PATENT CLAIM ANALYSIS

Application Number: 15959589
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["424", "489000"]

Abstract:
The disclosure provides macrolide particulates including a macrolide therapeutic agent such as rapamycin at high concentration in the particulate. In one method the particulates are made by adding a composition containing an polyoxyethylene sorbitan n-acyl ester, poly(ethyleneimine), or alkylated quaternary ammonium salt to a composition including macrolide dissolved in an alcohol such as ethanol. In another method the particulates are made by adding a non-solvent composition to a composition including macrolide and an alkyl-substituted chromanol dissolved in an alcohol such as ethanol. The formed macrolide particulates have one or more desirable properties including sizes in the range of 0.1 μm to 10 μm, spherical or near spherical shapes, low polydispersity, and/or stability. The macrolide particulates can be used for therapeutic compositions, or in association with an implantable or insertable medical device, such as associated with a polymeric coating on a device.

Claim (Index 32):
The balloon catheter of  claim 31  wherein the macrolide therapeutic agent is present in an amount of 99% or greater, of the weight of the particulate.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 1.83529
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14280054', '15262465', '14303309', '15474487', '14880332']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7882995783473783
- 35 USC 102 Novelty (BERT): 0.5810067583760298
- Combined Prediction Score: 0.7675702963502435
- Mean Citation Score: 394.453436
- Max Citation Score: 566.1743
- Similarity Product: 374.933228008616

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test