PATENT CLAIM ANALYSIS

Application Number: 15781997
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["546", "153000"]

Abstract:
Quinoline compounds and salts, hydrates or solvates serving as a selective uric acid reabsorption inhibitor, can be used in the treatment of hyperuricemia and gout by promoting uric acid to excrete from the body and reducing serum uric acid. Such compounds have the effect of reducing the uric acid in the animal body and human body.

Claim (Index 1):
A compound of formula (A) or optical isomers or solvates or pharmaceutically acceptable salts or pro-drugs thereof, Wherein, Z is selected from O, S or \u2014NH\u2014; W 1  is selected from N or CR a ; W 2  is selected from N or CR b ; W 3  is selected from N or CR c ; R a , R b , R c , R 2  and R 3  are independently selected from the group of hydrogen, halogen, cyano, nitro, alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclic radical, aryl, heteroaryl, \u2014OR d , \u2014S(O) m R d , \u2014C(O)R d , C(O)OR d , \u2014C(O)NR e R f , \u2014NR e R f  or NR e C(O)R f , respectively, wherein said alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclic radical, aryl, or heteroaryl are independently and optionally further substituted by one or more substituents that are selected from the group of halogen, cyano, nitro, oxo-, alkyl, haloalkyl, hydroxyalkyl, alkenyl, alkynyl, cycloalkyl, heterocyclic radical, aryl, heteroaryl, \u2014OR d , \u2014S(O) m R d , \u2014C(O)R d , C(O)OR d , \u2014C(O)NR e R f , \u2014NR e R f  or NR e C(O)R f , respectively; R d  is selected from the group of hydrogen, halogen, alkyl, cycloalkyl, heterocyclic radical, aryl or heteroaryl, wherein said alkyl, cycloalkyl, heterocyclic radical, aryl, or heteroaryl is independently and optionally further substituted by one or more substituents that are selected from the group of halogen, cyano, nitro, hydroxyl, oxo-, alkyl, haloalkyl, hydroxyalkyl, alkoxy, cycloalkyl, heterocyclic radical, aryl, heteroaryl, carboxyl, carboxylic ester, \u2014C(O)NR e R f , \u2014NR e R f  or NR e C(O)R f , respectively; R e , R f  are independently selected from the group of hydrogen, alkyl, cycloalkyl, heterocyclic radical, aryl or heteroaryl, respectively, wherein said alkyl, cycloalkyl, heterocyclic radical, aryl or heteroaryl are independently and optionally further substituted by one or more substituents selected from the group of halogen, cyano, nitro, hydroxyl, oxo-, alkyl, haloalkyl, hydroxyalkyl, alkoxy, cycloalkyl, heterocyclic radical, aryl, heteroaryl, carboxyl, carboxylic ester group, respectively; and m is 0, 1 or 2; X, Y are independently selected from the group of hydrogen, halogen, cyano, nitro, alkyl, cycloalkyl, haloalkyl or hydroxyalkyl, respectively; When Z is selected from O or S; R 4  is selected from hydrogen or C 1 -C 6  alkyl, cycloalkyl, wherein said alkyl and cycloalkyl are independently and optionally substituted by one or more substituents selected from halogen, cyano, nitro, hydroxyl, oxo-, alkyl, haloalkyl, hydroxyalkyl, alkoxy, cycloalkyl, heterocyclic radical, aryl, heteroaryl, carboxyl, carboxylic ester group, \u2014C(O)NR e R f , \u2014NR e R f  or NR e C(O)R f ; when Z is selected from \u2014NH\u2014, R 4  is selected from hydrogen, aryl or heteroaryl, and pyridyl is preferable.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 94.0
- Lexical Diversity: 1.53846
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15357613', '14679866', '14099276', '13093729', '12043456']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7914182810867577
- 35 USC 102 Novelty (BERT): 0.5280211149287638
- Combined Prediction Score: 0.7650785644709583
- Mean Citation Score: 335.818128
- Max Citation Score: 339.1581700000001
- Similarity Product: 263.46204103049405

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test