PATENT CLAIM ANALYSIS

Application Number: 15893341
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-11
Patent Classification: ["546", "193000"]

Abstract:
Compounds of formula I that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase, pharmaceutical compositions including such compounds and methods of treating diseases, conditions or disorders utilizing such compounds and compositions.

Claim (Index 6):
The compound of  claim 5  which is one of:\n 1-ethyl-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclohexyl-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-ethyl-3-[3-(6-piperidine-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclohexyl-3-[3-(6-piperidine-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclopropyl-3-[3-(6-piperidine-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclopropyl-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclopropyl-3-[3-(6-piperzin-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclohexyl-3-[3-(6-piperzin-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-ethyl-3-[3-(6-piperzin-1-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-cyclopropyl-3-{3-[6-(4-methyl-piperazin-1-yl)-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl]-phenyl}-urea; \n 1-ethyl-3-{3-[6-(4-methyl-piperazin-1-yl)-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl]-phenyl}-urea; \n 1-cyclohexyl-3-{3-[6-(4-methyl-piperazin-1-yl)-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl]-phenyl}-urea; \n 1-(2,4-difluoro-phenyl)-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-(4-chloro-2-fluoro-phenyl)-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-(2-fluoro-phenyl)-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; \n 1-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-3-p-tolyl-thiourea; \n 1-cyclohexyl-3-{3-[1-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-yl)-ethyl]-phenyl}-urea; \n 1-cyclohexyl-3-{3-[1-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-yl)-cyclopropyl]-phenyl}-urea; \n 1-(3-methyl-isoxazol-5-yl)-3-{3-[1-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-yl)-cyclopropyl]-phenyl}-urea; \n 1-(3-Methyl-isoxazol-5-yl)-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea; or \n 1-(5-methyl-pyridin-2-yl)-3-[3-(6-morpholin-4-yl-3\u2032,6\u2032-dihydro-2\u2032H-[2,4\u2032]bipyridinyl-1\u2032-ylmethyl)-phenyl]-urea.

Metadata:
- Claim Count in Document: 28.0
- Percentile: 88.0
- Lexical Diversity: 1.2963
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13780510', '11641284', '15613361', '14795466', '15698788']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7351030011027766
- 35 USC 102 Novelty (BERT): 0.5054183006015965
- Combined Prediction Score: 0.7121345310526587
- Mean Citation Score: 242.17147600000004
- Max Citation Score: 245.82295
- Similarity Product: 174.64218794951736

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test