PATENT CLAIM ANALYSIS

Application Number: 16325610
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["435", "232000"]

Abstract:
Provided herein is a genetically modified host cell comprising a heterologous nucleic acid encoding a biofilm dispersal polypeptide that decreases intracellular c-di-GMP levels and enhances the production of lysine and lysine derivatives. Further provided are methods of generating such cell and producing lysine and lysine derivatives using the genetically modified host cell.

Claim (Index 21):
A method of engineering a host cell to increase production of an amino acid or an amino acid derivative, the method comprising introduce a heterologous nucleic acid encoding an biofilm dispersal polypeptide that decreases intracellular c-di-GMP levels into the host cell, wherein the host cell has at least one additional genetic modification to increase production of an amino acid or an amino acid derivative compared to a wildtype host cell; and\n culturing the host cell under conditions in which the heterologous biofilm dispersal polypeptide is expressed, wherein expression of the biofilm dispersal polypeptide increases the production of an amino acid or an amino acid derivative relative to a counterpart control host cell that has not been modified to express the heterologous nucleic acid.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 1.45946
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15774820', '15517633', '12772538', '12993399', '09722441']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5761094015276456
- 35 USC 102 Novelty (BERT): 0.5625119539850111
- Combined Prediction Score: 0.5747496567733821
- Mean Citation Score: 317.812236
- Max Citation Score: 459.55585
- Similarity Product: 333.35708890062574

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test