PATENT CLAIM ANALYSIS

Application Number: 16340795
Application Type: Utility
Filing Date: 2019-04
Publication Date: 2019-09
Patent Classification: ["546", "112000"]

Abstract:
The present invention relates to pesticidal and parasiticidal isoxazoline of formula (I) and salts thereof: wherein variables B 1 , B 2 , B 3 , R 1 , P 1 , P 2 , Y and Q are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.

Claim (Index 1):
A pesticidal isoxazoline compound of formula (I): wherein: the asterisk (*) signifies a chiral quaternary center; the squiggly bond ( ) signifies that the double bond may be in the cis- or trans-configuration with respect to P 1  and P 2 ; B 1 , B 2  and B 3  are each independently C\u2014R or N; each R is independently H, halogen, cyano, \u2014NO 2 , alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, \u2014SF 5 , \u2014C(\u2550S)\u2014NH 2 , alkylamino, dialkylamino or alkoxycarbonyl; R 1  is C 1 -C 3 alkyl or C 1 -C 3 haloalkyl; P 1  and P 2  are independently hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl or haloalkylsulfonyl; Y is an optionally substituted phenylene, naphthylene, indanylene, a 5- or 6-membered heteroarylene or an 8-10-membered fused heterobicyclylene, wherein the optional substituents are selected from the group consisting of halogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkylamino, dialkylamino, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, \u2014SF 5 , \u2014CN or \u2014NO 2  and \u2014C(\u2550S)\u2014NH 2 ; Q is X\u2014NR 2 R 3 , the group (\u2014CH 2 \u2014)(\u2014CH 2 \u2014)N\u2014R 3 , OH, NH 2 , alkoxy, haloalkoxy, alkylamino, haloalkylamino, dialkylamino, dihaloalkylamino, thiol, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, \u2014SF 5 , \u2014C(\u2550S)\u2014NH 2 , or an optionally substituted 5- or 6-membered carbocyclyl, heterocyclyl, heteroaryl ring, wherein the optional substituents of said carbocyclyl, heterocyclyl or heteroaryl ring are selected from halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkylamino, dialkylamino, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, \u2014SF 5 , \u2014CN or \u2014NO 2  and \u2014C(\u2550S)\u2014NH 2 ; or the groups T1 or T2: W is O or S; X is (CH 2 ) n , CH(CH 3 ), CH(CN), C(\u2550O) or C(\u2550S); R 2  is H, alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcarbonyl or alkoxycarbonyl; R 3  is H, OR 7 , NR 8 R 9  or Q 1 ; or alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl, each optionally substituted with one or more substituents independently selected from R 4 ; or when Q is X\u2014NR 2 R 3 , R 2  and R 3  taken together with the nitrogen to which they are attached to form a ring containing 2 to 6 atoms of carbon and optionally one additional atom selected from the group consisting of N, S and O, said ring optionally substituted with 1 to 4 substituents independently selected from the group consisting of alkyl, halogen, \u2014CN, \u2014NO 2  and alkoxy; each R 4  is independently halogen; alkyl, cycloalkyl, alkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkylamino, haloalkylamino, dialkylamino, dihaloalkylamino, cycloalkylamino, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, haloalkylcarbonyl, haloalkoxycarbonyl, haloalkylaminocarbonyl, dihaloalkylaminocarbonyl, hydroxy, \u2014SF 5 , \u2014C(\u2550S)NH 2 , \u2014NH 2 , \u2014CN or \u2014NO 2 ; or Q 2 ; each R 5  is independently halogen, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkylamino, dialkylamino, alkoxycarbonyl, \u2014SF 5 , \u2014C(\u2550S)NH 2 , \u2014CN or \u2014NO 2 ; each R 6  is independently halogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkylamino, dialkylamino, \u2014SF 5 , \u2014C(\u2550S)NH 2 , \u2014CN, \u2014NO 2 , phenyl or pyridinyl; R 7  is H; or alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl or cycloalkylalkyl, each optionally substituted with one or more halogens; R 8  is H, alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcarbonyl or alkoxycarbonyl; R 9  is H; Q 3 ; or alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl or cycloalkylalkyl, each optionally substituted with one or more substituents independently selected from R 4 ; or R 8  and R 9  taken together with the nitrogen to which they are attached form a ring containing 2 to 6 atoms of carbon and optionally one additional atom selected from the group consisting of N, S and O, said ring optionally substituted with 1 to 4 substituents independently selected from the group consisting of alkyl, halogen, \u2014CN, \u2014NO 2  and alkoxy; Q 1  is a phenyl ring, a 5- or 6-membered heterocyclic ring, or an 8-, 9- or 10-membered fused bicyclic ring system optionally containing one to three heteroatoms selected from up to 1 O, up to 1 S and up to 3 N, each ring or ring system optionally substituted with one or more substituents independently selected from R 5 ; Q 2  is independently a phenyl ring or a 5- or 6-membered heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from R 6 ; Q 3  is a phenyl ring or a 5- or 6-membered heterocyclic ring, each ring optionally substituted with one or more substituents independently selected from R 6 ; and n is 0, 1 or 2.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 100.0
- Lexical Diversity: 1.68519
- Patent Class: 546.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['14086712', '14658668', '14148410', '15191163', '12970670']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8487099072964086
- 35 USC 102 Novelty (BERT): 0.5334842977709757
- Combined Prediction Score: 0.8171873463438653
- Mean Citation Score: 381.187528
- Max Citation Score: 387.5289
- Similarity Product: 295.30352190899856

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 0

Dataset: test