PATENT CLAIM ANALYSIS

Application Number: 15951536
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["702", "104000"]

Abstract:
A method for determining the amount of a specific analyte by photometric assays, wherein the specific analyte in a sample reacts with an analyte specific reaction partner in a reaction mixture. At least two calibration curves are generated, the first calibration curve recorded at a first wavelength is optimized for low concentrations of the specific analyte thereby maximizing the lower detection limit and, the second calibration curve recorded at a second wavelength is optimized for high concentrations of the specific analyte thereby maximizing the upper detection limit. The optimized lower detection limit and the optimized upper detection limit results in an extended dynamic range.

Claim (Index 1):
A method for determining the amount of a specific analyte by photometric assays, wherein the specific analyte in a sample reacts with an analyte specific reaction partner in a reaction mixture, comprising the steps of:\n a) generating at least two calibration curves, wherein\n the first calibration curve recorded at a first wavelength is optimized for low concentrations of the specific analyte thereby maximizing the lower detection limit, and \n the second calibration curve recorded at a second wavelength is optimized for high concentrations of the specific analyte thereby maximizing the upper detection limit; \n b) measuring simultaneously the optical signal for the specific analyte of a sample to be determined in the reaction mixture at least at the first and second wavelengths; c) selecting either the first or the second calibration curve for quantification of the specific analyte, by the following criteria:\n for increasing calibration curves:\n if the optical signal of the first and/or the second wavelength is lower than a corresponding predetermined threshold value, the concentration of the analyte is determined by the use of the first calibration curve recorded at the first wavelength; \n if the optical signal of the first and/or the second wavelength exceeds a corresponding predetermined threshold value, the concentration of the analyte is determined by the use of the second calibration curve recorded at the second wavelength; \n \n for decreasing calibration curves:\n if the optical signal of the first and/or the second wavelength is lower than a corresponding predetermined threshold value, the concentration of the analyte is determined by the use of the second calibration curve recorded at the second wavelength; \n if the optical signal of the first and/or the second wavelength exceeds a corresponding predetermined threshold value, the concentration of the analyte is determined by the use of the first calibration curve recorded at the first wavelength, and \n \n d) quantifying the amount of the specific analyte by comparison with the selected calibration curve.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 91.0
- Lexical Diversity: 2.03704
- Patent Class: 702.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14524700', '14965560', '13504748', '13758562', '11070282']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.1964629475806438
- 35 USC 102 Novelty (BERT): 0.5364257877841005
- Combined Prediction Score: 0.2304592316009895
- Mean Citation Score: 238.474188
- Max Citation Score: 375.72107
- Similarity Product: 255.30272971028683

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test