PATENT CLAIM ANALYSIS

Application Number: 15767246
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-03
Patent Classification: ["435", "069100"]

Abstract:
The present invention relates in general to a method of producing a recombinant protein, in particular hG-CSF, with reduced impurities resulting from truncation of said recombinant protein. The present invention also relates to a composition comprising a protein obtained with the inventive method.

Claim (Index 2):
The method according to  claim 1 , wherein the nitrogen source level is increased to a concentration above standard by:\n i) increasing the levels of the nitrogen source in the medium prior to cultivating the host cells in said medium, ii) increasing NH 4 OH during medium preparation and prior to sterilization; iii) adding additional nitrogen source to a complex nutrient source and using said complex nutrient source when preparing the medium; and/or iv) adding additional nitrogen source to the medium while already culturing the host cells.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 91.0
- Lexical Diversity: 1.56667
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10632695', '13076315', '11722527', '10651395', '13122487']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6137698011488036
- 35 USC 102 Novelty (BERT): 0.5063225958417917
- Combined Prediction Score: 0.6030250806181024
- Mean Citation Score: 211.031536
- Max Citation Score: 216.50233
- Similarity Product: 125.3446794630647

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test