PATENT CLAIM ANALYSIS

Application Number: 15871218
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "019300"]

Abstract:
The present invention discloses a polypeptide compound, a preparation method and an application thereof. The structural formula of the polypeptide compound is (X A X B X C X D X E X F X G —X) 2 KY or {(X A X B X C X D X E X F X G —X) 2 K} 2 KY or {({X A X B X C X D X E X F X G —X} 2 K) 2 K} 2 KY, where, X A , X B , X D , X E  and X G  are one of aliphatic amino acid molecules respectively, X C  and X F  are aliphatic amino acid molecules or heterocyclic amino acid molecules, K is lysine (Lys, K), X or Y is null or any one or more amino acid or chemical groups. The polypeptide compound provided in the invention has an effect of enhancing the immune function of a body and has an application potential of being developed into a clinical medicine capable of enhancing the immune function of a body.

Claim (Index 17):
A method for preparing the polypeptide compound according to  claim 1 , wherein, a synthesis route of the {(X A X B X C X D X E X F X G \u2014X) 2 K} 2 KY structure is expressed by formula 2: Y is first fixed to WANG solid resin first, and then is bonded with lysine Fmoc-Lys(Fmoc)-OH by condensation, to form a two-branch skeleton \u201c>KY-WANG solid resin\u201d with branch nodes; then, the two active terminal amino groups of K in the \u201c>KY-WANG solid resin\u201d are bonded with the terminal carboxyl groups of lysine Fmoc-Lys(Fmoc)-OH by condensation, to form a four-branch skeleton \u201c>K 2 KY-WANG solid resin\u201d with two branch nodes; next, the two active terminal amino groups of each lysine K in the \u201c>K 2 KY-WANG solid resin\u201d are bonded with a X A X B X C X D X E X F X G \u2014X segment respectively, to form a four-branch peptide (X A X B X C cX D X E X F X G \u2014X) 2 KY-WANG solid resin; or the two active terminal amino groups of K in the \u201c>K 2 KY-WANG solid resin\u201d are bonded with amino acids X, X G , X F , X E , X D , X C , X B , X A  by condensation in sequence, to obtain a (X A X B X C X D X E X F X G \u2014X)4K 2 KY-WANG solid resin; finally, the four-branch peptide is cracked from the WANG solid resin and is purified, to obtain a polypeptide compound {(X A X B X C X D X E X F X G \u2014X) 2 K} 2 KY with four copies of X A X B X C X D X E X F X G \u2014X.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 2.92754
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15852288', '13168453', '11721910', '15320112', '15129846']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7585211308413957
- 35 USC 102 Novelty (BERT): 0.5595517091724483
- Combined Prediction Score: 0.7386241886745011
- Mean Citation Score: 241.150632
- Max Citation Score: 417.65292
- Similarity Product: 402.6433489079333

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test