PATENT CLAIM ANALYSIS

Application Number: 16068670
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["435", "006130"]

Abstract:
Practical assays to identify compounds that overcome the resistance of  M. tuberculosis  to bedaquiline are based on transcription factors Rv0324 and Rv0880 shown to mediate this resistance.

Claim (Index 1):
A method to identify a compound that potentiates the treatment of tuberculosis (TB) by bedaquiline (BDQ) which method comprises assessing the ability of a test compound to diminish the activity of transcription factor Rv0880 or transcription factor Rv0324 wherein a compound that diminishes the activity of one or both of said transcription factors is identified as a compound that potentiates the treatment of tuberculosis with BDQ.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 95.0
- Lexical Diversity: 1.12
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['09949041', '10481563', '13000788', '15381901', '14527281']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.542985246613303
- 35 USC 102 Novelty (BERT): 0.4952921086011325
- Combined Prediction Score: 0.538215932812086
- Mean Citation Score: 152.33914
- Max Citation Score: 159.17937
- Similarity Product: 100.65504861109436

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test