PATENT CLAIM ANALYSIS

Application Number: 16094243
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["544", "297000"]

Abstract:
The present invention relates to new polymorphic forms of Crystalline Rosuvastatin calcium along with novel processes for crystalline as well as amorphous Rosuvastatin calcium.

Claim (Index 7):
A novel process for the preparation of stable amorphous Rosuvastatin Calcium for the compound 7-[4-(4-flurophenyl)-6-isopropyl-2-(N-methyl-N-methyl sulfonyl amino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid Calcium salt which comprises\n i. Dissolution of new polymorphic form \u2018M\u2019 of Rosuvastatin calcium in halogenated hydrocarbon such as methylene dichloride, chloroform, carbon tetrachloride or mixture therof or an aliphatic ketone such as acetone, ethyl methyl ketone, diethyl ketone, dipropyl ketone, dibutyl ketone or a mixture thereof & water. ii. Recovery of solvent from reaction mass of step (i) to left approximately 5 times the volume w.r.t. the starting material or Rosuvastatin calcium & addition of ant-oxidant/stabilizer like butylated hydroxyanisole, butylated hydroxytoluene or propyl gallate etc. iii. Crystallization of amorphous Rosuvastatin Calcium salt by addition of an aliphatic ether used is selected from Diisopropylether, methyl tert butyl ether, dimethyl ether, diethyl ether or mixture thereof. iv. Isolation & drying of filtered material to get amorphous Rosuvastatin calcium.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 97.0
- Lexical Diversity: 1.13636
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13885509', '12449426', '13574005', '14901721', '13143943']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8279190233087398
- 35 USC 102 Novelty (BERT): 0.5459674720913159
- Combined Prediction Score: 0.7997238681869974
- Mean Citation Score: 386.299474
- Max Citation Score: 421.883
- Similarity Product: 312.85740907400844

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test