PATENT CLAIM ANALYSIS

Application Number: 15876810
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "253040"]

Abstract:
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R 1 -R 4  are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X 3  or P2X 2/3  receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.

Claim (Index 17):
A pharmaceutical composition useful for treating a respiratory dysfunction in a patient comprising an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt or prodrug thereof,\n wherein: \n R 1  is optionally substituted heteroaryl or NR 5 R 6 ; \n R 2  is optionally substituted aryl, optionally substituted heteroaryl, C 1  to C 6  alkyl, or S\u2014C 1  to C 6  alkyl; \n R 3  is H or C 1  to C 6  alkyl; \n R 4  is optionally substituted heteroaryl; \n R 5  and R 6  are, independently, selected from the group consisting of H, optionally substituted C 1  to C 6  alkyl, C 3  to C 6  cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, and CO(C 1  to C 6  alkyl); or \n R 5  and R 6  are joined to form a 5 or 6-membered heterocyclic ring optionally substituted by one or more of halogen, C 1  to C 6  alkyl, C 1  to C 6  alkoxy, C 1  to C 6  hydroxyalkyl, C 3  to C 6  cycloalkyl, C 1  to C 6  alkyl containing 1 to 3 fluorine atoms, C 3  to C 6  cycloalkyl-C 1  to C 6  alkyl, or CONH 2 , \n and a pharmaceutically acceptable carrier.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 86.0
- Lexical Diversity: 2.10909
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15184800', '15105526', '12337683', '12142846', '12868815']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8023487197810215
- 35 USC 102 Novelty (BERT): 0.6572823384234999
- Combined Prediction Score: 0.7878420816452694
- Mean Citation Score: 464.4129620000001
- Max Citation Score: 650.9054
- Similarity Product: 620.2185366262436

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test