PATENT CLAIM ANALYSIS

Application Number: 15764283
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "532000"]

Abstract:
The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).

Claim (Index 3):
The compound of formula (I) according to  claim 1 , wherein\n L represents a C 2 -C 5 -alkylene group,\n wherein said group is optionally substituted with \n (i) one substituent selected from C 3 -C 4 -cycloalkyl- and hydroxymethyl-, and/or \n (ii) one or two additional substituents, identically or differently, selected from C 1 -C 2 -alkyl-, \n X, Y represent CH or N with the proviso that one of X and Y represents CH and one of X and Y represents N; R 1  represents a group selected from C 1 -C 4 -alkyl- and C 3 -C 5 -cycloalkyl-,\n wherein said group is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of hydroxy, cyano, halogen, C 1 -C 2 -alkyl-, C 1 -C 2 -alkoxy-, \u2014NH 2 , \u2014C(\u2550O)OH; \n R 2  represents a group selected from a hydrogen atom, a fluorine atom, a chlorine atom, cyano, methyl-, methoxy-, trifluoromethyl-; R 3  represents a group selected from a hydrogen atom, a fluorine atom, a chlorine atom, cyano, methyl-, methoxy-, trifluoromethyl-, trifluoromethoxy-; R 4  represents a hydrogen atom or a fluorine atom; R 5  represents a group selected from a hydrogen atom, cyano, \u2014C(\u2550O)R 8 , \u2014C(\u2550O)OR 8 , \u2014S(\u2550O) 2 R 8 , \u2014C(\u2550O)NR 6 R 7 , C 1 -C 4 -alkyl-, C 3 -C 5 -cycloalkyl-,\n wherein said C 1 -C 4 -alkyl- or C 3 -C 5 -cycloalkyl-group is optionally substituted with one substituent selected from the group consisting of fluorine, hydroxy, cyano, C 1 -C 3 -alkoxy-, \u2014NH 2 , alkylamino-, dialkylamino-, cyclic amines; \n R 6 , R 7  represent, independently from each other, a group selected from a hydrogen atom, C 1 -C 4 -alkyl- and C 3 -C 5 -cycloalkyl-,\n wherein said C 1 -C 4 -alkyl- or C 3 -C 5 -cycloalkyl-group is optionally substituted with one or two substituents, identically or differently, selected from the group consisting of hydroxy, C 1 -C 2 -alkyl-, C 1 -C 2 -alkoxy-, \u2014NH 2 , alkylamino-, dialkylamino-, cyclic amines, or \n R 6  and R 7 , together with the nitrogen atom they are attached to, form a cyclic amine; R 8  represents a group selected from C 1 -C 6 -alkyl-, fluoro-C 1 -C 3 -alkyl-, C 3 -C 5 -cycloalkyl- and phenyl-,\n wherein said group is optionally substituted with one substituent selected from the group consisting of halogen, hydroxy, C 1 -C 2 -alkyl-, C 1 -C 2 -alkoxy-, \u2014NH 2 , \n or an enantiomer, diastereomer, salt, solvate or salt of solvate thereof.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 90.0
- Lexical Diversity: 1.65909
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15303212', '15764289', '14345353', '14443368', '14443180']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8492415919280917
- 35 USC 102 Novelty (BERT): 0.5931389510496442
- Combined Prediction Score: 0.823631327840247
- Mean Citation Score: 421.604676
- Max Citation Score: 531.68835
- Similarity Product: 453.7236288270057

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test