PATENT CLAIM ANALYSIS

Application Number: 15771043
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-02
Patent Classification: ["514", "021300"]

Abstract:
The present invention includes methods of improving proteolytic stability of a polypeptide, comprising alkylating at least one selected from the group consisting of a N-terminus amino group, the NH group of the N-terminus first internal amide bond, another primary amino group, a thiol group and a thioether group within the polypeptide. The present invention further includes polypeptides incorporating such chemical modifications.

Claim (Index 2):
The chemically modified polypeptide of  claim 1 , wherein the proteolysis is catalyzed by at least one selected from the group consisting of Acyl Peptide Hydrolase, DPP4, DPP2, DPP8, DPP9, Fibroblast Activation Protein (FAP), an S9B family oligopropyl peptidase and a protease with \u226550% homology to DPP4 and/or DPP2.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 91.0
- Lexical Diversity: 1.59524
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12845455', '13130962', '14182706', '13697021', '12066324']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7932725368426231
- 35 USC 102 Novelty (BERT): 0.5108107911188499
- Combined Prediction Score: 0.7650263622702458
- Mean Citation Score: 258.376928
- Max Citation Score: 264.86304
- Similarity Product: 167.83111385398863

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test