PATENT CLAIM ANALYSIS

Application Number: 16151736
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "011300"]

Abstract:
Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.

Claim (Index 1):
A method for making a microparticle coated with an active agent that is insulin or an insulin analog, the method comprising:\n (i) obtaining a crystalline fumaryl diketopiperazine microparticle wherein the crystalline diketopiperazine microparticle does not comprise an active agent; (ii) forming a suspension comprising said crystalline diketopiperazine microparticle and a solvent; (iii) dissolving said active agent in the fluid phase of said suspension; (iv) increasing the pH of the fluid phase to about 4 to 5; (v) adsorbing of said active agent onto a surface of said crystalline diketopiperazine microparticle to provide a coating of said active agent on said crystalline diketopiperazine microparticle; and (vi) removing or exchanging said solvent after step (v).

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.33333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11532065', '14746656', '12815276', '12883369', '13797657']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8274478857387596
- 35 USC 102 Novelty (BERT): 0.5787149976304375
- Combined Prediction Score: 0.8025745969279274
- Mean Citation Score: 556.980216
- Max Citation Score: 557.8589
- Similarity Product: 391.1451618588745

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test