PATENT CLAIM ANALYSIS

Application Number: 15942345
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["540", "360000"]

Abstract:
A compound is represented as Formula I, a tautomer thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof: Compounds of Formula I are inhibitors of N-acylethanolamine hydrolyzing acid amidase (NAAA).

Claim (Index 16):
A method for expression, purification, protein characterization for hN-acylethanolamine hydrolyzing acid amidase and assay development to screen for hN-acylethanolamine hydrolyzing acid amidase inhibitors, the method comprising:\n a) constructing mammalian vectors for expressing C-terminal hexa-histidine tagged hNAAA; b) using the constructs for generation of a stable transfected HEK293 cell lines; c) optimization of hNAAA expression, secretion and purification conditions; and d) developing of fluorogenic assay for compounds screening and inhibitor characterization.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 90.0
- Lexical Diversity: 1.31034
- Patent Class: 540.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15311817', '15253773', '14770331', '15763724', '14169770']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.718539001840354
- 35 USC 102 Novelty (BERT): 0.5906685987539171
- Combined Prediction Score: 0.7057519615317104
- Mean Citation Score: 384.380926
- Max Citation Score: 623.34186
- Similarity Product: 393.8541726763702

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test