PATENT CLAIM ANALYSIS

Application Number: 15902255
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "450000"]

Abstract:
The present invention provides a vesicle, a conjugate, a composition comprising the vesicle or the conjugate, for use in delivering a drug to the brain, and a method for administering the same. The composition of the present invention is a composition for administration to a subject according to a dosing regimen, comprising a carrier for drug delivery, wherein the dosing regimen comprises administering the composition to a subject who has been fasted or caused to have hypoglycemia and inducing an increase in blood glucose level in the subject, and the carrier is modified at the outer surface thereof with a GLUT1 ligand.

Claim (Index 27):
A method of delivering a drug to at least one of a brain and cerebrovascular endothelial cells in a subject, comprising:\n lowering blood glucose level in the subject; and subsequently administering a drug to the subject whose blood glucose level has been lowered and increasing blood glucose level in the subject, wherein the drug is included in a carrier having an outer surface modified with a GLUT1 ligand.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 1.98214
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15038374', '15575716', '14106078', '10541304', '13374046']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6853183654656154
- 35 USC 102 Novelty (BERT): 0.5961264242881059
- Combined Prediction Score: 0.6763991713478645
- Mean Citation Score: 301.87319800000006
- Max Citation Score: 550.83795
- Similarity Product: 442.1055079887986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test