PATENT CLAIM ANALYSIS

Application Number: 16225484
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["514", "210180"]

Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R 1 , R 2 , R 5 , and R 8  are as described herein.

Claim (Index 7):
The compound of  claim 1 , having the Formula III or a pharmaceutically acceptable salt, enantiomer, hydrate, solvate, prodrug, isomer, or tautomer thereof, wherein: Ar is pyrazolyl or phenyl; R 4  is hydrogen, \u2014O(CH 2 ) n R d , \u2014O(CH 2 ) n C(O)R d , or \u2014O(CH 2 ) n S(O) 2 R d ; R 8  is methyl, methoxy, or cyclopropyl; R a  and R b  are independently hydrogen or C 1 -C 6  alkyl; R c  is \u2014(CH 2 ) n R a , \u2014(CH 2 ) n OR a , \u2014C(O)R a , \u2014C(O)OR a , \u2014C(O)NR a R b , \u2014(CH 2 ) n S(O) 2 CH 3 , \u2014S(O) 2 R a , \u2014S(O) 2 NR a R b , C 1 -C 6  haloalkyl, C 1 -C 6  haloalkoxy, cycloalkyl, heterocycloalkyl, halo, cyano, or oxo; R d  is hydrogen, NH(C 1 -C 6  alkyl), N(C 1 -C 6  alkyl) 2 , C 1 -C 6  alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, wherein said alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are optionally substituted with one or more substituents independently selected from R a , R b , and R c ; and n is 0, 1, or 2.

Metadata:
- Claim Count in Document: 115.0
- Percentile: 98.0
- Lexical Diversity: 1.37778
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14546775', '15937271', '14546896', '16029166', '16016955']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8211053015877599
- 35 USC 102 Novelty (BERT): 0.6897849601323093
- Combined Prediction Score: 0.8079732674422148
- Mean Citation Score: 488.26624
- Max Citation Score: 655.55743
- Similarity Product: 648.3629976742518

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test