PATENT CLAIM ANALYSIS

Application Number: 15754193
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "313000"]

Abstract:
The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8  are defined herein.

Claim (Index 37):
A method for modulating activity of a human toll-like receptor, comprising administering to a subject in need thereof, a compound of formula (III): or a salt thereof, wherein:\n R 11 , R 12 , R 13 , R 14 , and R 15  are independently selected from the group consisting of: H, halogen, \u2014OR 20 , \u2014N(R 20 ) 2 , \u2014SR 20 , \u2014CN, \u2014NO 2 , \u2014OC(O)R 20 , \u2014C(O)R 20 , \u2014C(O)OR 20 , \u2014C(O)NR 20 , \u2014S(O) 2 R 20 , \u2014S(O) 2 OR 20 , optionally substituted C 3-20  carbocycle, optionally substituted C 1-20  alkyl, optionally substituted C 2-20  alkenyl, optionally substituted C 2-20  alkynyl, and optionally substituted 3- to 20-membered heterocycle, \n wherein at least one of R 1 , R 12 , R 13 , and R 14  is selected from the group consisting of \u2014OR 20 , \u2014NR 20 2 , \u2014OC(O)R 20 , \u2014C(O)R 20 , \u2014C(O)OR 20 , \u2014C(O)NR 20 , \u2014S(O) 2 R 20 , \u2014S(O) 2 OR 20 , optionally substituted C 3-20  carbocycle, optionally substituted C 1-20  alkyl, optionally substituted C 2-20  alkenyl, optionally substituted C 2-20  alkynyl, and optionally substituted 3- to 20-membered heterocycle; \n R 16  is optionally substituted C 1-20  alkyl, \u2014OR 21 , \u2014N(R 21 ) 2 , \u2014SR 21 , optionally substituted C 2-20  alkenyl, and optionally substituted C 2-20  alkynyl; \n R 17  and R 18  are independently selected from H, optionally substituted C 1-10  alkyl, optionally substituted C 2-10  alkenyl, optionally substituted C 2-10  alkynyl, optionally substituted C 3-12  carbocycle and optionally substituted 3- to 12-membered heterocycle; \n R 20  is independently selected at each occurrence from the group consisting of H, optionally substituted C 1-10  alkyl, optionally substituted C 2-10  alkenyl, optionally substituted C 2-10  alkynyl, optionally substituted 3- to 12-membered heterocycle and optionally substituted C 3-12  carbocycle; and \n R 21  is independently selected at each occurrence from the group consisting of optionally substituted C 1-10  alkyl, optionally substituted C 2-10  alkenyl, and optionally substituted C 2-10  alkynyl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15509989', '15691408', '10493279', '11516831', '15829604']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8006538348046196
- 35 USC 102 Novelty (BERT): 0.5352443920181752
- Combined Prediction Score: 0.7741128905259751
- Mean Citation Score: 358.38470199999995
- Max Citation Score: 380.84268
- Similarity Product: 258.81682647452834

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test