PATENT CLAIM ANALYSIS

Application Number: 16024145
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "250100"]

Abstract:
The present invention generally provides methods and compositions for eliciting an immune response against  Neisseria  spp. bacteria in a subject, particularly against a  Neisseria meningitidis  serogroup B strain.

Claim (Index 62):
A  Neisseria meningitidis  ( N. meningitidis ) bacteria genetically modified to disrupt production of the endogenous GNA1870 polypeptide so that the endogenous GNA1870 is not present at detectable levels in antigenic vesicles prepared from the  N. meningitidis  and to overexpress at least one full length meningococcal GNA1870 polypeptide at a level sufficient to provide for production of the isolated antigenic vesicles that, when administered to a mammalian subject, elicit anti-meningococcal GNA1870 polypeptide antibodies, wherein the overexpressed GNA1870 polypeptide is a variant 1, a variant 2, or a variant 3 GNA1870 polypeptide heterologous to the  N. meningitidis,  and wherein the antigenic vesicles are outer membrane vesicle (OMV), microvesicle (MVs), or a mixture of the OMVs and the MVs.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 94.0
- Lexical Diversity: 1.14815
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15237495', '14688594', '11795739', '13279006', '09917222']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.843423889917394
- 35 USC 102 Novelty (BERT): 0.7521989078470189
- Combined Prediction Score: 0.8343013917103566
- Mean Citation Score: 799.49578
- Max Citation Score: 888.7611
- Similarity Product: 847.3623283255579

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test