PATENT CLAIM ANALYSIS

Application Number: 15756488
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-09
Patent Classification: ["435", "006120"]

Abstract:
The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine, isolating corresponding mRNA, and analyzing expression patterns in order to diagnose and treat various post-kidney transplant complications. In particular, annexin1 mRNA expression patterns are analyzed through a unique diagnostic formula.

Claim (Index 1):
A method of detecting the presence of a post-kidney transplant complication in a subject comprising detecting the levels of ANXA1 in a urine sample from the subject, wherein ANXA1 is in urinary exosomes and microvesicles, and wherein the detection of an elevated level of at least one marker indicates the presence of post-kidney transplant complication in the subject.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 88.0
- Lexical Diversity: 1.21429
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15526296', '14170132', '13710237', '14931716', '14591542']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5470297051438127
- 35 USC 102 Novelty (BERT): 0.5199352440468947
- Combined Prediction Score: 0.5443202590341208
- Mean Citation Score: 271.914458
- Max Citation Score: 310.04675
- Similarity Product: 226.349545922488

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test