PATENT CLAIM ANALYSIS

Application Number: 15896811
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "006100"]

Abstract:
Hence, the invention relates to a method for diagnosis and/or prognosis of cancer, comprising the steps of analyzing in a sample of a subject the DNA methylation status of a genomic region of at least one member of the group of, (i) SFN according to SEQ ID NO. 1, (ii) SLIT2 according to SEQ ID NO. 2, (iii) SERPINB5 according to SEQ ID NO. 3; and (iv) TWIST 1 according to SEQ ID NO 4; wherein, if (i) SFN shows a methylation cut-off value of above 80% and/or, (ii) SLIT2 shows a methylation cut-off value of above 45% and/or, (iii) SERPBINB5 shows a methylation cut-off value of above 70%, and/or (iv) TWIST 1 shows a methylation level below 15% the sample is categorized as a sample from a patient with cancer and/of a poor prognosis.

Claim (Index 31):
The kit of  claim 29 , in which the kit further comprises one or more nucleic acid molecules that hybridize under stringent conditions to at least one of the APC gene, HLAa gene, and the NKX2-5.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 2.32877
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14386292', '10517741', '10582705', '15079948', '12520841']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6528604167879908
- 35 USC 102 Novelty (BERT): 0.5530372502957724
- Combined Prediction Score: 0.642878100138769
- Mean Citation Score: 334.599082
- Max Citation Score: 449.0426
- Similarity Product: 312.9574380074501

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test