PATENT CLAIM ANALYSIS

Application Number: 16313956
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["546", "197000"]

Abstract:
Compounds of formula I, wherein R a  and R b  are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.

Claim (Index 3):
The compound according to  claim 1 , wherein;\n R a  and R b  form, together with the nitrogen atom to which they are attached, a 5 or 6 membered saturated or unsaturated heterocyclic ring, containing, in addition to the nitrogen atom to which R a  and R b  are attached, 0, 1 or 2 ring heteroatom(s) each independently selected from N, O and S, wherein said heterocyclic ring is substituted with 1 substituent R 1 , or said heterocyclic ring is substituted with 2 substituents R 1  and R 2 , or said heterocyclic ring is substituted with 3 substituents R 1 , R 2 , and R 3 , or said heterocyclic ring is substituted with 4 substituents R 1 , R 2 , R 3 , and R 4 , or said heterocyclic ring is substituted with 5 substituents R 1 , R 2 , R 3 , R 4  and R 5 ; R 1  is oxo, R 2  is oxo, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy(C 1 -C 6 )alkyl, (R 6 ) 2 N\u2014(C 1 -C 6 )alkyl, (R 6 ) 2 N\u2014(C\u2550O)\u2014(C 1 -C 6 )alkyl, (C 1 -C 6 )alkyl-(C\u2550O)\u2014NR 6 \u2014(C 1 -C 6 )alkyl, cyclo(C 3 -C 6 )alkyl, cyclo(C 3 -C 6 )alkyl(C 1 -C 6 )alkyl, phenyl, phenyl(C 1 -C 6 )alkyl, heterocyclyl, or heterocyclyl(C 1 -C 6 )alkyl, wherein said phenyl, cyclo(C 3 -C 6 )alkyl, or heterocyclyl is optionally substituted with 1 or 2 substituent(s) each independently being halogen, (C 1 -C 6 )alkoxy, or (C 1 -C 6 )alkyl-(C\u2550O); R 3  is oxo, (C 1 -C 6 )alkyl, or phenyl; R 4  is oxo or (C 1 -C 6 )alkyl; R 5  is (C 1 -C 6 )alkyl; or two of R 3 , R 4  and R 5 , both attached to the same carbon ring atom form, together with the carbon ring atom to which they are attached, a 3 membered unsubstituted carbocyclic ring; or two of R 1 , R 2 , R 3 , R 4  and R 5  attached to the adjacent carbon ring atoms form, together with the carbon ring atoms to which they are attached, a phenyl ring, a 3 to 6 membered saturated or unsaturated carbocyclic ring, or a 5 or 6 membered saturated or unsaturated heterocyclic ring containing 1 or 2 ring heteroatom(s) each independently selected from N and S, wherein said phenyl ring, carbocyclic ring, or heterocyclic ring is unsubstituted, or said phenyl ring, carbocyclic ring, or heterocyclic ring is substituted with 1 substituent R 7 , or said phenyl ring, carbocyclic ring, or heterocyclic ring is substituted with 2 substituents R 7  and R 8 ; R 6  is H or (C 1 -C 6 )alkyl; R 7  is halogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkyl-S\u2014, CN, or (C 1 -C 6 )alkyl-(C\u2550O)\u2014NR 6 \u2014(C 1 -C 6 )alkyl; R 8  is halogen or (C 1 -C 6 )alkoxy; or R 7  and R 8 , attached to the non-adjacent carbon ring atoms, form a bridge.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 98.0
- Lexical Diversity: 1.25
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12668918', '14192131', '13917745', '14747485', '14725683']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8078241107724085
- 35 USC 102 Novelty (BERT): 0.5289433400612304
- Combined Prediction Score: 0.7799360337012907
- Mean Citation Score: 313.98425400000013
- Max Citation Score: 358.68304
- Similarity Product: 254.58381673366543

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test