PATENT CLAIM ANALYSIS

Application Number: 15912295
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "020800"]

Abstract:
The invention provides a protein composition derived from silk fibroin, which composition possesses enhanced solubility and stability in aqueous solutions. The primary amino acid sequence of native fibroin is modified in the SDP such that cysteine disulfide bonds between the fibroin heavy and fibroin light protein chains are reduced or eliminated. Additionally, the composition can have a serine content that is reduced by greater than 40% compared to native fibroin protein, and the average molecular weight of the SDP is less than about 100 kDa.

Claim (Index 16):
The fibroin-derived protein composition of  claim 1  wherein the primary amino acid sequences of the fibroin-derived protein composition differ from native fibroin by at least by at least 6% with respect to the combined difference in serine, glycine, and alanine content; the average molecular weight of the fibroin-derived protein is less than about 100 kDa and greater than about 30 kDa; and the fibroin-derived protein composition maintains an optical absorbance at 550 nm of less than 0.25 for at least two hours after five seconds of ultrasonication.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 1.46032
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14831473', '15212086', '14877907', '14876799', '14877904']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7903500568958762
- 35 USC 102 Novelty (BERT): 0.6334632573480641
- Combined Prediction Score: 0.7746613769410949
- Mean Citation Score: 436.771778
- Max Citation Score: 674.20886
- Similarity Product: 508.0386287550902

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test