PATENT CLAIM ANALYSIS

Application Number: 16118007
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-04
Patent Classification: ["544", "280000"]

Abstract:
A compound of the Formula I and optionally a pharmaceutically acceptable salt thereof is provided: Formula I, wherein, R is one selected from the group consisting of H and CH 3 ; n is an integer ranging from 1 to 4; X is one selected from the group consisting of —CH 2 —, O, S, —NH—, —NHCHO—, —NHCOCH 3 —, and —NHCOCF 3 —; and Ar is one selected from the group consisting of (a) 1,4-phenyl, (b) 2′-fluoro-1,4-phenyl, and (c) 2,5-thienyl. Methods of treating a patient having cancer, targeting mitochondrial metabolism, and targeting SHMT2 and MTHFD2 using the compounds of this invention are disclosed.

Claim (Index 5):
A pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula II, and optionally a pharmaceutically acceptable salt thereof: Formula II, wherein, R is one selected from the group consisting of H and CH 3 ; n is an integer ranging from 1 to 4; X is one selected from the group consisting of \u2014CH 2 \u2014, O, S, \u2014NH\u2014, \u2014NHCHO\u2014, \u2014NHCOCH 3 \u2014, and \u2014NHCOCF 3 \u2014.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 96.0
- Lexical Diversity: 1.81429
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15981636', '15705200', '16103375', '15331777', '15135334']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7976074214276563
- 35 USC 102 Novelty (BERT): 0.5265884191993334
- Combined Prediction Score: 0.770505521204824
- Mean Citation Score: 350.80531999999994
- Max Citation Score: 356.7374
- Similarity Product: 245.62658080998656

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test