PATENT CLAIM ANALYSIS

Application Number: 15980165
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "649000"]

Abstract:
Disclosed are methods for the treatment of various solid tumors in patients in need of such treatment. The methods comprise administering to such a patient an NEDD8-activating enzyme (NAE) inhibitor such as ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]-pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate (MLN4924) or a pharmaceutically acceptable salt in combination with one or more chemotherapeutic agents. Also disclosed are medicaments for use in the treatment of various solid tumors.

Claim (Index 16):
The method of  claim 5 , wherein the amount of ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate or a pharmaceutically acceptable salt thereof administered on each of days 1, 3, and 5 of a 21 day schedule is less than or equal to 50 mg/m 2 .

Metadata:
- Claim Count in Document: 35.0
- Percentile: 93.0
- Lexical Diversity: 1.5614
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13667641', '12779331', '14432587', '14354149', '15249851']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7614358657126926
- 35 USC 102 Novelty (BERT): 0.5657317392665113
- Combined Prediction Score: 0.7418654530680745
- Mean Citation Score: 334.24532000000005
- Max Citation Score: 449.59985
- Similarity Product: 325.8482605041624

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test