PATENT CLAIM ANALYSIS

Application Number: 15745829
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "04400A"]

Abstract:
Process for inducing resistance to diphtheria toxin in a human cell, wherein the process is carried out in vitro and/or in vivo in a rodent xenografted with a human cell, the process comprising: a) providing at least one expression vector containing at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript of the human cell; c) transducing the at least one vector into the human cell; d) allowing transcription in the human cell, from the at least one expression vector, of the at least one nucleotide sequence targeting by RNA interference the DPH2 gene transcript; e) obtaining silencing of the DPH2 gene in the human cell, whereby the human cell is resistant to diphtheria toxin.

Claim (Index 9):
Isolated transgenic diphtheria toxin resistant human cell, comprising at least one expression vector containing at least one nucleotide sequence targeting by RNA interference the human DPH2 gene transcript, wherein transcription of the at least one expression vector silences the DPH2 gene in the human cell.

Metadata:
- Claim Count in Document: 52.0
- Percentile: 86.0
- Lexical Diversity: 2.27586
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13942394', '13982530', '12305008', '11680414', '14164625']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.661511851609674
- 35 USC 102 Novelty (BERT): 0.5040083293063482
- Combined Prediction Score: 0.6457614993793414
- Mean Citation Score: 238.54697
- Max Citation Score: 244.50845
- Similarity Product: 182.71908766805828

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test