PATENT CLAIM ANALYSIS

Application Number: 15918098
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["514", "028000"]

Abstract:
Described herein are pharmaceutical compositions adapted for the parenteral administration of macrolide antibiotics, such as triazole-containing and fluoroketolide antibiotics. Also described herein are methods for their use in the treatment of bacterial, protozoal, and other infections.

Claim (Index 1):
A pharmaceutical composition adapted for parenteral administration comprising one or more antibacterial compounds of the formula or a pharmaceutically acceptable salt thereof, and combinations thereof, wherein:\n R 10  is hydrogen or acyl; \n X is H; and Y is OR 7 ; where R 7  is a monosaccharide or disaccharide, alkyl, aryl, heteroaryl, acyl, or C(O)NR 8 R 9 , where R 8  and R 9  are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, heteroalkyl, aryl, heteroaryl, alkoxy, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; or X and Y are taken together with the attached carbon to form carbonyl; \n V is C(O), C(\u2550NR 11 ), CH(NR 12 , R 13 ), or \u2014N(R 14 )CH 2 , where N(R 14 ) is attached to the C-10 carbon of the compound; wherein R 11  is hydroxy or alkoxy, R 12  and R 13  are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; R 14  is hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, or carbamoyl; \n W is H, F, Cl, Br, I, or OH; \n A is CH 2 , C(O), C(O)O, C(O)NH, S(O) 2 , S(O) 2 NH, C(O)NHS(O) 2 ; \n B is (CH 2 ) n  where n is an integer ranging from 0-10, or B is an unsaturated carbon chain of 2-10 carbons; and \n C is hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, aminoaryl, alkylaminoaryl, acyl, acyloxy, sulfonyl, ureido, or carbamoyl; and \n a tartaric acid or a salt thereof.

Metadata:
- Claim Count in Document: 52.0
- Percentile: 90.0
- Lexical Diversity: 1.32258
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14387643', '13125555', '14309202', '13722058', '14774843']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7285571169984743
- 35 USC 102 Novelty (BERT): 0.547171524892774
- Combined Prediction Score: 0.7104185577879043
- Mean Citation Score: 301.993014
- Max Citation Score: 391.29068
- Similarity Product: 291.8162001216316

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test