PATENT CLAIM ANALYSIS

Application Number: 15754807
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "216100"]

Abstract:
A dry powder norovirus vaccine is provided, which comprises at least two norovirus antigens representing different genogroups. The vaccine may be produced by formulation with a mixture of different antigens or combination of monovalent powders with each containing one antigen. The formulated vaccine is suitable for mucosal administration and soluble in aqueous solutions for parenteral administration. A method of immunization is also provided, which comprises at least one administration of the vaccine via mucosal and/or parental route. The immunization may have multiple administrations of the vaccine, i.e., one or more immunizations via a mucosal route followed by one or more immunizations via a parenteral route or vice versa, to maximize both mucosal and systemic immune responses and protection against norovirus infections.

Claim (Index 62):
A method for producing a multivalent dry powder norovirus vaccine composition suitable for both parenteral and mucosal routes of administration comprising:\n a. obtaining a first solution comprising a norovirus virus-like particle (VLP) antigen of GI genotype; b. introducing to the first solution, an anionic polysaccharide; c. drying the first solution with the anionic polysaccharide to a substantially non-aqueous state, thereby producing a first dry powder formulation; d. obtaining a second solution comprising a norovirus VLP antigen of GII genotype; e. introducing to the second solution an anionic polysaccharide; f. drying the second solution with the anionic polysaccharide to a substantially non-aqueous state, thereby producing a second dry powder formulation; g. combining the first and second dry powder formulations to form a multivalent dry powder norovirus vaccine formulation.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 88.0
- Lexical Diversity: 1.79452
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14796614', '13840403', '15836030', '14796714', '13837653']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7730993350363683
- 35 USC 102 Novelty (BERT): 0.5998927866030295
- Combined Prediction Score: 0.7557786801930344
- Mean Citation Score: 539.3485860000002
- Max Citation Score: 562.9781
- Similarity Product: 441.0062721042276

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test