PATENT CLAIM ANALYSIS

Application Number: 15881806
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["210", "739000"]

Abstract:
A system for collecting MNCs to be treated with irradiation comprises a fluid circuit comprising a product container for receiving a MNC product. The system comprises a separator to work in association with the fluid circuit, the separator comprising a chamber for separation into RBCs, plasma, and an interface carrying MNCs between the RBCs and the plasma. A microprocessor-based controller is in communication with the separator, wherein the controller receives input of a target hematocrit for the MNC product. The controller also receives input for a total volume of whole blood and a number of cycles, and directs the interface and a portion of the RBCs into the product container for a resulting product volume comprising a volume of MNCs and a volume of RBCs. The controller automatically adjusts a RBC volume so that a ratio of RBCs within the MNC product to MNC product equals the target hematocrit.

Claim (Index 1):
A method for collecting diluted mononuclear cells to be treated with UV irradiation, driven and adjusted by a microprocessor-based controller, comprising the steps of:\n receiving input of a target hematocrit for a mononuclear cell product to be collected in a first container comprising mononuclear cells and red blood cells, wherein hematocrit is determined by a ratio of the red blood cells per volume within the mononuclear cell product; rotating a chamber about a rotational axis and conveying a volume of whole blood into an inlet region of the chamber for separation into a red blood cell constituent, a plasma constituent, and an interface carrying mononuclear cells between the red blood cell constituent and the plasma constituent; collecting a first volume of red blood cells in a second container, wherein the first volume of red blood cells comprises a portion of total red blood cells in the volume of whole blood; collecting a first volume of mononuclear cells, a second volume of red blood cells, and a volume of plasma in the first container, wherein the second volume of red blood cells comprises a portion of total red blood cells in the volume of whole blood; transferring a third volume of red blood cells from the second container into the first container if contents of the first container has an actual hematocrit less than the target hematocrit, wherein the third volume of red blood cells in combination with the second volume of red blood cells achieves the target hematocrit for the mononuclear cell product.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 86.0
- Lexical Diversity: 2.44615
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14758328', '15189752', '13733607', '14976950', '14828226']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8099436236619065
- 35 USC 102 Novelty (BERT): 0.5165568616126732
- Combined Prediction Score: 0.7806049474569833
- Mean Citation Score: 294.351388
- Max Citation Score: 331.71875
- Similarity Product: 249.1814967244864

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test