PATENT CLAIM ANALYSIS

Application Number: 16068629
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["424", "133100"]

Abstract:
An embodiment of the invention relates to the use of stabilized cancer peptide fragments derived from Protocadherin FAT1 for the diagnosis of cancers, particularly pancreatic cancer. A method for the detection of cancer, severity of cancer, and/or effectiveness of a therapeutic regimen includes detecting and/or measuring the amount of Protocadherin FAT1 peptide fragments present in the biological sample of a subject.

Claim (Index 44):
A method for monitoring the progression of cancer in a subject comprising:\n determining the amount of one or more Protocadherin FAT1 peptide fragments present in the biological sample at a first time point, determining the amount of one or more Protocadherin FAT1 peptide fragments present in the biological sample at one or more subsequent time points, and comparing the amount of the one or more Protocadherin FAT1 peptide fragments present in the biological sample at the one or more subsequent time points with the amount of the one or more Protocadherin FAT1 peptide fragments present in the biological sample at the first time point, wherein a higher amount of the one or more Protocadherin FAT1 peptide fragments at the one or more subsequent time points compared to the amount of the one or more Protocadherin FAT1 peptide fragments at the first time point indicates that the cancer has progressed since the first time point, and wherein a lower amount of the one or more Protocadherin FAT1 peptide fragments at the one or more subsequent time points compared to the amount of the one or more Protocadherin FAT1 peptide fragments at the first time point indicates that the cancer has regressed since the first time point, wherein each of the one or more Protocadherin FAT1 peptide fragments has an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-11.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 95.0
- Lexical Diversity: 1.60976
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14800162', '13384014', '13464174', '14671062', '13813680']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7366570045125457
- 35 USC 102 Novelty (BERT): 0.5404645853031051
- Combined Prediction Score: 0.7170377625916017
- Mean Citation Score: 313.977452
- Max Citation Score: 393.46048
- Similarity Product: 304.58148866134644

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test