PATENT CLAIM ANALYSIS

Application Number: 16291264
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-09
Patent Classification: ["435", "007210"]

Abstract:
Methods of measuring the amount of singly- or multiply-phosphorylated p217+ tau protein in a sample are provided. Methods of detecting or diagnosing tauopathies, methods of determining the effectiveness of a treatment of a tauopathy, and methods of determining whether a subject is suitable for anti-p217+ tau antibody therapy are also provided. Also described are antibodies for use in the methods and kits comprising the antibodies.

Claim (Index 19):
A kit comprising:\n a. a capture antibody directed against a p217+ tau epitope, optionally a phosphorylation-independent capture antibody directed against a tau epitope between amino acids 150 and 250 of tau protein; and b. at least one detection antibody directed against a tau protein epitope comprising amino acid residues 7 to 20 or 116 to 127 of tau protein.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 99.0
- Lexical Diversity: 1.66667
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15337964', '15750982', '16291303', '14348918', '14154954']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.596789071465039
- 35 USC 102 Novelty (BERT): 0.5317498953455131
- Combined Prediction Score: 0.5902851538530864
- Mean Citation Score: 343.305048
- Max Citation Score: 355.36682
- Similarity Product: 262.0809581980217

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test