PATENT CLAIM ANALYSIS

Application Number: 15894414
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["514", "307000"]

Abstract:
A tau aggregation inhibitor reduces tau aggregation in cells. The tau aggregation inhibitor can include a catechol structure-containing compound or a salt thereof, and the catechol structure-containing compound can be one of isoprenaline, dopamine, dobutamine, levodopa, levodopa/carbidopa, trimetoquinol, hexoprenaline, methyldopa, and droxidopa. One example of the catechol structure-containing compound is isoprenaline, which can be d-enantiomer of isoprenaline or d/l-racemic mixture of isoprenaline. Tauopathies to be prevented or treated by the inhibitor include AD, Down's syndrome, Pick's disease, corticobasal degeneration, and progressive supranuclear palsy.

Claim (Index 1):
A method of reduction of occurrence and/or treatment of a tauopathy in a subject in need thereof, comprising administering to the subject a tau aggregation inhibitor, which comprises a catechol structure-containing compound or a salt thereof, and the catechol structure-containing compound is selected from the group consisting of dopamine, levodopa, levodopa/carbidopa, methyldopa, and droxidopa, wherein the tauopathy is selected from the group consisting of Down's syndrome, corticobasal degeneration (CBD), and progressive supranuclear palsy (PSP).

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 1.83929
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13225148', '11693375', '14833679', '15645442', '15646865']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7128015016315996
- 35 USC 102 Novelty (BERT): 0.5112064773182432
- Combined Prediction Score: 0.692641999200264
- Mean Citation Score: 200.170232
- Max Citation Score: 203.33415
- Similarity Product: 109.87585388623772

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test