PATENT CLAIM ANALYSIS

Application Number: 16269477
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-05
Patent Classification: ["800", "006000"]

Abstract:
Genetically modified mice are provided that express human λ variable (hVλ) sequences, including mice that express hVλ sequences from an endogenous mouse λ light chain locus, mice that express hVλ sequences from an endogenous mouse κ light chain locus, and mice that express hVλ, sequences from a transgene or an episome wherein the hVλ sequence is linked to a mouse constant sequence. Mice are provided that are a source of somatically mutated human λ variable sequences useful for making antigen-binding proteins. Compositions and methods for making antigen-binding proteins that comprise human λ variable sequences, including human antibodies, are provided.

Claim (Index 40):
The genetically modified mouse of  claim 21 , wherein the one or more unrearranged human J\u03bb gene segments of (b) and the one or more human C\u03bb gene segments of (c) are present as J-C clusters.

Metadata:
- Claim Count in Document: 101.0
- Percentile: 99.0
- Lexical Diversity: 2.15686
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14636784', '14638429', '14943890', '13166171', '13945573']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9016919569809444
- 35 USC 102 Novelty (BERT): 0.7596009135240847
- Combined Prediction Score: 0.8874828526352584
- Mean Citation Score: 1056.75256
- Max Citation Score: 1073.7893
- Similarity Product: 850.9622960347771

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test