PATENT CLAIM ANALYSIS

Application Number: 16016540
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "186100"]

Abstract:
Provided are compositions and methods that involve recombinant Newcastle disease viruses (rNDVs), and recombinant vectors that encode them. The rNDVs comprise and/or encode a combination of at least two proteins that are hemagglutinin (HA), neuraminidase (NA) protein, matrix 1 protein (M1), or nonstructural 1 protein (NS1). The HA, NA, protein, M1, and nonstructural 1 protein (NS1) are from Avian Influenza virus (AIV). Method are provided and involve administering an immunologically effective amount rNDV to avian animals to stimulate a protective immune response the rNDV administration constitutes a first (prime) immunization, which can be followed by a second (boost) administration with an avirulent NVD that may include/encode an AIV HA. The avian animals can survive challenges from pathogenic and highly pathogenic NVD and AIV.

Claim (Index 13):
The method of  claim 10 , wherein at least one of the following is true: the avian animals survive exposure to pathogenic AIV or pathogenic NDV, or both, or exhibit reduced clinical signs of AIV or NDV infection, or both, or exhibit reduced AIV, reduced NDV shedding, or both.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.89024
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15434353', '12753597', '14268302', '11633130', '15059927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7691508085131924
- 35 USC 102 Novelty (BERT): 0.5468913122574692
- Combined Prediction Score: 0.7469248588876201
- Mean Citation Score: 427.24732000000006
- Max Citation Score: 451.1641
- Similarity Product: 250.5578847375632

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test