PATENT CLAIM ANALYSIS

Application Number: 15774622
Application Type: Utility
Filing Date: 2018-05
Publication Date: 2018-11
Patent Classification: ["514", "007300"]

Abstract:
Co-agonists of the glucagon and GLP-1 receptors are described.

Claim (Index 1):
A co-agonist peptide comprising a peptide selected from following peptides SEQ ID NO: Name Sequence \u20031 PD17 HS V G N F W SDYSKYLDSRRAQDFVQWLMLT-CONH 2   \u20032 PD18 HSQGTFTSDYSKY VED RRA H DFVQWLMNT-CONH 2   \u20033 PD19 HSQGTFTSDY R KYLD E R A A W DFVQWLMNT-CONH 2   \u20034 PD20 HSQGTFTSDYSKYL N S WMT QDFVQWLMNT-CONH 2   \u20035 PD21 HSQGTFTSDYSKYLD IG RAQDFVQWL L NT-CONH 2   \u20036 PD22 HSQGTFTSDYSKYLDS LM AQDFVQWLMST-CONH 2   \u20037 PD23 HSQGTFTSDYSKYLD W RRAQDFVQWL L NT-CONH 2   \u20038 PD24 HSQGTFTSDY I K L LDSRRAQDFVQWLMNT-CONH 2   \u20039 PD25 HSQGTFTSDYSKYLD A RRAQDFVQWL IR T-CONH 2   10 PD26 HSQGTFTSDYSKYLD V RRAQDFVQWLMNT-CONH 2   11 PD27 HSQGTFTSDYSKYLD EL RA Y DFVQWLMNT-CONH 2   12 PD28 HSQGTFTSDYSKYLD YM RA Y DFVQWLMNT-CONH 2   13 PD29 HSQGTFTSDYSKYLDSRRA H DFVQWL L NT-CONH 2   14 PD30 HSQGTFTSDYSKYLDSRRAQDFVQWLMN P -CONH 2   15 PD31 HSQGTFTSDYSKYLDSRRAQDFVQWL I N Y -CONH 2   16 PD32 IN H E Q WA FTSDYSKYLDSRRAQDFVQWLMNT-CONH 2   17 PD33 A S MF TF F SDYSKYLDSRRAQDFVQWLM L T-CONH 2   18 PD34 HSQGTF L SDYSK L LDSRRAQDFVQWLM Q T-CONH 2   19 PD35 HSQGTF LH DY YY YLDSRRAQDFVQWLM D T-CONH 2   20 PD36 HSQGTFTSDYSKYLDS I RAQDFVQWLM DT -CONH 2   21 PD37 HSQGTFTSDYSKYLD NK RAQDFVQWLM Q T-CONH 2   22 PD38 HSQGTFTSDYSKYLDSRRAQDFV D WLMN E -CONH 2   23 PD39 HSQGTFTSDYSKYLDSRRAQ E FV E WLM DE -CONH 2   24 PD40 HSQGTFTSDYSKYLDSRRAQDFVQWL I NT-CONH 2   25 PD41 KALG Q F TFTSDYSKYLDSRRAQDFVQWLMNT-CONH 2   26 PD42 HSQGTF FH DYSKYLDSRRAQDFVQWL L NT-CONH 2   27 PD43 HSQGTF F SDYS HW LDSRRAQDFVQWLMNT-CONH 2   28 PD44 HSQGTFTSDYSKYLD W RRAQDFVQWL Q NT-CONH 2   29 PD45 HSQGTFTSDYSKYLDS K RA H DFVQWL L NT-CONH 2   30 PD46 HSQGTFTSDYSKYLDSRRAQDF WID LMN T -CONH 2   31 PD47 HSQGTFTSDYSKYLDSRRAQDFV MT SMNT-CONH 2   32 PD48 HSQGTFTSDYSKYLDSRRAQDFV D WL L N A -CONH 2   33 PD49 HSQGTFTSDYSKYLDSRRAQDFV E WLMN N -CONH 2   34 PD50 HSQGTFTSDYSKYLDSRRAQDFV D WL I N S -CONH 2   35 PD51 HS H GTFTSDYSKYLDSRRAQDFVQWLM T T-CONH 2   36 PD52 HSQG I F F SDYSKYLDSRRAQDFVQWLMNT-CONH 2   37 PD53 HSQGTF L SDYSKYLDSRRAQDFVQWLMNT-CONH 2   38 PD54 HSQGTFTSDYS W YLDSRRAQDFVQWLMNT-CONH 2   39 PD55 HSQGTFTSDYSKYLD MQ RA H DFVQWLMNT-CONH 2   40 PD56 HSQGTFTSDYSKYLDSR M A Y DFVQWLMNT-CONH 2   41 PD57 HSQGTFTSDYSKYLDSRRAQDFVQWL L N Q -CONH 2   42 PD58 HSQGTFFSDYSKYLDSRRAQDFVQWL LE T-CONH 2   43 PD59 HSQGTFTSDYSKYLDSRRAQDFVQWL LD S-CONH 2 wherein the L-Serine at position 2 is replaced with Val, Ile, Asp, Glu, Met, Trp, Asn, D-Ala, D-Ser, or \u03b1-aminoisobutyric acid (aib), the Tyrosine at position 10 is replaced with a Lysine residue conjugated to a fatty acid or fatty diacid via a linking moiety, wherein CONH 2  indicates the C-terminal amino acid carboxy group is amidated, and the peptide may comprise 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 additional amino acid substitutions.

Metadata:
- Claim Count in Document: 48.0
- Percentile: 93.0
- Lexical Diversity: 1.0
- Patent Class: 514.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15519565', '15851963', '15248712', '15566338', '15852458']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7295662395841468
- 35 USC 102 Novelty (BERT): 0.5457481166750057
- Combined Prediction Score: 0.7111844272932327
- Mean Citation Score: 337.990672
- Max Citation Score: 390.14993
- Similarity Product: 272.6335958621061

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 0
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test