PATENT CLAIM ANALYSIS

Application Number: 15902537
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["546", "015000"]

Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1, or a salt thereof, wherein Q, R 1 , R 2 , R 3  and R 4  are as defined herein.

Claim (Index 27):
A compound of the formula (1b): or a salt thereof, wherein Q is an optionally substituted five-membered heterocyclic ring containing 1, 2, 3 or 4 heteroatom ring members selected from N, O and S substituted with one or more groups selected from (L)-R 10 , (L)-R 11  and (L)-R 12 , where L is a bond or a CH 2  group; R 10 , R 11  and R 12  are independently selected from hydrogen; fluorine; chlorine; cyano; oxo; hydroxy; OR 15 ; NR 15 R 16 ; COOR 15 ; CONR 15 R 16 ; a C 1-6  non-aromatic hydrocarbon group which is optionally substituted with one to six fluorine atoms and wherein one carbon atom of the hydrocarbon group may optionally be replaced by an O heteroatom; and an optionally substituted 5-membered ring containing 0, 1, 2, 3 or 4 heteroatoms selected from O, N and S wherein the optional substituents are selected from hydrogen and a C 1-6  non-aromatic hydrocarbon group; wherein R 15  and R 16  are the same or different and are independently selected from hydrogen; a non-aromatic C 1-6  hydrocarbon group optionally substituted with one or more fluorine atoms and wherein one carbon atom of the hydrocarbon group may optionally be replaced by a heteroatom selected from O and N; R 3  is selected from hydrogen; fluorine; cyano; hydroxy; methoxy; or methyl; R 4  is a hydrogen or a C 1-6  non-aromatic hydrocarbon group which is optionally substituted with one to six fluorine atoms; and the dotted line indicates an optional second carbon-carbon bond, provided that when a second carbon-carbon bond is present, then R 3  is absent.

Metadata:
- Claim Count in Document: 68.0
- Percentile: 88.0
- Lexical Diversity: 1.52941
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15591605', '15117018', '15595107', '14996829', '14428927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8659412110996192
- 35 USC 102 Novelty (BERT): 0.634775625704634
- Combined Prediction Score: 0.8428246525601207
- Mean Citation Score: 556.90546
- Max Citation Score: 640.4448
- Similarity Product: 559.7621623386383

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test