PATENT CLAIM ANALYSIS

Application Number: 15894107
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "377000"]

Abstract:
This invention relates, e.g., to a method for differentiating mammalian (e.g., human) pluripotent stem cells (PSCs) into endothelial cells (ECs) in vitro, by plating a single-cell suspension of PSCs onto a suitable surface such as type IV collagen and culturing the cells with VEGF after which ECs can be harvested. A preferred embodiment of the method first cultures the cells without VEGF and then sequentially cultures the cells with VEGF. Differentiation can be enhanced by adding an inhibitor of transforming growth factor β to the culturing with VEGF.

Claim (Index 2):
The method for differentiating PSCs of  claim 1  wherein the VEGF ranges from 1 to 50 ng/ml.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.57812
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14777258', '13844313', '13581341', '14897619', '15637068']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5655999759178441
- 35 USC 102 Novelty (BERT): 0.5304115910774101
- Combined Prediction Score: 0.5620811374338006
- Mean Citation Score: 296.55038
- Max Citation Score: 350.06534
- Similarity Product: 333.09735288310407

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test