PATENT CLAIM ANALYSIS

Application Number: 16177344
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-05
Patent Classification: ["514", "001100"]

Abstract:
A method of treatment of pain in a person with a D peptide chemokine receptor antagonist (CRA), and a pharmaceutically acceptable carrier is disclosed. Because chemokines desensitize opiate receptors and enhance the perception of pain said D-peptide CRA, given with a suboptimal dose of an opioid, such as morphine, will restore opioid analgesic efficacy by blocking the cognate chemokine ligand from binding to its receptor and desensitizing the opioid receptor. This strategy of combining a suboptimal dose of morphine with a CRA enhances the potency of morphine, permitting use of lower doses of morphine to obtain equivalent and near maximal analgesia. Lower morphine (opioid) doses have less risk of adverse effects, and potentially also of development of tolerance and dependence.

Claim (Index 10):
A method of pain treatment wherein said chemokine receptor antagonist may be combined, as in a pill or liquid with an opioid to provide pain relief at lower opioid dose.

Metadata:
- Claim Count in Document: 7.0
- Percentile: 97.0
- Lexical Diversity: 1.65432
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11821525', '10537704', '12480059', '14557576', '11579615']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7789671126014953
- 35 USC 102 Novelty (BERT): 0.50590725935616
- Combined Prediction Score: 0.7516611272769618
- Mean Citation Score: 230.591084
- Max Citation Score: 244.40012
- Similarity Product: 163.16490846182344

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test