PATENT CLAIM ANALYSIS

Application Number: 15753865
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-05
Patent Classification: ["514", "04400A"]

Abstract:
Provided herein are methods for the treatment of poly-cystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.

Claim (Index 13):
The method of  claim 1 , wherein the administering:\n a) improves kidney function in the subject; b) delays the worsening of kidney function in the subject; c) reduces total kidney volume in the subject; d) slows the increase in total kidney volume in the subject; e) inhibits cyst growth in the subject; f) slows the increase in cyst growth in the subject; g) reduces kidney pain in the subject; h) slows the increase in kidney pain in the subject; i) delays the onset of kidney pain in the subject; j) reduces hypertension in the subject; k) slows the worsening of hypertension in the subject; l) delays the onset of hypertension in the subject; m) reduces fibrosis in the kidney of the subject; n) slows the worsening of fibrosis in the kidney of the subject; o) delays the onset of end stage renal disease in the subject; p) delays time to dialysis for the subject; q) delays time to renal transplant for the subject; and/or r) improves life expectancy of the subject.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 88.0
- Lexical Diversity: 1.13043
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14048827', '14872564', '15380629', '13811423', '14334872']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8224212591277004
- 35 USC 102 Novelty (BERT): 0.5425258982975101
- Combined Prediction Score: 0.7944317230446813
- Mean Citation Score: 364.996002
- Max Citation Score: 393.703
- Similarity Product: 307.5486481387615

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test