PATENT CLAIM ANALYSIS

Application Number: 15872571
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "312000"]

Abstract:
The present invention relates to certain compounds (e.g., imidazopyrazine, imidazopyridine, imidazopyridazine and imidazpyrimidine compounds) that act as inhibitors of the MAP kinase interacting kinases MNK2a, MNK2b, MNK1a, and MNK1b. The present invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of diseases (e.g., proliferative diseases (e.g., cancer), inflammatory diseases, Alzheimer's disease), as well as methods of treating these diseases.

Claim (Index 40):
The compound of  claim 35 , or a pharmaceutically acceptable salt thereof, wherein R 1  is \u2014C(O)R, wherein:\n R is of the formula: each R c  is independently optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl; each R d  is independently optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, \u2014COR e , S(O)R c , S(O) 2 R c , optionally substituted alkylaryl, or optionally substituted aryl; each R e  is independently hydrogen, halo, \u2014OH, \u2014OR c , \u2014NH 2 , \u2014NHR c , \u2014NHSO 2 R, \u2014NR f SO 2 R c , \u2014NR c R f , \u2014CN, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, \u2014COR c , or \u2014NHCOR c ; each R f  is independently \u2014H or C 1-6  alkyl; each R g  is independently hydrogen, halo, \u2014OH, \u2014OR c , \u2014NH 2 , \u2014NHR c , \u2014NHSO 2 R, \u2014NR f SO 2 R, \u2014NR c R f , \u2014CN, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, \u2014COR c , or \u2014NHCOR c ; and n is 1, or 2.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 1.84906
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14363718', '14517415', '15858733', '15308712', '14748990']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8379779014377906
- 35 USC 102 Novelty (BERT): 0.6013555735079978
- Combined Prediction Score: 0.8143156686448113
- Mean Citation Score: 473.944276
- Max Citation Score: 592.0943
- Similarity Product: 440.1413615488767

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test