PATENT CLAIM ANALYSIS

Application Number: 16327972
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["552", "508000"]

Abstract:
The present invention discloses a process for the preparation of pregnadiene derivatives having formula I, their stereoisomer and intermediate thereof. Formula I wherein each substituent is independently, R 1  and R 2  is hydrogen or C 1 -C 8  straight, branched alkyl chain, saturated or unsaturated cycloalkyl; R 3  is hydrogen or wherein R 5  represents C 1 -C 8  straight, branched alkyl chain or cycloalkyl; R 4  is hydrogen or halogen; R 6  is hydrogen or halogen;

Claim (Index 3):
The process as claimed in  claim 1 , wherein the compound of Formula (1) is\n i. (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one; ii. 6\u03b1,9-difluoro-11\u03b2,16\u03b1,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone,21-acetate; iii. 1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one; iv. ((16,17-(butylidenebis(oxy))-11,21-dihydroxy-, (11-\u03b2,16-\u03b1)-pregna-1,4-diene-3,20-dione v. 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9, 13-dimethyl-16-oxo-5, 7-dioxapentacyclo [10.8.0.02,9.04, 8.013,18] icosa-14, 17-dien-8-yl]-2-oxoethyl 2-methylpropanoate. vi. (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one vii. (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2\u2032,1\u2032:4,5]indeno[1,2-d][1,3]dioxol-2-one viii. 2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12\u2032-fluoro-11\u2032-hydroxy-9\u2032,13\u2032-dimethyl-16\u2032-oxo-5\u2032,7\u2032-dioxaspiro[cyclopentane-1,6\u2032 pentacyclo[10.8.0.02,9.04,8.013,18]icosane]-14\u2032,17\u2032-dien-8\u2032-yl]-2-oxoethyl acetate; ix. (11\u03b2,16\u03b1)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; x. (11\u03b2,16\u03b1)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione

Metadata:
- Claim Count in Document: 17.0
- Percentile: 99.0
- Lexical Diversity: 1.76
- Patent Class: 552.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15543862', '12061499', '14354478', '12666423', '15548713']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6635996219450734
- 35 USC 102 Novelty (BERT): 0.5808726491494048
- Combined Prediction Score: 0.6553269246655065
- Mean Citation Score: 223.41237400000003
- Max Citation Score: 277.79678
- Similarity Product: 218.20809294392345

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test