PATENT CLAIM ANALYSIS

Application Number: 15917549
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["435", "006110"]

Abstract:
The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Claim (Index 12):
The system of  claim 1 , wherein the one or more guide RNAs comprise a mismatch.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.38889
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15917546', '15467922', '15916271', '14975085', '15897089']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.695142698569243
- 35 USC 102 Novelty (BERT): 0.5929057322986944
- Combined Prediction Score: 0.6849190019421881
- Mean Citation Score: 415.336298
- Max Citation Score: 717.7631
- Similarity Product: 413.1085235923886

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test