PATENT CLAIM ANALYSIS

Application Number: 16058194
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2020-02
Patent Classification: ["null", "null"]

Abstract:
A method for parallel accumulation and serial fragmentation of ions, wherein ions are injected into a device capable of serial ejection using a pseudopotential barrier created by an RF voltage. In all instances, the ions may be filtered prior to accumulation in the device capable of serial ejection. In some cases this filtering may take the form of discrete isolation windows using isolation waveforms with multiple notches. In some cases these waveforms may be applied to a quadrupole mass filter. Following accumulation of the precursor ions, the initial population may be serially ejected using a pseudopotential barrier created by an RF voltage. Following serial ejection, the individual precursor ion populations are analyzed. In some cases, this analysis might involve additional rounds of ion isolation and manipulation (e.g., MSn, CID, ETD, etc.).

Claim (Index 15):
A mass spectrometer system comprising:\n (i) an ionization source; (ii) a mass filter apparatus configured to receive ions from the ionization source; (iii) a fragmentation or reaction cell configured to receive ions filtered according to mass-to-charge ratio (m/z) by the mass filter and to trap and/or fragment or react the received ions so as to thereby generate product ions; (iv) a mass analyzer configured to receive, mass analyze and detect the product ions; (v) an ion guide having an axis, the ion guide comprising:\n (a) an entrance lens configured to receive the filtered ions from the mass filter; \n (b) an exit lens disposed downstream from the entrance lens and configured to transmit the filtered ions to the fragmentation or reaction cell; and \n (c) a plurality of electrodes disposed between the entrance and exit lenses; and \n (vi) one or more power supplies electrically coupled to the ion guide, the fragmentation or reaction cell and the mass analyzer, the one or more power supplies are configured to:\n supply an oscillatory radio-frequency (RF) voltage to the plurality of electrodes that confines ions within the ion guide to a vicinity of the axis; \n supply an auxiliary radio-frequency (RF) voltage waveform either to the exit lens or, with phase synchronicity, to all of the electrodes disposed between the entrance and exit lenses; and \n supply a variable DC potential difference between the plurality of electrodes and the exit lens.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 96.0
- Lexical Diversity: 1.89873
- Patent Class: nan
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11409169', '12111484', '11133724', '11394504', '14631959']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5666484577778775
- 35 USC 102 Novelty (BERT): 0.5105571418003323
- Combined Prediction Score: 0.561039326180123
- Mean Citation Score: 300.9517
- Max Citation Score: 308.9958200000001
- Similarity Product: 235.24797444501883

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test