PATENT CLAIM ANALYSIS

Application Number: 16075528
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "560000"]

Abstract:
The present invention relates to a class of fatty acid compounds, a preparation method thereof and use thereof. The fatty acid compounds have the structure of the formula I, which has the ability to activate APMK and inhibit the glucose output in mouse primary hepatocytes. The fatty acid compounds can be used in preparing a medicament for the treatment of obesity or diabetes.

Claim (Index 8):
A method for preparing the fatty acid compound represented by following formula I according to  claim 1 , the method comprises the following steps: (1) reacting sodium acetylide A11 with bromo A12 in DMF to obtain intermediate A13; (2) condensing alkynyl compound A13 and brominated compound A2 in the presence of n-butyl lithium and hexamethylphosphoric triamide to give intermediate A14; (3) refluxing intermediate A14 with lithium bromide in an organic solvent to give intermediate A15; (4) condensing A15 with A16 or A17 in the presence of lithium diisopropylamide to obtain intermediate A18; (5) conducting A18 a hydrogenation reaction to obtain intermediate A19; (6) under alkaline conditions, conducting A19 a hydrolysis reaction and acidulating by dilute hydrochloric acid to obtain A20; the definitions of R 3 , R 4 , R 5 , R 6 , n and m are the same as described in  claim 1 .

Metadata:
- Claim Count in Document: 6.0
- Percentile: 96.0
- Lexical Diversity: 1.51111
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15326310', '15109101', '14398643', '15505052', '09972743']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7913048754376154
- 35 USC 102 Novelty (BERT): 0.5197132131470426
- Combined Prediction Score: 0.7641457092085582
- Mean Citation Score: 300.82333
- Max Citation Score: 318.17914
- Similarity Product: 240.2293266480458

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test