PATENT CLAIM ANALYSIS

Application Number: 15979144
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-05
Patent Classification: ["435", "157000"]

Abstract:
The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.

Claim (Index 1):
A genetically modified yeast cell comprising at least six or more of the following modifications: (a) an increased expression of Mus musculus fatty acid reductase (FAR) (MmFAR1), or functional fragment thereof; (b) an increased expression of acetyl-CoA carboxylase (ACC1), or functional fragment thereof: (c) an increased expression of fatty acid synthase 1 (FAS1), or functional fragment thereof: (d) an increased expression of fatty acid synthase 2 (FAS2), or functional fragment thereof: (e) a reduced expression of or knocked out for DGA1; (f) a reduced expression of or knocked out for HFD1; (g) a reduced expression of or knocked out for ADH6; (h) an increased expression of a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, or functional fragment thereof; (i) a reduced expression of or knocked out for GDH1; and (j) an increased expression of the desaturase encoded by OLE1, or functional fragment thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.8
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15005719', '13656086', '14547304', '13704776', '15562951']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5950190718554247
- 35 USC 102 Novelty (BERT): 0.5415362208185668
- Combined Prediction Score: 0.5896707867517389
- Mean Citation Score: 363.167662
- Max Citation Score: 387.4936
- Similarity Product: 291.39933457765585

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test