PATENT CLAIM ANALYSIS

Application Number: 16138369
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "252030"]

Abstract:
The present invention aims to provide a compound having a TrkA inhibitory action, a pharmaceutically acceptable salt thereof, or a solvate thereof, a pharmaceutical composition containing the same as an active ingredient, and a preventive and/or therapeutic agent for medicinal use, in particular for a disease in which TrkA in involved (pain, cancers, inflammation/inflammatory diseases, allergic diseases, skin diseases, neurodegenerative diseases, infectious diseases, Sjogren's syndrome, endometriosis, renal diseases, osteoporosis, and the like). Specifically, the present invention provides a compound or an optical isomer thereof, a pharmaceutically acceptable salt thereof, a solvate thereof, or the like, the compound represented by formula (I):

Claim (Index 27):
The pharmaceutical composition according to  claim 26 , wherein the disease is at least one disease selected from the group consisting of osteoarthritis pain, arthralgia, neuropathic pain, postoperative pain, lower back pain, diabetic neuropathy, intraoperative pain, cancer pain, chemotherapy-induced pain, headache including cluster headache, tension headache, and migraine pain, trigeminal neuralgia, herpes zoster pain, post herpetic neuralgia, carpal tunnel syndrome, inflammatory pain, pain from rheumatoid arthritis, colitis, interstitial cystitis pain, visceral pain, pain from the kidney stones, pain from gallstone, sore throat, fibromyalgia, chronic pain syndrome, thalamic pain syndrome, pain from a stroke, phantom limb pain, sunburn, radiculopathy, complex regional pain syndrome, HIV sensory neuropathy, central nervous disorder pain syndrome, multiple sclerosis pain, Parkinson's disease pain, spinal cord injury pain, menstrual pain, toothache, pain from bone metastasis, pain from endometriosis, pain from uterine fibroids, nociceptive pain, hyperalgesia, temporomandibular joint pain, neuroblastoma, ovarian cancer, endometrial cancer, pleomorphic glioblastoma, cervical cancer, pancreatic cancer, colon cancer, rectal cancer, prostate cancer, melanoma, myeloma, thyroid cancer, lung cancer including small cell lung cancer and non-small cell lung cancer, brain tumor, esophageal cancer, kidney cancer, osteoma and blood cancers including chronic myelogenous leukemia, acute lymphoblastic leukemia, Philadelphia chromosome positive acute lymphoblastic leukemia (PH+ALL), acute myelogenous leukemia (AML), and chronic lymphocytic leukemia (CML), squamous cell carcinoma, glioma, gastrointestinal cancer, ovarian cancer, liver cancer, gastric cancer, bladder cancer, hepatoma, breast cancer, head and neck cancer, germ cell tumor, pediatric sarcoma, paranasal sinus natural killer, multiple myeloma, interstitial cystitis (IC), painful bladder syndrome (PBS), urinary incontinence, inflammatory cystitis, ulcerative colitis, Crohn's disease, systemic lupus erythematosus rheumatoid arthritis, joint swelling, asthma, atopic dermatitis, psoriasis, psoriatic arthritis, rhinitis, systemic cutaneous pruritus, localized cutaneous pruritus, diffuse cutaneous pruritus, multiple sclerosis, Parkinson's disease, Alzheimer's disease, cruzi trypanosoma infection, Sjogren's syndrome, endometriosis, diabetic nephropathy, kidney fibrosis, chronic kidney disease, and osteoporosis.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 97.0
- Lexical Diversity: 1.89706
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11988659', '13392350', '13008456', '14442609', '14601775']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7924227661242704
- 35 USC 102 Novelty (BERT): 0.5253262262607128
- Combined Prediction Score: 0.7657131121379147
- Mean Citation Score: 301.63904999999994
- Max Citation Score: 317.48358
- Similarity Product: 224.1701180703092

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test