PATENT CLAIM ANALYSIS

Application Number: 15896543
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["435", "006100"]

Abstract:
The present disclosure provides methods and systems for nucleic acid processing. A method for preparing a sequencing set may include providing a template nucleic acid and amplifying the template nucleic acid to provide a complementary nucleic acid. Next, the complementary nucleic acid may be fragmented and barcoded to produce a first set of barcoded fragments comprising a plurality of first barcoded fragments. Next, the plurality of first barcoded fragments may be fragmented to yield a second set of barcoded fragments comprising a plurality of second barcoded fragments.

Claim (Index 18):
A method for preparing a set of nucleic acid molecules, comprising:\n (a) providing a plurality of nucleic acids of varying lengths, wherein each of said nucleic acids of varying lengths comprises a first target sequence; (b) providing a non-naturally occurring CRISPR-Cas complex which comprises (i) a Cas protein, (ii) a guide ribonucleic acid (RNA) capable of selectively coupling to said first target sequence, and (iii) an endonuclease, wherein said guide RNA binds said Cas protein, and wherein said Cas protein and said guide RNA do not naturally occur together; (c) bringing said plurality of said nucleic acids of varying lengths in contact with said CRISPR-Cas complex under conditions that permit said guide RNA to selectively couple to said first target sequence of said nucleic acids of varying lengths; and (d) cleaving said nucleic acids of varying lengths by said endonuclease, thereby providing said set of nucleic acid molecules.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 88.0
- Lexical Diversity: 2.325
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14990276', '15842687', '14804068', '15887947', '14995646']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5598723793016313
- 35 USC 102 Novelty (BERT): 0.5334972397717749
- Combined Prediction Score: 0.5572348653486456
- Mean Citation Score: 329.681028
- Max Citation Score: 384.0368
- Similarity Product: 286.9217201042176

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test