PATENT CLAIM ANALYSIS

Application Number: 15890413
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["424", "172100"]

Abstract:
The present invention relates to a vaccine/inhibitor combination comprising an RNA vaccine comprising at least one RNA comprising at least one open reading frame (ORF) coding for at least one antigen and a composition comprising at least one PD-1 pathway inhibitor, preferably directed against PD-1 receptor or its ligands PD-L1 and PD-L2. The present invention furthermore relates to a pharmaceutical composition and a kit of parts comprising the components of such a vaccine/inhibitor combination. Additionally the present invention relates to medical use of such a vaccine/inhibitor combination, the pharmaceutical composition and the kit of parts comprising such a vaccine/inhibitor combination, particularly for the prevention or treatment of tumor or cancer diseases or infectious diseases. Furthermore, the present invention relates to the use of an RNA vaccine in therapy in combination with a PD-1 pathway inhibitor and to the use of a PD-1 pathway inhibitor in therapy in combination with an RNA vaccine.

Claim (Index 5):
The method of  claim 4 , wherein the carrier comprises protamine.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 88.0
- Lexical Diversity: 2.6129
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15890736', '14769720', '15124822', '13824502', '15136295']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7533294302662715
- 35 USC 102 Novelty (BERT): 0.5455590901576538
- Combined Prediction Score: 0.7325523962554097
- Mean Citation Score: 317.813184
- Max Citation Score: 404.7498
- Similarity Product: 291.93947114188666

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test