PATENT CLAIM ANALYSIS

Application Number: 15977948
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["548", "537000"]

Abstract:
A method is provided to conveniently separate racemic (3R,4S)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide and (3S,4R)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide using selective crystallization with chiral carboxylic acids.

Claim (Index 1):
An amine compound represented by formula I: wherein: X is O, S, or NR e ; R a  is H, lower alkyl, or lower cycloalkyl; R b  is \u2014CH 2 CH\u2550CH 2 , \u2014CH 2 CH 2 CH 2 Z 1 , \u2014(CH 2 ) n C(O)H, or \u2014(CH 2 ) n CO 2 Z 2 ; R c  and R d  are independently H, lower alkyl, lower cycloalkyl, silyl, acyl, acyloxy; or R c  and R d , together with the N that links them, form an optionally substituted 3- to 6-membered heteroaryl or heterocyclic ring; R e  is H or lower alkyl; n is 1 or 2; Z 1  is halogen, alkyl sulfonate, aryl sulfonate, or an alkyl sulfonate optionally substituted with one or more halogen; and Z 2  is H, lower alkyl, or lower cycloalkyl; wherein the amine compound has an enantiomeric excess of greater than 75% ee.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 93.0
- Lexical Diversity: 1.375
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13276806', '14614115', '12748745', '15111449', '15207902']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7148608278826173
- 35 USC 102 Novelty (BERT): 0.5019750749335564
- Combined Prediction Score: 0.6935722525877112
- Mean Citation Score: 232.729944
- Max Citation Score: 242.55133
- Similarity Product: 182.11847148118613

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test