PATENT CLAIM ANALYSIS

Application Number: 15757005
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["536", "055100"]

Abstract:
The present invention relates to a xylene-based amphiphilic compound, a method for preparing the same, and a method for extracting, solubilizing, stabilizing or crystallizing a membrane protein using the same. By using the xylene-based compound according to the present invention, a membrane protein may be stably stored in an aqueous solution for a long time, and may be applied in functional and structural analyses. The structural and functional analysis of the membrane protein is one of the fields of highest interest in biology and chemistry, and the xylene-based compound according to the present invention can be applied in research on protein structure that is closely related to development of a new drug.

Claim (Index 12):
A method for extracting, solubilizing, stabilizing, crystallizing or analyzing a membrane protein, the method comprising:\n treating a membrane protein with the compound represented by Formula 1 below in an aqueous solution: where the position of A 2 , relative to A 1 , is ortho, meta or para; A 1  and A 2  are the same or different and each independently represented by Formula 2 below; R 1  is a substituted or unsubstituted C 3 -C 26  alkyl group, a substituted or unsubstituted C 3 -C 26  cycloalkyl group, or a substituted or unsubstituted C 3 -C 26  aryl group; X 1  and X 2  are each independently a saccharide linked by an oxygen atom; and the symbol * in Formula 2 may represent a part linked to the core structure of Formula 1.

Metadata:
- Claim Count in Document: 18.0
- Percentile: 90.0
- Lexical Diversity: 2.03333
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16316622', '14931225', '13826466', '13669198', '14337496']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6374895298665247
- 35 USC 102 Novelty (BERT): 0.5503931867320777
- Combined Prediction Score: 0.62877989555308
- Mean Citation Score: 322.59695
- Max Citation Score: 427.55887
- Similarity Product: 364.8369926307834

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test