PATENT CLAIM ANALYSIS

Application Number: 15872057
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-06
Patent Classification: ["514", "322000"]

Abstract:
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

Claim (Index 1):
A compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein:\n X 1  is \u2014F, \u2014Cl, \u2014CF 3 , \u2014CN, or CH 3 ; \n X 2  is \u2014H, \u2014F, or \u2014Cl; \n Z 1  is N or CH; \n Z 2  is N or CR 0 ; \n Z 3  is CH or N; \n Y is \u2014C(R 4 R 5 )\u2014[C(R 6 R 7 )] n -Q or \u2014C(R 4 )\u2550C(R 6 )-Q; \n R 0  is-H, \u2014F, or CN; \n R 1 , R 2 , and R 3  are each and independently \u2014CH 3 , \u2014CH 2 F, \u2014CF 3 , \u2014C 2 H 5 , \u2014CH 2 CH 2 F, \u2014CH 2 CF 3 ; or optionally R 2  and R 3 , or R 1 , R 2  and R 3 , together with the carbon atom to which they are attached, form a 3-10 membered carbocyclic ring; \n R 4  and R 5  are each and independently \u2014H; \n R 6  and R 7  are each and independently \u2014H, \u2014OH, \u2014CH 3 , or \u2014CF 3 ; or \n optionally, R 5  and R 7  together with the carbon atoms to which they are attached form a cyclopropane ring; and \n each Q is independently \u2014C(O)OR, \u2014OH, \u2014CH 2 OH, \u2014S(O)R\u2032, \u2014P(O)(OH) 2 , \u2014S(O) 2 R\u2032, \u2014S(O) 2 \u2014NR\u2033R\u2032\u2033, or a 5-membered heterocycle selected from the group consisting of: \n J Q  is \u2014H, \u2014OH or \u2014CH 2 OH; R is \u2014H or C 1-4  alkyl; R\u2032 is \u2014OH, C 1-4  alkyl, or \u2014CH 2 C(O)OH; R\u2033 is \u2014H or \u2014CH 3 ; R\u2032\u2033 is \u2014H, a 3-6 membered carbocyclic ring, or C 1-4  alkyl optionally substituted with one or more substituents selected from the group consisting of halogen, \u2014OR a  and \u2014C(O)OR a ; R a  is \u2014H or C 1-4  alkyl; and n is 0 or 1.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 86.0
- Lexical Diversity: 2.65385
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13918048', '15177546', '14305393', '14099054', '14666567']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8133428177231765
- 35 USC 102 Novelty (BERT): 0.5275846458062996
- Combined Prediction Score: 0.7847670005314888
- Mean Citation Score: 315.9048640000001
- Max Citation Score: 350.91568
- Similarity Product: 275.114434751091

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test