PATENT CLAIM ANALYSIS

Application Number: 16183616
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["424", "400000"]

Abstract:
Novel drug carriers capable of targeted and/or pH dependent release of biologically active agents into selected pH environments including the gastrointestinal (GI), ophthalmic, urinary, or reproductive tracts. Unexpectedly, carriers including free fatty acids (FFA) are able to deliver biologically active agents to various pH environments. Such targeted delivery is tailorable and useful for active agents that are: (a) injurious to the upper GI tract (esophagus, stomach, and duodenum), (b) acid labile, (c) impermeable/soluble compounds in GI fluids, (d) susceptible to first pass metabolism, and/or (e) cause stomach irritation, upset, or dyspepsia.

Claim (Index 44):
The pharmaceutical composition of claim  41 , wherein:\n (a) the NSAID is released at pH values of less than pH 2 at a rate of less than about 20% in thirty minutes, and (b) the NSAID is released at pH values above about pH 3, at a rate of greater than about 80% in thirty minutes. 45 . The pharmaceutical composition of  claim 24 , wherein the amount of phospholipids is selected from the group consisting of about 0.5 wt. %, about 1 wt. %, about 2 wt. %, about 2.5 wt. %, and about 5 wt. %, and about 7.5 wt. %.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 98.0
- Lexical Diversity: 1.68493
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13631963', '15644694', '13908233', '13791189', '14495525']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8309290855806352
- 35 USC 102 Novelty (BERT): 0.6316857986339449
- Combined Prediction Score: 0.8110047568859662
- Mean Citation Score: 556.4023460000002
- Max Citation Score: 646.3022
- Similarity Product: 545.2057656721591

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test