PATENT CLAIM ANALYSIS

Application Number: 15876367
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "054000"]

Abstract:
Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost immune function using a complex carbohydrate pharmaceutical compound alone or in combination with other targeted immunotherapy to increase the efficacy of immunotherapy of cancer.

Claim (Index 14):
A method comprising\n a. obtaining a composition for parenteral or enteral administration comprising: (i) a galactoarabino-rhamnogalacturonate comprising a 1,4-linked galacturonic acid (GalA) comprising methyl galacturonate (MeGalA) residues backbone linked to branched heteropolymers of alternating oligomers of \u03b1-1,2 linked rhamnose and \u03b1-1,4-linked GalA residues, the rhamnose residues carrying a primary branching of oligomers of 1,4-\u03b2-D-galactose residues, 1,5-\u03b1-L-arabinose residues, or combinations thereof, wherein the 1,4- 62  -D-galactose and 1,5-\u03b1-L-arabinose residues are present in a 2:1 to a 3:1 ratio, and wherein the galactoarabino-rhamnogalacturonate has a methyl galacturonate to galacturonic acid ratio ranging from 2:1 to 1:2, and (ii) a therapeutically effective amount of an immune modulatory agent or a vaccine against 4-1BB, 4-1BBL, LAG-3, CD80, CD86, CD134, CD27, CD70, ICOS, ICOS ligand, or combination thereof; and b. administering to a subject in need thereof an effective dose of the composition.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 86.0
- Lexical Diversity: 1.41026
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14029505', '13999389', '15087119', '15478599', '13998197']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7764187859866583
- 35 USC 102 Novelty (BERT): 0.7847842998801473
- Combined Prediction Score: 0.7772553373760072
- Mean Citation Score: 550.234246
- Max Citation Score: 987.4825
- Similarity Product: 935.3663202559948

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test