PATENT CLAIM ANALYSIS

Application Number: 16270021
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-09
Patent Classification: ["514", "007600"]

Abstract:
This invention is directed to methods and compositions for increasing the expression or activity of neprilysin in, for example, the frontal cortex or the entorhinal cortex using a progranulin polypeptide or effector. The present invention is further directed to methods of reducing microglia in the brain of a patient with neurodegenerative disease using a progranulin polypeptide or effector.

Claim (Index 1):
A method for increasing the activity of neprilysin in the frontal cortex or entorhinal cortex of a patient with neurodegenerative disease, the method comprising the step of\n administering to the patient a composition comprising a progranulin polypeptide wherein the activity of neprilysin in the frontal cortex or entorhinal cortex of the patient is increased.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.63158
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15772810', '13129363', '12610815', '10512588', '13520390']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7406637474680696
- 35 USC 102 Novelty (BERT): 0.4971668518220988
- Combined Prediction Score: 0.7163140579034725
- Mean Citation Score: 217.49764
- Max Citation Score: 232.7031
- Similarity Product: 164.30485950089692

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test