PATENT CLAIM ANALYSIS

Application Number: 15745461
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["548", "255000"]

Abstract:
The disclosure provides process developments and novel routes for the preparation of the NK-1 receptor antagonist, Compound (I) and intermediates in those routes.

Claim (Index 39):
The method of  claim 38 , wherein the mixture of lithiated 2-bromopyridine and Compound (VII) is allowed to react at a temperature of 65\u00b0 C. or less; and\n wherein the reaction is quenched by addition of methanol; \n the Compound (IIIa) is extracted by addition of aqueous HCl and t-butyl methyl ether; \n the organic phase is dried and concentrated; \n the residue is solubilized in IPA; and \n the Compound (IIIa) is crystallized by addition of heptane; and \n wherein the Compound (VII) is prepared according to a process comprising: \n combining morpholine, toluene, Compound (IX) \n and pyridine.

Metadata:
- Claim Count in Document: 108.0
- Percentile: 86.0
- Lexical Diversity: 1.125
- Patent Class: 548.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14853883', '14946137', '15355630', '15841828', '13889980']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6699253709415448
- 35 USC 102 Novelty (BERT): 0.5070102120458596
- Combined Prediction Score: 0.6536338550519764
- Mean Citation Score: 216.948504
- Max Citation Score: 220.2003
- Similarity Product: 139.33862486436368

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test