PATENT CLAIM ANALYSIS

Application Number: 15942312
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "293000"]

Abstract:
Methods for treating a subject having a cancerous tumor are disclosed. The methods comprise administering to the subject an effective amount of a non-steroidal selective glucocorticoid receptor modulator (SGRM) and an effective amount of a chemotherapeutic agent. The tumor may be cervical cancer. The SGRM may be a fused azadecalin. In embodiments, the SGRM may be a heteroaryl ketone fused azadecalin or an octahydro fused azadecalin.

Claim (Index 12):
The method of  claim 9 , wherein the octahydro fused azadecalin has the formula: wherein R 1  is a heteroaryl ring having from 5 to 6 ring members and from 1 to 4 heteroatoms each independently selected from the group consisting of N, O and S, optionally substituted with 1-4 groups each independently selected from R 1a ; each R 1a  is independently selected from the group consisting of hydrogen, C 1-6  alkyl, halogen, C 1-6  haloalkyl, C 1-6  alkoxy, C 1-6  haloalkoxy, N-oxide, and C 3-8  cycloalkyl; ring J is selected from the group consisting of an aryl ring and a heteroaryl ring having from 5 to 6 ring members and from 1 to 4 heteroatoms each independently selected from the group consisting of N, O and S; each R 2  is independently selected from the group consisting of hydrogen, C 1-6  alkyl, halogen, C 1-6  haloalkyl, C 1-6  alkoxy, C 1-6  haloalkoxy, C 1-6  alkyl-C 1-6  alkoxy, CN, OH, NR 2a R 2b , C(O)R 2a , C(O)OR 2a , C(O)NR 2a R 2b , SR 2a , S(O)R 2a , S(O) 2 R 2a , C 3-8  cycloalkyl, and C 3-8  heterocycloalkyl having from 1 to 3 heteroatoms each independently selected from the group consisting of N, O and S; alternatively, two R 2  groups on adjacent ring atoms are combined to form a heterocycloalkyl ring having from 5 to 6 ring members and from 1 to 3 heteroatoms each independently selected from the group consisting of N, O and S, wherein the heterocycloalkyl ring is optionally substituted with from 1 to 3 R 2c  groups; R 2a , R 2b  and R 2c  are each independently selected from the group consisting of hydrogen and C 1-6  alkyl; each R 3a  is independently halogen; and subscript n is an integer from 0 to 3, or salts and isomers thereof.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 90.0
- Lexical Diversity: 1.64444
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15915477', '15697878', '15236015', '15796443', '13901946']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8107506154755687
- 35 USC 102 Novelty (BERT): 0.629322859288857
- Combined Prediction Score: 0.7926078398568975
- Mean Citation Score: 434.382624
- Max Citation Score: 579.2803
- Similarity Product: 538.0052886665226

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test