PATENT CLAIM ANALYSIS

Application Number: 16298521
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "317100"]

Abstract:
Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (IA) are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having IA.

Claim (Index 5):
A method of detecting the presence of an  Aspergillus fumigatus, A. terreus , or  A. calidoustus  infection in a subject, the method comprising:\n obtaining a sample comprising breath of a subject, or headspace from a culture suspected of comprising  Aspergillus  isolated from a subject; determining the presence of one, two, three, or more, e.g., all, of the VOCs selected from the group consisting of camphene, \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, trans-geranylacetone, elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, 1,5,9-trimethyl cyclododecatriene, 9-decene-2-one and beta-sesquiphellandrene in the sample, wherein:\n the presence of one, two, three, or more, e.g., all, of camphene, \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, and trans-geranylacetone indicates the presence of an  A. fumigatus  infection; \n the presence of one, two, three, or more, e.g., all, of elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, and 1,5,9-trimethyl cyclododecatriene indicates the presence of an  A. terreus  infection; and \n the presence of one or both of 9-decene-2-one and beta-sesquiphellandrene indicates the presence of an  A. calidoustus  infection in the subject.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.27778
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316062', '14426678', '15023640', '14628125', '13261101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5977027813560767
- 35 USC 102 Novelty (BERT): 0.6676419032757331
- Combined Prediction Score: 0.6046966935480423
- Mean Citation Score: 408.262416
- Max Citation Score: 777.9191
- Similarity Product: 627.4414275654316

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test