PATENT CLAIM ANALYSIS

Application Number: 15896433
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-12
Patent Classification: ["435", "462000"]

Abstract:
Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered non-naturally occurring nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Targetable nuclease systems can be used to edit genetic targets, including recursive genetic engineering and trackable genetic engineering methods.

Claim (Index 1):
A nucleic acid-guided nuclease system comprising:\n (a) a nucleic acid-guided nuclease comprising the amino acid sequence of SEQ ID NO: 2; (b) a heterologous engineered guide nucleic acid for of complexing with the nucleic acid-guided nuclease, wherein said heterologous engineered guide comprises a pseudoknot region nucleotide residues 18-28 and 31-32 of SEQ ID No. 197, and (c) an editing sequence having a change in sequence relative to the sequence of a target region; wherein the system results in an edit in the target region facilitated by the nuclease, the heterologous engineered guide nucleic acid, and the editing sequence.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 88.0
- Lexical Diversity: 2.0625
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15896444', '15631989', '15632001', '15632222', '14213723']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6318399999662632
- 35 USC 102 Novelty (BERT): 0.6383376811775269
- Combined Prediction Score: 0.6324897680873895
- Mean Citation Score: 501.3898520000001
- Max Citation Score: 625.8911
- Similarity Product: 579.4435796822607

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test