PATENT CLAIM ANALYSIS

Application Number: 15952874
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "404000"]

Abstract:
The present invention relates to cell culture media comprising inorganic ester derivatives of tyrosine and/or cysteine. The poor solubility of tyrosine and the often non-sufficient stability of cysteine in cell culture media is overcome by substituting them with an inorganic ester derivative, e.g. with a phosphorylated derivative.

Claim (Index 14):
A fed batch process for culturing cells in a bioreactor by comprising\n (i) adding cells and an aqueous cell culture medium into a bioreactor, (ii) incubating the cells in the bioreactor and (iii) feeding a cell culture feed medium continuously over the whole time of the incubation of the cells in the bioreactor or once or several times within said incubation time, to the bioreactor whereby the feed medium has a pH of less than pH 8.5 and comprises at least one phosphate or sulphate ester derivative of cysteine.)

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.37838
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14442821', '15748314', '12998494', '15534533', '15405327']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5907772562897796
- 35 USC 102 Novelty (BERT): 0.5630184260379703
- Combined Prediction Score: 0.5880013732645987
- Mean Citation Score: 265.864604
- Max Citation Score: 443.70035
- Similarity Product: 409.65077339447737

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test