PATENT CLAIM ANALYSIS

Application Number: 16009647
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["435", "007920"]

Abstract:
The present invention relates to a method for diagnosing a disease comprising the step detecting in a sample comprising antibodies from a patient an autoantibody binding to a polypeptide selected from the group comprising NSF, STX1B, DNM1 and VAMP2, a polypeptide comprising a polypeptide selected from the group comprising NSF, STX1B, DNM1 and VAMP2, or a variant thereof, a use of said polypeptide for the diagnosis of a disease, an autoantibody binding to a polypeptide selected from the group comprising NSF, STX1B, DNM1 and VAMP2, a use of the autoantibody for the diagnosis of a disease, a method for isolating an autoantibody binding to a polypeptide selected from the group comprising NSF, STX1B, DNM1 and VAMP2, a pharmaceutical composition or medical device comprising said polypeptide according to the present invention, a kit for the diagnosis of a disease comprising said polypeptide or said medical device and a use of said polypeptide or autoantibody for the manufacture of a kit or medical device.

Claim (Index 7):
A method for treating a neurological disease, comprising:\n a) detecting an autoantibody that binds to a polypeptide selected from the group consisting of NSF, STX1B, DNM1 and VAMP2 in a sample of a patient by contacting the sample of the patient that comprises antibodies with the polypeptide or variants thereof, and b) if the autoantibody is detected in the sample of the patient,\n i) reducing the concentration of the autoantibody in the blood of the patient, or \n ii) administering one or more immunosuppressive pharmaceutical substances.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 94.0
- Lexical Diversity: 3.80851
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15954019', '15172450', '15046950', '14122318', '13988269']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5708954762265456
- 35 USC 102 Novelty (BERT): 0.5759084859344662
- Combined Prediction Score: 0.5713967771973377
- Mean Citation Score: 317.2510200000001
- Max Citation Score: 486.32635
- Similarity Product: 382.6040177061736

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test