PATENT CLAIM ANALYSIS

Application Number: 16150070
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "210200"]

Abstract:
The invention provides compounds having the general Formula (I); and pharmaceutically acceptable salts thereof; wherein the variables R A , R AA , subscript n, subscript q, ring A, X 2 , L, subscript m, X 1 , R 1 , R 2 , R 3 , R 4 , R 5 , D and E have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Claim (Index 16):
The compound or pharmaceutically acceptable salt of  claim 1 , wherein:\n R o  is hydrogen or C 1-6  alkyl; R 1  and R 2  are each independently selected from the group consisting of hydrogen and C 1-8  alkyl; R 3  is selected from the group consisting of hydrogen and F; R 4  is selected from the group consisting of hydrogen or C 1-4  alkyl; or R 1  and R 4  are combined to form a 3- to 7-membered heterocycle ring as described above; R 5  is selected from the group consisting of F, Cl, C 1-8  alkyl, and C 3-8  cycloalkyl; L is C 1-6  alkylene; the subscript m represents the integer 0 or 1; X 1  and X 2  are each independently selected from the group consisting of absent and \u2014O\u2014, and wherein if the subscript m is 0 then one of X 1  or X 2  is absent; the ring \u201cA\u201d in is selected from the group consisting of: (i) C 2-11  heterocycle comprising a nitrogen atom and further optionally comprising 1-2 heteroatoms selected from N, O and S; wherein\n R AA  is independently selected from the group consisting of C 1-8  alkyl, C 1-8  haloalkyl, C 1-8  heteroalkyl, F, Cl, Br and I; \n n is an integer from 0 to 5; \n R A  is selected from the group consisting of (C 6-10  aryl) 1-2 -(X RA )\u2014, and (5- to 10-membered heteroaryl) 1-2 -(X RA )\u2014, wherein said C 6-10  aryl, 5- to 10 membered heteroaryl R A  is independently optionally substituted with from 1 to 5 R RA  substituents selected from the group consisting of F, Cl, C 1-4  haloalkyl, C 1-4  alkoxy and phenyl, wherein the R RA  substituent is optionally substituted with 1 to 5 R RAi  substituents selected from F and Cl; X RA  is selected from the group consisting of absent, \u2014O\u2014, \u2014S\u2014, \u2014N(H)\u2014, \u2014N(C 1-4  alkyl)-, \u2014S(O) 2 \u2014, \u2014C(\u2550O)\u2014, C 1-4  alkylene; and \n q is an integer from 0 to 1; \n (ii) C 3-12  membered carbocycle; wherein\n R A  is selected from the group consisting of C 1-8  alkyl, C 1-8  haloalkyl, F, and \u2014CN; \n n is the integer 0; and \n q is the integer 0 to 6; \n (iii) phenyl substituted at the 2-position, the 3,4-positions, the 2,4-positions, or the 3,5-positions with groups independently selected from R A , wherein each\n R A  is selected from the group consisting of Cl, \u2014OR A1 , 5- to 10 membered heteroaryl and phenyl; R A1  is C 1-8  haloalkyl; wherein each R A  substituent is optionally substituted with from 1 to 5 R RA  substituents selected from, \u2014NH 2 , and C 2-7  heterocyclyl that is optionally substituted with one or more C 1-4  alkoxycarbonyl; \n and (v) 5- to 10-membered heteroaryl comprising 1- to 3-nitrogen atoms and optionally further comprising 1- to 2-heteroatoms selected from O and S; wherein (v)\n R A  is selected from the group consisting of Cl, \u2014OR A1 , and C 3-6  cycloalkyl; wherein R A1  is C 1-8  haloalkyl; \n n is the integer 0; and \n q is an integer from 0 to 4.

Metadata:
- Claim Count in Document: 37.0
- Percentile: 97.0
- Lexical Diversity: 1.7551
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15321335', '15988956', '14772735', '14772726', '13899469']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8168973715943916
- 35 USC 102 Novelty (BERT): 0.5958886922038971
- Combined Prediction Score: 0.7947965036553422
- Mean Citation Score: 460.31907999999993
- Max Citation Score: 530.8615
- Similarity Product: 469.0796930169165

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test