PATENT CLAIM ANALYSIS

Application Number: 15918626
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "04400A"]

Abstract:
The subject invention pertains to biomarkers for identifying BC in a subject. The biomarkers presented herein include miRNAs, particularly, a combination of miRNAs. The invention demonstrates that the specific miRNAs are increased body fluid, particularly, urine, from a subject compared to that of a control. Accordingly, the levels of specific mRNAs, in a body fluid, particularly, urine, from a subject is used to diagnose BC in a subject. The invention also provides kits and reagents to conduct assays to quantify biomarkers described herein. The invention further provides methods of treating and/or managing BC in a subject.

Claim (Index 9):
The method of  claim 6 , wherein treating BC in the subject comprises administering to the subject: a) one or more antisense miRNAs that target one or more miRNAs from Panel 25 that are upregulated in BC, b) one or more miRNAs from Panel 25 that are downregulated in BC, or a combination of a) and b).

Metadata:
- Claim Count in Document: 14.0
- Percentile: 90.0
- Lexical Diversity: 2.15385
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15300808', '13746589', '14755261', '15852128', '15318646']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6385548764560047
- 35 USC 102 Novelty (BERT): 0.5150646370940198
- Combined Prediction Score: 0.6262058525198062
- Mean Citation Score: 209.242642
- Max Citation Score: 225.11575
- Similarity Product: 128.3213564855158

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test