PATENT CLAIM ANALYSIS

Application Number: 15985060
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "001900"]

Abstract:
The invention provides a conjugate comprising a biomolecule linked to a fatty acid via a linker wherein the fatty acid has the following Formulae A1, A2 or A3: wherein R 1 , R 2 , R 3 , R 4 , Ak, n, m and p are defined herein. The invention also relates to a method for manufacturing the conjugate of the invention such as GDF15 conjugate, and its therapeutic uses such as treatment or prevention of metabolic disorders or diseases, type 2 diabetes mellitus, obesity, pancreatitis, dyslipidemia, alcoholic and nonalcoholic fatty liver disease/steatohepatitis and other progressive liver diseases, insulin resistance, hyperinsulinemia, glucose intolerance, hyperglycemia, metabolic syndrome, hypertension, cardiovascular disease, atherosclerosis, peripheral arterial disease, stroke, heart failure, coronary heart disease, diabetic complications (including but not limited to chronic kidney disease), neuropathy, gastroparesis and other metabolic disorders. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Claim (Index 11):
The method according to  claim 1 , wherein the biomolecule is MH(199-308)hGDF15, MHA(200-308)hGDF15, AHA(200-308)hGDF15, AH(199-308)GDF15, MHHHHHHM-hGDF15 or MHHHHHH-hGDF15; or a dimer thereof.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 93.0
- Lexical Diversity: 1.74038
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14738272', '14336262', '14996418', '14905338', '14905333']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.815059110434247
- 35 USC 102 Novelty (BERT): 0.59359037911851
- Combined Prediction Score: 0.7929122373026734
- Mean Citation Score: 305.8291240000001
- Max Citation Score: 509.15088
- Similarity Product: 424.4786947663879

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test