PATENT CLAIM ANALYSIS

Application Number: 16265286
Application Type: Utility
Filing Date: 2019-02
Publication Date: 2019-05
Patent Classification: ["546", "026000"]

Abstract:
The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.

Claim (Index 32):
A process for a chemical synthesis of a compound having the structure of Formula (I): or a salt thereof, wherein:\n R a  is hydrogen or a substituent; \n each n is an integer independently selected from 0, 1, 2, 3, and 4; \n each r is an integer ranging from 0 to (2n+4); and \n each R is an independently selected substituent, wherein two or more neighboring R groups may optionally form a hydrocarbon or heterocyclic ring system; \n the process comprising reacting one or more compounds of Formula II: \n with an N-aminoimide reagent under reaction conditions sufficient to produce the compound of Formula (I) with a yield of at least 75%, wherein R, r and n have the same meaning as described with respect to Formula (I) and Z is O, S, or Me, wherein R f  is hydrogen or a substituent.

Metadata:
- Claim Count in Document: 53.0
- Percentile: 99.0
- Lexical Diversity: 1.14815
- Patent Class: 546.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15558808', '14131973', '14234382', '15566872', '12437711']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7529695599032462
- 35 USC 102 Novelty (BERT): 0.52135362954724
- Combined Prediction Score: 0.7298079668676456
- Mean Citation Score: 221.041246
- Max Citation Score: 336.569
- Similarity Product: 248.5201163038612

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test