PATENT CLAIM ANALYSIS

Application Number: 15763095
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-08
Patent Classification: ["514", "171000"]

Abstract:
Bruton's tyrosine kinase (Btk) inhibitors have the following Formula (I):

Claim (Index 9):
A compound selected from the group consisting of (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl), (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(3-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (S)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-chloro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chloro-5-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-cyclopropylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(3-(2-thioxo-3-(4-(m-tolyloxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(3-fluoro-4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-((1-acryloylpiperidin-4-yl)methyl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-((1-acryloylpiperidin-4-yl)methyl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-(p-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-(4-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R,E)-3-(3-chloro-4-phenoxyphenyl)-1-(1-(3-morpholinoacryloyl)pyrrolidin-3-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-((1-acryloylpyrrolidin-2-yl)methyl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R,E)-3-(3-chloro-4-phenoxyphenyl)-1-(1-cinnamoylpyrrolidin-3-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-3-(3-chloro-4-phenoxyphenyl)-1-(1-(vinylsulfonyl)pyrrolidin-3-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-ethoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-isopropoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3-chlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(3-methyl-4-phenoxyphenyl)-2-oxo-2,3-dihydro-1H-imidazo [4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-methacryloylpyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R,E)-1-(1-cinnamoylpyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-(1-acryloylpiperidin-4-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(phenylthio)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acetylpyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-(but-2-ynoyl)pyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(4-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(4-(trifluoromethyl)phenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3,4-dichlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(phenylthio)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3,5-difluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3,4-dimethoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(4-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(4-(trifluoromethyl)phenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3,4-dichlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-isopropoxyphenoxy)-3-methylphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c] pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-methyl-4-(m-tolyloxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo [4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-fluoro-4-(3-isopropoxyphenoxy) phenyl)-2-oxo-2,3-dihydro-1H-imidazo [4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-fluoro-4-(m-tolyloxy) phenyl)-2-oxo-2,3-dihydro-1H-imidazo [4,5-c]pyridin-1-yl)phenyl)acrylamide, (N-(3-(3-(4-(3-chlorophenoxy)-3-fluorophenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl) acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2,3-dimethylphenoxy) phenyl)-1H-imidazo[4,5-c] pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-(3-isopropoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-(3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-(3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-(3-fluoro-2-methylphenoxy) phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-(3-cyclopropoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-fluoro-2-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2,3-dimethylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-chloro-2-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2,3-difluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2,3-difluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-methoxyphenoxy)-3-methylphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl) phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chloro-2-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-chloro-2-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, ((R)-1-(1-acryloylpyrrolidin-3-yl)-2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridine-4-carbonitrile, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-methoxy-3-methylphenoxy) phenyl)-1H-imidazo[4,5-c] pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-methoxy-3-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-methoxy-3-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-chlorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(4-(3-(trifluoromethoxy)phenoxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-chloro-5-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(3-chloro-4-phenoxyphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-(3-chlorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-(3-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(3-(p-tolyloxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-(3-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-fluoro-2-methylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(4-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(4-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(4-chlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(o-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-isopropoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-(3-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-(3-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(3-(o-tolyloxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-(2-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-fluoro-4-(3-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, 1-(1-acryloylpyrrolidin-3-yl)-3-(3-methyl-4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, 