PATENT CLAIM ANALYSIS

Application Number: 16219589
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["514", "210180"]

Abstract:
The subject matter generally relates to methods of treatment and/or prophylaxis of CNS diseases, disorders, and/or injuries. In one aspect, the subject matter relates to inhibitors of phosphodiesterase 1 (PDE1) as neuroprotective agents and/or neural regenerative agents. In a further aspect, the subject matter relates to individuals that are at risk for the development of CNS disease or disorder.

Claim (Index 7):
A method of  claim 1 , wherein the PDE1 inhibitor is compound of Formula VI: wherein:\n (i) R 1  is H or alkyl; \n (ii) R 2  is H, alkyl, cycloalkyl, haloalkyl, alkylaminoalkyl, hydroxyalkyl, arylalkyl, heteroarylalkyl, or alkoxyarylalkyl; \n (iii) R 3  is heteroarylmethyl or formula A \n wherein X, Y and Z are, independently, N or C, and R 8 , R 9 , R 11  and R 12  are independently H or halogen; and R 10  is halogen, alkyl, cycloalkyl, haloalkyl, aryl, heteroaryl, alkyl sulfonyl, arylcarbonyl, heteroarylcarbonyl, alkoxycarbonyl, or aminocarbonyl;\n (iv) R 4  is aryl or heteroaryl; and \n (v) R 5  is H, alkyl, cycloalkyl, heteroaryl, aryl, p-benzylaryl; \n provided that when X, Y or X is nitrogen, R 8 , R 9  or R 10 , respectively, is not present; wherein \u201calk\u201d or \u201calkyl\u201d refers to C 1-6  alkyl and \u201ccycloalkyl\u201d refers to C 3-6  cycloalkyl, in free, salt or physiologically hydrolysable and acceptable ester prodrug form.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.54545
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14777448', '15406346', '14767489', '15709258', '14820323']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7848041217949886
- 35 USC 102 Novelty (BERT): 0.5459831251125686
- Combined Prediction Score: 0.7609220221267466
- Mean Citation Score: 348.187806
- Max Citation Score: 492.94012
- Similarity Product: 340.8203813861918

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test