PATENT CLAIM ANALYSIS

Application Number: 15990487
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "006000"]

Abstract:
There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.

Claim (Index 15):
A compound of formula: where \u2018Spacer\u2019 of the compound is attached to a microarray with a plurality of electronically addressable electrodes, where the microarray includes a surface with a plurality of hydroxyl reactive group associated with the plurality of electronically addressable electrodes, where the Spacer is attached through one or more of the plurality of hydroxyl reactive groups, where \u2018Succinate Monomer\u2019 of the compound denotes a base, where \u2018Remainder of Oligonucleotide Strand\u2019 of the compound denotes a plurality of oligonucleotides each with a \u2018Succinate Monomer\u2019 at the 1\u2032 position, where the terminal oligonucleotide of the plurality of oligonucleotides has an acid labile protecting group on the 5\u2032 position, where the acid labile protecting group is susceptible to removal by supplying a voltage to one or more of the plurality of electronically addressable electrodes to generate acidic conditions to generate a 5\u2032 hydroxyl oligonucleotide species, where the succinate nucleoside moiety is susceptible to cleavage by introducing a base to cleave at a succinate site to generate a 3\u2032 hydroxyl nucleoside species.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 93.0
- Lexical Diversity: 1.67347
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12387115', '11361160', '15155046', '14082971', '13270865']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6541067790312246
- 35 USC 102 Novelty (BERT): 0.63447524449204
- Combined Prediction Score: 0.6521436255773061
- Mean Citation Score: 382.480378
- Max Citation Score: 604.58746
- Similarity Product: 466.0991824214196

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test