PATENT CLAIM ANALYSIS

Application Number: 16129268
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["540", "462000"]

Abstract:
Disclosed is a method of preparing an amino acid ester of maytansinol by reacting maytansinol with an N-carboxyanhydride of an amino acid (NCA) in the presence of a drying agent. Also disclosed is an improved method of preparing an amino acid ester of maytansinol in which a nucleophile is added to the reaction mixture after completion of the reaction between maytansinol and an N-carboxyanhydride of an amino acid.

Claim (Index 10):
The method of  claim 9 , wherein the Lewis acid is selected from the group consisting of zinc triflate, zinc chloride, magnesium bromide, magnesium triflate, copper triflate, copper (II) bromide copper (II) chloride, and magnesium chloride.

Metadata:
- Claim Count in Document: 107.0
- Percentile: 97.0
- Lexical Diversity: 1.94595
- Patent Class: 540.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14037657', '14660050', '15708346', '15269163', '11500378']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7494904983902072
- 35 USC 102 Novelty (BERT): 0.5741955555241602
- Combined Prediction Score: 0.7319610041036025
- Mean Citation Score: 404.595818
- Max Citation Score: 470.679
- Similarity Product: 363.4198553922772

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test