PATENT CLAIM ANALYSIS

Application Number: 16024283
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "649000"]

Abstract:
Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

Claim (Index 12):
The process of  claim 1 , wherein the levomethadone hydrochloride comprises not more than 0.05%(500 ppm), 0.025%(250 ppm), or 0.01%(100 ppm) of an impurity selected from the group consisting of dextromethadone hydrochloride, dextromethadone, isodextromethadone, isodextromethadone hydrochloride, isolevomethadone, isolevomethadone hydrochloride, levomethadone nitrile, dextromethadone nitrile, isolevomethadone nitrile, isodextromethadone nitrile, diphenylacetonitrile, 2(S)-2-[[(4-methylphenyl)sulphonyl]amino]pentanedioic acid (N-tosyl-L-glutamic acid), a tartaric acid, and a bromocamphor sulfonic acid.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 94.0
- Lexical Diversity: 1.39474
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15245935', '14190702', '13759382', '12530214', '14465470']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7672123630429646
- 35 USC 102 Novelty (BERT): 0.6978772409398268
- Combined Prediction Score: 0.7602788508326509
- Mean Citation Score: 303.701184
- Max Citation Score: 774.36896
- Similarity Product: 702.5231509969141

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test