PATENT CLAIM ANALYSIS

Application Number: 16079868
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["514", "04400A"]

Abstract:
Aberrantly expressed piRNAs, genetically associated piRNAs and their relationship with cancer risk and severity are provided. Compositions and methods of using piRNA for treating cancer are provided. Methods of diagnosing subjects and determining the efficacy of active agents for treating cancer are also provided. Methods of correlating variant piRNA to cancer are also disclosed.

Claim (Index 29):
A method for determining therapeutic efficacy of an active agent in a subject comprising determining the levels of a piRNA in a first biological sample before or during treatment with an active agent and a second biological sample taken at a time period after one or more treatments with the active agent wherein an increase in the level of piRNA in the second sample compared to the first sample is indicative of an efficacious active agent if a reduced level of the piRNA relative to normal tissue correlates with the cancer.

Metadata:
- Claim Count in Document: 6.0
- Percentile: 96.0
- Lexical Diversity: 1.63889
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13470233', '15313555', '14112296', '14020811', '15422725']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7366749851313125
- 35 USC 102 Novelty (BERT): 0.5091088613060342
- Combined Prediction Score: 0.7139183727487847
- Mean Citation Score: 233.341736
- Max Citation Score: 247.30536
- Similarity Product: 154.54127750626088

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test