PATENT CLAIM ANALYSIS

Application Number: 16082753
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-02
Patent Classification: ["514", "386000"]

Abstract:
A compound of Formula I: or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of indoleamine 2,3-dioxygenase. The invention also relates to the use of the compounds of Formula (I) for the treatment or prevention of diseases cancer, infections, central nervous system disease or disorder, and immune-related disorders, either as a single agent or in combination with other therapies.

Claim (Index 1):
A compound of Formula I: or a pharmaceutically acceptable salt thereof wherein,\n R 1  is selected from the group consisting of: \n R 11  is H, halogen, (1-2C)alkyl or (1-2C)alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 12  is halogen, (1-2C)alkyl (2-3C)alkenyl, (2-3C)alkynyl, (1-2C)alkoxy, (3-8C)cycloalkyl, cyano or nitro all alkyl, alkoxy and cycloalkyl groups optionally being substituted with one or more halogen; R 13  is H, halogen, (1-2C)alkyl or (1-2C)alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 14  is H, halogen, (1-2C)alkyl or (1-2C)alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 15  is H, halogen, (1-2C)alkyl or (1-2C)alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 2  is selected from the group consisting of:\n a) hydrogen, \n b) (1-6C)alkyl, \n wherein (1-6C)alkyl optionally can be substituted, R 3  is selected from the group consisting of:\n a) (6-10C)aryl, \n b) (1-9C)heteroaryl, \n c) (3-8C)cycloalkyl, \n d) (2-7C)heterocycloalkyl, \n e) (1-6C)alkyl, \n f) (1-6)alkylamino, \n g) (3-6C)cycloalkylamino \n h) (6-10C)arylamino, \n i) (1-9C)heteroarylamino, \n j) (2-7C)heterocycloalkylamino, \n wherein all groups optionally can be substituted, R 4  is selected from the group consisting of:\n a) hydrogen, \n b) (1-6C)alkyl, \n wherein (1-6C)alkyl optionally can be substituted, R 5  is selected from the group consisting of:\n a) hydrogen, \n b) (1-6C)alkyl, \n wherein (1-6C)alkyl optionally can be substituted, A is selected from CH(R a ), C(O), S(O) or SO 2 , R a  is selected from the group consisting of:\n a) hydrogen, \n b) (1-6C)alkyl, \n wherein (1-6C)alkyl optionally can be substituted with fluorine or hydroxyl.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 97.0
- Lexical Diversity: 1.62264
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15128874', '12265091', '16317245', '13393767', '15748557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8305488282299421
- 35 USC 102 Novelty (BERT): 0.5445674824298984
- Combined Prediction Score: 0.8019506936499378
- Mean Citation Score: 347.380348
- Max Citation Score: 396.0309
- Similarity Product: 387.9019021320103

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test