PATENT CLAIM ANALYSIS

Application Number: 16201117
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-08
Patent Classification: ["546", "200000"]

Abstract:
The invention provides novel asymmetric and symmetric bisaminoquinolmes and related compounds, methods of treatment and syntheses. The novel compounds exhibit effective anticancer activity and are useful in the treatment of a variety of autophagy-related disorders.

Claim (Index 27):
The method according to  claim 26 , wherein said leukemia is acute myelogenous leukemia, acute lymphocytic leukemia, acute promyelocytic leukemia (APL), acute T-cell lymphoblastic leukemia, adult T-cell leukemia, basophilic leukemia, eosinophilic leukemia, granulocytic leukemia, hairy cell leukemia, leukopenic leukemia, lymphatic leukemia, lymphoblastic leukemia, lymphocytic leukemia, megakaryocytic leukemia, micromyeloblastic leukemia, monocytic leukemia, neutrophilic leukemia and stem cell leukemia, said lymphoma is Burkitt's lymphoma, Non-Hodgkin's lymphoma or B-cell lymphoma, said sarcoma is Ewing's sarcoma, hemangiosarcoma, Kaposi's sarcoma, liposarcoma, myosarcomas, peripheral neuroepithelioma or synovial sarcoma, said tumor of the central nervous system is a glioma, astrocytoma, oligodendroglioma, ependymoma, glioblastoma, neuroblastoma, ganglioneuroma, ganglioglioma, medulloblastoma, pineal cell tumor, meningioma, meningeal sarcoma, neurofibroma, or Schwannoma, said germ-line tumor is bowel cancer, breast cancer, prostate cancer, cervical cancer or uterine cancer, said lung cancer is small cell lung cancer, mixed small cell and non-small cell cancer, pleural mesothelioma, metastatic pleural mesothelioma, small cell lung cancer or non-small cell lung cancer, said mixed neoplasia is carcinosarcoma and Hodgkin's disease and said tumors of mixed origin is Wilms' tumor and teratocarcinomas, said cancer is ovarian, breast, colon, head and neck, medulloblastoma or B-cell lymphoma, said cancer is melanoma or non-small cell lung cancer.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 98.0
- Lexical Diversity: 1.35714
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15502330', '15384823', '15890040', '15580978', '14396956']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7911468869672266
- 35 USC 102 Novelty (BERT): 0.6196599379699175
- Combined Prediction Score: 0.7739981920674956
- Mean Citation Score: 356.153908
- Max Citation Score: 619.825
- Similarity Product: 503.6478602826596

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test