PATENT CLAIM ANALYSIS

Application Number: 15767966
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["564", "501000"]

Abstract:
The present invention relates to an industrial process for the preparation of (5S,10S)-10-benzyl-16-methyl-11,14,18-trioxo-15,17,19-trioxa-2,7,8-trithia-12-azahenicosan-5-aminium (E)-3-carboxyacrylate salt of following formula (I): wherein X is fumarate. This process comprises the following successive key steps: a kinetic resolution, formation of disulfide compound, peptide coupling, and anion exchange reaction to obtain the desired product of formula (I).

Claim (Index 9):
Industrial process, according to  claim 1 , wherein step 3 comprises the following steps:\n 3a) solubilizing compound F in polar and aprotic solvent, then 3b) to the reaction mixture obtained after step 3a adding 1.2 molar equivalents of O-Benzotriazol-1-yl-N,N,N\u2032,N\u2032-tetramethyluronium hexafluorophosphate and diisopropyl-ethyl-amine. 3c) to the reaction mixture obtained after step 3b adding 1.3 molar equivalents of aminoester C.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.40816
- Patent Class: 564.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13144391', '14001756', '13879258', '14367216', '15935558']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.713783951026914
- 35 USC 102 Novelty (BERT): 0.505586065988342
- Combined Prediction Score: 0.6929641625230568
- Mean Citation Score: 184.35517
- Max Citation Score: 192.49998
- Similarity Product: 139.1043145971894

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test