PATENT CLAIM ANALYSIS

Application Number: 16018247
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["435", "072000"]

Abstract:
The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.

Claim (Index 18):
The engineered transaminase polypeptide of  claim 17 , wherein the transaminase polypeptide sequence comprises at least one additional substitution selected from: X30 is A; X31 is A; X57 is I; X82 is H; X85 is V; X85 is C; X153 is S; X177 is L; X317 is M; X317 is Y; X417 is A; X319 is Q; X320 is A; X417 is I; X113 is H and X407 is S; X44 is A and X166 is S; X314 is V and X409 is G; X153 is S and X233 is S; X311 is V and X314 is T; X153 is S, X318 is R and X417 is E; X153 is C, X233 is L and X318 is R; X153 is S, X317 is L and X417 is C; X233 is L, X321 is L, and X417 is I; and X153 is C, X317 is Y and X319 is Q.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 94.0
- Lexical Diversity: 1.47368
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14684916', '15912892', '15341631', '13920902', '13381155']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.779543174295908
- 35 USC 102 Novelty (BERT): 0.7641677647882514
- Combined Prediction Score: 0.7780056333451424
- Mean Citation Score: 789.1678159999999
- Max Citation Score: 898.8333
- Similarity Product: 887.2542667267978

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test