PATENT CLAIM ANALYSIS

Application Number: 15994786
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "007100"]

Abstract:
A method of bioassay for the quantification of peptide fragments elevated in lung diseases such as COPD, SCC, or IPF, comprising a neo-epitope formed at a cleavage site by cleavage in vivo of elastin by a proteinase by contacting a sample with an antibody having specific binding affinity for a the neo-epitope amino acid sequence and determining the level of binding, where the antibody binds one of the following terminal sequences: ...FGPGVV   ...VPGLGV   IKAPKL... and antibodies and immunoassay kits for use in such methods.

Claim (Index 1):
An immunological binding partner specifically reactive with one of the following C-terminal sequences derived from elastin: (SEQ\u2003ID\u2003NO:\u20032) FGPGVV||'334   (SEQ\u2003ID\u2003NO:\u20033) VPGLGV||'602 or reactive with the following N-terminal sequence derived from elastin: (SEQ\u2003ID\u2003NO:\u20034) 208'||IKAPKL wherein the immunological binding partner not specifically reactive with the sequence ... ... ...FGPGVVG (SEQ ID NO:5) if it is reactive with ... ... ...FGPGVV (SEQ ID NO: 2), and is not specifically reactive with ... ... ...VPGLGVG (SEQ ID NO: 6) if it is reactive with ... ... ...VPGLGV (SEQ ID NO: 3), and is not specifically reactive with PIKAPKL... ... (SEQ ID NO: 7) if it is reactive with IKAPKL... ... (SEQ ID NO: 4).

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 1.47619
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15111062', '12749652', '14116924', '14960713', '15446070']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6329274806779539
- 35 USC 102 Novelty (BERT): 0.5670231112236875
- Combined Prediction Score: 0.6263370437325273
- Mean Citation Score: 374.239376
- Max Citation Score: 611.0979
- Similarity Product: 326.8707361066282

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test