PATENT CLAIM ANALYSIS

Application Number: 15976847
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["424", "490000"]

Abstract:
An improved microparticle or lyophilized or otherwise reconstitutable microparticle composition thereof for medical therapy, including ocular therapy.

Claim (Index 30):
A solid aggregating microparticle comprising a pharmaceutically active agent of a therapeutically active compound, encapsulated in at least one biodegradable polymer and at least one hydrophobic polymer covalently bound to a hydrophillic polymer, wherein the microparticle has a mean diameter between 10 \u03bcm and 60 \u03bcm and surface surfactant and that:\n (i) has a solid core with less than 10% porosity by ratio of void space to total volume; (ii) has a modified surface which has been treated under mild conditions at a temperature less than about 18\u00b0 C. to remove surface surfactant; (iii) is capable of aggregating in vivo to form at least one pellet of at least 500 \u03bcm in vivo capable of sustained drug delivery in vivo for at least three months; (iv) wherein the active agent is selected from Tivosinib, Imatinib, Gefitinib, Erlotinib, Lapatinib, Canertinib, Semaxinib, Vatalaninib, Sorafenib, Axitinib, Pazopanib, Dasatinib, Nilotinib, Crizotinib, Ruxolitinib, Vandetanib, Vemurafenib, Bosutinib, Cabozantinib, Regorafenib, Vismodegib, and Ponatinib.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 93.0
- Lexical Diversity: 1.1875
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15349985', '15782755', '15273686', '13995727', '15782744']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7339564763380423
- 35 USC 102 Novelty (BERT): 0.542173280252215
- Combined Prediction Score: 0.7147781567294595
- Mean Citation Score: 283.64715200000006
- Max Citation Score: 399.21332
- Similarity Product: 304.8419053243065

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test