PATENT CLAIM ANALYSIS

Application Number: 16227398
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "252020"]

Abstract:
Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.

Claim (Index 9):
A compound selected from the group consisting of\n a) compounds having a structure represented by Formula (I): wherein\n W, X, and Y are each independently O, S, NR 2  or N(R 2 ) 2 ; \n T is \u2014CONR 2 \u2014, \u2014C(NR 2 )NH\u2014, \u2014C(NOR 2 )NH\u2014, \u2014C(N\u2014NR 2 )NH\u2014, \u2014C(SR 2 )N\u2014, or \u2014NHC(O)\u2014; \n A is phenyl, heteroaryl, C5-C10 branched or unbranched cycloalkyl, C6-C10 bicycloalkyl or C5-C10 spirocycloalkyl; \n each Z is independently present or absent and, if present, is independently selected from one or more halogen atoms, \u2014CN, \u2014CF 3 , \u2014OR 2 , \u2014C(O)R 2 , SR 2 , \u2014S(O) g R 3  where g is 1 or 2, \u2014N(R 2 ) 2 , \u2014NO 2 , \u2014CO 2 R 2 , \u2014OCO 2 R 3 , OC(O)R 2 , \u2014CON(R 2 ) 2 , \u2014NR 2 C(O)R 2 , \u2014SO 2 N(R 2 ) 2 , \u2014NR 2 SO 2 R 3 , \u2014NR 2 SO 2 N(R 2 ) 2  or \u2014NR 2 C(O)N(R 2 ) 2 , \u2014C(O)NHOR 2 , alkyl, aryl, alkenyl and alkynyl; \n wherein each R 2  is independently H, alkyl or aryl; wherein each R 3  is independently alkyl or aryl, optionally substituted with one or more halogen atoms or OR 2 ; and wherein a, b, c, d, and e are each independently carbon or nitrogen, or four of a, b, c, d, and e are each independently carbon or nitrogen and one of a, b, c, d, and e is O, with the proviso that at least one of a, b, c, d and e is nitrogen, and Z is not connected directly to nitrogen or oxygen; and\n b) tautomers of any of the foregoing compounds.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 98.0
- Lexical Diversity: 2.02381
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15545429', '15118243', '14889563', '15750205', '12946759']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7985287887705899
- 35 USC 102 Novelty (BERT): 0.5630208758147699
- Combined Prediction Score: 0.774977997475008
- Mean Citation Score: 347.39679399999994
- Max Citation Score: 468.1944
- Similarity Product: 308.1463663324356

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test