PATENT CLAIM ANALYSIS

Application Number: 16096716
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["546", "326000"]

Abstract:
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.

Claim (Index 1):
A compound of Formula I wherein: R 1  is selected from hydrogen, C 1-6 alkyl, or C 3-7 cycloalkyl; R 2  is tetrahydroisoquinolinyl substituted with one R 6  substituent and also with 0-3 halo or C 1-6 alkyl substituents; R 3  is selected from azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from cyano, halo, C 1-6 alkyl, haloC 1-6 alkyl, C 1-6 alkoxy, and haloC 1-6 alkoxy; R 4  is selected from C 1-6 alkyl, haloC 1-6 alkyl; R 5  is C 1-6 alkyl; R 6  is selected from C 1-6 alkyl, C 3-7 cycloalkyl, (C 3-7 cycloalkyl)C 1-6 alkyl; (Ar 1 )C 1-6 alkyl; ([1-3.1-3.0-2]bicycloalkyl)C 1-6 alkyl, ([1-3.1-3.0-2]bicycloalkenyl)C 1-6 alkyl, or (tetrahydropyranyl)C 1-6 alkyl, and is substituted with 0-3 C 1-6 alkyl substituents; and Ar 1  is selected from pyrrolyl, furanyl, thienyl, pyrazolyl, isoxazolyl, isothiazolyl, imidazolyl, oxazolyl, thiazolyl, tetrazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, dihydropyridinonyl or phenyl and is substituted with 0-3 substituents selected from cyano, halo, C 1-6 alkyl, haloC 1-6 alkyl, C 1-6 alkoxy, and haloC 1-6 alkoxy; or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 97.0
- Lexical Diversity: 1.21875
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16094536', '15749189', '15749133', '15579977', '15749584']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7920842671036895
- 35 USC 102 Novelty (BERT): 0.5372518182152031
- Combined Prediction Score: 0.7666010222148408
- Mean Citation Score: 344.35842999999994
- Max Citation Score: 368.31903
- Similarity Product: 357.1065086220092

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test