PATENT CLAIM ANALYSIS

Application Number: 15762828
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "620000"]

Abstract:
The present disclosure relates to a pharmaceutical composition for inducing an exercise mimetic effect, which contains an α 1 -adrenergic receptor agonist as an active ingredient, and a method for screening a drug for inducing an exercise mimetic effect using the α 1 -adrenergic receptor agonist. The α 1 -adrenergic receptor agonist of the present disclosure increases the expression of p-AMPK, PPARδ and PGC-1α, which play key roles in maintaining and regulating energy metabolic activity in vivo, thereby increasing glucose uptake into skeletal muscle cells, suppressing adipocyte differentiation and lipid accumulation, reducing abdominal fat and body weight as well as regulating mitochondrial metabolic disorders and suppressing inflammatory responses. Accordingly, the α 1 -adrenergic receptor agonist can be usefully used to prevent and treat diseases requiring AMPK activation (metabolic diseases, cardiovascular diseases, inflammatory disease, etc.).

Claim (Index 1):
A pharmaceutical composition for inducing an exercise mimetic effect, comprising an \u03b1 1 -adrenergic receptor agonist or a pharmaceutically acceptable salt thereof as an active ingredient.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 90.0
- Lexical Diversity: 1.73563
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12810123', '14992969', '12994590', '15284267', '14432028']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7159415270876754
- 35 USC 102 Novelty (BERT): 0.5208666306831005
- Combined Prediction Score: 0.6964340374472179
- Mean Citation Score: 268.38238600000005
- Max Citation Score: 295.8875700000001
- Similarity Product: 209.6996833863813

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test