PATENT CLAIM ANALYSIS

Application Number: 15768736
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["435", "288400"]

Abstract:
The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

Claim (Index 49):
The method of  claim 43 , wherein said brain microvascular endothelial cells are derived from induced pluripotent stem cells from a patient diagnosed with MCT8-specific thyroid hormone cell-membrane transporter deficiency.

Metadata:
- Claim Count in Document: 206.0
- Percentile: 91.0
- Lexical Diversity: 1.35556
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13793466', '13155435', '13218123', '15478463', '13679510']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6373481954425441
- 35 USC 102 Novelty (BERT): 0.527532855970488
- Combined Prediction Score: 0.6263666614953385
- Mean Citation Score: 299.6343080000001
- Max Citation Score: 346.11197000000016
- Similarity Product: 216.4692178093303

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test