PATENT CLAIM ANALYSIS

Application Number: 15885608
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["435", "070300"]

Abstract:
The subject invention pertains to methods and apparatus for the production and purification of cell products, such as immunoglobulins. One aspect of the invention is an integrated cell culture and purification apparatus for the growth and maintenance of cells and the harvest and purification of cell products, such as immunoglobulins. Thus, the apparatus integrates a cell culture function with a purification function. Other aspects of the invention pertain to an automated method for producing immunogenic compositions such as vaccines.

Claim (Index 15):
The method of  claim 1 , wherein the first disposable cultureware module and the first reusable instrumentation base device are components of a cell culture unit, wherein the second disposable cultureware module and the second reusable instrumentation base device are components of a purification unit,\n wherein the pump comprises dual pumps for chromatography comprising a first pump and a second pump, and wherein the hardware of the first instrumentation base device further comprises a plurality of valves, wherein the cell growth chamber includes ports for movement of cell culture medium through the cell growth chamber, wherein the pumps and the plurality of valves circulate cell culture medium into and out of the cell growth chamber through the ports of the cell growth chamber, wherein the cell culture unit and the purification unit are connected by a fluid flow path there between, wherein the hardware of the second reusable instrumentation device receives fluid from the cell growth chamber through the fluid flow path, wherein the selection device comprises a chromatography device, wherein the second cultureware module further includes a diafiltration module that utilizes tangential flow filtration, an anion exchange filter, and a size-exclusion virus filter, wherein the chromatography device, diafiltration module, anion exchange filter, and size-exclusion virus filter are connected to the cell growth chamber of the cell culture unit by the fluid flow path, wherein the chromatography device separates a component from fluid received from the cell growth chamber, wherein the diafiltration module separates a component from fluid received from the chromatography device, wherein the anion exchange filter separates a component from fluid received from the diafiltration module or the chromatography device, and wherein the size-exclusion virus filter separates virus from fluid received from the chromatography device, the diafiltration module, or the anion exchange filter.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 86.0
- Lexical Diversity: 1.95455
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14516868', '12274993', '13664048', '14528007', '12274971']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6501171513292514
- 35 USC 102 Novelty (BERT): 0.5806427998561512
- Combined Prediction Score: 0.6431697161819414
- Mean Citation Score: 379.18085
- Max Citation Score: 522.84503
- Similarity Product: 414.67188336096166

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test