PATENT CLAIM ANALYSIS

Application Number: 15922980
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "262100"]

Abstract:
To provide a novel compound having a HER2 inhibitory effect and having a cytostatic effect. It is also intended to provide a medicament useful in the prevention and/or treatment of a disease involving HER2, particularly, cancer, on the basis of the HER2 inhibitory effect. The present invention provides a compound of formula (I) wherein X, Y, Z 1 , Z 2 , Z 3 , Z 4 , W, n, R 1 , R 2 , and R 3  have meanings as defined in the present specification, or a salt thereof.

Claim (Index 17):
A method for inhibiting HER2, comprising administering an effective amount of a compound of formula (I) or a salt thereof to a subject in need thereof: wherein X represents an optionally substituted 4- to 10-membered nitrogen-containing saturated heterocyclic group; Y represents \u2014C(R 4 )\u2550C(R 5 )(R 6 ); Z 1 , Z 2 , Z 3 , and Z 4  are the same as or different from each other and each represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, an optionally substituted C1-C6 alkoxy group, an optionally substituted C1-C6 alkyl group, an optionally substituted amino group, an optionally substituted C3-C7 cycloalkyl group, a C6-C14 aromatic hydrocarbon group or a 4- to 14-membered unsaturated heterocyclic group, or Z 1  and Z 2 , or Z 3  and Z 4  optionally form, together with the respective carbon atoms bonded thereto, a benzene ring or a 5- to 7-membered saturated or unsaturated heterocyclic ring; W represents \u2014CH 2 \u2014, an oxygen atom, or \u2014NH\u2014; n represents an integer of from 0 to 2; R 1  represents an optionally substituted amino group; R 2  and R 3  are the same as or different from each other and each represent a hydrogen atom, an optionally substituted C1-C6 alkoxy group, an optionally substituted C1-C6 alkyl group, or an optionally substituted C6-C14 aromatic hydrocarbon group, or R 2  and R 3  optionally form, together with the nitrogen atom bonded thereto, an optionally substituted 4- to 8-membered nitrogen-containing saturated heterocyclic group; and R 4 , R 5 , and R 6  are the same as or different from each other and each represent a hydrogen atom or an optionally substituted C1-C6 alkyl group.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.76271
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15297196', '14784239', '14710631', '15861947', '12738885']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7646170223396694
- 35 USC 102 Novelty (BERT): 0.5428669027446159
- Combined Prediction Score: 0.7424420103801641
- Mean Citation Score: 354.839194
- Max Citation Score: 379.9677
- Similarity Product: 292.5433241856336

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test