PATENT CLAIM ANALYSIS

Application Number: 15758098
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "312000"]

Abstract:
The present invention relates in a first aspect to compounds for use in the treatment of leukodystrophy whereby these compounds are quinoline derivatives, e.g. laquinimod. In a further aspect, the present invention relates to methods for the treatment of Leukodystrophy, in particular, peroxisomal disorders including Zellweger syndrome.

Claim (Index 31):
The method of  claim 29  wherein the compound is a compound of general formula (IV) wherein n is an integer of 1, 2 or 3; A n + is a mono- or multivalent metal cation selected from Li + , Na + , K + , Mg 2+ , Ca 2+ , Mn 2+ , Cu 2+ , Zn 2+ , Al 3+  and Fe 3+ ; R 13  is a straight or branched C 1 -C 4 -alkyl or -alkenyl or a cyclic C 3 -C 4 -alkyl; R 1  and R 2  are the same or different and selected from hydrogen, straight or branched, saturated or unsaturated C 1 -C 6 -alkyl or -alkenyl, a cyclic C 3 -C 6 -alkyl, a straight or branched C 1 -C 6 -alkylthio, a cyclic C 3 -C 6 -alkylthio, a straight or branched C 1 -C 6 -alkylsulfinyl, a cyclic C 3 -C 6 -alkylsulfinyl, fluoro, chloro, bromo, trifluoromethyl or trifluoromethoxy; and/or R 1  and R 2  taken together are methylenedioxy; R 15  is hydrogen, a straight or branched, saturated or unsaturated C 1 -C 4 -alkyl or -alkenyl, a cyclic C 3 -C 4 -alkyl, a straight or branched C 1 -C 4 -alkoxy, a cyclic C 3 -C 4 -alkoxy, fluoro, chloro, bromo or trifluoromethyl; and R 16  is hydrogen, fluoro or chloro, with the proviso that R 16  is fluoro or chloro only when R 15  is fluoro or chloro; optionally, an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 90.0
- Lexical Diversity: 1.54286
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13417030', '14182994', '13417028', '11482926', '16301711']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7133466602713784
- 35 USC 102 Novelty (BERT): 0.5010370016617406
- Combined Prediction Score: 0.6921156944104147
- Mean Citation Score: 176.222894
- Max Citation Score: 180.24554
- Similarity Product: 116.70587841912032

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test