PATENT CLAIM ANALYSIS

Application Number: 16403034
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-08
Patent Classification: ["514", "226500"]

Abstract:
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability, solubility, or pharmacokinetics of the NSAID for the treatment of conditions such as pain.

Claim (Index 1):
A method of improving dissolution of meloxicam in a stomach of a human being, comprising orally administering a solid dosage form comprising a bicarbonate and a complex of meloxicam with a cyclodextrin to the human being, wherein the solid dosage form contains 400 mg to 800 mg of the bicarbonate, wherein, at a designated time, the dissolution of meloxicam for the solid dosage form is improved as compared with a reference dosage form that: 1) contains the same amount of meloxicam; 2) contains the same amount of cyclodextrin; and 3) does not contain the bicarbonate, wherein the rate of dissolution of meloxicam of the solid dosage form or the reference dosage form is determined by a dissolution test, wherein the dissolution test is: adding the dosage form or the reference dosage form to 500 mL of a 0.01 N HCl aqueous solution, stirring at 75 revolutions per minute (RPM) with a USP paddle apparatus II at 37\u00b0 C., and determining the amount of meloxicam dissolved in the 0.01 N HCl aqueous solution at the designated time.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 100.0
- Lexical Diversity: 1.39474
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16000701', '15984055', '16372958', '16006642', '16006692']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7601088733810805
- 35 USC 102 Novelty (BERT): 0.5455814629011531
- Combined Prediction Score: 0.7386561323330878
- Mean Citation Score: 354.77306
- Max Citation Score: 383.15268
- Similarity Product: 370.2519489669229

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test