PATENT CLAIM ANALYSIS

Application Number: 16065393
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "001650"]

Abstract:
The present invention is directed to novel non-invasive diagnostic took to dispose numerous disease states and/or conditions. The presets invention, represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these disease states. The novel imaging probe is capable of detecting infected cells, as well tissue. The methods described herein are able to diagnose, treat and/or monitor the therapy of numerous diseases and conditions including atherosclerosis, atherothrombosis, cerebral vascular disease, cerebral ischemia, cerebral infarct and meningitis as well as pneumonitis, pericarditis, multiple sclerosis, lupus erythematosus and pancreatitis, among others.

Claim (Index 22):
A method of monitoring the treatment of a ICAM-1/LFA-1 mediated disease or condition in tissue of a patient comprising administering to said patient undergoing a course of treatment for said disease or condition an effective amount of at least one compound according to the chemical structure: Where Y is a chemical linker which links the nitrogen to a chelate group or tricarbonyl complex X, wherein X incorporates or complexes with a radioisotope, or a pharmaceutically acceptable salt thereof; measuring the amount of said compound which binds to said tissue in said patient at two different times or more during treatment; and comparing the measurements obtained in said measuring step at said different times with a standard from normal tissue and/or tissue impacted by said disease state and/or condition, wherein said measurements obtained from said patient are compared to said standard(s) and optionally, to each other, such that said comparison is indicative of the progress or absence of progress in the treatment of said disease or condition wherein said disease or condition is atherosclerosis, the extent and/or buildup of atherosclerotic plaque, atherothrombosis, cerebral vascular disease, cerebral ischemia, cerebral infarct, meningitis, pneumonitis, pericarditis, multiple sclerosis, lupus erythematosus or pancreatitis.

Metadata:
- Claim Count in Document: 51.0
- Percentile: 94.0
- Lexical Diversity: 1.52778
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13447918', '15261890', '12991253', '14093260', '13643412']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7204301482776446
- 35 USC 102 Novelty (BERT): 0.4739645537400798
- Combined Prediction Score: 0.6957835888238881
- Mean Citation Score: 244.28381200000004
- Max Citation Score: 247.1997
- Similarity Product: 240.83270628880263

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test