PATENT CLAIM ANALYSIS

Application Number: 15744485
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "492000"]

Abstract:
Methods for reducing platinum drug-induced toxicity in a cell expressing Organic Cation Transporter 2 (OCT2), methods for reducing platinum drug-induced toxicity in a subject, methods for treating cancer, methods for increasing efficacy of platinum drug treatment in a subject, and pharmaceutical compositions are described. The described methods and compositions include an OCT2 inhibitor where the OCT2 inhibitor is buflomedil or a salt thereof, dolutegravir or a salt thereof contains an imidazole, or is miconazole or a salt thereof.

Claim (Index 76):
The pharmaceutical composition of any of  claims 72 - 75 , further comprising a therapeutically effective amount of one or more additional cancer chemotherapeutic agents in addition to the platinum drug.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 86.0
- Lexical Diversity: 1.83333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12836398', '13147751', '14175295', '11638193', '15314200']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.767183736959874
- 35 USC 102 Novelty (BERT): 0.4998196977116375
- Combined Prediction Score: 0.7404473330350504
- Mean Citation Score: 256.733086
- Max Citation Score: 260.66200000000003
- Similarity Product: 196.90791287851337

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test