PATENT CLAIM ANALYSIS

Application Number: 16354651
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["514", "005100"]

Abstract:
The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there althered profile considered particular useful in therapy.

Claim (Index 17):
A compound of formula (III)\n A-W\u2014B1-U\u2003\u2003(III) wherein A represent an albumin binding residue; B1 represents a hydrophilic spacer; W is a chemical group linking A and B1, and U represent a conjugating moiety wherein the conjugating moiety, U, a) comprises or consists of an aryl, an heteraryl, a substituted malimide or a pyrrolidine-2,5-dione, b) comprises D1-(CH 2 ) l6 -D2, wherein D1 and D2 are independently selected from \u2014O\u2014, \u2014N(R6)-, \u2014NC(O)R7- or a valence bond, wherein R6 and R7 independently represent hydrogen or C 1-6 -alkyl, c) comprises or consists of a leaving group, such as Cl, Br, I, \u2014OH, \u2014OS(O) 2 Me, \u2014OS(O) 2 CF 3 , \u2014OTs, d) comprises or consists of an allyl amine (H 2 C\u2550CH\u2014CH 2 \u2014NH 2 ), or e) comprises an amine.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 99.0
- Lexical Diversity: 1.31818
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13522390', '14132919', '13144757', '13574128', '12990101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.787108272129624
- 35 USC 102 Novelty (BERT): 0.6174132992530986
- Combined Prediction Score: 0.7701387748419715
- Mean Citation Score: 456.2411679999999
- Max Citation Score: 676.3252
- Similarity Product: 459.0451935234546

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test