PATENT CLAIM ANALYSIS

Application Number: 15966513
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
Methods and techniques to increase the reliability of detecting virus infections, particularly lymphotropism, to eliminate false negative reactions in testing blood for the presence of lymphotropic viruses during enzyme immunoassay (EIA) and polymerase chain reaction (PCR) testing, and to better detect viruses with lymphotropism in biological materials having a concentration of virus particles lower than the sensitivity threshold of existing EIA and PCR methods, thereby making the techniques of the present invention more reliable.

Claim (Index 1):
A method for the detection of viruses with lymphotropism properties in a biological material with a low virus concentration, comprising:\n forming an admixture of an equal amount of a biological material from a patient with a lymphocyte suspension from a healthy human subject; incubating the admixture; washing-out the lymphocytes in the admixture; removing lymphocyte membranes from the admixture, separating the lymphocyte cytoplasm content; and detecting the presence or absence of the virus RNA or DNA in the lymphocyte cytoplasm content, wherein the presence of the virus RNA or DNA in the lymphocyte cytoplasm content indicates the preserved viability of viruses in said biological sample of said patient, wherein the absence of the virus RNA or in the lymphocyte cytoplasm content indicates the loss of virus viability in said biological sample of said patient, and wherein said low virus concentration is below enzyme immunoassay (EIA) and polymerase chain reaction (PCR) testing sensitivity thresholds.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 1.45614
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15257663', '14397680', '15342471', '14889370', '15608300']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7697718457141699
- 35 USC 102 Novelty (BERT): 0.5994476416812506
- Combined Prediction Score: 0.752739425310878
- Mean Citation Score: 414.689924
- Max Citation Score: 576.5979
- Similarity Product: 453.9525656405925

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test