PATENT CLAIM ANALYSIS

Application Number: 16038739
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["514", "093000"]

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Claim (Index 32):
A method of treating a disease, disorder, or condition in a mammal comprising administering a therapeutically effective amount of a compound, or a stereoisomer or pharmaceutically acceptable salt thereof, to the mammal in need thereof; wherein activation of at least one lysophosphatidic acid (LPA) receptors by LPA contributes to the symptomology or progression of the disease, disorder or condition, and the compound is represented by Formula (III): R 2  is independently selected from CH 3  and CD 3 ; R 13  is independently selected from H and C 1-4  alkyl; R 3  is independently selected from H and C 1-4  alkyl; R 4  is independently selected from C 1-6  alkyl substituted with 1-3 R 9 , \u2014(CR 7 R 7 ) r \u2014C 3-6  cycloalkyl substituted with 1-3 R 8 , and \u2014(CR 7 R 7 ) r -aryl substituted with 1-3 R 8 ; R 5  is independently selected from H, F, Cl, CN and C 1-4  alkyl; provided one of R 5  is H; R 6  is R 7  is independently selected from H, C 1-4  alkyl, and C 3-6  cycloalkyl; or R 7  and R 7 , together with the carbon atom to which they both attach, form a C 3-6  cycloalkyl ring; R 8  is independently selected from H, C 1-6  alkyl substituted with 1-5 R 9 , C 3-6  cycloalkyl, F, Cl, Br, CN, \u2550O, and COOH; R 9  is independently selected from H, F, Cl, NH 2 , OH, OC 1-5 alkyl, C 1-5 alkyl, C 3-6  cycloalkyl, and phenyl, wherein when R 9  is Cl, NH 2  or OH, it is not substituted on C 1  of the alkyl to which it is attached; R 10  is independently selected from H, D, C 1-4  alkyl, and F; R 11  is independently selected from CN, \u2014C(\u2550O)R 12 , and tetrazolyl; R 12  is independently selected from OH, OC 1-4  alkyl, NH 2 , and NHSO 2 C 1-4  alky; and r is independently selected from zero, 1, 2, 3, and 4.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 95.0
- Lexical Diversity: 1.2
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15628104', '15323967', '15534105', '14352554', '14488294']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7042080408253942
- 35 USC 102 Novelty (BERT): 0.5624533830504166
- Combined Prediction Score: 0.6900325750478965
- Mean Citation Score: 310.378278
- Max Citation Score: 437.55276
- Similarity Product: 333.8202649870633

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test