PATENT CLAIM ANALYSIS

Application Number: 15949389
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["544", "182000"]

Abstract:
The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TRβ mutation.

Claim (Index 15):
The method of  claim 12 , wherein the morphic form has a purity of Compound A of 95% or greater.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 91.0
- Lexical Diversity: 1.61017
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15046213', '14660720', '15291948', '14808388', '15373874']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7500551781469763
- 35 USC 102 Novelty (BERT): 0.6170557368236078
- Combined Prediction Score: 0.7367552340146394
- Mean Citation Score: 326.111726
- Max Citation Score: 544.6785
- Similarity Product: 513.9267835021019

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test