PATENT CLAIM ANALYSIS

Application Number: 15906054
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["514", "04400A"]

Abstract:
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a RRM2 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a RRM2 gene using said pharmaceutical composition; and methods for inhibiting the expression of RRM2 in a cell.

Claim (Index 3):
The double-stranded ribonucleic acid molecule of  claim 2 , wherein the modified nucleotide is selected from the group consisting of: 2\u2032-O-methyl modified nucleotide, nucleotide comprising a 5\u2032-phosphorothioate group, 2\u2032-deoxy-2\u2032-fluoro modified nucleotide, 2\u2032-deoxy-modified nucleotide, locked nucleotide, abasic nucleotide, inverted deoxythymidine, 2\u2032-amino-modified nucleotide, 2\u2032-alkyl-modified nucleotide, morpholino nucleotide, phosphoramidate, and non-natural base comprising nucleotide.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 88.0
- Lexical Diversity: 1.68889
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15415415', '13275377', '13612521', '15387470', '14156193']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7941186511668533
- 35 USC 102 Novelty (BERT): 0.6128734098910937
- Combined Prediction Score: 0.7759941270392774
- Mean Citation Score: 420.926618
- Max Citation Score: 574.9729
- Similarity Product: 500.22817356551286

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test