PATENT CLAIM ANALYSIS

Application Number: 16073809
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["544", "262000"]

Abstract:
The present invention relates to a process for the preparation of 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one or Ibrutinib of Formula (I). The present invention further relates to a process for the preparation highly pure 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one or Ibrutinib(I)

Claim (Index 5):
A process for the preparation of Ibrutinib (I) according to  claim 1 , wherein step d) is carried out in presence of a coupling reagent selected from 1-Ethyl-3-(3-dimethylaminopropyl)carbodimide (EDCI), DCC, HOBt, HATU, TATU, CDI or in combination thereof.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 95.0
- Lexical Diversity: 2.33333
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16074505', '13859569', '14418484', '13908949', '14374788']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7430085445519685
- 35 USC 102 Novelty (BERT): 0.5604473562367728
- Combined Prediction Score: 0.724752425720449
- Mean Citation Score: 379.26753
- Max Citation Score: 448.23163
- Similarity Product: 319.2162137412716

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test