PATENT CLAIM ANALYSIS

Application Number: 15766088
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "001100"]

Abstract:
Lipoplex formulations and uses thereof. In particular, the lipoplexes include at least one naturally-occurring cationic amphiphile, at least one C18-30 saturated fatty acid, cholesterol, at least one nucleic acid, and have a low charge ratio. The lipoplexes are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic therapeutic or an antisense therapeutic, such as an RNAi agent) and allow prolonged expression of these agents, which may be distributed via endogenous cellular pathways to surrounding cells or tissue.

Claim (Index 3):
The lipoplex formulation of  claim 2 , wherein at least a portion of the cholesterol is conjugated to a ligand.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 1.42647
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12343342', '14255637', '15407512', '12903558', '14388192']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.760360635309671
- 35 USC 102 Novelty (BERT): 0.5279483240286394
- Combined Prediction Score: 0.737119404181568
- Mean Citation Score: 292.798712
- Max Citation Score: 311.9379
- Similarity Product: 213.0504150818109

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test