PATENT CLAIM ANALYSIS

Application Number: 16195983
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["540", "495000"]

Abstract:
The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), LRKK2, EphA2, polo kinase 1,2,3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK1, ULK2, PLK4, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and the use of such compounds in the treatment of various diseases, disorders or conditions.

Claim (Index 69):
A compound of formula I: or a pharmaceutically acceptable salt, ester or prodrug thereof, wherein,\n A is a single bond or double bond; \n R\u2032 is H or alkyl; L is absent, S, SO, SO 2 , or CO; X is an optional substituent; R 1  is H, alkyl, alkenyl, alkynyl, each containing 0, 1, 2, or 3 heteroatoms selected from O, S, or N; or R 1  is aryl, arylalkyl, heteroaryl, heterocyclic, or carbocyclic; wherein R 1  may be optionally substituted; R 2  is hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, and optionally substituted heterocyclyl; and R 6  is hydrogen or optionally substituted alkyl.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 98.0
- Lexical Diversity: 1.74157
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14775897', '15581702', '14994213', '15605515', '15231209']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7847029592589978
- 35 USC 102 Novelty (BERT): 0.641461631970479
- Combined Prediction Score: 0.770378826530146
- Mean Citation Score: 599.5996640000002
- Max Citation Score: 681.5889
- Similarity Product: 530.9018818114042

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test