PATENT CLAIM ANALYSIS

Application Number: 15868721
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["424", "093700"]

Abstract:
Various embodiments of the present invention include compositions, materials and methods for maintaining and propagating mammalian mesenchymal stem cells in an undifferentiated state in the absence of feeder cells and applications of the same.

Claim (Index 60):
A method of generating bone in a patient in need thereof comprising:\n (i) obtaining mammalian mesenchymal stem cells; (ii) producing a bone forming composition by culturing said mammalian mesenchymal stem cells in vitro on a three-dimensional marrow stromal cell derived extracellular matrix, isolating undifferentiated mammalian mesenchymal stem cells from said culture, and combining said undifferentiated mammalian mesenchymal stem cells with a transplantation vehicle; and (iii) administering said bone forming composition to said patient; wherein said extracellular matrix comprises type I collagen, type II collagen, type V collagen, syndecan-1, fibronectin, decorin, biglycan, perlecan, and laminin.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.28571
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13762887', '13297966', '11625763', '14596777', '13821288']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8397246184416501
- 35 USC 102 Novelty (BERT): 0.6884119566705427
- Combined Prediction Score: 0.8245933522645394
- Mean Citation Score: 689.7419
- Max Citation Score: 750.9746
- Similarity Product: 698.0713877495648

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test