PATENT CLAIM ANALYSIS

Application Number: 15969864
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["544", "281000"]

Abstract:
The invention is fused heterocyclic compounds of formula (I), and salts thereof, compositions thereof, and methods of use therefor. In particular, disclosed herein are certain fused heterocyclic compounds that can be useful for inhibiting protein kinase, including Bruton's tyrosine kinase (Btk), and for treating disorders mediated thereby.

Claim (Index 3):
The compound of  claim 1 , wherein:\n (i) S/D is a double bond and R 5  and R 7  are absent; R 1  is H, halogen, alkoxy,heteroalkyl, alkyl, alkenyl, cycloalkyl, aryl, saturated or unsaturated heterocyclyl, heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heteroaryl, aryl, and saturated or unsaturated heterocyclyl are optionally substituted with at least one substituent R 16 ; and R 16  is halogen, lower alkyl, or lower alkoxy; or (ii) S/D is a double bond and R 5  and R 7  are absent; p is 1 and m is 0, 1 or 2; or (iii) S/D is a double bond and R 5  and R 7  are absent; p is 1 and m is 0, 1 or 2; A is phenyl; and each R 2  is independently halogen, lower alkyl, or lower alkoxy; or (iv) S/D is a double bond and R 5  and R 7  are absent; and R 4  and R 6 , together with the atoms to which they are attached, form a ring selected from cycloalkyl, saturated or unsaturated heterocycle, aryl, and heteroaryl rings optionally substituted with at least one substituent R 16 ; or (v) S/D is a double bond and R 5  and R 7  are absent; R 4  and R 6 , together with the atoms to which they are attached, form a ring selected from cycloalkyl, saturated or unsaturated heterocycle, aryl, and heteroaryl rings optionally substituted with at least one substituent R 16 ; A is phenyl; and each R 2  is independently halogen, lower alkyl, or lower alkoxy; or (vi) S/D is a double bond and R 5  and R 7  are absent; R 4  and R 6 , together with the atoms to which they are attached, form a ring selected from cycloalkyl, saturated or unsaturated heterocycle, aryl, and heteroaryl rings optionally substituted with at least one substituent R 16 ; p is 1 and m is 0, 1 or 2; A is phenyl; each R is independently halogen, lower alkyl, or lower alkoxy; and the R 4 \u2014R 6  ring is of formula: wherein Q is \u2014CH 2 \u2014; J is \u2014CH 2 \u2014; and d and b are each independently 0, or an integer of 1-4; or\n (vii) S/D is a double bond and R 5  and R 7  are absent; R 4  and R 6 , together with the atoms to which they are attached, form a ring selected from cycloalkyl, saturated or unsaturated heterocycle, aryl, and heteroaryl rings optionally substituted with at least one substituent R 16 ; p is 1 and m is 0, 1 or 2; A is phenyl; each R 2  is independently halogen, lower alkyl, or lower alkoxy; and the R 4 \u2014R 6  ring is of formula: \n wherein Q is \u2014CH 2 \u2014; J is \u2014CH 2 \u2014; and d and b are each independently 0, or an integer of 1-4; and R 1  is H, halogen, alkoxy, heteroalkyl, alkyl, alkenyl, cycloalkyl, aryl, saturated or unsaturated heterocyclyl, heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heteroaryl, aryl, and saturated or unsaturated heterocyclyl are optionally substituted with at least one substituent R 16 ; or\n (viii) S/D is a single bond; p is 1 and m is 0, 1 or 2; A is phenyl; each R 2  is independently halogen, lower alkyl, or lower alkoxy; or \n (ix) S/D is a single bond; p is 1 and m is 0, 1 or 2; A is phenyl; each R 2  is independently halogen, lower alkyl, or lower alkoxy, and R 1  is H, halogen, alkoxy, heteroalkyl, alkyl, alkenyl, cycloalkyl. aryl, saturated or unsaturated heterocyclyl, heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heteroaryl, aryl, and saturated or unsaturated heterocyclyl are optionally substituted with at least one substituent R 16 ; and R 16  is halogen, lower alkyl, or lower alkoxy; or \n (x) S/D is a single bond; p is 0 and R 6  and R 7  are absent; A is phenyl; and each R 2  is independently halogen, lower alkyl, or lower alkoxy; or \n (xi) S/D is a single bond; p is 0 and R 6  and R 7  are absent; A is phenyl; and each R 2  is independently halogen, lower alkyl, or lower alkoxy, and R 1  is H, halogen, alkoxy, heteroalkyl, alkyl, alkenyl, cycloalkyl, aryl, saturated or unsaturated heterocyclyl, heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heteroaryl, aryl, and saturated or unsaturated heterocyclyl are optionally substituted with at least one substituent R 16 .

Metadata:
- Claim Count in Document: 46.0
- Percentile: 93.0
- Lexical Diversity: 1.39535
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14951494', '14723417', '15359871', '14349144', '11399484']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8162841698366373
- 35 USC 102 Novelty (BERT): 0.5941048256460657
- Combined Prediction Score: 0.7940662354175801
- Mean Citation Score: 461.024532
- Max Citation Score: 532.4433
- Similarity Product: 435.95487990741134

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test