PATENT CLAIM ANALYSIS

Application Number: 16300086
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "461000"]

Abstract:
The present disclosure relates to a compound having the activity of promoting osteoblast differentiation and inhibiting adipocyte differentiation and a preparation method thereof. The novel compound of the present disclosure increases the expression of the gene ALP involved in the differentiation of osteoblasts, regulates expression of the genes PPARγ, aP2 and CD36 involved in the differentiation of adipocytes, increases bone mineral density (BMD) in an ovariectomized osteoporosis animal model and decreases adipocytes in the bone marrow. Therefore, it can be used as an active ingredient of a medication or a health functional food useful for metabolic bone disease or obesity.

Claim (Index 14):
A method for preparing a compound of Chemical Formula 7 having the activity of promoting osteoblast differentiation and inhibiting adipocyte differentiation, comprising: a step of preparing a compound of Chemical Formula 6 by reacting a compound of Chemical Formula 4 with a compound of Chemical Formula 5; and a step of removing the MOM protecting group from the compound of Chemical Formula 6:

Metadata:
- Claim Count in Document: 26.0
- Percentile: 98.0
- Lexical Diversity: 1.62687
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10687220', '13885089', '14399726', '14745772', '12745888']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6793309266408789
- 35 USC 102 Novelty (BERT): 0.5351638747720396
- Combined Prediction Score: 0.664914221453995
- Mean Citation Score: 297.8990500000001
- Max Citation Score: 345.2581
- Similarity Product: 243.1178405578613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test