PATENT CLAIM ANALYSIS

Application Number: 15860175
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["435", "006100"]

Abstract:
Molecular signatures that function as very sensitive diagnostic biomarker for myocarditis, heart disease and disorders thereof, are identified.

Claim (Index 34):
A method of treating a patient with myocarditis comprising:\n obtaining a sample from the patient; measuring the expression of a set of genes in the sample to create a patient gene expression profile, wherein the gene expression profile consists of the expression of (1552302_at) FLJ77644, TMEM106A; (1552310_at) C15orf40, (1553212_at) KRT78, (1555349_a_at) ITGB2, (1555878_at) RPS24, (1556033_at) NA, (1556507_at) NA, (1558605_at) NA (1559224_at) LCE1E, (1562785_at) HERC6, (1565662_at) NA, (15658300 NA, (202375_at) SEC24D, (202445_s_at) NOTCH2, (203741_s_at) ADCY7, (204222_s_at) GLIPR1, (206052_s_at) SLBP, (206333_at) MSI1, (206770_s_at) SLC35A3, (209307_at) SWAP70, (211089_s_at) NEK3, (211341_at) LOC100131317, POU4F1; (212511_at) PICALM, (212830_at) MEGF9, (212999_x_at) hCG.sub.-1998957, HLA-DQB1/2, HLA-DRB1/23/4/5; (213501_at) ACOX1, (213831_at) HLA-DQA1, (217054_at) NA, (217182_at) MUC5AC, (217322_x_at) NA, (217777_s_at) PTPLAD1, (218803_at) CHFR, (219425_at) SULT4A1, (221663_x_at) HRH3, (223077_at) TMOD3, (224327_s_at) DGAT2, (224996_at) Na, (225579_at) PQLC3, (226240_at) MGC21874, (227280 s_at) CCNYL1, (227618_at) Na, (227983_at) RILPL2, (228980_at) RFFL, (229191_at) TBCD, (230836_at) ST8SIA4, (231599_x_at) DPF1, (234495_at) KLK15, (234986_at) NA, (234987_at) NA, (236232_at) STX4, (236404_at) NA, (236698_at) NA, (238327_at) LOC440836, (238445_x_at) MGAT5B, (239463_at) NA, (242383_at) NA, (242563_at) NA, (243819_at) NA, (244841_at) SEC24A, (32069_at) N4BP1, (44673_at) SIGLEC1, and (53720_at) C19orf66; and comparing the gene expression profile to a myocarditis gene expression profile positive control, wherein the patient is identified as having myocarditis when the patient gene expression profile is the same as the myocarditis gene expression profile positive control; and treating the patient identified has having myocarditis.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.05
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14334024', '13836535', '13635667', '13636958', '15814200']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5618371321454795
- 35 USC 102 Novelty (BERT): 0.5034514623371007
- Combined Prediction Score: 0.5559985651646416
- Mean Citation Score: 196.976114
- Max Citation Score: 265.41528
- Similarity Product: 185.7509213975286

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test