PATENT CLAIM ANALYSIS

Application Number: 16084998
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["530", "356000"]

Abstract:
The present disclosure provides methods for capturing recombinant collagen 7 from cell culture and methods of purifying recombinant collagen 7. Also provided are compositions comprising purified recombinant collagen 7 that may be used for administration to humans.

Claim (Index 22):
The method of  claim 21 , further comprising before step a), the steps of:\n a) subjecting a supernatant harvested from a cell culture to a depth filter, wherein the supernatant contains recombinant human collagen 7; b) collecting a solution that flows through the depth filter; c) subjecting the solution from step b) to an ultrafiltration step, wherein the recombinant human collagen 7 concentrates in a layer adjacent to the ultrafiltration membrane; d) discarding a first retentate, wherein the first retentate comprises impurities contained in the solution from step (b); e) subjecting the layer adjacent to the ultrafiltration membrane to a solubilization agent and/or a surfactant to recover recombinant human collagen 7 and to obtain a second retentate comprising recombinant human collagen 7; f) subjecting the second retentate to a diafiltration step to obtain an unpurified bulk liquid comprising recombinant human collagen 7; and g) optionally freezing the unpurified bulk liquid.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 97.0
- Lexical Diversity: 1.3
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10532998', '11255800', '13262622', '11575833', '16065512']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6624181601300894
- 35 USC 102 Novelty (BERT): 0.4999356003766607
- Combined Prediction Score: 0.6461699041547465
- Mean Citation Score: 220.145652
- Max Citation Score: 230.56027000000003
- Similarity Product: 149.09321782912613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test