PATENT CLAIM ANALYSIS

Application Number: 15743546
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["546", "153000"]

Abstract:
Compounds that inhibit Myeloid Cell Leukemia-1 (Mcl-1) oncoprotein, and methods of using the same, are provided for treating disease.

Claim (Index 4):
A compound comprising formula (II): wherein each R 21  and R 22  can independently represent a substituent selected from the group consisting of H and optionally substituted alkyl and aryl; A 21  is a substituent selected from the group consisting of S(\u2550O), S(\u2550O) 2 , C(\u2550O), and CH 2 ; X 21  is CH or N; each Z 21  can independently represent a substituent selected from the group consisting of H, halo, cyano, hydroxy, nitro, and optionally substituted acylsulfonamide, alkyl, alkylaryl, alkylhetaryl, alkylheterocycloalkyl, alkenyl, alkynyl, alkenyl-cycloalkyl, alkynyl-cycloalkyl, carbonyl, carboxaldehyde, carboxyl, cycloalkyl, cycloalkyl-alkenyl, cycloalkyl-heterocycloalkyl, cycloalkyl-heteroaryl, alkoxy, alkoxycarbonyl, acyl, acyloxy, amino, amido, aryl, aralkyl, ester, fluoroalkyl, heteroalkyl, heteroalkenyl, heteroalkynyl, heteroalkylaryl, heteroalkylheteroaryl, heteroalkylheterocycloalkyl, heteroalkylcycloalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl, hydroxamate, sulfanyl, sulfinyl, sulfonyl, sulfonamidyl, sulfoxyl, and sulfonate; Y 21  is a substituent selected from the group consisting of \u2014C(O)O\u2014, \u2014CONR 22 \u2014, \u2014CONR 22 \u2014SO 2 \u2014, \u2014CONR 22 O\u2014, R 23  and R 24  each can independently represent a substituent selected from the group consisting of H and optionally substituted alkyl and aryl; and R 23  and R 24  can, taken together, comprise an optionally substituted cycloalkyl or heterocycloalkyl ring; and pharmaceutically acceptable salts, solvates, hydrates, cocrystals, or prodrugs thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 86.0
- Lexical Diversity: 1.04348
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12104294', '12096393', '14763468', '13823810', '13526337']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7408173949611093
- 35 USC 102 Novelty (BERT): 0.5108448012101608
- Combined Prediction Score: 0.7178201355860144
- Mean Citation Score: 268.77087199999994
- Max Citation Score: 276.15472
- Similarity Product: 197.5432714829064

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test