PATENT CLAIM ANALYSIS

Application Number: 15779929
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["548", "435000"]

Abstract:
The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Claim (Index 10):
The norbornenone compound of  claim 1 , wherein the compound of Formula 1 is selected from a compound of Formula 1a or Formula 1b, or a pharmaceutically acceptable salt thereof: wherein R 1 , R 2 , R 3 , R 4 , and X, are as defined according to any one of  claims 1  to  9 ; each A1 is independently selected from C\u2550O, C\u2550S, C\u2550CR 12 R 13 , S\u2550O, S(\u2550O) 2 , S, NR 14 ; each A 2 , A 3  and A 4 , are independently selected from CR 14 R 15 , CR 14 , C\u2550O, C\u2550S, C\u2550CR 12 R 13 , S\u2550O, S(\u2550O) 2 , O, S, SN, NR 14 ; and the dotted lines denote optional double bonds; R 12  and R 13  are each independently selected from hydrogen, C 1-10 alkyl, and C 1-10 haloalkyl; R 14  and R 15  are each independently selected from hydrogen, halo, CN, NO 2 , OC(O)R 5 , C(O)R 5 , C(O)OR 5 , OR 5 , OS(O) 2 R 5 , NR 5 R 6 , SR 5 , C 1-20 alkyl, C 2-20 alkenyl, C 2-20 alkynyl, monocyclic and polycyclic carbocyclyl or heterocyclyl, polyethylene glycol, amino acid, and mono- or poly-saccharide; wherein the C 1-20 alkyl, C 2-20 alkenyl, C 2-20 alkynyl, are each optionally interrupted with one or more heteroatoms selected from O, N and S; and wherein the C 1-20 alkyl, C 2-20 alkenyl, C 2-20 alkynyl, carbocycle, and heterocycle, are each optionally substituted with one or more substituents independently selected from halo, CN, NO 2 , OC(O)R 5 , C\u2550O, C(O)R 5 , C(O)OR 5 , OR 5 , OS(O) 2 R 5 , NR 5 R 6 , SR 5 , monocyclic and polycyclic heterocyclyl, polyethylene glycol, amino acid, and mono- or poly-saccharide; and R 5  and R 6  are each independently selected from hydrogen, C 1-10 alkyl, and C 1-10 haloalkyl.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 1.225
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11311731', '11338587', '12643641', '10561153', '11785998']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7721021556344323
- 35 USC 102 Novelty (BERT): 0.5291253164438581
- Combined Prediction Score: 0.7478044717153749
- Mean Citation Score: 294.66267
- Max Citation Score: 354.02344
- Similarity Product: 229.3432524278545

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test