PATENT CLAIM ANALYSIS

Application Number: 16015028
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "006100"]

Abstract:
In various embodiments a molecular circuit is disclosed. The circuit comprises a negative electrode, a positive electrode spaced apart from the negative electrode, and an enzyme molecule conductively attached to both the positive and negative electrodes to form a circuit having a conduction pathway through the enzyme. In various examples, the enzyme is a polymerase. The circuit may further comprise molecular arms used to wire the enzyme to the electrodes. In various embodiments, the circuit functions as a sensor, wherein electrical signals, such as changes to voltage, current, impedance, conductance, or resistance in the circuit, are measured as substrates interact with the enzyme.

Claim (Index 14):
The circuit of  claim 1 , wherein at least one of the first end of the arm molecule or the second electrode connects to the enzyme at connection points in the enzyme comprising at least one of a native cysteine, a genetically engineered cysteine, a genetically engineered amino acid with a conjugation residue, or a genetically engineered peptide domain comprising a peptide that has a conjugation partner.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 94.0
- Lexical Diversity: 1.95082
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16015049', '15366849', '15336557', '14317411', '15227661']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5845141027467384
- 35 USC 102 Novelty (BERT): 0.5203244140641092
- Combined Prediction Score: 0.5780951338784756
- Mean Citation Score: 221.65214
- Max Citation Score: 326.36655
- Similarity Product: 272.55230311566004

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test