PATENT CLAIM ANALYSIS

Application Number: 16098244
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "218000"]

Abstract:
The present invention relates to new compounds of general formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels or dual activity towards subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.

Claim (Index 20):
The compound according to  claim 18 , wherein R 3  represents a \u2014(CH 2 ) p \u2014O\u2014R 4  wherein p is 0, 1 or 2 and wherein R 4  is:\n a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl or ethyl; a tert-butyldimethylsilyl radical; a methylbenzenesulfonate radical; a \u2014CHR 4a R 4b  or a \u2014CH 2 \u2014CHR 4a R 4b  a wherein R 4a  is a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl or isopropyl; or a group selected from: and wherein R 4b  is a \u2014(CH 2 ) j \u2014NR 4b\u2032 R 4b\u2033  being j 0, 1, 2 or 3 and R 4b\u2032  and R 4b\u2033  are independently from one another a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl; a C 1-6  haloalkyl radical; a benzyl group; a phenethyl group; a tert-butyloxycarbonyl group; a (trimethylsilyl)ethyloxycarbonyl group; or R 4b\u2032  and R 4b\u2033  together with the bridging nitrogen form a group selected from: a group selected from: wherein R 4c  is a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl; a phenyl group; a benzyl group; or a tert-butyloxycarbonyl group.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 98.0
- Lexical Diversity: 1.88235
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14820711', '12680353', '12485108', '13910349', '11828457']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7928582946735628
- 35 USC 102 Novelty (BERT): 0.5392523734504336
- Combined Prediction Score: 0.7674977025512499
- Mean Citation Score: 342.51614000000006
- Max Citation Score: 362.67856
- Similarity Product: 256.9724911899471

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test