PATENT CLAIM ANALYSIS

Application Number: 16072647
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-12
Patent Classification: ["514", "051000"]

Abstract:
The present invention relates to a uridine phosphoramide prodrug, the preparation method therefor, and the medicinal uses thereof. The prodrug of the present invention is a chemical compound as shown in formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The prodrug of the present invention further comprises a solvate of the chemical compound shown in formula I, of an optical isomer thereof or of a pharmaceutically acceptable salt thereof. The prodrug of the present invention can treat viral infectious diseases, particularly hepatitis C viral infectious diseases.

Claim (Index 1):
An antiviral uridine phosphoramide prodrug, which is a chemical compound as shown in formula I, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, wherein: R is independently selected from substituted or unsubstituted benzyl groups, substituted or unsubstituted C 5 -C 50  linear or cyclic natural product fragments, or is selected from semi-synthetic or full-synthetic saccharides, vitamins, alcohols, and analogue fragments thereof after being structurally transformed and modified; R 1 , R 2  and R 3  are each independently selected from H, substituted or unsubstituted C 1 -C 10  linear hydrocarbyl, C 3 -C 10  branched hydrocarbyl, C 3 -C 10  cyclic hydrocarbyl, C 6 -C 10  aryl or heteroaryl, wherein the substituents are one to three heteroatoms independently selected from O, S, N and Se, or substituted or unsubstituted 3 to 8-membered rings formed by R 1  and R 2 , R 1  and R 3 , and R 2  and R 3  together with the structural parts to which they are attached; and Z is independently selected from O, S, Se, \u2014NH\u2014, or \u2014CH 2 \u2014; the prodrug further comprising: a solvate of the chemical compound as shown in formula I or a pharmaceutically acceptable salt thereof, and an optical isomer thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 95.0
- Lexical Diversity: 2.15217
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13838071', '15548776', '11660907', '15025618', '11577963']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7658233789184195
- 35 USC 102 Novelty (BERT): 0.4999156655884085
- Combined Prediction Score: 0.7392326075854184
- Mean Citation Score: 255.888808
- Max Citation Score: 265.02206
- Similarity Product: 203.7783150681805

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test