PATENT CLAIM ANALYSIS

Application Number: 15950683
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2019-01
Patent Classification: ["514", "221000"]

Abstract:
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.

Claim (Index 63):
A compound, or a pharmaceutically acceptable salt thereof, having the structure of Formula (III): wherein: Z is \u2550N\u2014 or \u2550C(H)\u2014; R 1  is halogen, \u2014OR 5 , \u2014NO 2 , \u2014CN, substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 1 -C 6 fluoroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or \u2014CO 2 R 6 ; each R 2  is independently halogen, \u2014OR 5 , NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, or substituted or unsubstituted C 1 -C 6 fluoroalkyl; R 3  is \u2014X\u2014R 4 ; X is \u2014O\u2014, \u2014S\u2014, \u2014S(O) 2 \u2014, \u2014N(R 7 )\u2014, or \u2014C\u2261C\u2014; R 4  is substituted C 1 -C 6 alkyl, substituted or unsubstituted C 3 -C 6 cycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; each R 5  is independently hydrogen, or substituted or unsubstituted C 1 -C 6 alkyl; R 6  is hydrogen or substituted or unsubstituted C 1 -C 6 alkyl; R 7  is hydrogen or substituted or unsubstituted C 1 -C 6 alkyl; each R 8  is independently halogen or substituted or unsubstituted C 1 -C 6 alkyl; R 9  and R 10  are independently hydrogen or substituted or unsubstituted C 1 -C 6 alkyl; n is 0, 1, 2, or 3; and m is 0, 1, or 2.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 91.0
- Lexical Diversity: 1.22222
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15315363', '15301697', '14916292', '15714013', '15820194']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8082607693094234
- 35 USC 102 Novelty (BERT): 0.5660955627059485
- Combined Prediction Score: 0.7840442486490758
- Mean Citation Score: 379.91734400000007
- Max Citation Score: 459.65045
- Similarity Product: 369.0839839843064

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test