PATENT CLAIM ANALYSIS

Application Number: 16055407
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-04
Patent Classification: ["514", "557000"]

Abstract:
This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This invention also provides pharmaceutical compositions comprising a compound of this invention and the use of such compositions in methods of treating narcolepsy, fibromyalgia, other disorders or conditions that are beneficially treated by improving nocturnal sleep or by administering sodium oxybate.

Claim (Index 2):
A pharmaceutical composition comprising an effective amount of a compound of Formula IV wherein: A is hydrogen, deuterium, \u2014CH 2 \u2014C(O)OR 2  or \u2014CH(R 1 )\u2014C(O)OR 2 ; R 1  is a C 1-6  alkyl, C 2-10  alkoxyalkyl, or C 3-6  cycloalkyl group that is optionally substituted by an R 3  group; R 3  is C 1-3  alkyl, C 1-3  alkoxy, phenyl, \u2014O\u2014(CH 2 CH 2 O) n \u2014CH 3 , or -(heterocyclyl)-C 1-3  alkyl where the heterocyclyl moiety is a four to six-membered ring having an oxygen ring atom; n is 1, 2, or 3; R 2  is hydrogen, deuterium, \u2014C 1-4  alkyl, \u2014C 1-4  alkyl-phenyl, \u2014C 3-6  cycloalkyl, \u2014C 3-6  cycloalkyl-phenyl, \u2014CH 2 \u2014(C 3-6  cycloalkyl), \u2014CH 2 \u2014(C 3-6  cycloalkyl)-phenyl, phenyl, or biphenyl; X is hydrogen, deuterium, \u2014C(O)-indanyl, \u2014C(O)-indenyl, \u2014C(O)-tetrahydronaphthyl, \u2014C(O)\u2014C 1-6  alkyl, \u2014C(O)\u2014C 1-6  alkenyl, \u2014C(O)\u2014C 1-6  alkynyl, \u2014C(O)\u2014C 1-3  alkyl-(C 3-6  cycloalkyl), or \u2014C(O)\u2014C 3-6  cycloalkyl optionally substituted by C 1-6  alkyl, phenyl or naphthyl; and each Y is independently selected from hydrogen and deuterium, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 25.0
- Percentile: 96.0
- Lexical Diversity: 1.32653
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15810526', '13265609', '14732859', '13914127', '14255331']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7603562845036642
- 35 USC 102 Novelty (BERT): 0.4926928941994636
- Combined Prediction Score: 0.7335899454732442
- Mean Citation Score: 245.385108
- Max Citation Score: 256.59006
- Similarity Product: 211.1584819084132

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test