PATENT CLAIM ANALYSIS

Application Number: 16020457
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "635000"]

Abstract:
Provided herein are methods for treating subjects having conditions related to adrenocortical activity and/or excessive steroid production. In particular, provided herein are methods for treating subjects having conditions related to adrenocortical activity and/or excessive steroid production through administration of at least one of the following agents: 1) an agent capable of inhibiting cholesterol efflux related to ABCA1 and/or ABCG1; 2) an agent capable of inhibiting MDR1 related cortisol secretion and/or MDR1 P-glycoprotein multiple drug transporter activity; and 3) an agent capable of inhibiting mitochondrial activity.

Claim (Index 4):
The method of  claim 1 , wherein the condition related to adrenocortical activity and/or excessive steroid production is selected from aldosteronism, primary aldosteronism, secondary aldosteronism, hyperaldosteronism, primary hyperaldosteronism, secondary hyperaldosteronism, adrenal insufficiency, Addison's Disease, adrenoleukodystrophy, pheochromocytoma, Cushing's Syndrome, adrenal hyperplasia, congenital adrenal hyperplasia, cancer, adrenal cancer, hypertension, primary hypertension, secondary hypertension, virilization, congenital syndromes leading to excessive corticosteroid production, Conns or other syndromes of excessive steroid production, and adrenocortical cancer (ACC).

Metadata:
- Claim Count in Document: 33.0
- Percentile: 94.0
- Lexical Diversity: 1.74074
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13802047', '15170682', '14798237', '14894281', '14148241']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7865903802832673
- 35 USC 102 Novelty (BERT): 0.5216027870497838
- Combined Prediction Score: 0.760091620959919
- Mean Citation Score: 276.233942
- Max Citation Score: 313.12173
- Similarity Product: 215.3182027554005

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test