PATENT CLAIM ANALYSIS

Application Number: 15979313
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-04
Patent Classification: ["435", "136000"]

Abstract:
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.

Claim (Index 77):
The method of  claim 76 , wherein said organism comprises at least one exogenous nucleic acid encoding a MAA pathway enzyme expressed in a sufficient amount to produce MAA, wherein said MAA pathway comprises\n (1) (i) a succinyl-CoA transferase, ligase, or synthetase; (ii) a methylmalonyl-CoA mutase; (iii) a methylmalonyl-CoA epimerase; (iv) a methylmalonyl-CoA reductase (aldehyde forming); (v) a methylmalonate semialdehyde reductase; and (vi) a 3-hydroxyisobutyrate dehydratase; (2) (i) a succinyl-CoA transferase, ligase, or synthetase; (ii) a methylmalonyl-CoA mutase; (iii) a methylmalonyl-CoA reductase (aldehyde forming); (iv) a methylmalonate semialdehyde reductase; and (v) a 3-hydroxyisobutyrate dehydratase; or (3) (i) a succinyl-CoA transferase, ligase, or synthetase; (ii) a methylmalonyl-CoA mutase; (iii) a methylmalonyl-CoA reductase (alcohol forming); and (iv) a 3-hydroxyisobutyrate dehydratase.

Metadata:
- Claim Count in Document: 59.0
- Percentile: 93.0
- Lexical Diversity: 1.4375
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15133150', '14071339', '14107832', '13975678', '14071318']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7014520786140329
- 35 USC 102 Novelty (BERT): 0.6479083451342311
- Combined Prediction Score: 0.6960977052660527
- Mean Citation Score: 657.7333659999998
- Max Citation Score: 754.3332
- Similarity Product: 577.1905103734017

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test