PATENT CLAIM ANALYSIS

Application Number: 15757269
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["424", "450000"]

Abstract:
The present disclosure is directed to methods of producing monosized protocells from monosized mesoporous silica nanoparticles (mMSNPs) and their use for targeted drug delivery formulations and systems and for biomedical applications. The present disclosure is also directed in part to a multilamellar or unilamellar protocell vaccine to deliver full length viral protein and/or plasmid encoded viral protein to antigen presenting cells (APCs) in order to induce an immunogenic response to a virus.

Claim (Index 18):
A method to prepare a population of protocells comprising a population of nanoparticles surrounded by a lipid bi-layer, comprising: agitating said nanoparticles with liposomes in solution; and separating said nanoparticles from said solution, wherein said liposomes are present in said solution at a weight ratio of at least twice that of said nanoparticles, said population of protocells exhibits a polydispersity index of less than about 0.2.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 1.36842
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14113371', '13143164', '12909572', '15320903', '14354706']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7304751529189807
- 35 USC 102 Novelty (BERT): 0.5619214280230148
- Combined Prediction Score: 0.7136197804293841
- Mean Citation Score: 348.0356040000001
- Max Citation Score: 464.6732
- Similarity Product: 349.3828293950557

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test