PATENT CLAIM ANALYSIS

Application Number: 15759788
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["514", "003800"]

Abstract:
Provided herein are compositions and methods relating to cell-penetrating conjugates for the delivery of therapeutic polypeptides or polynucleotides to cells or tissues of the body. The delivery conjugate comprises a cell-penetrating peptide and a nuclear localization signal sequence plus an effector moiety (such as a polypeptide or polynucleotide) as the payload, optionally further including an epitope tag as well as a solubility peptide and a configurating peptide. The delivery conjugate can also include a component capable of specifically directing the conjugate to a target cell or tissue, making the conjugate effective for treating diseases in the target tissue.

Claim (Index 22):
The polynucleotide sequence of  claim 19 , wherein the cell penetrating peptide is selected from a group consisting of a HIV TAT protein or a fragment thereof comprising the protein transduction domain,  Drosophila  Antennapedia (Antp) peptide and polyarginine (Arg8) peptide.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 90.0
- Lexical Diversity: 1.59091
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13082528', '13885956', '13082526', '11286920', '10972222']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7530636577153215
- 35 USC 102 Novelty (BERT): 0.5042803960752938
- Combined Prediction Score: 0.7281853315513187
- Mean Citation Score: 243.619144
- Max Citation Score: 253.6771
- Similarity Product: 173.3251079202175

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test