PATENT CLAIM ANALYSIS

Application Number: 15742542
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "133100"]

Abstract:
The present invention provides a method using IL-17 antagonistic antibodies for treating pruritus.

Claim (Index 1):
A method of treating pruritus comprising administering to a patient with pruritus a therapeutically effective amount of an IL-17 antagonistic antibody, wherein said antibody comprises a light chain and a heavy chain, wherein the light chain comprises a light chain variable region (LCVR) and the heavy chain comprises a heavy chain variable region (HCVR), wherein the LCVR comprises LCDR1, LCDR2, and LCDR3, and the HCVR comprises HCDR1, HCDR2, and HCDR3, wherein:\n a. LCDR1 comprises the amino acid sequence of SEQ ID NO: 1, LCDR2 comprises the amino acid sequence of SEQ ID NO: 2, and LCDR3 comprises the amino acid sequence of SEQ ID NO: 3, and HCDR1 comprises the amino acid sequence of SEQ ID NO: 4, HCDR2 comprises the amino acid sequence of SEQ ID NO: 5, and HCDR3 comprises the amino acid sequence of SEQ ID NO: 6; or b. LCDR1 comprises the amino acid sequence of SEQ ID NO: 11, LCDR2 comprises the amino acid sequence of SEQ ID NO: 12, and LCDR3 comprises the amino acid sequence of SEQ ID NO: 13, and HCDR1 comprises the amino acid sequence of SEQ ID NO: 14, HCDR2 comprises the amino acid sequence of SEQ ID NO: 15, and HCDR3 comprises the amino acid sequence of SEQ ID NO: 16; or c. LCDR1 comprises the amino acid sequence of SEQ ID NO: 21, LCDR2 comprises the amino acid sequence of SEQ ID NO: 22, and LCDR3 comprises the amino acid sequence of SEQ ID NO: 23, and HCDR1 comprises the amino acid sequence of SEQ ID NO: 24, HCDR2 comprises the amino acid sequence of SEQ ID NO: 25, and HCDR3 comprises the amino acid sequence of SEQ ID NO: 26.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 86.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15679190', '13055201', '15711815', '14661334', '15223434']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.742906935528644
- 35 USC 102 Novelty (BERT): 0.5392844842106601
- Combined Prediction Score: 0.7225446903968457
- Mean Citation Score: 373.05232
- Max Citation Score: 395.62125
- Similarity Product: 282.5257280892134

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test