PATENT CLAIM ANALYSIS

Application Number: 15891585
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "248000"]

Abstract:
This invention is directed to compounds of formula (I): where r, q, R, R 2 , R 3 , R 4 , R 5a , R 5b , R 5c , R 6a , R 6b , R 6c , R 7 , R 8 , and R 9  are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A 4  hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

Claim (Index 17):
The method according to  claim 16  wherein:\n r is 0; \n R 4  is a direct bond, \u2014O\u2014R 12a \u2014, or an optionally substituted straight or branched methylene, ethylene or propylene chain; \n R 5a , R 5b , R 5c , R 6a , R 6b  and R 6c  are each independently selected from hydrogen, alkyl, haloalkyl or hydroxyalkyl; \n R 8  is benzyl substituted with one or more substituents selected from \u2014R 13 \u2014OR 10  and \u2014R 13 \u2014C(\u2550O)OR 10 ; \n R 10  is hydrogen, alkyl or optionally substituted aryl; \n R 12  is CM alkylene, optionally substituted with one or more substituents selected from the group consisting of \u2014OR 10 ; and \n R 12a  is methylene, ethylene or propylene, optionally substituted with one or more substituents selected from the group consisting of \u2014OR 10 .

Metadata:
- Claim Count in Document: 76.0
- Percentile: 88.0
- Lexical Diversity: 1.75714
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14313672', '11644244', '14849810', '12771659', '15840097']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7995814374217002
- 35 USC 102 Novelty (BERT): 0.5935377349064872
- Combined Prediction Score: 0.7789770671701789
- Mean Citation Score: 393.50533800000005
- Max Citation Score: 528.1824
- Similarity Product: 424.1783688892365

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test