PATENT CLAIM ANALYSIS

Application Number: 16067444
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["544", "326000"]

Abstract:
Disclosed in the present invention are an acrylanilide compound represented by general formula (I) and a pharmaceutically acceptable salt thereof. The acrylanilide compound and the pharmaceutically acceptable salt thereof are used for treating clinical diseases by mainly acting on EGFR family casein kinases.

Claim (Index 2):
The compound or the pharmaceutically acceptable salts, solvates or prodrugs thereof according to  claim 1 , wherein the compound of formula (I) is the compound of formula (IIa), (IIb) or (IIc), wherein, R 1  is selected from the following a) or b): a) when the compound of formula (I) is the compound of formula IIa or IIb, R 1  is \u2014NR 5 R 6 , \u2014OR 5  or \u2014SR 5 ; b) when the compound of formula (I) is the compound of formula IIc, R 1  is \u2014NR 5 R 6 , or R 1  is \u2014CR 5 R 6  (and R 5  and R 6  form cycle with the carbon atoms attached to them); R 2  is alkoxy; R 3  is selected from the group consisting of hydrogen, N(R y )(R z ), \u2014N(R v )R u N(R y )(R z ), \u2014OR u OR 6 , and \u2014OR u N(R y )(R z ); R 4  and R\u2032 4  are each selected from the group consisting of hydrogen, halogen, alkyl and haloalkyl; R 5  and R 6  are selected from any one of the a), b) and c) below: a) R 5  is optionally substituted aryl group; when substituted, the substituent is selected from 1-5 R 7  groups; wherein each R 7  group is independently selected from the group consisting of hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, hydroxyl, amino, haloalkoxy, cycloalkyl, cycloalkylalkyl, hydroxylalkyl, haloalkyl, aryl, aryl alkyl, heterocyclyl, heterocyclylalkyl, heteroaryl and heteroaryl-alkyl; wherein, the alkyl, alkenyl, alkynyl, alkoxy, amino, haloalkoxy, cycloalkyl, cycloalkylalkyl, hydroxylalkyl, haloalkyl, aryl, aryl alkyl, heterocyclyl or heteroaryl or heteroarylalkyl is optionally substituted with 1-5 groups selected from halogen, alkyl, alkenyl, alkynyl, aryl, hydroxyl, alkoxy, haloalkoxy, cycloalkyl, ester group and cyano; R 6  is selected from hydrogen and alkyl; b) R 5  and R 6  form fused aromatic ring together with the nitrogen atoms attached to them, and the ring contains 0-4 heteroatoms independently selected from O, S and N; when substituted, the substituent is optionally 1-4 groups selected from halogen, haloalkyl, alkyl, alkenyl and cyano; c) R 5  and R 6  form fused aromatic ring together with the carbon atoms attached to them, and the ring contains 0-4 heteroatoms independently selected from O, S and N; when substituted, the substituent is optionally 1-4 groups selected from halogen, haloalkyl, alkyl, alkenyl and cyano; R u  is each independently selected from alkylene; R v  is selected from hydrogen and alkyl; Ry and Rz are each independently selected from the following a) or b): a) R y  and R z  are each selected from hydrogen, alkyl and haloalkyl; b) R y  and R z  form heterocyclyl together with the nitrogen atoms attached to them, and the ring contains 0-4 heteroatoms independently selected from O, S and N; and the ring is optionally substituted with 1-4 groups selected from halogen, haloalkyl, alkyl, alkoxyalkyl, alkylhydroxyl, NR 6 R 6  and heterocyclyl.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 94.0
- Lexical Diversity: 1.30556
- Patent Class: 544.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['11728897', '15745187', '12865339', '12755301', '13386645']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8562853499831129
- 35 USC 102 Novelty (BERT): 0.551937526108088
- Combined Prediction Score: 0.8258505675956105
- Mean Citation Score: 420.294502
- Max Citation Score: 433.8232
- Similarity Product: 329.1515452587128

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test