PATENT CLAIM ANALYSIS

Application Number: 15918120
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "04400A"]

Abstract:
This document relates to materials and methods in assessing and treating mammals (e.g., humans) with precursor plasma cell (PC) disorders. Materials and methods for determining if a mammal (e.g., a mammal having a precursor plasma cell disorder) has an elevated level of 2-hydroxyglutarate (2-HG) that can be used to identify the precursor plasma cell disorder as likely to progress to a PC cancer (e.g., multiple myeloma) are provided. Materials and methods for treating a mammal having a precursor PC disorder at high risk of progressing to a PC cancer also are provided.

Claim (Index 17):
A method for assessing a precursor plasma cell (PC) disorder, wherein said method comprises:\n detecting the level of 2-hydroxyglutarate (2-HG) in a biological sample from a mammal; and identifying said mammal as having a precursor PC disorder at high risk of progressing to a PC cancer based at least in part on an elevated level of 2-HG.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 90.0
- Lexical Diversity: 1.89474
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11043209', '09821719', '14769888', '14433681', '14438715']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7252139776708633
- 35 USC 102 Novelty (BERT): 0.5158507943129956
- Combined Prediction Score: 0.7042776593350765
- Mean Citation Score: 208.90334
- Max Citation Score: 236.07089
- Similarity Product: 147.84730947444797

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test