PATENT CLAIM ANALYSIS

Application Number: 15982284
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "182000"]

Abstract:
A process is provided for the making of estetrol starting from a 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one, wherein A is an C 1 -C 5  alkyl group, preferably a methyl group, or a C 7 -C 12  benzylic group, preferably a benzyl group. This process is particularly suitable to industry.

Claim (Index 1):
A process the preparation of 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one, comprising:\n (a) converting the 17-keto group of estrone into a protected keto group to form 17-D-estra-1,3,5(10)-trien-3-ol; (b) converting the 3-OH group of 17-D-estra-1,3,5(10)-trien-3-ol into a 3-AO group to form 3-A-oxy-17-D-estra-1,3,5(10)-trien-17-one; (c) halogenating C 16  of 3-A-oxy-17-D-estra-1,3,5(10)-triene to form 3-A-oxy-16-X-17-D-estra-1,3,5(10)-triene wherein X is a halogen atom selected from the group chloride, bromide and iodide; (d) dehalogenating 3-A-oxy-16-X-17-D-estra-1,3,5(10)-triene to 3-A-oxy-17-D-estra-1,3,5(10),15-tetraene; and (e) deprotecting the protected keto group of 3-A-oxy-17-D-estra-1,3,5(10),15-tetraene to form 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one; wherein A is selected from an C 1 -C 5  alkyl group or a C 7 -C 12  benzylic group, and wherein D is ethylene dioxy.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 1.4359
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14578137', '15022177', '14349940', '14414386', '14348645']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7786504891488675
- 35 USC 102 Novelty (BERT): 0.6141011361310722
- Combined Prediction Score: 0.7621955538470879
- Mean Citation Score: 385.3668799999999
- Max Citation Score: 575.4507
- Similarity Product: 501.76679348216055

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test