PATENT CLAIM ANALYSIS

Application Number: 16006374
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "064000"]

Abstract:
The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: R 1  is H or CH 3  R 2  is not H, and is CH 3 , or C1-C6 straight chain, or branched alkyl, or C3-C6 cycloalkyl group, or unsaturated alkenyl, including C═CH 2 ; R 3  is H, CH 3 , or a C1-C6 alkyl or cycloalkyl group, a heteroatom-substituted alkyl; and R 4  is a C1 to C6 alkyl, or substituted alkyl group, especially including substituents which possess positive charge, or a hydroxyl group; or R 4  is an SR a , where R a  is an unsubstituted C1 to C6 alkyl group, a substituted C1 to C6 alkyl group, or a functional group that is positively charged, or which bears a positive charge when in aqueous solution at pH 7; or R 4  is a CH 2 OR b , where R b =C1 to C6 alkyl or substituted alkyl groups, substituted or unsubstituted aryl, or a heteroaryl groups.

Claim (Index 31):
The method of  claim 30 , further comprising adding a beta-lactamase inhibitor, clavulanic acid or avibactam (or related DBOs), or a boronic acid based beta-lactamase inhibitor.

Metadata:
- Claim Count in Document: 77.0
- Percentile: 94.0
- Lexical Diversity: 2.55263
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10572742', '14766826', '10311282', '12195706', '13550366']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7428023518679508
- 35 USC 102 Novelty (BERT): 0.5222486138758254
- Combined Prediction Score: 0.7207469780687383
- Mean Citation Score: 279.07053800000006
- Max Citation Score: 295.82526
- Similarity Product: 198.2822580224776

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test