PATENT CLAIM ANALYSIS

Application Number: 16182443
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-02
Patent Classification: ["424", "235100"]

Abstract:
The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.

Claim (Index 12):
A method of treating a cancer in a subject in need thereof, the method comprising:\n (a) obtaining or having obtained an immunotherapy-based viral delivery system comprising:\n (i) at least one helper plasmid comprising DNA sequences for expressing a functional protein derived from each of a gag, pol, and rev gene; \n (ii) an envelope plasmid comprising a DNA sequence for expressing an envelope protein capable of infecting a target cell; and \n (iii) a therapeutic vector comprising: \n at least one encoded shRNA capable of inhibiting production of an enzyme of the mevalonate pathway; \n or, \n at least one encoded microRNA capable of inhibiting production of an enzyme of the mevalonate pathway; \n (b) transfecting or having transfected the immunotherapy-based viral delivery system into a packaging cell to produce an immunotherapy-based composition; and (c) administering or having administered a therapeutically-effective amount of the immunotherapy-based composition to the subject.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 98.0
- Lexical Diversity: 1.15625
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15706481', '16008991', '15849062', '15652080', '15904131']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8318453489279684
- 35 USC 102 Novelty (BERT): 0.7177688915659785
- Combined Prediction Score: 0.8204377031917693
- Mean Citation Score: 733.273308
- Max Citation Score: 763.8657
- Similarity Product: 698.3546673209665

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test