PATENT CLAIM ANALYSIS

Application Number: 15861017
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "259000"]

Abstract:
A method of treating a pediatric cancer in a subject in need thereof. The method includes administering to the subject a therapeutically effective amount of (S)—N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, or a pharmaceutically acceptable salt thereof, or a combination thereof.

Claim (Index 30):
The method of  claim 29 , wherein the one or more point mutations in the gene is one or more of (i) a TrkA point mutation selected from the group consisting of C6773T, C7232T, C7301T, R33W, A336E, A337T, R324Q, R324W, V420M, R444Q, R444W, G517R, G517V, K538A, V573M, F589L, G595R, G667C, F598L, R649W, R649L, R682S, V683G, R702C, Q627X, Q597X, and Q633X; (ii) a TrkB point mutation selected from the group consisting of A13T, E142K, R136H, V619M, F633L, G639R, G709C, G709A, and G709S; and/or (iii) a TrkC point mutation selected from the group consisting of V603M, F617L, G623R, G696C, G696A, and G696S.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 86.0
- Lexical Diversity: 1.5122
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15622388', '15622544', '15399207', '15706062', '15785228']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8340798500962913
- 35 USC 102 Novelty (BERT): 0.6253250940682653
- Combined Prediction Score: 0.8132043744934887
- Mean Citation Score: 432.988974
- Max Citation Score: 603.2879
- Similarity Product: 509.70295915595887

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test