PATENT CLAIM ANALYSIS

Application Number: 16355773
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["514", "414000"]

Abstract:
The invention discloses 20,23-modified novel derivatives of 16-membered demycarosyltylonolide antibiotics, which are useful against bacterial and mycoplasmic pathogens in humans and animals. Also claimed are pharmaceutical compositions of such derivatives and their use in treating bacterial and mycoplasmic infections in humans and animals.

Claim (Index 7):
A compound or pharmaceutically acceptable salt thereof according to  claim 1  selected from the group consisting of:\n (4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-((benzyl(methyl)amino)methyl)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-7-(2-(isoindolin-2-yl)ethyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione; \n (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-7-(2-(isoindolin-2-yl)ethyl)-5,9,13-trimethyl-15-(piperidin-1-ylmethyl)oxacyclohexadeca-11,13-diene-2,10-dione; \n (4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-((diethylamino)methyl)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-7-(2-(isoindolin-2-yl)ethyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione; and \n (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-15-((3,5-dimethylpiperidin-1-yl)methyl)-16-ethyl-4-hydroxy-7-(2-(isoindolin-2-yl)ethyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 99.0
- Lexical Diversity: 1.4375
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14789996', '11214988', '13863781', '09485292', '09979939']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7868055155096634
- 35 USC 102 Novelty (BERT): 0.8379927234524479
- Combined Prediction Score: 0.7919242363039418
- Mean Citation Score: 559.4641740000002
- Max Citation Score: 1135.3839
- Similarity Product: 1110.1411698452714

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test