PATENT CLAIM ANALYSIS

Application Number: 16439620
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-09
Patent Classification: ["210", "645000"]

Abstract:
A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

Claim (Index 53):
A method for delivering a small molecule chemotherapeutic agent to a selected organ, or section of an organ, of a mammalian subject while restricting systemic exposure of the mammalian subject to the small molecule chemotherapeutic agent, comprising:\n placing one or more catheters within venous vasculature which drains the organ, or section of an organ, at least one of the catheters having two or more expandable members; isolating the organ, or section of the organ, by occluding flow of blood within the venous vasculature which drains the organ, or section of the organ, by inflating the expandable members; delivering the chemotherapeutic agent to the isolated organ or isolated section of the organ; perfusing the chemotherapeutic agent to perfuse within the isolated organ, or section of an organ, for a period of time sufficient to provide a therapeutic effect; removing blood from the isolated organ, the blood comprising the small molecule chemotherapeutic agent; filtering the blood to remove the small molecule chemotherapeutic agent by passing the blood through a filter apparatus comprising a housing having an inlet and an outlet, an extraction media comprising hemocompatible polymer coated carbon cores contained within the housing, wherein the carbon cores have a pore volume of about 1.68 cc/g to about 2.17 cc/g.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 100.0
- Lexical Diversity: 1.71698
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16127008', '13671549', '15651141', '14013005', '12815453']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7734404276028536
- 35 USC 102 Novelty (BERT): 0.5605055512305981
- Combined Prediction Score: 0.752146939965628
- Mean Citation Score: 335.753452
- Max Citation Score: 448.582
- Similarity Product: 343.1317481443882

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test