PATENT CLAIM ANALYSIS

Application Number: 16155939
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-08
Patent Classification: ["536", "007400"]

Abstract:
Described herein are processes for the preparation of compounds of formula (I): and pharmaceutically acceptable salts, solvates, and hydrates thereof.

Claim (Index 1):
A process for preparing a compound of formula (I) wherein\n R 1  is a monosaccharide or polysaccharide; \n A is \u2014CH 2 \u2014, \u2014C(O)\u2014, \u2014C(O)O\u2014, \u2014C(O)NH\u2014, \u2014S(O)2-, \u2014S(O)2NH\u2014, \u2014C(O)NHS(O)2-; \n B is \u2014(CH 2 ) n \u2014 where n is an integer ranging from 0-10, or B is an unsaturated carbon chain of 2-10 carbons, which may contain any alkenyl or alkynyl group; \n C represents 1 or 2 substituents independently selected in each instance from the group consisting of hydrogen, halogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, heteroarylalkyl, aminoaryl, alkylaminoaryl, acyl, acyloxy, sulfonyl, ureyl, and carbamoyl, each of which is optionally substituted; \n V is \u2014C(O)\u2014, \u2014C(\u2550NR 11 )\u2014, \u2014CH(NR 12 R 13 )\u2014, or \u2014N(R 14 )CH 2 \u2014; where R 11  is hydroxy or alkoxy, R 12  and R 13  are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, heteroarylalkyl; dimethylaminoalkyl, acyl, sulfonyl, ureyl, and carbamoyl; R 14  is hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, heteroarylalkyl, dimethylaminoalkyl, acyl, sulfonyl, ureyl, or carbamoyl; \n W is hydrogen, F, Cl, Br, I, or OH; \n X is hydrogen; and Y is OW; where R 7  is hydrogen, a monosaccharide, a disaccharide, alkyl, aryl, heteroaryl, acyl, or \u2014C(O)NR 8 R 9 , where R 8  and R 9  are each independently selected from hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, heteroalkyl, aryl, heteroaryl, heteroarylalkyl, alkoxy, dimethylaminoalkyl, acyl, sulfonyl, ureyl, and carbamoyl; or X and Y taken together with the attached carbon to form C\u2550O; and pharmaceutically acceptable salts, solvates, and hydrates thereof; \n the process comprising the step of (a) reacting a compound of formula (IV) \n wherein R 1  is a saccharide that includes a 2\u2032-hydroxyl group, with a sterically hindered acylating agent R 1a -L, wherein R 1a  is a sterically hindered acyl group and L is a leaving or activating group, to form the corresponding 2\u2032-acyl derivative.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.13043
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12739652', '15262277', '13722058', '10548698', '14725247']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6258408568280855
- 35 USC 102 Novelty (BERT): 0.5979775198752759
- Combined Prediction Score: 0.6230545231328046
- Mean Citation Score: 340.9517140000001
- Max Citation Score: 397.5458
- Similarity Product: 263.56840570299624

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test