PATENT CLAIM ANALYSIS

Application Number: 16009527
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-12
Patent Classification: ["514", "350000"]

Abstract:
A pharmaceutically acceptable transdermal composition for the treatment of patients with musculoskeletal connective tissue fibrosis or a disorder including Dupuytren's Contracture, Peyronie's disease, Ledderhose disease, or Knuckle Pads, includes an active composition and a base composition. The active composition is present in the transdermal composition in an amount of about 10% to about 40% by weight of the transdermal composition and includes one or more growth factor antagonists. The base composition is present in an amount of about 60% to about 90% by weight of the transdermal composition and comprises a transdermal delivery system or transdermal carrier. A method of treating patients with musculoskeletal connective tissue fibrosis, including topically applying the transdermal composition in effective amount to the affected tissue is further disclosed. 20

Claim (Index 6):
A transdermal composition for the treatment of patients with a musculoskeletal connective tissue disorder selected from the group consisting of Dupuytren's Contrature, Peyronie's Disease, Ledderhose Disease, and Knuckle Pads, the transdermal composition comprising:\n a) an active composition present in an amount of about 10% to 40% by weight of the transdermal composition, the active composition comprising one or more growth factor antagonists, the antagonists antagonize one or more growth factors selected from the group consisting of Transforming Growth Factor Beta 1 (TGF\u03b21), Platelet-Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF), and Basic Fibroblast Growth Factor (bFGF or FGF2); b) a base composition present in an amount of about 60% to 90% by weight of the transdermal composition, the base composition comprising a transdermal cream.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 94.0
- Lexical Diversity: 2.10606
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14981167', '13747151', '14610875', '15177760', '15831650']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7197323519300236
- 35 USC 102 Novelty (BERT): 0.4951771939163182
- Combined Prediction Score: 0.6972768361286531
- Mean Citation Score: 175.113236
- Max Citation Score: 179.13127
- Similarity Product: 111.968681740731

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test