PATENT CLAIM ANALYSIS

Application Number: 16445120
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-10
Patent Classification: ["514", "04400A"]

Abstract:
The present invention relates to the 14-3-3 protein which is a non-alcoholic fatty liver regulating factor. According to the present invention, two isoform proteins of 14-3-3, i.e., 14-3-3β and 14-3-3γ, are different regulating factors for regulating the transcriptional activity of PPARγ 2 . 14-3-3β increases the transcriptional activity of PPARγ 2  by binding to PPARγ 2 , on the other hand, 14-3-3γ plays a role in decreasing the transcriptional activity of PPARγ 2 . Thus, 14-3-3β and 14-3-3γ, which are PPARγ 2  regulating factors, are proteins that play a vital role in lipid metabolism, and may be used as a target for the prevention or treatment of fatty liver.

Claim (Index 2):
The method of  claim 1 , wherein measurement of the change in binding of the 14-3-3\u03b2 proteins to PPAR\u03b3 2  proteins by the candidate material is performed by measuring a change in binding of the 14-3-3\u03b2 proteins to the Ser273 residue of PPAR\u03b32.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 100.0
- Lexical Diversity: 2.0339
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15747320', '12708803', '15042244', '13766839', '11262645']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7161907193266114
- 35 USC 102 Novelty (BERT): 0.5740884421359124
- Combined Prediction Score: 0.7019804916075415
- Mean Citation Score: 268.34789
- Max Citation Score: 539.71313
- Similarity Product: 310.8146248713678

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test