PATENT CLAIM ANALYSIS

Application Number: 15943000
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-12
Patent Classification: ["435", "007200"]

Abstract:
Methods of detecting the presence of microorganisms in a sample, the methods including combining a sample, a reducing agent, an oxidant generator and a chemiluminescent agent, and in some cases a shielding agent, wherein the reducing agent both reduces the oxidant generator to produce an oxidant and reduces one or more disulfide bonds on a surface of a microorganism and wherein the oxidant oxidizes the chemiluminescent agent to produce a luminescent compound; and detecting the presence or absence of a signal to indicate the presence or absence of microorganisms in the sample, wherein the intensity of the chemiluminescent signal is inversely proportional to the amount of microorganisms in the sample.

Claim (Index 15):
A method of detecting the presence of a specific class, specific type, specific species or specific strain of microorganism in a sample, the method comprising:\n combining a first aliquot of a sample, a reducing agent, an oxidant generator and a chemiluminescent agent, wherein the reducing agent both reduces the oxidant generator to produce an oxidant and reduces one or more disulfide bonds on a surface of a microorganism and wherein the oxidant oxidizes the chemiluminescent agent to produce a luminescent compound; detecting the presence or absence of a first signal from the luminescent compound to indicate the presence or absence of total microorganisms in the first aliquot of the sample, wherein the intensity of the signal is inversely proportional to the amount of total microorganisms in the sample; combining a second aliquot of the sample with a shielding agent, the shielding agent comprising a receptor; and a macromolecular polymer, wherein the shielding agent binds via the receptor only to the specific class, specific type, specific species or specific strain of microorganism and not to other classes or other types, species or strains respectively of microorganisms in the sample; combining the second aliquot of the sample and the shielding agent with a reducing agent, an oxidant generator and a chemiluminescent agent, wherein the reducing agent both reduces the oxidant generator to produce an oxidant and reduces one or more disulfide bonds on surfaces of microorganisms not bound to the shielding agent and wherein the oxidant oxidizes the chemiluminescent agent to produce a luminescent compound; and detecting the presence or absence of a second signal.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 91.0
- Lexical Diversity: 2.40816
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13990828', '13670630', '14356406', '14813364', '12678579']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5724350365247074
- 35 USC 102 Novelty (BERT): 0.4820615870166602
- Combined Prediction Score: 0.5633976915739026
- Mean Citation Score: 159.30467800000002
- Max Citation Score: 161.8607
- Similarity Product: 106.57646519296168

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test