PATENT CLAIM ANALYSIS

Application Number: 16437354
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-10
Patent Classification: ["435", "190000"]

Abstract:
The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine.

Claim (Index 1):
An engineered polynucleotide encoding an engineered polypeptide capable of converting 1-(3-hydroxyphenyl)-2-(methylamino)ethanone to (R)-phenylephrine, wherein the amino acid sequence of the engineered polypeptide has at least 70% identity to SEQ ID NO: 4 and comprises the residue difference C190G and at least one further residue difference at a position of SEQ ID NO: 4 selected from a position corresponding to position 2, 11, 64, 76, 95, 99, 148, 152, 153, 159, 197, 200, 202, 206, and 249.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 100.0
- Lexical Diversity: 1.125
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14755056', '15812628', '13390677', '15211990', '16126044']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6890022576832315
- 35 USC 102 Novelty (BERT): 0.6088977667409783
- Combined Prediction Score: 0.6809918085890062
- Mean Citation Score: 430.119264
- Max Citation Score: 547.5374
- Similarity Product: 478.9158914316058

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test