PATENT CLAIM ANALYSIS

Application Number: 16127399
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-06
Patent Classification: ["530", "323000"]

Abstract:
Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R 1 -R 7 , L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.

Claim (Index 18):
A thioester compound of Formula (XXV) or a pharmaceutically acceptable salt thereof, wherein: R 1  and R 2  are independently selected from the group consisting of H, C 1 -C 10  alkyl and C 3 -C 7  cycloalkyl, or R 1  and R 2  taken together form a C 3 -C 7  cycloalkyl or C 3 -C 7  heterocycloalkyl wherein the C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl and C 3 -C 7  heterocycloalkyl are optionally substituted with one or more substituents selected from the group consisting of C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl, C 3 -C 7  heterocycloalkyl, aryl, heteroaryl, halo, hydroxyl, \u2014CN, \u2014COOH, \u2014CF 3 , \u2014OCH 2 F, \u2014OCHF 2 , \u2014OC 1 -C 10  alkyl, \u2014O-aryl, \u2014O-heteroaryl, \u2014NR 8 R 9 , \u2014NR 8 C(O)R 9 , NR 8 C(O)OR 9 , \u2014NR 8 CO 2 R 9 , and \u2014C(O)NR 8 R 9 ; R 3  and R 4  are independently selected from the group consisting of H, C 1 -C 10  alkyl and C 3 -C 7  cycloalkyl, or R 3  and R 4  taken together form a C 3 -C 7  cycloalkyl or C 3 -C 7  heterocycloalkyl wherein the C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl and C 3 -C 7  heterocycloalkyl are optionally substituted with one or more substituents selected from the group consisting of C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl, C 3 -C 7  heterocycloalkyl, aryl, heteroaryl, halo, hydroxyl, \u2014CN, \u2014COOH, \u2014CF 3 , \u2014OCH 2 F, \u2014OCHF 2 , \u2014OC 1 -C 10  alkyl, \u2014O-aryl, \u2014O-heteroaryl, \u2014NR 8 R 9 , \u2014NR 8 C(O)R 9 , NR 8 C(O)OR 9 , \u2014NR 8 CO 2 R 9 , and \u2014C(O)NR 8 R 9 ; R 5  and R 6  are independently selected from the group consisting of H, C 1 -C 10  alkyl and C 3 -C 7  cycloalkyl, or R 5  and R 6  taken together form a C 3 -C 7  cycloalkyl or C 3 -C 7  heterocycloalkyl wherein the C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl and C 3 -C 7  heterocycloalkyl are optionally substituted with one or more substituents selected from the group consisting of C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl, C 3 -C 7  heterocycloalkyl, aryl, heteroaryl, halo, hydroxyl, \u2014CN, \u2014COOH, \u2014CF 3 , \u2014OCH 2 F, \u2014OCHF 2 , \u2014OC 1 -C 10  alkyl, \u2014O-aryl, \u2014O-heteroaryl, \u2014NR 8 R 9 , \u2014NR 8 C(O)R 9 , NR 8 C(O)OR 9 , \u2014NR 8 CO 2 R 9  and \u2014C(O)NR 8 R 9 ; R 8  and R 9  are independently selected from the group consisting of H, C 1 -C 10  alkyl and C 3 -C 7  cycloalkyl, or R 8  and R 9  taken together form a C 3 -C 7  cycloalkyl or C 3 -C 7  heterocycloalkyl wherein the C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl and C 3 -C 7  heterocycloalkyl are optionally substituted with one or more substituents selected from the group consisting C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl, C 3 -C 7  heterocycloalkyl, aryl, heteroaryl, halo, hydroxyl, \u2014CN, \u2014COOH, \u2014CF 3 , \u2014OCH 2 F, \u2014OCHF 2 , \u2014OC 1 -C 10  alkyl, \u2014O-aryl, \u2014O-heteroaryl, \u2014NR 10 R 11 , \u2014NR 10 C(O)R 11 , \u2014NR 10 C(O)OR 11  and \u2014C(O)NR 10 R 11 ; R 10  and R 11  are independently selected from the group consisting of H, C 1 -C 10  alkyl and C 3 -C 7  cycloalkyl, or R 10  and R 11  taken together form a C 3 -C 7  cycloalkyl or C 3 -C 7  heterocycloalkyl; and R 13  and R 14  are independently selected from the group consisting of H, C 1 -C 10  alkyl, C 3 -C 7  cycloalkyl, C 3 -C 7  heterocycloalkyl, aryl and heteroaryl.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 97.0
- Lexical Diversity: 1.8125
- Patent Class: 530.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15313800', '13700373', '14289877', '13139009', '15700923']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6903840511968661
- 35 USC 102 Novelty (BERT): 0.5689240038083749
- Combined Prediction Score: 0.678238046458017
- Mean Citation Score: 352.377376
- Max Citation Score: 454.32477
- Similarity Product: 381.6459827798581

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test