PATENT CLAIM ANALYSIS

Application Number: 15896811
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "006100"]

Abstract:
Hence, the invention relates to a method for diagnosis and/or prognosis of cancer, comprising the steps of analyzing in a sample of a subject the DNA methylation status of a genomic region of at least one member of the group of, (i) SFN according to SEQ ID NO. 1, (ii) SLIT2 according to SEQ ID NO. 2, (iii) SERPINB5 according to SEQ ID NO. 3; and (iv) TWIST 1 according to SEQ ID NO 4; wherein, if (i) SFN shows a methylation cut-off value of above 80% and/or, (ii) SLIT2 shows a methylation cut-off value of above 45% and/or, (iii) SERPBINB5 shows a methylation cut-off value of above 70%, and/or (iv) TWIST 1 shows a methylation level below 15% the sample is categorized as a sample from a patient with cancer and/of a poor prognosis.

Claim (Index 23):
The detectably labeled nucleic acid of  claim 21 , wherein the probe comprises one or more modified nucleic acids.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 2.32877
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14386292', '10517741', '10582705', '15079948', '12520841']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6531764515265702
- 35 USC 102 Novelty (BERT): 0.5523314232389996
- Combined Prediction Score: 0.6430919486978132
- Mean Citation Score: 334.599082
- Max Citation Score: 449.0426
- Similarity Product: 307.60892959918976

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test