PATENT CLAIM ANALYSIS

Application Number: 15750811
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "456000"]

Abstract:
Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided.

Claim (Index 135):
A method of treating a subject having a mast cell related disorder comprising:\n (a) determining whether a subject has an increased concentration of one or more biomarkers in the blood of the subject; and (b) administering to a subject having an increased concentration of the one or more biomarkers in the blood of the subject a composition comprising a mast cell stabilizer; wherein the one or more biomarkers is selected from tryptase, histamine, chymase, interleukin-6, interleukin-4, interleukin-5, interleukin-8, tumor growth factor alpha (TGF-\u03b1), tumor growth factor beta (TGF-\u03b2), tumor necrosis factor alpha (TNF-\u03b1), tumor necrosis factor beta (TNF-\u03b2), fibroblast growth factor 2 (FGF2), nerve growth factor (NGF), vascular endothelial growth factor (VEGF), stem cell factor (SCF), vascular cell adhesion molecule 1 (VCAM-1), ICAM-1 (Intercellular Adhesion Molecule 1), immunoglobulin E (IgE), matrix metalloproteinase-3 (MMP-3), matrix metallopeptidase-9 (MMP-9), vascular endothelial growth factor A (VEGF-A), vascular endothelial growth factor C (VEGF-C), vascular endothelial growth factor D (VEGF-D) macrophage inflammatory protein 1\u03b1 (MIP-1\u03b1), N-methyl histamine, methylimidazole acetic acid, and prostaglandin D2.

Metadata:
- Claim Count in Document: 83.0
- Percentile: 88.0
- Lexical Diversity: 1.22222
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15750809', '14686535', '15887830', '15117711', '15621857']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7998302072207562
- 35 USC 102 Novelty (BERT): 0.5556488062042921
- Combined Prediction Score: 0.7754120671191097
- Mean Citation Score: 350.914104
- Max Citation Score: 432.72552
- Similarity Product: 286.4917376141024

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test