PATENT CLAIM ANALYSIS

Application Number: 15914587
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "450000"]

Abstract:
Provided are a pharmaceutical composition of an amorphous vortioxetine or a salt thereof, and a preparation method therefor. The pharmaceutical composition comprises an amorphous vortioxetine or a pharmaceutically acceptable salt thereof and two or more pharmaceutical excipients. The pharmaceutical composition has good stability and dispersity, and enhances the dissolution of vortioxetine or the pharmaceutically acceptable salt thereof, thereby improving the bioavailability of the medicinal formulation and the body absorption of the medicine.

Claim (Index 1):
A pharmaceutical composition comprising vortioxetine, or a pharmaceutically acceptable salt thereof, and two or more types of pharmaceutical excipients, wherein the weight ratio of vortioxetine or pharmaceutically acceptable salt thereof to total amount of the pharmaceutical excipients is 1:0.1\u02dc100, wherein the vortioxetine or pharmaceutically acceptable salt thereof in the pharmaceutical composition is in an amorphous form, wherein in X-ray powder diffraction pattern of the composition, no characteristic peaks of crystalline vortioxetine or pharmaceutically acceptable salt thereof are present after deducting background peaks of the pharmaceutical excipients.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 90.0
- Lexical Diversity: 1.95
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14916075', '15304929', '14429388', '15048868', '14902326']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7628170967492048
- 35 USC 102 Novelty (BERT): 0.5378917564784409
- Combined Prediction Score: 0.7403245627221285
- Mean Citation Score: 348.08949
- Max Citation Score: 392.5238
- Similarity Product: 268.19523594312665

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test