PATENT CLAIM ANALYSIS

Application Number: 16211139
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-04
Patent Classification: ["514", "253120"]

Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

Claim (Index 3):
A method of treating liver cancer, comprising administering to the subject a therapeutically effective amount of a compound of formula (I): wherein X is N or CH; A is C(O) and B is NR 5  or A and B together form part of a 5- or 6-membered aromatic ring wherein A is C and B is C or N; R 1  is selected from hydrogen, hydroxyC 1 -C 3 alkyl, haloC 1 -C 3 alkyl, CO 2 H, CH 2 NR 2 R 3 , a 5-membered aromatic heterocyclic ring comprising at least one heteroatom selected from N, O or S, which ring is optionally substituted once or more than once with C 1 -C 3 alkyl; R 2  is C 1 -C 3 alkyl and R 3  is C(O)C 1 -C 3 alkyl or R 2  and R 3  together with the N to which they are attached form a saturated 5- or 6-membered ring optionally comprising one additional heteroatom selected from N, O or S, which ring is optionally substituted once or more than once with R 4 ; R 4  is for each occurrence independently selected from C 1 -C 3 alkyl, C 1 -C 3 alkoxy or two R 4  attached at the same carbon atom form an oxo group; R 5  is selected from hydrogen, C 1 -C 3 alkyl, C 1 -C 3 alkoxyC 1 -C 3 alkyl, (CH 2 ) 0-1 \u2014R 6 ; R 6  is a 4-, 5-, or 6-membered saturated heterocyclic ring comprising at least one heteroatom selected from N, O, or S; R 7  is selected from cyano, haloC 1 -C 3 alkyl; R 8  is selected from hydrogen, NR 9 R 10 , C 1 -C 6 alkoxy; R 9  is hydrogen; R 10  is selected from C 1 -C 6 alkyl, hydroxyC 1 -C 6 alkyl, C 1 -C 4 alkoxyC 1 -C 6 alkyl; in free form or in pharmaceutically acceptable salt form.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 98.0
- Lexical Diversity: 1.4
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15561189', '14972984', '15357195', '14522721', '14858029']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7538890712235995
- 35 USC 102 Novelty (BERT): 0.5450316455244445
- Combined Prediction Score: 0.733003328653684
- Mean Citation Score: 338.9025539999999
- Max Citation Score: 383.7434
- Similarity Product: 318.57245493114

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test