PATENT CLAIM ANALYSIS

Application Number: 16154501
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-09
Patent Classification: ["514", "291000"]

Abstract:
The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R 1 , R 2 , R 3 , R 5 , R 6 , R 8 , M 1 , M 2 , M 3 , M 4 , M 5 , M 6  and M 7  are each independently a member selected from the group consisting of H, C 1-6  alkyl, OH and C 1-6  hydroxyalkyl; R 4 , R 7  and R 9  are each independently selected from the group consisting of C 1-6  alkoxy and OH; R 10  is a member selected from the group consisting of H, —OH, —OP(O)Me 2 , —O—(CH 2 ) n —OH and —O—(CH 2 ) m —O—(CH 2 ) o —CH 3 , wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L 1  and L 4  are independently selected from the group consisting of: wherein each M 8  is independently a member selected from the group consisting of C 1-6  alkyl, OH and C 1-6  hydroxyalkyl; each of L 2  and L 3  are independently selected from the group consisting of: and salts, hydrates, isomers, metabolites, N-oxides and prodrugs thereof.

Claim (Index 1):
A method for the treatment or prevention of acute or chronic transplant rejection, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of the formula: or a salt, isomer, or N-oxide thereof, thereby treating or preventing the transplant rej ection.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 3.33333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15181284', '13302588', '12046024', '13333573', '13333526']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7528225233584128
- 35 USC 102 Novelty (BERT): 0.5903510854574743
- Combined Prediction Score: 0.736575379568319
- Mean Citation Score: 369.082184
- Max Citation Score: 476.28992
- Similarity Product: 467.4950078449632

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test