PATENT CLAIM ANALYSIS

Application Number: 16060250
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["544", "278000"]

Abstract:
The present invention relates to a novel dihydropyranopyrimidinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Claim (Index 3):
The compound according to  claim 1 , wherein the compound of Chemical Formula 1 is selected from a group consisting of\n 1) 2-(4-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 2) 2-(4-(2,6-difluoro-4-(2-morpholinoethoxy)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 3) 2-(4-(2,6-difluoro-4-(2-(piperidin-1-yl)ethoxy)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 4) 2-(4-(2,6-difluoro-4-(2-hydroxyethoxy)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 5) 2-(4-(4-(2,3-dihydroxypropoxy)-2,6-difluorophenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 6) 2-(4-(2,6-difluoro-4-((4-methylpiperazin-1-yl)methyl)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 7) 2-(4-(2,6-difluoro-4-(1-hydroxyethyl)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 8) 2-(4-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-4-hydroxypiperidin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 9) 2-(4-(2-methyl-2H-tetrazol-5-yl)piperidin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 10) 2-(4-(2,6-difluoro-4-(2-oxo-2-(piperidin-1-yl)ethoxy)phenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one; 11) 2-(4-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)piperidin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 12) 2-(4-(4-(2-(diethylamino)ethoxy)-2,6-difluorophenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, 13) 2-(4-(4-(2-(1H-imidazol-1-yl)ethoxy)-2,6-difluorophenyl)piperazin-1-yl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 94.0
- Lexical Diversity: 1.32432
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15325651', '15325692', '14154161', '14154173', '14154170']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8087070271956949
- 35 USC 102 Novelty (BERT): 0.5547737898194431
- Combined Prediction Score: 0.7833137034580697
- Mean Citation Score: 369.913976
- Max Citation Score: 422.80225
- Similarity Product: 354.8557765437364

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test