PATENT CLAIM ANALYSIS

Application Number: 16046476
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "489000"]

Abstract:
A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution, an organic solvent, an oil, or a cyclodextrin, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.

Claim (Index 23):
A directly infusible nimodipine formulation suitable for parenteral administration in humans, comprising nimodipine in a concentration from about 0.01 mg/ml to about 1.0 mg/ml, a pharmaceutically acceptable organic solvent comprising less than 2% w/v of the formulation, a pharmaceutically acceptable aqueous carrier, and an effective amount of a hydrophilic surfactant such that the nimodipine is substantially contained in micelles, the formulation comprising a volume from about 50 ml to about 1000 ml and contained in a pharmaceutically acceptable container, the formulation being a stable clear micellar solution and displaying no precipitation of nimodipine.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 95.0
- Lexical Diversity: 1.69643
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15485813', '15638901', '15094461', '15754429', '13452033']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7482750807070444
- 35 USC 102 Novelty (BERT): 0.6474562820753534
- Combined Prediction Score: 0.7381932008438754
- Mean Citation Score: 402.348346
- Max Citation Score: 621.5713
- Similarity Product: 600.6982286109567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test