PATENT CLAIM ANALYSIS

Application Number: 16096119
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["514", "023000"]

Abstract:
Disclosed are an amine solvate of a sodium-glucose linked transporter (SGLT) inhibitor, and a preparation method and application thereof. The SGLT inhibitor is (1S,2S,3S,4R,5S)-5-(3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-ethylbenzyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Further provided is a crystalline compound of the amine solvate, a pharmaceutical composition comprising the amine solvate, and an application of the amine solvate in preparing an SGLT-inhibiting pharmaceutical product.

Claim (Index 7):
The process for preparing the amine solvate of the compound of formula (I) according to  claim 6 , wherein the amine reagent in step 1) is a pure liquid amine reagent, an aqueous amine reagent or a mixture of an amine reagent and an organic solvent, and the amine reagent is selected from the group consisting of methylamine, dimethylamine, ethylamine, diethylamine, propylamine, dipropylamine, tripropylamine, 1,2-dimethylpropylamine, cyclopropylamine, diisopropylamine, triethylamine, n-butylamine, isobutylamine, tert-butylamine, sec-butylamine, diisobutylamine, hexylamine, dicyclohexylamine, decylamine, dodecylamine, triethanolamine, allylamine, ethanolamine, 3-propanolamine, isopropanolamine, diisopropanolamine, triisopropanolamine, dimethylethanolamine, diethylethanolamine, ethylenediamine, 1,3-propanediamine, 1,4-butanediamine, 1,5-pentanediamine, 1,6-hexanediamine, morpholine and piperazine.

Metadata:
- Claim Count in Document: 10.0
- Percentile: 97.0
- Lexical Diversity: 1.78431
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15778220', '15748283', '15314458', '16065544', '15753993']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7833400872576707
- 35 USC 102 Novelty (BERT): 0.5210733143242662
- Combined Prediction Score: 0.7571134099643303
- Mean Citation Score: 275.562144
- Max Citation Score: 309.48706
- Similarity Product: 236.1350516297412

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test