PATENT CLAIM ANALYSIS

Application Number: 16087947
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["546", "053000"]

Abstract:
The present invention provides a medicament useful for treatment and/or prevention of cancer, a vaccine adjuvant, and an inhibitor of immune checkpoint comprising a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein Bonds a-d, Ring A, R 1 , R 1′ , R 2 , R 2′ , R 3 -R 8 , and n are as defined in the present specification.

Claim (Index 1):
A compound of formula (I): or a pharmaceutically acceptable salt thereof wherein\n Bonds a-c:   denote a single bond or a double bond, and Bond d: ---- denotes absent or a single bond, provided that when Bond a is a double bond, Bond b is a single bond; when Bond b is a double bond, Bond a is a single bond and R 5  is absent; when Bond c is a double bond, R 6  is absent; and when Bond c is a double bond and Bond d is a single bond, R 6  and R 7  are absent; \n Ring A is C 3-6  cycloalkyl ring, C 3-6  cycloalkenyl ring, or 5- or 6-membered monocyclic heterocycle, wherein the cycloalkyl ring, cycloalkenyl ring, and monocyclic heterocycle may be optionally substituted with one or more the same or different groups selected from the group consisting of halogen, hydroxy, oxo, amino, nitro, mono- or di-C 1-6  alkyl-amino, C 1-4  acyl, C 1-6  alkyl, C 1-6  haloalkyl, C 1-6  hydroxyalkyl, C 1-6  alkoxy, and C 1-6  haloalkoxy, at any substitutable position; \n R 1 , R 1\u2032 , R 2 , R 2\u2032 , and R 3  are independently hydrogen, halogen, hydroxy, amino, nitro, mono- or di-C 1-6  alkyl-amino, C 1-6  alkyl, C 1-6  haloalkyl, C 1-6  hydroxyalkyl, C 1-6  alkoxy, or C 1-6  haloalkoxy; \n R 4  is hydrogen, halogen, hydroxy, amino, mono- or di-C 1-6  alkyl-amino, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 1-6  alkoxy, C 3-6  cycloalkyl, 3- to 6-membered heterocycloalkyl, C 6-10  aryl, or 6- to 10-membered heteroaryl, wherein the alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl may be independently substituted with one or more the same or different groups selected from the group consisting of halogen, hydroxy, amino, nitro, mono- or di-C 1-6  alkylamino, C 1-4  acyl, C 1-6  alkyl, C 1-6  haloalkyl, C 1-6  hydroxyalkyl, C 1-6  alkoxy, and C 1-6  haloalkoxy, at any substitutable position; \n R 5 , R 6 , and R 7  are independently hydrogen, halogen, hydroxy, C 1-3  alkyl, C 1-3  haloalkyl, C 1-3  hydroxyalkyl, C 1-3  alkoxy, or C 1-3  haloalkoxy; \n R 8  is independently hydrogen, halogen, hydroxy, amino, nitro, mono- or di-C 1-6  alkyl-amino, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 1-6  alkoxy, benzyloxy, C 3-6  cycloalkyl, 3- to 6-membered heterocycloalkyl, C 6-10  aryl, or 6- to 10-membered heteroaryl, wherein the alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl may be independently substituted with one or more the same or different groups selected from the group consisting of halogen, hydroxy, amino, nitro, mono- or di-C 1-6  alkyl-amino, C 1-4  acyl, C 1-6  alkyl, C 1-6  haloalkyl, C 1-6  hydroxyalkyl, C 1-6  alkoxy, and C 1-6  haloalkoxy, at any substitutable position; and \n n is 1-4.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 97.0
- Lexical Diversity: 1.37037
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15766985', '14238507', '10932463', '11587906', '15799771']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7987732436669813
- 35 USC 102 Novelty (BERT): 0.5266768755199035
- Combined Prediction Score: 0.7715636068522735
- Mean Citation Score: 319.059382
- Max Citation Score: 326.9722
- Similarity Product: 207.3023832647562

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test