PATENT CLAIM ANALYSIS

Application Number: 16211572
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["546", "210000"]

Abstract:
The present invention relates to tetrazolyl-containing cyclopropanecarboxamides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

Claim (Index 1):
A compound of general formula (I): in which A represents tetrazolyl which is attached to the rest of the molecule via the carbon atom; X represents CH, CR 6  or N; Z represents OR 1  or NR 2 R 3 ; R 1  represents C 1 -C 7 -alkyl, C 3 -C 7 -cycloalkyl, 4- to 7-membered heterocycloalkyl, (4- to 7-membered heterocycloalkyl)-C 1 -C 4 -alkyl, phenyl or 5- or 6-membered heteroaryl, wherein said C 1 -C 7 -alkyl is optionally substituted, one or more times, independently from each other, with C 1 -C 4 -alkoxy and said C 3 -C 7 -cycloalkyl, 4- to 7-membered heterocycloalkyl, (4- to 7-membered heterocycloalkyl)-C 1 -C 4 -alkyl, phenyl or 5- or 6-membered heteroaryl groups are optionally substituted, one or more times, independently from each other, with C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; R 2 , R 3  represent, independently from each other, hydrogen, C 1 -C 7 -alkyl, C 3 -C 7 -cycloalkyl, 4- to 7-membered heterocycloalkyl, C 3 -C 7 -cycloalkyl-C 1 -C 4 -alkyl, (4- to 7-membered heterocycloalkyl)-C 1 -C 4 -alkyl, phenyl or 5- or 6-membered heteroaryl, wherein said C 1 -C 7 -alkyl is optionally substituted, one or more times, independently from each other, with C 1 -C 4 -alkoxy and said C 3 -C 7 -cycloalkyl, 4- to 7-membered heterocycloalkyl, C 3 -C 7 -cycloalkyl-C 1 -C 4 -alkyl, (4- to 7-membered heterocycloalkyl)-C 1 -C 4 -alkyl, phenyl or 5- or 6-membered heteroaryl groups are optionally substituted, one or more times, independently from each other, with C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy, or\n R 2  and R 3  together with the nitrogen atom to which they are attached form a 5- to 6-membered heterocyclic ring, optionally containing one additional heteroatom selected from O and N and optionally substituted with C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; \n R 4  represents C 1 -C 4 -alkyl or halogen; \n R 5a  represents hydrogen, phenyl or heteroaryl;\n wherein said phenyl or heteroaryl groups are optionally substituted, one or more times, independently from each other, with halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; \n \n R 5b  represents hydrogen, phenyl or heteroaryl;\n wherein said phenyl or heteroaryl groups are optionally substituted, one or more times, independently from each other, with halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy and \n wherein one of R 5a  and R 5b  represents hydrogen and the other represents phenyl or heteroaryl; \n \n R 6  represents C 1 -C 3 -alkyl or halogen; \n n represents 0, 1 or 2; \n and stereoisomers, tautomers, N-oxides, hydrates, solvates, and salts thereof, and mixtures of same.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 98.0
- Lexical Diversity: 1.42553
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15534855', '16192314', '15575235', '15820429', '15106073']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7462307300033026
- 35 USC 102 Novelty (BERT): 0.5250080999568334
- Combined Prediction Score: 0.7241084669986557
- Mean Citation Score: 312.8146720000001
- Max Citation Score: 320.64386
- Similarity Product: 235.9548358818102

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test