PATENT CLAIM ANALYSIS

Application Number: 15925083
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["514", "04400A"]

Abstract:
Compositions and methods for modifying genetic material are provided. One embodiment provides aptamers capable of binding to a site-specific DNA binding moiety to facilitate the exchange of homologous genetic information between a donor molecule and the desired target locus (aptamer-guided gene targeting or AGT). One embodiment provides an oligonucleotide containing a aptamer, preferably a DNA aptamer at the 5′ end. The oligonucleotide also contains a region of homology, also referred to as donor DNA, to a desired nucleic acid, locus, or gene. The DNA binding moiety can be a nucleic acid, a protein, or a complex of proteins. In a preferred embodiment the DNA binding moiety is a homing endonuclease that cuts DNA to facilitate the modification of the DNA by the donor DNA.

Claim (Index 13):
The method of  claim 12 , wherein the aptamer is specific for a homing endonuclease expressed by the subject.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 1.93056
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14802832', '10484989', '10384918', '13556206', '12753016']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7662222288856793
- 35 USC 102 Novelty (BERT): 0.5893600482789808
- Combined Prediction Score: 0.7485360108250094
- Mean Citation Score: 352.356134
- Max Citation Score: 640.46045
- Similarity Product: 388.2613508990081

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test