PATENT CLAIM ANALYSIS

Application Number: 15951838
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "649000"]

Abstract:
A hitherto unknown crystalline form of (−)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride, pharmaceutical compositions containing the new crystalline form, methods of producing the new crystalline form, and a related method of use including treatment of, e.g., pain and/or urinary incontinence.

Claim (Index 14):
A pharmaceutical composition comprising, as an active ingredient, a crystalline Form A of (\u2212)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride produced by the process of\n dissolving (\u2212)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride of Form B in acetonitrile together with active carbon, heating the solution to the boiling point, removing the active carbon by filtering, stirring the solution at a temperature below 40\u00b0 C., removing insoluble residue by filtering and removing part of the solvent, leaving (\u2212)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride of Form A to crystallize, redissolving the resulting crystals in acetonitrile, removing insoluble residue by filtering and removing part of the solvent, and leaving (\u2212)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride of Form A to crystallize, and at least one suitable additive or auxiliary substance.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 91.0
- Lexical Diversity: 1.47222
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12634777', '12329111', '15033331', '12016506', '12850208']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7452463741538454
- 35 USC 102 Novelty (BERT): 0.5729909470129954
- Combined Prediction Score: 0.7280208314397605
- Mean Citation Score: 274.238098
- Max Citation Score: 452.5927
- Similarity Product: 422.4388197006344

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test