PATENT CLAIM ANALYSIS

Application Number: 16017815
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-05
Patent Classification: ["435", "287200"]

Abstract:
The present disclosure relates to lateral flow methods and apparatuses for detecting one or more analytes. Certain embodiments provide a lateral flow device, kit and method of using the same, comprising: a flow path defined by a permeable sub-assembly of the lateral flow device, a release zone comprising a plurality of peptide-tagged agents, and a detection zone comprising a plurality of anti-peptide agents present in the flow path at a ratio of at least 100:1, on a weight:weight basis, relative to the plurality of peptide-tagged agents.

Claim (Index 21):
A method to detect a predetermined analyte, comprising:\n i) providing:\n a) a first permeable release member comprising a plurality of first peptide-tagged agents and a plurality of detectable agents; \n b) a universal detection member in fluid communication with the first permeable release member, the universal detection member comprising a porous membrane and a plurality of anti-peptide agents bound to the porous membrane, the plurality of anti-peptide agents present at a ratio of at least 200:1 on a weight:weight basis, relative to the plurality of first peptide-tagged agents, the plurality of first peptide-tagged agents having a plurality of covalently conjugated peptide tags; and \n c) an absorbent wicking pad in fluid communication with the universal detection member; \n ii) contacting the first permeable release member with a sample, the sample comprising the predetermined analyte; iii) forming an analyte complex comprising the predetermined analyte bound to at least one of the plurality of first peptide-tagged agents and separately bound to at least one of the plurality of detectable agents; iv) passively transporting the analyte complex by capillary flow action to the universal detection member; v) immobilizing the analyte complex to the universal detection member by selectively binding at least one of the plurality of covalently conjugated peptide tags with at least one of the plurality of anti-peptide agents; and vi) detecting the immobilized analyte complex by detecting the at least one of the plurality of detectable agents.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 94.0
- Lexical Diversity: 1.86538
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14641942', '15073326', '14940983', '13436764', '12721784']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5732239514552925
- 35 USC 102 Novelty (BERT): 0.4927073135018659
- Combined Prediction Score: 0.5651722876599498
- Mean Citation Score: 183.493898
- Max Citation Score: 195.57706
- Similarity Product: 124.82148504941463

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test