PATENT CLAIM ANALYSIS

Application Number: 15997422
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "04400A"]

Abstract:
A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.

Claim (Index 23):
A medical device comprising a purified population of primary cells comprising an exogenous mir construct or combination of constructs selected from the group consisting of mir1; mir133; mir138; mir206; mir208; mir126; mir1, mir133; mir1, mir138; mir1, mir206; mir1, mir208; mir133, mir138; mir133, mir206; mir133, mir208; mir138, mir206; mir138, mir208; mir206, mir208; mir1, mir138, mir208; mir1, mir206, mir208; mir138, mir206, mir208; mir1, mir133, mir206; mir1, mir133, mir208; mir1, mir138, mir206; mir133, mir138, mir208; and mir133, mir138, mir206; mir1, mir133, mir208, mir499-5p; mir1, mir133, mir206, mir499-5p; and mir499-5p.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 94.0
- Lexical Diversity: 1.21053
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13808311', '14440567', '15036357', '15853095', '14368149']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7502113328025094
- 35 USC 102 Novelty (BERT): 0.6314915096042154
- Combined Prediction Score: 0.73833935048268
- Mean Citation Score: 348.7022100000001
- Max Citation Score: 730.46484
- Similarity Product: 517.1025385750294

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test