PATENT CLAIM ANALYSIS

Application Number: 15747255
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "094670"]

Abstract:
Engineered anthrax protective antigen (PrAg) proteins are provided wherein the native furin activation site is replaced by the activation site of a membrane-anchored serine protease. These engineered PrAg proteins retain the ability to bind to cell surface PrAg receptors and be proteolytically activated. The proteins also retain the ability to form membrane pores. These engineered PrAg proteins can be used in methods of inducing pore formation in a cell, methods of inducing translocation of a selected compound or co-factor into a cell, and methods of treating disease, such as cancer, in a subject.

Claim (Index 12):
The method of  claim 7 , wherein the selected co-factor is a therapeutic co-factor.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 86.0
- Lexical Diversity: 1.63492
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11055557', '13088011', '12288482', '10088952', '14313575']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8054510961731403
- 35 USC 102 Novelty (BERT): 0.5596118792004041
- Combined Prediction Score: 0.7808671744758667
- Mean Citation Score: 420.404868
- Max Citation Score: 496.04343
- Similarity Product: 307.4292838919073

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test