PATENT CLAIM ANALYSIS

Application Number: 16231581
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["607", "045000"]

Abstract:
A method of inhibiting the release of a proinflammatory cytokine in a cell is disclosed. The method comprises treating the cell with a cholinergic agonist. The method is useful in patients at risk for, or suffering from, a condition mediated by an inflammatory cytokine cascade, for example endotoxic shock. The cholinergic agonist treatment can be effected by stimulation of an efferent vagus nerve fiber, or the entire vagus nerve.

Claim (Index 9):
The method of  claim 1 , wherein the condition is selected from the group consisting of diseases involving the gastrointestinal tract and associated tissues; systemic or local inflammatory diseases and conditions; diseases involving the urogential system and associated tissues; diseases involving the respiratory system and associated tissues; diseases arising from infection by various viruses, bacteria, fungi and protozoal and multicellular parasites; dermatological diseases and conditions of the skin; diseases involving the cardiovascular system and associated tissues; diseases involving the central or peripheral nervous system and associated tissues; diseases of the bones, joints, muscles and connective tissues; other autoimmune and inflammatory disorders; and various cancers, tumors and proliferative disorders.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 98.0
- Lexical Diversity: 1.60417
- Patent Class: 607.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10990938', '15616855', '14569504', '10446625', '10729427']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8615574158246387
- 35 USC 102 Novelty (BERT): 0.6818514152964296
- Combined Prediction Score: 0.8435868157718178
- Mean Citation Score: 671.885124
- Max Citation Score: 735.4096
- Similarity Product: 526.3565624588966

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test