PATENT CLAIM ANALYSIS

Application Number: 16228362
Application Type: Utility
Filing Date: 2018-12
Publication Date: 2019-06
Patent Classification: ["506", "016000"]

Abstract:
This disclosure provides methods for preparing a sequencing library including the steps of providing a template nucleic acid sequence, dNTPs, dUTP, a primer, a polymerase, a dUTP excising enzyme, and a plurality of beads including oligonucleotide adapter sequence segments; amplifying the template nucleic acid with the polymerase, dNTPs, dUTP and random hexamer to provide a complementary nucleic acid sequence including occasional dUTPs; and excising the incorporated dUTPs with the dUTP excising enzyme to provide nicks in the complementary nucleic acid sequence to provide a sequencing library.

Claim (Index 38):
The method of  claim 31 , wherein (b) comprises excising said at least one uracil to yield one or more initiation sites corresponding to said one or more sites, and performing one or more extension reactions from said one or more initiation sites to generate said plurality of single-stranded nucleic acid molecules.

Metadata:
- Claim Count in Document: 83.0
- Percentile: 98.0
- Lexical Diversity: 2.15556
- Patent Class: 506.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['14990276', '14316447', '15887947', '16052486', '15842687']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6156736647238344
- 35 USC 102 Novelty (BERT): 0.6156461058860757
- Combined Prediction Score: 0.6156709088400585
- Mean Citation Score: 451.000152
- Max Citation Score: 659.76764
- Similarity Product: 460.39732938218833

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test