PATENT CLAIM ANALYSIS

Application Number: 15863498
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-07
Patent Classification: ["514", "183000"]

Abstract:
This invention describes the use of indane acetic acid derivatives which are dual PPAR delta/gamma agonists, and which penetrate the Blood Brain Barrier and achieve effective brain to plasma drug levels at non-toxic doses, for the treatment of neurodegenerative diseases including one or more of the following: Alzheimer's Disease (AD); Huntington's Disease (HD); Parkinson's Disease (PD); Amyotrophic Lateral Sclerosis (ALS); Frontal Temporal Dementia (FTD); Corticobasal Degeneration (CBD); Progressive Supranuclear Palsey (PSP); Dementia with Lewy Bodies (DLB); or Multiple Sclerosis (MS).

Claim (Index 5):
The method of treatment according to  claim 1  wherein:\n R is H, Na + , Li + , Ca + , K + , N + (C1-C6) 4 , or C1-C6 alkyl; \n R 1  is H; \n R 2  is H, halo; \n R 3  is H, C 1 -C 6  alkyl; \n X is O or S; \n R 4  is phenyl, which may be singularly or multiply substituted with R 6 ; \n R 5  is H, halo; \n R 6  is halo, CF 3 , C 1 -C 6  alkyl or C 1 -C 6  alkoxy; and \n c-1\u2032 has the S stereochemistry.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 91.0
- Lexical Diversity: 1.50667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15774638', '15830675', '15484445', '14429101', '14897396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7804395111157134
- 35 USC 102 Novelty (BERT): 0.499070911655856
- Combined Prediction Score: 0.7523026511697276
- Mean Citation Score: 249.04305400000004
- Max Citation Score: 259.62888
- Similarity Product: 204.6300642856264

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test