PATENT CLAIM ANALYSIS

Application Number: 15900846
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "185100"]

Abstract:
An object is to provide an antibody capable of specifically recognizing a human NRG1 protein isoform, and suppressing signal transduction in which the isoform is involved. An antibody capable of binding to a region at positions 221 to 234 of a human NRG1-α protein or an antibody capable of binding to a region at positions 213 to 239 of a human NRG1-β1 protein was successfully obtained. Further, it was also found that these antibodies had an activity of suppressing cleavage of the NRG1 protein, an activity of suppressing phosphorylation of an ErbB3 protein in a cancer cell, and an activity of suppressing in vivo tumor proliferation.

Claim (Index 21):
A composition for treating or preventing a cancer, the composition comprising the antibody according to  claim 14  as an active ingredient and a pharmaceutically acceptable carrier or medium.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 1.98246
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14765581', '10130034', '13698420', '15141593', '14061548']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7005923274466418
- 35 USC 102 Novelty (BERT): 0.6222792468563956
- Combined Prediction Score: 0.6927610193876171
- Mean Citation Score: 379.510594
- Max Citation Score: 641.1614400000002
- Similarity Product: 483.86757401598953

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test