PATENT CLAIM ANALYSIS

Application Number: 15915284
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "179000"]

Abstract:
Novel methods of treating tumors, including neuroendocrine tumors (NET), such as a catecholamine-secreting tumor (CST), are disclosed. The methods include treating Cushing's syndrome in a Cushing's syndrome patient having a NET, such as a CST. Tumors may be treated with a glucocorticoid receptor (GR) modulator (GRM), such as a GR antagonist (GRA). The novel treatments may treat Cushing's syndrome, may reduce catecholamine production by the tumor, may reduce catecholamine excess, may ameliorate symptoms of catecholamine excess, and may improve the efficacy of α-adrenergic or β-adrenergic blockade, somatostatin or somatostatin analog treatment or imaging, or Peptide Receptor Radionuclide Therapy, in patients with a CST. The GRM may reduce the activation of a GR, and may bind to a GR with higher affinity than it binds to a progesterone receptor (PR). In embodiments, the drug may only poorly bind to PR, or may not measurably bind to PR.

Claim (Index 3):
The method of  claim 1 , wherein said glucocorticoid receptor modulator is administered at a daily dose of between 1 and 1000 mg/kg/day.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 2.16667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15565291', '15627414', '15627359', '15570710', '15236015']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8081538615791907
- 35 USC 102 Novelty (BERT): 0.5351456930768878
- Combined Prediction Score: 0.7808530447289603
- Mean Citation Score: 332.203822
- Max Citation Score: 370.27045
- Similarity Product: 249.73119295618832

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test