PATENT CLAIM ANALYSIS

Application Number: 15773466
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "04400A"]

Abstract:
A pharmaceutical composition can be provide for treating or preventing heart failure. Additionally, siRNA and a vector expressing said siRNA can be provided that can be used in the pharmaceutical composition for treating or preventing heart failure. For example, a pharmaceutical composition can be provided for treating or preventing heart failure that contains a DNA sequence encoding RNA containing a sense strand sequence of consecutive 18 to 29 nucleotides from angiopoietin-like protein 2 (ANGPTL2) mRNA or the alternative splicing type RNA thereof and an antisense strand sequence complementary to the sense strand sequence under control of a promoter, and a pharmaceutically acceptable carrier.

Claim (Index 29):
The pharmaceutical composition according to claim  1 , wherein the DNA sequence comprises the sense strand sequence, the antisense strand sequence and a sequence encoding a hairpin type RNA composed of a single strand loop sequence (hairpin sequence) bonding the sense strand sequence and the antisense strand sequence via a covalent bond,\n wherein the DNA sequence is adapted for use such that, when and the hairpin sequence is processed by Dicer, an intracellular RNase, siRNA comprising the sense strand sequence and the antisense strand sequence is formed.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 1.7619
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14342867', '12811306', '13702033', '12096216', '13389236']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7784897837986451
- 35 USC 102 Novelty (BERT): 0.5244982730423366
- Combined Prediction Score: 0.7530906327230142
- Mean Citation Score: 307.718864
- Max Citation Score: 339.27847
- Similarity Product: 246.579207943858

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test