PATENT CLAIM ANALYSIS

Application Number: 15968692
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["514", "063000"]

Abstract:
The technical field of the invention is in pharmaceutical compounds and methods. In an aspect, the disclosure provides macrolide compounds suitable for use as antifungal agents, as well as methods for their use and compositions containing the same.

Claim (Index 1):
A method for treating a patient suffering from a fungal infection, the method comprising administering to the patient an effective amount of a composition comprising a compound of formula (I) wherein:\n \u201ca\u201d is a double bond that may be present provided that R 5a  is not present; \n R 1  is selected from alkyl, alkenyl, or is taken together with R 3  or R 3a  to form a cycle; \n R 3  and R 3a  are independently selected from \u2014H, and \u2014OH, or R 3  and R 3a  together form \u2550X, where X is selected from O, C, and N such that \u2550X and the carbon atom to which it is attached forms a carbonyl, oxime, substituted oxime, imine, substituted imine, hydrazone, substituted hydrazone, terminal olefin, or substituted olefin functional group, or wherein one of R 3  and R 3a  is \u2014H and the other is taken together with R 1  or R 5  or R 5a  to form a cycle; \n R 5  and R 5a  are independently selected from \u2014H, \u2014OH, or \u2014OTBS, or R 5  and R 5a  together form \u2550O, or one of R 5  and R 5a  is \u2014H and the other is taken together with R 3  or R 3a  to form a cycle; \n R 7  and R 7a  are independently selected from \u2014H, \u2014OH, \u2014NH 2 , alkoxy, alkylcarboxy, alkenylcarboxy, and substituted versions thereof, or R 7  and R 7a  together form \u2550Y, where Y is selected from O, and N such that \u2550Y and the carbon atom to which it is attached forms a carbonyl or oxime functional group; and \n R9 is selected from \u2014H and \u2014OH, \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.35484
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15207384', '14641232', '13579911', '13400031', '13400032']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.710434070105131
- 35 USC 102 Novelty (BERT): 0.4937190088735961
- Combined Prediction Score: 0.6887625639819777
- Mean Citation Score: 235.238242
- Max Citation Score: 255.36905
- Similarity Product: 225.9662023464143

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test