PATENT CLAIM ANALYSIS

Application Number: 15752000
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-08
Patent Classification: ["514", "210180"]

Abstract:
Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

Claim (Index 16):
The compound of any one of  claims 1 - 12 , wherein B is R i R j N\u2014; wherein R i  and R j  taken together with the nitrogen to which they are attached form a 4-9 membered monocyclic, bridged bicyclic, fused bicyclic or spirocyclic heterocyclic ring, which may have an additional heteroatom selected from the group consisting of N, O, and S(O) w  (wherein w is 0, 1 or 2); wherein the 4-9 membered monocyclic, bridged bicyclic, fused bicyclic or spirocyclic heterocyclic ring may be optionally substituted on carbon by one, two, or more substituents selected from the group consisting of halogen, hydroxyl, oxo, cyano, C 1-6 alkyl, C 1-6 alkoxy, and R a R b N-carbonyl-; wherein said C 1-6 alkyl may optionally be substituted by one, two, or more substituents selected from the group consisting of fluorine and hydroxyl; and wherein if said 4-9 membered monocyclic, bridged bicyclic, fused bicyclic or spirocyclic heterocyclic ring contains a \u2014NH moiety that nitrogen may be optionally substituted by a substituent selected from the group consisting of C 1-6 alkyl and C 1-6 alkyl-S(O) 2 \u2014; wherein C 1-6 alkyl and C 1-6 alkyl-S(O) 2 \u2014 may optionally be substituted by one or more fluorines.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 88.0
- Lexical Diversity: 1.40625
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15827074', '15354834', '15796519', '14974033', '14851909']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.846716378045462
- 35 USC 102 Novelty (BERT): 0.590678139817409
- Combined Prediction Score: 0.8211125542226566
- Mean Citation Score: 464.616548
- Max Citation Score: 551.8046
- Similarity Product: 479.6516094507098

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test