PATENT CLAIM ANALYSIS

Application Number: 15958586
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "243000"]

Abstract:
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

Claim (Index 1):
A compound of formula I\u2032: or a pharmaceutically acceptable salt thereof, wherein: Ring A is selected from: each p is independently 0, 1, or 2, as valency will allow; each R 1  is independently selected from R, \u2014C(O)R, \u2014C(O)OR, \u2014SO 2 R, \u2014C(O)N(R) 2 , or \u2014SO 2 RN(R) 2 ; each R is independently hydrogen, deuterium, or an optionally substituted group selected from C 1-6  aliphatic, a 3-8 membered saturated or partially unsaturated monocyclic carbocyclic ring, phenyl, an 8-10 membered bicyclic aromatic carbocyclic ring; a 4-8 membered saturated or partially unsaturated monocyclic heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered monocyclic heteroaromatic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-10 membered bicyclic heteroaromatic ring having 1-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or two R on the same nitrogen are taken together with their intervening atoms to form a 4-7 membered saturated, partially unsaturated, or aromatic ring having 1-2 heteroatoms in addition to the nitrogen independently selected from oxygen, nitrogen, or sulfur; each or R x , R y , and R z  is independently selected from R, halogen, cyano, nitro, \u2014OR, \u2014SR, \u2014N(R) 2 , \u2014N(R)C(O)R, \u2014C(O)N(R) 2 , \u2014C(O)N(R)OR, \u2014N(R)C(O)N(R) 2 , N(R)C(O)OR, \u2014OC(O)N(R) 2 , \u2014N(R)SO 2 R, \u2014SO 2 RN(R) 2 , \u2014C(O)R, \u2014C(O)OR, \u2014OC(O)R, \u2014C(O)OR, \u2014S(O)R, or \u2014SO 2 R, or:\n two R x  on the same carbon are taken together to form \u2550O or \u2550S; or: \n two R y  on the same carbon are taken together to form \u2550O or \u2550S; \n each of m and n is independently 1, 2, 3, 4, or 5; Ring B is phenyl, a 7-10 membered bicyclic partially unsaturated or aromatic carbocyclic ring, a 5-6 membered monocyclic heteroaromatic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, an 8-10 membered bicyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 12-15 membered partially unsaturated or aromatic tricyclic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; Ring C is phenyl or a 5-6 membered heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; L 1  is a covalent bond or an optionally substituted C 1-6  membered straight or branched bivalent hydrocarbon chain wherein a methylene unit of L 1  is optionally replaced with -Cy-, \u2014O\u2014, \u2014S\u2014, \u2014NR\u2014, \u2014C(O)\u2014, \u2014C(O)O\u2014, \u2014OC(O)\u2014, \u2014C(O)N(R)\u2014, \u2014N(R)C(O)\u2014, \u2014SO 2 \u2014, \u2014N(R)SO 2 \u2014, or \u2014SO 2 N(R)\u2014S; and -Cy- is a 3-8 membered bivalent saturated, partially unsaturated, or aromatic monocyclic ring having 0-2 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-10 membered bivalent saturated, partially unsaturated, or aromatic bicyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur; with the proviso that when Ring A is Ring B is not and/or Ring C is not and/or R 1  is not

Metadata:
- Claim Count in Document: 23.0
- Percentile: 91.0
- Lexical Diversity: 1.10526
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13882449', '14596052', '15698171', '13393192', '13499835']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7804705274883971
- 35 USC 102 Novelty (BERT): 0.4982689246735218
- Combined Prediction Score: 0.7522503672069095
- Mean Citation Score: 261.577766
- Max Citation Score: 263.09778
- Similarity Product: 213.3950982294845

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test