PATENT CLAIM ANALYSIS

Application Number: 16294864
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "006000"]

Abstract:
Methods of detecting multiple nucleic acid targets in single cells through indirect capture of labels to the nucleic acids are provided. Methods of assaying the relative levels of nucleic acid targets through normalization to levels of reference nucleic acids are also provided. Methods of detecting individual cells, particularly rare cells from large heterogeneous cell populations, through detection of nucleic acids are described. Related compositions, systems, and kits are also provided.

Claim (Index 112):
The method of  claim 98 , wherein the label probe system comprises:\n (A) the two or more identical label probe complexes each comprising the nucleic acid component and the one or more labels, wherein the nucleic acid component of the label probe complexes comprises one or more label probes capable of hybridizing to the two or more different capture probes of the sets of capture probes of the capture probe system; (B) the two or more identical label probe complexes each comprising the nucleic acid component and the one or more labels, wherein the nucleic acid component of the label probe complexes comprises one or more label probes and an amplifier capable of hybridizing to the one or more label probes and to the two or more different capture probes of the sets of capture probes of the capture probe system; or (C) the two or more identical label probe complexes each comprising the nucleic acid component and the one or more labels, wherein the nucleic acid component of the label probe complexes comprises one or more label probes, one or more amplifiers capable of hybridizing to the one or more label probes, and a preamplifier capable of hybridizing to the one or more amplifiers and to the two or more different capture probes of the sets of capture probes of the capture probe system.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 99.0
- Lexical Diversity: 1.85714
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13278353', '14151716', '11431092', '11543752', '14105080']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6746925841813962
- 35 USC 102 Novelty (BERT): 0.5143309024580114
- Combined Prediction Score: 0.6586564160090578
- Mean Citation Score: 304.67635200000007
- Max Citation Score: 320.12885
- Similarity Product: 269.0047572250366

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test