PATENT CLAIM ANALYSIS

Application Number: 16034517
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "320100"]

Abstract:
The invention relates to retroviral producer cells comprising nucleic acid sequences encoding: gag and pol proteins; envelope protein or a functional substitute thereof; and the RNA genome of the retroviral vector particle, wherein said nucleic acid sequences are all located at a single locus within the retroviral producer cell genome.

Claim (Index 4):
A method of producing a replication defective retroviral vector particle, comprising\n (a) introducing into a culture of mammalian host cells, a nucleic acid vector comprising a non-mammalian origin of replication and the ability to hold at least 25 kilobases (kb) of DNA, characterized in that said nucleic acid vector comprises retroviral nucleic acid sequences encoding: gag and pol proteins; and an env protein or a functional substitute thereof, wherein each of the retroviral nucleic acid sequences are arranged as individual expression constructs within the nucleic acid vector;\n (b) selecting within the culture for a mammalian host cell which has the nucleic acid sequences encoded on the vector integrated into an endogenous chromosome of the mammalian host cell; and \n (c) further culturing the mammalian host cell under conditions in which the replication defective retroviral vector particle is produced.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 95.0
- Lexical Diversity: 1.27907
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15356813', '10182644', '12021343', '10654537', '14378532']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6382131055167688
- 35 USC 102 Novelty (BERT): 0.5377931142979355
- Combined Prediction Score: 0.6281711063948855
- Mean Citation Score: 323.8894400000001
- Max Citation Score: 391.71066
- Similarity Product: 336.8334665472543

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test