PATENT CLAIM ANALYSIS

Application Number: 16280890
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["435", "194000"]

Abstract:
Described herein are polymerase variants that are exonuclease deficient. Some variants retain the strand displacement capability comparable to the wild-type or parental polymerase. Some variants have a strand displacement capability that is improved relative to the wild-type or parental polymerase. The variants may have an extension rate that is greater than the wild-type or parental polymerase. The variants may have a waiting time that is less than the wild-type or parental polymerase.

Claim (Index 1):
A modified DNA polymerase, derived from a parental DNA polymerase polypeptide having a DNA polymerase activity comprising an amino acid sequence having at least 80% sequence identity to the amino acid sequence as set forth in SEQ ID NO: 1, comprising a substitution at a position corresponding to a position selected from the group consisting of T45, H123, L125, W127, D128, V179, S211, Y212, I215, T216, E219, Q221, E239, D241, Y259, Q260, A292, S293, and S294 of SEQ ID NO: 2, wherein the modified polymerase is exonuclease deficient.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 99.0
- Lexical Diversity: 2.2
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15444020', '15151364', '15012317', '15443964', '15492214']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6228728145940422
- 35 USC 102 Novelty (BERT): 0.6168230591258055
- Combined Prediction Score: 0.6222678390472185
- Mean Citation Score: 451.841992
- Max Citation Score: 621.24207
- Similarity Product: 484.69854613693

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test