PATENT CLAIM ANALYSIS

Application Number: 15870557
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["514", "230500"]

Abstract:
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.

Claim (Index 58):
The compound of  claim 56 , or a pharmaceutically acceptable salt thereof, wherein:\n R 13  is \u2014Y\u2014Z, in which Y is s a bond or \u2014CH 2 \u2014, Z is \u2014SO 2 R b , \u2014N(R a )SO 2 R b  or \u2014SO 2 N(R a ) 2 , each R a  is independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl, and R b  is alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl; R 1  is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl; and R 3  is hydrogen, halogen, alkyl, alkylsulfonyl, alkylsulfinyl, alkoxy, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 86.0
- Lexical Diversity: 1.425
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15130503', '14517705', '15488674', '14658048', '14789881']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8531838789524232
- 35 USC 102 Novelty (BERT): 0.5879234966621856
- Combined Prediction Score: 0.8266578407233995
- Mean Citation Score: 490.161302
- Max Citation Score: 508.7241
- Similarity Product: 444.07260954877137

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test