PATENT CLAIM ANALYSIS

Application Number: 15981849
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["514", "360000"]

Abstract:
This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors, R-isomers, and non-hydroxylated and/or non-chiral propanamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Claim (Index 34):
The method of  claim 25 , wherein Q 1 , Q 2 , Q 3  and Q 4  is hydrogen, CN, NO 2 , CF 3 , F, Cl, Br, I, NHCOOR, N(R) 2 , NHCOR, COR, or substituted or unsubstituted phenyl.

Metadata:
- Claim Count in Document: 68.0
- Percentile: 93.0
- Lexical Diversity: 1.56044
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15923668', '15620761', '15981636', '15222734', '15331777']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8796607835708088
- 35 USC 102 Novelty (BERT): 0.7307753338150057
- Combined Prediction Score: 0.8647722385952286
- Mean Citation Score: 746.166328
- Max Citation Score: 856.6156
- Similarity Product: 787.873453316474

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test