PATENT CLAIM ANALYSIS

Application Number: 16223332
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["424", "192100"]

Abstract:
The present invention relates, in part, to, chimeric proteins which include the extracellular domain of colony stimulating factor 1 receptor (CSF1R) and their use in the treatment of diseases, such as immunotherapies for cancer and/or an inflammatory disease.

Claim (Index 65):
A recombinant fusion protein comprising a general structure of:\n N terminus-(a)-(b)-(c)-C terminus, wherein:\n (a) is a first domain comprising an extracellular domain of CSF1R that is at least 95% identical to the amino acid sequence of SEQ ID NO: 2 and is capable of binding a CSF1R ligand, \n (b) is a linker linking the first domain and the second domain and comprising a hinge-CH2-CH3 Fc domain derived from human IgG4, and optionally one or more joining linker sequences independently selected from SEQ ID 28 to 74, and \n (c) is a second domain comprising an extracellular domain of CD40 ligand (CD40L) that is at least 95% identical to the amino acid sequence of SEQ ID NO: 4 and is capable of binding an CD40L receptor.

Metadata:
- Claim Count in Document: 49.0
- Percentile: 98.0
- Lexical Diversity: 1.15385
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16203469', '15853241', '16024226', '16024209', '16024214']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7988384371350968
- 35 USC 102 Novelty (BERT): 0.5728630585947624
- Combined Prediction Score: 0.7762408992810634
- Mean Citation Score: 470.10808
- Max Citation Score: 485.20197
- Similarity Product: 405.9227182597268

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test