PATENT CLAIM ANALYSIS

Application Number: 15918699
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["424", "178100"]

Abstract:
The present invention pertains to a novel and advantageous dosage regimen for a humanized pegylated monovalent anti-CD28 Fab′ antibody fragment, called “FR104”. This dosage regimen consists of between 0.05 and 1.5 mg/kg body weight of FR104, at a dosing schedule of once per week, once every two weeks, once every three weeks, once every four weeks, once every five weeks or once every 6 weeks, once every 7 weeks, once every 8 weeks or once every more than 8 weeks.

Claim (Index 16):
A method of preventing or inhibiting a T cell immune response in a human subject suffering from a condition associated with a T cell immune response comprising administering to the human subject an amount of at least 0.05 up to 1.5 mg/kg body weight of an anti-CD28 Fab\u2032 antibody fragment consisting of a heterodimer of (i) a first protein of SEQ ID NO: 1, which is pegylated at its C-terminus, and (ii) a second protein of SEQ ID NO: 2, at a dosing schedule of once per week, once every two weeks, once every three weeks, once every four weeks, once every five weeks, once every six weeks, once every seven weeks, once every eight weeks, or once every more than eight weeks.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 90.0
- Lexical Diversity: 1.76923
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12710842', '13621590', '11961764', '14042205', '12880623']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7017856328752418
- 35 USC 102 Novelty (BERT): 0.5152393204013704
- Combined Prediction Score: 0.6831310016278547
- Mean Citation Score: 303.536038
- Max Citation Score: 307.80945
- Similarity Product: 220.46815235891643

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test