PATENT CLAIM ANALYSIS

Application Number: 15917973
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["546", "089000"]

Abstract:
The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. For Formula I compounds X, Y, R 1 , R 2 , R 3a , R 3b , R 4a , R 4b  and R 5  are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.

Claim (Index 6):
The method according to  claim 1  wherein R 3a , R 3b , R 4a  and R 4b  independently are H, halogen, C 1 -C 8 (alkyl), (C 1 -C 8 )haloalkyl, OH, CN, [(C 1 -C 8 )alkylene]OR 9 , [(C 1 -C 8 )alkylene]NHR 9 , [(C 1 -C 8 )alkylene]NR 9 R 9 , C(O)NH 2 , C(O)NHR 9 , C(O)NR 9 R 9 , C(O)R 9 , CO 2 R 9 , C(S)NH 2 , S(O)R 9 , SO 2 R 9 , SO 2 NHR 9 , SO 2 NR 9 R 9 , heteroaryl or cycloalkyl, wherein R 9  is a C 1 -C 8 (alkyl) or (C 1 -C 8 )haloalkyl, or wherein the two R 9 's together with the nitrogen atom to which they are attached of [(C 1 -C 8 )alkylene]NR 9 R 9 , C(O)NR 9 R 9  or SO 2 NR 9 R 9 , optionally form a heterocyclyl ring.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 90.0
- Lexical Diversity: 1.62712
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15358761', '14772731', '15676726', '15108391', '10420390']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7440058646900389
- 35 USC 102 Novelty (BERT): 0.749058700810338
- Combined Prediction Score: 0.7445111483020689
- Mean Citation Score: 432.51935
- Max Citation Score: 864.5835599999997
- Similarity Product: 831.1158927408528

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test