PATENT CLAIM ANALYSIS

Application Number: 16038389
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "006100"]

Abstract:
Disclosed herein are embodiments of a signaling conjugate, embodiments of a method of using the signaling conjugates, and embodiments of a kit comprising the signaling conjugate. The disclosed signaling conjugate comprises a latent reactive moiety and a chromogenic moiety that may further comprise a linker suitable for coupling the latent reactive moiety to the chromogenic moiety. The signaling conjugate may be used to detect one or more targets in a biological sample and are capable of being covalently deposited directly on or proximally to the target. Particular disclosed embodiments of the method of using the signaling conjugate comprise multiplexing methods.

Claim (Index 50):
The method of  claim 49 , further comprising:\n (f) repeating steps (a) through (c) with the substitution of a second target for said first target; a second detection probe for said first detection probe; a second enzyme conjugate for said first enzyme conjugate; a second binding complex for said first binding complex; a second amplifying conjugate for said first amplifying conjugate; a second hapten for said first hapten; a second amplifying complex for said first amplifying complex; a second labeling conjugate for said first labeling conjugate; and an anti-second hapten antibody for said anti-first hapten antibody; (g) after step (f), contacting said second labeling conjugate with a second chromogen whereby said enzyme of said second labeling conjugate catalyzes deposition of said second chromogen; and (h) after step (g), removing free second chromogen by washing by washing the biological sample.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 95.0
- Lexical Diversity: 1.96296
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13849160', '14769892', '14691826', '15246430', '15603079']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6039826080624509
- 35 USC 102 Novelty (BERT): 0.6128691906788489
- Combined Prediction Score: 0.6048712663240906
- Mean Citation Score: 419.83629200000007
- Max Citation Score: 733.6904
- Similarity Product: 460.8544952775955

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test