PATENT CLAIM ANALYSIS

Application Number: 16185271
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["514", "293000"]

Abstract:
Methods for treating a subject having a cancerous tumor are disclosed. The methods comprise administering to the subject an effective amount of a non-steroidal selective glucocorticoid receptor modulator (SGRM) and an effective amount of a chemotherapeutic agent. The tumor may be cervical cancer. The SGRM may be a fused azadecalin. In embodiments, the SGRM may be a heteroaryl ketone fused azadecalin or an octahydro fused azadecalin.

Claim (Index 7):
A method of treating a subject hosting a cervical cancer tumor, the method comprising administering to the subject an effective amount of a chemotherapeutic agent and orally administering an effective amount of non-steroidal selective glucocorticoid receptor modulator (SGRM) to reduce the tumor load of the cervical cancer tumor wherein the SGRM is a fused azadecalin compound having the following formula: wherein\n L 1  and L 2  are members independently selected from a bond and unsubstituted alkylene; \n R 1  is a member selected from unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted heterocycloalkyl, \u2014OR 1A , NR 1C R 1D , \u2014C(O)NR 1C R 1D , and \u2014C(O)OR 1A , wherein \n R 1A  is a member selected from hydrogen, unsubstituted alkyl and unsubstituted heteroalkyl, \n R 1C  and R 1D  are members independently selected from unsubstituted alkyl and unsubstituted heteroalkyl, \n wherein R 1C  and R 1D  are optionally joined to form an unsubstituted ring with the nitrogen to which they are attached, wherein said ring optionally comprises an additional ring nitrogen; \n R 2  has the formula: \n wherein R 2G  is a member selected from hydrogen, halogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, \u2014CN, and \u2014CF 3 ; J is phenyl; t is an integer from 0 to 5; X is \u2014S(O 2 )\u2014; and R 5  is phenyl optionally substituted with 1-5 R 5A  groups, wherein R 5A  is a member selected from hydrogen, halogen, \u2014OR 5A1 , S(O 2 )NR 5A2 R 5A3 , \u2014CN, and unsubstituted alkyl, wherein R 5A1  is a member selected from hydrogen and unsubstituted alkyl, and R 5A2  and R 5A3  are members independently selected from hydrogen and unsubstituted alkyl, or salts and isomers thereof.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 98.0
- Lexical Diversity: 1.64444
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15942312', '15915477', '16150916', '15697878', '15987365']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7953105535513059
- 35 USC 102 Novelty (BERT): 0.6263888168449613
- Combined Prediction Score: 0.7784183798806714
- Mean Citation Score: 499.5320019999999
- Max Citation Score: 564.31116
- Similarity Product: 540.5399971817278

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test