PATENT CLAIM ANALYSIS

Application Number: 16058437
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-01
Patent Classification: ["424", "049000"]

Abstract:
Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I): wherein: L represents a linker selected from —C≡C—, (a tolan), —CH═CH— (a stilbene, preferably trans); or —CR a ═CR b — a stilbene derivative; where R a  and R b  are independently H or phenyl optionally substituted with —(R 3 ) p  or —(R 4 ) q ; R 1  to R 4  are independent substituents at any available position of the phenyl rings, preferably at 3, 3′, 4, 4′, and/or 5, 5′; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ≥1. Each R 1  to R 2  is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.

Claim (Index 7):
The method of  claim 4 , wherein the auxiliary autophagy modulating compound is selected from the group consisting of: substituted or unsubstituted parabenzoquinone, substituted or unsubstituted orthobenzoquinone, substituted or unsubstituted anthraquinone, an amino acid, an acidic monosaccharide, and a vitamin or a salt thereof.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 96.0
- Lexical Diversity: 2.10619
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15093146', '11665807', '15106283', '13990301', '15106284']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7626367032724125
- 35 USC 102 Novelty (BERT): 0.5933735347770164
- Combined Prediction Score: 0.7457103864228729
- Mean Citation Score: 258.67112000000003
- Max Citation Score: 616.81635
- Similarity Product: 409.2780228659481

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test