PATENT CLAIM ANALYSIS

Application Number: 16045901
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["546", "310000"]

Abstract:
Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

Claim (Index 16):
The method of  claim 15 , wherein the pH of the Suzuki coupling reaction is from about 8 to about 10.

Metadata:
- Claim Count in Document: 60.0
- Percentile: 95.0
- Lexical Diversity: 1.47826
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16045896', '15599716', '14049664', '13356691', '11906972']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7731010630499711
- 35 USC 102 Novelty (BERT): 0.5662374315321849
- Combined Prediction Score: 0.7524146998981924
- Mean Citation Score: 318.482256
- Max Citation Score: 443.61133
- Similarity Product: 368.8098033471405

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test