PATENT CLAIM ANALYSIS

Application Number: 15925656
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["382", "128000"]

Abstract:
Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Claim (Index 25):
A system for determining the identity of a plurality of analytes, comprising\n a. an optical imaging device configured to image a plurality of optical signals from a field of a substrate over a plurality of cycles of probe binding to analytes immobilized on a surface of the substrate; and b. an image processing module, said module configured to:\n i. determine a peak location from each of said plurality of optical signals from images of said field from at least two of said plurality of cycles; \n ii. determine a relative position of each detected analyte on said surface with improved accuracy by applying an optical distribution model to each cluster of optical signals from said plurality of cycles; and \n iii. deconvolve said optical signals in each field image from each cycle using said determined relative position and a deconvolution function.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 90.0
- Lexical Diversity: 1.2973
- Patent Class: 382.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14366486', '12009659', '13835492', '14922038', '15207892']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2680187568271314
- 35 USC 102 Novelty (BERT): 0.497242897079271
- Combined Prediction Score: 0.2909411708523454
- Mean Citation Score: 183.510428
- Max Citation Score: 219.60469
- Similarity Product: 156.87759143114567

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test