PATENT CLAIM ANALYSIS

Application Number: 16092680
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["530", "324000"]

Abstract:
The present invention is in the field of medicine and provides means and methods for the treatment, prevention or amelioration of osteoarthritis. More in particular, it provides a peptide for use in the treatment, amelioration or prevention of osteoarthritis, wherein the peptide consists of an amino acid sequence according to SEQ ID NO: 18 or an analogue thereof, wherein the analogue is a peptide consisting of an amino acid sequence according to formula 1 (SEQ ID NO: 29), or a fragment thereof wherein the fragment consists of at least 10 consecutive amino acids of SEQ ID NO: 18 or an amino acid sequence according to formula 1.

Claim (Index 5):
The method according to  claim 4 , wherein the variant according to SEQ ID NO: 33 comprises 12, 11, 10, 9, 8, 7, 6, 5, 4, 3, 2 or 1 amino acid substitution(s) selected from the group consisting of substitutions Z1, Z2, Z3, Z4, Z5, Z6, Z7, Z8, Z9, Z10, Z11, Z12 and Z13, wherein;\n Z1=A or I or L or M or Y or V or E or H or K or Q or R, Z2=P or Y or M, Z3=E or R or H or K or N or P or Q or S or T or I or L or M or V, Z4=A or E or Q or R or S, Z5=Y or N or D, Z6=E or A or Q, Z7=A or D or E or H or K or S, Z8=F or A or D or E or H or Q or R or S, Z9=P or M, Z10=N or A or D or S or T or E or Q or R or I or V, Z11=S or A or D or E or H or K or N or P or Q or T, Z12=Y or H or D or G or H or N or R or S or T or wherein Z13=N or F or W or Y or H or K or R.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 2.22222
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16092671', '12932876', '12012521', '12774293', '12211385']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7326627222459389
- 35 USC 102 Novelty (BERT): 0.6242431409705627
- Combined Prediction Score: 0.7218207641184012
- Mean Citation Score: 350.589832
- Max Citation Score: 615.9391
- Similarity Product: 527.6212078978122

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test