PATENT CLAIM ANALYSIS

Application Number: 16284551
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["552", "610000"]

Abstract:
Compounds and methods of synthesizing oxysterols are provided. The compounds and methods provided allow the oxysterol to be safely produced at a high yield. The compounds and methods provided can produce the oxysterol in a stereoselective manner.

Claim (Index 17):
A method of making an oxysterol, the method comprising reacting a diol having the formula: with borane, hydrogen peroxide and tetrahydrofuran to form the oxysterol or a pharmaceutically acceptable salt, hydrate or solvate thereof having the formula: wherein R 1  and R 2  comprise a hexyl group and the diol comprises (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(S)-2-hydroxyoctan-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 99.0
- Lexical Diversity: 1.48148
- Patent Class: 552.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14962742', '15600375', '15474325', '14962651', '15599577']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7224580724051959
- 35 USC 102 Novelty (BERT): 0.6343116096231577
- Combined Prediction Score: 0.7136434261269922
- Mean Citation Score: 429.942148
- Max Citation Score: 451.769
- Similarity Product: 376.0461984443664

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test