PATENT CLAIM ANALYSIS

Application Number: 15901503
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["558", "413000"]

Abstract:
The invention relates to novel chemical entities that act as thromboxane (TX) A 2  receptor, or T prostanoid receptor (TP), antagonists and to their use in the treatment of human diseases in which thromboxane (TX) A and of all other agents that act as incidental ligands of TP, including the endoperoxide prostaglandin (PG)G 2 /PGH 2 , 20-hydroxyeicosatetraenoic acid (20-HETE) and the free-radical derived isoprostanes (e.g., 8-iso-prostaglandin (PG)F 2α ), play a role. Compounds of the invention preferably include a benzenesulfonyl urea in which the benzene is substituted by a substituted biphenylyloxy group (e.g., at the 2 position) and by a nitrile group (e.g., at the 5 position), which compounds show promising results as TP-isoform selective TP antagonists.

Claim (Index 4):
The method of  claim 2 , wherein\n R 1  is selected from the group consisting of: a difluoromethyl group, a halogenated methoxy group, a primary amide, a secondary amide, a tertiary amide, and a nitrile group; and R 2  is selected from the group consisting of an alkyl group of 3 to 6 carbons, and a halogenated alkyl group of 3 to 6 carbons, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 33.0
- Percentile: 88.0
- Lexical Diversity: 1.86076
- Patent Class: 558.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15180805', '14391856', '15460910', '15349379', '15178931']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.817329325150807
- 35 USC 102 Novelty (BERT): 0.7120413815493764
- Combined Prediction Score: 0.8068005307906639
- Mean Citation Score: 586.388146
- Max Citation Score: 777.21484
- Similarity Product: 705.2025988460922

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test