PATENT CLAIM ANALYSIS

Application Number: 16336026
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "005000"]

Abstract:
The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens that, separated from each other, are applied to a solid phase, wherein at least the following antigens are used:          aa) the “non-structural protein 1” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, bb) an “envelope protein” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, cc) an “envelope protein” of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, dd) the “non-structural protein 1” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and ee) an “envelope protein” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids,           b) the solid phase is washed to separate non-specific bindings, c) the immune complex formed on the solid phase is converted into a signal and d) the test method is evaluated by comparing the relative signal strengths.

Claim (Index 1):
A method for the immunological differential diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein\n a) a sample is brought into contact with a plurality of antigens that, separated from each other, are applied to a solid phase, wherein at least the following antigens are used:\n aa) the \u201cnon-structural protein 1\u201d of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, \n bb) an \u201cenvelope protein\u201d of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, \n cc) an \u201cenvelope protein\u201d of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, \n dd) the \u201cnon-structural protein 1\u201d of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and \n ee) an \u201cenvelope protein\u201d of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids, \n b) the solid phase is washed to separate non-specific bindings, c) the immune complex formed on the solid phase is converted into a signal and d) the test method is evaluated by comparing the relative signal strengths, characterized in that the first arbovirus is a dengue virus serotype 2, the second arbovirus is a Chikungunya virus, the third arbovirus is a Zika virus.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 2.62791
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15812174', '16136386', '16136503', '15674585', '15674591']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6741991680917135
- 35 USC 102 Novelty (BERT): 0.5401548379252338
- Combined Prediction Score: 0.6607947350750656
- Mean Citation Score: 348.10456600000015
- Max Citation Score: 401.3132
- Similarity Product: 290.1405652129173

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test