PATENT CLAIM ANALYSIS

Application Number: 15970128
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "235800"]

Abstract:
The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.

Claim (Index 2):
The pharmaceutical composition according to  claim 1 , wherein the HBV capsid assembly inhibitor is a compound of formula (I): wherein\n R 1  is C 1-6 alkyl or trifluoromethyl-C x H 2x -, wherein x is 1, 2, 3, 4, 5 or 6; \n One of R 2  and R 3  is phenyl, which is once or twice or three times substituted by C 1-6 alkyl, cyano or halogen; and the other one is hydrogen or deuterium; \n R 4  is phenyl, thiazolyl, oxazolyl, imidazolyl, thienyl or pyridinyl, which is unsubstituted or substituted by C 1-6  alkyl, C 1-6 alkylsulfanyl, halogen or cycloalkyl, wherein C 1-6  alkyl can be further optionally substituted with halogen; \n A is \n which is unsubstituted or substituted by groups selected from C 1-6 alkyl, deuterium and halogen; or pharmaceutically acceptable salt, or enantiomer, or diastereomer thereof.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 93.0
- Lexical Diversity: 1.38889
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14640397', '14946595', '14279716', '14991786', '14839376']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8085466847774809
- 35 USC 102 Novelty (BERT): 0.6767389758284574
- Combined Prediction Score: 0.7953659138825786
- Mean Citation Score: 514.621874
- Max Citation Score: 716.02423
- Similarity Product: 636.3045346910084

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test