PATENT CLAIM ANALYSIS

Application Number: 15883361
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["424", "489000"]

Abstract:
The present invention provides a preservative free ophthalmic formulation. In particular, the ophthalmic formulations of the invention are aqueous formulations comprising nanoemulsion of oil. The present invention also provides a method for treating an eye disorder. In one particular embodiment, the invention provides methods for treating dry eye syndrome using an preservative free formulation comprising a nanoemulsion of oil and alpha 2 adrenergic agonist, pharmaceutically acceptable salt thereof or a mixture thereof. In particular, the alpha 2 adrenergic agonist of the invention has a higher alpha 2A agonist activity compared to alpha 2B agonist activity. This invention also provides a preservative free ophthalmic composition comprising a nanoemulsion of oil, a therapeutically effective amount of an alpha 2 adrenergic agonist, a pharmaceutically acceptable salt thereof or a combination thereof as an active ingredient for treating a dry eye syndrome.

Claim (Index 14):
The method of  claim 10 , wherein said formulation is administered directly to the margin of the patient's eyelid.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 86.0
- Lexical Diversity: 2.45902
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15051654', '15464290', '11416929', '12024017', '12024014']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7541474934243343
- 35 USC 102 Novelty (BERT): 0.5558734000956789
- Combined Prediction Score: 0.7343200840914688
- Mean Citation Score: 314.43596
- Max Citation Score: 433.7014
- Similarity Product: 337.2398452105403

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test