PATENT CLAIM ANALYSIS

Application Number: 16005349
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2019-04
Patent Classification: ["544", "101000"]

Abstract:
The present invention provides a combination of at least one oxazolidinone-quinolone hybrid with at least one further antibacterial compound and the use thereof as drug, especially for the treatment or prophylaxis of bacterial infections.

Claim (Index 2):
A combination of\n i) at least one oxazolidinone-quinolone hybrid of a compound of formula (I) wherein A is an alkylene group, an alkenylene group, an alkynylene group, a heteroalkylene group, a cycloalkylene group, a heterocycloalkylene group, an alkylcycloalkylene group, a heteroalkylcycloalkylene group, an arylene group or a heteroarylene group all of which groups may be substituted;\n X is CR 7  or N; \n Y is CR 6  or N; \n n is 1, 2 or 3; \n m is 1, 2 or 3; \n R 1  is H, F, Cl, Br, I, OH, NH 2 , an alkyl group or a heteroalkyl group;\n R 2  is H, F or Cl; \n R 3  is H, an alkyl group, an alkenyl group, an alkynyl group, a heteroalkyl group, a cycloalkyl group, a heterocycloalkyl group, an alkylcycloalkyl group, a heteroalkylcycloalkyl group, an aryl group, a heteroaryl group, an aralkyl group or a heteroaralkyl group; all of which groups may be substituted with one, two or more halogen atoms like F or Cl or amino groups; R 4  is hydrogen, a group of formula PO 3 R 9 2  or SO 3 R 10  or a heteroalkyl group carrying at least one OH, NH 2 , SO 3 R 10 , PO 3 R 9 2  or COOH group or an ester of a naturally occurring amino acid or a derivative thereof, wherein the groups R 9  independently of each other are H, alkyl, cycloalkyl, aryl or aralkyl and wherein R 10  is H, alkyl, cycloalkyl, aryl or aralkyl;\n R 5  is selected from following groups: \n R 6  is H, F, Cl or OMe; R 7  is H, F, Cl, OH, NH 2 , a substituted or unsubstituted alkyl group or a substituted or unsubstituted heteroalkyl group, or R 3  and R 7  can be linked via an alkylene, an alkenylene or a heteroalkylene group or be a part of a cycloalkylene or heterocycloalkylene group; in case R 3  is no H and R 7  is no H, F, OH, NH 2  or Cl; and R 8  is a C 1-6  alkyl, a C 1-6  heteroalkyl or a heteroaralkyl group; or a pharmacologically acceptable salt, solvate or hydrate thereof; and ii) at least one further antibacterial compound which is different from compound (i) and selected from the ceftriaxone, ampicillin, fosfomycin, polypeptides, linezolid and moxifloxacin.

Metadata:
- Claim Count in Document: 46.0
- Percentile: 94.0
- Lexical Diversity: 1.16129
- Patent Class: 544.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14894408', '14773603', '13989600', '14110818', '14872988']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.76607838061831
- 35 USC 102 Novelty (BERT): 0.5860829481935357
- Combined Prediction Score: 0.7480788373758326
- Mean Citation Score: 340.4518700000001
- Max Citation Score: 532.22003
- Similarity Product: 389.8269129262197

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test