PATENT CLAIM ANALYSIS

Application Number: 16125645
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["546", "169000"]

Abstract:
The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.

Claim (Index 12):
A method for treatment and/or prevention of a disease or a disorder in a human or an animal comprising administering to the human or animal in need thereof a compound of the formula (I) in which R A  is hydrogen, halogen, pentafluorosulfanyl, cyano, nitro, (C 1 -C 4 )-alkyl, hydroxyl, (C 1 -C 4 )-alkoxy, amino or a group of the formula \u2014NH\u2014C(\u2550O)\u2014R 6 , \u2014NH\u2014C(\u2550O)\u2014NH\u2014R 6  or \u2014S(\u2550O) n \u2014R 7 ,\n where (C 1 -C 4 )-alkyl and (C 1 -C 4 )-alkoxy may be up to trisubstituted by fluorine, \n and in which \n R 6  is hydrogen or (C 1 -C 4 )-alkoxy which may be up to trisubstituted by fluorine, \n R 7  is (C 1 -C 4 )-alkyl which may be substituted by hydroxyl, methoxy or ethoxy or up to trisubstituted by fluorine, \n and \n n is the number 0, 1 or 2, \n D is C\u2014R D  or N, E is C\u2014R E  or N, G is C\u2014R G  or N,\n where not more than two of the ring members D, E and G at the same time are N, \n and in which \n R D  and R E  are each independently hydrogen, fluorine, chlorine, methyl, trifluoromethyl, methoxy or trifluoromethoxy, \n and \n R G  is hydrogen, fluorine, chlorine, bromine, methyl or trifluoromethyl, \n Z is OH or a group of the formula \u2014NH\u2014R 8 , \u2014NH\u2014SO 2 \u2014R 9  or \u2014NH\u2014SO 2 \u2014NR 10A R 10B , in which\n R 8  is hydrogen or (C 1 -C 4 )-alkoxy which may be up to trisubstituted by fluorine, \n R 9  is (C 1 -C 4 )-alkoxy which may be up to trisubstituted by fluorine, or phenyl, \n and \n R 10A  and R 10B  are each independently hydrogen or (C 1 -C 4 )-alkyl which may be up to trisubstituted by fluorine, \n R 1  is halogen, trifluoromethoxy, (trifluoromethyl)sulfanyl, pentafluorosulfanyl, (C 1 -C 4 )-alkyl, trimethylsilyl, cyclopropyl or cyclobutyl,\n where (C 1 -C 4 )-alkyl may be up to trisubstituted by fluorine and \n cyclopropyl and cyclobutyl may be up to disubstituted by fluorine, \n R 2 , R 3  and R 4  are each independently hydrogen, fluorine, chlorine, methyl or trifluoromethyl, R 5  is (C 1 -C 4 )-alkyl which may be up to trisubstituted by fluorine, or is fluorine, chlorine, methoxy or cyclopropyl, and Ar is phenyl which may be mono- or disubstituted identically or differently by fluorine and chlorine, or is pyridyl or thienyl, and the N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts thereof.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 97.0
- Lexical Diversity: 1.75758
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15735138', '13819337', '15288982', '15288968', '14895793']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8246074548902947
- 35 USC 102 Novelty (BERT): 0.5468911492711815
- Combined Prediction Score: 0.7968358243283834
- Mean Citation Score: 423.186078
- Max Citation Score: 441.07358
- Similarity Product: 295.10815611861227

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test