PATENT CLAIM ANALYSIS

Application Number: 16383307
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["514", "284000"]

Abstract:
The present disclosure relates to a compound of Formula I or a non-toxic pharmaceutically acceptable salt or solvate thereof, wherein each R1, R2, R3, and R4 is independently selected from methyl (—CH 3 ) and trideuteromethyl (—CD 3 ), at least one of R1, R2, R3, and R4 is selected from trideuteromethyl (—CD 3 ). The compound is a deuterated derivative of L-tetrahydropalmatine, which not only markedly improves pharmacological effects, but also significantly reduces cardiac side effects, liver toxicity, and remarkably decreases individual differences.

Claim (Index 2):
The compound according to  claim 1  or a pharmaceutically acceptable salt or solvate thereof, wherein the compound of formula I is selected from:

Metadata:
- Claim Count in Document: 1.0
- Percentile: 100.0
- Lexical Diversity: 1.62903
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13180144', '13141310', '12143664', '14286499', '15595013']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.718673516586452
- 35 USC 102 Novelty (BERT): 0.455275314678029
- Combined Prediction Score: 0.6923336963956096
- Mean Citation Score: 149.872774
- Max Citation Score: 156.19241
- Similarity Product: 139.0243043053895

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test