PATENT CLAIM ANALYSIS

Application Number: 15778220
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["514", "027000"]

Abstract:
This present invention relates to a complex of a glucopyranosyl derivative and L-pyroglutamic acid as a sodium dependent glucose cotransporter (SGLT) inhibitor, and preparation processes thereof, and a pharmaceutical composition containing the complex, and their uses in the manufacture of a medicament for treating diabetes and/or diabetes-related diseases.

Claim (Index 20):
A process of preparing the complex of  claim 1 , wherein the process comprises the steps of:\n (i) dissolving the compound having Formula (I-n) and L-pyroglutamic acid in a solvent; (ii) cooling the solution obtained from step (i) to precipitate a solid; and (iii) separating the solid obtained from step (ii), wherein, in step (i), the solvent is a mixture of ethanol and water at a volume ratio (1:1) to (1:2) or a mixture of isopropanol and water at a volume ratio from (1:1) to (1:2); the amount of the solvent is from 1.5 mL to 5 mL per gram of the compound having Formula I-n, the mole ratio of the compound having Formula (I-n) and L-pyroglutamic acid is from (1:3) to (1:4), and the dissolving temperature is from 70\u00b0 C. to 90\u00b0 C., in step (ii), the cooling is natural cooling at a temperature from 10\u00b0 C. to 30\u00b0 C., in step (iii), the separating is filtration under vacuum suction, wherein the filtration under vacuum suction further comprises washing the solid after separation, wherein the solid after separation is washed with a mixture of ethanol and water at a volume ratio from (1:1) to (1:2) or a mixture of isopropanol and water at a volume ratio from (1:1) to (1:2), and wherein the mixture is precooled to a temperature from \u221220\u00b0 C. to 0\u00b0 C.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 93.0
- Lexical Diversity: 1.28571
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14627693', '15804074', '13158724', '12503225', '13530645']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7903465590949378
- 35 USC 102 Novelty (BERT): 0.5156801453747578
- Combined Prediction Score: 0.7628799177229197
- Mean Citation Score: 259.12978200000003
- Max Citation Score: 287.61752
- Similarity Product: 193.4552900872517

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test