PATENT CLAIM ANALYSIS

Application Number: 16026397
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["546", "323000"]

Abstract:
The present invention relates to compounds comprising a protecting group moiety-tag moiety conjugate, a method of purification and monoconjugates obtained from such method of purification.

Claim (Index 15):
The compound of  claim 13 ; wherein L 2  of formula (IIa) is selected from the group consisting of -T-, \u2014C(O)O\u2014, \u2014O\u2014, \u2014C(O)\u2014, \u2014C(O)N(R y1 )\u2014, \u2014S(O) 2 N(R y1 )\u2014, \u2014S(O)N(R y1 )\u2014, \u2014S(O) 2 \u2014, \u2014S(O)\u2014, \u2014N(R y1 )S(O) 2 N(R y1a )\u2014, \u2014S\u2014, \u2014N(R y1 )\u2014, \u2014OC(OR y1 )(R y1a )\u2014, \u2014N(R y1 )C(O)N(R y1a )\u2014, \u2014OC(O)N(R y1 )\u2014, C 1-50 alkyl, C 2-50  alkenyl, and C 2-50  alkynyl, wherein:\n -T-, C 1-20  alkyl, C 2-20  alkenyl, and C 2-20  alkynyl are optionally substituted with one or more R y2 , which are the same or different; and \n C 1-20  alkyl, C 2-20  alkenyl, and C 2-20  alkynyl are optionally interrupted by one or more groups selected from the group consisting of -T-, \u2014C(O)O\u2014, \u2014O\u2014, \u2014C(O)\u2014, \u2014C(O)N(R y3 )\u2014, \u2014S(O) 2 N(R y3 )\u2014, \u2014S(O)N(R y3 )\u2014, \u2014S(O) 2 \u2014, \u2014S(O)\u2014, \u2014N(R y3 )S(O) 2 N(R y3a )\u2014, \u2014S\u2014, \u2014N(R y3 )\u2014, \u2014OC(OR y3 ) (R y3a ), \u2014N(R y3 )C(O)N(R y3a )\u2014, and \u2014OC(O)N(R y3a )\u2014; \n wherein:\n R y1  and R y1a  are independently of each other selected from the group consisting of \u2014H, -T, C 1-10  alkyl, C 2-10  alkenyl, and C 2-10  alkynyl, wherein\n -T, C 1-10  alkyl, C 2-10  alkenyl, and C 2-10  alkynyl are optionally substituted with one or more R y2 , which are the same or different; and \n C 1-10  alkyl, C 2-10  alkenyl, and C 2-10  alkynyl are optionally interrupted by one or more groups selected from the group consisting of -T-, \u2014C(O)O\u2014, \u2014O\u2014, \u2014C(O)\u2014, \u2014C(O)N(R y4 )\u2014, \u2014S(O) 2 N(R y4 )\u2014, \u2014S(O)N(R y4 )\u2014, \u2014S(O) 2 \u2014, \u2014S(O)\u2014, \u2014N(R y4 )S(O) 2 N(R y4a )\u2014, \u2014S\u2014, \u2014N(R y4 )\u2014, \u2014OC(OR y4 )(R 4a )\u2014, \u2014N(R y4 )C(O)N(R y4a )\u2014, and \u2014OC(O)N(R y4 )\u2014; \n \n each T is independently selected from the group consisting of phenyl, naphthyl, indenyl, indanyl, tetralinyl, C 3-10  cycloalkyl, 3-membered to 10-membered heterocyclyl, 8-membered to 11-membered heterobicyclyl, 8-membered to 30-membered carbopolycyclyl, and 8-membered to 30-membered heteropolycyclyl, wherein:\n each T is independently optionally substituted with one or more R y2 , which are the same or different; \n \n R y2  is selected from the group consisting of halogen, \u2014CN, oxo (\u2550O), \u2014COOR y5 , \u2014OR y5 , \u2014C(O)R y5 , \u2014C(O)N(R y5 R y5a ), \u2014S(O) N(R y5 R y5 ), S(O)N(R y5 R y5a ), \u2014S(O) 2 R y5 , \u2014S(O)R y5 , \u2014N(R y5 ) S(O) 2 N(R y5a R y5b ), \u2014SR y5 , \u2014N(R y5 R y5a ), \u2014NO 2 , \u2014OC(O)R y5 , \u2014N(R y5 )C(O)OR y5a , \u2014N(R y5 )S(O) 2 R y5a , \u2014N(R y5 )S(O)R y5a , \u2014N(R y5 )C(O)OR y5 , \u2014N(R y5 )C(O)N(R y5a R y5b ), \u2014OC(O)N(R y5 R y5a ), and C 1-6  alkyl, wherein:\n C 1 , alkyl is optionally substituted with one or more halogen, which are the same or different; and \n \n each R y3 , R y3a , R y4 , R y4a , R y5 , R y5a , and R y5b  is, independently of each other, selected from the group consisting of \u2014H, and C 1 , alkyl; wherein:\n C 1-6  alkyl is optionally substituted with one or more halogen, which are the same or different.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 1.17391
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15027976', '14435350', '12990101', '14238437', '14650175']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8406584599124902
- 35 USC 102 Novelty (BERT): 0.5579054853865517
- Combined Prediction Score: 0.8123831624598964
- Mean Citation Score: 374.628792
- Max Citation Score: 520.1981
- Similarity Product: 312.96438109647625

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test