PATENT CLAIM ANALYSIS

Application Number: 15918626
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "04400A"]

Abstract:
The subject invention pertains to biomarkers for identifying BC in a subject. The biomarkers presented herein include miRNAs, particularly, a combination of miRNAs. The invention demonstrates that the specific miRNAs are increased body fluid, particularly, urine, from a subject compared to that of a control. Accordingly, the levels of specific mRNAs, in a body fluid, particularly, urine, from a subject is used to diagnose BC in a subject. The invention also provides kits and reagents to conduct assays to quantify biomarkers described herein. The invention further provides methods of treating and/or managing BC in a subject.

Claim (Index 16):
The assay of  claim 12 , comprising determining in the test sample and, if obtained, the control sample, the levels of two or more miRNAs from Panel 25,\n wherein the assay comprises: a) contacting the test sample, and if obtained, the control sample, with a combination of primer pairs and probes and conducting a PCR, wherein each combination of a primer pair and a probe from said combinations of primer pairs and probes amplifies and detects one miRNA in the miRNAs from Panel 25, and c) detecting the presence and quantity of the two or more miRNAs based on the qPCR in the test sample, and if obtained, the control sample.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 2.15385
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15300808', '13746589', '14755261', '15852128', '15318646']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6143314871611585
- 35 USC 102 Novelty (BERT): 0.4966825808638427
- Combined Prediction Score: 0.602566596531427
- Mean Citation Score: 209.242642
- Max Citation Score: 225.11575
- Similarity Product: 160.07912151665985

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test