PATENT CLAIM ANALYSIS

Application Number: 16216420
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "318000"]

Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Claim (Index 1):
A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein X is N or CH; Y is N; A is CH 2 ; B is O or CR 7 R 8 ; Z 1  is CR 4  or N; R is hydrogen, C 1 -C 4 alkyl, monofluoromethyl, difluoromethyl or trifluoromethyl; R 1  is hydrogen, halogen, C 1 -C 4 alkyl or trifluoromethyl; R 2  is piperidinyl which is N-substituted with C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, haloC 1 -C 4 alkyl, C(O)C 1 -C 4 alkyl, S(O) 2 C 1 -C 4 alkyl, C(O)C 3 -C 6 cycloalkyl, C(O)haloC 1 -C 4 alkyl, C(O)C 1 -C 4 alkoxy, C(O)C 1 -C 4 alkenoxy, heteroaryl or CO(O) 2 benzyl, wherein each cycloalkyl is optionally substituted by hydroxy and each alkyl or alkoxy is optionally substituted by hydroxyl, C 1 -C 4 alkoxy or C 3 -C 6 cycloalkyl and wherein each heteroaryl has 5 or 6 ring atoms, 1, 2 or 3 ring heteroatoms independently selected from N, O and S and is optionally substituted with 1 or 2 C 1 -C 4 alkyl substituents. R 3  is hydrogen, halogen or C 1 -C 4 alkyl; or R 2  and R 3 , taken in combination, form a 5 or 6 member fused saturated azacyclic ring optionally substituted with benzyl or 5 or 6 member heteroarylmethyl, which heteroaryl has 1 or 2 ring heteroatoms independently selected from N, O and S; R 4  is hydrogen or C 1 -C 4 alkyl; R 5  is hydrogen, halogen, C 1 -C 4 alkyl or C 3 -C 6 cycloalkyl; R 7  is hydrogen or C 1 -C 4 alkyl; or R 7  and R 9 , taken in combination with the ring atoms to which they are attached form a carbon-carbon double bond; R 8  is hydrogen or C 1 -C 4 alkyl; and R 1  is hydrogen or C 1 -C 4 alkyl.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.4
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15320810', '15320813', '15320815', '16063059', '15911797']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8327713214821341
- 35 USC 102 Novelty (BERT): 0.5642079206379194
- Combined Prediction Score: 0.8059149813977126
- Mean Citation Score: 389.451514
- Max Citation Score: 427.36118
- Similarity Product: 418.0852921711135

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test