PATENT CLAIM ANALYSIS

Application Number: 16184270
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["424", "139100"]

Abstract:
Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are usefule in the treatment of diseases associated with increased production of IFNα and IFNω.

Claim (Index 4):
The antibody of  claim 3 , wherein the antibody binds IFN\u03c9 with a dissociation constant (K D ) of between about 0.3\u00d710 \u22129  M and about 4.5\u00d710 \u22129  M, wherein the K D  is measured using SPR technology with ProteOn (Bio-Rad Hercules, Calif.), with antibody loaded on an antibody coupled chip for 2 minutes at a flow rate of 30 \u03bcl/min, washing with running buffer for 2 minutes at a flow rate of 50 \u03bcl/ml, and associating recombinant IFN proteins at 5 different concentrations ranging from 100 nM to 1.23 nM with 1:3 dilution were for 3 minutes and dissociating for 10 minutes, both at the flow rate of 50 \u03bcl/ml.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 98.0
- Lexical Diversity: 1.25806
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14208861', '15707317', '14745939', '12551250', '14902409']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7110304132158645
- 35 USC 102 Novelty (BERT): 0.5520943075327277
- Combined Prediction Score: 0.6951368026475508
- Mean Citation Score: 300.085278
- Max Citation Score: 397.9143
- Similarity Product: 326.0260315385878

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test