PATENT CLAIM ANALYSIS

Application Number: 15744312
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["504", "155000"]

Abstract:
The invention relates to substituted cyclic aryl- and heteroarylcarbonyl hydrazides of the general formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description for enhancing stress tolerance in plants to abiotic stress, and for enhancing plant growth and/or for increasing plant yield.

Claim (Index 3):
A substituted cyclic aryl- or heteroarylcarbonyl hydrazide or salt as claimed in  claim 1 , where\n R 1 , R 2  and R 38  are independently hydrogen, halogen, cyano, nitro, NR 39 R 40 , OR 41 , S(O) n R 42 , thiocyanato, isothiocyanato, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, pentafluorothio, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-haloalkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-haloalkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 4 -C 10 )-cycloalkenyl-(C 1 -C 6 )-alkyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylcarbonyl-(C 1 -C 6 )-alkyl, COOR 42 , CONR 39 R 40 , COR 41 ,\n \u2014\u2550NOR 41 , R 41 OOC\u2014(C 1 -C 6 )-alkyl, aryl-(C 1 -C 6 )-alkynyl, heteroaryl-(C 1 -C 6 )-alkynyl, heterocyclyl-(C 1 -C 6 )-alkynyl, tris[(C 1 -C 6 )-alkyl]silyl-(C 2 -C 6 )-alkynyl, bis[(C 1 -C 6 )-alkyl](aryl)silyl-(C 2 -C 6 )-alkynyl, bisaryl [(C 1 -C 6 )-alkyl]silyl-(C 2 -C 6 )-alkynyl, (C 3 -C 6 )-cycloalkyl-(C 2 -C 6 )-alkynyl, aryl-(C 2 -C 6 )-alkenyl, heteroaryl-(C 2 -C 6 )-alkenyl, heterocyclyl-(C 2 -C 6 )-alkenyl, (C 3 -C 6 )-cycloalkyl-(C 2 -C 6 )-alkenyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylaminosulfonylamino, (C 3 -C 6 )-cycloalkylaminosulfonylamino, diazo, aryldiazo, tris[(C 1 -C 6 )-alkyl]silyl, bis[(C 1 -C 6 )-alkyl](aryl)silyl, bisaryl[(C 1 -C 6 )-alkyl]silyl, \n X 1 , X 2 , X 3  and X 4  are the same or different and are independently N (nitrogen) or the C\u2014R 2  moiety, but there are never more than two adjacent nitrogen atoms, and where R 2  in each C\u2014R 2  moiety is the same or different as defined below, and where R 1  and R 2  are not both hydrogen when X 1 , X 2 , X 3  and X 4  are C\u2014R 2 , W is O (oxygen) or S (sulfur), A 1 , A 2 , A 3 , A 4  and A 5  are the same or different and are each independently N (nitrogen) or the C\u2014R 38  moiety, but there are never more than two adjacent nitrogen atoms, and where R 38  in each C\u2014R 38  moiety is the same or different as defined above, Q together with the CR 3 R 4  group and the nitrogen atom to which they are bonded forms a fully saturated, partly saturated or fully unsaturated 3-7-membered ring which is optionally interrupted by heteroatoms and optionally has further substitution, and is additionally the moieties Q-1 to Q-15 where R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 , R 25 , R 26 , R 27 , R 28 , R 29 , R 30 , R 31 , R 32 , R 33 , R 34 , R 35 , R 36  and R 37  are each defined according to the definitions above and where the arrow represents a bond to the nitrogen atom of the hydrazide group, R 3 , R 4 , R 17 , R 18 , R 19  and R 20  are independently hydrogen, halogen, NR 39 R 40 , S(O) n R 42 , cyano, nitro, cyano-(C 1 -C 6 )-alkyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, (C 1 -C 10 )-haloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-haloalkynyl, (C 2 -C 6 )-alkynyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-haloalkenyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylamino-(C 1 -C 6 )-alkyl, bis[(C 1 -C 6 )-alkyl]amino-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkylamino-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, COR 41 , COOR 41 , CONR 39 R 40 , hydroxycarbonyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyloxycarbonyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkynyloxycarbonyl-(C 1 -C 6 )-alkyl, aryl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylcarbonyl-(C 1 -C 6 )-alkyl, or together with the atom to which they are bonded form an oxo group, R 5  and R 6  are independently hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, COOR 41 , CONR 39 R 40 , hydroxycarbonyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyloxycarbonyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkynyloxycarbonyl-(C 1 -C 6 )-alkyl, aryl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, heteroaryl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, heterocyclyl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 21 , R 22 , R 23 , R 24 , R 25 , R 26 , R 27 , R 28 , R 30 , R 31 , R 32 , R 33 , R 34 , R 35  and R 36  are independently hydrogen, cyano, nitro, halogen, hydroxyl, (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy, (C 1 -C 6 )-alkylthio, (C 1 -C 6 )-haloalkoxy, (C 1 -C 6 )-haloalkylthio, (C 3 -C 10 )-cycloalkyl, (C 1 -C 10 )-haloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-haloalkynyl, (C 2 -C 6 )-alkynyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-haloalkenyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, COR 41 , COOR 41 , CONR 39 R 40 , R 37  is hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 