PATENT CLAIM ANALYSIS

Application Number: 15881488
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["506", "002000"]

Abstract:
Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.

Claim (Index 15):
The method of  claim 1 , wherein a statistical difference is detected by computing a standard deviation and a mean value for the measurement for each of the one or more chromosomes of interest and for each of the one or more reference chromosomes, and comparing the mean value for each of the chromosomes of interest to the mean value of the reference chromosome in terms of the standard deviations.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.96341
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15881384', '15413200', '13949212', '15446778', '15191197']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6433070308218714
- 35 USC 102 Novelty (BERT): 0.5875686885554552
- Combined Prediction Score: 0.6377331965952298
- Mean Citation Score: 505.825778
- Max Citation Score: 532.1469999999998
- Similarity Product: 381.8696957954167

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test