PATENT CLAIM ANALYSIS

Application Number: 16039196
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "254060"]

Abstract:
Disclosed herein are pharmaceutical compositions and dosage forms including N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino) benzamide that are useful in the treatment of subjects having cancer. The present disclosure also provides methods for preparing these pharmaceutical compositions and dosage forms, and methods of treating subjects having cancer utilizing the pharmaceutical compositions and dosage forms provided herein.

Claim (Index 26):
A pharmaceutical composition comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide, tartaric acid, anhydrous lactose, hypromellose, microcrystalline cellulose, crospovidone, colloidal silicon dioxide, and magnesium stearate, wherein the composition is prepared in a method comprising:\n adding N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide; anhydrous lactose; hypromellose; a first portion of crospovidone; and tartaric acid together and blending to form a first admixture; sieving the first admixture to form a sieved first admixture; blending the sieved first admixture to form a second admixture; sieving the second admixture to form a sieved second admixture; blending the sieved second admixture to form a third admixture; adding a first portion of magnesium stearate to the third admixture and blending to form a fourth admixture; compacting and milling the fourth admixture to form a fifth admixture; adding microcrystalline cellulose, a second portion of crospovidone, and colloidal silicon dioxide to the fifth admixture and blending to form a sixth admixture; and adding a second portion of magnesium stearate to the sixth admixture and blending to form the pharmaceutical composition.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 95.0
- Lexical Diversity: 1.53333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14623904', '14953969', '12520387', '15172478', '14528475']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7625712029953826
- 35 USC 102 Novelty (BERT): 0.5727052607593359
- Combined Prediction Score: 0.743584608771778
- Mean Citation Score: 427.776604
- Max Citation Score: 470.46823
- Similarity Product: 369.6765957889044

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test