PATENT CLAIM ANALYSIS

Application Number: 15965128
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["435", "006000"]

Abstract:
The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.

Claim (Index 166):
The method of  claim 165 , wherein the microfluidic device comprises a channel having a structure that deterministically directs fetal nucleated cells in a first direction and at least some maternal cells in a second direction based on deterministic lateral displacement.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 91.0
- Lexical Diversity: 2.20635
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14930313', '13232781', '13452054', '11449149', '10529453']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7374170077858282
- 35 USC 102 Novelty (BERT): 0.5509021115644162
- Combined Prediction Score: 0.7187655181636871
- Mean Citation Score: 418.205426
- Max Citation Score: 508.741
- Similarity Product: 291.21085529124736

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test