PATENT CLAIM ANALYSIS

Application Number: 15995286
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "134100"]

Abstract:
The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.

Claim (Index 21):
The recombinant ROBO2 protein of  claim 1 , wherein said protein has a half maximal inhibitory concentration (IC 50 ) of not more than about 15 nM, about 13 nM, about 11 nM, about 9 nM, about 7 nM, about 6 nM, about 5 nM, about 4 nM, about 3 nM, about 2 nM, about 1 nM, as measured by a homogenous time-resolved fluorescence (HTRF) assay for inhibition of binding of ROBO2 to SLIT2.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 94.0
- Lexical Diversity: 1.1875
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15399848', '14369094', '13641012', '10574084', '14170166']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7936383294114753
- 35 USC 102 Novelty (BERT): 0.5464834444921791
- Combined Prediction Score: 0.7689228409195458
- Mean Citation Score: 365.702406
- Max Citation Score: 417.4305
- Similarity Product: 264.27712930414083

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test