PATENT CLAIM ANALYSIS

Application Number: 15779435
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "235800"]

Abstract:
The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R 1  represents a hydrogen atom, an optionally substituted alkyl group, or the like; R 2  represents a hydrogen atom, a halogen atom, or the like; and R 3  represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

Claim (Index 6):
The compound according to  claim 2 , wherein\n Ring A represents (1) a 6 membered monocyclic aryl group optionally substituted with 1 to 2 groups independently selected from the group consisting of a halogen atom and an alkoxy group, or (2) a 5 to 6 membered monocyclic heteroaryl group optionally substituted with 1 to 2 groups independently selected from the group consisting of a halogen atom, wherein said heteroaryl moiety comprises one nitrogen atom and further optionally comprises 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom;\n R 1  represents \n (1) an alkyl group optionally substituted with 1 to 2 groups independently selected from the group consisting of a halogen atom; a hydroxy group; a cyano group; an alkoxy group optionally substituted with a 6 membered monocyclic aryl group; a 6 membered monocyclic aryl group optionally substituted with a group selected from the group consisting of an alkylsulfonyl group and an aminosulfonyl group; a 5 to 6 membered monocyclic heteroaryl group optionally substituted with 1 to 2 groups independently selected from the group consisting of an oxo group and a hydroxy group, wherein said heteroaryl moiety comprises one nitrogen atom and further optionally comprises 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; an optionally partially hydrogenated 10 membered bicyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; a 4 to 7 membered monocyclic aliphatic heterocyclic group optionally substituted with 1 to 2 oxo groups, wherein said aliphatic heterocyclic moiety comprises one nitrogen atom and further optionally comprises one heteroatom independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; an amino group optionally substituted with 1 to 2 groups independently selected from the group consisting of an alkyl group, a 5 to 6 membered monocyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom, an alkoxycarbonyl group, an alkylsulfonyl group, and an aminosulfonyl group; a carbamoyl group optionally substituted with 1 to 2 alkyl groups; and a sulfonyl group optionally substituted with a group independently selected from the group consisting of a 4 to 7 membered monocyclic aliphatic heterocyclic group comprising one nitrogen atom and further optionally comprising one heteroatom independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with a hydroxy group, and an amino group optionally substituted with 1 to 2 alkyl groups, (2) a cycloalkyl group, (3) a 5 to 6 membered monocyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with an alkyl group, (4) a 4 to 7 membered monocyclic aliphatic heterocyclic group comprising one nitrogen atom and further optionally comprising one heteroatom independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with 1 to 2 groups independently selected from the group consisting of an alkyl group optionally substituted with 1 to 2 groups independently selected from the group consisting of a halogen atom, a hydroxy group, and a cyano group, and an alkanoyl group, or (5) an alkanoyl group optionally substituted with an optionally partially hydrogenated 10 membered bicyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom;\n R 2  represents a hydrogen atom, a halogen atom, an alkyl group, a haloalkyl group, or an alkoxy group; \n Ring B represents a 6 membered monocyclic aryl group, a cycloalkyl group, or a 5 to 6 membered monocyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; \n R 4  represents \n (1) an alkyl group, (2) a cycloalkyl group optionally substituted with a carboxyl group, (3) a 5 to 6 membered monocyclic heteroaryl group optionally substituted with a 5 to 6 membered monocyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with an oxo group, wherein said heteroaryl moiety comprises one nitrogen atom and further optionally comprises 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom; (4) a 4 to 7 membered monocyclic aliphatic heterocyclic group comprising one nitrogen atom and further optionally comprising one heteroatom independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with 1 to 2 groups independently selected from the group consisting of a hydroxy group; a halogen atom; an oxo group; a cyano group; an alkyl group; a 5 to 6 membered monocyclic heteroaryl group comprising one nitrogen atom and further optionally comprising 1 to 3 heteroatoms independently selected from the group consisting of a sulfur atom, an oxygen atom, and a nitrogen atom optionally substituted with a group selected from the group consisting of a hydroxy group and an oxo group; a carboxyl group; an alkoxycarbonyl group; a carbamoyl group optionally substituted with 1 to 2 alkyl groups; an alkylsulfonyl group; an alkylsulfonylamino group; an alkylsulfonylaminocarbonyl group; and an aminosulfonylaminocarbonyl group optionally substituted with 1 to 2 alkyl groups; or (5) an amino group optionally substituted with 1 to 2 groups independently selected from the group consisting of an alkyl group optionally substituted with a carboxyl group, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 42.0
- Percentile: 93.0
- Lexical Diversity: 2.03846
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15313407', '15305587', '13154144', '12919973', '14891845']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.722073137398496
- 35 USC 102 Novelty (BERT): 0.5606751930411115
- Combined Prediction Score: 0.7059333429627576
- Mean Citation Score: 313.940092
- Max Citation Score: 427.80472
- Similarity Product: 343.72495013113024

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test