PATENT CLAIM ANALYSIS

Application Number: 15777223
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "030000"]

Abstract:
The invention provides novel compounds that are derivatives of Azithromycin and that have been found by the current inventors to have low antimicrobial activity but significant epithelial barrier enhancement properties. The invention further provides use of the compounds as a medicament, in particular in the treatment or prophylaxis of a disease or condition that is caused by a defect in epithelial cells or tissue, or a disease or condition that benefits from enhancement or restoration of epithelial barrier function, for example diseases of the respiratory tract.

Claim (Index 28):
The method of  claim 27  wherein the disease or condition is an inborn, chronic, persistent or prolonged airway disease selected from the group consisting of asthma, chronic obstructive pulmonary disease (COPD), Cystic Fibrosis (CF), non-CF Bronchiectasis, chronic rhinosinusitis, diffuse panbronchiolitis (DPB), chronic bronchitis, Bronchiolitis Obliterans Organizing Pneumonia (BOOP) primary or secondary to chemotherapy or post-transplantation status, infantile respiratory distress syndrome (IRDS) and its long term complication, bronchopulmonary dysplasia, neuromuscular respiratory depression and/or failure, pneumonia (particularly community-acquired pneumonia) and conditions caused by and associated with Respiratory Syncytial Virus (RSV) and related viruses, for example the Human-Meta-Pneumo Virus, such as chronic infantile wheezing and associated childhood asthma bronchial hyperreactivity.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.625
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14902129', '10421577', '10218154', '10840529', '09485292']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8507016271205684
- 35 USC 102 Novelty (BERT): 0.5371006602990864
- Combined Prediction Score: 0.8193415304384203
- Mean Citation Score: 400.387328
- Max Citation Score: 434.61444000000006
- Similarity Product: 198.1933680800557

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test