PATENT CLAIM ANALYSIS

Application Number: 15937446
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["435", "091100"]

Abstract:
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.

Claim (Index 17):
A direct blood draw tube comprising:\n a composition formulated for stabilizing a direct drawn blood sample having cell-free nucleic acids within plasma of the blood sample while the blood sample is in the tube including:\n b) ethylenediaminetetraacetic acid (EDTA); \n c) one or more solvents; \n d) less than or up to about 1% formaldehyde as a result of the at least two formaldehyde releaser preservative agents; \n wherein an amount of the at least two formaldehyde releaser preservative agents within the direct blood draw tube prior to blood draw is an amount of about 50 to about 500 grams per liter; wherein an amount of the composition is in an amount so that any consequential dilution of the blood sample is substantially avoided, and cell-free nucleic acids in the blood sample are not materially diluted; and wherein at least about 7 days can elapse between a time of blood draw and a time of any testing or screening of a drawn blood sample, and or isolation of the cell-free nucleic acids.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 1.6
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15601682', '15894077', '14071969', '12704030', '13648415']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6052746661517335
- 35 USC 102 Novelty (BERT): 0.5674344372127396
- Combined Prediction Score: 0.6014906432578341
- Mean Citation Score: 384.25828999999993
- Max Citation Score: 451.23248
- Similarity Product: 393.95762272320746

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test