PATENT CLAIM ANALYSIS

Application Number: 16022578
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["544", "131000"]

Abstract:
Provided herein are deuterated compounds and compositions useful in increasing PPARδ activity. The compounds have a formula where L 5  comprises at least one deuterium. Exemplary species include The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).

Claim (Index 3):
The method according to  claim 1  wherein the compound has a formula or a pharmaceutically acceptable salt thereof, wherein:\n L 1  is a bond or \u2014NR 30 \u2014; \n L 2  is \n L 3  is a bond or C 1 -C 3  alkylene; L 4 R 3  is isopropyl cyclopropyl, or R 1  is hydrogen or \u2014OR 1A ; R 1A  is hydrogen or aliphatic; each R 2  independently is selected from deuterium, heteroaryl, aliphatic, heteroaliphatic, cycloaliphatic, NO 2 , OH, amino, amide, aminosulfonyl, carboxyl, carboxyl ester, alkylsulfonyl, SO 3 H, or acyl; each R 22  independently is selected from deuterium, halogen, aryl, heteroaryl, aliphatic, heteroaliphatic, cycloaliphatic, NO 2 , OH, amino, amide, aminosulfonyl, carboxyl, carboxyl ester, alkylsulfonyl, SO 3 H, or acyl; X is O, NR 30 , sulfonyl, or S; m is from 0 to 4; and n is from 0 to 4; wherein at least one of L 3 or L 4 R 3  comprises at least one deuterium.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 94.0
- Lexical Diversity: 1.40909
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15482385', '15897796', '14874008', '15517893', '15766455']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8262784787950163
- 35 USC 102 Novelty (BERT): 0.6842708805322727
- Combined Prediction Score: 0.8120777189687419
- Mean Citation Score: 574.296458
- Max Citation Score: 707.3705
- Similarity Product: 675.8336163655819

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test