PATENT CLAIM ANALYSIS

Application Number: 16029299
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-12
Patent Classification: ["424", "093710"]

Abstract:
The present disclosure provides systems for immune cell regulation and methods of immunotherapy. Systems of the present disclosure for immune cell regulation comprise a chimeric receptor polypeptide, a chimeric adaptor polypeptide, a gene modulating polypeptide (GMP), and a cleavage moiety.

Claim (Index 6):
The method of  claim 1 , wherein the immune regulatory is selected from A2AR, B7.1, B7-H3/CD276, B7-H4/B7S1/B7x/Vtcn1, B7-H6, BTLA/CD272, CCR4, CD122, 4-1BB/CD137, CD27, CD28, CD40, CD47, CD70, CISH, CTLA-4/CD152, DR3, GITR, ICOS/CD278, IDO, KIR, LAG-3, OX40/CD134, PD-1/CD279, PD2, PD-L1, PD-L2, TIM-3, and VISTA/Dies1/Gi24/PD-1H (C10orf54).

Metadata:
- Claim Count in Document: 40.0
- Percentile: 95.0
- Lexical Diversity: 1.56667
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15806756', '15403058', '15583658', '15096971', '15543220']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7627929539195233
- 35 USC 102 Novelty (BERT): 0.5664462836464568
- Combined Prediction Score: 0.7431582868922166
- Mean Citation Score: 400.062444
- Max Citation Score: 511.30402
- Similarity Product: 299.783741472584

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test