PATENT CLAIM ANALYSIS

Application Number: 15766560
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["544", "001000"]

Abstract:
The present invention provides a compound of the formula (1): wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , Y 1 , Y 2 , L, and m are as defined in the description, and a pharmaceutically acceptable salt thereof, which are useful as a vaccine adjuvant.

Claim (Index 1):
A compound of the formula (1) or a pharmaceutically acceptable salt thereof: wherein\n X is methylene, oxygen atom, sulfur atom, SO, SO 2  or NR 7  wherein R 7  is hydrogen atom or an alkyl group of 1 to 3 carbon atoms; \n R 1  and R 2  are independently hydrogen atom or a substituted or unsubstituted alkyl group of 1 to 6 carbon atoms, provided that when the alkyl group is substituted, it is substituted with 1 to 4 substituents independently selected from the group consisting of hydroxy group, halogen atom, and an alkoxy group of 1 to 6 carbon atoms; \n R 3  is an alkyl group of 1 to 6 carbon atoms, an alkoxy group of 1 to 6 carbon atoms, or an alkylthio group of 1 to 6 carbon atoms; \n R 4  is hydrogen atom, halogen atom, hydroxy group, an alkyl group of 1 to 6 carbon atoms, an alkoxy group of 1 to 6 carbon atoms, or cyano group; \n Y 1  is a single bond, \u2014(CR 9 R 10 ) p \u2014, \u2014CH\u2550CH\u2014(CR 9 R 10 ) q \u2014, \u2014C\u2261C\u2014(CR 9 R 10 ) q\u2032 \u2014 or \u2014(CR 9 R 10 ) r \u2014O\u2014(CR 9\u2032 R 10\u2032 ) r\u2032 \u2014 wherein R 9 , R 10 , R 9\u2032 , and R 10\u2032  are independently hydrogen atom or an alkyl group of 1 to 4 carbon atoms; \n Y 2  is a single bond or \u2014C(O)\u2014; \n L is a substituted or unsubstituted straight chain alkylene of 2 to 6 carbon atoms or a divalent group derived from 4- to 8-membered cycloalkane, provided that when the straight chain alkylene or the cycloalkane is substituted, it is substituted with 1 to 4 same or different substituents independently selected from the group consisting of alkyl group of 1 to 5 carbon atoms, hydroxy group and halogen atom, and wherein any one of the methylene groups in the straight chain alkylene of L is optionally replaced with carbonyl group; \n R 5  and R 6  are independently hydrogen atom or a substituted or unsubstituted alkyl group of 1 to 6 carbon atoms, provided that when the alkyl group is substituted, it is substituted with 1 to 4 substituents independently selected from the group consisting of hydroxy and halogen; \n or R 5  and R 6  are taken together to form a substituted or unsubstituted 5- to 8-membered nitrogen-containing saturated heterocycle; provided that when the 5 to 8-membered nitrogen-containing saturated heterocycle is substituted, it is substituted with 1 to 4 substituents independently selected from the group consisting of methyl group, ethyl group, propyl group, hydroxymethyl group, hydroxyethyl group, carbonyl group, hydroxy group, and halogen atom; \n m is 0 or 1; \n p is an integer of 1 to 6; \n q and q\u2032 are each independently an integer of 0 to 4; \n r is an integer of 0 to 5, and \n r\u2032 is an integer of 1 to 5, provided that r\u2032 is an integer of 2 or more when the sum of r and r\u2032 is 5 or less and Y 2  is a single bond; and \n each   is independently a single bond or a double bond.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 91.0
- Lexical Diversity: 1.65
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15763982', '15356311', '13416061', '10110381', '15507888']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7848762333499019
- 35 USC 102 Novelty (BERT): 0.5501621170480133
- Combined Prediction Score: 0.761404821719713
- Mean Citation Score: 307.9729240000001
- Max Citation Score: 405.57785
- Similarity Product: 352.1938602421016

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test