PATENT CLAIM ANALYSIS

Application Number: 16374701
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-07
Patent Classification: ["514", "001100"]

Abstract:
By employing a pharmacodynamic dosing regimen, the effectiveness of a protocol for treatment of a proteinuric kidney disease with voclosporin can be maximized while minimizing undesirable side effects.

Claim (Index 17):
A pharmacodynamic method to treat a proteinuric kidney disease which method comprises administering to a subject diagnosed with a proteinuric kidney disease predetermined daily dosages of effective amounts of voclosporin over a projected treatment period to an end point, said pharmacodynamic method further comprising:\n (a) measuring urinary protein creatinine ratio (UPCR) of said subject at a first time point prior to said treatment period and a second time point occurring prior to the end point but after the start of the treatment period and determining any reduction of said UPCR between said first and second time points, and (b) if the UPCR of said subject fails to show a reduction of at least a predetermined amount at said second time point, discontinuing administering voclosporin to the subject and continuing said administering if said predetermined amount of reduction is shown.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 100.0
- Lexical Diversity: 1.11111
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15835219', '13737535', '16208172', '16335662', '15918401']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7079973980654759
- 35 USC 102 Novelty (BERT): 0.5711266753828865
- Combined Prediction Score: 0.6943103257972171
- Mean Citation Score: 235.234764
- Max Citation Score: 494.36295
- Similarity Product: 360.4837494068384

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test