PATENT CLAIM ANALYSIS

Application Number: 16047915
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "303000"]

Abstract:
Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and related compounds, which are useful as inhibitors of ENPP1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the ENPP1.

Claim (Index 1):
A compound of Formula I: wherein Y is S; Z is \u2014H or \u2014N; X 1  is \u2014C\u2550O or \u2014NH, X 2  is \u2014C\u2550O or \u2014NH, provided that if X 1  is \u2014C\u2550O, then X 2  is \u2014NH; and if X 1  is \u2014NH, then X 2  is \u2014C\u2550O; R 1  is selected from the group consisting of \u2014H, halogen, \u2014OCF 3 , \u2014CF 3 , \u2014CN, OCH 3 , and \u2014CH 3 ; R 2  is selected from the group consisting of \u2014H, \u2014NH 2 , \u2014OH, and \u2014CH 3 ; R 3  is selected from the group consisting of \u2014H, \u2014NH 2 , \u2014OH, and \u2014CH 3 ; R 4  is selected from the group consisting of \u2014H, \u2014CH 2 \u2014CH 3  and \u2014CH 3 ; R 5  is selected from the group consisting of and R 6  is selected from the group consisting of \u2014OCH 3 , OH, F, Cl, \u2014CH 3 , O\u2014CH 2 \u2014CH 3 , and OCH 2 \u2014CF 3 , OCHF 2 , or an isomer or a pharmaceutically acceptable salt thereof.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 95.0
- Lexical Diversity: 1.5122
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15314938', '13905410', '12334371', '13470122', '15875678']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7813387181331766
- 35 USC 102 Novelty (BERT): 0.5077125613703566
- Combined Prediction Score: 0.7539761024568946
- Mean Citation Score: 243.805358
- Max Citation Score: 246.33662
- Similarity Product: 154.04148064157133

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test