PATENT CLAIM ANALYSIS

Application Number: 15769028
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "413000"]

Abstract:
The present invention relates to novel compounds, e.g. for use as a medicament. In particular, the present invention relates to novel derivatives of certain nonsteroidal anti-inflammatory drugs, suitable as a medicament, preferably in the treatment and/or prevention of systemic diseases, autoimmune diseases, and/or inflammatory diseases, for example osteoarthritis, rheumatoid arthritis, multiple sclerosis and psoriasis. Further, the invention relates to a pharmaceutical composition comprising the novel compounds.

Claim (Index 1):
Compound according to Formula (I) wherein n is 1 or 2, L is \u2014((CH 2 ) 2 O) m \u2014(CH 2 ) 2 \u2014 wherein m is 1 to 5, and \u2014OOCR is a carboxylate oft 2-(2,3-dimethylphenyl)aminobenzoic acid (mefenamic acid), 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid (flufenamic acid), 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid (meclofenamic acid), 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid (niflumic acid), 2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid (aceclofenac), 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid (acemetacin), 2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid (diclofenac), 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid (etodolac), 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid (indometacin), 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid (ketorolac), 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid (bromfenac), (RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid (ibuprofen), (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid (dexibuprofen), (+)-(S)-2-(6-methoxynaphthalen-2-yl)propanoic acid (naproxen), (RS)-2-(3-benzoylphenyl)propanoic acid (ketoprofen), (2S)-2-[3-(benzoyl)phenyl]propanoic acid (desketoprofen), (RS)-2-(2-fluorobiphenyl-4-yl)propanoic acid (flurbiprofen), 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid (benoxaprofen), (RS)-2-(5-benzoyl-2-thienyl)propanoic acid (tiaprofenic acid), or 2-(acetoxy)benzoic acid (aspirin) or [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid (licofelone) or a pharmaceutically acceptable salt, hydrate, solvate, polymorph and/or mixtures thereof.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 91.0
- Lexical Diversity: 1.73913
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12456687', '15537280', '10617222', '12636329', '13322522']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.742162264013339
- 35 USC 102 Novelty (BERT): 0.4984292070193011
- Combined Prediction Score: 0.7177889583139352
- Mean Citation Score: 202.717752
- Max Citation Score: 209.38089
- Similarity Product: 149.47475220769462

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test