PATENT CLAIM ANALYSIS

Application Number: 15949802
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-08
Patent Classification: ["514", "009100"]

Abstract:
Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided.

Claim (Index 35):
The method of  claim 34 , wherein the wound or tissue damage is due to stroke, myocardial infarction, acute transverse myelitis (ATM), idiopathic transverse myelitis (ITM), brachial plexus injury, spinal cord injury, or peripheral nerve injury.

Metadata:
- Claim Count in Document: 4.0
- Percentile: 91.0
- Lexical Diversity: 1.87952
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['12783005', '13669856', '15295833', '15295804', '14593107']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.9067385231423184
- 35 USC 102 Novelty (BERT): 0.5772720485649778
- Combined Prediction Score: 0.8737918756845842
- Mean Citation Score: 760.030852
- Max Citation Score: 803.26776
- Similarity Product: 396.7123543078995

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test