PATENT CLAIM ANALYSIS

Application Number: 16009581
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["800", "279000"]

Abstract:
Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.

Claim (Index 1):
An engineered Vip3 pesticidal polypeptide comprising an amino acid sequence having at least 95% identity to SEQ ID NO:1 and further comprising at least one amino acid mutation at a position that corresponds to a position selected from the group consisting of M362, F400, R465, L494, 1503, L514, S532, E546, T600, T614, N625, Y629, K650, N682, S683, L701, T724, T743, S744, M747, T756, S761, T764, L766, R773, G778 and V785, wherein the at least one amino acid mutation is alanine (A), and wherein the mutation reduces or eliminates the pesticidal activity of the engineered polypeptide against at least  Ostrinia nubilalis  (European corn borer, ECB) while maintaining or increasing the activity against at least  Spodoptera frugiperda  (fall armyworm, FAW) compared to the ECB activity and the FAW activity of a wild-type Vip3 polypeptide that does not comprise the at least one mutation.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 94.0
- Lexical Diversity: 1.63636
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15960817', '14851555', '14851442', '13413707', '14910882']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6742671853152269
- 35 USC 102 Novelty (BERT): 0.5359223461251156
- Combined Prediction Score: 0.6604327013962157
- Mean Citation Score: 414.777094
- Max Citation Score: 417.7981
- Similarity Product: 297.48863836119176

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test