PATENT CLAIM ANALYSIS

Application Number: 15921560
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["514", "349000"]

Abstract:
The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.

Claim (Index 1):
A pharmaceutical composition in unit dose comprising:\n i) a compound of formula II: wherein m is an integer selected from 1 to 4; W is selected from H and halogens; the halogen is selected from F, Cl\u2014, Br\u2014 or I\u2014; R1, R2, R3, R4 are each independently selected from the group consisting in H, phenyl, 2-, 3- or 4-substituted phenyl, 2- or 3-naphthyl, pyrrolyl, furanyl, thiofuranyl, pyrimidinyl, imidazolyl, benzyl, isoPropyl, tertButyl, (CH 2 ) n CH 3 , alkenyl, alkynyl; the subscript n is an integer independently selected from 0 to 15; X is O, S, CR5R6, NR7, NHCOR8, or NHSO 2 R9; where R5, R6, R7, R8, R9 are each independently selected from the group consisting in H, phenyl, 2-, 3- or 4-substituted phenyl, 2- or 3-naphthyl, pyrrolyl, furanyl, thiofuranyl, pyrimidinyl, imidazolyl, benzyl, isoPropyl, tertButyl, or (CH 2 ) n CH 3 , the subscript n is an integer independently selected from 1 to 15; Y is N; Z is H, NO 2 , OH, NR10R11 where R10 and R11 are each independently selected from the group consisting in H and (CH 2 ) n CH 3 , NHCOR12 where R12 is selected from the group consisting of (CH 2 ) n CH, aromatic and heteroaromatics such as phenyl, naphthyl, pyrrolyl, furanyl, thiofuranyl, pyrimidinyl, imidazolyl, COOR13 where R13 is selected from the group consisting of H, (CH 2 ) n CH, aromatic and heteroaromatics such as phenyl, naphthyl, pyrrolyl, furanyl, thiofuranyl, pyrimidinyl, imidazolyl, NHSO 2 R14 where R14 is selected from the group consisting of phenyl, 2-, 3- or 4, substituted phenyl, naphthyl, heteroaromatics such as pyrrolyl, furanyl, thiofuranyl, pyrimidinyl, imidazolyl, benzyl, (CH 2 ) n CH 3 ; the subscript n is an integer independently selected from 1 to 15, wherein the compound in the unit dose is in an amount that ranges between 0.1 mg and 1000 mg; and ii) a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 90.0
- Lexical Diversity: 1.16129
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14366917', '15017986', '15560743', '12989131', '15480689']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7802566593603295
- 35 USC 102 Novelty (BERT): 0.627727534854658
- Combined Prediction Score: 0.7650037469097625
- Mean Citation Score: 413.240096
- Max Citation Score: 703.2187
- Similarity Product: 506.9498153301119

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test