PATENT CLAIM ANALYSIS

Application Number: 16006374
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "064000"]

Abstract:
The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: R 1  is H or CH 3  R 2  is not H, and is CH 3 , or C1-C6 straight chain, or branched alkyl, or C3-C6 cycloalkyl group, or unsaturated alkenyl, including C═CH 2 ; R 3  is H, CH 3 , or a C1-C6 alkyl or cycloalkyl group, a heteroatom-substituted alkyl; and R 4  is a C1 to C6 alkyl, or substituted alkyl group, especially including substituents which possess positive charge, or a hydroxyl group; or R 4  is an SR a , where R a  is an unsubstituted C1 to C6 alkyl group, a substituted C1 to C6 alkyl group, or a functional group that is positively charged, or which bears a positive charge when in aqueous solution at pH 7; or R 4  is a CH 2 OR b , where R b =C1 to C6 alkyl or substituted alkyl groups, substituted or unsubstituted aryl, or a heteroaryl groups.

Claim (Index 26):
The antibiotic of  claim 16 , wherein M is selected from an alkoxyalkyl, alkylcarbonyloxyalkyl, alkoxycarbonyloxyalkyl, cycloalkoxyalkyl, alkenyloxyalkyl, aryloxyalkyl, alkoxyaryl, alkylthioalkyl, cycloalkylthioalkyl, alkenylthioalkyl, arylthioalkyl or alkylthioaryl group, or the groups can be substituted in the alkyl or aryl portions thereof with acyl or halo groups, or acetoxymethyl, 1-acetoxyethyl, 1-acetoxypropyl, pivaloyloxymethyl, 1-isopropyloxycarbonyloxyethyl, 1-cyclohexyloxycarbonyloxyethyl, phthalidyl, or (2-oxo-5-methyl-1,3-dioxolen-4-yl)methyl.

Metadata:
- Claim Count in Document: 77.0
- Percentile: 94.0
- Lexical Diversity: 2.55263
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10572742', '14766826', '10311282', '12195706', '13550366']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.764577008777258
- 35 USC 102 Novelty (BERT): 0.5269492120879706
- Combined Prediction Score: 0.7408142291083293
- Mean Citation Score: 279.07053800000006
- Max Citation Score: 295.82526
- Similarity Product: 186.20049875735523

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test