PATENT CLAIM ANALYSIS

Application Number: 15893028
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["424", "093300"]

Abstract:
One embodiment provides a commensal gut production platform for ex vivo production of human gut commensal microbiota. Another embodiment provides devices, systems and methods for ex vivo culturing of gut microflora in a system that mimics the human gut environment. The culturing of the commensal microbiota in the disclosed systems produces gut microbiota having defined characteristics and properties that can be exploited to treat various conditions in a subject.

Claim (Index 32):
A system for the ex vivo production of human gut microbiota, comprising:\n a tortious, tubular ex vivo culture network comprising-hollow cartridges for culturing human gut microbiota, wherein the hollow cartridges are in the fluid communication and removably attached to the tortious tubular ex vivo culture network and comprise human gut microbiota and metabolites; a humidifying system in fluid communication with the tortious tubular ex vivo culture network to maintain physiological humidity inside the tortious tubular ex vivo culture network; a temperature regulation system in contact with the tortious tubular ex vivo culture network to regulate the temperature inside the tortious tubular ex vivo culture network to physiological temperature; and a hollow functional screening portal comprising extracellular matrix proteins, human cells, and metabolites generated by the microbiota in the tortious tubular ex vivo culture network, wherein the screening portal receives oxygen and other gases for culturing the human cells from a gas system in fluid communication with the tortious tubular ex vivo culture network; and a tunable, gas gradient of 0.8-2.0% oxygen or 2-60 mm Hg in the tortious tubular ex vivo culture network.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 88.0
- Lexical Diversity: 1.65909
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15656539', '15470214', '15090609', '15205007', '14773432']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6902340753888533
- 35 USC 102 Novelty (BERT): 0.5550787853067045
- Combined Prediction Score: 0.6767185463806383
- Mean Citation Score: 297.603918
- Max Citation Score: 427.3784
- Similarity Product: 292.48932909417147

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test