PATENT CLAIM ANALYSIS

Application Number: 15535222
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["436", "064000"]

Abstract:
The present disclosure is drawn to methods of diagnosing and classifying pancreatic cancer by examining the expression of particular metabolites that distinguish this disease state from benign disease and periampullary adenocarcinoma.

Claim (Index 2):
The method of  claim 1 , wherein step (b) comprises determining the levels of Galactose, Unmatched RI:1007.82 QI: 67/82/83, Isopropanol, Mannose, Trimethylamine-N-oxide, Arabitol, Threitol, Succinate, Trehalose-alpha, Match RI:2018.25 QI: 191/217/305/318/507, Tridecanol, Azelaic acid, Unmatched RI:2475.33 QI: 73/375/376, Pyroglutamate, Isoleucine, Tyrosine, Arginine, Unmatched RI:1913.88 QI: 156/174/317, Alanine, Creatine, Lysine, Unmatched RI:1971.99 QI: 185/247/275; and step (c) comprises assigning to said sample a classification as pancreatic cancer or periampullary adenocarcinoma where a pluraliity of Galactose, Unmatched RI:1007.82 QI: 67/82/83, Isopropanol, Mannose, Trimethylamine-N-oxide, Arabitol, Threitol, Succinate, and Trehalose-alpha levels are elevated; and benign pancreatic lesion where a plurality of Match RI:2018.25 QI: 191/217/305/318/507, Tridecanol, Azelaic acid, Unmatched RI:2475.33 QI: 73/375/376, Pyroglutamate, Isoleucine, Tyrosine, Arginine, Unmatched RI:1913.88 QI: 156/174/317, Alanine, Creatine, Lysine, Unmatched RI:1971.99 QI: 185/247/275 levels are elevated.

Metadata:
- Claim Count in Document: 10.0
- Percentile: 86.0
- Lexical Diversity: 1.10345
- Patent Class: 436.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14671062', '14753249', '14632480', '13371969', '15116272']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.656368854972044
- 35 USC 102 Novelty (BERT): 0.4762148037661976
- Combined Prediction Score: 0.6383534498514594
- Mean Citation Score: 182.267954
- Max Citation Score: 185.58125
- Similarity Product: 128.40943267978727

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test