PATENT CLAIM ANALYSIS

Application Number: 16083879
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-03
Patent Classification: ["549", "023000"]

Abstract:
Disclosed are a retinoid compound, a preparation method therefor, intermediates thereof and an application thereof. The retinoid compound I of the present invention has a good tumor growth inhibition rate.

Claim (Index 1):
A compound represented by formula I, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, wherein, U is CR 9a  or N; V is CR 9b  or N; X is CR 9c  or N; W is CR 9d  or N; in the definition of U, V, X and W, each of R 9a , R 9b , R 9c  and R 9d  is independently hydrogen, hydroxy, nitro, cyano, halogen, C 1 -C 6  alkyl, C 1 -C 6  alkyl substituted with halogen, C 1 -C 6  alkoxy, \u2014NR 10 R 11 , or \u2014COOR 14 ;\n each of R 10 , R 11 , R 12 , R 13  and R 14  is independently hydrogen or C 1 -C 6  alkyl; \n the bond connecting AE, EG or GZ is independently a single bond or a double bond; when A, E, G or Z connects to two single bonds, the corresponding A, E, G and Z are independently \u2014(CR 2 R 3 )\u2014, \u2014C(\u2550O)\u2014, \u2014(NR 4 )\u2014, \u2014O\u2014, \u2014S\u2014, \u2014S(\u2550O)\u2014 or \u2014SO 2 \u2014; when A, E, G or Z connects to a single bond and a double bond, the corresponding A, E, G and Z are independently \u2014(CR 5 )\u2550 or \u2014N\u2550; \n each of R 2 , R 3 , R 4  and R 5  is independently hydrogen, hydroxy, halogen, C 1 -C 6  alkyl, C 2 -C 6  alkenyl, C 1 -C 6  alkyl substituted with halogen, C 1 -C 6  alkoxy, C 1 -C 6  acyl, C 6 -C 10  aryl or \u201cC 3 -C 6  heteroaryl having 1 to 2 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen\u201d; \n m is 0, 1, 2 or 3; \n when there are more than one substituents of R 1 , the substituents are identical or different; R 1  is hydrogen, hydroxy, nitro, cyano, halogen, C 1 -C 6  alkyl, C 1 -C 6  alkyl substituted with halogen, C 1 -C 6  alkoxy, \u2014NR 6 R 7  or \u2014COOR 8 ; \n each of R 6 , R 7  and R 8  is independently hydrogen or C 1 -C 6  alkyl; \n Y is \u2014CN, \u2014COOR 15  or \u2014CO 2 NHR 16 ; \n each of R 15  and R 16  is independently hydrogen, C 1 -C 6  alkyl, C 2 -C 6  alkenyl or C 1 -C 6  alkylacyl; \n the compound represented by formula I is not

Metadata:
- Claim Count in Document: 1.0
- Percentile: 97.0
- Lexical Diversity: 1.25926
- Patent Class: 549.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15025618', '12780132', '15999075', '13302409', '12524545']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8001539168300842
- 35 USC 102 Novelty (BERT): 0.5127331195273543
- Combined Prediction Score: 0.7714118370998112
- Mean Citation Score: 315.0832680000001
- Max Citation Score: 317.32526
- Similarity Product: 260.74774759946587

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test