PATENT CLAIM ANALYSIS

Application Number: 15759119
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["564", "057000"]

Abstract:
Provided are a cyclohexane derivative as shown by formula IB or a stereoisomer or a salt thereof, and the preparation and use thereof. The cyclohexane derivative has a high affinity for D 3  receptors and 5-hydroxytryptamine, has a lower affinity for D 2  receptors, shows a high selectivity for D 3 /D 2  receptors, and can be used as a therapeutic drug against neuropsychiatric diseases; and the preparation method thereof is simple and easy.

Claim (Index 5):
The cyclohexane derivative or stereoisomer or salt thereof according to  claim 1 , wherein the cyclohexane derivative or stereoisomer or salt thereof is selected from the following compounds or salts thereof:\n N\u2032-[trans-4-[2-[4-(benzo[b]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 1; N\u2032-[trans-4-[2-[7-(benzo[b]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 2; N\u2032-[trans-4-[2-[4-(benzo[c]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 3; N\u2032-[trans-4-[2-[4-(6-fluoro-benzo[d]isoxazol)-3-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 5; N\u2032-[trans-4-[2-[4-(3-chloro-benzo[d]isoxazol)-6-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 6; N\u2032-[trans-4-[2-[4-(6-fluoro-benzo[d]isoxazol)-3-piperidyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 7; N\u2032-[trans-4-[2-[4-(benzo[b]thiophene)-7-piperidinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 8; N\u2032-[trans-4-[2-[7-(benzo[b]thiophene)-7-piperidinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 9; N\u2032-[trans-4-[2-[4-(benzo[c]thiophene)-7-piperidinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 10; N\u2032-[trans-4-[2-[4-(benzo[d]isothiazolyl)-3-piperidinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 11; N\u2032-[trans-4-[2-[4-(3-chloro-benzo[d]isoxazol)-6-piperidinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 12; N\u2032-[trans-4-[2-[4-(3-methyl-benzo[d]isoxazol)-6-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 13; N\u2032-[trans-4-[2-[4-(6-methyl-benzo[d]isoxazol)-4-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, compound 14.

Metadata:
- Claim Count in Document: 39.0
- Percentile: 90.0
- Lexical Diversity: 1.7234
- Patent Class: 564.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14889831', '15124264', '15029218', '13123368', '13056365']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6995847922655839
- 35 USC 102 Novelty (BERT): 0.5253527480951784
- Combined Prediction Score: 0.6821615878485433
- Mean Citation Score: 248.190766
- Max Citation Score: 269.30753
- Similarity Product: 223.34093657497823

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test