PATENT CLAIM ANALYSIS

Application Number: 15874144
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "054000"]

Abstract:
The present invention relates to a crosslinked hyaluronic acid gel which derives from the crosslinking of hyaluronic acid or of a salt thereof in the presence of at least an effective amount of at least one endogenous polyamine as a crosslinking agent, said crosslinking being carried out under conditions favourable to the coupling of said hyaluronic acid and of said endogenous polyamine(s).

Claim (Index 1):
A process for preparing a crosslinked gel of hyaluronic acid or a salt thereof, comprising at least the steps:\n a) providing an aqueous gel of hyaluronic acid or of a salt thereof, in the noncrosslinked state, b) bringing the gel obtained in step a) into contact with an effective amount of at least one endogenous polyamine, wherein said at least one endogenous polyamine is used in a content between 0.1% and 3% by number of moles of the at least one endogenous polyamine relative to the number of moles of hyaluronic acid, c) crosslinking said mixture formed in step b), said crosslinking being carried out under conditions favourable to the covalent coupling of said hyaluronic acid and of said at least one endogenous polyamine(s), and d) recovering said crosslinked hydrogel, wherein said crosslinked hydrogel has a degree of modification of less than or equal to 1%, the degree of modification being the ratio between the number of moles of endogenous polyamine attached to the hyaluronic acid and the number of moles of hyaluronic acid forming said crosslinked gel.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 86.0
- Lexical Diversity: 1.48889
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14437917', '15705809', '15536039', '15214983', '13954360']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7520672851293013
- 35 USC 102 Novelty (BERT): 0.5197561185082039
- Combined Prediction Score: 0.7288361684671916
- Mean Citation Score: 242.140596
- Max Citation Score: 335.83466
- Similarity Product: 304.3140894402861

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test