PATENT CLAIM ANALYSIS

Application Number: 16166359
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["424", "094500"]

Abstract:
The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia-lyase (PAL) polypeptides.

Claim (Index 6):
An engineered polynucleotide encoding an engineered polypeptide comprising an amino acid sequence having at least 90% sequence identity to reference sequence SEQ ID NO:12, wherein said amino acid sequence comprises a glycine at position 290, and wherein said engineered polypeptide further comprises at least one or more of the following substitutions or substitution sets selected from 18, 18/47, 18/47/214, 18/47/214/308, 18/47/214/308/450/546, 18/47/214/450, 18/47/214/467/540/546, 18/47/214/540, 18/47/214/546, 18/47/308/546, 18/47/450, 18/47/450/528/546, 18/47/450/546, 18/214, 18/214/308, 18/214/308/450/467, 18/214/450, 18/214/460, 18/214/467/546, 18/214/540, 18/450/540, 18/540, 47, 47/214, 47/214/308, 47/214/540, 47/214/546, 47/450, 59/134, 59/134/240/304/353/521/564, 59/134/240/353, 59/134/240/521, 59/134/240/521/564, 59/134/240/521/565, 59/134/304/353/521, 59/134/353/509/521, 59/134/509, 59/240, 59/240/353/509, 59/240/353/564/565, 59/240/509/521/564, 59/353, 59/353/509/564, 59/353/521, 59/353/565, 59/509/564, 59/521, 59/564, 134/240/304/353/564, 134/240/353/509/521/564, 134/240/353/521/564, 134/240/509/521, 134/304/353/521/565, 134/353/509/564, 134/353/521, 134/353/521/564, 134/353/564, 134/521, 214/308/460, 214/450/528, 214/540, 214/546, 240, 240/304/353/509/521/564, 240/304/509, 240/304/509/521, 240/353/509, 240/353/509/521, 240/353/509/521/564/565, 240/353/521, 240/509, 240/509/564/565, 240/509/565, 240/521/564/565, 304/353/509, 304/509, 308/450/467, 353/521, 521, and 528/546, wherein said positions in said amino acid sequence are in reference to SEQ ID NO:12.

Metadata:
- Claim Count in Document: 75.0
- Percentile: 97.0
- Lexical Diversity: 1.38095
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15431491', '15720198', '14255539', '15720060', '14688126']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8657158286772834
- 35 USC 102 Novelty (BERT): 0.7887796074385222
- Combined Prediction Score: 0.8580222065534072
- Mean Citation Score: 936.91942
- Max Citation Score: 1245.8074
- Similarity Product: 983.1122759114744

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test