PATENT CLAIM ANALYSIS

Application Number: 16060142
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-09
Patent Classification: ["546", "082000"]

Abstract:
The present invention relates to a process for phospholipidation of imidazoquinolines and oxoadenines. More particularly, the present invention relates to a high-yielding and scalable procedure for the phospholipidation of imidazoquinolines and oxoadenines which obviates the need to isolate unstable phosphoramidite intermediates. This process may be used for the phospholipidation of toll-like receptor 7 (TLR7)-active and toll-like receptor (TLR8)-active imidazoquinolines and oxoadenines.

Claim (Index 16):
The process of  claim 12  wherein the coupling agent used with a compound of formula (III) and a compound of formula (V) is at 2.1 equivalents, the compound of formula (III) is at 2.0 equivalents, the compound of formula (V) is at 2.1 equivalents, the compound of formula (VII) is at 1.0 equivalent and the oxidizing agent for the compound of formula (IX) is at 1.5 equivalent.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 94.0
- Lexical Diversity: 1.775
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15781905', '14008805', '12578020', '13389307', '15126245']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7770818648601222
- 35 USC 102 Novelty (BERT): 0.5155919993884399
- Combined Prediction Score: 0.750932878312954
- Mean Citation Score: 259.280824
- Max Citation Score: 305.36798
- Similarity Product: 215.1253592062021

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test