PATENT CLAIM ANALYSIS

Application Number: 16186769
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "252010"]

Abstract:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

Claim (Index 1):
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein: n is selected from 1, 2 and 3; p is selected from 0, 1 and 2; each occurrence of A is independently selected from \u2014CH\u2550 and \u2014N\u2550, provided that at least one A is \u2014CH\u2550; M is selected from \u2014O\u2014, \u2014S\u2014, and \u2014CR a R b \u2014, each of R a  and R b  is independently selected from H, halogen, \u2014OH and \u2014C 1-8  alkyl; or alternatively, R a  and R b  together with the carbon to which they are attached form a C 3-4  carbocyclic ring, optionally substituted with 1-2 substituents independently selected from halogen and C 1-4  alkyl; R 1  is selected from:\n (1) aryl, and \n (2) heterocyclyl; \n wherein the aryl of (1) is optionally substituted with 1-3 substituents independently selected from:\n (a) halogen, \n (b) \u2014C 3-8  cycloalkyl, optionally substituted with \u2014OH, \n (c) \u2014CN, \n (d) oxo, \n (e) \u2014O\u2014C 1-8  alkyl, optionally substituted with 1-5 halogens, \n (f) \u2014O\u2014C 3-8  cycloalkyl, \n (g) \u2014C 1-8  alkyl, optionally substituted with 1-4 substituents independently selected from halogen, \u2014OH, \u2014NH 2 , NHC(O)R c  and \u2014S(O) 2 \u2014C 1-8  alkyl, wherein R c  is selected from \u2014C 1-8  alkyl and \u2014C 3-8  cycloalkyl, \n (h) \u2014NH\u2014S(O) 2 \u2014R c , wherein R c  is selected from \u2014C 1-8  alkyl and \u2014C 3-8  cycloalkyl, \n (i) \u2014C(O)\u2014R e , R e  is selected from \u2014OH and \u2014C 1-8  alkyl, \n (j) aryl, optionally substituted with 1-3 halogens and \n (k) heterocyclyl, optionally substituted with 1-3 substituents independently selected from halogen and \u2014C 1-8  alkyl; \n \n wherein the heterocyclyl of (2) is optionally substituted with 1-3 substituents independently selected from:\n (a) halogen, \n (b) \u2014C 3-8  cycloalkyl, optionally substituted with \u2014OH, \n (c) \u2014CN, \n (d) oxo, \n (e) \u2014O\u2014C 1-8  alkyl, optionally substituted with 1-5 halogens, \n (f) \u2014O\u2014C 3-8  cycloalkyl, \n (g) \u2014C 1-8  alkyl, optionally substituted with 1-4 substituents independently selected from halogen, \u2014OH, \u2014NH 2 , NHC(O)R c  and \u2014S(O) 2 \u2014C 1-8  alkyl, wherein R c  is selected from \u2014C 1-8  alkyl and \u2014C 3-8  cycloalkyl, \n (h) \u2014NH\u2014S(O) 2 \u2014R c , wherein R c  is selected from \u2014C 1-8  alkyl and \u2014C 3-8  cycloalkyl, \n (i) \u2014C(O)\u2014R f , R f  is selected from \u2014OH, \u2014NH 2  and \u2014NH\u2014C 1-8  alkyl, \n (j) aryl, optionally substituted with 1-3 halogens, and \n (k) heterocyclyl optionally substituted with 1-3 substituents independently selected from halogen and \u2014C 1-8  alkyl; \n \n R 2  is selected from:\n (1) C 1-8  alkyl, \n (2) C 3-8  carbocyclyl, \n (3) aryl, and \n (4) heterocyclyl; \n wherein the C 1-8  alkyl of (1) is optionally substituted with 1-3 substituents independently selected from:\n (a) halogen, \n (b) \u2014C 3-8  cycloalkyl, \n (c) \u2014O\u2014C 1-8  alkyl, and \n (d) heterocyclyl; and \n \n wherein each of the C 3-8  carbocyclyl of (2), the aryl of (3), and the heterocyclyl of (4) is optionally substituted with 1-3 substituents independently selected from:\n (a) halogen, \n (b) \u2014C 3-8  cycloalkyl, \n (c) \u2014CN, \n (d) \u2014O\u2014C 1-8  alkyl, optionally substituted with 1-3 halogens and \n (e) \u2014C 1-8  alkyl, optionally substituted with 1-3 substituents independently selected from halogen, \u2014OH and \u2014NH 2 ; and \n \n R 3  is selected from H, halogen and \u2014C 1-8  alkyl, optionally substituted with \u2014OH.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 98.0
- Lexical Diversity: 2.08571
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16061597', '13780510', '11641284', '13501633', '11430441']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8192788011324401
- 35 USC 102 Novelty (BERT): 0.5593874752660665
- Combined Prediction Score: 0.7932896685458027
- Mean Citation Score: 392.197194
- Max Citation Score: 435.63135
- Similarity Product: 354.0431952178269

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test