PATENT CLAIM ANALYSIS

Application Number: 16183050
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-02
Patent Classification: ["424", "197110"]

Abstract:
The invention provides a conjugate of a  Neisseria meningitidis  serogroup X capsular polysaccharide and a carrier molecule. The conjugate is typically made by (a) oxidising a primary hydroxyl group in the capsular polysaccharide, to give an oxidised polysaccharide with an aldehyde group; and (b) coupling the oxidised polysaccharide to a carrier molecule via the aldehyde group, thereby giving the conjugate. The conjugate may be part of an immunogenic composition. This composition may comprise one or more further antigens, particularly capsular polysaccharides from serogroups A, W135, C and Y and conjugated forms thereof. The composition may be in an aqueous formulation. The composition is useful as a vaccine, e.g. for raising an immune response in a mammal. The invention also provides processes for making the conjugate.

Claim (Index 40):
A method of assaying a sample suspected of comprising  Neisseria meningitidis  serogroup X capsular polysaccharide comprising the steps of\n a. hydrolyzing any serogroup X capsular polysaccharide in the sample, resulting in a hydrolysate; b. subjecting the hydrolysate to liquid chromatography; and c. detecting any glucosamine-4-phosphate separated in step b.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 98.0
- Lexical Diversity: 1.84615
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14401024', '12321417', '12353409', '12321418', '12321434']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7360872748218666
- 35 USC 102 Novelty (BERT): 0.6447849156521501
- Combined Prediction Score: 0.726957038904895
- Mean Citation Score: 494.26098200000007
- Max Citation Score: 768.3376
- Similarity Product: 544.7055553155899

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test