PATENT CLAIM ANALYSIS

Application Number: 16308014
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-08
Patent Classification: ["424", "001890"]

Abstract:
The present invention addresses the problem of providing a technique for detecting a lesion of a heart disease in a non-invasive manner. The present invention provides a non-invasive diagnostic imaging agent for a heart disease, which contains a radioactively labeled compound capable of binding to an aldosterone synthase or a salt thereof as an active ingredient.

Claim (Index 15):
The non-invasive method according to  claim 13 , wherein the radioactively labeled compound is represented by the following general formula (1): wherein R 1  represents a hydrogen atom or CO 2 R a ; R 2  represents a hydrogen atom, a halogen atom or CO 2 R a ; R 3  represents a hydrogen atom or a hydroxyalkyl group having 1 to 10 carbon atoms; R 4  represents a hydrogen atom, a hydroxy group or an alkoxy group having 1 to 10 carbon atoms; R 5  represents a chain alkyl group having 1 to 5 carbon atoms in which a hydrogen atom is optionally replaced with a halogen atom, a cyclic alkyl group having 3 to 5 carbon atoms in which a hydrogen atom is optionally replaced with a halogen atom, a hydroxyalkyl group having 1 to 5 carbon atoms, or an o-, p- or m-halobenzyl group; A represents CH or a nitrogen atom; X 1  and X 3  each independently represent a hydrogen atom or a halogen atom, and X 2  represents a hydrogen atom, a halogen atom or a nitrile group, provided that at least one of X 1 , X 2  and X 3  is a halogen atom; each R a  independently represents an alkyl group having 1 to 10 carbon atoms; and any one of R 2 , R 5 , and X 2  contains a radioactive halogen atom.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.43902
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16211434', '15321972', '15543849', '14345493', '15543857']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7064878721759242
- 35 USC 102 Novelty (BERT): 0.5320463556904809
- Combined Prediction Score: 0.6890437205273799
- Mean Citation Score: 255.15021399999995
- Max Citation Score: 341.4864
- Similarity Product: 286.57103786029813

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test