PATENT CLAIM ANALYSIS

Application Number: 16052082
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["435", "200000"]

Abstract:
The present invention relates to enzyme compositions comprising a polypeptide having cellobiohydrolase II activity, a polypeptide having xylanase activity, and one or more cellulolytic proteins and their use in the degradation or conversion of cellulosic material.

Claim (Index 21):
An enzyme composition comprising a CEL6 polypeptide having cellobiohydrolase II activity, a GH10 polypeptide having xylanase activity, and one or more cellulolytic enzymes selected from the group consisting of an endoglucanase, a cellobiohydrolase, and a beta-glucosidase, wherein one or both of the CEL6 polypeptide having cellobiohydrolase II activity and the GH10 polypeptide having xylanase activity are foreign to the one or more cellulolytic enzymes; (b) fermenting the saccharified cellulosic material with one or more fermenting microorganisms; and (c) recovering the fermentation product from the fermentation;\n wherein the CEL6 polypeptide having cellobiohydrolase II activity is selected from the group consisting of: (a) a polypeptide having cellobiohydrolase II activity comprising an amino acid sequence having a sequence identity of at least 90% to amino acids 25 to 471 of SEQ ID NO: 26, amino acids 18 to 482 of SEQ ID NO: 30, amino acids 19 to 471 of SEQ ID NO: 32, amino acids 18 to 481 of SEQ ID NO: 34, or amino acids 18 to 477 of SEQ ID NO: 38; (b) a polypeptide having cellobiohydrolase II activity encoded by a polynucleotide that hybridizes under very high stringency conditions with nucleotides 125 to 1465 of SEQ ID NO: 25, nucleotides 52 to 1809 of SEQ ID NO: 29, nucleotides 107 to 1465 of SEQ ID NO: 31, nucleotides 52 to 1443 of SEQ ID NO: 33, or nucleotides 15 to 1731 of SEQ ID NO: 37, or the full-length complement thereof, wherein the very high stringency conditions are defined as prehybridization and hybridization at 42\u00b0 C. in 5\u00d7SSPE, 0.3% SDS, 200 \u03bcg/ml sheared and denatured salmon sperm DNA, and 50% formamide for 12 to 24 hours and washing three times each for 15 minutes using 2\u00d7SSC, 0.2% SDS at 70\u00b0 C.; (c) a polypeptide having cellobiohydrolase II activity encoded by a polynucleotide comprising a nucleotide sequence having a sequence identity to nucleotides 125 to 1465 of SEQ ID NO: 25, nucleotides 52 to 1809 of SEQ ID NO: 29, nucleotides 107 to 1465 of SEQ ID NO: 31, nucleotides 52 to 1443 of SEQ ID NO: 33, or nucleotides 15 to 1731 of SEQ ID NO: 37 of at least 90%; and (d) a polypeptide having cellobiohydrolase II activity comprising amino acids 25 to 471 of SEQ ID NO: 26, amino acids 18 to 482 of SEQ ID NO: 30, amino acids 19 to 471 of SEQ ID NO: 32, amino acids 18 to 481 of SEQ ID NO: 34, or amino acids 18 to 477 of SEQ ID NO: 38; and wherein the GH10 polypeptide having xylanase activity is selected from the group consisting of: (a) a polypeptide having xylanase activity comprising an amino acid sequence having a sequence identity of at least 90% to amino acids 20 to 369 of SEQ ID NO: 72, amino acids 19 to 414 of SEQ ID NO: 74, amino acids 18 to 364 of SEQ ID NO: 76, amino acids 20 to 323 of SEQ ID NO: 78, or amino acids 20 to 397 of SEQ ID NO: 80; (b) a polypeptide having xylanase activity encoded by a polynucleotide that hybridizes under very high stringency conditions with nucleotides 58 to 1107 of SEQ ID NO: 71, nucleotides 55 to 1242 of SEQ ID NO: 73, nucleotides 52 to 1145 of SEQ ID NO: 75, nucleotides 58 to 1400 of SEQ ID NO: 77, or nucleotides 107 to 1415 of SEQ ID NO: 79, or the full-length complement thereof, wherein the very high stringency conditions are defined as prehybridization and hybridization at 42\u00b0 C. in 5\u00d7SSPE, 0.3% SDS, 200 \u03bcg/ml sheared and denatured salmon sperm DNA, and 50% formamide for 12 to 24 hours and washing three times each for 15 minutes using 2\u00d7SSC, 0.2% SDS at 70\u00b0 C.; (c) a polypeptide having xylanase activity encoded by a polynucleotide comprising a nucleotide sequence having a sequence identity of at least 90% to nucleotides 58 to 1107 of SEQ ID NO: 71, nucleotides 55 to 1242 of SEQ ID NO: 73, nucleotides 52 to 1145 of SEQ ID NO: 75, nucleotides 58 to 1400 of SEQ ID NO: 77, or nucleotides 107 to 1415 of SEQ ID NO: 79; and (d) a polypeptide having xylanase activity comprising amino acids 20 to 369 of SEQ ID NO: 72, amino acids 19 to 414 of SEQ ID NO: 74, amino acids 18 to 364 of SEQ ID NO: 76, amino acids 20 to 323 of SEQ ID NO: 78, or amino acids 20 to 397 of SEQ ID NO: 80; wherein the one or more cellulolytic enzymes comprise a beta-glucosidase, a  Trichoderma reesei  cellobiohydrolase I (CEL7A), a  Trichoderma reesei  cellobiohydrolase II (CEL6A), and a  Trichoderma reesei  endoglucanase I (CEL7B).

Metadata:
- Claim Count in Document: 47.0
- Percentile: 96.0
- Lexical Diversity: 1.21875
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14849204', '15591935', '14248039', '12612401', '14010199']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.687621139549691
- 35 USC 102 Novelty (BERT): 0.6478056284748467
- Combined Prediction Score: 0.6836395884422065
- Mean Citation Score: 574.4875860000002
- Max Citation Score: 618.9143
- Similarity Product: 600.9816578108132

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test