PATENT CLAIM ANALYSIS

Application Number: 15762523
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["544", "366000"]

Abstract:
The present invention provides an industrial method production of amorphous posaconazole. The present invention also relates to a method for production of the posaconazole via and novel crystalline forms of posaconazole intermediate. More particularly the present invention relates to novel crystalline forms of posaconazole intermediate and methods for production of novel crystalline forms of posaconazole intermediate represented by the following structural formula III Which is key intermediate in the production of posaconazole. The present invention also provides for the one pot process for the preparation of amorphous posaconazole using novel crystalline forms of benzyl posaconazole.

Claim (Index 14):
A crystalline B-2 form of 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one (III) as claimed in  claim 13  characterized by a XRD pattern as depicted in  FIG. 2 .

Metadata:
- Claim Count in Document: 7.0
- Percentile: 90.0
- Lexical Diversity: 2.30233
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15577818', '12970297', '12890812', '13477587', '14297142']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7885378114692161
- 35 USC 102 Novelty (BERT): 0.5424541794316119
- Combined Prediction Score: 0.7639294482654557
- Mean Citation Score: 356.18134
- Max Citation Score: 382.69504
- Similarity Product: 322.32909053932184

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test