PATENT CLAIM ANALYSIS

Application Number: 16003232
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-09
Patent Classification: ["548", "301100"]

Abstract:
The present invention encompasses compounds of formula (I) wherein the groups R 1  to R 4 , R 7 , A, D, E, F, V, W, X, Y, n, r and q are defined in claim  1,  their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.

Claim (Index 4):
The compound according to  claim 1 , wherein\n R 1  is a group, optionally substituted by one or more, identical or different R b1  and/or R c1 , selected from among C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, C 6-10 aryl, 5-10 membered heteroaryl and 3-10 membered heterocyclyl;\n each R b1  is independently selected from among \u2014OR c1 , \u2014NR c1 R c1 , halogen, \u2014CN, \u2014C(O)R c1 , \u2014C(O)OR c1 , \u2014C(O)NR c1 R c1 , \u2014S(O) 2 R c1 , \u2014S(O) 2 NR c1 R c1 , \n \u2014NHC(O)R c1  and \u2014N(C 1-4 alkyl)C(O)R c1 ; \n each R c1  independently of one another denotes hydrogen or a group, optionally substituted by one or more, identical or different R d1  and/or R e1 , selected from among C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, C 6-10 aryl, 5-10 membered heteroaryl and 3-10 membered heterocyclyl; \n each R d1  is independently selected from among \u2014OR e1 , \u2014NR e1 R e1 , halogen, \u2014CN, \u2014C(O)R e1 , \u2014C(O)OR e1 , \u2014C(O)NR e1 R e1 , \u2014S(O) 2 R e1 , \u2014S(O) 2 NR e1 R e1 , \n \u2014NHC(O)R e1  and \u2014N(C 1-4 alkyl)C(O)R e1 ; \n each R e1  independently of one another denotes hydrogen or a group, optionally substituted by one or more, identical or different R f1  and/or R g1 , selected from among C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, C 6-10 aryl, 5-10 membered heteroaryl and 3-10 membered heterocyclyl; \n each R f1  is independently selected from among \u2014OR g1 , \u2014NR g1 R g1 , halogen, \u2014CN, \u2014C(O)R g1 , \u2014C(O)OR g1 , \u2014C(O)NR g1 R g1 , \u2014S(O) 2 R g1 , \u2014S(O) 2 NR g1 R g1 , \n \u2014NHC(O)R g1  and \u2014N(C 1-4 alkyl)C(O)R g1 ; \n each R g1  is independently selected from among hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 haloalkyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl, C 6-10 aryl, 5-10 membered heteroaryl and 3-10 membered heterocyclyl; \n or a salt thereof.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.45763
- Patent Class: 548.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15503754', '15287958', '14790032', '14683173', '13746411']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7939124946855732
- 35 USC 102 Novelty (BERT): 0.5702765360098182
- Combined Prediction Score: 0.7715488988179977
- Mean Citation Score: 386.50986600000016
- Max Citation Score: 452.09863
- Similarity Product: 435.40663159124017

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test