PATENT CLAIM ANALYSIS

Application Number: 16235068
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["546", "085000"]

Abstract:
Provided herein are improved processes for the synthesis of substituted tetrahydro beta-carboline derivatives. In particular, provided herein are improved processes useful for the preparation of (S)-4-chlorophenyl 6-chloro-1-(4-methoxyphenyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate. Formula (I):

Claim (Index 32):
The process of  claim 30 , further comprising the step of preparing a compound of Formula (V) by reacting a compound of Formula (VII): with a compound of Formula (VI): in the presence of a suitable acid in a suitable solvent, wherein\n X is halogen, \n R is substituted or unsubstituted C 1  to C 8  alkyl, and \n HB\u2032 is an acid suitable to form a salt with the amino group of a compound of Formula (VII); and \n wherein the suitable acid is hydrochloric acid, the suitable solvent is selected from water or EtOAc and HB\u2032 is selected from hydrochloric acid or acetic acid.

Metadata:
- Claim Count in Document: 42.0
- Percentile: 98.0
- Lexical Diversity: 1.38889
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13541504', '13806378', '13940421', '15807877', '12578934']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7416297392955115
- 35 USC 102 Novelty (BERT): 0.4749923740930544
- Combined Prediction Score: 0.7149660027752657
- Mean Citation Score: 197.166682
- Max Citation Score: 206.0179
- Similarity Product: 166.9040197066724

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test