PATENT CLAIM ANALYSIS

Application Number: 15772861
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["546", "118000"]

Abstract:
There are provided compounds of formula (I), wherein X, Ak, s, L, Q, R 1  and R 2  have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of the JAK family) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.

Claim (Index 18):
A process for the preparation of a compound of formula I, as defined in  claim 1 , which process comprises:\n (a) reaction of a compound of formula II, wherein X, Ak, s, L and Q are as defined in  claim 1  and LG represents a leaving group, with a compound of formula III, wherein R 1  and R 2  are as defined in  claim 1 ; (b) for compounds of formula I in which L represents C(O), reaction of a compound of formula IV, wherein X, Ak and s as defined in  claim 1 , with a compound of formula VIII, wherein Q, R 1  and R 2  are as defined in  claim 1 ; (c) reaction of a compound of formula IV, as defined above, with a compound of formula IX, wherein LG 1  represents a leaving group and L, Q, R 1  and R 2  are as defined in  claim 1 ;\n (d) for compounds of formula I in which L represents CH 2 , reductive alkylation of a compound of formula IV, as defined above, with a compound of formula X, \n wherein Q, R 1  and R 2  are as defined in  claim 1 , in the presence of a reducing agent; or\n (e) deprotection of a protected derivative of a compound of formula I wherein the protected derivative bears a protecting group on an O- or N-atom of the compound of formula I.

Metadata:
- Claim Count in Document: 25.0
- Percentile: 93.0
- Lexical Diversity: 1.64706
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13542153', '14041387', '15772887', '13509442', '12468188']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8503950519181944
- 35 USC 102 Novelty (BERT): 0.57355707210899
- Combined Prediction Score: 0.822711253937274
- Mean Citation Score: 448.274146
- Max Citation Score: 513.91565
- Similarity Product: 371.0809182331026

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test