PATENT CLAIM ANALYSIS

Application Number: 15981768
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "007940"]

Abstract:
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect Chitinase-3-like protein 1 as a predictive biomarker in renal injuries.

Claim (Index 1):
A method for evaluating renal status in a subject, comprising:\n performing an assay on a urine sample obtained from the subject, wherein the assay is configured to detect Chitinase-3-like protein 1 in the urine sample, by introducing the urine sample into an assay instrument that (i) contacts all or a portion of the urine sample with a binding reagent which specifically binds for detection Chitinase-3-like protein 1, and (ii) generates an assay result indicative of binding of Chitinase-3-like protein 1 to the binding reagent; correlating the assay result to the renal status of the subject by using the assay result to a likelihood of to assign the subject to a predetermined subpopulation of individuals having a known predisposition of future acute renal failure (ARF) within 24 hours of the time at which the body fluid sample was obtained from the subject; and, treating the subject based on the predetermined subpopulation of individuals to which the patient is assigned, wherein the treatment comprises performing renal replacement therapy on the subject.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 93.0
- Lexical Diversity: 1.34091
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14241005', '15284197', '13508363', '13389351', '14524031']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6158051090949292
- 35 USC 102 Novelty (BERT): 0.5459975093656059
- Combined Prediction Score: 0.6088243491219969
- Mean Citation Score: 411.32774
- Max Citation Score: 417.94504
- Similarity Product: 339.0490332607269

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test