PATENT CLAIM ANALYSIS

Application Number: 16309080
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "210160"]

Abstract:
Fused aromatic bicyclic substituted 5-(2-amino-4-pyrimidinyl)-cyanoindoline derivatives (I) useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-KB-inducing kinase (NIK—also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.

Claim (Index 7):
The compound according to  claim 6 , wherein\n R 1  represents C 1-4 alkyl; R 2  represents C 1-6 alkyl substituted with one R 5 ; R 5  represents \u2014OR 7 ; R 7  represents hydrogen; R 3  represents a fused bicyclic ring system of formula (2a-1): ring A represents pyrazolyl optionally substituted with one substituent selected from the group consisting of C 1-4 alkyl, and \u2014C 1-4 alkyl-O\u2014C 1-4 alkyl; ring B represents a C 5-7 cycloalkyl or a 5- to 7-membered saturated heterocyclyl containing one or two heteroatoms each independently selected from O and N; wherein said C 5-7 cycloalkyl or 5- to 7-membered saturated heterocyclyl may optionally be substituted on one ring carbon atom with one or two C 1-4 alkyl substituents, or one ring carbon atom may optionally be substituted with oxo; and wherein said 5- to 7-membered saturated heterocyclyl may optionally be substituted on one or two ring N-atoms with a C 1-6 alkyl substituent.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 98.0
- Lexical Diversity: 1.75439
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15024603', '15766887', '15520342', '15755475', '13321158']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7977644413873425
- 35 USC 102 Novelty (BERT): 0.537535710418914
- Combined Prediction Score: 0.7717415682904997
- Mean Citation Score: 341.545594
- Max Citation Score: 364.57202
- Similarity Product: 293.812494215653

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test