PATENT CLAIM ANALYSIS

Application Number: 15760878
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["424", "186100"]

Abstract:
Provided are polypeptides derived from the coronaviruses (CoVs) Spike protein (S) characterized by high affinity and specificity the S receptor and its neutralizing antibodies. Further provided are compositions and vaccines, and vaccine-based therapies targeting CoVs, and SARS and MERS viruses in particular.

Claim (Index 56):
A method for preventing, inhibiting, reducing, eliminating, protecting or delaying the onset of an infection or an infectious clinical condition caused by coronavirus, or of inducing an immune response against a coronavirus, in a subject in need thereof, the method comprising the step of administrating to said subject an effective amount of at least one polypeptide comprising an amino acid sequence of at least one reconstituted RBM of CoV Spike protein or of any fragment thereof, any derivative, enantiomer, fusion protein, conjugate or polyvalent dendrimer thereof or of any composition or vaccine comprising the same, wherein said reconstituted RBM comprises at least one linker and at least one fragment of the native RBM, said native RBM is a 30 to 200 amino acid sequence comprised within the RBD of said Spike protein forming a binding interface that interacts with the viral receptor.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.35135
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15306617', '10997201', '14375083', '15553466', '14717760']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7882618022542005
- 35 USC 102 Novelty (BERT): 0.5633406127988699
- Combined Prediction Score: 0.7657696833086676
- Mean Citation Score: 451.928406
- Max Citation Score: 490.51212
- Similarity Product: 346.87142593721865

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test