PATENT CLAIM ANALYSIS

Application Number: 15983633
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["435", "006100"]

Abstract:
A method can determine the likelihood that targeted somatic mutagenesis of a nucleic acid molecule by a mutagenic agent has occurred. The method includes analyzing the sequence of the nucleic acid molecule to determine, for a number of mutations of a mutation type at one or more motifs recognized or targeted by the mutagenic agent, the codon context of those mutations to thereby identify the location of a mutation and mutation type for each of the mutated codons in the nucleic acid molecule. The codon context of an individual mutation can be determined by determining at which of the three positions of a corresponding mutated codon the individual mutation occurs. The mutagenic agent can be one of aflatoxin, activation-induced cytidine deaminase (AID), or an apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) cytidine deaminase.

Claim (Index 6):
The method of  claim 1 , wherein the APOBEC cytidine deaminase is selected from among APOBEC1, APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3D, APOBEC3F, APOBEC3G and APOBEC3H.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 93.0
- Lexical Diversity: 1.9863
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10985321', '12911292', '13262187', '14326269', '16337461']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5669902950813307
- 35 USC 102 Novelty (BERT): 0.5181855239372568
- Combined Prediction Score: 0.5621098179669233
- Mean Citation Score: 272.25081
- Max Citation Score: 291.08972
- Similarity Product: 204.80699359622483

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test