PATENT CLAIM ANALYSIS

Application Number: 16072382
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["800", "008000"]

Abstract:
The invention provides methods of treating schizophrenia in a subject, including for example, administering to the subject an agent that inhibits expression or activity of a C4A polynucleotide or polypeptide. The invention also provides methods of identifying a subject having or at risk of developing schizophrenia involving measuring or detecting an alteration in the level, copy number, and/or sequence of complement component C4A or complement component C4B relative to a reference.

Claim (Index 16):
A method of characterizing a subject having a mental disorder, the method comprising measuring\n a level of a complement component 4A (C4A) polynucleotide or polypeptide, a combined level of C4A and complement component 4B (C4B) polynucleotide or polypeptide, a copy number of C4A polynucleotide, and/or a sequence of C4A and/or C4B polynucleotide relative to a reference in a biological sample obtained from the subject, wherein an increase in the level of C4A polynucleotide or polypeptide, an increase in the combined level of C4A and C4B polynucleotide or polypeptide, an increase in C4A copy number and/or an alteration in a sequence of C4A or C4B polynucleotide indicates the subject has schizophrenia or is at risk of developing schizophrenia.

Metadata:
- Claim Count in Document: 31.0
- Percentile: 95.0
- Lexical Diversity: 1.60417
- Patent Class: 800.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15029224', '14388791', '10107604', '10222945', '10150821']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5843529214253987
- 35 USC 102 Novelty (BERT): 0.4872519228576673
- Combined Prediction Score: 0.5746428215686257
- Mean Citation Score: 207.578086
- Max Citation Score: 218.4893
- Similarity Product: 144.81310927681926

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test