PATENT CLAIM ANALYSIS

Application Number: 15743756
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["530", "387300"]

Abstract:
The present disclosure relates to antibody molecules comprising a binding domain specific to CD22, said binding domain comprising SEQ ID NO: 1, 2, 3, 4, 5 and 6 or 7. The disclosure also extends to pharmaceutical compositions comprising said antibody molecules and use of the antibody molecules/compositions in treatment.

Claim (Index 3):
An antibody molecule comprising a binding domain specific to CD22 wherein the binding domain comprises a heavy chain variable domain (VH) comprising:\n CDRH1 of formula (I): (SEQ ID NO: 1) GX 1 X 2 FSX 3 X 4 X 5 X 6 X 7 X 8 wherein X 1  is F, I or L, X 2  is S or D, X 3  is S, N or G, X 4  is S, Y, L or G, X 5  is Y or absent, X 6  is W, Y or D, X 7  is M or I and X 8  is C or S; CDRH2 of formula (II): (SEQ ID NO: 2) X 9 IX 10 X 11 X 12 X 13 X 14 X 15 X 16 TX 17 YAX 18 WAKG wherein X 9  is C or S, X 10  is Y, D, V or N, X 11  is T, P, I, G, S or A, X 12  is G, S or A, X 13  is S, I or T, X 14  is S, N or absent, X 15  is G, D, S, A or T, X 16  is D, T, S, N, V or G, X 17  is Y, D or A and X 18  is T or S; CDHR3 of formula (III): (SEQ ID NO: 3) X 19 X 20 X 21 X 22 X 23 X 24 X 25 X 26 X 27 X 28 X 29 X 30 X 31 X 32 X 33 L wherein X 19  is A or absent, X 20  is absent, G or Y, X 21  is absent, P or G, X 22  is absent, Y, S, D or E, X 23  is V, G, Y or W, X 24  is G, Y, S or V, X 25  is Y, S, G or N, X 26  is G, A, S or T, X 27  is Y, G or D, X 28  is D, I, Y, W or H, X 29  is L, G, S, Y or K, X 30  is V, Q, C, S, G, T or D, X 31  is Y, A or R, X 32  is L or F, X 33  is N, Y or D, and a light chain variable domain (VL) comprising CDRL1 of formula (IV): (SEQ ID NO: 4) QX 34 SX 35 X 36 X 37 X 38 X 39 X 40 X 41 X 42 LX 43 wherein X 34  is A or S, X 35  is Q or E, X 36  is S, N or T, X 37  is I or V, X 38  is S, Y or G, X 39  is T, S, G or N, X 40  is A, G, N, Y, T or R, X 41  is absent, N or K, X 42  is absent, E or D and X 43  is A or S; CDRL2 of formula (V): (SEQ ID NO: 5) X 44 X 45 SX 46 LX 47 S wherein X 44  is G, Y, L, A or S, X 45  is A, S or T, X 46  is T, R or K and X 47  is A or S; CDRL3 has a formula (VI): (SEQ ID NO: 6) AGYKSX 48 X 49 DX 50 X 51 TT wherein X 48  is D or E, X 49  is S, A or T, X 50  is D or E and X 51  is G, A or S; or CDRL3 of formula (VII): (SEQ ID NO: 7) QX 52 X 53 X 54 X 55 X 56 SX 57 X 58 X 59 X 60 X 61 X 62 X 63 X 64 wherein X 52  is S, I or G, X 53  is Y, H or G, X 54  is Y, D or F, X 55  is G, S or Y, X 56  is T, A or S, X 57  is S, G, V or D, X 58  is G, S, L or absent, X 59  is G, R, S or N, X 60  is S, D or V, X 61  is W, Y or absent, X 62  is A, T, G or absent, X 63  is N or absent, X 64  is A or absent.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 86.0
- Lexical Diversity: 1.46154
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15743764', '15326501', '15627161', '15430998', '13107439']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7535736690134412
- 35 USC 102 Novelty (BERT): 0.6193237764917653
- Combined Prediction Score: 0.7401486797612737
- Mean Citation Score: 451.072982
- Max Citation Score: 608.11847
- Similarity Product: 462.0614363311148

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test