PATENT CLAIM ANALYSIS

Application Number: 16204166
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-07
Patent Classification: ["544", "242000"]

Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Claim (Index 6):
A compound of  claim 1 , wherein Z is hydrogen or \u2014CH 2 M; wherein M is hydrogen, \u2014CN, \u2014NO 2 , \u2014OR 1 , protected hydroxy, \u2014CR\u2032R 1a R 2a , \u2014NR 1 R 2 , protected amino, \u2014CO 2 R 1 , or \u2014C(O)NR 1 R 2 ; R\u2032 is selected from the group consisting of hydrogen, optionally substituted \u2014C 1 -C 8  alkyl, optionally substituted \u2014C 2 -C 8  alkenyl, optionally substituted \u2014C 2 -C 8  alkynyl, optionally substituted \u2014C 3 -C 8  cycloalkyl, \u2014CN, \u2014OR 1 , and \u2014NR 1 R 2 ; R 1a  and R 2a  are independently selected from the group consisting of hydrogen, optionally substituted \u2014C 1 -C 8  alkyl, optionally substituted \u2014C 2 -C 8  alkenyl, optionally substituted \u2014C 2 -C 8  alkynyl, optionally substituted \u2014C 3 -C 8  cycloalkyl, optionally substituted 3- to 8-membered heterocyclic, optionally substituted aryl and optionally substituted heteroaryl; alternatively, R 1a  and R 2a  are taken together with the carbon atom to which they are attached to form an optionally substituted C 3 -C 10 -cycloalkyl or an optionally substituted 3 to 10-membered heterocyclic; and R 1  and R 2  are as defined in  claim 1 .

Metadata:
- Claim Count in Document: 32.0
- Percentile: 98.0
- Lexical Diversity: 1.73016
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15209150', '15088517', '15216124', '16194608', '15421777']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8502724730468845
- 35 USC 102 Novelty (BERT): 0.5468706133875643
- Combined Prediction Score: 0.8199322870809524
- Mean Citation Score: 392.076462
- Max Citation Score: 423.04852
- Similarity Product: 356.7539863879251

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test