PATENT CLAIM ANALYSIS

Application Number: 15962776
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
Embodiments of the invention provide a cell immunological assay kit used for evaluating the efficacy of a vaccine on the aspect of cell immunology and a method for storing the cell immunological assay kit. Some embodiments of the invention comprise a MHC-restricted viral antigenic peptide. Further, in some embodiments, the kit may use a vaccine research database of clinical trials and samples which are utilized in the therapeutic and conduct comprehensive testing on immune cells secrete cytokines by flow cytometry to establish a cellular immunology evaluation system. The kit may have a good storage stability and, in particular embodiments, the kit may provide a stability that maintains more than 90% of a material stored therein over a year or more.

Claim (Index 7):
The cell immunological assay kit of  claim 6 , wherein any group or groups of the HBsAg CD8 + T cells include one or more of the following amino acid sequence groups (A)-(C):\n A) a CD8+T cell epitope peptides A2 HBsAg comprising one or more of the following amino acid sequences: VLQAGFFLL(SEQ ID NO:8); FLLTRILTI (SEQ ID NO:9); FLGGTPVCL (SEQ ID NO:10); LLCLIFLLV (SEQ ID NO:11); LVLLDYQGML (SEQ ID NO:12); LLDYQGMLPV (SEQ ID NO:13); WLSLLVPFV (SEQ ID NO:14); GLSPTVWLSV (SEQ ID NO:15); SIVSPFIPLL (SEQ ID NO:16); ILSPFLPLL (SEQ ID NO:17); B) a CD8 \u2212 T cell HBV mixed phenotypic peptide comprising one or more of the following amino acid sequences: FLLTRILTI (SEQ ID NO:9); WLSLLVPFV (SEQ ID NO:14); GLSPTVWLSV (SEQ ID NO:15); LLVPFVQWFV (SEQ ID NO:18); FLPSDFFPSI (SEQ ID NO:19); FLPSDFFPSV (SEQ ID NO:20); CLTFGRETV (SEQ ID NO:21); EYLVSFGVW (SEQ ID NO:22); TPPATRPPNAPIL (SEQ ID NO:23); KYTSFPWL (SEQ ID NO:24); and C) a CD8 +  T cell non-A2 HBsAg mixed epitope peptide comprising one or more of the following amino acid sequences: IPIPSSWAF (SEQ ID NO:25); WMMWYWGPSLY (SEQ ID NO:26); ILLLCLIFLL (SEQ ID NO:27); RWMCLRRFII (SEQ ID NO:28); RFSWLSLLVPF (SEQ ID NO:29); LYNILSPFL (SEQ ID NO:30); PFLPLLPIF (SEQ ID NO:31); PFVQWFVGL (SEQ ID NO:32).

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.67532
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10206155', '15007160', '13622965', '14978329', '10532081']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7105867408463247
- 35 USC 102 Novelty (BERT): 0.5366402447213593
- Combined Prediction Score: 0.6931920912338282
- Mean Citation Score: 333.7363660000001
- Max Citation Score: 359.90454
- Similarity Product: 247.4226584676861

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test