PATENT CLAIM ANALYSIS

Application Number: 15743988
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["435", "091300"]

Abstract:
The present invention is concerned with a method of producing a target RNA using a circular DNA, wherein said method does not comprise a step of linearizing said circular DNA. The present invention further relates to a circular DNA comprising an RNA polymerase promoter sequence, followed by a sequence encoding a target RNA, followed by a sequence encoding a self-cleaving ribozyme, followed by an RNA polymerase terminator sequence element, wherein the latter element may comprise several RNA polymerase terminator sequences. Multimeric DNA obtained by rolling circle amplification of said circular DNA is also within the scope of the present invention.

Claim (Index 1):
A method of producing a linear target RNA comprising the steps of:\n a) providing a circular DNA as template DNA comprising the following sequence elements from 5\u2032 to 3\u2032:\n i. an RNA polymerase promoter sequence operably linked to \n ii. a sequence encoding said target RNA operably linked to \n iii. a sequence encoding a self-cleaving ribozyme, wherein said self-cleaving ribozyme cleaves close to or at its 5\u2032 end, operably linked to \n iv. an RNA polymerase terminator sequence element; and \n b) in vitro transcription of said template DNA to obtain said target RNA; c) purifying said target RNA by at least one purification step in order to obtain purified target RNA; wherein said method does not comprise a step of linearizing said circular DNA provided in step a).

Metadata:
- Claim Count in Document: 51.0
- Percentile: 86.0
- Lexical Diversity: 2.07692
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11523884', '09997931', '10855975', '15503383', '10600581']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6265639083288552
- 35 USC 102 Novelty (BERT): 0.5197012870151222
- Combined Prediction Score: 0.6158776461974819
- Mean Citation Score: 315.14471999999995
- Max Citation Score: 341.07898
- Similarity Product: 265.5025272401428

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test