PATENT CLAIM ANALYSIS

Application Number: 15891616
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "032000"]

Abstract:
Certain embodiments of the invention are directed to evaluating and identifying cells by recording and interpreting a time-dependent signal produced by unique cell respiration and permeability attributes of isolated viable cells.

Claim (Index 1):
A method for detecting antimicrobial response of microbes in a sample comprising:\n (a) contacting a sample comprising microbes with a reporter forming a sample mixture; (b) dividing the sample mixture into at least two portions, wherein a first portion is treated with an antimicrobial substance forming a test portion and the second portion is a control portion; (c) partitioning the test portion and control portion into small volumes forming small volume partitions having one microbe or a natural aggregation of microbes per small volume partition; (d) incubating the small volume partitions over time at a specific temperature or temperatures; (e) monitoring optical characteristics of the small volume partitions during the incubation time, wherein the optical characteristics include the amount of optical signal produced by interaction of the reporter with the microbe or environment in the small volume partition; (f) constructing an optical signal waveform for each small volume partition resulting in a small volume partition waveform; and (g) comparing the optical signal waveform shapes of the small volume partitions derived from the control portion to the optical signal waveform shapes of the small volume partitions derived from the test portion to determine the sensitivity of the microbes to the antimicrobial substance.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 88.0
- Lexical Diversity: 1.18519
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15891649', '15891542', '15833629', '15466377', '13487030']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5015382828083238
- 35 USC 102 Novelty (BERT): 0.5477821051955196
- Combined Prediction Score: 0.5061626650470434
- Mean Citation Score: 342.965836
- Max Citation Score: 395.99808
- Similarity Product: 365.6632284711457

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test