PATENT CLAIM ANALYSIS

Application Number: 16091699
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-09
Patent Classification: ["514", "456000"]

Abstract:
A method for providing isoflavonoid compounds to the central nervous system comprising the step of rectally administering the compound to an individual in need thereof. This method is useful in the treatment of brain cancers, including glioblastoma multiforme.

Claim (Index 1):
A method for providing a compound of general formula (I) wherein R 1  is H, C 1-10  alkyl, aryl, arylalkyl or R A CO where R A  is C 1-10  alkyl or an amino acid; R 2  is H, OH or OR 6 ; R 3  is H, OH, or R B  where R B  is an amino acid or COR A  where R A  is as previously defined; A and B together with the atoms between them form a six membered ring selected from the group or A is \u2014OR 6  and B is: wherein R 4  is H, COR D  where R D  is H, OH, C 1-10  alkyl or an amino acid, CO 2 R C  where R C  is C 1-10  alkyl, COR E  where R E  is H, C 1-10  alkyl or an amino acid, COOH, COR C  where R C  is as previously defined, or CONHR E  where R E  is as previously defined; R 5  is H, CO 2 R C  where R C  is as previously defined, or COR C OR E  where R C  and R E  are as previously defined, and where the two R 5  groups are attached to the same group they are the same or different; R 6  is C 1-10  alkyl, aryl or arylalkyl; X is O, N or S; Y is where R 7A  and R 7B  are each independently H, OH or OR 7 ; with the proviso that at least one of R 7A  and R 7B  is OH or OR 7 ; wherein R 7  is C 1-10  alkyl, aryl or arylalkyl; and \u201c \u201d represents either a single bond or a double bond; to the central nervous system (CNS), especially to brain tissue, of an individual including the step of rectally administering the compound of general formula (I) to an individual requiring provision of the compound to the CNS, thereby providing the compound to the CNS of the individual.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 97.0
- Lexical Diversity: 1.24242
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15714647', '11909538', '15968462', '13907427', '11303854']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7559524649744204
- 35 USC 102 Novelty (BERT): 0.4912287317792995
- Combined Prediction Score: 0.7294800916549083
- Mean Citation Score: 174.40313799999996
- Max Citation Score: 178.48242
- Similarity Product: 118.49377967082025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test