PATENT CLAIM ANALYSIS

Application Number: 15996210
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-09
Patent Classification: ["514", "355000"]

Abstract:
A pharmaceutical composition can include: a marmelin analog compound, and a pharmaceutically acceptable carrier having the compound. The compound can be present in a therapeutically effective amount to treat or inhibit a disease state. The disease state can be cancer. The cancer can be selected from brain cancers, head and neck cancers, thyroid cancers, gastrointestinal cancers, esophageal cancers, stomach cancers, pancreatic cancers, liver cancers, colo-rectal cancers, lung cancers, kidney cancers, prostate cancers, bladder cancers, testicular cancers, breast cancers, ovarian cancers, cervical cancers, and melanomas. The carrier includes a cyclodextrin, which may form a complex with the compound. The compounds and compositions can be used to treat or inhibit progression of cancers. Colo-rectal, bladder, and prostate cancers are examples of some of the cancers that can be treated with the marmelin analog compounds.

Claim (Index 3):
The compound of  claim 1 , wherein R 1  or R 2  each independently includes one or more of hydrogen, C 1 -C 24  alkyl, C 2 -C 24  alkenyl, C 2 -C 24  alkynyl, C 5 -C 20  aryl, C 6 -C 24  alkaryl, C 6 -C 24  aralkyl, halo, hydroxyl, sulfhydryl, C 1 -C 24  alkoxy, C 2 -C 24  alkenyloxy, C 2 -C 24  alkynyloxy, C 1 -C 20  aryloxy, acyl, C 2 -C 24  alkylcarbonyl (\u2014CO-alkyl), C 6 -C 20  arylcarbonyl (\u2014CO-aryl), acyloxy (\u2014O-acyl), C 2 -C 24  alkoxycarbonyl (\u2014(CO)\u2014O-alkyl), C 6 -C 20  aryloxycarbonyl (\u2014(CO)\u2014O-aryl), halocarbonyl (\u2014CO)\u2014X, wherein X is halo), C 2 -C 24  alkylcarbonato (\u2014O\u2014(CO)\u2014O-alkyl), C 6 -C 20  arylcarbonato (\u2014O\u2014(CO)\u2014O-aryl), carboxy (\u2014COOH), carboxylato (\u2014COO \u2212 ), carbamoyl (\u2014(CO)\u2014NH 2 ), mono-(C 1 -C 24  alkyl)-substituted carbamoyl (\u2014(CO)\u2014NH(C 1 -C 24  alkyl)), di-(C 1 -C 24  alkyl)-substituted carbamoyl (\u2014(CO)\u2014N(C 1 -C 24  alkyl) 2 ), mono-substituted arylcarbamoyl (\u2014(CO)\u2014NH-aryl), thiocarbamoyl (\u2014(CS)\u2014NH 2 ), carbamido (\u2014NH\u2014(CO)\u2014NH 2 ), cyano (\u2014C\u2261N), isocyano (\u2014N + \u2261C \u2212 ), cyanato (\u2014O\u2014C\u2261N), isocyanato (\u2014O\u2014N + \u2261C \u2212 ), isothiocyanato (\u2014S\u2014C\u2261N), azido (\u2014N\u2550N + \u2550N \u2212 ), formyl (\u2014(CO)\u2014H), thioformyl (\u2014(CS)\u2014H), amino (\u2014NH 2 ), mono- and di-(C 1 -C 24  alkyl)-substituted amino, mono- and di-(C 5 -C 20  aryl)-substituted amino, C 2 -C 24  alkylamido (\u2014NH\u2014(CO)-alkyl), C 6 -C 20  arylamido (\u2014NH\u2014(CO)-aryl), imino (\u2014CR\u2550NH), alkylimino (\u2014CR\u2550N (alkyl), arylimino (\u2014CR\u2550N(aryl), nitro (\u2014NO 2 ), nitroso (\u2014NO), sulfo (\u2014SO 2 \u2014OH), sulfonato (\u2014S 2 \u2014O \u2212 ), C 1 -C 24  alkylsulfanyl (\u2014S-alkyl), alkylthio, arylsulfanyl (\u2014S-aryl), arylthio, C 1 -C 24  alkylsulfinyl (\u2014(SO)-alkyl), C 5 -C 20  arylsulfinyl (\u2014(SO)-aryl), C 1 -C 24  alkylsulfonyl (\u2014SO 2 -alkyl), C 5 -C 20  arylsulfonyl (\u2014SO 2 -aryl), phosphono (\u2014P(O)(OH) 2 ), phosphonato (\u2014P(O)(O \u2212 ) 2 ), phosphinato (\u2014P(O)(O\u2014)), phospho (\u2014PO 2 ), phosphino (\u2014PH 2 ), derivatives thereof, and combinations thereof whether substituted or unsubstituted or whether carbon backboned or having hetero atoms.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 94.0
- Lexical Diversity: 2.23611
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11608197', '12530429', '11823498', '13700373', '14029066']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7611949996308044
- 35 USC 102 Novelty (BERT): 0.4748995489304743
- Combined Prediction Score: 0.7325654545607714
- Mean Citation Score: 196.725428
- Max Citation Score: 202.50638
- Similarity Product: 168.34334052247763

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test