PATENT CLAIM ANALYSIS

Application Number: 15934176
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "378000"]

Abstract:
A compound of Formula (I)) or or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating hearing loss or balance disorder: wherein R 1  through R 3 , and L are as defined herein.

Claim (Index 11):
The compound or a pharmaceutically acceptable salt thereof according to  claim 1  selected from:\n Example 8: N-(5-(4-methylpiperazin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 19: N-(5-(3-(methylsulfonamido)azetidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 27: N-(5-(3-carbamoylazetidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 45: (S)\u2014N-(5-(3-fluoropyrrolidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 51: N-(5-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 52: N-(5-(5-methyl-2,5-diazabicyclo[2.2.2]octan-2-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 54: N-(5-(4-(2-hydroxyethyl)piperazin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 61: N-(5-(3-(methylcarbamoyl)azetidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 65: N-(5-(3-carbamoylazetidin-1-yl)pentyl)-5-(4-fluorophenyl)isoxazole-3-carboxamide; \n Example 72: N-(5-(3-sulfamoylazetidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 73: 5-(5-fluorothiophen-2-yl)-N-(5-(4-methylpiperazin-1-yl)pentyl)isoxazole-3-carboxamide; \n Example 74: N-(3,3-difluoro-5-(4-methylpiperazin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 77: N-(5-(3-((cyanomethyl)carbamoyl)azetidin-1-yl)pentyl)-5-(thiophen-2-yl)isoxazole-3-carboxamide; \n Example 83: N-(5-(3-((2-hydroxycyclopentyl)carbamoyl)azetidin-1-yl)pentyl)-5-(thiophen-2-yl) isoxazole-3-carboxamide; \n Example 85: 5-(4-fluorophenyl)-N-(5-(3-(methylcarbamoyl)azetidin-1-yl)pentyl)isoxazole-3-carboxamide; and \n Example 88: N-(5-(3-((Cyanomethyl)carbamoyl)azetidin-1-yl)pentyl)-5-(4-fluorophenyl)isoxazole-3-carboxamide.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.11905
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14381187', '13993198', '14977508', '13360050', '15124264']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.76725418373767
- 35 USC 102 Novelty (BERT): 0.5108472980115413
- Combined Prediction Score: 0.741613495165057
- Mean Citation Score: 282.68990799999995
- Max Citation Score: 290.67834
- Similarity Product: 223.0809461637997

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test