PATENT CLAIM ANALYSIS

Application Number: 15902301
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["435", "189000"]

Abstract:
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize chiral compounds.

Claim (Index 1):
An engineered ketoreductase polypeptide comprising an amino acid sequence that is at least 90% identical to the reference sequence SEQ ID NO:4, and wherein said amino acid sequence comprises a substitution at position 147.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 88.0
- Lexical Diversity: 1.43243
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15184018', '12197286', '13110789', '15711070', '15211505']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7444251209328077
- 35 USC 102 Novelty (BERT): 0.6463257703110231
- Combined Prediction Score: 0.7346151858706291
- Mean Citation Score: 613.561448
- Max Citation Score: 670.1730299999998
- Similarity Product: 597.8446072072413

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test