PATENT CLAIM ANALYSIS

Application Number: 15904993
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["514", "210010"]

Abstract:
Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Claim (Index 23):
The method of  claim 1 , wherein the compound is any one of Compound Numbers 14, 94, 97, 98, 99, 100, 105, 119, 143, 159, 164, 165, 224, 225, 226, 230, 233, 301, 308, 318, 342, 344, 355, 370, 379, 424, 474, 479, 537, 577, 581, 586, 601, 638, 661, 665, 668, 684, 703, 761, 801, 806, 811, 812, 870, 880, 890, 918, 924, 925 928, 945, 953, 957, 958, 959, 966, 968, 969, 970, 974, 978, 979, 986, 990, 994, 998, 999, 1000, 1001, 1005, 1007, 1009, 1010, 1011, 1012, 1013, 1014, 1015, 1016, 1017, 1018, 1020, 1024, 1025, 1026, 1027, 1028, 1029, 1030, 1031, 1032, 1033, 1034, 1035, 1036, 1046, 1047, 1048, 1049, 1050, 1060, 1062, 1063, 1064, 1066, 1069, 1071, 1072, 1073, 1074, 1077, 1080, 1081, 1082, 1083, 1085, 1086, 1087, 1092, 1096 and 1098.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 88.0
- Lexical Diversity: 1.47143
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12999795', '12990339', '15528195', '13504134', '13121411']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8176645642572681
- 35 USC 102 Novelty (BERT): 0.5371932518824081
- Combined Prediction Score: 0.7896174330197822
- Mean Citation Score: 370.57483
- Max Citation Score: 381.78717
- Similarity Product: 228.71967965363143

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test