PATENT CLAIM ANALYSIS

Application Number: 15985658
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-05
Patent Classification: ["424", "093200"]

Abstract:
The invention relates to the production of phage and transduction particles using DNAs (eg, plasmids and helper phage, mobile genetic elements (MGEs) or plasmids with chromosomally integrated helper phage genes), as well as the phage, helper phage, kits, compositions and methods involving these.

Claim (Index 120):
An antibacterial composition comprising a plurality of non self-replicative transduction particles comprising a nucleic acid encoding an antibacterial agent or component thereof, wherein the antibacterial agent is toxic to target bacterial cells, wherein the particles are capable of transducing into the target bacterial cells the nucleic acid encoding the antibacterial agent or component thereof for expression of the antibacterial agent or component in the target bacterial cells;\n wherein\n a) the antibacterial agent comprises a guided nuclease system; \n b) the particles comprise one, more or all of the tail proteins, portal protein and tail fiber proteins of a first phage and capsid proteins of the first phage; \n c) the nucleic acid comprises an origin of replication (ori) operable in a bacterial host cell for replication of the nucleic acid encoding the antibacterial agent or component thereof, wherein the first phage is capable of infecting cells of the same species or strain as the bacterial host cell; \n d) the nucleic acid comprises a packaging signal comprising a pac, cos or a homologue thereof that is operable with the first phage to package the nucleic acid in non self-replicative transduction particles; \n e) the particles are devoid of all phage terminase genes; and \n f) the particles are devoid of all phage structural protein genes.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 93.0
- Lexical Diversity: 1.5
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15460962', '15160405', '15817142', '15817135', '15817125']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7708533547272062
- 35 USC 102 Novelty (BERT): 0.5182469294682746
- Combined Prediction Score: 0.7455927122013131
- Mean Citation Score: 301.93261199999995
- Max Citation Score: 314.4234
- Similarity Product: 215.9906708501816

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test