PATENT CLAIM ANALYSIS

Application Number: 15918195
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "210210"]

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Claim (Index 9):
The compound of  claim 3  having Formula (VII): or a stereoisomer, tautomer, pharmaceutically acceptable salt thereof, wherein:\n R 1b  is selected from the group consisting of: H and F; \n is selected from the group consisting of: R 2  is selected from the group consisting of: H, F, CN, COMe, OH, OMe, OCHF 2 , CHF 2 , CF 3 , and tetrazole; R 3  is selected from the group consisting of: phenyl substituted with 1-2 R 3a , cyclohexyl, R 3a  is independently selected from the group consisting of: H, F, C, CN, CO 2 H, \u2014CH 2 CO 2 H, CO 2 Me, \u2014CO 2 Et, \u2014CO 2 (i-Pr), \u2014CO 2 (t-Bu), \u2014CO 2 (n-Bu), \u2014CO 2 (i-Bu), \u2014CO 2 (CH 2 ) 2 OMe, \u2014CO 2 CH 2 CON(Me) 2 , \u2014NHCO 2 Me, \u2014CO 2 (CH 2 ) 2 -triazole, and \u2014CO 2 (cyclopentyl); R 4c  and R 4d  are independently selected from the group consisting of: H and Me; R 5b  and R 5c  are, independently selected from the group consisting of: H, F, Me, Et, i-propyl, CN, OH, \u2014OMe, \u2014CO 2 Me, \u2014CO 2 Et, \u2014CON(Me) 2 , NH 2 , \u2014N(Me) 2 , \u2014O(CH 2 )N(Me) 2 , \u2014O(CH 2 )OMe, R 6  is selected from the group consisting of: H, Me, \u2014CO 2 Me, \u2014CO 2 (t-butyl), \u2014COMe, \u2014CONHMe, \u2014CONH(CH 2 ) 2 CO 2 Et, CONH(CH 2 ) 2 N(Me) 2 , \u2014CO 2 CH 2 Ph, \u2014(CH 2 ) 2 N(Me) 2 , and \u2014CH 2 Ph; R 7  is selected from the group consisting of: H and Me; q, at each occurrence, is selected from 0, 1, and 2; and r, at each occurrence, is selected from 0, 1, and 2.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 90.0
- Lexical Diversity: 1.17949
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14117513', '15361589', '14617979', '14886415', '14350411']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8634974212272201
- 35 USC 102 Novelty (BERT): 0.6542748770424888
- Combined Prediction Score: 0.842575166808747
- Mean Citation Score: 542.883702
- Max Citation Score: 635.02765
- Similarity Product: 618.9345979087918

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test