PATENT CLAIM ANALYSIS

Application Number: 16014446
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["424", "145100"]

Abstract:
The invention relates to a multiple-variable dose method for treating a disorder in which TNFα activity is detrimental, comprising administering to a subject in need thereof a first induction dose of an anti-TNFα antibody which ranges from 161 to 320 mg such that a threshold level of TNFα inhibitor is achieved within an induction phase; and subsequently administering to the subject at least one treatment dose of the TNFα inhibitor within a treatment phase, such that treatment occurs

Claim (Index 2):
The method of  claim 1 , wherein the disorder in which TNF\u03b1 activity is detrimental is selected from the group consisting of an autoimmune disease, an infectious disease, transplant rejection or graft-versus-host disease, malignancy, a pulmonary disorder, an intestinal disorder, a cardiac disorder, sepsis, a spondyloarthropathy, a metabolic disorder, anemia, pain, a hepatic disorder, a skin disorder, a nail disorder, vasculitis, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis, allergy, multiple sclerosis, autoimmune diabetes, autoimmune uveitis, nephrotic syndrome, inflammatory bone disorders, bone resorption disease, alcoholic hepatitis, viral hepatitis, fulminant hepatitis, coagulation disturbances, burns, reperfusion injury, keloid formation, scar tissue formation, pyrexia, periodontal disease, obesity, radiation toxicity, Behcet's disease, ankylosing spondylitis, asthma, chronic obstructive pulmonary disorder (COPD), idiopathic pulmonary fibrosis (IPF), restenosis, diabetes, a Crohn's disease-related disorder, juvenile rheumatoid arthritis (JRA), a hepatitis C virus infection, psoriatic arthritis, chronic plaque psoriasis, Crohn's disease, ulcerative colitis, psoriasis, psoriasis in combination with psoriatic arthritis (PsA) and rheumatoid arthritis.

Metadata:
- Claim Count in Document: 62.0
- Percentile: 94.0
- Lexical Diversity: 1.58824
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16014469', '15564677', '13433205', '14628068', '14229664']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7182094497184914
- 35 USC 102 Novelty (BERT): 0.5543914345573376
- Combined Prediction Score: 0.7018276482023761
- Mean Citation Score: 369.772512
- Max Citation Score: 442.74567
- Similarity Product: 271.46269927165747

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test