PATENT CLAIM ANALYSIS

Application Number: 16136953
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["424", "210100"]

Abstract:
The present application discloses methods for removing residual impurities from protein preparations. Such methods include addition of an anionic detergent to a solution comprising proteins of interest and cellular contaminants under non-precipitating conditions and passing the solution through an ion exchange column.

Claim (Index 24):
A method for producing an influenza vaccine, the method comprising the steps of:\n a. splitting a virus grown in host cells, b. adding an anionic detergent to a solution comprising viral protein of interest from the virus under non-precipitating conditions, c. passing the solution through an ion exchange matrix, whereby the residual cellular DNA is bound to the ion exchange resin, so as to obtain an eluate comprising the viral protein of interest; d. optionally further processing the eluate to provide a preparation comprising the viral protein of interest; and, e. carrying out sterile filtration of the preparation, and optionally filling and packaging.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.15789
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12199977', '14593337', '12092190', '12756590', '14699213']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6778413493322984
- 35 USC 102 Novelty (BERT): 0.4992088970559164
- Combined Prediction Score: 0.6599781041046602
- Mean Citation Score: 255.25755
- Max Citation Score: 261.4888
- Similarity Product: 200.8748181849004

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test