PATENT CLAIM ANALYSIS

Application Number: 15903264
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "122000"]

Abstract:
The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (−)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.

Claim (Index 9):
The non-naturally occurring polynucleotide encoding the non-naturally occurring polypeptide of  claim 6 , wherein said non-naturally occurring polypeptide sequence further comprises a combination of amino acid substitutions relative to SEQ ID NO: 136, selected from the following group consisting of:\n (a) the amino acid at position 143 is glycine; (b) the amino acid at position 143 is glycine and the amino acid at position 484 is cysteine; and (c) the amino acid at position 62 is valine, the amino acid at position 143 is glycine, the amino acid at position 275 is serine, the amino acid at position 329 is valine, and the amino acid at position 484 is cysteine.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 88.0
- Lexical Diversity: 1.85455
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15698319', '15159578', '15352970', '14952119', '15211329']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7909511429314579
- 35 USC 102 Novelty (BERT): 0.7737481875516927
- Combined Prediction Score: 0.7892308473934814
- Mean Citation Score: 726.307388
- Max Citation Score: 974.9746
- Similarity Product: 916.0283608972312

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test