PATENT CLAIM ANALYSIS

Application Number: 15863498
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-07
Patent Classification: ["514", "183000"]

Abstract:
This invention describes the use of indane acetic acid derivatives which are dual PPAR delta/gamma agonists, and which penetrate the Blood Brain Barrier and achieve effective brain to plasma drug levels at non-toxic doses, for the treatment of neurodegenerative diseases including one or more of the following: Alzheimer's Disease (AD); Huntington's Disease (HD); Parkinson's Disease (PD); Amyotrophic Lateral Sclerosis (ALS); Frontal Temporal Dementia (FTD); Corticobasal Degeneration (CBD); Progressive Supranuclear Palsey (PSP); Dementia with Lewy Bodies (DLB); or Multiple Sclerosis (MS).

Claim (Index 25):
The method of treatment according to  claim 2  which further comprises one or more additional therapeutic agents elected from the group consisting of:\n a) a therapeutic agent used to treat Alzheimer's disease selected from the group consisting of Donepezil, Rivastigmine, or Memantine; \n b) a therapeutic agent used to treat Parkinson's Disease (PD) selected from the group consisting of L DOPA (levodopa), or dopamine agonists; \n c) a therapeutic agent used to treat Amyotrophic Lateral Sclerosis (ALS) selected from the group consisting of Edaravone (Radicut), or Riluzole; \n d) a therapeutic agent used to treat Multiple Sclerosis (MS) selected from the group consisting of interferon beta, glatiramer acetate, mitoxantrone, natalizumab, fingolimod, teriflunomide, alemtuzumab, daclizumab, or ocrelizumab; and \n e) a therapeutic agent used to treat Huntington's Disease (HD) is tetrabenazine.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 91.0
- Lexical Diversity: 1.50667
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15774638', '15830675', '15484445', '14429101', '14897396']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8035241422085322
- 35 USC 102 Novelty (BERT): 0.5015652778268964
- Combined Prediction Score: 0.7733282557703687
- Mean Citation Score: 249.04305400000004
- Max Citation Score: 259.62888
- Similarity Product: 188.72243295842168

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test