PATENT CLAIM ANALYSIS

Application Number: 15999117
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["424", "001890"]

Abstract:
Provided herein are monoacylglycerol lipase (MGLL) occupancy probes comprising a MGLL inhibitor containing a positron emission tomography (PET) tracer radionuclide. Also provided are methods of assessing MGLL enzyme occupancy of a MGLL inhibitor using the radiolabeled occupancy probes described herein.

Claim (Index 30):
A compound having the structure of Formula (V): wherein p is 0, 1, or 2; R d  is H or C 1-6 alkyl; L 3  is a bond, \u2014CH 2 \u2014, \u2014S(O) 2 \u2014, or \u2014C(O)\u2014; R 7  is phenyl substituted by R a R b N\u2014 and a moiety selected from the group consisting of: halogen and C 1-6 alkyl (optionally substituted by one, two, or three halogens); R a  and R b , together with the nitrogen to which they are attached, form a 4-6 membered heterocyclic ring or a 9-10 membered bicyclic heterocycle or spirocyclic ring, which may have an additional heteroatom selected from O, S, and N; wherein the 4-6 membered heterocyclic ring or 9-10 membered bicyclic heterocycle or spirocycle is substituted by C 1-6 haloalkyl; or a solvate, hydrate, tautomer, stereoisomer, or pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 96.0
- Lexical Diversity: 1.48387
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13043956', '13479826', '14003547', '14764426', '13391402']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7713598048496373
- 35 USC 102 Novelty (BERT): 0.4977161444018458
- Combined Prediction Score: 0.7439954388048582
- Mean Citation Score: 262.048626
- Max Citation Score: 265.28232
- Similarity Product: 207.3508276100064

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test