PATENT CLAIM ANALYSIS

Application Number: 15922921
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "135100"]

Abstract:
Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.

Claim (Index 8):
A method of treating cancer, an infectious disease or a T cell dysfunctional disorder comprising administering an antibody or antigen binding fragment to a patient suffering from a cancer, an infectious disease or a T cell dysfunctional disorder, wherein the antibody or antigen binding fragment is capable of binding to CD122 and common \u03b3 chain (\u03b3c), and wherein the antibody or antigen binding fragment is an IL-2 receptor agonist, and wherein the antibody or antigen-binding fragment comprises:\n (a) an antigen-binding fragment which binds to CD122, comprising: \n (i) a light chain variable region comprising the following CDRs: LC-CDR1: (SEQ ID NO: 2) TGTSSDIGHYDFVS   LC-CDR2: (SEQ ID NO: 3) DINNRPS   LC-CDR3: (SEQ ID NO: 4) SAYTSSDTLV; and   (ii) a heavy chain variable region comprising the following CDRs: HC-CDR1: (SEQ ID NO: 36) NYYMH   HC-CDR2: (SEQ ID NO: 37) AIMPSRGGTSYPQKFQG   HC-CDR3: (SEQ ID NO: 38) GEYYYDSSGYYY; (b) an antigen-binding fragment which binds to common \u03b3 chain, comprising:\n (i) a light chain variable region comprising the following CDRs: \n LC-CDR1: RSSQSLLHSNGYNYLD (SEQ ID NO:68) \n LC-CDR2: LGSNRDS (SEQ ID NO:69) \n LC-CDR3: MQGTHWPWT (SEQ ID NO:70); and \n (ii) a heavy chain variable region comprising the following CDRs: \n HC-CDR1: GYYWS (SEQ ID NO:48) \n HC-CDR2: EINHSGSTNYNPSLKS (SEQ ID NO:49) \n HC-CDR3: SPGGYSGGYFQH (SEQ ID NO:77).

Metadata:
- Claim Count in Document: 21.0
- Percentile: 90.0
- Lexical Diversity: 1.4
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15229336', '15750425', '15908218', '15521514', '15521685']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8334800178640471
- 35 USC 102 Novelty (BERT): 0.7659393073100623
- Combined Prediction Score: 0.8267259468086487
- Mean Citation Score: 795.537426
- Max Citation Score: 1009.92474
- Similarity Product: 889.5339545423877

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test