PATENT CLAIM ANALYSIS

Application Number: 15765048
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["514", "279000"]

Abstract:
The invention concerns a compound of the following formula (I) or a pharmaceutically acceptable salt or solvate thereof as well as a pharmaceutical composition containing such a compound, and the use of such a compound as a drug, notably as a DNMT inhibitor, in particular in the treatment of cancer.

Claim (Index 17):
A compound of the following formula (I) or a pharmaceutically acceptable salt or solvate thereof: wherein:\n W is H, \n X 1  and X 2  are, independently of each other, H, (C 1 -C 10 )-alkyl, (C 1 -C 10 )-alkyl-R 2 , (C 2 -C 10 )-alkenyl, (C 2 -C 10 )-alkenyl-R 2 , CONR 3 R 4 , CSNR 3 R 4 , COR 3 , COOR 6 , CN, SOOR 7 , C(NH)NHR 3 , (C 1 -C 10 )-alkyl-(C 5 -C 10 )-aryl or (C 1 -C 10 )-alkyl-(5-12)-membered-heterocycle, \n wherein: \n R 2  is OH, O\u2014(C 1 -C 10 )-alkyl, O\u2014(C 5 -C 10 )-aryl, NO 2 , CN, NR 4 R 5 , (5-12)-membered-heterocycle, (C 5 -C 10 )-aryl, O\u2014((CH 2 ) 2 O) n \u2014OH with n=1-3, CONR 3 R 4 , halogen, COOR 4 , CF 3 , or (C 3 -C 12 )-cycloalkyl, in which (C 5 -C 10 )-aryl and (5-12)-membered-heterocycle are optionally substituted by at least one group selected from NR 4 R 5 , OR 5 , (C 1 -C 10 )-alkyl, halogen and oxo (\u2550O), \n R 3  is H, or a group chosen among (C 1 -C 10 )-alkyl, (C 3 -C 12 )-cycloalkyl, (C 2 -C 10 )-alkenyl, (C 5 -C 10 )-aryl and a (5-12)-membered-heteroaryl, said group being optionally substituted by at least one group selected from halogen, CN, NR 4 R 5 , mono(C 1 -C 6 )alkyl-amino, di-(C 1 -C 6 )-alkyl-amino, NO 2 , CONR 4 R 5 , COOR 4 , CF 3 , OR 4  and (C 1 -C 10 )-alkyl-R 8 , \n R 4  is H or (C 1 -C 10 )-alkyl, \n R 5  is H, (C 1 -C 10 )-alkyl, (C 5 -C 10 )-aryl or (5-12)-membered-heterocycle, \n R 6  is H, (C 1 -C 10 )-alkyl, (C 5 -C 10 )-aryl or (C 1 -C 10 )-alkyl-R 2 , \n R 7  is (C 1 -C 10 )-alkyl, (C 2 -C 10 )-alkenyl, (C 5 -C 10 )-aryl or a (5-12)-membered-heterocycle, in which the fragments (C 5 -C 10 )-aryl and (5-12)-membered-heterocycle are optionally substituted by at least one group selected from halogen, CN, NR 4 R 5 , mono(C 1 -C 6 )alkyl-amino, di-(C 1 -C 6 )-alkyl-amino, NO 2 , CONR 3 R 4 , COOR 4 , CF 3  and OR 4 , \n R 8  is H, (C 1 -C 10 )-alkyl, (C 5 -C 10 )-aryl or (5-12)-membered-heterocycle, in which (C 5 -C 10 )-aryl and (5-12)-membered-heterocycle are optionally substituted by at least one group selected from NR 4 R 5 , OR 5 , (C 1 -C 10 )-alkyl, halogen and oxo, \n R 1  is hydrogen, (C 1 -C 6 )-alkyl, COR 6  or SOOR 9  with R 9  being a (C 1 -C 6 )-alkyl group optionally substituted by at least one halogen, \n with the proviso that at least one of X 1  and X 2  is not H or (C 1 -C 10 )-alkyl.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 90.0
- Lexical Diversity: 1.55556
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11766171', '15566872', '14128516', '15023209', '14943931']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.776612229675301
- 35 USC 102 Novelty (BERT): 0.5209406187235228
- Combined Prediction Score: 0.7510450685801232
- Mean Citation Score: 293.8900359999999
- Max Citation Score: 300.67657
- Similarity Product: 224.22693851720751

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test