PATENT CLAIM ANALYSIS

Application Number: 15747320
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "04400A"]

Abstract:
The present invention relates to the 14-3-3 protein which is a non-alcoholic fatty liver regulating factor. According to the present invention, two isoform proteins of 14-3-3, i.e., 14-3-3β and 14-3-3γ, are different regulating factors for regulating the transcriptional activity of PPARγ 2 . 14-3-3β increases the transcriptional activity of PPARγ 2  by binding to PPARγ 2 , on the other hand, 14-3-3γ plays a role in decreasing the transcriptional activity of PPARγ 2 . Thus, 14-3-3β and 14-3-3γ, which are PPARγ 2  regulating factors, are proteins that play a vital role in lipid metabolism, and may be used as a target for the prevention or treatment of fatty liver.

Claim (Index 9):
A method of preventing or treating non-alcoholic fatty liver, the method comprising administering an inhibitor against a 14-3-3\u03b2 protein to a subject,\n wherein the inhibitor is an antibody against the 14-3-3\u03b2 protein.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 86.0
- Lexical Diversity: 2.0339
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11262645', '14777104', '12708803', '15759588', '13178986']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7458360848883632
- 35 USC 102 Novelty (BERT): 0.4904919388868567
- Combined Prediction Score: 0.7203016702882126
- Mean Citation Score: 216.46709200000004
- Max Citation Score: 219.20714
- Similarity Product: 159.89869871471765

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test