PATENT CLAIM ANALYSIS

Application Number: 16037678
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "254070"]

Abstract:
The present invention is directed to new bifunctional compounds and methods for treating HIV infections. The bifunctional small molecules, generally referred to as ARM-HI's, function through orthogonal pathways, by inhibiting the gp120-CD4 interaction, and by recruiting anti-DNP antibodies to gp120-expressing cells, thereby preventing cell infection and spread of HIV. It has been shown that ARM-HI's bind to gp120 and gp-120 expressing cells competitively with CD4, thereby decreasing viral infectivity as shown by an MT-2 cell assay, the binding leading to formation of a ternary complex by recruiting anti-DNP antibodies to bind thereto, the antibodies present in the ternary complex promoting the complement-dependent destruction of the gp120-expressing cells. Compounds and methods are described herein.

Claim (Index 56):
A compound of  claim 55  according to the chemical structure: where n is an integer from 1 to 6, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 95.0
- Lexical Diversity: 1.64935
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13988251', '15379969', '13501592', '14883959', '15890040']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7483774685502199
- 35 USC 102 Novelty (BERT): 0.5274709475320822
- Combined Prediction Score: 0.7262868164484062
- Mean Citation Score: 274.790116
- Max Citation Score: 310.8083
- Similarity Product: 218.17326131941672

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test