PATENT CLAIM ANALYSIS

Application Number: 15748541
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["435", "325000"]

Abstract:
A method of generating retinal pigment epithelial (RPE) cells is disclosed. The method comprises: (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; and (c) culturing said differentiating cells in a medium comprising one or more members of the TGFβ superfamily.

Claim (Index 2):
A method of generating RPE cells comprising:\n (a) culturing human pluripotent stem cells in a human feeder cell-conditioned medium to obtain a cultured population of human pluripotent stem cells; (b) culturing said cultured population of human pluripotent stem cells in a medium comprising a differentiating agent to obtain differentiating cells; (c) culturing said differentiating cells in a medium comprising one or more members of the TGF\u03b2 superfamily to obtain RPE cells; and (d) culturing said RPE cells on an adherent surface to generate an expanded population of RPE cells.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 86.0
- Lexical Diversity: 1.95556
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14375195', '12806907', '12450943', '13510426', '15028618']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5884467457134456
- 35 USC 102 Novelty (BERT): 0.518330338974916
- Combined Prediction Score: 0.5814351050395926
- Mean Citation Score: 312.3861520000001
- Max Citation Score: 338.91287
- Similarity Product: 283.3393087999653

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test