PATENT CLAIM ANALYSIS

Application Number: 15747980
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-12
Patent Classification: ["546", "045000"]

Abstract:
There is provided a novel process for the preparation of a compound of formula (I), wherein R 1  is as described in the description, by demethylation of a corresponding O-methyl derivative.

Claim (Index 1):
A process for the preparation of a compound of formula I, or a pharmaceutically acceptable salt thereof; wherein: R 1  represents hydrogen or C 1-12  alkyl, C 2-12  alkenyl, C 2-12  alkynyl or C 3-12  cycloalkyl, (which latter four groups are optionally substituted by one or more halogen atoms or phenyl groups); which process comprises contacting a compound of formula II, or a salt thereof, wherein R 1a  is defined according to R 1 , with a mixture comprising water, a carboxylic acid, a sulfonic acid, and a sulfide compound; wherein the sulfide compound is selected from the group consisting of cyclic sulfur-containing compounds and sulfides of formula III,\n X 1 \u2014S\u2014X 2 \u2003\u2003III \n wherein X 1  and X 2  each independently represents hydrogen, phenyl, \u2014C(O)R 3  or a C 1-12  alkyl group (optionally substituted by one or more groups selected from halogen, \u2014OH, \u2014NH 2 , phenyl, \u2014O\u2014C 1-4  alkyl, \u2014C(O)R 4  and \u2014S(O) m \u2014C 1-4  alkyl); R 3  and R 4  independently represent \u2014OH, \u2014C 1-4  alkyl or \u2014O\u2014C 1-4  alkyl; and m represents from 0 to 2.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 86.0
- Lexical Diversity: 1.24138
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14906776', '15644266', '13686725', '15039681', '14692526']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.754412749153875
- 35 USC 102 Novelty (BERT): 0.4740818077701944
- Combined Prediction Score: 0.726379655015507
- Mean Citation Score: 192.399404
- Max Citation Score: 205.97032
- Similarity Product: 164.74221492290496

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test