PATENT CLAIM ANALYSIS

Application Number: 15877922
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["435", "006100"]

Abstract:
Methods and kits for prenatal genetic testing and particularly for identifying and/or analyzing fetal haplotype with a high degree of confidence are provided.

Claim (Index 2):
A method for non-invasively predicting an increased risk of a monogenic disease or disorder in a fetus of a pregnant female, the method comprising:\n (i) obtaining at least a replicate of a fetal nucleic acid sequence sequenced at a depth of at least 100\u00d7 coverage for a SNP associated with said monogenic disease or disorder, said fetal nucleic acid sequence being derived from a single DNA sample obtained from the pregnant female from week 5 of gestation and onward; and (ii) analyzing said replicate of fetal nucleic acid sequence, wherein a high identity of said fetal haplotype to a consensus family haplotype indicates that said fetus is a carrier of a parental haplotype; thereby predicting an increased risk of a monogenic disease or disorder in said fetus.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 86.0
- Lexical Diversity: 1.09091
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13313909', '12940993', '13895304', '13895308', '15214998']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6904803079813912
- 35 USC 102 Novelty (BERT): 0.56458691683613
- Combined Prediction Score: 0.6778909688668651
- Mean Citation Score: 471.949034
- Max Citation Score: 526.6980599999998
- Similarity Product: 346.15540336985697

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test