PATENT CLAIM ANALYSIS

Application Number: 16245960
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["424", "427000"]

Abstract:
The invention provides methods and polymer-containing formulations for treating retinal detachment and other ocular disorders, where the methods employ polymer compositions that can form a hydrogel in the eye of a subject. The hydrogel is formed by reaction of (a) a nucleo-functional polymer is a biocompatible polyalkylene polymer substituted by (i) a plurality of —OH groups, (ii) a plurality of thio-functional groups —R 1 —SH wherein R 1  is an ester-containing linker, and (iii) optionally one or more —OC(O)—(C 1 -C 6  alkyl) groups, such as a thiolated poly(vinyl alcohol) polymer and (ii) an electro-functional polymer that is a biocompatible polymer containing at least one thiol-reactive group, such as a poly(ethylene glycol) polymer containing alpha-beta unsaturated ester groups. Formulations are provided containing a nucleo-functional polymer, a poly(ethylene glycol) polymer, and an aqueous pharmaceutically acceptable carrier, for use in the therapeutic methods.

Claim (Index 18):
The method of  claim 16 , wherein the separate ocular formulations or the single ocular formulation comprises the nucleo-functional polymer in an amount of from about 0.5% w/v to about 15% w/v and the electro-functional polymer in an amount of from about 0.5% w/v to about 15% w/v.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 99.0
- Lexical Diversity: 1.93478
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13439969', '12390255', '12871923', '11399945', '11119463']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7130036800206968
- 35 USC 102 Novelty (BERT): 0.5088195408696121
- Combined Prediction Score: 0.6925852661055883
- Mean Citation Score: 209.77008800000004
- Max Citation Score: 223.64859
- Similarity Product: 145.20945269051313

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test