PATENT CLAIM ANALYSIS

Application Number: 15860738
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-07
Patent Classification: ["530", "333000"]

Abstract:
Disclosed herein is a process of preparing a polypeptide copolymer by polymerizing a mixture comprising N-carboxyanhydrides of alanine, tyrosine, carboxylate-protected glutamate and an amine-protected lysine, to form a protected polypeptide copolymer, which is contacted with a bromine scavenger to form a mixture; subsequently contacting the mixture with a solution of hydrogen bromide in acetic acid, to deprotect carboxylate-protected glutamate; followed by deprotection of the amine-protected lysine. Further disclosed herein is process of deprotecting carboxylate-protected glutamate in a protected polypeptide copolymer described herein by contacting the protected polypeptide copolymer with a bromine scavenger, and subsequently with hydrogen bromide in acetic acid. Further disclosed herein are polypeptide copolymers preparable according to a process as described herein, pharmaceutical compositions comprising same, and methods utilizing same for treating a medical condition.

Claim (Index 7):
The process of  claim 1 , wherein a molar ratio of said bromine scavenger to tyrosine residues in said protected polypeptide copolymer is at least 1.5:1.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 2.22222
- Patent Class: 530.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11223072', '11904422', '12726571', '12536023', '13985416']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.725722040869581
- 35 USC 102 Novelty (BERT): 0.5329415571651324
- Combined Prediction Score: 0.7064439924991361
- Mean Citation Score: 332.338296
- Max Citation Score: 366.69543
- Similarity Product: 277.3621026643341

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test