PATENT CLAIM ANALYSIS

Application Number: 15959498
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-09
Patent Classification: ["435", "252300"]

Abstract:
The present disclosure relates to a recombinant gram-negative bacterial cell comprising: a) a mutant spr gene encoding a spr protein having a mutation at one or more amino acids selected from D133, H145, H157, N31, R62, I70, Q73, C94, S95, V98, Q99, R100, L108, Y115, V135, L136, G140, R144 and G147 and b) a gene capable of expressing or overexpressing one or more proteins capable of facilitating protein folding, such as FkpA, Skp, SurA, PPiA and PPiD, wherein the cell has reduced Tsp protein activity compared to a wild-type cell, methods employing the cells, use of the cells in the expression of proteins in particular antibodies, such as anti FcRn antibodies and proteins made by the methods described herein.

Claim (Index 19):
The method according to  claim 18 , wherein the protein of interest is recovered from the periplasm and/or the supernatant.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.70115
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14400068', '14633294', '13522083', '14633257', '13522080']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7228837134783135
- 35 USC 102 Novelty (BERT): 0.602650417164689
- Combined Prediction Score: 0.7108603838469512
- Mean Citation Score: 506.0154480000001
- Max Citation Score: 531.3349
- Similarity Product: 505.991910216832

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test