PATENT CLAIM ANALYSIS

Application Number: 15892295
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "044000"]

Abstract:
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.

Claim (Index 75):
A polynucleotide according to  claim 71 , wherein the encoded HSV1-TK is mutated at amino acid residue 32 and at least one of amino acid residues 25, 26, or 168, wherein the amino acid residues correspond to positions 25, 26, 32, and 168 of SEQ ID NO: 2.

Metadata:
- Claim Count in Document: 83.0
- Percentile: 88.0
- Lexical Diversity: 1.275
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14214522', '14214448', '15516012', '10457604', '15211586']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7415494902277111
- 35 USC 102 Novelty (BERT): 0.7011079011700001
- Combined Prediction Score: 0.7375053313219401
- Mean Citation Score: 426.671468
- Max Citation Score: 831.2875
- Similarity Product: 686.5252314373851

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test