PATENT CLAIM ANALYSIS

Application Number: 16072456
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "141000"]

Abstract:
This invention relates to drug conjugates useful for localized treatment of diseases or disorders of the middle ear and/or inner ear. Methods of treating diseases or disorders of the middle ear and/or inner ear, pharmaceutical compositions comprising the conjugates, and methods of inhibiting a Tropomyosin receptor kinase are also provided.

Claim (Index 1):
A conjugate of Formula I:\n B p -M-L-Z-D or a pharmaceutically acceptable salt thereof, wherein:\n B p  is a phosphonate moiety; \n Z is NH or O; \n M is a C 1-6  alkylamino group substituted by 1, 2, 3, or 4 OR C  groups; \n each R C  is independently selected from the group consisting of H, C 1-6  alkyl, C 2-6  alkenyl, and C 2-6  alkynyl; \n L is a linking group; and \n D is a therapeutic agent.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 95.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15631933', '11833964', '14061261', '12513436', '13098393']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7670929728168435
- 35 USC 102 Novelty (BERT): 0.506847200474291
- Combined Prediction Score: 0.7410683955825883
- Mean Citation Score: 199.526208
- Max Citation Score: 210.80957
- Similarity Product: 131.79777320343376

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test