PATENT CLAIM ANALYSIS

Application Number: 15772699
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-08
Patent Classification: ["514", "254000"]

Abstract:
Provided are ARTS mimetic compounds that act as novel antagonists for XIAP and Bcl-2. Further, the novel ARTS mimetic compounds of the presently claimed subject matter induce apoptosis and/or differentiation in premalignant and malignant cells and thereby restore their normal-like phenotype. Further provided are compositions, methods and uses of said ARTS mimetic compounds in the treatment of cancer and premalignant conditions.

Claim (Index 57):
The method according to  claim 56 , wherein said ARTS mimetic compound of the general formula (I) is at least one of:\n (a) wherein R 1  is H; (b) wherein R 2  is \u2014C(\u2550O)\u2014X\u2014R 3 ; (c) wherein X is O; (d) wherein L1 and L2 independently selected independently from each other from \u2014NH\u2014C(\u2550O)\u2014(CH 2 ) n \u2014, \u2014(CH 2 ) n \u2014; (e) wherein R 7  is selected from the group consisting of C 5 -C 12  saturated cycloalkyl or C 5 -C 12  heterocycloalkyl; (f) wherein R 8  is optionally substituted straight or branched C 1 -C 12  alkyl, optionally substituted C 5 -C 12  aromatic or optionally substituted heteroaromatic ring; and (g) wherein R 6  is independently selected from the group consisting of H, halogen, CN, NO 2 .

Metadata:
- Claim Count in Document: 20.0
- Percentile: 93.0
- Lexical Diversity: 1.5
- Patent Class: 514.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['11632079', '12270374', '11800220', '10586271', '14386747']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8036095772643069
- 35 USC 102 Novelty (BERT): 0.5264500515884324
- Combined Prediction Score: 0.7758936246967194
- Mean Citation Score: 296.802926
- Max Citation Score: 340.8475
- Similarity Product: 225.93052918821576

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 0
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test