PATENT CLAIM ANALYSIS

Application Number: 16314753
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["540", "469000"]

Abstract:
Mitochondria-targeting potassium sensors and method(s) for making such sensors. The sensor shows a response to potassium and displays a 130-fold dynamic range of fluorescence intensity and high brightness. The sensors response to potassium concentrations was demonstrated to be unaffected by cellular pH value and/or concentrations of other ions. The sensors can be used for monitoring the mitochondrial potassium efflux/influx.

Claim (Index 18):
The compound of  claim 16 , wherein the fluorescence intensity of said compound increases 1.3 fold at a wavelength of light of about 572 nm when said compound is exposed to a concentration of potassium at about 5 mM, and increases 57 fold at a wavelength of light of about 572 nm when said compound is exposed to a concentration of potassium at about 150 mM.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 99.0
- Lexical Diversity: 1.46667
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13985260', '13980946', '14118053', '15755175', '14783456']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6893121217973506
- 35 USC 102 Novelty (BERT): 0.5255260967113388
- Combined Prediction Score: 0.6729335192887493
- Mean Citation Score: 225.40770000000003
- Max Citation Score: 253.38112
- Similarity Product: 130.91774298217774

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test