PATENT CLAIM ANALYSIS

Application Number: 15999117
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["424", "001890"]

Abstract:
Provided herein are monoacylglycerol lipase (MGLL) occupancy probes comprising a MGLL inhibitor containing a positron emission tomography (PET) tracer radionuclide. Also provided are methods of assessing MGLL enzyme occupancy of a MGLL inhibitor using the radiolabeled occupancy probes described herein.

Claim (Index 15):
The radiolabeled MGLL occupancy probe of any one of  claims 6 - 14 , wherein R a  and R b , together with the nitrogen to which they are attached, form a 4-6 membered saturated heterocyclic ring, which may have an additional heteroatom selected from O, S, and N, wherein the 4-6 membered saturated heterocyclic ring is optionally substituted by one or more substituents selected from the group consisting of halogen, cyano, oxo, C 1-6 alkyl, C 1-6 haloalkyl, \u2014S(O) w \u2014C 1-6 alkyl (where w is 0, 1, or 2), hydroxyl, \u2014C(O)\u2014C 1-6 alkyl, \u2014NH 2 , and \u2014NH\u2014C(O)\u2014C 1-6 alkyl.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 96.0
- Lexical Diversity: 1.48387
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13043956', '13479826', '14003547', '14764426', '13391402']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.77116217665071
- 35 USC 102 Novelty (BERT): 0.4990759686620259
- Combined Prediction Score: 0.7439535558518416
- Mean Citation Score: 262.048626
- Max Citation Score: 265.28232
- Similarity Product: 202.99628158555987

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test