PATENT CLAIM ANALYSIS

Application Number: 16136953
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["424", "210100"]

Abstract:
The present application discloses methods for removing residual impurities from protein preparations. Such methods include addition of an anionic detergent to a solution comprising proteins of interest and cellular contaminants under non-precipitating conditions and passing the solution through an ion exchange column.

Claim (Index 2):
A method for removing residual cellular DNA from a sample comprising viral protein, the method comprising the steps of:\n a. providing a sample comprising virus grown in a host cell system, wherein the virus expresses viral protein of interest; b. splitting the virus; c. adding an anionic detergent to a solution comprising the viral proteins under non-precipitating conditions; and, d. passing the solution through an ion exchange matrix, whereby residual cellular DNA is bound to the ion exchange resin, so as to obtain an eluate comprising the viral protein of interest.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.15789
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12199977', '14593337', '12092190', '12756590', '14699213']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.677165631444127
- 35 USC 102 Novelty (BERT): 0.5028900849569576
- Combined Prediction Score: 0.6597380767954101
- Mean Citation Score: 255.25755
- Max Citation Score: 261.4888
- Similarity Product: 189.6541987801552

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test