PATENT CLAIM ANALYSIS

Application Number: 15772893
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "082000"]

Abstract:
The present invention provides compositions and methods for providing controllable local delivery of a conjugate of chloroquine (CQ) and a bisphosphonate to treat diseases characterized by abnormal bone metabolism. In certain embodiments, the invention is used as a treatment for a subject with diseases and disorders characterized by bone loss.

Claim (Index 12):
A composition for controlled local delivery of a therapeutic agent to bone, the composition comprising at least one compound comprising a therapeutic agent tethered to a phosphonate moiety via a linker, wherein the therapeutic agent is chloroquine (CQ) or an analogue thereof.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 93.0
- Lexical Diversity: 1.30952
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13646143', '12588882', '14620700', '15621665', '10576228']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7580665988127621
- 35 USC 102 Novelty (BERT): 0.533664401043891
- Combined Prediction Score: 0.7356263790358749
- Mean Citation Score: 322.2473619999999
- Max Citation Score: 323.93375
- Similarity Product: 174.10072831526398

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test