PATENT CLAIM ANALYSIS

Application Number: 16177670
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["424", "457000"]

Abstract:
Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance (e.g., a therapeutic agent), and, optionally, a linker. In some such embodiments, the linker may be configured to degrade such that the residence structure breaks apart and is released from the location internally of the subject after a predetermined amount of time.

Claim (Index 84):
An article, comprising:\n a containing structure; and (New) A residence structure contained within the containing structure, the residence structure comprising a loadable polymeric component and a second polymeric component coupled to the loadable polymeric component by at least one degradable linker, wherein the residence structure is constructed and arranged to undergo elastic recoil upon release from the containing structure, the residence structure having a first configuration when contained within the containing structure and a second configuration after release from the containing structure.

Metadata:
- Claim Count in Document: 227.0
- Percentile: 98.0
- Lexical Diversity: 2.38406
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16177704', '16014549', '15317566', '12937955', '15317601']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7859989914005365
- 35 USC 102 Novelty (BERT): 0.5802251847751393
- Combined Prediction Score: 0.7654216107379969
- Mean Citation Score: 402.451056
- Max Citation Score: 548.1045
- Similarity Product: 394.4112404123247

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test