PATENT CLAIM ANALYSIS

Application Number: 15923951
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["800", "015000"]

Abstract:
Materials and methods for making multiplex gene edits in cells and are presented. Further methods include animals and methods of making the same. Methods of making chimeric animals are presented, as well as chimeric animals.

Claim (Index 25):
A method of introducing multiple gene edits in a cell or embryo comprising simultaneously introducing into the cell\n a first targeted endonuclease directed to a first target chromosomal DNA site and a first homology directed repair (HDR) template that has homology to the first target chromosomal DNA site; and a second targeted endonuclease directed to a second target chromosomal DNA site and a second HDR template that has homology to the second target chromosomal DNA site wherein the first HDR template replaces the first target chromosomal DNA site and the second HDR template replaces the second target chromosomal DNA site.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 90.0
- Lexical Diversity: 1.625
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14263446', '14991818', '14013250', '15354270', '14515503']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5757058903550475
- 35 USC 102 Novelty (BERT): 0.516445139731991
- Combined Prediction Score: 0.5697798152927419
- Mean Citation Score: 247.29948800000005
- Max Citation Score: 345.777
- Similarity Product: 251.65044530797005

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test