PATENT CLAIM ANALYSIS

Application Number: 16218588
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-09
Patent Classification: ["514", "04400A"]

Abstract:
The invention relates to methods, processes and apparatuses for the manufacture of lipid nanoparticles having a therapeutic payload.

Claim (Index 11):
A system for the manufacture of a formulation comprising lipid nanoparticles comprising an RNAi agent payload comprising;\n (a) a first reservoir providing a first solution, wherein said first solution is an ethanolic solution comprising one or more lipids, (b) a second reservoir providing a second solution, wherein said second solution is a buffered aqueous solution comprising one or more RNAi agents, (c) a first pump, operably connected to said first reservoir and configured to regulate the flow of said first solution at a linear flow rate of between 303,133 and 909,400 cm/h, (d) a second pump, operably connected to said second reservoir and configured to regulate the flow of said second solution at a linear flow rate of between 1,515,667 and 2,121,934 cm/h, (e) a mixing connector comprising at least a first inlet, a second inlet and an outlet, wherein said first inlet receives flow from said first pump and said second inlet receives flow from said second pump, (f) at least one heat exchanger operably connecting each of said first and said second pumps to said inlets of the mixing connector, respectively, and (g) a vessel for receiving effluent from the outlet of said mixing connector.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 98.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15023919', '15326291', '13669217', '11495150', '12965555']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7110123168807597
- 35 USC 102 Novelty (BERT): 0.5558353319998555
- Combined Prediction Score: 0.6954946183926694
- Mean Citation Score: 219.232654
- Max Citation Score: 413.18713
- Similarity Product: 400.40750551157663

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test