PATENT CLAIM ANALYSIS

Application Number: 16250470
Application Type: Utility
Filing Date: 2019-01
Publication Date: 2019-05
Patent Classification: ["514", "728000"]

Abstract:
A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic injury, stroke, Huntington's disease, Epilepsy, Multiple Sclerosis (MS), Lupus, Type-1 and Type-2 diabetes, Maturity Onset Diabetes of the Young (MODY), myasthenia gravis (MG), rheumatoid arthritis (RA), Graves' disease, Guillain-Barré syndrome (GBS), metabolic syndrome, Muscular Dystrophy or Duchenne Muscular Dystrophy (DMD), severe burns, aging, Amyotrophic Lateral Sclerosis (ALS), Friedreich's Ataxia, Batten Disease, Alzheimer's disease, optic neuritis, Leber's hereditary optic neuropathy (LHON), autism, Rett syndrome, Batten Disease, Angelman's Syndrome, Leigh disease, Fragile-X Syndrome, depression, Parkinson's disease, mitochondrial diseases, developmental disorders, metabolic disease disorders and/or autoimmune disorders by inducing endogenous BDNF expression with DNP treatment to protect from neuromuscular dysfunction/disorders and/or neurodegeneration and/or muscle wasting. DNP was administered to mice daily over a range of doses, and subsequently BDNF expression in the brain showed a dose dependent and non-linear increase in expression.

Claim (Index 63):
The pharmaceutical composition of  claim 61 , wherein the effective dose of 2,4-dinitrophenol (DNP) is in the range of about 0.1 mg/kg of body weight to about 1 mg/kg of body weight.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 99.0
- Lexical Diversity: 1.83478
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15357412', '15707239', '15002531', '15451938', '12134707']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8487121457764356
- 35 USC 102 Novelty (BERT): 0.6522937513381458
- Combined Prediction Score: 0.8290703063326066
- Mean Citation Score: 548.8245999999998
- Max Citation Score: 699.4024
- Similarity Product: 586.7376986321925

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test