PATENT CLAIM ANALYSIS

Application Number: 15978872
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "070100"]

Abstract:
Various embodiments of the present invention are directed to polyrotaxanes comprising a poloxamer core and at least one cyclodextrin and methods for treating Niemann-Pick type C (NPC) and imaging (e.g., MRI) using the polyrotaxanes various embodiments of the present invention.

Claim (Index 2):
A polyrotaxane comprising the general formula: or a salt thereof, wherein: n is an integer from 1 to 30; C and C\u2032 are the same or different and represent endcapping groups of the formula wherein: is a (C 1 -C 6 )hydrocarbylene group,\n G 1  and G 2 , together, form a radical having the formula: \n wherein each L 2  is independently a bond acyl; each G 3  is a substituted or unsubstituted (C 6 -C 50 )hydrocarbyl group, interrupted by 0 to 5 groups chosen from \u2014O\u2014, \u2014NH\u2014 and \u2014S\u2014; and each s is independently an integer from 1 to 5; and t is an integer from 2 to 5; B is a polyalkylene oxide polymer; and A is a beta cyclodextrin.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 93.0
- Lexical Diversity: 1.31429
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14889722', '14913978', '15183383', '15757062', '10594970']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6607771423031508
- 35 USC 102 Novelty (BERT): 0.4767498702686535
- Combined Prediction Score: 0.6423744150997011
- Mean Citation Score: 127.895876
- Max Citation Score: 216.67319
- Similarity Product: 199.55781687853576

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test