PATENT CLAIM ANALYSIS

Application Number: 15863216
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "221000"]

Abstract:
The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: These compounds are useful for treating Respiratory Syncytial Virus (RSV) infection. The present invention further relates to pharmaceutical compositions comprising these compounds for administration to a subject suffering from RSV infection. The invention also relates to methods of treating an RSV infection in a subject by administering to the subject a pharmaceutical composition comprising a compound of the invention.

Claim (Index 1):
A compound represented by Formula (I), or a pharmaceutically acceptable salt thereof: wherein: A is heteroaryl; B is selected from the group consisting of: R 1  is optionally substituted aryl or optionally substituted heteroaryl; R 2  is selected from the group consisting of: 1) Optionally substituted \u2014C 3 -C 12  cycloalkyl; 2) Optionally substituted \u2014C 3 -C 12  cycloalkenyl; 3) Optionally substituted 3- to 12-membered heterocyclyl; 4) Optionally substituted aryl; 5) Optionally substituted heteroaryl; 6) \u2014NR 13 R 14 ; 7) \u2014CO\u2014NR 13 R 14 ; and 8) \u2014SO 2 \u2014NR 13 R 14 ; Each R 3  is the same or different and independently selected from halogen, hydroxyl, protected hydroxyl, cyano, amino, protected amino, nitro, optionally substituted \u2014C 1 -C 8  alkyl, optionally substituted \u2014C 1 -C 8  alkoxy, optionally substituted \u2014NHC 1 -C 8  alkyl, optionally substituted \u2014S\u2014(\u2014C 1 -C 8  alkyl), optionally substituted \u2014SO 2 \u2014(\u2014C 1 -C 8  alkyl), \u2014optionally substituted \u2014SO 2 \u2014NH\u2014(\u2014C 1 -C 8  alkyl), optionally substituted \u2014NH\u2014SO 2 \u2014(\u2014C 1 -C 8  alkyl), \u2014CO 2 R 11 , \u2014NR 13 R 14 , and \u2014CO\u2014NR 13 R 14 ; Each R 11  is independently selected from the group consisting of: 1) Optionally substituted \u2014C 1 -C 8  alkyl; 2) Optionally substituted \u2014C 2 -C 8  alkenyl; 3) Optionally substituted \u2014C 2 -C 8  alkynyl; 4) Optionally substituted \u2014C 3 -C 8  cycloalkyl; 5) Optionally substituted \u2014C 3 -C 8  cycloalkenyl; 6) Optionally substituted 3- to 8-membered heterocycloalkyl; 7) Optionally substituted aryl; and 8) Optionally substituted heteroaryl; and R 13  and R 14  are each independently selected from hydrogen, optionally substituted \u2014C 1 -C 8 -alkyl, optionally substituted \u2014C 2 -C 8 -alkenyl, optionally substituted \u2014C 2 -C 8 -alkynyl; optionally substituted \u2014C 3 -C 8 -cycloalkyl, optionally substituted \u2014C 1 -C 8 -alkoxy, \u2014S(O) 2 R 11 , and \u2014S(O) 2 NHR 11 ; alternatively, R 13  and R 14  are taken together with the nitrogen atom to which they attached to form a heterocyclic ring; and depending on the heteroaryl group, and n is 0 to k, where k is the total number of CH and NH groups in group A when A is unsubstituted.

Metadata:
- Claim Count in Document: 21.0
- Percentile: 86.0
- Lexical Diversity: 1.65385
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15216119', '11503502', '15772893', '14142666', '15209150']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7826213919271728
- 35 USC 102 Novelty (BERT): 0.5333053996280719
- Combined Prediction Score: 0.7576897926972628
- Mean Citation Score: 287.27602000000013
- Max Citation Score: 350.20874
- Similarity Product: 281.55301338572986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test