PATENT CLAIM ANALYSIS

Application Number: 15946634
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "256000"]

Abstract:
Inhibitors of SecA, and methods of making and using thereof, are described herein. The compounds described herein can be used to treat or prevent microbial infections, such as bacterial infections.

Claim (Index 39):
The pharmaceutical composition of  claim 17 , further comprising one or more further compounds, or a pharmaceutically acceptable salt thereof, wherein the further compounds have, independently, the following formula: wherein\n X and Y of Formula III are independently N or C; \n D and G of Formula III are independently NR 7 , CR 8 R 9 , O, or S; \n A, B, E, and F of Formula III are independently N or CR 10 ; \n L and M of Formula III are independently S, SO, SO 2 , O, NR 11 , or CR 12 R 13  \n J of Formula III is O, S, SO, SO 2 , NR 14 , or CR 15 R 16 ; and \n R 1 -R 16  of Formula III are independently absent or selected from hydrogen, substituted or unsubstituted, linear, branched, hetero, or cyclic alkyl, alkenyl, or alkynyl; halogen; substituted or unsubstituted alkoxy; hydroxy, cyano, formyl, acyl, carboxylic acid, carboxylate, \u2014CONH 2 , \u2014CONHR 17 , \u2014CONR 17 R 17 , \u2014OCONHR 17 , \u2014NHCOOR 17 , \u2014OCONR 17 R 17 , \u2014NR 14 COOR 17 , NHCONHR 17 ; \u2014NR 14 CONHR 17 , \u2014NHCONR 17 R 17 , \u2014NR 17 CONR 17 R 17 , \u2014CH 2 OH, \u2014CHR 17 OH, \u2014CR 17 R 17 OH, \u2014COOR 17 , thiol, \u2014NH 2 , \u2014NHR 17 , \u2014NR 17 R 17 , \u2014SR 17 , \u2014SOR 17 , and \u2014SOOR 17 , wherein R 17  of Formula III is defined the same as R 1 -R 16  of Formula III; or \n wherein\n Z and W of Formula X or Xa are O, S, SO, SO 2 , NR 5 , or CR 6 R 7 ; \n X and Y of Formula X or Xa are independently N, NR 8 , or CR 9 R 10 ; \n Cy of Formula X or Xa is substituted or unsubstituted aryl, heteroaryl, cycloalkyl, or heterocycloalkyl group; and \n R 1 -R 10  of Formula X or Xa are independently absent or selected from hydrogen, substituted or unsubstituted, linear, branched, hetero, or cyclic alkyl, alkenyl, or alkynyl; substituted or unsubstituted aryl or heteroaryl; halogen; substituted or unsubstituted alkoxy; hydroxy, cyano, formyl, acyl, carboxylic acid, carboxylate, \u2014CONH 2 , \u2014CONHR 11 , \u2014CONR 11 R 11 , \u2014OCONHR 11 , \u2014NHCOOR 11 , \u2014OCONR 11 R 11 , \u2014NR 14 COOR 11 , NHCONHR 11 , \u2014NR 11 CONHR 11 , \u2014NHCONR 11 R 11 , \u2014NR 14 CONR 11 R 11 , \u2014CH 2 OH, \u2014CHR 11 OH, \u2014CR 11 R 11 OH, \u2014COOR 11 , thiol, \u2014NH 2 , \u2014NHR 11 , \u2014NR 11 R 11 , \u2014SR 11 , \u2014SOR 11 , and \u2014SOOR 11 , wherein R 11  of Formula X or Xa is defined the same as R 1 -R 10  of Formula X or Xa.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 91.0
- Lexical Diversity: 1.2963
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14406085', '10536899', '15222734', '15135334', '15620761']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7440486156601243
- 35 USC 102 Novelty (BERT): 0.5464250117412205
- Combined Prediction Score: 0.7242862552682339
- Mean Citation Score: 247.46465
- Max Citation Score: 416.0576
- Similarity Product: 279.79693162727347

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test