PATENT CLAIM ANALYSIS

Application Number: 15960642
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-12
Patent Classification: ["800", "018000"]

Abstract:
Genetically modified non-human animals comprising a human or humanized interleukin-7 (IL-7) gene. Cells, embryos, and non-human animals comprising a human or humanized IL-7 gene. Rodents that express human or humanized IL-7 protein. Genetically modified mice that comprise a human or humanized IL-7-encoding gene in their germline, wherein the human or humanized IL-7-encoding gene is under control of endogenous mouse IL-7 regulatory sequences.

Claim (Index 21):
A genetically modified mouse whose genome comprises a replacement of a genomic fragment of a mouse IL-7 gene at an endogenous mouse IL-7 locus with a genomic fragment comprising exons 2, 3, 4, 5 and 6 of a human IL-7 gene to form a humanized IL-7 gene at the endogenous mouse IL-7 locus, wherein the human IL-7 gene comprises the nucleotide sequence of SEQ ID NO: 3;\n the resulting modified mouse IL-7 locus lacks mouse IL-7 exons 2, 3, 4 and 5; the humanized IL-7 gene is under control of endogenous mouse IL-7 5\u2032 regulatory elements; and the IL-7 protein encoded by the humanized IL-7 gene is expressed in the serum of the genetically modified mouse.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 1.82051
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14551538', '15649797', '15357021', '13795765', '15832976']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6133002483139927
- 35 USC 102 Novelty (BERT): 0.5553407170300007
- Combined Prediction Score: 0.6075042951855935
- Mean Citation Score: 421.546982
- Max Citation Score: 435.40295
- Similarity Product: 389.6716957008512

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test