PATENT CLAIM ANALYSIS

Application Number: 16061597
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "362000"]

Abstract:
Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Claim (Index 14):
The compound of  claim 1  selected from:\n tert-butyl (Z)-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)carbamate, \n (Z)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethan-1-aminium chloride, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-(sulfamoylamino)ethyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032,4-dihydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-4-ethoxy-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-2-((4-(N-(3-Bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)oxy)ethan-1-aminium chloride, \n diethyl (Z)-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)phosphonate, \n (Z)-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)phosphonic acid, \n (Z)-N-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)acetamide, \n ethyl (Z)-3-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)propanoate, \n (Z)-3-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)propanoic acid, \n (Z)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)acetic acid, \n (Z)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)propanoic acid, \n (Z)-N-(3-bromo-4-fluorophenyl)-4-((2,3-dihydroxypropyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-hydroxypropyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((3-hydroxypropyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((4-hydroxybutyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n methyl (Z)-1-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)cyclobutane-1-carboxylate, \n methyl (Z)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)acetate, \n (Z)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(propylthio)-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-N-(3-bromo-4-fluorophenyl)-4-(ethylthio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-4-((azetidin-3-ylmethyl)thio)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-4-(azetidin-3-ylthio)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (Z)-(((2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate, \n (Z)-(((2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate), \n (Z)-N-(2-((4-(N-(3-Bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)acetamide, \n methyl(Z)-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-thiadiazol-3-yl)thio)ethyl)carbamate, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(1-hydroxy-2-methylpropan-2-yl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2-hydroxy-2-methylpropyl)acetamide, \n (R)-N-(3-bromo-4-fluorophenyl)-4-((2,3-dihydroxy-3-methylbutyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (S)-N-(3-bromo-4-fluorophenyl)-4-((2,3-dihydroxy-3-methylbutyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-((N-(2-methoxyethyl) sulfamoyl)-ethyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n (R)-N-(3-chloro-4-fluorophenyl)-4-(((1,1-dioxido-1,2,5-thiadiazolidin-3-yl)methyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (R)-N-(3-bromo-4-fluorophenyl)-4-(((1,1-dioxido-1,2,5-thiadiazolidin-3-yl)methyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n (3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(((6-oxo-1,6-dihydropyridazin-3-yl)methyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-((2-(methylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)ethyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n N-(2-((4-(N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)acetamide, \n (R)-N-(3-cyano-4-fluorophenyl)-4-((2,3-dihydroxy-3-methylbutyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (S)-N-(3-cyano-4-fluorophenyl)-4-((2,3-dihydroxy-3-methylbutyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(2-((4-(N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)cyclopropanecarboxamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-methylacetamide, \n (R)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2,3-dihydroxypropyl)acetamide, \n (R)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(((3-methyl-2-oxoimidazolidin-4-yl)methyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n Dimethyl 2,2\u2032-(((2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)ethyl)phosphoryl)bis(azanediyl))(Z)-diacetate, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-(3-methylureido)ethyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-Bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-ureidoethyl)thio)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-((2-(sulfamoylamino)ethyl) thio)-1,2,5-thiadiazole-3-carboximidamide, \n methyl S-{4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}-L-cysteinate, \n N-{2-[(4-{N-[4-fluoro-3-(trifluoromethyl)phenyl]-N\u2032-hydroxycarbamimidoyl}-1,2,5-oxadiazol-3-yl)sulfanyl]ethyl}acetamide, \n N-[4-fluoro-3-(trifluoromethyl)phenyl]-N\u2032-hydroxy-4-[(2-hydroxyethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-[2-({4-[N-(4-fluoro-3-methylphenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]acetamide, \n N-{2-[(4-{N-[4-fluoro-3-(trifluoromethoxy)phenyl]-N\u2032-hydroxycarbamimidoyl}-1,2,5-oxadiazol-3-yl)sulfanyl]ethyl}acetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(6-hydroxyhexyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(3-hydroxy-4-methylpentyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-[(2-{[2-(ethylamino)-3,4-dioxocyclobut-1-en-1-yl]amino}ethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-[(2-carbamimidamidoethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n S-{4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}homocysteine, \n N-[2-({4-[N-(5-bromo-2,4-difluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]acetamide, \n N-[2-({4-[N-(3-bromophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]acetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-phenylacetamide, \n N-[2-({4-[N-(4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]acetamide, \n N-(3-bromo-4-fluorophenyl)-4-[(2,3-dihydroxypropyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-[2-({4-[N-(3-ethylphenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]acetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(pyrrolidin-3-ylsulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-[(cyanomethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[(1-cyanocyclopropyl)methyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 1-[({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)methyl]-N-methylcyclopropanecarboxamide, \n 