PATENT CLAIM ANALYSIS

Application Number: 15764464
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["424", "400000"]

Abstract:
The presently disclosed subject matter provides a solid immediate release pharmaceutical multi-particulate dosage form containing at least two different populations of particulates. In certain embodiments, the immediate release pharmaceutical dosage forms contain at least three different populations of multi-particulates. Each population of particulates is designed for a specific function to accomplish the desired combination of abuse deterrence and overdose protection.

Claim (Index 79):
A solid oral immediate release multi-particulate dosage form with abuse deterrent and enhanced overdose protection properties comprising:\n a first population of crush resistant Active Particulates comprising a therapeutically effective amount of an opioid embedded in a polymer matrix, and an acid labile functional coat comprising two functional coat layers over the polymer matrix; wherein the two functional coat layers comprise functional coat layer 1 and functional coat layer 2, and wherein functional coat layer 2 surrounds functional coat layer 1; wherein functional coat layer 1 comprises a nonionic rate-controlling polymer insoluble in physiological fluids and/or organic solvents, and at least one cationic polymer, in a ratio of 80:20, and functional coat layer 2 comprises at least one cationic polymer and, optionally, a nonionic rate-controlling polymer; and a second population of Triggering Particulates comprising an alkaline agent; wherein the enhanced overdose protection properties comprise resistance to release of the opioid from the dosage form when three or more units of the dosage form are consumed intact, such that less than about 50% of the opioid is released at 30 minutes; and wherein the presence of functional coat layer 2 further enhances the resistance to release of the opioid from the dosage form provided by functional coat layer 1.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 90.0
- Lexical Diversity: 1.33333
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15117114', '15271480', '15884745', '14790101', '15271469']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7446095504610043
- 35 USC 102 Novelty (BERT): 0.544528241213438
- Combined Prediction Score: 0.7246014195362477
- Mean Citation Score: 305.646388
- Max Citation Score: 399.10718
- Similarity Product: 355.5654731600058

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test