PATENT CLAIM ANALYSIS

Application Number: 15764441
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["548", "465000"]

Abstract:
A lipid derivative in which a hydrophilic polymer is bound through a cyclic benzylidene acetal linker, and which can accurately control a hydrolysis rate in the weakly acidic environment of a living body to detach the hydrophilic polymer from a lipid membrane structure. The lipid derivative is represented by formula (1): wherein, R 1  and R 6  are each independently a hydrogen atom or a hydrocarbon group; R 2 , R 3 , R 4  and R 5  are each independently an electron-withdrawing or electron-donating substituent or a hydrogen atom; R 7  is a hydrocarbon group having from 8 to 24 carbon atoms, an acyl group having from 8 to 24 carbon atoms, a cholesterol derivative, a glycerolipid, a phospholipid or a sphingolipid; P is a hydrophilic polymer; s is 1 or 2, t is 0 or 1, and s+t is 1 or 2; and Z 1  and Z 2  are each independently a selected divalent spacer.

Claim (Index 19):
The lipid derivative as claimed in  claim 2 , wherein P is a linear or branched polyethylene glycol having a hydrocarbon group or a chemically reactive functional group at a terminal thereof.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 90.0
- Lexical Diversity: 2.10843
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15512727', '13632353', '12830746', '11142683', '13435556']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7418377067801235
- 35 USC 102 Novelty (BERT): 0.5418576766944136
- Combined Prediction Score: 0.7218397037715526
- Mean Citation Score: 241.081628
- Max Citation Score: 392.15363
- Similarity Product: 296.22962725083414

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test