PATENT CLAIM ANALYSIS

Application Number: 15934837
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["436", "501000"]

Abstract:
The invention relates to methods for providing prognosis, diagnosis, monitoring and treatment of a mild traumatic brain injury (mTBI) in a subject, including a sports-related concussion. The invention further relates to assessing the severity of brain damage resulting from mTBI in a subject, including in a subject who has not undergone a CT scan following the injury. For example, the methods of the invention can be used to determine the suitability for someone who has suffered a sports-related injury to return to play that sport. This invention also relates to methods of predicting risk for developing brain damage and long-term dysfunction in a subject having suffered mTBI.

Claim (Index 37):
A method for assessing severity of a concussion in a subject having suffered from a concussion, said method comprising:\n (a) obtaining a blood, serum, or plasma sample from said subject, within 36 hours of the concussion; (b) contacting said sample with an antibody that specifically binds to calpain-cleaved all-spectrin N-terminal fragment (SNTF) to form an antibody-SNTF complex; (c) measuring the amount of the antibody-SNTF complex, to determine SNTF concentration in the subject's serum or plasma; (d) comparing the serum or plasma concentration of SNTF in the subject to that of a pre-determined standard; and (e) assessing the severity of the concussion in the subject, wherein an elevated SNTF level in the subject relative to the standard is indicative of the severity of the concussion in the subject.

Metadata:
- Claim Count in Document: 109.0
- Percentile: 90.0
- Lexical Diversity: 1.87302
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14537642', '15391755', '14871232', '15802489', '15570982']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6236444758115145
- 35 USC 102 Novelty (BERT): 0.6359300538671775
- Combined Prediction Score: 0.6248730336170808
- Mean Citation Score: 366.4781059999999
- Max Citation Score: 620.06616
- Similarity Product: 574.2721822737408

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test