PATENT CLAIM ANALYSIS

Application Number: 15871187
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["514", "291000"]

Abstract:
The invention relates generally to neuroprotection and repair in neurological disorders involving Tau dysfunction (including Alzheimer's disease). The invention describes AND INCLUDES a direct interaction between proteins FKBP52 and Tau. More particularly, the invention relates to a method for screening a drug for the prevention and treatment of neurological disorders involving Tau dysfunction comprising the following steps: a) determining the ability of a candidate compound, to modulate the interaction between a Tau polypeptide and a FKBP52 polypeptide and b) selecting positively the candidate compound that modulates said interaction. The present invention finally relates to diagnostic, prognostic, and monitoring assays of neurological disorders involving Tau dysfunction.

Claim (Index 11):
A method of treating neurological disorders involving Tau dysfunction, in a subject thought to have or be predisposed to having a neurological disorder involving Tau dysfunction, comprising the administration to said subject of an effective amount of a compound which enhances the interaction between Tau and FKBP52 proteins, so as to prevent aggregation of Tau protein.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.88889
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13497907', '14814674', '14132832', '14324289', '13393220']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8035095946072632
- 35 USC 102 Novelty (BERT): 0.6186417679345549
- Combined Prediction Score: 0.7850228119399923
- Mean Citation Score: 471.54599
- Max Citation Score: 611.5473599999998
- Similarity Product: 505.38506014924025

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test