PATENT CLAIM ANALYSIS

Application Number: 15883100
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["530", "324000"]

Abstract:
The current invention discloses methods to modify protein and peptide and antigen to treat disease such as pathogen infection, autoimmune diseases and cancer. The method involves increasing the molecular weight of the protein by connecting multiple peptide units with site specific conjugation to extend the in vivo half life. The current invention also discloses methods to construct activatable enzyme, which becomes active when they reach the treatment target, therefore provide higher specificity for treatment. The current invention also relates to methods to treat disease with hemopurification.

Claim (Index 1):
A device for treating cytokine storm related syndrome comprising a container which contains and retains adsorbent that can remove soluble IL-6 receptor and IL-6,\n wherein said adsorbent comprises affinity ligand for soluble IL-6 receptor and affinity ligand for IL-6 immobilized on solid phase support medium. wherein said solid phase support medium is sufficiently porous to allow passage of blood cells or plasma therethrough, and wherein said container has an inlet and an outlet positioned with respect to the adsorbent such that blood or blood component entering the inlet contacts the adsorbent before exiting the container through the outlet.

Metadata:
- Claim Count in Document: 12.0
- Percentile: 86.0
- Lexical Diversity: 1.52459
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15124058', '12759801', '12228859', '15232714', '14997827']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5997252555266913
- 35 USC 102 Novelty (BERT): 0.5003561443695298
- Combined Prediction Score: 0.5897883444109753
- Mean Citation Score: 179.019792
- Max Citation Score: 186.83347
- Similarity Product: 108.5182130003226

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test