PATENT CLAIM ANALYSIS

Application Number: 16040043
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-04
Patent Classification: ["514", "217000"]

Abstract:
The present invention relates to, among other things, methods for treating trigeminal cephalgias such as migraine and migraine like headaches and other cerbrovascular conditions associated with pain and or inflammation. When non-steroidal anti inflammatory drugs (NSAIDs), such as ketoprofen, are applied locally using specific topical formulations immediate relief of pain is obtained. Intense pain is typically reduced to mild pain or no pain within 30 minutes of application of the topical formulation. The NSAID may be given in combination with other pharmacological agents, such as vasoconstrictors, opioids, decongestants and/or non-opioid migraine drugs, such as triptans and ergots an agents than affect serotonin receptors as agonists, antagonists or partial agonists. Drugs are delivered locally, targeting the nerve endings of the trigeminal nerve, as well as the occipital nerve and the intranasal terminals of the parasympathetic fibers originating in the Sphenopalatine ganglion. The administration preferably targets the extra cranial nerve endings of the trigeminal nerve in the temporal area, the extracranial occipital nerve endings in the occipital area, and the intranasal terminals of the trigeminal nerve and parasympathetic fibers originating in the Sphenopalatine ganglion. The delivery is carried out topically by way of injection or by transdermal application.

Claim (Index 64):
The method of  claim 59 , wherein the composition further comprises at least one therapeutic agent selected from the group consisting of an alpha adrenoceptor agonist, an anesthetic, an anticonvulsant, an anticholinergic compound, an antihistamine, a beta receptor antagonist, an ion channel blocking compound, a N-methyl d-aspartate receptor agonist, a norepinephrine reuptake inhibitor, an opioid, a serotonin agonist, serotonin partial agonist, a selective serotonin reuptake inhibitor, and a triptan.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 95.0
- Lexical Diversity: 1.9292
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11296079', '13474490', '12642545', '14803757', '10255036']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8010583748147095
- 35 USC 102 Novelty (BERT): 0.5084971350196419
- Combined Prediction Score: 0.7718022508352028
- Mean Citation Score: 254.101266
- Max Citation Score: 262.6093
- Similarity Product: 171.15804483686688

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test