PATENT CLAIM ANALYSIS

Application Number: 16126683
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["435", "006100"]

Abstract:
The present invention provides a method for detecting transplantation failure of a transplanted organ or cells which comprises detecting a donor-positive but recipient-negative DNA marker in the recipient's plasma using pyrophosphorolysis activated polymerization. Because of the high sensitivity, specificity and selectivity of pyrophosphorolysis activated polymerization, transplantation failure can be detected at early stages and treatment can be initiate earlier.

Claim (Index 2):
The method of  claim 1 , wherein the screening and tracking are done using bi-directional pyrophosphorolysis activated polymerization.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.33333
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14000485', '13508318', '16110646', '14188455', '16110682']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5999507505218395
- 35 USC 102 Novelty (BERT): 0.5898457254876417
- Combined Prediction Score: 0.5989402480184198
- Mean Citation Score: 355.681236
- Max Citation Score: 703.0942
- Similarity Product: 384.91776653478144

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test