PATENT CLAIM ANALYSIS

Application Number: 15882455
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["424", "184100"]

Abstract:
The present invention relates to (isolated) recombinant proteins, also referred to as improved MAT (iMAT) molecules, comprising at least one translocation module, at least one targeting module and at least one antigen module, wherein at least one cysteine residue is substituted with a different amino acid residue. Such iMAT molecules are useful specifically as vaccines, e.g., for therapy and/or prevention of allergies and/or infectious diseases and/or prevention of transmission of infectious diseases in equines. The present invention further relates to nucleic acids encoding such iMAT molecules, corresponding vectors and primary cells or cell lines.

Claim (Index 3):
A method of preventing and/or treatment of one or more infectious diseases in equines, comprising administering a pharmaceutically effective amount of the iMAT molecule comprising:\n i. at least one first module being an amino acid sequence allowing the translocation of the iMAT molecule from the extracellular space into the interior of cells, ii. at least one second module being an amino acid sequence allowing species-specific intracellular targeting of the iMAT molecule to the cell organelles which are involved in the processing of antigens and/or the loading of MHC molecules with antigens, and iii. at least one third module as antigen module being an amino acid sequence derived from at least one full or partial epitope of at least one antigen, determining the specificity of an immune response modulated by such iMAT molecule, iv. wherein in the antigen module(s) at least one cysteine residue is substituted with a different amino acid residue.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 86.0
- Lexical Diversity: 1.61194
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15520676', '11474180', '11601687', '11886577', '11102883']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6374016100920762
- 35 USC 102 Novelty (BERT): 0.5053598006970078
- Combined Prediction Score: 0.6241974291525694
- Mean Citation Score: 226.108516
- Max Citation Score: 243.88051
- Similarity Product: 173.3376469726723

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test