PATENT CLAIM ANALYSIS

Application Number: 15976665
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "293000"]

Abstract:
Applicant provides formulations and pharmaceutical compositions containing glucocorticoid receptor modulators (GRMs) and suitable for treating diseases including Cushing's syndrome, prostate cancer, breast cancer, and other cancers, liver diseases, depression, dementia, stress disorders, and substance abuse disorders. The GRM may be a non-steroidal GRM, and may be an octahydro azadecalin GRM. In particular, the GRM may be CORT125281, which is: ((4aR,8aS)-1-(4-fluorophenyl)-6-((2-methyl-2H-1,2,3-triazol-4-yl)sulfonyl)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone. Methods of treating diseases including Cushing's syndrome, liver diseases, cancers, and psychiatric disorders by administration of a GRM in such pharmaceutical compositions are also provided.

Claim (Index 16):
A method of treating a condition amenable to treatment with a glucocorticoid receptor modulator (GRM) comprising administering the GRM CORT125281 in a single unit dosage form, wherein said single unit dosage form contains a uniform admixture of CORT125281 and pharmaceutical excipients, and wherein said uniform admixture is a formulation of  claim 1 .

Metadata:
- Claim Count in Document: 34.0
- Percentile: 93.0
- Lexical Diversity: 1.78947
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15627359', '15697878', '15915477', '15565291', '14908157']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.733491393994984
- 35 USC 102 Novelty (BERT): 0.5124729257474655
- Combined Prediction Score: 0.7113895471702322
- Mean Citation Score: 217.26032400000005
- Max Citation Score: 267.54147
- Similarity Product: 170.59367566979168

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test