PATENT CLAIM ANALYSIS

Application Number: 15961886
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "440000"]

Abstract:
A method for knocking out a human RSPO2 gene targeted with CRISPR-Cas9 specificity includes steps of: 1) designing the sgRNA of the human RSPO2 gene targeted; and 2) constructing a CRISPR-Cas9 recombinant lentivirus vector for knocking out the RSPO2 gene. A method for preparing a lentiviral-packaged system for knocking out a human RSPO2 gene targeted with CRISPR-Cas9 specificity includes steps of: 1) designing the sgRNA of the human RSPO2 gene targeted; 2) constructing a CRISPR-Cas9 recombinant lentivirus vector for knocking out the RSPO2 gene; and 3) processing the CRISPR-Cas9 recombinant lentivirus vector for knocking out the sgRNA of the human RSPO2 gene with lentiviral packaging, so as to obtain the lentiviral-packaged system.

Claim (Index 11):
Kits or medicines of the vector recited in  claim 9  for treating liver fibrosis.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 91.0
- Lexical Diversity: 2.97619
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15179912', '14183486', '15665201', '14258458', '14259420']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5118923354858849
- 35 USC 102 Novelty (BERT): 0.5239116472815475
- Combined Prediction Score: 0.5130942666654512
- Mean Citation Score: 306.6951160000001
- Max Citation Score: 313.19348
- Similarity Product: 228.37396694536685

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test