PATENT CLAIM ANALYSIS

Application Number: 15952616
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["546", "138000"]

Abstract:
Disclosed herein are compounds of Formula I wherein R 1 , R 2 , X, and Y are defined herein. These compounds are type II topoisomerase inhibitors and can be used in methods for treating infections caused by gram-positive pathogens, gram-negative pathogens, and drug-resistant strains thereof.

Claim (Index 31):
A method of treating a bacterial infection in a subject, the method comprising administering to a subject in need thereof an effective amount of a compound having the formula: or a pharmaceutically acceptable salt thereof, wherein:\n X is hydrogen, halogen, C 1-8  alkyl, C 1-8  alkoxy, or \u2014N(R X ) 2 , wherein each Rx is independently hydrogen, C 1-8  alkyl, or C 1-8  haloalkyl; \n Y is pyridyl optionally substituted with one group which is \u2014N(R Y1 ) 2  or \u2014C 1-8  alkyl-N(R Y1 ) 2 , and optionally substituted by one to two groups that are each independently halogen, C 1-8  alkyl, \u2014R Y , or C 1-8  alkyl-R Y ; \n R Y  is nitro, cyano, \u2014OR Y1 , \u2014SR Y1 , \u2014N(R Y1 ) 2 , \u2014C(O)R Y1 , \u2014C(O)OR Y1 , \u2014C(O)N(R Y1 ) 2 , \u2014OC(O)R Y1 , \u2014OC(O)OR Y1 , \u2014OC(O)N(R Y1 ) 2 , \u2014N(R Y1 )C(O)R Y1 , \u2014N(R Y1 )C(O)OR Y1 , \u2014N(R Y1 )C(O)N(R Y1 ) 2 , \u2014S(O) 2 R Y1 , \u2014S(O) 2 OR Y1 , \u2014S(O) 2 N(R Y1 ) 2 , \u2014OS(O) 2 R Y1 , \u2014OS(O) 2 OR Y1 , \u2014OS(O) 2 N(R Y1 ) 2 , \u2014N(R Y1 )S(O) 2 R Y1 , \u2014N(R Y1 )S(O) 2 R Y1 , or \u2014N(R Y1 )S(O) 2 N(R Y1 ) 2 ; and \n R Y1  is independently hydrogen, C 1-8  alkyl, or C 1-8  haloalkyl; \n wherein if X is hydrogen, then Y is pyridyl optionally substituted with one group which is \u2014N(R Y1 ) 2  or \u2014C 1-8  alkyl-N(R Y1 ) 2 , and substituted by one to two groups that are each independently halogen, C 1-8  alkyl, or C 1-8  alkyl-R Y .

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 1.34211
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15191067', '13821250', '12246778', '15500870', '10767638']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8107635423830252
- 35 USC 102 Novelty (BERT): 0.5427629160573444
- Combined Prediction Score: 0.7839634797504571
- Mean Citation Score: 375.741072
- Max Citation Score: 416.85693
- Similarity Product: 308.76635314666805

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test