PATENT CLAIM ANALYSIS

Application Number: 16276260
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["435", "007100"]

Abstract:
The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.

Claim (Index 2):
A method of determining spatial patterns of biological targets in a tissue sample, comprising:\n delivering encoded probes for a biological target to multiple sites in a tissue sample affixed to a support, wherein each encoded probe comprises an oligonucleotide-conjugated protein capable of specific binding to the biological target; allowing the encoded probes to interact with the biological target at each of the multiple sites in the tissue sample; separating encoded probes specifically bound to the biological target from encoded probes not specifically bound to the biological target; determining all or a portion of an oligonucleotide sequence corresponding to the oligonucleotide-conjugated protein; and identifying a spatial pattern of the biological target in the tissue sample using the oligonucleotide sequence of the oligonucleotide-conjugated protein.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 99.0
- Lexical Diversity: 1.48936
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15187661', '13080616', '16276235', '14900604', '14900602']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5833899307498999
- 35 USC 102 Novelty (BERT): 0.4994270798649808
- Combined Prediction Score: 0.574993645661408
- Mean Citation Score: 285.280014
- Max Citation Score: 322.30536
- Similarity Product: 289.98264243427275

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test