PATENT CLAIM ANALYSIS

Application Number: 15933619
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["424", "140100"]

Abstract:
Disclosed is a method for treating of Cockayne Syndrome (CS). Specifically, the invention pertains to a method for the extracorporeal treatment of a body fluid by removing the body fluid from a living body diseased with CS, and applying a targeted antibody conjugated to a moiety to at least one Cockayne Syndrome antigen in the body fluid, creating an antibody-antigen moiety complex, removing antibody-antigen moiety complex from the body fluid, and returning the purified body fluid to the body.

Claim (Index 2):
The method of  claim 1  wherein the CSTA is at least one member selected from the group consisting of:\n death-associated protein 1 (DAP1), calpain, p21, mammalian target of rapamycin (mTOR), insulin growth factor-1 (IGF-1), lipofuscin, p16 (p16INK4a), cyclin-dependent kinase inhibitor 2A (CDKN2A), Senescence associated \u03b2-gal (SA-\u03b2-gal), promyelocytic leukemia (PML) protein, transforming growth factor \u03b2 (TGF-\u03b2), interleukin-6 (IL-6), indoleamine 2,3-dioxygenase, soluble tumor necrosis factor-receptor 55 (sTNF-R55), soluble tumor necrosis factor-receptor 75 (sTNF-R75), Progerin, oxygen and nitrogen based free radicals: (superoxide, nitric oxide, hydroxyl radical, perioxynitrite, nitrosoperoxycarbonate, hydrogen peroxide, hypochlorite); malondialdehyde (MDA, propanedial); tumor necrosis factor-\u03b1 (TNF-\u03b1), and mitogen activated protein kinases (MAPK).

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 1.91304
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15647850', '14978910', '09562245', '13254855', '10461885']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7008776173399601
- 35 USC 102 Novelty (BERT): 0.4749624778241116
- Combined Prediction Score: 0.6782861033883752
- Mean Citation Score: 130.47465
- Max Citation Score: 132.54641999999998
- Similarity Product: 94.1569930286765

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test