PATENT CLAIM ANALYSIS

Application Number: 15765844
Application Type: Utility
Filing Date: 2018-04
Publication Date: 2018-10
Patent Classification: ["514", "277000"]

Abstract:
The present invention provides a novel medicament for preventing or inhibiting acute kidney injury, the medicament comprising, as an active ingredient, an angiotensin II receptor type 2 agonist or a pharmacologically acceptable salt thereof, and being used for treatment or prevention of acute kidney injury. Also, the present invention provides a novel method for preventing or inhibiting acute kidney injury, the method comprising administering, to a patient, an effective amount of an angiotensin II receptor type 2 agonist or a pharmacologically acceptable salt thereof in combination with an anticancer agent and/or an antitumor agent.

Claim (Index 20):
The medicament according to  claim 1 , wherein the angiotensin II receptor type 2 agonist is a sulfonyl malonamide derivative represented by the following general formula (I): [wherein\n R 12  denotes 2-naphthyl, trans-\u03b2-styryl, phenethyl, 3-phenoxypropyl, or 4-phenylbutyl; \n either of R 13  and R 14  denotes a hydrogen atom, and the other denotes isopropyl, isobutyl, neopentyl, allyl, \u2014CH 2 \u2014R 16  {wherein R 16  denotes optionally substituted C 3-10  cycloalkyl, an optionally substituted heterocycle, or \u2014CO\u2014NR 5 R 6  (wherein R 5  and R 6  may be the same or different and each represent a hydrogen atom, C 1-6  alkyl, optionally substituted aryl, or optionally substituted heteroaryl, or R 5  and R 6  may form, together with the nitrogen atom to which they are bonded, optionally substituted cyclic amino)}, \u2014(CH 2 ) 2 \u2014R 16\u2032  (wherein R 16\u2032  denotes cyano or C 1-6  alkoxy), or \u2014(CH 2 ) n \u2014Ar 2  (wherein n denotes an integer of 1 to 3, and Ar 2  denotes substituted phenyl or optionally substituted heteroaryl), or R 13  and R 14  may form, together with the carbon atom to which they are bonded, a moiety represented by the following formula: \n and\n R 15  denotes di(C 1-6  alkyl)amino or a moiety represented by the following formula: \n (wherein Z denotes a hydrogen atom, a halogen atom, or trifluoromethyl, Y denotes a nitrogen atom or CH, and R 17  denotes ethyl, isopropyl, or 3-pentyl, with the proviso that when Y is a nitrogen atom, Z denotes a hydrogen atom)], or a pharmacologically acceptable salt thereof.

Metadata:
- Claim Count in Document: 37.0
- Percentile: 91.0
- Lexical Diversity: 2.0
- Patent Class: 514.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15301438', '12665537', '13234514', '14433149', '09974004']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7778478271866776
- 35 USC 102 Novelty (BERT): 0.6096688485523449
- Combined Prediction Score: 0.7610299293232443
- Mean Citation Score: 317.665034
- Max Citation Score: 590.0824
- Similarity Product: 465.71674044413567

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test