PATENT CLAIM ANALYSIS

Application Number: 15877635
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["435", "007320"]

Abstract:
The invention provides methods and compositions for detecting and diagnosing sexually transmitted infections using a string of epitopes (SOE) specific for detection of causative microorganisms. The antigenic epitopes may be single epitope sequences, a plurality of epitope sequences joined by repeats of glycine (-GG-) and/or lysine (-KK-) to form a series of epitopes (SOE), or nucleotide sequences encoding one or more SOEs and host cells harboring said SOE nucleotide sequences. SOEs specific for highly immunogenic regions of proteins from  Trichomonas, Treponema  and  Neisseria  species are provided. SOEs to detect the presence of  trichomonas  species comprise regions from  Trichomonas -sptciric aldolase, GAPDH, a-enolase and a-actinin proteins. Pharmaceutical compositions comprising SOEs can also be used as vaccines or to elicit an immune response to specific microorganisms.

Claim (Index 24):
A method of eliciting an immune response to a  Trichomonas vaginalis  microorganism in a subject, comprising the steps of\n preparing a pharmaceutical composition comprising\n at least one SOE, which includes at least a plurality of SEQ ID NO: 2, SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 28, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, SEQ ID NO: 41, SEQ ID NO: 44, SEQ ID NO:79-102, SEQ ID NO:107-119, SEQ ID NO:128-133, and SEQ ID NO:137 wherein each of said epitopes is connected by an amino acid linker, \n and a suitable carrier and adjuvant, and \n administering said pharmaceutical composition to said subject in an amount sufficient to stimulate formation of antibodies to said SOE by the immune system of said subject.

Metadata:
- Claim Count in Document: 34.0
- Percentile: 86.0
- Lexical Diversity: 1.65116
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14774158', '11931488', '10112410', '11479780', '15571734']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5390735653136042
- 35 USC 102 Novelty (BERT): 0.604252777736268
- Combined Prediction Score: 0.5455914865558705
- Mean Citation Score: 291.6901220000001
- Max Citation Score: 564.0744
- Similarity Product: 452.65380843157766

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test