PATENT CLAIM ANALYSIS

Application Number: 16028112
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "101000"]

Abstract:
The present invention includes composition and methods for inhibiting or decreasing impaired systolic ejection fraction associated with cardiotoxic therapeutic treatment in a subject receiving a cardiotoxic chemotherapeutic agent causing impaired systolic ejection fraction comprising: identifying a subject in need of cardioprotection from the therapeutic treatment; and delivering an effective amount of a phospholipid or derivatives thereof that is cardioprotective to the heart of the subject thereby inhibiting or decreasing impaired systolic ejection fraction associated with administration of the cardiotoxic chemotherapeutic treatment to the subject.

Claim (Index 26):
A method of evaluating a candidate drug believed to be useful in treating cardiotoxicity caused by a therapeutic agent, the method comprising:\n (a) measuring the cardiotoxicity from a set of patients; (b) administering a candidate drug to a first subset of the patients, and a placebo to a second subset of the patients; (c) repeating step (a) after the administration of the candidate drug or the placebo; and (d) determining if the candidate drug reduces the cardiotoxicity caused by the therapeutic agent that is statistically significant as compared to any reduction occurring in the second subset of patients, wherein a statistically significant reduction indicates that the candidate drug is useful in treating said disease state.

Metadata:
- Claim Count in Document: 31.0
- Percentile: 95.0
- Lexical Diversity: 1.70588
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15297901', '15347381', '15788683', '14729940', '14844475']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7476517116342736
- 35 USC 102 Novelty (BERT): 0.5140015424376303
- Combined Prediction Score: 0.7242866947146093
- Mean Citation Score: 261.440028
- Max Citation Score: 279.11548
- Similarity Product: 179.37121975354907

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test