PATENT CLAIM ANALYSIS

Application Number: 16254163
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["424", "001890"]

Abstract:
A method for detecting or ruling out renal amyloidosis in a subject is disclosed. The use of a stilbene derivative, such as florbetapir  18 F, or a phenylbenzothiazole derivative in positron emission tomography imaging, or integrated positron emission tomography/computed tomography imaging, can serve as a screening test for renal amyloidosis in a subject.

Claim (Index 17):
A method for detecting or ruling out renal amyloidosis in a subject, the method comprising:\n (a) administering to a subject a detectable amount of a compound of formula (V): wherein R 1 , R 2  and R 3  are independently selected from H, OH, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted amino, and substituted or unsubstituted carboxylate, wherein at least one of the atoms in R 1  or R 2  or R 3  is replaced with  3 H,  11 C,  13 C,  14 C,  13 N,  15 O,  75 Br,  76 Br,  18 F,  19 F,  68 G,  82 Rb,  111 In,  123 I,  125 I,  131 I,  201 TI, and  99m Tc, and wherein the compound is targeted to a kidney of the subject; and (b) acquiring an image to detect the presence or absence of any amyloidosis in a kidney of the subject.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.59459
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13878689', '15030214', '12064146', '15320112', '15748556']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7014665658600185
- 35 USC 102 Novelty (BERT): 0.5117188784204647
- Combined Prediction Score: 0.6824917971160632
- Mean Citation Score: 224.64024
- Max Citation Score: 262.05453
- Similarity Product: 162.7604307421875

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test