PATENT CLAIM ANALYSIS

Application Number: 16140023
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-06
Patent Classification: ["435", "007320"]

Abstract:
Described herein are assays for identifying piericidins and piericidin compositions.

Claim (Index 31):
A method of selecting a bacterial type III secretion system inhibitor, the method comprising:\n infecting a mammalian cell with a Gram negative bacterium, wherein the mammalian cell comprising an NF-\u03baB reporter, and wherein the Gram negative bacterium is characterized as having a type III secretion system; contacting the mammalian cell with a screening compound; measuring a first expression level of the NF-\u03baB reporter in the presence of the screening compound, wherein the screening compound is provided in a vehicle; measuring a second expression level of the NF-\u03baB reporter in the presence of the vehicle without the screening compound; and identifying the screening compound as a bacterial type III secretion system inhibitor if the first expression level is less than the second expression level.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 97.0
- Lexical Diversity: 1.0
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15039116', '13263071', '12742043', '14269459', '14232445']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5871052525233624
- 35 USC 102 Novelty (BERT): 0.579632128388796
- Combined Prediction Score: 0.5863579401099058
- Mean Citation Score: 289.035212
- Max Citation Score: 559.1578
- Similarity Product: 383.0967834300516

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test