PATENT CLAIM ANALYSIS

Application Number: 16035362
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["424", "133100"]

Abstract:
Embodiments described herein relate to restorative solutions for segmental peripheral nerve (PN) defects using allografted PNs for stimulating PN repair. More specifically, embodiments described herein provide for localized immunosuppression (LIS) surrounding PN allografts as an alternative to systemically suppressing a patient's entire immune system. Methods include localized release of immunosuppressive (ISV) agents are contemplated in one embodiment. Methods also include localized application of immunosuppressive (ISV) regulatory T-cells (Tregs) in other embodiments. Hydrogel carrier materials for delivery of ISV agents and are also described herein.

Claim (Index 5):
The method of  claim 4 , wherein the one or both of T-regs and mesenchymal stomal cells are dispersed within the hydrogel material.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 1.55385
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15457359', '16035355', '11817923', '14352024', '10218316']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7266208378510929
- 35 USC 102 Novelty (BERT): 0.6400783632112249
- Combined Prediction Score: 0.7179665903871061
- Mean Citation Score: 376.914282
- Max Citation Score: 678.3068
- Similarity Product: 527.6958427827358

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test