PATENT CLAIM ANALYSIS

Application Number: 15899716
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-10
Patent Classification: ["435", "325000"]

Abstract:
The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErhB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying au ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.

Claim (Index 26):
The method of  claim 16 , wherein the cancer is selected from the group consisting of breast cancer, ovarian cancer, gastric cancer, prostate cancer, squamous cell carcinoma, head and neck cancer, colon cancer, pancreatic cancer, uterine cancer, renal cell cancer, glioblastoma, medulloblastoma, sarcoma, and lung cancer.

Metadata:
- Claim Count in Document: 2.0
- Percentile: 88.0
- Lexical Diversity: 2.41379
- Patent Class: 435.0
- Transitional Phrase Type: closed
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['15319660', '13821491', '15726943', '14928794', '15269731']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6662640277665053
- 35 USC 102 Novelty (BERT): 0.6149330144608413
- Combined Prediction Score: 0.6611309264359388
- Mean Citation Score: 423.66853
- Max Citation Score: 786.81683
- Similarity Product: 472.6253629216367

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test