PATENT CLAIM ANALYSIS

Application Number: 15948965
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "093300"]

Abstract:
Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, synthesizing microbial ensembles based thereon, and forming and administering endomicrobial feed supplements are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

Claim (Index 1):
A method, comprising: improving rumen function in a ruminant by administering an endomicrobial feed supplement thereto, the endomicrobial feed supplement including a synthetic microbial ensemble, including:\n selecting at least three active microorganism strains, the selected at least three active microorganism strains corresponding to at least three active microorganism strains identified by an analysis of a plurality of rumen samples collected from a sample population of ruminants, the analysis including:\n detecting the presence of one or more microorganism types and determining an absolute number of each detected microorganism type for each sample; \n measuring unique first markers and quantity thereof for each sample, each unique first marker being a marker of a microorganism strain; \n determining the absolute cell count of each microorganism strain in each sample from the absolute number of each detected microorganism type and relative quantity of unique first markers; \n determining an activity level for each microorganism strain in each sample; \n generating a set of active microorganism strains and their respective absolute cell counts for each sample; \n measuring at least one metadata associated with rumen function for each sample; \n identifying network relationships between active microorganism strains and between active microorganism strains the at least one measured metadata using associated absolute cell count data of active microorganisms strain; and \n categorizing active microorganism strains based on the identified network relationships of the active microorganism strains and the at least one measured metadata from which active microorganism strains can be selected based on at least one of predicted function and chemistry; \n preparing the at least three active microorganism strains for inclusion in an endomicrobial feed supplement; forming the endomicrobial feed supplement from the prepared at least three active microorganism strains and at least one medium; and administering the endomicrobial feed supplement to a ruminant to improve rumen function of the ruminant.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 91.0
- Lexical Diversity: 1.5
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15791391', '15217575', '15400484', '15400436', '14123757']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.708774112679953
- 35 USC 102 Novelty (BERT): 0.5809457076571343
- Combined Prediction Score: 0.6959912721776712
- Mean Citation Score: 342.415782
- Max Citation Score: 513.3741
- Similarity Product: 391.3167487525105

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test