PATENT CLAIM ANALYSIS

Application Number: 15764464
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2019-02
Patent Classification: ["424", "400000"]

Abstract:
The presently disclosed subject matter provides a solid immediate release pharmaceutical multi-particulate dosage form containing at least two different populations of particulates. In certain embodiments, the immediate release pharmaceutical dosage forms contain at least three different populations of multi-particulates. Each population of particulates is designed for a specific function to accomplish the desired combination of abuse deterrence and overdose protection.

Claim (Index 100):
A solid oral immediate release multi-particulate dosage form with abuse deterrent and enhanced overdose protection properties comprising:\n a first population of crush resistant Active Particulates comprising a therapeutically effective amount of an opioid embedded in a polymer matrix, and an acid labile functional coat comprising two functional coat layers over the polymer matrix; wherein the two functional coat layers comprise functional coat layer 1 and functional coat layer 2, and wherein functional coat layer 2 surrounds functional coat layer 1; wherein functional coat layer 1 comprises a nonionic rate-controlling polymer insoluble in physiological fluids and/or organic solvents, and at least one cationic polymer, in a ratio of 80:20, and functional coat layer 2 comprises at least one cationic polymer and, optionally, a nonionic rate-controlling polymer; and a second population of Triggering Particulates comprising an alkaline agent; and wherein the enhanced overdose protection properties comprise resistance to release of the opioid when three or more units of the dosage form are subjected to dissolution in a medium at pH 1.6 for 30 minutes, such that less than about 50% of the opioid is released at 30 minutes.

Metadata:
- Claim Count in Document: 74.0
- Percentile: 90.0
- Lexical Diversity: 1.33333
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15117114', '15271480', '15884745', '14790101', '15271469']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7446095504610043
- 35 USC 102 Novelty (BERT): 0.544528241213438
- Combined Prediction Score: 0.7246014195362477
- Mean Citation Score: 305.646388
- Max Citation Score: 399.10718
- Similarity Product: 355.5654731600058

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test