PATENT CLAIM ANALYSIS

Application Number: 15765824
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "04400A"]

Abstract:
Disclosed are methods of treating a head and/or neck squamous cell carcinoma in an individual. The method may include the step of administering to an individual a composition comprising an interleukin-1 receptor-associated kinase 1 (IRAK1) inhibitor, which may include inhibitors that inhibit IL-1 receptor-associated kinase 1 in addition to other IL-1 receptor-associated kinases, such as, for example, an IRAK1/4 inhibitor.

Claim (Index 13):
A method of diagnosing and treating a head and/or neck squamous cell carcinoma in an individual, said method comprising:\n a) obtaining a plasma sample from said individual; b) detecting a IRAK1 protein or gene expression level in said sample; c) diagnosing said individual with a head and/or neck squamous cell carcinoma when the IRAK1 protein or gene expression level is increased in said sample as compared to a protein or gene expression level of IRAK1 in a healthy control; and d) administering an effective amount of an IRAK1 inhibitor.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 91.0
- Lexical Diversity: 1.41667
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14284521', '15288402', '14842049', '14604310', '14367837']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7450140707968945
- 35 USC 102 Novelty (BERT): 0.4880207895073967
- Combined Prediction Score: 0.7193147426679447
- Mean Citation Score: 214.531664
- Max Citation Score: 223.97466
- Similarity Product: 171.27467639150973

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test