PATENT CLAIM ANALYSIS

Application Number: 15755481
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "04400A"]

Abstract:
The present invention relates to novel isolated nucleic acid molecules (novel miRNAs and novel miRNA precursor molecules) as well as vectors, host cells, primers, cDNA-transcripts, polynucleotides derived from said isolated nucleic acid molecules and their use in diagnosis and therapy. Furthermore the present invention relates to methods and kits for diagnosing a disease, such as Multiple Sclerosis (MS) or Alzheimer's Disease (AD) employing said novel isolated nucleic acid molecules (novel miRNAs molecules).

Claim (Index 16):
A kit for diagnosing and/or prognosing a disease, comprising:\n (a) means for determining an expression profile of at least one isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 1, SEQ ID NO: 3 to SEQ ID NO: 37, a fragment thereof, and a nucleotide sequence with at least 90%, 94%, 96% or greater sequence identity thereto, or of a complement thereof, which comprise\n (i) one or more polynucleotides for detecting the isolated nucleic acid molecule or the complement thereof, and \n (ii) a biochip, a RT-PCT system, a PCR-system, a flow cytometer, a Luminex system or a next generation sequencing system. and \n (b) one or more reference expression profiles, wherein the expression profile in (a) and the reference expression profiles in (b) are determined from the same at least one nucleic acid molecule in the same type of blood sample.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 88.0
- Lexical Diversity: 1.69231
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14383518', '14873385', '13376225', '14442439', '11747409']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7905389493562867
- 35 USC 102 Novelty (BERT): 0.5368913955446646
- Combined Prediction Score: 0.7651741939751244
- Mean Citation Score: 349.89538000000016
- Max Citation Score: 386.3022
- Similarity Product: 253.1311988910556

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test