PATENT CLAIM ANALYSIS

Application Number: 15891649
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "032000"]

Abstract:
Certain embodiments of the invention are directed to evaluating and identifying cells by recording and interpreting a time-dependent signal produced by unique cell respiration and permeability attributes of isolated viable cells.

Claim (Index 1):
A method for detecting and characterizing microbes in a sample, the method comprising:\n (a) contacting a sample containing microbes with at least one reporter forming a sample mixture, wherein optical emissions of the reporter indicate microbial cell viability; (b) dividing the sample mixture into at least two portions, wherein a first portion is treated with an antimicrobial drug forming a test portion and the second portion is a control portion; (c) partitioning the test portion and the control portion into two-dimensional arrays of small volume partitions, wherein some of the small volume partitions have one microbe or one natural microbe aggregate per small volume partitions; (d) incubating the small volume partitions for a period of time at a specified temperature or series of temperatures; (e) monitoring optical emissions of the small volume partitions during the incubation time; (f) constructing an optical emission waveform for each small volume partitions based on the optical emissions of the small volume partitions over time resulting in a small volume partitions waveform; (g) identifying the microbes in the sample using the small volume partitions waveforms; and (h) determining susceptibility of the microbes in the sample to the antimicrobial drug by comparing waveforms for small volume partitions of the treated portion to waveforms of the small volume partitions of the control portion, wherein differences in the small volume partitions waveforms between the small volume partitions of the treated portion to small volume partitions of the control portion indicates susceptibility to the antimicrobial.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.18519
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15891616', '15466377', '15833629', '15891542', '15523131']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.600198152410329
- 35 USC 102 Novelty (BERT): 0.5590893430721942
- Combined Prediction Score: 0.5960872714765156
- Mean Citation Score: 364.303218
- Max Citation Score: 418.8554
- Similarity Product: 407.6888792745352

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test