PATENT CLAIM ANALYSIS

Application Number: 15996945
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["514", "338000"]

Abstract:
The present invention provides a compound of formula I; wherein R 1  is an alkyl pyrazole or an alkyl carboxamide, and R 2  is a hydroxycycloalkyl; or a pharmaceutically acceptable salt thereof,and compositions containing these compounds, for use to treat a brain tumor, particularly glioblastoma. The invention provides effective treatment of a brain tumor and can be used by oral administration of a compound of Formula I as further described herein. The invention also provides a method to treat a subject having a brain tumor such as glioblastoma, wherein the method comprises administering to the subject an effective amount of a compound of Formula I. Gene signatures correlated with successful treatment using these methods are also disclosed.

Claim (Index 2):
The method of  claim 1 , wherein the compound is a pharmaceutically acceptable salt.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 94.0
- Lexical Diversity: 1.77778
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15533842', '15293055', '14615416', '14128882', '14409668']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7398135231558666
- 35 USC 102 Novelty (BERT): 0.5227082407061104
- Combined Prediction Score: 0.7181029949108909
- Mean Citation Score: 252.98109400000004
- Max Citation Score: 274.5198
- Similarity Product: 175.1546312458992

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test