PATENT CLAIM ANALYSIS

Application Number: 15911955
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-09
Patent Classification: ["424", "486000"]

Abstract:
The present invention is directed to tissue sealant compositions comprising: a multi-arm reactive polyethylene glycol polymer having at least 3 electrophilic groups; albumin; a buffer; water; and entrained gas as bubbles; wherein concentration of albumin in a liquid component of the sealant is within range of 50-200 mg/ml; and wherein concentration of multi-arm PEG in said liquid component of the sealant is within range of 25-100 mg/mL and wherein PEG-SG portion is composed of a blend of 2 PEG-SG different in arm number or arm lengths.

Claim (Index 1):
A tissue sealant comprising:\n a) A liquid component containing\n a. At least two different multi-arm poly(ethylene glycol) succinimidyl glutarate (PEG-SG) components, each having at least 3 electrophilic groups; \n b. albumin; \n c. a buffering agent; \n d. water; and \n b) entrained gas as bubbles; wherein a combination of (a-d) produces a compliant soft set foam with closed cell; wherein the liquid component has an albumin concentration in range of 50 to 200 mg/ml; wherein a first PEG-SG component is a four-arm poly(ethylene glycol) succinimidyl glutarate having an average molecular weight 20,000 Dalton (PEG-SG4-20K) having a liquid concentration of between 20 to 45 mg/ml and a second PEG-SG component is a two-arm poly(ethylene glycol) succinimidyl glutarate having an average molecular weight of 10,000 Dalton (PEG-SG2-10K) having a liquid concentration of between 5 to 30 mg/ml, and wherein the sum of the liquid concentrations for both PEG-SG components is 50 mg/ml, and wherein gas space comprises 55% to 75% of the foam by volume.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 90.0
- Lexical Diversity: 1.62069
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13107375', '14685175', '13748678', '13820440', '14696390']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6715328685303206
- 35 USC 102 Novelty (BERT): 0.4822661526832232
- Combined Prediction Score: 0.6526061969456108
- Mean Citation Score: 186.540352
- Max Citation Score: 192.22444
- Similarity Product: 140.23740971675872

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test