PATENT CLAIM ANALYSIS

Application Number: 16070073
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["424", "001690"]

Abstract:
There is provided a positron-emitting 18F-labelled Factor VII for non-invasive PET imaging of tumor TF expression in humans. More specifically the invention relates to human TFPET imaging of pancreatic cancer metastasis for diagnosis, staging, treatment monitoring and especially as an imaging biomarker for predicting prognosis, progression and recurrence.

Claim (Index 8):
A method of diagnosing by PET imaging a Tissue Factor expressing tumor in a human, said method comprising:\n administering a positron-emitting 18-F labelled factor VIIa (FVIIa) imaging agent, said agent comprising native human FVIIa or a variant thereof radiolabeled with 18-F, wherein the agent is administered in a dose of 50-400 MBq followed by PET scanning 1-6 hours after the agent has been administered, quantification through SUVmax and/or SUVmean for obtaining a PET image for the diagnosis of tumor tissue factor status.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 95.0
- Lexical Diversity: 1.20455
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10512215', '13803887', '12503893', '12178126', '14230128']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7251578723354974
- 35 USC 102 Novelty (BERT): 0.5099754086933885
- Combined Prediction Score: 0.7036396259712866
- Mean Citation Score: 251.50504
- Max Citation Score: 253.4652
- Similarity Product: 154.46987475278382

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test