PATENT CLAIM ANALYSIS

Application Number: 15777290
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["424", "186100"]

Abstract:
The invention provides lentiviral preparations containing a sulfonic acid buffer, such as 1,4-piperazinediethanesulfonic acid (PIPES), 2-(N-morpholino)ethanesulfonic acid (MES), and 3-morpholinopropane-1-sulfonic acid (MOPS), a sodium citrate buffer, or a phosphate buffer. The invention additionally encompasses methods of lentiviral purification as well as methods of transducing human cells.

Claim (Index 54):
A method of purifying a lentiviral vector, said method comprising passing the aqueous composition of  claim 1  through a filter or a material comprising a plurality of particles, or contacting the aqueous composition with a nuclease, thereby producing an aqueous composition that is substantially free of microorganisms.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 93.0
- Lexical Diversity: 1.65789
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15106862', '12443153', '15022049', '13277900', '14412844']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7159324803754683
- 35 USC 102 Novelty (BERT): 0.5083887623326847
- Combined Prediction Score: 0.6951781085711899
- Mean Citation Score: 254.641716
- Max Citation Score: 258.30765
- Similarity Product: 164.4986232503146

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test