PATENT CLAIM ANALYSIS

Application Number: 15756788
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["604", "020000"]

Abstract:
The presently-disclosed subject matter relates to analyte-activated photolabile compounds. The compounds include the formula: wherein Z includes a maskable molecule; L is selected from a bond, C, C(O), O, alkyl, (O)alkyl, and alkoxy; R 1  is selected from H, halogen, alkyl, and acyl; each R 2  is independently selected from H, alkyl, aryl, and acyl, and is optionally substituted with one or more heteroatoms independently selected from COOH and COO(alkyl); and R 3  is selected from H, alkyl, aryl, halogen, CN, OH, O(alkyl), O(aryl), SH, S(alkyl), S(aryl), amine, CHO, COOH, COO(alkyl), COO(aryl), PO 3 H 2 , and SO 3 H, and is optionally substituted with one or more heteroatoms independently selected from N, O, and S, halogen, OH, O(alkyl), O(aryl), SH, S(alkyl), S(aryl), amine, NO 2 , CHO, COO, COOH, COO(alkyl), COO(aryl), C(O)NR 2 , PO 3 H 2 , and/or SO 3 H. Also provided are methods of detecting calcium and treating a subject with the analyte-activated photolabile compounds.

Claim (Index 18):
A method for treating a subject, comprising:\n administering to the subject a compound of the formula: wherein:\n Z includes an active agent; \n L is selected from a bond, C, C(O), O, alkyl, (O)alkyl, and alkoxy; \n R 1  is selected from H, halogen, alkyl, and acyl; \n each R 2  is independently selected from H, alkyl, aryl, and acyl, and is optionally substituted with one or more heteroatoms independently selected from COOH and COO(alkyl), or the R 2  groups, taken together with the carbon atom to which they are bound, form a 4-10 membered ring; and \n R 3  is selected from H, alkyl, aryl, halogen, CN, OH, O(alkyl), O(aryl), SH, S(alkyl), S(aryl), amine, CHO, COOH, COO(alkyl), COO(aryl), PO 3 H 2 , and SO 3 H, R 3  being optionally substituted with one or more heteroatoms independently selected from N, O, and S, halogen, OH, O(alkyl), O(aryl), SH, S(alkyl), S(aryl), amine, NO 2 , CHO, COO, COOH, COO(alkyl), COO(aryl), C(O)NR 2 , PO 3 H 2 , and/or SO 3 H; and \n exposing the subject to an activation light.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 3.55405
- Patent Class: 604.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15897571', '15301270', '15213453', '10297352', '15746646']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7926623043784142
- 35 USC 102 Novelty (BERT): 0.5816344323334833
- Combined Prediction Score: 0.7715595171739211
- Mean Citation Score: 409.461456
- Max Citation Score: 506.421
- Similarity Product: 429.1104319033025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test