PATENT CLAIM ANALYSIS

Application Number: 16186451
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["536", "124000"]

Abstract:
Disclosed herein are soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.

Claim (Index 17):
A sterile, stable injectable soft tissue filler composition comprising:\n a mixture of soluble form hyaluronic acid (HA), crosslinked HA, and lidocaine in an amount effective to mitigate pain upon injection of the composition, the crosslinked HA being crosslinked with 1,4-butanediol diglycidyl ether (BDDE); the composition having a HA concentration of between about 20 mg/ml and about 30 mg/ml; wherein the sterile, stable injectable soft tissue filler composition is made by a process comprising:\n providing the soluble form HA and crosslinked HA; \n adjusting the pH of the soluble form HA and crosslinked HA; \n adding a solution containing lidocaine to the soluble form HA and crosslinked HA having the adjusted pH to obtain a HA-based injectable soft tissue filler composition; and \n heat sterilizing the HA-based injectable soft tissue filler composition to obtain the sterile, stable injectable soft tissue filler composition.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 98.0
- Lexical Diversity: 1.57143
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12393884', '12393768', '13891052', '16186448', '15173850']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6872733228620111
- 35 USC 102 Novelty (BERT): 0.5812330794475459
- Combined Prediction Score: 0.6766692985205647
- Mean Citation Score: 485.48709
- Max Citation Score: 515.6925
- Similarity Product: 435.4149010263383

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test