PATENT CLAIM ANALYSIS

Application Number: 15994074
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "186100"]

Abstract:
Methods of producing a pathogen with reduced replicative fitness are disclosed, as are attenuated pathogens produced using the methods. In particular examples, the method includes deoptimizing one or more codons in a coding sequence, thereby reducing the replicative fitness of the pathogen. Methods of using the attenuated pathogens as immunogenic compositions are also disclosed.

Claim (Index 9):
The modified virus of  claim 1 , wherein the viral nucleic acid comprises replacement of at least 50-2000 codons with synonymous codons less frequently used in the virus.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 93.0
- Lexical Diversity: 1.57895
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11576941', '12594173', '14766620', '15315687', '15508695']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7049051972235773
- 35 USC 102 Novelty (BERT): 0.7266187589751743
- Combined Prediction Score: 0.7070765533987369
- Mean Citation Score: 435.261758
- Max Citation Score: 906.7351
- Similarity Product: 757.9680357289076

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test