PATENT CLAIM ANALYSIS

Application Number: 16178817
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-09
Patent Classification: ["514", "248000"]

Abstract:
3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating medical disorders related to SSTR4.

Claim (Index 1):
A compound of the formula (I) wherein\n A is selected from the group consisting of\n H and C 1-6 -alkyl; \n \n R 1  and R 2  are independently selected from the group consisting of\n H, C 1-6 -alkyl and C 3-6 -cycloalkyl, wherein at least one of R 1  or R 2  is C 1-6 -alkyl or C 3-6 -cycloalkyl, \n wherein the C 1-6 -alkyl or the C 3-6 -cycloalkyl is optionally substituted with halogens or MeO\u2014, or \n wherein R 1  and R 2  together form a 2- to 5-membered alkylene-bridge optionally substituted with halogens incorporating 0 to 2 heteroatoms independently selected from the group consisting of N, O and S; \n \n W is selected from the group consisting of a\n mono- or bicyclic aryl, a mono- or bicyclic heteroaryl, a mono- or bicyclic heterocyclyl and a mono- or bicyclic cycloalkyl,\n wherein each of these ring systems are optionally substituted with one or more R 3 , and \n wherein the heteroaryl comprises up to 4 heteroatoms and one or two 5- or 6-membered ring(s); \n \n \n R 3  is independently selected from the group consisting of\n C 1-6 -alkyl, C 3-8 -cycloalkyl, C 1-6 -alkyl-O\u2014, benzyl, halogen, HO\u2014, NC\u2014, mono- or bicyclic heteroaryl, and 5- or 6-membered monocyclic heterocyclyl containing one heteroatom selected from the group consisting of N, O or S(O) r , wherein the heteroaryl contains up to 4 heteroatoms and one or two 5- or 6-membered rings(s) and r is 0, 1 or 2,\n wherein the C 1-6 -alkyl, C 3-8 -cycloalkyl, C 1-6 -alkyl-O\u2014, benzyl, heteroaryl and the heterocyclyl are optionally substituted with halogens, HO\u2014, acetyl, C 1-6 -alkyl-O\u2014, oxo, R 4 \u2014S(O) 2 \u2014, with R 4  being aryl, C 3-6 -cycloalkyl and/or C 1-6 -alkyl; and \n \n \n Y is selected from the group consisting of a bond, \u2014CH 2 \u2014, \u2014CH 2 CH 2 \u2014, and \u2014CH 2 O\u2014; \n or a salt thereof.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 98.0
- Lexical Diversity: 1.03333
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14275879', '15685588', '15526361', '16048665', '15526360']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8541863493218947
- 35 USC 102 Novelty (BERT): 0.5681558054888407
- Combined Prediction Score: 0.8255832949385893
- Mean Citation Score: 427.91361400000005
- Max Citation Score: 444.39554
- Similarity Product: 429.98874894390815

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test