PATENT CLAIM ANALYSIS

Application Number: 15874659
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "190100"]

Abstract:
The present invention provides immunogens which can be used for vaccines against non-typeable  Haemophilus influenzae  (NTHi). The protein targeted is NTHi PDE1 and is highly conserved making it a vital component necessary for bacterial pathogenesis. The protein preferably includes the C terminal fragment after cleavage between Asn269 and Gly270, when compared to the wild-type PDE1 amino acid sequence. Nucleic acid sequences, amino acid sequences, immunogenic compositions, treatments and methods of diagnosis are disclosed.

Claim (Index 18):
A method for detecting or isolating an antibody that specifically binds to  H. influenza  PDE1 or fragment thereof from a subject, comprising:\n providing an effective amount of the immunogen of any one of  claim 1 ; contacting a biological sample from the subject with the immunogen under conditions sufficient to form an immune complex between the immunogen and the antibody that specifically binds to  H. influenza  PDE1 or fragment thereof; and detecting the immune complex, thereby detecting or isolating the antibody from the subject.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.31746
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['09936362', '12336995', '11960883', '13005166', '14316935']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7353046898500386
- 35 USC 102 Novelty (BERT): 0.5101088077482803
- Combined Prediction Score: 0.7127851016398629
- Mean Citation Score: 272.78225000000003
- Max Citation Score: 279.99078
- Similarity Product: 189.2772215844333

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test