PATENT CLAIM ANALYSIS

Application Number: 16230609
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["435", "006120"]

Abstract:
Provided herein is method for, among other things, estimating the number of sequence variations in a sample of DNA. In some embodiments, the method can be used to estimate the mutational load of a sample. In some embodiments, the method makes use of a set of primers that have 3′ ends that specifically hybridizes to a sequence that is repeated multiple times in the genome. Thermocycling a reaction mix containing the primers may produce a reaction product comprising at least 50 amplicons having a total length of at least 100 kb. This product can be sequenced to provide an estimate of the number of sequence variations in the sample, and thus the mutational load of the sample.

Claim (Index 7):
The method of  claim 1 , wherein amplicons of (b) are less than 500 bases in length.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 98.0
- Lexical Diversity: 1.89552
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14527281', '13890512', '12449813', '14270805', '14795774']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6132536234906986
- 35 USC 102 Novelty (BERT): 0.5048514501002836
- Combined Prediction Score: 0.6024134061516571
- Mean Citation Score: 218.733174
- Max Citation Score: 225.53128
- Similarity Product: 136.66133733569623

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test