PATENT CLAIM ANALYSIS

Application Number: 16204584
Application Type: Utility
Filing Date: 2018-11
Publication Date: 2019-06
Patent Classification: ["514", "300000"]

Abstract:
The present invention includes novel substituted 2-N-hydroxy-1,3-dioxo-1,2,3,4-tetrahydronaphthyridines, which can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention inhibit HBV RNAse H activity.

Claim (Index 1):
A compound of formula (I): wherein:\n R 1  is selected from the group consisting of \u2014OR\u2032 and \u2014NR\u2032R\u2032, wherein each occurrence of R\u2032 is independently selected from the group consisting of H, optionally substituted C 1 -C 6  alkyl, optionally substituted C 2 -C 6  alkenyl, optionally substituted C 2 -C 6  alkynyl, optionally substituted C 3 -C 8  cycloalkyl, optionally substituted benzyl, optionally substituted aryl, and optionally substituted heteroaryl; \n each of X 1 , X 2 , X 3 , and X 4  is independently selected from the group consisting of N and CR 3 , with the proviso that 1-2 of X 1 , X 2 , X 3 , and X 4  are N; \n R 2  and R 3  are independently selected from the group consisting of H, C 1 -C 6  alkyl, C 1 -C 6  haloalkyl, C 1 -C 6  haloalkoxy, halo, \u2014CN, \u2014OR\u2033, \u2014NR\u2033R\u2033, \u2014N(C 0 -C 6  alkyl)C(\u2550O)R\u2033, \u2014N(C 0 -C 6  alkyl) S(\u2550O) 2 R\u2033, \u2014NO 2 , \u2014S(\u2550O) 2 NR\u2033R\u2033, \u2014OC(\u2550O)R\u2033, and \u2014C(\u2550O)O\u2014C 1 -C 6  alkyl, wherein each occurrence of R\u2033 is independently selected from the group consisting of H, optionally substituted C 1 -C 6  alkyl, optionally substituted C 3 -C 8  cycloalkyl, and optionally substituted phenyl; and \n n is 0, 1, 2, 3, or 4; \n or a salt, solvate, geometric isomer, stereoisomer, tautomer, or any mixtures thereof

Metadata:
- Claim Count in Document: 65.0
- Percentile: 98.0
- Lexical Diversity: 1.12821
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['16204748', '15738734', '14361278', '12747109', '10587682']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7736815254294214
- 35 USC 102 Novelty (BERT): 0.5219025802772261
- Combined Prediction Score: 0.7485036309142018
- Mean Citation Score: 285.7352
- Max Citation Score: 326.30392
- Similarity Product: 290.8482862823868

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test