PATENT CLAIM ANALYSIS

Application Number: 16166917
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-02
Patent Classification: ["536", "023100"]

Abstract:
Described are post transcriptionally chemically modified double strand RNAs (MdsRNAs) having more than 30 base pairs. The MdsRNAs inhibit gene expression in target organisms. Also described are methods of making and using MdsRNAs.

Claim (Index 12):
The composition of  claim 11 , wherein R 1  is alkyl; substituted alkyl; alkenyl; substituted alkenyl; alkynyl; substituted alkynyl; aryl; substituted aryl; C1-C10 alkyl, C1-C10 alkenyl, or C1-C10 alkynyl wherein alkyl and alkenyl can be linear, branched or cyclic; hydrogen if n=1; methyl; ethyl; propyl; isopropyl; butyl; isobutyl; tert-butyl; pentyl; hexyl; cyclohexyl; heptyl; octyl; nonyl; decyl; vinyl; allyl; ethynyl; benzyl; cinnamyl; C6-C14 aryl; C6-C14 substituted aryl; heterocyclyl; C5-C14 heterocyclyl; phenyl; mono or disubstituted phenyl wherein the substituents are selected from C1-C10 alkyl, C1-C10 alkenyl, C1-C6 alkoxy, halogen, nitro, methylsulfonyl, and trifluoromethyl; 2-nitrophenyl; 4-nitrophenyl; 2,4-dinitrophenyl; 2-trifluromethylphenyl; 4-triflouromethylphenyl; styryl; C8-C16 substituted styryl; 2-aminophenyl; mono or disubstituted 2-aminophenyl wherein the substituents are selected from C1-C10 alkyl, C1-C10 alkenyl, C1-C6 alkoxy, halogen, nitro, methylsulfonyl, and trifluoromethyl; N-alkyl-2-aminophenyl or N-aryl-2-aminophenyl wherein alkyl has the formula \u2014C m H 2m+1  (wherein m is an integer less than or equal to 12) and aryl is an aromatic moiety; 2-amino-3-methyl-phenyl; 2-amino-5-chlorophenyl; 2-methyl-5-chlorophenyl; N-methyla-2-minophenyl; N-ethyl-2-aminophenyl; N-propyl-2-aminophenyl; N-butyl2-aminophenyl; N-pentyl-2-aminophenyl; N-methyl-2-amino-4-nitrophenyl; 2-methyl-3-furyl; 2-methylnicotyl or N-trifluoromethyl-2-aminophenyl; silanyl; substituted silanyl; C1-C10 alkylsilanyl; C3-C12 trialkylsilanyl; C2-C12 alkoxyalkyl; C2-C12 alkoxyalkenyl; C2-C12 alkylthioalkyl; alkylsulfonyl; C1-C10 alkylsulfonyl; C1-C10 haloalkyl; C1-C10 haloalkenyl or C1-C10 aminoalkyl; \u2014(CH 2 CH 2 O) p CH 3 , \u2014(CH 2 CH 2 O) p H, or \u2014(CH 2 CH 2 O) p COOR 4  wherein p is an integer from 2 to 8 and R 4  is H, alkyl, substituted alkyl, aryl, or substituted aryl; \u2014(CH 2 CH 2 O) 8 COOH; \u2014CH 2 CH 2 OH; \u2014(CH 2 CH 2 O) 4 OH; \u2014(CH 2 CH 2 O) 6 OH; \u2014(CH 2 CH 2 O) 8 OH; \u2014(CH 2 CH 2 O) 8 COOMe; \u2014(CH 2 CH 2 O) 4 OMe; \u2014(CH 2 CH 2 O) 6 OMe; \u2014(CH 2 CH 2 O) 8 OMe; \u2014CH 2 OCH 3 ; \u2014CH 2 OCH 2 CH 3 ; or \u2014CH 2 OCH 2 CH 2 OCH 3 .

Metadata:
- Claim Count in Document: 20.0
- Percentile: 97.0
- Lexical Diversity: 1.15152
- Patent Class: 536.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15803948', '14769361', '10701285', '12724267', '12445868']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.614075788882743
- 35 USC 102 Novelty (BERT): 0.6022165069354415
- Combined Prediction Score: 0.6128898606880128
- Mean Citation Score: 283.232702
- Max Citation Score: 582.22955
- Similarity Product: 458.55582707673307

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test