PATENT CLAIM ANALYSIS

Application Number: 16008566
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "174000"]

Abstract:
5-hydroxytryptophan (5-HTP), a precursor of serotonin, is produced in a microbial host cell. A modified bacterial phenylalanine 4-hydroxylase (P4H) catalyzes the tryptophan 5-hydroxylation reaction. Optionally the host cell includes a cofactor regeneration mechanism, allowing continuous production of 5-HTP without supplementation of exogenous cofactors.

Claim (Index 8):
The genetically engineered bacterial cell of  claim 6  wherein the modified bacterial P4H further comprises at least one further mutation, said further mutation at any one, any two, or all three of amino acid positions 85, 223 and 282 of  X. campestris  P4H, or at any one, any two, or all three corresponding amino acid positions in a bacterial P4H enzyme from another species

Metadata:
- Claim Count in Document: 62.0
- Percentile: 94.0
- Lexical Diversity: 1.35897
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14809712', '14042270', '15370755', '10138970', '14326962']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.553041205940581
- 35 USC 102 Novelty (BERT): 0.5139020434851029
- Combined Prediction Score: 0.5491272896950332
- Mean Citation Score: 210.24073600000003
- Max Citation Score: 265.39935
- Similarity Product: 181.4075563198685

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test