PATENT CLAIM ANALYSIS

Application Number: 16252053
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["424", "094300"]

Abstract:
Disclosed are new small molecules having a 4-methylpyrrrolo[1,2-a]pyrimidine-8-carboxamide core structure and the uses thereof for modulating glucocerebrosidase activity. Also disclosed are pharmaceutical compositions comprising the small molecules which may be administered in methods of treating diseases or disorders associated with glucocerebrosidase activity, including neurological diseases and disorders such as Gaucher's disease and Parkinson's disease. The small molecules may contain a fluorophore or may be conjugated to a fluorophore in order to prepare a fluorescent probe for use in high throughput screening methods to identify new modulators of glucocerebrosidase activity via fluorescence polarization.

Claim (Index 23):
The compound of  claim 21  having a formula selected from:

Metadata:
- Claim Count in Document: 29.0
- Percentile: 99.0
- Lexical Diversity: 1.5
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['16021972', '15789645', '15199220', '16175220', '15199207']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8052507570897689
- 35 USC 102 Novelty (BERT): 0.5555669745646055
- Combined Prediction Score: 0.7802823788372526
- Mean Citation Score: 422.2789
- Max Citation Score: 484.66568
- Similarity Product: 283.2867793527222

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test