PATENT CLAIM ANALYSIS

Application Number: 15764071
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["546", "256000"]

Abstract:
Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.

Claim (Index 22):
The compound of  claim 21 , wherein R 2  represents aryl or heteroaryl, substituted by one or more substituents selected from the group consisting of \u2014OH, halo, \u2014NH 2 , \u2014NH((C 1 -C 6 )alkyl), \u2014N((C 1 -C 6 )alkyl) 2 , \u2014CN, \u2014NO 2 , (C 1 -C 6 )alkyl, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )alkoxy, \u2014C(O)OH, \u2014C(O)O(C 1 -C 6 )alkyl, \u2014C(O)NH 2 , \u2014C(O)NH(C 1 -C 6 )alkyl, and \u2014C(O)N((C 1 -C 6 )alkyl) 2 ; or wherein R 2  represents (halo)aryl or (halo)heteroaryl.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.575
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15123059', '15697755', '15199779', '15380836', '12774544']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8191791149916752
- 35 USC 102 Novelty (BERT): 0.5568370024834474
- Combined Prediction Score: 0.7929449037408525
- Mean Citation Score: 377.365504
- Max Citation Score: 445.71603
- Similarity Product: 321.819833240093

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test