PATENT CLAIM ANALYSIS

Application Number: 15765933
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["530", "315000"]

Abstract:
The present invention relates to new solid phase peptide methods for synthesizing analogues that exhibit oxytocin antagonist activity, specifically Barusiban and its intermediates. Specifically, the present invention relates to a solid phase process for preparing a compound having the formula c[AA 1 -AA 6 ]-AA 7 -ol, wherein AA 1  is propionic acid, AA 2  is preferably D-Trp, AA 3  is Ile, AA 4  is preferably AlloIle, AA 5  is Asn, AA 6  is hCy, and AA 7  is preferably N-Me-Orn-ol, or a pharmaceutically acceptable salt or solvate thereof.

Claim (Index 8):
The solid phase process according to one or more of the preceding claims, wherein the process optionally comprises one or more purification steps, preferably one or more purification steps after step i) (namely after the cleavage and deprotection step) and/or one or more purification steps after step j) (namely after the cyclization step).

Metadata:
- Claim Count in Document: 19.0
- Percentile: 91.0
- Lexical Diversity: 1.65079
- Patent Class: 530.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11929494', '11457743', '13959931', '15145901', '11938776']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.669375192713793
- 35 USC 102 Novelty (BERT): 0.5305183656594327
- Combined Prediction Score: 0.655489510008357
- Mean Citation Score: 268.686994
- Max Citation Score: 288.8439
- Similarity Product: 148.54601000458004

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test