PATENT CLAIM ANALYSIS

Application Number: 16241954
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["424", "400000"]

Abstract:
Described herein are polymeric drug-carrying nanogels that are capable of targeting to P-selectin for the treatment of cancer and other diseases and conditions associated with P-selectin. Furthermore, in certain embodiments, the nanogels presented here offer a drug release mechanism based on acidic pH in the microenvironment of a tumor, thereby providing improved treatment targeting capability and allowing use of lower drug doses, thereby reducing toxicity.

Claim (Index 1):
A polymeric nanoparticle with affinity to P-selectin, the nanoparticle comprising a non-covalent assembly of\n a sulfated polymer species comprising free hydroxyl moieties and free sulfate moieties capable of targeting P-selectin, the sulfated polymer species comprising one or more of a sulfated polysaccharide, a protein, or a fucoidan; a hydrophobic drug; and a dye comprising a fluorophore; wherein\n the nanoparticle has an intensity-weighted average diameter as determined by dynamic light scattering of about 20 nm and about 200 nm; and \n the non-covalent assembly is a self-assembly of the sulfated polymer species around the hydrophobic drug.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 99.0
- Lexical Diversity: 1.39216
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15069311', '14526660', '15470169', '15752008', '12997983']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.603237792189693
- 35 USC 102 Novelty (BERT): 0.6402136441569799
- Combined Prediction Score: 0.6069353773864217
- Mean Citation Score: 296.038546
- Max Citation Score: 614.23975
- Similarity Product: 546.5203324672282

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test