PATENT CLAIM ANALYSIS

Application Number: 16115969
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "019400"]

Abstract:
The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for NY-ESO-1. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a mammal and a method of treating or preventing cancer in a mammal using the inventive TCRs or related materials.

Claim (Index 28):
A method of detecting the presence of cancer in a mammal, comprising:\n (a) contacting a sample comprising one or more cells from the mammal with an isolated host cell or a population thereof, thereby forming a complex, and (b) detecting the complex, wherein detection of the complex is indicative of the presence of cancer in the mammal, wherein the isolated host cell expresses a T-cell receptor (TCR) having antigenic specificity for NY-ESO-1 (SEQ ID NO: 1) and comprising a murine variable region, wherein the TCR comprises the amino acid sequences of SEQ ID NOs: 3-8.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 96.0
- Lexical Diversity: 1.51724
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15267285', '14401893', '14427671', '15848344', '12443111']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7428742349484576
- 35 USC 102 Novelty (BERT): 0.550825739567488
- Combined Prediction Score: 0.7236693854103606
- Mean Citation Score: 317.24821000000014
- Max Citation Score: 395.32495
- Similarity Product: 355.8156553298861

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test