PATENT CLAIM ANALYSIS

Application Number: 15892343
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["514", "061000"]

Abstract:
Muparfostat for use in reducing intrahepatic tumor recurrence and increasing disease-free survival period in a hepatocellular carcinoma patient with microvascular invasion after curative liver resection, while excluding HCC patients with no vascular invasion and HCC patients with macrovascular invasion, is disclosed. The hepatocellular carcinoma patient with microvascular invasion is identified by examining a resected liver tumor sample from the HCC patient for the presence of microvascular invasion in the sample.

Claim (Index 14):
A method for treating a hepatocellular carcinoma (HCC) patient after liver resection, comprising:\n administering a therapeutically effective amount of muparfostat to the HCC patient after the liver resection, wherein the HCC patient has below characteristics: (a) a sign of microvascular invasion; and (b) at least one of the following features:\n (i) no more than one single tumor prior to the liver resection: \n (ii) having a postoperative Child-Pugh total score of lower than 8; \n (iii) having a hepatic tumor with a size of smaller than or no greater than 10 cm prior to the liver resection; and \n (iv) having a well differentiated, or moderately differentiated, or poorly differentiated tumor prior to the liver resection according to a four-tier scale of neoplastic grading.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 88.0
- Lexical Diversity: 1.64444
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14439967', '11630170', '12999907', '12513219', '12095604']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7079044377155662
- 35 USC 102 Novelty (BERT): 0.5095233032952116
- Combined Prediction Score: 0.6880663242735308
- Mean Citation Score: 224.068758
- Max Citation Score: 236.64314
- Similarity Product: 153.35771769420504

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test