PATENT CLAIM ANALYSIS

Application Number: 15885258
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["534", "558000"]

Abstract:
The disclosure provides compounds having formula (I): and the pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 2 ′, and X are as defined as set forth in the specification. Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON). The disclosure also provides compounds having formula (I) for use in treating cancer.

Claim (Index 11):
The compound of  claim 1  having formula (IIA): or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is selected from the group consisting of H and C 1-6  alkyl; \n R 11  is selected from the group consisting of H, methyl, isopropyl, sec-butyl, CH 2 CH(CH 3 ) 2 , benzyl, p-hydroxybenzyl CH 2 OH, CH(OH)CH 3 , CH 2 -3-indoyl, CH 2 COOH, CH 2 CH 2 COOH, \u2014CH 2 C(O)NH 2 , CH 2 CH 2 C(O)NH 2 , CH 2 SH, CH 2 CH 2 SCH 3 , (CH 2 ) 4 NH 2 , (CH 2 ) 3 NHC(\u2550NH)NH 2 , and CH 2 -3-imidazoyl. \n R 12  is selected from the group consisting of H, C 1-4  alkyl, and \u2014C(\u2550O)R 13 ; and \n R 13  is C 1-4  alkyl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 86.0
- Lexical Diversity: 1.68889
- Patent Class: 534.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15885147', '15502105', '15419642', '15318627', '11150500']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6862962525339962
- 35 USC 102 Novelty (BERT): 0.5496308119139675
- Combined Prediction Score: 0.6726297084719933
- Mean Citation Score: 331.99464
- Max Citation Score: 421.0206
- Similarity Product: 364.6928493910789

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test