PATENT CLAIM ANALYSIS

Application Number: 16297133
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-06
Patent Classification: ["424", "193100"]

Abstract:
A polyplex of a double stranded RNA (dsRNA) and a polymeric conjugate consists of a linear polyethyleneimine (PEI) covalently linked to one or more polyethylene glycol (PEG) moieties. Each PEG moiety is conjugated via a linker to a targeting moiety capable of binding to a cancer antigen. Exemplary cancer antigens include epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2) and prostate surface membrane antigen (PSMA).

Claim (Index 19):
A polyplex of a double stranded RNA (dsRNA) and a polymeric conjugate, wherein said polymeric conjugate consists of a linear polyethyleneimine (LPEI) covalently linked to one polyethylene glycol (PEG) moiety, said PEG moiety being conjugated via a linker to a targeting moiety capable of binding to a cancer antigen, wherein the polymeric conjugate is a diconjugate of the formula (ii) linked to said targeting moiety and wherein said targeting moiety is hEGF, wherein the hEGF is linked via an amino group to said linker, and wherein said dsRNA is polyinosinic-polycytidylic acid double stranded RNA (poly I:C), and wherein m is 200-700 and n is 20-200.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 99.0
- Lexical Diversity: 1.54545
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15310735', '13237168', '13122667', '14351789', '12134556']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7213827576547597
- 35 USC 102 Novelty (BERT): 0.742510684660713
- Combined Prediction Score: 0.7234955503553551
- Mean Citation Score: 339.636158
- Max Citation Score: 830.25586
- Similarity Product: 821.8648758602154

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test