PATENT CLAIM ANALYSIS

Application Number: 15982038
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "249000"]

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Claim (Index 10):
The compound of  claim 9 , having Formula (X): or a stereoisomer, tautomer, pharmaceutically acceptable salt thereof, wherein: L is selected from the group consisting of: \u2014CH\u2550CH\u2014 and \u2014C\u2261C\u2014; R 1a  is selected from the group consisting of: H, halo, C 1-2  alkyl, and methoxy; R 1b  is selected from the group consisting of: H and halo; R 2  is selected from the group consisting of: H, F, CN, OH, C 1-4  alkoxy, \u2014CHF 2 , \u2014CF 3 , \u2014CH 2 NH 2 , \u2014OCHF 2 , \u2014CO(C 1-4  alkyl), \u2014CONH 2 , \u2014COOH, triazole substituted with R 2a , and tetrazole substituted with R 2a ; R 3  is selected from the group consisting of: phenyl substituted with 1-2 R 3a , C 3-6  cycloalkyl substituted with 1-2 R 3a , pyridyl substituted with 1-2 R 3a , R 3a , at each occurrence, is selected from the group consisting of: \u2550O, F, Cl, C 1-4  alkyl, \u2014OH, \u2014O(C 1-4  alkyl), \u2014CN, \u2014NH 2 , \u2014CO 2 H, \u2014CO 2 (C 1-4  alkyl), \u2014CONHCO 2 (C 1-4  alkyl), \u2014NHCOC 1-4  alkyl, \u2014(CH 2 ) n NHCO 2 (C 1-4  alkyl), and R c ; R 4a , R 4b , R 4c , and R 4d  are independently selected from the group consisting of: H, F, and C 1-4  alkyl; R 5  is selected from the group consisting of: H, halo, C 1-4  alkyl \u2014CN, \u2014O(C 1-4  alkyl), \u2014O\u2014C 1-4  alkylene-O(C 1-4  alkyl), \u2014CO 2 (C 1-4  alkyl), \u2014OR 8 , \u2014CONR 9 R 8 , and \u2014NR 9 CO 2 R 8 ; R 8  is \u2014(CH 2 ) n -phenyl; R c  is \u2014(CH 2 ) n -5- to 6-membered heterocycle containing carbon atoms and 1-4 heteroatoms selected from the group consisting of N, NH, N(CO 2 Me), O, and S; and n, at each occurrence, is selected from 0, 1, 2, and 3;

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.17949
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15643891', '15183051', '14799681', '14350411', '14350417']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8312592625522399
- 35 USC 102 Novelty (BERT): 0.5119385924955628
- Combined Prediction Score: 0.7993271955465723
- Mean Citation Score: 315.033496
- Max Citation Score: 316.3271200000001
- Similarity Product: 276.07824106095325

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test