PATENT CLAIM ANALYSIS

Application Number: 15865703
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-09
Patent Classification: ["544", "139000"]

Abstract:
This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer.

Claim (Index 1):
A method for treating a susceptible neoplasm in a mammal in need thereof comprising the steps of:\n (a) analyzing a sample from said neoplasm to determine whether there is a PTEN deficiency in cells of said neoplasm; (b) selecting a mammal having said neoplasm with PTEN deficiency; and (c) administering a therapeutically effective amount the compound of formula or a pharmaceutically acceptable salt thereof to the mammal selected in step (b).

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.71233
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14712991', '14164414', '13251476', '13798923', '14844051']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7526829628138825
- 35 USC 102 Novelty (BERT): 0.4870422812805035
- Combined Prediction Score: 0.7261188946605446
- Mean Citation Score: 271.152424
- Max Citation Score: 271.29883
- Similarity Product: 268.5058318102169

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test