PATENT CLAIM ANALYSIS

Application Number: 15743427
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["548", "263200"]

Abstract:
Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.

Claim (Index 1):
A compound, or pharmaceutically acceptable salt thereof, having a structure of formula (I): wherein\n R 1  is H, C 1-10 alkyl, or COR 9 ; \n R 2  is OH, C 1-10 alkoxy, NHC(O)R 9 , or NHSO 2 R 10 ; \n A and D are each independently CR 3  or N; \n E is CR 4  or N; \n each R 3  is H, halogen, C 1-10 haloalkyl, C 1-10 haloalkoxy, CN, CONHR 9 , SO 2 R 10 , or SO 2 NHR 9 ; \n R 4  is H, halogen, C 1-10 haloalkyl, or C 1-10 haloalkoxy; \n R 5 , R 6 , R 7 , and R 8  are each H, halogen, CF 3 , or OCF 3 ; \n R 9  is H, C 1-10 alkyl, or C 6-10 aryl; and \n R 10  is C 1-10 alkyl or C 6-10 aryl, \n with the proviso that (a) at least one of A, D, and E is other than N, (b) at least one R 3  is other than H, and (c) at least one of R 5 , R 6 , R 7 , and R 8  is other than H.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.19231
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13836743', '14707197', '13983747', '13984991', '15744922']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7358878057725771
- 35 USC 102 Novelty (BERT): 0.4932158121735178
- Combined Prediction Score: 0.7116206064126711
- Mean Citation Score: 218.08078
- Max Citation Score: 222.3453
- Similarity Product: 159.1924141604662

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test