PATENT CLAIM ANALYSIS

Application Number: 16125341
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "449000"]

Abstract:
Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of taxane-based compounds and/or fluorinated forms thereof. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the taxane-based compound is achieved.

Claim (Index 23):
A conjugate having a structure encompassed by the formula: wherein:\n each n is a positive integer from 10 to about 400; \n each L 1  is \u2014(CH 2 ) 0-6 C(\u2550O)\u2014; \n each L 3  is \u2014[NH(CHR 5 ) 1-6 C(\u2550O)] 1-4 \u2014, wherein each R 5  is independently selected from the group consisting of H and lower alkyl; \n each R 1  is selected from the group consisting of H, a hydroxy protecting group and \n and each of D 1 , D 2  and D 3  is independently selected from the group consisting of H, F, D and CF 3 ;\n each R 2  is selected from the group consisting of H, a hydroxy protecting group and \n and (a) is either zero or one and each of D 4 , D 5  and D 6  is independently selected from the group consisting of H, F, D and CF 3 ;\n each R 3  is \n and each of D 7 , D 8 , D 9 , D 10 , D 11 , D 12 , D 13 , D 14  and D 15  is independently selected from the group consisting of H, F, D and CF 3 ; and\n q is a positive integer from 3 to about 50, \n and pharmaceutically acceptable salts and solvates thereof, with the proviso that when each R 1  and R 2  are H, R 3  is with at least one of D 7 , D 8 , D 9 , D 10 , D 11 , D 12 , D 13 , D 14  and D 15  is F, D or CF 3 .

Metadata:
- Claim Count in Document: 28.0
- Percentile: 97.0
- Lexical Diversity: 1.35135
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15045077', '13433100', '14223572', '12361427', '15510345']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7276575513671334
- 35 USC 102 Novelty (BERT): 0.5113117934544631
- Combined Prediction Score: 0.7060229755758664
- Mean Citation Score: 232.760714
- Max Citation Score: 252.43303
- Similarity Product: 171.1671916311777

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test