PATENT CLAIM ANALYSIS

Application Number: 16061365
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "230800"]

Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments, in particular for treating cardiovascular disorders.

Claim (Index 8):
The compound according to  claim 4  or a stereoisomer, an enantiomer, a diastereomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein:\n R 1  is independently selected from F, Cl, Br, OH, OC 1-4  alkyl, OC 3-6 cycloalkyl, CN, C 1-4  alkyl, and C 3-6 cycloalkyl; \n R 2  is independently selected from \u2014CH 2 CH 2 CH 2 CH 3 , \u2014CH 2 CH 2 CH(CH 3 ) 2 , CH 2 CH 2 CH 2 CF 3 , \u2014CH 2 -cyclopropyl, \u2014CH 2 CH 2 -cyclopropyl, CH 2 CH 2 CH\u2550CH 2 , phenyl (optionally substituted with F), pyridyl (optionally substituted with C 1-2 alkyl), C 3-5  cycloalkyl, CH 2 O(CH 2 ) 1-3 CH 3 , CH 2 OCH(CH 3 ) 2 , and CH 2 O-cyclopropyl; \n R 3  is independently selected from\n (1) \u2014(CR 4 R 4 ) r NR 8 R 8  and \n (2) \u2014(CR 4 R 4 ) r C(\u2550O)NR 8 R 8 ; \n \n R 4  is independently selected from H, F, Cl, N(CH 3 ) 2 , OCH 3 , and CH 3 ; or R 4  and R 4  together with the carbon atom to which they are both attached form C 3-6  cycloalkyl substituted with 0-5 R e ; \n R 6  is independently selected from H, F, Cl, Br, \u2014OCH 3 , \u2014OCF 3 , O, CN, CH 3 , CF 3 \u2014(CH 2 ) n -aryl, \u2014(CH 2 ) n \u2014C 3-6  cycloalkyl substituted with 0-3 R e , and \u2014(CH 2 ) n -heterocyclyl substituted with 0-3 R e ; \n R 6a  is independently selected from H, CH 3 , aryl substituted with 0-3 R e , and heterocyclyl substituted with 0-3 R e ; \n R 8  and R 8  together with the nitrogen atom to which they are both attached form a heterocyclic ring selected from \n R e , at each occurrence, is independently selected from C 1-6  alkyl (optionally substituted with F and Cl), OH, OCH 3 , OCF 3 , \u2014(CH 2 ) n \u2014C 3-6  cycloalkyl, \u2014(CH 2 ) n \u2014C 4-6  heterocyclyl, \u2014(CH 2 ) n -aryl, \u2014(CH 2 ) n -heteroaryl, F, Cl, Br, CN, NO 2 , \u2550O, CO 2 H; r is independently selected from 1 and 2; and n is independently selected from zero, 1, 2, and 3.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 94.0
- Lexical Diversity: 1.19512
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16309161', '15171276', '15468230', '15767364', '16340172']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7950961613920289
- 35 USC 102 Novelty (BERT): 0.5633241935344862
- Combined Prediction Score: 0.7719189646062746
- Mean Citation Score: 396.694724
- Max Citation Score: 423.19574000000006
- Similarity Product: 378.5334620355845

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test