PATENT CLAIM ANALYSIS

Application Number: 15744198
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["435", "007100"]

Abstract:
Platform technology involving aqueous microdroplet reaction vessels created, arrayed, and characterized by imaging microscopy in a microfluidic device are applied to a wide variety of bioassays involving the detection and phenotypic characterization of single cells. The bioassays include the rapid and automated detection of microbial pathogens and their antibiotic sensitivity from patient samples as well as the characterization of immune responses using a patient's own cells, including the killing of tumor cells.

Claim (Index 12):
A method of analyzing a cell phenotype, the method comprising the steps of:\n (a) providing a microfluidic device capable of forming aqueous microdroplets in oil, the device comprising a translucent microdroplet array chamber, and providing an imaging microscope; (b) preparing a plurality of aqueous microdroplets in oil using the microfluidic device, each microdroplet comprising a sample containing or suspected of containing one or more cells and one or more reagents for analyzing a phenotype of said cells; (c) directing the plurality of aqueous microdroplets into the microdroplet array chamber; (d) obtaining an image of the microdroplet array chamber using the imaging microscope; and (e) measuring an optical signal from said reagent, whereby information regarding the phenotype of said cells is obtained.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 86.0
- Lexical Diversity: 1.41818
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15317393', '14420646', '14982458', '11667277', '13970724']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.61046364794785
- 35 USC 102 Novelty (BERT): 0.508576307744936
- Combined Prediction Score: 0.6002749139275586
- Mean Citation Score: 250.354318
- Max Citation Score: 286.97946
- Similarity Product: 200.2393458029473

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test