PATENT CLAIM ANALYSIS

Application Number: 15881231
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["514", "183000"]

Abstract:
The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Claim (Index 74):
A method of identifying a compound useful for treating melanoma or for inhibiting endothelial recruitment, cell invasion, or metastatic angiogenesis, comprising\n (i) obtaining a test cell expressing a reporter gene encoded by a nucleic acid operatively linked to a promoter of a marker gene selected from the group consisting of miR-199a-3p, miR-199a-5p, miR-1908, and CTGF.; (ii) exposing the test cell to a test compound; (iii) measuring the expression level of the reporter gene in the test cell; (iv) comparing the expression level with a control level; and (v) selecting the test compound as a candidate useful for treating melanoma or for inhibiting endothelial recruitment, cancer cell invasion, or metastatic angiogenesis, if the comparison indicates that the expression level is lower than the control level.

Metadata:
- Claim Count in Document: 143.0
- Percentile: 86.0
- Lexical Diversity: 1.22727
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15228643', '14486477', '15650480', '14486466', '14678628']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8699803485590532
- 35 USC 102 Novelty (BERT): 0.634998478519517
- Combined Prediction Score: 0.8464821615550996
- Mean Citation Score: 749.8811079999997
- Max Citation Score: 894.0029
- Similarity Product: 541.505350715363

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test