PATENT CLAIM ANALYSIS

Application Number: 15873255
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "313000"]

Abstract:
Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.

Claim (Index 1):
A compound having formula (I): including enantiomers, diastereomers, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, wherein: A is selected from the up consisting of Z 1  is selected from the group consisting of S, SO, and SO 2 ; Z 2  is selected from the group consisting of S, SO, and SO 2 ; Z 3  is selected from the group consisting of SH, SCOR 1 , SO 2 R 2 , and SO 3 H; Z 4  is selected from the group consisting of SH, SCOR 1 , SO 2 R 2 , and SO 3 H; n=0, 1, 2, 3, 4; W is selected from the group consisting of CO and SO 2 ; X 1  is selected from the group consisting of hydrogen, optionally substituted C 1-6  alkyl, and, optionally substituted C 1-6  alkoxy; X 2  is selected from the group consisting of hydrogen, optionally substituted C 1-6  alkyl, OR 3 , and the C 2-6  sugar alcohols such as ethylene glycol, glycerol, erythritol, threitol, arabitol, xylitol, ribitol, mannitol, galacitol frucitol, iditol, inositol, and sorbitol;\n Y is selected from the group consisting of N and C\u2014CN; \n R is at each occurrence independently selected from the group consisting of hydrogen, C 1-6  alkyl, C 1-6  alkenyl, C 1-6  alkynyl, halogen, C 1-6  haloalkyl, C 3-7  cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, heteroarylalkyl, alkoxyheteroarylalkyl, \n R 1a  is at each occurrence independently selected from the group consisting of hydrogen, halogen, C 1-6  alkyl, and C 1-6  alkoxy; R 1  is at each occurrence independently selected from the group consisting of hydrogen, optionally substituted C 1-6  alkyl, and optionally substituted C 1-6  alkoxy; R 2  is at each occurrence independently selected from the group consisting of hydrogen, optionally substituted C 1-6  alkyl, and optionally substituted C 1-6  alkoxy; R 3  is an optionally substituted C 1-6  alkyl; R 4  is at each occurrence independently selected from the group consisting of hydrogen, OH, and OR 5 . q=0, 1, 2, 3, 4, or 5; R 5  is at each occurrence an optionally substituted C 1-6  alkyl; two R 5  substituents can be joined together with the atoms to which they are bound to form a 5 to 6 membered ring.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 86.0
- Lexical Diversity: 1.15385
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15873293', '13354556', '12429014', '11169312', '15319637']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7713890235495792
- 35 USC 102 Novelty (BERT): 0.5519528568077228
- Combined Prediction Score: 0.7494454068753935
- Mean Citation Score: 284.493394
- Max Citation Score: 412.86075
- Similarity Product: 284.30474840775133

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test