PATENT CLAIM ANALYSIS

Application Number: 15867283
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "006100"]

Abstract:
The invention relates to a kit for preparing a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a kit for preparing a library of template polynucleotides suitable for methylation analysis.

Claim (Index 33):
A kit for use in preparing a 5\u2032 and 3\u2032 modified library of template polynucleotide molecules comprising known sequences at their 5\u2032 and 3\u2032 ends, the kit comprising methylated adaptor polynucleotides and oligonucleotide primers capable of annealing to the methylated adaptor polynucleotides, wherein said methylated adaptor polynucleotides are forked universal adaptors comprising a region of double stranded nucleic acids and at least one region of single stranded nucleic acids; the forked universal adaptors are phosphorylated at the 5\u2032 end of the region of double stranded nucleic acids; all cytosine bases in the forked universal adaptors are methylated; and the at least one region of single stranded nucleic acids is capable of hybridizing to SEQ ID NO: 6.

Metadata:
- Claim Count in Document: 89.0
- Percentile: 86.0
- Lexical Diversity: 1.71429
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12069174', '12799172', '11486953', '15173447', '14022470']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7095084576998467
- 35 USC 102 Novelty (BERT): 0.6554403888746315
- Combined Prediction Score: 0.7041016508173252
- Mean Citation Score: 558.207276
- Max Citation Score: 749.13745
- Similarity Product: 605.1394754854531

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test