PATENT CLAIM ANALYSIS

Application Number: 15780328
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "228200"]

Abstract:
The present disclosure provides for methods for preparing tricyclic PI3K inhibitor compounds in high yield and purity in aqueous solvent systems.

Claim (Index 10):
The process of  claim 1  wherein the catalyst comprising palladium is selected from chloro(2-dicyclohexylphosphino-2\u2032,4\u2032,6\u2032-triisopropyl-1,1\u2032-biphenyl)[2-(2-aminoethyl) phenyl)]palladium(II) (\u201cPd Xphos\u201d); 1,1\u2032-bis(diphenylphosphino)ferrocene]dichloropalladium(II) complex with dichloromethane (\u201cPdCl 2  dppf CH 2 Cl 2 \u201d); Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) (\u201cPd(amphos)Cl 2 \u201d); dichlorobis(di-tert-butylphenylphosphine)palladium(II) (\u201cPd 122\u201d); PdCl 2 (PPh 3 ) 2 ; Pd(t-Bu) 3 ; Pd(PPh 3 ) 4 ; Pd(Oac)/PPh 3 ; Cl 2 Pd[(Pet 3 )] 2 ; Pd(DIPHOS) 2 ; Cl 2 Pd(Bipy); [PdCl(Ph 2 PCH 2 PPh 2 )] 2 ; Cl 2 Pd[P(o-tol) 3 ]2; Pd 2 (dba) 3 /P(o-tol) 3 ; Pd 2 (dba)/P(furyl) 3 ; Cl 2 Pd[P(furyl) 3 ] 2 ; Cl 2 Pd(PmePh 2 ) 2 ; Cl 2 Pd[P(4-F-Ph) 3 ] 2 ; Cl 2 Pd[P(C 6 F 6 ) 3 ] 2 ; Cl 2 Pd[P(2-COOH-Ph)(Ph) 2 ] 2 ; Cl 2 Pd[P(4-COOH-Ph)(Ph) 2 ] 2 ; palladium acetate, microencapsulated in a polyuria matrix, comprising 0.4 mmol/g Pd; palladium acetate and triphenylphosphine, microencapsulated in a polyuria matrix, comprising 0.4 mmol/g Pd and 0.3 mmol/g phosphorous; and palladium acetate and BINAP, microencapsulated in a polyuria matrix, comprising 0.4 mmol/g Pd.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 93.0
- Lexical Diversity: 1.1
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14524204', '14972333', '13018068', '12586241', '14930929']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7965117104107867
- 35 USC 102 Novelty (BERT): 0.5133291966858028
- Combined Prediction Score: 0.7681934590382884
- Mean Citation Score: 302.856558
- Max Citation Score: 309.51782000000014
- Similarity Product: 232.83646379713065

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test