PATENT CLAIM ANALYSIS

Application Number: 16083485
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["549", "408000"]

Abstract:
Provided are a 4-sulfur pentafluoride phenol compound and a preparation method therefor, and a preparation method for a sulfur pentafluoride substituted benzopyran compound. According to the present invention, sulfur pentafluoride salicylaldehyde with multiple substituent groups is synthesized through a plurality of steps by using sulfur pentafluoride phenol as a raw material, and then the sulfur pentafluoride substituted benzopyran compound is synthesized on this basis. The method is simple and convenient, and low in cost; overcomes the defects that, at present, the number of types of sulfur pentafluoride phenols is small, and the synthesis of various sulfur pentafluoride substituted benzopyran compounds cannot be met; and has wide industrial application prospects.

Claim (Index 26):
The preparation method according to  claim 25 ,\n wherein the chloroformate in step (1) is any one or a combination of at least two selected from a group consisting of methyl chloroformate, ethyl chloroformate, propyl chloroformate and butyl chloroformate, wherein the molar ratio of compound II to chloroformate in step (1) is from 1:2 to 1:3; wherein the molar ratio of compound II to sodium borohydride in step (1) is from 1:8 to 1:10; wherein the solvent used in the reaction of compound II with chloroformate in step (1) is dichloromethane and/or chloroform; wherein the reaction of compound II with chloroformate in step (1) is carried out in the presence of a weakly basic substance; wherein the molar ratio of compound II to the weakly basic substance is from 1:2 to 1:10; wherein the temperature for the reaction between compound II and chloroformate in step (1) is from 0\u00b0 C. to 30\u00b0 C.; wherein the time for the reaction between compound II and chloroformate in step (1) is from 1 to 5 hours; wherein the temperature for the reaction between compound II and sodium borohydride in step (1) is from 0\u00b0 C. to 30\u00b0 C.; wherein the time for the reaction between compound II and sodium borohydride in step (1) is from 1 to 5 hours; wherein the acid solution in step (2) is any one or a combination of at least two selected from a group consisting of trifluoroacetic acid, polyphosphoric acid and glacial acetic acid; wherein the molar ratio of compound III(a) to hexamethylenetetramine in step (2) is from 1:1.2 to 1:2; wherein the amount of the acid solution used in step (2) is from 10 to 30 mL on the basis of 1 g of compound III(a); wherein the reaction temperature in step (2) is from 60\u00b0 C. to 100\u00b0 C.; wherein the reaction time in step (2) is from 8 to 48 hours; wherein the molar ratio of compound IV to ethyl 4,4,4-trifluorocrotonate in step (3) is from 1:1.2 to 1:10; wherein the weak base in step (3) is any one or a combination of at least two selected from a group consisting of triethylamine, potassium carbonate, cesium carbonate and cesium fluoride; wherein the amount of the weak base used in step (3) is from 10 to 20 mL on the basis of 1 g of compound IV; wherein the solvent used in step (3) is any one or a combination of at least two selected from a group consisting of triethylamine, tetrahydrofuran, N,N-dimethylformamide and dimethyl sulfoxide; wherein the reaction temperature in step (3) is from 80\u00b0 C. to 120\u00b0 C.; wherein the reaction time in step (3) is from 10 to 72 hours; wherein the base in step (4) is any one or a combination of at least two selected from a group consisting of potassium hydroxide, sodium hydroxide and lithium hydroxide; wherein the molar ratio of compound V to the base in step (4) is from 1:10 to 1:20; wherein the temperature for the hydrolysis with a base in step (4) is from 20\u00b0 C. to 30\u00b0 C.; wherein the time for the hydrolysis with a base in step (4) is from 1 to 5 hours; wherein the acid in step (4) is hydrochloric acid and/or sulfuric acid.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 97.0
- Lexical Diversity: 1.76812
- Patent Class: 549.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15572160', '12053775', '12562805', '13520023', '12882469']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7577729578119304
- 35 USC 102 Novelty (BERT): 0.4931543448837202
- Combined Prediction Score: 0.7313110965191094
- Mean Citation Score: 230.615778
- Max Citation Score: 242.2043
- Similarity Product: 184.0735333100081

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test