PATENT CLAIM ANALYSIS

Application Number: 16059270
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["546", "332000"]

Abstract:
The present invention relates to a compound represented by the general formula (I) (wherein the definition of each group has the same meaning as described in the specification). The compound is useful as preventive and/or therapeutic agent for KCNQ2-5 channel-related diseases.

Claim (Index 1):
A compound represented by general formula (1): wherein X 1  is (1) a nitrogen atom or (2) C\u2014R 6 ; X 2  is (1) a nitrogen atom or (2) C\u2014R 7 ; R 11  is (1) OR 1  or (2) NH 2 ; R 1  is (1) a hydrogen atom or (2) a C1-4 alkyl group; R 2  and R 3  are each independently (1) a hydrogen atom, or (2) a C1-4 alkyl group which may be substituted with halogen, where both R 2  and R 3  are not simultaneously a hydrogen atom; R 4 , R 5 , R 6 , and R 7  are each independently (1) a hydrogen atom, (2) halogen, (3) a C1-4 alkyl group which may be substituted with halogen, or (4) a C1-4 alkoxy group which may be substituted with halogen, where both R 4  and R 5  are not simultaneously a hydrogen atom; Y is (1) \u2014NH\u2014, (2) \u2014O\u2014, or (3) a bond; R 8  is (1) a hydrogen atom or (2) a C1-4 alkyl group which may be substituted with halogen or a hydroxy group; R 9  is (1) a ring A, (2) a C1-6 alkyl group, (3) a C2-6 alkenyl group, (4) a C2-6 alkynyl group, (5) \u2014C1-4 alkylene group-ring A, (6) \u2014C2-4 alkenylene group-ring A, (7) \u2014C2-4 alkynylene group-ring A, (8) -ring B-ring C, (9) -ring B\u2014C1-4 alkylene group-ring C, (10) -ring B\u2014C2-4 alkenylene group-ring C, (11) -ring B\u2014C2-4 alkynylene group-ring C, or (12) -ring B\u2014O-ring C, where the alkyl group, alkenyl group, alkynyl group, alkylene group, alkenylene group or alkynylene group each may be substituted with halogen or a hydroxy group; the ring A is (1) C3-8 cycloalkane, (2) 3- to 8-membered heterocycloalkane, (3) a C3-12 monocyclic or bicyclic unsaturated carbocyclic ring, or which may be partially saturated, or (4) 3- to 12-membered monocyclic or bicyclic unsaturated heterocycle including one to four heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom, or which may be partially saturated; ring B and ring C are each independently (1) C3-8 cycloalkane, (2) 3- to 8-membered heterocycloalkane, (3) a C3-7 monocyclic unsaturated carbocyclic ring, or which may be partially saturated, or (4) 3- to 7-membered monocyclic unsaturated heterocycle including one to three heteroatoms selected from an oxygen atom, a nitrogen atom and a sulfur atom, or which may be partially saturated; where the ring A, ring B and ring C each independently may be substituted with one to five R 10 , and when a plurality of R 10  is present, the plurality of R 10  may be the same as or different from each other; R 10  is (1) halogen, (2) a hydroxy group, (3) a cyano group, (4) a C1-6 alkyl group which may be substituted with halogen or a hydroxy group, (5) a C1-6 alkoxy group which may be substituted with halogen or a hydroxy group, or (6) an amino group which may be substituted with a C1-4 alkyl group or a C2-5 acyl group, excluding N-ethyl-N\u2032-[2-bromo-4-(hexafluoro-2-hydroxy-2-propyl)phenyl]urea, a salt thereof, a solvate thereof, or a cocrystal thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.23684
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15671428', '15515243', '16095374', '15034905', '13982052']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8288048213846382
- 35 USC 102 Novelty (BERT): 0.5919486872695997
- Combined Prediction Score: 0.8051192079731344
- Mean Citation Score: 415.088984
- Max Citation Score: 536.2969400000002
- Similarity Product: 446.8788477465751

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test