PATENT CLAIM ANALYSIS

Application Number: 16053470
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-01
Patent Classification: ["530", "397000"]

Abstract:
A method for purifying rHuEPO through the use of a multi-step filtration process which provides for a rHuEPO product having superior stability and shelf-life.

Claim (Index 1):
A recombinant human erythropoietin alpha product having a shelf life of at least four years manufactured by the following process wherein the process comprises the following steps:\n a. manufacturing a recombinant human erythropoietin alpha product and collecting the supernatant, b. clarifying the supernatant and subjecting the supernatant to a multi-step purification process comprising the following procedures in order: ultradiafiltration, anion exchange chromatography, ammonium sulfate precipitation, hydrophobic interaction chromatography, acetonitrile addition, reversed phase chromatography, a second anion exchange chromatography step, gelfiltration, and nano filtration for virus removal; and c. producing a recombinant human erythropoietin alpha product that is substantially free of non-O-glycosylated recombinant human erythropoietin alpha isoforms.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.13636
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14775248', '12997292', '11977851', '09723955', '13168913']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6259234511683468
- 35 USC 102 Novelty (BERT): 0.5644824706822252
- Combined Prediction Score: 0.6197793531197346
- Mean Citation Score: 224.398474
- Max Citation Score: 473.2032
- Similarity Product: 355.55783031463613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test