PATENT CLAIM ANALYSIS

Application Number: 16018247
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "072000"]

Abstract:
The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.

Claim (Index 5):
The engineered transaminase polypeptide of  claim 4 , wherein the transaminase polypeptide sequence further comprises at least one substitution selected from:\n X45 is H, X86 is Y, X211 is K, X294 is V, X324 is G; X391 is A, X398 is R, and X420 is N; X9 is T, X45 is H, X86 is Y, X177 is L, X211 is K, X294 is V, X324 is G, and X391 is A; X21 is N, X45 is H, X177 is L, X208 is I, X211 is K, X324 is G, and X391 is A; and X9 is T, X21 is N, X86 is Y, X208 is I, and X294 is V.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.47368
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14684916', '15912892', '15341631', '13920902', '13381155']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7822899007526485
- 35 USC 102 Novelty (BERT): 0.7557659917639454
- Combined Prediction Score: 0.7796375098537782
- Mean Citation Score: 789.1678159999999
- Max Citation Score: 898.8333
- Similarity Product: 861.9701441841423

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test