PATENT CLAIM ANALYSIS

Application Number: 16125233
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-02
Patent Classification: ["424", "465000"]

Abstract:
The invention relates to small pellets comprising cholestyramine. The pellets have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such pellets. The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.

Claim (Index 22):
The method according to  claim 21 , wherein the bile acid malabsorption is the result of ileal disease (Crohn's disease), ileal resection or ileal bypass, the result of overproduction of bile acids or defective feedback inhibition of hepatic bile acid synthesis, or the result of cholecystectomy, vagotomy, small intestinal bacterial overgrowth (SIBO), coeliac disease, pancreatic insufficiency (chronic pancreatitis, cystic fibrosis), pancreatic transplant, radiation enteritis, collagenous colitis, microscopic colitis, lymphocytic colitis, ulcerative colitis or irritable bowel syndrome (IBS-D).

Metadata:
- Claim Count in Document: 46.0
- Percentile: 97.0
- Lexical Diversity: 1.88462
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['15449781', '15988281', '15449645', '15988560', '11085671']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.750560378264581
- 35 USC 102 Novelty (BERT): 0.5381228365646205
- Combined Prediction Score: 0.729316624094585
- Mean Citation Score: 357.080098
- Max Citation Score: 442.55975
- Similarity Product: 340.3776411267519

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test