PATENT CLAIM ANALYSIS

Application Number: 15752079
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "586000"]

Abstract:
The present invention relates to a novel use of a thiourea derivative and, more specifically, to a pharmaceutical composition for preventing or treating autoimmune diseases comprising a thiourea derivative as an active ingredient. The thiourea derivative according to the present invention can inhibit the transcription of inflammatory genes such as TNF-α, IL-1β, NOS2 and IL-6, and also can inhibit the activity or production of Th17 and increase the activity or production of a regulatory T cell (Treg). Thus, it is expected that the thiourea derivative may be usefully used in a pharmaceutical composition, a health food composition, etc. for the prevention, improvement or treatment of various autoimmune diseases including rheumatoid arthritis.

Claim (Index 5):
The method of  claim 1 , wherein the compound inhibits the expression of a TNF-\u03b1, NOS2, IL-1\u03b2 or IL-6 gene.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 88.0
- Lexical Diversity: 1.75
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13516635', '11104422', '12548083', '13791314', '13635874']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7864672245010647
- 35 USC 102 Novelty (BERT): 0.50672881955804
- Combined Prediction Score: 0.7584933840067623
- Mean Citation Score: 249.945416
- Max Citation Score: 260.5172
- Similarity Product: 181.1419370594263

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test