PATENT CLAIM ANALYSIS

Application Number: 16035300
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "136100"]

Abstract:
The present invention pertains to antigen recognizing constructs against COL6A3 antigens. The invention in particular provides novel T cell receptor (TCR) based molecules which are selective and specific for the tumor expressed antigen COL6A3. The TCR of the invention, and COL6A3 antigen binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of COL6A3 expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.

Claim (Index 16):
The method of  claim 1 , wherein the TCR comprises one of the following \u03b1 chain/\u03b2 chain pairs:\n an \u03b1 chain consisting of the amino acid sequences of SEQ ID NO: 6 and a \u03b2 chain consisting of the amino acid sequences of SEQ ID NO: 12; \n an \u03b1 chain consisting of the amino acid sequences of SEQ ID NO: 18 and a \u03b2 chain consisting of the amino acid sequences of SEQ ID NO: 24; or \n \u03b1 chain consisting of the amino acid sequences of SEQ ID NO: 30 and a \u03b2 chain consisting of the amino acid sequences of SEQ ID NO: 36.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 95.0
- Lexical Diversity: 1.77966
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15677651', '15461020', '15460654', '16023731', '14763421']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.824664041269382
- 35 USC 102 Novelty (BERT): 0.6648472663309167
- Combined Prediction Score: 0.8086823637755355
- Mean Citation Score: 587.633812
- Max Citation Score: 923.05096
- Similarity Product: 613.6170334087657

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test