PATENT CLAIM ANALYSIS

Application Number: 16055525
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["435", "199000"]

Abstract:
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the engineered cleavage half-domains and fusion proteins; and cells comprising said polynucleotides and/or fusion proteins. Also described are methods of using these polypeptides and polynucleotides, for example for targeted cleavage of a genomic sequence.

Claim (Index 2):
The artificial nuclease of  claim 1 , further comprising an additional amino acid substitution at one or more of positions 418, 432, 441, 481, 486, 523, 527 and 559.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 96.0
- Lexical Diversity: 1.71875
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15660072', '14146471', '15160571', '14627812', '13341537']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7073391531886702
- 35 USC 102 Novelty (BERT): 0.6301696668613557
- Combined Prediction Score: 0.6996222045559388
- Mean Citation Score: 597.855348
- Max Citation Score: 602.3968
- Similarity Product: 549.4674236122131

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test