PATENT CLAIM ANALYSIS

Application Number: 15877042
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["424", "009320"]

Abstract:
The present application concerns multimodal composite products for imaging, in particular for diagnostic imaging, and optionally for therapy, in particular composite products which are capable of being used as contrast agents, in particular in magnetic resonance imaging (MRI), and/or in imaging techniques such as, for example, in optical imaging, in the optical detection of oxidants, in positron emission tomography (PET), in tomodensitometry (TDM) and/or in ultrasound imaging, and optionally simultaneously for use in therapy. These products are based on a particle comprising or consisting of a portion provided with a contrast agent activity and/or a paramagnetic activity, and a portion provided with a luminescent activity and optionally an oxidant detection activity.

Claim (Index 1):
A method for acquiring images by MRI, optical imaging, optical oxidant detection, PET, TDM or ultrasound imaging, or by a combination of at least two of these techniques, from within a patient or an animal to which a multiplicity of luminescent and paramagnetic particles has been administered, the method comprising excitation of the administered particles and acquisition of at least one signal associated with said particles following excitation, wherein each particle comprises at least two portions, a first portion with a formula X a L b (M p O q ), in which:\n M is at least one element which is capable of associating with oxygen (O) to form an anion; L corresponds to one or more luminescent lanthanide ions; X corresponds to one or more ions which are neutral in terms of luminescence; and p, q, a, and b are values such that the electroneutrality of X a L b (M p O q ) is respected and the fraction of luminescent element, defined by a ratio of b/(b+a), is greater than 10% and less than or equal to 75%; and a second portion with a formula A e X\u2032 f (M\u2032 p\u2032 O q\u2032 ), in which:\n M\u2032 is at least one element which is capable of associating with oxygen (O) to form an anion; \n A corresponds to one or more paramagnetic lanthanide ions; \n X\u2032 is optional and, if present, corresponds to one or more ions which are neutral in terms of paramagnetic properties; and \n p\u2032, q\u2032, e, and f are values such that the electroneutrality of A e X\u2032 f (M\u2032 p\u2032 O q\u2032 ) is respected and the fraction of paramagnetic element, defined by a ratio of e/(e+f), being from 80% to 100%.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 86.0
- Lexical Diversity: 2.01538
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15390106', '11627273', '14492749', '11601011', '14426036']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7097748924205236
- 35 USC 102 Novelty (BERT): 0.4944265806787842
- Combined Prediction Score: 0.6882400612463496
- Mean Citation Score: 201.701188
- Max Citation Score: 210.2953
- Similarity Product: 141.14284281039238

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test