PATENT CLAIM ANALYSIS

Application Number: 16297263
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-09
Patent Classification: ["210", "637000"]

Abstract:
The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

Claim (Index 16):
A method of harvesting a biomaterial from a bioreactor system comprising a process vessel fluidly connected to a tangential flow depth filtration (TFDF) unit having a feed/retentate channel and a filtrate channel, comprising the steps of:\n pumping a culture medium comprising the biomaterial from the process vessel through the feed/retentate channel of the TFDF unit, whereby a fraction of the biomaterial passes into the filtrate channel; returning fluid from the feed/retentate channel to the process vessel; and collecting fluid from the filtrate channel; wherein the TFDF unit comprises a thick-walled hollow fiber formed from a polymer and comprising a porous wall, the thick-walled hollow fiber having a density of about 53% of the density of an equivalent solid volume of the polymer, the porous wall defining a lumen of 3 mm to 7 mm that is in fluid communication with the feed/retentate channel, the porous wall having a thickness of about 5 mm; wherein the TFDF unit has a flux above about 400 L\u00b7m \u22122 \u00b7hr \u22121 ; wherein the TFDF unit has a peak cell passage of under 5%; wherein a rate of sieving of the bioproduct is at least 99%.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 99.0
- Lexical Diversity: 1.44828
- Patent Class: 210.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15269409', '13408243', '13983982', '10517871', '12435481']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7875617101319592
- 35 USC 102 Novelty (BERT): 0.4978164559109265
- Combined Prediction Score: 0.758587184709856
- Mean Citation Score: 217.957098
- Max Citation Score: 227.60825
- Similarity Product: 145.19382487350703

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test