PATENT CLAIM ANALYSIS

Application Number: 16355352
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-09
Patent Classification: ["514", "263200"]

Abstract:
The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R 1 , R 4  and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

Claim (Index 2):
The compound of  claim 1 , wherein A is: wherein:\n E is a five membered or a six membered heteroaryl ring wherein one ring carbon atom is optionally substituted with oxo; \n G is a six membered heteroaryl ring having one ring carbon atom substituted with oxo; \n one to three of Y 1 , Y 2 , Y 3 , Y 4 , Y 5  and Y 6  are nitrogen, and the other of Y 1 , Y 2 , Y 3 , Y 4 , Y 5  and Y 6  are carbon, and one of Y 1 , Y 2 , Y 3  and Y 4  may be \u2014C(O)\u2014 or \u2014C(S)\u2014; \n one or two of Z 1 , Z 2 , Z 3 , Z 4  and Z 5  are nitrogen and the other of Z 1 , Z 2 , Z 3 , Z 4  and Z 5  are carbon; \n each R 2  is independently; H, D; \u2014C 1-4  alkyl; \u2014C 1-4  haloalkyl; \u2014CN; halo; haloC 1-4 alkoxy; C 1-4  alkoxy; \u2014OH; \u2014SO 2 \u2014C 1-4 alkyl; \u2014C 1-4 CN, C 1-4  aldehyde; C 1-4  ketone; benzylamino; or NR 14 R 15 ; \n p is 0, 1 or 2; \n each R 3  is independently: H; D; \u2014C 1-4  alkyl; \u2014C 1-4  haloalkyl; \u2014CN; halo; or NR 14 R 15 ; \n q is 0 or 1; \n R 14  and R 15  are each independently: H; substituted or unsubstituted \u2014C 1-4  alkyl; substituted or unsubstituted \u2014C(O)\u2014C 1-4  alkyl; substituted or unsubstituted C 3-6  cycloalkyl; substituted or unsubstituted 3- to 6-membered heterocycloalkyl; substituted or unsubstituted \u2014C 1-4  heteroalkyl; \u2014C(O)NR 16 R 17 ; substituted or unsubstituted \u2014C 1-4  alkyl-C(O)NR 16 R 17 ; substituted or unsubstituted phenyl; or substituted or unsubstituted benzyl; \n or R 14  and R 15  together with the atoms to which they are attached may form a 4-, 5-, 6- or 7-membered ring that optionally includes one additional heteroatom selected from O, N and S; and \n R 16  and R 17  each are independently H and C 1-4  alkyl.

Metadata:
- Claim Count in Document: 19.0
- Percentile: 99.0
- Lexical Diversity: 1.56
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14118113', '16033632', '15298686', '15459141', '15945852']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8081588471609866
- 35 USC 102 Novelty (BERT): 0.5226188933968398
- Combined Prediction Score: 0.779604851784572
- Mean Citation Score: 320.109122
- Max Citation Score: 323.93375
- Similarity Product: 228.16431833490728

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test