PATENT CLAIM ANALYSIS

Application Number: 15916595
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "497000"]

Abstract:
The present invention relates to generally to pharmaceutical formulations. Particularly, the present invention relates to a drug nanocarrier that is stabilized by lipids, preferably lecithins and/or lipid-terminated polyalkylene glycol, for the delivery of poorly soluble drugs with high drug loading and its utility in the fields of pharmaceutical formulation, drug delivery, medicine and diagnosis.

Claim (Index 1):
A method of preparing a nanocarrier with higher bioactive or diagnostic agent loading, comprising (i) preparing a nanosuspension comprising one or more amphiphilic lipids by subjecting the one or more amphiphilic lipids to ultrasonication; (iia) preparing a thin film comprising a mixture of one or more amphiphilic polymers wherein the mixture optionally comprises an emulsifier and an active agent or a diagnostic agent by dissolving the mixture in an organic solvent and then removing the organic solvent or (iib) dissolving the mixture in an organic solvent to form an organic solution; (iii) hydrating the thin film of (iia) with the nanosuspension or injecting the organic solution of (iib) into the nanosuspension to form a solution containing self-assembling micelles encapsulating the active agent or diagnostic agent; and (iv) subjecting the micellar solution to ultrasonication at a temperature of lower than 50\u00b0 C. until the amphiphilic lipid forms a lipid shell and then encloses micelles as a core.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 90.0
- Lexical Diversity: 1.4186
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14765620', '15060663', '15798287', '12573591', '14490336']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6638822333893772
- 35 USC 102 Novelty (BERT): 0.5008408924287086
- Combined Prediction Score: 0.6475780992933104
- Mean Citation Score: 228.744078
- Max Citation Score: 239.43407
- Similarity Product: 162.75951092007696

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test