PATENT CLAIM ANALYSIS

Application Number: 15970337
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-08
Patent Classification: ["548", "356100"]

Abstract:
Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.

Claim (Index 1):
A compound of Formula (III), or a pharmaceutically acceptable salt, or solvate thereof: wherein, R 1  is \u2014Cl, \u2014Br, \u2014CN, or C 3 -C 6 cycloalkyl; R 2  is H, halogen, \u2014CN, \u2014NO 2 , \u2014OH, \u2014OR 9 , \u2014SR 9 , \u2014S(\u2550O)R 9 , \u2014S(\u2550O) 2 R 9 , \u2014S(\u2550O) 2 N(R 10 ) 2 , C 1 -C 4 alkyl, C 1 -C 4 fluoroalkyl, C 1 -C 4 deuteroalkyl, or C 3 -C 6 cycloalkyl; R 3  is H, halogen, \u2014CN, \u2014OH, C 1 -C 4 alkyl, C 1 -C 4 fluoroalkyl, C 1 -C 4 deuteroalkyl, C 1 -C 4 alkoxy, or C 1 -C 4 fluoroalkoxy; W is CH, CF or N; each R A  is H, halogen, \u2014CN, \u2014NO 2 , \u2014OH, \u2014OR 9 , \u2014SR 9 , \u2014S(\u2550O)R 9 , \u2014S(\u2550O) 2 R 9 , \u2014S(\u2550O) 2 N(R 10 ) 2 , C 1 -C 6 alkyl, or C 1 -C 6 fluoroalkyl; L 1  is absent, C 1 -C 6 alkylene, or C 3 -C 6 cycloalkylene; Q is \u2014CO 2 H, \u2014CO 2 (C 1 -C 6 alkyl), \u2014OH, \u2014CN, \u2014B(OH) 2 , \u2014C(\u2550O)NHSO 2 R 9 , \u2014C(\u2550O)N(R 10 ) 2 , \u2014SO 2 NHC(\u2550O)R 9 , \u2014CN, tetrazolyl, \u2014OP(\u2550O)(OH) 2 , \u2014P(\u2550O)(OH) 2  or carboxylic acid bioisostere; Ring B is a monocyclic heteroaryl;\n each R B  is independently H, halogen, \u2014CN, \u2014NO 2 , \u2014OH, \u2014OR 9 , \u2014SR 9 , \u2014S(\u2550O)R 9 , \u2014S(\u2550O) 2 R 9 , \u2014S(\u2550O) 2 N(R 10 ) 2 , C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 1 -C 6 deuteroalkyl, C 1 -C 6 heteroalkyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 2 -C 10 heterocycloalkyl, substituted or unsubstituted phenyl, C 1 -C 4 alkylene-(substituted or unsubstituted phenyl), substituted unsubstituted monocyclic heteroaryl, C 1 -C 4 alkylene-(substituted or unsubstituted monocyclic heteroaryl), a substituted or unsubstituted bicyclic heteroaryl, or C 1 -C 4 alkylene-(substituted or unsubstituted bicyclic heteroaryl); \n n is 0, 1, or 2; \n R 9  is C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 1 -C 6 deuteroalkyl, C 3 -C 6 cycloalkyl, a substituted or unsubstituted phenyl, a substituted or unsubstituted monocyclic heteroaryl, or a substituted or unsubstituted bicyclic heteroaryl; each R 10  is independently H, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 1 -C 6 deuteroalkyl, C 3 -C 6 cycloalkyl, a substituted or unsubstituted phenyl, or a substituted or unsubstituted monocyclic heteroaryl; or two R 10  groups attached to the same N atom are taken together with the N atom to which they are attached to form a substituted or unsubstituted heterocycle.

Metadata:
- Claim Count in Document: 42.0
- Percentile: 93.0
- Lexical Diversity: 1.51724
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15261659', '15060398', '14926877', '15023465', '15036370']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7987053300398331
- 35 USC 102 Novelty (BERT): 0.6451016745616649
- Combined Prediction Score: 0.7833449644920163
- Mean Citation Score: 534.4068120000002
- Max Citation Score: 612.4017
- Similarity Product: 580.3118552418351

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test