PATENT CLAIM ANALYSIS

Application Number: 15888768
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["514", "044000"]

Abstract:
The present invention relates generally to immunostimulatory nucleic acids, compositions thereof and methods of using the immunostimulatory nucleic acids. In particular the invention relates to palindrome-containing immunostimulatory nucleic acids and the use of these nucleic acids in treating disease.

Claim (Index 3):
A P-Class immunostimulatory CpG oligonucleotide having the formula\n 5\u2032 X-C1-C2 3\u2032 \n wherein:\n X is a 5\u2032 TLR activation domain; \n C1 is a 5\u2032 complementarity-containing region positioned immediately 3\u2032 to X that is at least 10 nucleotides in length; and \n C2 is a 3\u2032 complementarity-containing region that is at least 8 nucleotides in length; \n further wherein:\n C1 and C2 do not overlap and are connected to one another either directly or through a spacer (S); \n C1 and C2 form intermolecular duplexes that enable the oligonucleotide to spontaneously self-assemble under physiological conditions into a concatamer that consists of multiple copies of said oligonucleotide; \n the oligonucleotide includes at least one pyrimidine-purine (YpR) dinucleotide; and \n the oligonucleotide includes at least one stabilized internucleotide linkage selected from the group consisting of phosphorothioate, phosphorodithioate, methylphosphonate, and methylphosphorothioate.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 88.0
- Lexical Diversity: 1.61538
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15165963', '14046044', '12600368', '12442295', '10978283']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8507382121190515
- 35 USC 102 Novelty (BERT): 0.5376241791031185
- Combined Prediction Score: 0.8194268088174583
- Mean Citation Score: 387.509962
- Max Citation Score: 402.00934
- Similarity Product: 258.28732811228747

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test