PATENT CLAIM ANALYSIS

Application Number: 15920161
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["435", "006110"]

Abstract:
The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample.

Claim (Index 91):
An acellular in vitro method of detecting a single stranded target RNA in a sample comprising a plurality of RNAs, the method comprising:\n (a) contacting the sample in vitro with:\n (i) a C2c2 guide RNA that hybridizes with the single stranded target RNA; \n (ii) a labeled detector RNA; and \n (iii) a C2c2 protein that cleaves the labeled detector RNA; and \n (b) measuring a detectable signal produced by cleavage of the labeled detector RNA wherein said measuring provides for detection of the single-stranded target RNA in the sample, wherein the single stranded target RNA is from a virus, a parasite, a helminth, a fungus, a protozoan, a bacterium, an archaeal cell, or a eukaryotic cell.

Metadata:
- Claim Count in Document: 122.0
- Percentile: 90.0
- Lexical Diversity: 1.84615
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15467922', '15920222', '15917546', '15917549', '15897089']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6633564513021294
- 35 USC 102 Novelty (BERT): 0.6258612619137354
- Combined Prediction Score: 0.6596069323632899
- Mean Citation Score: 463.00478200000015
- Max Citation Score: 612.129
- Similarity Product: 537.2014272682071

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test