PATENT CLAIM ANALYSIS

Application Number: 15774655
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-10
Patent Classification: ["514", "210000"]

Abstract:
In its many embodiments, the present invention provides certain substituted bispiperidinyl compounds of the Formula (I): and pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 3 , L, R 4 , Q and R 5  are as defined herein. The novel compounds of the invention, and pharmaceutically acceptable compositions comprising a compound thereof, are useful as Liver X-β receptor (LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory diseases and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.

Claim (Index 7):
The compound according to  claim 1 , or a pharmaceutically acceptable salt thereof, wherein:\n L is \u2014C(O)\u2014; and R 3  is \u2014N(R N1 )(R N2 ), wherein: R N1  and R N2  are taken together with the nitrogen atom to which they are shown attached to form a 4-, 5-, or 6-membered fully saturated heterocyclic ring comprising (including said nitrogen atom) 1, 2, or 3 ring heteroatoms selected from the group consisting of N, N-oxide, O, S, and S-oxide,\n wherein said heterocyclic ring is unsubstituted or substituted with 1, 2, or 3 substituents independently selected from the group consisting of halogen \u2014OH, oxo, CN, \u2014(C 1 -C 6 )alkyl, amino-substituted \u2014(C 1 -C 6 )alkyl (wherein said amino is 1, 2, or 3 groups independently selected from the group consisting of \u2014NH 2 , \u2014N(C 1 -C 4 alkyl) 2 , and \u2014NH(C 1 -C 4 alkyl)), \u2014O\u2014(C 1 -C 6 )alkyl, \u2014(C 1 -C 6 )alkyl-OH, \u2014(C 1 -C 6 )haloalkyl, \u2014C(O)O\u2014(C 1 -C 6 )alkyl, cyclopropyl, spirocyclopropyl, \u2014CH 2 \u2014NHC(O)O\u2014(C 1 -C 6 )alkyl, \u2014CH 2 \u2014N(CH 3 )C(O)O\u2014(C 1 -C 6 )alkyl, phenyl, benzyl, \u2014NHC(O)-phenyl, heteroaryl, and \u2014(C 1 -C 4 )alkylheteroaryl, heterocycloalkyl.

Metadata:
- Claim Count in Document: 14.0
- Percentile: 93.0
- Lexical Diversity: 1.51282
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15774157', '14721262', '15204422', '14657179', '15182749']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7856884660468791
- 35 USC 102 Novelty (BERT): 0.5545539702683244
- Combined Prediction Score: 0.7625750164690237
- Mean Citation Score: 340.497268
- Max Citation Score: 447.61417
- Similarity Product: 316.6738368749392

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test