PATENT CLAIM ANALYSIS

Application Number: 16067490
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["544", "344000"]

Abstract:
Described are positive allosteric modulators of the GLP-1 receptor, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for diabetes mellitus type 2, obesity, depression, Alzheimer's disease, Parkinson's disease, Huntington's disease, stroke, cognitive dysfunction, learning disability, and asthma in a subject.

Claim (Index 1):
A compound of formula (I), or a pharmaceutically acceptable salt thereof; wherein W is CR 1  or N; X is CR 1  or N; Y is CR 1  or N; Z is CR 1  or N; R 1 , at each occurrence, is independently selected from the group consisting of hydrogen, alkyl, alkenyl, cycloalkyl, halogen, alkoxy, cycloalkoxy, heteroalkyl, cyano, SO 2 R a , NR b R c , C(O)NR b R c , hydroxyl, heterocycle, heteroaryl, and haloalkyl; R 2  is hydrogen, alkyl, alkenyl, cycloalkyl, halogen, alkoxy, cycloalkoxy, heteroalkyl, cyano, SO 2 R a , NR b R c , hydroxyl, heterocycle, heteroaryl or haloalkyl; R 3  is alkyl, cycloalkyl, heterocycle, aryl, heteroaryl, SO 2 R a , or haloalkyl;\n R a , at each occurrence, is independently selected from the group consisting of alkyl, cycloalkyl, heterocycle, heteroaryl, aryl, heteroalkyl, and NR b R c ; \n R b  and R c , at each occurrence, are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, heterocycle, heteroaryl, and heteroalkyl; \n L is amide, sulfonamide, heteroalkyl, alkoxy, alkoxyalkyl, alkylamino, aminoalkyl, or alkyl; n is 0, 1, 2 or 3; t is 0 or 1; R 4  and R 5  are each independently hydrogen, alkyl, or haloalkyl; and R 6  and R 7  are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, heterocycle, heteroaryl, and haloalkyl; or R 6  and R 7  together with the nitrogen atom to which they are attached form a heterocycle; or R 4  and R 6  together with the atoms to which they are attached form a heterocycle.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 97.0
- Lexical Diversity: 1.53846
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15006486', '11510451', '13469021', '12390286', '15661582']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8030990418238568
- 35 USC 102 Novelty (BERT): 0.5291741715669537
- Combined Prediction Score: 0.7757065547981665
- Mean Citation Score: 339.47541600000005
- Max Citation Score: 352.13074
- Similarity Product: 267.24408237904066

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test