PATENT CLAIM ANALYSIS

Application Number: 16039123
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["435", "069600"]

Abstract:
The present invention relates to methods of upregulating the high mannose glycoform content of a recombinant protein during a mammalian cell culture by manipulating the mannose to total hexose ratio in the cell culture media formulation.

Claim (Index 30):
The method of  claim 29 , wherein the concentration of L-asparagine of the cell culture media is monitored during L-asparagine starvation.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 95.0
- Lexical Diversity: 1.27586
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14289943', '15285392', '14776404', '15115615', '15111470']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6930916943465685
- 35 USC 102 Novelty (BERT): 0.6224173880786777
- Combined Prediction Score: 0.6860242637197794
- Mean Citation Score: 474.1191400000001
- Max Citation Score: 641.5584
- Similarity Product: 507.743552838707

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test