PATENT CLAIM ANALYSIS

Application Number: 16247372
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["424", "529000"]

Abstract:
The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood/use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein.

Claim (Index 1):
A method for treating a subject in need thereof, by extracorporeal removal of a pathogenic microbe, said method comprising:\n a) contacting said subject's whole blood with heparin immobilized on a solid substrate, wherein heparin immobilization consists of a single covalent link of said terminal residue to said solid substrate by covalent end-point attachment, under conditions allowing binding of said pathogenic microbe in said subject's whole blood sample to the heparin; b) separating the whole blood from the solid substrate; c) recovering said whole blood containing a reduced amount of said pathogenic microbe; and d) reintroducing into said subject said whole blood containing a reduced amount of said pathogenic microbe.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 99.0
- Lexical Diversity: 3.29787
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12086126', '15678580', '14873133', '12665156', '14156255']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.746565463679409
- 35 USC 102 Novelty (BERT): 0.5896727757269548
- Combined Prediction Score: 0.7308761948841637
- Mean Citation Score: 354.586378
- Max Citation Score: 471.90384000000006
- Similarity Product: 441.7006110341549

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test