PATENT CLAIM ANALYSIS

Application Number: 16266867
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["433", "175000"]

Abstract:
A method for reconstructing a functional tooth by using a carrier loaded with a plurality of mesenchymal stem cells including at least one of a stem cell derived from Apical Papilla (SCAP), Periodontal Ligament Stem Cells (PDLSC), and Dental Pulp Stem Cells (DPSC). The mesenchymal stem cell loaded carrier is planted into a site within a subject's oral cavity to form a bio-root upon which a crown may be affixed, The mesenchymal stem cells will develop new periodontal tissues to stabilize the bio-root. Methods disclosed herein are particularly beneficial for subjects lacking good bone structures for conventional crown treatments.

Claim (Index 18):
A stem cell composition, comprising:\n two stem cell compositions, wherein the first stem cell composition comprises plurality of human apical papilla stem cells (SCAP), and the second stem cell composition comprises human periodontal ligament stem cells (PDLSC); wherein the SCAP are: isolated from root apical papilla of a tooth extracted from an adult human; characterized by expression of STRO-1, CD146, CD166 and CD24-positive surface markers; and capable of differentiating into odontoblastic or osteoblastic cells.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 99.0
- Lexical Diversity: 1.41772
- Patent Class: 433.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12514051', '11433627', '14936529', '10553633', '14869565']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6994112229325853
- 35 USC 102 Novelty (BERT): 0.6172162261605798
- Combined Prediction Score: 0.6911917232553847
- Mean Citation Score: 461.43858
- Max Citation Score: 681.13745
- Similarity Product: 494.77768737686864

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test