PATENT CLAIM ANALYSIS

Application Number: 15773466
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["514", "04400A"]

Abstract:
A pharmaceutical composition can be provide for treating or preventing heart failure. Additionally, siRNA and a vector expressing said siRNA can be provided that can be used in the pharmaceutical composition for treating or preventing heart failure. For example, a pharmaceutical composition can be provided for treating or preventing heart failure that contains a DNA sequence encoding RNA containing a sense strand sequence of consecutive 18 to 29 nucleotides from angiopoietin-like protein 2 (ANGPTL2) mRNA or the alternative splicing type RNA thereof and an antisense strand sequence complementary to the sense strand sequence under control of a promoter, and a pharmaceutically acceptable carrier.

Claim (Index 28):
A pharmaceutical composition for treating or preventing heart failure, comprising an expression vector containing a DNA sequence encoding RNA comprising a sense strand sequence of consecutive 18 to 29 nucleotides from angiopoietin-like protein 2 (ANGPTL2) mRNA or the alternative splicing type RNA thereof, and an antisense strand sequence complementary to the sense strand sequence under control of a promoter, and a pharmaceutically acceptable carrier,\n wherein the sense strand sequence and antisense strand sequence are adapted for use in preparing siRNA, which siRNA, when transduced into animal cell, suppresses expression of the angiopoietin-like protein 2 gene in the cell and has a silencing effect on the angiopoietin-like protein 2 gene.

Metadata:
- Claim Count in Document: 8.0
- Percentile: 97.0
- Lexical Diversity: 1.7619
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14342867', '12811306', '13702033', '12096216', '13389236']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7785873956981039
- 35 USC 102 Novelty (BERT): 0.5267379372541194
- Combined Prediction Score: 0.7534024498537054
- Mean Citation Score: 307.718864
- Max Citation Score: 339.27847
- Similarity Product: 216.52882894131423

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test