PATENT CLAIM ANALYSIS

Application Number: 16044752
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["544", "106000"]

Abstract:
The present invention relates to compounds that act as pan-Rac inhibitors, compositions including the compounds, and methods of using the compounds. In particular, the compounds are useful for treating certain cancers such as breast cancer.

Claim (Index 1):
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein Z is selected from halogen and C 1-4  alkyl wherein said C 1-4  alkyl is optionally substituted with one or more halogen atoms; R 1 , R 2 , and R 3  are independently selected from H and halogen; X is \u2014S\u2014; A is C 1-7  alkylene wherein one or more of the methylene groups is optionally replaced with O, N(R b ), S, C(O), or phenylene; B is selected from the group: Linker is selected from a bond, \u2014C(O)\u2014, \u2014CH 2 \u2014N(R c )\u2014, \u2014CH 2 \u2014N(R d )\u2014C(O)\u2014, and C 1-2  alkylene wherein said C 1-2  alkylene is optionally substituted with OH; D is selected from: (i) a 4-7 membered ring optionally containing 1 or 2 heteroatoms independently selected from N and O; wherein said ring optionally contains a C\u2550O; and wherein said ring is optionally substituted with one or more groups selected from halogen, OH, C 1-4  alkoxy, C 1-4  alkyl optionally substituted with one or more halogen atoms, C(O)\u2014R e , phenyl optionally substituted with C 1-4  alkoxy, and a 5 or 6 membered ring containing 1 or 2 heteroatoms independently selected from N and O; (ii) \u2014N(R f )(R g ); and (iii) \u2014C(O)\u2014O\u2014C 1-4  alkyl; R b  is selected from H and C 1-4  alkyl; R c  and R d  are independently selected from H and C 1-4  alkyl, R e  is selected from C 1-4  alkyl and a 5- or 6-membered ring optionally containing 1 or 2 heteroatoms independently selected from N and O; R f  is selected from H, C 1-4  alkyl, C(O)\u2014C 1-4  alkyl, and C(O)\u2014O\u2014C 1-4  alkyl; and R g  is selected from C 1-4  alkyl, C 1-4  alkylene-O\u2014C 1-4  alkyl.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 95.0
- Lexical Diversity: 1.29032
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10894940', '15266411', '12394072', '15499443', '13822809']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8291755323952417
- 35 USC 102 Novelty (BERT): 0.5313105973132248
- Combined Prediction Score: 0.79938903888704
- Mean Citation Score: 354.313954
- Max Citation Score: 371.0986
- Similarity Product: 305.8142229062081

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test