PATENT CLAIM ANALYSIS

Application Number: 16041875
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["514", "230500"]

Abstract:
The present invention provides 5-HT3 receptor antagonists of Formula (I): which are useful for the treatment of diseases treatable by inhibition of 5-HT3 receptor such as emesis, pain, drug addiction, neurodegenerative and psychiatric disorders, and GI disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Claim (Index 16):
Use of a compound of Formula (I): wherein: Z is O or NR a  where R a  is hydrogen or C 1-6  alkyl; R 1  is a ring of the formula (a)-(h) below: R 2  is hydrogen, C 1-6  alkyl, or C 1-6  haloalkyl; each R 3  is independently hydrogen, C 1-6  alkyl, C 1-6  alkoxy, C 1-6  haloalkoxy, or halo and can be present on any carbon atom in the rings; R 4  is pyridinyl or pyrazolyl optionally substituted with one or two substituents independently selected from C 1-6  alkyl, C 1-6  haloalkyl, C 1-6  haloalkoxy, C 1-6  alkoxy, cyano, or halo; all of X 1 , X 2 , X 3 , and X 4  are CR 5  or one of X 1 , X 2 , X 3 , and X 4  is N and the others are CR 5 ; each R 5  is independently hydrogen, C 1-6  alkyl, halo, hydroxy, or cyano provided that at least one of R 5  is hydrogen; X 5  is N or CR 6  where R 6  is hydrogen, C 1-6  alkyl, or halo; or a pharmaceutically acceptable salt thereof or N-oxide thereof; in the treatment of at least one disease, disorder, or condition treatable by inhibition of the 5-HT3 receptor in a subject.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 95.0
- Lexical Diversity: 1.36364
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14645639', '13943634', '15599239', '14415712', '15064407']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8673668039142512
- 35 USC 102 Novelty (BERT): 0.6475813302910713
- Combined Prediction Score: 0.8453882565519333
- Mean Citation Score: 573.301994
- Max Citation Score: 605.9439
- Similarity Product: 603.3425679674683

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test