PATENT CLAIM ANALYSIS

Application Number: 15758405
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "578000"]

Abstract:
Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.

Claim (Index 2):
A method of treating Alzheimer's Disease in a subject, the method comprising the steps of:\n a. administering a pharmaceutical composition comprising tramiprosate, valyl-3-amino-1-propanesulfonic acid or a pharmaceutically acceptable salt of either of the foregoing to a subject determined to (i) be APOE4 heterozygous and have moderate Alzheimer's Disease; or (ii) be APOE4/4 homozygous and have mild or mild-moderate Alzheimer's disease; and b. not administering, to the subject, the pharmaceutical composition when the subject is determined to be (i) APOE4 negative; (ii) APOE4 heterozygous and not suffering from moderate Alzheimer's Disease; or (iii) APOE4/4 homozygous and not suffering from mild or mild-moderate Alzheimer's disease.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.13514
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15127565', '14399809', '14059529', '12738396', '13642845']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.4594529288240449
- 35 USC 102 Novelty (BERT): 0.5230045543790572
- Combined Prediction Score: 0.4658080913795461
- Mean Citation Score: 272.551514
- Max Citation Score: 322.8265
- Similarity Product: 254.568479524225

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test