PATENT CLAIM ANALYSIS

Application Number: 16298521
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "317100"]

Abstract:
Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (IA) are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having IA.

Claim (Index 9):
A method of identifying a candidate compound for the treatment of IA, the method comprising:\n providing a test culture comprising one or more  Aspergillus  species; detecting a baseline level of fungal VOCs in the headspace of the culture in the absence of the test compound, wherein the VOCs are selected from the group consisting of camphene, \u03b1-pinene, \u03b2-pinene, limonene, \u03b1-trans-bergamotene, \u03b2-trans-bergamotene, trans-geranylacetone, elixene, alpha-santalene, beta-elemene, acoradien, chamigrene, 1,5,9-trimethyl cyclododecatriene, 9-decene-2-one and beta-sesquiphellandrene, in the subject; contacting the test culture with a test compound; determining a second level of the VOCs in a the test culture; comparing the second level of VOCs to the baseline level; and identifying a test compound that decreases levels of fungal VOCs in the test culture as a candidate compound for the treatment of IA.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.27778
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316062', '14426678', '15023640', '14628125', '13261101']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6048666986260199
- 35 USC 102 Novelty (BERT): 0.6487454360528309
- Combined Prediction Score: 0.6092545723687011
- Mean Citation Score: 408.262416
- Max Citation Score: 777.9191
- Similarity Product: 575.6442837024807

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test