PATENT CLAIM ANALYSIS

Application Number: 16056694
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["424", "443000"]

Abstract:
A method for producing a patch comprising a support layer and an adhesive agent layer comprises: a mixture preparation step of mixing asenapine or a pharmaceutically acceptable salt thereof with sodium acetate whose particle diameter D 50  at a cumulative volume of 50% in a particle diameter distribution is 40 to 1000 μm, in such a manner that the sodium acetate and sodium diacetate generated from the sodium acetate have a particle diameter D 50  of 10 μm or smaller, thereby obtaining a mixture containing the sodium diacetate and the asenapine or pharmaceutically acceptable salt; and an adhesive-agent-layer formation step of forming the adhesive agent layer comprising the sodium diacetate, the asenapine or pharmaceutically acceptable salt, and a pressure-sensitive adhesive base agent, by using an adhesive agent layer composition obtained by mixing the mixture with the pressure-sensitive adhesive base agent.

Claim (Index 2):
The patch according to  claim 1 , wherein when a content of the asenapine and/or pharmaceutically acceptable salt thereof in terms of free asenapine in the adhesive agent layer is 6.4 mg, an AUC 0-inf  of free asenapine when the patch is brought into contact with skin for 24 hours is 36 ng\u00b7hr/mL or more.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 96.0
- Lexical Diversity: 2.12857
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14416964', '15454066', '15331939', '14417205', '14317976']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8023816351248607
- 35 USC 102 Novelty (BERT): 0.5555201197038986
- Combined Prediction Score: 0.7776954835827645
- Mean Citation Score: 405.664742
- Max Citation Score: 452.80746
- Similarity Product: 315.7203832234668

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test