PATENT CLAIM ANALYSIS

Application Number: 15904254
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["530", "350000"]

Abstract:
Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.

Claim (Index 9):
A composition for immunomodulation to achieve antigen-specific tolerance, the composition comprising:\n an antigen recombinantly fused or chemically conjugated with an erythrocyte-binding moiety; said antigen being recognizable by an immune system of a subject, the immune system of the subject being able to respond to the antigen with an unwanted immune response; wherein said erythrocyte-binding moiety comprises a polypeptide; wherein upon administration of the composition, said erythrocyte-binding moiety non-covalently and specifically binds an erythrocyte in situ in blood and presents said antigen to the immune system of the subject; wherein the erythrocyte-binding moiety does not specifically bind to other blood components, wherein the other blood components comprises blood proteins, albumin, fibronectin, platelets, and white blood cells; and wherein said composition elicits a tolerogenic response upon administration to said subject.

Metadata:
- Claim Count in Document: 51.0
- Percentile: 88.0
- Lexical Diversity: 1.38182
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15232713', '15904248', '15904228', '15232724', '15232714']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.812588434445277
- 35 USC 102 Novelty (BERT): 0.7132994234771908
- Combined Prediction Score: 0.8026595333484683
- Mean Citation Score: 727.8368780000003
- Max Citation Score: 790.30615
- Similarity Product: 761.1939393925667

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test