PATENT CLAIM ANALYSIS

Application Number: 15972331
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["435", "006000"]

Abstract:
The invention relates to a method for the detection of oligonucleotides using anion exchange high performance liquid chromatography. Fluorescently labelled peptide nucleic acid oligomers, complementary to the oligonucleotide are hybridized to the oligonucleotides. Anion exchange high performance liquid chromatography is then performed and the hybridized moieties detected and quantitated. The invention also relates to a method for the simultaneous detection of both strands of an oligonucleotide in parallel from one sample, and a kit for use in qualitative and quantitative detection of one or two strands of an oligonucleotide.

Claim (Index 5):
The method according to  claim 1 , wherein quantitatively detecting detects RNA oligonucleotides that are extracellular and intracellular delivered siRNA.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 93.0
- Lexical Diversity: 1.75926
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15554456', '11100897', '12476193', '14648369', '10568134']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6184619783801846
- 35 USC 102 Novelty (BERT): 0.4860795837217843
- Combined Prediction Score: 0.6052237389143446
- Mean Citation Score: 203.036136
- Max Citation Score: 228.8201
- Similarity Product: 181.50627169692515

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test