PATENT CLAIM ANALYSIS

Application Number: 15760874
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-03
Patent Classification: ["514", "04400A"]

Abstract:
A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise: introducing into an exosome-producing cell a nucleic acid construct comprising the nucleic acid sequence of interest incorporated in a pre-miR-451 structural mimic, and allowing the cell to produce exosomes. Nucleic acid constructs, compositions, and uses thereof are also provided.

Claim (Index 4):
The method according to  claim 1 , wherein the pre-miR-451 structural mimic comprises a stem-loop secondary structure having at least one base pair mismatch in the stem, such as at least one base pair mismatch in the stem positioned within the first three base pairs adjacent a Drosha cleavage site.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 90.0
- Lexical Diversity: 1.42
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13252784', '15451016', '14630419', '13642802', '12149725']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8265586358544337
- 35 USC 102 Novelty (BERT): 0.5495897972366212
- Combined Prediction Score: 0.7988617519926525
- Mean Citation Score: 393.004388
- Max Citation Score: 431.80292
- Similarity Product: 289.0108503721785

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test