PATENT CLAIM ANALYSIS

Application Number: 15903744
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["435", "135000"]

Abstract:
This document describes biochemical pathways for producing 2,4-pentadienoyl-CoA by forming one or two terminal functional groups, comprised of carboxyl or hydroxyl group, in a C5 backbone substrate such as glutaryl-CoA, glutaryl-[acp] or glutarate methyl ester. 2,4-pentadienoyl-CoA can be enzymatically converted to 1,3-butadiene.

Claim (Index 43):
The method of  claim 23 , wherein the method is performed in a host comprises comprising an attenuation of one or more polypeptides having an activity selected from the group consisting of: polyhydroxyalkanoate synthase, an acetyl-CoA thioesterase, an acetyl-CoA specific \u03b2-ketothiolase, an acetoacetyl-CoA reductase, a phosphotransacetylase forming acetate, an acetate kinase, a lactate dehydrogenase, a menaquinol-fumarate oxidoreductase, a 2-oxoacid decarboxylase producing isobutanol, an alcohol dehydrogenase forming ethanol, a triose phosphate isomerase, a pyruvate decarboxylase, a glucose-6-phosphate isomerase, a transhydrogenase dissipating the cofactor imbalance, aglutamate dehydrogenase specific for the co-factor for which an imbalance is created, a NADH/NADPH-utilizing glutamate dehydrogenase, a pimeloyl-CoA dehydrogenase; an acyl-CoA dehydrogenase accepting C5 building blocks and central precursors as substrates; a glutaryl-CoA dehydrogenase; and a pimeloyl-CoA synthetase.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.13636
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14741414', '14741259', '14740554', '14139072', '14740749']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6150853992939334
- 35 USC 102 Novelty (BERT): 0.7136981432450783
- Combined Prediction Score: 0.6249466736890479
- Mean Citation Score: 625.527602
- Max Citation Score: 844.33905
- Similarity Product: 755.0516343986212

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test