PATENT CLAIM ANALYSIS

Application Number: 15873661
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-05
Patent Classification: ["250", "282000"]

Abstract:
The present disclosure provides methods and systems for improved detection and/or quantification of selenium (Se) and/or silicon (Si) in samples. In certain embodiment, the methods and systems feature the use of carbon dioxide (CO 2 ) as a reaction gas in a reaction cell chamber, such as a dynamic reaction cell (DRC), of an inductively coupled plasma mass spectrometer (ICP-MS). It is found that the use of CO 2  as a reaction gas effectively eliminates (or substantially reduces) interfering ionic species for the analytes Se and Si, particularly in samples with complex matrices, and/or in samples with low levels of analyte, thereby enabling more accurate detection of analyte at lower detection limits and in samples having complex matrices.

Claim (Index 1):
A method for producing a stream of ions for detection and/or quantification of selenium (Se) in a sample, the method comprising:\n introducing a sample to an ionization source, thereby producing an ionized sample stream comprising a plurality of ionic species, said plurality of ionic species comprising:\n (i) one or more analyte ionic species, said one or more analyte ionic species being an ionized form of one or more species of interest present in the sample, said one or more species of interest comprising selenium, and said one or more analyte ionic species comprising Se + ; and \n (ii) one or more interferer ionic species, said one or more interferer ionic species having nominal m/z substantially equivalent to that of Se + ; \n admitting the ionized sample stream into a chamber to thereby contact the ionized sample stream with a reaction gas stream comprising CO 2 , thereby reacting the CO 2  with at least one of the one or more interferer ionic species and producing one or more products that are not interferer ionic species; and following contact of the ionized sample stream with the reaction gas stream comprising CO 2 , directing the resulting product stream to a mass analyzer and detector for detection and/or quantification of selenium in the sample.

Metadata:
- Claim Count in Document: 32.0
- Percentile: 86.0
- Lexical Diversity: 1.79221
- Patent Class: 250.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14622132', '12623846', '13948423', '14887320', '10198099']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6553109521863727
- 35 USC 102 Novelty (BERT): 0.485408520426878
- Combined Prediction Score: 0.6383207090104233
- Mean Citation Score: 184.678744
- Max Citation Score: 209.43591
- Similarity Product: 161.53388899499416

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test