PATENT CLAIM ANALYSIS

Application Number: 15971250
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-02
Patent Classification: ["424", "135100"]

Abstract:
The present invention relates to monoclonal antibodies binding to human lectin-like oxidized LDL (low density lipoprotein) receptor 1 (hereinafter, sometimes referred to as “LOX-1”), and pharmaceutical compositions and methods of treatment comprising the same.

Claim (Index 28):
A nucleic acid encoding an antibody or antigen binding fragment thereof which specifically binds to human lectin-type oxidized low density lipoprotein receptor 1 (LOX-1), wherein said antibody or fragment comprises a heavy chain variable region (VH) comprising complementarity determining regions HCDR1, HCDR2, and HCDR3, and a light chain variable region (VL) comprising complementarity determining regions LCDR1, LCDR2, and LCDR3, and wherein the HCDR1 comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 8, 28, 48, 68, and 88; the HCDR2 comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 9, 29, 49, 69, and 89; the HCDR3 comprises an amino acid sequence selected from the group consisting of 10, 30, 50, 70, and 90; the LCDR1 comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 18, 38, 58, 78, and 98; the LCDR2 comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 19, 39, 59, 79, and 99; and the LCDR3 comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 20, 40, 60, 80, and 100.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 93.0
- Lexical Diversity: 1.16216
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14307515', '14307519', '15346026', '15390067', '15233026']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7702849542167296
- 35 USC 102 Novelty (BERT): 0.6128812821786097
- Combined Prediction Score: 0.7545445870129177
- Mean Citation Score: 503.60958
- Max Citation Score: 530.95294
- Similarity Product: 519.3401040252329

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test