PATENT CLAIM ANALYSIS

Application Number: 15780509
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "04400A"]

Abstract:
Inhibitory nucleic acids, e.g., antisense oligonucleotides (ASO) against PAR-TERRA RNA or other chromosome-specific TERRA transcripts (i.e., inclusive of chromosome-specific subtelomeric sequences), and methods of use thereof to downregulate expression of escapee genes on the inactive X chromosome, expression from the active X chromosome, subtelomeric autosomal loci (e.g., FSHD locus), or expression of autosomal genes involved in growth control and apoptosis, e.g., in cells and subjects with supernumerary X chromosomes and/or cancer and other human diseases.

Claim (Index 21):
The method of  claim 1 , wherein one or more of the nucleotides of the inhibitory nucleic acid comprise one of both of ENA nucleotide analogues or LNA nucleotides.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 93.0
- Lexical Diversity: 1.58621
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12812489', '14419763', '15171883', '15171706', '15050273']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7642365452851663
- 35 USC 102 Novelty (BERT): 0.5196024190795885
- Combined Prediction Score: 0.7397731326646085
- Mean Citation Score: 271.905502
- Max Citation Score: 328.20355
- Similarity Product: 284.2204976504922

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test