PATENT CLAIM ANALYSIS

Application Number: 15984796
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["435", "134000"]

Abstract:
Disclosed are an enzymatic batchwise or continuous process for the production of fatty acid alkyl esters for use in the biofuels, food and detergent industries and a system therefor. The process utilizes enzymes immobilized on a hydrophobic resin mixed with a fatty acid source and an alcohol or alcohol donor in the presence of an alkaline or mild alkaline aqueous buffer, or in the presence of water or aqueous solution. The production process for fatty acid alkyl esters is carried out by transesterification or esterification simultaneously or sequentially. The biocatalyst activity is maintained with no significant activity losses in multiple uses and also avoids the accumulation of glycerol and water by-products or other hydrophilic compounds on the biocatalyst.

Claim (Index 22):
A process for simultaneous and/or sequential enzymatic transesterification and esterification of a fatty acid source with a C 1-6  alkyl alcohol, to form fatty acid C 1-6  alkyl esters, the process comprising the steps of:\n (1) providing a fatty acid source in a reaction vessel, wherein said fatty acid source comprises mono-, di- or tri-glycerides and their mixtures at any ratio, in the absence or presence of free fatty acids or their derivatives; (2) adding to said fatty acid source provided in step (1) at least one of an aqueous alkaline buffer solution and water, in an amount of at least 2% wt. of the fatty acid source, to give a mixture of said fatty acid source and at least one of an aqueous alkaline buffer solution or water; (3) adding to said mixture of fatty acid source and said at least one of aqueous alkaline buffer solution and water obtained in step (2) an immobilized lipase preparation, wherein the immobilized lipase preparation comprises at least one lipase immobilized on a hydrophobic porous polymeric support selected from the group consisting of a hydrophobic aliphatic polymer-based support, a hydrophobic acrylic polymer-based support, a hydrophobic aromatic polymer-based support; (4) stepwise adding to the mixture obtained in step (3) a C 1-6  alkyl alcohol or alcohol donor whilst mixing to give a reaction medium comprising said fatty acid source, immobilized enzyme, at least one of aqueous alkaline buffer solution and water and C 1-6  alkyl alcohol, wherein the reaction medium has a pH from about 4 to about 10; (5) allowing the reaction between said fatty acid source and said alcohol or alcohol donor to proceed in said vessel under stirring and/or shaking until conversion of the fatty acid acyl groups or free fatty acids comprised in said fatty acid source to fatty acid C 1-6  alkyl esters has reached at least 70%, to give fatty acid C 1-6  alkyl esters, glycerol and, respectively, water; (6) filtering off the reaction medium; and (7) separating the filtered reaction medium obtained in step (6) by phase separation and collecting an upper phase comprising fatty acid C 1-6  alkyl esters product and any unreacted residual fatty acid source, wherein said immobilized lipase preparation retains at least 80% of its activity for at least 20 production cycles.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 93.0
- Lexical Diversity: 1.74648
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13597304', '12744761', '14143258', '11946121', '13765782']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6646430946800174
- 35 USC 102 Novelty (BERT): 0.7225417679714516
- Combined Prediction Score: 0.6704329620091608
- Mean Citation Score: 520.7789319999998
- Max Citation Score: 795.9415
- Similarity Product: 789.7213093588355

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test