PATENT CLAIM ANALYSIS

Application Number: 16044413
Application Type: Utility
Filing Date: 2018-07
Publication Date: 2019-01
Patent Classification: ["435", "070100"]

Abstract:
Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.

Claim (Index 93):
A method for organizing a first plurality of cells and a second plurality of cells in a specific orientation for the production of one or more immunological proteins, comprising:\n (a) providing a media chamber comprising a first medium, wherein said first medium comprises said first plurality of cells and a first polymeric precursor; (b) directing at least one energy beam to said first medium in said media chamber along at least one energy beam path in accordance with computer instructions for printing a three-dimensional (3D) lymphoid organoid in computer memory, to subject at least a portion of said first medium in said media chamber to form a first portion of said 3D lymphoid organoid; (c) providing a second medium in said media chamber, wherein said second medium comprises said second plurality of cells and a second polymeric precursor, wherein said second plurality of cells is of a different type than said first plurality of cells; (d) directing at least one energy beam to said second medium in said media chamber along at least one energy beam path in accordance with said computer instructions, to subject at least a portion of said second medium in said media chamber to form a second portion of said 3D lymphoid organoid; and (e) subjecting said first and second portions of said 3D lymphoid organoid to conditions sufficient to stimulate production of said one or more immunological proteins.

Metadata:
- Claim Count in Document: 27.0
- Percentile: 95.0
- Lexical Diversity: 1.78571
- Patent Class: 435.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15253078', '13608579', '11116234', '12725698', '13377285']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5845323242228538
- 35 USC 102 Novelty (BERT): 0.4999780650195529
- Combined Prediction Score: 0.5760768983025237
- Mean Citation Score: 214.55778
- Max Citation Score: 222.7462
- Similarity Product: 152.01143070867062

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test