PATENT CLAIM ANALYSIS

Application Number: 16228091
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["424", "205100"]

Abstract:
A method of producing a picornavirus-like particle (PVLP) in a plant is provided. The method comprises introducing a first nucleic acid and a second nucleic acid into the plant, portion of the plant, or a plant cell. The first nucleic acid comprising a first regulatory region active in the plant operatively linked to a nucleotide sequence encoding a polyprotein. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding one or more protease. The plant, portion of the plant, or plant cell is incubated under conditions that permit the expression of the nucleic acids, thereby producing the PVLP. A PVLP comprising the polyprotein is also provided.

Claim (Index 21):
A plant extract comprising an Enterovirus-like particles (EVLPs) produced by a method comprising:\n a) introducing into a plant, portion of a plant, or a plant cell a first nucleic acid comprising a first regulatory region active in the plant operatively linked to a nucleotide sequence encoding an Enterovirus polyprotein, wherein the Enterovirus polyprotein consists of Enterovirus 71 polyprotein P1; b) introducing a second nucleic acid comprising a second regulatory region active in the plant and operatively linked to a second nucleotide sequence encoding one or more Enterovirus 71 3C or 3CD protease into the plant, portion of the plant, or plant cell; c) incubating the plant, portion of the plant, or plant cell under conditions that permit expression of the first and second nucleic acid to produce the Enterovirus 71 polyprotein P1 and the one or more Enterovirus 71 3C or 3CD protease, the Enterovirus 71 polyprotein P1 being processed into structural proteins VP1, VP3, and VP0 or VP1, VP2, VP3 and VP4, thereby producing the EVLP; and d) harvesting the plant, portion of the plant, or plant cell to produce the plant extract.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 98.0
- Lexical Diversity: 2.5
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14426019', '15964211', '15964198', '14402495', '15307926']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7407639458604871
- 35 USC 102 Novelty (BERT): 0.7527958475940477
- Combined Prediction Score: 0.7419671360338432
- Mean Citation Score: 558.1544719999998
- Max Citation Score: 869.9621
- Similarity Product: 846.1381910110235

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test