PATENT CLAIM ANALYSIS

Application Number: 16149025
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-03
Patent Classification: ["435", "188000"]

Abstract:
The present disclosure provides systems and methods for increasing production of an alkaloid product through the epimerization of a (S)-1-benzylisoquinoline alkaloid to a (R)-1-benyzlisoquinoline alkaloid via an engineered epimerase in an engineered host cell. A (S)-1-benzylisoquinoline alkaloid is contacted with said engineered epimerase. Contacting said (S)-1-benzylisoquinoline alkaloid with said engineered epimerase converts said (S)-1-benzylisoquinoline alkaloid to said (R)-1-benzylisoquinoline alkaloid.

Claim (Index 9):
The method of  claim 7 , wherein said oxidase component comprises a sequence that is encoded by a DNA sequence which comprises one or more mutations, each mutation at a codon position which corresponds to a position selected from the group consisting of positions 16, 17, 37, 50, 64, 69, 70, 110, 128, 155, 232, 234, 244, 293, 303, 328, 354, 387, 393, 427, and 477 within SEQ ID NO. 17.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 97.0
- Lexical Diversity: 2.05128
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15031618', '14211611', '15360763', '14614484', '14961662']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6660137673286675
- 35 USC 102 Novelty (BERT): 0.5277488535078472
- Combined Prediction Score: 0.6521872759465854
- Mean Citation Score: 346.805698
- Max Citation Score: 403.10944
- Similarity Product: 300.97723452964783

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test