PATENT CLAIM ANALYSIS

Application Number: 15755660
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["514", "291000"]

Abstract:
It is an object of the present invention to provide a pharmaceutical composition, which can suppress a reduction in the content of an active ingredient caused by oxidation or decomposition of rapamycin or a derivative thereof, can ensure long-term stability, and has high safety. In the present invention, the inventors have found that a tocopherol derivative and an ascorbic acid fatty acid ester are used in combination in a pharmaceutical formulation comprising rapamycin or a derivative thereof, so that oxidation or decomposition of the rapamycin or a derivative thereof can be suppressed, thereby completing the present invention. The rapamycin or a derivative thereof, and the tocopherol derivative and the ascorbic acid fatty acid ester are preferably in the form of a solid mixture produced by preparing a solution containing these components and then removing the solvent from the solution.

Claim (Index 2):
The pharmaceutical composition according to  claim 1 , which is produced by preparing a solution containing (A) rapamycin or a derivative thereof, and (B) a tocopherol derivative and (C) an ascorbic acid fatty acid ester, and then removing the solvent from the solution.

Metadata:
- Claim Count in Document: 40.0
- Percentile: 88.0
- Lexical Diversity: 2.0411
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15747604', '15445670', '13789473', '14780124', '12943729']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7748624397590661
- 35 USC 102 Novelty (BERT): 0.5081866859527073
- Combined Prediction Score: 0.7481948643784302
- Mean Citation Score: 228.449612
- Max Citation Score: 282.31985
- Similarity Product: 218.48399227420387

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test