PATENT CLAIM ANALYSIS

Application Number: 15970952
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "243000"]

Abstract:
We describe a method of monitoring the state of a cell, tissue, organ or organism. The method comprises establishing, for a sample of micro-particles from the cell, tissue, organ or organism, a ratio. The ratio is of a selected polypeptide in microparticles which comprise GM1 gangliosides, preferably which bind to Cholera Toxin B (CTB) (“GM1 ganglioside microparticle polypeptide”) to the selected polypeptide in microparticles which comprise exposed phos—photidylserine, preferably which bind to Annexin V (“Annexin V microparticle polypeptide”). The GM1 ganglioside microparticle polypeptide to Annexin V microparticle polypeptide ratio so established may be indicative of the state of the cell, tissue, organ or organism.

Claim (Index 1):
The method of  claim 1 ,\n (a) further comprising a step of selecting microparticles by size; (b) in which the microparticles comprise CD9+ microparticles; (c) in which the sample is selected from the group consisting of urine, blood, tears, saliva, bronchoaveolar fluid, tumoral effusions, epididymal fluid, amniotic fluid and milk; or (d) in which the microparticles comprise microvesicles, exosomes, ectosomes or apoptotic bodies.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 93.0
- Lexical Diversity: 2.37037
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15219820', '14361500', '14773677', '14438172', '15738564']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5959852372246295
- 35 USC 102 Novelty (BERT): 0.6067462003388816
- Combined Prediction Score: 0.5970613335360547
- Mean Citation Score: 405.409234
- Max Citation Score: 619.3103
- Similarity Product: 449.2428010474444

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test