PATENT CLAIM ANALYSIS

Application Number: 16059884
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["800", "006000"]

Abstract:
Mice are provided that comprise a reduction or deletion of ADAM6 activity from an endogenous ADAM6 locus, or that lack an endogenous locus encoding a mouse ADAM6 protein, wherein the mice comprise a sequence encoding an ADAM6 or ortholog or homolog or fragment thereof that is functional in a male mouse. In one embodiment, the sequence is an ectopic ADAM6 sequence or a sequence that confers upon a male mouse the ability to generate offspring by mating. Mice and cells with genetically modified immunoglobulin heavy chain loci that comprise an ectopic nucleotide sequence encoding a mouse ADAM6 or functional fragment or homolog or ortholog thereof are also provided.

Claim (Index 37):
The method of  claim 35 , wherein the one or more human V L  gene segments and one or more human J L  gene segments are operably linked to a mouse light chain constant region at an endogenous mouse light chain locus.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 96.0
- Lexical Diversity: 2.0
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16059871', '14192051', '14600829', '14682859', '13566765']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7256873933167164
- 35 USC 102 Novelty (BERT): 0.6696725776857978
- Combined Prediction Score: 0.7200859117536246
- Mean Citation Score: 828.1491100000003
- Max Citation Score: 866.5401
- Similarity Product: 643.4257090274334

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test