PATENT CLAIM ANALYSIS

Application Number: 15979054
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "450000"]

Abstract:
The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a mRNA solution and a lipid solution, wherein the mRNA solution and/or the lipid solution are at a pre-determined temperature greater than ambient temperature.

Claim (Index 52):
The process of  claim 48 , wherein the mRNA solution and the lipid solution are mixed into a dilute ethanol, resulting in a suspension of lipid nanoparticles.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 1.57143
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14790562', '15878131', '15809605', '15878137', '15451312']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7832324959113997
- 35 USC 102 Novelty (BERT): 0.5520767023624109
- Combined Prediction Score: 0.7601169165565008
- Mean Citation Score: 321.677014
- Max Citation Score: 360.9262
- Similarity Product: 276.26493645954133

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test