PATENT CLAIM ANALYSIS

Application Number: 16306696
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-06
Patent Classification: ["546", "114000"]

Abstract:
It is an object of the present invention to provide a compound inhibiting the binding between ALS-related mutant SOD1 and Derlin-1, a medicament comprising the compound, and a method for treating ALS by administering the medicament to a patient. More specifically, the aforementioned compound is represented by the following formula (1): wherein X represents a sulfur atom or —CH═CH—; A 1  to A 4  each independently represent a carbon atom or a nitrogen atom, and at least one of A 1  to A 4  is a nitrogen atom; R 1  represents a 1,2,3,4-tetrahydroquinolyl group (or a 3,4-dihydro-1(2H)-quinolyl group), a 3,4-dihydro-4,4-dimethyl-1(2H)-quinolyl group, a 2,3,4,5-tetrahydro-1H-1-benzazepinyl group, or a substituent represented by the following formula (2): wherein R 4  represents an unsubstituted or optionally substituted phenyl group, an unsubstituted or optionally substituted pyridyl group, or an unsubstituted or optionally substituted naphthyl group, and R 5  represents any one of a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group (optionally containing an oxygen atom and/or a double bond), or an unsubstituted or optionally substituted aromatic lower alkyl group; R 2  represents a hydrogen atom, a lower alkyl group, a lower acyl group, or an unsubstituted or optionally substituted aromatic lower alkyl group; and R 3  represents a hydrogen atom, or R 2  and R 3  may bind to each other to form a ring.

Claim (Index 3):
The compound according to  claim 2 , or a salt thereof: or a solvate or hydrate thereof, wherein R 2  and R 3  each represent a hydrogen atom.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 99.0
- Lexical Diversity: 2.82105
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['10518725', '11096375', '12187936', '15661786', '13637127']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7912598690907025
- 35 USC 102 Novelty (BERT): 0.5046272280224277
- Combined Prediction Score: 0.7625966049838749
- Mean Citation Score: 270.232816
- Max Citation Score: 283.7195
- Similarity Product: 217.82991473197936

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test