PATENT CLAIM ANALYSIS

Application Number: 16292110
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-06
Patent Classification: ["514", "412000"]

Abstract:
The disclosure provides compounds having formula (I), where the substituents are as defined herein. The compounds are useful for modulating the dopamine D3 receptor and for treating conditions associated therewith, such as addictions, drug dependency, and psychiatric conditions.

Claim (Index 1):
A compound, or a pharmaceutically acceptable salt thereof, having the formula: wherein; A is a saturated 4-6 carbocyclic ring, optionally in which one or two carbon atoms is heteroatoms selected among nitrogen and oxygen; and in which the group G is linked to a carbon or nitrogen; such ring may optionally be substituted at the carbon atoms or nitrogen atom by one or more C 1-4 alkyl groups; B is a saturated 4-6 heterocyclic ring in which one or two carbon atoms is heteroatoms selected among Nitrogen or Oxygen and the linking atom is always a Nitrogen atom; such ring may be also substituted at the carbon atoms or, possibly, at the different Nitrogen atom, by one or more C 1-4 alkyl group; G is phenyl, or a 5-6 membered heteroaromatic group, which is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, hydroxyl, amino, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkanoyl, haloC 1-4 alkoxy, SF 5 , \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)OR 3 ; W is S, SO 2 , O, CHR 2 , NR 3 ; n is 0 or 1; m is 1 or 2; p is 1 or 2; z is 0 or 1; R is hydrogen, C 1-4 alkyl; C 1-4 alkoxy; R 1  is hydrogen, F, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; R 2  is hydrogen, F, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; R 3  is hydrogen, C 1-4 alkyl; R 4  is hydrogen or C 1-4 alkyl; or \u2014C(\u2550O)C 1-4 alkyl; \u2014C(\u2550O)C 1-4 alkoxyC 1-4 alkyl; \u2014C(\u2550O)cyclopropyl; R 5  is hydrogen, C 1-4 alkyl; R 6  is hydrogen, C 1-4 alkyl; R 7  is halogen, C 1-4 alkyl; hydroxyl, C 1-4 alkoxy; G 1  is phenyl or a 5-6-membered heteroaromatic group or a 8-11 membered heteroaromatic group; any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, hydroxyl, amino, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, SF 5 , \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)(O) z R 3 ; Y is phenyl or a moiety selected from the group consisting of: 5-6 membered heteroaromatic group, a 8-11 membered heteroaromatic group; a saturated mono 3-7 membered carbocyclic group or a 8-11 membered bicyclic carbocyclic group in which one or more atom carbons may be replaced by N(R 4 ) z , O, S; any of such groups may be optionally substituted by 1, 2 or 3 substituents selected from: halogen, cyano, hydroxyl, C 1-4 alkylamino, C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, C 1-4 alkanoyl, \u2014C(\u2550O),\u2014NHR 4 , \u2014NR 5 R 6 , SF 5 , \u2014C(\u2550O) z R 3 , \u2014\u2550O, and (CH 2 ) z C(\u2550O)N(R 4 R 5 ); when G 1  is a phenyl group, then G 1  and Y may be fused together to form a benzofused aromatic or heteroaromatic system which might be optionally substituted by one or two substituents selected from: halogen, cyano, hydroxy, amino C 1-4 alkyl, haloC 1-4 alkyl, C 1-4 alkoxy, haloC 1-4 alkoxy, C 1-4 alkanoyl, \u2014C(\u2550O)NH 2 , \u2014C(\u2550O)OR 3 , and SF 5 .

Metadata:
- Claim Count in Document: 38.0
- Percentile: 99.0
- Lexical Diversity: 1.35294
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15750128', '11792596', '11911035', '11991576', '15583679']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7997211613054553
- 35 USC 102 Novelty (BERT): 0.5972034798118653
- Combined Prediction Score: 0.7794693931560963
- Mean Citation Score: 378.9739
- Max Citation Score: 536.0148
- Similarity Product: 434.7154093384266

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test