PATENT CLAIM ANALYSIS

Application Number: 16119962
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["544", "387000"]

Abstract:
The present invention relates to compounds and compositions for inhibition of FASN, their synthesis, applications, and antidotes.

Claim (Index 28):
A fatty acid synthase inhibitor compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R 1  is a 3 or 4 membered cycloalkyl or heterocycloalkyl wherein (i) the heteroatom ring member of the 3 or 4 membered heterocycloalkyl is independently selected from O, S, or N, and (ii) each of said 3 or 4 membered cycloalkyl or heterocycloalkyl is either unsubstituted or optionally substituted with substituents selected from the group consisting of \u2014R a , \u2014OR a , \u2014NHR a , and \u2014NR a R a1 ; L is a 6-membered monocyclic substituted heteroalkyl wherein the heteroatom ring members consist of one or two N and L is substituted with one or more R b ; A and B are independently O; Ar 1  is a 6-membered monocyclic aryl either unsubstituted or optionally independently substituted with 1 or more substituents which can be the same or different and are independently selected from the group consisting of halo, alkyl, \u2014CH z F 3-z , cyano, hydroxyl, hydroxylalkyl, amino, aminoalkyl-, (amino)alkoxy-, \u2014CONH 2 , \u2014C(O)NH(alkyl), \u2014C(O)N(alkyl) 2 , \u2014C(O)NH(aryl), \u2014C(O)N(aryl) 2 , \u2014OCH z F 3-z , -alkyl, -alkenyl, -alkynyl, -alkoxy (alkoxyalkyl)amino-, \u2014N(R)\u2014C(O)-alkyl, \u2014N(R c )\u2014C(O)-aryl, -cycloalkyl, -heterocycloalkyl, -aryl, and -heteroaryl, with the proviso that no two adjacent ring heteroatoms are both S or both O; R 2  is a substituted or unsubstituted 9 membered 6,5 bicyclic heteroaryl and said heteroaryl has 1, 2, 3, or 4 heteroatoms and said heteroatoms are independently O, S, or N; R a  and R a1  are independently H, halo, C 1 -C 4  alkyl, or C 3 -C 4  cycloalkyl; R b  is methyl; and z is 0, 1 or 2.

Metadata:
- Claim Count in Document: 147.0
- Percentile: 96.0
- Lexical Diversity: 1.16667
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15786539', '15905524', '14451600', '14774937', '14631625']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8381933396690286
- 35 USC 102 Novelty (BERT): 0.5903548153619318
- Combined Prediction Score: 0.813409487238319
- Mean Citation Score: 397.345142
- Max Citation Score: 544.4386599999998
- Similarity Product: 448.45727786322817

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test