PATENT CLAIM ANALYSIS

Application Number: 16098288
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["424", "133100"]

Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

Claim (Index 15):
The compound of  claim 1  that is\n N-((1-(6-Fluoroquinolin-4-yl)piperidin-4-yl)methyl)-2-(p-tolyl)acetamide; \n 2-(4-Fluorophenyl)-N-((1-(6-fluoroquinolin-4-yl)piperidin-4-yl)methyl)acetamide; \n 2-(2-Fluorophenyl)-N-((1-(6-fluoroquinolin-4-yl)piperidin-4-yl)methyl)acetamide; \n 4-chloro-N\u2014((R)-2-((cis)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propyl)benzamide; \n 2-(4-chlorophenyl)-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)acetamide; \n 2-(2-chlorophenyl)-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)acetamide; \n 2-(3-chlorophenyl)-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)acetamide; \n (S)\u2014N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-2-phenylpropanamide; \n (R)\u2014N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-2-phenylpropanamide; \n N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-2-(4-methoxyphenyl)acetamide; \n (R)\u2014N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-2-methoxy-2-phenylacetamide; \n 2-(2-fluorophenyl)-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)acetamide; \n 1-(4-chlorophenyl)-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclobutanecarboxamide; \n 4-chloro-N\u2014((R)-1-((cis)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)bicyclo [2.2.2]octane-1-carboxamide; \n N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclohexanecarboxamide; \n N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclopropanecarboxamide; \n 3,3-difluoro-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclobutanecarboxamide; \n (1r,3R)-3-fluoro-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclobutanecarboxamide; \n (1s,3S)-3-fluoro-N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclobutanecarboxamide; \n N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)cyclobutanecarboxamide; \n (1s,4S)\u2014N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-4-hydroxycyclohexanecarboxamide; or \n (1r,4R)\u2014N\u2014((R)-1-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)ethyl)-4-hydroxycyclohexanecarboxamide; \n or a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a tautomer thereof, or a solvate thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.24324
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16098260', '16098239', '16098257', '14933863', '14933879']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7607239474395446
- 35 USC 102 Novelty (BERT): 0.5616305150651256
- Combined Prediction Score: 0.7408146042021028
- Mean Citation Score: 390.402226
- Max Citation Score: 427.52084
- Similarity Product: 354.41719554077866

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test