PATENT CLAIM ANALYSIS

Application Number: 16364813
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-08
Patent Classification: ["424", "130100"]

Abstract:
The present invention relates to a method for screening an inhibitor of ATP11C or CDC50A, comprising determining (a) exposure of phosphatidylserine on cell surface, (b) engulfment of cells by macrophages, or (c) cleavage of ATP11C by caspase. The present invention also relates to a method for inducing engulfment of cells by macrophages, comprising inhibiting ATP11C or CDC50A.

Claim (Index 12):
The method according to  claim 11 , comprising the steps of:\n (1) treating cells expressing ATP11C and CDC50A with a candidate for said inhibitor, and (2) determining exposure of phosphatidylserine on cell surface of the cells, wherein the candidate is selected as an inhibitor of ATP11C or CDC50A when the exposure of phosphatidylserine on cell surface is increased by the treatment with said candidate compared to a control.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 99.0
- Lexical Diversity: 1.86486
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15301762', '14440968', '14394320', '12308542', '15359140']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6731715473297852
- 35 USC 102 Novelty (BERT): 0.63787077611048
- Combined Prediction Score: 0.6696414702078547
- Mean Citation Score: 271.185914
- Max Citation Score: 649.8838
- Similarity Product: 547.1153182376146

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test