PATENT CLAIM ANALYSIS

Application Number: 16196037
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-03
Patent Classification: ["424", "045000"]

Abstract:
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising a phosphodiesterase type 5 inhibitor and/or a salt thereof, and optionally, a hostile biophysical environment and/or a nitric oxide donor. In some cases, the composition may be stabilized using a combination of a stabilization polymer (such as xanthan gum, KELTROL® BT and/or KELTROL® RD), propylene glycol, and a polysorbate surfactant such as Polysorbate 20, which combination unexpectedly provides temperature stability to the composition, e.g., at elevated temperatures such as at least 40° C. (at least about 104° F.), as compared to compositions lacking one or more of these.

Claim (Index 181):
The composition of  claim 180 , wherein the composition is stable when exposed to a temperature of 40\u00b0 C. for at least about 4 weeks.

Metadata:
- Claim Count in Document: 79.0
- Percentile: 98.0
- Lexical Diversity: 1.65909
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15160179', '15159926', '13977461', '15290504', '15342309']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.786237161914231
- 35 USC 102 Novelty (BERT): 0.5483868622024527
- Combined Prediction Score: 0.7624521319430532
- Mean Citation Score: 348.6241300000001
- Max Citation Score: 349.1269
- Similarity Product: 265.2205312828183

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test