PATENT CLAIM ANALYSIS

Application Number: 15971399
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "256000"]

Abstract:
The present invention is concerned with indolin-2-one derivatives of general formula wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from   or the oxygen atom may form together with two neighboring carbon atoms from the group A an additional fused ring, selected from R 1  is hydrogen, lower alkyl, lower alkyl substituted by halogen or oxetanyl; R 2  is hydrogen, lower alkyl lower alkoxy, halogen or cycloalkyl; --- the dotted line is nothing or may be —CH 2 —; as well as with a pharmaceutically acceptable salt thereof, with a racemic mixture, or with its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.  The compounds may be used in the treatment of CNS diseases related to positive (psychosis) and negative symptoms of schizophrenia, substance abuse, alcohol and drug addiction, obsessive-compulsive disorders, cognitive impairment, bipolar disorders, mood disorders, major depression, treatment resistant depression, anxiety disorders, Alzheimer's disease, autism, Parkinson's disease, chronic pain, borderline personality disorder, neurodegenerative disease, sleep disturbances, chronic fatigue syndrome, stiffness, inflammatory disease, asthma, Huntington's disease, ADHD, amyotrophic lateral sclerosis, effects in arthritis, autoimmune disease, viral and fungal infections, cardiovascular diseases, ophthalmology and inflammatory retinal diseases and balance problems, epilepsy and neurodevelopmental disorders with co morbid epilepsy.

Claim (Index 12):
A compound of formula IF according to  claim 1 wherein R 1  is hydrogen, lower alkyl, lower alkyl substituted by halogen or oxetanyl; R 2  is hydrogen, lower alkyl lower alkoxy, halogen or cycloalkyl; --- the dotted line is nothing or may be \u2014CH 2 \u2014; as well as a pharmaceutically acceptable salt thereof, a racemic mixture, or its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.74658
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15971426', '15971368', '14971120', '15353355', '14645033']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.796000394094411
- 35 USC 102 Novelty (BERT): 0.5826065056064814
- Combined Prediction Score: 0.7746610052456181
- Mean Citation Score: 407.647514
- Max Citation Score: 487.28015
- Similarity Product: 395.6792832937956

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test