PATENT CLAIM ANALYSIS

Application Number: 15890028
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "006110"]

Abstract:
A sequencing method comprising: (i) combining a template nucleic acid having a first optical detection label at the end with a primer to obtain a first complex; (ii) imaging the first complex to obtain a first image; (iii) mixing the first complex, polymerase, and one or more of nucleotides with a optical detection label to obtain an extension product by polymerization reaction; (iv) imaging the extension product to obtain a second image; (v) removing the cleavable group of the nucleotides with the optical detection label from the extension product to obtain a second complex; (vi) repeating the above steps (ii) to (v) once or more times to determine the template nucleic acid sequence. The sequencing method can achieve single molecule sequencing by capturing template nucleic acids through primers.

Claim (Index 19):
An apparatus according to  claim 18 , wherein\n the first correction is performed based on the first image and the second image in the same cycle of reaction, and the second correction is performed based on between the first images or between the second images in the adjacent cycle of reaction, wherein entering the first imaging module, the synthesizing module, the second imaging module and the cleaving module in turn once is defined as a cycle of reaction.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 88.0
- Lexical Diversity: 2.16901
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12618991', '12114163', '12559902', '15654406', '12553478']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6431217980382056
- 35 USC 102 Novelty (BERT): 0.500518201956321
- Combined Prediction Score: 0.6288614384300172
- Mean Citation Score: 252.653482
- Max Citation Score: 259.30356
- Similarity Product: 186.5371976907134

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test