PATENT CLAIM ANALYSIS

Application Number: 16110440
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "023000"]

Abstract:
Disclosed herein are compositions containing an opioid antagonist such as naloxone and one or more pharmaceutically acceptable excipients. The compositions may be used for intranasal delivery of Naloxone for the treatment of, for example, opioid overdose in an individual in need thereof. Also disclosed are methods of making compositions containing Naloxone, and devices for nasal delivery of naloxone compositions.

Claim (Index 1):
A method for treating an opioid overdose in an individual in need thereof, the method comprising spraying about 100 \u03bcL of an aqueous solution into a nostril of the individual, wherein the aqueous solution comprises:\n about 15 mg/mL to about 30 mg/mL of naloxone or a pharmaceutically acceptable salt thereof, and (ii) about 5 mM and about 15 mM of ethylene diamine tetraacetic acid or a pharmaceutically acceptable salt thereof, wherein the aqueous solution is capable of remaining substantially free of a naloxone related substance for at least 6 months when stored in a sealed package, and wherein the naloxone related substance comprises 10-\u03b1-hydroxynaloxone, oxymorphone, noroxymorphone, 10-\u03b2-hydroxynaloxone, 7,8-didehydronaloxone, 2,2\u2032-bisnaloxone, 3-O-allynlnaloxone, or a combination of two or more thereof.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 96.0
- Lexical Diversity: 1.51163
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14576357', '14882857', '14950707', '15335145', '14659472']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7889549808603245
- 35 USC 102 Novelty (BERT): 0.5460147579514747
- Combined Prediction Score: 0.7646609585694395
- Mean Citation Score: 371.244514
- Max Citation Score: 434.96957
- Similarity Product: 265.90428345950187

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test