PATENT CLAIM ANALYSIS

Application Number: 16000954
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "265100"]

Abstract:
Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I: These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis.

Claim (Index 15):
The pharmaceutical composition of  claim 9  wherein said side chain of Formula I has one or more double bonds comprising E-isomers and Z-isomers.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 94.0
- Lexical Diversity: 1.44828
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13558873', '15342359', '12242988', '12260502', '15769223']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7672273853046234
- 35 USC 102 Novelty (BERT): 0.5802982656142794
- Combined Prediction Score: 0.7485344733355891
- Mean Citation Score: 389.297826
- Max Citation Score: 496.8058
- Similarity Product: 383.41738431489466

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test