PATENT CLAIM ANALYSIS

Application Number: 15921596
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "021900"]

Abstract:
Pyrrolidine carboxamido derivatives, optical isomers thereof, and salts thereof that are able to prevent, improve, and/or treat inflammatory conditions, including inflammatory bowel disease, and methods for preparing and using the same are provided.

Claim (Index 5):
A method for preventing, improving, or treating disease or syndrome, which comprises administering to a subject in need a composition containing, as an active component, a compound represented by the following Formula 1, an optical isomer thereof, or a salt thereof, wherein the disease or syndrome involves formation of a Pellino-1 induced inflammatory signal transduction complex containing MyD88, RIP1, or both: wherein: n is 0, 1, or 2; A is -a1-, which is an amino acid independently selected from the group consisting of alanine, (Ala, A), arginine (Arg, R), asparagine (Asn, N), aspartic acid (Asp, D), cysteine (Cys, C), glutamic acid (Glu, E), glutamine (Gln, Q), glycine (Gly, G), histidine (His, H), isoleucine (Ile, I), leucine (Leu, L), lysine (Lys, K), methionine (Met, M), phenylalanine (Phe, F), proline (Pro, P), serine (Ser, S), threonine (Thr, T), tryptophan (Trp, W), tyrosine (Tyr, Y), and valine (Val, V), both terminal ends of the amino acid being coupled to a carbonyl group or an amine group by an amide bond; and R1 is a straight chain or branched chain C1-36 alkyl, a straight chain or branched chain C2-36 alkenyl including at least one double bond, or a straight chain or branched chain C2-36 alkynyl including at least one triple bond (SEQ ID NO: 1).

Metadata:
- Claim Count in Document: 43.0
- Percentile: 90.0
- Lexical Diversity: 1.33333
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11122989', '12786221', '15497822', '11482855', '14649902']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7846127530627849
- 35 USC 102 Novelty (BERT): 0.4968602993930582
- Combined Prediction Score: 0.7558375076958123
- Mean Citation Score: 197.153088
- Max Citation Score: 204.18689
- Similarity Product: 130.74260112003444

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test