PATENT CLAIM ANALYSIS

Application Number: 15980454
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-09
Patent Classification: ["435", "007100"]

Abstract:
Methods for improving the specificity of assays for botulinum neurotoxins are described. Reporting constructs are provided that include cleavable linker sequence with genetically modified recognition and/or cleavage sites. These linker sequences act as a substrate for a botulinum neurotoxin, with cleavage of the reporting construct providing a detectable signal. When first and second neurotoxins have activity with the same substrate protein, mutation and/or deletion of a recognition and/or cleavage site associated with the second neurotoxin improves the specificity of the detectable signal for the first neurotoxin.

Claim (Index 19):
The method of one of  claims 15  to  18 , wherein the first neurotoxin is a botulinum neurotoxin.

Metadata:
- Claim Count in Document: 24.0
- Percentile: 93.0
- Lexical Diversity: 1.73585
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['15620062', '13403603', '14631379', '15064379', '13625723']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8064250955159351
- 35 USC 102 Novelty (BERT): 0.5880657182384829
- Combined Prediction Score: 0.7845891577881899
- Mean Citation Score: 689.6785940000003
- Max Citation Score: 706.0129
- Similarity Product: 416.7221892420888

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 0

Dataset: test