PATENT CLAIM ANALYSIS

Application Number: 15944193
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["424", "158100"]

Abstract:
The present invention provides a therapeutic composition for prevention or treatment of neurodegenerative brain disease caused by traumatic brain injury, comprising a regulator increasing expression or activity of calcineurin, and a screening method for a therapeutic agent for traumatic brain injury and neurodegenerative brain disease mediated by tau protein.

Claim (Index 7):
A method of screening a therapeutic agent for neurodegenerative brain disease caused by traumatic brain injury comprising:\n treating neural tissue-derived cells with a candidate substance for a therapeutic agent; measuring the expression or activity of calcineurin in the cells; and determining the candidate substance as a therapeutic agent for neurodegenerative brain disease caused by traumatic brain injury, when the expression or activity of calcineurin in the cells treated by the candidate substance are increased more than in untreated cells.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 91.0
- Lexical Diversity: 1.52941
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15503636', '14776924', '14324289', '10625986', '15424444']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6936468123896199
- 35 USC 102 Novelty (BERT): 0.5311755479884349
- Combined Prediction Score: 0.6773996859495014
- Mean Citation Score: 292.59764600000005
- Max Citation Score: 332.16476
- Similarity Product: 217.1401801518631

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test