PATENT CLAIM ANALYSIS

Application Number: 15757149
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["435", "029000"]

Abstract:
The invention provides hydrogels and methods for three-dimensional (3D) culture of adult epithelial stem cells and uses thereof.

Claim (Index 3):
A method for obtaining an epithelial cell organoid, comprising culturing stem cells in a biofunctional 3D hydrogel, wherein:\n a) the cells comprise isolated tissue or organoid fragments and wherein the cells are cultured in conditions suitable for organoid formation; or b) the cells comprise single or clusters of stem cells, and wherein the cells are first cultured in conditions suitable for cell expansion and subsequently cultured in conditions suitable for organoid formation, wherein the hydrogel comprises a crosslinked hydrophilic polymer and a bioactive molecule, and wherein the hydrogel has a shear modulus between 0.05-3.1 kPa.

Metadata:
- Claim Count in Document: 51.0
- Percentile: 90.0
- Lexical Diversity: 1.05
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13147163', '13194866', '14775560', '15494291', '15310905']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5397472327815674
- 35 USC 102 Novelty (BERT): 0.537297164277336
- Combined Prediction Score: 0.5395022259311443
- Mean Citation Score: 320.820918
- Max Citation Score: 369.95496
- Similarity Product: 278.2840487480164

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test