PATENT CLAIM ANALYSIS

Application Number: 16067830
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-05
Patent Classification: ["514", "231500"]

Abstract:
The present invention relates to 5-substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (Ib), to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients.

Claim (Index 4):
The compound according to  claim 1 , where the compound of general formula (I) is a compound of general formula (Ib), in which\n R 1  represents a group: wherein * indicates the point of attachment of said group with the rest of the molecule; R 2  represents \u2014N-methyl-(2,2-dimethylpropyl), propan-2-yloxy, cyclopent-1-en-1-yl, 6-membered heterocycloalkyl, phenyl, heteroaryl, \u2014(CO)O-methyl, \u2014N\u2550(SO)diethyl, \u2014N\u2550(SO)(CH 2 ) 4 , \u2014(PO)(O-ethyl)methyl, \u2014(PO)(O-(2-methylpropyl))methyl or \u2014(PO)(methyl) 2 ,\n wherein each 6-membered heterocycloalkyl, phenyl or heteroaryl is optionally substituted, one or more times, independently from each other, with halogen, OH, \u2014CN, \u2014NR 7 R 8 , C 1 -C 4 -alkyl, hydroxymethyl, phenyl-CH 2 \u2014, methoxymethyl, C 1 -C 4 -alkoxy, 6-membered heterocycloalkyl, \u2014(CO)OR 7 , \u2014(CO)NR 7 R 8 , \u2014(SO 2 )R 9 , \u2014(SO)R 9 ,\n \u2014SR 9 , \u2014NR 7 (SO 2 )R 9 , or \n \n wherein two substituents of said phenyl group attached to two adjacent phenyl ring atoms are linked to one another to jointly form an ethylenedioxy group; \n R 4  represents methyl; R 5  represents methyl; R 7 , R 8  represent, independently from each other, hydrogen, C 1 -C 5 -alkyl, cyclopropyl, phenyl or unsubstituted phenyl-CH 2 \u2014, which phenyl is optionally substituted, one or more times, with halogen; or R 7  and R 8  together represent a 5-membered cyclic amine group R 9  represents methyl or ethyl; R 10  represents methyl or ethyl; or R 9  and R 10  together, in case of \u2014N\u2550(SO)R 9 R 10  group, represent a tetramethylene group; or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of same.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 95.0
- Lexical Diversity: 1.72
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15159548', '15501079', '11424751', '11529992', '13325751']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7746101469053999
- 35 USC 102 Novelty (BERT): 0.5850444649339449
- Combined Prediction Score: 0.7556535787082543
- Mean Citation Score: 367.023574
- Max Citation Score: 514.3403
- Similarity Product: 379.8448483059764

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test