PATENT CLAIM ANALYSIS

Application Number: 16148055
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["424", "258100"]

Abstract:
A live bacterium, having a DNA construct stabilized against transduction of other bacteria, having a promoter sequence and encoding a fusion peptide, comprising a bacterial secretion peptide portion and a non-bacterial immunogenic polypeptide portion, having a nucleotide sequence coding for the non-bacterial immunogenic polypeptide portion which has at least one codon optimized for bacterial expression. The bacterium has a secretion mechanism which interacts with at least the bacterial secretion peptide portion to cause a secretion of the fusion peptide from the bacterium, and a genetic virulence attenuating mutation. The bacterium is adapted to act as an animal vaccine, to transiently infect a tissue of the animal, and cause an immunity response to the non-bacterial immunogenic polypeptide portion in the animal to a non-bacterial organism associated with the non-bacterial immunogenic polypeptide portion.

Claim (Index 10):
The live genetically engineered bacterium according to  claim 9 , wherein the live genetically engineered bacterium is  S. enterica  serovar  Typhimurium  ( S. typhimurium ), genetically engineered to delete IS200 elements, and to constitutively express P22 phage C2 repressor.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 97.0
- Lexical Diversity: 2.13636
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15131083', '13369333', '13892380', '15243904', '12560947']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.881061723976733
- 35 USC 102 Novelty (BERT): 0.6613329659017332
- Combined Prediction Score: 0.859088848169233
- Mean Citation Score: 662.1604659999998
- Max Citation Score: 778.4626
- Similarity Product: 615.5846801328063

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test