PATENT CLAIM ANALYSIS

Application Number: 15764283
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "532000"]

Abstract:
The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).

Claim (Index 9):
The compound according to  claim 1 , which is selected from:\n 15,19-difluoro-8-[(S-methylsulfonodiimidoyl)methyl]-3,4-dihydro-2H, 11H-10,6-(azeno)-12,16-(metheno)-1,5,11,13-benzodioxadiazacyclooctadecine; (rac)-3-(2-{[15,19-difluoro-3,4-dihydro-2H,11H-10,6-(azeno)-12,16-(metheno)-1,5,11,13-benzodioxadiazacyclooctadecin-8-yl]methyl}-2-methyl-2\u03bb 6 -diazathia-1,2-dien-1-yl)propan-1-ol; (rac)-[{[15,19-difluoro-3,4-dihydro-2H, 11H-10,6-(azeno)-12,16-(metheno)-1,5,11,13-benzodioxadiazacyclooctadecin-8-yl]methyl}(imino)methyl-) 6 -sulfanylidene]cyanamide; (rac)-8-[(N,S-dimethylsulfonodiimidoyl)methyl]-15,19-difluoro-3,4-dihydro-2H, 11H-10,6-(azeno)-12,16-(metheno)-1,5,11,13-benzodioxadiazacyclooctadecine, and 16,20-difluoro-9-[(S-methylsulfonodiimidoyl)methyl]-2,3,4,5-tetrahydro-12H-13,17-(azeno)-11,7-(metheno)-1,6,12,14-benzodioxadiazacyclononadecine; 16,20,21-trifluoro-9-[(S-methylsulfonodiimidoyl)methyl]-2,3,4,5-tetrahydro-12H-13,17-(azeno)-11,7-(metheno)-1,6,12,14-benzodioxadiazacyclononadecine; 16,21-difluoro-9-[(S-methylsulfonodiimidoyl)methyl]-2,3,4,5-tetrahydro-12H-13,17-(azeno)-11,7-(metheno)-1,6,12,14-benzodioxadiazacyclononadecine; 15,19-difluoro-8-[(S-methylsulfonodiimidoyl)methyl]-3,4-dihydro-2H, 11H-10,6-(azeno)-12,16-(metheno)-1,5,11,13-benzodioxadiazacyclooctadecine-7-carbonitrile; (rac)-9-[(N-cyclopropyl-S-methylsulfonodiimidoyl)methyl]-16,20-difluoro-2,3,4,5-tetrahydro-12H-13,17-(azeno)-11,7-(metheno)-1,6,12,14-benzodioxadiazacyclononadecine; (rac)-9-[(N,S-dimethylsulfonodiimidoyl)methyl]-16,20-difluoro-2,3,4,5-tetrahydro-12H-13,17-(azeno)-11,7-(metheno)-1,6,12,14-benzodioxadiazacyclononadecine; and an enantiomer, diastereomer, salt, solvate or salt of solvate thereof.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 90.0
- Lexical Diversity: 1.65909
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15303212', '15764289', '14345353', '14443368', '14443180']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8272605412685167
- 35 USC 102 Novelty (BERT): 0.6063172555930803
- Combined Prediction Score: 0.8051662127009731
- Mean Citation Score: 421.604676
- Max Citation Score: 531.68835
- Similarity Product: 500.3037710401298

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test