PATENT CLAIM ANALYSIS

Application Number: 16162335
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["424", "422000"]

Abstract:
Disclosed herein are methods and pharmaceutical compositions for sustained release of anticancer agents. Such pharmaceutical compositions may provide a burst-free, sustained release of one or more anticancer agents and may include a plurality of poly(lactic-co-glycolic) acid (PLGA) microparticles encapsulating the one or more anticancer agents.

Claim (Index 30):
A pharmaceutical composition comprising a population of small microparticles and a population of large microparticles,\n wherein the small microparticles and the large microparticles are comprised of poly(lactic-co-glycolic) acid (PLGA) polymer units; wherein the large microparticles encapsulate an anticancer agent and have a mean particle diameter of about 10 to about 100 micrometers, and wherein the PLGA polymer units of the large microparticles have a molecular weight of about 17 kDa to about 25 kDa; wherein the small microparticles encapsulate an immunosuppressive agent or an anti-inflammatory agent and have a mean particle diameter of about 0.5 to about 10 micrometers, and wherein the PLGA polymer units of the small microparticles have a molecular weight of about 5 kDa to about 15 kDa; and wherein the small microparticles and the large microparticles comprise PLGA at a ratio of poly-lactide to poly-glycolide of 30:70 to 70:30 by weight.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 97.0
- Lexical Diversity: 1.55882
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12664792', '11607382', '13422994', '14461884', '15349985']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7325386004980298
- 35 USC 102 Novelty (BERT): 0.5026980744571504
- Combined Prediction Score: 0.7095545478939419
- Mean Citation Score: 239.511742
- Max Citation Score: 251.67445
- Similarity Product: 171.82216182558838

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test