PATENT CLAIM ANALYSIS

Application Number: 16181867
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["514", "220000"]

Abstract:
The present disclosure relates generally to derivatives of pyrrolobenzodiazepines and antibody-drug conjugates thereof and to methods of using these conjugates as therapeutics and/or diagnostics.

Claim (Index 27):
The conjugate of  claim 26 , wherein the compound of any one of the preceding claims, upon conjugation with the antibody or antibody fragment, is of Formula (VI), or a tautomer thereof, or a pharmaceutically acceptable salt or solvate of the compound or the tautomer, wherein: the antibody or antibody fragment is directly or indirectly linked to the compound at the position of one of E\u2033, D\u2033, R\u2033 7  or R\u2033 10 ; and the remaining of E\u2033, D\u2033, R\u2033 7  or R\u2033 10  are respectively E, D, R 7 , or R 10 ; wherein: E\u2033 is E or in which denotes direct or indirect linkage to the antibody or antibody fragment via a functional group of E;\n D\u2033 is D or \n in which denotes direct or indirect linkage to the antibody or antibody fragment via a functional group of D;\n R\u2033 7  is R 7  or \n in which denotes direct or indirect linkage to the antibody or antibody fragment via a functional group of R 7 ; and\n R\u2033 10  is R 10  or \n in which denotes direct or indirect linkage to the antibody or antibody fragment via a functional group of R 10 .

Metadata:
- Claim Count in Document: 65.0
- Percentile: 98.0
- Lexical Diversity: 1.19048
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15630068', '15597453', '14305643', '16061295', '15182444']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.780638365236591
- 35 USC 102 Novelty (BERT): 0.5630957165987648
- Combined Prediction Score: 0.7588841003728084
- Mean Citation Score: 360.17923
- Max Citation Score: 448.83072
- Similarity Product: 312.1786002935028

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test