3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-methylpropanamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(4-sulfamoylphenyl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(piperidin-4-ylsulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n 4-({2-[(2-amino-3,4-dioxocyclobut-1-en-1-yl)amino]ethyl}sulfanyl)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-hydroxy-2-phenylethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-({2-[(2,3-dihydroxypropyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(1-sulfamoylpiperidin-4-yl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)acetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(4-methylmorpholin-2-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-[2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]-2,2,2-trifluoroacetamide, \n N-(3-bromo-4-fluorophenyl)-4-{[(3-cyanobicyclo[1.1.1]pent-1-yl)methyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-methylazetidine-1-carboxamide, \n N-(3-bromo-4-fluorophenyl)-4-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[(2R)-5-oxopyrrolidin-2-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[(2S)-5-oxopyrrolidin-2-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-(N\u2033-cyanocarbamimidamido)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(6-oxo-1,6-dihydropyridin-2-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n 4-[(1-acetylpiperidin-4-yl)sulfanyl]-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[6-oxo-4-(trifluoromethyl)-1,6-dihydropyridin-2-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-({2-[(cyclopropylmethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-({2-[(2-hydroxyethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({2-[(2-morpholin-4-yl-3,4-dioxocyclobut-1-en-1-yl)amino]ethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-({2-[(3,4-dioxo-2-piperidin-1-ylcyclobut-1-en-1-yl)amino]ethyl}sulfanyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-({2-[(1-methylethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-({3,4-dioxo-2-[(pyridin-4-ylmethyl)amino]cyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)propanamide, \n 1-methylethyl (2S,6S)-4-[2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]-2,6,9-trimethyl-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate 4-oxide (non-preferred name), \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n 4-[(2-{[(E)-1-amino-2-nitroethenyl]amino}ethyl)sulfanyl]-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 4-[(2-{bis[(2-methoxyethyl)amino]phosphoryl}ethyl)sulfanyl]-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n diphenyl [2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]phosphonate, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(4-methyl-6-oxo-1,6-dihydropyridin-2-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n 4-({2-[bis(methylamino)phosphoryl]ethyl}sulfanyl)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 4-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-methylpiperidine-1-carboxamide, \n ethyl N-[{[2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]amino}(ethyl)phosphoryl]glycinate, \n 3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-(2-methoxyethyl)propanamide, \n 3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-(2-hydroxyethyl)propanamide, \n bis({[(1-methylethoxy)carbonyl]oxy}methyl) [3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)propyl]phosphonate, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-ethylacetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N,N-dimethylacetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-(2-hydroxyethyl)acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-cyclopropylacetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-cyclobutylacetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-oxopropyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n 4-({2-[bis(benzylamino)phosphoryl]ethyl}sulfanyl)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 4-({[bis(methylamino)phosphoryl]methyl}sulfanyl)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n phenyl hydrogen [3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)propyl]phosphonate, \n ethyl N-{[3-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)propyl](phenoxy)phosphoryl}glycinate, \n methyl 6-[({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)methyl]-3-oxo-2-oxa-5,7-diaza-6-phosphanonan-9-oate 6-oxide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[(4S)-3-methyl-2-oxoimidazolidin-4-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[(4S)-1-methyl-2-oxoimidazolidin-4-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({[(4R)-1-methyl-2-oxoimidazolidin-4-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(2-oxo-1,3-oxazolidin-5-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n 4-{[(2R)-2-amino-3-hydroxypropyl]sulfanyl}-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-morpholin-4-ylethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-({2-[(butylcarbamoyl)amino]ethyl}sulfanyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n ethyl {[2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]carbamoyl}carbamate, \n N-(3-bromo-4-fluorophenyl)-4-({2-[(cyclopentylcarbamoyl)amino]ethyl}sulfanyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-{[(tetrahydro-2H-pyran-4-ylmethyl)carbamoyl]amino}ethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-[(2-{[(furan-2-ylmethyl)carbamoyl]amino}ethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-{[(2-methoxyethyl)carbamoyl]amino}ethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-chloro-4-fluorophenyl)-N\u2032-hydroxy-4-{[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-(2-fluoroethyl)acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-(2-hydroxypropyl)acetamide, \n 4-({2-[bis(dimethylamino)phosphoryl]ethyl}sulfanyl)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-4-{[(2S)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-{2-[(4-{N-[3-(difluoromethyl)-4-fluorophenyl]-N\u2032-hydroxycarbamimidoyl}-1,2,5-oxadiazol-3-yl)sulfanyl]ethyl}acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[(1s,3R,4S)-3,4-dihydroxycyclopentyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]acetamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-({[(4S)-3-methyl-2-oxoimidazolidin-4-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-4-{[(2R)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-({[(2R)-5-oxopyrrolidin-2-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-({[(2S)-5-oxopyrrolidin-2-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-({[(4R)-3-methyl-2-oxoimidazolidin-4-yl]methyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(2-methyl-1H-imidazol-1-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(1,3-thiazol-4-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(1-methyl-1H-imidazol-2-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(1H-1,2,4-triazol-1-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(1,2,4-oxadiazol-3-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(1,3-thiazol-2-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(piperidin-3-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(1H-imidazol-4-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-[(2-fluoroethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-(but-2-yn-1-ylsulfanyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(tetrahydro-2H-pyran-4-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-piperazin-1-ylethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(4-methylpiperazin-1-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n 