PATENT CLAIM ANALYSIS

Application Number: 16007865
Application Type: Utility
Filing Date: 2018-06
Publication Date: 2018-10
Patent Classification: ["514", "571000"]

Abstract:
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease.

Claim (Index 1):
A method for treatment of a liver disorder, comprising administering to a subject in need thereof a compound of General Formula (I) in which: X1 represents a halogen, a R1, or G1-R1 group; A represents a CH\u2550CH or a CH2-CH2 group; X2 represents a G2-R2 group; G1 and G2, identical or different, represent an atom of oxygen or sulfur; R1 represents a hydrogen atom, an unsubstituted alkyl group, an aryl group or an alkyl group that is substituted by one or more halogen atoms, an alkoxy or an alkylthio group, cycloalkyl groups, cycloalkylthio groups or heterocyclic groups; R2 represents an alkyl group substituted by at least a \u2014COOR3 group, wherein R3 represents a hydrogen atom, or an alkyl group that is substituted or not by one or more halogen atoms, cycloalkyl groups, or heterocyclic groups; R4 and R5, identical or different, representing an alkyl group that is substituted or not by one or more halogen atoms, cycloalkyl groups, or heterocyclic groups.

Metadata:
- Claim Count in Document: 26.0
- Percentile: 94.0
- Lexical Diversity: 1.44444
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: True
- Related Applications: ['14523191', '14933335', '15413963', '14288482', '13511170']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.8380848955453428
- 35 USC 102 Novelty (BERT): 0.6907655150607105
- Combined Prediction Score: 0.8233529574968796
- Mean Citation Score: 638.4258000000002
- Max Citation Score: 749.5992
- Similarity Product: 697.9048203366281

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test