PATENT CLAIM ANALYSIS

Application Number: 15771479
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "619000"]

Abstract:
The present application relates to novel fluorinated amide derivatives of Formula (I), to processes for preparing them, pharmaceutical compositions containing them, and their use thereof in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and memory deficits, as well as chronic and acute pain and other related CNS disorders.

Claim (Index 1):
A compound of Formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or optical isomer, or combination thereof: wherein: R 1  is selected from the group consisting of H, hydroxy, halogen, cyano, nitro, CO 2 R 6 , CONHR 6 , CON(R 6 ) 2 , SO 2 NHR 6 , SO 2 N(R 6 ) 2 , C 1 -C 6 -lower alkyl, C 1 -C 6 -lower alkoxy, C 1 -C 6 -lower alkyl-ester, C 1 -C 6 -lower alkyl-amide, C 1 -C 6 -lower alkyl-acid, C 1 -C 6 -lower haloalkyl, C 1 -C 6 -lower haloalkoxy, C 1 -C 6 -lower haloalkyl-ester, cycloalkyl, heterocycloalkyl, bicycloalkyl, heterobicycloalkyl, aryl, heteroaryl, hydroxyalkyl, hydroxycycloalkyl, hydroxy-heterocycloalkyl, cyanoalkyl, alkenyl, alkynyl, cycloalkenyl, heterocycloalkenyl, alkylenearyl, alkyleneheteroaryl, alkylene-O-alkyl, alkylene-O-cycloalkyl, alkylene-O-heterocycloalkyl, alkylene-O-alkylene-cycloalkyl, alkylene-O-alkylene-heterocycloalkyl, optionally substituted with one or more independently-selected groups R 6 ; R 2  and R 3  are each independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteoaryl; or R 2  and R 3  connect to form, together with the carbon atom to which they are attached, a three to seven-membered ring; and R 4  and R 5  are each independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteoaryl; or R 4  and R 5  connect to form, together with the nitrogen atom to which they are attached, a three to seven-membered ring; Q is selected from O, NR 7 , S, SO and SO 2 ; and R 6  and R 7  are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteoaryl.

Metadata:
- Claim Count in Document: 46.0
- Percentile: 91.0
- Lexical Diversity: 1.35849
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15771465', '13899469', '12884963', '13287635', '15846198']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.776219422108801
- 35 USC 102 Novelty (BERT): 0.5294834291191826
- Combined Prediction Score: 0.7515458228098393
- Mean Citation Score: 286.733794
- Max Citation Score: 332.76163
- Similarity Product: 244.10695694236875

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test