PATENT CLAIM ANALYSIS

Application Number: 15903379
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["514", "021300"]

Abstract:
The present invention provides a peptide at least partially derivable from human Thyroid Stimulating Hormone Receptor (TSHR) which peptide is capable of binding to an MHC molecule in vitro and being presented to a T cell without further antigen processing. The present invention also relates to the use of such peptides for the prevention or suppression of activating autoantibody formation in Graves' Disease.

Claim (Index 3):
A peptide which comprises the sequence:\n KK-(G/K)-aa1-(RNB-5D peptide)-aa2-aa3-Z-(G/K)-KK wherein aa1 is no amino acid, I, K or T; RNB-5D peptide is YVSIDVTLQQLE, or a variant thereof in which one or more amino acids has been replaced by K; aa2 is no amino acid, S or K; aa3 is no amino acid, H or K; which is capable of binding to an MHC molecule in vitro and being presented to a T cell without antigen processing.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 88.0
- Lexical Diversity: 1.21429
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14910372', '15537577', '13320201', '13706540', '11979224']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7848771105179373
- 35 USC 102 Novelty (BERT): 0.6250411065267423
- Combined Prediction Score: 0.7688935101188178
- Mean Citation Score: 359.11758
- Max Citation Score: 627.2011
- Similarity Product: 508.39174245944025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test