PATENT CLAIM ANALYSIS

Application Number: 15743248
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["800", "008000"]

Abstract:
The present invention provides genetically modified non-human animals which are deficient in at least one or more types of CD3 genes selected from the group consisting of endogenous CD3ε, CD3δ, and CD3γ in its genome and functionally express at least one or more types of human CD3 genes selected from the group consisting of human CD3ϵ, CD3δ, and CD3γ. In the genetically modified non-human animals of the present invention, mature T cell differentiation and production can take place, and immunocompetent cells including T cells can exert their functions. The genetically modified non-human animals of the present invention enable efficient evaluation and screening in the development of therapeutic agents and therapeutic methods that use human CD3-mediated targeted drugs.

Claim (Index 20):
A genetically modified non-human animal produced according to the method of  claim 11 .

Metadata:
- Claim Count in Document: 24.0
- Percentile: 86.0
- Lexical Diversity: 1.8806
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13661342', '15830605', '14342060', '15601363', '14152090']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5837318818284084
- 35 USC 102 Novelty (BERT): 0.5251269639255512
- Combined Prediction Score: 0.5778713900381227
- Mean Citation Score: 319.2994520000001
- Max Citation Score: 365.5469
- Similarity Product: 226.0858531923712

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test