PATENT CLAIM ANALYSIS

Application Number: 15936354
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["435", "007100"]

Abstract:
The present invention relates to biomarkers and diagnostic and prognostic methods for Alzheimer's disease and other neurodegenerative disorders. The invention also provides compositions for detecting the biomarker as well as compositions and methods useful for treating Alzheimer's disease and other neurodegenerative disorders.

Claim (Index 1):
A method of analyzing a sample from a subject comprising the steps of: (i) obtaining a biological sample comprising vesicles from the subject, (ii) measuring the level of one or more biomarkers in the biological sample, and (iii) comparing the level of the one or more biomarkers in the biological sample to a control level of the one or more biomarkers in a control biological sample, wherein at least one of the one or more biomarkers is selected from the group consisting of Tau, phosphorylated Tau, A\u00df1-42, TDP-43, \u03b1-synuclein, SOD-1, FUS, FKBP51, IRS-1, phosphorylated IRS-1, CTSD, LAMP1, UBP, HSP70, NSE, NFL, CD9, CD63, CD81, and CD171.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 1.64286
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14522585', '15179761', '15878351', '15600959', '13807963']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5912697753881065
- 35 USC 102 Novelty (BERT): 0.645896004479669
- Combined Prediction Score: 0.5967323982972628
- Mean Citation Score: 405.004586
- Max Citation Score: 652.3273
- Similarity Product: 568.6733983848095

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test