PATENT CLAIM ANALYSIS

Application Number: 15953152
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["506", "009000"]

Abstract:
The invention relates to a nanoscale antenna including a nucleic acid scaffold having a structure selected from the group consisting of a Holliday junction, a star, and a dendrimer; and a plurality of fluorophores attached to the scaffold and configured as a FRET cascade comprising at least three different types of fluorophores including at least one quantum dot, arranged with (a) a plurality of initial donor fluorophores fixed in exterior positions on the structure, (b) a terminal acceptor fluorophore fixed in a central position on the structure, and (c) a plurality of intermediate fluorophores fixed in positions on the scaffold between the initial acceptor fluorophores and the terminal acceptor fluorophores.

Claim (Index 9):
A method of using a nanoscale antenna, the method comprising:\n providing a nanoscale antenna comprising: a nucleic acid scaffold having a structure selected from the group consisting of a Holliday junction, a star, and a dendrimer; and a plurality of fluorophores attached to the scaffold and configured as a FRET cascade comprising at least three different types of fluorophores, arranged with (a) a plurality of initial donor fluorophores fixed in exterior positions on the structure, (b) a terminal acceptor fluorophore fixed in a central position on the structure, and (c) a plurality of intermediate fluorophores fixed in positions on the scaffold between the initial acceptor fluorophores and the terminal acceptor fluorophores, wherein the plurality of fluorophores comprises at least one form of quantum dot; contacting the nanoscale antenna with an analyte; exciting the antenna with a light source to excite the FRET cascade; and measuring a response of said nanoscale antenna following the excitation, wherein the response indicates a degree of presence in the analyte of the sequence complementary to the toehold sequence.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 91.0
- Lexical Diversity: 1.95238
- Patent Class: 506.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14685836', '15313192', '13202351', '15468767', '13218382']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5104794558949685
- 35 USC 102 Novelty (BERT): 0.6837770213748308
- Combined Prediction Score: 0.5278092124429548
- Mean Citation Score: 316.1000160000001
- Max Citation Score: 682.1455
- Similarity Product: 666.8713216585218

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test