PATENT CLAIM ANALYSIS

Application Number: 16158752
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["536", "025410"]

Abstract:
Methods for processing polynucleotide-containing biological samples, and materials for capturing polynucleotide molecules such as RNA and/or DNA from such samples. The RNA and/or DNA is captured by polyamindoamine (PAMAM (Generation 0)) bound to a surface, such as the surface of magnetic particles. The methods and materials have high efficiency of binding RNA and of DNA, and of release, and thereby permit quantitative determinations.

Claim (Index 2):
A method for nucleic acid isolation comprising:\n receiving into a process chamber a biological sample containing nucleic acid; contacting the biological sample with a plurality of binding particles in the process chamber, the binding particles being coated with PAMAM (Generation 0) dendrimer which is amide-bonded to the binding particles, wherein at least a portion of the nucleic acids in the biological sample become reversibly bonded to the binding particles; washing the binding particles with a solution characterized by a pH less than 10 while retaining the nucleic acid on the binding particles; and releasing a nucleic acid sample from the binding particles by contacting the binding particles with an elution solution characterized by a pH greater than 10.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.57447
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14262525', '13692980', '12172214', '14976746', '15173880']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.754598146343295
- 35 USC 102 Novelty (BERT): 0.5121562334943492
- Combined Prediction Score: 0.7303539550584005
- Mean Citation Score: 313.05503
- Max Citation Score: 340.80875
- Similarity Product: 275.0995482043922

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test