PATENT CLAIM ANALYSIS

Application Number: 15742063
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "340000"]

Abstract:
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Claim (Index 1):
Compound of the formula in which R 1  represents a group of the formula where * is the point of attachment to the oxopyridine ring, R 6  represents chlorine or methyl, R 7  represents 5- or 6-membered heterocyclyl,\n where heterocyclyl may be substituted by a substituent selected from the group consisting of oxo, chlorine, fluorine, hydroxy, methyl, difluoromethyl, trifluoromethyl and 2,2,2-trifluoroethyl, \n R 8  represents hydrogen or fluorine, R 2  represents chlorine, methyl or methoxy, R 3  represents hydrogen, C 1 -C 5 -alkyl, 1,1-difluoroethyl, 3,3,3-trifluoro-2-methoxyprop-1-yl or 3,3,3-trifluoro-2-ethoxyprop-1-yl,\n where alkyl may be substituted by a substituent selected from the group consisting of fluorine, hydroxy, difluoromethyl, trifluoromethyl, methoxy, ethoxy, tert-butoxy, isopropoxy, difluoromethoxy, trifluoromethoxy, C 3 -C 6 -cycloalkyl, 4- to 6-membered oxoheterocyclyl, 1,4-dioxanyl, pyrazolyl, phenyl, pyridyl, C 3 -C 6 -cycloalkyloxy and 4- to 6-membered oxoheterocyclyloxy,\n in which tert-butoxy and isopropoxy may be substituted by 1 to 3 fluorine substituents, \n and \n where cycloalkyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of fluorine, hydroxy, methyl, ethyl, methoxy, ethoxy, difluoromethyl, trifluoromethyl, difluoromethoxy and trifluoromethoxy, \n and \n in which oxoheterocyclyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of fluorine, methyl, ethyl, difluoromethyl and trifluoromethyl, \n and \n in which pyrazolyl is substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine, methyl and ethyl, \n and \n in which cycloalkyloxy and oxoheterocyclyloxy may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of fluorine and methyl, \n \n R 4  represents hydrogen, R 5  represents a group of the formula where # is the point of attachment to the nitrogen atom, R 9  represents hydroxycarbonyl or 5-membered heterocyclyl, R 10  represents hydrogen or fluorine, R 11  and R 12  together with the carbon atoms to which they are attached form a 5-membered heterocycle,\n where the heterocycle may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, hydroxy, hydroxycarbonyl, methyl, ethyl, 2-hydroxyethyl, difluoromethyl, trifluoromethyl, cyclopropylmethyl, trideuteromethyl, 2,2-difluoroethyl and 2,2,2-trifluoroethyl, \n R 13  represents hydrogen or fluorine, R 14  represents hydrogen or fluorine, R 15  represents hydrogen or fluorine, R 16  represents hydrogen, C 1 -C 4 -alkyl or cyclopropyl, R 17  represents hydrogen or fluorine, R 18  represents hydroxy or \u2014NHR 19 ,\n in which \n R 19  represents hydrogen, C 1 -C 4 -alkyl or cyclopropyl, \n R 20  represents hydrogen or fluorine, R 21  represents hydroxy or \u2014NHR 22 ,\n in which \n R 22  represents hydrogen, C 1 -C 4 -alkyl or cyclopropyl, \n R 26  represents hydrogen, methyl or trifluoromethyl, R 27  represents hydrogen, methyl or trifluoromethyl, R 28  represents hydrogen, cyano, methyl, trifluoromethyl or amino, or one of the salts thereof, solvates thereof or solvates of the salts thereof.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.44118
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15032212', '15513930', '14780925', '15514276', '15513853']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8319065599694966
- 35 USC 102 Novelty (BERT): 0.5842052602561094
- Combined Prediction Score: 0.8071364299981579
- Mean Citation Score: 454.557378
- Max Citation Score: 500.20227
- Similarity Product: 409.3294750588704

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test