PATENT CLAIM ANALYSIS

Application Number: 16028532
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["435", "370000"]

Abstract:
The invention relates to a method for reprogramming cells from aged donors or senescent cells to pluripotent cells that have lost marks of senescence. In particular, the invention relates to an ex vivo method for preparing induced pluripotent stein cells (iPSCs) from a target cell population comprising cells from aged donors or senescent cells, said method comprising the steps of culturing said target cell population tinder appropriate conditions for reprogramming said cells into iPSCs, wherein said appropriate conditions comprises increasing expression in said target cells, of at least the following reprogramming factors: Oct4, Klf4, Sox2, Myc, Lin28 and, optionally Nanog.

Claim (Index 19):
The method of  claim 18 , wherein said iPSCs are further differentiated into a desired cell lineage prior to said step of performing.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 95.0
- Lexical Diversity: 1.78125
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14009662', '13893166', '15261803', '14117589', '14258971']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6555614305189944
- 35 USC 102 Novelty (BERT): 0.5898891114936446
- Combined Prediction Score: 0.6489941986164595
- Mean Citation Score: 448.742578
- Max Citation Score: 639.40155
- Similarity Product: 385.9017458056837

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test