PATENT CLAIM ANALYSIS

Application Number: 16037429
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["424", "489000"]

Abstract:
A method of designing a pharmaceutical composition for providing the liver of a person or animal, as a therapeutic target, with a predetermined concentration of a sulfate or sulfonate of a pharmacologically active agent, during a predetermined period, includes determining the correlation between the solubility of a sulfate and/or sulfonate of a pharmacologically active agent of the formula D n+ (R 1 SO 3 ) − n  or D n+ (R 2 OSO 3 ) − n  for various carbon chain lengths X, Y in an aqueous solvent and the expected concentration of the pharmaceutically active agent D in the therapeutic target upon administration of the pharmacologically active agent D to the person or animal, defining a target solubility of the sulfate or sulfonate based on a desired concentration of said pharmaceutically active substance D in the therapeutic target, and determining the carbon chain length(s) X, Y corresponding to the target solubility.

Claim (Index 9):
The method of  claim 1 , wherein R 2  is straight chain C 10 -C 20  alkyl.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 95.0
- Lexical Diversity: 2.27397
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15509875', '15300688', '12809259', '13623473', '14116182']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7144367808512899
- 35 USC 102 Novelty (BERT): 0.6050686283671717
- Combined Prediction Score: 0.7034999656028781
- Mean Citation Score: 255.280678
- Max Citation Score: 580.5892
- Similarity Product: 451.0722383580208

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test