PATENT CLAIM ANALYSIS

Application Number: 16360995
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-09
Patent Classification: ["514", "653000"]

Abstract:
The inventive subject matter provides ready-to-administer, preferably anti-oxidant free, epinephrine compositions with improved stability, and methods for preparing the same. Contemplated compositions can be packaged using blow-fill-seal technology or packaged into flexible IV bags and maintain degradation of the epinephrine at a level of less than 5 wt % when stored over at least one months at between 2-40° C.

Claim (Index 1):
An antioxidant-free and storage stable ready-to-inject epinephrine composition, consisting essentially of:\n an aqueous pharmaceutically acceptable carrier containing epinephrine; wherein the epinephrine is present in the ready-to-inject epinephrine composition at a concentration of equal or less than 0.07 mg/ml; wherein substantially all of the epinephrine is an R-isomer; wherein the ready-to-inject epinephrine composition has a pH of between 3.0-4.7; wherein the ready-to-inject epinephrine composition further comprises a metal ion chelator selected from the group consisting of EDTA, edetic acid, EGTA and diethylenetriaminepentaacetic acid; and wherein the ready-to-inject epinephrine composition has, after storage of at least one month, total impurities of equal or less than 0.7% and equal or less than 2% S-isomer content.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 99.0
- Lexical Diversity: 1.2037
- Patent Class: 514.0
- Transitional Phrase Type: half
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16163476', '15883798', '16239465', '15949736', '16239461']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7966694999820758
- 35 USC 102 Novelty (BERT): 0.5142821915692326
- Combined Prediction Score: 0.7684307691407916
- Mean Citation Score: 268.43149400000004
- Max Citation Score: 272.81583
- Similarity Product: 180.65448897106108

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test