PATENT CLAIM ANALYSIS

Application Number: 16279291
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-06
Patent Classification: ["514", "258100"]

Abstract:
Disclosed are a condensed-ring pyrimidylamino derivative, a preparation method therefor, and an intermediate, a pharmaceutical composition and applications thereof. The method for preparing the condensed-ring pyrimidylamino derivative comprises: in a solvent, in the presence of a palladium-containing catalyst, allowing a compound represented by formula I-a and a compound represented by formula I-b′ to have a coupling reaction, and then preparing a compound represented by formula I by means of a deprotection reaction. Also disclosed applications of the condensed-ring pyrimidylamino derivative in the preparation of drugs for preventing, relieving and/or treating tumors or diseases caused by an anaplastic lymphoma kinase. The condensed-ring pyrimidylamino derivative of the present invention has an obvious restraint effect on the anaplastic lymphoma kinase.

Claim (Index 8):
The condensed-ring pyrimidylamino derivative, the tautomer, the mesomer, the racemate, the stereoisomer, the pharmaceutically acceptable salt or the prodrug thereof according to  claim 1 , wherein:\n the R 1  is methyl, methoxy, ethoxy, trifluoromethyl, fluorine, the R 2  is when the ring B is the aromatic ring, the R 3  is methoxy, isopropoxy, methyl, isopropyl, when the ring B is the aromatic ring, the R 3  is and\n the R 4  is methyl or fluorine.

Metadata:
- Claim Count in Document: 44.0
- Percentile: 99.0
- Lexical Diversity: 1.95455
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15568999', '15985848', '15559181', '15746254', '15025618']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7675341598477373
- 35 USC 102 Novelty (BERT): 0.5887070535335285
- Combined Prediction Score: 0.7496514492163164
- Mean Citation Score: 351.83731
- Max Citation Score: 477.65143
- Similarity Product: 438.1171369788134

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test