PATENT CLAIM ANALYSIS

Application Number: 15881409
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "006120"]

Abstract:
Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.

Claim (Index 99):
A method of characterizing a sample from a human subject, the method comprising assaying the sample for amounts of a plurality of different methylated marker DNAs and amounts of at least one control nucleic acid, the method comprising:\n a) combining nucleic acids from the sample in a reaction mixture comprising PCR amplification reagents, wherein the PCR amplification reagents comprise:\n i) a plurality of methylation marker primer pairs for amplifying target regions from a plurality of different methylated marker DNAs selected from the group of ANKRD13B; CHST2; CNNM1; DOCK2; DTX1; FER1L1; FERMT3; FLI1; GRIN2D; JAM3; LRRC4; OPLAH; PDGFD; PKIA; PPP2R5C; QKI; SEP9; SFMBT2; SLC12A8; TBX15; TSPYL5; VAV3; ZDHHC1; ZNF304; ZNF568; and ZNF671; and \n ii) at least one control primer pair for amplifying a target region from at least one control nucleic acid; \n b) exposing the reaction mixture to thermal cycling conditions wherein a plurality of different methylation marker target regions and at least one control nucleic acid target region are amplified; and c) detecting a plurality of different methylated marker target regions and at least one control nucleic acid target region amplified in step b).

Metadata:
- Claim Count in Document: 324.0
- Percentile: 86.0
- Lexical Diversity: 1.33333
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15471337', '15841006', '14966938', '15252966', '14669834']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.608387880334049
- 35 USC 102 Novelty (BERT): 0.5431833531333818
- Combined Prediction Score: 0.6018674276139823
- Mean Citation Score: 348.420024
- Max Citation Score: 412.8369
- Similarity Product: 312.5605829455733

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test