PATENT CLAIM ANALYSIS

Application Number: 15760660
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["424", "130100"]

Abstract:
Methods of diagnosis and methods of treatment and prevention for autism spectrum disorder are provided using decoy antigens to maternal brain-reactive antibodies.

Claim (Index 2):
A method of inhibiting or reducing development of an autism spectrum disorder in a fetus or an infant comprising extracorporeally contacting blood of a mother (i) pregnant with the fetus or (ii) prior to the fetus being born as an infant while the mother is pregnant, with an amount of an agent which binds an antibody directed to Caspr2, KCNAB2, KCNAB1, endothelial integrin ligand (EDIL3), IVD, brain specific sultatransferase (SULT4A1), TNIP2, retinoic acid induced 16 (RAI16) or GDP D5 so as to reduce the blood levels of an antibody directed to Caspr2, KCNAB2, KCNAB1, EDIL3, IVD, SULT4A1, TNIP2, RAI16 or GDP D5, and recirculating the blood so treated back into the mother effective to inhibit or reduce development of an autism spectrum disorder in a fetus or an infant.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 90.0
- Lexical Diversity: 1.09524
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15042976', '12266814', '11381943', '15353037', '15136021']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7071744505161679
- 35 USC 102 Novelty (BERT): 0.4819152714985577
- Combined Prediction Score: 0.6846485326144068
- Mean Citation Score: 172.780086
- Max Citation Score: 210.8995
- Similarity Product: 163.49930056053395

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test