PATENT CLAIM ANALYSIS

Application Number: 15925348
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["424", "489000"]

Abstract:
The present invention relates to novel methods of using microporous zirconium silicate to reduce the risk of hyperkalemia and to lower aldosterone levels in the treatment of chronic kidney disease and/or chronic heart disease with therapies comprising diuretics. The invention provides a safe way to reduce the risk of hyperkalemia and to lower aldosterone. The invention also relates to treatment of other conditions that can occur either alone or in connection with hyperkalemia, chronic kidney disease, and/or chronic heart disease.

Claim (Index 61):
A method for treating chronic kidney or chronic heart disease comprising administering to a patient in need thereof a first agent selected from an angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB), and a second agent comprising zirconium silicate of formula (I):\n A p M x Zr 1-x Si n Ge y O m \u2003\u2003(I) where\n A is a potassium ion, sodium ion, rubidium ion, cesium ion, calcium ion, magnesium ion, \n hydronium ion or mixtures thereof,\n M is at least one framework metal, wherein the framework metal is hafnium (4+), tin (4+), niobium (5+), titanium (4+), cerium (4+), germanium (4+), praseodymium (4+), terbium (4+) or mixtures thereof, \n \u201cp\u201d has a value from about 1 to about 20, \n \u201cx\u201d has a value from 0 to less than 1, \n \u201cn\u201d has a value from about 0 to about 12, \n \u201cy\u201d has a value from 0 to about 12, \n \u201cm\u201d has a value from about 3 to about 36 and 1\u2264n+y\u226412, \n wherein the second agent is a zirconium silicate composition comprising ZS-9 and lacks detectable amounts of ZS-8.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.80851
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14060279', '15878120', '14628017', '13939656', '14692287']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8274296129778542
- 35 USC 102 Novelty (BERT): 0.5812739956774841
- Combined Prediction Score: 0.8028140512478172
- Mean Citation Score: 559.3980240000002
- Max Citation Score: 586.7125
- Similarity Product: 390.909367364645

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test