PATENT CLAIM ANALYSIS

Application Number: 15756867
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["514", "253040"]

Abstract:
The present application relates to novel 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.

Claim (Index 4):
A process for preparing a compound of the formula (I) according to  claim 1 , characterized in that a compound of the formula (II) in which R 1  is as defined in  claim 1 is reacted in the presence of a suitable reducing agent either [A] with a compound of the formula (III) in which R 2  is as defined in  claim 1 or [B] with a protected piperazine derivative of the formula (IV) in which PG represents a suitable amino protective group such as, for example, tert-butoxycarbonyl, benzyloxycarbonyl or (9H-fluoren-9-ylmethoxy)carbonyl, to give initially a compound of the formula (V) in which PG and R 1  have the meanings given above, the protective group PG is then removed and the resulting compound of the formula (VI) in which R 1  has the meaning given above is then reacted with a carboxylic acid of the formula (VII) in which R 2  is as defined in  claim 1 with activation of the carboxylic acid function in (VII) or is reacted with the corresponding acid chloride of the formula (VIII) in which R 2  is as defined in  claim 1 and the resulting compounds of the formula (I) are optionally converted with the appropriate (i) solvents and/or (ii) acids into their solvates, salts and/or solvates of the salts.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 90.0
- Lexical Diversity: 1.64583
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15781848', '15032212', '14414297', '15552997', '15600132']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8167917435649736
- 35 USC 102 Novelty (BERT): 0.5233792693343954
- Combined Prediction Score: 0.7874504961419159
- Mean Citation Score: 321.642714
- Max Citation Score: 341.45038
- Similarity Product: 306.209295710516

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test