PATENT CLAIM ANALYSIS

Application Number: 15884915
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "676000"]

Abstract:
The present invention relates to a method of treating or preventing cellular dysfunction and death caused by genetic, degenerative, toxic, traumatic, ischemic, infectious, neoplastic and inflammatory diseases and aging—and their neurological symptoms and manifestations, which includes administering d-methadone, beta-d-methadol, alpha-l-methadol, beta-l-methadol, alpha-d-methadol, acetylmethadol, d-alpha-acetylmethadol, l-alpha-acetylmethadol, beta-d-acetylmethadol, beta-l-acetylmethadol, d-alpha-normethadol, l-alpha normethadol, noracetylmethadol, dinoracetylmethadol, methadol, normethadol, dinormethadol, EDDP, EMDP, d-isomethadone, normethadone, N-methyl-methadone, N-methyl-d-methadone, N-methyl-l-methadone, l-moramide, levopropoxyphene, pharmaceutically acceptable salts, or mixtures thereof, including deuterated and tritium analogues, whether isolated from its enantiomer or synthesized de novo.

Claim (Index 24):
A method for treating or preventing a condition including nervous system disorders, endocrine-metabolic disorders, cardiovascular disorders, age-related disorders, eye diseases, skin diseases, or symptoms and manifestations thereof, or for improving cognitive function, the method comprising:\n administering to a subject a substance chosen from d-isomethadone, l-moramide, levopropoxyphene, metabolites thereof, and combinations thereof; wherein the substance is isolated from its enantiomer or synthesized de novo; and wherein the administering of the substance occurs under conditions effective for the substance to:\n (a) regulate the levels of brain-derived neurotrophic factor (BDNF) or testosterone in the subject, \n (b) bind to an NMDA receptor, a NET, or a SERT of the subject or \n (c) modulate K + , Ca 2+ , or Na +  currents of cells of the subject.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 1.53165
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13803375', '15204052', '11527757', '13344393', '15579461']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.767367401440989
- 35 USC 102 Novelty (BERT): 0.5434440768813256
- Combined Prediction Score: 0.7449750689850226
- Mean Citation Score: 297.347038
- Max Citation Score: 403.17282
- Similarity Product: 292.49709374798664

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test