PATENT CLAIM ANALYSIS

Application Number: 16012002
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["435", "173600"]

Abstract:
A new simple transfection method using an integrated electrowetting nano-injector (“INENI”) with controlled dosage delivery and high transfection efficiency is disclosed. The volume of delivery can be controlled via voltage application to an inner and outer electrode integrated into a nano-pipette. With higher voltages, more liquid enters the INENI and with lower voltages liquid is expelled. This method can be used to deliver plasmid DNA directly into the nuclei of cells. The INENI requires only the use of a single probe since both electrodes are integrated into the same nano-pipette. Hence, more space is available, and ergo the INENI offers a simplistic means for direct injection of metered amounts of exogenous material into the confines of a cell cytoplasm and/or nucleus while retaining full cell viability.

Claim (Index 6):
The system of  claim 5 , wherein the aqueous solution ( 104 ) is a DNA vector extracted from or injected into the nucleus of the living cell.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 94.0
- Lexical Diversity: 1.52747
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14282630', '15809702', '10560301', '13406269', '14775168']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5890198557877604
- 35 USC 102 Novelty (BERT): 0.4940215325231255
- Combined Prediction Score: 0.5795200234612969
- Mean Citation Score: 152.523126
- Max Citation Score: 156.78734
- Similarity Product: 93.23544681619406

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test