PATENT CLAIM ANALYSIS

Application Number: 15958192
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "318000"]

Abstract:
One aspect of the invention relates to a series of new PCSK9 inhibitor compounds comprising piperidine ring structures, including compounds of formula (I) and/or pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating PCSK9 receptor related diseases comprising administration of one or more compounds of formula (I) or a pharmaceutically acceptable salt thereof.

Claim (Index 1):
A compound of formula (I), and/or a pharmaceutically acceptable salt thereof, Wherein, T 1  is chosen from N and CH; T 2  is chosen from CH and N; T 3  is chosen from CH and N; D is chosen from N is chosen from 0, 1, 2 and 3; Each R 1  is independently chosen from halogen, OH and NH 2 , or chosen from a C 1-3  alkyl, C 1-3  heteroalkyl, C 3-6  cycloalkyl, phenyl, and 5 or 6 membered heteroaryl group, any of which is optionally substituted by one, two or three R groups; or, two adjacent R 1  are connected together to form a 5 or 6 membered ring which is optionally substituted by one, two or three R groups; R 3  is chosen from H, halogen, OH and NH 2 , or chosen from a C 1-3  alkyl group that is optionally substituted by one, two or three R groups; Each R 4  is independently chosen from H and OH, or chosen from a C 1-3  alkyl group and a C 1-3  alkoxy group, either of which is optionally substituted by one, two or three R groups; R is chosen from F, Cl, Br, I, OH, NH, NH(CH 3 ), N(CH 3 ) 2 , Me and wherein each of said C 1-3  heteroalkyl and 5 or 6 membered heteroaryl independently comprises 1, 2, or 3 heteroatom groups independently chosen from \u2014NH\u2014, N, \u2014O\u2014, and \u2014S\u2014.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 91.0
- Lexical Diversity: 1.625
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16317510', '15562825', '16087861', '16326976', '15502356']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7580143901631843
- 35 USC 102 Novelty (BERT): 0.5042987314554823
- Combined Prediction Score: 0.7326428242924141
- Mean Citation Score: 261.95721799999995
- Max Citation Score: 276.37018
- Similarity Product: 244.8854869541776

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test