PATENT CLAIM ANALYSIS

Application Number: 16030793
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "345000"]

Abstract:
Among the various aspects of the present disclosure is the provision of methods of treating a microglial dysfunction-associated diseases, disorder, and conditions. The present disclosure provides for a method for treating microglial dysfunction in a subject having a microglial dysfunction-associated neurodegenerative disease comprising administering to a subject a therapeutically effective amount of a microglial rescuing agent. The present disclosure also provides for a method of reversing neuronal damage in a subject having a microglial dysfunction-associated neurodegenerative disease, wherein the microglial dysfunction-associated neurodegenerative disease is characterized by a single nucleotide polymorphisms (SNPs) or mutation in Trem2 or ApoE affecting microglial functions.

Claim (Index 12):
The method of  claim 11 , wherein the therapeutically effective amount of a microglial rescuing agent results in improved microglia clustering around A\u03b2 plaques or reduced plaque-associated neurite dystrophy.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 95.0
- Lexical Diversity: 1.89474
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14780242', '15313642', '15518438', '14289996', '15647157']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7674670267119464
- 35 USC 102 Novelty (BERT): 0.5103426442524148
- Combined Prediction Score: 0.7417545884659933
- Mean Citation Score: 241.88359600000004
- Max Citation Score: 268.45264
- Similarity Product: 185.33778371076585

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test