PATENT CLAIM ANALYSIS

Application Number: 15763407
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-10
Patent Classification: ["514", "054000"]

Abstract:
The invention provides a low-molecular-weight (15 kDa) over-sulfated exopolysaccharide (GYS15) prepared from a marine native exopolysaccharide excreted by a mesophilic marine bacterium from a deep-sea hydrothermal environment, and relates to the use of this low-molecular-weight over-sulfated exopolysaccharide for the prevention or inhibition of metastases formation.

Claim (Index 16):
A method for preventing or inhibiting metastases formation in a subject, comprising a step of administering to said subject a therapeutically effective amount of a 15 kDa over-sulfated exopolysaccharide, wherein said 15 kDa over-sulfated exopolysaccharide is obtained by a method comprising the following steps:\n (a) a step consisting of free-radical depolymerization of a marine native exopolysaccharide (EPS) from the strain GY785 of the  Alteromonas  genus so as to obtain a depolymerized EPS having a molecular weight of 5,000 to 100,000 g/mol; (b) a subsequent step consisting of sulfation of the depolymerized EPS to obtain an over-sulfated depolymerized EPS, comprising adding to the depolymerized EPS at least one sulfation agent in an amount sufficient to obtain a sulfated polysaccharide having a degree of sulfate-group substitution of between 10% and 45% by weight relative to the total weight of the over-sulfated depolymerized EPS; and (c) a subsequent step consisting of isolating the 15 kDa over-sulfated exopolysaccharide (GYS15) from the over-sulfated depolymerized EPS.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 90.0
- Lexical Diversity: 1.34211
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['12986820', '14052133', '14822477', '11629544', '15031020']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7550481234646583
- 35 USC 102 Novelty (BERT): 0.5007248097306538
- Combined Prediction Score: 0.7296157920912579
- Mean Citation Score: 234.10526600000003
- Max Citation Score: 249.93044
- Similarity Product: 178.33578767400502

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test