PATENT CLAIM ANALYSIS

Application Number: 15946402
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["424", "085200"]

Abstract:
The present invention relates to a therapeutic polypeptide and methods for its creation and use for modulating an immune response in a host organism in need thereof. In particular, the invention relates to the administration to an organism in need thereof, of an effective amount of a pre-coupled polypeptide complex comprising a lymphokine polypeptide portion, for example IL-15 (SEQ ID NO: 5, 6), IL-2 (SEQ ID NO: 10, 12) or combinations of both, and an interleukin receptor polypeptide portion, for example IL-15Ra (SEQ ID NO: 7, 8), IL-2Ra (SEQ ID NO: 9, 11) or combinations of both, for augmenting the immune system in, for example, cancer, SCID, AIDS, or vaccination; or inhibiting the immune system in, for example, rheumatoid arthritis, or Lupus. The therapeutic complex of the invention surprisingly demonstrates increased half-life, and efficacy in vivo.

Claim (Index 13):
A method of increasing the activity of an immune cell comprising treating an immune ell with an effective amount of the polypeptide complex of  claim 12 .

Metadata:
- Claim Count in Document: 9.0
- Percentile: 91.0
- Lexical Diversity: 2.21795
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15158210', '11435497', '15156618', '13368605', '14567382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8368635429188234
- 35 USC 102 Novelty (BERT): 0.5882041176395103
- Combined Prediction Score: 0.8119976003908921
- Mean Citation Score: 632.3829900000002
- Max Citation Score: 638.5672
- Similarity Product: 411.7726469009877

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test