PATENT CLAIM ANALYSIS

Application Number: 16204364
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["546", "273400"]

Abstract:
Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.

Claim (Index 17):
A method of preparing a piperidine compound of structural formula (VI) and pharmaceutically acceptable salts thereof, comprising:\n a step of reacting the compound represented by structural formula (XXXIII) with an alkyl halide represented by the structural formula (XII-1) or (XII-2), an epoxide represented by the structural formula (XIII), or a Weinreb amide represented by the following general structural formula (XIV): wherein m is an integer of 1 or 2; n is an integer from 0 to 2; A is selected from a phenyl group and a benzimidazole group, wherein the phenyl group is substituted with one or more groups independently selected from hydrogen, a C 1 -C 6  linear or branched alkyl group, a C 1 -C 6  linear or branched alkoxy group, an amino group, and a halogen, and the benzimidazole group is substituted with one or more groups independently selected from hydrogen, a C 1 -C 6  linear or branched alkyl group, a C 1 -C 6  linear or branched alkoxy group, a C 3 -C 7  cyclic alkyl group, an amino group, a halogen, and an oxo group; B is selected from a phenyl group, a phenoxy group, a thienyl group, and a naphthyl group, wherein the phenyl group, phenoxy group, thienyl group, or naphthyl group is substituted with one or more groups independently selected from hydrogen, halogen, nitro, cyano, methanesulfonyl, trifluoromethyl, trifluoromethoxy, difluoromethoxy, phenyl, a C 1 -C 6  linear or branched alkyl group, and a C 1 -C 6  linear or branched alkoxy group, and Z is a halogen.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 98.0
- Lexical Diversity: 1.24242
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15618252', '12576494', '14158517', '15248872', '13641867']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7668724172737339
- 35 USC 102 Novelty (BERT): 0.541874665305988
- Combined Prediction Score: 0.7443726420769593
- Mean Citation Score: 351.451378
- Max Citation Score: 385.73358
- Similarity Product: 320.79064874848365

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test