PATENT CLAIM ANALYSIS

Application Number: 15864144
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["506", "009000"]

Abstract:
Methods for preparation of cells for analysis of biomarkers are disclosed. In one aspect, the method for preparation of cells for analysis of biomarkers includes contacting a sample that contains a population of cells with at least one modulating substance at a first temperature, thereby producing a modulated cell population; contacting the modulated cell population with at least one antibody that is directed to a cell surface biomarker at a second temperature that is lower than the first temperature, thereby producing an extracellularly stained cell population; and contacting the extracellularly stained cell population with one or more reagents that fixes and permeabilizes the cells, thereby producing a fixed and permeabilized cell population.

Claim (Index 5):
The method of  claim 4 , wherein the antibodies are directed to IL3R, IL7R, p-STAT5, p-STAT3, and p-p38 MAPK.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 86.0
- Lexical Diversity: 2.18182
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14073692', '12125763', '10898734', '12778847', '13098912']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5719396610868346
- 35 USC 102 Novelty (BERT): 0.5179027138472457
- Combined Prediction Score: 0.5665359663628757
- Mean Citation Score: 262.59957799999995
- Max Citation Score: 277.22623
- Similarity Product: 190.8243356705201

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test