PATENT CLAIM ANALYSIS

Application Number: 15750982
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2018-11
Patent Classification: ["424", "001490"]

Abstract:
The present invention relates to antibody-based molecules (including single domain antibody fragment, scFv molecules, antibodies, antibody fragments, diabodies, and the epitope-binding domains thereof) that are capable of immunospecifically and selectively binding to the  {p} Ser404 Epitope of Tau. Such antibody-based molecules are useful to detect pathological Tau protein conformer if present in a biological sample, especially in conjunction with the diagnosis and/or treatment of Alzheimer's disease or other tauopathy, and thus provide a diagnostic for Alzheimer's disease and other Tau pathologies. The antibody -based molecules of the present invention have particular utility as diagnostic markers for, Alzheimer's disease and related tauopathies and as pharmaceutical compositions for the treatment of such conditions.

Claim (Index 3):
The antibody-based molecule of  claim 1 , wherein said molecule is an antibody or comprises an epitope-binding fragment of an antibody.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 95.0
- Lexical Diversity: 1.65385
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15324141', '15207836', '14654176', '15397569', '12813297']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7585241374042945
- 35 USC 102 Novelty (BERT): 0.6286224769267644
- Combined Prediction Score: 0.7455339713565415
- Mean Citation Score: 490.806366
- Max Citation Score: 594.638
- Similarity Product: 521.1970233511925

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test