PATENT CLAIM ANALYSIS

Application Number: 15899171
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "299000"]

Abstract:
Provided are compositions for inhibiting a biological activity of an aldo-keto reductase family 1, member C3 (AKR1C3) polypeptide. In some embodiments, the compositions are indomethacin derivatives that are AKR1C3-specific inhibitors. Also provided are methods for producing disclosed indomethacin derivatives that substantially lack cyclooxygenase inhibitory activity but that have AKR1C3 inhibitory activity, methods for inhibiting AKR1C3 polypeptide biological activities, and methods for treating prostate tumors in subjects.

Claim (Index 26):
A method for inhibiting undesirable aldo-keto reductase family 1, member C3 (AKR1C3) biological activity in a subject, the method comprising administering to the subject an effective amount of a compound of  claim 1 .

Metadata:
- Claim Count in Document: 49.0
- Percentile: 88.0
- Lexical Diversity: 1.53061
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15132937', '14352421', '14050937', '14993742', '12814143']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7501993937041521
- 35 USC 102 Novelty (BERT): 0.5962559521473471
- Combined Prediction Score: 0.7348050495484717
- Mean Citation Score: 393.9255059999999
- Max Citation Score: 546.6968400000002
- Similarity Product: 423.6739406442834

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test