PATENT CLAIM ANALYSIS

Application Number: 15765799
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "264100"]

Abstract:
The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.

Claim (Index 14):
A kit for measuring PI3K activity and MEK activity, the kit comprising\n 1) a first reagent for cytolysis, comprising a surface active agent, a protease inhibitor, and a phosphatase inhibitor, 2A) a second reagent for measuring MEK, comprising an anti-MEK antibody, 2B) a second reagent for measuring PI3K, comprising an anti-PI3K antibody, 3A) a third reagent for measuring MEK, comprising a substrate for MEK and ATP, 3B) a third reagent for measuring PI3K, comprising a substrate for PI3K and ATP, 4) a fourth reagent comprising D-Glucose; ADP-Hexokinase; Glucose-6-phosphate dehydrogenase; Diphorase and NADP, 5) a fifth reagent comprising Luminol and Peroxidase, and 6) a washing sixth reagent comprising a surface active agent.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.47727
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14194323', '12854144', '15516780', '14895286', '14690001']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7393132432217134
- 35 USC 102 Novelty (BERT): 0.5262861225293648
- Combined Prediction Score: 0.7180105311524786
- Mean Citation Score: 288.389476
- Max Citation Score: 317.6930200000001
- Similarity Product: 224.19120501152284

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test