PATENT CLAIM ANALYSIS

Application Number: 15888948
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "184100"]

Abstract:
The technology relates in part to methods for inducing partial apoptosis of cells that express an inducible caspase polypeptide. The technology further relates in part to methods for inducing partial apoptosis of cells that express an inducible modified caspase polypeptide, having a modified dose response curve to the multimeric ligand inducer. The technology also relates in part to methods for cell therapy using cells that express the inducible caspase polypeptide or the inducible modified caspase polypeptide, where the proportion of caspase polypeptide-expressing cells eliminated by apoptosis is related to the administered amount of the multimeric ligand inducer.

Claim (Index 18):
The method of  claim 2 , wherein the first subset of therapeutic cells, the second subset of therapeutic cells, or the first subset of therapeutic cells and the second subset of therapeutic cells are selected from the group consisting of hematopoietic stem cells, inducible progenitor cells (iPS), embryonic stem (ES) cells, mesenchymal stem cells (MSCs), plasma (B) cells, myocytes, natural killer (NK) cells, macrophages, tumor infiltrating lymphocytes (TILs), and T cells.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 2.21739
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14296404', '15224441', '13792135', '14743384', '13112739']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7845577925829587
- 35 USC 102 Novelty (BERT): 0.6722150057648503
- Combined Prediction Score: 0.7733235139011478
- Mean Citation Score: 666.3747679999999
- Max Citation Score: 882.8988
- Similarity Product: 626.8875463570117

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test