PATENT CLAIM ANALYSIS

Application Number: 15890156
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-06
Patent Classification: ["424", "450000"]

Abstract:
Mucus-penetrating liposomal nanoparticles and methods of making and using thereof are described herein. The nanoparticles contain one or more lipids, one or more PEG-conjugated lipids, and optionally one or more additional materials that physically and/or chemically stabilize the particles. The nanoparticle have an average diameter of about 100 nm to about 300 nm, preferably from about 100 nm to about 250 nm, more preferably from about 100 nm to about 200 nm. The particles are mobile in mucus. The liposomes can further contain one or more therapeutic, prophylactic, and/or diagnostic agent to be delivered to a mucosal surface, such as the CV tract, the colon, the nose, the lungs, and/or the eyes. The liposomes can further contain one or more CEST agents to allow real time imaging of the particles in a live animal. The particles may also further contain an imaging agent, such as a fluorescent label.

Claim (Index 6):
The particles of  claim 5 , wherein the PEG-conjugated phospholipid is selected from the group consisting of one or more of the lipids in Table 1.

Metadata:
- Claim Count in Document: 1.0
- Percentile: 88.0
- Lexical Diversity: 2.0875
- Patent Class: 424.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14397828', '14765881', '14765620', '15320903', '14208297']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7429434680076521
- 35 USC 102 Novelty (BERT): 0.5287201410811734
- Combined Prediction Score: 0.7215211353150043
- Mean Citation Score: 241.026338
- Max Citation Score: 358.7201
- Similarity Product: 310.9564397962451

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test