PATENT CLAIM ANALYSIS

Application Number: 16198276
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["424", "001490"]

Abstract:
This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these binding proteins has one or more binding sites where each binding site binds with a target antigen or an epitope on a target antigen. Another embodiment of these binding proteins has two or more binding sites where each binding site has affinity towards different epitopes on a target antigen or has affinity towards either a target antigen or a hapten. The present invention further relates to recombinant vectors useful for the expression of these functional binding proteins in a host. More specifically, the present invention relates to the tumor-associated antigen binding protein designated RS7, and other EGP-1 binding-proteins. The invention further relates to humanized, human and chimeric RS7 antigen binding proteins, and the use of such binding proteins in diagnosis and therapy.

Claim (Index 11):
The composition of  claim 10 , wherein the radionuclide is selected from the group consisting of  131 I,  123 I,  124 I,  86 Y,  62 Cu,  64 Cu,  67 Ga,  68 Ga,  99m Tc,  94m Tc,  90 Y,  111 In,  125 I,  186 Re,  188 Re,  189 Re,  177 Lu,  67 Cu,  212 Bi,  213 Bi,  211 At,  198 Au,  224 Ac,  126 I,  133 I,  77 Br,  113m In,  95 Ru,  97 Ru,  103 Ru,  105 Ru,  107 Hg,  203 Hg,  121m Te,  125m Te,  165 Tm,  167 Tm,  168 Tm,  111 Ag,  197 Pt,  109 Pd,  32 P,  33 P,  47 Sc,  153 Sm,  105 Rh,  142 Pr,  143 Pr,  161 Tb,  166 Ho,  199 Au,  57 Co,  58 Co,  51 Cr,  59 Fe,  18 F,  75 Se,  201 Tl,  225 Ac,  76 Br,  86 Y,  169 Yb,  166 Dy,  212 Pb, and  223 Ra.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 98.0
- Lexical Diversity: 2.23188
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15980057', '14040024', '12389503', '15816635', '13293608']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8915031737203797
- 35 USC 102 Novelty (BERT): 0.6755464421182531
- Combined Prediction Score: 0.8699075005601671
- Mean Citation Score: 663.99236
- Max Citation Score: 668.4227
- Similarity Product: 616.1499050424577

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test