PATENT CLAIM ANALYSIS

Application Number: 16060641
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "210210"]

Abstract:
The present invention relates to LpxC antibacterial compounds of Formula (IA): corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation, treatment methods and uses for bacterial infections, especially those caused by gram-negative bacteria.

Claim (Index 10):
A compound of Formula (V): wherein:\n each R 1  or R 2  independently is selected from hydrogen, hydroxy or straight or branched C 1 -C 6  alkyl; \n R 3  is \u2014O \u2212 , -hydroxy, -straight or branched C 1 -C 6  alkyl or -straight or branched C 1 -C 6  alkoxy; \n each R 4 , R 5 , R 7 , R 8  or R 9  independently is selected from hydrogen, halogen, \u2014OH, \u2014(CH 2 ) x OH, \u2014C\u2261N, \u2014NR a R b , -straight or branched C 1 -C 6  alkyl, -straight or branched-C 1 -C 6  haloalkyl, -straight or branched C 1 -C 6  alkoxy, -straight or branched C 1 -C 6  haloalkoxy, \u2014O-straight or branched-C 1 -C 6  haloalkyl; \n R 6 \u2032 is heterocyclyl, aryl, or heteroaryl; \n wherein:\n each R 4 , R 5 , R 6 , R 7 , R 8  or R 9  as defined above optionally is further substituted with one or more substituents selected from hydrogen, halogen, \u2014OH, \u2014(CH 2 ) x OH, \u2014C\u2261N, \u2014NR c R d , \u2014(CH 2 ) x NR e R f , -straight or branched C 1 -C 6  alkyl, -straight or branched-C 1 -C 6  haloalkyl, -straight or branched C 1 -C 6  alkoxy, \u2014(CH 2 ) x  straight or branched C 1 -C 6  alkoxy, -straight or branched C 1 -C 6  haloalkoxy, \u2014O-straight or branched-C 1 -C 6  haloalkyl, \u2014C 1 -C 6  cycloalkyl, \u2014(CH 2 ) x \u2014 cycloalkyl, -heterocyclyl, \u2014(CH 2 ) x -heterocyclyl, \u2014N-heterocyclyl, \u2014(CH 2 ) x N-heterocyclyl, aryl, -heteroaryl, \u2014(CH 2 ) x -heteroaryl, \u2014O\u2014(CH 2 ) x CH(OH)CH 2 (OH), \u2014C(O)OR f , \u2014(CH 2 ) x \u2014C(O)OR f ; \u2014NR g \u2014NR h R i , \u2014(CH 2 ) x \u2014NR g \u2014NR h R i , \u2014O\u2014(CH 2 ) x \u2014N(R g )\u2014NR h R i ; \n wherein: \n each R a , R b , R c , R d , R e , or R f  as defined above independently is selected from hydrogen, -straight or branched C 1 -C 6  alkyl, -straight or branched C 1 -C 6  alkoxy, \u2014(CH 2 ) x  straight or branched C 1 -C 6  alkoxy, \u2014(CH 2 ) x OH, -straight or branched-C 1 -C 6  haloalkyl, \u2014C 1 -C 6 -cycloalkyl, \u2014(CH 2 ) x C 1 -C 6 -cycloalkyl, heterocyclyl, \u2014(CH 2 ) x heterocyclyl, \u2014N-heterocyclyl, \u2014(CH 2 ) x N-heterocyclyl, aryl, heteroaryl, or \u2014(CH 2 ) x heteroaryl, \u2014(CHR g ) x heteroaryl, \u2014NR g R h , \u2014C(O)OR i , \u2014(CH 2 ) x C(O)OR j ; \n wherein:\n each R g , R h , R i , or R l  is hydrogen, -straight or branched C 1 -C 6  alkyl or -straight or branched-C 1 -C 6  haloalkyl; \n \n \n n is an integer selected from 1 to 3; \n x is 0 or an integer from 1 to 6; or \n a pharmaceutically salt thereof.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 94.0
- Lexical Diversity: 1.10526
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14004105', '14068956', '14154239', '13515607', '14110165']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7831946825455139
- 35 USC 102 Novelty (BERT): 0.5485685306348752
- Combined Prediction Score: 0.7597320673544501
- Mean Citation Score: 356.35282599999994
- Max Citation Score: 394.587
- Similarity Product: 272.4700460822582

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test