PATENT CLAIM ANALYSIS

Application Number: 15909088
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "156000"]

Abstract:
Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.

Claim (Index 1):
A compound of Formula 1a or 1b, or a pharmaceutically acceptable salt thereof: wherein, R 1a  to R 1d  are each independently hydrogen, a halogen, C 1-6  alkyl, C 1-6  haloalkyl, hydroxyalkyl, C 1-6  alkoxy, C 1-6  haloalkoxy, C 2-10  alkenyl, C 2-10  haloalkenyl, C 2-10  alkynyl, C 2-10  haloalkynyl, a hydroxyl group, nitro, cyano, C 1-6  alkoxycarbonyl, amino, C 1-6  alkylamino, alkyl)amino, amino(C 1-6 )alkyl, (C 1-6 )alkylamino(C 1-6 )alkyl, C 1-6  alkanoyl, C 3-7  cycloalkyl, an aryl, a heterocycle, or a heteroaryl, wherein R 1a  to R 1d  are each independently unsubstituted or optionally substituted; R 2  is hydrogen, C 1-6  alkyl, (C 1-6 )alkoxy(C 1-6 )alkyl, C 1-6  haloalkyl, C 1-6  hydroxyalkyl, C 1-6  alkoxy, C 1-6  haloalkoxy, C 2-10  alkenyl, C 2-10  alkenyl carboxy, C 2-10  haloalkenyl, C 2-10  alkynyl, C 2-10  haloalkynyl, a hydroxyl group, nitro, cyano, C 1-6  alkoxycarbonyl, amino, C 1-6  alkylamino, C 1-6  cyanoalkyl, alkyl)amino, amino(C 1-6 )alkyl, (C 1-6 )alkylamino(C 1-6 )alkyl, C 1-6  alkanoyl, C 3-7  cycloalkyl, (C 1-6 )alkyl(C 3-7 )cycloalkyl, aryl, (C 1-6 )alkylaryl, (C 1-6 )haloalkylaryl, (C 2-6 )alkenylamide(C 1-6 )alkylalkoxy, a heterocycle, (C 1-6 )alkylheterocycle, a heteroaryl, or (C 1-6 )alkylheteroaryl, wherein R 2  is unsubstituted or optionally substituted; R 3  is C 1-4  alkyl, isoalkyl, cycloalkyl, phenyl, or C 1-4  haloalkyl; n is an integer from 0 to 2; and Y is hydrogen, an alkyl, a haloalkyl, \u2014C(O)alkyl, \u2014C(O)aryl, a sulfonylalkyl, a sulfonylaryl, an aryl, or an alkylaryl, wherein an alkyl has 1 to 10 carbon atoms, and an aryl is unsubstituted or optionally substituted, with the proviso that: i) a compound of Formula 1a or 1 b having one or more of R 1a  to R 1d  being halogen, R 3  being C 1-4  alkyl, isoalkyl, cycloalkyl, phenyl or C 1-4  haloalkyl, and R 2  being C(R 4a )(R 4b )aryl wherein R 4a  and R 4b  being C 1-4  alkyl, halogen or C 1-4  cycloalkyl; and ii) a compound of Formula 1a or 1b having R 1a  to R 1c  being hydrogen, R 1d  being fluorine, n being 0, m being 1, Y being hydrogen, R 3  being C 1  alkyl, and R 2  being benzyl, are excluded.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 90.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11208437', '15663179', '15586343', '14647521', '11015348']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.805476145063494
- 35 USC 102 Novelty (BERT): 0.5208007861297456
- Combined Prediction Score: 0.7770086091701192
- Mean Citation Score: 314.747628
- Max Citation Score: 325.22043
- Similarity Product: 296.41511415415414

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test