PATENT CLAIM ANALYSIS

Application Number: 16171124
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-06
Patent Classification: ["546", "069000"]

Abstract:
Provided herein are ergoline compounds and pharmaceutical compositions thereof. In some embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT 1A , 5-HT 1B  and 5-HT 1D  receptors without agonizing the 5-HT 2B  receptor using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the 5-HT 2B  adrenergic alpha 2A  and/or the alpha 2B  receptors using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the D2 and D3 receptor using the compounds and pharmaceutical compositions disclosed herein.

Claim (Index 24):
A method of treating or preventing migraine, comprising administering to a subject in need thereof a compound represented by structural Formula (VIII): or a salt thereof, wherein:\n R 1  is cycloalkyl; \n R 3  is hydrogen or alkyl; \n R 4  and R 5  are independently hydrogen, halo, \u2014OR 120 , \u2014OC(O)NR 121 R 122 , \u2014OC(O)R 123  or together with the atoms to which they are attached form a double bond; \n R 6  and R 7  are independently hydrogen, alkyl or substituted alkyl; \n R 8  is alkyl; \n R 120  is hydrogen or alkyl; \n R 121 , R 122  are independently hydrogen or alkyl; and \n R 123  is alkyl.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 97.0
- Lexical Diversity: 2.86275
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15943714', '16016474', '15001252', '15448951', '15449018']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8091741377049642
- 35 USC 102 Novelty (BERT): 0.5270847262991827
- Combined Prediction Score: 0.780965196564386
- Mean Citation Score: 362.98652
- Max Citation Score: 375.36508
- Similarity Product: 298.73621512792346

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test