PATENT CLAIM ANALYSIS

Application Number: 15974183
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "069600"]

Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A, IL-17F, and IL-23. Antagonists include antibodies and antibody fragments that bind IL-23 and that bind IL-17A or IL-17F, such as antibodies that are cross-reactive for IL-17A and Il-17F. Antagonists that include an antibody or antibody fragment that binds IL-23 and an antibody or antibody fragment that binds IL-17A or IL-17F on one molecule are also disclosed. Antibodies and antibody fragments that bind IL-23 and IL-17F but that do not bind IL-17A are also disclosed. IL-17 and IL-23 are cytokines that are involved in inflammatory processes and human disease.

Claim (Index 3):
A method of treating an inflammatory disease in a human patient comprising subcutaneously or intravenously administering to the patient a therapeutically effective amount of a composition comprising a bispecific antibody and a pharmaceutically acceptable carrier or diluent, wherein the bispecific antibody comprises a cross-reactive IL-17A and IL-17F binding entity and an IL-23p19 binding entity, wherein the cross-reactive IL-17A and IL-17F binding entity comprises a humanized antibody derived from the antibody produced by the hybridoma deposited with the American Type Culture Collection having the ATCC Patent Deposit Designation PTA-7988, wherein the IL-23p19 binding entity comprises an antibody which specifically binds to the p19 subunit of IL-23, and wherein the inflammatory disease is psoriasis or psoriatic arthritis.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 2.15094
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15260059', '13929226', '14626959', '13534019', '12111117']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6373059151850624
- 35 USC 102 Novelty (BERT): 0.5505871371058133
- Combined Prediction Score: 0.6286340373771375
- Mean Citation Score: 398.789452
- Max Citation Score: 404.65292
- Similarity Product: 385.7644800713086

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test