PATENT CLAIM ANALYSIS

Application Number: 16060250
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["544", "278000"]

Abstract:
The present invention relates to a novel dihydropyranopyrimidinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Claim (Index 1):
A compound represented by Chemical Formula 1, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof: wherein, X is CHR 4  or C\u2550O; Y is N or C; l is 0, 1 or 2; R 1  is hydrogen, hydroxyl, cyano or C 1-6  alkyl {herein, if Y is N, R 1  is null}; R 2  is heteroaryl or heterocyclyl;\n R 4  is hydrogen, hydroxyl, C 1-6  alkyl or amino; \n m is 0, 1, 2 or 3; \n n is 0, 1, 2, 3, 4 or 5; \n each of R 5  is independently \u2014Z\u2014(CH 2 ) p \u2014R 6 , halo, cyano, nitro, carboxy, C 1-6  alkyl, C 1-6  alkyloxo, C 2-6  alkenyl, C 1-6  alkoxy, C 1-6  alkoxycarbonyl, C 1-6  hydroxyalkyl, C 1-6  dihydroxyalkyl, C 1-6  haloalkyl unsubstituted or optionally substituted with hydroxyl or C 3-7  cycloalkyl; \n Z is \u2014O\u2014, \u2014S(O) q \u2014, \u2014NR 7 \u2014, \u2014CONR 7 \u2014, \u2014CHR 7 \u2014 or null; \n p is 0, 1, 2, 3, 4, 5 or 6; \n q is 0, 1 or 2; \n R 6  is hydrogen, hydroxyl, \u2014OR 8 , \u2014O\u2014(C\u2550O)\u2014R 8 , \u2014S(O) r \u2014R 8 , cyano, \u2014(C\u2550O)\u2014R 8 , \u2014(C\u2550O)OR 8 , \u2014(C\u2550O)NR 9 R 10 , \u2014NR 9 R 10 , azido, C 1-6  alkyl, C 1-6  dihydroxyalkyl, C 1-6  haloalkyl unsubstituted or optionally substituted with hydroxyl, C 3-7  cycloalkyl, heterocyclyl, C 5-10  aryl or heteroaryl; \n r is 0, 1 or 2; \n R 7  is hydrogen, C 1-6  alkyl, C 1-6  alkoxy, C 3-7  cycloalkyl or C 1-3  alkyl-C 3-7  cycloalkyl; \n R 8  is hydrogen, C 1-6  alkyl, C 1-6  alkyloxo, C 1-6  alkoxy, amino, C 1-6  alkylamino, C 1-6  aminoalkyl, C 3-7  cycloalkyl, C 1-3  alkyl \u2014C 3-7  cycloalkyl or heterocyclyl; \n each of R 9  and R 10  is independently hydrogen, C 1-6  alkyl, C 1-6  alkoxy, C 3-6  cycloalkyl, C 1-3  alkyl-C 3-6  cycloalkyl or \u2014(SO 2 )\u2014C 1-3  alkyl; \n each of the heteroaryls is a 5- to 10-membered single or fused ring containing one or more heteroatoms selected from the group consisting of N, O, S and a combination thereof, and each of the heterocyclyls is a 3- to 10-membered single or fused ring containing one or more heteroatoms selected from the group consisting of N, O, S and a combination thereof; \n one or more than one hydrogen of each of the cycloalkyls and heterocyclyls may be unsubstituted or substituted with hydroxyl, oxo, halo, cyano, nitro, C 1-6  alkyl, C 1-6  hydroxyalkyl, C 1-6  haloalkyl, C 1-6  alkoxy, formyl, C 1-6  alkylformyl, carboxy, C 1-6  alkylcarboxy, amino, C 1-6  alkylamino, di(C 1-6  alkyl)amino, carbamoyl, C 1-6  alkylcarbamoyl or di(C 1-6  alkyl)carbamoyl; and \n one or more than one hydrogen of each of the aryls and heteroaryls may be unsubstituted or substituted with hydroxyl, oxo, halo, cyano, nitro, C 1-6  alkyl, C 1-6  alkoxy, C 1-6  hydroxyalkyl, C 1-6  haloalkyl, pyrazinyl, formyl, C 1-6  alkylformyl, carboxy, C 1-6  alkylcarboxy, amino, C 1-6  alkylamino, di(C 1-6  alkyl)amino, carbamoyl, C 1-6  alkylcarbamoyl, di(C 1-6  alkyl)carbamoyl or C 1-6  alkylsulfonyl.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.32432
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15325651', '15325692', '14154161', '14154173', '14154170']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8079111707883919
- 35 USC 102 Novelty (BERT): 0.5569865106340532
- Combined Prediction Score: 0.7828187047729581
- Mean Citation Score: 369.913976
- Max Citation Score: 422.80225
- Similarity Product: 378.817597179845

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test