PATENT CLAIM ANALYSIS

Application Number: 15949802
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "009100"]

Abstract:
Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided.

Claim (Index 32):
The method of  claim 31 , wherein the composition is administered locally at or near an occluded blood vessel.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 91.0
- Lexical Diversity: 1.87952
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12783005', '13669856', '15295833', '15295804', '14593107']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8980488665762285
- 35 USC 102 Novelty (BERT): 0.6434899772977907
- Combined Prediction Score: 0.8725929776483847
- Mean Citation Score: 760.030852
- Max Citation Score: 803.26776
- Similarity Product: 563.8753125283813

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test