PATENT CLAIM ANALYSIS

Application Number: 16133322
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-08
Patent Classification: ["424", "451000"]

Abstract:
The present invention is directed to a System characterization of NASH that combines Modeling and Biomarkers, enabling pharmaceutical compositions and methods of treatment that relate to the inhibition, resolution and/or prevention of Non Alcoholic Fatty Liver Disease (NAFLD) and Non Alcoholic Steatohepatitis (NASH). Said conditions are Liver related complications among the array of manifestations of metabolic syndromes, including Type 2 diabetes, hyperlipidemia, weight gain, abdominal obesity, insulin resistance, hypertension, atherosclerosis, fatty liver diseases and certain chronic inflammatory states that lead to these manifestations, among others. In additional aspects, the present invention relates to compositions and methods which may be used to treat, inhibit or reduce the likelihood of NASH and NAFLD complications in patients with hepatitis viral infections, including Hepatitis B and Hepatitis C viral infections, as well as the secondary disease states and/or conditions which are often associated with such viral infections, including hepatic steatosis (steatohepatitis), cirrhosis, fatty liver and hepatocellular cancer, metabolic syndrome complications including cardiovascular diseases, neurodegenerative diseases and premature ageing, among other disease states or conditions.

Claim (Index 78):
The method according to  claim 73 , wherein the wCombLiver signal, wCombBiopsy Predict signal, FS index and/or CV index is calculated using a programmable spreadsheet or a website application.

Metadata:
- Claim Count in Document: 35.0
- Percentile: 97.0
- Lexical Diversity: 1.78571
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14002642', '15162941', '15624275', '14677044', '13754855']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7466992834705669
- 35 USC 102 Novelty (BERT): 0.5665393754161224
- Combined Prediction Score: 0.7286832926651226
- Mean Citation Score: 399.312976
- Max Citation Score: 502.13965
- Similarity Product: 300.6824213860661

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test