PATENT CLAIM ANALYSIS

Application Number: 16091567
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["546", "314000"]

Abstract:
The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Claim (Index 31):
A compound of formula (I) or pharmaceutically acceptable salt thereof wherein:\n R 1  is \u2014C 1-3 alkyl or cyclopropyl; \n R 2  is \u2014C 0-4 alkyl-heterocyclyl, \u2014CH 2 CH(OH)-heterocyclyl, or \u2014(CH 2 ) p O-heterocyclyl, wherein each heterocyclyl is optionally substituted by one, two, or three R 5  groups which may be the same or different; \n R 3  is \u2014H, \u2014C 1-4 alkyl, cyclopropyl, fluoro, chloro, \u2014CH 2 F, \u2014C 0-3 alkylOR 10 , or C 0-3 alkylCN; \n R 4  is phenyl or a heteroaryl group, wherein each are optionally substituted by one, two, or three R 6  groups which may be the same or different; \n each R 5  is independently halo, \u2014C 1-4 alkyl, C 3-4 cycloalkyl, \u2014CH 2 CF 3 , \u2014CH 2 CHF 2 , \u2014CH 2 CH 2 F, \u2014OCH 2 CH 2 OR 8 , \u2014C 0-3 alkylOR 8 , \u2014C 0-3 alkylNR 11 R 12 , \u2014NHCH 2 CH 2 OR 8 , \u2014NHCO 2 R 8 , oxo, \u2014CO 2 R 8 , \u2014C(O)R 8 , or \u2014C(O)NR 11 R 12 ; \n each R 6  is independently halo, \u2014C 1-4 alkyl, \u2014C 0-3 alkylOR 7 , oxo, \u2014CO 2 R 8 , \u2014C 0-3 alkylNR 16 R 17 , \u2014C 0-3 alkyl-CONR 16 R 17 , \u2014CN, \u2014SO 2 \u2014C 1-3 alkyl, or \u2014SO 2 NR 16 R 17 ; \n R 7  is \u2014H, \u2014C 1-3 alkyl, \u2014C 2-3 alkylNR 16 R 17 , or \u2014C 2-3 alkylOH; \n R 8  is \u2014H or \u2014C 1-4 alkyl; \n R 10  is \u2014H, \u2014C 1-3 alkyl, \u2014C 2-3 alkylNR 14 R 15 , or \u2014C 2-3 alkylOH; \n R 11  and R 12  are each independently selected from \u2014H and \u2014C 1-3 alkyl; \n or R 11  and R 12  may join together with the nitrogen to which they are attached to form a 4 to 7-membered heterocyclyl optionally substituted by one or two substituents independently selected from \u2014C 1-3 alkyl optionally substituted with up to 3 fluorine atoms, \u2014C 2-4 alkylOH, \u2014OH, and F; \n R 14  and R 15  are each independently selected from \u2014H and \u2014C 1-3 alkyl; \n or R 14  and R 15  may join together with the nitrogen to which they are attached to form a 4 to 7-membered heterocyclyl optionally substituted by one or two substituents independently selected from \u2014C 1-3 alkyl optionally substituted with up to 3 fluorine atoms, \u2014C 2-4 alkylOH, \u2014OH, and F; \n R 16  and R 17  are each independently selected from \u2014H and \u2014C 1-3 alkyl;\n or R 16  and R 17  may join together with the nitrogen to which they are attached to form a 4 to 7-membered heterocyclyl optionally substituted by one or two substituents independently selected from \u2014C 1-3 alkyl optionally substituted with up to 3 fluorine atoms, \u2014C 2-4 alkylOH, \u2014OH, and F; and \n p is an integer selected from 2, 3, or 4.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 97.0
- Lexical Diversity: 1.125
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16091577', '15762229', '15757199', '15766222', '15374047']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8050646714470032
- 35 USC 102 Novelty (BERT): 0.6034748232545044
- Combined Prediction Score: 0.7849056866277533
- Mean Citation Score: 431.95859800000005
- Max Citation Score: 523.9435
- Similarity Product: 480.66564328128095

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test