PATENT CLAIM ANALYSIS

Application Number: 15758098
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["514", "312000"]

Abstract:
The present invention relates in a first aspect to compounds for use in the treatment of leukodystrophy whereby these compounds are quinoline derivatives, e.g. laquinimod. In a further aspect, the present invention relates to methods for the treatment of Leukodystrophy, in particular, peroxisomal disorders including Zellweger syndrome.

Claim (Index 25):
The method of  claim 24 , wherein the compound is a compound of general formula (III) wherein R 13  is selected from methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl and allyl; R 12  is selected from hydrogen and pharmaceutically acceptable inorganic and organic cations; R 1  and R 2  are the same or different and selected from hydrogen, methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl, methoxy, ethoxy, chloro, bromo, CF 3 , and OCH X F Y ; wherein x=0-2, y=1-3 with the proviso that x+y=3; or R 1  and R 2  taken together are methylenedioxy; R 15  is hydrogen, a straight or branched, saturated or unsaturated C 1 -C 6 -alkyl or -alkenyl, a cyclic C 3 -C 6 -alkyl, a straight or branched C 1 -C 6 -alkoxy, a cyclic C 3 -C 6 -alkoxy, fluoro, chloro, bromo, trifluoromethoxy or trifluoromethyl; and R 16  is hydrogen, fluoro or chloro, with the proviso that R 15  is fluoro or chloro only when R 16  is fluoro or chloro and any tautomer thereof.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 90.0
- Lexical Diversity: 1.54286
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['13417030', '14182994', '13417028', '11482926', '16301711']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7162544984766797
- 35 USC 102 Novelty (BERT): 0.4872483796882609
- Combined Prediction Score: 0.6933538865978378
- Mean Citation Score: 176.222894
- Max Citation Score: 180.24554
- Similarity Product: 133.3999759637797

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test