PATENT CLAIM ANALYSIS

Application Number: 15869865
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["544", "106000"]

Abstract:
Amides substituted with aromatic groups were synthesized and some were purified to create enantiomer pure compounds. The compounds were tested to determine their ability to inhibit the growth of bacteria and the formation of biofilms created by bacteria. Some of these compounds were found to be effective antibacterials and to effectively inhibit the formation of biofilms.

Claim (Index 7):
A method for reducing the growth of bacteria, comprising the steps of:\n treating bacteria with at least one compound comprising the formula: wherein:\n R 1  is selected from the group consisting of: biphenyl, \u2014(CH 2 ) n -biphenyl, biphenyl ketone, naphthalene, anthracene, benzyl optionally substituted with 1 to 3 halogens, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, \u2014NH 2 \u2014NO 2 , \u2014CN, or \u2014CF 3 , and phenyl optionally substituted with 1 to 3 halogens, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, \u2014NH 2 \u2014NO 2 , \u2014CN, or \u2014CF 3 ; \n R 2  is selected from the group consisting of: \u2014OH, \u2014NH 2 , \u2014NHR 3 , and \u2014NR 3 R 4 ; \n R 3  and R 4  are independently selected from the group consisting of: H, halogen, \u2014NH 2 \u2014NO 2 , C 1 -C 6  alkyl being unbranched, branched or cyclic, C 1 -C 6  alkoxy, C 1 -C 6  haloalkoxy, hydroxyl, acyl, acyl amides, carboxyl, tetrazolyl, and \u2014(CH 2 ) n \u2014R 5 ; \n alternatively, R 3  and R 4  are taken together to form a pyridine, a piperidine, a pyrrolidine, or a pyrrole ring; \n R 5  is \u2014OH, \u2014CF 3 , morpholinyl, pyridinyl, benzyl optionally substituted with 1 to 3 halogens, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, \u2014NH 2 \u2014NO 2 , \u2014CN, or \u2014CF 3 , or phenyl optionally substituted with 1 to 3 halogen, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, \u2014OH, \u2014NH 2 , \u2014NO 2 , \u2014CN, or \u2014CF 3 ; and \n n is 1, 2, 3, or 4; \n or a pharmaceutically acceptable salt thereof, or a metabolite thereof.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 86.0
- Lexical Diversity: 1.59459
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15335156', '15711648', '13188790', '11662806', '15222734']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7641511171945344
- 35 USC 102 Novelty (BERT): 0.5020256124351161
- Combined Prediction Score: 0.7379385667185926
- Mean Citation Score: 281.142606
- Max Citation Score: 297.50443
- Similarity Product: 248.3625336798472

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test