PATENT CLAIM ANALYSIS

Application Number: 15885220
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["514", "001100"]

Abstract:
The present invention relates to an antibody-drug-conjugate. From one aspect, the invention relates to an antibody-drug-conjugate comprising an antibody capable of binding to a Target, said antibody being conjugated to at least one drug selected from derivatives of dolastatin 10 and auristatins. The invention also comprises method of treatment and the use of said antibody-drug-conjugate for the treatment of cancer.

Claim (Index 56):
A method for preparing a compound according to  claim 29  where AH represents a \u2014CH2R 4b  group with R 4b  representing -A c -A a H with A a  as defined in  claim 29  and A c  representing:\n a (C 1 -C 7 )alkanediyl group, \n a \u2014(CH 2 CH 2 X 1 ) a1 (CH 2 CH 2 X 2 ) a2 (CH 2 CH 2 X 3 ) a3 (CH 2 CH 2 X 4 ) a4 CH 2 *\u2014 group wherein the CH 2  group marked with an asterisk is linked to the CH 2  group of \u2014CH 2 R 4b , \n an aryl or heterocycle group, \n an aryl-(C 1 -C 7 )alkanediyl or heterocycle-(C 1 -C 7 )alkanediyl group, said group being optionally substituted by a (C 1 -C 6 )alkyl group, the (C 1 -C 7 )alkanediyl moiety being linked to the CH 2  group of \u2014CH2R 4 b, \n comprising a reductive amination reaction between a compound of following formula (VIII): \n where R 1 , R 2  and R 3  are as defined in  claim 29 , and a compound of following formula (X 1 ):\n R 4b \u2014CHO\u2003\u2003(X 1 ) \n where R 4b  is as previously defined.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 86.0
- Lexical Diversity: 1.625
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15306404', '15306351', '15305157', '14923022', '14292289']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7976500550547639
- 35 USC 102 Novelty (BERT): 0.5729258893904731
- Combined Prediction Score: 0.7751776384883349
- Mean Citation Score: 411.62377999999984
- Max Citation Score: 613.6578
- Similarity Product: 345.85896485974786

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test