PATENT CLAIM ANALYSIS

Application Number: 15962333
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "210180"]

Abstract:
The present invention relates to certain thiazolopyrimidinone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Claim (Index 2):
A compound of Formula (I): wherein R a  is C 1-6 alkyl optionally substituted with one or more R b  substituents; C 2-6 alkenyl; C 2-6 alkynyl; halo; \u2014C(O)R c ; \u2014NR d R e ; \u2014C(O)NR d R e ; \u2014C(S)NR d R e ; \u2014C(\u2550N\u2014OH)\u2014C 1-4 alkyl; \u2014SO 2 C 1-4 alkyl; cyano; C 3-6 cycloalkyl optionally substituted with one or more R f  substituents; or a phenyl, monocyclic heteroaryl, or heterocycloalkyl ring, each ring optionally substituted with one or more R g  substituents;\n wherein each R b  substituent is independently selected from the group consisting of \u2014OH, \u2014C 1-4 alkoxy, \u2014NR d R e , \u2014C(O)NR d R e , \u2014SC 1-4 alkyl, \u2014SO 2 C 1-4 alkyl, cyano, halo, and monocyclic heteroaryl; \n R c  is C 1-4 alkyl, \u2014C 1-4 haloalkyl, C 3-6 cycloalkyl, or a monocyclic, carbon-linked heterocycloalkyl; \n R d  is H or C 1-4 alkyl; \n R e  is H; C 1-4 alkyl optionally substituted with \u2014CN, \u2014CF 3 , \u2014OH, or a monocyclic heterocycloalkyl; C 3-6 cycloalkyl; \u2014OH; or \u2014OC 1-4 alkoxy; \n or R d  and R e  taken together with the nitrogen to which they are attached form a heterocycloalkyl, optionally substituted with C 1-4 alkyl or \u2014OH; \n each R f  substituent is independently selected from the group consisting of: C 1-4 alkyl optionally substituted with \u2014OH, cyano, or C 1-4 alkoxy; C 1-4 haloalkyl; \u2014CONH 2 ; and cyano; and \n each R g  substituent is independently selected from the group consisting of C 1-4 alkyl, \u2014CF 3 , halo, \u2014NH 2 , \u2014OCH 3 , cyano, and \u2014OH; \n R 1  is selected from the group consisting of H, C 1-6 alkyl, C 1-4 haloalkyl, and C 3-6 cycloalkyl; or R a  and R 1  taken together with the carbons to which they are attached form a 5- to 7-membered ring, optionally containing an O or NH, and optionally substituted with one or more R h  substituents;\n wherein each R h  substituent is independently \u2014C(O)NR i R j , cyano, or is C 1-4 alkyl optionally substituted with \u2014OH, \u2014OCH 3 , cyano, or \u2014C(O)NR i R j ; or two R h  groups attached to the same carbon and taken together with the carbon to which they are attached form a carbonyl or a C 3-6 cycloalkyl;\n wherein R i  and R j  are each independently H or C 1-4 alkyl; \n \n R 2  is \u2014R m , \u2014OR m , or \u2014NR m R n ;\n wherein R m  is aryl or heteroaryl, each optionally substituted with one or more R s  substituents;\n wherein each R s  substituent is independently selected from the group consisting of C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, C 1-4 alkyl-OH, C 1-4 haloalkoxy, halo, cyano, C 3-6 cycloalkyl, \u2014NHSO 2 C 1-4 alkyl, and \u2014SO 2 C 1-4 alkyl; \n \n R n  is H, C 1-4 haloalkyl, or C 1-4 alkyl optionally substituted with \u2014OH or C 1-4 alkoxy;\n or R m  and R n  taken together with the nitrogen to which they are attached form a pyrrolidine or piperidine ring, optionally substituted with C 1-4 alkyl and optionally fused to phenyl, wherein said phenyl is optionally substituted with halo; \n \n R 3  is H or methyl; and R 4  is H or fluoro; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 243.0
- Percentile: 91.0
- Lexical Diversity: 1.21053
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15094687', '16068559', '10038069', '14735924', '11179458']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8094547675055733
- 35 USC 102 Novelty (BERT): 0.5787585653209685
- Combined Prediction Score: 0.7863851472871128
- Mean Citation Score: 383.932908
- Max Citation Score: 457.0993
- Similarity Product: 436.6014516109825

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test