PATENT CLAIM ANALYSIS

Application Number: 15873400
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["424", "489000"]

Abstract:
The present invention provides compositions, systems, and methods employing cleavable polymeric micelles. For example, provided herein are compositions comprising micelles that contain a hydrophobic agent (e.g., metal nanoparticles and/or therapeutic agent), where the micelles are formed from a plurality of amphiphilic polymer molecules that comprise a hydrophilic polymer and a hydrophobic polymer, where the hydrophobic polymer comprises a cleavable Furan-Maleimide adduct. Also provided herein are methods of administering such compositions to a subject and treating a localized area of the subject with a device that emits heat, NIR light, and/or alternating magnetic current such that at least some of the micelles inside the subject near the localized area are disrupted (e.g., releasing a therapeutic agent).

Claim (Index 5):
The method of  claim 1 , wherein said hydrophilic polymer is selected from the group consisting of: polyalkylene oxides, polyols, poly(oxyalkylene)-substituted diols and polyols, polyoxyethylated sorbitol, polyoxyethylated glucose, poly(acrylic acids) and analogs and copolymers thereof, polymaleic acids, polyacrylamides, poly(olefinic alcohols), polyethylene oxides, poly(N-vinyl lactams), polyoxazolines; polyvinylamines, and copolymers thereof.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 86.0
- Lexical Diversity: 1.87143
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15054739', '13697149', '12416993', '15048098', '12307356']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7378579929831637
- 35 USC 102 Novelty (BERT): 0.4996036661142338
- Combined Prediction Score: 0.7140325602962707
- Mean Citation Score: 255.5612
- Max Citation Score: 267.4456
- Similarity Product: 228.8395268269539

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test