PATENT CLAIM ANALYSIS

Application Number: 15760526
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "394000"]

Abstract:
The invention provides compounds and their pharmaceutical compositions according to Formula (I) that are useful for inhibiting RNA toxicity, such as in the treatment of myotonic dystrophy type 1, wherein W 1 , W 2 , W 3 , W 4 , L 1 , L 2 , and Cy are defined herein.

Claim (Index 1):
A method for treating myotonic dystrophy type 1 in a human patient suffering therefrom, comprising administering to the patient a therapeutically effective amount of a compound according to formula (I) or a pharmaceutically acceptable salt thereof: wherein W 1 , W 2 , W 3 , and W 4  are independently selected from CR 1  and N, wherein no more than one of W 1 , W 2 , W 3 , and W 4  is N; each instance of R 1  is independently selected from the group consisting of H, \u2014NR\u2032R\u2033, \u2014OR\u2032, halo, \u2014C(O)OR\u2032, \u2014C(O)R\u2032, NR\u2032C(O)R\u2033, \u2014NH\u2014C(NH)NH 2 , \u2014N\u2550CR\u2032((C 6 -C 10 )arylene)R\u2033; L 1  and L 2  are independently selected from the group consisting of a bond, (C 1 -C 8 )alkylene, \u2014NHC(O)\u2014, (C 6 -C 10 )arylene, heteroarylene;\n wherein each (C 1 -C 8 )alkylene, (C 6 -C 10 )arylene, and heteroarylene are independently and optionally substituted with one or more substituents selected from \u2014OR\u2032, halo, and \u2014NR\u2032R\u2033; \n Cy is selected from the group consisting of (C 6 -C 10 )aryl and heteroaryl;\n wherein Cy is optionally substituted with one or more substituents selected from the group consisting of \u2014NR\u2032R\u2033, \u2014OR\u2032, halo, \u2014C(O)OR\u2032, \u2014C(O)R\u2032, \u2014NR\u2032C(O)R\u2033, oxo, \u2014NHC(NH)NH 2 ; and \n R\u2032 and R\u2033 are independently selected from the group consisting of H, (C 1 -C 6 )alkyl), aryl, heteroaryl.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 90.0
- Lexical Diversity: 1.38095
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15427288', '14904999', '13851829', '14297037', '15412231']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7404970230184797
- 35 USC 102 Novelty (BERT): 0.5161168560942191
- Combined Prediction Score: 0.7180590063260537
- Mean Citation Score: 278.40387000000004
- Max Citation Score: 281.36847
- Similarity Product: 200.03427299248875

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test