PATENT CLAIM ANALYSIS

Application Number: 16373971
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["544", "268000"]

Abstract:
The invention relates to polymorphous crystal modifications of a DPP-IV inhibitor, the preparation thereof and the use thereof for preparing a medicament.

Claim (Index 2):
The method according to  claim 1  wherein polymorph C is obtained by a method comprising:\n (a) refluxing a solution of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine in methanol to provide a hot methanolic solution, \n (b) cooling the hot methanolic solution to a temperature of 40-60\u00b0 C. to provide a cooled methanolic solution, \n (c) adding tert-butylmethylether to the cooled methanolic solution to form a suspension, \n (d) cooling the suspension first to a temperature of 15-25\u00b0 C. and then to a temperature of 0-5\u00b0 C. to provide crystals, \n (e) suction filtering the crystals, and \n (f) drying the crystals obtained in step (e) in vacuo at a temperature of 70\u00b0 C. to provide Polymorph C.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 100.0
- Lexical Diversity: 1.14286
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15725426', '15285871', '14462654', '14994578', '14273753']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6672706238322904
- 35 USC 102 Novelty (BERT): 0.48725337498372
- Combined Prediction Score: 0.6492688989474334
- Mean Citation Score: 234.322804
- Max Citation Score: 269.80646
- Similarity Product: 267.7715919501889

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test