PATENT CLAIM ANALYSIS

Application Number: 15886386
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "04400A"]

Abstract:
The present invention is related to a nucleic acid molecule comprising a double-stranded structure, wherein the double-stranded structure is formed by a first strand and a second strand, wherein the first strand consist of the following nucleotide sequence 5′ acGaGcUgGaCcAcUgGuCdT s dT 3′, and the second strand consists of the following nucleotide sequence 5′ GAcCaGuGgUcCaGcUcGudT s dT 3′, wherein a minor nucleotide indicates that the nucleotide is 2′-F modified and an underlined nucleotide indicates that the nucleotide is 2′-0-methyl modified and wherein dT s dT indicates that at the 3′ end a dinucleotide is attached consisting of two dT nucleotides, wherein said two dTs are covalently linked through a phosphorothioate bond.

Claim (Index 20):
The nucleic acid molecule of  claim 1 , for use in a method for the treatment and/or prevention of a disease, wherein the method comprises administering to a subject the nucleic acid molecule, preferably the disease is selected from the group comprising esophageal cancer, oral squamous cell carcinoma, head and neck cancer, tongue cancer, leukemia, renal cell carcinoma, gastric cancer, colon adenocarcinoma, endometrial cancer/uterine corpus, cervical cancer/uterine cervix, intrahepatic cholangiocarcinoma, hepatocellular carcinoma, osteosarcoma, urinary bladder carcinoma, malignant melanoma, thyroid cancer, lung adenocarcinoma, prostate cancer, breast cancer, ovarian cancer, pancreatic cancer and glioma.

Metadata:
- Claim Count in Document: 68.0
- Percentile: 88.0
- Lexical Diversity: 2.01724
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15026084', '14021353', '14780043', '15882221', '12307052']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7606969690229467
- 35 USC 102 Novelty (BERT): 0.5235495951089628
- Combined Prediction Score: 0.7369822316315483
- Mean Citation Score: 264.962306
- Max Citation Score: 332.684
- Similarity Product: 237.1274473690987

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test