PATENT CLAIM ANALYSIS

Application Number: 15876821
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "04400R"]

Abstract:
Expression vectors and therapeutic methods of using such vectors in the treatment of diseases of the eye resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye.

Claim (Index 11):
The method of  claim 10 , wherein the one or more supportive therapies is selected from the group consisting of: surgery, laser therapy (e.g., photocoagulation), anti-angiogenic therapy, VEGF inhibitors such as bevacizumab (Avastin\u2122), ranibizumab (Lucentis\u2122) and Aflibercept (Eylea\u2122), Ca2+ inhibitors (e.g., flunarizine and nifedipine), cryotherapy, hyperbaric oxygenation, Na+ channel blockers (e.g., topiramate), iGluR antagonists (e.g., MK-801, dextromethorphan, eliprodil, and flupirtine), antioxidants (e.g., dimethylthiourea, vitamin E, alph-lipoic acid, superoxide dismutase, catalase, desferrioxamine, mannitol, allopurinol, calcium dobesilate, flupirtine, trimetazidine), anti-inflammatory agents, cyclodiathermy, cyclocryotherapy, ocular filtering procedures, implantation of drainage valves, antiplatelet therapy (e.g., aspirin, ticlopidine, clopidogrel), anticoagulant therapy (e.g., warfarin and heparin), steroids, systemic or local corticosteroids (e.g., prednisone triamcinolone (Triesence\u2122), and dexamethasone, steroid-sparing immunosuppressants (e.g., cyclosporine, azathioprine, cyclophosphamide, mycophenolate, mofetil, infliximab and etanercept), dietary supplements (e.g., vitamin C, vitamin E, lutein, zinc, folic acid, vitamin B6, vitamin B12, vitamin D, calcium, zeaxanthin), vitrectomy, scleral buckle surgery, pneumatic retinopexy, ciliary neurotrophic factor (CNTF) protein, brain-derived neurotrophic factor (BDNF) protein, pigment epithelium-derived factor (PEDF) protein, and lens epithelial derived growth factor (LEDGF).

Metadata:
- Claim Count in Document: 38.0
- Percentile: 86.0
- Lexical Diversity: 1.53846
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14766842', '14660657', '12366596', '13212078', '13388083']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7492650447587172
- 35 USC 102 Novelty (BERT): 0.5827465031470652
- Combined Prediction Score: 0.7326131905975521
- Mean Citation Score: 352.866614
- Max Citation Score: 571.0919
- Similarity Product: 355.2501259721637

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test