4-{[(2R)-2,3-dihydroxypropyl]sulfanyl}-N-[4-fluoro-3-(trifluoromethyl)phenyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n 4-{[(2S)-2,3-dihydroxypropyl]sulfanyl}-N-[4-fluoro-3-(trifluoromethyl)phenyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-[3-(difluoromethyl)-4-fluorophenyl]-4-{[(2S)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-[3-(difluoromethyl)-4-fluorophenyl]-4-{[(2R)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-chloro-4-fluorophenyl)-4-{[(2R)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-chloro-4-fluorophenyl)-4-{[(2S)-2,3-dihydroxypropyl]sulfanyl}-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-({2-[(methylsulfonyl)amino]ethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(1H-imidazol-1-yl)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-[(1R)-2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-1-(hydroxymethyl)ethyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[2-hydroxy-1-(hydroxymethyl)-1-methylethyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[(2S)-2,3-dihydroxypropyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[2-hydroxy-1-(hydroxymethyl)propyl]acetamide, \n 2-({4-[N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-[(1r,3R,4S)-3,4-dihydroxycyclopentyl]acetamide, \n N-(3-cyano-4-fluorophenyl)-4-({2-[(cyclopropylsulfonyl)amino]ethyl}sulfanyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-[(1R)-2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-1-methylethyl]acetamide, \n N-[(1S)-2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-1-methylethyl]acetamide, \n N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxy-4-{[2-(sulfamoylamino)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-[2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]-2-hydroxyacetamide, \n N-[3-(difluoromethyl)-4-fluorophenyl]-N\u2032-hydroxy-4-({2-[(methylsulfonyl)amino]ethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-chloro-4-fluorophenyl)-N\u2032-hydroxy-4-({2-[(methylsulfonyl)amino]ethyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n 2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-methylacetamide, \n 2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)-N-oxetan-3-ylacetamide, \n (1R)-N-[2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]-2,2-difluorocyclopropanecarboxamide, \n (1S)-N-[2-({4-[N-(3-cyano-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}sulfanyl)ethyl]-2,2-difluorocyclopropanecarboxamide, \n N-(3-chloro-4-fluorophenyl)-4-[(2,3-dihydroxy-3-methylbutyl)sulfanyl]-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(4H-1,2,4-triazol-3-ylmethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-({(2R)-3-hydroxy-2-[(methylsulfonyl)amino]propyl}sulfanyl)-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-[(2-morpholin-4-yl-2-oxoethyl)sulfanyl]-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-{[(2R)-3-hydroxy-2-(sulfamoylamino)propyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-((2-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-2-oxoethyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-((2-((3S,4S)-3,4-dihydroxypiperidin-1-yl)-2-oxoethyl)thio)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n (R)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(1-hydroxypropan-2-yl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-((3 S,4S)-3-hydroxytetrahydro-2H-pyran-4-yl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(N-methylsulfamoyl)acetamide, \n (S)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2-hydroxypropyl)acetamide, \n (R)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2-hydroxypropyl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(1-(hydroxymethyl)cyclopropyl)acetamide, \n (S)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2-hydroxypropyl)acetamide, \n (R)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2,3-dihydroxypropyl)-2-methylpropanamide, \n (S)-2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(1-hydroxypropan-2-yl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(2-hydroxy-3-morpholinopropyl)acetamide, \n 2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)thio)-N-(3,4-dihydroxy-2-methylbutan-2-yl)acetamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-(dimethylamino)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-thiadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-4-{[2-({2-[(cyclopropylmethyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)ethyl]sulfanyl}-N\u2032-hydroxy-1,2,5-thiadiazole-3-carboximidamide, and \n N-(3-bromo-4-fluorophenyl)-4-[(2-{[2-(cyclopropylamino)-3,4-dioxocyclobut-1-en-1-yl]amino}ethyl)sulfanyl]-N\u2032-hydroxy-1,2,5-thiadiazole-3-carboximidamide; \n N-(2-((4-(N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)oxy)ethyl)acetamide, \n 2-((4-(N-(3-Bromo-4-fluorophenyl)-N\u2032-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-yl)oxy)-N-(2-hydroxyethyl)acetamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(2-(sulfamoylamino)ethoxy)-1,2,5-oxadiazole-3-carboximidamide, \n 4-(2-aminoethoxy)-N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-1,2,5-oxadiazole-3-carboximidamide, \n N-(3-bromo-4-fluorophenyl)-N\u2032-hydroxy-4-(2-(methylsulfonamido)ethoxy)-1,2,5-oxadiazole-3-carboximidamide \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 2.25
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13780510', '11641284', '15632986', '13734263', '11430441']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8014753367305877
- 35 USC 102 Novelty (BERT): 0.5923280998916466
- Combined Prediction Score: 0.7805606130466937
- Mean Citation Score: 485.00033600000006
- Max Citation Score: 496.86115
- Similarity Product: 445.330319946155

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test