PATENT CLAIM ANALYSIS

Application Number: 15766821
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-02
Patent Classification: ["424", "135100"]

Abstract:
The present disclosure relates to methods for treating various rare genetic disorders which are characterized, in part, by abnormal resistance to insulin and/or hyperglycemia using a glucagon receptor blocking agent. In various embodiments, the present disclosure relates to methods for treating a rare genetic disorder using antigen binding and antagonizing proteins, e.g., fully human antibodies, that specifically bind to and antagonize the function of the human glucagon receptor.

Claim (Index 24):
A method according to  claim 21 , wherein the isolated antagonistic antigen binding protein comprises an antibody selected from the group consisting of a fully human antibody, a humanized antibody, a chimeric antibody, a monoclonal antibody, a polyclonal antibody, a recombinant antibody, an antigen-binding antibody fragment, a Fab, a Fab\u2032, a Fab 2 , a Fab\u20322, a IgG, a IgM, a IgA, a IgE, a scFv, a dsFv, a dAb, a nanobody, a unibody, a diabody, and a hemibody, wherein the isolated antagonistic binding protein binds to a human glucagon receptor with a dissociation constant (K D ) of at least about 1\u00d710 \u22127  M, at least about 1\u00d710 \u22128  M, at least about 1\u00d710 \u22129  M, at least about 1\u00d710 \u221210  M, at least about 1\u00d710 \u221211  M, or at least about 1\u00d710 \u221212  M.

Metadata:
- Claim Count in Document: 41.0
- Percentile: 91.0
- Lexical Diversity: 1.52
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15316866', '13900275', '14855274', '15415672', '13301944']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8040810762706135
- 35 USC 102 Novelty (BERT): 0.5235922554320134
- Combined Prediction Score: 0.7760321941867536
- Mean Citation Score: 339.65670200000005
- Max Citation Score: 344.82382
- Similarity Product: 260.24460186178686

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test