PATENT CLAIM ANALYSIS

Application Number: 15971025
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["424", "186100"]

Abstract:
The present disclosure provides fusion proteins that incorporate unique mechanisms for multimerizing antigens to enhance their immunogenicity. The fusion proteins comprise at least two antigens, or other vaccine related proteins, separated by a linker sequence and an oligomerization domain. When expressed, the fusion protein forms a muKimeric protein complex, This approach can be used to muHimeri?.e a single antigen/protein or to create multimers comprising two or more different antigens/proteins. Also provided are nucleic acids encoding the fusion proteins. Yet another aspect is directed to methods of inducing or suppressing an immune response in a subject by administering to the subject a vaccine composition comprising a fusion protein or nucleic acid encoding the fusion protein, optionally without using an adjuvant.

Claim (Index 9):
The fusion protein of  claim 1 , wherein the fusion protein forms a multimeric protein complex when expressed in a host cell.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 93.0
- Lexical Diversity: 1.54118
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14416780', '11089426', '15558942', '09621268', '13946313']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7536286488037768
- 35 USC 102 Novelty (BERT): 0.6940035216819391
- Combined Prediction Score: 0.747666136091593
- Mean Citation Score: 407.746226
- Max Citation Score: 735.53503
- Similarity Product: 704.2594327393186

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test