PATENT CLAIM ANALYSIS

Application Number: 15744243
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "006140"]

Abstract:
A method of selecting a subject suffering from a cancer for a therapeutic regimen of administration of a pharmaceutical composition comprising an effective amount of an FGFR inhibitor is described, which method comprises (1) the taking of a tumor or liquid biopsy from the subject; (2) determination of the level of expression of any or all of FGFR1, FGFR2 and FGFR3, and (3) comparison of the determined level of expression of at least one of FGFR1, FGFR2 and FGFR3 with a pre-established threshold value, and declaring the subject eligible for the therapeutic regimen if the determined level exceeds the threshold value. The invention also relates to a method of personalized cancer therapy comprising selection of a subject by the above-described method and subjecting the subject to a therapeutic regimen that comprises administration of a pharmaceutical composition comprising an effective amount of an FGFR inhibitor.

Claim (Index 38):
A method of selecting a subject suffering from a gastric cancer for treatment with Compound A, the method comprising determining the level of expression FGFR2 in a tumor or liquid biopsy from the subject and if the determined level of expression of FGFR2 exceeds a pre-established threshold level, considering the subject eligible for treatment.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 86.0
- Lexical Diversity: 2.16438
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12304638', '14048841', '13612044', '13509068', '12652720']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6084646715393114
- 35 USC 102 Novelty (BERT): 0.5142464200535867
- Combined Prediction Score: 0.5990428463907389
- Mean Citation Score: 300.951362
- Max Citation Score: 313.2089200000001
- Similarity Product: 220.79861787966496

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test