PATENT CLAIM ANALYSIS

Application Number: 15778763
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-12
Patent Classification: ["435", "468000"]

Abstract:
The present disclosure relates to method and compositions for generating proteins. In particular, the present disclosure relates to electroporation mediated gene delivery in the generation of recombinant proteins (e.g., drug metabolizing enzyme and transporter vesicles) in mammalian cells.

Claim (Index 1):
A method of generating a vesicle that expresses a membrane bound protein, comprising:\n a) contacting a mammalian cell with a nucleic acid encoding a membrane bound protein selected from the group consisting of: ABCB1, ABCB4, ABCB11, ABCC1, ABCC2, ABCC3, ABCC4, ABCC5, ABCC6, ABCG2, and a homolog thereof; b) electroporating said mammalian cell such that said nucleic acid enters said mammalian cell; and c) isolating vesicles expressing said membrane bound protein of interest.

Metadata:
- Claim Count in Document: 15.0
- Percentile: 93.0
- Lexical Diversity: 1.29412
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11045578', '14744848', '14152979', '10701401', '15675548']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5001475124968274
- 35 USC 102 Novelty (BERT): 0.4909134048241575
- Combined Prediction Score: 0.4992241017295604
- Mean Citation Score: 211.90877000000003
- Max Citation Score: 219.15132000000003
- Similarity Product: 165.85166727476118

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test