PATENT CLAIM ANALYSIS

Application Number: 16501284
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["514", "252100"]

Abstract:
The present invention relates to trifluoroacetyl hydrazide compounds and medical uses thereof. The compounds have a structure of the following formula: The compounds showed multifunctional mechanisms, including inhibition of glutamate excitotoxicity, activation of MEF2 transcriptional activity, clearance of free radicals, and promotion of nerve differentiation, and has a better protective effect on cells especially nerve cells. The compound can be used to prepare prophylactic or therapeutic medicaments with cytoprotective effects, for the prevention or treatment of diseases related to glutamate receptor activation, MEF2 disorders or excessive free radicals generation. The diseases include, for example, neurodegenerative diseases such as Alzheimer's disease, Parkinson and stroke, and the free radicals related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.

Claim (Index 2):
The method of  claim 1 , wherein the alkyl group is a lower alkyl group.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 1.67857
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15731538', '13254653', '14999766', '15441998', '14086815']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7191811557760653
- 35 USC 102 Novelty (BERT): 0.5768141552879976
- Combined Prediction Score: 0.7049444557272586
- Mean Citation Score: 236.45833
- Max Citation Score: 442.09186
- Similarity Product: 415.8841107782197

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test