PATENT CLAIM ANALYSIS

Application Number: 15913392
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-03
Patent Classification: ["514", "049000"]

Abstract:
Disclosed are methods for preventing metastasis of cancer cells. The disclosed compounds can be used to prevent the spread of tumor or other types of cancer cells.

Claim (Index 21):
A method for treating an ocular condition comprising administering to a subject in need thereof:\n a) a therapeutically-effective amount of a compound; and b) a therapeutically-effective amount of an anti-VEGF agent, wherein the compound has the formula: wherein R is a substituted or unsubstituted thiazolyl unit having the formula: R 2 , R 3 , and R 4  are each independently:\n i) hydrogen; \n ii) substituted or unsubstituted C 1 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkyl; \n iii) substituted or unsubstituted C 2 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkenyl; \n iv) substituted or unsubstituted C 2 -C 6  linear or C 3 -C 6  branched alkynyl; \n v) substituted or unsubstituted C 6  or C 10  aryl; \n vi) substituted or unsubstituted C 1 -C 9  heteroaryl; \n vii) substituted or unsubstituted C 1 -C 9  heterocyclic; or \n viii) R 2  and R 3  taken together form a saturated or unsaturated ring having from 5 to 7 atoms; wherein from 1 to 3 atoms can optionally be oxygen, nitrogen, or sulfur; \n Z is a unit having the formula:\n -(L) n -R 1  \n R 1  is:\n i) hydrogen; \n ii) hydroxyl; \n iii) amino; \n iv) substituted or unsubstituted C 1 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkyl; \n vi) substituted or unsubstituted C 1 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkoxy; \n vi) substituted or unsubstituted C 6  or C 10  aryl; \n vii) substituted or unsubstituted C 1 -C 9  heterocyclic rings; or \n viii) substituted or unsubstituted C 1 -C 9  heteroaryl rings; \n L is a linking unit having the formula:\n -[Q] y [C(R 5a R 5b )] x [Q 1 ] z [C(R 6a R 6b )] w \u2014 \n Q and Q 1  are each independently:\n i) \u2014C(O)\u2014; \n ii) \u2014NH\u2014; \n iii) \u2014C(O)NH\u2014; \n iv) \u2014NHC(O)\u2014; \n v) \u2014NHC(O)NH\u2014; \n vi) \u2014NHC(O)O\u2014; \n vii) \u2014C(O)O\u2014; \n viii) \u2014C(O)NHC(O)\u2014; \n ix) \u2014O\u2014; \n x) \u2014S\u2014; \n xi) \u2014SO 2 \u2014; \n xii) \u2014C(\u2550NH)\u2014; \n xiii) \u2014C(\u2550NH)NH\u2014; \n xiv) \u2014NHC(\u2550NH)\u2014; or \n xv) \u2014NHC(\u2550NH)NH\u2014; \n R 5a  and R 5b  are each independently:\n i) hydrogen; \n ii) hydroxy; \n iii) halogen; \n iv) substituted or unsubstituted C 1 -C 6  linear or C 3 -C 6  branched alkyl; or \n v) a unit having the formula:\n \u2014[C(R 7a R 7b )] t R 8  \n \n R 7a  and R 7b  are each independently:\n i) hydrogen; or \n ii) substituted or unsubstituted C 1 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkyl; \n R 8  is:\n i) hydrogen; \n ii) substituted or unsubstituted C 1 -C 6  linear, C 3 -C 6  branched, or C 3 -C 6  cyclic alkyl; \n iii) substituted or unsubstituted C 6  or C 10  aryl; \n iv) substituted or unsubstituted C 1 -C 9  heteroaryl; or \n v) substituted or unsubstituted C 1 -C 9  heterocyclic; \n R 6a  and R 6b  are each independently:\n i) hydrogen; or \n ii) C 1 -C 4  linear or C 3 -C 4  branched alkyl; \n the index n is 0 or 1; the indices t, w and x are each independently from 0 to 4; the indices y and z are each independently 0 or 1; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 90.0
- Lexical Diversity: 1.20833
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12677550', '13783311', '14272689', '14864462', '13724396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7849993271513769
- 35 USC 102 Novelty (BERT): 0.6345801215622898
- Combined Prediction Score: 0.7699574065924681
- Mean Citation Score: 549.348382
- Max Citation Score: 620.8644400000002
- Similarity Product: 557.453521983967

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test