PATENT CLAIM ANALYSIS

Application Number: 15981574
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-07
Patent Classification: ["514", "299000"]

Abstract:
Efficient methods are provided for large scale production of ethyl cocaine-free cocaine hydrochloride. Compositions and methods comprising administration of cocaine hydrochloride are provided.

Claim (Index 18):
An aqueous topical pharmaceutical composition comprising\n 2 to 20 wt % (\u2212)-cocaine hydrochloride having not more than 0.05% ethyl cocaine, and having not more than 1.0% total impurities, and a pharmaceutically acceptable carrier, wherein the composition is capable of exhibiting in a healthy adult subject following topical administration of about 4 mL of the composition comprising a dose from about 160 mg to about 400 mg (\u2212)-cocaine hydrochloride to nasal mucosa of the subject for a period of about 20 minutes, a plasma (\u2212)-cocaine pharmacokinetic parameter selected from the group consisting of: a) Tmax of 25-35 min; b) systemic absorption between 20 to 35% of the administered dose; and c) apparent elimination half life of 1 to 3 hrs.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 93.0
- Lexical Diversity: 1.38889
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11303309', '15470133', '15245935', '15849575', '15935776']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6931524042313777
- 35 USC 102 Novelty (BERT): 0.5160982755997117
- Combined Prediction Score: 0.6754469913682111
- Mean Citation Score: 250.173112
- Max Citation Score: 308.0337
- Similarity Product: 234.51423454749585

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test