PATENT CLAIM ANALYSIS

Application Number: 15987458
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["544", "237000"]

Abstract:
The present invention relates to a class of substituted triazolopiperazine compounds, tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.

Claim (Index 1):
Substituted triazolopiperazine compound represented by formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, pharmaceutically acceptable salts, esters, prodrugs or hydrates thereof: wherein, Y is A and B are each independently hydrogen or substituted or unsubstituted C1-C8 alkyl, wherein the substituent in the substituted C1-C8 alkyl is selected from one or more of the group consisting of halogen, cyano, nitro, hydroxyl and amino; alternatively, A and B together with the carbon atoms to which they are attached form a substituted or unsubstituted C4-C8 aliphatic ring, a substituted or unsubstituted C6-C10 aromatic ring, a substituted or unsubstituted 4-8 membered heterocyclic ring containing 1-3 heteratoms selected from N, O and S, or a substituted or unsubstituted 5-8 membered heteroaromatic ring containing 1-3 heteratoms selected from N, O, and S; wherein the substituent in the substituted rings is selected from one or more of the group consisting of halogen, cyano, nitro, hydroxyl, and amino; X is hydrogen, halogen, hydroxyl, or cyano; R is halogen, COOR 1 , substituted or unsubstituted heterocyclic ring, substituted or unsubstituted heteroaromatic ring, substituted or unsubstituted aromatic ring, wherein the substituent in the substituted heterocyclic ring, heteroaromatic ring or aromatic ring is selected from one or more of the group consisting of substituted or unsubstituted C1-C8 alkyl, halogen, cyano, nitro, hydroxyl, amino, C1-C6 alkoxy, C2-C6 alkylcarbonyl, C2-C6 alkoxycarbonyl, C2-C6 alkenyl, C2-C6 alkynyl, and C6-C10 aryl, wherein the substituent in the substituted C1-C8 alkyl is selected from one or more of the group consisting of halogen, cyano, nitro, hydroxyl, amino; R 1  is selected from the group consisting of hydrogen, C1-C8 alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heterocyclyl, wherein the substituent in the substituted aryl or heterocyclyl is selected from one or more of the group consisting of C1-C8 alkyl, halogen, cyano, nitro, hydroxyl, amino, C1-C6 alkoxy, C2-C6 alkylcarbonyl, C2-C6 alkoxycarbonyl, C2-C6 alkenyl, C2-C6 alkynyl, and C6-C10 aryl.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 93.0
- Lexical Diversity: 1.44898
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14418705', '15708917', '13035640', '16060701', '11849230']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.829504073172935
- 35 USC 102 Novelty (BERT): 0.5532616459936309
- Combined Prediction Score: 0.8018798304550045
- Mean Citation Score: 337.94636
- Max Citation Score: 431.5869
- Similarity Product: 378.553380875963

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test