PATENT CLAIM ANALYSIS

Application Number: 15990030
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "233500"]

Abstract:
The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to methods of diagnosing cancer in a subject and identifying cancer therapeutics.

Claim (Index 16):
A high-throughput method of identifying a therapeutic for an oncogene-mediated cancer, said method comprising:\n providing a population of cells having enhanced macropinocytosis; providing a macropinocytosis marker; contacting the population of cells with a candidate compound under conditions effective for the candidate compound to inhibit macropinocytosis; and detecting and comparing the uptake of the macropinocytosis marker in the presence and in the absence of the candidate compound, wherein a decrease in marker uptake in the presence of the candidate compound compared to in the absence of the candidate compound identifies a therapeutic for oncogene-mediated cancer, wherein the oncogene-mediated cancer is selected from the group consisting of ras-mediated cancer, src-mediated cancer, and EGFR-mediated cancer.

Metadata:
- Claim Count in Document: 28.0
- Percentile: 93.0
- Lexical Diversity: 1.65385
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14009013', '13259533', '13873799', '14239503', '15321684']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7222765464261258
- 35 USC 102 Novelty (BERT): 0.5917977310294094
- Combined Prediction Score: 0.7092286648864542
- Mean Citation Score: 270.50412800000004
- Max Citation Score: 537.4201
- Similarity Product: 420.11811745330687

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test