PATENT CLAIM ANALYSIS

Application Number: 16060078
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["435", "283100"]

Abstract:
An apparatus ( 8 ) for isolating corneal endothelial cells ( 34 ) (CECs) includes a base portion ( 10 ) having an interior recessed opening ( 14 ) with a bottom surface ( 16 ). A convex projection ( 18 ) is centrally located on the bottom surface ( 16 ) and is configured to receive an inverted cornea ( 32 ). A top portion ( 12 ) is configured to mate with the base portion ( 10 ). The top portion ( 12 ) includes a fluid chamber ( 24 ) with a lower surface ( 20 ). The lower surface ( 20 ) has an opening ( 22 ) therein in which the convex projection ( 18 ) projects when the top portion ( 12 ) is mated with the base portion ( 10 ).

Claim (Index 25):
An apparatus for isolating corneal endothelial cells (CECs), comprising:\n a base portion having an interior recessed opening with a bottom surface; a convex projection centrally located on the bottom surface; an inverted cornea disposed on the convex projection with an endothelial layer of the cornea facing upward; a top portion configured to mate with the base portion, the top portion including a fluid chamber with a lower surface, the lower surface having a central opening therein in which the convex projection projects when the top portion is mated with the base portion; and a groove formed on a lower exterior circumferential surface of the top portion and an O-ring disposed in the groove, wherein the O-ring provides a friction fit between the top portion and the base portion; wherein the lower surface of the top portion extends from and angles up and away from the opening therein and joins a side wall of the top portion, and the inverted cornea forms a fluid seal between the fluid chamber of the top portion and the interior recessed opening of the base portion and further wherein only the endothelial layer of the inverted cornea is exposed to the fluid chamber.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 2.37705
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14102953', '12712832', '14344011', '14362775', '12545040']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5307091083555647
- 35 USC 102 Novelty (BERT): 0.5022710115482991
- Combined Prediction Score: 0.5278652986748381
- Mean Citation Score: 195.10045
- Max Citation Score: 212.95497000000003
- Similarity Product: 137.89427887878122

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test