PATENT CLAIM ANALYSIS

Application Number: 15942587
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-02
Patent Classification: ["514", "04400A"]

Abstract:
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate expression of a p53 gene.

Claim (Index 40):
The method of  claim 39 , wherein the disease or disorder is selected from the group consisting of ischemia-reperfusion injury, a hearing impairment, a hearing disorder, a balance impairment, a hearing loss, chemotherapy-induced alopecia, radiation therapy-induced alopecia, an acute renal failure, an acute kidney injury, a chronic kidney disease (CKD), a side effect associated with anti-cancer therapy, Delayed Graft Function (DGF) in a kidney transplant patient, a spinal cord injury, a brain injury, a seizure, a stroke, a neurodegenerative disorder, Parkinson's disease, Alzheimer's disease, a tumor, a burn, a wound, hyperthermia, hypoxia, ischemia, organ transplantation, bone marrow transplantation (BMT), myocardial infarction/heart attack, cardiotoxicity, a p53-positive cancer, and acute liver failure

Metadata:
- Claim Count in Document: 20.0
- Percentile: 91.0
- Lexical Diversity: 1.26316
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14421845', '14426513', '13700942', '15433400', '13521033']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8456582793651427
- 35 USC 102 Novelty (BERT): 0.5877902783811076
- Combined Prediction Score: 0.8198714792667392
- Mean Citation Score: 425.007888
- Max Citation Score: 516.79877
- Similarity Product: 441.7857643677461

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test