PATENT CLAIM ANALYSIS

Application Number: 15982038
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "249000"]

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Claim (Index 4):
The compound of  claim 2  having Formula (IV): or a stereoisomer, tautomer, pharmaceutically acceptable salt thereof, wherein:\n R 1a  is selected from the group consisting of: H, halo, C 1-2  alkyl, and methoxy; \n R 1b  is selected from the group consisting of: H and halo; \n R 2  is selected from the group consisting of: H, F, CN, OH, C 1-4  alkoxy, \u2014CHF 2 , \u2014CF 3 , \u2014CH 2 NH 2 , \u2014OCHF 2 , \u2014CO(C 1-4  alkyl), \u2014CONH 2 , \u2014COOH, triazole substituted with R 2a , and tetrazole substituted with R 2a ; \n R 3  is selected from the group consisting of: phenyl substituted with 1-2 R 3a , cyclohexyl substituted with 1-3 R 3a , \n R 3a  is, independently at each occurrence, selected from the group consisting of: \u2550O, F, Cl, C 1-4  alkyl, \u2014OH, \u2014O(C 1-4  alkyl), \u2014CN, \u2014NH 2 , \u2014CO 2 H, \u2014CO 2 (C 1-4  alkyl), \u2014CONHCO 2 (C 1-4  alkyl), \u2014NHCOC 1-4  alkyl, \u2014(CH 2 ) n NHCO 2 (C 1-4  alkyl), and R c ; R 5  is selected from the group consisting of: H, halo, NO 2 , \u2014NH 2 , \u2014NHCOC 1-4  alkyl, \u2014NHCO 2 C 1-4  alkyl, \u2014NHCONH(C 1-4  alkyl), \u2014NR 9 \u2014(CH 2 ) 2 \u2014N(C 1-4  alkyl) 2 , and R 8 ; R 8  is selected from the group consisting of: phenyl and 5- to 10-membered heterocycle containing carbon atoms and 1-4 heteroatoms selected from the group consisting of N, NR a , O, and S; wherein said phenyl or heterocycle is substituted with 0-3 R b ; R a  is H or C 1-4  alkyl; R b  is selected from the group consisting of: \u2550O, halo, C 1-4  alkoxy, and CONH 2 .

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.17949
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15643891', '15183051', '14799681', '14350411', '14350417']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8315324223954136
- 35 USC 102 Novelty (BERT): 0.5069195898750577
- Combined Prediction Score: 0.799071139143378
- Mean Citation Score: 315.033496
- Max Citation Score: 316.3271200000001
- Similarity Product: 312.8566543790771

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test