PATENT CLAIM ANALYSIS

Application Number: 15990561
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "093210"]

Abstract:
Provided herein are modified T lymphocytes comprising chimeric receptors and methods of use thereof.

Claim (Index 1):
A modified T lymphocyte comprising:\n a. a first polypeptide comprising a first extracellular antigen binding domain that binds a first antigen, and a first intracellular signaling domain, wherein said first polypeptide does not comprise a co-stimulatory domain; and b. a second polypeptide comprising a second extracellular antigen binding domain binding a second antigen, or a receptor that binds said second antigen; and a second intracellular signaling domain; wherein said modified lymphocyte becomes maximally cytotoxic only when said first signaling domain and said second signaling domain are both activated by said first antigen and said second antigen, respectively.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 93.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14653650', '14775891', '15550645', '14873836', '14516880']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7236284717953259
- 35 USC 102 Novelty (BERT): 0.563010304936326
- Combined Prediction Score: 0.7075666551094258
- Mean Citation Score: 390.335344
- Max Citation Score: 464.99088
- Similarity Product: 316.25142249200815

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test