PATENT CLAIM ANALYSIS

Application Number: 15911975
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-11
Patent Classification: ["514", "044000"]

Abstract:
A method of treating cancer in a subject is provided. The method includes administering a splice modulating oligonucleotide to the subject in an amount effective to provide a therapeutic benefit to the subject. In the method, the oligonucleotide modifies splicing of a pre-mRNA encoding a polypeptide promotes cancer cell survival, proliferation, and/or metastasis, or promotes angiogenesis, or a combination thereof; or increases expression of the polypeptide if the polypeptide inhibits angiogenesis, or a combination thereof. Similar methods of treating diseases involving prolactin or the prolactin receptor are also provided.

Claim (Index 20):
A single-stranded splice modulating oligonucleotide, wherein the oligonucleotide\n (i) is at least eight nucleotides in length; (ii) comprises at least eight contiguous nucleotides in a sequence that is at least 90% complementary to a target sequence in a prolactin receptor pre-mRNA; and (iii) comprises a modified oligonucleotide backbone.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 90.0
- Lexical Diversity: 1.81818
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14443360', '15833539', '14188168', '13144409', '15288415']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7624454682307057
- 35 USC 102 Novelty (BERT): 0.6460636482739825
- Combined Prediction Score: 0.7508072862350333
- Mean Citation Score: 443.8570820000001
- Max Citation Score: 711.38257
- Similarity Product: 556.6148612877828

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test