PATENT CLAIM ANALYSIS

Application Number: 15957686
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "001000"]

Abstract:
Disclosed herein are embodiments of a method for using estrogenic compounds to manipulate the bacterial composition of vaginal communities of female subjects. The method may include titrating a dose of an estrogenic compound to provide a female subject with a personalized effective dose, such as a minimum effective dose, sufficient to attain and/or maintain one or more determined target values of a relative abundance of vaginal  Lactobacillus  in the vaginal microbiota, an absolute abundance of vaginal  Lactobacillus  in the vaginal microbiota, a vaginal pH, a vaginal lactic acid concentration, or any combination thereof.

Claim (Index 10):
The method of  claim 1 , where obtaining analysis results of the vaginal sample comprises using a diagnostic test comprising using quantitative PCR, universal bacterial primers, and genus-specific  Lactobacillus  primers to determine the relative abundance of  Lactobacillus  based on a ratio of  Lactobacillus  16S rRNA gene copies to total bacterial 16S rRNA gene copies in the vaginal microbiota.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.68333
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15536297', '11331856', '15155675', '15740807', '14496737']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7152584167027591
- 35 USC 102 Novelty (BERT): 0.5080818923663185
- Combined Prediction Score: 0.6945407642691152
- Mean Citation Score: 232.489466
- Max Citation Score: 243.5908
- Similarity Product: 168.13173522729875

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test