PATENT CLAIM ANALYSIS

Application Number: 15907432
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["544", "405000"]

Abstract:
The present invention relates to compounds of formula (I) wherein R 1 , R 2 , and Z −  have one of the meanings as indicated in the specification or a pharmaceutically acceptable salt thereof, to the use of compounds of formula (I) as a medicament, to pharmaceutical composition comprising at least one compound of formula (I), as well as to medicament combinations containing one or more compounds of formula (I).

Claim (Index 1):
A method for the treatment of a disease selected from among respiratory diseases or complaints, allergic diseases of the airways and dry eyes comprising administering a therapeutically effective amount of a compound of formula (I), wherein\n R 1  and R 2  are independently selected from hydrogen and C 1 -C 6 -alkyl, wherein C 1 -C 6 -alkyl may carry 1 to 5 substituents selected from hydroxyl, amino, C 1 -C 4 -alkylamino, di-C 1 -C 4 -alkylamino, morpholin-4-yl and dimethylphosphinoylmethoxy, provided that at least one of R 1  and R 2  is different from hydrogen, unsubstituted C 1 -C 6 -alkyl and C 1 -C 6 -alkyl carrying 1 hydroxyl substituent; or \n R 1  and R 2  together with the nitrogen atom they are attached to form a heterocyclic moiety selected from piperidine, piperazine and 1,4-diazepane, wherein the heterocyclic moiety may carry 1 or 2 substituents selected from C 1 -C 4 -alkyl, dimethylphosphinoyl-C 1 -C 4 -alkyl and NR a R b , wherein R a  and R b  are independently selected from hydrogen, C 1 -C 4 -alkyl and \u2014C(O)CH 2 NR c R d , wherein R c  and R d  are independently selected from hydrogen and C 1 -C 4 -alkyl; and \n Z \u2212  is selected from chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate and p-toluenesulfonate; \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 88.0
- Lexical Diversity: 1.80435
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15654301', '15542908', '15542896', '15542894', '15241146']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7129639239403924
- 35 USC 102 Novelty (BERT): 0.480874247977632
- Combined Prediction Score: 0.6897549563441164
- Mean Citation Score: 191.49208
- Max Citation Score: 195.71094
- Similarity Product: 151.26579922134874

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test