PATENT CLAIM ANALYSIS

Application Number: 15756043
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "133100"]

Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-7 protein, e.g., human Siglec-7 or a mammalian Siglec-7, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.

Claim (Index 35):
The anti-Siglec-7 antibody of  claim 32 , wherein the light chain variable domain comprises:\n (a) an HVR-L1 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 7-19 and 476, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 7-19 and 476; (b) an HVR-L2 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 20-32 and 477, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 20-32 and 477; and (c) an HVR-L3 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 33-45 and 478, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 33-45 and 478; and wherein the heavy chain variable domain comprises:\n (a) an HVR-H1 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 46-58 and 479, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 46-58 and 479; \n (b) an HVR-H2 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 59-71 and 480-482, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 59-71 and 480-482; and \n (c) an HVR-H3 comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 72-84 and 483, or an amino acid sequence with at least about 90% homology to an amino acid sequence selected from the group consisting of SEQ ID NOs: 72-84 and 483.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 88.0
- Lexical Diversity: 1.46667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14565370', '14021777', '15222849', '15182327', '15222848']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7463914715203802
- 35 USC 102 Novelty (BERT): 0.5860463742053319
- Combined Prediction Score: 0.7303569617888754
- Mean Citation Score: 461.736258
- Max Citation Score: 500.8059
- Similarity Product: 375.79818367229103

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test