PATENT CLAIM ANALYSIS

Application Number: 16051725
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["424", "186100"]

Abstract:
An aspect of the present invention is directed towards DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of influenza virus subtypes, comprising a DNA plasmid and a pharmaceutically acceptable excipient. The DNA plasmid is capable of expressing a consensus influenza antigen in a cell of the mammal in a quantity effective to elicit an immune response in the mammal, wherein the consensus influenza antigen comprises consensus hemagglutinin (HA), neuraminidase (NA), matrix protein, nucleoprotein, M2 ectodomain-nucleo-protein (M2e-NP), or a combination thereof. Preferably the consensus influenza antigen comprises HA, NA, M2e-NP, or a combination thereof. The DNA plasmid comprises a promoter operably linked to a coding sequence that encodes the consensus influenza antigen. Additionally, an aspect of the present invention includes methods of eliciting an immune response against a plurality of influenza virus subtypes in a mammal using the DNA plasmid vaccines provided.

Claim (Index 70):
The composition of  claim 54 , comprising a plurality of different DNA plasmids;\n Wherein one of the plurality of DNA plasmids comprises the nucleotide sequence that encodes the consensus NA, one of the plurality of DNA plasmids comprises the nucleotide sequence that encodes the consensus M2e-NP, and one of the plurality of DNA plasmids comprises a nucleotide sequence that encodes a consensus hemagglutinin (HA) antigen.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 96.0
- Lexical Diversity: 2.36111
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15416604', '12269824', '13158150', '13131733', '12375518']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8291639799165409
- 35 USC 102 Novelty (BERT): 0.6332784620675911
- Combined Prediction Score: 0.809575428131646
- Mean Citation Score: 618.231768
- Max Citation Score: 780.27844
- Similarity Product: 538.2072515681839

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test