PATENT CLAIM ANALYSIS

Application Number: 16171837
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-07
Patent Classification: ["514", "017700"]

Abstract:
Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder.

Claim (Index 77):
A pharmaceutical composition formulated for intraocular administration to an eye of a subject with an ocular condition, the composition comprising a pharmaceutically acceptable carrier, a necrosis inhibitor, and an apoptosis inhibitor,\n wherein the composition is formulated to provide a final concentration of the necrosis inhibitor in the eye in the range from about 150 \u03bcM to about 1000 \u03bcM, and wherein the composition is formulated to provide a final concentration of the apoptosis inhibitor in the range from about 150 \u03bcM to about 500 \u03bcM.

Metadata:
- Claim Count in Document: 158.0
- Percentile: 97.0
- Lexical Diversity: 1.83582
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14934810', '15288214', '15956133', '15093480', '12086792']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8416056925882295
- 35 USC 102 Novelty (BERT): 0.6669604113621908
- Combined Prediction Score: 0.8241411644656256
- Mean Citation Score: 705.1886999999997
- Max Citation Score: 903.4753
- Similarity Product: 617.7294028940678

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test