PATENT CLAIM ANALYSIS

Application Number: 15752308
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "009420"]

Abstract:
Nanoparticles and nanoprobes for use as a contrast agent for X-ray imaging techniques, CT scanning techniques, MRI and optical imaging are disclosed. The nanoparticles and nanoprobes include a core having a contrast element characterized by a K-edge value ranging from about 17 to about 49 keV, and a stabilizing element which minimizes one or both of cytotoxicity and immunoreactivity of the contrast element. A first coating layer encapsulates the core, the first coating layer configured to render the nanoparticles soluble in a biological medium. A method for dual energy x-ray imaging includes the steps of administering to a subject the nanoparticles disclosed herein as a contrast agent; acquiring an image with a low energy spectrum; and acquiring an image with a high energy spectrum.

Claim (Index 6):
The nanoparticles of  claim 5 , wherein the one or more biodegradable carrier matrices are selected from the group consisting of spermine and polyphosphazene.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 88.0
- Lexical Diversity: 1.78667
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12843664', '12675633', '13729815', '13580594', '15390106']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7456677739082411
- 35 USC 102 Novelty (BERT): 0.489335953627308
- Combined Prediction Score: 0.7200345918801478
- Mean Citation Score: 166.35510599999995
- Max Citation Score: 168.94603999999995
- Similarity Product: 107.9149806974315

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test