PATENT CLAIM ANALYSIS

Application Number: 16293749
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-06
Patent Classification: ["424", "139100"]

Abstract:
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Claim (Index 1):
A method of eliciting an immune response in a patient who has cancer, comprising administering to the patient an effective amount of an antibody specifically binding to an MHC class I or II molecule complexed with a HLA-restricted antigen consisting of the amino acid sequence selected from SEQ ID NO: 157, from SEQ ID NO: 1 to SEQ ID NO: 156, and from SEQ ID NO: 158 to SEQ ID NO: 288,\n wherein said cancer is selected from the group consisting of hepatocellular carcinoma (HCC), colorectal carcinoma (CRC), glioblastoma (GB), gastric cancer (GC), esophageal cancer (OSCAR), non-small cell lung cancer (NSCLC), pancreatic cancer (PC), renal cell carcinoma (RCC), benign prostate hyperplasia (BPH), prostate cancer (PCA), ovarian cancer (OC), melanoma, breast cancer (BRCA), chronic lymphocytic leukemia (CLL), Merkel cell carcinoma (MCC), small cell lung cancer (SCLC), Non-Hodgkin lymphoma (NHL), acute myeloid leukemia (AML), gallbladder cancer and cholangiocarcinoma (GBC CCC), urinary bladder cancer (UBC), and uterine cancer (UTC).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 99.0
- Lexical Diversity: 1.61972
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16152122', '16227228', '16126663', '15917159', '15956638']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8604025209485563
- 35 USC 102 Novelty (BERT): 0.6425739839228505
- Combined Prediction Score: 0.8386196672459857
- Mean Citation Score: 688.617892
- Max Citation Score: 690.2773
- Similarity Product: 589.1085216985047

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test