PATENT CLAIM ANALYSIS

Application Number: 15769065
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["544", "242000"]

Abstract:
The invention relates to a salt, a hydrate or a crystalline form of an EGFR inhibitor, and use thereof. Specifically it relates to 4-[(3-chloro-4-fluorophenyl) amino]-7-methoxy-6-[3-[(1R,6S)-2,5-dioxa-8-azabicyclo [4.3.0] nonan-8-yl] propoxy]quinazoline dimethanesulfonate, hydrate and a crystalline form thereof; the invention also relates to a preparation method of the crystalline form disclosed herein, a pharmaceutical composition containing the crystalline form, and uses thereof for treating proliferative disorders.

Claim (Index 6):
The crystalline form of  claim 4  having an X-ray powder diffraction (XRPD) pattern comprising peaks expressed in degrees 2\u03b8 at 6.36\u00b0\u00b10.2\u00b0, 6.66\u00b0\u00b10.2\u00b0, 9.47\u00b0\u00b10.2\u00b0, 10.82\u00b0\u00b10.2\u00b0, 11.70\u00b0\u00b10.2\u00b0, 13.31\u00b0\u00b10.2\u00b0, 14.88\u00b0\u00b10.2\u00b0, 15.86\u00b0\u00b10.2\u00b0, 16.58\u00b0\u00b10.2\u00b0, 17.15\u00b0\u00b10.2\u00b0, 17.46\u00b0\u00b10.2\u00b0, 18.05\u00b0\u00b10.2\u00b0, 19.30\u00b0\u00b10.2\u00b0, 20.46\u00b0\u00b10.2\u00b0, 20.84\u00b0\u00b10.2\u00b0, 21.34\u00b0\u00b10.2\u00b0, 21.76\u00b0\u00b10.2\u00b0, 22.28\u00b0\u00b10.2\u00b0, 22.710\u00b10.2\u00b0, 23.16\u00b0\u00b10.2\u00b0, 24.07\u00b0\u00b10.2\u00b0, 24.39\u00b0\u00b10.2\u00b0, 25.180\u00b0\u00b10.2\u00b0, 25.46\u00b0\u00b10.2\u00b0, 26.29\u00b0\u00b10.2\u00b0, 26.78\u00b0\u00b10.2\u00b0, 27.15\u00b0\u00b10.2\u00b0, 28.01\u00b0\u00b10.2\u00b0, 28.80\u00b0\u00b10.2\u00b0, 29.77\u00b0\u00b10.2\u00b0, 30.44\u00b0\u00b10.2\u00b0, 31.06\u00b0\u00b10.2\u00b0, 32.05\u00b0\u00b10.2\u00b0, 33.01\u00b0\u00b10.2\u00b0, 33.51\u00b0\u00b10.2\u00b0, 33.84\u00b0\u00b10.2\u00b0, 34.90\u00b0\u00b10.2\u00b0, 38.03\u00b0\u00b10.2\u00b0, 38.58\u00b0\u00b10.2\u00b0 and 39.48\u00b0\u00b10.2\u00b0.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 91.0
- Lexical Diversity: 1.71154
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13003216', '15314938', '15778220', '14896992', '15539147']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7561864212209467
- 35 USC 102 Novelty (BERT): 0.4769980962199461
- Combined Prediction Score: 0.7282675887208466
- Mean Citation Score: 210.23572400000003
- Max Citation Score: 218.16515
- Similarity Product: 175.6970551475108

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test