PATENT CLAIM ANALYSIS

Application Number: 16204748
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-06
Patent Classification: ["546", "290000"]

Abstract:
The present invention includes novel substituted 1-hydroxy-pyridin-2(1H)-ones, which can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention inhibit HBV RNAse H activity.

Claim (Index 1):
A compound, or a salt, solvate, geometric isomer, stereoisomer, tautomer, or any mixtures thereof, selected from the group consisting of: wherein in (A):\n R 1  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n R 2  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n R 3  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n m is 0 or 1; \n R 4  is optionally substituted aryl or heteroaryl; \n and the compound is not (E/Z)-1,6-Dihydroxy-4-methyl-5-(1-(phenoxyimino)ethyl)pyridin-2(1H)-one; \n and wherein in (B):\n R 1  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n R 2  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n R 3  is selected from the group consisting of optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, and optionally substituted C 3 -C 8  cycloalkyl; \n m is 0 or 1; and \n ring A is optionally substituted aryl or heteroaryl.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 98.0
- Lexical Diversity: 1.17073
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16204584', '13796437', '16477533', '15512494', '16070014']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7792797192463602
- 35 USC 102 Novelty (BERT): 0.5210188097009725
- Combined Prediction Score: 0.7534536282918215
- Mean Citation Score: 280.055348
- Max Citation Score: 325.22662
- Similarity Product: 262.19290249236104

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test