PATENT CLAIM ANALYSIS

Application Number: 16179672
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "210210"]

Abstract:
The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Claim (Index 1):
A compound, or a pharmaceutically acceptable salt, hydrate or solvate thereof, of Formula (I): wherein:\n R 1  is selected from the group consisting of \u2014CO 2 R 4 , \u2014C 1 -C 5 -alkylCO 2 R 4 , \u2014C 3 -C 6 -cycloalkylCO 2 R 4 , \u2014NHCO 2 R 4 , \u2014N(C 1 -C 5 alkyl)CO 2 R 4 , or \u2014OCO 2 R 4 ; \n R 2  is selected from the group consisting of hydrogen, \u2014C 1 -C 4 alkyl, \u2014C 3-6 cycloalkyl, or \u2014C 1 -C 4 alkyl-C 3-6 cycloalkyl; \n R 3  is independently selected from the group consisting of \u2014C 1 -C 4 alkyl, \u2014C 1 -C 4 alkyl-C 3 -C 6 -cycloalkyl, \u2014C 1 -C 4 alkyl-C 4 -C 6 -heterocycyl, \u2014C(O)C 1 -C 4 -alkyl, \u2014C(O)CH 2 CN, \u2014CH 2 CH 2 CN, or \u2014CO 2 -alkyl where the alkyl, heterocycyl or cycloalkyl groups may optionally be substituted by one or more groups selected from halogen, \u2014OH, \u2014O\u2014C 1 -C 5 alkyl, \u2014SO 2 C 1 -C 4 alkyl, \u2014C 1 -C 4 alkyl-OMe, \u2014C 1 -C 4 alkyl-CF 3 , \u2014C 1 -C 4 alkyl-CN, alkyne, cycloalkyl, or heterocycyl; \n R 4  is independently selected from the group consisting of \u2014C 1 -C 5 -alkyl, or \u2014C 3 -C 6 -cycloalkyl where the alkyl or cycloalkyl groups may optionally be substituted by one or more groups selected from halogen, \u2014OH, or \u2014O\u2014C 1 -C 5  alkyl.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 98.0
- Lexical Diversity: 1.34091
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15672627', '15320120', '15377214', '14924427', '15585626']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7999558250896555
- 35 USC 102 Novelty (BERT): 0.493043129434536
- Combined Prediction Score: 0.7692645555241435
- Mean Citation Score: 229.845596
- Max Citation Score: 234.2343
- Similarity Product: 176.9544264882803

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test