PATENT CLAIM ANALYSIS

Application Number: 15751547
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["562", "030000"]

Abstract:
Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.

Claim (Index 1):
A compound of Formula IV a , IV b , IV c  or IV d : a racemic mixture thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein: R 1  is \u2014SO 3 H, or \u2014(CH 2 ) n SO 3 H; R 3  is \u2014NR a R b , wherein:\n R a  is \u2014H or optionally substituted alkyl; and \n R b  is selected from hydrogen, alkyl substituted with a carboxyl or a carboxylate, an amino acid or a dipeptide, wherein the amino acid or the dipeptide is bound to the nitrogen atom in R 3  through a carboxy group; or \n R a  and R b  are taken together to form an optionally substituted heterocyclyl; \n R z  is an amino acid or a dipeptide; \n or R 3  is \u2014C(O)\u2014NR a R b  wherein:\n R a  is \u2014H or optionally substituted alkyl; and \n R b  is selected from hydrogen, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, and optionally substituted alkyl, or; \n R a  and R b  are taken together to form an optionally substituted heterocyclyl; \n or R 3  is \u2014C(O)R z , wherein:\n R z  is selected from an amino acid or a dipeptide, wherein the amino acid or the dipeptide is bound to the carbon atom through an amino group; or optionally substituted alkyl; \n R 4  is \u2014H, \u2014CH 3 , (CH 2 ) n  OH, \u2014NH 2 , \u2014(CH 2 ) n NH 2 , \u2014C(O)NH 2 , or \u2014(CH 2 ) n C(O)NH 2 ; n is 1 or 2; A 1  is \u2014CH2\u2014, \u2014NH\u2014, or \u2014C(O)\u2014; A 2  is \u2014CH2\u2014, \u2014NH\u2014, or \u2014C(O)\u2014; and A 3  is \u2014CH2\u2014, \u2014NH\u2014, or \u2014C(O)\u2014.

Metadata:
- Claim Count in Document: 28.0
- Percentile: 88.0
- Lexical Diversity: 1.04762
- Patent Class: 562.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16320589', '14769421', '10307735', '15740462', '15312614']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7589753699236863
- 35 USC 102 Novelty (BERT): 0.5285999911812447
- Combined Prediction Score: 0.7359378320494422
- Mean Citation Score: 338.91286
- Max Citation Score: 342.17654
- Similarity Product: 281.6773779597318

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test