PATENT CLAIM ANALYSIS

Application Number: 15881231
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["514", "183000"]

Abstract:
The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Claim (Index 60):
A method for determining whether a subject has, or is at risk of having, metastatic melanoma, comprising,\n obtaining from the subject a sample; measuring in the sample (i) a first expression level of a metastasis promoter factor selected from the group consisting of miR-199a-3p, miR-199a-5p, miR-1908, and CTGF, or (ii) a second expression level of a metastasis suppressor factor selected from the group consisting of DNAJA4, ApoE, LRP1, LRP8, Liver X Receptor (LXR), and miR-7; and comparing the first expression level with a first predetermined reference value, or the second expression level with a second predetermined reference value; whereby the subject is determined to have, or to be at risk of having, metastatic melanoma if (a) the first expression level is above a first predetermined reference value or (b) the second expression level is below a second predetermined reference value.

Metadata:
- Claim Count in Document: 143.0
- Percentile: 86.0
- Lexical Diversity: 1.22727
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15228643', '14486477', '15650480', '14486466', '14678628']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.868648219683464
- 35 USC 102 Novelty (BERT): 0.6427543849474736
- Combined Prediction Score: 0.846058836209865
- Mean Citation Score: 749.8811079999997
- Max Citation Score: 894.0029
- Similarity Product: 560.0294150253774

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test