PATENT CLAIM ANALYSIS

Application Number: 16007685
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "025000"]

Abstract:
The present invention relates to beta-glycolipid derivatives, their preparation and use as adjuvants in vaccines, as being suitable for being co-administered with antigens for vaccine prophylaxis and therapy. In certain embodiments, the beta-glycolipid derivatives of the invention also in their salified or complex form, are suitable for being co-administered with antigens for both therapeutic and prophylactic purposes or for vaccine prophylaxis and therapy.

Claim (Index 1):
A method for enhancing and/or modulating the immune response following the administration of an antigen or a vaccine to a subject in need thereof, said method comprising the administration of a vaccine adjuvant composition, said vaccine adjuvant composition comprising at least one beta-glycolipid derivative of formula (I): a salt or a metal complex thereof, wherein the acetalic bond of the anomeric carbon has \u00df (beta) configuration, A 1  and A 2  are, independently of each other, saturated or monounsaturated linear or branched C 1 -C 30  alkyl, or are an acyl \u2014(CO)R 1  and \u2014(CO)R 2  respectively where R 1  and R 2  are, independently of each other, saturated or monounsaturated linear or branched C 1 -C 29  alkyl, and X is a sulphonic (\u2014SO 3 H), sulphuric (\u2014OSO 3 H), phosphoric (\u2014OPO 3 H 2 ), or phosphonic (\u2014PO 3 H 2 ) group, wherein said at least one beta-glycolipid derivative of formula (I) stimulates the immune system by activating antigen-presenting cells.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 94.0
- Lexical Diversity: 1.68293
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15325640', '12440315', '12684685', '15866378', '14847835']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6128048284622647
- 35 USC 102 Novelty (BERT): 0.5023264592016505
- Combined Prediction Score: 0.6017569915362033
- Mean Citation Score: 204.801332
- Max Citation Score: 242.09113
- Similarity Product: 169.73378327495217

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test