PATENT CLAIM ANALYSIS

Application Number: 16045338
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "445000"]

Abstract:
A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the composition. For progestin-only hormone therapy, the composition contains an anti-oxidant and does not contain an estrogen. For therapy involving a progestin and an estrogen, the composition contains the progestin, the estrogen and an additional anti-oxidant. Methods of improving the stability of progestin-containing compositions comprising oxidative agents are also disclosed. The methods comprise including one or more anti-oxidants in the compositions.

Claim (Index 1):
An adhesive polymer matrix composition for transdermal delivery of levonorgestrel, wherein:\n (a) the composition comprises the levonorgestrel, an anti-oxidant, and a skin permeation enhancer in a polyacrylate pressure sensitive adhesive (PSA); (b) the composition comprises at least one component that contributes to oxidative degradation of the levonorgestrel, wherein the at least one component is one or more of (i) the polyacrylate PSA, (ii) the skin permeation enhancer wherein the enhancer comprises dimethyl sulfoxide (DMSO), and (iii) polyvinyl pyrrolidone (PVP) or a PVP copolymer; (c) (i) the anti-oxidant is not an estrogen; (ii) the anti-oxidant is not a sulfoxide or a fatty acid; and (iii) the anti-oxidant protects against oxidative degradation of the levonorgestrel by the one or more of the PSA, the DMSO and the PVP or PVP copolymer; and (d) the stability of the composition is improved over the stability of such composition lacking the anti-oxidant.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 95.0
- Lexical Diversity: 1.91667
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13667632', '10621711', '12543859', '12556740', '10130913']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.769382773141013
- 35 USC 102 Novelty (BERT): 0.636485614592097
- Combined Prediction Score: 0.7560930572861214
- Mean Citation Score: 383.00605
- Max Citation Score: 630.05255
- Similarity Product: 550.7947847861586

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test