PATENT CLAIM ANALYSIS

Application Number: 15759723
Application Type: Utility
Filing Date: 2018-03
Publication Date: 2018-09
Patent Classification: ["424", "085200"]

Abstract:
This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor.

Claim (Index 49):
A method comprising:\n (a) obtaining a blood sample from a subject; and (b) culturing a population of NK cells of the blood sample in a medium to obtain a population comprising an adaptive NK cell, wherein the medium comprises\n (i) one or more of IL-15, IL-21, and a Notch ligand; \n (ii) a CMV peptide-supplemented mature dendritic cell; \n (iii) autologous monocytes and IL-15 and wherein the subject is CMV seropositive; or \n (iv) at least one of rapamycin and an activator of CD16 signaling; \n wherein the adaptive NK cell is CD56 dim  and is one or more of NKG2C +  and TIGIT low .

Metadata:
- Claim Count in Document: 5.0
- Percentile: 90.0
- Lexical Diversity: 1.91667
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['12855203', '13865762', '13946266', '14547084', '15167166']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.6726953619102328
- 35 USC 102 Novelty (BERT): 0.5350746946889648
- Combined Prediction Score: 0.6589332951881061
- Mean Citation Score: 332.60156
- Max Citation Score: 374.96857
- Similarity Product: 275.524551419378

Labels:
- Claim Label 101: 1
- Claim Label 102: 0
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 0
- Label 101 Adjusted: 1

Dataset: test