PATENT CLAIM ANALYSIS

Application Number: 15755558
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "468000"]

Abstract:
A derivative of  inula lineariifolia  lactone A, and in particular, a dimethylamine 4-O-acetyl  inula lineariifolia  lactone A or a salt thereof, preparation of same, and an application of same in preparation of medicine for treating multiple sclerosis. The dimethylamine 4-O-acetyl  inula lineariifolia  lactone A compound is represented by formula I:

Claim (Index 8):
The preparation methods of dimethylamine 4-O-acetyl  inula lineariifolia  lactone A compound and its pharmaceutically acceptable salt of  claim 6 , wherein a ratio of the dimethy-4-O-acetyl  inula lineariifolia  lactone A compound (compound I) and the acid (HX) is 1.0eq:1.0-1.5eq in the step (II) of preparation of the salt of the compound I;\n the acid (HX) is hydrochloric acid (HCl), sulfuric acid (H 2 SO 4 ), hydrofluoric acid (HF), hydrobromic acid (HBr), hydroiodic acid (HI), phosphoric acid (H 3 PO 4 ), sulfurous acid (H 2 SO 3 ), nitric acid (HNO 3 ), carbonic acid (H 2 CO 3 ), boric acid (H 3 BO 3 ), seleninic acid (H 2 SeO 3 ), phosphomolybdic acid (H 3 PO 4 .12MoO 3 ), phosphorous acid (H 3 PO 3 ), citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, D-lactic acid, L-lactic acid, DL-lactic acid, oxalic acid, sulphonic acid, benzene sulfonic acid, substituted benzene sulfonic acids, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, propandioic acid, butanedioic acid, fumaric acid, citric acid, orotic acid, benzoic acid, substituted benzoic acids, hydrochloric acid, fumaric acid, nitric acid, hydrobromic acid, sulfuric acid, orotic acid, citric acid, p-toluenesulfonic acid, butanedioic acid, and preferably is hydrochloric acid or fumaric acid; the solvent is a low molecular weight fatty alcohol comprising one of methanol, ethanol, propanol, isopropanol, dichloromethane, chloroform, tetrachloromethane, ethyl ether, petroleum ether and ethyl acetate, or a mixture thereof, and preferably is ethanol.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 88.0
- Lexical Diversity: 1.64706
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15504018', '11404267', '13119692', '15101582', '10530776']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7139794926133198
- 35 USC 102 Novelty (BERT): 0.5082253681212038
- Combined Prediction Score: 0.6934040801641083
- Mean Citation Score: 227.362856
- Max Citation Score: 233.85928
- Similarity Product: 156.0924734362364

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test