PATENT CLAIM ANALYSIS

Application Number: 16232435
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-05
Patent Classification: ["435", "091100"]

Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form  m7 Gppp[N 2′Ome ] n [N] m  wherein  m7 G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Claim (Index 17):
A complex comprising an initiating capped oligonucleotide primer and a DNA template,\n wherein the initiating capped oligonucleotide primer comprises a structure: wherein B 1 , B 2 , and B 3  are independently a natural, a modified, or an unnatural nucleoside base; and R 1 , R 2 , R 3  and R 4  are independently OH or O-methyl; wherein the DNA template comprises a promoter region comprising a transcriptional start site having a first nucleotide at nucleotide position +1, a second nucleotide at nucleotide position +2, and a third nucleotide at nucleotide position +3; and wherein the initiating capped oligonucleotide primer is hybridized to the DNA template at least at nucleotide positions +1, +2, and +3.

Metadata:
- Claim Count in Document: 33.0
- Percentile: 98.0
- Lexical Diversity: 1.46154
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12375527', '13324724', '14666805', '12771495', '14471649']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5674384958346219
- 35 USC 102 Novelty (BERT): 0.5140183317217103
- Combined Prediction Score: 0.5620964794233309
- Mean Citation Score: 276.35362999999995
- Max Citation Score: 286.32123
- Similarity Product: 202.7593089481116

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test