PATENT CLAIM ANALYSIS

Application Number: 15975423
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["424", "179100"]

Abstract:
The present disclosure relates to compounds of formula (I): RCG1-L-P  (I) wherein RCG1 represents a reactive chemical group being reactive towards a chemical group present on a polypeptide such as an antibody; P represents H, OH or an activated O; and L represents a specific linker. The disclosure also relates to cryptophycin payloads, as well as to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The disclosure also relates to the process for preparing these conjugates.

Claim (Index 20):
The conjugate of formula (V) according to  claim 17 , wherein:\n when RCG1 represents a N-hydroxysuccinimidyl ester, RCG2 represents a NH 2  group, or when RCG1 represents a maleimido function, a haloacetamido function, a chlorine atom or an activated disulfide, RCG2 represents a \u2014SH group, or when RCG1 represents a N 3  group, RCG2 represents a C\u2261CH group or an activated C\u2261C group such as a cyclooctyne moiety, or when RCG1 represents a OH or NH 2  group, RCG2 represents a carboxylic acid or amide function, or when RCG1 represents a SH group, RCG2 represents a maleimido function, a haloacetamido function or an activated disulfide function, or when RCG1 represents a C\u2261CH group or an activated C\u2261C group, RCG2 represents a N 3  group, or when RCG1 represents a O-alkyl hydroxylamine function or a Pictet-Spengler reaction substrate, RCG2 represents an aldehyde or ketone function.

Metadata:
- Claim Count in Document: 55.0
- Percentile: 93.0
- Lexical Diversity: 1.61667
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14069057', '15581749', '15280563', '14843520', '14818455']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7691743731839735
- 35 USC 102 Novelty (BERT): 0.5176097843060665
- Combined Prediction Score: 0.7440179142961829
- Mean Citation Score: 309.744996
- Max Citation Score: 313.26495
- Similarity Product: 232.57865102088155

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test