PATENT CLAIM ANALYSIS

Application Number: 16148265
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["514", "063000"]

Abstract:
The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.

Claim (Index 1):
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is cyclopropyl, cyclobutyl, or 3- or 4-membered heterocyclyl, wherein R 1  is optionally substituted with one or more groups selected from the group consisting of halo, alkyl, hydroxyalkyl and haloalkyl, \n R 2  and R 3  are independently \u2014H, halo, alkyl, alkoxy, \u2014CF 3 , or \u2014OCF 3 , \n R 4  is aryl, heteroaryl, cycloalkyl, heterocyclyl, or heteroalkyl, wherein R 4  is optionally substituted with one or more groups selected from the group consisting of halo, hydroxyl, alkyl, alkenyl, alkynyl, haloalkyl, hydroxyalkyl, trimethylsilylethoxymethyl, \u2014NO 2 , \u2014NR a R b , \u2014NR a C(\u2550O)R b , \u2014NR a C(\u2550O)NR a R b , \u2014NR a C(\u2550O)OR b , \u2014OR a , \u2014CN, \u2014C(\u2550O)R a , \u2014C(\u2550O)OR a , \u2014C(\u2550O)NR a R b , \u2014OC(O)R a , \u2014OC(\u2550O)OR a , \u2014OC(\u2550O)NR a R b , \u2014SR a , azetidinyl, oxetanyl, tetrahydrofuranyl, furanyl, pyrrolidinyl, pyrrolyl, pyrazolyl, thiophenyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, furazanyl, oxadiazolyl, thiadiazolyl, phenyl, tetrahydropyranyl, pyranyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, piperidinyl, piperazinyl, morpholinyl and thiomorpholinyl, and R a  and R b  are independently \u2014H, halo, amino, alkyl, or haloalkyl.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 97.0
- Lexical Diversity: 1.18919
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14776280', '15335279', '15851434', '15025996', '13780557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8384001005410475
- 35 USC 102 Novelty (BERT): 0.5366300092186022
- Combined Prediction Score: 0.8082230914088031
- Mean Citation Score: 362.723298
- Max Citation Score: 383.57654
- Similarity Product: 307.0281817853749

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test