PATENT CLAIM ANALYSIS

Application Number: 16125896
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2018-12
Patent Classification: ["514", "335000"]

Abstract:
Disclosed are a p-toluenesulfonate of a MEK kinase inhibitor, and a crystal form thereof and a preparation method thereof. Specifically disclosed are a 2-((2-fluorine-4-iodophenyl)amino)-1-methyl-4-((6-methylpyridine-3-group)oxygroup)-6-carbonyl-1,6-dihydropyridine-3-formamide p-toluenesulfonate (a compound represented by formula (I)), a crystal form I, and a preparation method thereof. The obtained crystal form I of the compound of formula (I) has good crystal form stability and chemical stability, and the crystallization solvent used has low toxicity and low residue, and is more suitable for use in clinical treatment.

Claim (Index 11):
A method of treating melanoma in a subject in need thereof, the method comprising administering to the subject the 2-((2-fluoro-4-iodophenyl)amino)-1-methyl-4-((6-methylpyridin-3-yl)oxy)-6-oxo-1,6-dihydropyridine-3-carboxamide p-toluenesulfonate of formula (I) according to  claim 1 .

Metadata:
- Claim Count in Document: 15.0
- Percentile: 97.0
- Lexical Diversity: 2.01887
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15559516', '15030125', '15719138', '13796437', '13801753']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7319029946313753
- 35 USC 102 Novelty (BERT): 0.5884254911568056
- Combined Prediction Score: 0.7175552442839184
- Mean Citation Score: 324.5129
- Max Citation Score: 485.1174
- Similarity Product: 470.45201877590415

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test