PATENT CLAIM ANALYSIS

Application Number: 16069824
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["506", "016000"]

Abstract:
The present invention relates to the field of microfluidics and in particular to analysing the gene expression of a cell in response to a ligand expressed in the same microfluidic compartment. By barcoding the transcriptome of the cell and of the expression system generating the ligand, the effect of the ligand on the cell expression can be discerned. The invention provides microfluidic compartments and methods for this purpose.

Claim (Index 15):
Use of the method of  claim 12  to determine (i) the effect of antibodies on the gene expression of a target cell, wherein the antibodies were raised by immunizing a vertebrate with said target cell or one or more molecules or parts therefrom accessible on its surface, or (ii) the effect of polypeptide ligands on the gene expression of a target cell, wherein the polypeptide ligand is derived from a library.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 95.0
- Lexical Diversity: 1.7561
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15847752', '15980473', '14407849', '13899397', '14586857']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5875780744789745
- 35 USC 102 Novelty (BERT): 0.5144644288918032
- Combined Prediction Score: 0.5802667099202574
- Mean Citation Score: 272.0206380000001
- Max Citation Score: 275.86694
- Similarity Product: 175.56143677120332

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test