PATENT CLAIM ANALYSIS

Application Number: 16144358
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["525", "410000"]

Abstract:
The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. In one embodiment, the POZ derivative is a terminally activated monofunctional POZ derivative.

Claim (Index 5):
The terminally activated POZ compound of  claim 1 , wherein the active functional group is selected from the group consisting of: aldehyde, active carbonate (\u2014O\u2014CO\u2014Z), maleimide, sulfonate ester (OSO 2 \u2014R 23 ), hydrazide, epoxide, iodoacetamide, alkyne, azide, isocyanate, cyanate isothiocyanate, thiocyanate, nitrile, a carbonyldiimidazole derivative, vinylsulfone, carboxylic acid halide, active ester (\u2014CO\u2014Z) and carboxylic acid, wherein any of the foregoing may be substituted or unsubstituted, Z is an activating group and R 23  is an unsubstituted or substituted alkyl, alkenyl, alkynyl, aralkyl or aryl group.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.7551
- Patent Class: 525.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15453686', '12529001', '12680448', '13003306', '13367128']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7990277509342678
- 35 USC 102 Novelty (BERT): 0.5437996930917247
- Combined Prediction Score: 0.7735049451500134
- Mean Citation Score: 330.004808
- Max Citation Score: 419.58813
- Similarity Product: 383.8004518299168

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test