PATENT CLAIM ANALYSIS

Application Number: 16005605
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "235800"]

Abstract:
This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably α-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.

Claim (Index 11):
A method of treating an ocular condition comprising the step of: administering to the eye of a subject in need thereof an eye drop formulation consisting of (a) at least one active agent or pharmaceutically acceptable salt thereof for the treatment of an ocular condition, dissolved, dispersed, or suspended in (b) at least one biocompatible, biodegradable, non-polymeric excipient comprising (i) a tocopherol or tocotrienol selected from d, l and dl isomers of \u03b1, \u03b2, \u03b4, \u03f5, \u03b7 tocopherol and tocotrienol, the esters of tocopherol or tocotrienol with straight and branched chain C2 to C20 aliphatic acids, and the esters of tocopherol or tocotrienol with C3 to C20 straight chain dicarboxylic acids, wherein said tocopherol or tocotrienol is at least 50% (wt %) of the formulation, and, optionally, (ii) at least one pharmaceutically acceptable non-polymeric hydrophobic carrier; wherein the administration of a unit dose of a single eye drop provides sustained release of the active agent to the eye for at least 4 days.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 94.0
- Lexical Diversity: 1.31707
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13963574', '15017547', '12236877', '13006801', '11236426']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8292002070518669
- 35 USC 102 Novelty (BERT): 0.5759219765330176
- Combined Prediction Score: 0.803872383999982
- Mean Citation Score: 460.26974400000006
- Max Citation Score: 518.5319
- Similarity Product: 386.8637049959778

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test