PATENT CLAIM ANALYSIS

Application Number: 16312063
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["514", "248000"]

Abstract:
Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.

Claim (Index 1):
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: Ring Q1 is selected from aryl and heteroaryl, wherein aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; Ring Q2 is selected from C 3-10  cycloalkyl, heterocyclyl, aryl and heteroaryl, wherein cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; L is selected from a bond, \u2014(CR C1 R D1 ) t \u2014, \u2014C(O)\u2014, \u2014O\u2014, \u2014(CR C1 R D1 ) t O\u2014, \u2014O(CR C1 R D1 ) t , \u2014S\u2014, \u2014S(O) r \u2014, \u2014(CR C1 R D1 ) t S\u2014, \u2014S(CR C1 R D1 ) t \u2014, \u2014N(R A1 )\u2014, \u2014N(R A1 )C(O)\u2014, \u2014C(O)N(R A1 )\u2014, \u2014N(R A1 )C(O)O\u2014, \u2014OC(O)N(R A1 )\u2014, \u2014N(R A1 )C(O)N(R B1 )\u2014, \u2014N(R A1 )S(O) 2 \u2014, \u2014S(O) 2 N(R A1 )\u2014 and \u2014N(R A1 )S(O) 2 N(R B1 )\u2014; W is selected from \u2014C(O)\u2014, \u2014OC(O)\u2014, \u2014NR A1 C(O)\u2014, \u2014C(\u2550S)\u2014, \u2014S(O) r \u2014, \u2014OS(O) r \u2014, and \u2014N(R A1 )S(O) r \u2014; Y is selected from N and CR 6 ; R 1  is selected from hydrogen, C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, heteroaryl-C 1-4  alkyl, wherein alkyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; each R 2  is selected from hydrogen, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, heteroaryl-C 1-4  alkyl, CN, NO 2 , \u2014NR A2 R B2 , \u2014OR A2 , \u2014C(O)R A2 , \u2014C(\u2550NR E2 )R, \u2014C(\u2550N\u2014OR B2 )R A2 , \u2014C(O)OR A2 , \u2014OC(O)R A2 , \u2014C(O)NR A2 R B2 , \u2014NR A2 C(O)R B2 , \u2014C(\u2550NR E2 )NR A2 R B2 , \u2014NR A2 C(\u2550NR E2 )R B2 , \u2014OC(O)NR A2 R B2 , \u2014NR A2 C(O)OR B2 , \u2014NR A2 C(O)NR A2 R B2 , \u2014NR A2 C(S)NR A2 R B2 , \u2014NR A2 C(\u2550NR E2 )NR A2 R B2 , \u2014S(O) r R A2 , \u2014S(O)(\u2550NR E2 )R B2 , \u2014N\u2550S(O)R A2 R B2 , \u2014S(O) 2 OR A2 , \u2014OS(O) 2 R A2 , \u2014NR A2 S(O) r R B2 , \u2014NR A2 S(O)(\u2550NR E2 )R B2 , \u2014S(O) r NR A2 R B2 , \u2014S(O)(\u2550NR E2 )NR A2 R B2 , \u2014NR A2 S(O) 2 NR A2 R B2 , \u2014NR A2 S(O)(\u2550NR E2 )NR A2 R B2 , \u2014P(O)R A2 R B2  and \u2014P(O)(OR A2 )(OR B2 ), wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; R 3  is selected from hydrogen, halogen, C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl and heterocyclyl-C 1-4  alkyl, wherein alkyl, cycloalkyl and heterocyclyl, are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; R 4  is selected from hydrogen, halogen, C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, and heteroaryl-C 1-4  alkyl, wherein alkyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; R 5  is selected from hydrogen, halogen, C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl and heterocyclyl-C 1-4  alkyl, wherein alkyl, cycloalkyl and heterocyclyl, are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; or R 3  and R 5  taken together form a bond; R 6  is selected from hydrogen, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, heteroaryl-C 1-4  alkyl, CN, NO 2 , \u2014NR A3 R B3 , \u2014OR A3 , \u2014C(O)R A3 , \u2014C(\u2550NR E3 )R A3 , \u2014C(\u2550N\u2014OR B3 )R A3 , \u2014C(O)OR A3 , \u2014OC(O)R A3 , \u2014C(O)NR A3 R B3 , \u2014NR A3 C(O)R B3 , \u2014C(\u2550NR E3 )NR A3 R B3 , \u2014NR A3 C(\u2550NR E3 )R B3 , \u2014OC(O)NR A3 R B3 , \u2014NR A3 C(O)OR B3 , \u2014NR A3 C(O)NR A3 R B3 , \u2014NR A3 C(S)NR A3 R B3 , \u2014NR A3 C(\u2550NR E3 )NR A3 R B3 , \u2014S(O) r R A3 , \u2014S(O)(\u2550NR E3 )R B3 , \u2014N\u2550S(O)R A3 R B3 , \u2014S(O) 2 OR A3 , \u2014OS(O) 2 R A3 , \u2014NR A3  S(O) r R B3 , \u2014NR A3  S(O)(\u2550NR E3 )R B3 , \u2014S(O) r NR A3 R B3 , \u2014S(O)(\u2550NR E3 )NR A3 R B3 , \u2014NR A3 S(O) 2 NR A3 R B3 , \u2014NR A3 S(O)(\u2550NR E3 )NR A3 R B3 , \u2014P(O)R A3 R B3  and \u2014P(O)(OR A3 )(OR B3 ), wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; each R A1 , R A2 , R A3 , R B1 , R B2  and R B3  are independently selected from hydrogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; or each \u201cR A1  and R B1 \u201d, \u201cR A2  and R B2 \u201d or \u201cR A3  and R B3 \u201d together with the atom(s) to which they are attached form a heterocyclic ring of 4 to 12 members containing 0, 1, or 2 additional heteroatoms independently selected from oxygen, sulfur and nitrogen, and optionally substituted with 1 2 or 3 R X  groups; each R C1  and R D1  are independently selected from hydrogen, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R X ; or R C1  and R D1  together with the carbon atom(s) to which they are attached form a ring of 3 to 12 members containing 0, 1 or 2 heteroatoms independently selected from oxygen, sulfur and nitrogen, and optionally substituted with 1 2 or 3 R X  groups; each R E2  and R E3  are independently selected from hydrogen, C 1-10  alkyl, CN, NO 2 , \u2014OR a1 , \u2014SR a1 , \u2014S(O) r R a1 , \u2014C(O)R a1 , \u2014C(O)OR a1 , \u2014C(O)NR a1 R b1  and \u2014S(O) r NR a1 R b1 ; each R X  is independently selected from hydrogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, heteroaryl-C 1-4  alkyl, halogen, CN, NO 2 , \u2014(CR c1 R d1 ) t NR a1 R b1 , \u2014(CR c1 R d1 ) t OR b1 , \u2014(CR c1 R d1 ) t C(O)R a1 , \u2014(CR c1 R d1 ) t C(\u2550NR e1 )R a1 , \u2014(CR c1 R d1 ) t C(\u2550N\u2014OR b1 )R a1 , \u2014(CR c1 R d1 ) t C(O)OR b1 , \u2014(CR c1 R d1 ) t OC(O)R b1 , \u2014(CR c1 R d1 ) t C(O)NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 C(O)R b1 , \u2014(CR c1 R d1 ) t C(\u2550NR e1 )NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 C(\u2550NR e1 )R b1 , \u2014(CR c1 R d1 ) t OC(O)NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 C(O)OR b1 , \u2014(CR c1 R d1 ) t NR a1 C(O)NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 C(S)NR a1 R b1 , \u2014(CR c1 R d1 ) t  NR a1 C(\u2550NR e1 )NR a1 R b1 , \u2014(CR c1 R d1 ) t S(O) r R b1 , \u2014(CR c1 R d1 ) t S(O)(\u2550NR e1 )R b1 , \u2014(CR c1 R d1 ) t N\u2550S(O)R a1 R b1 , \u2014(CR c1 R d1 ) t S(O) 2 OR b1 , \u2014(CR c1 R d1 ) t OS(O) 2 R b1 , \u2014(CR c1 R d1 ) t NR a1 S(O) r R b1 , \u2014(CR c1 R d1 ) t NR a1 S(O)(\u2550NR e1 )R b1 , \u2014(CR c1 R d1 ) t S(O) r NR a1 R b1 , \u2014(CR c1 R d1 ) t S(O)(\u2550NR e1 )NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 S(O) 2 NR a1 R b1 , \u2014(CR c1 R d1 ) t NR a1 S(O)(\u2550NR