PATENT CLAIM ANALYSIS

Application Number: 16113816
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "064000"]

Abstract:
The invention relates to methods of treating cancer, with a combination of an arginase inhibitor and a chemotherapeutic agent. The invention further relates to methods of assessing efficacy of a cancer treatment by measuring arginine levels in a tumor.

Claim (Index 105):
A method of increasing the tumor-killing activity of cytotoxic T-cells in a tumor of a cancer patient, comprising administering to the patient a pharmaceutical composition that provides an effective amount of an arginase inhibitor defined in  claim 104  at a dosing regimen that restores the level of arginine in the tumor of the patient without increasing the arginine levels in the liver of the patient when levels of arginine are measured at the trough time-point of the inhibitor.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 96.0
- Lexical Diversity: 1.44828
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15190653', '15853310', '15567838', '15284865', '14394463']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7303080448517011
- 35 USC 102 Novelty (BERT): 0.5488659271540712
- Combined Prediction Score: 0.7121638330819381
- Mean Citation Score: 303.922088
- Max Citation Score: 397.9382
- Similarity Product: 285.65231108990906

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test