PATENT CLAIM ANALYSIS

Application Number: 16061574
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["435", "221000"]

Abstract:
Provided is a mutant of the wild type phosphatidylcholine-specific phospholipase C of  Bacillus cereus . The mutations involved comprise the amino acid residue at position 63 being mutated from asparagine to aspartic acid, the amino acid residue at position 131 being mutated from asparagine to serine, and the amino acid residue at position 134 being mutated from asparagine to aspartic acid, and may comprise the amino acid residue at position 56 being mutated from tyrosine to alanine, lysine, asparagine, glutamine, histidine or tryptophan, and further, may also comprise the amino acid residue at position 106 being mutated from methionine to valine. Also provided are a polynucleotide molecule encoding the mutant, a nucleic acid construct and a host cell comprising the polynucleotide molecule, a composition comprising the mutant, and the use of the mutant, the polynucleotide molecule, the nucleic acid construct and the host cell.

Claim (Index 12):
The isolated polynucleotide sequence according to  claim 4 , wherein the isolated amino acid sequence is set forth in SEQ ID NO: 7 with the amino acid Xaa at position 56 of SEQ ID NO: 7 is alanine, lysine, asparagine, glutamine, histidine or tryptophan; or\n the isolated amino acid sequence is a polypeptide derived from the amino acid of SEQ ID NO:7 by substitution, deletion or addition of one or several amino acids in the amino acid sequence in SEQ ID NO:7 while retaining the phospholipase C activity of SEQ ID NO: 7, with the amino acid residue at position 56 is histidine and the amino acid residue at position 106 is valine.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 94.0
- Lexical Diversity: 2.58065
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15035105', '14902448', '10592450', '13502069', '15521654']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5997833105076166
- 35 USC 102 Novelty (BERT): 0.5480259596790451
- Combined Prediction Score: 0.5946075754247594
- Mean Citation Score: 302.533364
- Max Citation Score: 399.3739
- Similarity Product: 296.61427370018964

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test