PATENT CLAIM ANALYSIS

Application Number: 15935739
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["424", "464000"]

Abstract:
The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.

Claim (Index 35):
The pharmaceutical composition of  claim 28 , wherein upon oral administration of a single dose of said composition comprising about 100 mg to about 8000 mg of DGLA to a fasted subject the subject exhibits one or more of the following outcomes:\n (a) a free DGLA Cmax of about 700 ng/ml to about 3200 ng/ml; (b) a free DGLA AUC0-24 of about 2500 ng\u00b7h/ml to about 10000 ng\u00b7h/ml; (c) a free DGLA AUC0-24/dose of about 2 to about 6 h/kL; (d) a free DGLA tmax (h) of about 3 to about 8 hours; (e) a total DGLA Cmax of about 7000 ng/ml to about 32000 ng/ml; (f) a total DGLA AUC0-24 of about 25,000 ng\u00b7h/ml to about 225,000 ng\u00b7h/ml; (g) a total DGLA AUC0-24/dose 70 to about 225 h/kL; (h) a total DGLA tmax (h) of about 3 to about 20 hours; (i) a total DGLA Cmax/dose of about 2 (1/kL) to about 25 (1/kl), about 4 (1/kl) to about 20 (1/kl) or about 5 (1/kl) to about 17 (1/kl); (j) a free DGLA Cmax/dose of about 0.3 (1/kL) to about 2.5 (1/kL) (k) a ratio of total DGLA Cmax to free DGLA Cmax of about 7:1 to about 9:1; and/or (l) a ratio of free DGLA plasma to DGLA skin as measured in skin blister fluid from about 0.6:1 to about 1.5:1.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 90.0
- Lexical Diversity: 1.13636
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14730818', '15661374', '14307195', '15898148', '15898143']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6974439792078003
- 35 USC 102 Novelty (BERT): 0.554532320325919
- Combined Prediction Score: 0.6831528133196122
- Mean Citation Score: 317.293044
- Max Citation Score: 448.53607
- Similarity Product: 314.27042294552564

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test