PATENT CLAIM ANALYSIS

Application Number: 16272788
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["546", "245000"]

Abstract:
The disclosed subject matter provides certain polymorphic forms of Compound (I) as well as pharmaceutical compositions comprising Compound (I) or such polymorphic forms, and methods of using or making such compounds and pharmaceutical compositions. It has now been discovered that Compound (I) can exist in multiple crystalline forms (polymorphs). One particular crystalline form, Form II, has been found to be more thermodynamically stable and, thus, likely more suitable for bulk preparation and handling than other polymorphic forms. Efficient and economic methods have been developed to prepare Compound (I) and Form II in high purity on a large scale. In animal studies, Form II has demonstrated safety and efficacy in treating depressive disorders and, when micronized, improved absorption compared to non-micronized Form II.

Claim (Index 17):
The method of  claim 16  further comprising heating the heptane solution to a temperature above 50\u00b0 C. but below the boiling point of heptane followed by cooling the heptane solution to room temperature.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 99.0
- Lexical Diversity: 1.70588
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15538015', '14604334', '13990632', '16301027', '15740719']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7242385883690606
- 35 USC 102 Novelty (BERT): 0.5126086585607184
- Combined Prediction Score: 0.7030755953882264
- Mean Citation Score: 213.96425
- Max Citation Score: 243.34459
- Similarity Product: 148.85456701846718

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test