PATENT CLAIM ANALYSIS

Application Number: 15984028
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "178000"]

Abstract:
Methods of treating a testosterone deficiency or its symptoms with a pharmaceutical formulation of testosterone esters are provided. The methods are designed to provide optimum plasma testosterone levels over an extended period.

Claim (Index 24):
A method of treating a population of humans suffering from chronic testosterone deficiency comprising the steps of:\n a. administering daily to the subject a defined dose of an oral pharmaceutical composition comprising a testosterone ester solubilized in a carrier comprising at least one lipophilic surfactant and at least one hydrophilic surfactant; b. collecting said subject's blood sample in tubes containing NaF; c. measuring the NaF-containing plasma testosterone concentration in the subject; and d. increasing the dose of testosterone ester administered in step a. when the measured plasma testosterone concentration in the subject is less than about 350 ng/dL, decreasing each dose of testosterone ester administered in step a. when the measured plasma testosterone concentration in the subject is greater than about 800 ng/dL, and maintaining each dose of testosterone ester administered in step a. when the measured plasma testosterone concentration in the subject is between about 350 ng/dL and about 800 ng/dL, wherein, after treatment, less than 25% of the population has a plasma testosterone C avg  below 252 ng/dL, less than 25% of the population has a plasma testosterone C avg  above about 907 ng/dL, and 75% of the population has a plasma testosterone C avg  between 252 ng/dL and 907 ng/dL.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 93.0
- Lexical Diversity: 1.21429
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12758770', '13584958', '15107492', '15723985', '14691229']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8042989458280755
- 35 USC 102 Novelty (BERT): 0.5446251322235774
- Combined Prediction Score: 0.7783315644676256
- Mean Citation Score: 385.839508
- Max Citation Score: 404.2631
- Similarity Product: 290.63913793967964

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test