PATENT CLAIM ANALYSIS

Application Number: 15522969
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-04
Patent Classification: ["514", "252030"]

Abstract:
Provided herein are compounds and methods for treating a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease. Provided herein are compositions and methods for treating a disorder associated with aberrant Aβ peptide levels, including AD. Provided herein are compounds of Formula (A) or a pharmaceutically acceptable salt thereof, wherein, L′ is selected from the group consisting of C(O), C(R1)(R2), substituted or unsubstituted —C2-6 alkylene-, and substituted or unsubstituted —C3-6 cycloalkylene.

Claim (Index 9):
The compound of any one of  claim 1  or  3 - 6 , wherein Z is selected from the group consisting of fluoro, OH, methoxy, methyl, ethyl, isopropyl, tert-butyl, phenyl, fluorophenyl, chlorophenyl, methoxyphenyl, (trifluoromethyl)phenyl, difluorophenyl, methylphenyl, bis(trifluoromethyl)phenyl, 4-fluoro-3-methoxyphenyl, 4-fluoro-2-methoxyphenyl, 4-fluoro-3-methylphenyl, 4-fluoro-2-methylphenyl, trifluorophenyl, 4-fluoro-3-(trifluoromethyl)phenyl, 4-fluoro-2-(trifluoromethyl)phenyl, 2-chloro-4-fluorophenyl, cyclohexyl, pyridinyl, fluoropyridinyl, benzo[d]oxazolyl, naphthyl, fluoronaphthyl, cyclopropyl, cyclopentyl, hydroxyphenyl, aminophenyl, 4-trifluoromethyl-3-(methoxy)phenyl, 4-trifluoromethyl-3-(fluoro)phenyl, oxazol-2-yl, pyrazole-5-yl, oxazol-5-yl, oxazol-4-yl, isoxazol-5-yl, isoxazol-3-yl, 1,3,4-oxadiazol-2-yl, 1,2,4-oxadiazol-5-yl, isoxazol-3-one-5-yl, 2-fluoro-3-chlorophenyl, 2-fluoro-3-(trifluoromethyl)phenyl, 3-fluoro-2-methylphenyl, difluoropyridinyl, difluorophenyl, 2-fluoro-5-methylphenyl, and 3-chloro-5-fluorophenyl.\n or L 1  is absent and Z is selected from the group consisting of cyclopropyl, cyclopentyl, cyclohexyl, 4,4,-difluorocyclohexyl, 4-trifluoromethylcyclohexyl, 2-ethyl-4,5,6,7-tetrahydro-2H-isoindolyl, 3,3-difluorocyclopentyl, 3,3-difluorocyclohexyl, 3-trifluoromethylcyclohexyl, 6-fluoro-1H-indol-3-yl, and 6-fluoro-1-methyl-1H-indol-3-yl.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 91.0
- Lexical Diversity: 1.77358
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15421258', '14775483', '14992396', '14550528', '13806692']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8085105286841756
- 35 USC 102 Novelty (BERT): 0.5417381578133534
- Combined Prediction Score: 0.7818332915970934
- Mean Citation Score: 364.897392
- Max Citation Score: 378.66806
- Similarity Product: 287.10420074605946

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test