PATENT CLAIM ANALYSIS

Application Number: 16073469
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["514", "058000"]

Abstract:
A complexation process between a cyclodextrin and active pharmaceutical ingredients is disclosed, and comprises a process for preparing a complex of at least one cyclodextrin and at least one active pharmaceutical ingredient comprising the steps of a. Preparing a first solution (solution A) comprising at least one cyclodextrin and at least one solvent; b. Preparing a second solution (solution B) comprising at least one dissolved, partially dissolved or suspended API; c. Mixing said solution A and solution B by means of a microfludization system to produce a solution and/or suspension of at least one of said complex; d. Isolating said solution and/or suspension and/or optionally drying it; and e. Optionally collecting a powdered form of the complex.   The described process has high throughput with higher yields of complexation in less time than prior art methods. The complexes obtained by the invention are characterized by having enhanced dissolution and/or bioavailability of the active pharmaceutical ingredient in body fluids.

Claim (Index 29):
A process according to any preceding claim, wherein the process temperature ranges from 0\u00b0 C. to 90\u00b0 C.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 95.0
- Lexical Diversity: 1.95455
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10499338', '14427244', '11489466', '14399582', '11144965']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7547692378647146
- 35 USC 102 Novelty (BERT): 0.5172457668324192
- Combined Prediction Score: 0.7310168907614851
- Mean Citation Score: 180.62844
- Max Citation Score: 190.79808
- Similarity Product: 95.246239737854

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test