PATENT CLAIM ANALYSIS

Application Number: 15747874
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "001610"]

Abstract:
The present invention relates to combinations of at least two components, component A and component B, component A being an immune checkpoint inhibitor, and component B being a pharmaceutically acceptable salt of the alkaline-earth radio nuclide radium-223, the combination being useful for the treatment or prophylaxis of cancer.

Claim (Index 13):
A kit comprising:\n a combination of: component A: one or more immune checkpoint inhibitors is selected from the group consisting of: a biologic therapeutic, a small molecule, a monoclonal antibody, a humanized antibody, a fully human antibody, a fusion protein, anti-CTLA-4 antibody, a PD-1 blocker, an anti-PD1 antibody, an anti-PD-L1 antibody, a LAG-3 inhibitor, B7-H3 inhibitor, a TIM3 inhibitor, and a combination thereof; component B: a suitable pharmaceutically acceptable salt of the alkaline-earth radionuclide radium-223 or a solvate or a hydrate thereof; and, optionally, component C: one or more further pharmaceutical agents; in which optionally either or both of said components A and B in any of the above-mentioned combinations are in the form of a pharmaceutical formulation/composition which is ready for use to be administered simultaneously, concurrently, separately or sequentially.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.39474
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15101540', '15101638', '15506316', '15490535', '15115730']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6514512859423304
- 35 USC 102 Novelty (BERT): 0.5113668370804426
- Combined Prediction Score: 0.6374428410561416
- Mean Citation Score: 250.10738
- Max Citation Score: 284.9628600000001
- Similarity Product: 227.7339945460833

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test