PATENT CLAIM ANALYSIS

Application Number: 15742027
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["427", "002100"]

Abstract:
An asymmetric immobilization process that immobilizes a one or more receptor biomolecules on one or more solid surfaces is provided. The asymmetric immobilization process includes the following steps: (i) activating the one or more solid surfaces using an oxidizing agent; (ii) treating the one or more solid surfaces with aminosilane to obtain a one or more amine functionalized solid surfaces; (iii) treating the one or more receptor biomolecules with a 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) to obtain a one or more site-specific EDC activated receptor biomolecules; and (iv) immobilizing the one or more site-specific EDC activated receptor biomolecules on a first layer of the one or more amine functionalized solid surfaces, wherein the immobilizing comprises treating the one or more site-specific EDC activated receptor biomolecules with amine groups of the first layer of the one or more amine functionalized solid surfaces to form a covalent amide bond.

Claim (Index 3):
The asymmetric immobilization process as claimed in  claim 1 , wherein the asymmetric immobilization process comprises:\n coating a second region of the plurality of amine functionalized solid surfaces with an amine blocker; washing the plurality of amine functionalized solid surfaces using organic solvents after treating the plurality of solid surfaces with the aminosilane; washing the plurality of site-specific EDC activated receptor biomolecules that are excess from the plurality of amine functionalized solid surfaces using at least one of (a) phosphate buffer saline, (b) de-ionised water after immobilizing the plurality of site-specific EDC activated receptor biomolecules on the plurality of amine functionalized solid surfaces; and treating the first region of the plurality of amine functionalized solid surfaces with bovine serum albumin to block unbound amine groups of the plurality of amine functionalized solid surfaces.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 86.0
- Lexical Diversity: 2.66129
- Patent Class: 427.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12317713', '10293260', '12119203', '11621209', '09845742']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8062299323591732
- 35 USC 102 Novelty (BERT): 0.5085556646634761
- Combined Prediction Score: 0.7764625055896035
- Mean Citation Score: 198.672414
- Max Citation Score: 231.09346
- Similarity Product: 148.0787385184574

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test