PATENT CLAIM ANALYSIS

Application Number: 15742874
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-03
Patent Classification: ["530", "387300"]

Abstract:
The present invention relates to the preparation of an antibody analogue capable of being activated reversibly, and uses thereof, and provides a fusion protein comprising an inactive first fragment of an antibody analogue is fused to a stimulus-induced dimerization protein.

Claim (Index 21):
A method for activating the antibody analogue in a subject, tissue or cell, the method comprising:\n introducing a first fusion protein comprising an inactive first fragment of an antibody analogue is fused to a stimulus-induced dimerization protein, and a second fusion protein comprising an inactive second fragment of an antibody analogue is fused to a stimulus-induced dimerization partner protein which forms a dimer with the stimulus-induced dimerization protein upon stimulation, wherein the inactive second fragment recovers antigen-binding capacity when bound to the inactive first fragment by dimerizing of the stimulus-induced dimerization protein and the stimulus-induced dimerization partner protein induced by a stimulus to the subject, tissue, or cell; and applying the stimulus to the subject, tissue or cell, wherein the stimulus induces dimerization of the stimulus-induced dimerization protein and the stimulus-induced dimerization partner protein.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 1.34375
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10226949', '15311198', '14004879', '15190337', '15618770']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6682289917081827
- 35 USC 102 Novelty (BERT): 0.5028929925000957
- Combined Prediction Score: 0.651695391787374
- Mean Citation Score: 262.46429
- Max Citation Score: 274.88907
- Similarity Product: 202.71750274631023

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test