PATENT CLAIM ANALYSIS

Application Number: 16141595
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["548", "202000"]

Abstract:
Described herein are analogues of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogues having terminal alkyne groups at the 2-position of the thiazole ring. These drug-like molecules, referred to as CETZOLE compounds, are useful to treat non-small cell lung cancer and other forms of cancer. Methods of making and using the compounds, methods of treating various diseases, pharmaceutical compositions, and kits are also disclosed.

Claim (Index 10):
A method of treating cancer comprising administering to a subject an agent that is lethal to cells by a mechanism that does not depend on apoptosis, wherein the agent comprises a compound having a 4-cyclopentyenyl-2-ethynylthiazole skeleton and a terminal alkyne at the 2-position of the thiazole ring.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 97.0
- Lexical Diversity: 1.5
- Patent Class: 548.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15706974', '14762259', '14246558', '14235620', '14436387']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6669753192556983
- 35 USC 102 Novelty (BERT): 0.540126248867167
- Combined Prediction Score: 0.6542904122168451
- Mean Citation Score: 272.32688399999995
- Max Citation Score: 373.2681
- Similarity Product: 270.4789710369766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test