PATENT CLAIM ANALYSIS

Application Number: 15924669
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["530", "300000"]

Abstract:
The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject. Preferably, the molecule comprises or consists of the structure: B j -[(Pro) n -X r His-Pro-His-Ala-Arg-Ile-Lys] m -R p , or B j -[lys-ile-arg-ala-his-pro-his-x r -(pro) n ] m -R p , or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-x r -(pro) n ] is the retro-inverso peptide of [(Pro) n -X r -His-Pro-His-Ala-Arg-Ile-Lys].

Claim (Index 18):
The molecule of  claim 5 , wherein the molecule comprises a structure selected from the group consisting of HPHARIK (SEQ ID NO: 3), HPHAR (SEQ ID NO: 4), PHPHAR (SEQ ID NO: 5), HPH, PHPH (SEQ ID NO: 6), PPHPH (SEQ ID NO: 7), PPPHPH (SEQ ID NO: 8), PHP, PPHP (SEQ ID NO: 9), PPPHP (SEQ ID NO: 10), PPPH (SEQ ID NO: 11), PPH, and PPP, such as a molecule that comprises a structure selected from the group consisting of Ac-HPHARIK-NH2 (SEQ ID NO: 12), Ac-HPHAR-NH2 (SEQ ID NO: 13), Ac-PHPHAR-NH2 (SEQ ID NO: 14), Ac-HPH-NH2, Ac-PHPH-NH2 (SEQ ID NO: 15), Ac-PPHPH-NH2 (SEQ ID NO: 16), Ac-PPPHPH-NH2 (SEQ ID NO: 17), Ac-PHP-NH2, Ac-PPHP-NH2 (SEQ ID NO: 18), Ac-PPPHP-NH2P (SEQ ID NO: 19), Ac-PPPH-NH2 (SEQ ID NO: 20), Ac-PPH-NH2 and Ac-PPP-NH2, where Ac is an acetyl group.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 90.0
- Lexical Diversity: 2.62637
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14888214', '14398260', '12514042', '14398297', '12309820']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7268253330226225
- 35 USC 102 Novelty (BERT): 0.5752803046955677
- Combined Prediction Score: 0.7116708301899171
- Mean Citation Score: 330.9352560000001
- Max Citation Score: 593.09985
- Similarity Product: 360.7732531847208

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test