PATENT CLAIM ANALYSIS

Application Number: 15887894
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-01
Patent Classification: ["530", "387100"]

Abstract:
Herein is reported a method for purifying cell cultivation supernatants either directly after fermentation or after one or more preliminary purification steps, such as protein A affinity chromatography. By adjusting the pH value in the acid range and subsequent incubation of the acidified solution host cell nucleic acid and host cell protein can be precipitated but the target polypeptide remains in solution. Thereafter the precipitate and therewith the contaminating host cell components can be removed by a simple physical separation step.

Claim (Index 11):
The method according to  claim 1 , wherein the removing is by a method selected from sedimentation, decantation, filtration, settlement, and centrifugation.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 88.0
- Lexical Diversity: 1.37097
- Patent Class: 530.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13651188', '15216099', '13883243', '15029682', '13261193']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6431958617480594
- 35 USC 102 Novelty (BERT): 0.5057544899680547
- Combined Prediction Score: 0.6294517245700589
- Mean Citation Score: 219.43621800000005
- Max Citation Score: 232.27753
- Similarity Product: 159.29603068707345

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test