PATENT CLAIM ANALYSIS

Application Number: 15754649
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "293000"]

Abstract:
The present disclosure pertains to a pharmaceutical combination comprising (a) alpha-isoform specific PI3K inhibitor and (b) an AKT inhibitor; combined preparations and pharmaceutical compositions thereof; the uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject in need thereof comprising administering a therapeutically effective amount of such combination.

Claim (Index 39):
The method according to  claim 37 , wherein the cancer is selected from the group consisting of a benign or malignant tumor of the lung (including small cell lung cancer and non-small-cell lung cancer), bronchus, prostate, breast (including sporadic breast cancers and sufferers of Cowden disease), pancreas, gastrointestinal tract, colon, rectum, colon carcinoma, colorectal, thyroid, liver, biliary tract, intrahepatic bile duct, hepatocellular, adrenal gland, stomach, gastric, glioma, glioblastoma, neuroblastoma, medulloblastoma, endometrial, kidney, renal pelvis, bladder, uterus, cervix, vagina, ovary, testicle, multiple myeloma, esophagus, neck or head, brain, oral cavity and pharynx, larynx, small intestine, bone, a melanoma, villous colon adenoma, a sarcoma (including Ewing's sarcoma, Rhabdomyosarcoma, osteosarcoma), a neoplasia, a neoplasia of epithelial character, a mammary carcinoma, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, polycythemia vera, essential thrombocythemia, a leukemia (including acute myelogenous leukemia, chronic myelogenous leukemia, lymphocytic leukemia, and myeloid leukemia), a lymphoma (including non-Hodgkin lymphoma and Hodgkin's lymphoma), myelofibrosis with myeloid metaplasia, Waldenstroem disease, Bannayan-Zonana syndrome, Lhermitte-Duclos disease, Wilm's tumor, mesothelioma, salivary gland, and GIST (gastrointestinal stromal tumor).

Metadata:
- Claim Count in Document: 11.0
- Percentile: 88.0
- Lexical Diversity: 1.55814
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15755140', '15755122', '14240499', '13799076', '14419256']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7995360913902652
- 35 USC 102 Novelty (BERT): 0.5397887033634866
- Combined Prediction Score: 0.7735613525875873
- Mean Citation Score: 326.0346760000001
- Max Citation Score: 369.83292
- Similarity Product: 234.22984969937323

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test