PATENT CLAIM ANALYSIS

Application Number: 16208696
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["548", "251000"]

Abstract:
The present invention relates to a process for preparing amorphous form of Sacubitril/Valsartan sodium salt of Formula-II and pharmaceutical composition comprising thereof.

Claim (Index 4):
A stable amorphous form of Sacubitril/Valsartan sodium salt at 30\u00b15% RH prepared by a process comprising the steps of:\n i) reacting sacubitril of Formula-III, with valsartan of Formula-IV in a solvent, wherein solvent is selected from alcohol, ester, ketone and/or mixture thereof; ii) adding sodium source to the above solution, wherein sodium source is selected from Sodium hydroxide, Sodium alkoxide and Sodium 2-ethylhexanoate; iii) removing the solvent; iv) adding an organic solvent, wherein organic solvent is selected from alcohol, ester, hydrocarbon solvent and/or mixture thereof; v) removing the solvent; vi) isolating the amorphous form of Sacubitril/Valsartan sodium salt of Formula-II, and vii) optionally purifying the compound obtained in step vi).

Metadata:
- Claim Count in Document: 3.0
- Percentile: 98.0
- Lexical Diversity: 1.04545
- Patent Class: 548.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15752943', '15568550', '16046531', '15735717', '16060297']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7036349712911237
- 35 USC 102 Novelty (BERT): 0.5417267595242748
- Combined Prediction Score: 0.6874441501144388
- Mean Citation Score: 292.73433
- Max Citation Score: 377.18597
- Similarity Product: 363.0051111983324

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test