PATENT CLAIM ANALYSIS

Application Number: 15750108
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["435", "325000"]

Abstract:
A method of generating retinal pigment epithelium cells is disclosed. Cell populations comprising same and uses thereof are also disclosed.

Claim (Index 1):
A method of generating retinal pigment epithelial (RPE) cells comprising:\n (a) culturing a population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; (b) culturing said differentiating cells in a culture comprising a medium which comprises one or more members of the TGF\u03b2 superfamily, thereby generating a mixed population of cells comprising RPE cells; (c) removing said mixed population of cells from said culture, wherein more than 10% of the cells of said mixed populations of cells are non-pigmented cells; and subsequently; (d) culturing said mixed population of cells on an adherent surface to generate an expanded population of RPE cells; and (e) harvesting said expanded populations of RPE cells, thereby generating the RPE cells.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 88.0
- Lexical Diversity: 1.1
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14375195', '13510426', '12450943', '14254833', '15143141']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5332982792803315
- 35 USC 102 Novelty (BERT): 0.5271652220251231
- Combined Prediction Score: 0.5326849735548106
- Mean Citation Score: 296.909168
- Max Citation Score: 340.32227
- Similarity Product: 270.8829779798341

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test