PATENT CLAIM ANALYSIS

Application Number: 16206951
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-04
Patent Classification: ["250", "282000"]

Abstract:
A first mass spectrometer includes a first introduction device configured to select between a reference material and a first portion of an analyte and introduce the selected one of the reference material or the first portion of the analyte to an ion source, the first mass spectrometer being configured to provide third molecular analyte ions to a detector at a first mass resolution of about 30,000 or greater. A system includes the first mass spectrometer and a second mass spectrometer. A method for determining the isotopic composition of an analyte in a sample includes converting a first portion of the analyte to first molecular analyte ions, filtering out second molecular analyte ions, filtering out third molecular analyte ions, detecting two or more of the third molecular analyte ions at a mass resolution of about 30,000 or greater to determine the isotopic composition of at least a portion of the analyte.

Claim (Index 1):
A method for determining the isotopic composition of an analyte in a sample, the method comprising:\n using a first mass spectrometer comprising a single-collector and having a mass-resolution of about 30,000 or greater to measure ratios of ion beams at each cardinal mass of the analyte to produce first molecular analyte ion data; using a second mass spectrometer comprising a multi-collector to measure relative abundances of closely-adjacent ions at different cardinal masses of the analyte to produce second molecular analyte ion data; utilizing the first molecular analyte ion data to identify proportions of isotopologues that contribute to signal intensity at each cardinal mass measured with the second mass spectrometer; and utilizing the proportions of the isotopologues that contribute to the signal intensity at each cardinal mass to compensate for unresolved detected molecular analyte species and calculate an abundance of one or more isotopic species of interest measured with the second mass spectrometer.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 98.0
- Lexical Diversity: 2.80357
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14051392', '13656447', '15616533', '12390305', '14385788']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7343707262080481
- 35 USC 102 Novelty (BERT): 0.6110126025723155
- Combined Prediction Score: 0.7220349138444748
- Mean Citation Score: 430.237524
- Max Citation Score: 576.0606
- Similarity Product: 484.1523223391175

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test