PATENT CLAIM ANALYSIS

Application Number: 15962673
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["424", "139100"]

Abstract:
The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human GITR and modulate GITR activity, e.g., enhance, activate or induce GITR activity, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as cancer and infectious diseases, by administering an antibody that specifically binds to human GITR and modulates GITR activity e.g., enhances, activates or induces GITR activity.

Claim (Index 210):
The nucleic acid molecule of  claim 206 , wherein the binding between the antibody and a variant GITR is substantially weakened relative to the binding between the antibody and the human GITR, and wherein the variant GITR comprises residues 26-241 of SEQ ID NO: 701, except for the amino acid substitution G63A.

Metadata:
- Claim Count in Document: 135.0
- Percentile: 91.0
- Lexical Diversity: 1.74545
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14724452', '14472116', '15714585', '11389880', '15517867']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7938502820064974
- 35 USC 102 Novelty (BERT): 0.6463192019993385
- Combined Prediction Score: 0.7790971740057815
- Mean Citation Score: 479.718714
- Max Citation Score: 626.9613
- Similarity Product: 593.0533958441914

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test