PATENT CLAIM ANALYSIS

Application Number: 15778457
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "185000"]

Abstract:
The one subject of the invention is the compounds of general formula (I), their isomers, their physiologically acceptable salts and/or Mn(II), Fe(II), Fe(III), Co(II) and Ni(II) complexes. The other subject of the invention is the application of the above compounds. The compounds of general formula (I): wherein R a  refers to —OH group or —NR 3 R 4  group and —NR 3 R 4  group may refer to: a) —NR 3 R 4  with N atom in the ring means a ring of 4 to 7, that in certain cases may contain another heteroatom, and in specific cases the ring may be replaced with an aryl group (of 5 to 7 carbon atoms) substituted with —COOH, —OH, —OCH 3 , —NO 2 , —NH 2 , —NCS, —NHS— activated ester, aryl (of 5 to 7 carbon atoms), or nitro-, amino- or isothiocyanate group, or b) in the —NR 3 R 4  group R 3  means a H atom, alkyl, aryl, nitroaryl, aminoaryl or isothiocyanate-aryl group (of 1 to 6 carbon atoms) and R4 is a H atom, alkyl (of 1 to 6 carbon atoms) or —(CH 2 ) n —COOH group, whereas n=1 to 10 integer, or c) —NR 3 R 4  group is one of the below groups: whereas R 1  is a H atom, carboxyl or alkyl-carbonyl group (of 1 to 4 carbon atoms); and R b  is a H atom or alkyl group (of 1 to 6 carbon atoms), and X means independently from one another H atom, —CH 3 , —COOH, —OH, —OCH 3 , alkoxy- (of 2 to 6 carbon atoms), —NO2, —NH2, —NCS, —NHS-activated ester, alkyl (of 2 to 12 carbon atoms) or aryl (of 5 to 7 carbon atoms) group, in certain cases the latter may be substituted with hydroxyl, hydroxyalkyl (of 1 to 6 carbon atoms), nitro, amino or isothiocyanate group; and Y means: —NH— or >NCH 2 —Z group, whereas in the >CH 2 —Z group Z refers to one selected group of the below: —C(O)NR 3 R 4  group, in which —NR 3 R4 means as referred to above, whereas z=0-18 integer, whereas z=0-18 integer, whereas z=0-18 integer, whereas z=0-18 integer and H atom, alkyl (of 1 to 6 carbon atoms) or —(CH 2 ) n —COOH group, whereas n=1 to 10 integer, or, whereas z=0-18 integer, whereas z=0-18 integer and R 2a  refers to H atom, —OCH 3 , or —CF 3  group, whereas R 2b  refers to H atom, —CH 3 , —OCH 3 >.CF 3 ; —COOH, —COON(CO) 2 (CH 2 ) 2 , —NO 2 , —NH 2  or —NCS— group, whereas z=0-18 integer and R 2 c refers to H atom, NO 2 , —NH 2  or —NCS— group, whereas ζ=0-18, -and x=1-5 integer, whereas z=0-18. and x=1.5 integer; whereas z=1-5, and x=1-5 integer, R 2d  refers to H atom, —CH 3 , —OCH 3 ;.CF 3 , —COOH, —COON(CO) 2 (CH 2 ) 2 , —NO 2 , —NH 2  or —NCS group,

Claim (Index 5):
A kit for use in MRI or  52 Mn-based PET diagnostic imaging, comprising:\n a compound of  claim 1 , an isomer thereof, a physiologically acceptable salt thereof, and/or a Mn(II), Fe(II), Fe(III), Co(II), or Ni(II) complex thereof.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 93.0
- Lexical Diversity: 4.40278
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15778506', '11630605', '10499887', '14003514', '09869777']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7829318250822581
- 35 USC 102 Novelty (BERT): 0.5710669351439623
- Combined Prediction Score: 0.7617453360884285
- Mean Citation Score: 352.53757000000013
- Max Citation Score: 513.05084
- Similarity Product: 355.7790059567642

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test