PATENT CLAIM ANALYSIS

Application Number: 16150796
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-06
Patent Classification: ["514", "311000"]

Abstract:
Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

Claim (Index 1):
A compound having formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, N-oxide or rotamer thereof, wherein\n A is a carboxylic acid moiety or a carboxylic acid isostere; \n ring vertices a, b, c and d are independently selected from N, CH and C(R 1 ); \n each R 1  is independently selected from the group consisting of halogen, CN, \u2014SF 5 , C 1-8  alkyl, C 3-8  cycloalkyl, C 2-8  alkenyl, C 2-8  alkynyl, C 1-8  haloalkyl, \u2014OR a , \u2014SR a , \u2014COR a , \u2014NR a R b , and 5- or 6-membered heteroaryl, wherein the alkyl portions of R 1  are optionally further substituted with 1-3 R a ; and optionally, adjacent R 1  members are connected to form an additional 5- or 6-membered ring which is saturated or unsaturated having ring vertices selected from C, O, S and N, wherein the additional 5- or 6-membered ring is optionally substituted with one or two members selected from the group consisting of halogen, hydroxyl, C 1-4  alkyl, C 1-4  alkoxy and C 1-4  haloalkyl; \n the subscript m is an integer of from 0 to 2; \n the subscript n is an integer of from 0 to 3; \n each R 2  and R 3  is independently selected from the group consisting of halogen, CN, C 1-8  alkyl, C 3-8  cycloalkyl, C 2-8  alkenyl, C 2-8  alkynyl, C 1-8  haloalkyl, aryl, \u2014OR a , \u2014NR a R b  and \u2014N(R a )\u2014C 1 -C 4  alkylene-OR b , and wherein the alkyl or aryl portions of R 2  and R 3  are optionally further substituted with 1-3 R a ; \n Ar is a 5- or 6-membered aromatic or heteroaromatic ring that is optionally substituted with from 1 to 5 R 4  substituents independently selected from the group consisting of halogen, CN, \u2014SF 5 , C 1-8  alkyl, C 3-8  cycloalkyl, C 2-8  alkenyl, C 2-8  alkynyl, C 1-8  haloalkyl, C 1-8  hydroxyalkyl, \u2014OR a , \u2014NR a R b , 5- or 6-membered heteroaryl, and 3-, 4-, 5- or 6-membered heterocycloalkane wherein the heteroatoms present as ring vertices of the heteroaryl and heterocycloalkane rings are selected from N, O and S, and wherein the alkyl, cycloalkyl, aryl, heteroaryl and hetereocycloalkane portions of R 4  are optionally further substituted with 1-3 R a ; \n each R a  and R b  is independently selected from the group consisting of hydrogen, hydroxyl, halogen, cyano, C 1-4  alkyl, C 1-4  alkoxy, C 1-4  haloalkyl, C 3-6  cycloalkyl, amino, C 1-8  alkylamino, and di C 1-8  alkylamino, or when attached to a nitrogen atom are optionally combined to form a 4- to 7-membered saturated ring, which is optionally substituted with oxo.

Metadata:
- Claim Count in Document: 31.0
- Percentile: 97.0
- Lexical Diversity: 1.13043
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14557949', '15074965', '15353889', '15794800', '14137479']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8342163041654634
- 35 USC 102 Novelty (BERT): 0.5372749711289099
- Combined Prediction Score: 0.804522170861808
- Mean Citation Score: 349.591138
- Max Citation Score: 382.49023
- Similarity Product: 364.8017038040554

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test