PATENT CLAIM ANALYSIS

Application Number: 16014975
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-11
Patent Classification: ["514", "789000"]

Abstract:
The present invention discloses a new biomarker miR-134, miR-223, or IL-18, which is positively correlated with AOSD and activities thereof. By detecting the expression level of at least one biomarker in a sample, an effect of detecting the risk and prognosis of a sample provider suffering from a disease is achieved.

Claim (Index 3):
A method for detecting the therapeutic effectiveness for adult-onset Still's disease (AOSD), comprising:\n detecting the expression of a biomarker in a sample to obtain a first expression level, wherein the biomarker is selected from the group consisting of miR-134, miR-223 and IL-18; administering a treatment to the sample, wherein the treatment is selected from the group consisting of corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs), and any combination thereof; after the treatment is received, detecting the expression of the biomarker in the sample, to obtain a second expression level; and comparing the first expression level with the second expression level, where when the second expression level is higher than the first expression level, the treatment is shown to be ineffective in the treatment of AOSD; and when the second expression level is lower than the first expression level, the treatment is shown to be effective in the treatment of AOSD.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 94.0
- Lexical Diversity: 1.35714
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14438715', '14989243', '13269404', '13005899', '14380672']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6895669855401289
- 35 USC 102 Novelty (BERT): 0.5137422054258023
- Combined Prediction Score: 0.6719845075286962
- Mean Citation Score: 232.09911
- Max Citation Score: 251.56865
- Similarity Product: 166.5823058005154

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test