PATENT CLAIM ANALYSIS

Application Number: 16006340
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["702", "019000"]

Abstract:
Techniques for determining therapy scores for at least two of an anti-PD1 therapy, an anti-CTLA4 therapy, an IL-2 therapy, an IFN alpha therapy, an anti-cancer vaccine therapy, an anti-angiogenic therapy, and an anti-CD20 therapy. The techniques include determining, using sequencing data for the subject and information indicating distribution of biomarker values across one or more reference populations, a first set of normalized biomarker scores for a first set of biomarkers associated with a first therapy; and a second set of normalized biomarker scores for a second set of biomarkers associated with a second therapy; providing the first set of normalized biomarker scores as input to a statistical model to obtain a first therapy score for the first therapy; and providing the second set of normalized biomarker scores as input to the statistical model to obtain a second therapy score for the second therapy.

Claim (Index 30):
The method of  claim 29 , wherein determining the first normalized score comprises:\n determining an un-normalized score for the first biomarker using the sequencing data; determining a Z-score based on the first distribution of values for the first biomarker; and determining a normalized score for the first biomarker based on the un-normalized score and the Z-score.

Metadata:
- Claim Count in Document: 54.0
- Percentile: 94.0
- Lexical Diversity: 2.68966
- Patent Class: 702.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16006279', '16006572', '16006555', '15213243', '14855229']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2311686575493041
- 35 USC 102 Novelty (BERT): 0.591576569778521
- Combined Prediction Score: 0.2672094487722258
- Mean Citation Score: 344.76700199999993
- Max Citation Score: 613.7887
- Similarity Product: 403.572160863769

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test