PATENT CLAIM ANALYSIS

Application Number: 16195794
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["546", "348000"]

Abstract:
The present invention comprises compounds of Formula I and their use in the inhibition of cell proliferation in therapeutic treatments. Pharmaceutical compositions comprising at least one compound of Formula I and at least one pharmaceutical excipient are disclosed, as well as methods of using compounds of Formula I and pharmaceutical compositions thereof for treatment of hyper-proliferative diseases and other disorders.

Claim (Index 1):
A compound of Formula I: all salts, prodrugs, and tautomers, and isomers thereof, wherein:\n A is \u2014SO 2 NR 1 R 2  or \u2014C(O)NHOH; \n X and X\u2032 are independently hydrogen, deuterium, halo, C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, aryl, heterocyclyl, \u2014OR 3 , \u2014CN, \u2014C(O)OR 3 , \u2014OC(O)R 3 , \u2014NR 3 R 4 , \u2014NHC(O)R 3 , \u2014NHSO 2 R 3 , \u2014C(O)NHR 3 , \u2014SR 3 , \u2014SO 2 R 3  or \u2014SO 2 NR 3 R 4 ; or X and X\u2032, taken together with the aryl C atoms to which they are attached, form a carbocyclic or heterocyclic ring; \n Y is halo, C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, aryl or heterocyclyl; \n Z is C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, \u2014C(O)OR 3  or \u2014C(O)NR 3 R 4 ; \n Q and Q\u2032 are independently hydrogen, deuterium, halo, C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, \u2014OR 3 , \u2014CN, \u2014C(O)OR 3 , \u2014OC(O)R 3 , \u2014NR 3 R 4 , \u2014NHC(O)R 3 , \u2014NHSO 2 R 3 , \u2014C(O)NHR 3 , \u2014SR 3 , \u2014SO 2 R 3  or \u2014SO 2 NR 3 R 4 ; \n Q\u2033 is hydrogen, deuterium, halo, C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, \u2014OR 3 , \u2014CN, \u2014C(O)OR 3 , \u2014OC(O)R 3 , \u2014NR 3 R 4 , \u2014NHC(O)R 3 , \u2014NHSO 2 R 3 , \u2014C(O)NHR 3 , \u2014SR 3 , \u2014SO 2 R 3  or \u2014SO 2 NR 3 R 4 ; \n R l  and R 2  are independently hydrogen, deuterium, C 1 -C 6  alkyl, C 3 -C 7  cycloalkyl, \u2014C(O)(C 1 -C 6  alkyl) or \u2014C(O)(C 3 -C 7  cycloalkyl); or R 1  and R 2 , taken together with the N atom to which they are attached, form a heterocyclic ring; and \n R 3  and R 4  are independently hydrogen, deuterium, C 1 -C 6  alkyl or C 3 -C 7  cycloalkyl; or R 3  and R 4 , taken together with the N atom to which they are attached, form a heterocyclic ring.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 98.0
- Lexical Diversity: 1.5
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14772616', '15574800', '14654226', '12997066', '11244628']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7696036378247342
- 35 USC 102 Novelty (BERT): 0.5084725248768246
- Combined Prediction Score: 0.7434905265299432
- Mean Citation Score: 252.14883
- Max Citation Score: 314.61008
- Similarity Product: 290.13299206579205

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test