PATENT CLAIM ANALYSIS

Application Number: 15893480
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["424", "158100"]

Abstract:
The present invention provides compositions and methods which involve specifically antagonizing GDF8 and Activin A. In certain embodiments, compositions are provided which comprise a GDF8-specific binding protein and an Activin A-specific binding protein. For example, the invention includes compositions comprising an anti-GDF8 antibody and an anti-Activin A antibody. In other embodiments, antigen-binding molecules are provided which comprise a GDF8-specific binding domain and an Activin A-specific binding domain. For example, the invention includes bispecific antibodies that bind GDF8 and Activin A. The compositions of the present invention are useful for the treatment of diseases and conditions characterized by reduced muscle mass or strength, as well as other conditions which are treatable by antagonizing GDF8 and/or Activin A activity.

Claim (Index 30):
The method of  claim 28 , wherein the anti-GDF8 antibody or antigen-binding fragment thereof comprises three HCDRs comprising SEQ ID NO:10, SEQ ID NO:11, and SEQ ID NO:12, and three LCDRs comprising SEQ ID NO:14, SEQ ID NO:15, and SEQ ID NO:16.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 2.06452
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13676233', '14447444', '15637867', '13115170', '14462085']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7910412527256849
- 35 USC 102 Novelty (BERT): 0.6334914249592115
- Combined Prediction Score: 0.7752862699490376
- Mean Citation Score: 490.107436
- Max Citation Score: 632.52136
- Similarity Product: 556.1119764047576

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test