PATENT CLAIM ANALYSIS

Application Number: 15987365
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "256000"]

Abstract:
This invention provides for an improved method for differentially diagnosing ACTH-dependent Cushing's syndrome. Current practice for differentially diagnosing ectopic ACTH syndrome and Cushing's Disease measures relative ACTH concentrations from the inferior petrosal venous sinus compared to fluid obtained from a periphery venous sample. This is performed before and after administration of exogenous corticotropin releasing factor, or after administration of metyrapone. This invention uses glucocorticoid receptor antagonists to induce release of endogenous CRH which stimulates ACTH to increase in patients with ectopic ACTH syndrome but not in those with Cushing's Disease.

Claim (Index 2):
The method of  claim 1  wherein the periphery venous sample is a jugular venous sample.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 93.0
- Lexical Diversity: 1.48485
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15236015', '15796443', '15627414', '15697878', '15915477']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7975935514302795
- 35 USC 102 Novelty (BERT): 0.7000314632199017
- Combined Prediction Score: 0.7878373426092418
- Mean Citation Score: 512.1089400000002
- Max Citation Score: 713.4526
- Similarity Product: 709.3271986116766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test