PATENT CLAIM ANALYSIS

Application Number: 16277785
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["514", "362000"]

Abstract:
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits a different biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.

Claim (Index 6):
The compound of  claim 1 , wherein the beta blocker residue is a residue of a beta blocker having the formula: wherein:\n R 2  is selected from the group consisting of branched C 3-4  alkyl, C 3-4  cycloalkyl, branched cyano(C 3-4  alkyl), phenyl (C 2-3  alkyl), halophenyl(C 2-3  alkyl), (C 1-4  alkoxy)phenyl(C 2-4  alkyl) and (C 1-4  acyl)amino(C 1-4  alkyl); \n alk is C 1-4  alkyl substituted by a 3 to 6 membered cycloalkyl group; \n Y is selected from the group consisting of \u2014O\u2014, \u2014S\u2014, and \u2014SO 2 \u2014; and \n R 15  is alkylene or alkyleneoxy.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 99.0
- Lexical Diversity: 1.55
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12530412', '15690106', '12674139', '14266317', '13319924']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8144107229812855
- 35 USC 102 Novelty (BERT): 0.5273815719853344
- Combined Prediction Score: 0.7857078078816904
- Mean Citation Score: 298.73018799999994
- Max Citation Score: 345.89764
- Similarity Product: 231.6585445104361

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test