PATENT CLAIM ANALYSIS

Application Number: 16415655
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-10
Patent Classification: ["424", "134100"]

Abstract:
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Claim (Index 1):
A method of eliciting an immune response in a patient who has cancer, comprising administering to the patient a composition comprising a population of activated T cells that kill the cancer cells that present a peptide consisting of the amino acid sequence selected from SEQ ID NOs: 86, 66, 52, 71, 31, 95, 1-8, 11-30, 32-51, 53-61, 63, 64, 67-70, 72-85, 87-94, 96-152, 155-298, 300-489, and 491-522,\n wherein said cancer is selected from the group consisting of glioblastoma, breast cancer, colorectal cancer, renal cell carcinoma, chronic lymphocytic leukemia, hepatocellular carcinoma, non-small cell and small cell lung cancer, non-Hodgkin lymphoma, acute myeloid leukemia, ovarian cancer, pancreatic cancer, prostate cancer, esophageal cancer, gallbladder cancer and cholangiocarcinoma, melanoma, gastric cancer, testis cancer, urinary bladder cancer, head and neck squamous cell carcinoma, and uterine cancer.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 100.0
- Lexical Diversity: 1.61972
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16415671', '15375070', '16109451', '16109427', '16109406']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.804900361550881
- 35 USC 102 Novelty (BERT): 0.5840026351637472
- Combined Prediction Score: 0.7828105889121676
- Mean Citation Score: 497.401334
- Max Citation Score: 499.5942
- Similarity Product: 427.56130875742434

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test