PATENT CLAIM ANALYSIS

Application Number: 16134306
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["548", "429000"]

Abstract:
Compositions for the inhibition of SUV39H1 methyltransferase activity and methods of use thereof are provided. The disclosed compositions may be used for treating certain types of cancer, inducing apoptosis in a cancer cell, increasing cell sensitivity to FasL-induced apoptosis, and overcoming cancer cell resistance to apoptosis and/or certain types of cancer immunotherapy.

Claim (Index 3):
The compound of  claim 1 , wherein:\n R 1  and R 4  are each independently be selected from \u2014H, \u2014F, \u2014Cl, \u2014NO 2 , \u2014CH 3 , \u2014O\u2014(C 1 -C 12 )-alkyl, \u2014N\u2014(C 1 -C 12 )-alkyl, \u2014S\u2014(C 1 -C 12 )-alkyl, \u2014NH 2 , or \u2014COO\u2014(C 1 -C 12 )-alkyl, R 2  is selected from \u2014H, \u2014F, \u2014Cl, \u2014Br, \u2014I, \u2014O\u2014(C 1 -C 12 )-alkyl, \u2014N\u2014(C 1 -C 12 )-alkyl, \u2014S\u2014(C 1 -C 12 )-alkyl, \u2014(C 1 -C 12 )-alkyl, \u2014(C 3 -C 14 )-heteroaryl, \u2014(C 6 -C 14 )-aryl, R y \u2014CO\u2014 where R y  is a \u2014(C 1 -C 12 )-alkyl, \u2014(C 3 -C 6 )-cycloalkyl, or phenyl, or \u2014COO\u2014(C 1 -C 4 )-alkyl, X is \u2014CH or \u2014N, Z is selected from \u2014SO 2 , \u2014SO, \u2014(C 1 -C 12 ) alkyl, \u2014(C 1 -C 12 ) alkenyl, \u2014CO((CH 2 ) n ), \u2014O, or \u2014SOCH 3 , where n is 1 to 12, and Y is selected from \u2014C\u2550O\u2014C\u2550O, \u2014(C 1 -C 2 )-alkyl, or \u2014CH\u2550CH\u2014.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 97.0
- Lexical Diversity: 1.46154
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11622229', '13216927', '14905726', '14764236', '12981233']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7579633597399046
- 35 USC 102 Novelty (BERT): 0.5121658190276249
- Combined Prediction Score: 0.7333836056686766
- Mean Citation Score: 276.1742540000001
- Max Citation Score: 291.8761
- Similarity Product: 207.420801442349

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test