PATENT CLAIM ANALYSIS

Application Number: 15743424
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["546", "276700"]

Abstract:
The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D 1 , D 2 , D 3 , X, Y, A 1 , A 2 , R 1 , R 5  and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis:

Claim (Index 18):
A pharmaceutical composition comprising the compound of  claim 1  or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier, and an additional active ingredient selected from:\n (i) an HMG-CoA reductase inhibitor; \n (ii) a bile acid sequestrant; \n (iii) niacin and a related compound; \n (iv) a PPAR\u03b1 agonist; \n (v) a cholesterol absorption inhibitor; \n (vi) an acyl CoA:cholesterol acyltransferase (ACAT) inhibitor; \n (vii) a phenolic anti-oxidant; \n (viii) a microsomal triglyceride transfer protein (MTP)/ApoB secretion inhibitor; \n (ix) an anti-oxidant vitamin; \n (x) a thyromimetic; \n (xi) a LDL (low density lipoprotein) receptor inducer; \n (xii) a platelet aggregation inhibitor; \n (xiii) vitamin B12 (also known as cyanocobalamin); \n (xiv) folic acid or a pharmaceutically acceptable salt or ester thereof; \n (xv) an FXR or LXR ligand; \n (xvi) an agent that enhances ABCA1 gene expression; \n (xvii) an ileal bile acid transporter; or \n (xviii) a niacin receptor agonist.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 86.0
- Lexical Diversity: 1.63043
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14908180', '13660010', '15329284', '15104351', '15028306']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8257928684521377
- 35 USC 102 Novelty (BERT): 0.5651389784544157
- Combined Prediction Score: 0.7997274794523656
- Mean Citation Score: 434.067694
- Max Citation Score: 454.36414
- Similarity Product: 423.0148804128158

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test