PATENT CLAIM ANALYSIS

Application Number: 16215137
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-08
Patent Classification: ["424", "450000"]

Abstract:
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.

Claim (Index 133):
The isolated AARS polypeptide of  claim 131 , further comprising an element selected from the group consisting of:\n (i) a binding partner that binds to the AARS polypeptide; (ii) an engineered population of cells in which at least one cell comprises a polynucleotide encoding said AARS polypeptide, wherein the cells are capable of growing in a serum-free medium; (iii) a cell that comprises a cell-surface receptor or an extracellular portion thereof that binds to the polypeptide, and a molecule of less than about 2000 daltons, or a second polypeptide, which modulates binding or interaction of the AARS polypeptide and the extracellular receptor; (iv) a cell that comprises a cell-surface receptor or an extracellular portion thereof that specifically binds to the AARS polypeptide, wherein the cell comprises an indicator molecule that allows detection of a change in the levels or activity of the cell-surface receptor or extracellular portion thereof; and (v) an engineered population of cells in which at least one cell comprises a polynucleotide encoding said AARS polypeptide, at least about 10 liters of a serum-free growth medium, and a sterile container.

Metadata:
- Claim Count in Document: 51.0
- Percentile: 98.0
- Lexical Diversity: 1.29032
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16171087', '13809754', '13809750', '15459875', '14675343']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7392257984178583
- 35 USC 102 Novelty (BERT): 0.5414286486832918
- Combined Prediction Score: 0.7194460834444016
- Mean Citation Score: 359.228898
- Max Citation Score: 400.5334
- Similarity Product: 300.98729406797884

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test