PATENT CLAIM ANALYSIS

Application Number: 15864994
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "245000"]

Abstract:
Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).

Claim (Index 29):
A method of treating angioimmunoblastic T-cell lymphoma (AITL) characterized by the presence of a mutant allele of isocitrate dehydrogenase 2 (IDH2) comprising administering to a subject a therapeutically effective dose of the crystalline form of 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol methanesulfonate, wherein the crystalline form is selected from\n a) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 7.5, 9.3, 14.5, 18.8, 21.3, and 24.8\u00b0\u00b10.2\u00b0, b) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.5, 19.0, 19.4, 19.9, and 24.7\u00b0\u00b10.2\u00b0, c) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 7.1, 14.5, 17.1, and 21.8\u00b0\u00b10.2\u00b0, d) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.3, 7.2, 8.1, 12.7, and 14.9\u00b0\u00b10.2\u00b0, e) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 14.1, 19.1, 21.8, 23.5, and 25.7\u00b0\u00b10.2\u00b0, f) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 9.0, 9.2, 21.9, 22.1, 24.2, and 24.6\u00b0\u00b10.2\u00b0, g) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.5, 19.6, 20.1, and 21.6\u00b0\u00b10.2\u00b0, h) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.7, 9.1, 10.8, 19.9, and 21.9\u00b0\u00b10.2\u00b0, i) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.3, 20.0, 20.2, 20.5, 21.2, and 26.5\u00b0\u00b10.2\u00b0, j) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 7.2, 7.4, 8.0, 8.2, 16.5, and 18.6\u00b0\u00b10.2\u00b0, k) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.3, 12.7, 20.3, 20.8, and 26.5\u00b0\u00b10.2\u00b0, l) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.6, 17.5, 20.8 and 23.3\u00b0\u00b10.2\u00b0, and m) the crystalline form characterized by an X-ray powder diffraction pattern having peaks at 2\u03b8angles of 6.4, 12.9, 20.2, and 26.1\u00b0\u00b10.2\u00b0, wherein the therapeutically effective dose is from about 30 mg to about 300 mg.

Metadata:
- Claim Count in Document: 70.0
- Percentile: 86.0
- Lexical Diversity: 1.17857
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14909451', '15649551', '15612984', '14868283', '15548737']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8342979411682918
- 35 USC 102 Novelty (BERT): 0.5920742371090114
- Combined Prediction Score: 0.8100755707623638
- Mean Citation Score: 489.79634
- Max Citation Score: 507.67773
- Similarity Product: 465.4664301317812

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test