PATENT CLAIM ANALYSIS

Application Number: 16037375
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["544", "317000"]

Abstract:
Disclosed are a compound and a pharmaceutical composition that exhibit an excellent drug efficacy against a tumor, in particular a tumor which has acquired resistance to gemcitabine. Specifically, provided is a thionucleoside derivative represented by General (in the formula, R 1  represents a hydroxyl group which may be protected, a C 1-20  alkoxy group which may be substituted, or the like; R 2  represents a C 1-20  alkoxy group which may be substituted, a C 3-8  cycloalkoxy group which may be substituted, or the like; and R 3  represents a hydrogen atom or the like); or a salt thereof. Further, provided is a pharmaceutical composition containing such a thionucleoside derivative or a salt thereof.

Claim (Index 5):
A method for producing a pharmaceutical composition containing a thionucleoside derivative represented by Formula [1]: wherein, in the Formula [1], R 1  represents a hydroxyl group which may be protected, a C 1-20  alkoxy group which may be substituted, a C 3-8  cycloalkoxy group which may be substituted, an aryloxy group which may be substituted, a heterocyclic oxy group which may be substituted, or an amino group which may be substituted; R 2  represents a C 1-20  alkoxy group which may be substituted, a C 3-8  cycloalkoxy group which may be substituted, an aryloxy group which may be substituted, a heterocyclic oxy group which may be substituted, or an amino group which may be substituted; or R 1  and R 2 , together with the phosphorus atom to which they are bonded, may form a 5- to 10-membered nitrogen.phosphorus-containing heterocyclic ring which may be substituted, a 5- to 10-membered oxygen.phosphorus-containing heterocyclic ring which may be substituted, or a 5- to 10-membered nitrogen.oxygen.phosphorus-containing heterocyclic ring; and R 3  represents a hydrogen atom; or R 2  and R 3 , together with the phosphorus atom to which R 2  is bonded, an oxygen atom, methylene, two carbon atoms constituting the tetrahydrothiophene ring and the oxygen atom to which R 3  is bonded, may form a 6 to 10-membered oxygen.phosphorus-containing heterocyclic ring which may be substituted; or a salt thereof.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 95.0
- Lexical Diversity: 2.06349
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15581834', '11816940', '14852738', '14873966', '13198819']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7235369738528529
- 35 USC 102 Novelty (BERT): 0.6663646468066552
- Combined Prediction Score: 0.7178197411482331
- Mean Citation Score: 370.45701
- Max Citation Score: 668.1111
- Similarity Product: 620.197434627986

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test