PATENT CLAIM ANALYSIS

Application Number: 15753291
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["564", "152000"]

Abstract:
Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.

Claim (Index 3):
The salt of  claim 1  wherein the cationic protonated polyamine pharmaceutical agent is a protonated form of a polyamine of formula (I) and the anionic hydrophobic carboxylate is a carboxylate form of a fatty acid selected from decanoic acid and dodecanoic acid, wherein\n a, b, and c independently range from 1 to 10; \n d and e independently range from 0 to 30; \n each X is independently either a carbon (C) or sulfur (S) atom; \n R 1  and R 2  are independently selected from H or from the group of\n a straight or branched C 1-50  saturated or unsaturated aliphatic, carboxyalkyl, carbalkoxyalkyl, or alkoxy; \n a C 1-8  alicyclic; \n a single or multiring aryl substituted or unsubstituted aliphatic; \n an aliphatic-substituted or unsubstituted single or multiring aromatic; \n a single or multiring heterocyclic; \n a single or multiring heterocyclic aliphatic; \n a C 1-10  alkyl; \n an aryl sulfonyl; \n or cyano; or \n R 2 X(O) n \u2014 is replaced by H; \n \n wherein * denotes a chiral carbon position; and wherein if X is C then n is 1; if X is S then n is 2; and if X is C then the XO group may be CH 2  such that n is 0.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 88.0
- Lexical Diversity: 1.31915
- Patent Class: 564.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['09713512', '09396523', '12294462', '11062481', '15353213']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7163496868269529
- 35 USC 102 Novelty (BERT): 0.520809074448641
- Combined Prediction Score: 0.6967956255891217
- Mean Citation Score: 214.154076
- Max Citation Score: 219.97829
- Similarity Product: 144.14545824146984

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test