PATENT CLAIM ANALYSIS

Application Number: 16259541
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["424", "423000"]

Abstract:
A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a compressed gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.

Claim (Index 1):
A method of forming a biomedical implant comprising a drug/polymer composite material, the method comprising the steps of:\n (a) combining a solid particulate macrolide immunosuppressive drug material in crystalline form having a therapeutic effect with a solid particulate polymer material, and optionally with a pharmaceutical excipient, to intersperse drug particles within polymer particles; (b) constraining the interspersed drug and polymer in a mold so that the drug particles and the polymer particles are immobilized; and then (c) permeating the mold with a compressed gas solvent to contact the interspersed drug and polymer particles at a pressure sufficient to reduce the viscosity of said polymer material such that said polymer particles are fused to one another around the drug particles to capture said drug particles therebetween without mobilization of the drug particles and to form a drug/polymer composite material from said particulate mixture, the compressed gas solvent being a densified gas or a near supercritical or supercritical fluid, wherein the biomedical implant comprising the polymer-drug composite is formed without physically or chemically changing the state of the drug during processing.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 99.0
- Lexical Diversity: 1.42308
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11078554', '10434435', '13942199', '10820091', '13194404']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6807903400290012
- 35 USC 102 Novelty (BERT): 0.4691647432913707
- Combined Prediction Score: 0.6596277803552382
- Mean Citation Score: 140.05798199999998
- Max Citation Score: 143.86266
- Similarity Product: 104.43747570599557

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test