PATENT CLAIM ANALYSIS

Application Number: 16170752
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["514", "407000"]

Abstract:
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.

Claim (Index 5):
The compound of  claim 1  or salt thereof, of formula (IIIa) or (IIIb): wherein: R 1  is selected from the group consisting of substituted or unsubstituted C 2-8  alkyl, substituted or unsubstituted C 1-8  alkoxy, unsubstituted C 1-8  alkylamino, and substituted or unsubstituted C 3-10  heterocyclyl; and R 2  is H, F, Cl, or substituted or unsubstituted C 1-8  alkoxy; or R 1  and R 2  together with the carbon atoms to which they are attached form a non-aromatic carbocyclic ring or a heterocyclic ring; R 3  is H, substituted or unsubstituted C 1-8  alkyl, substituted or unsubstituted C 1-8  alkoxy, or halo; R 4  is H or F; R 5  is H, F, Cl, or \u2014CH 3 ; and R 6  is H, halo, \u2014CN, \u2014CO 2 R a , \u2014CONH 2 , \u2014NH 2 , unsubstituted C 1-8  aminoalkyl, substituted or unsubstituted C 1-8  alkyl, or substituted or unsubstituted C 1-8  alkoxy, wherein R a  is H or substituted or unsubstituted C 1-8  alkyl; or R 5  and R 6  together with the carbon atoms to which they are attached form a carbocyclic ring; each R 8  is independently selected from the group consisting of H, halo, \u2014CN, \u2014OH, oxo, substituted or unsubstituted C 1-8  alkyl, substituted or unsubstituted C 1-8  alkoxy, \u2014NR 20 R 21 , substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, and substituted or unsubstituted heterocyclyl;\n R 20  and R 21  are each independently H or substituted or unsubstituted C 1-8  alkyl; and \n n is 0, 1, 2 or 3.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 97.0
- Lexical Diversity: 1.73333
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13781412', '10260008', '15383788', '11453221', '10533326']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8152319567649441
- 35 USC 102 Novelty (BERT): 0.5524276941474465
- Combined Prediction Score: 0.7889515305031944
- Mean Citation Score: 314.8755920000001
- Max Citation Score: 409.82324
- Similarity Product: 391.69481034631735

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test