PATENT CLAIM ANALYSIS

Application Number: 15742702
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2018-07
Patent Classification: ["435", "006140"]

Abstract:
The use of PHGDH as a biomarker for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject, and the use of PHGDH modulators to treat cancer is disclosed herein. Also disclosed are various methods for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject by measuring PHGDH expression and/or activity.

Claim (Index 39):
A method according to any one of  claims 32  to  38  in which the subject is also contacted with another cancer therapeutic, such as an EMT inhibitor or an Axl inhibitor.

Metadata:
- Claim Count in Document: 71.0
- Percentile: 86.0
- Lexical Diversity: 1.59459
- Patent Class: 435.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: True
- Related Applications: ['14398572', '12742546', '14690001', '13320060', '15533049']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6322305480451059
- 35 USC 102 Novelty (BERT): 0.5234039146246263
- Combined Prediction Score: 0.6213478847030579
- Mean Citation Score: 257.888148
- Max Citation Score: 317.90555
- Similarity Product: 187.66043054804803

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test