PATENT CLAIM ANALYSIS

Application Number: 16158295
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["435", "440000"]

Abstract:
Disclosed and claimed are mutation(s) or modification(s) of the CRISPR enzyme, for example a Cas enzyme such as a Cas9, which obtain an improvement, for instance a reduction, as to off-target effects of a CRISPR-Cas or CRISPR-enzyme or CRISPR-Cas9 system or complex containing or including such a mutated or modified Cas or CRISPR enzyme or Cas9. Methods for making and using and uses of such mutated or modified Cas or CRISPR enzyme or Cas9 and systems or complexes containing the same and products from such methods and uses are also disclosed and claimed.

Claim (Index 25):
A method for treating a disease or disorder selected from the group consisting of a blood or coagulation disease or disorder, a cell dysregulation or oncology disease or disorder, an inflammation or immune related disease or disorder, a metabolic, liver, kidney or protein disease or disorder, a muscular or skeletal disease or disorder, a neurological or neuronal disease or disorder, or an ocular disease or disorder, comprising delivering to a subject in need thereof the CRISPR-Cas complex of  claim 13 .

Metadata:
- Claim Count in Document: 29.0
- Percentile: 97.0
- Lexical Diversity: 1.98113
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15179353', '14222930', '14293498', '14971356', '14523799']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6362745463835567
- 35 USC 102 Novelty (BERT): 0.5374214372245056
- Combined Prediction Score: 0.6263892354676517
- Mean Citation Score: 466.695302
- Max Citation Score: 470.5256
- Similarity Product: 275.92290174894333

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test