PATENT CLAIM ANALYSIS

Application Number: 16430244
Application Type: Utility
Filing Date: 2019-06
Publication Date: 2019-09
Patent Classification: ["525", "538000"]

Abstract:
The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.

Claim (Index 2):
A linear polyphosphazene-drug conjugate compounds represented by the following chemical formula 2: wherein, in chemical formula 2, n is an integer from 3 to 300;\n MPEG represents methoxy poly(ethylene glycol); \n S is an amino-ethanol spacer group; \n L is a cis-aconitic acid anhydride linker to connect the spacer group and drug molecule D, wherein drug molecule D is (trans-(\u00b1)-1,2-diaminocyclohexane)platinum(II); \n x and y are 0; and \n z is 1.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 100.0
- Lexical Diversity: 1.35088
- Patent Class: 525.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15125543', '16430230', '13821228', '15296414', '13058320']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7424859674898144
- 35 USC 102 Novelty (BERT): 0.562740563019516
- Combined Prediction Score: 0.7245114270427846
- Mean Citation Score: 303.470876
- Max Citation Score: 470.66663
- Similarity Product: 387.9132408893907

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test