PATENT CLAIM ANALYSIS

Application Number: 15979041
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["514", "402000"]

Abstract:
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.

Claim (Index 44):
The method of  claim 43  wherein the drug therapy comprises the administration of bisantrene and wherein the drug delivery system is selected from the group consisting of:\n (a) oral dosage forms; \n (b) nanocrystals; \n (c) nanoparticles; \n (d) cosolvents; \n (e) slurries; \n (f) syrups; \n (g) bioerodible polymers; \n (h) liposomes; \n (i) slow-release injectable gels; \n (j) microspheres; \n (k) amphiphilic block copolymer systems; \n (l) emulsion vehicles comprising an emulsion of \u03b1-tocopherol stabilized by biocompatible surfactants; \n (m) biodegradable polymer compositions containing phosphorus and desaminotyrosyl L-tyrosine linkages in the polymer backbone; \n (n) substantially anhydrous injectable semi-solid compositions comprising a water immiscible fatty acid matrix and a cytostatic agent; \n (o) lipophilic vehicles; \n (p) pH-dependent carriers that include a compound that includes at least one ionizable group; \n (q) pH-dependent carriers that include a monocarboxylic acid having at least 8 carbons and less than about 10% by weight of zwitterionic phospholipids; \n (r) liposomes comprising the bisantrene or the derivative or analog thereof followed by administration of a lipid nanoparticle comprising a triggering agent; and \n (s) nonpegylated liposomes.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 93.0
- Lexical Diversity: 1.31579
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14907728', '14907729', '13817096', '14753911', '14245738']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7424759879162982
- 35 USC 102 Novelty (BERT): 0.5349518571973405
- Combined Prediction Score: 0.7217235748444024
- Mean Citation Score: 267.787678
- Max Citation Score: 348.62634
- Similarity Product: 237.7014623214769

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test