PATENT CLAIM ANALYSIS

Application Number: 16044752
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["544", "106000"]

Abstract:
The present invention relates to compounds that act as pan-Rac inhibitors, compositions including the compounds, and methods of using the compounds. In particular, the compounds are useful for treating certain cancers such as breast cancer.

Claim (Index 3):
A compound of  claim 1  or a pharmaceutically acceptable salt thereof, wherein\n Z is selected from Cl, F, CH 3 , and CF 3 ; \n R 1 , R 2 , and R 3  are independently selected from H and F; \n A is selected from \u2014(CH 2 ) m \u2014, \u2014(CH 2 ) 3 \u2014O\u2014(CH 2 ) 3 \u2014, \u2014(CH 2 ) 3 \u2014O\u2014(CH 2 ) 2 \u2014, \u2014O\u2014(CH 2 ) 5 \u2014, \u2014(CH 2 ) 5 \u2014O\u2014, \u2014(CH 2 ) 3 \u2014N(CH 3 )\u2014(CH 2 ) 2 \u2014, \u2014(CH 2 ) 5 \u2014C(O)\u2014, and \n Linker is selected from a bond, \u2014C(O)\u2014, \u2014CH 2 \u2014, \u2014(CH 2 ) 2 \u2014, \u2014CH(CH 3 )\u2014, \u2014CH(OH)\u2014, \u2014CH 2 \u2014NH\u2014, \u2014CH 2 \u2014N(CH 3 )\u2014, \u2014CH 2 \u2014N(CH 3 )\u2014C(O)\u2014, and \u2014CH 2 \u2014NH\u2014C(O)\u2014; D is selected from: (i) a 4-7 membered ring optionally containing 1 or 2 heteroatoms independently selected from N and O; wherein said ring optionally contains a C\u2550O; and wherein said ring is optionally substituted with one or more groups selected from CH 3 , F, OH, CF 3 , O\u2014CH 3 , C(O)\u2014R e , phenyl, 4-methoxyphenyl, and piperazine; (ii) \u2014N(R f )(R g ); and (iii) \u2014C(O)\u2014O\u2014C(CH 3 ) 3 ; R e  is selected from CH 3 , CH(CH 3 ) 2 , and tetrahydropyran; R f  is selected from H, CH 3 , CH 2 \u2014CH 3 , C(O)\u2014CH 3 , and C(O)\u2014O\u2014C(CH 3 ) 3 ; R g  is selected from CH 2 \u2014CH 2 \u2014O\u2014CH 3 , CH(CH 3 )\u2014CH 2 \u2014O\u2014CH 3 , C(CH 3 ) 2 \u2014CH 2 \u2014O\u2014CH 3 , CH 2 \u2014C(CH 3 ) 2 \u2014O\u2014CH 3 , and CH 2 \u2014CH 3 ; and m is selected from 3, 4, 5, 6, and 7.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 95.0
- Lexical Diversity: 1.29032
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10894940', '15266411', '12394072', '15499443', '13822809']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8296530561870813
- 35 USC 102 Novelty (BERT): 0.5313657668426836
- Combined Prediction Score: 0.7998243272526415
- Mean Citation Score: 354.313954
- Max Citation Score: 371.0986
- Similarity Product: 273.2724555283546

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test