PATENT CLAIM ANALYSIS

Application Number: 15900211
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "133100"]

Abstract:
IVIG replacement compounds are derived from recombinant and/or biochemical creation of immunologically active biomimetic(s). These replacement compounds are then screened in vitro to assess each replacement compound's efficiency at modulating immune function. Particular replacement compounds are selected for further in vivo validation and dosage/administration optimization. Finally, the replacement compounds are used to treat a wide range of diseases, including inflammatory and autoimmune diseases

Claim (Index 1):
A method for binding human low affinity Fc\u03b3 receptors (Fc\u03b3R) on effector cells comprising administering a recombinantly produced biomimetic composition to a population of effector cells, wherein the biomimetic composition comprises two or more human IgG4 Fc domains wherein each of the two or more IgG4 Fc domains is capable of binding to a human low affinity Fc\u03b3R, wherein the biomimetic composition binds to two or more human low affinity Fc\u03b3Rs, and wherein the biomimetic composition does not comprise either an antigen binding domain or a non-immunoglobulin protein, and wherein the human low affinity Fc\u03b3R is an Fc\u03b3RIIA, an Fc\u03b3RIM, an Fc\u03b3RIIIA, or an Fc\u03b3RIIIB receptor.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 88.0
- Lexical Diversity: 1.33333
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15483873', '12602609', '14221148', '14032597', '13971584']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8575662015664917
- 35 USC 102 Novelty (BERT): 0.7863145488898284
- Combined Prediction Score: 0.8504410362988253
- Mean Citation Score: 747.057564
- Max Citation Score: 938.06476
- Similarity Product: 912.9828516214658

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test