PATENT CLAIM ANALYSIS

Application Number: 15937053
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["424", "400000"]

Abstract:
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing, arresting or reversing structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or peri-articular tissues caused by osteoarthritis or rheumatoid arthritis. Corticosteroid microparticle formulations are administered locally as a sustained release dosage form (with or without an immediate release component) that results in efficacy accompanied by clinically insignificant or no measurable effect on endogenous cortisol production.

Claim (Index 26):
An injectable formulation comprising controlled- or sustained-release microparticles comprising a Class B corticosteroid and a poly(lactic-co-glycolic) acid copolymer (PLGA) matrix, wherein the Class B corticosteroid is budesonide or a pharmaceutically-acceptable salt thereof, wherein the budesonide comprises between 22% to 28% of the microparticles and wherein the PLGA has the following characteristics: (i) a molecular weight in the range of about 40 to 70 kDa; and (ii) a lactide:glycolide molar ratio of 80:20 to 60:40, wherein the budesonide or pharmaceutically acceptable salt thereof is released for between 14 days and 90 days.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 90.0
- Lexical Diversity: 1.49206
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15459961', '14461884', '14461883', '13422994', '11607382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8356172609326152
- 35 USC 102 Novelty (BERT): 0.6961735047079035
- Combined Prediction Score: 0.821672885310144
- Mean Citation Score: 670.9881240000002
- Max Citation Score: 792.3644400000003
- Similarity Product: 712.4837317626072

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test