PATENT CLAIM ANALYSIS

Application Number: 15986332
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "046000"]

Abstract:
Provided is an A 3 AR ligand for reducing ectopic fat accumulation, particularly in fatty liver. Further provided is the use of A 3 AR ligand for the preparation of a pharmaceutical composition for reducing such fat accumulation, method of treating a condition associates with fat accumulation making use of the ligand and kits including pharmaceutical compositions including the ligand, and instructions for use of same, for treating a condition associated with ectopic fat accumulation. Further provided is the use of an A 3 AR agonist, such as 2-Chloro-N 6 -(3-iodobenzyl)-adenosine-5′-N-methyluronamide (Cl-IB-MECA, CF102) for treating fatty liver, specifically, non-alcoholic fatty liver disease (NAFLD).

Claim (Index 57):
A method for reducing lipid accumulation in a liver tissue of a subject having non-alcoholic fatty liver disease (NAFLD), comprising administering to said subject an amount of an A 3  adenosine receptor (A 3 AR) ligand selected from the group consisting of N 6 -2-(4-aminophenyl)ethyl adenosine (APNEA), N 6 -(4-amino-3-iodobenzyl) adenosine-5\u2032-(N-methyluronamide) (AB-MECA), N 6 -(3-iodobenzyl)-adenosine-5\u2032-N-methyluronamide (IB-MECA) and 2-chloro-N 6 -(3-iodobenzyl)-adenosine-5\u2032-N-methyluronamide (Cl-IB-MECA).

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 2.17857
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14420439', '13320715', '15160462', '11604905', '13386339']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.736055554443903
- 35 USC 102 Novelty (BERT): 0.4917801693540776
- Combined Prediction Score: 0.7116280159349205
- Mean Citation Score: 190.585484
- Max Citation Score: 222.2446
- Similarity Product: 162.31922206772566

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test