PATENT CLAIM ANALYSIS

Application Number: 16098244
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-05
Patent Classification: ["514", "218000"]

Abstract:
The present invention relates to new compounds of general formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels or dual activity towards subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.

Claim (Index 26):
The compound according to  claim 18 , having one of the following formula (Ia), (Ib), (Ic), (Id), (Ie), (If) or (Ig): wherein X, Y, R 1 , R 2 , m and p are as defined in  claim 18 ; R 4  represents a \u2014CHR 4a R 4b  or a \u2014CH 2 \u2014CHR 4a R 4b  moiety wherein\n R 4a  is a group selected from: \n and R 4b  represents a \u2014(CH 2 ) j \u2014NR 4b\u2032 R 4b\u2033  moiety, wherein j is 0, 1, 2 or 3 and R 4b\u2032  and R 4b\u2033  independently represent a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl; a benzyl group; or a phenethyl group; R 5  and R 6  independently represent a hydrogen atom or a branched or unbranched C 1-6  alkyl radical, preferably methyl; R 7  is a \u2014(CH 2 ) p \u2014NR 7a R 7b  moiety, wherein p is 0, 1, 2 or 3 and wherein\n R 7a  and R 7b  independently represent a hydrogen atom; a branched or unbranched C 1-6  alkyl radical, preferably methyl; a benzyl group optionally substituted by a halogen; a phenethyl group; a \u2014(CH 2 )-cyclopropyl; a pyridinylmethyl group; or \n R 7a  and R 7b , together with the nitrogen atom to which they are attached, form one of the following structures: \n R 8  is a phenethyl group; and R a  is phenyl group optionally substituted with an \u2014OH group.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 98.0
- Lexical Diversity: 1.88235
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14820711', '12680353', '12485108', '13910349', '11828457']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7930502564254063
- 35 USC 102 Novelty (BERT): 0.5395303443358165
- Combined Prediction Score: 0.7676982652164474
- Mean Citation Score: 342.51614000000006
- Max Citation Score: 362.67856
- Similarity Product: 242.83259777163505

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test