PATENT CLAIM ANALYSIS

Application Number: 15880889
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-10
Patent Classification: ["424", "489000"]

Abstract:
The present disclosure provides for palonosetron formulations, such as aerosol formulations of palonosetron for pulmonary delivery. Also provided are uses of the formulation, such as reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, or surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

Claim (Index 1):
An inhalation formulation comprising i) palonosetron or a pharmaceutically acceptable salt thereof, and ii) an excipient that comprises a fine powder and a coarse powder, and wherein the formulation exhibits a minimum fine particle fraction (FPF) of at least 40%; and wherein palonosetron is about 0.5% to about 4% of the total composition of formulation; and the fine powder and coarse powder are present in a mass ratio of about 1:14, 1:10, 1:9, 1:4, or 1:2.5.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 86.0
- Lexical Diversity: 1.72917
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15154431', '15611785', '14855564', '14202262', '15351562']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6746190554049132
- 35 USC 102 Novelty (BERT): 0.5286143585751991
- Combined Prediction Score: 0.6600185857219418
- Mean Citation Score: 231.746164
- Max Citation Score: 325.56503
- Similarity Product: 231.22651465899827

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test