PATENT CLAIM ANALYSIS

Application Number: 16026421
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "252100"]

Abstract:
A method of treating cancer in a subject includes administering to the subject a therapeutically effective amount of a small molecule agonist of EphA2 receptor protein, the small molecule having a general formula: A-L-X-Z (I).

Claim (Index 19):
A method of treating prostate cancer in a subject, comprising:\n administering to the subject a therapeutically effective amount of a small molecule agonist of EphA2 receptor protein, the small molecule having general formula:\n A-L-X-Z\u2003\u2003(I), \n wherein A is a substituted or unsubstituted aryl or heteroaryl; L is wherein \u03b1 and \u03b2 can each individually represent (CH 2 ) m  (m is an integer from 2 to 4) and \u03b2 is optionally present;\n X is C\u2550O or SO 2 ; and \n Z is \u2014Y\u2014(R 1 ) n , wherein Y is a substituted or unsubstituted C 1 -C 24  alkyl, C 2 -C 24  alkenyl, C 2 -C 24  alkynyl, aryl, heteroaryl, heterocycloalkenyl containing from 5-6 ring atoms, C 6 -C 24  alkaryl, C 6 -C 24  aralkyl, C 1 -C 24  alkoxy, C 2 -C 24  alkenyloxy, C 2 -C 24  alkynyloxy, C 5 -C 20  aryloxy, acyl, acyloxy (\u2014O-acyl), C 2 -C 24  alkoxycarbonyl (\u2014(CO)\u2014O-alkyl), C 6 -C 20  aryloxycarbonyl (\u2014(CO)\u2014O-aryl), C 2 -C 24  alkylcarbonato (\u2014O\u2014(CO)\u2014O-alkyl), C 6 -C 20  arylcarbonato (\u2014O\u2014(CO)\u2014O-aryl), wherein Z is not a 1,4 benzodioxin when A is an 4-Amino-6,7-dimethoxy-2-quinazolinyl, R 1  is optionally present and if present is a structurally similar monomer of A-L-X and is linked to X via Y, and n is an integer from 0-10, thereby forming a dimer, trimer, or dendrimer molecule of A-L-X monomers, and pharmaceutically acceptable salts thereof.

Metadata:
- Claim Count in Document: 33.0
- Percentile: 95.0
- Lexical Diversity: 1.29032
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15237494', '13461098', '11577770', '12373574', '10652407']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7819262510587298
- 35 USC 102 Novelty (BERT): 0.5486329152635435
- Combined Prediction Score: 0.7585969174792112
- Mean Citation Score: 376.017902
- Max Citation Score: 428.74655
- Similarity Product: 297.83372071524263

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test