PATENT CLAIM ANALYSIS

Application Number: 16067676
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "520000"]

Abstract:
Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer.

Claim (Index 1):
A compound of formula (i): and stereoisomers and pharmaceutically acceptable salts thereof, wherein n is an integer from 0 to 4; m is an integer from 0 to 4; X is H, hydroxy, or C 1-4  alkoxy; R 1  and R 2  are independently H, hydroxy, C 1-4  alkyl, C 1-4  alkoxy, amino, \u2014S\u2014C 1-4  alkyl, or halo; R 3  is H, hydroxy, oxo, cyano, halo, C 1-4  alkyl, or C 1-4  alkoxy; each R 4  is independently hydrogen, hydroxy, oxo, halo, C 1-4  alkyl, or C 1-4  alkoxy; R 5  is H, C 1-4  alkynyl, or is absent if a double bond is present; and  is an optional double bond.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 95.0
- Lexical Diversity: 1.65385
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15440396', '14886332', '13594223', '14790313', '13770706']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7359618491125254
- 35 USC 102 Novelty (BERT): 0.5175581098738691
- Combined Prediction Score: 0.7141214751886598
- Mean Citation Score: 294.405804
- Max Citation Score: 299.8177
- Similarity Product: 246.954034799552

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test