PATENT CLAIM ANALYSIS

Application Number: 15907519
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-08
Patent Classification: ["435", "366000"]

Abstract:
PEGylated polyhemoglobin nanocapsules are provided, wherein the nanocapsules each include a core including polyhemoglobin, a polymer shell encapsulating the core, a polydopamine layer on an exterior surface of the shell, and poly(ethylene glycol) adhered by the polydopamine to the shell. A method of forming PEGylated polyhemoglobin nanocapsules includes extracting hemoglobin from red blood cells. The method further includes polymerizing the hemoglobin to provide polyhemoglobin. The polyhemoglobin is then encapsulated in a plurality of polymer shells to form a plurality of polyhemoglobin nanocapsules. In addition, a polydopamine is deposited on an external surface of the polyhemoglobin nanocapsules. Poly(ethylene glycol) is then adhered to the polyhemoglobin nanocapsules with the polydopamine to provide a plurality of PEGylated polyhemoglobin nanocapsules.

Claim (Index 8):
The method of  claim 1 , wherein said poly(ethylene glycol) includes poly(ethylene glycol) exhibiting a number average molecular weight (Mn) of 2,000 Da present in the range of 75 to 25 percent of the total weight of poly(ethylene glycol) and poly(ethylene glycol) exhibiting a number average molecular weight (Mn) of 5,000 Da present in the range of 25 percent to 75 percent of the total weight of the poly(ethylene glycol), wherein said amounts of poly(ethylene glycol) are selected to achieve 100% of the total weight.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 88.0
- Lexical Diversity: 2.21667
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10488116', '15480817', '15802015', '14891574', '13133241']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6213538727006955
- 35 USC 102 Novelty (BERT): 0.5210692767492348
- Combined Prediction Score: 0.6113254131055494
- Mean Citation Score: 236.37759
- Max Citation Score: 314.67102
- Similarity Product: 200.75409373187185

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test