PATENT CLAIM ANALYSIS

Application Number: 16005245
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["424", "179100"]

Abstract:
Provided are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.

Claim (Index 28):
A compound represented by Formula I: wherein: Ar is an optionally substituted phenyl; G is a glucuronic acid moiety or wherein R 3  is hydrogen or a carboxyl protecting group, and each R 4  is independently hydrogen or a hydroxyl protecting group;\n Q is an amine, carbonyl, hydroxylamine, alkyne, or alkene; \n W is \u2014C(O)\u2014, \u2014C(O)NR\u2032\u2014, \u2014C(O)O\u2014, \u2014SO 2 NR\u2032\u2014, \u2014P(O)R\u2033NR\u2032\u2014, \u2014SONR\u2032\u2014, or \u2014PO 2 NR\u2032\u2014, in each case where the C(O), S, or P is directly bound to the phenyl ring, and R\u2032 and R\u2033 are each independently hydrogen, (C 1 -C 8 )alkyl, (C 3 -C 8 )cycloalkyl, (C 1 -C 8 )alkoxy, (C 1 -C 8 )alkylthio, mono- or di-(C 1 -C 8 )alkylamino, (C 3 -C 20 )heteroaryl or (C 6 -C 20 )aryl; \n Z is hydrogen, (C 1 -C 8 )alkyl, halogen, cyano or nitro; \n n is an integer of 1 to 3, and when n is an integer of 2 or more, each of the Z(s) are the same as or different from each other; and \n R 1  and R 2  are each independently hydrogen, (C 1 -C 8 )alkyl, or (C 3 -C 8 )cycloalkyl; \n wherein either:\n A) L is an alkylene chain having 1 to 50 carbon atoms and satisfies at least one of the following (i) to (iv):\n (i) the alkylene includes at least one unsaturated bond, \n (ii) the alkylene includes at least one heteroarylene, \n (iii) at least one carbon atom of the alkylene is replaced with one or more heteroatoms selected from nitrogen (N), oxygen (O), and sulfur (S), and phosphorus (P), or \n (iv) the alkylene is substituted with one or more alkyls having 1 to 20 carbon atoms; or \n \n B) L includes at least one isoprenyl derivative unit represented by Formula A:

Metadata:
- Claim Count in Document: 71.0
- Percentile: 94.0
- Lexical Diversity: 1.90244
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14898932', '15276209', '15276231', '11996009', '13274212']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7796070770728047
- 35 USC 102 Novelty (BERT): 0.6050058426328723
- Combined Prediction Score: 0.7621469536288115
- Mean Citation Score: 397.211968
- Max Citation Score: 564.2984
- Similarity Product: 469.4700433383942

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test