PATENT CLAIM ANALYSIS

Application Number: 16030046
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["514", "233200"]

Abstract:
Disclosed are methods for treating cancers associated with rearrangements in the mixed lineage leukemia gene (MLL-r), including MLL-r leukemia. The methods typically include administering a therapeutic amount of one or more therapeutic agents that inhibit the biological activity of one or more members of the interleukin-1 signaling pathway such inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4).

Claim (Index 16):
A compound having a formula IV: wherein R 1 , R 2 , R 3 , R 4 , and R 5  are the same or different and each of R 1 , R 2 , R 3 , R 4 , and R 5  is independently \u2014(CH 2 ) m R\u2032, wherein m is 0-6 and R\u2032 is selected from hydrogen, halo, amino or alkyl-substituted amino, hydroxyl, cyano, nitro, alkyl which may be straight chain or branched, allyl, alkoxy which may be straight chain or branched, saturated or unsaturated cycloalkyl which optionally is substituted with alkyl, halo, hydroxyl, or amino, and saturated or unsaturated heterocycloalkyl which optionally is substituted with alkyl, halo, hydroxyl, or amino; wherein R 6 , R 7 , R 8 , R 9 , and R 10  are the same or different and each of R 5 , R 6 , R 7 , R 8 , R 9 , and R 10  is independently \u2014(CH 2 ) n R\u2033, wherein n is 0-6 and R\u2033 is selected from hydrogen, halo, amino or alkyl-substituted amino, hydroxyl, cyano, nitro, alkyl which may be straight chain or branched, allyl, alkoxy which may be straight chain or branched, saturated or unsaturated cycloalkyl which optionally is substituted with alkyl, halo, hydroxyl, or amino, and saturated or unsaturated heterocycloalkyl which optionally is substituted with alkyl, halo, hydroxyl, or amino; and optionally at least one of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10  is not hydrogen, optionally at least one of R 1 , R 2 , R 3 , R 4 , and R 5  is halo or alkyoxy, or optionally at least one of R 6 , R 7 , R 8 , R 9 , and R 10  is amino, alkyl-substituted amino, dialkyl-substituted amino, amido, cyano, nitro, hydroxyl, or halo.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 95.0
- Lexical Diversity: 1.34043
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15497783', '14302219', '13991321', '15748536', '14773686']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7769314395691496
- 35 USC 102 Novelty (BERT): 0.704219164041823
- Combined Prediction Score: 0.7696602120164169
- Mean Citation Score: 410.139042
- Max Citation Score: 797.1224
- Similarity Product: 714.677049346447

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test