PATENT CLAIM ANALYSIS

Application Number: 15748767
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["435", "458000"]

Abstract:
The present invention provides a polyion complex which can efficiently deliver mRNA into a living body as well as a therapeutic agent and a therapeutic method of arthropathy in which the polyion complex is used. For example, there is provided a polyion complex comprising a cationic polymer and mRNA, wherein the cationic polymer is a polymer comprising a cationic unnatural amino acid as a monomer unit and the cationic unnatural amino acid is an amino acid having a group represented by —(NH—(CH 2 ) 2 ) p —NH 2 , wherein p is 2, 3 or 4, as a side chain.

Claim (Index 3):
The polyion complex according to  claim 1 , wherein the cationic polymer is represented by formula (I): wherein R 1  is polyethylene glycol and may be linked to an amino acid neighboring the polyethylene glycol through a linker, R 2  is methylene or ethylene, R 3  is a group represented by \u2014(NH\u2014(CH 2 ) 2 ) p \u2014NH 2 , and p is 2, 3 or 4, R 4  is hydrogen, a protecting group, a hydrophobic group, or a polymerizable group, X is a cationic natural amino acid, n is any integer from 2 to 5000, n 1  is any integer from 0 to 5000, n 3  is any integer from 0 to 5000, n\u2212n 1 \u2212n 3  is an integer equal to or greater than 0, and though the repeating units in the formula are shown in a particular order for convenience of description, the repeating units may be present in any order and the repeating units may be present at random, and each of the repeating units may be the same or different.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 1.85
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15118407', '13386554', '13386154', '13256605', '15575716']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6302519309060932
- 35 USC 102 Novelty (BERT): 0.5160618240895916
- Combined Prediction Score: 0.6188329202244431
- Mean Citation Score: 259.36306
- Max Citation Score: 326.7634
- Similarity Product: 277.2494394401312

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test