PATENT CLAIM ANALYSIS

Application Number: 16134417
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["424", "234100"]

Abstract:
Disclosed is the use of fluorinated cyclic dinucleotides and pharmaceutically acceptable salts thereof as an adjuvant for the preparation of an oral vaccine. Further disclosed is the use of fluorinated cyclic dinucleotides and pharmaceutically acceptable salts thereof for enhancing the immune response to an orally administered vaccine.

Claim (Index 6):
A method for preparing an oral vaccine, comprising admixing one or more non-replicating antigens with an adjuvant, wherein said adjuvant is a fluorinated cyclic dinucleotide having the following structure: wherein A, C, A\u2032 and C\u2032 are independently selected from NH, O or S; X, Y, X\u2032, and Y\u2032 are independently selected from O or S; Z and Z\u2032 are independently selected from O, S, NH or CH 2 ; and B 1  and B 2  are independently a purine selected from: wherein Q is hydrogen or NH 2 ; nitrogen is optionally substituted with C 1 -C 6  alkyl or C 1 -C 6  acyl group; and R is O or S.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 97.0
- Lexical Diversity: 1.68966
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15038229', '11669006', '13748412', '12092747', '15630741']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6105086960583707
- 35 USC 102 Novelty (BERT): 0.5969315163501417
- Combined Prediction Score: 0.6091509780875478
- Mean Citation Score: 311.59269
- Max Citation Score: 522.6394700000002
- Similarity Product: 432.7738339784236

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test