PATENT CLAIM ANALYSIS

Application Number: 16028902
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "058000"]

Abstract:
6-deoxy-6-thioether-amino acid cyclodextrin derivative is obtained by condensing an amino acid derivative with halogenated cyclodextrin in presence of alkali. The 6-deoxy-6-thioether-amino acid cyclodextrin derivative includes 6-deoxysulfinyl-6-thioether-amino acid cyclodextrin derivative and 6-deoxysulfonyl-6-thioether-amino acid cyclodextrin derivative. Compounds provided are for reversing neuromuscular relaxation in patients and animals induced by muscular relaxants. The compounds are able to rapidly reverse and antagonize muscular relaxation induced by muscular relaxants and can be administrated in preparing a drug having an antagonist effect on muscular relaxation. The compounds have low production cost and are able to reverse and antagonize a wide rage of muscular relaxations, thus effectively broaden scope of clinical use. More importantly, the compounds have a safe dose at least doubled compared to prior arts. The compounds have a general formula (I).

Claim (Index 5):
A method for antagonizing muscular relaxation comprising administrating a drug comprising a therapeutically effective amount of the 6-deoxy-6-thioether amino acid cyclodextrin derivative having a structure of formula (I), wherein a is 0; b is 8; f is 0; R 1  is CH 2 ; R 2  is \u2014H; R 3  is an acetyl group; and M is \u2014H, NH 4  or alkali metal ion; wherein a cyclodextrin is \u03b3-cyclodextrin.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 95.0
- Lexical Diversity: 1.725
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13989794', '10603355', '10551343', '15909824', '16087065']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.739964281792124
- 35 USC 102 Novelty (BERT): 0.5449501107154792
- Combined Prediction Score: 0.7204628646844595
- Mean Citation Score: 228.849912
- Max Citation Score: 400.10513
- Similarity Product: 284.51162674153505

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test