PATENT CLAIM ANALYSIS

Application Number: 15976450
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "489000"]

Abstract:
The present invention relates to methods of forming miniemulsions and use of the miniemulsions as a delivery system for bioactive agents. In particular, the present invention relates to methods for forming a miniemulsion comprising providing a first phase comprising a hydrophilic surfactant, lipophillic surfactant and water and a second phase comprising a lipid, wherein said miniemulsion comprises emulsified particles having a mean diameter of 1 μm or less.

Claim (Index 1):
A method for forming a delivery system for a lipophilic bioactive agent comprising the following sequential steps;\n a. preparing a first phase by:\n (i) dissolving a hydrophilic surfactant in water above critical micelle concentration (CMC) to produce an aqueous phase; and then \n (ii) dispersing lipophilic surfactant in said aqueous phase to produce said first phase which first phase contains micelles of hydrophilic surfactant and lipophilic surfactant and comprises a multi-lamellar structure; \n b. preparing a second phase comprising lipid and a lipophilic bioactive agent; and c. adding the second phase to the first phase drop-wise or as a continuous flow or continuous stream during continuous mixing at a speed of between about 5,000 rpm and about 20,000 rpm, at a temperature of 40\u00b0 C. or less and at an atmospheric pressure of less than 1,000 kPa to form a miniemulsion comprising between about 0.5% w/w and about 5% w/w hydrophilic surfactant, between about 1% w/w and about 5% w/w lipophilic surfactant, between about 0.5% w/w and about 25% w/w lipid, and between about 0.2% w/w and about 5% w/w lipophilic bioactive agent; and wherein said delivery system comprises emulsified particles having a mean diameter of between 250 nm and 1 \u03bcm which are stable for 3 months or more between 2\u00b0 C. and 30\u00b0 C.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 1.58696
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13992435', '13604610', '15547490', '13767734', '15411753']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6510056949000426
- 35 USC 102 Novelty (BERT): 0.5786454961889516
- Combined Prediction Score: 0.6437696750289336
- Mean Citation Score: 235.00834
- Max Citation Score: 456.7555
- Similarity Product: 417.83706744349

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test