PATENT CLAIM ANALYSIS

Application Number: 15941063
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["544", "281000"]

Abstract:
Certain pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds that inhibit cycline dependent kinase (CDK) (e.g., CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, CDK10, CDK11, CDK12, CDK13, etc.) are disclosed. Pharmaceutical compositions comprising these compounds, and the use of these compounds and compositions to inhibit CDK; to treat disorders associated with CDK such as those arising from an inappropriate activity, mutation, overexpression, or upstream pathway activation of CDK; or disorders that are ameliorated by the inhibition of CDK; proliferative disorders; cancer; viral infections; neurodegenerative disorders; ischaemia; renal diseases; and cardiovascular disorders are also disclosed. Optionally, the treatment further comprises simultaneous or sequential treatment with a further active agent, e.g., an aromatase inhibitor, an anti-estrogen, a Her2 blocker, a cytotoxic chemotherapeutic agent, etc.

Claim (Index 136):
A method according to  claim 123 , wherein:\n \u2014R 7  is \u2014R 7X ; \u2014R 7X  is -L 7 -R 7D ; -L 7 - is \u2014CH 2 \u2014; \u2014R 7D  is phenyl, and is optionally substituted with one or more substituents \u2014W 3 ; each \u2014W 3  is independently: \u2014F, \u2014Cl, \u2014Br, \u2014I, \u2014CF 3 , \u2014OH, \u2014OR W3 , \u2014OCF 3 , or \u2014CN; and each \u2014R W3  is independently linear or branched saturated C 1-4 alkyl.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 1.8
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15117982', '12631373', '13773052', '12843494', '13060154']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7505406942934177
- 35 USC 102 Novelty (BERT): 0.6845516866567534
- Combined Prediction Score: 0.7439417935297513
- Mean Citation Score: 400.453204
- Max Citation Score: 741.6448
- Similarity Product: 658.5522109725952

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test