PATENT CLAIM ANALYSIS

Application Number: 16177500
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-10
Patent Classification: ["549", "403000"]

Abstract:
Provided is a method for preparing hispidulin or a derivative thereof. The method includes selective protection of trihydroxybenzaldehyde, followed by regioselective iodination, selective protection, Stille coupling, Baeyer-Villiger oxidation and basic hydrolysis to obtain a protected intermediate compound. Then, alkylation, Claisen-Schmidt condensation, cyclization and deprotection of the protected intermediate compound are performed to obtain hispidulin or the derivative thereof. The present disclosure provides an efficient method for total synthesis of hispidulin or the derivative thereof with concise reaction steps and high yield.

Claim (Index 14):
The method of  claim 13 , wherein the palladium catalyst is Pd(PPh 3 ) 4 , PdCl 2 (PPh 3 ) 2 , Pd(dppf)Cl 2 , PdCl 2 , Pd(OAc) 2 , Pd(dba) 2 , PdCl 2 (MeCN) 2 , BnPdCl(PPh 3 ) 2 , or C 4 H 6 Br 2 N 2 Pd.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 98.0
- Lexical Diversity: 1.64286
- Patent Class: 549.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14398902', '15002692', '14123381', '13880207', '13344557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6897992475299367
- 35 USC 102 Novelty (BERT): 0.4875562668639588
- Combined Prediction Score: 0.669574949463339
- Mean Citation Score: 185.76453
- Max Citation Score: 190.09818
- Similarity Product: 143.67639873437045

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test