PATENT CLAIM ANALYSIS

Application Number: 15522969
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-04
Patent Classification: ["514", "252030"]

Abstract:
Provided herein are compounds and methods for treating a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease. Provided herein are compositions and methods for treating a disorder associated with aberrant Aβ peptide levels, including AD. Provided herein are compounds of Formula (A) or a pharmaceutically acceptable salt thereof, wherein, L′ is selected from the group consisting of C(O), C(R1)(R2), substituted or unsubstituted —C2-6 alkylene-, and substituted or unsubstituted —C3-6 cycloalkylene.

Claim (Index 1):
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein, L 1  is selected from the group consisting of C(O), C(R 1 )(R 2 ), substituted or unsubstituted \u2014C 2-6  alkylene-, and substituted or unsubstituted \u2014C 3-6  cycloalkylene-; Z is selected from the group consisting of halo, CN, OH, C 1-6  alkyl, C 1-6  alkoxy, C 1-3  haloalkyl, C 1-3  haloalkoxy, amino, C 1-3  alkylamino, di(C 1-3  alkyl)amino, substituted or unsubstituted C 3-6  cycloalkyl, substituted or unsubstituted C 4-6  heterocycloalkyl, substituted or unsubstituted heteroaryl, and a group of Formula (Z-1): or L 1  is absent and Z is selected from the group consisting of substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, and substituted or unsubstituted heteroaryl; R 1  and R 2  are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, COOR 1A , \u2014CONR 1A R 1B , or are optionally joined together to form a substituted or unsubstituted cycloalkyl; R 3  is hydrogen, halogen, \u2014CF 3 , \u2014CN, \u2014OR 3A , \u2014NR 3A R 3B , \u2014COOR 3A , \u2014CONR 3A R 3B , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; R 4  is hydrogen, halogen, \u2014CF 3 , \u2014CN, \u2014OR 4A , NR 4A R 4B , \u2014COOR 4A , \u2014CONR 4A R 4B , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; or R 3  and R 4  are optionally joined together to form a substituted or unsubstituted cycloalkyl; R 5  is independently hydrogen, halogen, \u2014CF 3 , \u2014CN, \u2014OR 5A , \u2014NR 5A R 5B , \u2014COOR 5A , \u2014CONR 5A R 5B , \u2014SR 5A , \u2014OCF 3 , \u2014OCHF 2 , substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl; R 6  and R 7  are independently substituted or unsubstituted C 1 -C 5  alkyl; R 1A , R 1B , R 3A , R 3B , R 4A , R 4B , R 5A , and R 5B  are independently hydrogen, \u2014OH, \u2014NH 2 , substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or R 1A  and R 1B , R 3A  and R 3B , R 4A  and R 4B , or R 5A  and R 5B  are independently optionally joined together to independently form a substituted or unsubstituted heterocycloalkyl, or substituted or unsubstituted heteroaryl; R 8  is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted heteroalkyl; and z1 is an integer of 0, 1, 2, 3, 4, or 5.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 91.0
- Lexical Diversity: 1.77358
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15421258', '14775483', '14992396', '14550528', '13806692']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8087170052151322
- 35 USC 102 Novelty (BERT): 0.5415873839827154
- Combined Prediction Score: 0.7820040430918906
- Mean Citation Score: 364.897392
- Max Citation Score: 378.66806
- Similarity Product: 276.1508428002668

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test