PATENT CLAIM ANALYSIS

Application Number: 16005020
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "006160"]

Abstract:
Described herein are methods for the diagnosis, prognosis, and treatment of neurological conditions, e.g. Huntington's Disease, relating to the misregulation of miRNAs in such conditions.

Claim (Index 19):
An assay comprising\n (a) measuring, in a sample obtained from a subject, the level of at least one miRNA selected from the group consisting of:\n miR520f-3p, miR-135b-3p, miR-4317, miR-3928-5p, miR-8082, mir-140-5p; \n (b) administering a potential treatment for Huntington's Disease; (c) measuring, in a sample obtained from a subject, the level of the at least one miRNA selected from the group consisting of:\n miR520f-3p, miR-135b-3p, miR-4317, miR-3928-5p, miR-8082, mir-140-5p; \n (d) determining that the potential treatment is efficacious in reducing the risk of Huntington's Disease developing or progressing if the level of the at least one miRNA measured in step (c) is not increased relative to the level measured in step (a) and determining that the potential treatment is not in reducing the risk of Huntington's Disease developing or progressing if the level of the miRNA measured in step (c) is increased relative to the level measured in step (a).

Metadata:
- Claim Count in Document: 42.0
- Percentile: 94.0
- Lexical Diversity: 1.28
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15411329', '15877447', '15390110', '15318646', '14112684']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6287478038847725
- 35 USC 102 Novelty (BERT): 0.6188642314263445
- Combined Prediction Score: 0.6277594466389297
- Mean Citation Score: 426.75545
- Max Citation Score: 661.388
- Similarity Product: 501.068855963707

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test