PATENT CLAIM ANALYSIS

Application Number: 15974429
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["435", "053000"]

Abstract:
The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.

Claim (Index 23):
The method of  claim 14 , wherein the mogroside compound glycosylated at C3\u2032-OH, the mogroside compound glycosylated at C24\u2032-OH, the mogroside compound glycosylated at C3\u2032-OH and C24\u2032-OH, the mogroside compound di-glycosylated at C24\u2032 position, the mogroside compound tri-glycosylated at C24\u2032 position, the mogroside compound glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position and oxidized at C11-OH, the mogroside compound di-glycosylated at C3\u2032-OH and di-glycosylated at C24\u2032 position, an isomer thereof, and/or the mogroside composition thereof is produced in a cell culture broth, the method comprising growing a recombinant host cell comprising one or more genes encoding one or more polypeptides capable of glycosylation at C3\u2032-OH, C24\u2032-OH, C3\u2032-OH and C24\u2032-OH of the mogrol, at C3\u2032-OH or C24\u2032-OH of the glycosylated mogroside compound, or both C3\u2032-OH, C24\u2032-OH, C3\u2032-OH and C24\u2032-OH of the mogrol and C3\u2032-OH or C24\u2032-OH of the glycosylated mogroside compound or beta-1,6-glycosylation of the C2\u2032 position of the 24-O-glucose, and/or beta-1,2-glycosylation of the C6\u2032 position of the 3-O-glucose and/or the 24-O-glucose of the glycosylated mogroside compound;\n wherein at least one of the genes is a recombinant gene, under conditions in which one or more of the genes are expressed; \n wherein contacting the mogroside compound glycosylated at C3\u2032-OH, the mogroside compound glycosylated at C24\u2032-OH, the mogroside compound glycosylated at C3\u2032-OH and C24\u2032-OH, the mogroside compound di-glycosylated at C24\u2032 position, the mogroside compound tri-glycosylated at C24\u2032 position, the mogroside compound glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position and oxidized at C11-OH, the mogroside compound di-glycosylated at C3\u2032-OH and di-glycosylated at C24\u2032 position, an isomer thereof, and/or the mogroside composition thereof with the polypeptide comprises contacting the mogroside compound glycosylated at C3\u2032-OH, the mogroside compound glycosylated at C24\u2032-OH, the mogroside compound glycosylated at C3\u2032-OH and C24\u2032-OH, the mogroside compound di-glycosylated at C24\u2032 position, the mogroside compound tri-glycosylated at C24\u2032 position, the mogroside compound glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position, the mogroside compound di-glycosylated at C3\u2032-OH and tri-glycosylated at C24\u2032 position and oxidized at C11-OH, the mogroside compound di-glycosylated at C3\u2032-OH and di-glycosylated at C24\u2032 position, an isomer thereof, and/or the mogroside composition thereof with at least one of the polypeptides produced by the recombinant host cell; \n wherein the recombinant host cell is a microorganism that is a plant cell, a mammalian cell, an insect cell, a fungal cell, an algal cell, or a bacterial cell.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 93.0
- Lexical Diversity: 1.54545
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15900557', '14504109', '14442694', '15511565', '15519326']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7292925494805735
- 35 USC 102 Novelty (BERT): 0.7109632005785056
- Combined Prediction Score: 0.7274596145903668
- Mean Citation Score: 758.4892920000003
- Max Citation Score: 915.48206
- Similarity Product: 740.7183100500513

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test