PATENT CLAIM ANALYSIS

Application Number: 15770138
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "394000"]

Abstract:
The invention provides a pharmaceutical composition for injection comprising a NL-101 type compound and a preparation method thereof. The composition uses the NL-101 type compound as an active pharmaceutical ingredient, and the stability of the NL-101 type compound is improved by adding a chloride-containing stabilizing agent or using a co-solvent containing hydrochloric acid, so that the formulation can be stably produced and meet the requirements for clinical safe use.

Claim (Index 2):
The pharmaceutical composition according to  claim 1 , characterized in that\n m is selected from 5, 6, 7 or 8; Z is absent or selected from CH 2 , O, CO, NH, SO 2 , OC(O), C(O)O, C(O)S, NHC(O), C(O)NH, OC(O)NH, NHC(O)O, or NHC(O)S; X 1  and X 2  are independently halogen; and Q is 9-10 membered aryl or heteroaryl; more preferably, Z is absent or selected from CH 2 , O, CO, NH, SO 2 , NHC(O), or C(O)NH, still more preferably, the compound of formula (I) is represented by the following formula (II): wherein R 1  and R 2  are each independently selected from H, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, halogen, \u2014C\u2550NH, amine, cyano, hydroxy, or alkoxy.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 91.0
- Lexical Diversity: 1.43137
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14345562', '13746999', '12762025', '14538464', '14030692']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.773141753126512
- 35 USC 102 Novelty (BERT): 0.5042384075603977
- Combined Prediction Score: 0.7462514185699006
- Mean Citation Score: 226.71752
- Max Citation Score: 266.564
- Similarity Product: 202.2755237238408

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test