PATENT CLAIM ANALYSIS

Application Number: 15906712
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["514", "230200"]

Abstract:
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R 1 -R 4  are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X 3  or P2X 2/3  receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.

Claim (Index 5):
A compound according to  claim 1 , wherein R 1  is:\n optionally substituted heteroaryl; heteroaryl substituted with one or more halogen, C 1  to C 6  alkyl, C 3  to C 6  cycloalkyl, C 3  to C 6  cycloalkyl-C 1  to C 6  alkyl, C 1  to C 6  hydroxyalkyl, C 1  to C 6  alkoxy, C 1  or C 6  alkyl containing 1 to 3 fluorine atoms, or CH 2 CONH 2 ; oxadiazole, pyrazole, thiophene, or isoxazole; oxadiazole substituted with one or more C 1  to C 6  alkyl, pyrazole substituted with one or more C 1  to C 6  alkyl, pyrazole substituted with one or more C 3  to C 6  cycloalkyl-C 1  to C 6  alkyl, pyrazole substituted with one or more C 1  to C 6  alkyl containing 1 to 3 fluorine atoms, pyrazole substituted with one or more CH 2 CONH 2  groups, thiophene substituted with one or more C 1  to C 6  alkyl, or isoxazole substituted with one or more C 1  to C 6  alkyl; oxadiazole substituted with one C 1  to C 6  alkyl, pyrazole substituted with one C 1  to C 6  alkyl, pyrazole substituted with one C 3  to C 6  cycloalkyl-C 1  to C 6  alkyl, pyrazole substituted with one C 1  to C 6  alkyl containing 1 fluorine atom, pyrazole substituted with one CH 2 CONH 2  group, thiophene substituted with one C 1  to C 6  alkyl, or isoxazole substituted with one or two C 1  to C 6  alkyl; oxadiazole substituted with one ethyl, pyrazole substituted with one CH 3  or CH 2 CH 3 , pyrazole substituted with one \u2014CH 2 -cyclopropyl, pyrazole substituted with one CH 2 CH 2 F, pyrazole substituted with one CH 2 CONH 2  group, thiophene substituted with one CH 3 , or isoxazole substituted with two CH 3 ; or 2-ethyl-1,3,4-oxadiazole, 1-methyl-pyrazole, 1-ethyl-pyrazole, 1-cyclopropylmethane-pyrazole, 1-fluoroethane-pyrazole, 1-carboxamidomethyl-pyrazole, 2-methyl-thiophene, or 3,5-dimethyl-isoxazole.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.69811
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15105526', '15184800', '15876810', '12337683', '12142846']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8366205831255314
- 35 USC 102 Novelty (BERT): 0.6198295279693136
- Combined Prediction Score: 0.8149414776099096
- Mean Citation Score: 481.92710199999993
- Max Citation Score: 577.50775
- Similarity Product: 521.704497310996

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test