PATENT CLAIM ANALYSIS

Application Number: 15906438
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "426000"]

Abstract:
Disclosed herein are methods, processes, compositions, and kits for generating bone graft materials for use at a site of bone defect that utilizes a composition which contains liposomal Wnt polypeptide, such as liposomal Wnt3a polypeptide, liposomal Wnt5a polypeptide, or liposomal Wnt10b polypeptide. Also disclosed herein are methods, processes, compositions, and kits for enhancing mammalian bone marrow cells that utilizes a composition which contains liposomal Wnt polypeptide, such as liposomal Wnt3a polypeptide, liposomal Wnt5a polypeptide, or liposomal Wnt10b polypeptide.

Claim (Index 1):
A method of preparing liposomal Wnt polypeptides, comprising:\n a) incubating Wnt polypeptides harvested from a condition media comprising mammalian cells with a nonionic detergent selected from NP-40, octyl glucoside, octyl thioglucoside, Triton X-100, Triton X-114, Tween 20, and Tween 80; b) purifying the Wnt polypeptides with a column to generate purified Wnt polypeptides; and c) contacting the purified Wnt polypeptides with an aqueous solution of liposomes, thereby generating the liposomal Wnt polypeptides.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 88.0
- Lexical Diversity: 2.2439
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14910616', '15868395', '15063317', '14333220', '14337718']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7447620632750167
- 35 USC 102 Novelty (BERT): 0.6304831165408252
- Combined Prediction Score: 0.7333341686015976
- Mean Citation Score: 459.294376
- Max Citation Score: 665.31616
- Similarity Product: 510.2547586309623

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test