PATENT CLAIM ANALYSIS

Application Number: 15768037
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["546", "255000"]

Abstract:
The present invention provides a production method of heterocyclic compound having an excellent CH24H inhibitory action, which is suitable for industrial production. In the present invention, a 2-halogenonicotinic acid or a reactive derivative thereof or a salt thereof is reacted with 4-benzyl-4-hydroxypiperidine acid addition salt to give a (4-benzyl-4-hydroxypiperidin-1-yl) (2-halogenopyridin-3-yl)methanone or a salt thereof, and then the obtained compound is reacted with pyridine-4-boronic acid or a reactive derivative thereof or a salt thereof in the presence of a metal catalyst and a base to give (4-benzyl-4-hydroxypiperidin-1-yl) (2,4′-bipyridin-3-yl)methanone or a salt thereof.

Claim (Index 1):
A method of producing a (4-benzyl-4-hydroxypiperidin-1-yl) (2-halogenopyridin-3-yl)methanone or a salt thereof, which comprises reacting a 2-halogenonicotinic acid or a reactive derivative thereof or a salt thereof and a 4-benzyl-4-hydroxypiperidine acid addition salt.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 91.0
- Lexical Diversity: 2.0
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13633995', '13944042', '13944000', '15221761', '15424075']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7740970640708895
- 35 USC 102 Novelty (BERT): 0.5059600926629234
- Combined Prediction Score: 0.747283366930093
- Mean Citation Score: 272.294488
- Max Citation Score: 280.4712
- Similarity Product: 232.68338119955064

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test