PATENT CLAIM ANALYSIS

Application Number: 16136414
Application Type: Utility
Filing Date: 2018-09
Publication Date: 2019-11
Patent Classification: ["435", "039000"]

Abstract:
A vacuum ampoule detection system and a method detect and quantify viable bacteria in liquid samples. The vacuum ampoule that includes a supporting medium, a selective reagent, and a detecting reagent are useful in the rapid detection and quantification of viable heterotrophic bacteria in liquid samples. The vacuum ampoule detection system is suitable for the detection of total bacteria,  E. coli,  or total coliform, etc. The vacuum ampoule detection system is also compatible with spectrometer for visible light, UV light and fluorescence which can give more accurate analysis of the concentration of bacteria in the liquid samples.

Claim (Index 6):
A method to quantify viable bacteria in a liquid sample, the method comprising:\n self-filling the liquid sample into a vacuum ampoule containing a supporting medium, at least one selective reagent, and a detection reagent, wherein the detection reagent comprises 2,3,5-triphenyltetrazolium chloride (TTC), and detects viable total bacteria in the liquid sample; mixing the liquid sample with the supporting medium, the at least one selective reagent, and the detection reagent in the self-filled vacuum ampoule; incubating the self-filled vacuum ampoule at about 37\u00b0 C.; during the incubating, observing a change of color of the self-filled vacuum ampoule, wherein the self-filled vacuum ampoule is configured to change color when the viable bacteria are present and react with the detection reagent; measuring an elapsed time from the beginning of incubation to time at the change of color of the self-filled vacuum ampoule; observing the changed color of the self-filled vacuum ampoule; comparing the changed color of the self-filled vacuum ampoule with color gradient references; and determining a viable cell density of the bacteria in the liquid sample based on a predetermined negatively proportional correlation between the elapsed time and the viable cell density of the bacteria, and further based on the comparison of the changed color with the color gradient references.

Metadata:
- Claim Count in Document: 20.0
- Percentile: 97.0
- Lexical Diversity: 1.91071
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11686732', '11376516', '12582392', '13807558', '12767946']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.536670536556119
- 35 USC 102 Novelty (BERT): 0.4798077888437069
- Combined Prediction Score: 0.5309842617848778
- Mean Citation Score: 169.23156200000005
- Max Citation Score: 175.37091
- Similarity Product: 129.29999609176394

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test