PATENT CLAIM ANALYSIS

Application Number: 16359267
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["424", "190100"]

Abstract:
In one aspect, the invention relates to an immunogenic composition that includes a mutant  Clostridium difficile  toxin A and/or a mutant  Clostridium difficile  toxin B. Each mutant toxin includes a glucosyltransferase domain having at least one mutation and a cysteine protease domain having at least one mutation, relative to the corresponding wild-type  C. difficile  toxin. The mutant toxins may further include at least one amino acid that is chemically crosslinked. In another aspect, the invention relates to antibodies or binding fragments thereof that binds to said immunogenic compositions. In further aspects, the invention relates to isolated nucleotide sequences that encode any of the foregoing, and methods of use of any of the foregoing compositions.

Claim (Index 17):
The composition according to  claim 1  wherein the composition further comprises Tris buffer.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 99.0
- Lexical Diversity: 1.90769
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13970048', '14796741', '13451631', '13848909', '14529147']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7882149957694545
- 35 USC 102 Novelty (BERT): 0.5883392883022099
- Combined Prediction Score: 0.7682274250227301
- Mean Citation Score: 551.0017839999998
- Max Citation Score: 563.45605
- Similarity Product: 386.13985250260833

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test