PATENT CLAIM ANALYSIS

Application Number: 16148822
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "04400A"]

Abstract:
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

Claim (Index 1):
A compound of Formula (I): or its N-oxide,\n or a salt or isomer thereof, wherein R 1  is selected from the group consisting of C 5-30  alkyl, C 5-20  alkenyl, \u2014R*YR\u2033, \u2014YR\u2033, and \u2014R\u2033M\u2032R\u2032; \n R 2  and R 3  are independently selected from the group consisting of H, C 1-14  alkyl, C 2-14  alkenyl, \u2014R*YR\u2033, \u2014YR\u2033, and \u2014R*OR\u2033, or R 2  and R 3 , together with the atom to which they are attached, form a heterocycle or carbocycle; \n each R 5  is independently selected from the group consisting of C 1-3  alkyl, C 2-3  alkenyl, and H; \n each R 6  is independently selected from the group consisting of C 1-3  alkyl, C 2-3  alkenyl, and H; \n M and M\u2032 are independently selected from \u2014C(O)O\u2014, \u2014OC(O)\u2014, \u2014OC(O)-M\u2033-C(O)O\u2014, \u2014C(O)N(R\u2032)\u2014, \u2014N(R\u2032)C(O)\u2014, \u2014C(O)\u2014, \u2014C(S)\u2014, \u2014C(S)S\u2014, \u2014SC(S)\u2014, \u2014CH(OH)\u2014, \u2014P(O)(OR\u2032)O\u2014, \u2014S(O) 2 \u2014, \u2014S\u2014S\u2014, an aryl group, and a heteroaryl group, in which M\u2033 is a bond, C 1-13  alkyl or C 2-13  alkenyl; \n R 7  is selected from the group consisting of C 1-3  alkyl, C 2-3  alkenyl, and H; \n each R is independently selected from the group consisting of H, C 1-3  alkyl, and C 2-3  alkenyl; \n each R\u2032 is independently selected from the group consisting of C 1-18  alkyl, C 2-18  alkenyl, \u2014R*YR\u2033, \u2014YR\u2033, and H; \n each R\u2033 is independently selected from the group consisting of C 3-15  alkyl and C 3-15  alkenyl; \n each R* is independently selected from the group consisting of C 1-12  alkyl and C 2-12  alkenyl; \n each Y is independently a C 3-6  carbocycle; \n each X is independently selected from the group consisting of F, Cl, Br, and I; \n R 10  is selected from the group consisting of NH 2 , alkylamino, dialkylamino, C 1-3  alkyl and halo; \n m is selected from 5, 6, 7, 8, 9, 10, 11, 12, and 13; and \n n is selected from 1, 2, 3, 4, and 5.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.54348
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15846084', '16005286', '15476253', '15493281', '15498698']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9390164894263784
- 35 USC 102 Novelty (BERT): 0.742543347108263
- Combined Prediction Score: 0.919369175194567
- Mean Citation Score: 893.7342580000003
- Max Citation Score: 912.8712
- Similarity Product: 768.9467227326393

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test