1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-methoxyphenoxy)-3-methylphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, N-(3-(3-(3-fluoro-4-phenoxyphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-fluoro-4-(3-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-fluoro-4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, N-(3-(3-(3-(3-chloro-2-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-(3-chloro-2-fluorophenoxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, N-(3-(3-(4-(2,3-dichlorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2,3-dichlorophenoxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2,3-dichlorophenoxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chloro-2-fluorophenoxy)-3-fluorophenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-chloro-3-fluorophenoxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-chloro-3-fluorophenoxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(pyridin-2-yloxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(3-fluoro-4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-chlorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(3-chloro-4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(3-chloro-4-(m-tolyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)cinnamamide, N-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)methacrylamide, N-(3-(3-(3-chloro-4-(4-(trifluoromethyl)phenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-(trifluoromethoxy)phenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-ethoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-isopropylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, 4-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenoxy)-N-methylpicolinamide, N-(3-(2-oxo-1-(4-phenoxyphenyl)-1H-imidazo[4,5-b]pyridin-3(2H)-yl)phenyl)acrylamide, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)phenyl)acrylamide, (R)-3-(1-acryloylpyrrolidin-3-yl)-1-(4-phenoxyphenyl)-1H-imidazo[4,5-b]pyridin-2(3H)-one, N-(3-(2-oxo-1-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)acrylamide, (R)-3-(1-acryloylpiperidin-3-yl)-1-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-(4-(trifluoromethyl)phenoxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(4-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(2,3-difluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3,4-difluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3,5-difluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-chloro-2-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-chloro-5-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3,5-dichlorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3,4-dimethoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-fluoro-4-phenoxyphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chloro-2-fluorophenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-chloro-2-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-chloro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-fluoro-2-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-fluoro-2-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-fluoro-3-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chloro-2-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-fluoro-2-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-fluoro-3-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(3-methoxy-2-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-methoxy-2-methylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(3-chloro-4-(m-tolyloxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-(3-isopropoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-fluorophenoxy)-3-methylphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(2,3-dimethylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-(2,3-dimethylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-chlorophenoxy)-3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-chloro-2-methylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-7-chloro-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(3-(m-tolyloxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(3-isopropylphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-(3-chlorophenoxy)-3-methylphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-methacryloylpyrrolidin-3-yl)-3-(3-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-(phenylthio)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3,4-dichlorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(4-chloro-3-fluorophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(3-fluoro-4-methoxyphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(4-cyanophenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(4-methoxy-3-methylphenoxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, 1-(1-acryloylpyrrolidin-3-yl)-3-(4-(pyridin-4-yloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 1-(1-acryloylpyrrolidin-3-yl)-3-(4-(pyridazin-3-yloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(2-oxo-3-(4-((2,4,5-trifluorobenzyl)oxy) phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(4-(pyridin-2-ylmethoxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(benzyloxy)-3-chlorophenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((3,4-dichlorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((2,4-difluorobenzyl)oxy)phenyl)-1H-imidazo [4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((3,4-difluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((2,4-difluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((2-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((3,5-difluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((2,4-dichlorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((2,5-difluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((2-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(pyridin-2-ylmethoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((3,4-difluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((3,4-dichlorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((2-fluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(3-fluoro-4-((2-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((3,4-dichlorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((3,5-difluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2,5-difluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((4-chlorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((3-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(benzyloxy)-3-chlorophenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2-methylbenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2,6-difluorobenzyl oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2,6-difluorobenzyl)oxy)-3-fluorophenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2,4-dichlorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((3-chlorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2-chlorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(4-((2-(trifluoromethyl)benzyl)oxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-(benzyloxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-(benzyloxy)-3-fluorophenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (S)-1-(1-acryloylpyrrolidin-3-yl)-3-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, (S)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(benzyloxy)-3-fluorophenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, N-(3-(3-(4-((3-chloro-2-fluorobenzyl)oxy)-3-fluorophenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (N-(3-(3-(4-(benzyloxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((3,4-difluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(2-oxo-3-(4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(3-chloro-4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-((4-chloro-2-fluorobenzyl)oxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-((4-chloro-2-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, ((R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(benzyloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-((4-fluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4-((2,4-difluorobenzyl)oxy)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, 4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-(4-fluorobenzyl)benzamide, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(morpholine-4-carbonyl)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-(3-(trifluoromethyl)phenyl)benzamide, 4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-(3-methoxybenzyl)benzamide, N-(3-(3-(4-(morpholine-4-carbonyl)phenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, 4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-phenylbenzamide, 4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-(m-tolyl)benzamide, (R)-4-(1-(1-acryloylpyrrolidin-3-yl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)-N-(3-methoxybenzyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-2-methoxybenzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-3-chlorobenzamide, N-(3-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-4-(tert-butyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1,2-dihydro-3H-imidazo[4,5-c]pyridin-3-yl)phenyl)-2-(trifluoromethyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1,2-dihydro-3H-imidazo[4,5-c]pyridin-3-yl)phenyl)-4-(trifluoromethyl)benzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-4-methoxybenzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-3-fluorobenzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-3-methoxybenzamide, N-(4-(1-(3-acrylamidophenyl)-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)phenyl)-3-methylbenzamide, N-(3-(3-(3\u2032-methyl-[1,1\u2032-biphenyl]-4-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, N-(3-(3-([1,1\u2032-biphenyl]-4-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c] pyridin-1-yl)phenyl)acrylamide, N-(3-(3-(4\u2032-methyl-[1,1\u2032-biphenyl]-3-yl)-2-oxo-2,3-dihydro-1H-imidazo [4,5-c]pyridin-1-yl)phenyl)acrylamide, (R) 1-(1-acryloylpyrrolidin-3-yl)-3-(2\u2032-methyl-[1,1\u2032-biphenyl]-3-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(2-fluoro-4-methoxy-[1,1\u2032-biphenyl]-4-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-4-yl)-3-(2\u2032,4\u2032-dichloro-[1,1\u2032-biphenyl]-4-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4\u2032-methyl-[1,1\u2032-biphenyl]-4-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-3-([1,1\u2032-biphenyl]-3-yl)-1-(1-acryloylpyrrolidin-3-yl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, N-(3-(3-(4-cyclopropylphenyl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)acrylamide, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methoxy-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-7-ethoxy-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-((1-(but-2-ynoyl)pyrrolidin-2-yl)methyl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-((1-acryloylpyrrolidin-2-yl)methyl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-(but-2-ynoyl)piperidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-(but-2-ynoyl)pyrrolidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-7-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one, (E)-N-(3-(6-amino-8-oxo-7-(4-phenoxyphenyl)-7H-purin-9(8H)-yl)phenyl)-4-(cyclopropyl(methyl)amino)-N-methylbut-2-enamide, (R)-1-(1-(but-2-ynoyl)piperidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-7-methyl-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (S,Z)-9-(1-acryloylpyrrolidin-3-yl)-6-(hydroxyimino)-7-(4-phenoxyphenyl)-7,9-dihydro-1H-purin-8(6H)-one, 1-(1-Acryloyl-pyrrolidin-2-ylmethyl)-3-(4-phenoxy-phenyl)-1,3-dihydro-imidazo[4,5-c]pyridin-2-one, (S,Z)-1-(1-acryloylpyrrolidin-3-yl)-N\u2032-hydroxy-2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridine-4-carboximidamide, 4,4-dimethyl-2-{2-[2-oxo-3-(4-phenoxy-phenyl)-2,3-dihydro-imidazo[4,5-c]pyridin-1-ylmethyl]-pyrrolidine-1-carbonyl})-pent-2-enenitrile, (R)-1-(1-acryloylpyrrolidin-3-yl)-2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridine-7-carbonitrile, (R)-1-(1-acryloylpyrrolidin-3-yl)-4-methoxy-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-4-hydroxy-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-7-chloro-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-chloro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpiperidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R,E)-1-(1-(4-(cyclopropyl(methyl)amino)but-2-enoyl)pyrrolidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R,E)-1-(1-(4-(cyclopropyl(methyl)amino)but-2-enoyl)piperidin-3-yl)-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-4-nitro-3-(4-phenoxyphenyl)-1H-benzo[d]imidazol-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-benzo[d]imidazol-2(3H)-one, (R)-1-(1-acryloylpyrrolidin-3-yl)-3-(4-(2-fluoro-3-methoxyphenoxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 2-oxo-2-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)piperidin-1-yl)acetic acid, 3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl) cyclohexanecarboxylic acid, and 2-oxo-2-(3-(2-oxo-3-(4-phenoxyphenyl)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)piperidin-1-yl)acetamide.

Metadata:
- Claim Count in Document: 9.0
- Percentile: 90.0
- Lexical Diversity: 1.14286
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13805471', '13780557', '15530681', '14376307', '15410716']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8423793325154958
- 35 USC 102 Novelty (BERT): 0.5412356985320926
- Combined Prediction Score: 0.8122649691171555
- Mean Citation Score: 394.870806
- Max Citation Score: 395.57306
- Similarity Product: 336.53721110985987

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test