PATENT CLAIM ANALYSIS

Application Number: 15896193
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["544", "395000"]

Abstract:
The present invention provides an improved process for preparation of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine; commonly known as vortioxetine (referred to as the compound (I)) and pharmaceutically acceptable salts thereof; wherein the process comprises reaction of 2-((2,4-dimethylphenyl)thio)aniline (II) with bis(2-alkyl)amine (IIIa) or its salt in the presence of a cyclic amide solvent.

Claim (Index 2):
The process according to the  claim 1 , wherein the cyclic amide solvent is selected from the group consisting of N-methyl-2-pyrrolidone (NMP), caprolactam, 2-piperidinone, azetidin-2-one, N-methyl caprolactame, 1-methylpiperidin-2-one and/or 1-methylazetidin-2-one; or a mixture thereof.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 88.0
- Lexical Diversity: 1.39286
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14945654', '14916075', '15552985', '14767350', '15304929']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.794936574940683
- 35 USC 102 Novelty (BERT): 0.4868869956363492
- Combined Prediction Score: 0.7641316170102497
- Mean Citation Score: 202.007118
- Max Citation Score: 227.7228
- Similarity Product: 169.60413443398477

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test