PATENT CLAIM ANALYSIS

Application Number: 15912295
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-07
Patent Classification: ["514", "020800"]

Abstract:
The invention provides a protein composition derived from silk fibroin, which composition possesses enhanced solubility and stability in aqueous solutions. The primary amino acid sequence of native fibroin is modified in the SDP such that cysteine disulfide bonds between the fibroin heavy and fibroin light protein chains are reduced or eliminated. Additionally, the composition can have a serine content that is reduced by greater than 40% compared to native fibroin protein, and the average molecular weight of the SDP is less than about 100 kDa.

Claim (Index 19):
A protein composition prepared by a process comprising heating an aqueous fibroin solution at an elevated pressure,\n wherein the aqueous fibroin solution comprises lithium bromide at a concentration of at least 8M, and wherein the aqueous fibroin solution is heated to at least about 105\u00b0 C. (221\u00b0 F.) under a pressure of at least about 10 PSI for at least about 20 minutes; to provide the protein composition, wherein the protein composition comprises less than 8.5% serine amino acid residues and the protein composition has an aqueous viscosity of less than 5 cP as a 10% w/w solution in water.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 1.46032
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14831473', '15212086', '14877907', '14876799', '14877904']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7639067968424883
- 35 USC 102 Novelty (BERT): 0.6526097646076681
- Combined Prediction Score: 0.7527770936190062
- Mean Citation Score: 436.771778
- Max Citation Score: 674.20886
- Similarity Product: 574.5101772473001

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test