PATENT CLAIM ANALYSIS

Application Number: 16105290
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["424", "093700"]

Abstract:
The invention relates to forming locus-specific (or gene-specific) pools of cells from various potential donors, where the cells that express or display HLA molecules, or other polymorphic cell surface markers, and identifying the pattern of responses across these pools, notably aggregation of cells, or their acquisition of fluorescence when exposed to a labeled secondary antibody, when exposed to sera from a potential recipient. Pools of cells from different potential donors are designed and constructed in accordance with allele partitions that are identified by amino acid sequence tags, preferably defined in terms of single or combinations of variable amino acid positions encoded by the constituent alleles in the partition.

Claim (Index 12):
The method of  claim 7  wherein if the highest-ranked pool contains a population of non-aggregated cells, or the lowest-ranked pool contains a population of aggregated cells, new pools containing cells having additional alleles encoding additional antigenic determinants are prepared and steps (ii) to (vi) above are repeated using said new pools.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 96.0
- Lexical Diversity: 1.54545
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15202035', '14441187', '09869003', '14102571', '13044430']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7242010763626475
- 35 USC 102 Novelty (BERT): 0.5126472495346712
- Combined Prediction Score: 0.7030456936798499
- Mean Citation Score: 208.726578
- Max Citation Score: 259.40652
- Similarity Product: 163.9439386280322

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test