PATENT CLAIM ANALYSIS

Application Number: 15975423
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["424", "179100"]

Abstract:
The present disclosure relates to compounds of formula (I): RCG1-L-P  (I) wherein RCG1 represents a reactive chemical group being reactive towards a chemical group present on a polypeptide such as an antibody; P represents H, OH or an activated O; and L represents a specific linker. The disclosure also relates to cryptophycin payloads, as well as to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The disclosure also relates to the process for preparing these conjugates.

Claim (Index 17):
A conjugate of formula (V): wherein:\n R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , n, X, Y and L are as defined in formula (IV) according to  claim 14 ; \n G represents the product of reaction between RCG1 as defined in  claim 13 , a reactive chemical group present at the end of the linker L of formula (II) as defined in  claim 1 , and RCG2, an orthogonal reactive chemical group present on a polypeptide such as the antibody (Ab); and \n Ab represents an antibody.

Metadata:
- Claim Count in Document: 55.0
- Percentile: 93.0
- Lexical Diversity: 1.61667
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14069057', '15581749', '15280563', '14843520', '14818455']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7689366965088661
- 35 USC 102 Novelty (BERT): 0.5206777185644269
- Combined Prediction Score: 0.7441107987144222
- Mean Citation Score: 309.744996
- Max Citation Score: 313.26495
- Similarity Product: 211.4542370973766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test