PATENT CLAIM ANALYSIS

Application Number: 16103830
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "248000"]

Abstract:
Embodiments of a method and/or system can include administering, to a patient with one or more conditions associated with at least one of TMA, TMAO, and/or derivatives thereof, a therapeutically effective amount of a compound for affecting inhibiting one or more CutC enzymes and/or CntA enzymes associated with microorganisms from at least one taxon from a set of microorganism taxa.

Claim (Index 20):
A method for identifying at least one compound for treating a patient with a condition associated with at least one of trimethylamine (TMA), trimethylamine N-oxide (TMAO), and derivatives thereof, the method comprising:\n determining a representative sequence of an enzyme associated with the at least one of TMA, TMAO, and derivatives thereof, wherein the representative sequence is representative of a set of sequences of the enzyme for at least one taxon from a set of microorganism taxa; generating a protein structure model of the enzyme based on the representative sequence of the enzyme; determining a control binding parameter to the enzyme based on a control docking simulation with the protein structure model and a control molecule; determining a set of compound binding parameters to the enzyme based on a set of compound docking simulations with the protein structure model and a library of compounds; and identifying the at least one compound, from the library of compounds, for treating the patient with the condition associated with the at least one of TMA, TMAO, and derivatives thereof, based on a comparison between the control binding parameter and the set of compound binding parameters.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 96.0
- Lexical Diversity: 1.58537
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15610145', '14866398', '15366940', '15605437', '13915299']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7251985461096624
- 35 USC 102 Novelty (BERT): 0.50016209034442
- Combined Prediction Score: 0.7026949005331382
- Mean Citation Score: 177.96008600000005
- Max Citation Score: 189.16028
- Similarity Product: 114.3850351099062

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test