PATENT CLAIM ANALYSIS

Application Number: 16184270
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["424", "139100"]

Abstract:
Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are usefule in the treatment of diseases associated with increased production of IFNα and IFNω.

Claim (Index 1):
An isolated monoclonal antibody that binds human interferon omega (IFN\u03c9) at least at residues R22, R23, I24, S25, P26, F27, L30, K31, D32, R33, R34, D35, Q40, K134, M146, E147, M149, K150, F153 and L154 of SEQ ID NO: 1, and at least one IFN\u03b14a residue selected from the group consisting of A19, G22, R23, I24, S25, H26, F27, C29, L30, K31, D32, R33, H34, D35, V143, A146, E147, M149, R150 and S153 of SEQ ID NO: 19, wherein the antibody neutralizes an activity of IFN\u03b1A, IFN\u03b1H2, IFN\u03b1K, IFN\u03b1WA, IFN\u03b14a, IFN\u03c9, IFN\u03b1B2, IFN\u03b1C, IFN\u03b1F, IFN\u03b1G and IFN\u03b1J1 and the antibody does not bind or neutralize human IFN\u03b1D.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 98.0
- Lexical Diversity: 1.25806
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14208861', '15707317', '14745939', '12551250', '14902409']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7404993843550626
- 35 USC 102 Novelty (BERT): 0.5482339765195627
- Combined Prediction Score: 0.7212728435715127
- Mean Citation Score: 300.085278
- Max Citation Score: 397.9143
- Similarity Product: 305.35972890415195

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test