PATENT CLAIM ANALYSIS

Application Number: 16066600
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["424", "001650"]

Abstract:
The present invention provides a method for the purification of  227 Th from a mixture comprising  227 Th and  223 Ra, said method comprising: i) preparing a first solution comprising a mixture of  227 Th and  223 Ra ions dissolved in an aqueous solution of first mineral acid; ii) loading said first solution onto a strong base anion exchange resin; iii) eluting  223 Ra from said strong base anion exchange resin using a second mineral acid in an aqueous solution; iv) optionally rinsing said strong base anion exchange resin using a first aqueous medium; v) eluting  227 Th from said strong base anion exchange resin using a third mineral acid in an aqueous solution whereby to generate a second solution comprising  227 Th. The invention further provides a purified  227 Th solution, a corresponding pharmaceutical formulation and methods of treatment of neoplastic disease.

Claim (Index 19):
The method of  claim 18  wherein said radiopharmaceutical comprises a targeting conjugate formed from a targeting moiety linked to a complexing agent by a covalent linker.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 94.0
- Lexical Diversity: 2.41538
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13695353', '13695355', '14912312', '14400026', '15629409']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7509148451726037
- 35 USC 102 Novelty (BERT): 0.5435546413102629
- Combined Prediction Score: 0.7301788247863696
- Mean Citation Score: 279.83917599999995
- Max Citation Score: 405.08737
- Similarity Product: 257.9911429640842

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test