PATENT CLAIM ANALYSIS

Application Number: 15763564
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["435", "147000"]

Abstract:
The invention relates to an  Amycolatopsis  strain derived from the  Amycolatopsis  Zyl 926 strain having at least one additional copy of the FCS and ECH genes encoding feruloyl-CoA-synthetase and enoyl-CoA-hydratase/aldolase integrated at the integration site of the φC31 phage. The invention also relates to the method for producing such strains, the integration cassette of the FCS and ECH genes, the use of said strains in a method for producing vanillin, and a method for producing vanillin.

Claim (Index 9):
An integration cassette characterized in that it comprises:\n i. an expression cassette of the FCS gene encoding feruloyl-coA-synthetase having the sequence SEQ ID NO: 1 or any sequence at least 80%, preferably at least 90%, and more preferably at least 95% identical to SEQ ID NO: 1 and ECH encoding enoyl-coA-hydratase/aldolase having the sequence SEQ ID NO: 2 or any sequence at least 80%, preferably at least 90%, and more preferably at least 95% identical to SEQ ID NO: 2; ii. means for integration of the cassette into the genome of the strain  Amycolatopsis  Zyl926, comprising the int gene of the \u03c6C31 phage having the sequence SEQ ID NO: 3 or any sequence at least 80%, preferably at least 90%, and more preferably at least 95% identical to the sequence SEQ ID NO: 3 and the attP attachment site of the \u03c6C31 phage having the sequence SEQ ID NO: 4; iii. means for selecting transformed  Escherichia coli  ET12567 strains comprising neomycin and a beta-lactam; iv. means for selecting  Amycolatopsis  Zyl926 strains having integrated said integration cassette comprising a marker for resistance to apramycin.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 90.0
- Lexical Diversity: 1.8
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14906429', '13985261', '15879341', '15322745', '14409227']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6278957399545537
- 35 USC 102 Novelty (BERT): 0.5342784108550832
- Combined Prediction Score: 0.6185340070446067
- Mean Citation Score: 331.533256
- Max Citation Score: 386.32785
- Similarity Product: 275.69335546010427

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test