PATENT CLAIM ANALYSIS

Application Number: 16087861
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-04
Patent Classification: ["514", "210210"]

Abstract:
Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer.

Claim (Index 12):
The compound, the pharmaceutically acceptable salt, the hydrate or the prodrug thereof as defined in  claim 1 , wherein, R 2  is selected from H, F, Cl, Br, I, CN, NO 2 , OH, COOH, NH 2 , or the group consisting of C 1-4  alkyl, C 1-4  alkoxy, C 1-4  alkylthio, NH(C 1-4  alkyl), N,N-di(C 1-3  alkyl)amino and C 3-6  cycloalkyl, each of which is optionally substituted with 1, 2, or 3 R, and/or,\n R 3  is selected from H, F, Cl, Br, I, CN, NO 2 , OH, COOH, NH 2 , or the group consisting of C 1-4  alkyl, C 1-4  alkoxy, C 1-4  alkylthio, NH(C 1-4  alkyl), N,N-di(C 1-3  alkyl)amino, C 3-6  cycloalkyl, 3-6 membered heterocycloalkyl, 5-6 membered aryl and 5-6 membered heteroaryl, each of which is optionally substituted with 1, 2, or 3 R, and/or, R 4  and R 5  are each independently selected from H, F, Cl, Br, I, CN, NO 2 , OH, COOH, NH 2 , or the group consisting of C 1-4  alkyl, C 1-4  alkoxy, C 1-4  alkylthio, NH(C 1-4  alkyl), N,N-di(C 1-3  alkyl)amino and C 3-6  cycloalkyl, each of which is optionally substituted with 1, 2, or 3 R, and/or, ring A is selected from the group consisting of phenyl, pyridyl, pyrazinyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, thienyl, benzofuranyl, benzothienyl, indolyl, benzimidazolyl, benzothiazolyl, purinyl, quinolinyl and isoquinolinyl, and/or, R 6  is selected from

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.28571
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16343387', '10465426', '10420399', '11585598', '12245305']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8443120095561458
- 35 USC 102 Novelty (BERT): 0.5520906548250669
- Combined Prediction Score: 0.815089874083038
- Mean Citation Score: 398.579302
- Max Citation Score: 429.7016
- Similarity Product: 327.6124529848098

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test