PATENT CLAIM ANALYSIS

Application Number: 16012872
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "279000"]

Abstract:
Drug formulations, methods and their use in treatment of diseases using formulations of pure di-acid salts of tetrandrine family members, especially d-tetrandrine di-hydrochloride, combined with a pharmaceutical diluent or carrier.

Claim (Index 14):
A method of treating patients having malaria, and of treating in patients, and thereby reducing drug resistant multidrug resistance in the multidrug resistant strains of the following diseases: malaria,  entamoeba histolytica  (amoebic dysentery),  trypanosoma  (African sleeping sickness),  leishmania  and AIDS pneumonia, multidrug resistant protozoa, and in patients having the following multidrug resistant cancers: uterine, ovarian, breast, lymphoma, cartilage/bone, leukemia, liver, abdominal area, lung, cervical, pelvic, adrenal gland, iliac, Hodgkin's disease and thyroid cancers, and nosocomial multidrug resistance infected disease cells, comprising administering to the patient the pharmaceutical composition comprising: the pure di-acid salt of a tetrandrine family member having the following formula: where R 1  and R 1 \u2032 are the same or different short chained carbon based ligand including without limitation, CH 3 , CO 2 CH 3  or H; and R 2  is CH 3  or C 2 H 5 ; and R 3  is CH 3  or hydrogen; and a pharmaceutical carrier.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.17241
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14199235', '14025080', '14206633', '14206739', '08484469']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7195511677110552
- 35 USC 102 Novelty (BERT): 0.4972143861539123
- Combined Prediction Score: 0.6973174895553409
- Mean Citation Score: 111.19000520000002
- Max Citation Score: 134.65607
- Similarity Product: 76.10437235650599

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test