PATENT CLAIM ANALYSIS

Application Number: 15890028
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "006110"]

Abstract:
A sequencing method comprising: (i) combining a template nucleic acid having a first optical detection label at the end with a primer to obtain a first complex; (ii) imaging the first complex to obtain a first image; (iii) mixing the first complex, polymerase, and one or more of nucleotides with a optical detection label to obtain an extension product by polymerization reaction; (iv) imaging the extension product to obtain a second image; (v) removing the cleavable group of the nucleotides with the optical detection label from the extension product to obtain a second complex; (vi) repeating the above steps (ii) to (v) once or more times to determine the template nucleic acid sequence. The sequencing method can achieve single molecule sequencing by capturing template nucleic acids through primers.

Claim (Index 4):
A method according to  claim 3 , wherein the primer is attached to a substrate with surface-modified epoxy through an amino group modified at the 5 \u2032end.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 88.0
- Lexical Diversity: 2.16901
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12618991', '12114163', '12559902', '15654406', '12553478']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.643113307324495
- 35 USC 102 Novelty (BERT): 0.5005614918154596
- Combined Prediction Score: 0.6288581257735916
- Mean Citation Score: 252.653482
- Max Citation Score: 259.30356
- Similarity Product: 186.40880721920013

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test