PATENT CLAIM ANALYSIS

Application Number: 15957550
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
Described herein are iDNA vectors and vaccines and methods for using the same. The iDNA generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses, particularly yellow fever virus and Venezuelan equine encephalitis virus. When iDNA is injected into the vaccine recipient, RNA of live attenuated virus is generated by in vivo transcription in the recipient's tissues. This initiates production of progeny attenuated viruses in the tissues of the vaccine recipient, as well as elicitation of an effective immune response protecting against wild-type, non-attenuated virus.

Claim (Index 46):
A vaccine for an infectious RNA virus comprising a therapeutically effective amount of a homogeneous clonally pure live attenuated virus prepared from cultured cells transfected with a vector comprising DNA encoding:\n (a) an infectious RNA molecule that encodes a non-pathogenic alphavirus; and (b) a eucaryotic RNA polymerase promoter; wherein the DNA encoding an infectious RNA molecule is operably linked to the RNA polymerase promoter.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 91.0
- Lexical Diversity: 1.63934
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14168788', '13054372', '13519948', '14790960', '14787098']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7801554319869954
- 35 USC 102 Novelty (BERT): 0.6375586507694894
- Combined Prediction Score: 0.7658957538652449
- Mean Citation Score: 476.1827520000001
- Max Citation Score: 623.634
- Similarity Product: 569.4058987380265

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test