PATENT CLAIM ANALYSIS

Application Number: 16200334
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["424", "423000"]

Abstract:
Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject.

Claim (Index 16):
A population of hydrogel capsules encapsulating cells, wherein the capsules contain cells to be transplanted selected from the group consisting of mammalian secretory cells, mammalian metabolic cells, mammalian structural cells, and aggregates thereof , wherein all of the capsules in the population of capsules have a diameter of at least 1 mm and less than 8 mm, and wherein the hydrogel capsules elicit less of a fibrotic reaction after implantation than the same capsules having a diameter of less than 1 mm.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 98.0
- Lexical Diversity: 1.58333
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14776639', '13831250', '13400382', '15831570', '15317657']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8293404723915356
- 35 USC 102 Novelty (BERT): 0.6040688706264549
- Combined Prediction Score: 0.8068133122150276
- Mean Citation Score: 458.67156000000006
- Max Citation Score: 582.405
- Similarity Product: 471.0192647668719

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test