PATENT CLAIM ANALYSIS

Application Number: 16075514
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "254000"]

Abstract:
The present disclosure provides a posaconazole derivative, a pharmaceutical composition and use thereof, which specifically include a compound represented by the following formula (I), a racemate, stereoisomer, tautomer, oxynitride, or a pharmaceutically acceptable salt thereof: The compounds of the present disclosure have strong antifungal activity, high safety, and good water solubility, without the need for the addition of a cosolvent (such as hydroxypropyl-β-cyclodextrin, sulfobutyl ether-β-cyclodextrin, and the like) with potential safety risks. Furthermore, the formulation process of the compound could have less difficulty and less cost, and therefore can be used to prepare improved antifungal drugs.

Claim (Index 3):
The compound, racemate, stereoisomer, tautomer, oxynitride, or pharmaceutically acceptable salt thereof according to  claim 1 , wherein:\n the group that can be converted into a hydroxyl group in vivo can be an ester group that can be converted into a hydroxyl group in vivo, for example, an ester group that can be converted into a hydroxyl group in vivo by hydrolysis and/or enzymatic hydrolysis; the ester groups include polyether ester group, phosphate group, sulfate group, heterocyclic ester group, alkanoate group, alkenoate group, amino acid ester group, carbonate group, or acid ester group; for example, the ester group can be phosphate group, amino acid ester group, carbonate group or acidic ester group.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 96.0
- Lexical Diversity: 1.56
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12226286', '12421230', '15380836', '10984522', '10984093']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.758917353819666
- 35 USC 102 Novelty (BERT): 0.520803238465042
- Combined Prediction Score: 0.7351059422842036
- Mean Citation Score: 272.868316
- Max Citation Score: 278.55414
- Similarity Product: 185.7819790225912

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test