PATENT CLAIM ANALYSIS

Application Number: 15754508
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["424", "423000"]

Abstract:
Provided are a cell carrier for skin tissue regeneration using chitooligosaccharide and a method for producing the same. The cell carrier according to the present invention includes fish-derived collagen (FC), alginate (A), and chitooligosaccharide (COS1) of 1 to 3 kDa, and thus has excellent biocompatibility with dermal fibroblasts and has an excellent effect of being utilized as a cell carrier for skin tissue regeneration.

Claim (Index 1):
A method of preparing a cell carrier for skin tissue regeneration, the method comprising the steps of:\n (a) dissolving fish-derived collagen and alginate in 0.02 M acetic acid to prepare collagen-alginate (FCA) solution in a weight ratio (w/w) of 70:30; (b) freeze-drying the FCA solution obtained in step (a) to prepare a collagen-alginate (FCA) scaffold; (c) immersing the FCA scaffold obtained in step (b) in a cross-linker solution for 3 to 5 hours to cross-link the same; (d) adding 1 to 3 kDa chitooligosaccharide (COS1) in an amount of 0.5 to 5% (w/w) with respect to the total weight of the cross-linker solution and cross-linking the same for 20 to 30 hours while the FCA scaffold of step (c) is immersed in the cross-linker solution; and (e) immersing the FCA/COS1 cell carrier obtained in step (d) in distilled water for 48 hours, washing the cell carrier, and then freeze-drying the cell carrier.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 88.0
- Lexical Diversity: 1.5625
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15326638', '15169521', '14360910', '12744512', '12304907']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6417049233940205
- 35 USC 102 Novelty (BERT): 0.4761405554041767
- Combined Prediction Score: 0.6251484865950361
- Mean Citation Score: 147.057886
- Max Citation Score: 149.35675
- Similarity Product: 109.90583462646605

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test