PATENT CLAIM ANALYSIS

Application Number: 15880385
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "300000"]

Abstract:
Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of Formula (I): wherein R 1 , R 2 , and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Claim (Index 8):
The compound of  claim 1 , wherein the compound has structural Formula (III): wherein: R 1  is chosen from aryl and heteroaryl, and may be optionally substituted with one or more R 3  substituents; X is chosen from CR 4b  and N; each R 3  is independently chosen from hydrogen, \u2014C 1-4 alkyl, \u2014OC 1-4 alkyl, \u2014NHC 1-4 alkyl, \u2014N(C 1-4 alkyl) 2 , cyano, \u2014C(O)N(R 6 ) 2 , \u2014C(O)C 1-4 alkyl, haloalkyl, oxo, and halo; R 4b  is chosen from hydrogen, \u2014C 1-4 alkyl, \u2014OC 1-4 alkyl, aryl, heteroaryl, haloalkyl, haloalkoxy, and halo; R 4c  is chosen from hydrogen, \u2014C 1-4 alkyl, \u2014OC 1-4 alkyl, \u2014OC 1-6 cycloalkyl, and \u2014OC 1-6  heterocycloalkyl; R 6  is chosen from hydrogen and \u2014C 1-4 alkyl; R 11  is chosen from hydrogen and \u2014C 1-4 alkyl, optionally substituted with \u2014OPO(OR 12 ) 2 , \u2014OC(O)R 13 , or an amino acid; and R 12  is chosen from hydrogen and \u2014C 1-6 alkyl; R 13  is \u2014C 1-6  alkyl.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 86.0
- Lexical Diversity: 1.37778
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15005627', '15609876', '14604016', '14603937', '15737535']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8010557009983789
- 35 USC 102 Novelty (BERT): 0.5352241339636231
- Combined Prediction Score: 0.7744725442949033
- Mean Citation Score: 333.2663320000001
- Max Citation Score: 369.8901
- Similarity Product: 325.1528685477734

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test