PATENT CLAIM ANALYSIS

Application Number: 16283531
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["435", "006120"]

Abstract:
The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

Claim (Index 32):
A method for nucleic acid sequencing or identification, comprising:\n (a) providing an array comprising (i) a plurality of sensors, and (ii) a plurality of nucleic acid molecules immobilized adjacent to said plurality of sensors; (b) contacting said plurality of nucleic acid molecules with a plurality of nucleotide analogues in presence of polymerizing enzymes to incorporate at least one nucleotide analogue of said plurality of nucleotide analogues into at least one growing strand complementary to a nucleic acid molecule of said plurality of nucleic acid molecules; (c) using a sensor of said plurality of sensors to perform at least one measurement of charge or conductivity, or a change in charge or conductivity, associated with incorporation of said at least one nucleotide analogue into said at least one growing strand; and (d) using said at least one measurement of (c) to identify said at least one nucleotide analogue incorporated into said at least one growing strand complementary to said nucleic acid molecule.

Metadata:
- Claim Count in Document: 170.0
- Percentile: 99.0
- Lexical Diversity: 1.42
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16007829', '16007969', '14119859', '16283544', '13838816']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6673943673298888
- 35 USC 102 Novelty (BERT): 0.5460775083472229
- Combined Prediction Score: 0.6552626814316221
- Mean Citation Score: 395.268146
- Max Citation Score: 409.00458
- Similarity Product: 348.9889221497583

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test