PATENT CLAIM ANALYSIS

Application Number: 16058303
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "383000"]

Abstract:
The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R 1  is a 5- to 6-membered ring group which may be substituted; X 1  is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X 2  is a bivalent group of 1 to 4 atoms; Z 1  is a bivalent cyclic ring group or the like; Z 2  is a bond or the like; and R 2  is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Claim (Index 57):
A method for inhibiting binding of a ligand to a CCR5 receptor comprising administering an effective amount of a compound of Formula I, or a salt or hydrate thereof, wherein,\n Z 1a  is a 5- or 6-membered aromatic ring group; \n Z 2\u2032  is a group of \u2014Z 2a \u2014W 2 \u2014Z 2b \u2014 (wherein each of Z 2a  and Z 2b  is O, S(O)m (wherein m is 0, 1, or 2), an optionally substituted imino group, or a bond); \n W 2  is an optionally substituted alkylene chain; \n n is 1; \n Y is NR 4 , wherein R 4  is hydrogen, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group or an optionally substituted acyl group); \n R 2\u2032  is (1) an optionally substituted amino group and whose nitrogen atom is optionally converted to quarternary ammonium or oxide; (2) a nitrogen-containing heterocyclic group which is optionally substituted and may contain a sulfur atom or an oxygen atom as a ring constituent atom, and whose nitrogen atom is optionally converted to quarternary ammonium or oxide; (3) an optionally substituted amidino group; or (4) an optionally substituted guanidino group; and \n R 1  is an optionally substituted cyclic 5- to 6-membered ring.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 96.0
- Lexical Diversity: 2.59649
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14261683', '11978198', '12119355', '13476454', '10484762']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8013722879579667
- 35 USC 102 Novelty (BERT): 0.5809140593840593
- Combined Prediction Score: 0.7793264651005759
- Mean Citation Score: 479.520306
- Max Citation Score: 512.11743
- Similarity Product: 382.3626402323234

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test