PATENT CLAIM ANALYSIS

Application Number: 16058194
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2020-02
Patent Classification: ["null", "null"]

Abstract:
A method for parallel accumulation and serial fragmentation of ions, wherein ions are injected into a device capable of serial ejection using a pseudopotential barrier created by an RF voltage. In all instances, the ions may be filtered prior to accumulation in the device capable of serial ejection. In some cases this filtering may take the form of discrete isolation windows using isolation waveforms with multiple notches. In some cases these waveforms may be applied to a quadrupole mass filter. Following accumulation of the precursor ions, the initial population may be serially ejected using a pseudopotential barrier created by an RF voltage. Following serial ejection, the individual precursor ion populations are analyzed. In some cases, this analysis might involve additional rounds of ion isolation and manipulation (e.g., MSn, CID, ETD, etc.).

Claim (Index 1):
A method for mass spectrometric analysis of ions of a plurality of ion species generated by ionization of a sample, comprising:\n (a) isolating a plurality of portions of the ions, each portion consisting of a subset of the ion species within a respective range of mass-to-charge (m/z) values; (b) simultaneously retaining the isolated plurality of portions of the ions in an ion storage apparatus, wherein the retaining is at least partially facilitated by applying an auxiliary radio-frequency (RF) voltage waveform to a one of two electrode members of the ion storage apparatus, thereby generating a pseudopotential between the two electrode members, each electrode member either consisting of a single electrode or comprising a group of electrodes; (c) releasing the retained isolated portions of the ion species one at a time from the ion storage apparatus, the releasing comprising one or more of: varying a DC potential applied to a one of the electrode members, varying DC potentials applied to both of the electrode members, or reducing an amplitude of the applied auxiliary RF voltage waveform; and (d) fragmenting or reacting each released portion of the ion species to thereby generate a respective set of product ion species and mass analyzing the product ion species.

Metadata:
- Claim Count in Document: 36.0
- Percentile: 96.0
- Lexical Diversity: 1.89873
- Patent Class: nan
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11409169', '12111484', '11133724', '11394504', '14631959']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5667628986261818
- 35 USC 102 Novelty (BERT): 0.5096144820588239
- Combined Prediction Score: 0.561048056969446
- Mean Citation Score: 300.9517
- Max Citation Score: 308.9958200000001
- Similarity Product: 241.2094155452133

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test