PATENT CLAIM ANALYSIS

Application Number: 15919640
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["435", "006120"]

Abstract:
The present disclosure provides methods, arrays and kits for assessing the quality of genomic DNA samples, especially those obtained from formalin-fixed paraffin-embedded (FFPE) samples. The methods, arrays and kits provided herein use primer pairs specific to regions in the genomes of the organisms from which genomic DNA samples are obtained that have identical or nearly identical copies distributed across multiple chromosomes.

Claim (Index 3):
The method of  claim 1 , having one or more of the following characteristics:\n i) the genomic DNA fragments amplified by multiple primer pairs are present in more than 50%, 60%, 70% or more than 80% of all autosomes of the organism from which the DNA sample is obtained; ii) the genomic DNA fragments amplified are not present on sex chromosomes; iii) no more than 50 percent, 40 percent, 30 percent or 20 percent of the genomic DNA fragment amplified by the multiple primer pairs are located on a single chromosome; iv) the genomic DNA fragments amplified in step (a) are between about 100 to 400 bp in length; v) the genomic DNA fragments amplified in the presence of a particular primer pair are present at 3 or more different autosomes, wherein preferably, no more than 50 percent, 40 percent, 30 percent or 20 percent of the genomic DNA fragment amplified by the particular primer pair are located on a single chromosome; and/or vi) the number of the primer pairs is 2-12 or 4-8.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.36
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14208460', '14652098', '14775435', '14864158', '12678423']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5954514163138568
- 35 USC 102 Novelty (BERT): 0.6095998990184637
- Combined Prediction Score: 0.5968662645843175
- Mean Citation Score: 403.928404
- Max Citation Score: 607.0267
- Similarity Product: 451.9427278871357

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test