PATENT CLAIM ANALYSIS

Application Number: 16113482
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "040000"]

Abstract:
Provided herein are compositions and methods to improve treatment of chronic infections, and reduce, delay, or inhibit formation of biofilms, using specific combinations of aminoglycoside antibiotics and high, localized concentrations of one or more PMF stimulating compounds. These novel methods are easily adapted to clinical settings as toxicity and efficacy of the antibiotics and metabolites used have already been studied in vivo, and as dosing for both the antibiotics and metabolites are known. These approaches and therapeutic methods are also useful with non-metabolic chemicals that induce proton-motive force in bacteria.

Claim (Index 81):
The method of  claim 75 , wherein the biofilm comprises one or more bacteria selected from the group of:  Escherichia coli, Staphylococcus aureus, Pseudomonas, Proteus, Serratia, Citrobacter, Enterobacter, Klebsiella, Pseudomonas, Acinetobacter , and  Enterobacter.

Metadata:
- Claim Count in Document: 28.0
- Percentile: 96.0
- Lexical Diversity: 1.47761
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14115528', '15263766', '12812212', '15088915', '15724998']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.804129639736313
- 35 USC 102 Novelty (BERT): 0.6430465546702508
- Combined Prediction Score: 0.7880213312297069
- Mean Citation Score: 429.326018
- Max Citation Score: 702.11676
- Similarity Product: 551.1273166398669

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test