PATENT CLAIM ANALYSIS

Application Number: 15977569
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "050000"]

Abstract:
The invention provides a new bioorthogonal deprotection method for preparing heterocyclic compounds by bond cleavage using palladium. The methods have general application in the field of biological synthetic chemistry. Compounds, such as prodrugs, which are useful in such methods are also provided.

Claim (Index 5):
A method of treatment, wherein the method comprises co-administering a first compound comprising a first group defined according to formula (II): bonded to a second group defined according to formula (III) at the positions indicated by asterisks or composition comprising the first compound and a source of palladium to a subject, whereby the first compound reacts with the palladium in the source of palladium within the subject to release a drug selected from the group consisting of 5-fluorouracil, olaparib, ropinirole, pemetrexed, milrinone, amrinone, aciclovir, iodoxuridine, sunitinib, pimobendan, enoximone, cilostazol, nitrofurantoin, aripiprazole, sertindole, ziprasidone, mosapramine, phenobarbital, methylphenobarbital, primidone, lorazepam, nitrazepam, clonazepam, ethotoin, phenytoin, mephenytoin, fosphenytoin, floxuridine, flucytosine, stavudine, telbivudine, zidovudine, trifluridine, entecavir and uramustine; or a derivative thereof.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 1.20513
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14901314', '10541328', '14428501', '14764236', '14156314']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7277238481373366
- 35 USC 102 Novelty (BERT): 0.5191401081730078
- Combined Prediction Score: 0.7068654741409037
- Mean Citation Score: 251.51086400000003
- Max Citation Score: 262.73773
- Similarity Product: 162.57610531075838

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test