PATENT CLAIM ANALYSIS

Application Number: 15981979
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "284000"]

Abstract:
A derivative of isocorydine of formula I: wherein: R 1 ═   X═N, C, C═C; n 1 =0, 1    R 2 ═H, R 1  Y═C, N R 3 ═H, Cl, Br, F, CF 3 , OCH 3 , CH 3 ,   Z ═H, Cl, F, N; n 2 =0, 1  R 4 ═NH 2 , CH 2 NH 2 , NHCO(CH 2 ) n3 CH 3 , CH 2 NHCO(CH 2 ) n3 CH 3 , n 3 =0, 1, 2.   This derivative is prepared by amidation condensation reaction between an amino group of NICD and a carbonyl group of an aryl isocyanate, a carboxylic acid, or an acid chloride, or symmetrical amidation condensation reaction between an NICD and an aromatic amino group by solid phosgene. This derivative has anti-cancer activity in vivo and in vitro, and may be used for preventing and treating cancer.

Claim (Index 1):
An isocorydine derivative having formula I: wherein in formula I: R 1 \u2550 wherein X\u2550N, C, or C\u2550C, n 1 =0 or 1 Y\u2550C or N, Z\u2550H, Cl, F or N; n 1 =0 or 1; R 3 \u2550H, Cl, Br, F, CF 3 , OCH 3 , CH 3 , or R 4 \u2550NH 2 , CH 2 NH 2 , NHCO(CH 2 ) n3 CH 3 , CH 2 NHCO(CH 2 ) n3 CH 3 , n3=0, 1, 2, and R 2 \u2550H, or R 1 .

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 2.28947
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13699869', '15762985', '12767647', '13379497', '14263886']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7378398955323979
- 35 USC 102 Novelty (BERT): 0.5201135632844234
- Combined Prediction Score: 0.7160672623076005
- Mean Citation Score: 271.156108
- Max Citation Score: 283.43286
- Similarity Product: 199.2786271263671

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test