PATENT CLAIM ANALYSIS

Application Number: 15755484
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-02
Patent Classification: ["514", "261100"]

Abstract:
Pharmaceutical compounds, compositions, methods, and uses therefor are presented using selected triazolopyridines and triazolopyrimidines to inhibit or reduce phosphorylation of tau proteins or that act as antagonists of corticotropin-releasing factor. Viewed from another perspective, compounds, compositions, and methods are presented for treating or preventing symptoms of Alzheimer's disease by inhibiting or reducing the phosphorylation of tau proteins.

Claim (Index 31):
The pharmaceutical composition of  claim 30 , wherein the second pharmaceutical agent is selected from the group consisting of disulfiram, honokiol, nimetazepam, a tropinol-ester, a TrkA kinase inhibitor, a hydantoin, a D2 receptor agonist, an alphal-adrenergic receptor antagonist, an APP-specific BACE inhibitor, galangin, a galangin prodrug, rutin, a rutin prodrug, an acetylcholinesterase inhibitor, (\u2212) phenserine, tacrine, ipidacrine, galantamine, donepezil, icopezil, zanapezil, rivastigmine, huperzine A, phenserine, physostigmine, neostigmine, pyridostigmine, ambenonium, demarcarium, edrophonium, ladostigil, ungeremine, a NMDA receptor antagonist, memantine, a muscarinic receptor agonist, talsaclidine, AF-102B, AF-267B (NGX-267), a nicotinic receptor agonist, ispronicline (AZD-3480), a beta secretase inhibitor, a thiazolidinedione, rosiglitazone, pioglitazone, a gamma-secretase inhibitor, semagacestat (LY-450139), MK-0752, E-2012, BMS-708163, PF-3084014, begacestat (GSI-953), NIC5-15, an inhibitor of A\u03b2 aggregation, clioquinol (PBTI), PBT2, tramiprosate (homotaurine), scylla-inositol, bapineuzemab, epigallocatechin-3-gallate, an anti-inflammatory agent, a cyclooxygenase II inhibitor, an anti-oxidant, vitamin E, or a ginkolide.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15548402', '13899985', '11873941', '12402910', '14009654']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8099636465471184
- 35 USC 102 Novelty (BERT): 0.5175365469648314
- Combined Prediction Score: 0.7807209365888897
- Mean Citation Score: 204.896344
- Max Citation Score: 296.67456
- Similarity Product: 184.66553788055413

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test