PATENT CLAIM ANALYSIS

Application Number: 15948202
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["424", "450000"]

Abstract:
Provided herein are methods and compositions for the delivery of bioactive compounds to a cell, tissue, or physiological site. The compositions comprise delivery system complexes comprising liposomes encapsulating a biodegradable ionic precipitate having incorporated therein a bioactive compound and delivery system complexes comprising a biodegradable ionic precipitate ionically bound to a surrounding lipid bilayer, wherein the biodegradable ionic precipitate comprises a bioactive compound. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering the delivery system complexes comprising bioactive compounds that have therapeutic activity against the disease or unwanted condition to the subject.

Claim (Index 26):
A delivery system complex comprising a biodegradable nanoprecipitate, wherein said biodegradable nanoprecipitate comprises a bioactive compound, wherein said biodegradable nanoprecipitate is encapsulated by a lipid bilayer membrane; wherein\n said lipid bilayer membrane comprises an inner leaflet and an outer leaflet; wherein\n said inner leaflet comprises a first lipid, wherein said first lipid comprises DOPA; and \n said outer leaflet comprises a second lipid, wherein said second lipid comprises lipids selected from the group consisting of DOPC, DOTAP, PEG, and a lipid-PEG conjugate; \n said bioactive compound comprises an anticancer drug; and said lipid bilayer membrane is asymmetric.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 91.0
- Lexical Diversity: 1.98246
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13388538', '12993421', '15320903', '09553639', '12852362']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6720936533629548
- 35 USC 102 Novelty (BERT): 0.620959754030682
- Combined Prediction Score: 0.6669802634297275
- Mean Citation Score: 322.708076
- Max Citation Score: 589.49854
- Similarity Product: 494.1200848169768

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test