PATENT CLAIM ANALYSIS

Application Number: 16129268
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["540", "462000"]

Abstract:
Disclosed is a method of preparing an amino acid ester of maytansinol by reacting maytansinol with an N-carboxyanhydride of an amino acid (NCA) in the presence of a drying agent. Also disclosed is an improved method of preparing an amino acid ester of maytansinol in which a nucleophile is added to the reaction mixture after completion of the reaction between maytansinol and an N-carboxyanhydride of an amino acid.

Claim (Index 6):
The method of any one of  claims 1 - 5 , wherein further comprising contacting the reaction mixture after the reaction of maytansinol and the N-carboxyanhydride with an aqueous solution containing bicarbonate or carbonate or contacting the reaction mixture with a metal scavenger.

Metadata:
- Claim Count in Document: 107.0
- Percentile: 97.0
- Lexical Diversity: 1.94595
- Patent Class: 540.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14037657', '14660050', '15708346', '15269163', '11500378']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6941801762698713
- 35 USC 102 Novelty (BERT): 0.5814771297084123
- Combined Prediction Score: 0.6829098716137254
- Mean Citation Score: 404.595818
- Max Citation Score: 470.679
- Similarity Product: 405.80611807340375

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test