PATENT CLAIM ANALYSIS

Application Number: 15959419
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-09
Patent Classification: ["514", "232800"]

Abstract:
Disclosed are a compound represented by Formula (1), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, tautomer, enantiomer, or pharmaceutically acceptable diastereomer thereof, a method of preparing the same, and a pharmaceutical composition, which have effects for treatment or prevention of metabolic syndromes, comprising the same: wherein R 1  to R 6 , X 1  to X 4 , and n are the same as defined in claim  1.

Claim (Index 26):
A method of preparing the compound of Formula (1) according to claim  1 , the method comprising:\n A 3 ) reacting the compound of Formula (5) with Z\u2032Z, where Z\u2032 is C 6 H 5 CH 2 \u2014, CH 3 OC 6 H 4 CH 2 \u2014 or \u2014CH 3 \u2014 and Z is a halogen; B 3 ) reducing \u2014NO 2  to \u2014NH 2  through reduction of the compound generated in the reacting (A 3 ); C 3 ) introducing \u2014NO 2  by reacting the compound generated in the reducing (B 3 ) with HNO 3  under acidic conditions and then reducing \u2014NO 2  to \u2014NH 2  through reduction; D 3 ) reacting the compound generated in the introducing (C 3 ) with R 4 COOH, (R 4 ) 2 O, carbonyldiimidazole (CDI), (CH 2 ) n \u2032, (COOH) 2 , or (R 4 ) 4 C, where R 4  is the same as defined in claim  1  and n\u2032 is an integer of 0 or more; E 3 ) reducing after selectively cyclizing the compound generated in the reacting (D 3 ) under acidic conditions and selectively reacting with R 10 R 11 NH; and F 3 ) generating a final product through oxidation of the compound generated in the reducing (E 3 ), the compound of Formula (5) is the same as defined in  claim 10 , R 10  and R 11  are each independently hydrogen, a halogen, or substituted or unsubstituted C1-C5 alkyl or R 8  and R 9  form a ring structure of substituted or unsubstituted C4-C10 heterocycloalkyl through coupling, or a ring structure of substituted or unsubstituted C4-C10 heteroaryl, wherein a heteroatom is at least one selected from the group consisting of N, O, and S and a substituted group is methyl, ethyl or propyl.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 91.0
- Lexical Diversity: 1.61538
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15102968', '11849230', '12946759', '13035640', '13138227']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7403037279195709
- 35 USC 102 Novelty (BERT): 0.6024810027376997
- Combined Prediction Score: 0.7265214554013837
- Mean Citation Score: 370.249616
- Max Citation Score: 649.2651
- Similarity Product: 416.4836677764058

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test