PATENT CLAIM ANALYSIS

Application Number: 15741665
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "187100"]

Abstract:
Compounds, compositions, and methods of treatment and prevention of HIV, including HIV-1 and HIV-2, Dengue, and Chikungunya infection are disclosed. The compounds are TREM-1 inhibitors. Combinations of these TREM-1 inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, JAK inhibitors, macrophage depleting agents, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of HIV, Dengue, or Chikungunya virus in an infected patient.

Claim (Index 16):
The method of  claim 15 , further comprising the administration of a JAK inhibitor selected from the group consisting of or a pharmaceutically acceptable salt or prodrug thereof.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 1.76923
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14360905', '14808860', '13706293', '14278394', '12739704']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.755954853066934
- 35 USC 102 Novelty (BERT): 0.5604958627813925
- Combined Prediction Score: 0.7364089540383799
- Mean Citation Score: 358.68743000000006
- Max Citation Score: 447.6391
- Similarity Product: 370.78133388434645

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test