PATENT CLAIM ANALYSIS

Application Number: 16192746
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["435", "440000"]

Abstract:
The invention relates to methods, uses, systems, arrays, engineered nucleotide sequences and vectors for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for treatment of microbes such as for environmental, medical, food and beverage use. The invention relates inter alia to methods of controlling micro biologically influenced corrosion (MIC) or biofouling of a substrate or fluid in an industrial or domestic system.

Claim (Index 16):
A method of treating or preventing an IBD in a human or animal subject, wherein the subject comprises a gut microbiota comprising  Klebsiella  bacteria cells, the method comprising:\n (a) contacting the  Klebsiella  cells in the microbiota with an engineered nucleic acid for producing a host modifying crRNA (HM-crRNA), and (b) producing the HM-crRNA in the  Klebsiella  cells; wherein (i) the HM-crRNA is operable with a Cas in the  Klebsiella  cells, wherein the engineered nucleic acid and the Cas are comprised by a HM-CRISPR/Cas system in the  Klebsiella  cells; (ii) the HM-crRNA comprises a nucleotide sequence that is capable of hybridizing to a target sequence in the  Klebsiella  cells to guide the Cas to cut the target sequence in the  Klebsiella  cells, thereby killing  Klebsiella  cells or inhibiting the growth of  Klebsiella  cells in the microbiota, whereby the proportion of  Klebsiella  cells in the microbiota is decreased.

Metadata:
- Claim Count in Document: 33.0
- Percentile: 98.0
- Lexical Diversity: 1.53968
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15160405', '15817125', '15460962', '15817142', '15817139']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7110681966273189
- 35 USC 102 Novelty (BERT): 0.5943932861520408
- Combined Prediction Score: 0.6994007055797911
- Mean Citation Score: 518.3866559999999
- Max Citation Score: 534.34753
- Similarity Product: 450.275842866574

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test