PATENT CLAIM ANALYSIS

Application Number: 15762488
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "186000"]

Abstract:
The present invention relates to highly efficient Nrf2 activators-CO-releasing molecules of formula (I) and (II) capable of increasing HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases, wherein CORM represents a carbonyl metal complex chosen from among: Mn(CO) 5 , formula (III), (IV), (V), (VI), (VII), (VIII) and (IX).

Claim (Index 8):
The compound according to any to  claim 3  of following general formula (IIa): wherein R 17  to R 20  represent independently: H, halogen, \u2014CN, \u2014NO 2 , \u2014NO, \u2014CHO, \u2014NR x R y , \u2014NR x R y R z +, \u2014SO 3 H, \u2014CO 2 R x , \u2014SO 2 R x , \u2014SO 2 NR x R y , \u2014OH, \u2014OR x , \u2014COR y , \u2014SR x , \u2014CONR x R y , \u2014SO 2 (O)R x , a group selected from saturated (C 1 -C 6 )alkyl or unsaturated (C 1 -C 6 )alkyl, where R x  R y  and R z  represent independently H or (C 1 -C 6 )alkyl, or two consecutive radicals selected from R 17  to R 20 , taken together, form a bridging group selected from the group consisting of \u2014(CH 2 ) m \u2014, or \u2014O\u2014(CH 2 ) o \u2014O\u2014, m being an integer between 3 and 5 and o being 1 or 2.

Metadata:
- Claim Count in Document: 48.0
- Percentile: 90.0
- Lexical Diversity: 1.63333
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15127674', '13940641', '12922122', '15510427', '12604970']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7963933620406426
- 35 USC 102 Novelty (BERT): 0.5947304848975974
- Combined Prediction Score: 0.7762270743263381
- Mean Citation Score: 389.86244
- Max Citation Score: 584.03534
- Similarity Product: 402.7569963251937

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test