PATENT CLAIM ANALYSIS

Application Number: 15777147
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["435", "006100"]

Abstract:
Various embodiments include methods of diagnosing susceptibility to epilepsy in an individual or methods of managing treatment of a neurological condition in an individual, comprising: obtaining a sample from the individual; assaying the sample to determine the presence or absence of one or more biomarkers of epilepsy; and diagnosing susceptibility to epilepsy in the individual based on the presence of one or more biomarkers of epilepsy. Various embodiments further include kits for diagnostic use, comprising a diagnostic panel of one or more of the biomarkers: Let-7d-5p, miR-340-3p, miR-484, miR-151, miR-350, miR-770-5p, miR-139-3p, miR-2985, miR-101a-5p, miR-206-3p, miR-760-3p, miR-383-5p, miR-294, and miR-328a-5p.

Claim (Index 1):
A method of diagnosing susceptibility to epilepsy in an individual, comprising:\n obtaining a sample from the individual; assaying the sample to determine the presence or absence of one or more biomarkers of epilepsy; and diagnosing susceptibility to epilepsy in the individual based on the presence of one or more biomarkers of epilepsy, wherein assaying the sample comprises (i) contacting the sample with oligonucleotide probes, wherein the oligonucleotide probes specifically hybridize to the polynucleotides of SEQ. ID. NOs. 1-15 in the sample, and wherein the oligonucleotides are labeled with at least one fluorescent dye; (ii) detecting the fluorescent signals from the hybridization complex formed by the oligonucleotide probes and the polynucleotides in the sample; and (iii) detecting the presence of one or more biomarkers of epilepsy based upon the detected fluorescent signals.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 93.0
- Lexical Diversity: 2.12281
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15852128', '15125714', '15243604', '14873385', '13735760']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.3967456536059919
- 35 USC 102 Novelty (BERT): 0.5124023088006929
- Combined Prediction Score: 0.408311319125462
- Mean Citation Score: 273.42167800000004
- Max Citation Score: 280.81384
- Similarity Product: 185.15628973643305

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test