PATENT CLAIM ANALYSIS

Application Number: 16105283
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["422", "502000"]

Abstract:
Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

Claim (Index 95):
A method for partitioning a fluid sample, the method comprising:\n providing a microfluidic device having a substrate comprising a plurality of regions in fluid communication with an inlet; introducing a first fluid into the inlet of the microfluidic device, the first fluid comprising a biological sample and a plurality of beads, each bead comprising a reactive component for binding a target protein molecule from the biological sample to the bead; partitioning the first fluid into a plurality of fluid partitions confined within a plurality of corresponding regions of the substrate by introducing a second fluid immiscible with the first fluid into the microfluidic device and flowing the second fluid towards the plurality of regions, wherein each fluid partition comprises a subvolume of the first fluid, including a single bead, and wherein each fluid partition is separated from one another by the second fluid; and maintaining each aqueous partition in corresponding regions for detection of contents in each fluid partition.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 96.0
- Lexical Diversity: 1.64062
- Patent Class: 422.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15415156', '14737865', '14070953', '12595107', '14294737']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7000979553669553
- 35 USC 102 Novelty (BERT): 0.4975081388603755
- Combined Prediction Score: 0.6798389737162973
- Mean Citation Score: 273.55406
- Max Citation Score: 289.57425
- Similarity Product: 239.9794513188601

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test