PATENT CLAIM ANALYSIS

Application Number: 16138369
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "252030"]

Abstract:
The present invention aims to provide a compound having a TrkA inhibitory action, a pharmaceutically acceptable salt thereof, or a solvate thereof, a pharmaceutical composition containing the same as an active ingredient, and a preventive and/or therapeutic agent for medicinal use, in particular for a disease in which TrkA in involved (pain, cancers, inflammation/inflammatory diseases, allergic diseases, skin diseases, neurodegenerative diseases, infectious diseases, Sjogren's syndrome, endometriosis, renal diseases, osteoporosis, and the like). Specifically, the present invention provides a compound or an optical isomer thereof, a pharmaceutically acceptable salt thereof, a solvate thereof, or the like, the compound represented by formula (I):

Claim (Index 30):
The method according to  claim 28 , wherein said at least one of a compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, or an optical isomer thereof, is administered in combination with one or more drugs selected from the group consisting of opioid agonists, pyrin-based antipyretics and analgesics, non-pyrin-based antipyretics and analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), COX-2 selective inhibitors, peripheral neuropathic pain/fibromyalgia drugs, descending pain modulatory drugs, antiepileptics, antidepressants, antiarrhythmics, NMDA receptor antagonists, bisphosphonates, vanilloid receptor agonists, sodium channel modulators, fatty acid amide hydrolase (FAAH) inhibitory active compounds, barbiturate sedatives, benzodiazepines having a sedative action, H1 antagonists, 5-HT receptor agonists or antagonists, microsomal prostaglandin E synthase type 1 (mPGES-1) inhibitors, leukotriene B4 antagonists, \u03b12-\u03b4 ligands, metabotropic glutamate subtype 1 receptor (mGluR1) antagonists, prostaglandin E2 subtype 4 (EP 4) antagonists, diabetes treatment drugs, anti-obesity drugs, antihyperlipidemic agents such as cholesterol lowering drugs, antihypertensive agents, disease modifying anti-rheumatic drugs (DMARDs), anti-cytokine drugs, sexual hormones or derivatives thereof, parathyroid hormone (PTH), GABA B  receptor agonists, steroid drugs, a-adrenergic agonists, \u03b12-adrenergic receptor agonists, sedatives, skeletal muscle relaxants, anticonvulsant drugs, tachykinin (NK) antagonists including NK 3, NK-2, and NK-1 antagonists, muscarinic antagonists, coal tar analgesics, neuroleptics, T2A receptor antagonists, 5-HT3 antagonists, cholinergic (nicotinic) analgesics, PDEV inhibitors, nitric oxide synthase (iNOS) inhibitors, acetylcholinesterase inhibitors, 5-lipoxygenase inhibitors, anti-TNF therapy, antimetabolites and antifolates, targeted kinase inhibitors, anticonvulsant agents, calcitonin gene-related peptide receptor (CGRP) antagonists, tyrosine kinase targeted therapeutic agents, Ras-Raf-MEK-ERK pathway inhibitors, PI3K-Akt-mTOR-S6K pathway inhibitors, apoptosis regulators and signal transduction pathway inhibitors, cytotoxic chemotherapeutic drugs, angiogenesis targeted therapeutic drugs, immune targeted drugs, NGF targeted biopharmaceuticals, and pan-Trk inhibitors.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 97.0
- Lexical Diversity: 1.89706
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11988659', '13392350', '13008456', '14442609', '14601775']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7922972568189076
- 35 USC 102 Novelty (BERT): 0.5273894306417006
- Combined Prediction Score: 0.7658064742011869
- Mean Citation Score: 301.63904999999994
- Max Citation Score: 317.48358
- Similarity Product: 208.6361608203364

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test