PATENT CLAIM ANALYSIS

Application Number: 16024283
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "649000"]

Abstract:
Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

Claim (Index 31):
The method of  claim 30  for preparing the isolated compound of formula (I), or pharmaceutically acceptable salt thereof, wherein\n R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10  are independently H; \n R 11  is methyl; \n R 12  and R 13  are independently methyl; \n R 14  is ethyl; \n n=1; and \n * is in the R configuration in greater than 99.5% e.e., or * is in the S configuration in greater than 99.5% e.e.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 94.0
- Lexical Diversity: 1.39474
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15245935', '14190702', '13759382', '12530214', '14465470']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7611632407630601
- 35 USC 102 Novelty (BERT): 0.6309360772469602
- Combined Prediction Score: 0.7481405244114501
- Mean Citation Score: 303.701184
- Max Citation Score: 774.36896
- Similarity Product: 509.1116116851807

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test