PATENT CLAIM ANALYSIS

Application Number: 15971688
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-11
Patent Classification: ["435", "006100"]

Abstract:
The present invention relates to a nanoplasmonic sensor based on gold nanoparticle to which an antibody or an aptamer binds, the antibody or the aptamer recognizing Aβ 1-40, , Aβ 1-42, and τ protein, which are Alzheimer's disease onset markers that are present in blood, and a multi-detection method of Alzheimer's disease using Rayleigh scattering phenomenon and colorimetric assay of the sensor. The present invention has advantages in that it is possible to perform simultaneous multiple detect with respect to various onset markers by using a simple diagnosis method using blood, and sensitivity of diagnosis is improved by using a chaotropic solvent.

Claim (Index 19):
The biosensor of  claim 10 , wherein when the one or more antibodies is A\u03b2 1-40 peptide, the chaotropic solvent is potassium thiocyanate, guanidine hydrochloride, or mixture thereof.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 93.0
- Lexical Diversity: 1.72308
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11886022', '14280919', '14004634', '13422583', '14977769']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5685665975791241
- 35 USC 102 Novelty (BERT): 0.4973317300581635
- Combined Prediction Score: 0.561443110827028
- Mean Citation Score: 210.306684
- Max Citation Score: 213.17131
- Similarity Product: 150.38172570589722

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test