PATENT CLAIM ANALYSIS

Application Number: 15766477
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["250", "288000"]

Abstract:
Under the control of an analysis control unit ( 5 ), a mass spectrometer unit ( 2 ) performs a product-ion scan measurement for a target component in a target sample within a time range where the component is introduced. It also performs a scan measurement over an m/z range including the m/z of an ion originating from a standard component within the same segment of time. A mass correction information calculator ( 42 ) calculates mass correction information from measured and theoretical values of the m/z of the ion originating from the standard component observed on an MS spectrum obtained by the scan measurement. Using the mass correction information, a mass corrector ( 43 ) corrects the m/z of each ion peak originating from the target component observed on an MS/MS spectrum obtained by the product-ion scan measurement performed within the same cycle as the scan measurement concerned. It is possible to consider that the MS measurement and the MS/MS measurement within the same cycle have been almost simultaneously carried out. Accordingly, a mass correction which is almost equivalent to an internal standard method can be achieved.

Claim (Index 6):
A tandem mass spectrometer including: a first mass separator for selecting, as a precursor ion, an ion having a specific mass-to-charge ratio from ions originating from a sample; a collision cell for dissociating the precursor ion; and a second mass separator for performing a mass spectrometry analysis of various product ions generated by the dissociation, the tandem mass spectrometer further comprising:\n a) a first analysis controller for controlling relevant sections to perform a scan measurement for carrying out a mass scan over a predetermined mass-to-charge-ratio range in the first mass separator or the second mass separator without dissociating an ion within the collision cell; b) a second analysis controller for controlling relevant sections to perform a scan measurement for carrying out a mass scan over a predetermined mass-to-charge-ratio range in the second mass separator while dissociating an ion within the collision cell; and c) a correction processor for correcting a mass-to-charge ratio of a product ion originating from a component in a target sample obtained by performing the product-ion scan measurement for the component under a control of the second analysis controller at a point in time where a predetermined period of time elapses from a beginning of the measurement, using a mass-to-charge ratio of an ion originating from a standard component whose mass is precisely known, where the latter mass-to-charge ratio is obtained by performing the scan measurement for a sample containing the standard component under a control of the first analysis controller at a point in time where the predetermined period of time elapses from a beginning of the measurement.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 91.0
- Lexical Diversity: 2.26437
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13589989', '13145769', '14718842', '14508086', '15747465']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.753159248714297
- 35 USC 102 Novelty (BERT): 0.5094511190246568
- Combined Prediction Score: 0.7287884357453329
- Mean Citation Score: 317.655168
- Max Citation Score: 328.36942
- Similarity Product: 307.9190620752287

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test