PATENT CLAIM ANALYSIS

Application Number: 16047965
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "452000"]

Abstract:
A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.

Claim (Index 1):
A composition in the form of a dosage form, comprising:\n a) a solid amorphous dispersion comprising an active pharmaceutical ingredient and a polymer; and b) an amphiphilic material adsorbed onto a water insoluble solid excipient; wherein the amphiphilic material is a sulfonated hydrocarbon or salt thereof, a poloxamer, a polyoxyethylene alkyl ether, a polyoxyethylene sorbitan fatty acid ester, a short-chain glyceryl mono-alkylate, a polyglycolized glyceride, a mono- and di-alkylate ester of a polyol, polyoxyethylene (40 or 60) hydrogenated castor oil, polyoxyethylene (35) castor oil, alpha tocopheryl polyethylene glycol 1000 succinate, glyceryl PEG 8 caprylate/caprate, PEG 32 glyceryl laurate, a polyoxyethylene fatty acid ester, or a polyoxyethylene fatty acid ether; and wherein the water insoluble solid excipient is microcrystalline cellulose, silica, dibasic calcium phosphate, calcium silicate, clays, hydrated aluminum silicate, bentonite, hectorite, Na-, Al-, and Fe-montmorillonite, silicon dioxide, magnesium trisilicate, aluminum hydroxide, magnesium hydroxide, magnesium oxide, or talc; and wherein the solid amorphous dispersion is in the form of small particles and the amphiphilic material adsorbed onto a water insoluble solid excipient is in the form of small particles distinct from the solid amorphous dispersion particles.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 95.0
- Lexical Diversity: 1.72414
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11924988', '10910448', '13915311', '14331172', '11421888']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6857285015250464
- 35 USC 102 Novelty (BERT): 0.5603563008804318
- Combined Prediction Score: 0.6731912814605849
- Mean Citation Score: 266.93142400000005
- Max Citation Score: 419.6932
- Similarity Product: 370.6990712636472

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test