PATENT CLAIM ANALYSIS

Application Number: 15905448
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["435", "007920"]

Abstract:
This document provides methods and materials related to high-throughput early detection of or point-of-care early detection of pregnant women susceptible to developing preeclampsia. For example, methods and materials related to performing flow cytometry or an ELISA to detect an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as being susceptible to developing preeclampsia later during her pregnancy are provided. In addition, methods and materials related to performing flow cytometry or an ELISA to detect a lack of an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as not being susceptible to developing preeclampsia later during her pregnancy are provided.

Claim (Index 21):
A method for timely avoiding maternal and fetal morbidity and death in a pregnant woman, wherein said method comprises treating said pregnant woman for hypertension, wherein\n a urine sample was obtained from said pregnant woman from gestational week 23 to gestational week 28 when said pregnant woman did not have preeclampsia, wherein said urine sample contained podocytes, wherein said urine sample was contacted with an antibody that binds to a podocyte or a polypeptide expressed by a podocyte to form a resulting sample, wherein said resulting sample contained antibody-podocyte complexes, wherein the presence of an elevated level of antibody-podocyte complexes within said resulting sample as compared to a control level of antibody-podocyte complexes present in urine samples obtained from between gestational weeks 30 and 36 of a random population of pregnant women who lacked preeclampsia throughout their pregnancies was detected via flow cytometry, and wherein later during the pregnancy of said pregnant women after said urine sample was obtained the presence of blood pressure greater than or equal to 140/90 mm Hg was detected in said pregnant woman or the presence of proteinuria greater than or equal to 300 mg of protein in a 24-hour urine sample from said pregnant woman was detected.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 2.5098
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14733521', '15408084', '12781474', '13053045', '11314073']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6873404467715964
- 35 USC 102 Novelty (BERT): 0.5696955837957827
- Combined Prediction Score: 0.6755759604740151
- Mean Citation Score: 414.391268
- Max Citation Score: 486.53308
- Similarity Product: 382.95147155727625

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test