PATENT CLAIM ANALYSIS

Application Number: 16047071
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["548", "112000"]

Abstract:
The present invention is directed to compounds of the formulae I, II and III as shown below wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

Claim (Index 23):
The compound according to  claim 20  of the formula wherein\n X 1 , X 2 , X 3  and X 4  are each independently O or NH; \n R 1  and R 2  are each independently \n Z 1  is N or CR a ; Z 2  is NR b ; R a  is H, halogen, C 1-6  alkyl substituted with 0-6 R 5 , C 3-6  cycloalkyl substituted with 0-6 R 5 , CN, NO 2 , OH, OR a1 , SR a1 , \u2014C(O)NR a1 R a1 , \u2014COOR a1 , \u2014OC(O)R a1 , \u2014OC(O)NR a1 R a1 , \u2014NR a1 R a1 , \u2014NR a1 C(O)R a1 , \u2014NR a1 COOR a1 , \u2014NR a1 C(O)NR a1 R a1 , \u2014NR a1 S(O) 2 R a1 , \u2014NR a1 S(O) 2 NR a1 R a1 , \u2014S(O)R a1 , \u2014S(O)NR a1 R a1 , \u2014S(O) 2 R a1  or S(O) 2 NR a1 R a1 ; R b  is H, C 1-6  alkyl substituted with 0-6 R 5 , C 3-6  cycloalkyl substituted with 0-6 R 5 , \u2014C(O)R a1 , \u2014C(O)NR a1 R a1 , \u2014S(O) 2 R a1  or S(O) 2 NR a1 R a1 ; R a1  is H or C 1-3  alkyl; R 4  is H, CH 3 , halogen, NH 2  or OH; R 4a  is H, CH 3 , halogen, NH 2  or OH; or R 4  and R 4a  may be taken together to form a 3-4 membered carbocycle; or R 4  and R 4a  may be taken together to form a C\u2550CH 2  substituent; R 5  is H, halogen, C 1-3  alkyl, CN, NO 2 , OH, OR a1 , SR a1 , \u2014C(O)NR a1 R a1 , \u2014COOR a1 , \u2014OC(O)R a1 , \u2014OC(O)NR a1 R a1 , \u2014NR a1 R a1 , \u2014NR a1 C(O)R a1 , \u2014NR a1 COOR a1 , \u2014NR a1 C(O)NR a1 R a1 , \u2014NR a1 S(O) 2 R a1 , \u2014NR a1 S(O) 2 NR a1 R a1 , \u2014S(O)R a1 , \u2014S(O)NR a1 R a1 , \u2014S(O) 2 R a1  or S(O) 2 NR a1 R a1 ; R 5a  is H or C 1-3  alkyl; R 6  is H, halogen, C 1-3  alkyl, CN, NO 2 , OH, OR a1 , SR a1 , \u2014C(O)NR a1 R a1 , \u2014COOR a1 , \u2014OC(O)R a1 , \u2014OC(O)NR a1 R a1 , \u2014NR a1 R a1 , \u2014NR a1 C(O)R a1 , \u2014NR a1 COOR a1 , \u2014NR a1 C(O)NR a1 R a1 , \u2014NR a1 S(O) 2 R a1 , \u2014NR a1 S(O) 2 NR a1 R a1 , \u2014S(O)R a1 , \u2014S(O)NR a1 R a1 , \u2014S(O) 2 R a1  or S(O) 2 NR a1 R a1 ; R 8  is H, halogen, C 1-3  alkyl, CN, NO 2 , OH, OR a1 , SR a1 , \u2014C(O)NR a1 R a1 , \u2014COOR a1 , \u2014OC(O)R a1 , \u2014OC(O)NR a1 R a1 , \u2014NR a1 R a1 , \u2014NR a1 C(O)R a1 , \u2014NR a1 COOR a1 , \u2014NR a1 C(O)NR a1 R a1 , \u2014NR a1 S(O) 2 R a1 , \u2014NR a1 S(O) 2 NR a1 R a1 , \u2014S(O)R a1 , \u2014S(O)NR a1 R a1 , \u2014S(O) 2 R a1  or S(O) 2 NR a1 R a1 ; R 9  is H, halogen or methyl; Y is CR 5  or N; m is 0, 1, 2 or 3; n is 0 or 1; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 95.0
- Lexical Diversity: 1.32432
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12716187', '11251490', '10891362', '11787165', '14265943']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7286936809290057
- 35 USC 102 Novelty (BERT): 0.5095147997786313
- Combined Prediction Score: 0.7067757928139682
- Mean Citation Score: 262.89877
- Max Citation Score: 275.15298
- Similarity Product: 213.9634975072861

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test