PATENT CLAIM ANALYSIS

Application Number: 15957686
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "001000"]

Abstract:
Disclosed herein are embodiments of a method for using estrogenic compounds to manipulate the bacterial composition of vaginal communities of female subjects. The method may include titrating a dose of an estrogenic compound to provide a female subject with a personalized effective dose, such as a minimum effective dose, sufficient to attain and/or maintain one or more determined target values of a relative abundance of vaginal  Lactobacillus  in the vaginal microbiota, an absolute abundance of vaginal  Lactobacillus  in the vaginal microbiota, a vaginal pH, a vaginal lactic acid concentration, or any combination thereof.

Claim (Index 5):
The method of  claim 4 , where adjusting, based at least in part on the subsequent analysis results, the effective dose of the estrogenic compound further comprises:\n comparing one or more of (i) the relative abundance of  Lactobacillus  in the subsequent vaginal microbiota to the determined target value of the  Lactobacillus  relative abundance, (ii) the absolute abundance of  Lactobacillus  in the subsequent vaginal community to the determined target value of the  Lactobacillus  absolute abundance, (iii) the subsequent vaginal pH to the determined target value of the vaginal pH, or (iv) the subsequent vaginal lactic acid concentration to the determined target value of the vaginal lactic acid concentration to provide a comparison; adjusting the effective dose of the estrogenic compound based on the comparison.

Metadata:
- Claim Count in Document: 47.0
- Percentile: 91.0
- Lexical Diversity: 1.68333
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15536297', '11331856', '15155675', '15740807', '14496737']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7404022006123779
- 35 USC 102 Novelty (BERT): 0.5014033892795393
- Combined Prediction Score: 0.716502319479094
- Mean Citation Score: 232.489466
- Max Citation Score: 243.5908
- Similarity Product: 190.06664682564733

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test