PATENT CLAIM ANALYSIS

Application Number: 15965613
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["436", "086000"]

Abstract:
A method for identifying a polypeptide a specimen can include (i) treating a specimen suspected of including an insulin with a base; (ii) extracting a first fraction of the treated specimen by solid phase extraction using a mixed mode or polymeric reversed-phase media and a first solvent including an acid; (iii) separating a component of the first fraction by liquid chromatography using a chromatographic surface including a hydrophobic surface group and one or more ionizable modifiers, and a second solvent including an acid; and (iv) analyzing the component of the first fraction by mass spectroscopy, thereby identifying the polypeptide, if present, using a signal corresponding to a sequence fragment ion from the polypeptide. The signal can correspond to an intact multiply charged precursor fragment selected in a first quadrupole and its corresponding sequence fragment ion selected in a final quadrupole.

Claim (Index 41):
The method of  claim 24 , wherein analyzing the component of the first fraction by mass spectroscopy can resolve any two or more of exenatide, hepcidin, teriparatide, enfuvirtide, calcitonin, brain natriuretic peptide (BNP), amyloid beta peptides, GLP-1, glucagon, bombesin, or a derivative or analog thereof.

Metadata:
- Claim Count in Document: 83.0
- Percentile: 91.0
- Lexical Diversity: 1.91463
- Patent Class: 436.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15447838', '14394952', '13750511', '15059247', '12989827']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7272453544298139
- 35 USC 102 Novelty (BERT): 0.6601000411081964
- Combined Prediction Score: 0.7205308230976522
- Mean Citation Score: 417.09868000000006
- Max Citation Score: 706.0735
- Similarity Product: 638.2311347579358

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test