PATENT CLAIM ANALYSIS

Application Number: 16114463
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-07
Patent Classification: ["435", "007210"]

Abstract:
Newly identified mammalian taste-cell-specific G protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for identifying putative taste modulating compounds using such hetero-oligomeric complexes also described, as is a novel surface expression facilitating peptide useful for targeting integral plasma membrane proteins to the surface of a cell.

Claim (Index 1):
A method of screening for compounds that modulate sweet or umami taste signaling comprising:\n (i) contacting a human cell which co-expresses at least two different T1R receptors or polypeptides on its surface, wherein one of said T1R receptors or polypeptide comprises human T1R3, with a putative taste modulating compound; and (ii) measuring activity from the T1R receptors or polypeptides expressed on the cell surface wherein the expressed T1R receptors or polypeptides act as a hetero-oligomeric complex.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 96.0
- Lexical Diversity: 1.74194
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15264785', '12185392', '09897427', '13016887', '13357110']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6841981022805792
- 35 USC 102 Novelty (BERT): 0.626009265323789
- Combined Prediction Score: 0.6783792185849002
- Mean Citation Score: 536.3366219999998
- Max Citation Score: 582.6402
- Similarity Product: 545.4611701326371

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test