PATENT CLAIM ANALYSIS

Application Number: 16058579
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["205", "777500"]

Abstract:
The present invention relates to a nucleic acid sequencing method that determines the sequence of a template nucleic acid by electrochemical means via the depletion of metal ions as a result of its binding to and/or precipitation with pyrophosphate.

Claim (Index 14):
A method of detecting the formation or depletion of pyrophosphate in a sample comprising the steps of:\n a. providing a sample in which pyrophosphate is formed or depleted; b. providing metal ions in said sample, wherein the metal ions are capable of specifically binding pyrophosphate in solution; c. determining in said sample the potential, current or charge at an electrode a first and at least a second time or continuously; d. correlating the difference in potential, current or charge over time with the formation or depletion of pyrophosphate in the sample by using a potentiometer, wherein the electrode of the potentiometer is selective for the metal ion.

Metadata:
- Claim Count in Document: 17.0
- Percentile: 96.0
- Lexical Diversity: 1.25
- Patent Class: 205.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['16058646', '14237328', '09876374', '10788529', '09876375']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7514393907925754
- 35 USC 102 Novelty (BERT): 0.5149448893616011
- Combined Prediction Score: 0.727789940649478
- Mean Citation Score: 232.55133400000005
- Max Citation Score: 314.94968
- Similarity Product: 211.4225082004261

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test