PATENT CLAIM ANALYSIS

Application Number: 15768468
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "513000"]

Abstract:
The present invention relates to a combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof, in particular the S-methyl 4-(dimethylamino)-4-methylpent-2-ynethioate or a pharmaceutically acceptable salt thereof, and more particularly the 4-(Dimethylamino)-4-methyl-2-pentynethioic acid S-methyl ester fumarate, and a compound able to increase H 2 O 2  level in cancer cells of a subject, in particular for use for the treatment of cancer in a subject, wherein cancer cells of said subject do not overproduce H 2 O 2  in comparison to a control value and have a level of GSH below 5 nmol for 25000 cells.

Claim (Index 19):
The method according to  claim 2 , wherein cancer cells of said subject have also a MDA-adducts level above 75 ng per \u03bcg of total protein and/or a HNE-adducts level above 1 \u03bcg per \u03bcg of total protein, after in vitro treatment with a compound of formula (I) or a pharmaceutical acceptable salt thereof.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.79032
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13546713', '15495670', '15120476', '15778213', '12981233']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7559019338044218
- 35 USC 102 Novelty (BERT): 0.4989119395625527
- Combined Prediction Score: 0.730202934380235
- Mean Citation Score: 191.747058
- Max Citation Score: 199.93008
- Similarity Product: 128.6791200943565

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test