PATENT CLAIM ANALYSIS

Application Number: 15893094
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["530", "350000"]

Abstract:
The present disclosure provides compositions including recombinant K1-5 bacteriophages, methods for making the same, and uses thereof. The recombinant K1-5 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.

Claim (Index 20):
A method for determining the antibiotic susceptibility of a bacterial strain or species in a test sample obtained from a subject comprising\n (a) infecting a plurality of test samples comprising bacterial cells with the recombinant K1-5 bacteriophage of  claim 8  and an antibiotic, wherein the plurality of test samples is derived from the subject; (b) detecting the expression of the reporter protein of the recombinant K1-5 bacteriophage in the plurality of test samples; and (c) determining that the antibiotic is effective in inhibiting the bacterial strain or species in a test sample when the reporter protein expression levels of the recombinant K1-5 phage infected bacterial cells in the test sample are reduced relative to that observed in an untreated control sample comprising bacterial cells, wherein the untreated control sample is derived from the subject.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 1.25714
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15893104', '15420936', '15179912', '15507176', '15060424']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5841974951473318
- 35 USC 102 Novelty (BERT): 0.6207731301329005
- Combined Prediction Score: 0.5878550586458886
- Mean Citation Score: 439.2102880000001
- Max Citation Score: 709.44403
- Similarity Product: 476.247193620832

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test