PATENT CLAIM ANALYSIS

Application Number: 16014878
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-05
Patent Classification: ["435", "007100"]

Abstract:
The present invention relates to a piezoelectric mechanical system (PEMS) microcantilever sensor that both detects the presence of viral RNA in an aqueous solution, such as a blood sample. The method provides for the formation of the sensor by attaching RNA, DNA, or an antibody to the microcantilever sensor surface via a hydrazone or an oxime chemical bond. The method provides for the detection of viral RNA viruses and viral DNA viruses upon the chemical binding/bonding of single-stranded viral nucleic acid to the microcantilever sensor surface. The method provides for the detection of DNA cancer mutations or variants that have been identified in a cancer cell upon the chemical binding/bonding of single-stranded DNA to the microcantilever sensor surface.

Claim (Index 15):
The method of  claim 9 , wherein the antibody is bound to the surface of the piezoelectric microcantilever sensor by at least one oxime bond, wherein the oxime bond is formed between a nitrogen atom on the surface of the piezoelectric microcantilever sensor and the one or more aldehyde functional groups or the one or more ketone functional groups on the surface of the antibody; wherein the surface of the piezoelectric microcantilever sensor includes one or more alkoxyamine functional groups.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 94.0
- Lexical Diversity: 2.04839
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12514941', '14551710', '11946534', '13160304', '12900160']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6026650370929852
- 35 USC 102 Novelty (BERT): 0.4962182132647668
- Combined Prediction Score: 0.5920203547101633
- Mean Citation Score: 210.6505
- Max Citation Score: 230.83936
- Similarity Product: 159.3239437137985

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test