PATENT CLAIM ANALYSIS

Application Number: 15873293
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "255050"]

Abstract:
Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.

Claim (Index 12):
The compound according to  claim 1  comprising:\n N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenylamino)-6-ethoxypyrimidin-5-yl)-2-(1,2-dithiolan-3-yl)acetamide; \n N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-6-((R)-2,3-dihydroxypropoxy)pyrimidin-5-yl)-2-((S)-1,2-dithiolan-3-yl)acetamide; \n N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-6-((R)-2,3-dihydroxypropoxy)pyrimidin-5-yl)-2-((R)-1,2-dithiolan-3-yl)acetamide; \n N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-2-(1,2-dithiolan-3-yl)acetamide; \n S,S\u2032-(2-((2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)propane-1,3-diyl)diethanethioate; \n N-(2-((2-dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-1,2-dithiolane-4-carboxamide; \n S,S\u2032-(2-((3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)carbamoyl)propane-1,3-diyl)diethanethioate; \n N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)-1,2-dithiolane-4-carboxamide; \n S,S\u2032-(2-((3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)carbamoyl)propane-1,3-diyl)diethanethioate; \n N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)-1,2-dithiolane-4-carboxamide; \n or a pharmaceutically acceptable form thereof.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 1.15385
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15873255', '14913508', '16067444', '11048657', '14382074']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7557357657217004
- 35 USC 102 Novelty (BERT): 0.5379836186486081
- Combined Prediction Score: 0.7339605510143912
- Mean Citation Score: 330.21107600000005
- Max Citation Score: 363.78082
- Similarity Product: 282.64224078481675

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test