PATENT CLAIM ANALYSIS

Application Number: 15781940
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-09
Patent Classification: ["424", "489000"]

Abstract:
Disclosed is a method of producing a vesicle containing a metallic nanoparticle that is covalently bound to at least one hydrophilic polymer and at least one hydrophobic polymer, wherein the method involves dispersing the polymer-bound metallic nanoparticle in an organic solvent, adding an aqueous solution containing a dispersing aid to form a mixed solution, sonicating the mixed solution to form an emulsion; and removing the organic solvent from the emulsion until the vesicle forms. Using this method, the formed vesicle has a diameter of 20-150 nm, which is useful for a method of conducting photothermal therapy (PTT) for killing cells, such as cancer cells.

Claim (Index 26):
A method of conducting photothermal therapy (PTT) comprising administering at least one vesicle of  claim 16  to a cell, and applying an external energy source to the cell that elevates the temperature to a level that induces cell death.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.74242
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14726770', '14434300', '12231310', '14215879', '14028353']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7151653768347324
- 35 USC 102 Novelty (BERT): 0.5042475142928351
- Combined Prediction Score: 0.6940735905805426
- Mean Citation Score: 233.498394
- Max Citation Score: 246.98216
- Similarity Product: 163.07456618267537

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test