PATENT CLAIM ANALYSIS

Application Number: 16250733
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-07
Patent Classification: ["424", "009300"]

Abstract:
The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.

Claim (Index 59):
A method of diagnosing or monitoring the progression of a neurodegenerative tauopathy in a subject, comprising:\n (a) providing a biological sample from a patient to be diagnosed and contacting the biological sample with an antibody, or fragment thereof, of  claim 49 ; (b) measuring the level of pathologically modified or aggregated tau protein in a biological sample from the subject to be diagnosed with the antibody, or fragment thereof, of  claim 49  by immunochemistry; and, (c) comparing the level of modified or aggregated tau protein to a reference standard that indicates the level of the pathologically modified or aggregated tau in one or more control subjects, wherein a difference or similarity between the level of pathologically modified or aggregated tau and the reference standard indicates that the subject has a neurodegenerative tauopathy.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 99.0
- Lexical Diversity: 1.45098
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15552633', '15552614', '15528333', '15342629', '14154954']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6790569571730285
- 35 USC 102 Novelty (BERT): 0.6696783055983356
- Combined Prediction Score: 0.6781190920155592
- Mean Citation Score: 442.0793660000001
- Max Citation Score: 674.6227
- Similarity Product: 628.6744768968582

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test