PATENT CLAIM ANALYSIS

Application Number: 15773524
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["424", "234100"]

Abstract:
The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains for use in a method of treating a malignant solid tumor in a subject.

Claim (Index 1):
A recombinant virulence attenuated Gram-negative bacterial strain transformed with a vector which comprises in the 5\u2032 to 3\u2032 direction:\n a promoter; \n a first DNA sequence encoding a delivery signal from a bacterial effector protein, operably linked to said promoter; \n a second DNA sequence encoding a heterologous protein fused in frame to the 3\u2032end of said first DNA sequence, for use in a method of treating a malignant solid tumor in a subject, wherein the recombinant virulence attenuated Gram-negative bacterial strain accumulates in the malignant solid tumor, the method comprising administering to the subject said recombinant virulence attenuated Gram-negative bacterial strain, wherein the recombinant virulence attenuated Gram-negative bacterial strain is administered in an amount that is sufficient to treat the subject.

Metadata:
- Claim Count in Document: 30.0
- Percentile: 93.0
- Lexical Diversity: 1.13043
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15039116', '13364437', '10818071', '15565609', '09763620']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6910208955817704
- 35 USC 102 Novelty (BERT): 0.5220561510562127
- Combined Prediction Score: 0.6741244211292147
- Mean Citation Score: 279.251184
- Max Citation Score: 299.61252
- Similarity Product: 203.2428945328188

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test