PATENT CLAIM ANALYSIS

Application Number: 15868856
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["382", "128000"]

Abstract:
Techniques for improved diagnosis, treatment, and monitoring of corneal pathologies use enhanced mapping of the cornea or corneal regions, to develop three-dimensional mapping of corneal thickness, while retaining particular corneal micro-layer thickness data. Anterior and posterior surface identifications, along with surface apex determinations, are used for registration of segmentation of these micro-layers. 3D heat maps and bull's-eye maps are generated from resulting thickness date. The maps provided enhanced evaluation and diagnosis of a corneal pathologies, such as keratoconus, pellucid marginal degeneration, post-refractive surgery ectasia, keratoglobus, corneal transplant rejection and corneal transplant failed grafts, Fuchs dystrophy, corneal limbal stem cell deficiency, dry eye syndrome, and post-corneal collagen crosslinking evaluation.

Claim (Index 12):
The method of  claim 1 , wherein the diagnosable condition comprises limbal stem cell deficiency, basal epithelial cells thinning, or absence indicates corneal limbal stem cell deficiency, and wherein the identified one or more of the plurality biologically-defined micro-layers of the cornea comprises basal epithelial layer, the method further comprising:\n developing the thickness map as a heat map of basal epithelial layer, the heat map having a color coding that differentiates minimum thickness regions of the basal epithelial layer, normal thickness regions of the basal epithelial layer, and maximum thickness regions of the basal epithelial layer.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 86.0
- Lexical Diversity: 1.5875
- Patent Class: 382.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14247903', '14481660', '12275518', '12897131', '13441733']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.3617782328817907
- 35 USC 102 Novelty (BERT): 0.5275103744124747
- Combined Prediction Score: 0.3783514470348591
- Mean Citation Score: 288.478588
- Max Citation Score: 355.7005
- Similarity Product: 252.4749657812416

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test