PATENT CLAIM ANALYSIS

Application Number: 16322312
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-06
Patent Classification: ["424", "450000"]

Abstract:
The present invention provides a way to capture a biomolecule such as a protein in one or more layers of covalently bonded amorphous silica, forming a cage or shell which preserves the shape of the protein and prevents denaturation caused by heat and/or aging and/or non-physiological conditions, through unfolding and loss of secondary and/or higher order structure.

Claim (Index 53):
The method according to  claim 51 , wherein the release solution comprises a fluoride ion concentration of from about 75 mM to about 150 mM, optionally the fluoride ion concentration is from about 75 mM to about 125 mM, further optionally the fluoride ion concentration is from about 85 mM to about 115 mM, or wherein the release solution has a pH of less than or equal to 6.0, preferably is less than 5.5, or is less than 5.0; or wherein the pH of the release solution is adjusted to about pH 5.0 or about 4.0.

Metadata:
- Claim Count in Document: 75.0
- Percentile: 99.0
- Lexical Diversity: 1.25
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10814123', '14111305', '14650645', '11721728', '14374388']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7067695386577115
- 35 USC 102 Novelty (BERT): 0.4806299636092537
- Combined Prediction Score: 0.6841555811528658
- Mean Citation Score: 131.735926
- Max Citation Score: 144.53966
- Similarity Product: 97.57088010836122

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test