PATENT CLAIM ANALYSIS

Application Number: 16254017
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["424", "001810"]

Abstract:
Disclosed herein are  18 F-labeled compounds and compositions thereof. Also disclosed are methods of imaging estrogen receptor expressing tissues, or methods of identifying cancer lesions using these compounds.

Claim (Index 1):
A radiolabeled compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X 1  is a bond, \u2014O\u2014, or \u2014C(O)\u2014; X 2  is a bond, \u2014O\u2014, or \u2014C(O)\u2014; R 1  at each occurrence is independently C 1-4  alkyl, C 1-4 haloalkyl, halogen, \u2014CN, \u2014C(O)OR 1a , \u2014(CH\u2550CH)\u2014C(O)OR 1a , \u2014OR 1a , \u2014NR 1b ,R 1c , or \u2014SO 2 CH 3 , R 2  at each occurrence is independently C 1-4  alkyl, halogen, \u2014OR 2a , or deuterium; R 3  is hydrogen or C 1-4  alkyl; R 1a , R 2a  at each occurrence are independently hydrogen, C 1-4  alkyl, or C 1-4 alkylene-G 1 ; R 1b , R 1c  at each occurrence are independently hydrogen or C 1-4  alkyl; G 1  is phenyl, a 5- or 6-membered heteroaryl, or a 5- or 6-membered heterocycle, wherein the phenyl, heteroaryl, and heterocyle are each optionally substituted with 1, 2, 3, 4, or 5 substituents independently selected from the group consisting of C 1-4 alkyl, C 1-4 haloalkyl, \u2014OC 1-4 alkyl, \u2014C(O)\u2014C 1-4 alkyl, and halogen; n is 0, 1, 2, 3, 4, or 5; and p is 0, 1, 2, 3, or 4.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 99.0
- Lexical Diversity: 1.19231
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16169812', '16221201', '14649702', '15764988', '15531245']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7697368156214915
- 35 USC 102 Novelty (BERT): 0.5061402860751885
- Combined Prediction Score: 0.7433771626668613
- Mean Citation Score: 244.466104
- Max Citation Score: 257.54813
- Similarity Product: 170.10576310486798

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test