PATENT CLAIM ANALYSIS

Application Number: 16080428
Application Type: Utility
Filing Date: 2018-08
Publication Date: 2019-02
Patent Classification: ["435", "007100"]

Abstract:
Provided are methods of detecting and quantitatively measuring protein-protein interactions between proteins present on the surface of different cells using a sensitive antibody-based assay. Antibodies specific for each target protein are either directly labeled, or are detected by labeled secondary antibodies. The antibodies are labeled with detectable tags that are releasable when the target proteins are within proximity to each other. Also provided are methods for facilitating diagnosis, prognosis, and treatment of cancer using this assay to detect protein-protein interactions between target proteins of interest. Methods of screening test agents that impact the protein-protein interaction are also provided.

Claim (Index 30):
The method of  claim 4 , wherein the sample is a formalin-fixed paraffin-embedded (FFPE) sample.

Metadata:
- Claim Count in Document: 40.0
- Percentile: 96.0
- Lexical Diversity: 1.58209
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12688798', '15663136', '15767801', '14802170', '15588271']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5863206823382474
- 35 USC 102 Novelty (BERT): 0.5271571781835689
- Combined Prediction Score: 0.5804043319227796
- Mean Citation Score: 283.6257260000001
- Max Citation Score: 293.78473
- Similarity Product: 171.71250360820773

Labels:
- Claim Label 101: 0
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test