PATENT CLAIM ANALYSIS

Application Number: 15757196
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["435", "006110"]

Abstract:
Methods of labeling, identifying and differentiating microorganisms using functionalized Buckyballs are provided herein. The invention further provides methods for imaging or inhibiting gene expression using functionalized Buckyballs of the invention. The invention also provides a system for labeling, identifying and differentiating microorganisms.

Claim (Index 46):
A system for labelling, identifying and differentiating living microorganisms of different species within a sample, the system comprising:\n a) one or more source wells and one or more sink wells, wherein the source wells and the sink wells are in fluidic communication with each other; b) one or more functionalized Buckminsterfullerene molecules for each species of microorganism in the sample, wherein the Buckminsterfullerene molecules are functionalized with one or more RNA oligonucleotides complementary to one or more species specific signature RNA sequences of the microorganisms in the sample, wherein the one or more RNA oligonucleotides are hybridized to protecting layers comprising segments of DNA or RNA and a detectable label; wherein, the detectable label is not detected when the protecting layers are hybridized to the one or more RNA oligonucleotides and the detectable label is detected when the protecting layers are not hybridized; and wherein, each sink well comprises a different type of functionalized Buckminsterfullerene molecule, bound to a different detectable label, each corresponding to a different microorganism species; and wherein the microorganisms are labeled, identified and differentiated by: a) placing a sample comprising one or more different species of microorganisms in the source well; b) allowing the microorganisms to migrate to the one or more sink wells, coming in contact with and internalizing the one or more functionalized Buckminsterfullerene molecules; and wherein the microorganisms emit a signal if in contact with a Buckminsterfullerene molecule comprising an RNA oligonucleotide which matches a species specific signature RNA sequence within the microorganism.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 1.56667
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['10912556', '13518211', '11810834', '13707295', '11746374']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5563953514872818
- 35 USC 102 Novelty (BERT): 0.4848598057356437
- Combined Prediction Score: 0.5492417969121179
- Mean Citation Score: 192.591418
- Max Citation Score: 209.19748
- Similarity Product: 161.1959487481833

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test