PATENT CLAIM ANALYSIS

Application Number: 15557621
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-03
Patent Classification: ["506", "015000"]

Abstract:
Disclosed herein are compositions and methods for targeted metabolomics profiling to provide absolute quantification of a broad array of metabolic intermediates of fatty acids, amino acids, and carbohydrate metabolism for HFpEF. In an aspect, the disclosure relates to a method for assessing risk of death or a major adverse cardiac event (MACE) in a subject diagnosed with heart failure with preserved ejection fraction (HFpEF). The method may include (a) determining in a sample from the subject the level of each metabolite in at least one factor, wherein the factor is selected from the group consisting of factor 1, factor 3, factor 4, factor 5, factor 10, factor 12, and factor 14; and (b) comparing the level of each metabolite in the sample to a standard, wherein the level of the metabolite in the subject relative to a standard is indicative of the risk of death or MACE in the subject.

Claim (Index 7):
The method of  claim 1  or  2  or  3 , wherein factor 5 consists of ketone related metabolites selected from ketones, \u03b2-hydroxybutyrate, \u03b2-hydroxybutyryl-carnitine, acetylcarnitine, and alanine.

Metadata:
- Claim Count in Document: 11.0
- Percentile: 86.0
- Lexical Diversity: 2.01163
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15066837', '14353969', '13092584', '13570549', '11744789']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6026091097017776
- 35 USC 102 Novelty (BERT): 0.5029774684629827
- Combined Prediction Score: 0.5926459455778982
- Mean Citation Score: 226.27409
- Max Citation Score: 273.40085
- Similarity Product: 217.89995350227653

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test