PATENT CLAIM ANALYSIS

Application Number: 16164395
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-06
Patent Classification: ["424", "490000"]

Abstract:
The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions. Methods generally involve administering nanoparticle compositions (e.g., nanoparticle compositions comprising at least one known therapeutic agent and/or independently active biologically active agent; and/or empty nanoparticle compositions) to a subject in need thereof.

Claim (Index 74):
A sterile, injectable pharmaceutical composition formulated for parenteral administration, wherein the pharmaceutical composition comprises a nanoparticle composition and a botulinum toxin,\n wherein the nanoparticle composition comprises a population of particles, wherein the majority of particles have diameters between approximately 10 and approximately 300 nanometers, wherein the nanoparticle composition consists essentially of at least one aqueous medium, at least one oil, and at least one surfactant, wherein the oil is a medium chain or long chain triglyceride, wherein the surfactant is a polysorbate, wherein the ratio of oil to surfactant is between about 0.5:1 to about 1:1, wherein the composition is substantially free of nucleic acids, wherein the composition is substantially free of parabens, wherein the botulinum toxin is present in a unit dose amount corresponding to 1-360 U of onabotulinumtoxinA for treatment of one or more of cervical dystonia, glabellar lines, constipation, blepharospasm, strabismus, upper limb spasticity, migraine, or facial wrinkles, wherein the pharmaceutical composition remains stable following prolonged storage for at least 12 months, when the prolonged storage is carried out at 2\u00b0 C. to 8\u00b0 C.; and wherein the composition is disposed within a device comprising a needle.

Metadata:
- Claim Count in Document: 152.0
- Percentile: 97.0
- Lexical Diversity: 1.29545
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15643945', '15288311', '13647759', '11607436', '12671693']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7372872465578714
- 35 USC 102 Novelty (BERT): 0.5242387019549912
- Combined Prediction Score: 0.7159823920975833
- Mean Citation Score: 259.665636
- Max Citation Score: 291.76315
- Similarity Product: 242.0912566996217

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test