PATENT CLAIM ANALYSIS

Application Number: 15918620
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "167000"]

Abstract:
The method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering, as necessary, both Vitamin D repletion and Vitamin D hormone replacement therapies, is disclosed. The blood concentrations of 25-hydroxyvitamin D are increased to and maintained at or above 30 ng/mL, and blood concentrations of 1,25-dihydroxyvitamin D are increased to or maintained within a patient's normal historical physiological range for 1,25-dihydroxyvitamin D without causing substantially increased risk of hypercalcemia, hyperphosphatemia or over suppression of plasma iPTH in the patient. The blood levels of 25-hydroxyvitamin D are maintained at or above 30 ng/mL between doses of Vitamin D repletion therapies, and the blood levels of 1,25-dihydroxyvitamin D are maintained in the patient's normal historical physiological range between doses of Vitamin D hormone replacement therapies. In one aspect, the disclosure includes methods wherein the blood concentration of 25-hydroxyvitamin D during treatment comprises predominantly 25-hydroxyvitamin D 3 , and/or wherein the method includes administering predominantly or solely 25-hydroxyvitamin D 3  for 25-hydroxyvitamin D repletion and/or maintenance.

Claim (Index 6):
The pharmaceutical dosage form of  claim 5 , wherein the active Vitamin D hormone comprises 1,25-dihydroxyvitamin D 3 .

Metadata:
- Claim Count in Document: 62.0
- Percentile: 90.0
- Lexical Diversity: 2.52632
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15220963', '13680997', '12305572', '15231357', '12597224']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8407916803224933
- 35 USC 102 Novelty (BERT): 0.6202652962597927
- Combined Prediction Score: 0.8187390419162233
- Mean Citation Score: 588.7778000000002
- Max Citation Score: 655.2842400000002
- Similarity Product: 480.3170467735006

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test