PATENT CLAIM ANALYSIS

Application Number: 15970128
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "235800"]

Abstract:
The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.

Claim (Index 6):
The pharmaceutical composition according to  claim 1 , wherein the HBV capsid assembly inhibitor is a compound of formula (III): wherein R 9  is hydrogen, halogen or C 1-6 alkyl; R 10  is hydrogen or halogen; R 11  is hydrogen or halogen; R 12  is C 1-6 alkyl; R 13  is hydrogen, hydroxyC 1-6 alkyl, aminocarbonyl, C 1-6 alkoxycarbonyl or carboxy; R 14  is hydrogen, C 1-6  alkoxycarbonyl or carboxy-C m H 2m -; X is carbonyl or sulfonyl; Y is \u2014CH 2 \u2014, \u2014O\u2014 or \u2014N(R 15 )\u2014,\n wherein R 15  is hydrogen, C 1-6 alkyl, haloC 1-6 alkyl, C 3-7 cycloalkyl-C m H 2m -, C 1-6 alkoxycarbonyl-C m H 2m -, \u2014C t H 2t \u2014COOH, -haloC 1-6 alkyl-COOH, -(C 1-6 alkoxy)C 1-6 alkyl-COOH, -C 1-6 alkyl-O-C 1-6 alkyl-COOH, -C 3-7 cycloalkyl-C m H 2m -COOH, -C m H 2m -C 3-7 cycloalkyl-COOH, hydroxy-C t H 2t , carboxyspiro[3.3]heptyl or carboxyphenyl-C m H 2m -, carboxypyridinyl-C m H 2m -; \n W is \u2014CH 2 \u2014, \u2014C(C 1-6 alkyl) 2 \u2014, \u2014O\u2014 or carbonyl; n is 0 or 1; m is 0-7; t is 1-7;\n or pharmaceutically acceptable salt, or enantiomer or diastereomer thereof.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 93.0
- Lexical Diversity: 1.38889
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14640397', '14946595', '14279716', '14991786', '14839376']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8140179498268888
- 35 USC 102 Novelty (BERT): 0.6547337107332093
- Combined Prediction Score: 0.7980895259175209
- Mean Citation Score: 514.621874
- Max Citation Score: 716.02423
- Similarity Product: 570.0744478201199

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test