PATENT CLAIM ANALYSIS

Application Number: 15952680
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["536", "024500"]

Abstract:
This invention provides UNA oligomers for therapeutics having prolonged stability. The UNA oligomers can be composed of one or more 2′-3′-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers. Embodiments include UNA oligomers with phosphorothioate or boranophosphate intermonomer linkages. The UNA oligomers can be used for therapeutics that target oligonucleotides, nucleic acids, or RNAs to reduce their activity.

Claim (Index 25):
An oligomer comprising one or more 2\u2032-3\u2032-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers, wherein the oligomer is a duplex having sense and antisense strands, wherein one or more of the 2\u2032-3\u2032-seco-nucleomonomers are in the antisense strand in positions 1-8 counted from the 5\u2032 end, and wherein the 2\u2032-3\u2032-seco-nucleomonomers are monomer D wherein Base is a nucleobase.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.47727
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14702991', '14703016', '13652965', '15050065', '12515403']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7237532191860716
- 35 USC 102 Novelty (BERT): 0.6212876195861265
- Combined Prediction Score: 0.713506659226077
- Mean Citation Score: 592.37655
- Max Citation Score: 598.10767
- Similarity Product: 525.2602558924376

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test