PATENT CLAIM ANALYSIS

Application Number: 15762019
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["250", "281000"]

Abstract:
A pseudo internal standard method, device and application for mass spectrometry quantitative analysis is disclosed.

Claim (Index 13):
A method of pseudo internal standard for mass spectrometry quantitative analysis, the method comprising:\n weighing a standard substance to prepare standard solutions of different concentrations using a blank substrate of a sample to be tested; then weighing the same standard substance to prepare internal standard solutions of one to a plurality of concentrations using the blank substrate of the sample to be tested; wherein an internal standard series have the same concentration range and span as said standard solutions; processing said standard solutions and said internal standard solutions of the different concentrations to standard samples and internal standard samples via sample processing steps; injecting said standard samples and said internal standard samples into a chromatography-mass spectrometry system to perform analysis and detection; plotting a ratio of detected peak areas between said standard sample and said internal standard sample versus concentrations of said standard samples to establish a calibration curve quantified by method of pseudo internal standard; and processing the unknown sample by the same sample processing steps then following the same steps as standard sample analysis to inject the sample to be detected and the internal standard into the chromatography-mass spectrometry system to perform analysis and detection, the peak area ratio of the sample over the internal standard is then compared with the calibration curve to determine the concentration of the unknown sample.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 90.0
- Lexical Diversity: 1.0
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13881848', '13379180', '15445826', '12740493', '10823691']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6808131453966718
- 35 USC 102 Novelty (BERT): 0.4989504510711137
- Combined Prediction Score: 0.6626268759641161
- Mean Citation Score: 232.221262
- Max Citation Score: 244.64362000000003
- Similarity Product: 181.2288059068716

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test