e1 )NR a1 R b1 , \u2014(CR c1 R d1 ) t P(O)R a1 R b1  and \u2014(CR c1 R d1 ) t P(O)(OR a1 )(OR b1 ), wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R Y ; each R a1  and each R b1  are independently selected from hydrogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R Y ; or R a1  and R b1  together with the atom(s) to which they are attached form a heterocyclic ring of 4 to 12 members containing 0, 1 or 2 additional heteroatoms independently selected from oxygen, sulfur, nitrogen and phosphorus, and optionally substituted with 1, 2 or 3 R Y  groups; each R c1  and each R d1  are independently selected from hydrogen, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from R Y ; or R c1  and R d1  together with the carbon atom(s) to which they are attached form a ring of 3 to 12 members containing 0, 1 or 2 heteroatoms independently selected from oxygen, sulfur and nitrogen, and optionally substituted with 1, 2 or 3 R Y  groups; each R e1  is independently selected from hydrogen, C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, CN, NO 2 , \u2014OR a2 , \u2014SR a2 , \u2014S(O) r R a2 , \u2014C(O)R a2 , \u2014C(O)OR a2 , \u2014S(O) r NR a2 R b2  and \u2014C(O)NR a2 R b2 ; each R Y  is independently selected from C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl, heteroaryl-C 1-4  alkyl, halogen, CN, NO 2 , \u2014(CR c2 R d2 ) t NR a2 R b2 , \u2014(CR c2 R d2 ) t OR b2 , \u2014(CR c2 R d2 ) t C(O)R a2 , \u2014(CR c2 R d2 ) t C(\u2550NR e2 )R a2 , \u2014(CR c2 R d2 ) t C(\u2550N\u2014OR b2 )R a2 , \u2014(CR c2 R d2 ) t C(O)OR b2 , \u2014(CR c2 R d2 ) t OC(O)R b2 , \u2014(CR c2 R d2 ) t C(O)NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 C(O)R b2 , \u2014(CR c2 R d2 ) t C(\u2550NR e2 )NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 C(\u2550NR e2 )R b2 , \u2014(CR c2 R d2 ) t OC(O)NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 C(O)OR b2 , \u2014(CR c2 R d2 ) t NR a2 C(O)NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 C(S)NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 C(\u2550NR e2 )NR a2 R b2 , \u2014(CR c2 R d2 ) t S(O) r R b2 , \u2014(CR c2 R d2 ) t S(O)(\u2550NR e2 )R b2 , \u2014(CR c2 R d2 ) t N\u2550S(O)R a2 R b2 , \u2014(CR c2 R d2 ) t S(O) 2 OR b2 , \u2014(CR c2 R d2 ) t OS(O) 2 R b2 , \u2014(CR c2 R d2 )NR a2 S(O) r R b2 , \u2014(CR c2 R d2 ) t NR a2 S(O)(\u2550NR e2 )R b2 , \u2014(CR c2 R d2 ) t S(O) r NR a2 R b2 , \u2014(CR c2 R d2 ) S(O)(\u2550NR e2 )NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 S(O) 2 NR a2 R b2 , \u2014(CR c2 R d2 ) t NR a2 S(O)(\u2550NR e2 )NR a2 R b2 , \u2014(CR c2 R d2 ) t P(O)R a2 R b2  and \u2014(CR c2 R d2 ) t P(O)(OR a2 )(OR b2 ), wherein alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from OH, CN, amino, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, C 1-10  alkylamino, C 3-10  cycloalkylamino and di(C 1-10  alkyl)amino; each R 2  and each R b2  are independently selected from hydrogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, C 1-10  alkylamino, C 3-10  cycloalkylamino, di(C 1-10  alkyl)amino, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, cycloalkoxy, alkylthio, cycloalkylthio, alkylamino, cycloalkylamino, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from