PATENT CLAIM ANALYSIS

Application Number: 15974469
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "043000"]

Abstract:
The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions for treatment of viral infections, especially HRV.

Claim (Index 1):
A compound of formula (I): wherein: R 1  is H, Me, Et, iPr, or cyclopropyl; R 2  is H, phosphate, diphosphate, triphosphate, \u2014P(\u2550X)(OR 4 ) 2 , \u2014P(\u2550X)(OR 4 )(NR 5 R 6 ), or \u2014P(\u2550X)(NR 5 R 6 ) 2 , and R 3  is H or \u2014C(O)R;\n or R 3  and R 2  taken together form \u2014P(\u2550X)(OR 4 )\u2014 or \u2014P(\u2550X)(NR 5 R 6 ) \u2212 ; \n X at each occurrence is independently O or S; \n R 4  is selected from H, phenyl optionally substituted with one or two groups selected from List A, and C 1 -C 4  alkyl optionally substituted with one or two groups selected from halo, \u2014OR, \u2014OC(O)R, \u2014OC(O)\u2014OR, \u2014NR 2 , \u2014C(O)R, COOR and \u2014C(O)NR 2 ; \n each R 5  is independently H, \u2014C(O)R, COOR, or C 1 -C 4  alkyl optionally substituted with OH, amino, or COOR; \n each R 6  is independently selected from H, phenyl optionally substituted with one or two groups selected from List A, and C 1 -C 4  alkyl optionally substituted with one or two groups selected from List B; \n each R is independently H or a C 1 -C 4  alkyl group optionally substituted with one to three groups selected from halo, hydroxy, CN, amino, C 1 -C 3  alkoxy, \u2014C(O)R 7 , \u2014OC(O)R 7 , \u2014C(O)\u2014OR 7 , or \u2014OC(O)\u2014OR 7 ; \n R 7  is selected from H, C 1 -C 4  alkyl optionally substituted with one to three groups selected from halo, hydroxy, CN, amino, and C 1 -C 3  alkoxy, or phenyl optionally substituted with one or two groups selected from List A; \n List A is halo, hydroxy, \u2014NO 2 , CN, \u2014OR 8 , \u2014OC(O)R 8 , \u2014OC(O)\u2014OR 8 , \u2014N(R 8 ) 2 , \u2014C(O)R 8 , COOR 8 , \u2014C(O)N(R 8 ) 2 , and C 1 -C 3  alkyl optionally substituted with one to three groups selected from halo, hydroxy, CN, amino, and C 1 -C 3  alkoxy; \n List B is halo, hydroxy, oxo, CN, \u2014OR 8 , \u2014OC(O)R 8 , \u2014OC(O)\u2014OR 8 , \u2014N(R 8 ) 2 , \u2014C(O)R 8 , COOR 8  and \u2014C(O)N(R 8 ) 2 ; and \n R 8  is independently at each occurrence selected from H and C 1 -C 4  alkyl optionally substituted with one to three groups selected from halo, hydroxy, CN, amino, and C 1 -C 3  alkoxy, \n and two R 8  attached to the same nitrogen atom can optionally cyclize to form a 3-7 membered heterocycle, which optionally contains an additional N, O or S as a ring member, and can be substituted by one or two groups selected from oxo, halo, \u2014OH, amino, C 1 -C 3  alkyl, C 1 -C 3  alkoxy, and C 1 -C 3  haloalkyl; \n or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 1.62162
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15465485', '15686652', '15718571', '14527328', '14890719']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7880454233557124
- 35 USC 102 Novelty (BERT): 0.5665778726752125
- Combined Prediction Score: 0.7658986682876624
- Mean Citation Score: 300.2443140000001
- Max Citation Score: 433.4615
- Similarity Product: 425.192767044276

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test