PATENT CLAIM ANALYSIS

Application Number: 16195411
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-06
Patent Classification: ["514", "110000"]

Abstract:
Disclosed herein are compositions and methods for monitoring hematopoietic reconstitution or suppression in a subject. Also disclosed are compositions and methods for reconstituting the hematopoietic compartment of a subject in need thereof. Also disclosed is a method for monitoring the effect of ionizing radiation on the lung in a subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to guide therapy of the subject. Also disclosed is the ability to use detection of the one or more microRNA indicative of radiation-induced lung injury to evaluate the efficacy of a lung treatment following radiation exposure.

Claim (Index 3):
A method for reconstituting the hematopoietic compartment of a subject in need thereof, the method comprising:\n administering to the subject a therapeutically effective amount of a population of hematopoietic stem cells to reconstitute the hematopoietic compartment of the subject; and monitoring efficacy of the hematopoietic reconstitution by quantifying the levels of circulating miR-150 in a blood sample from the subject, wherein the levels of circulating miR-150 in the sample is an indication of hematopoietic reconstitution.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 98.0
- Lexical Diversity: 2.29167
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15310594', '14120289', '15846962', '13230673', '15318646']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7998347004697418
- 35 USC 102 Novelty (BERT): 0.7210393732766777
- Combined Prediction Score: 0.7919551677504354
- Mean Citation Score: 529.0770160000002
- Max Citation Score: 799.8791
- Similarity Product: 774.6648057700038

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test