PATENT CLAIM ANALYSIS

Application Number: 15954291
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-10
Patent Classification: ["435", "377000"]

Abstract:
Methods are disclosed for reprogramming a somatic cell, including an adherent cell and a cell in suspension, into an induced pluripotent stem comprising expressing exogenous Sox-2, exogenous Klf-4, exogenous Oct3/4 from DNA that has not integrated into the genome of the somatic cell, suppressing p53 activity within the somatic cell, and exposing the somatic cell to reprogramming-assistance factors comprising an exogenous Alk-5 inhibitor, an exogenous histone deacetylase inhibitor, and an exogenous activator of glycolysis. Compositions and kits for use in such methods are also disclosed as are cells made by such a method.

Claim (Index 14):
The method according to  claim 12 , wherein the iPS cell is differentiated into an endodermal, mesodermal, or ectodermal cell.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.71667
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12939454', '13197529', '14438106', '13997014', '13389359']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6859287452059819
- 35 USC 102 Novelty (BERT): 0.5558023351332675
- Combined Prediction Score: 0.6729161041987105
- Mean Citation Score: 477.53489
- Max Citation Score: 523.6735
- Similarity Product: 295.738000130266

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test