PATENT CLAIM ANALYSIS

Application Number: 15761081
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "622000"]

Abstract:
The present disclosure describes a method of treating p53-deficient cells using a niclosamide derivative according to formula (I). The present disclosure further describes a method of treating cancer using the compound according to formula I, as well as methods of screening to identify a compound that selectively target cells wherein p53 is deficient or non-functional.

Claim (Index 18):
The method of  claim 1 , wherein the cancer is selected from a group consisting of leukemia, lymphoma, myeloma, skin cancer such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC) or melanoma, breast cancer, head and neck cancer, such as brain cancer, colorectal cancer, colon cancer, rectal cancer, lung cancer, such as non-small cell lung cancer (NSCLC), ovarian cancer, renal cancer, prostate cancer, liver cancer, and human papilloma virus (HPV)-associated cancer such as cervical cancer; or wherein the cancer is selected from a group consisting of leukaemia, lymphoma, myeloma, skin cancer such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC) or melanoma, head and neck cancer, such as brain cancer, colorectal cancer, colon cancer, rectal cancer, lung cancer, such as non-small cell lung cancer (NSCLC), ovarian cancer, renal cancer, prostate cancer, liver cancer, and human papilloma virus (HPV)-associated cancer such as cervical cancer.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 90.0
- Lexical Diversity: 1.53846
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14408748', '14901314', '14950033', '12604970', '10716100']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8109106578595141
- 35 USC 102 Novelty (BERT): 0.5131309370924266
- Combined Prediction Score: 0.7811326857828054
- Mean Citation Score: 283.18594799999994
- Max Citation Score: 295.15762
- Similarity Product: 205.4941926856613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test