PATENT CLAIM ANALYSIS

Application Number: 16040244
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "134100"]

Abstract:
The invention provides antibodies, antibody drug conjugates, antibody-based fragments or antibody fragments (antigen-binding fragments), as well as antibody drug conjugates (ADCs) and chimeric antigen receptors (CARs), that specifically recognize human ROR1 and related compositions. Also provided in the invention are methods of using such antibodies in various diagnostic and therapeutic applications.

Claim (Index 15):
A humanized antibody, antibody-based binding protein or antibody fragment that specifically binds to the extracellular domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1), comprising a heavy chain variable region sequence and a light chain variable region sequence respectively set forth as\n (1) SEQ ID NO:130 and SEQ ID NO:136; (2) SEQ ID NO:131 and SEQ ID NO:137; (3) SEQ ID NO:132 and SEQ ID NO:138; (4) SEQ ID NO:133 and SEQ ID NO:139; (5) SEQ ID NO:134 and SEQ ID NO:140; or (6) SEQ ID NO:135 and SEQ ID NO:141.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 95.0
- Lexical Diversity: 1.46512
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13990977', '14940961', '16027967', '15988659', '14203997']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7960620398143035
- 35 USC 102 Novelty (BERT): 0.5334575244072042
- Combined Prediction Score: 0.7698015882735935
- Mean Citation Score: 362.485876
- Max Citation Score: 381.50797
- Similarity Product: 286.22284567400453

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test