PATENT CLAIM ANALYSIS

Application Number: 15768468
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "513000"]

Abstract:
The present invention relates to a combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof, in particular the S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, and more particularly the 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate, and a compound able to increase H 2 O 2  level in cancer cells of a subject, in particular for use for the treatment of cancer in a subject, wherein cancer cells of said subject do not overproduce H 2 O 2  in comparison to a control value and have a level of GSH below 5 nmol for 25000 cells.

Claim (Index 12):
The pharmaceutical composition according to  claim 6 , wherein the cancer is chosen from leukemia, lymphomas, blood cancer, breast cancer (in particular TNBC), lung cancer (in particular EGFR mutated), melanomas, colon cancer, pancreas cancer, ovarian cancer, osteosarcoma, brain cancer, bladder cancer and gastric cancer.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.79032
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13546713', '15495670', '15120476', '15778213', '12981233']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.755894837633296
- 35 USC 102 Novelty (BERT): 0.4989505997699578
- Combined Prediction Score: 0.7302004138469622
- Mean Citation Score: 191.747058
- Max Citation Score: 199.93008
- Similarity Product: 128.62129996805194

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test