PATENT CLAIM ANALYSIS

Application Number: 15747980
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-12
Patent Classification: ["546", "045000"]

Abstract:
There is provided a novel process for the preparation of a compound of formula (I), wherein R 1  is as described in the description, by demethylation of a corresponding O-methyl derivative.

Claim (Index 16):
A process as claimed in  claim 1 , wherein the compound of formula I is hydromorphone, and the process comprises contacting hydrocodone or a salt thereof, with a mixture comprising water and:\n (i) a carboxylic acid selected from the group consisting of trifluoroacetic acid, trichloroacetic acid, difluoroacetic acid, dichloroacetic acid, fluoroacetic acid, chloroacetic acid, and mixtures thereof; (ii) a sulfonic acid selected from the group consisting of methane sulfonic acid, trifluoromethane sulfonic acid, toluenesulfonic acid, and mixtures thereof; and (ii) a sulfide compound selected from the group consisting of dioctyl sulfide, dibutyl sulfide, dipropyl sulfide, diethyl sulfide, dimethyl sulfide, dodecyl methyl sulfide and mixtures thereof.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 86.0
- Lexical Diversity: 1.24138
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14906776', '15644266', '13686725', '15039681', '14692526']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.752928876844371
- 35 USC 102 Novelty (BERT): 0.4821126484566165
- Combined Prediction Score: 0.7258472540055956
- Mean Citation Score: 192.399404
- Max Citation Score: 205.97032
- Similarity Product: 151.886662559762

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test