PATENT CLAIM ANALYSIS

Application Number: 16012635
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["506", "016000"]

Abstract:
Disclosed herein include systems, methods, compositions, and kits for sample identification. A sample indexing composition can comprise, for example, a protein binding reagent associated with a sample indexing oligonucleotide. Different sample indexing compositions can include sample indexing oligonucleotides with different sequences. Sample origin of cells can be identified based on the sequences of the sample indexing oligonucleotides. Sample indexing oligonucleotides can be barcoded using barcoded and lengthened using daisy-chaining primers.

Claim (Index 20):
The method of  claim 17 , wherein the each of the one or more cells comprises a plurality of mRNA target molecules, and wherein:\n step (d) further comprises hybridizing mRNA target molecules from the cell with oligonucleotide probes of the plurality of oligonucleotide probes between the poly(A) tails of the mRNA target molecules and the poly(T) regions of the oligonucleotide probe; step (e) further comprises extending the oligonucleotide probes hybridized to the mRNA target molecules via the hybridization between the poly(A) tails of the mRNA target molecules and the poly(T) regions of the oligonucleotide probes to produce a third plurality of labeled nucleic acids, wherein each of the third plurality of labeled nucleic acid comprises a complementary sequence of one of the mRNA target molecules and a barcode sequence; and step (f) further comprises obtaining sequence information of the third plurality of labeled nucleic acids or a portion thereof to determine the quantity of one or more of the plurality of mRNA target molecules in at least one of the one or more cells.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.81818
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15937713', '15993468', '15055445', '15667125', '15847752']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6234736933660971
- 35 USC 102 Novelty (BERT): 0.6209061998523799
- Combined Prediction Score: 0.6232169440147255
- Mean Citation Score: 477.22066800000016
- Max Citation Score: 676.4635599999998
- Similarity Product: 480.1082762243317

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test