PATENT CLAIM ANALYSIS

Application Number: 15757109
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "237800"]

Abstract:
The present invention relates to a novel compound having an effect of inhibiting platelet aggregation and a salt thereof and, more specifically, to: a novel platelet aggregation inhibitor specifically inhibiting shear stress-induced platelet aggregation; a pharmaceutical composition containing the same as an active ingredient; and a preparation method therefor.

Claim (Index 1):
A compound represented by the following Formula (I) or (II), or a pharmaceutically acceptable salt or isomer thereof: wherein, R 1  is hydroxy or C 1 -C 10  alkoxy; X is N or O; R 2  is \u2014(CH 2 ) p -5- to 12-membered heterocycle-(CH 2 ) p \u2014C 6 -C 12  aryl, 5- to 12-membered heterocycle, \u2014(CH 2 ) p \u2014NHC(\u2550O)\u2014C 6 -C 12  aryl, \u2014CHR 4 R 5 , 5- to 12-membered heteroaryl, C 6 -C 12  aryl, \u2014C 6 -C 12  aryl-O-5- to 12-membered heteroaryl, \u2014(CH 2 ) p -5- to 12-membered heteroaryl, or \u2014(CH 2 ) p \u2014C 6 -C 12  aryl, wherein p is an integer of 1 to 10; R 4  and R 5  are each independently C 1 -C 6  alkoxycarbonyl or \u2014CH 2 -5- to 12-membered heteroaryl; said heterocycle and heteroaryl may contain 1 to 3 heteroatoms selected from N, O and S; and said heterocycle, heteroaryl and aryl can be substituted with 1 to 4 substituents selected from the group consisting of halogen, oxo, aminocarbonyl, C 1 -C 6  alkyl, nitro, C 1 -C 6  alkoxy, nitrile, C 1 -C 6  alkylaminocarbonyl, hydroxy and hydroxy-C 1 -C 6  alkyl; R 3  is hydrogen; when X is O, R 3  does not exist; when X is N, X taken together with R 2  and R 3  may form a 5- to 12-membered heterocycle containing 1 to 3 heteroatoms selected from O, N and S; wherein said heterocycle can be substituted with C 6 -C 12  aryl; a 6- to 12-membered heteroaryl containing 1 to 3 heteroatoms selected from O, N and S, which is unsubstituted or substituted with halogen; or \u2014O\u2014CHR 6 R 7 ; and wherein R 6  and R 7  are each independently C 6 -C 12  aryl or a 6- to 10-membered heteroaryl containing 1 to 3 heteroatoms selected from N, O and S, both of which are unsubstituted or substituted with halogen.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 90.0
- Lexical Diversity: 1.44737
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10786610', '14913140', '13266976', '13542153', '14041387']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7885679863779165
- 35 USC 102 Novelty (BERT): 0.5221179530193117
- Combined Prediction Score: 0.7619229830420561
- Mean Citation Score: 287.3762
- Max Citation Score: 302.13028
- Similarity Product: 209.95788791203265

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test