PATENT CLAIM ANALYSIS

Application Number: 16155729
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["435", "006120"]

Abstract:
Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

Claim (Index 1):
A method for improved single molecule sequencing, the method comprising:\n preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to the set of target nucleic acid sequences, wherein each tagged nucleic acid molecule of the set of tagged nucleic acid molecules comprises:\n a UMI region comprising a set of random \u201cN\u201d bases, wherein each random \u201cN\u201d base is selected from any one of an \u201cA\u201d base, a \u201cG\u201d base, a \u201cT\u201d base, and a \u201cC\u201d base; and \n a target region corresponding to a target nucleic acid sequence of the set of target nucleic acid sequences; and \n facilitating single molecule sequencing with the set of tagged nucleic acid molecules, wherein performing the single molecule sequencing comprises:\n determining a comparison between a first set of sequence regions and a second set of sequence regions, wherein the first set of sequence regions comprises a first UMI region and a first target region of a sequenced tagged nucleic acid molecule of the set of tagged nucleic acid molecules, and wherein the second set of sequence regions comprises a second UMI region and a second target region of a tagged nucleic acid molecule of the set of tagged nucleic acid molecules; and \n stopping sequencing of the tagged nucleic acid molecule based on the comparison between the first set of sequence regions and the second set of sequence regions.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 97.0
- Lexical Diversity: 2.42553
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14947988', '15811544', '15372279', '14273197', '13852887']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5444375006457779
- 35 USC 102 Novelty (BERT): 0.4796587266004607
- Combined Prediction Score: 0.5379596232412461
- Mean Citation Score: 188.086466
- Max Citation Score: 196.9117
- Similarity Product: 145.95937324064968

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test