PATENT CLAIM ANALYSIS

Application Number: 16420385
Application Type: Utility
Filing Date: 2019-05
Publication Date: 2019-09
Patent Classification: ["435", "007920"]

Abstract:
The present disclosure relates to a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method involves measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Further envisaged is a method of monitoring diastolic function in a patient suffering from heart failure. Also encompassed by the present disclosure are kits and devices adapted to carry out the method of the present invention.

Claim (Index 2):
The method of  claim 1 , wherein a decrease of the level of IGFBP7 and, optionally, of the at least one further biomarker in the second sample from the patient as compared to the first sample is indicative of improvement of diastolic function and/or improvement of the at least one parameter of diastolic function, and/or wherein increase of the level of IGFBP7 and, optionally of the at least one further biomarker in the second sample from the patient as compared to the first sample is indicative of deterioration of diastolic function and/or of deterioration of the at least one parameter of diastolic function.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 100.0
- Lexical Diversity: 1.66667
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15274533', '15581587', '14818768', '15220555', '12309803']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5624126183294678
- 35 USC 102 Novelty (BERT): 0.6286952643221717
- Combined Prediction Score: 0.5690408829287382
- Mean Citation Score: 325.089296
- Max Citation Score: 634.2080000000002
- Similarity Product: 505.18248748779314

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test