PATENT CLAIM ANALYSIS

Application Number: 15768468
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "513000"]

Abstract:
The present invention relates to a combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof, in particular the S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, and more particularly the 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate, and a compound able to increase H 2 O 2  level in cancer cells of a subject, in particular for use for the treatment of cancer in a subject, wherein cancer cells of said subject do not overproduce H 2 O 2  in comparison to a control value and have a level of GSH below 5 nmol for 25000 cells.

Claim (Index 21):
The pharmaceutical composition according to  claim 6 , wherein:\n in said compound of formula (I), X1 and X2, identical or different, are chosen among a methyl, a phenyl, a benzyl, at least one of X1 or X2 being a methyl, or X1 and X2 together with the nitrogen atom to which they are linked form a piperidine or a morpholine; said compound of formula (I) is S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutical acceptable salt thereof; or said compound of formula (I) is 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.79032
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13546713', '15495670', '15120476', '15778213', '12981233']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7567125519391218
- 35 USC 102 Novelty (BERT): 0.494531947586058
- Combined Prediction Score: 0.7304944915038154
- Mean Citation Score: 191.747058
- Max Citation Score: 199.93008
- Similarity Product: 135.23339844723702

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test