PATENT CLAIM ANALYSIS

Application Number: 16039196
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "254060"]

Abstract:
Disclosed herein are pharmaceutical compositions and dosage forms including N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino) benzamide that are useful in the treatment of subjects having cancer. The present disclosure also provides methods for preparing these pharmaceutical compositions and dosage forms, and methods of treating subjects having cancer utilizing the pharmaceutical compositions and dosage forms provided herein.

Claim (Index 15):
A pharmaceutical composition comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide and at least one pharmaceutically acceptable excipient, wherein said pharmaceutical composition is in the form of a tablet or capsule, and wherein said tablet or capsule has a dissolution profile wherein at least about 30% of said N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide has been released from said tablet or capsule at about 60 minutes when tested in USP Apparatus Type I Basket Method at 50 rpm in 500 mL of sodium acetate buffer at a pH of 4.5 and at about 37\u00b0 C.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 95.0
- Lexical Diversity: 1.53333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14623904', '14953969', '12520387', '15172478', '14528475']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7633086671827661
- 35 USC 102 Novelty (BERT): 0.5705006155623885
- Combined Prediction Score: 0.7440278620207283
- Mean Citation Score: 427.776604
- Max Citation Score: 470.46823
- Similarity Product: 355.84671286458075

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test