PATENT CLAIM ANALYSIS

Application Number: 15989809
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["424", "489000"]

Abstract:
The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of proteoglycans than the actual disc material ( 6 ) itself. To this end, there has been developed a technique to remove the nucleus pulposus and retool the morphology of the nucleus pulposus to create a powder material ( 10 ) that is dry and can be stored at room temperature for long periods of time. This powder ( 10 ) can then be reconstituted with a variety of fluids, the most suitable being normal saline or lactated ringers to form a flowable mixture ( 20 ).

Claim (Index 1):
An aqueous spinal disc regenerative composition suitable for injection, wherein the aqueous composition comprises a rehydrated micronized freeze-dried nucleus pulposus wherein the rehydrated micronized freeze-dried nucleus pulposus is\n a hydrated composition comprising freeze-dried micronized nucleus pulposus in a fluid, produced by a method consisting of: (i) providing normal human cadaveric intervertebral discs; (ii) separating the nucleus pulposus from the annulus fibrosus of the normal human cadaveric intervertebral disc; (iii) drying the nucleus pulposus; (iv) micronizing the dried nucleus pulposus by pulverizing in a cryomill at low temperature into particles sized less than 400 microns; (v) freeze-drying the nucleus pulposus, wherein said freeze-drying occurs during step (iii), between steps (iii) and (iv), and/or after step (iv); and then (vi) mixing; the freeze-dried micronized nucleus pulposus with the fluid thereby producing the hydrated composition.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 1.4625
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14334318', '14697778', '14697790', '15474450', '15474415']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7680538339342395
- 35 USC 102 Novelty (BERT): 0.5336950974930457
- Combined Prediction Score: 0.7446179602901202
- Mean Citation Score: 325.288334
- Max Citation Score: 368.477
- Similarity Product: 355.64903934067485

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test