PATENT CLAIM ANALYSIS

Application Number: 16214455
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["435", "007920"]

Abstract:
The invention relates to an anti-human p53 antibody suitable for specifically binding a linear epitope which is exposed only in a conformationally altered isoform of the characteristic p53 protein of patients with Alzheimer's disease or prone to develop Alzheimer's disease or cognitive impairment during ageing. Methods and diagnostic and prognostic kits are also described.

Claim (Index 15):
An in vitro method of detecting an isoform of the human p53 protein in a sample, said isoform being conformationally altered by post-translational modification with respect to the wild-type human p53 protein, the method comprising the steps of:\n contacting the sample with at least one antibody according to  claim 12 ; and detecting the formation of an immunocomplex between the human p53 protein and the antibody in the sample.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.20833
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15515693', '15342629', '15599685', '08466554', '13363214']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4955572845200036
- 35 USC 102 Novelty (BERT): 0.5301353795841844
- Combined Prediction Score: 0.4990150940264217
- Mean Citation Score: 228.56466
- Max Citation Score: 340.3119
- Similarity Product: 246.616438822782

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test