PATENT CLAIM ANALYSIS

Application Number: 16143748
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-05
Patent Classification: ["424", "001890"]

Abstract:
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.

Claim (Index 35):
The contrast agent of  claim 26 , having the structure of formula (IV): wherein:\n J is selected from N(R 27 ), S, O, C(\u2550O), C(\u2550O)O, NHCH 2 CH 2 O, a bond, and C(\u2550O)N(R 27 ), with each group being drawn with its left end attached to G and its right end attached to the carbon substituted with R 21  and R 22 ; \n when present, K is selected from hydrogen, alkoxyalkyl, alkyloxy, aryl, C 1 -C 6  alkyl optionally substituted with an imaging moiety, heteroaryl, and an imaging moiety; \n L is selected from hydrogen, alkoxyalkyl, alkyloxy, aryl, C 1 -C 6  alkyl optionally substituted with an imaging moiety, heteroaryl, and an imaging moiety; \n M is selected from hydrogen, alkoxyalkyl, alkyloxy, aryl, C 1 -C 6  alkyl optionally substituted with an imaging moiety, heteroaryl, and an imaging moiety; or \n L and M, together with the atom to which they are attached, form a three- or four-membered carbocyclic ring; \n Q is halo or haloalkyl; \n n is 0, 1, 2, or 3; \n R 21 , R 22 , R 23 , R 24 , R 25 , R 26 , R 27 , R 28 , R 35 , R 36 , R 37 , R 38 , and R 39  are independently selected from hydrogen, C 1 -C 6  alkyl optionally substituted with an imaging moiety, and an imaging moiety; and \n Y is selected from a bond, carbon, and oxygen, provided that when Y is a bond, K and L are absent and M is selected from aryl and heteroaryl; and provided that when Y is oxygen, K and L are absent and M is selected from hydrogen, alkoxyalkyl, aryl, C 1 -C 6  alkyl optionally substituted with an imaging moiety, and heteroaryl; \n provided that at least one imaging moiety is present in formula (IV).

Metadata:
- Claim Count in Document: 11.0
- Percentile: 97.0
- Lexical Diversity: 1.34286
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['13529756', '15153502', '14845320', '12014161', '15629068']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8097739619503564
- 35 USC 102 Novelty (BERT): 0.5809968194497256
- Combined Prediction Score: 0.7868962477002934
- Mean Citation Score: 365.333556
- Max Citation Score: 434.32803
- Similarity Product: 342.14193400571287

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test