PATENT CLAIM ANALYSIS

Application Number: 15927327
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["424", "093700"]

Abstract:
The invention is directed to delivering therapeutic agents to the eye for the purpose of treating ophthalmic disorders, diseases and injuries. In particular, the invention is directed to delivering therapeutic agents to the eye for the purpose of treating ophthalmic disorders, diseases and injuries by targeted intranasal administration of the therapeutic agents. The invention is specifically directed to treating disorders, diseases and injuries of the cornea and ocular surface, treating retinal disorders, diseases and injuries and optic nerve disorders, diseases and injuries by targeted intranasal administration of the therapeutic agents.

Claim (Index 18):
A method for treating a back of the eye ophthalmic disorder, disease or injury in a patient in need thereof comprising administering ST266 by targeted intranasal administration, wherein the targeted intranasal administration comprises specifically targeting the nasal mucosa adjacent to the foramina of the cribriform plate located at the superior aspect of the nasal cavity such that the ST266 bypasses the blood-brain barrier by permeating through the foramina into the cranial cavity and is deposited on the optic nerve and in the globe of the eye, wherein the ST266 is comprised of physiological concentrations of VEGF, TGF\u03b22, Angiogenin, PDGF, TIMP-1 and TIMP-2 and wherein the physiologic concentration is \u02dc5.0-16 ng/mL for VEGF, \u02dc3.5-4.5 ng/mL for Angiogenin, \u02dc100-165 pg/mL for PDGF, \u02dc2.5-2.7 ng/mL for TGF\u03b22, \u02dc0.68 \u03bcg/mL for TIMP-1 and \u02dc1.04 \u03bcg/mL for TIMP-2.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 2.94118
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14556300', '14276140', '13374166', '15492446', '14525654']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6604625870343148
- 35 USC 102 Novelty (BERT): 0.5118069418702017
- Combined Prediction Score: 0.6455970225179035
- Mean Citation Score: 188.23888
- Max Citation Score: 256.34558
- Similarity Product: 176.4768767334974

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test