PATENT CLAIM ANALYSIS

Application Number: 15772497
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-11
Patent Classification: ["544", "279000"]

Abstract:
Disclosed is a preparation method for a Palbociclib free base crystal form A as shown in Formula I, comprising the following steps: treating a Palbociclib free base and/or a Palbociclib salt compound by using an inorganic base in a water solvent at the temperature of 35 to 100° C. to obtain a Palbociclib free base crystal form A, the water solvent being water or mixed solvent obtained by water and an organic solvent capable of being mixed and disclosed in the water. Also disclosed is a preparation method for a Palbociclib free base crystal form B, comprising the following steps: treating a Palbociclib salt compound by using an inorganic base in a water solvent at the temperature of 0 to 20° C. to obtain a Palbociclib free crystal form B, the water solvent being water or a mixed solvent obtained by water and an organic solvent capable of being mixed and dissolved in the water. The method is safe and convenient in operation and low in pollution, and facilitates industrial production.

Claim (Index 9):
A preparation method for a crystal form B of palbociclib free base, the method comprising the following step: treating a palbociclib salt compound with an inorganic base in an aqueous solvent at a temperature of 0-20\u00b0 C. to obtain a crystal form B of palbociclib free base, wherein the aqueous solvent is water or a mixed solvent of water and water-miscible organic solvent.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 91.0
- Lexical Diversity: 2.82812
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16315816', '15749100', '15328795', '15613853', '13076989']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7565864077331821
- 35 USC 102 Novelty (BERT): 0.4914200520920354
- Combined Prediction Score: 0.7300697721690674
- Mean Citation Score: 220.432162
- Max Citation Score: 231.08447
- Similarity Product: 165.05984379615185

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test