PATENT CLAIM ANALYSIS

Application Number: 15917549
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["435", "006110"]

Abstract:
The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Claim (Index 4):
The system of  claim 3 , wherein the RxxxxH motif comprises a R[N/H/K]X 1 X 2 X 3 H sequence, wherein X 1  is R, S, D, E, Q, N, G, or Y, and X 2  is independently I, S, T, V, or L, and X 3  is independently L, F, N, Y, V, I, S, D, E, or A.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.38889
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15917546', '15467922', '15916271', '14975085', '15897089']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6722927405041794
- 35 USC 102 Novelty (BERT): 0.6612100506819094
- Combined Prediction Score: 0.6711844715219525
- Mean Citation Score: 415.336298
- Max Citation Score: 717.7631
- Similarity Product: 608.5832275913477

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test