PATENT CLAIM ANALYSIS

Application Number: 16271150
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-05
Patent Classification: ["435", "455000"]

Abstract:
A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.

Claim (Index 13):
The piPSC cells according to  claim 9 , for use in human clinic applications selected from the group consisting essentially of, but not limited to, regeneration medicine and cell replacement therapy, generation of the iPS cell banks from individual patients with genetic disorders, disease models based on piPS cells from individual patients and testing of efficacy and toxicity of drugs, including, but not limited to, small molecule drugs, protein drugs, DNA drugs, RNA drugs, carbohydrate drugs, and lipid-based drugs.

Metadata:
- Claim Count in Document: 16.0
- Percentile: 99.0
- Lexical Diversity: 1.5283
- Patent Class: 435.0
- Transitional Phrase Type: half
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15808205', '14113522', '12939454', '12997815', '14117589']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.736579378942143
- 35 USC 102 Novelty (BERT): 0.6289111280252315
- Combined Prediction Score: 0.7258125538504518
- Mean Citation Score: 584.3899200000002
- Max Citation Score: 810.3085
- Similarity Product: 524.270674037248

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test