PATENT CLAIM ANALYSIS

Application Number: 16114430
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-05
Patent Classification: ["514", "340000"]

Abstract:
A compound of formula (I) where R 1 , R 2 , X, Y, n, m, R 3 , R 4 , R 5 , R 6  and R 7  are as defined herein, for use in the prophylaxis or treatment of a central and peripheral nervous system disorder, wherein the compound of formula (I) is administered prior to sleep, before bedtime or at bedtime.

Claim (Index 41):
A method of prophylaxis or treatment of a central and peripheral nervous system disorder, comprising administering to a patient suffering from said disorder, prior to sleep, before bedtime or at bedtime, a therapeutically effective amount of a compound of formula (I) where R 1  and R 2  are the same or different and signify hydrogens, groups hydrolysable under physiological conditions, or optionally substituted alkanoyls or aroyls; X signifies a methylene group; Y represents O, S or NH; n represents 0, 1, 2 or 3; m represents 0 or 1; R 3  signifies a pyridine N-oxide group according to the formula A, B, or C, which is connected as indicated by the unmarked bond: where R 4 , R 5 , R 6  and R 7  are the same or different, and signify hydrogen, alkyl, thioalkyl, alkoxy, aryloxy, thioaryl, alkanoyl, aroyl, aryl, amino, alkylamino, dialkylamino, cycloalkylamino, heterocycloalkylamino, alkylsulphonyl, arylsulphonyl, halogen, haloalkyl, trifluoromethyl, cyano, nitro or heteroaryl; or two or more of R 4 , R 5 , R 6  and R 7  taken together signify aliphatic or heteroaliphatic rings or aromatic or heteroaromatic rings; the term \u2018alkyl\u2019, including its variant \u2018alk-\u2019 in terms such as \u2018alkoxy\u2019, \u2018alkanoyl\u2019 mean carbon residues, straight or branched, containing from one to six carbon atoms; the term \u2018aryl\u2019 means a phenyl or naphthyl group; the term \u2018heterocycloalkyl\u2019 represents a four to eight-membered cyclic ring optionally incorporating at least one atom of oxygen, sulphur or nitrogen; the term \u2018heteroaryl\u2019 represents a five or six-membered ring incorporating at least one atom of sulphur, oxygen or nitrogen; the term \u2018halogen\u2019 represents fluorine, chlorine, bromine or iodine; and if R 4 , R 5 , R 6  and R 7  represent alkyl or aryl they are optionally substituted by one or more hydroxy, alkoxy or halogen groups; or a pharmaceutically acceptable salt ester, carbamate or phosphate thereof.

Metadata:
- Claim Count in Document: 65.0
- Percentile: 96.0
- Lexical Diversity: 1.57143
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13963621', '12524848', '12226260', '15757217', '14532925']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7309371900151075
- 35 USC 102 Novelty (BERT): 0.5658033318642584
- Combined Prediction Score: 0.7144238042000226
- Mean Citation Score: 282.52888
- Max Citation Score: 508.60254
- Similarity Product: 323.8635114106536

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test