PATENT CLAIM ANALYSIS

Application Number: 16180984
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "616000"]

Abstract:
The present invention includes pharmaceutical composition comprising (2R,2R′)-3,3′-disulfanediyl bis(2-acetamidopropanamide)(diNACA) or D 3 -N-acetyl cysteine amide, or a physiologically acceptable salt thereof, having a deuterium enrichment above the natural abundance of deuterium, and derivatives or solids thereof, and methods of using diNACA to treat eye diseases and other diseases associated with oxidative damage including, e.g., antivenom, beta-thallassemia, cataract, chronic obstructive pulmonary disease, macular degeneration, contrast-induced nephropathy, asthma, lung contusion, methamphetamine-induced oxidative stress, multiple sclerosis, Parkinson's disease, platelet apoptosis, Tardive dyskinesia, Alzheimer disease, HIV-1-associated dementia, mitochondrial diseases, myocardial myopathy, neurodegenerative diseases, pulmonary fibrosis, skin pigmentation, skin in need of rejuventation, antimicrobial infection, Friedreich's ataxia.

Claim (Index 8):
The pharmaceutical composition of  claim 1 , wherein the diNACA is a racemic mixture of (2R,2R\u2032)-3,3\u2032-disulfanediyl bis(2-acetamidopropanamide) and (2S,2S\u2032)-3,3\u2032-disulfanediyl bis(2-acetamidopropanamide).

Metadata:
- Claim Count in Document: 19.0
- Percentile: 98.0
- Lexical Diversity: 1.54348
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16137262', '12100555', '15176812', '16095262', '13993198']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7593300091615721
- 35 USC 102 Novelty (BERT): 0.4977398185876677
- Combined Prediction Score: 0.7331709901041817
- Mean Citation Score: 193.1586
- Max Citation Score: 225.95163
- Similarity Product: 159.69218441248296

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test