PATENT CLAIM ANALYSIS

Application Number: 16000969
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["544", "277000"]

Abstract:
Provided herein are Aminopurine compounds of Formula I: or pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein R 1 , R 2 , and R 3  are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing animal and human protozoal infections.

Claim (Index 1):
A method for the treatment or prevention of trypanosomosis, trypanosomiasis, or leishmaniasis, the method comprising administering to a subject having trypanosomosis, trypanosomiasis, or leishmaniasis an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, tautomer, isotopologue, or stereoisomer thereof, wherein: R 1  is CR 1a R 1b R 1c , wherein each of R 1a , R 1b  and R 1c  is independently (C 1-4 )alkyl, or (C 1-4 )alkyl(OR); or R 1a  and R 1b  and the carbon to which they are attached form a 3-6 membered cycloalkyl or 3-6 membered heterocyclyl, and R 1c  is (C 1-4 )alkyl; R 2  is cycloalkyl or aryl, substituted with at least one NR 2 , OR, CN, NRC(O)R, CH 2 OR, CH 2 NR 2 , CH 2 NRCOR, CH 2 NRCOOR\u2032, or heterocyclylalkyl; R 3  is phenyl or pyridyl, optionally substituted with at least one halogen, CN, (C 1-2 )alkyl, or O(C 1-2 )alkyl, wherein the alkyl is optionally fluorinated; R is H or (C 1-4 ) alkyl; and R\u2032 is (C 1-4 )alkyl.

Metadata:
- Claim Count in Document: 95.0
- Percentile: 94.0
- Lexical Diversity: 1.43902
- Patent Class: 544.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15611061', '15611108', '16000968', '15335619', '14874513']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.786936229039011
- 35 USC 102 Novelty (BERT): 0.6351786835767681
- Combined Prediction Score: 0.7717604744927867
- Mean Citation Score: 476.6811080000001
- Max Citation Score: 714.4842
- Similarity Product: 528.1170775206327

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test