PATENT CLAIM ANALYSIS

Application Number: 15760513
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["536", "022100"]

Abstract:
The present invention provides a method for producing guanidine crosslinked artificial nucleic acid (abbreviated hereinafter as GuNA), and an intermediate compound for the production thereof. Specifically, the present invention provides a method for producing a compound represented by general formula I: (in the formula, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and ring A are as defined in the specification) or a salt thereof wherein a reducing agent is reacted with a compound represented by general formula II: (in the formula, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m, and ring A′ are as defined in the specification).

Claim (Index 20):
A method for preparing a compound represented by general formula II: wherein, R 1  and R 2  represents independently of each other a protecting group for hydroxy group, R 3  and R 4  represent independently of each other a hydrogen atom, or a C 1-6  alkyl group which may be optionally substituted with one or more substituents, each R 5  represents independently a hydrogen atom, or a C 1-6  alkyl group which may be optionally substituted with one or more substituents, each R 6  represents independently a hydrogen atom, or a C 1-6  alkyl group which may be optionally substituted with one or more substituents, m is an integer of 1 to 3, and cycle A\u2032 represents a five to seven membered unsaturated heterocyclic group which may be optionally substituted with one or more substituents selected from the group consisting of a C 1-6  alkyl group which may be optionally substituted with one or more substituents, a C 2-6  alkenyl group which may be optionally substituted with one or more substituents, a C 2-6  alkynyl group which may be optionally substituted with one or more substituents, an amino group which may be optionally substituted with one or more substituents, a hydroxy group which may be optionally substituted with one or more substituents, an oxo group, a thioxo group, and a halogen atom, and the unsaturated heterocyclic group may be further fused with another cycle to form a cycle A\u2032. the method comprising a step of reacting a compound represented by formula IV: wherein, X represents a leaving group, and each of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , m and cycle A\u2032 is the same as defined in the above-mentioned general formula II. with an azide agent.

Metadata:
- Claim Count in Document: 110.0
- Percentile: 90.0
- Lexical Diversity: 2.30508
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['10434387', '14236571', '11265670', '10054300', '13416061']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6427042567667365
- 35 USC 102 Novelty (BERT): 0.4973960601383662
- Combined Prediction Score: 0.6281734371038995
- Mean Citation Score: 275.76572000000004
- Max Citation Score: 277.23288
- Similarity Product: 215.0761583159781

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test