PATENT CLAIM ANALYSIS

Application Number: 15744551
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-01
Patent Classification: ["424", "186100"]

Abstract:
Disclosed are compositions and methods for related to mutant influenza viruses with increased fidelity.

Claim (Index 34):
A method of increasing the immunogenicity of an attenuated influenza vaccine comprising obtaining an attenuated influenza vaccine viral strain and generating a mutation in the PB1 or PA subunit of the RNA polymerase of the influenza virus, wherein the mutation increases the fidelity of the RNA polymerase; and wherein an increase in fidelity of the polymerase increases the stability of the virus strain in a subject and reduces the amount mutant viruses formed during transcription of the virus thereby increasing the abundance of a single strain and as a result increases the immune response to the immunizing strain.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 86.0
- Lexical Diversity: 1.0
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14905320', '15568836', '14745236', '13124581', '11729557']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6921882025632675
- 35 USC 102 Novelty (BERT): 0.5245356018353281
- Combined Prediction Score: 0.6754229424904736
- Mean Citation Score: 321.539898
- Max Citation Score: 338.27835
- Similarity Product: 241.80128399267792

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test