PATENT CLAIM ANALYSIS

Application Number: 15913087
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["514", "216000"]

Abstract:
The present invention relates to compounds of formula hetaryl is a five membered heteroaryl group, containing 1 to 3 heteroatoms, selected from O, S or N; R 1  is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkyl substituted by halogen, S-lower alkyl substituted by halogen or lower alkoxy substituted by halogen,     or two neighboring carbon atoms may form on phenyl an additional ring containing —O—CH 2 —O—;       n is 1 to 5; R 2  is hydrogen or lower alkyl substituted by halogen; R 3  is hydrogen or lower alkyl substituted by halogen; or to pharmaceutically active acid addition salts thereof, to racemic mixtures or to its corresponding enantiomers or optical isomers or stereoisomers thereof. The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome.

Claim (Index 10):
A process for preparing a compound of formula I as defined in any one of  claims 1 - 9 , which process comprises\n a) reducing a compound of formula by catalytic hydrogenation or with Mg in methanol in the presence of iodine to a compound of formula wherein the substituents have the meaning as described above and,\n if desired, converting the compounds obtained into pharmaceutically acceptable acid addition salts; \n or\n b) reacting a compound of formula \n with a compound of formula to a compound of formula wherein the groups have the meaning as described above, or\n c) reacting a compound of formula \n with a compound of formula to a compound of formula wherein the groups have the meaning as described above, and, if desired converting the compounds obtained into pharmaceutically acceptable acid addition salts.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 90.0
- Lexical Diversity: 1.83516
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16339345', '11715440', '13405404', '12356940', '12200731']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8078038157731964
- 35 USC 102 Novelty (BERT): 0.5763716379017909
- Combined Prediction Score: 0.7846605979860559
- Mean Citation Score: 429.80002
- Max Citation Score: 463.26755
- Similarity Product: 398.68780253980464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test