PATENT CLAIM ANALYSIS

Application Number: 15925463
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-01
Patent Classification: ["436", "518000"]

Abstract:
Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.

Claim (Index 1):
A system for detecting a nucleic acid molecule of interest in a sample comprising:\n an optical sensor; a nucleic acid capture probe attached to a surface of the optical sensor, wherein the capture probe is capable of hybridizing to the nucleic acid molecule of interest to form a duplex; and an antibody capable of specifically binding to the duplex of the capture probe and nucleic acid molecule of interest, wherein said optical sensor has an optical property that is altered when said antibody is bound to said duplex such that said optical sensor is configured to sense said antibody combined with said duplex.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 2.1746
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14209746', '14234134', '15436585', '13979099', '11809867']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6644771449415459
- 35 USC 102 Novelty (BERT): 0.5042522330274669
- Combined Prediction Score: 0.648454653750138
- Mean Citation Score: 266.197624
- Max Citation Score: 309.56076
- Similarity Product: 220.19644087097168

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test