PATENT CLAIM ANALYSIS

Application Number: 15917529
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["530", "364000"]

Abstract:
A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.

Claim (Index 11):
The method according to  claim 1 , wherein the cation exchange chromatography employs a loading buffer comprising acetate buffer with a pH less than 5.0.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 90.0
- Lexical Diversity: 1.71642
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13206884', '14676727', '15707888', '15033335', '14596978']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7294654905530394
- 35 USC 102 Novelty (BERT): 0.7075900960111774
- Combined Prediction Score: 0.7272779510988532
- Mean Citation Score: 524.856532
- Max Citation Score: 812.2995599999997
- Similarity Product: 739.9741653203986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test