PATENT CLAIM ANALYSIS

Application Number: 15897947
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["514", "275000"]

Abstract:
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid form or a salt form, such as a disodium salt form, can be used to treat or alleviate pain or related conditions, such as low back pain.

Claim (Index 13):
A method of treating low back pain, comprising: 1) fasting a human being for at least one hour, wherein the human being is suffering from low back pain, followed by 2) orally administering a dosage form comprising zoledronic acid in a disodium salt form to the human being, followed by 3) fasting the human being for at least one hour;\n wherein the dosage form has bioavailability of zoledronic acid in a beagle dog that is improved by about 30% to about 200% as compared to zoledronic acid in the diacid form as determined by the following test:\n comparing the AUC 0-\u221e  obtained by orally administering the dosage form to a beagle dog to the AUC 0-\u221e  obtained by orally administering a reference dosage form containing zoledronic acid in a diacid form to the beagle dog;\n wherein the dosage form and the reference dosage form contain identical excipients with amounts of the excipients adjusted by the same molar ratio to account for the differences in molecular weights between zoledronic acid in the diacid form and zoledronic acid in the disodium salt form; \n wherein the beagle dog is fasted for two hours before the dosage form is administered and is fasted for two hours after the dosage form is administered; and \n wherein the beagle dog is fasted for two hours before the reference dosage form is administered and is fasted for two hours after the reference dosage form is administered.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 88.0
- Lexical Diversity: 1.53333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15403073', '15697267', '15416995', '15439774', '15587108']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.852688504152643
- 35 USC 102 Novelty (BERT): 0.6097744045909602
- Combined Prediction Score: 0.8283970941964747
- Mean Citation Score: 648.307588
- Max Citation Score: 676.0469
- Similarity Product: 475.3670749694349

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test