PATENT CLAIM ANALYSIS

Application Number: 16079162
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "233800"]

Abstract:
The invention relates to acid addition salts of piperazine derivatives, as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and, in particular, as glycosidase inhibitors.

Claim (Index 15):
An acid addition salt of hydrochloric acid, maleic acid, tartaric acid, sulfuric acid or p-toluolsulfonic acid with compounds of formula I wherein:\n X denotes O or CH 2 ; \n n denotes 0 or 1; and \n Q denotes one of the following groups: \n Z 1  is S, O, NR 3 ; Z 2 , Z 2\u2032 , Z 3  independently denote CR 5 , CR 6  or N; R 5 , R 5\u2032 , R 6 , R 7  independently denote H, Hal, NR 3 R 4 , NO 2 , straight chain or branched alkyl having 1 to 12 carbon atoms, wherein 1 to 3 CH 2 -groups may be replaced by a group selected from O, NR 3 , S, SO, SO 2 , CO, COO, OCO, CONR 3 , NR 3 CO and wherein 1 to 5 hydrogen atoms may be replaced by Hal, NR 3 R 4 , NO 2 , OR 3 , Het, Ar, Cyc, or denote Ar, Het or Cyc; R 8  denotes H, methyl or straight chain or branched alkyl having 2 to 12 carbon atoms, wherein 1 to 3 CH 2 -groups may be replaced by a group selected from O, NR 3 , S, SO, SO 2 , CO, COO, OCO, CONR 3 , NR 3 CO and wherein 1 to 5 hydrogen atoms may be replaced by Hal, NR 3 R 4  or NO 2 ; R 3 , R 4  denote each independently H or a straight chain or branched alkyl group having 1 to 12 carbon atoms; Hal denotes F, Cl, Br or I; Het denotes a saturated, unsaturated or aromatic ring, being monocyclic or bicyclic or fused-bicyclic and having 3- to 8-members and containing 1 to 4 heteroatoms selected from N, O and S, which may be substituted by 1 to 3 substituents selected from R 5 , Hal and OR 3 ; Ar denotes a 6-membered carbocyclic aromatic ring or a fused or non-fused bicyclic aromatic ring system, which is optionally substituted by 1 to 3 substituents independently selected from R 5 , OR 3  and Hal; Cyc denotes a saturated or an unsaturated carbocyclic ring having from 3 to 8 carbon atoms which is optionally substituted by 1 to 3 substituents independently selected from R 5  or Hal or OH; as well as solid forms thereof.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 96.0
- Lexical Diversity: 1.34483
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15830675', '16078715', '15507375', '14502213', '15539147']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7556943026035781
- 35 USC 102 Novelty (BERT): 0.5299396628212518
- Combined Prediction Score: 0.7331188386253454
- Mean Citation Score: 296.0521720000001
- Max Citation Score: 318.7650799999999
- Similarity Product: 217.7743372410773

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test