PATENT CLAIM ANALYSIS

Application Number: 16096778
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-06
Patent Classification: ["546", "223000"]

Abstract:
A cyclohexene derivative or pharmaceutically acceptable salt thereof and application thereof, which belongs to the technical field of pharmaceutical technology is provided. The cyclohexene derivative of formula I or pharmaceutically acceptable salt thereof is a new broad-spectrum anti-influenza compound, having a great inhibiting effect on influenza viruses, specifically, it has a high activity to virus strains which is drug-resistant to Oseltamivir, and may be used as a broad-spectrum anti-influenza NA inhibitor effective to Tamiflu drug-resistance, for treating the flu caused by influenza viruses, thereby it is a broad-spectrum anti-influenza drug.

Claim (Index 9):
The method for preparing the injectable formulation of anti-influenza virus according to  claim 8 , wherein, in the step of solution preparation, the pharmaceutically acceptable excipient is sodium chloride added in a ratio by weight from 0.19:1 to 0.57:1 of the excipient and the compound of the formula I;\n in the step of freeze-drying, the freeze-drying was carried out according to the following processes: the temperature of shelves was set to \u221230 to \u221250\u00b0 C., and maintained for 3 to 5 hours; vacuuming was then conducted, the temperature was gradually raised by 7 to 15\u00b0 C. within 0.5 to 1.5 hours, and maintained for 1.5 to 2.5 hours; the temperature was then gradually raised by 7 to 15\u00b0 C. within 0.5 to 1.5 hours, and maintained for 2 to 4 hours; the temperature was then gradually raised by 7 to 15\u00b0 C. within 1.5 to 1.5 hours, and maintained for 2 to 4 hours; the temperature was then gradually raised up to 0\u00b0 C. within 0.5 to 1.5 hours, and maintained for 1.5 to 2.5 hours; the temperature was then gradually raised up to 15 to 25\u00b0 C. within 0.5 to 1.5 hours, and maintained for 1.5 to 2.5 hours; and the temperature was then gradually raised up to 35 to 45\u00b0 C. within 0.5 to 1.5 hours, and maintained for 4 to 10 hours.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 99.0
- Lexical Diversity: 1.57143
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13697794', '14779279', '14118768', '16062253', '13836356']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6293205711485226
- 35 USC 102 Novelty (BERT): 0.5180129293571457
- Combined Prediction Score: 0.6181898069693849
- Mean Citation Score: 242.371644
- Max Citation Score: 254.91457000000003
- Similarity Product: 158.40216613702714

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test