PATENT CLAIM ANALYSIS

Application Number: 16158922
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["250", "282000"]

Abstract:
A sample introduction unit  2  regularly collects a sample from a sample passage  1 . A measurement unit  3  performs an LC/MS analysis for the collected sample. A spectrum matching judgment section  42  performs image recognition referring to mass spectra in a normal condition accumulated in a normal spectrum database  44 , to determine whether a measured mass spectrum is in a normal condition. If the mass spectrum is non-normal, an abnormal peak locator  45  locates a peak which should not be detected in the normal condition, and an MS n  analysis with the located peak selected as the target is performed in the measurement unit  3  under an MS n  analysis execution commander  46 . An identification processor  47  performs substance identification by a library search based on an acquired MS n  spectrum. Upon successful identification, an alert commander  49  issues an alert. Thus, the system can automatically monitor hazardous substances with high accuracy.

Claim (Index 1):
A specific substance monitoring system for monitoring a specific substance which is possibly contained in a sample, using a mass spectrometer capable of an MS n  analysis, where n is an integer equal to or greater than two, the system comprising:\n a) a sample collector for repeatedly collecting, at a predetermined timing, a sample to be subjected to a measurement; b) a mass spectrometry execution controller for performing a mass spectrometric analysis by the mass spectrometer for the sample collected by the sample collector, to acquire a mass spectrum for the sample; c) a mass spectrum judgment section for determining whether or not the mass spectrum acquired under a control of the mass spectrometry execution controller is in a normal condition, using a database created based on mass spectra acquired by performing a mass spectrometric analysis on each of a plurality of samples in the normal condition which are samples that do not contain the specific substance; d) an abnormal peak locator for locating, in a mass spectrum which is judged to be in a non-normal condition by the mass spectrum judgment section, a peak which constitutes a cause of the judgment; e) an MS n  analysis execution controller for performing an MS n  analysis by the mass spectrometer for the sample collected with the sample collector, to acquire an MS n  spectrum, where an ion corresponding to the peak located by the abnormal peak locator is selected as a target in the MS n  analysis; and f) a substance identifier for attempting to identify a substance corresponding to the located peak by performing a library search using the MS n  spectrum acquired under a control of the MS n  analysis execution controller.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 97.0
- Lexical Diversity: 1.76344
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15768157', '14479874', '15027577', '11315162', '13981833']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7177195652000904
- 35 USC 102 Novelty (BERT): 0.4812858432359522
- Combined Prediction Score: 0.6940761930036766
- Mean Citation Score: 218.855006
- Max Citation Score: 233.18599
- Similarity Product: 189.02037878227355

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test