PATENT CLAIM ANALYSIS

Application Number: 15988802
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "370000"]

Abstract:
The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.

Claim (Index 24):
A process of preparing cryopreserved transiently transfected recombinant cells, the process comprising:\n transiently transfecting cells with one or more genes encoding a drug transporter protein to provide the transiently transfected recombinant cells, and cryopreserving the transiently transfected recombinant cells within 48 hours of transient transfection, wherein a population of the transiently transfected recombinant cells transiently overexpress the one or more genes encoding the drug transporter protein at a detectable level prior to cryopreserving the transiently transfected recombinant cells, wherein the transient transfection of the cells comprises electroporation, and wherein said one or more genes is OAT1 and wherein said cell is HEK293.

Metadata:
- Claim Count in Document: 23.0
- Percentile: 93.0
- Lexical Diversity: 1.4359
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15163218', '15688942', '15988819', '15688983', '14972012']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8205999873661137
- 35 USC 102 Novelty (BERT): 0.7676732253170752
- Combined Prediction Score: 0.8153073111612098
- Mean Citation Score: 897.8125239999997
- Max Citation Score: 937.61475
- Similarity Product: 931.2850237689166

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test