PATENT CLAIM ANALYSIS

Application Number: 16041646
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-02
Patent Classification: ["315", "307000"]

Abstract:
The technology relates in part to methods and compositions for ex vivo proliferation and expansion of epithelial cells.

Claim (Index 1):
A method for proliferating epithelial cells ex vivo, comprising:\n expanding the number of cells in an originating epithelial cell population obtained from a human under defined xeno-free feeder-free expansion culture conditions, thereby generating an expanded epithelial cell population, wherein: the expansion culture conditions comprise i) one or more agents that activate telomerase reverse transcriptase in the population and/or inhibit transforming growth factor beta (TGF-beta) signaling in the population, ii) albumin or a functionally equivalent protein having an amino acid sequence that is at least 95% identical to SEQ ID NO:1 or SEQ ID NO:2, and iii) a defined xeno-free base medium.

Metadata:
- Claim Count in Document: 63.0
- Percentile: 95.0
- Lexical Diversity: 1.05556
- Patent Class: 315.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15258751', '15685853', '15296831', '15296920', '15722327']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8413344013653786
- 35 USC 102 Novelty (BERT): 0.7608415300967446
- Combined Prediction Score: 0.8332851142385151
- Mean Citation Score: 854.0567619999997
- Max Citation Score: 987.98376
- Similarity Product: 873.6724425735713

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test