PATENT CLAIM ANALYSIS

Application Number: 15942156
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-03
Patent Classification: ["424", "488000"]

Abstract:
Compositions and methods for the treatment of vasospasm are provided comprising applying an amount of a semi-solid vasoactive prostaglandin composition to the affected tissue. Also provided are methods of improving microcirculation in a replanted body part.

Claim (Index 79):
A method of treating vasospasm in an ear of a subject comprising applying directly to a surface of the ear of the subject needing improvement of vasospasm a composition comprising:\n one or more of prostaglandin El, a pharmaceutically acceptable salt of prostaglandin El, and a Ci to C4 alkyl ester of prostaglandin El or a pharmaceutically acceptable salt thereof, wherein the dose per application is about 0.08 mg to about 0.64 mg prostaglandin El; a penetration enhancer selected from the group consisting of an alkyl-(N-substituted amino) alkanoate, an alkyl-2-(N,N-disubstituted amino) alkanoate, an (N-substituted amino) alkanol alkanoate, an (N,N-disubstituted amino) alkanol alkanoate, a pharmaceutically acceptable salt thereof, and a mixture thereof; a shear-thinning polymer thickener selected from the group consisting of a shear-thinning polysaccharide gum and a shear-thinning polyacrylic acid polymer; a lipophilic component that is selected from the group consisting of an aliphatic Ci to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof; water and a buffer system that provides a buffered pH.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 90.0
- Lexical Diversity: 1.26667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11875725', '10806072', '14463921', '14463959', '14463966']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7598058818220852
- 35 USC 102 Novelty (BERT): 0.6024470322052599
- Combined Prediction Score: 0.7440699968604026
- Mean Citation Score: 400.618376
- Max Citation Score: 577.91016
- Similarity Product: 460.8149852994204

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test