PATENT CLAIM ANALYSIS

Application Number: 15874938
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["530", "387300"]

Abstract:
The present invention relates to biological materials against P2X7 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the biological materials of the present invention inhibit the biological activity of the P2X7 receptor, such as activation by ATP.

Claim (Index 29):
A polypeptide comprising at least one immunoglobulin single variable domain that binds human P2X7, wherein the at least one immunoglobulin single variable domain comprises an amino acid sequence of formula 1: FR1 CDR1 FR2 CDR2 FR3 CDR3 FR4 (1); wherein FR1 to FR4 refer to framework regions 1 to 4 and are framework regions (FRs) of an immunoglobulin single variable domain; wherein CDR1 to CDR3 refer to complementarity determining regions 1 to 3 and are complementarity determining regions (CDRs) of an immunoglobulin single variable domain; and\n wherein CDR1 is chosen from the group consisting of: SEQ ID NO: 34 and polypeptides that have 1 amino acid difference with SEQ ID NO: 34; wherein CDR2 is chosen from the group consisting of: SEQ ID NO: 62 and polypeptides that have 1 amino acid difference with SEQ ID NO: 62; and wherein CDR3 is chosen from the group consisting of: SEQ ID NO: 90 and polypeptides that have 1 amino acid difference with SEQ ID NO: 90.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 86.0
- Lexical Diversity: 1.82979
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14403754', '14382027', '13937718', '15562437', '14402301']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6280492781350999
- 35 USC 102 Novelty (BERT): 0.7404608094446278
- Combined Prediction Score: 0.6392904312660527
- Mean Citation Score: 459.27668400000016
- Max Citation Score: 830.6749
- Similarity Product: 813.7933099180043

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test