PATENT CLAIM ANALYSIS

Application Number: 15871750
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["436", "501000"]

Abstract:
A method of detecting urinary calculi in a subject. Detecting urinary calculi includes first exposing the urine sample to at least one labeled binding probe that is specific to calcium/magnesium-based urinary calculi and second detecting urinary calculi bound to the at least one labeled binding probe. Methods for measuring, monitoring and/or determining subtype of urinary stone composition in a subject are also provided.

Claim (Index 11):
The method of  claim 7 , wherein the method is for monitoring a therapeutic treatment to reduce or eliminate urinary calculi in the subject, wherein the method for monitoring the therapeutic treatment comprises: (a) measuring the amount of urinary calculi in a first urine sample obtained from the subject at a first time point, the measuring comprising:\n i) exposing the first urinary sample to at least one labeled binding probe that is specific to calcium/magnesium-containing urinary calculi; and ii) measuring the amount of urinary calculi bound to the at least one labeled binding probe; (b) measuring the amount of urinary calculi in a second urine sample obtained from the subject at a subsequent time point, the measuring comprising: i) exposing the second urine sample to at least one labeled binding probe that is specific to calcium/magnesium-containing urinary calculi; and ii) measuring the amount of urinary calculi bound to the at least one labeled binding probe in the second urine sample; (c) comparing the measured urine calculi bound to the at least one labeled binding probe in the second urine sample with the measurement obtained in step (a) (ii); and (d) detecting increased or reduced urinary calculi in the subject when there is a difference in the measurement obtained in step (a) (ii) relative to the measurement obtained in step (b) (ii), thereby monitoring therapeutic treatment based on said difference.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 86.0
- Lexical Diversity: 1.52273
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14780210', '13001094', '15496822', '14439657', '11144437']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6791809432586062
- 35 USC 102 Novelty (BERT): 0.5049392346117272
- Combined Prediction Score: 0.6617567723939184
- Mean Citation Score: 254.7414
- Max Citation Score: 309.05826
- Similarity Product: 215.79314967739464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test