PATENT CLAIM ANALYSIS

Application Number: 16298521
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "317100"]

Abstract:
Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (IA) are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having IA.

Claim (Index 10):
A method of detecting the presence of an  Aspergillus fumigatus, A. terreus , or  A. calidoustus  infection in a culture, the method comprising:\n obtaining a sample from the culture, e.g., gas from the headspace of the culture; determining the presence of one, two, three, or more, e.g., all, of the VOCs selected from the group consisting of camphene, \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, trans-geranylacetone, elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, 1,5,9-trimethyl cyclododecatriene, 9-decene-2-one and beta-sesquiphellandrene in the sample, wherein:\n the presence of one, two, three, or more, e.g., all, of \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, trans-geranylacetone indicates the presence of  A. fumigatus  in the culture; \n the presence of one, two, three, or more, e.g., all, of elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, and 1,5,9-trimethyl cyclododecatriene indicates the presence of  A. terreus  in the culture; and \n the presence of one or both of 9-decene-2-one and beta-sesquiphellandrene indicates the presence of  A. calidoustus  infection in the culture.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.27778
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316062', '14426678', '15023640', '14628125', '13261101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6059488909833002
- 35 USC 102 Novelty (BERT): 0.6458379322511704
- Combined Prediction Score: 0.6099377951100873
- Mean Citation Score: 408.262416
- Max Citation Score: 777.9191
- Similarity Product: 567.7921638996779

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test