PATENT CLAIM ANALYSIS

Application Number: 15984935
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["435", "006140"]

Abstract:
The present invention is directed to methods for detecting a melanoma, methods for determining whether a melanoma is stable or progressive, methods for evaluating the extent of surgery resection in a subject having a melanoma, and methods for determining a response by a subject having a melanoma to a therapy.

Claim (Index 30):
A method for determining a response by a subject having a melanoma to a therapy, comprising:\n determining a first expression level of at least 28 biomarkers from a first test sample from the subject at a first time point by contacting the first test sample with a plurality of agents specific to detect the expression of the at least 28 biomarkers, wherein the 28 biomarkers comprise ATL1, ATP6V0D, C1ORF21, CFLAR, CFLAR-AS1, CHP1, DDX55, DMD, DNAJC9, ENOSF1, FANCL, HJURP, HLA-DOA, HLA-DRA, HNRNPA3P1, IL23A, IQGAP1, LOC494127, LOC646471, LOH12CR, PBXIP1, RNF5, SERTAD2, SLC35G5, SPATS2L, TDRD7, TXK, and YY2; determining a second expression level of the at least 28 biomarkers from a second test sample from the subject at a second time point by contacting the second test sample with a plurality of agents specific to detect the expression of the at least 28 biomarkers, wherein the second time point is after the first time point and after the administration of the therapy to the subject; comparing the first expression level with the second expression level; and producing a report, wherein the report identifies that the subject is responsive to the therapy when the second expression level is significantly decreased as compared to the first expression level.

Metadata:
- Claim Count in Document: 46.0
- Percentile: 93.0
- Lexical Diversity: 1.74194
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14855229', '14357191', '14405739', '14433681', '13580571']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4989699607379757
- 35 USC 102 Novelty (BERT): 0.4986605726071566
- Combined Prediction Score: 0.4989390219248938
- Mean Citation Score: 157.20472
- Max Citation Score: 170.31271
- Similarity Product: 104.517301708318

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test