PATENT CLAIM ANALYSIS

Application Number: 15571475
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["514", "330000"]

Abstract:
Provided herein, inter alia, are methods and compounds for inhibiting K-Ras and for treating cancer.

Claim (Index 59):
The compound of  claim 54 , or a pharmaceutically acceptable salt thereof, wherein:\n each R 1  is independently halogen, \u2014CX 1 3 , \u2014CHX 1 2 , \u2014CH 2 X 1 , \u2014CN, \u2014SO v1 NR 7 R 8 , \u2014NO 2 , \u2014NR 7 R 8 , \u2014C(O)R 9 , \u2014C(O)\u2014OR 9 , \u2014C(O)NR 7 R 8 , \u2014OR 10 , \u2014NR 7 C(O)R 9 , \u2014NR 7 C(O)OR 9 , \u2014OCX 1 3 , \u2014OCHX 1 2 , substituted or unsubstituted C 1 -C 8  alkyl, substituted or unsubstituted C 3 -C 8  cycloalkyl, substituted or unsubstituted 3 to 8 membered heterocycloalkyl, substituted or unsubstituted C 6 -C 10  aryl, or substituted or unsubstituted 5 to 10 membered heteroaryl; R 7  is hydrogen, C 1 -C 8  alkyl unsubstituted or substituted with R 48 , C 3 -C 8  cycloalkyl unsubstituted or substituted with R 48 , 3 to 8 membered heterocycloalkyl unsubstituted or substituted with R 48 , C 6 -C 10  aryl unsubstituted or substituted with R 48 , or 5 to 10 membered heteroaryl unsubstituted or substituted with R 48 , wherein R 48  is halogen, \u2014CX 48 3 , \u2014CHX 48 2 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHC(O)\u2014OH, \u2014OCX 48 3 , \u2014OCHX 48 2 , or \u2014OCH 2 X 48 , wherein X 48  is halogen; R 8  is hydrogen, C 1 -C 8  alkyl unsubstituted or substituted with R 51 , C 3 -C 8  cycloalkyl unsubstituted or substituted with R 51 , 3 to 8 membered heterocycloalkyl unsubstituted or substituted with R 51 , C 6 -C 10  aryl unsubstituted or substituted with R 51 , or 5 to 10 membered heteroaryl unsubstituted or substituted with R 51 , wherein R 51  is halogen, \u2014CX 51 3 , \u2014CHX 51 2 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHC(O)\u2014OH, \u2014OCX 51 3 , \u2014OCHX 51 2 , or \u2014OCH 2 X 51 , wherein X 51  is halogen; R 9  is hydrogen, C 1 -C 8  alkyl unsubstituted or substituted with R 54 , C 3 -C 8  cycloalkyl unsubstituted or substituted with R 54 , 3 to 8 membered heterocycloalkyl unsubstituted or substituted with R 54 , C 6 -C 10  aryl unsubstituted or substituted with R 54 , or 5 to 10 membered heteroaryl unsubstituted or substituted with R 54 , wherein R 54  is halogen, \u2014CX 54 3 , \u2014CHX 54 2 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHC(O)\u2014OH, \u2014OCX 54 3 , \u2014OCHX 54 2 , or \u2014OCH 2 X 54 , wherein X 54  is halogen; and R 10  is hydrogen, C 1 -C 8  alkyl unsubstituted or substituted with R 57 , C 3 -C 8  cycloalkyl unsubstituted or substituted with R 57 , 3 to 8 membered heterocycloalkyl unsubstituted or substituted with R 57 , C 6 -C 10  aryl unsubstituted or substituted with R 57 , or 5 to 10 membered heteroaryl unsubstituted or substituted with R 57 , wherein R 57  is halogen, \u2014CX 57 3 , \u2014CHX 57 2 , \u2014CN, \u2014OH, \u2014NH 2 , \u2014COOH, \u2014CONH 2 , \u2014NO 2 , \u2014SH, \u2014SO 3 H, \u2014SO 4 H, \u2014SO 2 NH 2 , \u2014NHC(O)\u2014OH, \u2014OCX 57 3 , \u2014OCHX 57 2 , or \u2014OCH 2 X 57 , wherein X 57  is halogen.

Metadata:
- Claim Count in Document: 68.0
- Percentile: 93.0
- Lexical Diversity: 1.2
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15382942', '15950953', '15757238', '15662861', '15700040']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8576526540472578
- 35 USC 102 Novelty (BERT): 0.6038581682999447
- Combined Prediction Score: 0.8322732054725265
- Mean Citation Score: 535.581868
- Max Citation Score: 593.351
- Similarity Product: 457.4571566324234

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test