PATENT CLAIM ANALYSIS

Application Number: 16162335
Application Type: Utility
Filing Date: 2018-10
Publication Date: 2019-04
Patent Classification: ["424", "422000"]

Abstract:
Disclosed herein are methods and pharmaceutical compositions for sustained release of anticancer agents. Such pharmaceutical compositions may provide a burst-free, sustained release of one or more anticancer agents and may include a plurality of poly(lactic-co-glycolic) acid (PLGA) microparticles encapsulating the one or more anticancer agents.

Claim (Index 66):
A pharmaceutical composition comprising microparticles having a polydisperse particle size distribution,\n wherein the microparticles have a mean particle size diameter from about 20 micrometers to about 40 micrometers with a standard deviation of about 20 micrometers; wherein the microparticles are comprised of are comprised of polymer units selected from the group consisting of polylactic acid (PLA), polyglycolic acid (PGA), poly(lactic-co-glycolic) acid (PLGA), polybutylene succinate (PBS), polyhydroxyalkanoate (PHA), polycaprolactone acid lactone (PCL), polyhydroxybutyrate (PHB), glycolic amyl acid (PHV), PHB and PHV copolymer (PHBV), and PLA-polyethylene glycol (PEG) copolymer (PLEG); wherein a first population of the microparticles is comprised of polymer units having a molecular weight of about 5 kDa to about 33 kDa; wherein a second population of the microparticles is comprised of polymer units having a molecular weight of about 42 kDa to about 150 kDa; and wherein the microparticles encapsulate an anticancer agent.

Metadata:
- Claim Count in Document: 56.0
- Percentile: 97.0
- Lexical Diversity: 1.55882
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12664792', '11607382', '13422994', '14461884', '15349985']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7325778324872563
- 35 USC 102 Novelty (BERT): 0.5024700767170193
- Combined Prediction Score: 0.7095670569102326
- Mean Citation Score: 239.511742
- Max Citation Score: 251.67445
- Similarity Product: 172.4363613853246

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test