PATENT CLAIM ANALYSIS

Application Number: 15968241
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2019-01
Patent Classification: ["424", "204100"]

Abstract:
A vaccine vector comprising an attenuated, recombinant ranavirus that has at least one foreign expression element is disclosed. In other contemplated embodiments, a vaccine vector comprising a virus, wherein the virus is engineered to express at least two vaccine antigens is disclosed. In addition, methods of delivering human antigens to a mammal are disclosed that include: providing a non-mammalian virus, engineering a recombinant virus that can express at least one foreign molecule by modifying the non-mammalian virus, and using the recombinant ranavirus to deliver human antigens to a mammal.

Claim (Index 13):
The method of  claim 9 , wherein engineering a recombinant virus comprises:\n generating a recombination cassette, wherein the cassette contains homologous sequences flanking a screenable and selectable reporter gene driven by a promoter, infecting at least one cell with the attenuated non-mammalian virus, transfecting the at least one cell with the recombination cassette to form a combination of the at least one cell and the non-mammalian virus, harvesting a modified combination of the at least one cell and the attenuated non-mammalian virus, and selecting from the modified combination the recombinant virus deleted of the target open reading frame or ORF by serial passaging in cells treated with selection specific components.

Metadata:
- Claim Count in Document: 5.0
- Percentile: 93.0
- Lexical Diversity: 1.90385
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12293001', '11022477', '13983722', '12956949', '12090083']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7419073075604574
- 35 USC 102 Novelty (BERT): 0.4941471650369191
- Combined Prediction Score: 0.7171312933081035
- Mean Citation Score: 221.618114
- Max Citation Score: 227.13087
- Similarity Product: 165.43589638326642

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test