PATENT CLAIM ANALYSIS

Application Number: 15877597
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "052000"]

Abstract:
The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

Claim (Index 59):
A method of treating a disease or disorder associated with NAD+ biosynthesis, comprising administering a compound, or a salt thereof, to a subject in need thereof, wherein the compound has a structure represented by formula I: wherein V is selected from hydrogen, phenyl and monocyclic heteroaryl, wherein (i) each said monocyclic heteroaryl contains five or six ring atoms of which 1 or 2 ring atoms are heteroatoms selected from N, S, and O, and the remainder of the ring atoms are carbon, and (ii) each said phenyl or monocyclic heteroaryl is unsubstituted or is substituted by one or two groups independently selected from halogen, trifluoromethyl, C 1 -C 6  alkyl, C 1 -C 6  alkoxy, and cyano; and wherein the disease or disorder is a mitochondrial disease or disorder.

Metadata:
- Claim Count in Document: 119.0
- Percentile: 86.0
- Lexical Diversity: 1.81818
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15512388', '15492952', '15562336', '13991321', '13991328']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7218735505094714
- 35 USC 102 Novelty (BERT): 0.59645682039074
- Combined Prediction Score: 0.7093318774975983
- Mean Citation Score: 314.0314259999999
- Max Citation Score: 537.07587
- Similarity Product: 421.7324608400882

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test