PATENT CLAIM ANALYSIS

Application Number: 15873079
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["424", "450000"]

Abstract:
Docetaxel and doxorubicin can be formulated in liposomal pharmaceutical compositions. In various embodiments, the pharmaceutical compositions include (i) a first liposome type comprising a first lipid layer comprising an unsaturated phospholipid, cholesterol or a cholesterol derivative, DC-cholesterol, a cationic lipid, and preferably a pegylated phospholipid, and a first active pharmaceutical ingredient (API) comprising docetaxel in the first lipid layer; and (ii) a second liposome type comprising a second lipid layer, an aqueous interior, and a second API comprising doxorubicin crystallized in the aqueous interior, (iii) where the first liposome type does not comprise doxorubicin and the second liposome type does not comprise docetaxel. The pharmaceutical composition can be used to treat a subject, for example, a human subject having cancer. The cancer can be, for example, a lung cancer, preferably non-small cell lung cancer (NSCLC), colon cancer, breast cancer, or liver cancer, preferably hepatocellular carcinoma (HCC).

Claim (Index 22):
The pharmaceutical composition of  claim 1 , wherein both the first and second lipid layers comprise:\n about 20-75% (molar) unsaturated phospholipid; about 10-60% (molar) cholesterol; about 1-10% (molar) pegylated phospholipid; and about 5-75% (molar) cationic lipid.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 86.0
- Lexical Diversity: 2.47945
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15059972', '15221832', '14208297', '14765620', '15320903']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7240562481791069
- 35 USC 102 Novelty (BERT): 0.6732899641132977
- Combined Prediction Score: 0.7189796197725259
- Mean Citation Score: 417.138628
- Max Citation Score: 701.6162
- Similarity Product: 626.1375794958234

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test