PATENT CLAIM ANALYSIS

Application Number: 15933889
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "210200"]

Abstract:
The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Claim (Index 8):
A compound represented by the following formula (II-2): wherein Rx 2  is (1) an optionally halogenated C 1-6  alkyl group, (2) a C 1-6  alkoxy group optionally substituted by 1 to 5 substituents selected from\n (a) a halogen atom, and \n (b) a C 3-10  cycloalkyl group optionally substituted by 1 to 3 halogen atoms, \n (3) a 3- to 8-membered oxygen-containing monocyclic non-aromatic heterocyclyloxy group, (4) an optionally halogenated C 1-6  alkyl-carbonyl group, or (5) a C 3-10  cycloalkyl group; Ry 2  is (1) a cyano group, (2) a halogen atom, or (3) an optionally halogenated C 1-6  alkyl group; and Rz 2  is (1) a C 1-6  alkyl group optionally substituted by 1 to 3 substituents selected from\n (a) a halogen atom, \n (b) a hydroxy group, \n (c) a C 1-6  alkoxy group optionally substituted by 1 to 3 substituents selected from\n (i) a halogen atom, \n (ii) a C 1-6  alkyl-carbonyloxy group, and \n (iii) a C 1-6  alkoxy-carbonyloxy group, \n \n (d) a C 1-6  alkyl-carbonyloxy group, and \n (e) a 5- to 6-membered nitrogen-containing monocyclic aromatic heterocyclic group, \n (2) a C 3-10  cycloalkyl group optionally substituted by 1 to 3 substituents selected from\n (a) a halogen atom, \n (b) a hydroxy group, \n (c) a C 1-6  alkyl group optionally substituted by 1 to 3 C 1-6  alkoxy groups, and \n (d) a C 1-6  alkoxy group, \n (3) a C 1-6  alkoxy-carbonyl group, (4) a C 6-14  aryl group optionally substituted by 1 to 3 halogen atoms, (5) a 5- to 6-membered nitrogen-containing monocyclic aromatic heterocyclic group optionally substituted by 1 to 3 C 1-6  alkyl groups, or (6) a 3- to 8-membered oxygen-containing monocyclic non-aromatic heterocyclic group optionally substituted by 1 to 3 substituents selected from\n (a) a halogen atom, \n (b) a C 1-6  alkyl group optionally substituted by 1 to 3 substituents selected from a halogen atom and a C 1-6  alkoxy group, \n (c) a C 3-10  cycloalkyl group, \n (d) a cyano group, and \n (e) a deuterium atom, \n or a salt thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 1.35593
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15830634', '13201536', '14404126', '15563161', '15506380']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8417094749514188
- 35 USC 102 Novelty (BERT): 0.5638161731561999
- Combined Prediction Score: 0.8139201447718969
- Mean Citation Score: 428.920974
- Max Citation Score: 449.30573
- Similarity Product: 381.7148373127717

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test