PATENT CLAIM ANALYSIS

Application Number: 15994074
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "186100"]

Abstract:
Methods of producing a pathogen with reduced replicative fitness are disclosed, as are attenuated pathogens produced using the methods. In particular examples, the method includes deoptimizing one or more codons in a coding sequence, thereby reducing the replicative fitness of the pathogen. Methods of using the attenuated pathogens as immunogenic compositions are also disclosed.

Claim (Index 20):
A method of eliciting an immune response against a virus in a subject, comprising administering to the subject a immunologically effective amount of the modified virus of  claim 1 , thereby eliciting an immune response in the subject.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 93.0
- Lexical Diversity: 1.57895
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11576941', '12594173', '14766620', '15315687', '15508695']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6783894083773194
- 35 USC 102 Novelty (BERT): 0.727930844826199
- Combined Prediction Score: 0.6833435520222074
- Mean Citation Score: 435.261758
- Max Citation Score: 906.7351
- Similarity Product: 766.5914473298428

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test