PATENT CLAIM ANALYSIS

Application Number: 15756214
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["540", "222000"]

Abstract:
The present invention relates to a highly convergent method for the synthesis and purification of ceftolozane and intermediates starting from 7-aminocephaiosporanic acid (7-ACA).

Claim (Index 12):
A method for preparing a compound of formula I as defined in  claim 1  from a compound of formula V wherein R 1 , R 2 , R 3  and R 4  are independently an amino protecting group or hydrogen with the condition that R 4  is not hydrogen if R 3  is hydrogen, or R 1  and R 2 , and/or R 3  and R 4  are bound together by a cyclic amino protecting group, R 6\u2032  is hydrogen or a negative charge, and R 7  is hydrogen or an amino protecting group, R 10  is an ester protecting group, and A 2 \u25ef  is an anion, with the condition that n is zero when R 6\u2032  is a negative charge, and n is one when R 6\u2032  is hydrogen, or from a compound of formula VII wherein\n R 3\u2032 , R 4\u2032 , R 6\u2032 , R 7\u2032  and R 10\u2032  are defined as R 3 , R 4 , R 6\u2032 , R 7  and R 10  in  claim 1 , respectively with the exception that R 3\u2032 , R 4\u2032 , R 7\u2032  and R 10\u2032  are not triphenylmethyl and if R 3  and/or R 4  and/or R 7  and/or R 10  are triphenvlmethyl in the compound of formula V R 3\u2032  and/or R 4\u2032  and/or R 7\u2032  and/or R 10\u2032  are hydrogen in the compound of formula VII, respectively, and \n A 3 \u2296  is an anion, with the condition that n is zero when R 6\u2032  is a negative charge, and n is one when R 6\u2032  is hydrogen.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 88.0
- Lexical Diversity: 1.04
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15503564', '10695895', '10475845', '15319104', '14895809']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6562821845025892
- 35 USC 102 Novelty (BERT): 0.5153687820811007
- Combined Prediction Score: 0.6421908442604404
- Mean Citation Score: 233.91299
- Max Citation Score: 239.83994
- Similarity Product: 159.2858791411364

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test