PATENT CLAIM ANALYSIS

Application Number: 15946066
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "466000"]

Abstract:
Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or unsubstituted indol or a substituted or unsubstituted pyrrole, in the presence of a metal-containing catalyst, for a time and at a temperature to cause an annulation/arylation cascade reaction that yields a diindolylmethane or a indolyl/pyrrolylmethane. The resulting compounds are effective to modulate activity of arylhydrocarbon receptors, to inhibit activity of PCSK9, and to stimulate secretion of glucagon-like peptide 1 in mammals.

Claim (Index 10):
The pharmaceutical composition of  claim 7 , wherein at least one of R, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 3 \u2032, R 4 \u2032, R 5 \u2032, R 6 \u2032, and R 7 \u2032 is not hydrogen.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 91.0
- Lexical Diversity: 1.66129
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14818960', '14239541', '14111991', '14977011', '15541875']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7846319860481302
- 35 USC 102 Novelty (BERT): 0.5838156001055266
- Combined Prediction Score: 0.7645503474538698
- Mean Citation Score: 344.059252
- Max Citation Score: 563.0151
- Similarity Product: 378.2446953127742

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test