PATENT CLAIM ANALYSIS

Application Number: 15981915
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["536", "029200"]

Abstract:
The present invention relates to pyrazolotriazolyl nucleoside analogues, oligonucleotide comprising them, and uses thereof. Further the invention relates to a method for reducing gene expression in a cell comprising transfecting the cell with such an oligonucleotide.

Claim (Index 3):
The oligonucleotide of  claim 1 , comprising one or more 9-adeninyl PT nucleotide analogues, each independently of the general formula II, wherein R 1  is and R 4  each independently is H, halogen, (C 1 -C 2 )alkyl, \u2014O\u2014(C 1 -C 2 )alkyl, \u2014S\u2014(C 1 -C 2 )alkyl, \u2014CO\u2014H, \u2014CO\u2014(C 1 -C 2 )alkyl, or \u2014NR 8 R 9 , wherein R 8  and R 9  are each independently H or (C 1 -C 2 )alkyl, provided that at least one of R 8  and R 9  is not H; R 2  is absent; R 3  is \u2014NH-benzoyl; R 5  is halogen or \u2014OR 11 ; R 6  is \u2014OR 11 ; R 7  is \u2014OR 11 , a monophosphate moiety, or a phosphate linking moiety; and R 11  each independently is (C 1 -C 4 )alkyl, (C 1 -C 4 )alkylene-OH, (C 1 -C 4 )alkylene-OCH 3 , (C 1 -C 4 )alkylene-SH, (C 1 -C 4 )alkylene-SCH 3 , or (C 1 -C 4 )alkylene-NH 2 .

Metadata:
- Claim Count in Document: 11.0
- Percentile: 93.0
- Lexical Diversity: 1.33333
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14403580', '09528110', '09565699', '14403581', '12192581']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6126759234550829
- 35 USC 102 Novelty (BERT): 0.596834462298308
- Combined Prediction Score: 0.6110917773394055
- Mean Citation Score: 321.328756
- Max Citation Score: 520.20465
- Similarity Product: 493.79352679436806

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test