PATENT CLAIM ANALYSIS

Application Number: 15753865
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-05
Patent Classification: ["514", "04400A"]

Abstract:
Provided herein are methods for the treatment of poly-cystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.

Claim (Index 14):
The method of  claim 1 , wherein the administering:\n a) reduces albuminuria in the subject; b) slows the worsening of albuminuria in the subject; c) delays the onset of albuminuria in the subject; d) reduces hematuria in the subject; e) slows the worsening of hematuria in the subject; f) delays the onset of hematuria in the subject; g) reduces blood urea nitrogen in the subject; h) reduces creatinine in the blood of the subject; i) improves creatinine clearance in the subject; j) reduces albumin:creatinine ratio in the subject; k) improves glomerular filtration rate in the subject; l) slows the worsening of glomerular filtration rate in the subject; m) reduces neutrophil gelatinase-associated lipocalin (NGAL) protein in the urine of the subject; and/or n) reduces kidney injury molecule-1 (KIM-1) protein in the urine of the subject.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 88.0
- Lexical Diversity: 1.13043
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14048827', '14872564', '15380629', '13811423', '14334872']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.822601501372742
- 35 USC 102 Novelty (BERT): 0.5421872409637282
- Combined Prediction Score: 0.7945600753318407
- Mean Citation Score: 364.996002
- Max Citation Score: 393.703
- Similarity Product: 299.6162109277248

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test