PATENT CLAIM ANALYSIS

Application Number: 15865678
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["514", "017700"]

Abstract:
The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/or traumatic brain injury.

Claim (Index 1):
A method for treating a traumatic brain injury in a subject comprising administering a therapeutically effective amount of an oligopeptide having the formula: A 1 -A 2 -A 3 -A 4 -A 5 -A 6 -A 7 -A 8  (SEQ ID NO:1) wherein\n A 1  is selected from the group consisting of aspartic acid, glutamic acid, alanine, and glycosylated forms thereof; A 2  is selected from the group consisting of arginine, histidine, lysine, and glycosylated forms thereof; A 3  is selected from the group consisting of valine, alanine, isoleucine, leucine, and glycosylated forms thereof; A 4  is selected from the group consisting of tyrosine, phenylalanine, tryptophan, and glycosylated forms thereof; A 5  is selected from the group consisting of isoleucine, valine, alanine, leucine, and glycosylated forms thereof; A 6  is selected from the group consisting of histidine, arginine, lysine, and glycosylated forms thereof; A 7  is selected from the group consisting of proline, glycine, serine, and glycosylated forms thereof; and A 8  can be present or absent, wherein when A 8  is present, A 8  is selected from the group consisting of serine, threonine, hydroxyproline, and glycosylated forms thereof,

Metadata:
- Claim Count in Document: 4.0
- Percentile: 86.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15401944', '15134073', '15691586', '14801557', '15360698']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7946647203331011
- 35 USC 102 Novelty (BERT): 0.5609483583708336
- Combined Prediction Score: 0.7712930841368744
- Mean Citation Score: 372.30146
- Max Citation Score: 444.34255999999993
- Similarity Product: 377.4078513429261

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test