PATENT CLAIM ANALYSIS

Application Number: 15752543
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["435", "157000"]

Abstract:
2-ketoacid decarboxylase enzymes, compositions encoding for 2 ketoacid decarboxylase enzymes, and host cells comprising such enzymes or compositions are provided

Claim (Index 1):
An expression cassette comprising a heterologous promoter operably linked to a nucleic acid encoding an enzyme comprising 2-ketoacid decarboxylase activity, wherein the enzyme:\n comprises a 3-layer alpha-beta-alpha sandwich; comprises a thiamine pyrophosphate (TPP) binding pocket; has a TM align score of at least 0.5 as compared against PDB ID:2VBG; and comprises at least a 100-fold greater catalytic efficiency for C8 2-ketoacid substrates as compared to C3 or isoC5 2-ketoacid substrates, wherein the catalytic efficiency is measured by kcat/Km.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 88.0
- Lexical Diversity: 1.29412
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15533390', '13077170', '15030616', '12540334', '13074907']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6093322779422559
- 35 USC 102 Novelty (BERT): 0.5260050677517708
- Combined Prediction Score: 0.6009995569232074
- Mean Citation Score: 284.4537600000001
- Max Citation Score: 354.87784
- Similarity Product: 249.4162810510444

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test