PATENT CLAIM ANALYSIS

Application Number: 16203108
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-09
Patent Classification: ["514", "081000"]

Abstract:
The present disclosure provides prodrugs of biologically active 2,4-pyrimidinediamine compounds, compositions comprising the prodrugs, intermediates and methods for synthesizing the prodrugs and methods of using the prodrugs in a variety of applications.

Claim (Index 15):
The method of  claim 14  in which R P  is selected from the group consisting of \u2014(CR d R d )\u2014O\u2014P(O)(OR e )(OH), \u2014(CR d R d )\u2014O\u2014P(OR e )(OR e ), and salts thereof, wherein each R e  is, independently of the others, selected from the group consisting of substituted or unsubstituted lower alkyl, substituted or unsubstituted (C 6 -C 14 ) aryl, substituted or unsubstituted (C 7 -C 20 ) arylalkyl, \u2014(CR d R d ) y \u2014OR f , \u2014(CR d R d ) y \u2014O\u2014C(O)R f , \u2014(CR d R d ) y \u2014O\u2014C(O)OR f , \u2014(CR d R d ) y \u2014S\u2014C(O)R f , \u2014(CR d R d ) y \u2014S\u2014C(O)OR f , \u2014(CR d R d ) y \u2014NH\u2014C(O)R, \u2014(CR d R d ) y \u2014NH\u2014C(O)OR f  and \u2014Si(R d ) 3 , wherein each R f  is, independently of the others, selected from the group consisting of unsubstituted or substituted lower alkyl, substituted or unsubstituted (C 6 -C 14 ) aryl, and substituted or unsubstituted (C 7 -C 20 ) arylalkyl; each R g  is, independently of the others, selected from the group consisting of hydrogen and lower alkyl; each R h  is, independently of the others, selected from the group consisting of hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower cycloheteroalkyl, substituted or unsubstituted (C 6 -C 14 ) aryl, substituted or unsubstituted (C 7 -C 20 ) arylalkyl and substituted or unsubstituted 5-14 membered heteroaryl; y is an integer ranging from 1 to 3; z is an integer ranging from 0 to 2; and each R d  is independently of the others, selected from the group consisting of hydrogen, optionally substituted lower alkyl, optionally substituted (C 6 -C 14 ) aryl and optionally substituted (C 7 -C 20 ) arylalkyl; where the optional substituents are, independently of one another, selected from hydroxyl, lower alkoxy, (C 6 -C 14 ) aryloxy, lower alkoxyalkyl, and halogen, or, alternatively, two R d  bonded to the same carbon atom are taken together with the carbon atom to which they are bonded to form a cycloalkyl group containing from 3 to 8 carbon atoms.

Metadata:
- Claim Count in Document: 62.0
- Percentile: 98.0
- Lexical Diversity: 1.4
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14310312', '14995027', '12268218', '11453731', '13909858']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8622680081230618
- 35 USC 102 Novelty (BERT): 0.6245344529033273
- Combined Prediction Score: 0.8384946526010884
- Mean Citation Score: 551.374864
- Max Citation Score: 559.08997
- Similarity Product: 548.5998616604305

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test