PATENT CLAIM ANALYSIS

Application Number: 15779435
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "235800"]

Abstract:
The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R 1  represents a hydrogen atom, an optionally substituted alkyl group, or the like; R 2  represents a hydrogen atom, a halogen atom, or the like; and R 3  represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

Claim (Index 2):
The compound according to  claim 1 , wherein\n the substituent of the optionally substituted aryl group and the optionally substituted heteroaryl group represented by Ring A is 1 to 3 groups each independently selected from the group consisting of a halogen atom and an alkoxy group; wherein said aryl moiety in the optionally substituted aryl group represented by Ring A is a 6 to 10 membered monocyclic or bicyclic aryl; said heteroaryl moiety in the optionally substituted heteroaryl group represented by Ring A is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; the substituent of the (1) optionally substituted alkyl group represented by R 1  is 1 to 3 groups independently selected from the group consisting of a halogen atom, a hydroxy group, a cyano group, an optionally substituted alkoxy group, an alkanoyl group, an optionally substituted aryl group, an optionally partially hydrogenated and optionally substituted heteroaryl group, an optionally substituted aliphatic heterocyclic group, an optionally substituted amino group, an optionally substituted carbamoyl group, and an optionally substituted sulfonyl group; the substituent of the (2) optionally substituted cycloalkyl group, (3) optionally substituted aryl group, (4) optionally substituted heteroaryl group, (5) optionally substituted aliphatic heterocyclic group, and (6) optionally substituted alkanoyl group is 1 to 3 groups each independently selected from the group consisting of a halogen atom, a hydroxy group, a cyano group, an optionally substituted alkyl group, an optionally substituted alkoxy group, an alkanoyl group, an optionally substituted aryl group, an optionally partially hydrogenated and optionally substituted heteroaryl group, an optionally substituted aliphatic heterocyclic group, an optionally substituted amino group, an optionally substituted carbamoyl group, and an optionally substituted sulfonyl group; wherein said aryl moiety in the optionally substituted aryl group represented by R 1  is a 6 to 10 membered monocyclic or bicyclic aryl; said heteroaryl moiety in the optionally substituted heteroaryl group represented by R 1  is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; said aliphatic heterocyclic moiety in the optionally substituted aliphatic heterocyclic group represented by R 1  is a 4 to 8 membered monocyclic aliphatic heterocyclic group comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; said aryl moiety in the optionally substituted aryl group in the substituent of the group represented by R 1  is a 6 to 10 membered monocyclic or bicyclic aryl; said heteroaryl moiety in the optionally partially hydrogenated and optionally substituted heteroaryl group in the substituent of the group represented by R 1  is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; said aliphatic heterocyclic moiety in the optionally substituted aliphatic heterocyclic group in the substituent of the group represented by R 1  is a 4 to 8 membered monocyclic aliphatic heterocyclic group comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; R 2  represents a hydrogen atom, a halogen atom, an alkyl group, a haloalkyl group, or an alkoxy group; R 3  represents a group of the following formula [II] [wherein:\n Ring B represents an aryl group, a cycloalkyl group, or a heteroaryl group; \n wherein said aryl moiety in the aryl group represented by Ring B is a 6 to 10 membered monocyclic or bicyclic aryl; \n said heteroaryl moiety in the heteroaryl group represented by Ring B is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; \n R 4 , R 5 , and R 6  represent each a group independently selected from the group consisting of a hydrogen atom; a halogen atom; an optionally substituted alkyl group; an optionally substituted cycloalkyl group; an optionally substituted heteroaryl group; an optionally substituted aliphatic heterocyclic group; and an amino group optionally substituted with 1 to 2 groups independently selected from the group consisting of an optionally substituted alkyl group; \n wherein the substituent of the (1) optionally substituted alkyl group represented by R 4 , R 5 , or R 6  is 1 to 2 groups independently selected from the group consisting of a hydroxy group; a halogen atom; an oxo group; a cyano group; an optionally substituted heteroaryl group; a carboxyl group; an alkoxycarbonyl group; an optionally substituted carbamoyl group; an alkylsulfonyl group; an alkylsulfonylamino group; an alkylsulfonylaminocarbonyl group; and an optionally substituted aminosulfonylaminocarbonyl group; \n the substituent of the (2) optionally substituted cycloalkyl group, (3) optionally substituted heteroaryl group, and (4) optionally substituted aliphatic heterocyclic group represented by R 4 , R 5 , or R 6  is 1 to 2 groups each independently selected from the group consisting of a hydroxy group; a halogen atom; an oxo group; a cyano group; an alkyl group; an optionally substituted heteroaryl group; a carboxyl group; an alkoxycarbonyl group; an optionally substituted carbamoyl group; an alkylsulfonyl group; an alkylsulfonylamino group; an alkylsulfonylaminocarbonyl group; and an optionally substituted aminosulfonylaminocarbonyl group; \n wherein said heteroaryl moiety in the optionally substituted heteroaryl group represented by R 4 , R 5 , or R 6  is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; \n said aliphatic heterocyclic moiety in the optionally substituted aliphatic heterocyclic group represented by R 4 , R 5 , or R 6  is a 4 to 8 membered monocyclic aliphatic heterocyclic group comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; and \n said heteroaryl moiety in the optionally substituted heteroaryl group in the substituent of the group represented by R 4 , R 5 , or R 6  is a 5 to 10 membered monocyclic or bicyclic heteroaryl comprising 1 to 4 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom] \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 42.0
- Percentile: 93.0
- Lexical Diversity: 2.03846
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15313407', '15305587', '13154144', '12919973', '14891845']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7233030306772935
- 35 USC 102 Novelty (BERT): 0.5579290960545166
- Combined Prediction Score: 0.7067656372150158
- Mean Citation Score: 313.940092
- Max Citation Score: 427.80472
- Similarity Product: 316.28444960038183

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test