PATENT CLAIM ANALYSIS

Application Number: 15763695
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["435", "235100"]

Abstract:
Embodiments of the disclosure concern systems, methods, and/or compositions for cultivation of mammalian viruses, including at least human  noroviruses  and  sapoviruses  within the Caliciviridae family of viruses. The ex vivo culture systems include intestinal enteroids in combination with bile or a functionally active fraction or component thereof. In specific embodiments, the culture system is utilized to test inactivation compounds for therapeutic or environmental efficacy and to test contaminated comestibles and/or environmental entities for determination of the presence of infectious virus. Furthermore, antiviral compositions may be tested using systems of the disclosure, including drugs, small molecule inhibitors, and biologies such as neutralizing monoclonal antibodies.

Claim (Index 11):
A method of culturing a virus of the Caliciviridae family, comprising the step of subjecting the virus to the system of any of  claims 1 - 10  under suitable conditions.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 90.0
- Lexical Diversity: 1.4557
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15317002', '14946324', '14124499', '13023363', '13269326']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.54857582216616
- 35 USC 102 Novelty (BERT): 0.5068255098372422
- Combined Prediction Score: 0.5444007909332682
- Mean Citation Score: 245.37455
- Max Citation Score: 257.35062
- Similarity Product: 181.47442721595883

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test