PATENT CLAIM ANALYSIS

Application Number: 15897290
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["435", "325000"]

Abstract:
The invention relates a method for producing a stable recombinant protein, comprising growing a non-naturally occurring host cell in a culture medium to produce a recombinant protein, and making a composition comprising the recombinant protein and a polysorbate. The production of endogenous lipoprotein lipase by the host cell is reduced. The endogenous lipoprotein lipase is present in the composition in a small amount, and is capable of degrading the polysorbate. The invention also relates to the relevant host cells and compositions, and preparation thereof.

Claim (Index 1):
A non-naturally occurring host cell comprising a nucleic acid sequence encoding a recombinant protein, wherein the host cell expresses the recombinant protein, and wherein at least one copy of an endogenous gene encoding the endogenous lipoprotein lipase is knocked out from the genome of the host cell.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 88.0
- Lexical Diversity: 1.95745
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15105925', '15585570', '15036387', '13294759', '13395339']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5274188544911232
- 35 USC 102 Novelty (BERT): 0.6117856149819881
- Combined Prediction Score: 0.5358555305402097
- Mean Citation Score: 294.215142
- Max Citation Score: 577.9325
- Similarity Product: 473.0975762939452

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test