PATENT CLAIM ANALYSIS

Application Number: 15746338
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["544", "037000"]

Abstract:
The present invention pertains generally to the field of chemical synthesis, and more particularly to methods of chemical synthesis which include the step of preparing a substituted 10H-phenothiazine-3,7-diamine compound of Formula (1) by a step of selective alkylation by reductive amination, in which the corresponding unsubstituted diamine of Formula (4) is reacted with aldehyde/ketone, under reductive amination conditions. The present invention also relates to such methods which incorporate additional subsequent and/or preceding steps, for example, to prepare compounds of Formulae (2) and (3) from compounds of Formula (1), and to prepare compounds of Formula (4) from, for example, compounds of Formulae (5), (6), (7), (8), and (9). Compounds of Formula (1), Formula (2), and Formula (3) are useful, for example, in the treatment of diseases of protein aggregation, such as Alzheimer's disease.

Claim (Index 80):
A method according to  claim 72 , wherein:\n R 3  is H; R 4  is H; R 5  is H; R 6  is H; R 7  is H; and R 8  is H.

Metadata:
- Claim Count in Document: 68.0
- Percentile: 86.0
- Lexical Diversity: 2.32051
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14410952', '13063525', '13984841', '15056610', '13241887']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7269002842337061
- 35 USC 102 Novelty (BERT): 0.5177001266909922
- Combined Prediction Score: 0.7059802684794347
- Mean Citation Score: 219.46046
- Max Citation Score: 265.7381
- Similarity Product: 168.05463715820906

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test