PATENT CLAIM ANALYSIS

Application Number: 15953494
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "235800"]

Abstract:
Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Claim (Index 30):
The compound of  claim 26 , or a pharmaceutically acceptable salt thereof, wherein G is N, R 1  is methyl, Z is O, R 3  and R 4  are independently hydrogen or halogen, and R6 is \u2014OR 3a , \u2014OCH 2 R 3b , or \u2014OCH(CH 3 )R 3b ; wherein\n R 3a  and R 3b  are independently hydrogen, phenyl, naphthyl, pyridyl, pyrimidinyl, imidazolyl, 1,2,3-triazolyl, quinolinyl, isoquinolinyl, thiazolyl, tetrazolyl groups, C 1-6 alkyl, cyclic \u2014(C 1-8 alkyl)-, cyclic \u2014(C 1-8 oxaalkyl)-, cyclic \u2014(C 1-4 azaalkyl)-, C 2-6 alkenyl, C 2-6 alkynyl;\n wherein the phenyl, naphthyl, pyridyl, pyrimidinyl, imidazolyl, 1,2,3-triazolyl, quinolinyl, isoquinolinyl, thiazolyl, or tetrazolyl groups are optionally substituted with 1-3 substituents independently selected from the group consisting of halogen, thiol, C 1-6 alkyl thioether, C 1-6 alkyl sulfoxide, C 1-6 alkyl, C 1-6 alkoxyl, amino, C 1-6 alkylamino, C 1-6 alkylamino, C 1-6 alkyl sulfonamide, azido, \u2014CHO, \u2014CO 2 H, C 1-6 alkyl carboxylate, cyano, C 2-6 alkeny, and C 2-6 alkynyl group; and the C 1-6 alkyl, cyclic \u2014(C 1-8 alkyl)-, cyclic \u2014(C 1-6 oxaalkyl)-, cyclic \u2014(C 1-6 azaalkyl)-, C 2-6 alkenyl, or C 2-6 alkynyl groups are selectively functionalized with one or more halogen, thiol, hydroxyl, carbonyl, carboxyl, carbonyloxyl, C 1-6 alkoxy, C 1-6 hydroxyalkoxy, amino, C 1-6 alkylamino, di(C 1-6 alkyl)amino, azido, piperidinyl, phenyl, naphthyl, pyridyl, pyrimidinyl, imidazolyl, 1,2,3-triazolyl, quinolinyl, isoquinolinyl, thiazolyl, or tetrazolyl groups.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 91.0
- Lexical Diversity: 1.33333
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15953492', '12096432', '14343410', '12312749', '15522969']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7903276453284033
- 35 USC 102 Novelty (BERT): 0.5583412131770024
- Combined Prediction Score: 0.7671290021132632
- Mean Citation Score: 329.689702
- Max Citation Score: 430.0401
- Similarity Product: 323.6918373265028

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test