PATENT CLAIM ANALYSIS

Application Number: 15750128
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "412000"]

Abstract:
The disclosure provides compounds having formula (I), wherein the substituents are as defined herein. The compounds are useful for modulating the dopamine D 3  receptor and for treating conditions associated therewith, such as addictions, drug dependency, and psychiatric conditions.

Claim (Index 1):
A compound, or a pharmaceutically acceptable salt thereof, having the formula: wherein; A is a saturated 4-6 carbocyclic ring, optionally in which one or two carbon atoms is heteroatoms selected among nitrogen and oxygen; and in which the group G is linked to a carbon or nitrogen; such ring may optionally be substituted at the carbon atoms or nitrogen atom by one or more C 1-4 alkyl groups; B is a saturated 4-6 heterocyclic ring in which one or two carbon atoms is heteroatoms selected among Nitrogen or Oxygen and the linking atom is always a Nitrogen atom; such ring may be also substituted at the carbon atoms or, possibly, at the different Nitrogen atom, by one or more C 1-4 alkyl group; G is phenyl, or a 5-6 membered heteroaromatic group, which is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, hydroxyl, amino, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkanoyl, haloC 1-4 alkoxy, SF 5 , \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)OR 3 ; W is S, SO 2 , O, CHR 2 , NR 3 ; n is 0 or 1; m is 1 or 2; p is 1 or 2; z is 0 or 1; R is hydrogen, C 1-4 alkyl; C 1-4 alkoxy; R 1  is hydrogen, F, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; R 2  is hydrogen, F, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; R 3  is hydrogen, C 1-4 alkyl; R 4  is hydrogen or C 1-4 alkyl; or \u2014C(\u2550O)C 1-4 alkyl; \u2014C(\u2550O)C 1-4 alkoxyC 1-4 alkyl; \u2014C(\u2550O)cyclopropyl; R 5  is hydrogen, C 1-4 alkyl; R 6  is hydrogen, C 1-4 alkyl; R 7  is halogen, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; G 1  is phenyl or a 5-6-membered heteroaromatic group or a 8-11 membered heteroaromatic group; any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, hydroxyl, amino, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, SF 5 , \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)(O) z R 3 ; Y is phenyl or a moiety selected from the group consisting of: 5-6 membered heteroaromatic group, a 8-11 membered heteroaromatic group; a saturated mono 3-7 membered carbocyclic group or a 8-11 membered bicyclic carbocyclic group in which one or more atom carbons may be replaced by N(R 4 ) z , O, S; any of such groups may be optionally substituted by 1, 2 or 3 substituents selected from: halogen, cyano, hydroxyl, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, C 1-4 alkanoyl, \u2014C(\u2550O), \u2014NHR 4 , \u2014NR 5 R 6 , SF 5 , \u2014C(\u2550O)(O) z R 3  and \u2550O; when G 1  is a phenyl group, then G 1  and Y may be fused together to form a benzofused aromatic or heteroaromatic system which might be optionally substituted by one or two substituents selected from: halogen, cyano, hydroxy, amino C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, C 1-4 alkanoyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)OR 3 , SF 5 .

Metadata:
- Claim Count in Document: 16.0
- Percentile: 88.0
- Lexical Diversity: 1.34286
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15583679', '15272114', '13613344', '12664394', '11911035']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8507879073604019
- 35 USC 102 Novelty (BERT): 0.5464962458120843
- Combined Prediction Score: 0.8203587412055702
- Mean Citation Score: 389.650642
- Max Citation Score: 434.1038
- Similarity Product: 284.7699271992445

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test