PATENT CLAIM ANALYSIS

Application Number: 16056478
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-11
Patent Classification: ["424", "093700"]

Abstract:
The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.

Claim (Index 12):
The method of  claim 10 , wherein the molecular markers of neurons are selected from the group consisting of Tuj 1 beta-III-tubulin; microtubule associated protein 2 (MAP-2); MAP-1; MAP-5; anti-axonal growth clones; choline acetyltransferase (ChAT); chromagranin A (CgA); dopamine and cAMP-regulated phosphoprotein (DARRP); dopamine transporter (DAT); glutamic acid decarboxylase (GAD); growth associated protein (GAP); HuC protein; HuD protein; alpha-internexin; neuron-specific nuclear protein (NeuN); neurofilament (NF); nerve growth factor (NGF); neuron specific enolase (NSE); peripherin; PH8; protein gene product (PGP); serotonin transporter (SERT); synapsin; neurofibrillary tangle protein (Tau); Thy-1; tyrosine kinase receptor (TRK); tryptophan hydroxylase (TRH); TUC protein; tyrosine hydroxylase (TH); vanilloid receptor like protein (VRL); vesicular GABA transporter (VGAT), vesicular glutamate transporter (VGLUT).

Metadata:
- Claim Count in Document: 5.0
- Percentile: 96.0
- Lexical Diversity: 1.47917
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14181285', '14396180', '15726121', '14356042', '15016934']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7527159157029701
- 35 USC 102 Novelty (BERT): 0.6143385542847503
- Combined Prediction Score: 0.7388781795611482
- Mean Citation Score: 450.77079
- Max Citation Score: 661.95154
- Similarity Product: 458.99871393289567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test