PATENT CLAIM ANALYSIS

Application Number: 16078696
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "019600"]

Abstract:
A method of treating acute myeloid leukemia (AML), including the steps of (i) measuring a density of blast cells in the peripheral blood and the bone marrow of a subject with AML; (ii) administering to the subject a CXCR4 antagonist; and (iii) administering to the subject a therapeutically effective amount of the CXCR4 antagonist and a therapeutically effective amount of a chemotherapeutic agent, if the blast cell density in the peripheral blood is less than 10% of the total peripheral white blood cells, or at least five-fold lower than the blast cell density in the bone marrow, or at least two-fold higher one day or more following step (ii).

Claim (Index 21):
A method of treating AML, the method comprising:\n (a) identifying a subject with AML having a density of blast cells in the peripheral blood being at least five-fold lower than the density of blast cells in the bone marrow; and (b) administering to said subject a therapeutically effective amount of a CXCR4-antagonist and a therapeutically effective amount of a chemotherapeutic agent, thereby treating the AML.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 2.04839
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13360751', '12520699', '14395842', '13378061', '11915428']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7836891547035242
- 35 USC 102 Novelty (BERT): 0.5458792573220419
- Combined Prediction Score: 0.7599081649653759
- Mean Citation Score: 392.619528
- Max Citation Score: 431.59787
- Similarity Product: 263.7013342165244

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test