PATENT CLAIM ANALYSIS

Application Number: 15880007
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["506", "009000"]

Abstract:
This invention provides methods for amplifying, detecting, measuring, and identifying miRNAs from biological samples, particularly limited amounts of a biological sample. miRNAs that are differentially expressed in tumor samples and normal tissues are useful as cancer biomarkers for cancer diagnostics.

Claim (Index 1):
A method of detecting differentially expressed miRNA in a nasopharyngeal carcinoma biological sample, comprising:\n a) obtaining a nasopharyngeal carcinoma biological sample; b) isolating RNA from the biological sample; c) producing cDNAs from an isolated miRNA population from the biological sample; d) transcribing the cDNAs to produce miRNA targets; e) hybridizing the miRNA targets to an array of complementary probes for miRNA; f) detecting the miRNA targets hybridized to the probe array; and g) identifying differentially expressed miRNAs compared to a control, wherein the differentially expressed miRNAs include one or more of miR-29c, miR-29a, miR-29b, miR-34c, miR-34b, miR-212, miR-216, miR-217, miR-151, and miR-192 miRNAs.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 86.0
- Lexical Diversity: 1.31429
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13129289', '13387314', '13032377', '14592699', '12310509']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.636086675117367
- 35 USC 102 Novelty (BERT): 0.5315998101295962
- Combined Prediction Score: 0.62563798861859
- Mean Citation Score: 348.111664
- Max Citation Score: 367.98816
- Similarity Product: 266.4379834629822

Labels:
- Claim Label 101: 0
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test