PATENT CLAIM ANALYSIS

Application Number: 16104504
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["435", "006120"]

Abstract:
A heating mechanism for use in DNA applications such as DNA amplification, extraction and sterilization is provided. Nanoparticles having photo-thermal properties are put in contact with a reaction mixture and irradiated with an activation light beam to activate these photo-thermal properties, thereby releasing heat. Nanoparticles of several types may be used. Use of the same nanoparticles or of different one to monitor the reaction using a different light beam is also presented.

Claim (Index 27):
A method of amplifying a nucleic acid molecule with a polymerase chain reaction (PCR) or a loop-mediated isothermal amplification (LAMP), through bulk heating a biological enzymatic reaction mixture in solution containing\n a nucleic acid template comprising a reverse transcribed nucleic acid, a polymerase enzyme, and chemically modified nanoparticles comprising nanorods of metal, metallic coated organic nanotubes, or a combination thereof, having photo-thermal properties, to promote said LAMP, comprising:\n a) irradiating said chemically modified nanoparticles with an activation light beam from a continuous wave laser to provide excitation for a period of time to activate said photo-thermal properties of said chemically modified nanoparticles, such that said chemically modified nanoparticles release heat sufficient to provide said heating to the whole reaction mixture in solution and promote said PCR or said LAMP.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 96.0
- Lexical Diversity: 1.36842
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15720196', '13943312', '14375946', '15175237', '10361481']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5546707292593352
- 35 USC 102 Novelty (BERT): 0.5894090898397458
- Combined Prediction Score: 0.5581445653173763
- Mean Citation Score: 302.978108
- Max Citation Score: 480.01874
- Similarity Product: 468.1812817854535

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test