PATENT CLAIM ANALYSIS

Application Number: 16107502
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "001000"]

Abstract:
Provided herein are methods of identifying a subject having a poly-ADP ribose polymerase (PARP) inhibitor-sensitive tumor by detecting a genomic gain in chromosome 1q21 and/or chromosome 20q13.3 in a tumor sample from the subject. Also provided are methods of identifying a subject having a PARP inhibitor-sensitive tumor by detecting gene amplification of a CHDIL gene or an RTEL1 gene in a tumor sample from the subject. Further provided are methods of treating a tumor with a genomic gain in chromosome 1q21 and/or chromosome 20q13.3 in a subject by administering an effective dose of a PARP inhibitor.

Claim (Index 1):
A method of identifying a subject having a poly-ADP ribose polymerase (PARP) inhibitor-sensitive tumor, comprising,\n detecting a genomic gain in chromosome 1q21 and/or chromosome 20q13.3 in a tumor sample from the subject, wherein the genomic gain is indicative of a tumor that is sensitive to PARP inhibitors.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 96.0
- Lexical Diversity: 2.24444
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14793878', '15524242', '15746806', '15494426', '13783785']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7553108146845293
- 35 USC 102 Novelty (BERT): 0.500984264379399
- Combined Prediction Score: 0.7298781596540164
- Mean Citation Score: 240.39025
- Max Citation Score: 245.8771
- Similarity Product: 172.00430058197975

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test