PATENT CLAIM ANALYSIS

Application Number: 16006308
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["549", "059000"]

Abstract:
The present invention relates to certain novel substituted thiophene compounds and the finding that they display useful efficacy in the inhibition of the p38α MAPK enzyme. This provides for use of the compounds in various treatment methodologies related to MAPK inhibition, including the treatment of inflammation.

Claim (Index 1):
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein, R 1  is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, alkanoyl, carboalkoxy, acyloxy, aryl, aroyl, heteroaryl, heteroaroyl, heterocyclyl, heterocycloyl, cycloalkyl, O-alkyl and O-aryl, O-heteroaryl, amino and amido, all of which groups may be substituted or unsubstituted; R 2  is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, aryl, alkylaryl, heterocyclyl and heteroaryl, all of which may be substituted or unsubstituted; and R 3  and R 4  are independently selected from the group consisting of aryl, heteroaryl, heterocyclyl and cycloalkyl, all of which groups may be substituted or unsubstituted.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 94.0
- Lexical Diversity: 1.36111
- Patent Class: 549.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13652247', '15346443', '15048330', '12477715', '14263822']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7932701372478181
- 35 USC 102 Novelty (BERT): 0.5074478376733412
- Combined Prediction Score: 0.7646879072903705
- Mean Citation Score: 299.0853620000001
- Max Citation Score: 302.8737799999999
- Similarity Product: 274.5171293400716

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test