PATENT CLAIM ANALYSIS

Application Number: 16054512
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2018-12
Patent Classification: ["514", "210000"]

Abstract:
The present invention provides bicyclic heterocyclyl kinase enzyme inhibitor compounds of formula (I), which are therapeutically useful as kinase inhibitors, particularly IRAK4 inhibitors. wherein A, Y, Z, X 1 , X 2 , X 3 , R 1 , R 3 , ‘m’, ‘n’ and ‘p’ have the meanings given in the specification and pharmaceutically acceptable salt or stereoisomer thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder mediated by kinase enzyme, particularly IRAK4 enzyme. The present invention also provides pharmaceutical composition comprising at least one of the compounds of compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

Claim (Index 40):
The method of  claim 39 , wherein\n M is R 10  is tertiary butyl; Q 1  is 2-dicyclohexylphosphino-2\u2032,4\u2032,6\u2032-triisopropylbiphenyl (xphos), 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (xantphos), trans-N,N\u2032-dimethylcyclohexane-1,2-diamine or is absent; Q 2  is tris(dibenzylideneacetone)dipalladium(0) (Pd 2 (dba) 3 ), bis(triphenylphosphine)palladium(II) dichloride (Pd(PPh 3 ) 2 (Cl) 2 ), copper iodide (CuI), or is absent; B is a base and the base is a cesium carbonate, sodium carbonate, or potassium phosphate; and Sv is toluene, dimethoxyethane (DME), dioxane, water, or a combination thereof.

Metadata:
- Claim Count in Document: 77.0
- Percentile: 96.0
- Lexical Diversity: 1.79221
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15667173', '15111000', '15110309', '13006217', '12236317']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8521416841596091
- 35 USC 102 Novelty (BERT): 0.5941240897638409
- Combined Prediction Score: 0.8263399247200324
- Mean Citation Score: 483.605628
- Max Citation Score: 641.4711
- Similarity Product: 413.067199799037

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test