PATENT CLAIM ANALYSIS

Application Number: 16267404
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-05
Patent Classification: ["536", "024330"]

Abstract:
The present disclosure provides compositions (i.e., amplification primers and probes), methods, and kits that are particularly useful for detecting and/or quantifying nucleic acids present in a sample, such as those derived from HIV or a lentiviral vector.

Claim (Index 19):
A method of detecting a lentiviral nucleic acid and/or a HIV nucleic acid in a sample, the method comprising: (a) performing multiplex real-time PCR with a lentiviral nucleic acid template and a HIV nucleic acid template in the sample using: (i) a first forward primer having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 2, a first reverse primer having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 6, and a first probe having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 14, the first probe having a first reporter moiety; (ii) a second forward primer having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 4, a second reverse primer having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 6, and a second probe having a nucleotide sequence having at least 80% identity to that of SEQ ID NO: 8, the second probe having a second reporter moiety, where the first and second reporter moieties are different; (b) detecting an amplicon generated by (i) the first forward and reverse primers, and (ii) the second forward and reverse primers; and wherein detecting comprises detecting first and second signals from the first and second reporter moieties.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 99.0
- Lexical Diversity: 1.15789
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15810254', '13749319', '11683962', '14652335', '14254771']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6013725636074564
- 35 USC 102 Novelty (BERT): 0.6721971761255077
- Combined Prediction Score: 0.6084550248592615
- Mean Citation Score: 429.293422
- Max Citation Score: 789.5353
- Similarity Product: 628.3579108407497

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test