PATENT CLAIM ANALYSIS

Application Number: 15894842
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["435", "366000"]

Abstract:
This disclosure provides an improved system for culturing human embryonic stem cells. The cells are cultured in suspension so as to maximize the production capacity of the culture environment. The new culture system of this invention allows for bulk proliferation of hES cells in a more cost-effective manner, which facilitates commercial production of important products for use in human therapy.

Claim (Index 21):
A method for culturing undifferentiated human pluripotent stem (hPS) cells in suspension, the method comprising:\n a) suspending undifferentiated hPS cells in a cell culture medium comprising basic fibroblast growth factor (bFGF); b) maintaining the hPS cells substantially undifferentiated while culturing in suspension; c) changing the cell culture medium periodically; and d) optionally splitting the culture from time to time, so as to reduce the density of the hPS cells in culture; wherein the hPS cells are not grown attached to a solid substrate.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 88.0
- Lexical Diversity: 1.3617
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11917993', '10235094', '12763884', '12170219', '13323567']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6432922301745314
- 35 USC 102 Novelty (BERT): 0.5548467075548168
- Combined Prediction Score: 0.63444767791256
- Mean Citation Score: 403.00106000000005
- Max Citation Score: 439.70462
- Similarity Product: 375.6432309420967

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test