PATENT CLAIM ANALYSIS

Application Number: 16081543
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-03
Patent Classification: ["514", "415000"]

Abstract:
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for the treatment of lysine (K)-specific demethylase 1A (LSD1)-mediated diseases or disorders: wherein R 1 , R 2 , R 3 , R 4 , R 5 , and R 6  are as defined herein.

Claim (Index 1):
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is independently selected from: C 1 -C 6  alkyl substituted with one to two R a , C 2 -C 6  alkenyl substituted with one to two R a , \u2014(CH) n \u2014(C 3 -C 6  cycloalkyl substituted with one to two R d ), \u2014(CH) n -(phenyl substituted with zero to three R b ), \u2014(CH) n -(6-membered heteroaryl comprising carbon atoms and 1-2 heteroatoms selected from N and NR a , where said heteroaryl is substituted with zero to three R b ), \n R 2  is independently selected from: H, halogen and C 1 -C 4  alkyl; R 3  is independently selected from: R 4  is independently selected from: H, halogen and C 1 -C 4  alkyl; R 5  is independently selected from: H, halogen, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl and C 3 -C 6  cycloalkyl; R 6  is independently selected from: H, halogen and C 1 -C 4  alkyl; R 7  is, at each occurrence, independently selected from: NH 2 , NH(C 1 -C 4  alkyl), and NHCO(C 1 -C 4  alkyl); R 8  is, at each occurrence, independently selected from: H, halogen, C 1 -C 4  alkyl, and C 1 -C 4  haloalkyl; Y is, at each occurrence, independently selected from: CH and N; W is independently selected from: O and NH; R a  is independently selected from: OH, C 1 -C 4  alkoxy, CO 2 (C 1 -C 4  alkyl), CONR e R f , and NHR e ; R b  is independently selected from: halogen, C1-C4 haloalkoxy, OH, CN, CO 2 (C 1 -C 4  alkyl), CONR e R f , NHR e  C 1 -C 4  alkyl substituted with zero to one R c , and C 1 -C 4  alkoxy substituted with zero to one R c ; R c  is independently selected from: OH, C 1 -C 4  alkoxy, CO 2 (C 1 -C 4  alkyl), CONR e R f , and NHR e ; R d  is independently selected from: OH, \u2550O, and NH(C 1 -C 4  alkyl); R e  is independently selected from: H, C 1 -C 4  alkyl, and CO(C 1 -C 4  alkyl); R f  is independently selected from: H and C 1 -C 4  alkyl; m is independently selected from: 1 and 2; n, at each occurrence, is independently selected from: 0 and 1; and q is independently selected from: 1, 2 and 3.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 96.0
- Lexical Diversity: 1.34
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16012468', '14977273', '16311575', '15538348', '16311621']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7477922558860043
- 35 USC 102 Novelty (BERT): 0.5576276861679917
- Combined Prediction Score: 0.7287757989142031
- Mean Citation Score: 354.638328
- Max Citation Score: 418.77243
- Similarity Product: 343.89599990968645

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test