PATENT CLAIM ANALYSIS

Application Number: 15752900
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["424", "449000"]

Abstract:
The present application is directed to transdermal formulations for the delivery of berberine compounds to a subject for the treatment of berberine-responsive diseases. In particular, the transdermal formulation comprises: (a) an aqueous phase comprising water and at least one water soluble emulsion stabilizer; (b) an oil phase comprising at least one emulsifier, at least one oil soluble emulsion stabilizer, at least one emollient comprising at least one flavonoid and at least one other emollient; wherein the oil and aqueous phases form an emulsion; (c) an external phase comprising at least one flavonoid containing-extract, at least one phospholipid-complexed flavonoid and at least one source of berberine or analog or derivative thereof; and optionally (d) at least one preservative phase.

Claim (Index 20):
The method of  claim 19 , wherein the berberine-responsive disease or condition is selected from one or more of Type I diabetes, Type 2 diabetes, pre-type I diabetes, pre-type 2 diabetes, hyperlipidemia, pre-hyperlipidemia, heart disease, inflammatory disease, skin disease, metabolic disease, neurological disease, and cancer, wherein the cancer is selected from hepatoma, colon cancer, lung cancer, breast cancer and leukemia.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 88.0
- Lexical Diversity: 2.20968
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15681950', '14576476', '15022951', '12258341', '14857772']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7078996486682116
- 35 USC 102 Novelty (BERT): 0.5010559060142412
- Combined Prediction Score: 0.6872152744028147
- Mean Citation Score: 204.80555400000003
- Max Citation Score: 206.40686
- Similarity Product: 130.79635135899662

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test