PATENT CLAIM ANALYSIS

Application Number: 16297354
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["514", "04400A"]

Abstract:
This invention relates to compounds, compositions, and methods useful for reducing Glycolate Oxidase (HAO1) target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.

Claim (Index 94):
A nucleic acid comprising an oligonucleotide strand of 21-23 nucleotides in length, wherein the oligonucleotide is sufficiently complementary to a target region of HAO1 mRNA having a sequence as set forth in SEQ ID NO: [[1832]]1823 along at least 15 nucleotides of the oligonucleotide strand length to reduce HAO1 target mRNA expression when the nucleic acid is introduced into a cell expressing the HAO1 mRNA.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 99.0
- Lexical Diversity: 1.1875
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15793441', '14583200', '15616254', '16297316', '16168671']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.906365940218697
- 35 USC 102 Novelty (BERT): 0.7423604691805488
- Combined Prediction Score: 0.8899653931148822
- Mean Citation Score: 910.7023319999996
- Max Citation Score: 971.7144
- Similarity Product: 833.9655648224831

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test