PATENT CLAIM ANALYSIS

Application Number: 15957474
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["424", "400000"]

Abstract:
Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

Claim (Index 73):
The drug delivery system or pharmaceutically acceptable salt of  claim 69 , wherein D comprises one or more biologically active peptides selected from C-type natriuretic peptide (CNP), atrial natriuretic peptide (ANP), exendin-4, insulin, adrenocorticotropic hormone, adrenomedullin, adropin, \u03c9-agatoxin, agouti-related protein, angiotensin(s), apelin 12, apelin 13, apelin 36, or derivatives thereof, bradykinin, calcitonin, cocaine- and amphetamine-regulated transcript (CART), corticotropin releasing factor (CRF), \u03b1-defensins, \u03b2-defensins, delta sleep-inducing peptide (DSIP), elastase-specific inhibitor (Elafin), endokinins, endomorphins, endorphins, endothelins, exendin, fibronectin active fragment, galanin, galanin-like peptide, big gastrin, gastrin I, gastrin related peptide, gastric inhibitory polypeptide, gastrin releasing peptide, ghrelin, des-acyl ghrelin, glucagon, glucagon-like peptide, growth hormone releasing factor,  Grammostola spatulata  GsMTx-4, guangxitoxin-1E, guanylin, hepcidin 1, hepcidin/LEAP-I, histatin 5, human growth hormone, humanin, huwentoxin, iberiotoxin, imperatoxin A, insulin like growth factors, intermedin, IRL 1620, joining peptide, kaliotoxin, kisspeptins, kurtoxin, lipotropin, lipotropin, liver-cell growth factor, liver-expressed antimicrobial peptide 2, luteinizing hormone releasing hormone, lysenin, LL-37, margatoxin, mastoparan, mast cell degranulating peptide, melanin-concentrating hormone, melanocyte stimulating hormone, MSH-release inhibiting factor, midkine, molluscan cardioexcitatory neuropeptide, morphine tolerance peptide, motilin, muscarinic toxins, neuroendocrine regulatory peptide-2, neurokinin A, neurokinin B, neuromedins, neuronostatin-13, neuropeptides, neurotensin, neurotoxin NSTX-3, nocistatin, nociceptin, obestatin, opioid peptides (enkephalins, endorphins, BAM-12P, casomorphin, dynorphins, endomorphins, neo-endorphins, nociceptin), orexin-A/-B, orphanin, osteocalci, oxytocin, pancreastatin, parathyroid hormone, parathyroid hormone related protein, peptide 234, peptide histidine-methionine, peptide T, peptide YY, Physalaemin, pituitary adenylate cyclase activating polypeptides, platelet factor-4, plectasin, pleiotrophin, proadrenomedullin, prolactin-releasing peptide, psalmotoxin 1, purotoxin-1, pyroglutamylated RFamide peptide, renin, RFamide-related peptide-1, RFamide-related peptide-3, salusin-\u03b1/\u03b2, sarafotoxins, schizophrenia related peptide, scyllatoxin, secretin, serelaxin, serum thymic factor, sodium potassium ATPase inhibitor-1, somatostatin, stichodactyla toxin, substance K, stresscopin, stresscopin-related peptide, substance P, tachykinins, tarantula SNX-482, tarantula ProTx-I, tarantula ProTx-II, tertiapin, tityustoxin Ka, thyrotropin releasing hormone, tuftsin, uroguanylin, uroguanylin isomer A or B, urocortin, urocortin II, urotensin II, urotensin II-related peptide, vasoactive intestinal peptide, vasopressin, vasotocin, virus replication inhibiting peptide, xenin, or combinations thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 1.43902
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11150522', '13397195', '14849270', '14512059', '13984762']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7231170253678479
- 35 USC 102 Novelty (BERT): 0.5127699777502795
- Combined Prediction Score: 0.7020823206060911
- Mean Citation Score: 264.81159
- Max Citation Score: 277.69498
- Similarity Product: 212.0550514277637

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test