PATENT CLAIM ANALYSIS

Application Number: 16230576
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-07
Patent Classification: ["514", "171000"]

Abstract:
A method of promoting remyelination in a subject in need thereof includes administering to the subject a therapeutically effective amount of at least one (1,3) Diazole compound, wherein the therapeutically effective amount is the amount effective to induce endogenous oligodendrocyte precursor cell (OPC) differentiation in the subject's central nervous system.

Claim (Index 16):
The method of  claim 1 , further comprising administering to the subject a compound having the formula (II): wherein:\n (a) R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , R 16 , R 17  are each individually hydrogen, a substituted or unsubstituted C 1 -C 24  alkyl, C 2 -C 24  alkenyl, C 2 -C 24  alkynyl, C 3 -C 20  aryl, heteroaryl, heterocycloalkenyl containing from 5-6 ring atoms (wherein from 1-3 of the ring atoms is independently selected from N, NH, N(C 1 -C 6  alkyl), NC(O)(C 1 -C 6  alkyl), O, and S), C 6 -C 24  alkaryl, C 6 -C 24  aralkyl, halo, \u2014Si(C 1 -C 3  alkyl) 3 , hydroxyl, sulfhydryl, C 1 -C 24  alkoxy, C 2 -C 24  alkenyloxy, C 2 -C 24  alkynyloxy, C 5 -C 20  aryloxy, acyl, acyloxy, C 2 -C 24  alkoxycarbonyl, C 6 -C 20  aryloxycarbonyl, C 2 -C 24  alkylcarbonato, C 6 -C 20  arylcarbonato, carboxy, carboxylato, carbamoyl, C 1 -C 24  alkyl-carbamoyl, arylcarbamoyl, thiocarbamoyl, carbamido, cyano, isocyano, cyanato, isocyanato, isothiocyanato, azido, formyl, thioformyl, amino, C1-C 24  alkyl amino, C 5 -C 20  aryl amino, C 2 -C 24  alkylamido, C 6 -C 20  arylamido, imino, alkylimino, arylimino, nitro, nitroso, sulfo, sulfonato, C 1 -C 24  alkylsulfanyl, arylsulfanyl, C 1 -C 24  alkylsulfinyl, C 5 -C 20  arylsulfinyl, C 1 -C 24  alkylsulfonyl, C 5 -C 20  arylsulfonyl, phosphono, phosphonato, phosphinato, phospho, or phosphino or combinations thereof, and wherein R 10  and R 11  may be linked to form a cyclic or polycyclic ring, wherein the ring is a substituted or unsubstituted aryl, heteroaryl, cycloalkyl, or heterocyclyl; \n (b) the ABCD ring structure and/or one or more methyl group are independently optionally substituted with one or more substituents selected from C 1 -C 6 -alkyl, halogenated C 1 -C 6 -alkyl, C 1 -C 6 -alkenyl, halogenated C 1 -C 6 -alkenyl, halogen, amino, aminoalkylene, hydroxyimino, carbonyl (oxo), and hydroxy; \n (c) X is OH or O; and \n (d) dashed lines are taken at each occurrence independently to be double or single bonds; and combinations thereof, or pharmaceutically acceptable salts thereof.

Metadata:
- Claim Count in Document: 54.0
- Percentile: 98.0
- Lexical Diversity: 1.425
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14723008', '15418572', '13985342', '13426364', '14973105']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7521357162051113
- 35 USC 102 Novelty (BERT): 0.6701851303256727
- Combined Prediction Score: 0.7439406576171674
- Mean Citation Score: 368.097614
- Max Citation Score: 663.5061599999998
- Similarity Product: 651.0336545070646

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test