PATENT CLAIM ANALYSIS

Application Number: 16390989
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-08
Patent Classification: ["436", "131000"]

Abstract:
Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.

Claim (Index 1):
A method for determining the amount of a vitamin D metabolite in a sample by tandem mass spectrometry, comprising:\n (a) generating a protonated and dehydrated precursor ion of said vitamin D metabolite by atmospheric pressure chemical ionization (APCI); (b) generating one or more fragment ions of said precursor ion; and (c) detecting the amount of one or more of said ions generated in step (a) or (b) or both and relating the detected ions to the presence or amount of said vitamin D metabolite in said sample; wherein said vitamin D metabolite is 25-hydroxyvitamin D 3  or 25-hydroxyvitamin D 2 .

Metadata:
- Claim Count in Document: 11.0
- Percentile: 100.0
- Lexical Diversity: 2.22857
- Patent Class: 436.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15848325', '13115916', '15388844', '13327650', '13871457']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7537008832521409
- 35 USC 102 Novelty (BERT): 0.5807488861552048
- Combined Prediction Score: 0.7364056835424473
- Mean Citation Score: 481.07674
- Max Citation Score: 483.87936
- Similarity Product: 476.3415297513199

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test