PATENT CLAIM ANALYSIS

Application Number: 15980428
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["424", "193100"]

Abstract:
Aspects of the invention relate to spherical nucleic acid-based constructs and related methods and compositions thereof. The compositions of the invention are useful for activating agonists of nucleic acid interacting complexes, such as TLRs, stimulating an immune response, and treating diseases such as infectious disease, cancer, allergies, allergic diseases, and autoimmune disease

Claim (Index 13):
A method for activating a TLR comprising delivering to a cell a nanoscale construct, wherein the nanoscale construct comprises a corona having an exterior shell composed of nucleic acid molecules arranged in a geometrical position and forming a spherical shape around a nanoparticle core, wherein the nucleic acid molecules are CpG oligonucleotides, and wherein the nanoscale construct is about 1 nm to about 40 nm in mean diameter, and wherein the nanoparticle core at the center of the corona is not metallic.

Metadata:
- Claim Count in Document: 76.0
- Percentile: 93.0
- Lexical Diversity: 1.46341
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15315538', '15135216', '13741271', '11084777', '15818509']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6036133592479137
- 35 USC 102 Novelty (BERT): 0.5112855538114913
- Combined Prediction Score: 0.5943805787042715
- Mean Citation Score: 243.54096
- Max Citation Score: 273.97302
- Similarity Product: 185.9162170463848

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test