PATENT CLAIM ANALYSIS

Application Number: 16159114
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-01
Patent Classification: ["435", "006120"]

Abstract:
The present invention provides a method of assessing whether an individual is at high risk or low risk of inflammatory bowel disease (IBD) progression by determining the expression level of two or more genes in a whole blood sample. Also provided are methods for treating IBD in an individual who is determined to be at high risk or low risk for IBD progression, and kits for assessing whether an individual is at high risk or low risk for IBD progression. Arrays, and methods of providing arrays, of patient-identified selected gene expression products from a whole blood sample of a patient are also provided.

Claim (Index 7):
An array of quantified selected gene expression products, said array comprising a plurality of quantified selected gene expression products of cDNA of a whole blood sample of a subject, said plurality comprising quantified selected gene expression products of three or more genes selected from the group consisting essentially of: ARRDC4, GBP5, P2RY14, LINC01136, VTRNA1-1, IL18RAP, HP, NUDT7, GZMH, TRGC2, GZMK, LGALSL, FCRL5, IFI44L, LY96, and TRGV3, wherein for each quantified selected gene expression product, the quantified amount of gene expression product for a given selected gene is higher or lower than a control for each selected gene, wherein said control comprises the median quantified amount of gene expression product of said selected gene among a group of subjects.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 97.0
- Lexical Diversity: 1.85
- Patent Class: 435.0
- Transitional Phrase Type: half
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15651746', '14825480', '15426923', '13821404', '15271687']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5330989163606933
- 35 USC 102 Novelty (BERT): 0.7478821405074068
- Combined Prediction Score: 0.5545772387753647
- Mean Citation Score: 364.567182
- Max Citation Score: 1128.0154
- Similarity Product: 834.5863137199162

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test