PATENT CLAIM ANALYSIS

Application Number: 16105283
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["422", "502000"]

Abstract:
Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

Claim (Index 80):
A method for partitioning a fluid sample, the method comprising:\n providing a microfluidic device having a substrate comprising a plurality of microwells in fluid communication with an inlet; introducing a first fluid into the inlet of the microfluidic device, the first fluid comprising a biological sample and a plurality of beads, each bead comprising a reactive component for binding a target molecule from the biological sample to the bead; introducing a second fluid immiscible with the first fluid into the microfluidic device and flowing the second fluid towards each of the plurality of microwells so as to form partitions of fluid in corresponding microwells, each partition of fluid comprising a subvolume of the first fluid, including at least the biological sample and a single bead, wherein each partition of fluid is separated from one another by the second fluid; and maintaining each partition of fluid in corresponding microwells for detection of contents in each partition of fluid.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 96.0
- Lexical Diversity: 1.64062
- Patent Class: 422.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15415156', '14737865', '14070953', '12595107', '14294737']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6999429698200277
- 35 USC 102 Novelty (BERT): 0.498587460651114
- Combined Prediction Score: 0.6798074189031363
- Mean Citation Score: 273.55406
- Max Citation Score: 289.57425
- Similarity Product: 235.09339536443352

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test