PATENT CLAIM ANALYSIS

Application Number: 16433743
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-09
Patent Classification: ["544", "328000"]

Abstract:
The present invention relates to a process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I) and to a process for purifying the crude product of the compound of the formula (I) for use as pharmaceutically active compound, where, for purification, methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate sulphinyldimethane (1:1), i.e. a compound of the formula (II), is isolated as intermediate or is generated as intermediate in this purification process, if appropriate present in a mixture.

Claim (Index 2):
Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I), characterized in that 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4,5,6-pyrimidinetriamine of the formula (VIII) is reacted with\n a) methyl chloroformate of the formula (V) or b) dimethyl dicarbonate of the formula (X) to give methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinylcarbamate of the formula (VI) via a pyridine-free reaction route.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 100.0
- Lexical Diversity: 2.10909
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16000382', '12955510', '12955864', '13945639', '14295922']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8374401657891755
- 35 USC 102 Novelty (BERT): 0.5623402145970557
- Combined Prediction Score: 0.8099301706699635
- Mean Citation Score: 427.114352
- Max Citation Score: 451.80133
- Similarity Product: 414.8356403127253

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test