PATENT CLAIM ANALYSIS

Application Number: 15912075
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-12
Patent Classification: ["435", "208000"]

Abstract:
In one embodiment, the invention provides a method of purifying recombinant alpha-galactosidase A. The method includes obtaining a lysate from cells recombinantly expressing alpha-galactosidase A grown in a cell culture medium having non-precipitating phosphate; contacting said lysate with a first chromatography media that binds α-D-mannopyranosyl or α-D-glucopyranosyl; eluting alpha-galactosidase A from the first chromatography media to generate a first eluate having alpha-galactosidase A, wherein said eluting includes at least one elution pause between 4 and 16 hours; contacting the first eluate with a second chromatography media that binds galactose binding proteins; and eluting alpha-galactosidase A from said second chromatography media to generate a second eluate containing said recombinant alpha-galactosidase A.

Claim (Index 24):
The method according to  claim 21 , wherein said elution pause is between 10 and 14 hours.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 90.0
- Lexical Diversity: 1.90323
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14732662', '15545194', '13188907', '14416539', '14573907']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5970166651016798
- 35 USC 102 Novelty (BERT): 0.6756025748439854
- Combined Prediction Score: 0.6048752560759104
- Mean Citation Score: 332.94936
- Max Citation Score: 791.4735
- Similarity Product: 640.1645098282098

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test