PATENT CLAIM ANALYSIS

Application Number: 15957279
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "134100"]

Abstract:
Provided herein are specific GITR receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a GITRL-associated disease or disorder. The GITR receptor agonist proteins provided herein comprise three soluble GITRL domains and an Fc fragment. The GITR receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.

Claim (Index 15):
The GITR receptor agonist protein of  claim 14 , wherein the two polypeptides are covalently linked through three interchain disulfide bonds formed at:\n a) positions 406, 412 and 415 of SEQ ID NO: 27, 29, 30, or b) positions 392, 398 and 401 of SEQ ID NO: 31, or c) positions 391, 397 and 400 of SEQ ID NO: 32, or d) positions 374, 380 and 383 of SEQ ID NO: 33, or e) positions 397, 403 and 406 of SEQ ID NO: 34, or f) positions 382, 388 and 391 of SEQ ID NO: 35, or g) positions 394, 400 and 403 of SEQ ID NO 49, or h) positions 370, 376 and 379 of SEQ ID NO 50.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.4
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15636711', '15014134', '15234551', '15643787', '15217754']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7564615695801867
- 35 USC 102 Novelty (BERT): 0.543320904860179
- Combined Prediction Score: 0.735147503108186
- Mean Citation Score: 363.87054
- Max Citation Score: 380.20157
- Similarity Product: 251.1125954503429

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test