PATENT CLAIM ANALYSIS

Application Number: 16287771
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-08
Patent Classification: ["549", "408000"]

Abstract:
The present invention provides compounds that modulate the interaction of TCR with Nck, compositions thereof, and methods of treatment using the same.

Claim (Index 1):
A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R 1  is R, halogen, \u2014CN, \u2014OR, \u2014NHR, or \u2014N(R) 2 ; R 2  is R, halogen, \u2014C(O)N(R) 2 , or \u2014N(R) 2 ; R 3  is hydrogen or an electron withdrawing group; each R is independently hydrogen or an optionally substituted group selected from C 1-6  aliphatic, a 3-8 member saturated or partially unsaturated monocyclic carbocyclic ring, phenyl, a 4-8 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered monocyclic heteroaromatic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur,\n or two R on the same nitrogen are taken together with their intervening atoms to form an optionally substituted 5-6 membered heterocyclic ring having 0-1 heteroatoms in addition to the nitrogen attached thereto wherein such heteroatom is oxygen, nitrogen, or sulfur; \n L 1  is a covalent bond or a C 1-4  bivalent straight or branched saturated or unsaturated hydrocarbon chain wherein 1-2 methylene units of the chain are independently and optionally replaced with \u2014O\u2014, \u2014C(O)\u2014, \u2014C(O)O\u2014, \u2014OC(O)\u2014, \u2014C(S)\u2014, \u2014C(R) 2 \u2014, \u2014CH(R)\u2014, \u2014C(F) 2 \u2014, \u2014N(R)\u2014, \u2014C(O)N(R)\u2014, \u2014RNC(O)\u2014, \u2014OC(O)N(R)\u2014, \u2014N(R)C(O)N(R)\u2014, or -Cy-; L 2  is a covalent bond or a C 1-4  bivalent straight or branched saturated or unsaturated hydrocarbon chain wherein 1-2 methylene units of the chain are independently and optionally replaced with \u2014O\u2014, \u2014C(O)\u2014, \u2014C(O)O\u2014, \u2014OC(O)\u2014, \u2014C(S)\u2014, \u2014C(R) 2 \u2014, \u2014CH(R)\u2014, \u2014C(F) 2 \u2014, \u2014N(R)\u2014, \u2014C(O)N(R)\u2014, \u2014RNC(O)\u2014, \u2014OC(O)N(R)\u2014, or \u2014N(R)C(O)N(R)\u2014; and each Cy is independently a bivalent optionally substituted 3-8 membered saturated or partially unsaturated monocyclic carbocyclic ring, optionally substituted phenylene, an optionally substituted 4-8 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, an optionally substituted 5-6 membered monocyclic heteroaromatic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; wherein said compound is other than a compound selected from:

Metadata:
- Claim Count in Document: 37.0
- Percentile: 99.0
- Lexical Diversity: 1.13636
- Patent Class: 549.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11046664', '13873591', '13560131', '12670989', '13308612']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7597615688457828
- 35 USC 102 Novelty (BERT): 0.5011725434252811
- Combined Prediction Score: 0.7339026663037327
- Mean Citation Score: 260.24751000000003
- Max Citation Score: 261.19708
- Similarity Product: 189.74321605188845

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test