PATENT CLAIM ANALYSIS

Application Number: 16212582
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["544", "279000"]

Abstract:
The present application provides a compound of formula (I) or a salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A, G, M, Q and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders.

Claim (Index 30):
The method according to  claim 12  wherein the compound of formula I is selected from the group consisting of: Structure Name (S)-N*1*-[7-(3-Methoxy-prop-1- ynyl)-2-pyridin-4-yl-thieno[3,2- d]pyrimidin-4-yl]-3-phenyl- propane-1,2-diamine   4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-(3-fluoro-pyridin- 4-yl)-thieno[3,2-d]pyrimidin-7-yl]- but-3-yn-1-ol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-6-methyl-2-pyridin- 4-yl-thieno[3,2-d]pyrimidin-7-yl]- 2-methyl-but-3-yn-2-ol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-6-tert-butyl-2- pyridin-4-yl-thieno[3,2- d]pyrimidin-7-yl]-2-methyl-but-3- yn-2-ol   3-[4-((S)-2-Amino-3-phenyl- propylamino)-2-(3-fluoro-pyridin- 4-yl)-thieno[3,2-d]pyrimidin-7-yl]- prop-2-yn-1-ol   1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-(3-fluoro-pyridin- 4-yl)-thieno[3,2-d]pyrimidin-7- ylethynyl]-cyclobutanol   (S)-4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-(3-fluoro-pyridin- 4-yl)-thieno[3,2-d]pyrimidin-7-yl]- but-3-yn-2-ol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-(3-fluoro-pyridin- 4-yl)-thieno[3,2-d]pyrimidin-7-yl]- 2-methyl-but-3-yn-2-ol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-2- methyl-but-3-yn-2-ol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-but-3- yn-2-ol   3-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-prop- 2-yn-1-ol   S)-1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-pent- 1-yn-3-ol   (S)-1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]primidin-7-yl]-4- methyl-hept-1-yn-3-ol   (S)-1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-3- methyl-pent-1-yn-3-ol   (S)-1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-3,4- dimethyl-pent-1-yn-3-ol   1-[4-(2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-3- ethyl-pent-1-yn-3-ol   (S)-1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-hex-1- yn-3-ol   1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7- ylethynyl]-cyclopentanol   4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-but-3- yn-1-ol   1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7- ylethynyl]-cyclopropanol   (S)-4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-but-3- yn-2-ol   (R)-4-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-but-3- yn-2-ol   5-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-pent- 4-yn-1-ol   5-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-pent- 4-yn-2-ol   5-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-2- methyl-pent-4-yn-2-ol   1-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7- ylethynyl]-cyclobutanol   (S)-5-[4-((S)-2-Amino-3-phenyl- propylamino)-2-pyridin-4-yl- thieno[3,2-d]pyrimidin-7-yl]-pent- 4-yn-2-ol   (S)-N*1*-[7-((R)-3-Fluoro-but-1- ynyl)-2-pyridin-4-yl-thieno[3,2- d]pyrimidin-4-yl]-3-phenyl- propane-1,2-diamine   (S)-N*1*-[7-(3-Fluoro-prop-1- ynyl)-2-pyridin-4-yl-thieno[3,2- d]pyrimidin-4-yl]-3-phenyl- propane-1,2-diamine   (S)-N*1*-[7-(4-Fluoro-but-1-ynyl)- 2-pyridin-4-yl-thieno[3,2- d]pyrimidine

Metadata:
- Claim Count in Document: 59.0
- Percentile: 98.0
- Lexical Diversity: 1.57447
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15417191', '14668022', '14285007', '14975605', '14038915']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8275562113019203
- 35 USC 102 Novelty (BERT): 0.6089680524533472
- Combined Prediction Score: 0.805697395417063
- Mean Citation Score: 464.299616
- Max Citation Score: 613.6288
- Similarity Product: 463.89483996925344

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test