PATENT CLAIM ANALYSIS

Application Number: 16020773
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-04
Patent Classification: ["424", "046000"]

Abstract:
Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route, the method comprising covalently conjugating a hydrophilic polymer to a drug, wherein the drug has a half-life of elimination from the lung of less than about 180 minutes, to form a drug-polymer conjugate, wherein the drug-polymer conjugate has a net hydrophilic character and a weight average molecular weight of from about 50 to about 20,000 Daltons, and wherein the half-life of elimination from the lung of the drug-polymer conjugate is at least about 1.5-fold greater than the half-life of elimination from the lung of the drug, wherein the half-life of elimination from the lung is measured by bronchioalveolar lavage followed by assaying residual lung material.

Claim (Index 51):
The pharmaceutical compound according to  claim 39 , wherein the drug is a fluoroquinolone selected from the group consisting of ciprofloxacin, ofloxacin, levofloxacin, trovafloxacin, alatrofloxacin, moxifloxicin, norfloxacin, enoxacin, grepafloxacin, gatifloxacin, lomefloxacin, sparfloxacin, temafloxacin, pefloxacin, amifloxacin, fleroxacin, tosufloxacin, prulifloxacin, irloxacin, pazufloxacin, clinafloxacin and sitafloxacin.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 94.0
- Lexical Diversity: 2.25862
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12710167', '14248245', '11015196', '12822935', '10808044']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8118789797273236
- 35 USC 102 Novelty (BERT): 0.548225480489625
- Combined Prediction Score: 0.7855136298035538
- Mean Citation Score: 365.409304
- Max Citation Score: 478.04288
- Similarity Product: 265.5611545529175

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test