PATENT CLAIM ANALYSIS

Application Number: 15947680
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "462000"]

Abstract:
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.

Claim (Index 160):
The method of  claim 157 , wherein the DNA molecule comprising the nucleotide sequence that encodes the single molecule DNA-targeting RNA is a vector selected from the group consisting of: plasmids, cosmids, minicircles, phage, viral, retroviral, lentiviral, adenoviral, adeno-associated, and herpes simplex virus vectors.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 2.25424
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13842859', '14942782', '15138604', '15803424', '15925544']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4329723918676808
- 35 USC 102 Novelty (BERT): 0.6574594034948386
- Combined Prediction Score: 0.4554210930303966
- Mean Citation Score: 736.72044
- Max Citation Score: 778.5936
- Similarity Product: 584.4616723500252

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test