PATENT CLAIM ANALYSIS

Application Number: 15998437
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "04400A"]

Abstract:
Compositions and methods for treatment of glioma are disclosed. In particular, the invention relates to methods of treating glioma by inhibiting pleiotrophin signaling to limit high-grade glioma invasion.

Claim (Index 20):
A method of inhibiting glioma tropism towards a brain subventricular zone in response to a chemoattractant complex, the method comprising administering to a subject in need thereof at least one inhibitory nucleic acid that inhibits expression of one or more genes selected from the group consisting of PTN, HSP90B, SPARC, and SPARCL1, wherein said at least one inhibitory nucleic acid is administered in an amount sufficient to interfere with assembly of the chemoattractant complex in the brain subventricular zone.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 96.0
- Lexical Diversity: 1.24
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14386319', '15527982', '13698429', '11436244', '14200840']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7408872091358014
- 35 USC 102 Novelty (BERT): 0.5014421229938594
- Combined Prediction Score: 0.7169427005216072
- Mean Citation Score: 212.271614
- Max Citation Score: 230.1344
- Similarity Product: 151.8721809551239

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test