PATENT CLAIM ANALYSIS

Application Number: 16007825
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "401000"]

Abstract:
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders. Also included herein are methods for extending lifespan.

Claim (Index 7):
The method of  claim 1 , wherein the compound is a prodrug, and contacting a senescent cell in the test subject with the prodrug causes the polypeptide expressed from the transgene to convert the prodrug to an active form of the prodrug that is lethal to the cell.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 94.0
- Lexical Diversity: 1.63462
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15981696', '15455684', '15955542', '16007880', '15827539']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8604473571420457
- 35 USC 102 Novelty (BERT): 0.5860687305267542
- Combined Prediction Score: 0.8330094944805165
- Mean Citation Score: 572.9718799999997
- Max Citation Score: 579.3641
- Similarity Product: 398.9161411481321

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test