PATENT CLAIM ANALYSIS

Application Number: 15922980
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "262100"]

Abstract:
To provide a novel compound having a HER2 inhibitory effect and having a cytostatic effect. It is also intended to provide a medicament useful in the prevention and/or treatment of a disease involving HER2, particularly, cancer, on the basis of the HER2 inhibitory effect. The present invention provides a compound of formula (I) wherein X, Y, Z 1 , Z 2 , Z 3 , Z 4 , W, n, R 1 , R 2 , and R 3  have meanings as defined in the present specification, or a salt thereof.

Claim (Index 27):
The method according to  claim 18 , wherein in the formula (I),\n X is a 4- to 8-membered nitrogen-containing saturated heterocyclic group optionally having a halogen atom or a C1-C6 alkyl group as a substituent; Y is \u2014C(R 4 )\u2550C(R 5 )(R 6 ); Z 1 , Z 2 , Z 3 , and Z 4  are the same as or different from each other and each are a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, an optionally halogen atom-substituted C1-C6 alkoxy group, a C1-C6 alkyl group, an optionally C1-C6 alkyl group-substituted amino group, a C3-C7 cycloalkyl group, or a monocyclic 4- to 6-membered unsaturated heterocyclic group having one oxygen atom, or Z 1  and Z 2 , or Z and Z 4  optionally form, together with the respective carbon atoms bonded thereto, a benzene ring or a 5- to 7-membered saturated or unsaturated heterocyclic ring; W is an oxygen atom, or \u2014NH\u2014; n is 0; R 1  is an amino group; R 2  and R 3  are the same as or different from each other and each are a hydrogen atom, a C1-C6 alkoxy group, a C1-C6 alkyl group, or a C6-C14 aromatic hydrocarbon group, or R 2  and R 3  optionally form, together with the nitrogen atom bonded thereto, an optionally hydroxyl group-substituted 4- to 8-membered nitrogen-containing saturated heterocyclic group; and R 4 , R 5 , and R 6  are the same as or different from each other and each are a hydrogen atom or an optionally di(C1-C6 alkyl)amino group-substituted C1-C6 alkyl group.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 90.0
- Lexical Diversity: 1.76271
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15297196', '14784239', '14710631', '15861947', '12738885']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7853415039107569
- 35 USC 102 Novelty (BERT): 0.5451435077380414
- Combined Prediction Score: 0.7613217042934853
- Mean Citation Score: 354.839194
- Max Citation Score: 379.9677
- Similarity Product: 292.3320651361227

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test