PATENT CLAIM ANALYSIS

Application Number: 16007853
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "006120"]

Abstract:
Compositions, systems and methods for the diagnosing the risk of acute myocardial infarction are provided. The methods described herein relate to the use of biomarkers, such as gene expression profiles, and analytical tools for providing information to a health care provider or the patient, that is relevant to the cardiovascular health of the patient.

Claim (Index 191):
A method of identifying an individual as being at increased risk of experiencing a myocardial infarction, comprising:\n (a) detecting the level of expression of one or more gene expression products in a blood sample isolated from an individual experiencing a cardiovascular event or suspected of experiencing a cardiovascular event; (b) comparing the level of gene expression in the blood sample to a control or standard; and (c) identifying the individual as being at an increased risk for experiencing a myocardial infarction based on the difference in the level of gene expression between the blood sample and the control or standard, wherein the one or more gene expression products is expressed by one or more genes selected from among HBEGF, NR4A2, NR4A3, EFEMP1, NFKBIA, NLRP3, THBS1, MCAM, RGS1, GABPB1, CXCL2, CCL20, EDN1, CCL3, MGP, VWF, CREM, FN1, PHACTR1, SYTL3, VPS8, SULF1, RNASE1, and combinations thereof.

Metadata:
- Claim Count in Document: 75.0
- Percentile: 94.0
- Lexical Diversity: 1.42857
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14714063', '15313493', '14426430', '13913077', '12745220']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5261505627520862
- 35 USC 102 Novelty (BERT): 0.737974724508348
- Combined Prediction Score: 0.5473329789277124
- Mean Citation Score: 435.4076480000001
- Max Citation Score: 1192.7365
- Similarity Product: 829.8740015425682

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test