PATENT CLAIM ANALYSIS

Application Number: 16310918
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["546", "193000"]

Abstract:
The invention provides compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof (I) wherein ring A represents group A-I or A-II (A-I, A-II) A1, A2, A3, A4 represent independently C(R4aa) or N, wherein no more than one of A1, A2, A3, and A4 represents N; A5 represents C(R4b) or N; B1, B2, B3 and B4 represent independently C(R3) or N, wherein no more than two of B1, B2, B3 and B4 represent N; n is 1 or 2; and R1, R2, R3, R4a and R4aa and R4b are as defined in the claims, as well as methods of using the compounds to treat proliferation diseases, in particular cancer.

Claim (Index 21):
The compound according to  claim 20 , or a pharmaceutically acceptable salt, solvate or hydrate thereof, wherein R2 represents fluoro, chloro, bromo, cyano, hydroxyl, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkyl wherein one or two non-adjacent carbon atoms in the alkyl other than the connecting carbon atom are replaced independently by \u2014O\u2014, \u2014OH, \u2014NH\u2014, \u2014NH 2 , \u2014N(CH 3 )\u2014, \u2014NH(CH 3 ), \u2014N(CH 3 ) 2 , or \u2014CN, or C1-C6haloalkyl wherein one or two non-adjacent carbon atoms in the haloalkyl other than the connecting carbon atom are replaced independently by \u2014O\u2014, \u2014OH, \u2014NH\u2014, \u2014NH 2 , \u2014N(CH 3 )\u2014, \u2014NH(CH 3 ), \u2014N(CH 3 ) 2  or \u2014CN, or C1-C6alkoxy, C1-C6alkoxy wherein one carbon atom in the alkoxy other than the carbon atom connected to the oxygen is replaced by \u2014O\u2014, \u2014OH, \u2014NH\u2014, \u2014NH 2 , \u2014N(CH 3 )\u2014, \u2014CN, or \u2014N(R9a)(R9b) or \u2014C1-C6alkylene-N(R9a)(R9b) and wherein R9a represents hydrogen, C1-C6alkyl wherein one or two non-adjacent carbon atoms in the alkyl are replaced independently by \u2014O\u2014, \u2014OH, \u2014NH\u2014, \u2014NH 2 , \u2014N(CH 3 )\u2014, \u2014NH(CH 3 ), \u2014N(CH 3 ) 2  or \u2014CN, or R9a represents \u2014C1-C6-alkylene-Cycle-P or Cycle-P, wherein Cycle-P represents a saturated 4- to 6-membered heterocyclic ring containing one or two heteroatoms selected from O and N(R15), wherein the heterocyclic ring is optionally substituted by one to three substituents selected from methyl, R9b represents hydrogen, methyl or ethyl, and R15 represents independently at each occurrence hydrogen or methyl.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 98.0
- Lexical Diversity: 2.11429
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15580008', '15545149', '13145323', '14552853', '14216486']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8151262768609252
- 35 USC 102 Novelty (BERT): 0.5403320079209162
- Combined Prediction Score: 0.7876468499669244
- Mean Citation Score: 361.492284
- Max Citation Score: 388.39368
- Similarity Product: 308.7726811311436

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test