PATENT CLAIM ANALYSIS

Application Number: 15899721
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["436", "053000"]

Abstract:
Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent ( 2,6  dichloroquinone- 4 -chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the detected reaction product. A method of designing a personalized drug administration regime using the thus obtained concentration is also disclosed.

Claim (Index 5):
The apparatus of  claim 1 , wherein the filter stage is comprised in a solid phase extraction cartridge.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 2.52055
- Patent Class: 436.0
- Transitional Phrase Type: none
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14768421', '13878820', '13878815', '14236876', '14648203']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5914517247751705
- 35 USC 102 Novelty (BERT): 0.5893869222678569
- Combined Prediction Score: 0.5912452445244392
- Mean Citation Score: 280.48415800000004
- Max Citation Score: 514.65076
- Similarity Product: 430.3717016122247

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test