PATENT CLAIM ANALYSIS

Application Number: 15751098
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "255050"]

Abstract:
Described herein are methods of treatment of stroke and traumatic brain injury comprising administration of a CRAC channel inhibitor.

Claim (Index 41):
A method for treating stroke or traumatic brain injury in an individual in need thereof comprising administering to the individual a therapeutically effective amount of a compound having the structure of Formula (III): wherein: R 1  is X is S, O, or NR 5 ; Y is independently selected from CR 10  or N; R 2  is aryl, heteroaryl, fused aryl or fused heteroaryl; wherein aryl, heteroaryl, fused aryl or fused heteroaryl is optionally substituted with at least one R 3 ; R 3  is independently selected from H, F, D, Cl, Br, I, \u2014CN, \u2014NO 2 , \u2014OH, \u2014CF 3 , \u2014OCF 3 , \u2014OR 5 , optionally substituted C 1 -C 6 alkyl, optionally substituted C 3 -C 8 cycloalkyl, optionally substituted C 1 -C 6 heteroalkyl, C 1 -C 6 haloalkyl, optionally substituted C 2 -C 8 heterocycloalkyl, optionally substituted aryl, optionally substituted O-aryl, and optionally substituted heteroaryl; R 5  is selected from H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 8 cycloalkyl, phenyl, and benzyl; R 9  and R 10  are each independently selected from H, D, optionally substituted C 1 -C 6 alkyl, halogen, C 1 -C 6  alkylcarbonyl, or CF 3 ; R 12  is selected from CN, \u2014OR 5 , optionally substituted C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, and optionally substituted C 3 -C 8 cycloalkyl, optionally substituted aryl, optionally substituted O-aryl, and optionally substituted heteroaryl; or a pharmaceutically acceptable salt, or pharmaceutically acceptable solvate thereof.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 88.0
- Lexical Diversity: 1.11111
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13553726', '13975238', '14730119', '12192812', '13085324']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7642980202460617
- 35 USC 102 Novelty (BERT): 0.5415372537179222
- Combined Prediction Score: 0.7420219435932478
- Mean Citation Score: 369.913778
- Max Citation Score: 378.0709
- Similarity Product: 278.7389794474959

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test