PATENT CLAIM ANALYSIS

Application Number: 15777223
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "030000"]

Abstract:
The invention provides novel compounds that are derivatives of Azithromycin and that have been found by the current inventors to have low antimicrobial activity but significant epithelial barrier enhancement properties. The invention further provides use of the compounds as a medicament, in particular in the treatment or prophylaxis of a disease or condition that is caused by a defect in epithelial cells or tissue, or a disease or condition that benefits from enhancement or restoration of epithelial barrier function, for example diseases of the respiratory tract.

Claim (Index 22):
The compound according to  claim 18 , wherein\n R 2  is according to formula (III) wherein R 7  is C 1-6 -alkyl; and R 8  is selected from the group consisting of C 6-14 -arylcarbonyl optionally substituted with 1 to 5 groups selected from C 1-3 -alkyl sulfonyl groups and/or C 1-3 -alkyl groups; HOOC\u2014(CH 2 ) m \u2014(CO)\u2014 with m being from 0 to 6, a substituent of formula (V.1) with Ar being C 6-14 -aryl and n, p and q being independently from 0 to 6; R 3  is H; and R 4  and R 5  are both H; or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.625
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14902129', '10421577', '10218154', '10840529', '09485292']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8474165734165626
- 35 USC 102 Novelty (BERT): 0.549186856542567
- Combined Prediction Score: 0.8175936017291631
- Mean Citation Score: 400.387328
- Max Citation Score: 434.61444000000006
- Similarity Product: 306.838403512044

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test