PATENT CLAIM ANALYSIS

Application Number: 16079868
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "04400A"]

Abstract:
Aberrantly expressed piRNAs, genetically associated piRNAs and their relationship with cancer risk and severity are provided. Compositions and methods of using piRNA for treating cancer are provided. Methods of diagnosing subjects and determining the efficacy of active agents for treating cancer are also provided. Methods of correlating variant piRNA to cancer are also disclosed.

Claim (Index 12):
The method of  claim 11 , wherein\n (i) wildtype piR-021163 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has least one rs61101785 SNP, (ii) wildtype piR-003123 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has least one rs62439721 SNP, (iii) wildtype piR-008061 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has at least one rs11074184 SNP, (iv) wildtype piR-013783 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has at least one rs8010969 SNP, (v) wildtype piR-14246 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has at least one rs8010969 SNP, (vi) wildtype piR-008286 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has at least one rs008286 SNP, (vii) wildtype piR-018495 or a close variant thereof with the same or similar activity to wildtype, or a stimulator of expression thereof is administered and the subject has at least one rs8020378 SNP, or (viii) a combination thereof.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 96.0
- Lexical Diversity: 1.63889
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13470233', '15313555', '14112296', '14020811', '15422725']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7593484300403617
- 35 USC 102 Novelty (BERT): 0.5097586640529993
- Combined Prediction Score: 0.7343894534416254
- Mean Citation Score: 233.341736
- Max Citation Score: 247.30536
- Similarity Product: 158.75100116671086

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test