PATENT CLAIM ANALYSIS

Application Number: 15961554
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["544", "193200"]

Abstract:
Disclosed herein are isotopically labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi, including  Aspergillus  species, such as by positron emission tomography (PET) scanning. In some examples, the disclosed compounds have a formula of wherein R 1  is an amine, a hydroxyl group, a sulfide, a carboxylic acid, an amide, an alkyl, or aryl; R 2  is —NHC(O)—R 3 -L or —C(O)NH—R 3 -L, wherein R 3  is an aryl or an aliphatic group (such as alkyl); each R 4  independently may be selected from halogen, aliphatic (such as alkyl), aryl, amine, hydroxyl, haloalkyl, carboxylic acid, amide, aralkyl, cyano, ester, thiol, thioether, or alkoxy; each R 5  independently may be selected from hydrogen, aralkyl, alkyl, or aryl, with any one of the aralkyl, alkyl, or aryl groups optionally being substituted with any one of the substituents provided for R 4 ; each n independently is 1, 2, 3, 4, or 5; and L is  18 F or a chelator capable of chelating a radiolabel (such as chelators for [ 18 F]AlF,  64 Cu,  68 Ga), 1,4,7,10-tetraazacyclododecane-tetraacetic acid (DOTA) or 1,4,7-triazacyclononane-triacetic acid (NOTA).

Claim (Index 13):
The method of  claim 6 , wherein the method is used to diagnose a pulmonary lung infection or a condition associated with a pulmonary lung infection.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 2.29091
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15030554', '14395377', '10632688', '12687008', '15585632']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.735705602277596
- 35 USC 102 Novelty (BERT): 0.544979409868191
- Combined Prediction Score: 0.7166329830366556
- Mean Citation Score: 244.34319400000004
- Max Citation Score: 402.67255
- Similarity Product: 219.81442768214345

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test