PATENT CLAIM ANALYSIS

Application Number: 15757269
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["424", "450000"]

Abstract:
The present disclosure is directed to methods of producing monosized protocells from monosized mesoporous silica nanoparticles (mMSNPs) and their use for targeted drug delivery formulations and systems and for biomedical applications. The present disclosure is also directed in part to a multilamellar or unilamellar protocell vaccine to deliver full length viral protein and/or plasmid encoded viral protein to antigen presenting cells (APCs) in order to induce an immunogenic response to a virus.

Claim (Index 26):
The population of protocells of  claim 1 , which comprises a plurality of unilamellar protocells comprising:\n a nanoporous silica or metal oxide core and a lipid bi-layer coating said core and an optional aqueous layer separating said core from said lipid bi-layer, said lipid bi-layer comprising: at least one Toll-like receptor (TLR) agonist; a fusogenic peptide; optionally at least one cell targeting species which selectively binds to a target on antigen presenting cells (APCs); and an endosomolytic peptide.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 1.36842
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14113371', '13143164', '12909572', '15320903', '14354706']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7319648136090604
- 35 USC 102 Novelty (BERT): 0.5578691402126758
- Combined Prediction Score: 0.7145552462694219
- Mean Citation Score: 348.0356040000001
- Max Citation Score: 464.6732
- Similarity Product: 322.8738651447058

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test