PATENT CLAIM ANALYSIS

Application Number: 15742408
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-11
Patent Classification: ["435", "006110"]

Abstract:
The present invention relates to a method for determining sensitivity to a simultaneous inhibitor against poly ADP ribose polymerase (PARP) and Tankyrase. According to the present invention, a colorectal treatment effect can be maximized by sorting patients having sensitivity to the simultaneous inhibitor against PARP and Tankyrase.

Claim (Index 1):
A method for determining susceptibility to a simultaneous inhibitor against PARP (Poly ADP Ribose Polymerase) and Tankyrase, the method comprising the following steps of:\n (a) isolating colorectal cancer cells from patient with colorectal cancers; (b) isolating nucleic acid molecules of colorectal cancer cells of the step (a); and (c) identifying genotypes of a p53 gene and an LIG4 (DNA ligase 4) gene in the nucleic acid molecule of the step (b), wherein where the genotype of the p53 gene is a normal type and the genotype of the LIG4 gene is a mutant type, it is determined that the patient is susceptibility to a simultaneous inhibitor against PARP and Tankyrase.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 86.0
- Lexical Diversity: 1.44444
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['09813824', '09174493', '11679803', '10555507', '13952561']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5948435060887132
- 35 USC 102 Novelty (BERT): 0.5002277704566681
- Combined Prediction Score: 0.5853819325255087
- Mean Citation Score: 239.035248
- Max Citation Score: 244.26163
- Similarity Product: 162.0179329993343

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test