PATENT CLAIM ANALYSIS

Application Number: 16075110
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "293000"]

Abstract:
The present application present application relates to a compound represented by Formula (III) or a pharmaceutically acceptable salt, solvent compound, active metabolite, crystal polymorph, ester, isomer, or prodrug thereof. The application further provides a pharmaceutical composition comprising the compound represented by Formula (III) and a use thereof for preparing a bromodomain inhibitor for preventing or treating various diseases, such as inflammation and cancer, related to the bromodomain.

Claim (Index 23):
The compound or a pharmaceutically acceptable salt, solvate, active metabolite, polymorph, ester, isomer or prodrug thereof according to  claim 21 , wherein\n R 1  is selected from the group consisting of halogen, \u2014CN, \u2014OH, \u2014NH 2 , \u2014NH\u2014C 1-6  alkyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)\u2014C 1-6  alkyl, \u2014C(\u2550O)N(CH 3 )\u2014OCH 3 , \u2014C(\u2550O)NH\u2014C 1-6  alkyl, \u2014COOH, \u2014C(\u2550O)O\u2014C 1-6  alkyl, C 1-6  alkyl, C 2-6  alkenyl, \u2014C 1-6  alkoxy, C 3-8  cycloalkyl, 3- to 8-membered heterocycloalkyl containing 1-3 heteroatoms independently selected from the group consisting of N, O and S, \u2014SO 2 \u2014C 1-6  alkyl, \u2014NHSO 2 \u2014C 1-6  alkyl and \u2014N(SO 2 \u2014C 1-6  alkyl) 2 , wherein the alkyl, alkenyl, cycloalkyl and heterocycloalkyl may be optionally substituted by \u2014F, \u2014Cl, \u2014Br, \u2014OH or \u2014NH 2 ; preferably, R 1  is selected from the group consisting of \u2014OH, \u2014NH 2 , \u2014NH\u2014C 1-6  alkyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)\u2014C 1-6  alkyl, \u2014C(\u2550O)NH\u2014C 1-6  alkyl, \u2014COOH, \u2014C(\u2550O)O\u2014C 1-6  alkyl, C 1-6  alkyl, C 2-6  alkenyl, C 1-6  alkoxy, C 3-8  cycloalkyl, 3- to 8-membered heterocycloalkyl containing 1-3 heteroatoms independently selected from the group consisting of N, O and S, \u2014SO 2 \u2014C 1-6  alkyl, \u2014NHSO 2 \u2014C 1-6  alkyl and \u2014N(SO 2 \u2014C 1-6  alkyl) 2 , wherein the alkyl, alkenyl, cycloalkyl and heterocycloalkyl may be optionally substituted by \u2014F, \u2014Cl, \u2014Br, \u2014OH or \u2014NH 2 ; more preferably, R 1  is selected from the group consisting of \u2014OH, \u2014NH 2 , \u2014NH\u2014C 1-6  alkyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)\u2014C 1-6  alkyl, \u2014C(\u2550O)NH\u2014C 1-6  alkyl, \u2014COOH, \u2014C(\u2550O)O\u2014C 1-6  alkyl, C 1-6  alkyl, C 2-6  alkenyl, C 1-6  alkoxy, \u2014SO 2 \u2014C 1-6  alkyl, \u2014NHSO 2 \u2014C 1-6  alkyl and \u2014N(SO 2 \u2014C 1-6  alkyl) 2 , wherein the alkyl and alkenyl may be optionally substituted by \u2014F, \u2014Cl, \u2014Br, \u2014OH or \u2014NH 2 ; and further preferably, R 1  is selected from the group consisting of \u2014F, \u2014OH,

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.65306
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15305384', '14819541', '14072563', '14207868', '14846545']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8410719706116854
- 35 USC 102 Novelty (BERT): 0.5304957884897178
- Combined Prediction Score: 0.8100143523994886
- Mean Citation Score: 362.686824
- Max Citation Score: 366.06772
- Similarity Product: 274.0005063356304

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test