PATENT CLAIM ANALYSIS

Application Number: 15889788
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["435", "252000"]

Abstract:
The invention provides a non-naturally occurring microbial organism having an acetyl-CoA pathway and the capability of utilizing syngas or syngas and methanol. In one embodiment, the invention provides a non-naturally occurring microorganism, comprising one or more exogenous proteins conferring to the microorganism a pathway to convert CO, CO 2  and/or H 2  to acetyl-coenzyme A (acetyl-CoA), methyl tetrahydrofolate (methyl-THF) or other desired products, wherein the microorganism lacks the ability to convert CO or CO 2  and H 2  to acetyl-CoA or methyl-THF in the absence of the one or more exogenous proteins. For example, the microbial organism can contain at least one exogenous nucleic acid encoding an enzyme or protein in an acetyl-CoA pathway. The microbial organism is capable of utilizing synthesis gases comprising CO, CO 2  and/or H 2 , alone or in combination with methanol, to produce acetyl-CoA. The invention additionally provides a method for producing acetyl-CoA, for example, by culturing an acetyl-CoA producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an acetyl-CoA pathway enzyme or protein in a sufficient amount to produce acetyl-CoA, under conditions and for a sufficient period of time to produce acetyl-CoA.

Claim (Index 195):
The microorganism of  claim 192  wherein said microbial organism further comprises an exogenous nucleic acid encoding a hydrogenase, wherein said hydrogenase extracts reducing equivalents from H 2 .

Metadata:
- Claim Count in Document: 23.0
- Percentile: 88.0
- Lexical Diversity: 2.54118
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13615168', '13106764', '12358217', '12875068', '13920927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5038384447051181
- 35 USC 102 Novelty (BERT): 0.5793991437915434
- Combined Prediction Score: 0.5113945146137606
- Mean Citation Score: 499.89735
- Max Citation Score: 524.90967
- Similarity Product: 377.5402599392295

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test