PATENT CLAIM ANALYSIS

Application Number: 15866899
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["544", "331000"]

Abstract:
The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where R c  is an aryl sulfonic acid

Claim (Index 11):
The process of  claim 1  wherein in step (a) the metallating agent is i-PrMgCl and LiCl and the solvent is THF, in step (c) the ketoreductase is KRED-NADH-112 and step (c) further comprises the cofactor NAD and the cofactor recycling agent is glucose dehydrogenase, in step (d) (R a ) 3 Si is tert-butyldimethylsilyl, R b  is methyl, the bases are DMAP and TEA and the non-polar aprotic solvent is DCM, in step (e) the strong base is potassium hexamethyldisilazane and the organic solvent is diglyme, and in step (g) the strong base is potassium hexamethyldisilazane and the aprotic solvent is THF.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 86.0
- Lexical Diversity: 1.16667
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14473311', '15183486', '15694124', '15345537', '12517874']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7647006565355319
- 35 USC 102 Novelty (BERT): 0.5221801669152072
- Combined Prediction Score: 0.7404486075734994
- Mean Citation Score: 316.3001220000001
- Max Citation Score: 318.93372
- Similarity Product: 243.5684489950776

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test