PATENT CLAIM ANALYSIS

Application Number: 16468658
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-10
Patent Classification: ["514", "249000"]

Abstract:
The present invention provides a compound having a structure shown in formula (I) or an isomer, pharmaceutically acceptable solvate, or salt thereof. The compound is used as a Bruton's tyrosine kinase inhibitor, and has a higher inhibitory activity against BTK and less adverse effects.

Claim (Index 18):
The method according to  claim 17 , wherein, the BTK-mediated disease is selected from the group consisting of rheumatoid arthritis, infectious arthritis, teratogenic arthritis, gouty arthritis, spondylitis, pancreatitis, chronic bronchitis, acute bronchitis, allergic bronchitis, toxic bronchitis, pediatric asthma, allergic alveolitis, allergic or non-allergic rhinitis, chronic nasosinusitis, cystic fibrosis or mucous viscous disease, cough, emphysema, interstitial lung disease, alveolitis, nasal polyps, pulmonary edema, pneumonia of various causes, lupus erythematosus, systemic scleroderma, sarcoidosis, subtypes of diffuse large B-cell lymphoma, mantle cell lymphoma (MCL), chronic lymphocytic lymphoma, extranodal marginal zone B-cell lymphoma, B-cell chronic lymphocytic leukemia (CLL), B-cell prolymphocytic leukemia, mature B-cell acute lymphoblastic leukemia, 17p-deletion chronic lymphocytic leukemia, Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, splenic marginal zone lymphoma, plasma cell myeloma, plasmacytoma, intranodal marginal zone B-cell lymphoma, mantle cell lymphoma, intravascular large B-cell lymphoma and primary effusion lymphoma and combinations thereof.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 100.0
- Lexical Diversity: 1.2381
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16191190', '15969864', '15762367', '14228184', '13436963']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8050746405158301
- 35 USC 102 Novelty (BERT): 0.5184581051130703
- Combined Prediction Score: 0.776412986975554
- Mean Citation Score: 288.591296
- Max Citation Score: 311.26706
- Similarity Product: 212.08522282006743

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test