PATENT CLAIM ANALYSIS

Application Number: 16075110
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "293000"]

Abstract:
The present application present application relates to a compound represented by Formula (III) or a pharmaceutically acceptable salt, solvent compound, active metabolite, crystal polymorph, ester, isomer, or prodrug thereof. The application further provides a pharmaceutical composition comprising the compound represented by Formula (III) and a use thereof for preparing a bromodomain inhibitor for preventing or treating various diseases, such as inflammation and cancer, related to the bromodomain.

Claim (Index 16):
The compound or a pharmaceutically acceptable salt, solvate, active metabolite, polymorph, ester, isomer or prodrug thereof according to  claim 1 , wherein the compound is represented by the following Formula (V): wherein W 1 , W 2 , W 3  and W 4  are each independently selected from the group consisting of CH and N, and at least one of them is N; preferably, one or two of W 1 , W 2 , W 3  and W 4  are N, and the others are CH; and more preferably, one of W 1 , W 2 , W 3  and W 4  is N, and the others are CH; R 1  is selected from the group consisting of halogen, \u2014CN, \u2014OH, \u2014NH 2 , \u2014NH-optionally substituted C 1-6  alkyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)-optionally substituted C 1-6  alkyl, \u2014C(\u2550O)N(CH 3 )\u2014OCH 3 , \u2014C(\u2550O)NH-optionally substituted C 1-6  alkyl, \u2014COOH, \u2014C(\u2550O)O-optionally substituted C 1-6  alkyl, \u2014OC(\u2550O)NH-optionally substituted C 1-6  alkyl, \u2014NHOC(\u2550O)-optionally substituted C 1-6  alkyl, \u2014NHC(\u2550O)NH-optionally substituted C 1-6  alkyl, \u2014NHSO 2 NH-optionally substituted C 1-6  alkyl, optionally substituted C 1-6  alkyl, optionally substituted C 2-6  alkenyl, optionally substituted C 2-6  alkynyl, optionally substituted C 1-6  alkoxy, optionally substituted C 3-8  cycloalkyl, optionally substituted C 3-8  cycloalkyl-CO\u2014, optionally substituted C 3-8  cycloalkyl-SO 2 \u2014, optionally substituted aryl C 1-6  alkoxy, optionally substituted C 3-8  cycloalkyl-C 1-6  alkoxy, optionally substituted heterocycloalkyl-CO\u2014, optionally substituted heterocycloalkyl, optionally substituted C 1-6  alkyl-SO 2 \u2014, \u2014NHSO 2 -optionally substituted C 1-6  alkyl, \u2014N(SO 2 -optionally substituted C 1-6  alkyl) 2 , \u2014NHSO 2 -optionally substituted heterocycloalkyl, optionally substituted C 1-6  alkyl-NHSO 2 \u2014 and optionally substituted heterocycloalkyl-NHSO 2 \u2014; R 2  is selected from the group consisting of optionally substituted 6- to 10-membered aryl, optionally substituted 5- to 7-membered heteroaryl containing 1-3 heteroatoms independently selected from the group consisting of N, O and S, and 3- to 8-membered heterocycloalkyl containing 1-3 heteroatoms independently selected from the group consisting of N, O and S; m is selected from the group consisting of 0, 1, 2 and 3; and n is selected from the group consisting of 1, 2 and 3.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.65306
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15305384', '14819541', '14072563', '14207868', '14846545']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8410212136997937
- 35 USC 102 Novelty (BERT): 0.5304444084568598
- Combined Prediction Score: 0.8099635331755003
- Mean Citation Score: 362.686824
- Max Citation Score: 366.06772
- Similarity Product: 278.1603628230238

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test