PATENT CLAIM ANALYSIS

Application Number: 16142969
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["514", "220000"]

Abstract:
The invention comprises methods of modulating the complement cascade in a mammal and for treating and/or preventing diseases and disorders associated with the complement pathway by administering a compound of Formula I or Formula II, such as, for example, 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one or a pharmaceutically acceptable salt thereof.

Claim (Index 19):
A method for modulating the complement system in a subject in need thereof comprising administering a therapeutically effective amount of at least one compound of Formula II or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein: or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein: R A  and R B  are independently selected from hydrogen, methyl, \u2014(CH 2 ) n R F , \u2014(CH 2 ) n OR F , and \u2014CH 2 C(O)OR G ; n is selected from 1,2,3, and 4; R F  is selected from methyl, ethyl, and \u2014CH 2 CH 2 OCH 3 ; R G  is selected from methyl, Ethyl, n-propyl, isopropyl, n-butyl, and tert-butyl; R C  is selected from hydrogen, para-halogen, and \u2014OCH 2 O\u2014 or \u2014OCH 2 CH 2 O\u2014 connected to the ortho and meta positions or connected to the meta and para positions of the phenyl ring; and R D  and R E  are independently selected from hydrogen and methyl.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 97.0
- Lexical Diversity: 1.31915
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15066513', '11670238', '14513281', '13257082', '13265060']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6891878266943114
- 35 USC 102 Novelty (BERT): 0.6292075623735235
- Combined Prediction Score: 0.6831898002622327
- Mean Citation Score: 395.297994
- Max Citation Score: 685.7202
- Similarity Product: 497.9580639901399

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test