PATENT CLAIM ANALYSIS

Application Number: 16359464
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["528", "371000"]

Abstract:
Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Claim (Index 41):
A water-soluble conjugated polymer having the structure of the formula: wherein:\n Ar is an aryl or heteroaryl unit substituted with a non-ionic side group capable of imparting solubility in water; \n MU is a polymer modifying unit or band gap modifying unit that is evenly or randomly distributed along the polymer main chain and is optionally substituted with one or more optionally substituted substituents selected from halogen, hydroxyl, C 1 -C 12  alkyl, C 2 -C 12  alkene, C 2 -C 12  alkyne, C 3 -C 12  cycloalkyl, C 1 -C 12  haloalkyl, C 1 -C 12  alkoxy, C 2 -C 18  (hetero)aryloxy, C 2 -C 18  (hetero)arylamino, a C 2 -C 18  (hetero)aryl group and (CH 2 ) x\u2032 (OCH 2 CH 2 ) y\u2032 OCH 3  where x\u2032 is independently an integer from 0-20 and y\u2032 is independently an integer from 0 to 50; \n optional linkers L 1  and L 2  are each independently an aryl or a heteroaryl group evenly or randomly distributed along the polymer main chain and are substituted with one or more pendant chains terminated with: i) a functional group selected from amine, carbamate, carboxylic acid, carboxylate, maleimide, activated ester, N-hydroxysuccinimidyl, hydrazine, hydrazide, hydrazone, azide, alkyne, aldehyde, thiol, and protected groups thereof for conjugation to a molecule or biomolecule; or ii) a conjugated organic dye or biomolecule; \n G 1  and G 2  are each independently selected from hydrogen, halogen, alkyne, optionally substituted aryl, optionally substituted heteroaryl, halogen substituted aryl, boronic acid substituted aryl, boronic ester substituted aryl, boronic ester, boronic acid, optionally substituted fluorene and aryl or heteroaryl substituted with one or more pendant chains terminated with: i) a functional group selected from amine, carbamate, carboxylic acid, carboxylate, maleimide, activated esters, N-hydroxysuccinimidyl, hydrazine, hydrazide, hydrazone, azide, alkyne, aldehyde, thiol, and protected groups thereof for conjugation to a molecule or biomolecule; or ii) a conjugated organic dye or biomolecule; \n wherein: \n n is the number of repeat units; \n the polymer comprises at least 1 functional group selected from amine, carbamate, carboxylic acid, carboxylate, maleimide, activated ester, N-hydroxysuccinimidyl, hydrazines, hydrazide, hydrazone, azide, alkyne, aldehyde, and thiol within G 1 , G 2 , L 1  or L 2 , or a conjugated organic dye or biomolecule; and \n a, b, c and d define the mol % of each unit within the structure which each can be evenly or randomly repeated and where a is a mol % from 10 to 100%, b is a mol % from 0 to 90%, and each c and d are mol % from 0 to 25%.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 99.0
- Lexical Diversity: 1.39216
- Patent Class: 528.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15717502', '16359473', '14821386', '14018985', '13009764']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9041893867904526
- 35 USC 102 Novelty (BERT): 0.7123523083269714
- Combined Prediction Score: 0.8850056789441044
- Mean Citation Score: 760.856188
- Max Citation Score: 764.2056
- Similarity Product: 761.0368090054035

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test