PATENT CLAIM ANALYSIS

Application Number: 15920222
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["435", "006110"]

Abstract:
The present disclosure provides methods for detecting a single-stranded target RNA. The present disclosure provides methods of cleaving a precursor C2c2 guide RNA array into two or more C2c2 guide RNAs. The present disclosure provides a kit for detecting a target RNA in a sample.

Claim (Index 108):
A kit comprising:\n (a) a first labeled detector RNA that lacks U and comprises at least one A; (b) a second labeled detector RNA that lacks A and comprises at least one U; (c) a first C2c2 protein, or a nucleic acid encoding the first C2c2 protein, wherein the first C2c2 protein can cleave adenine+ RNAs when activated but cannot cleave RNAs that lack A, and wherein the first C2c2 protein can cleave the first labeled detector RNA but not the second labeled detector RNA; and (d) a second C2c2 protein, or a nucleic acid encoding the second C2c2 protein, wherein the second C2c2 protein can cleave uracil+ RNAs when activated but cannot cleave RNAs that lack U, and wherein the second C2c2 protein can cleave the second labeled detector RNA but not the first labeled detector RNA.

Metadata:
- Claim Count in Document: 110.0
- Percentile: 90.0
- Lexical Diversity: 1.84615
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15467922', '15917546', '15917549', '15916271', '15897089']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6483450533457936
- 35 USC 102 Novelty (BERT): 0.6358645395126888
- Combined Prediction Score: 0.6470970019624831
- Mean Citation Score: 445.34534400000007
- Max Citation Score: 668.0506
- Similarity Product: 549.334077583766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test