PATENT CLAIM ANALYSIS

Application Number: 16092680
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["530", "324000"]

Abstract:
The present invention is in the field of medicine and provides means and methods for the treatment, prevention or amelioration of osteoarthritis. More in particular, it provides a peptide for use in the treatment, amelioration or prevention of osteoarthritis, wherein the peptide consists of an amino acid sequence according to SEQ ID NO: 18 or an analogue thereof, wherein the analogue is a peptide consisting of an amino acid sequence according to formula 1 (SEQ ID NO: 29), or a fragment thereof wherein the fragment consists of at least 10 consecutive amino acids of SEQ ID NO: 18 or an amino acid sequence according to formula 1.

Claim (Index 1):
A method for the treatment or amelioration of osteoarthritis, the method comprising:\n administering to a subject in need thereof a therapeutically effective amount of a peptide; wherein the peptide consists of an amino acid sequence according to SEQ ID NO: 18 or an analogue thereof, wherein the analogue is a peptide consisting of an amino acid sequence according to formula 1 (SEQ ID NO: 29), or a fragment thereof, wherein the fragment consists of at least 10 consecutive amino acids of SEQ ID NO: 18 or an amino acid sequence according to formula 1, wherein formula 1 is: (SEQ\u2003ID\u2003NO:\u200329) P\u2003K\u2003P\u2003S\u2003S\u2003X1\u2003P\u2003X2\u2003X3\u2003L\u2003X4\u2003X5\u2003I\u2003X6\u2003V\u2003X7\u2003X8\u2003X9\u2003D\u2003X10   X11\u2003X12\u2003X13\u2003X14\u2003X15\u2003X16\u2003X17\u2003X18\u2003X19\u2003X20\u2003X21\u2003M\u2003V\u2003V   X22\u2003X23\u2003S\u2003G\u2003S\u2003X24, and\n wherein; \n X1=A or V \n X2=T or D or E \n X3=Q or D or K or S \n X4=N or D or E or H \n X5=A or D or S \n X6=S or I or L or M or F or Y or E or H or K or Q or R or D \n X7=L or E or K or T or M or R \n X8=Y or A or D or E or H or K or S or T \n X9=F or H or A or D or E or K or Q or R or Y \n X10=D or I or L or E or N or S or T \n X11=S or D or E or N or R \n X12=S or D or E or K or N or T \n X13=N or E or Q or R \n X14=V or A or D or N or R or T or M or Y or H \n X15=I or A or D or E or K or N or Q or R or S or T or V \n X16=L or A or E or K or Q \n X17=K or D or E or G or Q or R or W \n X18=K or A or D or E or H or N or P or Q or S or T or I or V or M \n X19=Y or D or E or H or K or Q or I or R \n X20=R or D or E or K or N or S \n X21=N or D \n X22=R or E or S or D or K or Q or L \n X23=A or E or D or S \n X24=H or R.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 2.22222
- Patent Class: 530.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16092671', '12932876', '12012521', '12774293', '12211385']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6908847618771095
- 35 USC 102 Novelty (BERT): 0.5868830114386793
- Combined Prediction Score: 0.6804845868332664
- Mean Citation Score: 350.589832
- Max Citation Score: 615.9391
- Similarity Product: 398.7110396577359

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test