PATENT CLAIM ANALYSIS

Application Number: 15908214
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-07
Patent Classification: ["426", "590000"]

Abstract:
Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.

Claim (Index 30):
A recombinant host cell capable of producing Rebaudioside M, the cell comprising:\n (a) a gene encoding a polypeptide capable of synthesizing geranylgeranyl pyrophosphate (GGPP) from farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP); (b) a gene encoding a polypeptide capable of synthesizing ent-copalyl diphosphate from GGPP; (c) a gene encoding a polypeptide capable of synthesizing ent-kaurene from ent-copalyl pyrophosphate; (d) a gene encoding a polypeptide capable of synthesizing ent-kaurenoic acid from ent-kaurene; (e) a gene encoding a polypeptide capable of synthesizing steviol from ent-kaurenoic acid; (f) a gene encoding a polypeptide capable of reducing cytochrome P450 complex; (g) a first gene encoding a first polypeptide capable of beta 1,2 glycosylation of the C2\u2032 of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of a steviol glycoside, wherein the first polypeptide comprises a polypeptide having 65% or greater sequence identity to the amino acid sequence set forth in SEQ ID NO:16; (h) a second gene encoding a second polypeptide capable of beta 1,2 glycosylation of the C2\u2032 of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of a steviol glycoside, wherein the second polypeptide comprises a polypeptide having 90% or greater sequence identity to the amino acid sequence set forth in SEQ ID NOs:15 or 86, a polypeptide having a substitution at residues 211 and 286 of SEQ ID NO:15, or a combination thereof; (i) a gene encoding a polypeptide capable of beta 1,3 glycosylation of the C3\u2032 of the 13-O-glucose, 19-O-glucose, or both 13-O-glucose and 19-O-glucose of the steviol glycoside; (j) a gene encoding a polypeptide capable of glycosylating steviol or the steviol glycoside at its C-13 hydroxyl group; and (k) a gene encoding a polypeptide capable of glycosylating steviol or the steviol glycoside at its C-19 carboxyl group, wherein at least one of the genes is a recombinant gene.

Metadata:
- Claim Count in Document: 80.0
- Percentile: 88.0
- Lexical Diversity: 1.05882
- Patent Class: 426.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14761629', '15541686', '15328365', '15506196', '14764898']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7836931835819352
- 35 USC 102 Novelty (BERT): 0.8024853398400419
- Combined Prediction Score: 0.7855723992077459
- Mean Citation Score: 812.8713019999999
- Max Citation Score: 1052.9233
- Similarity Product: 997.40947001127

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test