PATENT CLAIM ANALYSIS

Application Number: 15744485
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "492000"]

Abstract:
Methods for reducing platinum drug-induced toxicity in a cell expressing Organic Cation Transporter 2 (OCT2), methods for reducing platinum drug-induced toxicity in a subject, methods for treating cancer, methods for increasing efficacy of platinum drug treatment in a subject, and pharmaceutical compositions are described. The described methods and compositions include an OCT2 inhibitor where the OCT2 inhibitor is buflomedil or a salt thereof, dolutegravir or a salt thereof contains an imidazole, or is miconazole or a salt thereof.

Claim (Index 19):
The method of  claim 17 , wherein the neurotoxicity is assessed by a measurement selected from sensory nerve action potential, sensory nerve conduction velocity, cold pain threshold, heat pain threshold, mechanical pain threshold, cold detection threshold, warm detection threshold, mechanical detection threshold, vibration perception threshold, current perception threshold, pinprick sensibility, deep tendon reflexes and grip strength.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 86.0
- Lexical Diversity: 1.83333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12836398', '13147751', '14175295', '11638193', '15314200']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7863361436170623
- 35 USC 102 Novelty (BERT): 0.5120493700014781
- Combined Prediction Score: 0.7589074662555039
- Mean Citation Score: 256.733086
- Max Citation Score: 260.66200000000003
- Similarity Product: 166.94787637853625

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test