PATENT CLAIM ANALYSIS

Application Number: 15945549
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "118000"]

Abstract:
The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.

Claim (Index 19):
The process of  claim 18 , wherein the amino acid sequence of said engineered polypeptide having transaminase activity further comprises one or more residue differences as compared to SEQ ID NO:2, selected from: X5K, X33L, X36C, X41C/F/K/M/N/R, X42A/G, X44Q, X48D/E/G/K/T, X49T, X51K, X54P, X55L, X76S, X108V, X117G, X122F/Q, X148Q, X150A/F, X152S/T, X155A/I/K/L/T/V, X156Q/R/S, X160P, X164P, X165N, X182T, X215G/H/L, X218M, X241R, X267V, X270T, X273H, X325M, and X328I.

Metadata:
- Claim Count in Document: 101.0
- Percentile: 91.0
- Lexical Diversity: 1.66667
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15443792', '14768408', '14342713', '15449677', '14799180']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6999314135164021
- 35 USC 102 Novelty (BERT): 0.698544105273895
- Combined Prediction Score: 0.6997926826921514
- Mean Citation Score: 534.0153799999998
- Max Citation Score: 735.4903
- Similarity Product: 726.9504456272244

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test