PATENT CLAIM ANALYSIS

Application Number: 16058194
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2020-02
Patent Classification: ["null", "null"]

Abstract:
A method for parallel accumulation and serial fragmentation of ions, wherein ions are injected into a device capable of serial ejection using a pseudopotential barrier created by an RF voltage. In all instances, the ions may be filtered prior to accumulation in the device capable of serial ejection. In some cases this filtering may take the form of discrete isolation windows using isolation waveforms with multiple notches. In some cases these waveforms may be applied to a quadrupole mass filter. Following accumulation of the precursor ions, the initial population may be serially ejected using a pseudopotential barrier created by an RF voltage. Following serial ejection, the individual precursor ion populations are analyzed. In some cases, this analysis might involve additional rounds of ion isolation and manipulation (e.g., MSn, CID, ETD, etc.).

Claim (Index 21):
A mass spectrometer system comprising:\n (i) an ionization source; (ii) a mass filter apparatus configured to receive ions from the ionization source; (iii) a fragmentation or reaction cell configured to receive ions filtered according to mass-to-charge ratio (m/z) by the mass filter and to trap and/or fragment or react the received ions so as to thereby generate product ions; (iv) a mass analyzer configured to receive, mass analyze and detect the product ions; (v) an ion guide configured to receive the filtered ions from the mass filter and to transmit the filtered ions to the fragmentation or reaction cell, the ion guide comprising:\n an entrance end and an ion exit end; \n an axis extending between the ion entrance and exit ends; and \n a sequence of sections disposed along the axis from the entrance lens to the exit lens, each section comprising:\n a stack of two or more plate electrodes, each plate electrode comprising an aperture, the plurality of apertures of all plate electrodes defining an ion channel through the ion guide; \n \n (vi) one or more power supplies electrically coupled to the ion guide, the fragmentation or reaction cell and the mass analyzer, wherein the one or more power supplies are configured to:\n supply a radio-frequency (RF) confining voltage to the stack of plate electrodes, a phase difference of the RF confining voltage being 180 degrees between each pair of adjacent plate electrodes; \n supply an auxiliary RF voltage waveform to all plate electrodes of a section, each of a phase, amplitude and frequency of the provided auxiliary RF voltage being identical among all electrodes of the section; and \n supply a DC potential difference between the section to which the auxiliary RF voltage is provided and a second section that is adjacent thereto.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 96.0
- Lexical Diversity: 1.89873
- Patent Class: nan
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11409169', '12111484', '11133724', '11394504', '14631959']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.566679227528981
- 35 USC 102 Novelty (BERT): 0.5103040746816649
- Combined Prediction Score: 0.5610417122442494
- Mean Citation Score: 300.9517
- Max Citation Score: 308.9958200000001
- Similarity Product: 236.84862843435653

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test