PATENT CLAIM ANALYSIS

Application Number: 16002918
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-01
Patent Classification: ["424", "184100"]

Abstract:
The present application relates to the use of bacterial minicells as targeted delivery agents in vivo and in vitro. Described herein are genetically engineered eubacterial minicells designed to preferentially target and deliver therapeutically relevant agents using a minicell surface coupling molecule capable of binding and displaying antibodies or other Fc-containing targeting moiety fusions and conjugates.

Claim (Index 26):
A method of treating cancer in a subject, comprising administering to a subject suffering from cancer a composition comprising a bacterial minicell, wherein the bacterial minicell comprises:\n (i) an Fc-binding fusion protein displayed on the surface of the bacterial minicell, wherein the Fc-binding fusion protein comprises a) an outer membrane anchoring domain and b) an Fc-binding portion of Protein G or an Fc-binding portion of Protein A; (ii) one or more bioactive molecules; and (iii) one or more Fc-containing targeting molecules bound to the Fc-binding portion of Protein G or Protein A, wherein the one or more Fc-containing targeting molecules recognize a eukaryotic antigen.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 94.0
- Lexical Diversity: 1.1875
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13397313', '15425181', '15044403', '11211098', '14152979']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6619979750560556
- 35 USC 102 Novelty (BERT): 0.5990988053704052
- Combined Prediction Score: 0.6557080580874906
- Mean Citation Score: 365.160398
- Max Citation Score: 559.9877299999998
- Similarity Product: 423.9514155215953

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test