PATENT CLAIM ANALYSIS

Application Number: 15922676
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["435", "007100"]

Abstract:
Provided herein is technology relating to the biological process of protein ubiquitination and particularly, but not exclusively, to compositions and methods for studying protein ubiquitination and developing therapeutics to modulate protein ubiquitination.

Claim (Index 21):
A method of screening for modulators of E3 ligase activity, the method comprising:\n a) providing a test composition comprising an E3 ligase, a ubiquitin C-terminal thioester fluorophore, and a molecule to test for the ability to modulate the activity of the E3 ligase; and b) monitoring the fluorescence of the fluorophore in the test composition.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 90.0
- Lexical Diversity: 1.34615
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14856251', '15436399', '11685122', '14268977', '15086719']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5898377096218628
- 35 USC 102 Novelty (BERT): 0.661791424119859
- Combined Prediction Score: 0.5970330810716624
- Mean Citation Score: 452.16141000000016
- Max Citation Score: 820.1045
- Similarity Product: 596.0819842712582

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test