PATENT CLAIM ANALYSIS

Application Number: 15757415
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-04
Patent Classification: ["435", "029000"]

Abstract:
There is described an isolated 3-dimensional liver spheroid wherein said spheroid has: increased ATP content as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; the same or increased activity of cytochrome P450 1A1 and cytochrome P450 1B1 as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; and increased albumin secretion as compared to a 3-dimensional liver spheroid cultured in William's E medium alone.

Claim (Index 4):
The isolated 3-dimensional liver spheroid according to  claim 1  or  claim 3 , wherein the spheroid is cultured in a cell culture medium comprising or consisting or consisting essentially of either: (a) Complete PneumaCult-ALI medium; or (b) Complete B-ALI medium; (c) Complete PneumaCult-ALI medium and Complete William's E medium, or (d) Complete B-ALI medium and Complete William's E medium.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 90.0
- Lexical Diversity: 1.95122
- Patent Class: 435.0
- Transitional Phrase Type: half
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12520008', '15134498', '12542505', '13882429', '12177017']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6159466408857565
- 35 USC 102 Novelty (BERT): 0.5066387308509831
- Combined Prediction Score: 0.6050158498822792
- Mean Citation Score: 224.67701
- Max Citation Score: 240.10646
- Similarity Product: 151.6412560949516

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test