PATENT CLAIM ANALYSIS

Application Number: 16074017
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-03
Patent Classification: ["540", "474000"]

Abstract:
A Rapafucin library containing compounds of the general structure, (A) and (E), and a synthesis of these compounds are provided.

Claim (Index 6):
The compound of  claim 5 , wherein the effector domain of formula II has formula VII Wherein R 12 , R 14 , R 14\u2032 , and R 16  are each independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted perfluoroalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted alkylamino, substituted or unsubstituted aryl, substituted or unsubstituted alkylaryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroalkylaryl, (CH 2 ) n CN, (CH 2 ) n CF 3 , (CH 2 ) n C 2 F 5 . R 13 , R 15 , R 15\u2032  and R 17  are each independently the sidechains of naturally occurring amino acids and their modified forms including but are not limited to D-amino acid configuration, or hydrogen, halogen, amino, cyano, nitro, trifluoromethyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted perfluoroalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted alkylamino, substituted or unsubstituted alkylthio, substituted or unsubstituted aryl, substituted or unsubstituted alkylaryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroalkylaryl, substituted or unsubstituted (CH 2 ) n -aryl, substituted or unsubstituted (CH 2 ) n -heteroaryl, (CH 2 ) n CN, (CH 2 ) n CF 3 , (CH 2 ) n C 2 F 5 , (CH 2 ) n OR 19 , (CH 2 ) n C(O)R 19 , (CH 2 ) n C(O)OR 19 , (CH 2 ) n OC(O)R 19 , (CH 2 ) n NR 20 R 21 , (CH 2 ) n C(O)NR 20 R 21 , (CH 2 ) n NR 22 C(O)R 19 , (CH 2 ) n NR 22 C(O)OR 19 , (CH 2 ) n NR 22 C(O)NR 20 R 21 , (CH 2 ) n SR 19 , (CH 2 ) n S(O) j NR 20 R 21 , (CH 2 ) n NR 22 S(O) j R 19 , or \u2014(CH 2 ) n NR 22 S(O) j NR 20 R 21 . R 12  and R 13 , R 14  and R 15 , R 14\u2032  and R 15\u2032 , R 16  and R 17  can be covalently connected to form a substituted or unsubstittued 5-, 6-, or 7-membered heterocycle.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 95.0
- Lexical Diversity: 1.35
- Patent Class: 540.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15728282', '13990396', '14987653', '14793296', '15581749']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6477697587115204
- 35 USC 102 Novelty (BERT): 0.5119859217699936
- Combined Prediction Score: 0.6341913750173678
- Mean Citation Score: 213.20821
- Max Citation Score: 239.5702
- Similarity Product: 165.84298821048736

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test