PATENT CLAIM ANALYSIS

Application Number: 16283640
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["514", "343000"]

Abstract:
The invention provides novel compounds having the general formula (I) wherein R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , X, A and R 11  are as described herein, compositions including the compounds and methods of using the compounds.

Claim (Index 2):
The compound of  claim 1 , or a pharmaceutically acceptable salt thereof, wherein\n R 2  is C 1-6 -alkyl; R 3 , R 4 , R 5  and R 7  are H; X is selected from\n i) \u2014O\u2014, \n ii) \u2014S\u2014, and \n iii) \u2014S(O) 2 \u2014; \n R 6  is phenyl-C 1-6 -alkyl substituted with R 12 , R 13  and R 14 ; A is selected from\n i) \u2014O\u2014, \n ii) \u2014CH 2 \u2014, \n iii) \u2014S(O) 2 NR 10 \u2014 and \n iv) \u2014C(O)NR 10 \u2014; \n R 8  is selected from\n i) H, and \n ii) \u2014CH 2 R 9 ; \n R 9  is selected from\n i) H, and \n ii) hydroxy, \n iii) C 1-6 -alkoxy, \n iv) phenyl substituted with R 15 , R 16  and R 17 , and \n v) C 1-6 -alkylsilyloxy; \n R 11  is selected from\n i) phenyl substituted with R 18 , R 19  and R 20 , \n ii) phenyl-C 3-8 -cycloalkyl substituted with R 18 , R 19  and R 20 , \n iii) phenyl(halo)-C 1-6 -alkyl substituted with R 18 , R 19  and R 20 , and \n iv) heteroaryl substituted with R 18 , R 19  and R 20 , wherein heteroaryl is selected from\n a. pyrazinyl, \n b. pyridinyl, and \n c. thiophenyl; \n \n R 12  is selected from\n i) H, and \n ii) C 1-6 -alkoxy, \n R 15  is selected from\n i) H, \n ii) halogen, and \n iii) amino-C 1-6 -alkyl substituted on the nitrogen atom by one H and one C 1-6 -alkoxycarbonyl; \n R 18  is selected from\n i) H, \n ii) halogen, and \n iii) halo-C 1-6 -alkyl; \n and R 13 , R 14 , R 16 , R 17 , R 19  and R 20  are H; with the proviso that N-[(1S)-1-[[(1S)-1-[(2S,4R)-4-benzyloxy-2-[(1-ethyl-3,3,3-trifluoro-2-oxo-propyl)carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-2-methyl-propyl]pyrazine-2-carboxamide is excluded.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 99.0
- Lexical Diversity: 1.55556
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15683341', '11703522', '12829526', '12338432', '15031493']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8001911658441442
- 35 USC 102 Novelty (BERT): 0.5578568372593238
- Combined Prediction Score: 0.7759577329856622
- Mean Citation Score: 373.851888
- Max Citation Score: 427.60535
- Similarity Product: 311.738204370594

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test