PATENT CLAIM ANALYSIS

Application Number: 15942673
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["435", "440000"]

Abstract:
The invention is directed to a system comprising a lentivirus vector particle which encodes at least one guide RNA sequence that is complementary to a first DNA sequence in a host cell genome, a Cas9 protein, and optionally a donor nucleic acid molecule comprising a second DNA sequence. The invention also is directed to a method of altering a DNA sequence in a host cell using such a system, where the host cell can be in a human and the altered DNA can be of the human β-globin gene. The invention also is directed to a fusion protein comprising a Cas9 protein and a cyclophilin A (CypA) protein. The invention also is directed to sequences of vectors that can be used in the system and method.

Claim (Index 2):
The system of  claim 1 , which comprises a donor nucleic acid molecule comprising a second DNA sequence.

Metadata:
- Claim Count in Document: 40.0
- Percentile: 91.0
- Lexical Diversity: 2.21311
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15119867', '15179912', '14226274', '14216655', '15045368']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4907641393324428
- 35 USC 102 Novelty (BERT): 0.5310424004904263
- Combined Prediction Score: 0.4947919654482411
- Mean Citation Score: 327.507506
- Max Citation Score: 343.0626
- Similarity Product: 235.68448893932103

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test