PATENT CLAIM ANALYSIS

Application Number: 15767945
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "064000"]

Abstract:
The present invention provides a urea peptidomimetic boronic compound and pharmaceutical compositions thereof, their preparative methods and uses. The compounds are represented by the following formula (1).

Claim (Index 13):
The compound or a pharmaceutically acceptable salt or solvate thereof of  claim 1 , wherein said compound is selected from the group consisting of:\n (28) N-L-phenylalanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (37) N-(1-oxo-1,2,3,4-dihydroisoquinolin-2-ylformyl)-L-phenylalanyl-L-leucine borate; (38) N-L-phenylalanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroquinoline-urea; (39) N-L-phenylalanyl-L-leucine borate-N\u2032-1-methyl-1,2,3,4-tetrahydroisoquinoline-urea; (40) N-L-leucyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (41) N-L-alanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (42) N-L-valyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (43) N-L-naphthylalanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (44) N-L-isoleucyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (45) N-L-tryptophanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (46) N-L-phenylalanyl-L-leucine borate-N\u2032-7-nitro-1,2,3,4-tetrahydroisoquinoline-urea; (47) N-L-homophenylalanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (48) N-L-4-nitro-phenylalanyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (49) N-L-glutamyl-L-leucine borate-N\u2032-1,2,3,4-tetrahydroisoquinoline-urea; (50) N-L-phenylalanyl-L-leucine borate-N\u2032-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-urea; (51) N-L-phenylalanyl-L-leucine borate-N\u2032-7-methoxy-1,2,3,4-tetrahydroisoquinoline-urea; (52) N-L-phenylalanyl-L-leucine borate-N\u2032-6-methoxy-1,2,3,4-tetrahydroisoquinoline-urea; (53) N-L-phenylalanyl-L-leucine borate-N\u2032-8-methoxy-1,2,3,4-tetrahydroisoquinoline-urea; (54) N-L-phenylalanyl-L-leucine borate-N\u2032-5-methoxy-1,2,3,4-tetrahydroisoquinoline-urea; and (55) N-L-phenylalanyl-L-leucine borate-N\u2032-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-urea.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 91.0
- Lexical Diversity: 1.10345
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13379142', '16300162', '14567480', '14734233', '13582678']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7640358693142535
- 35 USC 102 Novelty (BERT): 0.496945065272772
- Combined Prediction Score: 0.7373267889101054
- Mean Citation Score: 214.68997
- Max Citation Score: 237.31741
- Similarity Product: 185.4947276795613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test