PATENT CLAIM ANALYSIS

Application Number: 15566955
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-10
Patent Classification: ["514", "255010"]

Abstract:
This invention relates to a derivative of the general formula (I), as follows: or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof for use as a medicament for the treatment and/or prevention of muscle atrophy in mammals and/or for limiting muscular atrophy in mammals and/or to promote muscle growth in exercising mammals aimed at increasing muscle mass and quality, preventing the occurrence of symptoms of sarcopenia related to age or rehabilitation after a muscle loss, age-related muscle atrophy and/or the consequences of drug therapy and/or immobilization and/or cachexia.

Claim (Index 1):
Derivative of general formula I below: in which\n R 1  and R 2  independently from each another are hydrogen or (C 1 -C 6 ) alkyl, preferably a methyl; \n n is an integer between 1 and 2, preferably n=1; \n R 3  represents\n an \u2014OH group; \n an \u2014O(C 1 -C 6  alkyl) group, advantageously \u2014OEt or \u2014OiPr; \n an \u2014O (C 3 -C 6  cycloalkyl) group, advantageously an \u2014O-cyclopentyl; \n an \u2014O (C 3 -C 7  heterocyclic) group, advantageously an \u2014O-tetrahydropyran-4-yl; \n an \u2014O-heteroaryl group, advantageously an \u2014O-pyridyl; \n an \u2014O-aryl group, advantageously an \u2014O-phenyl; \n an \u2014O(C 1 -C 6  alkyl) aryl group, advantageously \u2014O-benzyl; \n an \u2014NR 7 R 8  group, in which \n \n R 7  represents a hydrogen atom or a C 1 -C 6  alkyl group and R 8  represents\n a hydrogen atom; \n a heteroaryl group, advantageously containing one or more nitrogen atoms; \n a C 1 -C 6  alkyl group, advantageously an ethyl group, optionally substituted with an \u2014NR 9 R 10  group in which R 9  and R 10  represent, independently of one another, a hydrogen atom or a C 1 -C 6  alkyl group, advantageously a group methyl; \n a C 1 -C 6  alkyl group, advantageously an ethyl group, optionally substituted with a group \u2014OR 10  in which R 11  represents a hydrogen atom or a C 1 -C 6  alkyl group, advantageously a methyl group; \n \n or R 7  and R 8  form with the nitrogen atom which provides them with a heterocycle, in particular a pyrrolidine, a piperidine, a morpholine, a piperazine, the heterocycle being optionally substituted with a C 1 -C 6  alkyl group, advantageously a methyl group; \n R 4  represents a hydrogen atom or a C 1 -C 6  alkyl group, in particular -Me or -Et; \n R 5  and R 6  represent, independently from each other, a hydrogen atom, a halogen atom, advantageously Cl, or a group chosen from: a \u2014CN group; \n an \u2014OH group; \n an \u2014O(C 1 -C 6 ) alkyl group, advantageously \u2014OMe, the alkyl group being optionally substituted by one or more halogen atoms, advantageously F; \n a C 1 -C 6  alkyl group, advantageously methyl, optionally substituted with one or more halogen atoms, advantageously F; \n an \u2014O (C 3 -C 6  cycloalkyl) group, advantageously an \u2014O-cyclopropyl; \n or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof for use as a medicament for the treatment and/or prevention of muscle atrophy in mammals and/or for limiting muscular atrophy in mammals and/or to promote muscle growth in exercising mammals aimed at increasing muscle mass and quality, preventing the occurrence of symptoms of sarcopenia related to age or rehabilitation after a muscle loss, age-related muscle atrophy and/or the consequences of drug therapy and/or immobilization and/or cachexia.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 88.0
- Lexical Diversity: 1.56716
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15311967', '12919007', '13194434', '12281309', '14335853']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7819995081566372
- 35 USC 102 Novelty (BERT): 0.5089132933784241
- Combined Prediction Score: 0.754690886678816
- Mean Citation Score: 211.535924
- Max Citation Score: 261.41336
- Similarity Product: 180.21624023767475

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test