PATENT CLAIM ANALYSIS

Application Number: 15975516
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["506", "016000"]

Abstract:
Disclosed herein, are compositions, methods, and kits comprising engineered reverse transcription enzymes that exhibit several desired properties such as thermal stability, processive reverse transcription, non-templated base addition, and template switching ability. The engineered reverse transcription enzymes described herein demonstrate unexpectedly higher resistance to cell lysate inhibition, greater ability to capture full-length mRNA transcripts, and demonstrate improved results in small reaction volumes as compared to other engineered reverse transcription enzymes.

Claim (Index 24):
The method of  claim 22 , wherein said RNA molecule is a messenger RNA (mRNA) molecule, wherein said reaction volume further comprises a nucleic acid molecule comprising an oligo(dT) sequence, wherein said plurality of nucleic acid barcode molecules further comprise a template switching sequence, wherein said engineered reverse transcription enzyme reverse transcribes said mRNA molecule using said nucleic acid molecule comprising said oligo(dT) sequence, and wherein said engineered reverse transcription enzyme performs a template switching reaction, thereby generating said complementary DNA molecule, wherein said complementary DNA molecule comprises said barcode sequence.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 93.0
- Lexical Diversity: 1.49057
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14603256', '11502819', '15832183', '15933299', '15847752']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5690449076327646
- 35 USC 102 Novelty (BERT): 0.5284372824971749
- Combined Prediction Score: 0.5649841451192057
- Mean Citation Score: 293.44033
- Max Citation Score: 360.6068
- Similarity Product: 320.72951467654707

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test