PATENT CLAIM ANALYSIS

Application Number: 15925172
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "04400R"]

Abstract:
The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.

Claim (Index 35):
A method of providing a regenerative effect to a native kidney comprising in vivo contacting the native kidney with a composition comprising isolated human secreted vesicles produced by an enriched renal cell population, wherein the vesicles comprise a paracrine factor that attenuates Plasminogen Activation Inhibitor-1 (PAI-1) signaling and/or Transforming Growth Factor Beta (TGF\u03b2) signaling, wherein the vesicles have been isolated from the renal cell population, and wherein the regenerative effect comprises a reduction in renal fibrosis.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 90.0
- Lexical Diversity: 1.15789
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13697206', '13883433', '14945283', '13661668', '12617721']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7493377989042921
- 35 USC 102 Novelty (BERT): 0.6484372267353711
- Combined Prediction Score: 0.7392477416874
- Mean Citation Score: 431.2569500000001
- Max Citation Score: 607.6384
- Similarity Product: 588.5018216161727

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test