PATENT CLAIM ANALYSIS

Application Number: 15867385
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["800", "298000"]

Abstract:
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences. Various methods of employing the meganuclease sequences are provided. Such methods include, for example, methods for producing a meganuclease with increased activity at a wide range of temperatures, methods for producing a yeast, plant, plant cell, explant or seed comprising a meganuclease with increased activity.

Claim (Index 20):
A method for producing a meganuclease having an increased meganuclease activity when compared to a control meganuclease, the method comprising:\n a) producing a variant meganuclease by modifying at least one amino acid at an amino acid position corresponding to a position of SEQ ID NO: 283 selected from the group consisting of positions 16, 19, 22, 50, 54, 56, 81, 103, 121, 132, 153, 244, 258, 281, 308, 316, 319, and combinations thereof; and, b) screening said variant for increased meganuclease activity when compared to a control meganuclease; and c) selecting a variant meganuclease screened in step b) that is able to cleave a DNA target sequence over said temperature range.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 86.0
- Lexical Diversity: 2.0
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15289993', '13886317', '14775777', '13532190', '13245650']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6876623926060591
- 35 USC 102 Novelty (BERT): 0.6678939100717907
- Combined Prediction Score: 0.6856855443526323
- Mean Citation Score: 499.44014
- Max Citation Score: 719.41254
- Similarity Product: 662.4590158044255

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test