PATENT CLAIM ANALYSIS

Application Number: 15769073
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["506", "016000"]

Abstract:
Provided in the present invention is a method for constructing a high-resolution single cell Hi-C library with a large amount of information, comprising the following steps: Step B: obtain a small amount of fixed chromatin; Step C: digest the fixed chromatin in Step B to obtain fragments of the fixed chromatin; Step D: reconnect the fragments of the fixed chromatin in Step C directly to obtain reconnected fragments of the fixed chromatin; Step E: de-fix the reconnected fragments of the fixed chromatin in Step D to release DNA fragments; Step F: amplify the released DNA fragments in Step E to obtain amplified products; and Step H: construct a sequencing DNA library by using the amplified products as the DNA fragments to be sequenced.

Claim (Index 4):
The method of  claim 1 , wherein a deoxyribonuclease is used in Step C to digest the fixed chromatin.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 2.32203
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10083682', '09844501', '12699508', '14359877', '11373519']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6199270881765069
- 35 USC 102 Novelty (BERT): 0.500283082006255
- Combined Prediction Score: 0.6079626875594818
- Mean Citation Score: 240.546342
- Max Citation Score: 244.95952000000003
- Similarity Product: 175.49506611023904

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test