PATENT CLAIM ANALYSIS

Application Number: 16179672
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "210210"]

Abstract:
The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Claim (Index 8):
A compound, or a pharmaceutically acceptable salt, hydrate or solvate thereof, of Formula (II): wherein:\n R 100  is selected from H, \u2014C 1 -C 6 -alkyl, \u2014C 3 -C 6 -cycloalkyl, \u2014C 1 -C 4 -alkyl-C 3 -C 6 -cycloalkyl where the alkyl or cycloalkyl groups may be substituted with one or more groups selected from halogen, \u2014OH, \u2014OMe, \u2014OCF 3 , \u2014CN; \n R 200  is selected from \u2014C 1 -C 6 -alkyl, \u2014C 3 -C 6 -cycloalkyl, \u2014C 1 -C 4 -alkyl-C 3 -C 6 -cycloalkyl where the alkyl or cycloalkyl groups may be substituted with one or more groups selected from halogen, \u2014OH, \u2014OMe, \u2014OCF 3 , \u2014CN; \n R 300  is selected from \u2014C 1 -C 6 -alkyl, \u2014C 3 -C 6 -cycloalkyl, \u2014C 3 -C 6 -heterocyclyl, \u2014C 1 -C 4 -alkyl-C 3 -C 6  cycloalkyl, \u2014SO 2 \u2014C 1 -C 6 -alkyl where the alkyl or cycloalkyl groups may be substituted with one or more groups selected from halogen, \u2014OH, \u2014OMe, \u2014OCF 3 , \u2014CN; when R 300  is a heterocycle containing a nitrogen, such as piperidine, the nitrogen atom may be substituted with \u2014C\u2550O-phenyl or \u2014C\u2550O-heteroaryl where the phenyl or heteroaryl groups may be substituted with one or more groups selected from \u2014C 1 -C 6 -alkyl, halogen, \u2014OH, \u2014OMe, \u2014OCF 3 , \u2014CF 3 , \u2014CN.

Metadata:
- Claim Count in Document: 43.0
- Percentile: 98.0
- Lexical Diversity: 1.34091
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15672627', '15320120', '15377214', '14924427', '15585626']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7768687632415228
- 35 USC 102 Novelty (BERT): 0.4891667868733872
- Combined Prediction Score: 0.7480985656047092
- Mean Citation Score: 229.845596
- Max Citation Score: 234.2343
- Similarity Product: 191.68805873479843

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test