PATENT CLAIM ANALYSIS

Application Number: 15780971
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-09
Patent Classification: ["514", "017800"]

Abstract:
The present invention provides methods for treating a subject afflicted with a protein accumulation disease or TBI, comprising administering to the subject at least one compound that increases the level of active cathepsin B in cells of the subject, or a pharmaceutically acceptable salt or ester thereof, in an amount that is effective to treat the subject. The present invention also provides compositions for treating a subject afflicted with a protein accumulation disease or TBI.

Claim (Index 49):
The pharmaceutical composition of  claim 48 , wherein the pharmaceutical composition is in unit dosage form, useful in treating a subject afflicted with a protein accumulation disease or TBI, which comprises:\n a. an amount of a first compound; b. an amount of a second compound, wherein the respective amounts of the first compound and the second compound in the composition are effective, upon concomitant administration to the subject of one or more of the unit dosage forms of the composition, to treat the subject, and wherein the first compound is PADK or a PADK analogue, or a pharmaceutically acceptable salt or ester thereof, and wherein the second compound is a flavonoid or a phenylalanyl proline compound, or a pharmaceutically acceptable salt or ester thereof.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 94.0
- Lexical Diversity: 1.70213
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13380775', '11780350', '09961381', '14486679', '15035909']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7578453184609423
- 35 USC 102 Novelty (BERT): 0.5052870618060997
- Combined Prediction Score: 0.732589492795458
- Mean Citation Score: 237.83650000000003
- Max Citation Score: 245.61986
- Similarity Product: 166.54195594876168

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test