PATENT CLAIM ANALYSIS

Application Number: 15753353
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["544", "242000"]

Abstract:
The invention relates to a pharmaceutical composition comprising a combination of a compound of formula (I) or a pharmaceutically acceptable salt thereof, and at least one second agent selected from the group consisting of signal transduction pathway inhibitors, tumour immunotherapeutics, agents inhibiting the BCL2 family of proteins, agents inhibiting Mcl-1, proteasome Inhibitors, poly (ADP-ribose) polymerase (PARP) Inhibitors, aromatase inhibitors, conventional cytotoxic agents or a miscellaneous agent selected from abiraterone, ARN-509 and MYC inhibitors.

Claim (Index 1):
A pharmaceutical composition comprising a combination of a compound of formula (I) or a pharmaceutically acceptable salt thereof, and at least one second agent selected from the group consisting of signal transduction pathway inhibitors, tumour immunotherapeutics, agents inhibiting the BCL2 family of proteins, agents inhibiting Mcl-1, proteasome Inhibitors, poly (ADP-ribose) polymerase (PARP) Inhibitors, aromatase inhibitors, conventional cytotoxic agents or a miscellaneous agent selected from abiraterone, ARN-509 and MYC inhibitors: or a pharmaceutically acceptable salt thereof, wherein:\n W is O, N\u2014H, N\u2014(C 1 -C 10  alkyl) or S; \n each X is independently CH or N; \n R 1  is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from N or O; \n R 2  is LY; \n each L is a direct bond, C 1 -C 10  alkylene, C 2 -C 10  alkenylene or C 2 -C 10  alkynylene; \n Y is an optionally substituted fused, bridged or spirocyclic non-aromatic 5-12 membered heterocycle containing up to 4 heteroatoms selected from N or O; and \n each R 3  is independently H, C 1 -C 10  alkyl, halogen, fluoro C 1 -C 10  alkyl, O\u2014C 1 -C 10  alkyl, NH\u2014C 1 -C 10  alkyl, S\u2014C 1 -C 10  alkyl, O-fluoro C 1 -C 10  alkyl, NH-acyl, NH\u2014C(O)\u2014NH\u2014C 1 -C 10  alkyl, C(O)\u2014NH\u2014C 1 -C 10  alkyl, aryl or heteroaryl.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 88.0
- Lexical Diversity: 1.53448
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15117606', '15753358', '15753361', '15150492', '13388164']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7671003341431333
- 35 USC 102 Novelty (BERT): 0.5267693342174523
- Combined Prediction Score: 0.7430672341505653
- Mean Citation Score: 280.81890000000004
- Max Citation Score: 348.1831
- Similarity Product: 192.85633741909268

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test