PATENT CLAIM ANALYSIS

Application Number: 16076818
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-05
Patent Classification: ["544", "297000"]

Abstract:
The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.

Claim (Index 1):
A compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein: X is halogen; X\u2032 is H or halogen; Z is NR 2  or O; A is aryl, aroyl, heteroaryl, or heteroaroyl, wherein A is optionally substituted with one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, halo, \u2014OH, alkoxy, \u2014CN, \u2014NR a R b , \u2014N(R a )C(O) alkyl, \u2014N(R a )CO 2 alkyl, \u2014N(R a )SO 2 alkyl, \u2014C(O)alkyl, \u2014CO 2 H, \u2014CO 2 alkyl, \u2014CONR a R b , \u2014SO 2 alkyl, and \u2014SO 2 NR a R b ; wherein R a  and R b  are independently for each occurrence H or alkyl; B is aryl or heteroaryl, wherein B is optionally substituted with one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, halo, \u2014OH, alkoxy, \u2014CN, \u2014NR c R d , \u2014N(R c )C(O) alkyl, \u2014N(R c )CO 2 alkyl, \u2014N(R c )SO 2 alkyl, \u2014C(O)alkyl, \u2014CO 2 H, \u2014CO 2 alkyl, \u2014CONR c R d , \u2014SO 2 alkyl, and \u2014SO 2 NR c R d ; wherein R c  and R d  are independently for each occurrence H or alkyl; E is aryl or heteroaryl, wherein E is optionally substituted with one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, halo, \u2014OH, alkoxy, \u2014CN, \u2014NR e R f , \u2014N(R e )C(O) alkyl, \u2014N(R e )CO 2 alkyl, \u2014N(R e )SO 2 alkyl, \u2014C(O)alkyl, \u2014CO 2 H, \u2014CO 2 alkyl, \u2014CONR e R f , \u2014SO 2 alkyl, and \u2014SO 2 NR e R f ; wherein R e  and R f  are independently for each occurrence H or alkyl; n=1, 2, or 3; R 1  is alkyl; and R 2  is H or alkyl.

Metadata:
- Claim Count in Document: 186.0
- Percentile: 96.0
- Lexical Diversity: 1.40541
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15503131', '16063542', '15299230', '14460289', '13542358']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8264382736712186
- 35 USC 102 Novelty (BERT): 0.5206222312801075
- Combined Prediction Score: 0.7958566694321075
- Mean Citation Score: 321.934548
- Max Citation Score: 347.67532
- Similarity Product: 275.1893994540548

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test