PATENT CLAIM ANALYSIS

Application Number: 16031503
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "041000"]

Abstract:
There is provided a nucleic acid molecule comprising a nucleotide sequence encoding for a functional factor VIII protein, wherein the portion of the nucleotide sequence encoding for the B domain of the factor VIII protein is between 90 and 111 nucleotides in length and encodes for an amino acid sequence comprising a sequence having at least 85% identity to SEQ ID NO: 4 and which comprises six asparagine residues. Also provided is a functional factor VIII protein, a vector comprising the above nucleic acid molecule, a host cell, a transgenic animal, a method of treating haemophilia, e.g. haemophilia A, and a method for the preparation of a parvoviral gene delivery vector.

Claim (Index 14):
The nucleic acid molecule of any preceding claim, wherein the portions of the nucleotide sequence encoding for the A1, A2, A3, C1 and C2 domains of the factor VIII protein are codon optimised sequences of the wild type sequence.

Metadata:
- Claim Count in Document: 45.0
- Percentile: 95.0
- Lexical Diversity: 1.83582
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14407008', '15254984', '13382953', '14680836', '15764742']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7527254496533625
- 35 USC 102 Novelty (BERT): 0.71874334311427
- Combined Prediction Score: 0.7493272389994533
- Mean Citation Score: 665.3965400000002
- Max Citation Score: 817.72375
- Similarity Product: 772.2858091513068

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test