PATENT CLAIM ANALYSIS

Application Number: 15860506
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "186100"]

Abstract:
Methods for determining the susceptibility or resistance of bacteria to antibiotic agents are provided. In one embodiment, the methods include culturing the bacteria in the presence or absence or the antimicrobial agent to generate a primary culture which is then cultured in the presence or absence of transforming phages. The recombinant phages are specific to the bacteria and comprise a heterologous marker (e.g., a nucleic acid that is expressible as a detectable product such as an RNA or a protein). The susceptibility or resistance of the bacteria to the antimicrobial agent may be determined by assaying the culture for the presence or absence of the heterologous marker, wherein a reduction in the level or activity of the marker in the culture compared to the level or activity of the marker in a comparative culture indicates that the bacteria is sensitive to the antibiotic agent.

Claim (Index 15):
The method of  claim 14 , wherein a reduction in the level or activity of the marker in the first transformed secondary culture compared to the level or activity of the marker in the second transformed secondary culture indicates that the bacteria is susceptible to the test antimicrobial agent.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 2.15493
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12812212', '09600398', '14119716', '13224776', '15161857']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7509176873117825
- 35 USC 102 Novelty (BERT): 0.4968471800407961
- Combined Prediction Score: 0.7255106365846838
- Mean Citation Score: 216.71058
- Max Citation Score: 220.99445
- Similarity Product: 153.40218458765744

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test