PATENT CLAIM ANALYSIS

Application Number: 15759575
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-06
Patent Classification: ["514", "262100"]

Abstract:
The present invention is related to the medical technology field. This invention discloses the application of sildenafil at low doses as an antitumor drug, with the chemical name of 1-[4-ethyl-3-[5-(6,7-Two-methyl-7-oxygen generation-3-propyl H pyrazole and [4,3d] pyrimidine)] phenyl sulfonyl-4-biphenyl methyl piperazine, and the use dosage is: the oral dosage of 0.04˜0.5 mg per 1 kg of body weight, or 2˜25 mg for an adult with body weight of 50 kg, or injection dosage of 0.04˜0.2 mg per 1 kg of body weight, or 2˜10 mg for an adult with body weight of 50 kg, or external dosage in a mass percentage of less than 1% of sildenafil. This invention is applicable to the treatment of malignant tumors. It inhibits tumor growth by more than 50% without significant toxic or side effects, and thereby, sildenafil can be used in control of tumor growth and for improvement of other treatments of tumor.

Claim (Index 4):
According to the application of sildenafil at low dosage as an anticancer agent mentioned in  claim 2 , with its characteristic that the oral dosage of sildenafil is 0.04\u02dc0.5 mg per 1 kg of body weight, or 2\u02dc25 mg for an adult with body weight of 50 kg.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 90.0
- Lexical Diversity: 1.83158
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11139730', '10590992', '12097157', '14281363', '14363245']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7634965235946498
- 35 USC 102 Novelty (BERT): 0.493805505183216
- Combined Prediction Score: 0.7365274217535064
- Mean Citation Score: 189.63525
- Max Citation Score: 193.95088
- Similarity Product: 129.90715174713137

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test