PATENT CLAIM ANALYSIS

Application Number: 15940051
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["424", "133100"]

Abstract:
The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for treating or preventing complement-associated disorders such as, but not limited to, atypical hemolytic uremic syndrome, age-related macular degeneration, rheumatoid arthritis, sepsis, severe burn, antiphospho lipid syndrome, asthma, lupus nephritis, Goodpasture's syndrome, and chronic obstructive pulmonary disease.

Claim (Index 30):
The isolated antibody, or antigen-binding fragment thereof, of  claim 21 , wherein the antibody, or antigen-binding fragment thereof, binds to a free C5a polypeptide, wherein the free C5a is a human polypeptide (hC5a) having the amino acid sequence depicted in SEQ ID NO: 1, and wherein the antibody, or antigen-binding fragment thereof, binds to the free hC5a polypeptide in vitro with a K D  that is less than 1.25\u00d710 \u22129  M in the presence of a molar excess of uncleaved, native human C5.

Metadata:
- Claim Count in Document: 50.0
- Percentile: 90.0
- Lexical Diversity: 1.39286
- Patent Class: 424.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15040258', '15088421', '13695277', '14657176', '15161893']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8696829728264391
- 35 USC 102 Novelty (BERT): 0.7019320311199606
- Combined Prediction Score: 0.8529078786557913
- Mean Citation Score: 778.522778
- Max Citation Score: 803.0433
- Similarity Product: 726.4969364201904

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test