PATENT CLAIM ANALYSIS

Application Number: 16158361
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "284000"]

Abstract:
The present invention relates to novel 1,2,4-triazolo[4,3-a]pyridine compounds as positive allosteric modulators (PAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which mGluR2 subtype of metabotropic receptors is involved.

Claim (Index 24):
A method of treating a subject having a central nervous system disorder selected from the group consisting of schizophrenia, generalized anxiety disorder, bipolar disorder (I or II), migraine, behavioral and psychological symptoms of dementia, epilepsy or convulsive disorders, panic disorder, mixed anxiety and depression, and agoraphobia comprising administering to said subject a therapeutically effective amount of\n (a) a compound of Formula (I) or a stereochemically isomeric form thereof, wherein R 1  is selected from C 1-6 alkyl, (C 3-8 cycloalkyl)C 1-3 alkyl, and (C 1-3 alkyloxy)C 1-3 alkyl; or a pharmaceutically acceptable salt thereof; and\n (b) an mGluR2 orthosteric agonist, \n for simultaneous, separate or sequential administration.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 97.0
- Lexical Diversity: 1.54902
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15533798', '13319558', '13883906', '14215462', '13123984']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4495375057360743
- 35 USC 102 Novelty (BERT): 0.5725030412993499
- Combined Prediction Score: 0.4618340592924019
- Mean Citation Score: 400.662804
- Max Citation Score: 451.457
- Similarity Product: 360.4757410378456

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test