PATENT CLAIM ANALYSIS

Application Number: 16130295
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-02
Patent Classification: ["800", "278000"]

Abstract:
Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell. The methods and compositions employ a guide RNA/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a plant, plant cell or seed. Also provided are compositions and methods employing a guide polynucleotide/Cas endonuclease system for genome modification of a nucleotide sequence in the genome of a cell or organism, for gene editing, and/or for inserting or deleting a polynucleotide of interest into or from the genome of a cell or organism. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Breeding methods and methods for selecting plants utilizing a two component RNA guide and Cas endonuclease system are also disclosed. Compositions and methods are also provided for editing a nucleotide sequence in the genome of a cell.

Claim (Index 67):
A method for modifying a target site in the genome of a maize cell, the method comprising:\n a) providing to the maize cell a guide RNA and a Cas9 endonuclease, wherein said guide RNA and Cas9 endonuclease form a complex that enables the Cas9 endonuclease to introduce a double strand break at the target site; and, b) identifying at least one maize cell that has a modification of the target site, wherein the modification is selected from the group consisting of: at least one nucleotide insertion, at least one nucleotide deletion, at least one nucleotide substitution, and any combination of the preceding.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 97.0
- Lexical Diversity: 2.37333
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15325116', '14913630', '15503383', '15138604', '15803424']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.3719265198871893
- 35 USC 102 Novelty (BERT): 0.6041899686221768
- Combined Prediction Score: 0.395152864760688
- Mean Citation Score: 504.33485200000007
- Max Citation Score: 635.41016
- Similarity Product: 470.25351734361647

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test