PATENT CLAIM ANALYSIS

Application Number: 15942333
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "211080"]

Abstract:
Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibitng HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

Claim (Index 26):
The compound of  claim 25 , wherein D is a 5-10 membered heteroaryl, having 1-4 heteroatoms selected from O, S, and N; and optionally substituted with one, two, three or four substituents, wherein two of the substituents attached to different atoms are taken together with the atom to which each is attached to form a bicyclic or tricyclic, wherein said bicyclic or tricyclic is optionally substituted; or the 5-10 membered heteroaryl is fused with a ring selected from the group consisting of 5 or 6 membered heteroaryl, 5-10 membered heterocyclyl, C 6  aryl and C 3-8  cycloalkyl, wherein the 5-10 membered heteroaryl of D and the fused ring are optionally substituted, wherein said fused ring forms an optionally substituted bicyclic or tricyclic system.

Metadata:
- Claim Count in Document: 104.0
- Percentile: 90.0
- Lexical Diversity: 1.71429
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15942321', '15698788', '13266976', '15852639', '14428546']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8073759579842986
- 35 USC 102 Novelty (BERT): 0.5314506225511973
- Combined Prediction Score: 0.7797834244409885
- Mean Citation Score: 281.45004400000005
- Max Citation Score: 362.283
- Similarity Product: 252.6644467331171

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test