PATENT CLAIM ANALYSIS

Application Number: 16103649
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "002300"]

Abstract:
The present disclosure provides hNGAL muteins that bind a pyoverdine family member or pyochelin and can be used in various application including pharmaceutical applications, for example, to inhibit or reduce growth of  P. aeruginosa . The present disclosure also concerns methods of making one or more pyoverdine- or pyochelin-binding muteins described herein as well as compositions comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions comprising one or more of such muteins.

Claim (Index 20):
A nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide comprising a human neutrophil gelatinase-associated lipocalin (hNGAL) mutein polypeptide having binding specificity for pyoverdine type III, wherein the hNGAL mutein comprises 15 or more mutations at positions 36, 40, 41, 42, 49, 52, 65, 68, 70, 73, 77, 79, 81, 87, 96, 100, 103, 105, 106, 127, and 134 of SEQ ID NO: 1.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 96.0
- Lexical Diversity: 1.75758
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15814737', '15726577', '15726163', '15727087', '15203613']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8622666846982355
- 35 USC 102 Novelty (BERT): 0.7264201238346978
- Combined Prediction Score: 0.8486820286118818
- Mean Citation Score: 777.057688
- Max Citation Score: 824.20074
- Similarity Product: 781.5576330182648

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test