PATENT CLAIM ANALYSIS

Application Number: 15941735
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["424", "489000"]

Abstract:
The object of the present invention is an injectable sterile aqueous formulation, ready-to-use, resorbable, used for aesthetic purposes as a particulate, cohesive, viscoelastic gel comprising i) crosslinked hyaluronic acid, or one of its salts, at a concentration of between 0.1% and 4% (mass/volume); the crosslinking carried out providing the possibility of obtaining a gel based on crosslinked hyaluronic acid with a so-called cohesive structure, and ii) hydroxyapatite, at a concentration of between more than 70% and 140% (mass/volume), said hydroxyapatite being in the form of particles with an average size of less than or equal to 200 μm; said injectable sterile aqueous formulation having viscoelastic properties such that tan δ at the frequency of 1 Hz is less than or equal to 0.60.

Claim (Index 19):
A method for making an injectable sterile aqueous formulation according to  claim 1  comprising the steps:\n a) preparing a first mixture comprising crosslinked hyaluronic acid, or a salt thereof, by forming covalent bonds between the chains of the hyaluronic acid using bi- or poly-functional molecules to provide a crosslinked hyaluronic acid with a cohesive structure, \n b) purifying the first mixture, \n c) adding hydroxyapatite to the purified first mixture from step b) and dispersing the hydroxyapatite homogeneously in the purified first mixture comprising crosslinked hyaluronic acid to form a gel product, \n d) converting the gel product obtained in step c) into a ready-to-use form, and \n e) sterilizing the gel product in a ready-to-use form in humid heat.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 1.71765
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15913086', '15356885', '14896504', '15129876', '15526460']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7122769466899365
- 35 USC 102 Novelty (BERT): 0.572310581072845
- Combined Prediction Score: 0.6982803101282273
- Mean Citation Score: 339.225178
- Max Citation Score: 457.2731
- Similarity Product: 385.96165537488463

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test