PATENT CLAIM ANALYSIS

Application Number: 16133076
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "479000"]

Abstract:
Provided herein are compositions including oxotremorine (e.g., oxotremorine methiodide or Oxo-M) and 4-PPBP (e.g., 4-PPBP maleate). Also provided are methods of treating a connective tissue defect in a subject with oxotremorine and 4-PPBP. In addition, provided are scaffolds and methods of making same that include multiple fibers that include Oxo-M, 4-PPBP, and optionally icariin or kartogenin.

Claim (Index 35):
The method of  claim 34 , wherein the tissue defect is associated with a multi-tissue interface selected from the group consisting of musculoskeletal system; craniofacial system; periodontium; cementum (CM)-periodontal ligament (PDL)-alveolar bone (AB) complex; ligament-to-bone insertion; tendon-to-bone insertion; rotator cuff; supraspinatus tendon-to-bone interface; interface between tendon, fibrocartilage, or bone; supraspinatus tendon-fibrocartilage-bone interface; articular cartilage-to-bone junction; anterior cruciate ligament (ACL)-to-bone complex; anterior cruciate ligament-fibrocartilage-bone interface; intervertebral disc; nucleus pulposus-annulus fibrosus-endplates; cementum-periodontal ligament-alveolar bone; muscle-to-tendon; inhomogeneous or anisotropic tissues; knee meniscus; temporomandibular joint disc; periodontium; root-periodontium complex; synovial joints; or fibrocartilaginous tissues.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 1.65854
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13355055', '12583072', '15455792', '14855034', '11073275']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7728620808861925
- 35 USC 102 Novelty (BERT): 0.5040565477988119
- Combined Prediction Score: 0.7459815275774545
- Mean Citation Score: 230.73685
- Max Citation Score: 255.88966
- Similarity Product: 195.30140586201668

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test