PATENT CLAIM ANALYSIS

Application Number: 15915909
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["536", "025400"]

Abstract:
Ligands and methods for selectively binding hypermethylated DNA from a sample. The ligands include a CG-region binding molecule-conjugated resin derived from the aminoglycoside antibiotic amikacin. Furthermore, the CG-region binding molecule may be conjugated to the resin with a crosslinker and/or may be modified with one or more of long chain and short chain alkyl, aryl, piperazinyl, piperidyl, and pyrrolidyl groups. Such ligands are used in methods for contacting a sample to thereby selectively bind hypermethylated DNA.

Claim (Index 12):
A method for selectively binding methylated DNA, comprising:\n contacting a sample containing methylated DNA with a CG-region binding molecule-conjugated resin, wherein said CG-region binding molecule is conjugated to said resin with a crosslinker.

Metadata:
- Claim Count in Document: 21.0
- Percentile: 90.0
- Lexical Diversity: 1.57407
- Patent Class: 536.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15547173', '14113371', '10416381', '12708520', '15117164']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.5850028997404675
- 35 USC 102 Novelty (BERT): 0.5160801879462982
- Combined Prediction Score: 0.5781106285610506
- Mean Citation Score: 207.053656
- Max Citation Score: 307.42685
- Similarity Product: 204.0808278783261

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test