PATENT CLAIM ANALYSIS

Application Number: 15779852
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["564", "153000"]

Abstract:
The present invention relates to a preparation method of a long-chain compound, which includes the following steps: (1) carrying out condensation reaction on H—R 2  and R 5 N-Glu(OR 4 )—OR 3 , wherein, R 3  is a carboxyl protecting group, R 4  is a carboxyl activating group, and R 5  is an amino protecting group; obtaining a compound of formula II; (2) removing carboxyl protecting group R 3  and amino protecting group R 5  of the compound shown in formula II to obtain a compound of formula III; (3) carrying out condensation reaction on the compound shown in formula III and to obtain a compound shown in formula I. The method reduces the time of deprotection, and all the reactions can be carried out in a solvent with low boiling point. The post-processing requires only simple washing and recrystallization to obtain the product with higher purity, so the method is suitable for large-scale production.

Claim (Index 3):
The preparation method of the compound shown in formula I according to  claim 1 , wherein a protecting group R 5 N-Glu(OR 4 )\u2014OR 3  in step (1) is obtained by activating a carboxyl group in R 5 N-Glu(OH)\u2014OR 3  to form an active ester.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 93.0
- Lexical Diversity: 2.15854
- Patent Class: 564.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14915740', '15738876', '13699869', '15039271', '13881751']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7124089940231452
- 35 USC 102 Novelty (BERT): 0.5249840988348257
- Combined Prediction Score: 0.6936665045043132
- Mean Citation Score: 243.42368800000003
- Max Citation Score: 251.55093
- Similarity Product: 174.58783195991634

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test