PATENT CLAIM ANALYSIS

Application Number: 16030854
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["514", "721000"]

Abstract:
The present invention relates to a composition for preventing or reducing microbial growth, particularly the growth of dermatophytic fungi, and/or aciduric and acidogenic gram-positive bacteria. More particularly, it relates to the use of trans-3,5,4′-trihydroxybibenzyl, also known as dihydro-resveratrol, or its dihydrostilbene derivatives and/or chemical variants as an anti-microbial agent. The present invention further relates to the management of dermatophytosis often caused by dermatophytic fungi and the management of dental caries often mediated by aciduric and acidogenic gram-positive  Streptococci . The present invention therefore has applications in preventing, alleviating and/or treating dermatophytosis and dental caries.

Claim (Index 1):
An anti-microbial agent comprising compound of formula (3): wherein\n R 2 , R 4 , and R 8  are each independently selected from \u2014OR 11 , \u2014OCH 2 R 11 , \u2014OC(O)R 11 , \u2014OCH 2 C(O)OR 11  and \u2014OC(O)CH 2 R 11 ; \n R 1 , R 3 , R 5 , R 6 , R 7 , R 9  and R 10  are each independently selected from hydrogen, halogen, trifluoromethyl, \u2014OR 11  and \u2014OC(O)R 11 ; or R 2  and R 3 , or R 7  and R 8  are taken together with the carbon atoms to which they are attached to form a cyclic group; \n R 11  is independently hydrogen, or selected from hydrocarbyl or heterocyclyl which is optionally substituted with 1, 2, 3, 4 or 5 R 12 ; \n R 12  is independently selected from halogen, trifluoromethyl, cyano, nitro, oxo, \u2014C(O)R 14 , \u2014C(O)N(R 13 )R 14 , \u2014C(O)OR 13 , \u2014OC(O)R 14 , \u2014S(O) 2 R 13 , \u2014S(O) 2 N(R 13 )R 14 , or \u2014N(R 13 )R 14 ; \n R 13  and R 14  are each independently hydrogen, or selected from hydrocarbyl or heterocyclyl which is optionally substituted with 1, 2, 3, 4 or 5 substituents independently selected from halogen, cyano, amino, hydroxy, C 1-6  alkyl or C 1-6  alkoxy; \n or an enantiomer thereof; \n or a pharmaceutically acceptable salt or prodrug thereof; \n or a mixture, derivative and/or chemical variants thereof.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 95.0
- Lexical Diversity: 1.77586
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15922919', '15352903', '15351636', '15633780', '15849650']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7886175048711661
- 35 USC 102 Novelty (BERT): 0.5723333003614605
- Combined Prediction Score: 0.7669890844201955
- Mean Citation Score: 435.760156
- Max Citation Score: 470.83017
- Similarity Product: 371.06448627416086

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test