PATENT CLAIM ANALYSIS

Application Number: 15887158
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["506", "009000"]

Abstract:
The invention relates to a process for parallel high throughput sequencing of nucleic acid molecules, in particular in the single molecule format.

Claim (Index 5):
The process of  claim 1 , wherein the process comprises the following steps:\n (a) providing at least one nucleic acid-synthesizing enzyme molecule immobilized on a support, a circular nucleic acid template molecule, a primer annealed to said template or capable of annealing to said nucleic acid template molecule, and fluorescence-labelled nucleotide building blocks, (b) generating a nucleic acid molecule complementary to the sequence of the circular nucleic acid template having incorporated said nucleotide building blocks in a primer elongation catalyzed by said immobilized nucleic acid-synthesizing enzyme molecule, (c) contacting said generated nucleic acid molecule with a nucleic acid-degrading enzyme molecule and cleaving off individual nucleotide building blocks from said generated nucleic acid molecule in a nuclease digestion catalyzed by said nucleic acid-degrading enzyme molecule, and (d) determining the base sequence of said circular nucleic acid template molecule on the basis of the time-dependent fluorescence change, caused when nucleotide building blocks are incorporated during primer elongation and/or cleaved off during nuclease digestion.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 88.0
- Lexical Diversity: 1.04348
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['11628400', '11336122', '10499547', '09572530', '11925607']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6119423992394106
- 35 USC 102 Novelty (BERT): 0.527685158378945
- Combined Prediction Score: 0.6035166751533642
- Mean Citation Score: 285.764626
- Max Citation Score: 333.07855
- Similarity Product: 276.419912109232

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test