PATENT CLAIM ANALYSIS

Application Number: 15769754
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["514", "210160"]

Abstract:
The present invention relates to oxa-diazaspiro compounds having pharmacological activity towards the sigma (σ) receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

Claim (Index 33):
A process for the preparation of the compound according to  claim 18 , wherein R 1  is \u2014(CR 4 R 4\u2032 ) p R 1\u2032 , Y represents CO and R 3  and R 3\u2032 , together with the carbon atom to which they are attached, form a cyclopropyl (compounds of formula Id), which process comprises a) the treatment with a strong base of a compound of formula Ic wherein R s \u2550R s\u2032 \u2550H and s=1 wherein LG represents a leaving group, including halogen, mesylate, tosylate and triflate, or b) a cyclopropanation reaction on a compound of formula XXXI or c) the alkylation of a compound of formula XXV with a compound of formula XV wherein the compound of formula XV is an alkylating agent and V is a leaving group; or d) the reaction of a compound of formula XIXH with a compound of formula IX, X or XI, wherein LG is a leaving group, including halogen, mesylate, tosylate and triflate, and wherein R 1\u2032 , R 2 , R 4 , R 4\u2032 , R 5 , R 5\u2032 , R 6 , R 6\u2032 , R 7 , R 8 , R 9 , R 10 , R x , R x\u2032 , X, m, n, p, q and r have the meanings as defined in  claim 18  for the compound of Formula (I).

Metadata:
- Claim Count in Document: 29.0
- Percentile: 91.0
- Lexical Diversity: 1.30556
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15769502', '15769520', '15315486', '15315095', '15569939']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8122116444168536
- 35 USC 102 Novelty (BERT): 0.5683333521126572
- Combined Prediction Score: 0.787823815186434
- Mean Citation Score: 443.37464400000016
- Max Citation Score: 477.3474
- Similarity Product: 326.9519857769966

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test