PATENT CLAIM ANALYSIS

Application Number: 15885940
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
A method of preventing transmission of a retrovirus from a mother to her offspring, by treating the mother's host cells with a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and two or more different guide RNAs (gRNAs), wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) of the proviral DNA, and preventing transmission of the proviral DNA to the offspring.

Claim (Index 9):
The method of  claim 1 , wherein at least one of the gRNAs comprises a CRISPR RNA (crRNA) and a trans-activated small RNA (tracrRNA), which are expressed as separate nucleic acids.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 88.0
- Lexical Diversity: 1.54237
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14838057', '15148261', '14951240', '15864715', '15430218']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6916502471650364
- 35 USC 102 Novelty (BERT): 0.630644260189399
- Combined Prediction Score: 0.6855496484674727
- Mean Citation Score: 424.823792
- Max Citation Score: 596.8924599999998
- Similarity Product: 521.1462628592918

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test