PATENT CLAIM ANALYSIS

Application Number: 15863759
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["128", "831000"]

Abstract:
Described are methods for reversible occlusion of a body lumen by way of degradation as a result of exposure to one or more stimuli such as light. The methods include administering one or more substance(s) into a body lumen of a subject and forming a stimuli-responsive polymer mass in the body lumen from the one or more substance(s). The mass is sufficient to occlude the body lumen in a manner that prevents transport of at least one material through the body lumen and is susceptible to on-command reversal in the body lumen upon exposure to one or more stimuli. The methods include administering one or more stimuli to a polymer mass in a body lumen for a time and intensity to cause the reverse the polymer mass. The methods are particular useful for applications in which it is desirable to temporarily occlude a body lumen, such as male and female contraception.

Claim (Index 10):
The method of  claim 1 , wherein the one or more substance(s) comprise one or more photolabile moieties chosen from one or more of 2-nitrobenzyl, a-bromo-2-nitrotoluene, 2-nitrobenzyl chloride, 5-methyl-2-nitrobenzyl alcohol, 5-hydroxy-2-nitrobenzyl alcohol, 4,5-dimethoxy-2-nitrobenzyl alcohol, 4,5-dimethoxy-2-nitrobenzyl chloroformate, 4,5-dimethoxy-2-nitrobenzyl bromide, 5-chloro-2-nitrobenzyl alcohol, 5-methyl-2-nitrobenzyl chloride, 4-chloro-2-nitrobenzyl alcohol, 2-nitrobenzyl alcohol, 4-chloro-2-nitrobenzyl chloride, 4-fluoro-2nitrobenzyl bromide, 5-fluoro-2-nitrobenzyl alcohol, and 2-methyl-3-nitrobenzyl alcohol, 2-hydroxy-5-nitrobenzyl alcohol, 2-hydroxy-5-nitrobenzyl bromide, 2-methoxy-5-nitrobenzyl bromide, 2-chloro-5-nitrobenzyl alcohol, 2-fluoro-5-nitrobenzyl alcohol, 2-methyl-3-nitrobenzyl chloride, and 2-acetoxy-5-nitrobenzyl chloride, 4-[4-(1-hydroxyethyl)-2-methoxy-5-nitrophenoxy]butanoic acid, \u03b1-carboxy-2-nitrobenzyl (CNB), 1-(2-nitrophenyl)ethyl (NPE), 4,5-dimethoxy-2-nitrobenzyl (DMNB), 1-(4,5-dimethoxy-2-nitrophenyl)ethyl (DMNPE), 5-carboxymethoxy-2-nitrobenzyl (CMNB), nitrophenyl (NP), or any of their derivatives, or the photolabile moiety is derived from one or more of benzoin, phenacyl, coumaryl, arylmethyl, thiopixyl, or arylsulfonamides, a 1-o-phenylethyl ester, 1-o-nitrophenylethyl, or any of their derivatives, a 1-o-phenylethyl ester with an order of magnitude faster degradation than o-nitrobenzyl ester, or the photolabile moiety is O-o-Nitrobenzyl O\u2032, O\u2033-diethyl phosphate.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 2.29577
- Patent Class: 128.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15349824', '15021167', '10461853', '13910730', '11962077']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6097869983975287
- 35 USC 102 Novelty (BERT): 0.5046291229479656
- Combined Prediction Score: 0.5992712108525724
- Mean Citation Score: 172.66341599999996
- Max Citation Score: 284.22467
- Similarity Product: 186.7812829147035

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test