PATENT CLAIM ANALYSIS

Application Number: 15752994
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["530", "387300"]

Abstract:
A refolding process of Ranibizumab is disclosed wherein the solubilized solution of heavy chain and/or light chain of Ranibizumab treated with refolding buffer under suitable conditions including pH, temperature and incubation period and the pH and temperature shift is performed at suitable interval to obtain high quality and quantity of refolded protein.

Claim (Index 19):
The process as claimed in  claim 1 , wherein the chaotropic agent is selected from the group consisting of guanidine hydrochloride, urea, and sodium or potassium hydroxide.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 88.0
- Lexical Diversity: 1.35
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13668182', '14922802', '13634801', '11341013', '14766849']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6989889243741739
- 35 USC 102 Novelty (BERT): 0.5221788596935824
- Combined Prediction Score: 0.6813079179061148
- Mean Citation Score: 278.37254
- Max Citation Score: 314.81305
- Similarity Product: 223.3005871416211

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test