR c , OR c , C(O)R c , C(O)NR c R c , C(O)OR c , OC(O)R c , OC(O)NR c R c , NHR c , NR c R c , NR c C(O)R c , NR c C(O)OR c , NR c S(O)R, NR c S(O) 2 R c , S(O) 2 R c  and S(O) 2 NR c R c ; R 4a  is selected from H, C 1-6  alkyl, C 2-6  alkynyl, C 3-7  cycloalkyl, phenyl-C 1-4  alkyl-, and (5-6 membered heteroaryl)-C 1-4  alkyl-; wherein said C 1-6  alkyl, C 2-6  alkynyl, C 3-7  cycloalkyl, phenyl-C 1-4  alkyl-, and (5-6 membered heteroaryl)-C 1-4  alkyl- of R 4a  are each optionally substituted by 1, 2, 3, or 4 independently selected R b  substituents; R 3  is H or C 1-6  alkyl; R 4  is H or C 1-6  alkyl; R 5a  is H or C 1-6  alkyl; R 5  is H, halo, or C 1-6  alkyl; R 6  is halo, CN, or C 1-6  alkyl; and each R c  is independently H or C 1-6  alkyl; or any two R c  substituents together with the nitrogen atom to which they are attached form a 4-, 5-, 6-, or 7-membered heterocycloalkyl group optionally substituted with 1, 2, or 3 independently selected R h  substituents.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 95.0
- Lexical Diversity: 1.27778
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15343375', '15631417', '13085643', '13329532', '14872881']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8233783207964357
- 35 USC 102 Novelty (BERT): 0.6121513979581492
- Combined Prediction Score: 0.8022556285126071
- Mean Citation Score: 421.74511
- Max Citation Score: 495.84445
- Similarity Product: 452.9390445330024

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test