PATENT CLAIM ANALYSIS

Application Number: 15980165
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "649000"]

Abstract:
Disclosed are methods for the treatment of various solid tumors in patients in need of such treatment. The methods comprise administering to such a patient an NEDD8-activating enzyme (NAE) inhibitor such as ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]-pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate (MLN4924) or a pharmaceutically acceptable salt in combination with one or more chemotherapeutic agents. Also disclosed are medicaments for use in the treatment of various solid tumors.

Claim (Index 28):
A kit for treating a solid tumor in a subject in recognized need thereof comprising:\n at least one medicament comprising at least one dose of ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate or a pharmaceutically acceptable salt thereof, at least one medicament comprising at least one dose of carboplatin, and at least one medicament comprising at least one dose of paclitaxel; said kit for treating solid tumors further comprising dosing instructions for administering the medicaments for treatment of the subject in recognized need thereof.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 93.0
- Lexical Diversity: 1.5614
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13667641', '12779331', '14432587', '14354149', '15249851']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7373529703478888
- 35 USC 102 Novelty (BERT): 0.5682253678920192
- Combined Prediction Score: 0.7204402101023019
- Mean Citation Score: 334.24532000000005
- Max Citation Score: 449.59985
- Similarity Product: 361.8803423891813

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test