PATENT CLAIM ANALYSIS

Application Number: 16003990
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["546", "081000"]

Abstract:
The present invention relates to compounds of formulas III and V that are useful as pharmaceutical agents, particularly as autophagy inhibitors.

Claim (Index 17):
A compound selected from the group consisting of: Example Structure Name 4 6-Chloro-2-methoxy-N-(4- (pyrrolidin-1-yl)butyl)acridin- 9-amine   10 N 1 -(6-Chloro-2- methoxyacridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   12 N 1 -(6-Chloro-2- methoxyacridin-9-yl)-N 4 - cyclopropyl-N 4 -ethylbutane- 1,4-diamine   13 N 1 -(6-Chloro-2- methoxyacridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - ethylbutane-1,4-diamine   30 N 1 -(acridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   31 N 1 -(cyclopropylmethyl)-N 4 - (2-fluoroacridin-9-yl)-N 1 - methylbutane-1,4-diamine   32 N 1 -(2-chloroacridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   33 N 1 -(cyclopropylmethyl)-N 4 - (2-methoxyacridin-9-yl)-N 1 - methylbutane-1,4-diamine   34 N 1 -(6-bromo-2- methoxyacridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   35 N 1 -(cyclopropyl-methyl)-N 4 - (6-fluoro-2-methoxyacridin-9- yl)-N 1 -methylbutane-1,4- diamine   36 N 1 -(6-chloro-2-fluoroacridin- 9-yl)-N 4 -(cyclopropylmethyl)- N 4 -methylbutane-1,4-diamine   37 N 1 -(cyclopropylmethyl)-N 4 - (2,6-dichloroacridin-9-yl)-N 1 - methylbutane-1,4-diamine   38 N 1 -(3-chloroacridin-9-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   39 7-chloro-10-(4-((cyclopropyl- methyl)(methyl)amino)butylamino) benzo[b][1,5]naphthyridin- 2-ol   40 N 1 -(7-chlorobenzo[b][1,5] naphthyridin-10-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   41 N 1 -(cyclopropylmethyl)-N 4 -(2,7- dichlorobenzo[b][1,5]naphthyridin- 10-yl)-N 1 -methylbutane-1,4- diamine   42 N 1 -(7-chloro-2-methoxybenzo[b] [1,5]naphthyridin-10-yl)-N 4 - (cyclopropylmethyl)-N 4 - methylbutane-1,4-diamine   47 N 4 -(6-chloro-2-methoxyacridin- 9-yl)-N 1 -(cyclopropylmethyl)-N 1 - methylpentane-1,4-diamine   48 N 4 -(6-chloro-2-methoxyacridin-9- yl)-N 1 -(cyclopropylmethyl)-N 1 - methylhexane-1,4-diamine   49 N 4 -(6-chloro-2-methoxyacridin-9- yl)-N 1 -(cyclopropylmethyl)-5- methoxy-N 1 -methylpentane-1,4- diamine   53 N-(4-(6-chloro-2-methoxyacridin- 9-ylamino)butyl)-N- (cyclopropylmethyl) methanesulfonamide   54 N 1 -(6-chloro-2- methoxyacridin-9-yl)-N 4 - (cyclopropylmethyl)butane- 1,4-diamine   56 N 1 -(6-chloro-2-methoxyacridin-9- yl)-N 4 -cyclopropyl-N 4 - methylbutane-1,4-diamine   64 6-chloro-2-methoxy-N-(4- morpholinobutyl)acridin-9- amine

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.04545
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14116650', '15384823', '13995889', '14173072', '12316848']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7667560505871609
- 35 USC 102 Novelty (BERT): 0.5317173458195269
- Combined Prediction Score: 0.7432521801103975
- Mean Citation Score: 256.67405799999995
- Max Citation Score: 352.04474
- Similarity Product: 266.1040600605548

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test