PATENT CLAIM ANALYSIS

Application Number: 16146644
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "278000"]

Abstract:
The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R 1  and R 2  are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Claim (Index 24):
The method of  claim 20 , wherein R 1  is phenyl optionally substituted with 1 to 3 substituents selected from the group consisting of halo, hydroxy, C 1 -C 5  alkyl, C 1 -C 5  alkoxy, C 1 -C 5  alkylthio, amino, di(C 1 -C 5  alkyl)amino, cyano, formyl, halo-C 1 -C 5  alkyl, hydroxy-C 1 -C 5  alkyl, C 1 -C 5  alkoxy-C 1 -C 5  alkyl, carbamoyloxy-C 1 -C 5  alkyl and C 1 -C 5  alkyl-C(O)O\u2014C 1 -C 5  alkyl; or 5- to 10-membered, unsaturated heterocyclyl having 1-3 heteroatoms selected from the group consisting of N, O and S, which is optionally substituted with 1 to 3 substituents selected from the group consisting of halo, hydroxy, C 1 -C 5  alkyl, C 1 -C 5  alkoxy and halo-C 1 -C 5  alkyl.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 97.0
- Lexical Diversity: 1.63636
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15664633', '15053569', '13516985', '15094687', '15962333']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.802613491607305
- 35 USC 102 Novelty (BERT): 0.6361810304078812
- Combined Prediction Score: 0.7859702454873626
- Mean Citation Score: 412.195834
- Max Citation Score: 594.1443
- Similarity Product: 552.8342552633108

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test