PATENT CLAIM ANALYSIS

Application Number: 15767551
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["435", "205000"]

Abstract:
The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Claim (Index 9):
The variant of  claim 1 , wherein the variant comprises at least one of the following substitutions or combinations of substitutions:\n T43K; D4R; S5V; I13S; K15R; V18M; V85G; S95P+A121P+Y295W+T43K; T43K+S95P+A121P+Y295W+Q318Y; V18M+T43K+S95P+A121P+Y295W+Q318Y; D4R+T43K+S95P+A121P+Y295W+Q318Y; S5V+T43K+S95P+A121P+Y295W+Q318Y; I13S+T43K+S95P+A121P+Y295W+Q318Y; V18M+T43K+S95P+A121P+Y295W; and wherein the variant has glucoamylase activity and wherein the variant has at least 85%, but less than 100% sequence identity to the polypeptide of SEQ ID NO: 3, and wherein the variants have increased specific activity and/or increased melting temperature measured by TSA of at least 2\u00b0 C. compared to the glucoamylase of SEQ ID NO: 3.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 91.0
- Lexical Diversity: 1.89394
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14787418', '14901953', '14426051', '14773673', '15112096']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6415914498496169
- 35 USC 102 Novelty (BERT): 0.5535389198083538
- Combined Prediction Score: 0.6327861968454906
- Mean Citation Score: 367.950342
- Max Citation Score: 422.01895
- Similarity Product: 310.26888032301963

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test