PATENT CLAIM ANALYSIS

Application Number: 15870172
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["800", "003000"]

Abstract:
This disclosure provides non-human animal models for age-related disorders and age-sensitive traits, particularly those caused by senescence-inducing stimuli, wherein the models comprise transgenes selectively expressed by senescent cells. The disclosure further provides methods for identifying therapeutic agents effective for treating or preventing age-related disorders and age-sensitive traits using the animal models, therapeutic agents identified using such methods, pharmaceutical compositions comprising the identified therapeutic agents, and methods of treating or preventing age-related disorders and age-sensitive traits.

Claim (Index 4):
The nucleic acid construct of  claim 1 , wherein the enzyme is a thymidine kinase. The nucleic acid construct of  claim 1 , wherein the particular prodrug is ganciclovir.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 86.0
- Lexical Diversity: 1.82222
- Patent Class: 800.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15067543', '15080991', '14792208', '15827539', '15455684']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6236816862011227
- 35 USC 102 Novelty (BERT): 0.5800792927342663
- Combined Prediction Score: 0.619321446854437
- Mean Citation Score: 353.397666
- Max Citation Score: 534.1656
- Similarity Product: 379.7090061861992

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test