PATENT CLAIM ANALYSIS

Application Number: 16000322
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-11
Patent Classification: ["424", "480000"]

Abstract:
In various embodiments, the present invention is directed to oral pharmaceutical compositions. For example, in some embodiments, the present invention is directed to taste-masked compositions. In some embodiments, the taste masked compositions comprise a highly water soluble drug such as amphetamine, e.g., in the form of a salt such as amphetamine sulfate. In various embodiments, the present invention is directed to taste-masked, orally disintegrating compositions.

Claim (Index 22):
An orally disintegrating pharmaceutical composition comprising:\n (a) taste-masked drug containing particles comprising:\n (i) drug-containing core particles comprising a therapeutically effective amount of racemic amphetamine, or a pharmaceutically acceptable salt or ester thereof and at least one excipient; \n (ii) a first taste-masking membrane comprising ethylcellulose and excluding pharmaceutically acceptable gastrosoluble polymers, wherein the first taste-masking membrane is disposed on the drug-containing core particles and has a membrane thickness of from about 5% to about 10% by wt. of the taste-masked drug containing particle, and \n (ii) a second taste-masking membrane comprising ethylcellulose and aminoalkyl methacrylate copolymer at a ratio of about 50/50, wherein the second taste-masking layer is disposed on the first taste-masking membrane and the second taste-masking membranes has a thickness of from about 15% to about 30% by wt. of the taste-masked drug containing particle; \n (b) a disintegrant; (c) a sugar alcohol or saccharide, or mixture thereof; and wherein after administration the orally disintegrating pharmaceutical composition provide pharmacokinetic parameters within about 80-125% of one or more of AUC inf , C max , or T max  of an immediate release amphetamine sulfate tablet having an equivalent dose.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 94.0
- Lexical Diversity: 2.08108
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12772776', '11223819', '12057177', '14661639', '13844537']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7796753999417588
- 35 USC 102 Novelty (BERT): 0.5432769285575262
- Combined Prediction Score: 0.7560355528033356
- Mean Citation Score: 375.237624
- Max Citation Score: 407.90445
- Similarity Product: 316.9258853456854

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test