PATENT CLAIM ANALYSIS

Application Number: 16225213
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-07
Patent Classification: ["250", "282000"]

Abstract:
The invention relates to a method, a device and a system for the treatment of biological frozen samples using plasma focused ion beams (FIB). The samples can then be used for mass spectrometry (MS), genomics, such as gene sequencing analysis or next generation sequencing (NGS) analysis, and proteomics. The present invention particularly relates to a method of treatment of at least one biological sample. This method is particularly used for high performance microscopy, proteomics analytics, sequencing, such as NGS etc. According to the present invention the method comprises the steps of providing at least one biological sample in frozen form. The milling treats at least one part of the sample by a plasma ion beam comprising at least one of an O +  and/or a Xe +  plasma.

Claim (Index 8):
Method according to any of the preceding claims with the further step of analyzing the sample or the accumulated sample, in particular proteins in the sample, by mass spectrometry, preferably by an orbitrap fusion mass spectrometer.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 98.0
- Lexical Diversity: 1.98649
- Patent Class: 250.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11119207', '14642138', '13609811', '15883025', '14963654']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7172599833722272
- 35 USC 102 Novelty (BERT): 0.4895337729653216
- Combined Prediction Score: 0.6944873623315366
- Mean Citation Score: 169.50365000000005
- Max Citation Score: 172.34581
- Similarity Product: 109.70679885808468

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test