PATENT CLAIM ANALYSIS

Application Number: 15923951
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["800", "015000"]

Abstract:
Materials and methods for making multiplex gene edits in cells and are presented. Further methods include animals and methods of making the same. Methods of making chimeric animals are presented, as well as chimeric animals.

Claim (Index 28):
The method of  claim 25 , further comprising simultaneously introducing into the cell one or more of:\n a third targeted endonuclease directed to a third chromosomal DNA site and a third HDR template that has homology to the third target chromosomal DNA site wherein the third HDR template replaces the third target chromosomal DNA site; a fourth targeted endonuclease directed to a fourth chromosomal DNA site and a fourth HDR template that has homology to the fourth target chromosomal DNA site wherein the fourth HDR template replaces the fourth target chromosomal DNA site; a fifth targeted endonuclease directed to a fifth chromosomal DNA site and a fifth HDR template that has homology to the fifth target chromosomal DNA site wherein the fifth HDR template replaces the fifth target chromosomal DNA site; a sixth targeted endonuclease directed to a sixth chromosomal DNA site and a sixth HDR template that has homology to the sixth target chromosomal DNA site wherein the sixth HDR template replaces the sixth target chromosomal DNA site; and a seventh targeted endonuclease directed to a seventh chromosomal DNA site and a seventh HDR template that has homology to the seventh target chromosomal DNA site wherein the seventh HDR template replaces the seventh target chromosomal DNA site.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 90.0
- Lexical Diversity: 1.625
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14263446', '14991818', '14013250', '15354270', '14515503']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5760654838813053
- 35 USC 102 Novelty (BERT): 0.5187519167023609
- Combined Prediction Score: 0.5703341271634109
- Mean Citation Score: 247.29948800000005
- Max Citation Score: 345.777
- Similarity Product: 212.31720521771908

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test