PATENT CLAIM ANALYSIS

Application Number: 16030253
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "044000"]

Abstract:
This invention relates to compounds, compositions, and methods useful for reducing β-catenin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.

Claim (Index 3):
The dsNA of  claim 2 , wherein the dsNA comprises one or more modifications selected from a 2\u2032-O-methyl nucleotide, a 2\u2032-methoxyethoxy nucleotide, a 2\u2032-fluoro nucleotide, a 2\u2032-allyl nucleotide, a 2\u2032-O-[2-(methylamino)-2-oxoethyl] nucleotide, a 4\u2032-thio nucleotide, a 4\u2032-CH2-O-2\u2032-bridge, a 4\u2032-(CH2)2-O-2\u2032-bridge, a locked nucleic acid (LNA), a 2\u2032-amino, a 2\u2032-O\u2014(N-methlycarbamate), a 2\u2032-O-alkyl ribonucleotide, a deoxyribonucleotide, a dideoxyribonucleotide, an acyclonucleotide, a 3\u2032-deoxyadenosine (cordycepin), a 3\u2032-azido-3\u2032-deoxythymidine (AZT), a 2\u2032,3\u2032-dideoxyinosine (ddI), a 2\u2032,3\u2032-dideoxy-3\u2032-thiacytidine (3TC), a 2\u2032,3\u2032-didehydro-2\u2032,3\u2032-dideoxythymidine (d4T), a monophosphate nucleotide of 3\u2032-azido-3\u2032-deoxythymidine (AZT), a 2\u2032,3\u2032-dideoxy-3\u2032-thiacytidine (3TC) and a monophosphate nucleotide of 2\u2032,3\u2032-didehydro-2\u2032,3\u2032-dideoxythymidine (d4T), a 4-thiouracil, a 5-bromouracil, a 5-iodouracil, a 5-(3-aminoallyl)-uracil, a phosphonate backbone modification, a phosphorothioate backbone modification and a phosphotriesterphosphate backbone modification.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 95.0
- Lexical Diversity: 1.13333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15064376', '13718525', '14925952', '14300754', '14543257']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8937049732396632
- 35 USC 102 Novelty (BERT): 0.6994786984701248
- Combined Prediction Score: 0.8742823457627095
- Mean Citation Score: 747.1398780000003
- Max Citation Score: 795.2667
- Similarity Product: 717.499463225627

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test