PATENT CLAIM ANALYSIS

Application Number: 15985334
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-02
Patent Classification: ["514", "002000"]

Abstract:
The present invention describes compositions and methods for treating cardiovascular disease and myocardial infarction using dipeptidyl peptidase inhibitors. Also provided are methods for increasing natriuretic peptide function by administering one or more analogues of B type natriuretic peptide that provide increased stability in the presence of prolyl-specific dipeptidyl peptidases.

Claim (Index 1):
A method for the treatment of cardiovascular disease comprising\n a) contacting a sample from a subject with a first antibody selected to bind biologically active forms of the natriuretic peptide of interest contacting the sample with a second antibody selected to bind all biologically active and biologically inactive forms of the natriuretic peptide of interest and performing an assay in which the signal depends upon the selected antibody specifically binding to a biologically active form of the natriuretic peptide of interest, but not specifically binding to a biologically inactive form of the natriuretic peptide of interest; and b) administering a therapeutically effective amount of a dipeptidyl peptidase inhibitor to said subject when the presence of said biologically active form of said natriuretic peptide is present, and wherein said administration preserves the presence of said biologically active form of said natriuretic peptide.

Metadata:
- Claim Count in Document: 22.0
- Percentile: 93.0
- Lexical Diversity: 1.18605
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15293262', '10938760', '10827919', '15269423', '13132493']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.784692459028465
- 35 USC 102 Novelty (BERT): 0.5135716111945069
- Combined Prediction Score: 0.7575803742450692
- Mean Citation Score: 250.32855
- Max Citation Score: 362.18124
- Similarity Product: 275.69253649252653

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test