PATENT CLAIM ANALYSIS

Application Number: 16113816
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "064000"]

Abstract:
The invention relates to methods of treating cancer, with a combination of an arginase inhibitor and a chemotherapeutic agent. The invention further relates to methods of assessing efficacy of a cancer treatment by measuring arginine levels in a tumor.

Claim (Index 104):
The method of  claim 102 , wherein\n R\u2032\u2033 is selected from \u2014C(O)(C 1 -C 6 )alkyl, \u2014C(O)(C 3 -C 14 )aryl, \u2014C(O)O(C 1 -C 6 )alkyl, \u2014(C)O(C 3 -C 14 )aryl, \u2014C(O)(C 3 -C 14 )heterocycloalkyl and \u2014C(O)(C 3 -C 14 )aryl; wherein any alkyl, aryl, or heterocycloalkyl is optionally substituted with one or more members selected from halogen, oxo, \u2014COOH, \u2014CN, \u2014NO 2 , \u2014OH, \u2014NR d R e , \u2014NR g S(O) 2 R h , (C 1 -C 6 )alkoxy, (C 3 -C 14 )aryl, (C 1 -C 6 )haloalkyl and (C 3 -C 14 )aryloxy; and wherein R d , R e , R g , and R h  are each independently selected from H, straight or branched (C 1 -C 6 )alkyl, (C 3 -C 14 )aryl(C 1 -C 6 )alkylene-, (C 3 -C 14 )aryl, (C 1 -C 6 )hydroxyalkyl, (C 1 -C 6 )aminoalkyl, H 2 N(C 1 -C 6 )alkylene-, (C 3 -C 6 )cycloalkyl, (C 3 -C 14 )heterocycloalkyl, (C 3 -C 14 )heteroaryl, (C 3 -C 14 )aryl-(C 1 -C 6 )alkylene-, NR\u2032R\u2033C(O)\u2014, and (C 3 -C 6 )aryl-(C 3 -C 14 )-cycloalkylene-.

Metadata:
- Claim Count in Document: 3.0
- Percentile: 96.0
- Lexical Diversity: 1.44828
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15190653', '15853310', '15567838', '15284865', '14394463']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7536770514079818
- 35 USC 102 Novelty (BERT): 0.5501481477406868
- Combined Prediction Score: 0.7333241610412523
- Mean Citation Score: 303.922088
- Max Citation Score: 397.9382
- Similarity Product: 265.9131274637222

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test