PATENT CLAIM ANALYSIS

Application Number: 15878277
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["382", "128000"]

Abstract:
A system for quantitative detection and analysis of the interactions of molecules with molecular receptors on the surfaces of biological cells based on detecting a mechanical deformation in the membrane of a cell associated with the molecular interactions, which works for both large and small molecules. The mechanical deformation can be detected with high precision in real time from an optical image of the cell with a differential detection method. The system can be also used to detect the electrical activities, such as ion channel opening and closing, as well as action potential propagation in neuronal cells.

Claim (Index 5):
The system of  claim 3  wherein the biological object is a cell and the image processor operates to measure the plurality of movements of the edge of the biological object by: detecting a cell edge from an optical image of the cell; selecting a region of interest (ROI) at a location of the cell edge; dividing the ROI into two equal halves, wherein one half is inside of the cell, and wherein the second half falls outside of the cell; and determining the edge movement by computing (A\u2212B)/(A+B), where A and B are the intensities of the two halves of the image.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.58462
- Patent Class: 382.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14968331', '12749056', '15223365', '14069696', '12321360']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2443049018952917
- 35 USC 102 Novelty (BERT): 0.6395381351352851
- Combined Prediction Score: 0.283828225219291
- Mean Citation Score: 253.12546
- Max Citation Score: 604.23505
- Similarity Product: 545.3025605162799

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test