PATENT CLAIM ANALYSIS

Application Number: 16122975
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "269000"]

Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Claim (Index 7):
A compound according to  claim 1 , or a stereoisomer, an enantiomer, a diastereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein:\n R 1 , at each occurrence, is independently selected from \u2014CH 2 OH, \u2014OCH 3 , \u2014OCH 3 , \u2014OCF 3 , OCH 2 Ph, \u2014C(\u2550O)NR a R a , \u2014NR a R a , CH 3 , CH 2 CH 3 , CH(CH 3 ) 2 , and cyclopropyl; R 2  is independently selected from C 1-4  alkyl substituted with 0-3 R e ; C2-4 alkenyl, phenyl substituted with 0-3 R e , 5- to 6-membered heteroaryl substituted with 0-3 R e , C 3-6  cycloalkyl, and CH 2 O(CH 2 ) 1-3 CH3; R 3  is independently selected from H and C 1-4  alkyl: R 4  is independently selected from \u2014(CHR 7 ) 1-4 \u2014R 6 , \u2014(CH 2 )1-30R 6 , \u2014(CH 2 ) 1-3 NHR 6 , and \u2014(CH 2 ) 0-3 NHC(\u2550O)R 6 ; R 6 , at each occurrence, is independently selected from \u2014(CR 7 R 7 ) n -aryl, \u2014(CR 7 R 7 ) n \u2014C 3-6  cycloalkyl, and \u2014(CR 7 R 7 ) n -heteroaryl, each substituted with 0-3 R 8 ; R 7 , at each occurrence, is independently selected from H, C 1-4  alkyl, and aryl; R 8 , at each occurrence, is independently selected from H, F, Cl, \u2014OR b , \u2014NR a R a , C 1-4  alkyl substituted with 0-3 R e , phenyl substituted with 0-3 R e , and heterocyclyl substituted with 0-3 R e ; R a , at each occurrence, is independently selected from H, C 1-6  alkyl substituted with 0-5 R e , \u2014(CH 2 ) n \u2014phenyl substituted with 0-5 R e , and \u2014(CH 2 ) n -heteroaryl substituted with 0-5 R e ; R b , at each occurrence, is independently selected from H, C 1-6  alkyl substituted with 0-5 R e , \u2014(CH 2 ) n \u2014C 3-10  carbocyclyl substituted with 0-5 R e , and \u2014(CH 2 ) n -heterocyclyl substituted with 0-5 R e ; R e , at each occurrence, is independently selected from F, Cl, Br, CN, NO 2 , \u2550O, CO 2 H, C 1-6  alkyl (optionally substituted with F and CO, OH, OCH 3 , OCF 3 , \u2014(CH 2 ) n \u2014C 3-6  cycloalkyl, \u2014(CH 2 ) n \u2014C 4-6  heterocyclyl, \u2014(CH 2 ) n -aryl, \u2014(CH 2 ) n -heteroaryl; and n is independently selected from zero, 1, 2, 3, and 4.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 97.0
- Lexical Diversity: 1.16667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15468230', '15767364', '16309161', '16061365', '15171276']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8149072472672286
- 35 USC 102 Novelty (BERT): 0.5527258979847317
- Combined Prediction Score: 0.788689112338979
- Mean Citation Score: 382.398828
- Max Citation Score: 411.5391
- Similarity Product: 381.12074965859057

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test