PATENT CLAIM ANALYSIS

Application Number: 15769844
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "227800"]

Abstract:
A compound represented by general formula [I] wherein X represents N or the like, Y represents CH or the like; R A  represents a cycloalkyl group which may be substituted or the like, R 1  represents an alkyl group or the like, R 2  represents an alkyl group which may be substituted or the like, R 3  represents a hydrogen atom or an alkyl group, or a pharmaceutically acceptable salt thereof has an inhibitory activity on aldosterone synthetase, and is useful as a prophylactic and/or therapeutic agent for various diseases or symptoms associated with aldosterone.

Claim (Index 5):
The compound according to  claim 4 , wherein\n R A  is (1) a cycloalkyl group which may be substituted with an alkyl group, (2) a cycloalkenyl group which may be substituted with an alkyl group, (3) a phenyl group which may be substituted with 1-3 groups independently selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an alkoxyalkyl group, and an alkoxy group, (4) a naphthyl group, or (5) a heteroaryl group which may be partially hydrogenated and may be substituted with 1-2 groups independently selected from the group consisting of a cyano group, an alkyl group, and a haloalkyl group, in the heteroaryl group which may be partially hydrogenated and may be substituted, represented by R A , the heteroaryl moiety is pyridyl, indazolyl, or benzofuranyl, R 1  is a hydrogen atom, or an alkyl group, R 2  is (i) an alkyl group which may be substituted with 1-3 groups independently selected from the group consisting of a hydroxyl group; a halogen atom; and an aliphatic heterocyclic group which may be substituted with 1-2 substituents independently selected from the group consisting of a hydroxyl group, an oxo group, an alkyl group, an alkoxycarbonyl group, and an alkylsulfonyl group (wherein the aliphatic heterocyclic group is a piperidinyl group, a piperazinyl group, a morpholinyl group, or a thiomorpholinyl group), (ii) a cycloalkyl group which may be substituted with 1-3 groups independently selected from the group consisting of a hydroxyl group; an alkyl group which may be substituted with a hydroxyl group; an alkoxy group which may be substituted with a carbamoyl group which may be substituted with 1-2 alkyl groups; an amino group which may be substituted with 1-2 groups independently selected from the group consisting of an alkyl group, and an alkanoyl group; and an aliphatic heterocyclic group which may be substituted with 1-2 groups independently selected from the group consisting of a hydroxyl group, and an oxo group (wherein the aliphatic heterocyclic group is a piperidinyl group, a morpholinyl group, or a piperazinyl group), (iii) an aliphatic heterocyclic group which may be substituted with 1-3 groups independently selected from the group consisting of a halogen atom; a hydroxyl group; an oxo group; an alkyl group which may be substituted with 1-2 groups independently selected from the group consisting of a carbamoyl group which may be substituted with 1-2 alkyl groups, a hydroxyl group, and an alkylsulfonyl group; an alkoxy group; an alkoxycarbonyl group; a tetrahydropyranyl group; and a pyrimidinyl group, or (iv) a heteroaryl group which may be partially hydrogenated and may be substituted with an alkyl group which may be substituted with a carbamoyl group which may be substituted with 1-2 alkyl groups, in the aliphatic heterocyclic group which may be substituted, represented by R 2 , the aliphatic heterocyclic moiety is pyrrolidinyl, piperidinyl, tetrahydrothiopyranyl, tetrahydropyranyl, 1-azabicyclo[2.2.2]octyl(quinuclidinyl), 8-azabicyclo[3.2.1]octyl, 3-oxabicyclo[3.3.1]nonyl, or 3-oxo-9-azabicyclo[3.3.1]nonyl, in the heteroaryl group which may be partially hydrogenated and may be substituted, represented by R 2 , the heteroaryl moiety is pyrazolyl, pyridyl, or benzimidazolyl, and R 3  is a hydrogen atom, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 91.0
- Lexical Diversity: 1.75
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15305587', '15313407', '15779435', '10583796', '13508905']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.817299060508435
- 35 USC 102 Novelty (BERT): 0.5581812604323418
- Combined Prediction Score: 0.7913872805008257
- Mean Citation Score: 322.9079480000001
- Max Citation Score: 436.3854
- Similarity Product: 369.0602476422072

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test