PATENT CLAIM ANALYSIS

Application Number: 15907263
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["702", "019000"]

Abstract:
A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline. Additionally, a second integrated circuit is also provided, where each second integrated circuit forming a field programmable gate array (FPGA), the FPGA being configured by firmware to arrange a set of hardwired digital logic circuits that are interconnected by a plurality of physical interconnects to perform a second set of genomic processing steps of the sequence analysis pipeline, the set of hardwired digital logic circuits of each FPGA being arranged as a set of processing engines to perform the second set of genomic processing steps. A shared memory is also provided.

Claim (Index 20):
The integrated circuit in accordance with  claim 19 , wherein the reconfigurable hardwired digital logic circuits are further arranged as a second set of processing engines, the second set of processing engines comprise an HMM module, the HMM module configured to:\n receive both the extracted candidate haplotype sequence and the read of genomic data; construct a computational matrix, the computational matrix comprising a first axis and a second axis, the first axis comprising the extracted candidate haplotype sequence, and the second axis comprises the read of genomic data, the computational matrix for comparing the sequence of nucleotides of the read of genomic data to the sequence of nucleotides of the extracted candidate haplotype sequence; and traverse a pathway through the computational matrix by performing an HMM calculation using the input values for each of the computational cells in the pathway to thereby determine a final probability of observing the sequence of the read of genomic data assuming the extracted candidate haplotype sequence is a true representation of the subject's genetic sequence.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 88.0
- Lexical Diversity: 2.40506
- Patent Class: 702.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15497149', '15059221', '15643381', '15094939', '15700018']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2921958611928763
- 35 USC 102 Novelty (BERT): 0.5721455351227935
- Combined Prediction Score: 0.3201908285858681
- Mean Citation Score: 430.74245
- Max Citation Score: 477.48706
- Similarity Product: 395.3626767991328

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test