PATENT CLAIM ANALYSIS

Application Number: 15897371
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["424", "489000"]

Abstract:
The disclosure provides methods of manufacturing small nanoparticles of degradable polymers.

Claim (Index 9):
A method for preparing polymeric nanoparticles, wherein said method comprises a double emulsion process comprising:\n (a) dissolving a pharmaceutically acceptable PLGA polymer in a first solvent to form a polymer solution and dissolving or dispersing an active pharmaceutical ingredient (API) in a second solvent comprising water; (b) adding a small amount of the second solvent to the polymer solution to form a mixture, wherein the first solvent is not miscible or only partially miscible with the second solvent; (c) emulsifying the mixture by microfluidization to form a first emulsion; (d) emulsifying the first emulsion in a third solvent comprising water and a surfactant to form a second emulsion; and, (e) removing the first solvent to form said nanoparticles, wherein said nanoparticles have an Z average particle size of about 100 nm or less.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 88.0
- Lexical Diversity: 1.09091
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13862128', '15161785', '14148082', '12485406', '13915049']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6588933121086867
- 35 USC 102 Novelty (BERT): 0.4852353896839583
- Combined Prediction Score: 0.6415275198662138
- Mean Citation Score: 202.369438
- Max Citation Score: 203.59595
- Similarity Product: 159.30391005374787

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test