PATENT CLAIM ANALYSIS

Application Number: 15746241
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-11
Patent Classification: ["435", "199000"]

Abstract:
A non-naturally occurring microorganism having a 1,3-BDO pathway is provided. The microorganism expresses at least one of the following 1,3-BDO pathway enzymes: an aldolase that catalyzes condensation of two acetaldehydes to produce 3-hydroxybutanal; and an aldo-ketoreductase, oxidoreductase, aldehyde reductase or alcohol dehydrogenase that reduces 3-hydroxybutanal to 1,3-BDO. The organism may further express one or more enzymes for producing acetaldehyde. A biosynthetic process involves condensing two acetaldehyde molecules to 3-hydroxybutanal using an enzyme from class aldolases; and selectively reducing 3-hydroxybutanal to 1,3-BDO using an enzyme belonging to the class aldo-ketoreductase, oxidoreductase, aldehyde reductase or alcohol dehydrogenase. The process can further include producing acetaldehyde by a biosynthetic method.

Claim (Index 6):
The non-naturally occurring microorganism of  claim 3 , wherein the exogenous nucleic acid comprises a nucleotide sequence of SEQ ID NO: 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 86.0
- Lexical Diversity: 1.76119
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14692630', '12878980', '14673600', '13597095', '13011818']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.2199355723338243
- 35 USC 102 Novelty (BERT): 0.5563018375793194
- Combined Prediction Score: 0.2535721988583739
- Mean Citation Score: 378.396708
- Max Citation Score: 416.0313
- Similarity Product: 346.76490216194986

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test