PATENT CLAIM ANALYSIS

Application Number: 15759119
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["564", "057000"]

Abstract:
Provided are a cyclohexane derivative as shown by formula IB or a stereoisomer or a salt thereof, and the preparation and use thereof. The cyclohexane derivative has a high affinity for D 3  receptors and 5-hydroxytryptamine, has a lower affinity for D 2  receptors, shows a high selectivity for D 3 /D 2  receptors, and can be used as a therapeutic drug against neuropsychiatric diseases; and the preparation method thereof is simple and easy.

Claim (Index 12):
The method according to  claim 9 , wherein the pharmaceutical composition is a suspension consisting of the cyclohexane derivative of formula IB or formula I or stereoisomer or salt thereof as an active ingredient and pharmaceutical excipients; and the suspension consists of the following components based on weight:\n active ingredient: 1-40 mg; diluent: 10-200 mg; suspending agent: 0.1-10 mg; preservative: 0.01-0.5 mg; buffer: 4-8 mg; co-solvent: 0-50 mg; flavoring agent: 0-1 mg; and colorant: 0-0.1 mg; wherein the suspending agent is selected from xanthan gum or microcrystalline cellulose; the preservative is selected from sodium benzoate, methyl or ethyl p-hydroxybenzoate; the diluent is selected from water or sorbitol; the buffer is citrate; the co-solvent is selected from cyclodextrin, ethanol, propylene glycol or polyethylene glycol; the flavoring agent is a sweetener selected from sugar or saccharin; the colorant is a fat-soluble or water-soluble colorant selected from carotene, cocoa pigment or caramel pigment.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 90.0
- Lexical Diversity: 1.7234
- Patent Class: 564.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14889831', '15124264', '15029218', '13123368', '13056365']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7271685689171633
- 35 USC 102 Novelty (BERT): 0.5346228669649938
- Combined Prediction Score: 0.7079139987219463
- Mean Citation Score: 248.190766
- Max Citation Score: 269.30753
- Similarity Product: 182.2782871443069

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test