PATENT CLAIM ANALYSIS

Application Number: 15868201
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["506", "009000"]

Abstract:
The present invention relates to the identification of chemokine biomarkers predictive of future acute coronary syndromes including unstable angina pectoris (UAP). The present invention also identifies particular chemokines as potential therapeutic targets for intervention in cardiovascular diseases.

Claim (Index 11):
A method for identifying a subject at increased risk of a future acute cardiovascular syndrome or event, the method comprising:\n a) determining an amount of at least one compound selected from the group consisting of CCL3 (chemokine (C-C motif) ligand 3), CCL18 (chemokine (C-C motif) ligand 18), and CCL5 (chemokine (C-C motif) ligand 5) in a sample obtained from the subject by contacting the sample with: i) an antibody specific for CCL3, and quantifying the amount of CCL3 bound to the antibody, ii) an antibody specific for CCL18, and quantifying the amount of CCL18 bound to the antibody, or iii) an antibody specific for CCL5, and quantifying the amount of CCL5 bound to the antibody; b) identifying the subject as having an increased risk of a future acute cardiovascular syndrome or event if the sample from the subject was determined to have greater CCL3, greater CCL5, or greater CCL18 relative to a healthy control; and c) performing follow-up on the subject identified with an increased risk using standard medical therapy.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 1.13889
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12677437', '14388164', '15128560', '15171713', '13575354']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6079380623209077
- 35 USC 102 Novelty (BERT): 0.6623693212132608
- Combined Prediction Score: 0.6133811882101431
- Mean Citation Score: 379.722638
- Max Citation Score: 647.8530000000002
- Similarity Product: 628.9494666656258

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test