PATENT CLAIM ANALYSIS

Application Number: 16137805
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["506", "016000"]

Abstract:
Disclosed are methods for identifying one or more amino acid molecules and nucleic acid molecules encoding such amino acid molecules of at least two proteomes that are conserved, unique or express at higher or lower levels in at least one of the proteomes. Expression libraries are used that produce the proteome, and in one embodiment, may produce the proteome from at least one cDNA expression library in one to five reactions. Anti-proteome antibodies are prepared that selectively bind to one of the proteomes and binding with at least one second proteome compared.

Claim (Index 34):
A method for producing a molecule for use as a therapeutic molecule, the method comprising,\n a) generating at least one first DNA expression library of a first recombinant proteome of a first organism by preparing fragments of the genome of said first organism of 0.3 to 1.5 kbp, size-fractionating said fragments into up to five fractions, and cloning said fragments into vectors; b) generating at least one second DNA expression library of at least one second recombinant proteome that is a different biotype of said first organism or is a different organism from said first organism by preparing fragments of the genome of said first organism of 0.3 to 1.5 kbp, size-fractionating said fragments into up to five fractions, and cloning said fragments into vectors; c) expressing said at least one first expression library and said at least one second expression library in a host to produce said first and said at least one second recombinant proteome; d) harvesting said first and said at least one second recombinant proteome expressed by said first and said at least one second libraries; e) generating enhanced anti-proteome antibodies which selectively bind to the proteins of said first recombinant proteome; f) contacting said at least one second recombinant proteome with said anti-proteome antibodies to allow binding of said proteins to said antibodies and identifying amino acid molecules by (i) detecting any of said amino acid molecules conserved between said first and said at least one second recombinant proteomes, or (ii) detecting any of said amino acid molecules unique to at least one of said recombinant proteomes to identify said amino acid molecule; and g) using at least one of said amino acid molecules or a nucleic acid that expresses a sequence comprising said amino acid molecule as a therapeutic molecule.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 97.0
- Lexical Diversity: 1.81481
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14827551', '10470048', '10372003', '10153159', '13129527']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4929746315563072
- 35 USC 102 Novelty (BERT): 0.5903725503244031
- Combined Prediction Score: 0.5027144234331168
- Mean Citation Score: 239.12622400000004
- Max Citation Score: 476.17538
- Similarity Product: 456.0968579481793

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test