PATENT CLAIM ANALYSIS

Application Number: 15746964
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-11
Patent Classification: ["514", "168000"]

Abstract:
The invention relates to new compounds with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers, neurodegenerative diseases, inflammatory disorders, autoimmune disorders and metabolic disorders.

Claim (Index 3):
The compound of  claim 1 , wherein m is 0; R 1  is halogen; n is any integer of 1-2; R 3  is H; X is C(O); R 4  is H; and R 5  is OH; C 3-8 cycloalkyl; pyridinyl; phenyl substituted by one to three of NH 2 , halogen, OH, CN or C 1-4 alkylpiperazinyl; pyrinidinyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; pyrazinyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; thiazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; benzimidazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; pyrazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; indazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; thiazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; quinolinyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; indolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; indazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; azaindazolyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; deazapurinyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; indanyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; or morpholinoyl unsubstituted or substituted NO 2 , NH 2  or C 1-4 alkyl; or a tautomer, enantiomer, stereoisomer thereof, or a solvate, prodrug or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 86.0
- Lexical Diversity: 1.36111
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12555018', '12309459', '14790978', '13906626', '14592801']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8055569741549811
- 35 USC 102 Novelty (BERT): 0.5053523305479514
- Combined Prediction Score: 0.7755365097942781
- Mean Citation Score: 266.204172
- Max Citation Score: 272.8594
- Similarity Product: 207.74486424183848

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test