PATENT CLAIM ANALYSIS

Application Number: 16308128
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["424", "001110"]

Abstract:
Methods, and related compositions, for the improved synthesis of [ 18 F]DCFPyL are disclosed. Also provided are methods, and related compositions, for the use of [ 18 F]DCFPyL so produced.

Claim (Index 1):
A method of synthesizing 2-(3-{1-carboxy-5-[(6-[ 18 F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid ([ 18 F]DCFPyL), the method comprising:\n (i) radiofluorinating a DCFPyL precursor comprising ester moiety protecting groups to form a radiofluorinated DCPFPyL precursor; (ii) deprotecting the ester moiety protecting groups of the radiofluorinated DCPFPyL precursor of step (i) with phosphoric acid to form [ 18 F]DCFPyL in a reaction mixture; and (iii) purifying the [ 18 F]DCFPyL from the reaction mixture of step (ii) to provide [ 18 F]DCFPyL.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 98.0
- Lexical Diversity: 1.66667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15807306', '15127074', '14417749', '15323046', '13063741']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6602902427004226
- 35 USC 102 Novelty (BERT): 0.4922130104880806
- Combined Prediction Score: 0.6434825194791884
- Mean Citation Score: 183.478682
- Max Citation Score: 189.5713
- Similarity Product: 133.23736037139892

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test