PATENT CLAIM ANALYSIS

Application Number: 16418794
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-09
Patent Classification: ["424", "093200"]

Abstract:
The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel paratransgenic system configured to deliver one or more inhibitory RNA molecules to pathogen/disease-transmitting organisms. In a preferred embodiment, the invention may include one or more genetically engineered enteric bacteria configured to deliver one or more interfering RNA molecules to pathogen/disease-transmitting mosquitos.

Claim (Index 141):
A system for the control of an arbovirus-carrying mosquito comprising the steps of:\n identifying a mosquito symbiotic bacteria on which mosquito or mosquito larva feed, that persists in at least two of the following: the mosquito's midgut, the mosquito's gut epithelial cells, the mosquito's ovaries, the mosquito's rectum, an egg laid by a female mosquito, the chorion of eggs laid by a female mosquito, salivary glands, fat bodies, malpighian tubules and haemolymph; genetically modified the mosquito symbiotic bacteria to include an expression control sequence operably linked to at least one heterologous nucleotide encoding at least one inhibitory RNA polynucleotide that downregulates expression of at least one arbovirus gene; incorporating said genetically modified mosquito symbiotic bacteria into a mosquito ingestible feed; and introducing the mosquito ingestible feed to the mosquito such that it receives an effective amount of the genetically modified symbiotic bacteria that colonizes the mosquito and expresses the at least one inhibitory RNA polynucleotide.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 100.0
- Lexical Diversity: 1.65
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15922904', '15709890', '15601446', '15507332', '13545604']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6046105972544098
- 35 USC 102 Novelty (BERT): 0.6456774090540208
- Combined Prediction Score: 0.608717278434371
- Mean Citation Score: 351.70745
- Max Citation Score: 761.12585
- Similarity Product: 553.1613347850055

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test