PATENT CLAIM ANALYSIS

Application Number: 16065397
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "387000"]

Abstract:
Presently provided are inhibitors of cellularly expressed TDO2 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2, 3 dioxygenase; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.

Claim (Index 2):
The compound of  claim 1  wherein\n R 1  is C 3-10 cycloalkyl, 3-7 membered heterocyclyl, \u2014C 1 alkyl-C 3-10  cycloalkyl, \u2014C 1 alkyl-3-7 membered heterocyclyl or \u2014C 1 alkyl-heteroaryl,\n wherein the C 3-10 cycloalkyl or 3-7 membered heterocyclyl is optionally fused to aryl, heteroaryl, C 3-7 cycloalkyl or 3-7 membered heterocyclyl; or \n wherein the C 3-10 cycloalkyl or 3-7 membered heterocyclyl is optionally substituted by =(spiro-C 3-7 cycloalkyl) or =(spiro-(3-7 membered heterocyclyl)); \n wherein R 1  is substituted by one, two, three, or four R a  groups independently selected from oxo, halogen, cyano, nitro, C 1-6 alkyl, \u2014C 1-6 haloalkyl, C 1-6 alkyl-cyano, \u2014OR, \u2014NR 2 , \u2014SR, \u2014C(O)OR, \u2014C(O)N(R) 2 , \u2014C(O)R, \u2014S(O)R, \u2014S(O)OR, \u2014S(O)N(R) 2 , \u2014S(O) 2 R, \u2014S(O) 2 OR, \u2014S(O) 2 N(R) 2 , \u2014OC(O)R, \u2014OC(O)OR, \u2014OC(O)N(R) 2 , \u2014N(R)C(O)R, \u2014N(R)C(O)OR, and \u2014N(R)C(O)N(R) 2 .

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.34783
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12666423', '15122863', '14061616', '16472185', '13897927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8185279135214916
- 35 USC 102 Novelty (BERT): 0.5346447912267048
- Combined Prediction Score: 0.7901396012920129
- Mean Citation Score: 367.118278
- Max Citation Score: 369.48654
- Similarity Product: 256.74806134293794

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test