PATENT CLAIM ANALYSIS

Application Number: 15952452
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["435", "006120"]

Abstract:
The invention provides methods for isolating RNA from whole urine and urine fractions for the diagnosis of prostate cancer and/or benign prostate hyperplasia. An exemplary method for diagnosing prostate cancer in an individual, said method comprises: (a) determining the amount of RNA encoding one or more diagnostic genes in the soluble urine fraction of a urine sample obtained from said individual; (b) comparing the amount of said RNA to a reference value for said one or more diagnostic genes, wherein said reference value is derived from the amount of RNA encoding said one or more diagnostic genes in one or more individuals that do not have prostate cancer; and (c) diagnosing said individual as having prostate cancer when the amount of said RNA is greater than said reference value.

Claim (Index 38):
The method of  claim 27 , wherein the soluble urine fraction produced by the ultrafiltration is cell-free.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 91.0
- Lexical Diversity: 2.1194
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13997868', '15593921', '12973747', '15130039', '14754434']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.652195315271328
- 35 USC 102 Novelty (BERT): 0.5812642254099277
- Combined Prediction Score: 0.645102206285188
- Mean Citation Score: 405.329496
- Max Citation Score: 520.5163
- Similarity Product: 379.4264600219609

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test