PATENT CLAIM ANALYSIS

Application Number: 15903379
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["514", "021300"]

Abstract:
The present invention provides a peptide at least partially derivable from human Thyroid Stimulating Hormone Receptor (TSHR) which peptide is capable of binding to an MHC molecule in vitro and being presented to a T cell without further antigen processing. The present invention also relates to the use of such peptides for the prevention or suppression of activating autoantibody formation in Graves' Disease.

Claim (Index 2):
A peptide according to  claim 1 , which is selected from the following: (SEQ ID No 12) RNB_5D-GKK: KKGIYVSIDVTLQQLESHGKK   (SEQ ID No. 21) RNB_5D-KKK: KKKIYVSIDVILQQLESHKKK   (SEQ ID No 13) RNB_5E-GKK: KKGYVSIDVTLQQLESHSGKK   (SEQ ID No 6) RNB_5A: ISRIYVSIDVTLQQL   (SEQ ID No 7) RNB_5B: SRIYVSIDVTLQQLE   (SEQ ID No 8) RNB_5C: RIYVSIDVTLQQLES   (SEQ ID No 9) RNB_5D: IYVSIDVTLQQLESH   (SEQ ID No 10) RNB_5E: YVSIDVTLQQLESHS   (SEQ ID No 11) RNB_5F: VSIDVTLQQLESHSF   (SEQ ID No 14) RNB_5F-GKK: KKGVSIDVTLQQLESHSFGKK   (SEQ ID No 16) RNB_4J-GKK: KKGSNLPNISRIYVSIDVGKK   (SEQ ID No 15) RNB_4J: SNLPNISRIYVSIDV   (SEQ ID No. 62) RNB_4K: NLPNISRIYVSIDVT   (SEQ ID No. 63) RNB_4K-GKK: KKGNLPNISRIYVSIDVTGKK   (SEQ ID) No 18) RNB_9B: GLKMFPDLTKVYSTD   (SEQ ID No 17) RNB_9A: TGLKMFPDLTKVYST   (SEQ ID No 19) RNB_9C: LKMFPDLTKVYSTDI   (SEQ ID No 20) RNB_9D: KNIRDLTKVY STDIF   (SEQ ID No. 65) RNB_12A: LTLKLYNNGFTSVQG   (SEQ ID No. 66) RNB_12B: TLKLYNNGFTSVQGY   (SEQ ID No. 67) RNB_12B-KKK: KKK TLKLYNNGFTSVQGYKKK

Metadata:
- Claim Count in Document: 17.0
- Percentile: 88.0
- Lexical Diversity: 1.21429
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14910372', '15537577', '13320201', '13706540', '11979224']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7929825576040846
- 35 USC 102 Novelty (BERT): 0.5940835083614521
- Combined Prediction Score: 0.7730926526798214
- Mean Citation Score: 359.11758
- Max Citation Score: 627.2011
- Similarity Product: 405.5138429135561

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test