PATENT CLAIM ANALYSIS

Application Number: 15889800
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["435", "006140"]

Abstract:
Methods for analyzing the bacterial microbiome of a subject and triaging the subject into treatment for head and neck squamous cell cancer from a saliva or tissue sample are provided. The methods also provide means for differentiation of different cancer patient cohorts from the bacterial microbiome of a subject.

Claim (Index 11):
A method of triaging a subject having Head and Neck Squamous Cell Cancer (HNSCC) into treatment for oropharyngeal squamous cell cancer (OPSCC) comprising the steps of:\n a) obtaining a biological sample from the subject; b) isolating the nucleic acid in the sample; c) amplifying the 16S rRNA V3-V5 gene region of bacterial nucleic acid present in the sample of b) using specific primers and probes for the 16S rRNA V3-V5 region; d) sequencing the amplified DNA of step c); e) identifying the bacterial species present in the sample using high-resolution profiling of the sequences of step d); f) triaging the subject into treatment for OPSCC when one or more bacterial species selected from the group consisting of  Lactobacillus gasseri , and  Lactobacillus johnsonii.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 88.0
- Lexical Diversity: 1.45714
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14759918', '14196999', '14270805', '14775722', '14777252']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.542946378308783
- 35 USC 102 Novelty (BERT): 0.4937248356413152
- Combined Prediction Score: 0.5380242240420362
- Mean Citation Score: 257.974896
- Max Citation Score: 265.53662
- Similarity Product: 216.0901183782005

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test