PATENT CLAIM ANALYSIS

Application Number: 16336363
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["514", "234200"]

Abstract:
The present invention relates to a class of cyano-substituted-heterocycles of Formula (I) with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having utility in a variety of therapeutic areas including cancer and conditions involving mitochondrial dysfunction. (I)

Claim (Index 6):
A compound for use, according to  claim 5 , wherein\n ring A is selected from pyrrolidinyl, piperidinyl, azepanyl, diazepanyl, dihydrofuranyl, 2,3-dihydrofuranyl, 2,5-dihydrofuranyl, dioxolanyl, morpholinyl, oxazolidinyl, oxazinanyl, indolinyl, isoindolinyl, piperazinyl, tetrahydrofuranyl, thiomorpholinyl, dihydropyranyl, 3,4-dihydropyranyl, 3,6-dihydropyranyl, homopiperazinyl, dioxanyl, hexahydropyrimidinyl, pyrazolinyl, pyrazolidinyl, 4H-quinolizinyl, quinuclidinyl, tetrahydropyranyl, tetrahydropyridinyl, tetrahydropyrimidinyl, tetrahydrothiophenyl, thiazolidinyl, benzopyranyl, tetrahydroquinolinyl dihydropyrrolopyridinyl, dihydrobenzoxazinyl, pyrrolopyridinyl, dihydroisoquinolinyl, tetrahydroisoquinolinyl, pyridinyl, pyrazinyl, pyrimidinyl, pyridazinyl, furanyl, thiophenyl, pyrrolyl, oxazolyl, thiazolyl, pyrazolyl, triazolyl, tetrazolyl, indolyl, indolizinyl, isoindolyl, purinyl, furazanyl, imidazolyl, indazolyl, isothiazolyl, isoxazolyl, oxadiazolyl, tetrazolyl, thiadiazolyl, benzofuranyl, isobenzofuranyl, benzothiophenyl, isobenzothiophenyl, benzimidazolyl, benzothiazolyl, benzoxazolyl, napthyridinyl, pteridinyl, pyrazinyl, quinolinyl, isoquinolinyl, cinnolinyl, phthalazinyl, quinazolinyl, imidazopyridinyl, pyrazolopyridinyl, thiazolopyridinyl, triazinyl, dihydropyridinyl, dihydropyrrolopyridinyl, quinoxalinyl, dihydrobenzoxazinyl, oxazolopyridinyl, and tetrahydropyrazinyl; which is unsubstituted, or substituted with 1 to 4 Q 1 (R 1 ) n  groups, which may be the same or different.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 99.0
- Lexical Diversity: 1.32558
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16070936', '16080506', '15738900', '15894025', '16078518']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8441863450088172
- 35 USC 102 Novelty (BERT): 0.5588833700658735
- Combined Prediction Score: 0.8156560475145228
- Mean Citation Score: 433.761262
- Max Citation Score: 448.00748
- Similarity Product: 346.56375823477026

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test