PATENT CLAIM ANALYSIS

Application Number: 16047805
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-05
Patent Classification: ["514", "365000"]

Abstract:
Provided herein are methods of cancer treatment by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named ITE or one of its structural analogs to a patient with cancer, for example, prostate, liver, lung, ovarian, breast, skin, colon (or rectum), stomach, pancreatic, kidney, bladder, soft tissue, or cervical cancer.

Claim (Index 2):
The method of  claim 1 , wherein the ITE structural analog has the following structural formula: wherein X and Y, independently, can be either O (oxygen) or S (sulfur); R N  can be selected from hydrogen, halo, cyano, formyl, alkyl, haloalkyl, alkenyl, alkynyl, alkanoyl, haloalkanoyl, or a nitrogen protective group; R 1 , R 2 , R 3 , R 4 , and R 5  can be independently selected from hydrogen, halo, hydroxy (\u2014OH), thiol (\u2014SH), cyano (\u2014CN), formyl (\u2014CHO), alkyl, haloalkyl, alkenyl, alkynyl, amino, nitro (\u2014NO 2 ), alkoxy, haloalkoxy, thioalkoxy, alkanoyl, haloalkanoyl, or carbonyloxy; R 6  and R 7 , can be independently selected from hydrogen, halo, hydroxy, thiol, cyano, formyl, alkyl, haloalkyl, alkenyl, alkynyl, amino, nitro, alkoxy, haloalkoxy, or thioalkoxy; or R 6  and R 7 , independently, can be: wherein R 8  can be selected from hydrogen, halo, cyano, alkyl, haloalkyl, alkenyl, or alkynyl; or R 6  and R 7 , independently, can be: wherein R 9  can be selected from hydrogen, halo, alkyl, haloalkyl, alkenyl, or alkynyl; or R 6  and R 7 , independently, can be: wherein R 10  can be selected from hydrogen, halo, hydroxy, thiol, cyano, alkyl, haloalkyl, alkenyl, alkynyl, amino, or nitro; or R 6  and R 7 , independently, can also be: wherein R 11  can be selected from hydrogen, halo, alkyl, haloalkyl, alkenyl, or alkynyl.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 95.0
- Lexical Diversity: 1.48077
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15613808', '14961325', '13952030', '13503657', '15509722']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7976106066881872
- 35 USC 102 Novelty (BERT): 0.6135695024232376
- Combined Prediction Score: 0.7792064962616922
- Mean Citation Score: 464.73619
- Max Citation Score: 555.94995
- Similarity Product: 482.76502048470667

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test