PATENT CLAIM ANALYSIS

Application Number: 16066852
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "450000"]

Abstract:
Disclosed in the present disclosure is a Dezocine analogue, and particularly disclosed are compounds represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof.

Claim (Index 1):
A compound represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof, wherein, each of X 1 , X 2 , X 3  is independently selected from single bond, CH 2 , C(RR), NH, N(R), O, or S; R 12  is selected from H, F, Cl, Br, I, CN, OH, NH 2 , or the group consisting of C 1-6  alkyl or heteroalkyl, 3-7 membered cycloalkyl or heterocycloalkyl, 5-7 membered aryl or heteroaryl, each of which is optionally substituted by 1, 2, or 3 R; and, when X is CH 2 , R 12  is not H; each of R 22  and R 32  is independently selected from H, F, Cl, Br, I, CN, OH, NH 2 , or the group consisting of C 1-6  alkyl or heteroalkyl, 3-7 membered cycloalkyl or heterocycloalkyl, and 5-7 membered aryl or heteroaryl, each of which is optionally substituted by 1, 2, or 3 R; n is 1, 2, or 3; each of R 11 , R 21  and R 31  is independently selected from the group consisting of C 1-6  alkyl and C 1-6  heteroalkyl, each of which is optionally substituted by 1, 2, or 3 R; R 23  is selected from the group consisting of C 1-12  alkyl, C 1-12  heteroalkyl, C 3-7  cycloalkyl, and 3-7 membered heterocycloalkyl, each of which is optionally substituted by 1, 2, or 3 R; L is selected from the group consisting of C 1-12  alkyl, C 1-12  heteroalkyl, C 3-7  cycloalkyl, or 3-7 membered heterocycloalkyl, each of which is optionally substituted by 1, 2, or 3 R; said \u201chetero\u201d represents O, S, or N, the number of which is selected from 1, 2 or 3 in any of the above cases; said R is selected from F, Cl, Br, I, CN, OH, NH 2 , C 1-3  alkyl, or C 1-3  heteroalkyl; said C 1-3  alkyl or C 1-3  heteroalkyl are each optionally substituted by 1, 2, or 3 substituents selected from the group consisting of F, Cl, Br, I, CN, OH, NH 2 ; two geminal or ortho R optionally connect to the same atom forming 3-6 membered cycloalkyl or heterocycloalkyl.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 94.0
- Lexical Diversity: 1.26667
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16093376', '16087861', '15750704', '16325626', '16326976']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8278195934239274
- 35 USC 102 Novelty (BERT): 0.5624430910205134
- Combined Prediction Score: 0.801281943183586
- Mean Citation Score: 424.76278
- Max Citation Score: 435.91037
- Similarity Product: 363.6065877365977

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test