PATENT CLAIM ANALYSIS

Application Number: 15575778
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2018-10
Patent Classification: ["544", "293000"]

Abstract:
The present invention relates to an improved process for the preparation of N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyl amino)-(2E)-2-butenamide (2Z)-2-butenedioate (1:2) represented by the following structural formula:

Claim (Index 14):
A process for the preparation of crystalline form-N of 4-[(3-Chloro-4-fluorophenyl)amino]-6-amino-7-((S)tetrahydrofuran-3-yloxy)-quinazoline dihydrochloride compound of formula-8a, comprising of;\n a) Adding a suitable solvent or mixture of solvents to 4-[(3-chloro-4-fluoro phenyl)amino]-6-amino-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline dihydrochloride compound of formula-8a, b) stirring the reaction mixture at a suitable temperature, c) heating the reaction mixture to a suitable temperature, d) cooling the reaction mixture to a suitable temperature, e) filtering the solid, washing with a suitable solvent and then drying to get crystalline form-N of 4-[(3-Chloro-4-fluorophenyl)amino]-6-amino-7-((S)tetrahydrofuran-3-yloxy)-quinazoline dihydrochloride compound of formula-8a.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 97.0
- Lexical Diversity: 1.46154
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15516382', '15565996', '15553843', '13138429', '11997719']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5260041898868374
- 35 USC 102 Novelty (BERT): 0.5257383269499295
- Combined Prediction Score: 0.5259776035931466
- Mean Citation Score: 289.474582
- Max Citation Score: 317.6971
- Similarity Product: 226.23853350010512

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test