PATENT CLAIM ANALYSIS

Application Number: 15893102
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "139100"]

Abstract:
Provided are methods for clinical treatment of hematological malignancies, such as relapsed or refractory chronic lymphocytic leukemia or lymphoma using an anti-LAG-3 antibody. Particular malignancies include, e.g., chronic lymphocytic leulcemia (CLL), Hodgkin lymphoma (HL), or non-Hodgkin lymphoma (NHL).

Claim (Index 15):
A method of treating a hematological malignancy in a human patient, the method comprising administering to the patient an effective amount of a full-length human anti LAG-3 antibody comprising:\n (a) a heavy chain variable region CDR1 having the sequence set forth in SEQ ID NO:7; (b) a heavy chain variable region CDR2 having the sequence set forth in SEQ ID NO:8; (c) a heavy chain variable region CDR3 having the sequence set forth in SEQ ID NO:9; (d) a light chain variable region CDR1 having the sequence set forth in SEQ ID NO: 10; (e) a light chain variable region CDR2 having the sequence set forth in SEQ ID NO: 11; and (f) a light chain variable region CDR3 having the sequence set forth in SEQ ID NO: 12, wherein the method comprises at least one administration cycle, wherein the cycle is a period of eight weeks, wherein for each of the at least one cycles, the anti-LAG-3 antibody is administered as follows: (i) four doses of 20 mg anti-LAG-3 antibody; (ii) four doses of 80 mg anti-LAG-3 antibody; (iii) four doses of 240 mg anti-LAG-3 antibody; or (iv) four doses of 800 mg anti-LAG-3 antibody.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 88.0
- Lexical Diversity: 1.45714
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15021102', '15032919', '14437029', '15703126', '15166114']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7677287990713204
- 35 USC 102 Novelty (BERT): 0.5680377653213423
- Combined Prediction Score: 0.7477596956963226
- Mean Citation Score: 420.279788
- Max Citation Score: 491.10278
- Similarity Product: 367.0885863944029

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test