PATENT CLAIM ANALYSIS

Application Number: 16189755
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["514", "211090"]

Abstract:
This invention relates to new benzazepine dicarboxamide compounds of the formula wherein R 1  to R 4  are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are TLR agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases.

Claim (Index 19):
A process for the manufacture of a compound of formula I as defined in  claim 1 , which process comprises:\n a) coupling a compound of the formula II wherein R 1  and R 2  are as defined in  claim 1  and PG is a protecting group, with a compound of the formula III wherein R 3  and R 4  are as defined in  claim 1 , under basic conditions in the presence of a coupling agent and removing the protecting group PG under acidic conditions to obtain a compound of the formula I wherein R 1  to R 4  are as defined in  claim 1 , and, if desired, converting the compound obtained into a pharmaceutically acceptable salt.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 98.0
- Lexical Diversity: 1.50943
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15061105', '15279114', '15432859', '16189646', '15915563']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7988369848947379
- 35 USC 102 Novelty (BERT): 0.6082586355150805
- Combined Prediction Score: 0.7797791499567722
- Mean Citation Score: 436.926212
- Max Citation Score: 529.3981
- Similarity Product: 481.3419806062221

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test