PATENT CLAIM ANALYSIS

Application Number: 16420544
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-09
Patent Classification: ["514", "278000"]

Abstract:
The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating MAGL-mediated diseases and disorders including, e.g., pain, an inflammatory disorder, depression, anxiety, Alzheimer's disease, a metabolic disorder, stroke, or cancer.

Claim (Index 22):
The method of  claim 1 , wherein the compound is selected from the group consisting of:\n (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]-1-oxa-8-azaspiro[4.5]decane-8-carboxylate, DIAST 2; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl (3R)-3-(4-fluoro-1H-pyrazol-1-yl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl (3S)-3-(3-cyanophenyl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 3-[6-(trifluoromethyl) pyridin-2-yl]-1-oxa-8-azaspiro[4.5]decane-8-carboxylate, DIAST 1; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 2-{[6-(difluoromethyl)pyridin-3-yl]oxy}-7-azaspiro[3.5]nonane-7-carboxylate; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 3-(5-cyano-2-fluorophenyl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate, DIAST 2; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 3-[4-(difluoromethyl)pyridin-2-yl]-1-oxa-8-azaspiro[4.5]decane-8-carboxylate, DIAST 1; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 2-[5-(difluoromethyl)pyridin-2-yl]-7-azaspiro[3.5]nonane-7-carboxylate; (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 2-(4-cyclopropyl-1H-pyrazol-1-yl)-7-azaspiro[3.5]nonane-7-carboxylate; and (2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl 2-(3-fluorophenoxy)-7-azaspiro[3.5]nonane-7-carboxylate, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 100.0
- Lexical Diversity: 1.52
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15874987', '15221658', '15808242', '14652150', '14902324']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8334612144685252
- 35 USC 102 Novelty (BERT): 0.6031408272603015
- Combined Prediction Score: 0.8104291757477028
- Mean Citation Score: 395.616206
- Max Citation Score: 519.7040400000002
- Similarity Product: 501.3813397229149

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test