PATENT CLAIM ANALYSIS

Application Number: 15742512
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["424", "001890"]

Abstract:
The present invention relates to a method of in vivo imaging and in particular to a method for the evaluation of in vivo images of beta amyloid (Aβ) distribution in the brain of a subject suspected of having Alzheimer's disease (AD). The method of the present invention provides more detailed information to the clinician as compared with prior art methods, facilitating identification of those subjects who will benefit most from disease modifying therapies.

Claim (Index 1):
A method for staging beta amyloid (A\u03b2) pathology in a subject's brain wherein said method comprises:\n (i) obtaining an in vivo image of said subject's brain using a A\u03b2 imaging agent; (ii) determining from said in vivo image the uptake of said A\u03b2 imaging agent in a cortical region of said brain; and, (iii) determining from said in vivo image the uptake of said A\u03b2 imaging agent in a striatal region of said brain; wherein positive uptake of said A\u03b2 imaging agent in said cortical region and negative uptake of said A\u03b2 imaging agent in said striatal region indicates Thal Phase 3 A\u03b2 pathology and wherein positive uptake of said A\u03b2 imaging agent in said cortical region and positive uptake of said A\u03b2 imaging agent in said striatal region indicates Thal Phase 4 or 5 A\u03b2 pathology.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 86.0
- Lexical Diversity: 1.47273
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['12418177', '14893091', '10388173', '14869862', '12917113']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6969458883373741
- 35 USC 102 Novelty (BERT): 0.502217216408989
- Combined Prediction Score: 0.6774730211445357
- Mean Citation Score: 216.538076
- Max Citation Score: 240.28098
- Similarity Product: 182.09587878991485

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test