PATENT CLAIM ANALYSIS

Application Number: 15861152
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["544", "315000"]

Abstract:
Described are deuterium-substituted tetrahydrocarbazole compounds of Formulae I, II, or III which are inhibitors of sirtuin 1 (SIRT1). Also described are pharmaceutical compositions comprising the deuterium-substituted tetrahydrocarbazole compounds, and methods of use thereof.

Claim (Index 1):
A method of treating a SIRT1-mediated disorder comprising administering a therapeutically effective amount of a compound of Formula III to a patient in need thereof, wherein the compound of Formula III is: or a salt, prodrug, or solvate thereof, wherein:\n R 1 -R 7  are, independently, hydrogen or deuterium; \n at least one of R 1 -R 7  is deuterium; and \n at least one of R 1 -R 7  has deuterium enrichment of no less than about 10%.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 1.33333
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14718993', '12616242', '15071797', '14297249', '14107953']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.733600941366831
- 35 USC 102 Novelty (BERT): 0.4688058177873895
- Combined Prediction Score: 0.7071214290088869
- Mean Citation Score: 169.692396
- Max Citation Score: 175.61078
- Similarity Product: 134.24925342172858

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test