PATENT CLAIM ANALYSIS

Application Number: 15906424
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["544", "280000"]

Abstract:
The invention provides compounds of Formula (I), immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat diseases or disorders associated with Toll-Like Receptor 7 activity.

Claim (Index 2):
The method of  claim 1 , or pharmaceutically acceptable salt thereof, wherein:\n R 1  is \u2014NHR 6  or \u2014NHCHR 6 R 9 ; R 3  is -L 2 C(\u2550O)OR 7 , \u2014C(\u2550O)OL 6 R 12 , \u2014C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 2 R 12 , -L 4 C(\u2550O)OL 5 OH, -L 4 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)L 2 R 12 , -L 2 C(\u2550O)OL 6 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)R 12 , -L 4 C(\u2550O)OL 2 C(\u2550O)R 12 , \u2014CF 2 C(\u2550O)R 7 , \u2014CH\u2550CHC(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 2 C(\u2550O)OL 4 (\u2550O)R 12 , \u2014OL 4 C(\u2550O)OL 2 R 12 , \u2014OL 4 (\u2550O)OL 2 C(\u2550O)R 12  or -L 2 C(\u2550O)OL 3 R 12 ; R 4  is -L 2 C(\u2550O)OR 7 , \u2014C(\u2550O)OL 6 R 12 , \u2014C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 2 R 12 , -L 4 (\u2550O)OL 5 OH, -L 4 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)L 2 R 12 , -L 2 C(\u2550O)OL 6 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)R 12 , -L 4 C(\u2550O)OL 2 C(\u2550O)R 12 , \u2014CF 2 C(\u2550O)R 7 , \u2014CH\u2550CHC(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 2 C(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 4 C(\u2550O)OL 2 R 12 , \u2014OL 4 C(\u2550O)OL 2 C(\u2550O)R 12  or -L 2 C(\u2550O)OL 3 R 12 ; or R 4  is H, and R 3  is -L 2 C(\u2550O)OR 7 , \u2014C(\u2550O)OL 6 R 12 , \u2014C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 2 R 12 , -L 4 C(\u2550O)OL 5 OH, -L 4 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)L 2 R 12 , -L 2 C(\u2550O)OL 6 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 4 (\u2550O)R 12 , -L 4 C(\u2550O)OL 2 C(\u2550O)R 12 , \u2014CF 2 C(\u2550O)R 7 , \u2014CH\u2550CHC(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 2 C(\u2550O)OL 4 (\u2550O)R 12 , \u2014OL 4 C(\u2550O)OL 2 R 12 , \u2014OL 4 C(\u2550O)OL 2 C(\u2550O)R 12  or -L 2 C(\u2550O)OL 3 R 12 ; or R 3  is H, and R 4  is -L 2 C(\u2550O)OR 7 , \u2014C(\u2550O)OL 6 R 12 , \u2014C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 2 R 12 , -L 4 C(\u2550O)OL 5 OH, -L 4 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)L 2 R 12 , -L 2 C(\u2550O)OL 6 R 12 , -L 2 C(\u2550O)OL 4 C(\u2550O)OL 2 R 12 , -L 2 C(\u2550O)OL 4 (\u2550O)R 12 , -L 4 C(\u2550O)OL 2 C(\u2550O)R 12 , \u2014CF 2 C(\u2550O)R 7 , \u2014CH\u2550CHC(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 2 C(\u2550O)OL 4 C(\u2550O)R 12 , \u2014OL 4 (\u2550O)OL 2 R 12 , \u2014OL 4 C(\u2550O)OL 2 C(\u2550O)R 12  or -L 2 C(\u2550O)OL 3 R 12 ; L 1  is \u2014(CH 2 ) m \u2014; L 2  is \u2014(CH 2 ) m \u2014; L 3  is \u2014(CH 2 ) m \u2014; L 4  is \u2014(CH 2 ) m \u2014; L 5  is \u2014(CH 2 ) m \u2014; L 6  is \u2014(CH 2 ) m O(CH 2 ) m \u2014; R 6  is \u2014C 4 -C 6 alkyl; R 7  is \u2014C 1 -C 3 alkyl; R 9  is L 1 OH; each R 11  is independently selected from H or \u2014C 1 -C 3 alkyl; R 12  is\n a) \u2014N(R 11 ) 2 ; \n b) an unsubstituted 5-6 membered heterocycloalkyl having 1 to 2 heteroatoms independently selected from N and O; \n c) a 5-6 membered heterocycloalkyl having 1 to 2 heteroatoms independently selected from N and O substituted with \u2550O; \n d) a 5-6 membered heterocycloalkyl having 1 to 2 heteroatoms independently selected from N and O substituted with C 1 -C 3 alkyl or \u2014C(\u2550O)OR 7 ; \n or \n e) an unsubstituted phenyl; \n and each m is independently selected from 1, 2, 3, and 4.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 88.0
- Lexical Diversity: 1.2
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15307510', '15307525', '10947420', '12310597', '15320887']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8266845589005107
- 35 USC 102 Novelty (BERT): 0.6141621934373628
- Combined Prediction Score: 0.805432322354196
- Mean Citation Score: 437.961316
- Max Citation Score: 558.81177
- Similarity Product: 523.8555244512247

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test