PATENT CLAIM ANALYSIS

Application Number: 15964400
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["568", "459000"]

Abstract:
The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral α,β-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral α,β-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R 1 , R 2 : are identical or different and are C 6 - to C 10 -aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C 1 - to C 6 -alkyl, C 3 - to C 6 -cycloalkyl, C 6 - to C 10 -aryl, C 1 - to C 6 -alkoxy and amino; Z is a group CHR 3 R 4  or aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C 1 - to C 6 -alkyl, C 3 - to C 6 -cycloalkyl, C 6 - to C 10 -aryl, C 1 - to C 6 -alkoxy and amino, wherein R 3  and R 4  are as defined in the claims and the description.

Claim (Index 22):
The composition of  claim 18 , wherein the chiral, bidentate bisphosphine ligand is a compound of the general formulae (IX), (X) or (XI): in which\n R 11 , R 12 : in each case independently of one another are an unbranched, branched or cyclic hydrocarbon radical having 1 to 20 carbon atoms which is saturated or can have one or more, generally 1 to about 4, nonconjugated, ethylenic double bonds and is unsubstituted or carries one or more, generally 1 to 4, identical or different substituents which are selected from OR 19 , NR 20 R 21 , halogen, C 6 -C 10 -aryl and C 3 -C 9 -hetaryl, or \n R 11  and R 12  together can also be a 2 to 10-membered alkylene group or a 3- to 10-membered cycloalkylene group, in which 1, 2, 3 or 4 nonadjacent CH 2  groups can be replaced by O or N\u2014R 9c , where the alkylene group and the cycloalkylene group are saturated or have one or two nonconjugated ethylenic double bonds, and where the alkylene group and the cycloalkylene group are unsubstituted or carry one or more identical or different substituents which are selected from C 1 - to C 4 -alkyl; \n R 13 , R 14 : are in each case independently of one another hydrogen or straight-chain or branched C 1 - to C 4 -alkyl and \n R 15 , R 16 , R 17 , R 18 : are identical or different and are C 6 - to C 10 -aryl which is unsubstituted or carries one or more substituents which are selected from C 1 - to C 6 -alkyl, C 3 - to C 6 -cycloalkyl, C 6 - to C 10 -aryl, C 1 - to C 6 -alkoxy and amino; \n R 19 , R 20 , R 21 : are in each case independently of one another hydrogen, C 1 -C 4 -alkyl, C 6 -C 10 -aryl, C 7 -C 12 -aralkyl or C 7 -C 12 -alkylaryl, where \n R 20 , R 21 : can together also be an alkylene chain having 2 to 5 carbon atoms, which can be interrupted by N or O.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 2.80645
- Patent Class: 568.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15536524', '11577068', '12597025', '11579692', '12449638']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6863133107332783
- 35 USC 102 Novelty (BERT): 0.6167757069545653
- Combined Prediction Score: 0.679359550355407
- Mean Citation Score: 332.548158
- Max Citation Score: 558.57587
- Similarity Product: 459.32473805939736

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test