PATENT CLAIM ANALYSIS

Application Number: 15756908
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["435", "006100"]

Abstract:
The invention relates to the use of certain micro-RNAs circulating in the blood serum or blood plasma in the form of diagnostic profiles as a marker in an in vitro method for distinguishing between patients for which a myocardial biopsy is necessary for the diagnostic identification of a heart muscle disease and patients for which myocardial biopsy is not necessary, and for the optional differential diagnosis of individual non-ischemic cardiomyopathies or storage diseases affecting the heart.

Claim (Index 12):
The in-vitro or in-vivo method as claimed in  claim 1 , wherein the following steps performed:\n providing a sample obtained from a patient suspected of suffering from non-ischemic cardiomyopathy or a storage disease of the heart, bringing the sample into contact with at least two probes each comprising a sequence corresponding to the sequences of the microRNAs from at least one of the groups as set forth in any of  claims 1  to  0  or complementary to these, under conditions allowing hybridization between microRNAs contained in the sample and the probes, determining hybridization between microRNAs of the sample and the at least one probe and confirming the presence of a microRNA in the sample using the hybridization result of the previous step.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 90.0
- Lexical Diversity: 1.56
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13899555', '14788843', '15320208', '13642321', '15237364']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6391089589729052
- 35 USC 102 Novelty (BERT): 0.5216545543832932
- Combined Prediction Score: 0.627363518513944
- Mean Citation Score: 338.831186
- Max Citation Score: 342.94568
- Similarity Product: 245.86045315016744

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test