PATENT CLAIM ANALYSIS

Application Number: 15914045
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "038000"]

Abstract:
A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R 1  is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Claim (Index 1):
A method for treating a genetic disorder associated with a premature stop codon mutation and/or a protein truncation phenotype, the method comprising administering to\n a subject in need thereof a therapeutically effective amount of the compound: or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 90.0
- Lexical Diversity: 1.37037
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15453990', '14461477', '13885715', '14866960', '14738892']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8857576856330918
- 35 USC 102 Novelty (BERT): 0.6882167514782905
- Combined Prediction Score: 0.8660035922176117
- Mean Citation Score: 738.9908280000003
- Max Citation Score: 847.47687
- Similarity Product: 681.4570914465701

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test