PATENT CLAIM ANALYSIS

Application Number: 16125341
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-01
Patent Classification: ["514", "449000"]

Abstract:
Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of taxane-based compounds and/or fluorinated forms thereof. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the taxane-based compound is achieved.

Claim (Index 8):
The conjugate of any one of  claims 1  to  7 , wherein the spacer moiety has the structure corresponding to \u2014Y\u2014Z\u2014, where Y is\n \u2014(CR x R y ) a \u2014K w \u2014(CR x R y ) b \u2014(CH 2 CH 2 O) c \u2014(CR x R y ) d \u2014K z \u2014, \n wherein:\n each R x  and R y , in each occurrence, is independently H or an organic radical selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, and substituted aryl, \n (a) is zero or an integer of from 1 to 12; \n (b) is zero or an integer of from 1 to 12; \n (c) is zero or an integer of from 1 to 25; \n (d) is zero or an integer of from 1 to 12; \n K w  is selected from the group consisting of \u2014NH\u2014, \u2014C(O)\u2014, \u2014C(O)NH\u2014, \u2014NH\u2014C(O)\u2014, \u2014O\u2014, \u2014S\u2014, O\u2014C(O)\u2014, C(O)\u2014O\u2014, \u2014O\u2014C(O)\u2014O\u2014, O\u2014C(O)\u2014NH\u2014, \u2014NH\u2014C(O)\u2014O\u2014; and \n K z  is selected from the group consisting of \u2014NH\u2014, \u2014C(O)\u2014, \u2014C(O)NH\u2014, \u2014NH\u2014C(O)\u2014, \u2014O\u2014, \u2014S\u2014, O\u2014C(O)\u2014, C(O)\u2014O\u2014, \u2014O\u2014C(O)\u2014O\u2014, O\u2014C(O)\u2014NH\u2014, \u2014NH\u2014C(O)\u2014O\u2014, and \n Z is selected from \u2014C(O)\u2014O\u2014, O\u2014C(O)\u2014O\u2014, \u2014O\u2014C(O)\u2014NH\u2014 and \u2014NH\u2014C(O)\u2014O\u2014.

Metadata:
- Claim Count in Document: 28.0
- Percentile: 97.0
- Lexical Diversity: 1.35135
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15045077', '13433100', '14223572', '12361427', '15510345']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7288852696861828
- 35 USC 102 Novelty (BERT): 0.5042216672304881
- Combined Prediction Score: 0.7064189094406134
- Mean Citation Score: 232.760714
- Max Citation Score: 252.43303
- Similarity Product: 190.4538078360856

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test