PATENT CLAIM ANALYSIS

Application Number: 15975423
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["424", "179100"]

Abstract:
The present disclosure relates to compounds of formula (I): RCG1-L-P  (I) wherein RCG1 represents a reactive chemical group being reactive towards a chemical group present on a polypeptide such as an antibody; P represents H, OH or an activated O; and L represents a specific linker. The disclosure also relates to cryptophycin payloads, as well as to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The disclosure also relates to the process for preparing these conjugates.

Claim (Index 8):
The compound of formula (I) according to  claim 1 , wherein A 7  represents a \u2014C(\u2550O)\u2014[(CH 2 ) 2 \u2014O] 4 \u2014CH 3  group,\n a \u2014C(\u2550O)\u2014[(CH 2 ) 2 \u2014O] 7 \u2014CH 3  group, a \u2014C(\u2550O)\u2014[(CH 2 ) 2 \u2014O] 24 \u2014CH 3  group; a \u2014C(\u2550O)\u2014(CH 2 ) 2 \u2014C(\u2550O)\u2014NH\u2014(CH 2 ) 2 \u2014SO 3 H group, a \u2014C(\u2550O)\u2014(CH 22 \u2014C(\u2550O)\u2014NH\u2014[(CH 2 ) 2 \u2014O\u2014] 4 \u2014(CH 2 ) 2 \u2014C(\u2550O)\u2014NH\u2014(CH 2 ) 2 \u2014SO 3 H group; and\n wherein \u2014CH(SO 3 H)\u2014 is optionally the alkali metal salt.

Metadata:
- Claim Count in Document: 55.0
- Percentile: 93.0
- Lexical Diversity: 1.61667
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14069057', '15581749', '15280563', '14843520', '14818455']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7688424712820757
- 35 USC 102 Novelty (BERT): 0.521892656977655
- Combined Prediction Score: 0.7441474898516337
- Mean Citation Score: 309.744996
- Max Citation Score: 313.26495
- Similarity Product: 203.0857808197707

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test