PATENT CLAIM ANALYSIS

Application Number: 15749168
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "325000"]

Abstract:
CRISPR/Cas Systems are provided where two or more guide RNAs having different spacer sequence lengths direct an enzymatically active Cas9 having a transcriptional regulator attached thereto to either cut a target nucleic acid or regulate expression of a target nucleic acid.

Claim (Index 1):
A method of modulating expression of a target nucleic acid in a cell comprising\n providing to the cell an enzymatically active Cas9 optionally having a transcriptional regulator attached thereto, providing to the cell a guide RNA having a spacer sequence of 14 to 8 nucleotides wherein the guide RNA and the enzymatically active Cas9 optionally having a transcriptional regulator attached thereto form a co-localization complex with the target nucleic acid and wherein complex formation of the cas9 and the guide RNA at the target nucleic acid regulates expression of the target nucleic acid or the transcriptional regulator, if present, regulates expression of the target nucleic acid.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.2
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14319289', '15049451', '14674895', '14903728', '14105017']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6958988815808752
- 35 USC 102 Novelty (BERT): 0.5718407397069457
- Combined Prediction Score: 0.6834930673934823
- Mean Citation Score: 478.90802600000006
- Max Citation Score: 500.33353
- Similarity Product: 398.91573508811234

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test