PATENT CLAIM ANALYSIS

Application Number: 16153273
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-03
Patent Classification: ["435", "004000"]

Abstract:
Compositions and Methods for Stabilizing Circulating Tumor Cells Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, especially blood, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.

Claim (Index 35):
The method of  claim 1 , wherein DNA present in the treated blood samples exhibits ellipticity that is substantially similar to that of untreated native DNA as measured by circular dichroism spectroscopy.

Metadata:
- Claim Count in Document: 49.0
- Percentile: 97.0
- Lexical Diversity: 1.76364
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14907167', '12553733', '12704030', '15120502', '13511536']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5955366734085566
- 35 USC 102 Novelty (BERT): 0.5676918789455592
- Combined Prediction Score: 0.5927521939622569
- Mean Citation Score: 278.433732
- Max Citation Score: 465.6651
- Similarity Product: 384.8048133944928

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test