PATENT CLAIM ANALYSIS

Application Number: 15940158
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["435", "007100"]

Abstract:
Certain embodiments are directed to marker peptides or marker peptide antibodies can be used in producing diagnostic kits or used in diagnostic methods for Alzheimer's disease. The antibodies and/or marker peptides can be used in immunohistochemical and biochemical methods for qualitative and quantitative analysis of marker peptide levels and/or localization in brain samples and CSF samples.

Claim (Index 21):
A method for screening a therapeutic agent for Alzheimer's disease, the method comprising the steps of contacting cells expressing an approximately 12 kDa APP Alzheimer's disease marker peptide consisting of an amino acid sequence of SEQ ID NO:2, SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, or SEQ ID NO:10 with an agent to be screened; and determining a change in the amount or stability of the marker peptide or the toxicity of the marker peptide to the cell.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 90.0
- Lexical Diversity: 1.59459
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['09980881', '14810760', '15342629', '13582308', '15207836']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5950005589434127
- 35 USC 102 Novelty (BERT): 0.5234385135787214
- Combined Prediction Score: 0.5878443544069436
- Mean Citation Score: 332.7754740000001
- Max Citation Score: 346.69672
- Similarity Product: 250.461235830903

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test