PATENT CLAIM ANALYSIS

Application Number: 16084979
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["544", "155000"]

Abstract:
An octahydroanthracene compound having the structure shown in formula (I) and (II), preparation method and application thereof are disclosed. The octahydroanthracene compound has a good therapeutic effect on tumors and neurodegenerative diseases. The preparation of the octahydroanthracene compound is mainly carried out by using benzene as a starting material, and being subjected to Friedel-Crafts reaction, nitration, reduction, (sulfo-) amide formation, reduction, urea formation or amide formation, thus obtaining a target compound.

Claim (Index 1):
An octahydroanthracene compound and pharmaceutically acceptable salts of the octahydroanthracene compound, wherein structural formulas of the octahydroanthracene compound and the pharmaceutically acceptable salts of the octahydroanthracene compound are shown in (I) and (II): wherein X is H or C1-C6 alkyl group; Linker is a substituted/unsubstituted C6-C10 aroyl (sulfonyl) or heteroaroyl (sulfonyl) group; wherein a substituent of the substituted. C6-C10 aroyl (sulfonyl) or heteroaroyl (sulfonyl) group is a C1-C6 alkyl group, a C1-C6 alkoxy group, a halogen, an amino group, a nitro group, a mercapto group, a thioether, a sulfone, a sulfoxide or an aminoalkoxy group; R 1  is hydrogen or C1-C6 alkyl group; R is a nitrogen- or nitrogen-free structural fragment; R 2 , R 3  are hydrogen, nitrogen- or nitrogen-free structural fragments; and wherein the nitrogen-free structural fragment is C1-C20 alkyl group; a structure of the nitrogen-structural fragment is: wherein the Linker1 of the structure of the nitrogen-structural fragment is a C2-C6 linear or branched alkyl group, and the NR 4 R 5  is a primary amine or secondary amine.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 97.0
- Lexical Diversity: 1.51724
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14291860', '14342953', '14009418', '13407520', '15527975']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7508471069759614
- 35 USC 102 Novelty (BERT): 0.5079348240697291
- Combined Prediction Score: 0.7265558786853381
- Mean Citation Score: 237.793098
- Max Citation Score: 256.24344
- Similarity Product: 182.0740232795763

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test