PATENT CLAIM ANALYSIS

Application Number: 15991823
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["210", "656000"]

Abstract:
The invention relates to a method for setting a gradient delay volume GDV of a liquid chromatography system for a chromatography run in liquid chromatography, in particular a high-performance liquid chromatography system, in which a desired value GDV target  of a gradient delay volume of the liquid chromatography system is ascertained or predefined and, if the value GDV target  deviates from a specific fixed value GDV actual  of a liquid chromatography system, this value GDV target  is set in a range 0≤ΔGDV=GDV target −GDV actual ≤V max  of a volume of a volume adjustment device  5 . Furthermore, the invention relates to an automatic sampler for carrying out such a method.

Claim (Index 1):
A method for setting a gradient delay volume of a liquid chromatography system for a chromatography run, the method comprising:\n setting, and inputting into a control unit of the liquid chromatography system, a target gradient delay volume (GDV target ), wherein the target gradient delay volume (GDV target ) is predefined based on an earlier chromatography run of the liquid chromatography system; calculating, by the control unit, a difference of the gradient delay volume (\u0394GDV) between the target gradient delay volume (GDV target ) and an actual gradient delay volume (GDV atual ) of the liquid chromatography system for the chromatography run; controlling, by the control unit, a metering device of the liquid chromatography system, the metering device includes a syringe and a plunger, the plunger is configured to be guided in a pressure-tight and displaceable manner, wherein controlling the metering device is accomplished by moving the plunger within the syringe, the metering device further including a variable pump volume V defined by the plunger, to adjust the pump volume V by adjusting a position of the plunger within the syringe, in which the adjusted volume is equal to the calculated difference of the gradient delay volume; and performing the chromatography run on the liquid chromatography system using the adjusted volume and a solvent gradient, the liquid chromatography system further comprising the injection valve, a pump connected to the injection valve, a separation column connected to the injection valve, and a sample loop extending between a pair of sample loop ports of the injection valve, wherein the sample loop comprises the pump volume V of the metering device.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 93.0
- Lexical Diversity: 2.12727
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14661793', '15596738', '15190529', '15959848', '12863976']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7564346746945986
- 35 USC 102 Novelty (BERT): 0.6185687987450118
- Combined Prediction Score: 0.7426480870996399
- Mean Citation Score: 316.82001
- Max Citation Score: 542.0582
- Similarity Product: 536.2622227320077

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test