PATENT CLAIM ANALYSIS

Application Number: 15771465
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["514", "230500"]

Abstract:
The present application relates to novel heterocycle derivatives of Formula (I), to processes for preparing them, pharmaceutical compositions containing them, and their use thereof in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and/or memory deficits, as well as chronic and acute pain and other related CNS disorders.

Claim (Index 1):
A compound of Formula (I), or a pharmaceutically acceptable salt, solvate, tautomer or optical isomer, or combination thereof: wherein: R 1  is selected from the group consisting of C 1 -C 6  lower alkyl, C 1 -C 6  lower alkoxy, C 1 -C 6  lower alkyl-ester, C 1 -C 6  lower alkyl-amide, C 1 -C 6  lower alkyl-acid, C 1 -C 6  lower haloalkyl, C 1 -C 6 -lower haloalkoxy, C 1 -C 6 -lower haloalkyl-ester, cycloalkyl, heterocycloalkyl, bicycloalkyl, heterobicycloalkyl, aryl, heteroaryl, alkylene-aryl, alkylene-heteroaryl, hydroxyalkyl, hydroxycycloalkyl, hydroxy-heterocycloalkyl, alkenyl, aryl-alkenyl, heteroaryl-alkenyl, alkynyl, aryl-alkynyl, cycloalkenyl, heterocycloalkenyl, alkylene-O-alkyl, alkylene-O-cycloalkyl, alkylene-O-heterocycloalkyl, and alkylene-O-alkylene-cycloalkyl, alkylene-O-alkylene-heterocycloalkyl, each R 1  group being optionally substituted with one or more independently-selected groups R 5 ; R 2  and R 3  are each independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; or R 2  and R 3  connect to form, together with the carbon atom to which they are attached, a three to seven-membered carbocyclic or heterocyclic ring; and R 4  is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; X and Q are independently selected from CH 2 , O, NR 7 , S, SO and SO 2 ; R 5  is selected from the group consisting of hydroxy, halogen, cyano, nitro, CO 2 R 6 , CONHR 6 , CON(R 6 ) 2 , SO 2 NHR 6 , SO 2 N(R 6 ) 2 , C 1 -C 6  lower alkyl, C 1 -C 6  lower alkoxy, C 1 -C 6  lower alkyl-ester, C 1 -C 6  lower alkyl-amide, C 1 -C 6  lower alkyl-acid, C 1 -C 6  lower haloalkyl, C 1 -C 6  lower haloalkoxy, C 1 -C 6  lower haloalkyl-ester, cycloalkyl, heterocycloalkyl, bicycloalkyl, heterobicycloalkyl, aryl, heteroaryl, hydroxyalkyl, hydroxycycloalkyl, hydroxy-heterocycloalkyl, cyanoalkyl, alkenyl, alkynyl, cycloalkenyl, heterocycloalkenyl, alkylenearyl, alkyleneheteroaryl, alkylene-O-alkyl, alkylene-O-cycloalkyl, alkylene-O-heterocycloalkyl, alkylene-O-alkylene-cycloalkyl and alkylene-O-alkylene-heterocycloalkyl; and R 6  and R 7  are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl, provided that at least one of R 1 , R 2  and R 3  comprises a fluorine atom.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.36538
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11828457', '11828525', '12549745', '15771479', '12701474']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8414563562361281
- 35 USC 102 Novelty (BERT): 0.5114085047174172
- Combined Prediction Score: 0.808451571084257
- Mean Citation Score: 302.339146
- Max Citation Score: 307.1617700000001
- Similarity Product: 235.25165270164737

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test