PATENT CLAIM ANALYSIS

Application Number: 15870306
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "04400A"]

Abstract:
Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.

Claim (Index 11):
The method of  claim 1 , wherein the modified oligonucleotide comprises:\n a) a gap segment consisting of linked deoxynucleosides; b) a 5\u2032 wing segment consisting of linked nucleosides; c) a 3\u2032 wing segment consisting of linked nucleosides; wherein the gap segment is positioned between the 5\u2032 wing segment and the 3\u2032 wing segment and wherein each nucleoside of each wing segment comprises a modified sugar.

Metadata:
- Claim Count in Document: 61.0
- Percentile: 86.0
- Lexical Diversity: 1.86047
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14149715', '13520997', '14959714', '14701999', '14552436']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.835356389421029
- 35 USC 102 Novelty (BERT): 0.6060904153572089
- Combined Prediction Score: 0.8124297920146469
- Mean Citation Score: 453.858652
- Max Citation Score: 537.817
- Similarity Product: 506.3065291036368

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test