PATENT CLAIM ANALYSIS

Application Number: 15981808
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "006100"]

Abstract:
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.

Claim (Index 181):
The eukaryotic cell of  claim 180 , wherein one or more of the nucleic acids of a) and b) are one or more vectors, wherein the one or more vectors are selected from the group consisting of plasmids, cosmids, minicircles, phage, viral, retroviral, lentiviral, adenoviral, adeno-associated, and herpes simplex virus vectors; wherein the nucleotide sequence encoding said Cas9 protein and/or the one or more nucleotide sequence encoding said DNA-targeting RNA are operably linked to control elements operable in said eukaryotic cell.

Metadata:
- Claim Count in Document: 119.0
- Percentile: 93.0
- Lexical Diversity: 2.25424
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13842859', '15138604', '15803424', '14942782', '14685504']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5918709994414644
- 35 USC 102 Novelty (BERT): 0.7138331983767062
- Combined Prediction Score: 0.6040672193349886
- Mean Citation Score: 783.056874
- Max Citation Score: 815.14417
- Similarity Product: 624.7409054064959

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test