PATENT CLAIM ANALYSIS

Application Number: 16010972
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["548", "546000"]

Abstract:
A hydrophilic polymer derivative having a benzylidene acetal linker whose hydrolysis rate at the pH of a weakly acidic environment in the living body can be accurately controlled. A hydrophilic polymer derivative having a benzylidene acetal linker, which is represented by the following formula (1): wherein R 1  is a hydrogen atom or a hydrocarbon group; R 2 , R 3 , R 4 , R 5 , and R 6  are each independently a hydrogen atom or a substituent and at least one of R 3 , R 4 , and R 5  is an electron-withdrawing substituent or at least one of R 2  and R 6  represents a substituent; X 1  is a chemically reactive functional group; P is a hydrophilic polymer; w is an integer of 1 to 8; and Z 1  and Z 2  are an independently selected divalent spacer.

Claim (Index 1):
A hydrophilic polymer derivative having a benzylidene acetal linker, which is represented by the following formula (1): wherein R 1  is a hydrogen atom or a hydrocarbon group;\n R 2 , R 3 , R 4 , R 5 , and R 6  are each independently a hydrogen atom or a substituent and at least one of R 3 , R 4 , and R 5  is an electron-withdrawing substituent or at least one of R 2  and R 6  is a substituent, with the proviso that when R 2  and R 6  are a hydrogen atom, one of R 3  to R 5  is a substituent selected from the group consisting of a trifluoromethyl group, a cyano group, an acetyl group, a methoxycarbonyl group and a nitro group; \n X 1  is a chemically reactive functional group selected from the group consisting of an active ester group, an active carbonate group, an aldehyde group, an isocyanate group, an isothiocyanate group, an epoxy group, a maleimide group, a vinyl sulfone group, an acryl group, a sulfonyloxy group, a carboxy group, a thiol group, a dithiopyridyl group, an \u03b1-haloacetyl group, an alkynyl group, an allyl group, a vinyl group, an amino group, an oxyamino group, a hydrazide group, and an azide group; \n P is a branched polyethylene glycol having a hydrocarbon group or a chemically reactive functional group different from X 1  at an end; \n w is an integer of 1 to 8; and \n Z 1  and Z 2  are an independently selected divalent spacer.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 94.0
- Lexical Diversity: 2.09459
- Patent Class: 548.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15764441', '15512727', '10048230', '12399249', '11142683']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7462293956399682
- 35 USC 102 Novelty (BERT): 0.5476135246936029
- Combined Prediction Score: 0.7263678085453317
- Mean Citation Score: 274.99311
- Max Citation Score: 394.31882
- Similarity Product: 333.3494588222647

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test