PATENT CLAIM ANALYSIS

Application Number: 15974171
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "351000"]

Abstract:
Disclosed are novel compounds having the structure of Formula (I): which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and/or alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of a compound of Formula (I) and methods of using the compounds of Formula (I) in the treatment of addiction to a dopamine-producing agent.

Claim (Index 1):
A compound of Formula (II): wherein:\n R 1  is hydrogen, \u2014CH 2 OH, \u2014CH 2 OP(O)(OR 20 )(OR 21 ), or optionally substituted C 1-6  alkyl; \n R 2  is hydrogen, halo, optionally substituted lower C 1-6  alkyl, or optionally substituted cycloalkyl; \n each of R 3 , R 4 , R 5 , R 6 , R 9 , R 10 , R 11 , R 12  and R 13  is independently hydrogen, hydroxyl, \u2014OP(O)(OR 20 )(OR 21 ), \u2014CH 2 OH, \u2014CH 2 OP(O)(OR 20 )(OR 21 ), optionally substituted alkyl, optionally substituted alkylene, optionally substituted alkynyl, optionally substituted alkoxy, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, optionally substituted heteroaralkyl, optionally substituted heterocyclyl, aminocarbonyl, acyl, acylamino, \u2014O\u2014(C 1  to C 6 -alkyl)-O\u2014(C 1  to C 6 -alkyl), cyano, halo, \u2014SO 2 NR 24 R 25 ; or \u2014NR 24 R 25 ; \n R 7  is hydrogen or optionally substituted C 1-6  alkyl; \n each of R 20  and R 21  is independently Na + , Li + , K + , hydrogen, C 1-6  alkyl; or R 20  and R 21  can be combined to represent a single divalent cation Zn 2+ , Ca 2+ , or Mg 2+ ; and \n each of R 24  and R 25  is independently chosen from hydrogen or C 1-6  alkyl or when combined together with the nitrogen to which they are attached form a heterocycle; or \n a pharmaceutically acceptable salt, ester, single stereoisomer, mixture of stereoisomers, or tautomer thereof.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 93.0
- Lexical Diversity: 1.66667
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15476569', '14659042', '13537536', '13966029', '13791422']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8047675395144073
- 35 USC 102 Novelty (BERT): 0.5843233513776804
- Combined Prediction Score: 0.7827231207007346
- Mean Citation Score: 451.44146
- Max Citation Score: 464.60397
- Similarity Product: 445.46104855665567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test