PATENT CLAIM ANALYSIS

Application Number: 16042108
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["436", "518000"]

Abstract:
Materials, systems and methods are provided for qualitative assessment of exposure of a person to ionizing radiation by measuring amounts of the biomarkers, wherein a change compared with corresponding un-irradiated control reference ranges of the biomarkers, provides the assessment, wherein the biomarkers include (i) alpha-1-Antichymotrypsin (ACT), (ii) Fms-related tyrosine kinase 3 ligand (Flt3L), and (iii) one or more additional proteins.

Claim (Index 15):
A method for qualitative assessment of exposure of a person to ionizing radiation, comprising the steps of:\n (a) separating biomarkers of a blood sample of the person; and (a) measuring amounts of the separated biomarkers, wherein a change in the amounts, compared with corresponding un-irradiated control reference ranges of the biomarkers, provides the assessment, wherein the biomarkers comprise (i) alpha-l-Antichymotrypsin (ACT), (ii) Fms-related tyrosine kinase 3 ligand (Flt3L), and (iii) one or more additional proteins selected from the group consisting of: Serum amyloid A isoform 1 or 2 (SAA1 or SAA2), C-reactive protein (CRP), Salivary alpha amylase (AMY1A), Alpha-1-antitrypsin isoform 4 (SERPINA1), Neutrophil gelatinase-associated lipocalin (NGAL), Alpha-1-acid glycoprotein 1 or 2, Leucine-rich alpha-2-glycoprotein (LRG1), Tenascin-C (TNC), Clusterin (CLU), Hemopexin (HPX), Haptoglobin (HP), Apolipoprotein A-IV (APOA4), Interleukin 15 (IL15), Interleukin 18 (IL18), and Monocyte chemotactic protein 1 (MCP1).

Metadata:
- Claim Count in Document: 50.0
- Percentile: 95.0
- Lexical Diversity: 1.48077
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15026577', '12304566', '14854514', '14435991', '15873840']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6013139247041569
- 35 USC 102 Novelty (BERT): 0.4840674984348884
- Combined Prediction Score: 0.58958928207723
- Mean Citation Score: 176.140622
- Max Citation Score: 221.23999
- Similarity Product: 164.87116106115695

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test