PATENT CLAIM ANALYSIS

Application Number: 15886221
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["562", "007000"]

Abstract:
Provided is a method for preparing L-BPA, which includes steps of: reacting N-protected (S)-4-halophenylalanine of Formula I, a boronating agent, Grignard reagent and bis(2-methylaminoethyl)ether to obtain a reaction mixture, wherein the reaction mixture comprises N-protected (S)-4-boronophenylalanine of Formula II and the R 2  group represents a protecting group; isolating the N-protected (S)-4-boronophenylalanine from the reaction mixture; and deprotecting the R 2  group of the N-protected (S)-4-boronophenylalanine to obtain L-BPA, wherein the L-BPA has a structure of Formula III.

Claim (Index 10):
The method according to  claim 1 , wherein the step of deprotecting the R 2  group of the N-protected (S)-4-boronophenylalanine to obtain L-BPA comprises:\n adding the N-protected (S)-4-borono-L-phenylalanine, water, acid solution and a third organic solvent into a reaction vessel; adjusting the pH value to 6.15-6.25 so as to obtain L-BPA.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 88.0
- Lexical Diversity: 2.01961
- Patent Class: 562.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13910233', '15122118', '10538466', '13996955', '15245935']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6833978892763495
- 35 USC 102 Novelty (BERT): 0.58724755618378
- Combined Prediction Score: 0.6737828559670925
- Mean Citation Score: 280.78857600000003
- Max Citation Score: 485.06506
- Similarity Product: 390.67279386014224

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test