PATENT CLAIM ANALYSIS

Application Number: 16156833
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["607", "088000"]

Abstract:
Devices, systems, and methods for treating dementia or Alzheimer's disease in a subject in need thereof. In one example, chronic visual stimuli having a frequency of about 30 Hz to about 50 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to entrain gamma oscillations in multiple brain regions of the subject, including the prefrontal cortex (PFC) and the hippocampus. The entrained gamma oscillations modulate neuronal activity across multiple brain regions (e.g., facilitate functional binding of neural networks at low gamma frequencies) to induce various neuroprotective effects (e.g., amelioration of amyloid plaques and tau hyper-phosphorylation) and reduce neurodegeneration. Neuronal activity mediated by the chronic visual stimuli reduces an immune response in microglia and ameliorates aberrantly modified genes and proteins involved in membrane trafficking, intracellular transport, synaptic function, neuroinflammation and DNA damage response. Behavior modification including enhanced learning and memory is observed.

Claim (Index 20):
The method of  claim 16 , wherein A) comprises non-invasively delivering the chronic visual stimuli for at least I hour per day for greater than seven days.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.55556
- Patent Class: 607.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15647157', '15360637', '14138376', '13884980', '14115368']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6655763451876143
- 35 USC 102 Novelty (BERT): 0.5322628053569469
- Combined Prediction Score: 0.6522449912045476
- Mean Citation Score: 262.296608
- Max Citation Score: 397.97382000000016
- Similarity Product: 222.1845449183357

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test