PATENT CLAIM ANALYSIS

Application Number: 16068262
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["514", "275000"]

Abstract:
The disclosure provides compounds of the formula I and the pharmaceutically acceptable salts thereof. The variables, e.g. R 1 , R 2 , R 3 , R 4 , A, B, J, V, W, M, J and Ar are defined herein. The disclosure also provides pharmaceutical compositions comprising a compound or salt of formula I and a pharmaceutically acceptable carrier, methods of inhibiting dihydrofolate reductase (DHFR) in vitro or in vivo with a compound or salt of formula I, and methods of treating a bacterial infections, fungal infections, and protozoal infections with a compound or salt of formula I. A compound or salt of formula I can be the first and only active ingredient used in a pharmaceutical composition or method of this disclosure or may be combined with one or more additional active ingredients that are not compounds or salts of formula I.

Claim (Index 6):
The compound or salt of  claim 1 , wherein A is H and B is methyl.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 95.0
- Lexical Diversity: 2.16
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11345201', '14620997', '12754057', '14336427', '12622753']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7552557346828076
- 35 USC 102 Novelty (BERT): 0.5080617538783636
- Combined Prediction Score: 0.7305363366023633
- Mean Citation Score: 249.46942
- Max Citation Score: 259.62924
- Similarity Product: 197.85653705255984

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test