PATENT CLAIM ANALYSIS

Application Number: 15780732
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "049000"]

Abstract:
Provided relates to conjugates including cytarabine and an amino acid for use in the treatment of cancer. Further, the subject matter relates to conjugates of cytarabine and aspartic acid for use in the treatment of hematological cancers in medically compromised patients.

Claim (Index 53):
A method of treating a neoplastic disease or a viral disease, the method comprising administering to a subject in need of such treatment a pharmaceutical composition comprising a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof, represented by the structure of formula (I):\n A-Cytarabine \u2003\u2003(I) wherein A denotes an amino acid residue, the amino acid is selected from the group consisting of aspartic acid, glutamic acid, asparagine, and glutamine; and wherein adverse effects of the compound are reduced compared to the adverse effects of the non-conjugated cytarabine so that the compound can be administered in a dosage of at least two times greater than the maximal standard of care dose of cytarabine, without the subject experiencing dose limiting toxicity, the pharmaceutical composition further comprising a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 94.0
- Lexical Diversity: 1.57143
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13762238', '12730097', '15277857', '15407122', '12267321']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6553646027107995
- 35 USC 102 Novelty (BERT): 0.5082448466314645
- Combined Prediction Score: 0.6406526271028661
- Mean Citation Score: 262.23539600000004
- Max Citation Score: 271.10385
- Similarity Product: 194.08791724010112

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test