PATENT CLAIM ANALYSIS

Application Number: 15753508
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "043000"]

Abstract:
Methods of treatment and dosage regimes using a composition comprising a tetracycline antibiotic in treating or alleviating a disorder including EGFRI associated rash, EGFRI associated rash related symptoms, a tetracycline antibiotic responsive EGFRI associated rash related disorder, skin disorder caused by a bacteria, and a tetracycline antibiotic responsive sebaceous gland disease, P. EGFRI associated rash bacteria associated disorders and other superficial infections, including skin infections are provided.

Claim (Index 80):
A method for treating acne vulgaris in a subject in need thereof, comprising administering to the subject a topical composition comprising an effective amount of a minocycline antibiotic in a carrier according to a dosing schedule such that\n (a) the mean maximum plasma concentration of the tetracycline antibiotic is about 0.2 ng/mL to about 5 ng/mL after at least one day of use, and/or (b) the mean maximum plasma concentration of the tetracycline antibiotic is about 0.2 ng/mL to about 12 ng/mL after at least 16 days of use, and/or (c) the area under the plasma concentration versus time curve at the last time point with a detectable drug concentration equal to or greater than the limit of quantification (AUCT) is about 36 ng*h/mL to 132 ng*h/mL, wherein the carrier is essentially waterless and comprises at least one hydrophobic solvent, at least one wax, at least one fatty alcohol, and at least one fatty acid, and wherein the carrier is combined with propellant to produce a foam.

Metadata:
- Claim Count in Document: 227.0
- Percentile: 88.0
- Lexical Diversity: 1.85
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15699692', '12795164', '13732024', '13831396', '15591733']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7919834525045732
- 35 USC 102 Novelty (BERT): 0.5283338554325809
- Combined Prediction Score: 0.765618492797374
- Mean Citation Score: 290.042484
- Max Citation Score: 353.14264
- Similarity Product: 240.1410180737209

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test