PATENT CLAIM ANALYSIS

Application Number: 15865574
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "093210"]

Abstract:
The technology described herein relates to methods and kits for directed differentation of primordial NKX2-1+ lung progenitors along proximal differentiation pathways into functional airway epithelial cells and airway organoids (“bronchospheres”) or along distal lineage pathways using modulation of Wnt signaling. Other aspects relate cell lines, methods, assays and kits comprising airway epithelial cells, and assays for diagnosing a disease that affects swelling of the bronchospheres, and/or for assessing genetic lesions and/or drugs for treating the the disease, where the disease is cystic fibrosis. Other aspects relate to personalized medicine and methods of treatment of cystic fibrosis using the airway epithelial cells.

Claim (Index 6):
The method of  claim 1 , wherein the human iPSC are derived from a subject with a pulmonary disease or has cystic fibrosis.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 86.0
- Lexical Diversity: 1.66176
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15635975', '14371627', '14367061', '15223603', '14417273']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7906922213403448
- 35 USC 102 Novelty (BERT): 0.5350769590922907
- Combined Prediction Score: 0.7651306951155394
- Mean Citation Score: 358.088658
- Max Citation Score: 371.3459
- Similarity Product: 211.19882829777

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test