PATENT CLAIM ANALYSIS

Application Number: 15769520
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "235500"]

Abstract:
The present invention relates to substituted morpholine derivatives having pharmacological activity towards the sigma (σ) receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

Claim (Index 33):
A process for the preparation of the compound of Formula (I) according to  claim 17 , employing a compound of Formula Ia, II, IIP, III, IIIP, IV, V, VP, VI, VII, VIIP, VIIIP, VIIIH, IX, X, XI, XII, XIIP, XIII, XIIIP, XIIIH, XIV, XIVP, XV, XVP, XVI, XVIP, XVIH, Ib, XVIIP, XVIIH, Ic, XVIIIP, Id, XIXP, XIXH, Ie, XXP, XXH, XXI, XXIP, XXIH, XXII, XXIIP, XXIIH, XXIII, XXIIIP, XXIIIH, XXIV, XXIVP, XXIVH, XXV, XXVP, XXVH, If, XXVIP, XXVIH, XXVIIa, XXVIIb, XXVIIc, Ig, XXVIIIP, XXVIIIH, Ih, XXIXP, XXIXH, Ii, XXXP, XXXH, XXXI, XXXIP, XXXIH, XXXII, XXXIIP, XXXIIH, XXXIII, XXXIIIP, XXXIIIH, XXXIV, XXXIVP, XXXIVH, XXXV, Ij, XXXVIP or XXXVIH, wherein R 1\u2032 , R 2 , R 3 , R 3\u2032 , R 4 , R 4\u2032 , R 5 , R 5\u2032 , R 6 , R 6\u2032 , R 7 , R 8 , R 9 , R 10 , R x , R x\u2032 , X, Y, m, n, p, q and r have the meanings as defined in  claim 17  for the compound of Formula (I), LG represents a leaving group, including halogen, mesylate, tosylate and triflate, with the proviso that when Y\u2550CO, LG represents chloro or bromo, W represents an aldehyde or another leaving group, including halogen, mesylate, tosylate and triflate, P represents a suitable protecting group, including Boc, P\u2032 represents an orthogonal protecting group, including 4-methoxybenzyl and benzyl, Q represents methyl or benzyl, X\u2032 represents a leaving group, including halogen, mesylate, tosylate and triflate, and Z represents OH or halogen, including bromo and chloro.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 1.26316
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15769754', '15769502', '15746877', '15747220', '15569939']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8582953463594603
- 35 USC 102 Novelty (BERT): 0.6556343476024799
- Combined Prediction Score: 0.8380292464837622
- Mean Citation Score: 553.929814
- Max Citation Score: 679.1681
- Similarity Product: 602.9225949077247

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test