PATENT CLAIM ANALYSIS

Application Number: 15887469
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "717000"]

Abstract:
Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.

Claim (Index 51):
The method of  claim 27  or  28 , wherein the parasite is an  Acanthamoeba  species,  Balamuthia mandrillaris, B. divergens, B. bigemina, B. equi, B. microfti, B. duncani, Balantidium coli,  a  Blastocystis  species, a  Cryptosporidium  species,  Cyclospora cayetanensis, Dientamoeba Entamoeba histolytica, Giardia lamblia, Isospora belli,  a  Leishmania  species,  Naegleria fowleri, Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale curtisi, Plasmodium ovale wallikeri, Plasmodium malariae, Plasmodium know lesi, Rhinosporidium seeberi, Sarcocystis bovihominis, Sarcocystis suihominis, Toxoplasma gondii, Trichomonas vaginalis, Trypanosoma brucei, Trypanosoma cruzi, Cestoda, Taenia multiceps, Diphyllobothrium latum, Echinococcus granulosus, Echinococcus multilocularis, E. vogeli, E. oligarthrus, Hymenolepis nana, Hymenolepis diminuta, Taenia saginata, Taenia solium, Bertiella mucronata, Bertiella studeri, Spirometra erinaceieuropaei, Echinostoma echinatum, Schistosoma mekongi, Opisthorchis viverrini, Opisthorchis felineus, Clonorchis sinensis, Clonorchis sinensis; Clonorchis viverrini, Fasciolopsis buski, Schistosoma mansoni, Schistosoma intercalatum, Dicrocoelium dendriticum, Fasciola hepatica, Fasciola gigantica, Metagonimus yokogawai, Metorchis conjunctus, Paragonimus westermani, Paragonimus africanus, Paragonimus caliensis, Paragonimus kellicotti, Paragonimus skrjabini, Paragonimus uterobilateralis, Schistosoma japonicum,  a  Schistosoma  species,  Trichobilharzia regenti, Schistosomatidae, Schistosoma haematobium, Ancylostoma duodenale, Necator americanus, Angiostrongylus costaricensis,  an  Anisakis Ascaris  species,  Ascaris lumbricoides, Baylisascaris procyonis, Brugia malayi, Brugia timori, Dioctophyme renale, Dracunculus medinensis, Enterobius vermicularis, Enterobius gregorii, Gnathostoma spinigerum, Gnathostoma hispidum, Halicephalobus gingivali, Loa loa filarial, Mansonella streptocerca, Onchocerca volvulus, Strongyloides stercoralis, Thelazia californiensis, Thelazia callipaeda, Toxocara canis, Toxocara cati, Trichinella spiralis, Trichinella britovi, Trichinella nelsoni, Trichinella native, Trichuris trichiura, Trichuris vulpis, Wuchereria bancrofti, Archiacanthocephala, Moniliformis moniliformis, Linguatula serrate, Oestroidea, Calliphoridae, Sarcophagidae, Cochliomyia hominivorax, Tunga penetrans, Dermatobia hominis, Pediculus humanus capitis, Pediculus humanus humanus, Pthirus pubis, Demodex folliculorum/brevis/canis, Sarcoptes scabiei,  an Arachnida class member,  Trombiculidae, Pulex irritans, Cimicidae, Cimex lectularius,  an Ixodidae family member or an Argasidae family member.

Metadata:
- Claim Count in Document: 224.0
- Percentile: 88.0
- Lexical Diversity: 1.76087
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14353531', '14778454', '15483101', '14888289', '11856657']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7664541782966022
- 35 USC 102 Novelty (BERT): 0.5250413340911078
- Combined Prediction Score: 0.7423128938760528
- Mean Citation Score: 281.52684
- Max Citation Score: 339.68167
- Similarity Product: 259.7555636101139

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test