PATENT CLAIM ANALYSIS

Application Number: 15761808
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["356", "436000"]

Abstract:
One or more homogenizing elements are employed in a flow through, multi-detector optical measurement system. The homogenizing elements correct for problems common to multi-detector flow-through systems such as peak tailing and non-uniform sample profile within the measurement cell. The homogenizing elements include coiled inlet tubing, a flow distributor near the inlet of the cell, and a flow distributor at the outlet of the cell. This homogenization of the sample mimics plug flow within the measurement cell and enables each detector to view the same sample composition in each individual corresponding viewed sample volume. This system is particularly beneficial when performing multiangle light scattering (MALS) measurements of narrow chromatographic peaks such as those produced by ultra-high pressure liquid chromatography (UHPLC).

Claim (Index 20):
A method for measuring the properties of a particle bearing liquid sample comprising the steps of\n A. preparing said particle bearing liquid sample to be analyzed; B. allowing said sample to flow from said separation means to a detection instrument through a length of tubing, said detection instrument comprising\n a. a transparent optical measurement cell comprising\n i. a bore through which passes said sample; \n ii. a sample inlet into said bore; and \n iii. a sample outlet from said bore; \n \n b. a means to illuminate said sample within said bore; and \n c. a plurality of photo detectors positioned so as detect an optical signal from said illuminated sample; \n C. homogenizing said sample prior to its passage through said optical measurement cell by flowing said sample through one or more of a group of homogenizing elements, said homogenizing elements selected from the group consisting of\n a. a coiled tube connected to said sample inlet where the ratio of bend radius to bore radius of said coiled tube is less than 50; \n b. a flow distributor through which said liquid sample passes prior to entry into said bore; and \n c. a flow distributor through which said liquid sample passes subsequent to exiting said bore; \n D. illuminating said sample; E. collecting simultaneous optical signals from said illuminated sample with said photo detectors; and F. analyzing said collected optical signals to determine the physical properties of said liquid sample.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 90.0
- Lexical Diversity: 1.59756
- Patent Class: 356.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13896120', '15727398', '10665903', '12148358', '13480590']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.652974248736837
- 35 USC 102 Novelty (BERT): 0.4896244097344607
- Combined Prediction Score: 0.6366392648365993
- Mean Citation Score: 193.25978
- Max Citation Score: 230.60968
- Similarity Product: 185.011268105793

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test