PATENT CLAIM ANALYSIS

Application Number: 16215183
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-03
Patent Classification: ["514", "021300"]

Abstract:
The present invention is directed to an amphipathic peptide and methods of using the amphipathic peptide for delivering small molecule agents to a cell. Ideally, the amphipathic cell penetrating peptide comprises less than approximately 50 amino acid residues with at least 6 arginine residues, at least 12 Alanine Residues, at least 6 leucine residues, optionally at least one cysteine residue, and at least two but no greater than three glutamic acids wherein the arginine residues are evenly distributed along the length of the peptide; and the peptide has a defined ratio of arginine to negatively charged amino acid residues and a defined ratio of hydrophilic amino acid residues to hydrophobic amino acid residues. The present invention is also directed to a nanoparticle and cell delivery system comprising the amphipathic cell penetrating peptide of the invention. The peptide, nanoparticle or cell delivery system of the invention may be used in therapy. For example, the peptide may be used as a therapeutic agent delivery system, in which the therapeutic agent may include nucleic acids or other small molecules.

Claim (Index 15):
The cell delivery system according to  claim 10  wherein the other agent is a small molecule agent.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 98.0
- Lexical Diversity: 2.15909
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14649606', '15688484', '14009648', '15160939', '12714106']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7793786263975231
- 35 USC 102 Novelty (BERT): 0.6847459339213242
- Combined Prediction Score: 0.7699153571499032
- Mean Citation Score: 456.45749000000006
- Max Citation Score: 693.7242
- Similarity Product: 664.5116213792681

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test