PATENT CLAIM ANALYSIS

Application Number: 15975854
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["548", "469000"]

Abstract:
The present application, among other things, provides compounds that are capable of inhibiting the activity of anti-apoptotic Bcl-2 family proteins, for example, myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides pharmaceutical compositions as well as methods for using provided compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein. In some embodiments, a provided compound has the structure of formula I. In some embodiments, a provided compound has the structure of formula II.

Claim (Index 3):
The compound of  claim 1 , wherein R 7  is halo, \u2014CN, \u2014NO 2 , \u2014C(O)OR, \u2014OCF 3 , \u2014OR, \u2014SR, \u2014S(O) 2 OR, \u2014P(O)(OH) 2 , \u2014C(O)N(R) 2 , \u2014N(R) 2 , \u2014S(O) 2 N(R) 2 , \u2014NRS(O) 2 CF 3 , \u2014C(O)NRS(O) 2 R, \u2014S(O) 2 NRC(O)OR, \u2014S(O) 2 NRC(O)N(R) 2 , \u2014C(O)R, \u2014C(O)NRS(O) 2 CF 3 , \u2014NRC(O)R, \u2014OC(O)R, \u2014OC(O)N(R) 2 , \u2014C(NR)N(R) 2 , \u2014NRC(NR)N(R) 2 , \u2014S(O)R, \u2014S(O) 2 R, \u2014NRC(O)OR, or \u2014NRS(O) 2 R, or an optionally substituted group selected from C 1-6  alkyl, C 1-6  alkynyl or a ring selected from a 3-8 membered saturated or partially unsaturated carbocyclic ring, phenyl, a 3-8 membered saturated or partially unsaturated heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, an 8-14 membered bicyclic or polycyclic saturated, partially unsaturated or aryl ring, a 7-14 membered bicyclic or polycyclic saturated or partially unsaturated heterocyclic ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-14 membered bicyclic or polycyclic heteroaryl ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 93.0
- Lexical Diversity: 1.63333
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14914307', '14885181', '15129042', '14429799', '14966821']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7875895826371467
- 35 USC 102 Novelty (BERT): 0.5716389958668366
- Combined Prediction Score: 0.7659945239601157
- Mean Citation Score: 388.026742
- Max Citation Score: 480.23093
- Similarity Product: 389.5346600740362

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test