PATENT CLAIM ANALYSIS

Application Number: 15751709
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "171000"]

Abstract:
Compositions comprising S1P receptor modulators and at least one compound selected from one or more of the group consisting of steroids, opioids and non-steroidal anti-inflammatory drugs are provided. The compositions find use in the treatment of disease, particularly inflammation and immune mediated disorders.

Claim (Index 2):
A composition according to  claim 1 , wherein the at least one S1P receptor modulator is a compound of formula (I): wherein R 1  is selected from hydrogen, deuterium, halogen, CN, CF 3 , \u2014COOH, amide, sulphonamide, aryloxy, nitro and an alkyl chain (C 1-5 ), said alkyl chain optionally containing one or more of deuterium, O, S, NR\u2032 (R\u2032 \u2550H, alkyl, cycloalkyl), halogen, a multiple bond, heterocycle, aryl, cycloalkyl (C 3-7 ) and carbocycle; wherein R 2  is selected from hydrogen, deuterium, halogen, CN, CF 3 , an alkyl chain (C 1-4 ) said alkyl chain optionally containing one or more of deuterium, O, S, NR\u2032 (R\u2032 \u2550H, alkyl, cycloalkyl), halogen, a multiple bond, heterocycle, aryl or cycloalkyl (C 3-7 ) and carbocycle; wherein R 3  is selected from hydrogen, deuterium, halogen, an alkyl chain (C 1-7 ) said alkyl chain optionally containing one or more of deuterium, O, S, NR\u2032 (R\u2032 \u2550H, alkyl, cycloalkyl), halogen, a multiple bond, heterocycle, aryl or cycloalkyl (C 3-7 ) and carbocycle; wherein R 4  is selected from hydrogen, deuterium, halogen, CN, CF 3 , an alkyl chain (C 1-4 ) said alkyl chain optionally containing one or more of deuterium, O, S, NR\u2032 (R\u2032 \u2550H, alkyl, cycloalkyl), halogen, a multiple bond, heterocycle, aryl and cycloalkyl (C 3-7 ); wherein A is optional and when present is selected to replace one or more ring carbon atoms by N; wherein L is selected from hydrogen, deuterium, F, Cl, Br and alkyl (C 1-3 ); wherein G is a group selected from one of the following: wherein R is selected from H, COOH, alkyl (C 1-4 ) and hydroxy-alkyl (C 1-4 ); wherein R\u2032 and R\u2033 are independently selected from H and alkyl (C 1-4 ); wherein R\u2032\u2033 is selected from OH, \u2014OPO 3 H 2  and physiologically acceptable salts; wherein represents an optional bridging group;\n the asterisks indicating the attachment of group G within formula (I).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 88.0
- Lexical Diversity: 1.20513
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12176279', '12119311', '12913363', '12978087', '13604152']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7661237926539205
- 35 USC 102 Novelty (BERT): 0.4806781515877719
- Combined Prediction Score: 0.7375792285473057
- Mean Citation Score: 188.709352
- Max Citation Score: 193.54948
- Similarity Product: 147.51173836453913

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test