PATENT CLAIM ANALYSIS

Application Number: 16137040
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "171000"]

Abstract:
The present invention provides bacterial ATP synthase inhibitors such as a compound of formula (I): There are provided compositions and kits using such compounds and inhibitors.

Claim (Index 1):
A compound of formula (I): wherein: R1 is H; and R2 is \u2014OH or \u2014NR5R6; or R1 is \u2014OH or \u2014NR5R6; and R2 is H;\n wherein R5 and R6 are identical or different and are selected from the group consisting of H; substituted or unsubstituted alkyl; substituted or unsubstituted aryl; substituted or unsubstituted aralkyl; substituted or unsubstituted cycloalkyl, and substituted or unsubstituted \u2014(CH 2 )nNR7R8,\n wherein n is 2-10; and \n R7 and R8 are identical or different and are selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl; substituted or unsubstituted cycloalkyl, and substituted or unsubstituted aralkyl; \n \n wherein the substituted alkyl(s), substituted aryl(s), substituted aralkyl(s), substituted cycloalkyl(s), and substituted \u2014(CH 2 )nNR7R8 comprise(s) one or more identical or different substitutions selected from alkyl, aryl, cycloalkyl and aralkyl; \n R3 is \u2014C(CH 3 )(NHR9),\n wherein R9 is H, substituted or unsubstituted alkyl, or substituted or unsubstituted \u2014(CH 2 )mNR11R12,\n wherein m is 2-10; and \n R11 and R12 are identical or different and are selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl, and substituted or unsubstituted aralkyl \n \n wherein the substituted alkyl(s), substituted aryl(s), substituted aralkyl(s), substituted cycloalkyl(s), and substituted \u2014(CH 2 )mNR11R12 comprise(s) one or more identical or different substitutions selected from alkyl, aryl, cycloalkyl and aralkyl; and \n R4 is H,\n with the proviso that when R3 is \u2014C(CH 3 )(NHR9), R4 is H, R1 is OH and R2 is H, R9 is substituted or unsubstituted alkyl; \n wherein the substituted alkyl comprises one or more identical or different substitutions selected from alkyl, aryl, cycloalkyl and aralkyl; or \n R3 and R4 form together with the carbon atoms to which they are attached form a spirocyclic structure of formula II: wherein R10 is H, substituted or unsubstituted alkyl, or substituted or unsubstituted \u2014(CH 2 )pNR13R14,\n wherein p is 2-10; and \n R13 and R14 are identical or different and are selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl, and substituted or unsubstituted aralkyl; \n wherein substituted alkyl, substituted aryl, substituted aralkyl, substituted cycloalkyl, and substituted \u2014(CH 2 )pNR13R14 comprises one or more identical or different substitutions selected from alkyl, aryl, cycloalkyl and aralkyl, with the proviso that when R3 and R4 form together a spirocyclic structure of formula II, neither R1 nor R2 is \u2014OH; and with the proviso that when R1 is NH2 and R2 is H; or R1 is H and R2 is NH2, R10 is not H, or a stereoisomer or mixture of stereoisomers or a salt thereof.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 97.0
- Lexical Diversity: 1.11111
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15105761', '13984991', '13980364', '13778458', '13848846']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7855249152075279
- 35 USC 102 Novelty (BERT): 0.599439495327671
- Combined Prediction Score: 0.7669163732195423
- Mean Citation Score: 327.219892
- Max Citation Score: 566.6855
- Similarity Product: 446.1660467786492

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test