PATENT CLAIM ANALYSIS

Application Number: 15891492
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "012700"]

Abstract:
The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.

Claim (Index 23):
The modified relaxin polypeptide of  claim 1 , wherein said peptide component comprises Glu, Glu \u03b3 , GGGGS-Glu \u03b3  (SEQ ID NO: 139), DRDDRD (SEQ ID NO: 102), KKKKKK-Glu \u03b3  (SEQ ID NO: 103), RGGEEKKKEKEK-Glu \u03b3  (SEQ ID NO: 104), GGGEEE-Glu \u03b3  (SEQ ID NO: 105), EEEGGG-Glu \u03b3  (SEQ ID NO: 106), KKKGGG-Glu \u03b3  (SEQ ID NO: 107), GETGSSGEGT-Glu \u03b3  (SEQ ID NO: 108), GGGKKK-Glu \u03b3  (SEQ ID NO: 109), GSHHHHHGS-Glu \u03b3  (SEQ ID NO: 110), Sar-Sar-Sar-Sar-Ser-Sar-Sar-Sar-Sar-Glu \u03b3  (SEQ ID NO: 111), Sar-Sar-Sar-Sar-Ser-Glu \u03b3  (SEQ ID NO: 112), Sar-Sar-Sar-Glu-Glu-Glu \u03b3  (SEQ ID NO: 113), KKKSGGSGG-Glu \u03b3  (SEQ ID NO: 118), KKSGGSGG-Glu \u03b3  (SEQ ID NO: 114), KKSGGSGG-Glu \u03b1  (SEQ ID NO: 115), KKSAGSAG-Glu \u03b3  (SEQ ID NO: 116), KSGGSGG-Glu \u03b3  (SEQ ID NO: 117), KKSGGSGGEE-Glu \u03b3  (SEQ ID NO: 119), dKdKdKdKdKdK-Glu \u03b3  (SEQ ID NO: 120), EESGGSGG-Glu \u03b3  (SEQ ID NO: 121), GSGSGSGS-Glu \u03b3  (SEQ ID NO: 123), EEEGGG-dGly \u03b3  (SEQ ID NO: 128), EGGGGSK-Glu \u03b3  (SEQ ID NO: 130), EEEEEE-Glu \u03b3  (SEQ ID NO: 131), EEEEPEEEEPEEEEPEEEE-Glu \u03b3  (SEQ ID NO: 133), EEEEPEEEEPEEEEPEEGGG (SEQ ID NO: 135), EEEEGEEEEGEEEEGEEEE-Glu \u03b3  (SEQ ID NO: 136), KGGEEKKKEKEKEPKGGEEKKKEKEK-Glu \u03b3  (SEQ ID NO: 137), EAQKAQAEAQKAQAEAQKAQA-Glu \u03b3  (SEQ ID NO: 138), KK-Glu \u03b3  (SEQ ID NO: 140), Glu \u03b3 , KGPKGP-Glu \u03b3  (SEQ ID NO: 146), SGGGS-Glu \u03b3  (SEQ ID NO: 147), KGGGS-Glu \u03b3  (SEQ ID NO: 148), KGGGSE-Glu \u03b3  (SEQ ID NO: 149), GSPGSP-Glu \u03b3  (SEQ ID NO: 150), GGGGP-Glu \u03b3  (SEQ ID NO: 151), EGGS-Glu \u03b3  (SEQ ID NO: 152), EGGGP-Glu \u03b3  (SEQ ID NO: 153), KGPGSE-Glu \u03b3  (SEQ ID NO: 154), Spermine-Glu \u03b3 , or KKGGS-Glu \u03b3  (SEQ ID NO: 156).

Metadata:
- Claim Count in Document: 62.0
- Percentile: 88.0
- Lexical Diversity: 1.40476
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13774349', '15386347', '15239277', '13212101', '14152302']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7804146128498217
- 35 USC 102 Novelty (BERT): 0.5649952632282643
- Combined Prediction Score: 0.758872677887666
- Mean Citation Score: 442.75909400000006
- Max Citation Score: 465.6355
- Similarity Product: 316.6980869261324

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test