PATENT CLAIM ANALYSIS

Application Number: 16013795
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["530", "323000"]

Abstract:
The invention describes peptide ligands specific for human plasma Kallikrein.

Claim (Index 1):
A peptide ligand specific for human Kallikrein comprising a polypeptide comprising three reactive groups, separated by two loop sequences, and a molecular scaffold which forms covalent bonds with the reactive groups of the polypeptide such that two polypeptide loops are formed on the molecular scaffold, wherein the loops of the peptide ligand comprise five amino acids and wherein the polypeptide comprises the motif G r x 1 x 2 x 3 x 4 x 5 G rx x 6 x 7 x 8 x 9 x 10 G r , wherein x 1  and x 9  are independently any amino acid, x 2  is tryptophan or phenylalanine, x 3  is proline or azetidine carboxylic acid, x 4  is alanine or tyrosine, x 5  is arginine, N-methyl arginine, homoarginine, or guanidylphenylalanine, x 6  is tyrosine, leucine or alanine, x 7  is histidine, x 8  is glutamine or threonine, x 10  is leucine, and Gr represents cysteine; and wherein optionally one or more peptide bonds are replaced by \u03c8CH 2 NH.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 94.0
- Lexical Diversity: 1.0
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14781294', '14350263', '15029248', '14849637', '14339327']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6861574914513885
- 35 USC 102 Novelty (BERT): 0.6525971615916469
- Combined Prediction Score: 0.6828014584654144
- Mean Citation Score: 387.978304
- Max Citation Score: 657.2139
- Similarity Product: 605.2096649358092

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test