PATENT CLAIM ANALYSIS

Application Number: 15874794
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-08
Patent Classification: ["424", "186100"]

Abstract:
The present invention relates to immunization of hypo-responsive groups of individuals. In particular, the present invention provides methods and compositions for eliciting a potent immune response to hepatitis B virus in individuals in need thereof.

Claim (Index 20):
A method for eliciting an immune response against hepatitis B virus (HBV) in a human subject who is a member of a hypo-responsive population, comprising:\n administering to the human subject a first and a second dose of an immunogenic composition comprising a hepatitis B surface antigen (HBsAg) and an immunostimulatory sequence (ISS) present in the immunogenic composition in amounts effective to elicit a seroprotective immune response comprising an anti-HBsAg concentration of at least 10 mUI/mL in the human subject at two months after only two doses, wherein said ISS is single stranded and consists of the nucleotide sequence of SEQ ID NO:1, and said immunogenic composition comprises from about 10 to about 20 \u03bcg of said HBsAg and from about 1000 to about 3000 \u03bcg of said ISS, and wherein said hypo-responsive population comprises one or more of older adults, obese individuals, smokers, patients with chronic liver disease, and hepatitis C virus (HCV)-infected individuals.

Metadata:
- Claim Count in Document: 29.0
- Percentile: 86.0
- Lexical Diversity: 1.22581
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['13448302', '12472223', '13603278', '13220450', '11991438']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.672078430772033
- 35 USC 102 Novelty (BERT): 0.6159052113418227
- Combined Prediction Score: 0.666461108829012
- Mean Citation Score: 289.939572
- Max Citation Score: 543.893
- Similarity Product: 521.0881392446162

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test