PATENT CLAIM ANALYSIS

Application Number: 16192274
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "004400"]

Abstract:
The present disclosure relates to polynucleotides comprising an open reading frame of linked nucleosides encoding human interleukin-12 (IL12), functional fragments thereof, and fusion proteins comprising IL12. In some embodiments, the open reading frame is sequence-optimized. In particular embodiments, the disclosure provides sequence-optimized polynucleotides comprising nucleotides encoding the polypeptide sequence of human IL12, or sequences having high sequence identity with those sequence optimized polynucleotides.

Claim (Index 163):
The method of  claim 162 , wherein the anti-tumor response comprises inducing IFN\u03b3 production.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 98.0
- Lexical Diversity: 1.55319
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15996146', '15995889', '16184282', '16002376', '16002472']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8697500656387661
- 35 USC 102 Novelty (BERT): 0.6219741761966885
- Combined Prediction Score: 0.8449724766945583
- Mean Citation Score: 642.8568
- Max Citation Score: 880.4875
- Similarity Product: 497.2517082810402

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test