PATENT CLAIM ANALYSIS

Application Number: 16304634
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-09
Patent Classification: ["540", "575000"]

Abstract:
Relating to processes for preparing suvorexant or its pharmaceutically acceptable salts through the formation of a cocrystal of (R)-benzyl 5-methyl-1,4-diazepane-1-carboxylate hydrochloride with (R)-(+)-1,1,2-triphenyl-1,2-ethanediol ((R)-TED). This cocrystal provides the resolution of an intermediate of suvorexant, in particular, of (rac)-benzyl5-methyl-1,4-diazepane-1-carboxy-lateor a hydrochloride salt thereof. It also relates to a new cocrystal useful in such preparation processes.

Claim (Index 9):
The resolution process according to  claim 5 , wherein step b) comprises dissociating the cocrystal to yield (R)-benzyl 5-methyl-1,4-diazepane-1-carboxylate hydrochloride salt, if desired converting the salt into its free base of formula (R)-(III) and, if desired, converting the compound thus obtained to a salt thereof by reacting it with an appropriate acid

Metadata:
- Claim Count in Document: 19.0
- Percentile: 98.0
- Lexical Diversity: 1.60417
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16073929', '15501295', '12061499', '13147337', '10536618']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.657433892839918
- 35 USC 102 Novelty (BERT): 0.5133615997243355
- Combined Prediction Score: 0.6430266635283598
- Mean Citation Score: 238.975446
- Max Citation Score: 276.726
- Similarity Product: 224.92770637500288

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test