PATENT CLAIM ANALYSIS

Application Number: 15762363
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["800", "017000"]

Abstract:
The present invention relates to genetically-edited swine comprising an introgressed heterologous nucleic acid sequence in the RELA gene. In particular it relates to genetically-edited swine comprising an introgressed warthog allele in the RALA gene of domestic pigs. The invention also related to methods of producing such swine, and cells derived from swine having such introgressed sequences.

Claim (Index 42):
The method of  claim 24  comprising the steps of:\n providing a domestic pig zygote; \n introducing into said zygote a pair of cooperating site-specific nucleases, the nucleases being adapted to target the RELA gene in the region of within 20 bp of the sequence encoding T448A and introduce a double stranded break; \n introducing a template nucleic acid comprising a heterologous nucleic acid comprising a sequence encoding the corresponding warthog RELA haplotype flanked by sequences homologous to the genomic RELA sequence of the pig; \n incubating said zygote under suitable conditions to permit cutting of the genome by the site-specific nuclease and introgression of the heterologous nucleic acid by homology-directed repair; and \n generating a pig from said zygote.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 90.0
- Lexical Diversity: 1.5
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14427776', '14263446', '14907069', '15128595', '13836860']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6062326232019992
- 35 USC 102 Novelty (BERT): 0.5428008329773314
- Combined Prediction Score: 0.5998894441795325
- Mean Citation Score: 323.4126320000001
- Max Citation Score: 444.29813
- Similarity Product: 309.5073814771652

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test