PATENT CLAIM ANALYSIS

Application Number: 16198902
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["435", "006120"]

Abstract:
The present invention provides methods, compositions and kits for enriching and determining nucleotide sequences of a plurality of target loci from a sample comprising nucleic acids. The methods comprise one or more cycles of primer extension followed by PCR amplification of target sequences using nested target-specific primers.

Claim (Index 3):
The method according to  claim 1 , characterized in that:\n (1) the nucleic acid template is genomic DNA, optionally, the genomic DNA is chromosomal DNA, or the genomic DNA is mitochondrial DNA or other extra-chromosomal DNA; (2) the nucleic acid template is exome DNA; or (3) the nucleic acid template is cDNA, optionally, the cDNA is obtained by reverse transcription of total RNA, or the cDNA is obtained by reverse transcription of mRNA, miRNA, or other noncoding RNAs; or (4) the nucleic acid sample comprises both genomic DNA and cDNA; or (5) the nucleic acid template is cell-free DNA; and/or (6) the nucleic acid sample is derived from a blood sample; and/or (7) the nucleic acid sample is derived from a cell or tissue sample, optionally, the nucleic acid sample is derived from a tumor biopsy sample, and/or the nucleic acid sample is derived from a Formalin-Fixed Paraffin-Embedded (FFPE) sample.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 98.0
- Lexical Diversity: 1.25
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14463498', '13793564', '15269448', '12069174', '14300048']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5918139572428815
- 35 USC 102 Novelty (BERT): 0.5352323966050951
- Combined Prediction Score: 0.5861558011791029
- Mean Citation Score: 339.0472660000001
- Max Citation Score: 356.35602
- Similarity Product: 242.22853186095

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test