halogen, CN, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, OH, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, amino, C 1-10  alkylamino, C 3-10  cycloalkylamino and di(C 1-10  alkyl)amino; or R a2  and R b2  together with the atom(s) to which they are attached form a heterocyclic ring of 4 to 12 members containing 0, 1 or 2 additional heteroatoms independently selected from oxygen, sulfur, nitrogen and phosphorus, and optionally substituted with 1 or 2 substituents, independently selected from halogen, CN, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, OH, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, amino, C 1-10  alkylamino, C 3-10  cycloalkylamino and di(C 1-10  alkyl)amino; each R c2  and each R d2  are independently selected from hydrogen, halogen, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, C 1-10  alkylamino, C 3-10  cycloalkylamino, di(C 1-10  alkyl)amino, heterocyclyl, heterocyclyl-C 1-4  alkyl, aryl, aryl-C 1-4  alkyl, heteroaryl and heteroaryl-C 1-4  alkyl, wherein alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, cycloalkoxy, alkylthio, cycloalkylthio, alkylamino, cycloalkylamino, heterocyclyl, aryl and heteroaryl are each unsubstituted or substituted with at least one substituent, such as one, two, three or four substituents, independently selected from halogen, CN, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, OH, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, amino, C 1-10  alkylamino, C 3-10  cycloalkylamino and di(C 1-10  alkyl)amino; or R c2  and R d2  together with the carbon atom(s) to which they are attached form a ring of 3 to 12 members containing 0, 1 or 2 heteroatoms independently selected from oxygen, sulfur and nitrogen, and optionally substituted with 1 or 2 substituents, independently selected from halogen, CN, C 1-10  alkyl, C 2-10  alkenyl, C 2-10  alkynyl, C 3-10  cycloalkyl, OH, C 1-10  alkoxy, C 3-10  cycloalkoxy, C 1-10  alkylthio, C 3-10  cycloalkylthio, amino, C 1-10  alkylamino, C 3-10  cycloalkylamino and di(C 1-10  alkyl)amino; each R e2  is independently selected from hydrogen, CN, NO 2 , C 1-10  alkyl, C 3-10  cycloalkyl, C 3-10  cycloalkyl-C 1-4  alkyl, C 1-10  alkoxy, C 3-10  cycloalkoxy, \u2014C(O)C 1-4  alkyl, \u2014C(O)C 3-10  cycloalkyl, \u2014C(O)OC 1-4  alkyl, \u2014C(O)OC 3-10  cycloalkyl, \u2014C(O)N(C 1-4  alkyl) 2 , \u2014C(O)N(C 3-10  cycloalkyl) 2 , \u2014S(O) 2 C 1-4  alkyl, \u2014S(O) 2 C 3-10  cycloalkyl, \u2014S(O) 2 N(C 1-4  alkyl) 2  and \u2014S(O) 2 N(C 3-10  cycloalkyl) 2 ; n is selected from 0, 1, 2, 3 and 4; p is selected from 0, 1 and 2; each r is independently selected from 1 and 2; each t is independently selected from 1, 2, 3 and 4.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 98.0
- Lexical Diversity: 1.08333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15763095', '12598912', '14418484', '13859569', '15676852']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8251986392433869
- 35 USC 102 Novelty (BERT): 0.5470697461770098
- Combined Prediction Score: 0.7973857499367493
- Mean Citation Score: 406.030806
- Max Citation Score: 412.5569
- Similarity Product: 306.2298859002828

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test