PATENT CLAIM ANALYSIS

Application Number: 16031418
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["424", "141100"]

Abstract:
The present invention is directed to an anti-prion monoclonal antibody and its use for the treatment of conditions associated with or mediated by proteins or peptides having a toxic oligomeric form. These conditions include, but are not limited to, Alzheimer's disease, frontotemporal dementias, traumatic brain injury, and chronic traumatic encephalopathy.

Claim (Index 7):
The antibody or binding fragment thereof of  claim 1  further comprising:\n a light chain variable region, wherein said light chain variable region comprises:\n a complementarity-determining region 1 (L-CDR1) having an amino acid sequence of SEQ ID NO: 5, or a modified amino acid sequence of SEQ ID NO: 5, said modified sequence containing for 2 amino acid residue modifications as compared to SEQ ID NO: 5; \n a complementarity-determining region 2 (L-CDR2) having an amino acid sequence of SEQ ID NO: 6, or a modified amino acid sequence of SEQ ID NO: 6, said modified sequence containing 1 or 2 amino acid residue modifications as compared to SEQ ID NO: 6; and \n a complementarity-determining region 3 (L-CDR3) having an amino acid sequence of SEQ ID NO: 7, or a modified amino acid sequence of SEQ ID NO: 7, said modified sequence containing 1 or 2 amino acid residue modifications as compared to SEQ ID NO: 7.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 95.0
- Lexical Diversity: 1.20833
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13773264', '12999045', '14616300', '15324141', '14407724']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7045208590802428
- 35 USC 102 Novelty (BERT): 0.5383542405424191
- Combined Prediction Score: 0.6879041972264605
- Mean Citation Score: 357.33605400000016
- Max Citation Score: 366.13882
- Similarity Product: 251.79291484026555

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test