PATENT CLAIM ANALYSIS

Application Number: 15765168
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "235800"]

Abstract:
This invention is in the area of improved therapeutic combinations for and methods of treating selected cancers using selected pyrimidine compounds having pan-TAM or Mer/Axl dual receptor tyrosine kinase inhibitory activity in combination with immune checkpoint inhibitors. In one aspect, an improved treatment for select cancers is disclosed using selected pyrimidine compounds described herein in combination with an immune checkpoint inhibitor, for example, a cytotoxic T-lymphocyte-associated protein 4 (CTLA4) inhibitor, a programmed cell death protein 1 (PD1) inhibitor, or a programmed death-ligand 1 (PDL-1) inhibitor, or combination thereof.

Claim (Index 47):
A method of inhibiting an Axl and Mer kinase in a subject in need thereof comprising administering an effective amount of the compound of  claim 31 .

Metadata:
- Claim Count in Document: 47.0
- Percentile: 90.0
- Lexical Diversity: 1.61905
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15419642', '14678905', '15619671', '15752896', '15576101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.737570333457612
- 35 USC 102 Novelty (BERT): 0.5317335094051934
- Combined Prediction Score: 0.7169866510523701
- Mean Citation Score: 303.095946
- Max Citation Score: 316.93295
- Similarity Product: 181.3400421189457

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test