PATENT CLAIM ANALYSIS

Application Number: 16089227
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-04
Patent Classification: ["435", "007100"]

Abstract:
The present invention relates to methods for detecting, diagnosing and/or treating ulcerative interstitial cystitis (UIC) by detecting in a urine sample from a patient the levels of each of the proteins IL-6, IL-8 and GRO [also known as CXCL 1 (chemokine C-X-C motif ligand 1]. In some embodiments, the method also includes diagnosing the patient with UIC when each of the proteins IL-6, IL-8 and GRO in the urine sample is at a different level than a statistically validated threshold for the respective proteins. In some embodiments a companion diagnostic, e.g., a cystoscopy, is used in conjunction with the protein biomarker diagnostic. In some embodiments, once UIC is diagnosed, the patient is treated for the UIC.

Claim (Index 44):
The method of  claim 42 , wherein the patient is diagnosed with UIC when the levels of each of the proteins IL-6, IL-8, and GRO in the urine sample are at a level at least 1.5 times greater than a statistically validated threshold for each of the respective proteins.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 97.0
- Lexical Diversity: 1.83562
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14849386', '14175476', '11354609', '13388613', '13498411']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6163208444829505
- 35 USC 102 Novelty (BERT): 0.5064454098114874
- Combined Prediction Score: 0.6053333010158043
- Mean Citation Score: 210.92163600000003
- Max Citation Score: 224.33083
- Similarity Product: 131.68466028453707

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test