PATENT CLAIM ANALYSIS

Application Number: 16085163
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["560", "118000"]

Abstract:
A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.

Claim (Index 3):
A process according to  claim 2 , further comprising the step of reacting the obtained compound of formula I with a nucleophile, such as HOR 1 , HSR 1 , HNR 1 R 2 , \u2014N 3 , H 3 N, H 2 N\u2014NHR 1 , H 2 N\u2014OR 1 , R 4 \u2014CH(\u2550N 2 ), N-hydroxy-2-thiopyridone or a coupling partner, a coupling partner being an alkali metal organyl or an alkaline earth metal organyl (MR 1 , wherein M is Li, Na or Mg), a stannane (R 1 Sn(R 2 ) 3 ), a cuprate ([R 1 CuR 1 ] \u2212  or [R 1 CuCN \u2212 ]) an organozinc compound (R 1 ZnQ, or R 1 ZnR 1 , wherein Q is halogen), an organobismuth compound ((R 1 ) 3 Bi), a boronic acid R 1 B(OH) 2 , a boronic ester R 1 B(OR 2 ) 2  or a potassium trifluoroborate R 1 BF 3 K, wherein R 1  and R 2  are independently of each other H, saturated linear or branched \u2014(C 1 -C 20 )alkyl, aryl or form together a cycle and R 4  represents H, saturated or unsaturated linear or branched \u2014(C 1 -C 20 )alkyl, TMS, aryl or form together a cycle to obtain a compound of formula V wherein Z is C, S or S(\u2550O); Y is R 1 \u2014C(\u2550O)\u2014, R 1 OC(\u2550O)\u2014, CH 2 F\u2014, CHF 2 \u2014, CF 3 \u2014, C 2 F 5 \u2014, C 3 F 7 \u2014, \u2014CN, R 1 R 2 NC(\u2550O)\u2014, R 1 SC(\u2550O)\u2014, R 1 R 2 N\u2014, \u2014NO 2 , \u2014CH(\u2550NOR 1 ), wherein R 1  and R 2  are independently of each other H, saturated linear or branched \u2014(C 1 -C 20 )alkyl, aryl or form together a cycle; G is \u2014OR 1 , \u2014SR 1 , \u2014NR 1 R 2 , \u2014N 3 , \u2014NH 2 \u2014NH\u2014NHR 1 , \u2014NH\u2014OR 1 , \u2014C(\u2550N 2 ) R 4 , \u2014O\u2014(N-2-thiopyridone), R 1 , \u2014OC(\u2550O)R 1 , wherein R 1  and R 2  are independently of each other H, saturated linear or branched \u2014(C 1 -C 20 )alkyl, aryl, heteroaryl or form together a cycle and R 4  represents H, saturated or unsaturated linear or branched \u2014(C 1 -C 20 )alkyl, TMS, aryl or form together a cycle.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 97.0
- Lexical Diversity: 1.47368
- Patent Class: 560.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10203031', '11609580', '15123898', '15514294', '13216927']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6641580176534723
- 35 USC 102 Novelty (BERT): 0.529349601466883
- Combined Prediction Score: 0.6506771760348133
- Mean Citation Score: 230.822316
- Max Citation Score: 234.68832
- Similarity Product: 170.37584736053464

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test