PATENT CLAIM ANALYSIS

Application Number: 15975654
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "480000"]

Abstract:
Provided herein are compounds, compositions and methods for the treatment of diseases and disorders associated with the liver X receptor, including bis-octahydrophenanthrene carboxamides and protein (e.g., antibody) drug conjugates thereof.

Claim (Index 2):
The compound of  claim 1  according to Formula I: or a pharmaceutically acceptable salt, solvate, or stereoisomeric form thereof, wherein\n each of Q 1  and Q 2  is independently \u2014CH 2 \u2014, \u2014C(O)\u2014, \u2014C(H)(OH)\u2014, or \u2014C(OH) 2 \u2014; \n W is \u2014CH 2 \u2014, \u2014N(H)\u2014, or \u2014O\u2014; \n R 1  is independently \u2014H, \u2014OH, \u2014NH 2 , alkyl, or \u2014OP(O)(OR 6 ) 2 ; \n R 2  is independently \u2014H, \u2014OH, \u2014CH 2 NH 2 , R 3 , R 4 , R 5 , or \u2014O\u2014R 5 ; \n wherein R 1  and R 2  are not simultaneously \u2014H; \n R 3  is \u2014N(R 6 ) 2 ; \n R 4  is \u2014X\u2014Y\u2014Z; \n X is selected from the group consisting of \u2014O\u2014 and \u2014N(H)\u2014; \n Y is selected from the group consisting of alkylene, substituted alkylene (will include oxo, i.e. \u2550O substitution), heteroalkylene, and substituted heteroalkylene; \n Z is selected from the group consisting of \u2014OH and \u2014NH 2 ; \n R 5  is alkyl, heterocycloalkyl, or substituted heterocycloalkyl, wherein each heterocycloalkyl or substituted heterocycloalkyl comprises one, two, or three heteroatoms selected from nitrogen and oxygen, and includes at least one \u2014OH and \u2014CH 2 OH, or at least one primary or secondary nitrogen; \n each R 6  is, independently in each instance, \u2014H, an amino acid residue, an N-alkyl amino acid residue, a peptide, or alkyl; and \n each R 7  is independently halo, C 1-6  alkyl, C 1-6  alkoxy, \u2014CN, O-glucose, O-amino acid residue, and O-PEG n , wherein each n is an integer from 0-3.

Metadata:
- Claim Count in Document: 25.0
- Percentile: 93.0
- Lexical Diversity: 1.16129
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14253881', '14430230', '15581749', '14843520', '15048865']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8133020478978461
- 35 USC 102 Novelty (BERT): 0.5100260220484526
- Combined Prediction Score: 0.7829744453129068
- Mean Citation Score: 281.39966200000003
- Max Citation Score: 288.1575
- Similarity Product: 207.0903940272332

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test