PATENT CLAIM ANALYSIS

Application Number: 16087556
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-04
Patent Classification: ["514", "256000"]

Abstract:
Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof. In particular, provided in the present invention are the compound as shown in formula (I), a stereoisomer, a racemic body or a pharmaceutically acceptable salt thereof, and the use thereof in preparing drugs for preventing and treating diseases related to IDH mutation

Claim (Index 1):
A compound of formula I, a stereoisomer, a racemate or a pharmaceutically acceptable salt thereof: wherein, R 3  and R 4  are each independently selected from: H, D, substituted or unsubstituted C 1-4  alkyl; or R 3  and R 4  together with a carbon atom connecting to them form a substituted or unsubstituted C 3-6  cycloalkyl, or R 3  and R 4  together with a carbon atom connecting to them form a substituted or unsubstituted C 3-6  epoxyalkyl; R 5  and R 6  are each independently selected from: H, a substituted or unsubstituted C 1-4  alkyl, a substituted or unsubstituted C 6-10  aryl, a substituted or unsubstituted C 3-6  cycloalkyl; or R 5  and R 6  together with a carbon atom connecting to them form a substituted or unsubstituted C 3-6  cycloalkyl; R 7  and R 8  are each independently selected from: H, halogen, a substituted or unsubstituted C 1-4  alkyl; R 9  is selected from: H, a substituted or unsubstituted C 1-4  alkyl; R 10  is selected from: a substituted or unsubstituted C 1-4  alkyl; or R 9  and R 10  together with a carbon atom connecting to them form a substituted or unsubstituted C 3-6  cycloalkyl; R 11  is selected from: a substituted or unsubstituted C 6-10  aryl, a substituted or unsubstituted C 5-10  heteroaryl; wherein the C 5-10  heteroaryl contains 1-4 heteroatoms selected from N, O or S; and the term \u201csubstituted\u201d means having one or more (eg 1, 2, 3 or 4) substituents selected from Group A: the substituents of Group A are selected from the group consisting of H, D, halogen, a substituted or unsubstituted C 1-6  alkyl, a substituted or unsubstituted C 3-8  cycloalkyl, a substituted or unsubstituted C 1-4  alkoxy, a substituted or unsubstituted C 6-10  aryl, a substituted or unsubstituted C 5-10  heteroaryl, a substituted or unsubstituted C 6-10  aryloxy, \u2014C(O)NHRa; wherein Ra\u2032 is selected from: a substituted or unsubstituted C 1-6  alkyl, a substituted or unsubstituted C 3-8  cycloalkyl; R 12  is selected from: H, D, a substituted or unsubstituted C 1-4  alkyl, a substituted or unsubstituted 3-6 membered ring; for R 3 -R 12 , the term \u201csubstituted\u201d means having one or more substituents selected from Group B; the substituents of Group B are selected from the group consisting of H, D, halogen, a substituted or unsubstituted C 1-6  alkyl, \u2014OH, a substituted or unsubstituted C 1-4  alkoxy, 3-8 membered cyclic hydrocarbon group, amino, nitro; and, in the substituents of Group A and Group B, the term \u201csubstituted\u201d means having one or more (e.g., 1, 2, 3, 4 or 5) substituents selected from the group consisting of D, halogen, C 1-4  alkyl, trifluoromethyl, amino, nitro, \u2014OH.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 97.0
- Lexical Diversity: 1.75
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15575235', '14858170', '14858174', '12974622', '15568051']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7924806275315613
- 35 USC 102 Novelty (BERT): 0.5183868179211527
- Combined Prediction Score: 0.7650712465705205
- Mean Citation Score: 303.943354
- Max Citation Score: 309.93964
- Similarity Product: 251.3977153652596

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test