PATENT CLAIM ANALYSIS

Application Number: 16008974
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["800", "018000"]

Abstract:
This document relates to methods and materials involved in the removal of senescent cells within a mammal. For example, transgenic non-human animals that can be induced to delete senescent cells are provided.

Claim (Index 1):
A nucleic acid construct comprising a p16 Ink4a  promoter sequence operably linked to a nucleic acid sequence encoding a polypeptide such that the polypeptide is selectively expressed when the construct is present in senescent cells,\n wherein expression of the polypeptide directly induces cell death in senescent cells but in less than 10% of non-senescent cells, thereby delaying presentation or progression of an age-related phenotype in or around a location where the senescent cells are present in vivo.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 94.0
- Lexical Diversity: 1.12903
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14792208', '15943356', '15870172', '15067543', '15080991']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5900026193156607
- 35 USC 102 Novelty (BERT): 0.5603889668743474
- Combined Prediction Score: 0.5870412540715294
- Mean Citation Score: 379.506456
- Max Citation Score: 479.47028
- Similarity Product: 385.0228812682652

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test