3 -C 10 )-cycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 1 -C 10 )-haloalkyl, (C 1 -C 6 )-alkoxy, (C 2 -C 6 )-alkenyloxy, aryl, heteroaryl, heterocyclyl, COR 41 , COOR 41 , CONR 39 R 40 , S(O) n R 42 , n is 0, 1 or 2, R 39  and R 40  are the same or different and are independently hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 6 )-cyanoalkyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-haloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 4 -C 10 )-cycloalkenyl-(C 1 -C 6 )-alkyl, COR 41 , SO 2 R 42 , (C 1 -C 6 )-alkyl-HNO 2 S\u2014, (C 3 -C 6 )-cycloalkyl-HNO 2 S\u2014, heterocyclyl, (C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxycarbonyl, aryl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, aryl-(C 1 -C 6 )-alkoxycarbonyl, heteroaryl-(C 1 -C 6 )-alkoxycarbonyl, (C 2 -C 6 )-alkenyloxycarbonyl, (C 2 -C 6 )-alkynyloxycarbonyl, heterocyclyl-(C 1 -C 6 )-alkyl, R 41  is hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 6 )-cyanoalkyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-haloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 4 -C 10 )-cycloalkenyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyloxycarbonyl-(C 1 -C 6 )-alkyl, aryl-(C 1 -C 6 )-alkoxycarbonyl-(C 1 -C 6 )-alkyl, hydroxycarbonyl-(C 1 -C 6 )-alkyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl and R 42  is hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 6 )-cyanoalkyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, (C 3 -C 10 )-halocycloalkyl, (C 4 -C 10 )-cycloalkenyl, (C 4 -C 10 )-halocycloalkenyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-haloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, (C 4 -C 10 )-cycloalkenyl-(C 1 -C 6 )-alkyl, NR 39 R 40 . Y is a bond or the Y-1 to Y-7 moieties where R 43 , R 44 , R 45 , R 46 , R 47 , R 48 , R 49 , R 50 , R 51 , R 52 , R 53  and R 54  are each as per the definition below and where the arrow represents a bond to the 6-membered ring with the A 1 , A 2 , A 3 , A 4  and A 5  moieties, R 43 , R 44 , R 45 , R 46 , R 47 , R 48 , R 49 , R 50 , R 51 , R 52 , R 53  and R 54  are independently hydrogen, (C 1 -C 6 )-alkyl, (C 2 -C 6 )-alkenyl, (C 2 -C 6 )-alkynyl, (C 1 -C 10 )-haloalkyl, (C 2 -C 6 )-haloalkenyl, (C 2 -C 6 )-haloalkynyl, (C 3 -C 10 )-cycloalkyl, aryl, aryl-(C 1 -C 6 )-alkyl, heteroaryl, heteroaryl-(C 1 -C 6 )-alkyl, (C 3 -C 6 )-cycloalkyl-(C 1 -C 6 )-alkyl, heterocyclyl, heterocyclyl-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkylthio-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkoxy-(C 1 -C 6 )-alkyl, (C 1 -C 6 )-haloalkylthio-(C 1 -C 6 )-alkyl, COOR 23 , R 1  and X 1 , when X 1  is a C\u2014R 2  group, together with the atoms to which they are bonded form a fully saturated, partly saturated or fully unsaturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, X 1  and X 2 , when each is a C\u2014R 2  group, together with the atoms to which they are bonded form a fully saturated, partly saturated or fully unsaturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, A 1  and A 2 , when each is a C\u2014R 7  group, together with the atoms to which they are bonded form a fully saturated, partly saturated or fully unsaturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, A 2  and A 3 , when each is a C\u2014R 7  group, together with the atoms to which they are bonded form a fully saturated, partly saturated or fully unsaturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, A 3  and A 4 , when each is a C\u2014R 7  group, together with the atoms to which they are bonded form a fully saturated, partly saturated or fully unsaturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, R 3  and R 4  together with the atom to which they are bonded form a fully saturated or partly saturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, R 5  and R 6  together with the atom to which they are bonded form a fully saturated or partly saturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, R 3  and R 23  together with the atoms to which they are bonded form a fully saturated or partly saturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution, R 9  and R 10  together with the atom to which they are bonded form a fully saturated or partly saturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution and R 15  and R 16  together with the atom to which they are bonded form a fully saturated or partly saturated 5-7-membered ring optionally interrupted by heteroatoms and optionally having further substitution.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 86.0
- Lexical Diversity: 1.39024
- Patent Class: 504.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14767621', '15763385', '14772471', '15563414', '15533565']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.783336935641245
- 35 USC 102 Novelty (BERT): 0.5553153292306383
- Combined Prediction Score: 0.7605347750001843
- Mean Citation Score: 358.417324
- Max Citation Score: 369.07028
- Similarity Product: 296.2822292486215

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test