PATENT CLAIM ANALYSIS

Application Number: 16230512
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["424", "191100"]

Abstract:
The present invention provides polypeptides useful as antigens expressed at the pre-erythrocytic stage of the malaria parasite. The antigens can be utilized to induce an immune response and sterile protection against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other recombinant protein expression systems delivered as a vaccine formulation.

Claim (Index 32):
A method of inducing an immune response against malaria in a subject, comprising administering to the subject an immunogenic composition comprising:\n (a) a recombinant polypeptide;\n wherein the recombinant polypeptide comprises SEQ ID NO:3, or a recombinant polypeptide that comprises at least 10 contiguous amino acids of SEQ ID NO:3 and has at least 85% sequence identity with SEQ ID NO:3; \n (b) a pharmaceutical acceptable carrier; and \n (c) an adjuvant; \n wherein the immunogenic composition further comprises one or more additional recombinant polypeptides, wherein the one or more additional recombinant polypeptides comprise an amino acid sequence selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9, or a recombinant polypeptide that comprises at least 10 contiguous amino acids of SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9 and has at least 85% sequence identity with one of SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 98.0
- Lexical Diversity: 1.32609
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15431609', '14219390', '12928044', '11143986', '11975396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7885387044795286
- 35 USC 102 Novelty (BERT): 0.7018605120028917
- Combined Prediction Score: 0.7798708852318649
- Mean Citation Score: 510.18833400000005
- Max Citation Score: 789.22186
- Similarity Product: 723.3526719481731

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test