PATENT CLAIM ANALYSIS

Application Number: 15764317
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["424", "009322"]

Abstract:
The invention relates to a ligand compound having a structure A-B-C, wherein (a) A represents a mono- or polyphosphorylated amino acid linked to part B by its amino group to form an amide bond; B represents (i) a carboxylic acid, and (ii) an amino acid or peptidyl group of 2-10 amino acids, an alkyl or alkenyl group comprising 1-26 carbon atoms, a polyethylene glycol group comprising 1-26 carbon atoms or a combination thereof covalently linked to the carboxylic acid; and C represents a hydrophilic group covalently linked to the group of B (ii) or (b) A represents a mono-or polyphosphorylated amino acid linked to B by its carboxylic acid to form an amide bond; B represents an amino acid or peptidyl group of 2-10 amino acids, an amino substituted alkyl or alkenyl group comprising 1-26 carbon atoms, an amino substituted polyethylene glycol group comprising 1-26 carbon atoms or a combination thereof covalently linked to A by their amino group; C represents a hydrophilic group covalently linked to the group of B. The invention further relates to a coated metal nanoparticle such as super paramagnetic iron oxide nanoparticle (SPIONs) coated with a plurality of the aforementioned ligands and a method of producing thereof.

Claim (Index 14):
Method of producing a coated metal nanoparticle according to any one of  claims 10 - 12  comprising:\n (a) providing a core metal nanoparticle and a plurality of ligand compounds according to any one of  claims 1 - 9 ; and \n (b) combining the core metal nanoparticle and the plurality of ligand compounds under conditions that allow the formation of the coated metal nanoparticle according to any one of  claims 10 - 12 .

Metadata:
- Claim Count in Document: 20.0
- Percentile: 90.0
- Lexical Diversity: 2.97368
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['13716109', '13771479', '12440516', '13969362', '12232818']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.719666289899623
- 35 USC 102 Novelty (BERT): 0.5022512830012023
- Combined Prediction Score: 0.697924789209781
- Mean Citation Score: 242.3747
- Max Citation Score: 248.82584
- Similarity Product: 170.50892629570006

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test