PATENT CLAIM ANALYSIS

Application Number: 16045848
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "134100"]

Abstract:
A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.

Claim (Index 1):
A method of treating a TNF\u03b1-associated medical condition in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of plant cells comprising a chimeric polypeptide specifically binding TNF\u03b1 comprising:\n (i) a first domain which comprises a TNF\u03b1 binding domain of a TNF receptor, and \n (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the carboxy terminus of said first domain is translationally fused to the N-terminus of said second domain, thereby treating the TNF\u03b1-associated medical condition in the subject, wherein said TNF\u03b1-associated medical condition is an inflammatory bowel disease.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 95.0
- Lexical Diversity: 1.74419
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14849963', '14773349', '15849771', '13588752', '12636013']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7612030302972539
- 35 USC 102 Novelty (BERT): 0.6568520799049266
- Combined Prediction Score: 0.7507679352580212
- Mean Citation Score: 426.775254
- Max Citation Score: 693.56244
- Similarity Product: 604.3020163651802

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test