PATENT CLAIM ANALYSIS

Application Number: 16073620
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "210180"]

Abstract:
A compound represented by general formula (I-1): wherein the symbols are defined in the specification, has a selective S1P 5  receptor binding activity and modulates the function of an S1P5 receptor, and can therefore be a therapeutic agent for a S1P 5 -mediated disease, for example, neurodegenerative diseases such as schizophrenia, Binswanger's disease and the like.

Claim (Index 1):
A compound represented by general formula (I-1): wherein, X 1  and X 2  each represent independently a CH 2  or an NH, provided that X 1  and X 2  are not represent NH at the same time, Y represents (1) \u2014CH 2 \u2014, (2) \u2014NH\u2014, (3) \u2014S\u2014 or (4) \u2014O\u2014, W A  represents (1) a C1-12 alkylene group, (2) a C2-12 alkenylene group, (3) a C2-12 alkynylene group, (4) \u2014C1-12 alkylene-O\u2014, (5) \u2014C2-12 alkenylene-O\u2014, (6) \u2014C2-12 alkynylene-O\u2014, (7) \u2014C1-12 alkylene-ring2-, (8) \u2014C2-12 alkenylene-ring2- or (9) \u2014C2-12 alkynylene-ring2-, wherein, an alkylene group, an alkenylene group and an alkynylene group may be substituted with one to five halogen atoms, R 1  represents (1) -L-, (2) -L-ring3- or (3) -L-NR 13 \u2014, R 2  represents (1) a halogen atom, (2) a C1-4 alkyl group, (3) a C1-4 haloalkyl group, (4) a C1-4 alkoxy group or (5) a C1-4 haloalkoxy group, R 3-1  represents (1) a halogen atom, (2) a C1-4 alkyl group, (3) a C1-4 haloalkyl group, (4) a C1-4 alkoxy group, (5) a C1-4 haloalkoxy group, (6) a nitrile group, (7) \u2014S\u2014C1-4 alkyl group, (8) \u2014S\u2014C1-4 haloalkyl group or (9) an oxo group, provided that the C1-4 alkyl group or the C1-4 haloalkyl group represented by R 3-1  is branched chain, C1-2 alkyl groups branched from the same carbon atom may be taken together with a carbon atom to which they are bound, to form a C3-4 saturated carbocyclic ring, R 13  represents (1) a hydrogen atom or (2) a C1-4 alkyl group, L represents (1) a bond or (2) a group represented by general formula wherein, R 11  and R 12  each represent independently a hydrogen atom or a C1-4 alkyl group, or R 11  and R 12  may be taken together with a carbon atom to which they are bound, to form a C3-7 carbocyclic ring, and t represents an integer of 1 to 6, Z represents (1) a carboxyl group which may be substituted with a C1-8 alkyl group, (2) a hydroxy group which may be substituted with a C1-8 alkyl group, (3) a hydroxamic acid group which may be substituted with a C1-8 alkyl group, (4) a sulfonic acid group which may be substituted with a C1-8 alkyl group, (5) a boronic acid group which may be substituted with a C1-8 alkyl group, (6) a carbamoyl group which may be substituted with a C1-8 alkyl group, (7) a sulfamoyl group which may be substituted with a C1-8 alkyl group, (8) a sulfoximine group which may be substituted with a C1-8 alkyl group or (9) a tetrazolyl group, ring 1 represents (1) a C3-10 carbocyclic ring or (2) a 3- to 10-membered heterocyclic ring, ring 2 represents (1) a C3-7 carbocyclic ring or (2) a 3- to 7-membered heterocyclic ring, ring 3 represents (1) a C3-7 carbocyclic ring which may be substituted with a C1-4 alkyl group or (2) a 3- to 7-membered heterocyclic ring which may be substituted with a C1-4 alkyl group, m represents an integer of 0 to 2, n represents an integer of 0 to 2, p represents an integer of 0 to 3, q represents an integer of 0 to 5, v represents an integer of 0 to 1, when p is 2 or more, a plurality of R 2 s may be the same or different, when q is 2 or more, a plurality of R 3-1 s may be the same or different, when t is 2 or more, a plurality of R 11 s may be the same or different, and when t is 2 or more, a plurality of R 12 s may be the same or different, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 95.0
- Lexical Diversity: 1.32
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14001936', '15034905', '10530249', '15539530', '10488835']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7750249370342868
- 35 USC 102 Novelty (BERT): 0.530895932489601
- Combined Prediction Score: 0.7506120365798182
- Mean Citation Score: 315.965848
- Max Citation Score: 323.4134200000001
- Similarity Product: 217.67249190416103

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test