PATENT CLAIM ANALYSIS

Application Number: 16168548
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["546", "016000"]

Abstract:
Described herein is a compound having a chemical structure of Formula A: wherein m, p, q, W, Z, Y, X 1 , X 2 , R 1 , R 2 , R 3  and R 4  are as defined herein. A diastereo-selective reduction of the compound comprising contacting the compound of Formula A with a reducing agent in an aprotic polar or non-polar solvent is also described.

Claim (Index 1):
An isolated compound of Formula A: wherein: m is 1 or 2; p is 0, 1, or 2; q is 0, 1, or 2; W is C or N; Z is CH 2 , N, O, or S; Y is NH, O, S, or CH 2 ; X 1  and X 2  are hydrocarbons which together contain a total of five to nine carbon atoms and which link together such that the moiety: \u2003forms a bridged bicyclic ring system; R 1  and R 2  are independently H, halo, CN, OH, C 2-6  alkenyl, C 2-6  alkynyl, C 1-6  alkyl, C 1-6  haloalkyl, C 1-3  alkoxy, NR 5 R 6 , C 3-6  cycloalkyl, C 3-6  cycloalkenyl, NR 5 R 6 , COOR 5 , CONR 5 R 6 , NR 7 CONR 5 R 6 , NR 7 COOR 5 , OCONR 5 R 6 , SR 5 , SOR 5 , SO 2 R 5 , or C 1-6  alkylene-E; R 3  is H, OH, C 1-6  alkyl, C 1-6  haloalkyl, C 2-6  alkenyl, C 2-6  alkynyl, 3 to 6 membered cycloalkyl, heterocycloalkyl, aryl or heteroaryl, or C 1-6  alkylene-E; or R 1  and R 2 , or R 3  and R 2  together from a cycloalkyl or heterocycloalkyl each of which is optionally substituted with at least one group selected from OH, halo, CN, OH, C 1-6  alkyl, C 1-6  haloalkyl, C 1-3  alkoxy, and NH 2 ; E is OH, C 1-3  alkoxy, NR 5 R 6 , SR 5 , 3 to 6 membered cycloalkyl, heterocycloalkyl, aryl or heteroaryl; R 4  is H, C 1-5  alkyl, C 2-5  alkenyl, C 2-5  alkynyl, C 3-6  cycloalkyl, or C 3-6  cycloalkenyl, each of the alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl is optionally substituted with at least one group selected from OH, halo, CN, C 1-3  alkoxy, and NH 2 ; R 5 , R 6 , and R 7  are independently H or C 1-6  alkyl; provided that when Z is O, R 3  is H.

Metadata:
- Claim Count in Document: 137.0
- Percentile: 97.0
- Lexical Diversity: 1.58333
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['10500476', '13122679', '13857001', '13655176', '14620700']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7729032421049479
- 35 USC 102 Novelty (BERT): 0.5103745545628384
- Combined Prediction Score: 0.7466503733507369
- Mean Citation Score: 269.76020600000004
- Max Citation Score: 271.79846000000003
- Similarity Product: 198.7378458239091

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test