PATENT CLAIM ANALYSIS

Application Number: 16242386
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["540", "456000"]

Abstract:
The present invention relates to an FK506 derivative which has reduced immunosuppressive activity but maintains nerve regeneration activity, a preparing method thereof, and a pharmaceutical composition comprising the same for preventing or treating nervous system diseases. A composition comprising 9-deoxo-prolyl-FK506, 31-O-demethyl-FK506, or 9-deoxo-31-O-demethyl-FK506 can promote nerve regeneration and has reduced immunosuppressive activity, thereby reducing side effects in the treatment of nervous system diseases.

Claim (Index 1):
A method for treating a nervous system disease caused by neuronal damage,\n comprising administering a pharmaceutical composition with reduced immunosuppressive activity to a subject having the nervous system disease, comprising one or more FK506 derivatives selected from the group consisting of 31-O-demethyl-FK506 and 9-deoxo-31-O-demethyl-FK506.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 99.0
- Lexical Diversity: 1.42857
- Patent Class: 540.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15500353', '13774899', '13046304', '14635979', '11778319']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6437971973842203
- 35 USC 102 Novelty (BERT): 0.5696878078096871
- Combined Prediction Score: 0.6363862584267669
- Mean Citation Score: 260.62876800000004
- Max Citation Score: 486.67035
- Similarity Product: 331.94882333039044

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test