PATENT CLAIM ANALYSIS

Application Number: 16095374
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["514", "480000"]

Abstract:
An object of the present invention is to provide a novel compound having a strong opening action with respect to KCNQ2-5 channels. A compound represented by the general formula (1) (wherein the definition of each group is as described in the specification) is provided. The compound represented by the general formula (1) has a strong opening action with respect to KCNQ2-5 channels, and therefore is useful as a prophylactic and/or therapeutic agent for a KCNQ2-5 channel-related disease (for example, dysuria, overactive bladder, or the like).

Claim (Index 6):
The compound or a pharmaceutically acceptable salt thereof according to  claim 1 , wherein the compound is (1) 1-(4,6-dichloro-1-hydroxy-1-methyl-2,3-dihydro-1H-inden-5-yl)-3-{[5-(trifluoromethyl)-2-pyridinyl]methyl}urea, (2) 1-[4,6-dichloro-1-hydroxy-1-(trifluoromethyl)-2,3-dihydro-1H-inden-5-yl]-3-(4-fluorobenzyl)urea, (3) 1-[4,6-dichloro-1-hydroxy-1-(trifluoromethyl)-2,3-dihydro-1H-inden-5-yl]-3-{[5-(trifluoromethyl)-2-pyridinyl]methyl}urea, (4) 1-[4,6-dichloro-1-hydroxy-1-(trifluoromethyl)-2,3-dihydro-1H-inden-5-yl]-3-[(1R)-1-(4-fluorophenyl)ethyl]urea, or (5) 1-(4,6-dichloro-2,2-difluoro-1-hydroxy-1-methyl-2,3-dihydro-1H-inden-5-yl)-3-(4-fluorobenzyl)urea.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 97.0
- Lexical Diversity: 1.75439
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['16059270', '10506746', '10583469', '12893592', '11500207']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7892045252343635
- 35 USC 102 Novelty (BERT): 0.541873470272169
- Combined Prediction Score: 0.764471419738144
- Mean Citation Score: 344.198492
- Max Citation Score: 371.80588
- Similarity Product: 293.1993458400464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test