PATENT CLAIM ANALYSIS

Application Number: 15860461
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-10
Patent Classification: ["073", "061550"]

Abstract:
Methods of analyzing purity of compositions comprising cysteamine and detecting impurities in cysteamine compositions are described.

Claim (Index 28):
A method of analyzing purity of compositions comprising cysteamine comprising:\n (i) dissolving a cysteamine sample in a solvent having an acidic pH to form a sample solution comprising cysteamine; (ii) injecting the sample solution onto a C18 reverse-phase HPLC column; (iii) gradient eluting the sample from the column using first and second mobile phases, wherein the first mobile phase comprises: about 85% by volume of an aqueous solution having a pH of about 2.6, the aqueous solution comprising about 23.6 mM 1-octanesulfonic acid sodium and about 29 mM sodium phosphate; about 3% by volume of acetonitrile; and about 12% by volume of methanol, and the second mobile phase comprises: about 10% by volume of an aqueous solution having a pH of about 2.6, the aqueous solution comprising about 0.2 M 1-octanesulfonic acid sodium and about 0.1 M sodium phosphate; about 18% by volume of acetonitrile; and about 72% by volume of methanol; and (iv) measuring the eluted sample using a UV detector at a wavelength of about 210 nm or less.

Metadata:
- Claim Count in Document: 13.0
- Percentile: 86.0
- Lexical Diversity: 1.21429
- Patent Class: 73.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14306820', '14306303', '14751639', '15771947', '15238037']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6810132932350783
- 35 USC 102 Novelty (BERT): 0.6520568223786758
- Combined Prediction Score: 0.6781176461494381
- Mean Citation Score: 239.590282
- Max Citation Score: 439.5092
- Similarity Product: 426.3629173975944

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test