PATENT CLAIM ANALYSIS

Application Number: 16377344
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["435", "006100"]

Abstract:
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.

Claim (Index 32):
The method of  claim 17 , wherein the composition includes one or more protease inhibiting compounds selected from antipain, aprotinin, chymostatin, elastatinal, phenylmethylsulfonyl fluoride (PMSF), APMSF, TLCK, TPCK, leupeptin, soybean trypsin inhibitor, indoleacetic acid (IAA), E-64, pepstatin, VdLPFFVdL, EDTA, 1,10-phenanthroline, phosphoramodon, amastatin, bestatin, diprotin A, diprotin B, alpha-2-macroglobulin, lima bean trypsin inhibitor, pancreatic protease inhibitor, egg white ovostatin, egg white cystatin and any combination thereof.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 100.0
- Lexical Diversity: 1.6
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15894077', '15937446', '15601682', '14071969', '12704030']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.677528847504164
- 35 USC 102 Novelty (BERT): 0.5757323819477546
- Combined Prediction Score: 0.667349200948523
- Mean Citation Score: 355.55956000000015
- Max Citation Score: 413.49518
- Similarity Product: 262.5721464422679

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test