PATENT CLAIM ANALYSIS

Application Number: 15770369
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["514", "255050"]

Abstract:
Described are methods of use of compounds that inhibit PIF-mediated substrate binding by PDK1, which are useful as inhibitors of cancer growth or proliferation that is RSK2-dependent or AKT-independent. Also described are compositions of such compounds for use in such methods of treating cancer.

Claim (Index 9):
A pharmaceutical composition for use in treating cancer in a subject, in which the growth or proliferation of the cancer is dependent on a PDK1-PIF-mediated substrate interaction, comprising a formulation including a compound of Formula I and a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 91.0
- Lexical Diversity: 1.42424
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14966821', '10949714', '10350806', '13124773', '10922575']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8131656583592674
- 35 USC 102 Novelty (BERT): 0.5433770300098897
- Combined Prediction Score: 0.7861867955243296
- Mean Citation Score: 397.804354
- Max Citation Score: 416.61884
- Similarity Product: 277.9452810946464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test