PATENT CLAIM ANALYSIS

Application Number: 15950365
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "093700"]

Abstract:
A biological composition has a mixture of mechanically selected allogeneic biologic material derived from placental tissue. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

Claim (Index 15):
A method of making a biological composition comprises the steps of:\n collecting, recovering and processing placental tissue from a donor; mechanically separating cellular and non-cellular components of bone marrow from cadaverous bone; concentrating by centrifugation and filtering; separation by density gradient centrifugation; collecting non-cellular fractions or non-cellular components or combinations thereof of predetermined density; washing the non-cellular fractions or non-cellular components or combinations thereof to create a mixture; quantifying non-whole cell fraction concentration exceeds zero; suspending to a predetermined concentration in a polyampholyte cryoprotectant; freezing the mixture at a predetermined controlled rate; and packaging a blend with lot specific allograft placental tissue having particles in the size range of 100 to 300 \u03bcm of demineralized cortical bone, mineralized cortical bone and mineralized cancellous bone either within the mixture or separate.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 91.0
- Lexical Diversity: 1.68085
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14682523', '15080818', '14683221', '15591513', '15400392']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7424140113510931
- 35 USC 102 Novelty (BERT): 0.4885698490311838
- Combined Prediction Score: 0.7170295951191022
- Mean Citation Score: 219.212178
- Max Citation Score: 249.7922
- Similarity Product: 214.68673082170488

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test