PATENT CLAIM ANALYSIS

Application Number: 15900419
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["530", "324000"]

Abstract:
The invention discloses a polypeptide with improved alkaline stability, which polypeptide comprises a mutant of a B or C domain of Staphylococcus Protein A (SpA), as specified by SEQ ID NO 1 or SEQ ID NO 2, or of Protein Z, as specified by SEQ ID NO 3, wherein at least the glutamine residue at position 9 has been mutated to an amino acid other than asparagine. The invention also discloses multimers of said polypeptide, as well as separation matrices comprising the multimers or polypeptides.

Claim (Index 3):
The polypeptide of  claim 1 , wherein at least the amino acid at position 3 has been mutated to an amino acid other than asparagine, proline, or cysteine, or wherein the amino acid residue at position 3 is an alanine.

Metadata:
- Claim Count in Document: 73.0
- Percentile: 88.0
- Lexical Diversity: 1.55738
- Patent Class: 530.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14961164', '14903837', '15598685', '15282367', '14904077']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7545389582030052
- 35 USC 102 Novelty (BERT): 0.5962188854714684
- Combined Prediction Score: 0.7387069509298516
- Mean Citation Score: 493.123066
- Max Citation Score: 561.6065
- Similarity Product: 424.71305445080986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test