PATENT CLAIM ANALYSIS

Application Number: 15890302
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2019-02
Patent Classification: ["424", "158100"]

Abstract:
The present disclosure relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.

Claim (Index 1):
An isolated antibody or antigen-binding fragment thereof that binds to \u03b2-klotho, wherein the antibody or antigen-binding fragment thereof comprises:\n a heavy chain CDR1 (HCDR1) comprising the amino acid sequence of SEQ ID NO: 6, 9, 10 or 12; a heavy chain CDR2 (HCDR2) comprising the amino acid sequence of SEQ ID NO: 7,11 or 13; a heavy chain CDR3 (HCDR3) comprising the amino acid sequence of SEQ ID NO: 8 or 14; a light chain CDR1 (LCDR1) comprising the amino acid sequence of SEQ ID NO: 19, 31, 22, or 25; a light chain CDR2 (LCDR2) comprising the amino acid sequence of SEQ ID NO: 20 or 23; and a light chain CDR3 (LCDR3) comprising the amino acid sequence of SEQ ID NO: 21 or 24.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 88.0
- Lexical Diversity: 1.12
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14309330', '15759148', '13716526', '14163752', '15604556']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7964658026375695
- 35 USC 102 Novelty (BERT): 0.5701907828359893
- Combined Prediction Score: 0.7738383006574115
- Mean Citation Score: 468.53897
- Max Citation Score: 477.58057
- Similarity Product: 401.0483651841819

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test