PATENT CLAIM ANALYSIS

Application Number: 16098138
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["548", "408000"]

Abstract:
The present invention relates to novel methods for preparing cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives and also to novel intermediates and starting compounds, which are passed through or used in the method according to the invention.

Claim (Index 1):
Method for preparing a compound of formula (I) in which X is C 1 -C 6 -alkyl, halogen, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkyl or C 1 -C 6 -haloalkoxy, Y is hydrogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, halogen, C 1 -C 6 -haloalkyl or C 1 -C 6 -haloalkoxy, wherein only one of the radicals X or Y may be C 1 -C 6 -haloalkyl or C 1 -C 6 -haloalkoxy, A is C 1 -C 6 -alkyl, G is the group in which R\u2032 is C 1 -C 20 -alkyl, C 2 -C 20 -alkenyl, C 1 -C 8 -alkoxy-C 2 -C 8 -alkyl or poly-C 1 -C 8 -alkoxy-C 2 -C 8 -alkyl, in each case optionally substituted by halogen,\n is C 3 -C 8 -cycloalkyl optionally substituted by halogen, C 1 -C 6 -alkyl or C 1 -C 6 -alkoxy or \n is phenyl or benzyl in each case optionally substituted by halogen, cyano, nitro, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkyl or C 1 -C 6 -haloalkoxy, \n wherein firstly a compound of formula (II) in which X, Y and A are as defined above and R\u2033 is C 1 -C 6 -alkyl, are cyclized in the presence of a base and in the presence of one or more solvents to give compound of formula (III) in which X, Y and A are as defined above and M is an alkali metal ion, an ion equivalent of an alkaline earth metal, an ion equivalent of aluminium or an ion equivalent of a transition metal, or further\n is an ammonium ion, in which optionally one, two, three or all four hydrogen atoms can be replaced by identical or different radicals from the groups C 1 -C 5 -alkyl, C 1 -C 5 -isoalkyl or C 3 -C 7 -cycloalkyl, which can in each case be substituted one or more times with fluorine, chlorine, bromine, cyano, hydroxy or be interrupted by one or more oxygen or sulphur atoms, or further \n is a cyclic secondary or tertiary aliphatic or heteroaliphatic ammonium ion, for example morpholinium, thiomorpholinium, piperidinium, pyrrolidinium, or in each case protonated 1,4-diazabicyclo[2.2.2]octane (DABCO) or 1,5-diazabicyclo[4.3.0]undec-7-ene (DBU), or further \n is a heterocyclic ammonium cation, for example in each case protonated pyridine, 2-methylpyridine, 3-methylpyridine, 4-methylpyridine, 2,4-dimethylpyridine, 2,5-dimethylpyridine, 2,6-dimethylpyridine, 5-ethyl-2-methylpyridine, pyrrole, imidazole, quinoline, quinoxaline, 1,2-dimethylimidazole, 1,3-dimethylimidazolium methyl sulphate, or further \n is a sulphonium ion, or further \n is a magnesium halogen cation, \n m is the number 1, 2 or 3, n is the number 1, 2 or 3 and are reacted with a compound of formula (IV) in which R\u2032 is C 1 -C 6 -alkyl, q is the number 0 or 1, and Hal represents halogen, optionally in the presence of one or more solvents and optionally in the presence of an acid binder and optionally in the presence of a phase transfer catalyst.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 98.0
- Lexical Diversity: 1.2
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14387249', '15161978', '10525920', '12671548', '10497479']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7553185581698647
- 35 USC 102 Novelty (BERT): 0.5299825595204763
- Combined Prediction Score: 0.732784958304926
- Mean Citation Score: 317.7431160000001
- Max Citation Score: 346.90634
- Similarity Product: 305.12117498440983

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test