PATENT CLAIM ANALYSIS

Application Number: 16075039
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "382000"]

Abstract:
Formulations for treating burns and burn wound healing comprising a Granzyme B inhibitor and a pharmaceutically acceptable carrier, and methods for treating burns and for burn wound healing using the formulations.

Claim (Index 1):
A formulation for burn wound healing, comprising a compound having Formula (I): stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: R 1  is a heteroaryl group selected from\n (a) 1,2,3-triazolyl, and \n (b) 1,2,3,4-tetrazolyl; \n n is 1 or 2; R 2  is selected from hydrogen, C1-C6 alkyl, and C3-C6 cycloalkyl; R 3  is selected from\n (a) hydrogen, \n (b) C 1 -C 4  alkyl optionally substituted with a carboxylic acid, carboxylate, or carboxylate C 1 -C 8  ester group (\u2014CO 2 H, \u2014CO 2 \u2212 , \u2014C(\u2550O)OC 1 -C 8 ), an amide optionally substituted with an alkylheteroaryl group, or a heteroaryl group; \n Z is an acyl group selected from the group\n (a) \n \u2003and (b) wherein Y is hydrogen, heterocycle, \u2014NH 2 , or C 1 -C 4  alkyl; R 4  is selected from\n (i) C 1 -C 12  alkyl, \n (ii) C 1 -C 6  heteroalkyl optionally substituted with C 1 -C 6  alkyl, \n (iii) C 3 -C 6  cycloalkyl, \n (iv) C 6 -C 10  aryl, \n (v) heterocyclyl, \n (vi) C 3 -C 10  heteroaryl, \n (vii) aralkyl, and \n (viii) heteroalkylaryl; \n R 5  is heteroaryl or \u2014C(\u2550O)\u2014R 10 , wherein R 10  is selected from\n (i) C 1 -C 12  alkyl optionally substituted with C 6 -C 10  aryl, C 1 -C 10  heteroaryl, amino, or carboxylic acid, \n (ii) heteroalkyl optionally substituted with C 1 -C 6  alkyl or carboxylic acid, \n (iii) C 3 -C 6  cycloalkyl optionally substituted with C 1 -C 6  alkyl, optionally substituted C 6 -C 10  aryl, optionally substituted C 3 -C 10  heteroaryl, amino, or carboxylic acid, \n (iv) C 6 -C 10  aryl optionally substituted with C 1 -C 6  alkyl, optionally substituted C 6 -C 10  aryl, optionally substituted C 3 -C 10  heteroaryl, amino, or carboxylic acid, \n (v) heterocyclyl, \n (vi) C 3 -C 10  heteroaryl, \n (vii) aralkyl, and \n (viii) heteroalkylaryl, and \n a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 96.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15500798', '15500781', '14815696', '14869750', '15470596']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7288398059664818
- 35 USC 102 Novelty (BERT): 0.510550416466094
- Combined Prediction Score: 0.707010867016443
- Mean Citation Score: 256.867484
- Max Citation Score: 284.3631
- Similarity Product: 230.84962650990485

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test