PATENT CLAIM ANALYSIS

Application Number: 16439620
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-09
Patent Classification: ["210", "645000"]

Abstract:
A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

Claim (Index 48):
A method of treating a cancer in a liver of a patient in need of treatment, comprising:\n introducing a first catheter into a femoral artery to provide access to a region of the proper hepatic artery; guiding the first catheter to within the region of the proper hepatic artery to deliver melphalan hydrochloride; inserting an isolation-aspiration catheter having two balloons into the femoral vein and guiding the isolation-aspiration catheter into the inferior vena cava; inflating the two balloons to block normal venous outflow of blood from the liver to isolate the liver; delivering a dose of melphalan to the liver via the first catheter over a period of from about 15 minutes to about 45 minutes; collection melphalan-laden blood as it exits the liver in the region between the two inflated balloons of the isolation-aspiration catheter; passing the melphalan-laden blood through a filter apparatus at a rate of between about 250 ml/min and about 1000 ml/min, wherein the filter apparatus comprises a housing having an inlet and an outlet, an extraction media comprising hemocompatible polymer coated carbon cores contained within the housing, and wherein the carbon cores have a pore volume of about 1.68 cc/g to about 2.17 cc/g, and returning blood that has passed through the filter apparatus and has been filtered to the patient.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 100.0
- Lexical Diversity: 1.71698
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16127008', '13671549', '15651141', '14013005', '12815453']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7741057614683782
- 35 USC 102 Novelty (BERT): 0.5585918990812422
- Combined Prediction Score: 0.7525543752296646
- Mean Citation Score: 335.753452
- Max Citation Score: 448.582
- Similarity Product: 328.51300806748867

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test