PATENT CLAIM ANALYSIS

Application Number: 15882386
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["549", "462000"]

Abstract:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.

Claim (Index 7):
The compound according to  claim 1 , wherein, in the formula A is (1) (i) a 5- or 6-membered aromatic heterocyclic group or (ii) a 4- to 6-membered non-aromatic heterocyclic group, each of which is optionally substituted by C 1-6  alkyl group(s) optionally substituted by halogen atom(s), or (2) a C 3-10  cycloalkyl group optionally substituted by halogen atom(s); B is a ring selected from wherein X 1 , X 2 , X 3  and X 4  are each independently a carbon atom or a nitrogen atom; at least one of X 1 , X 2 , X 3  and X 4  is a nitrogen atom; Y 1 , Y 2  and Y 3  are each independently a carbon atom, a nitrogen atom, an oxygen atom or a sulfur atom; at least one of Y 1 , Y 2  and Y 3  is a nitrogen atom, an oxygen atom or a sulfur atom; and Z 1 , Z 2 , Z 3  and Z 4  are each independently a carbon atom or a nitrogen atom, which ring is optionally substituted by C 1-6  alkyl group(s); R 1  is a hydrogen atom; R 2  is a hydrogen atom; R 3  is (1) a hydrogen atom, (2) a C 1-6  alkyl group optionally substituted by substituent(s) selected from\n (a) a C 3-10  cycloalkyl group, \n (b) a C 6-14  aryl group optionally substituted by carboxy group(s), \n (c) a 4- to 6-membered non-aromatic heterocyclic group optionally substituted by C 1-6  alkyl group(s) optionally substituted by substituent(s) selected from a carboxy group, and a C 6-14  aryl group optionally substituted by carboxy group(s), and \n (d) a 5- or 6-membered aromatic heterocyclic group optionally substituted by amino group(s), \n (3) a C 3-10  cycloalkyl group optionally substituted by substituent(s) selected from an amino group and a halogen atom or (4) a 4- to 6-membered non-aromatic heterocyclic group optionally substituted by substituent(s) selected from\n (a) a C 1-6  alkyl group optionally substituted by halogen atom(s), \n (b) a C 3-10  cycloalkyl group, \n (c) a C 1-6  alkyl-carbonyl group, and \n (d) a C 3-10  cycloalkyl-carbonyl group; and \n R 4  is a hydrogen atom, or a salt thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.74359
- Patent Class: 549.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15302405', '15467548', '15005574', '14404126', '14902388']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7808625424837587
- 35 USC 102 Novelty (BERT): 0.531263983209266
- Combined Prediction Score: 0.7559026865563094
- Mean Citation Score: 356.25894200000016
- Max Citation Score: 360.23868
- Similarity Product: 277.6203970510769

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test