PATENT CLAIM ANALYSIS

Application Number: 15771487
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "217060"]

Abstract:
To provide a compound having an inhibitory activity for an androgen receptor. A fused pyrimidine compound represented by the following formula (I) or a pharmaceutically acceptable thereof (in the formula, X, Y, Z, R 1 , and R 2  are as defined in the specification).

Claim (Index 9):
The compound or pharmaceutically acceptable salt thereof according to  claim 1 , wherein\n X represents a cyano group or a nitro group; Y represents a halogen atom, a halogeno-C 1-3  alkyl group, a C 1-3  alkoxy group, or a C 1-3  alkyl group; Z represents a hydrogen atom or a halogen atom; R 1  is a substituent selected from the group consisting of the following groups: R 2  represents a hydrogen atom, a C 1-3  alkyl group, or a cyano group; wherein: Ra represents a phenyl group, a hydroxy-C 1-6  alkyl group, a hydroxy-heterocycloalkyl group, a C 1-6  alkoxy group which may be substituted with Rc, an amino-C 1-6  alkyl group which may be substituted with Rf, a halogeno-C 1-3  alkoxy group, a bicyclic heterocycloalkyl group, or \u2014(CH 2 ) n \u2014C(\u2550O)\u2014NRdRe; Rb represents a hydrogen atom, a halogen atom, a C 1-3  alkyl group which may be substituted with a halogen atom, or a C 1-4  alkoxy group which may be substituted with a halogen atom; or Ra and Rb are bonded to each other to form a fused ring together with the ring on which they are substituted; Rc represents a piperazinyl group which may be substituted with Rf; Rd and Re each independently represent a hydrogen atom, a C 1-3  alkyl group, a C 2-6  alkynyl group, a C 1-6  alkoxy group, a C 3-7  cycloalkyl group, a halogeno-C 1-3  alkyl group, or a C 1-6  alkyl group substituted with Rg; or NRdRe forms a 3- to 7-membered nitrogen-containing heterocyclic ring; Rf represents a C 1-6  alkyl group, a C 1-6  alkylcarbonyl group, a C 1-6  alkylsulfonyl group, a C 1-6  alkoxycarbonyl group, or a C 1-6  alkylaminocarbonyl group; Rg represents a C 1-6  alkoxycarbonylamino group; and n represents an integer of 0 or 1.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 91.0
- Lexical Diversity: 1.375
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15203059', '15893804', '15023894', '13394525', '13796928']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8544705192213283
- 35 USC 102 Novelty (BERT): 0.5890586868687844
- Combined Prediction Score: 0.8279293359860739
- Mean Citation Score: 457.957174
- Max Citation Score: 524.8892
- Similarity Product: 442.80399336943617

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test