PATENT CLAIM ANALYSIS

Application Number: 16367640
Application Type: Utility
Filing Date: 2019-03
Publication Date: 2019-07
Patent Classification: ["435", "212000"]

Abstract:
The present invention provides engineered tyrosine ammonia-lyase (TAL) polypeptides and compositions thereof. In some embodiments, the engineered TAL polypeptides have been optimized to provide enhanced catalytic activity while reducing sensitivity to proteolysis and increasing tolerance to acidic pH levels. The invention also provides methods for utilization of the compositions comprising the engineered TAL polypeptides for therapeutic and industrial purposes.

Claim (Index 23):
The method of  claim 22 , wherein said symptoms of tyrosinemia or alkaptonuria are ameliorated.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 99.0
- Lexical Diversity: 1.41304
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15432429', '14688126', '14255539', '16176896', '15431491']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7138664289618268
- 35 USC 102 Novelty (BERT): 0.691861869757388
- Combined Prediction Score: 0.7116659730413829
- Mean Citation Score: 636.257156
- Max Citation Score: 1009.6068
- Similarity Product: 692.9617284019232

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test