PATENT CLAIM ANALYSIS

Application Number: 15906352
Application Type: Utility
Filing Date: 2018-02
Publication Date: 2018-07
Patent Classification: ["424", "450000"]

Abstract:
A liquid crystalline drug delivery system for ocular administration. The drug delivery system, which is mucoadhesive, biocompatible, non-irritating, and tissue permeable, contains nanoparticles stably dispersed in an aqueous solution and can be formulated for sustained release. Also provided are methods for producing the drug delivery system and methods for treating ocular disorders by administering it to a subject.

Claim (Index 1):
A method for producing a liquid crystalline drug delivery system, the method comprising:\n forming a first solution containing a lipidic component and an alcohol, the first solution being maintained at a first temperature; obtaining a second solution that includes a mucoadhesive hydrophilic polymer and a buffer, the second solution being aqueous and maintained at a second temperature; mixing the first solution and the second solution to form a combined nano/micro-dispersion, the mixing accomplished by a high energy mixing process; subjecting the combined nano/micro-dispersion to microfluidization at a third temperature to form a nano-dispersion; and incubating the nano-dispersion at 2-5\u00b0 C. to form a liquid crystalline drug delivery system, wherein a weight ratio between the first solution and the second solution is 1:1 to 1:15.

Metadata:
- Claim Count in Document: 38.0
- Percentile: 88.0
- Lexical Diversity: 1.40426
- Patent Class: 424.0
- Transitional Phrase Type: open
- Component Type: 1
- Foreign Priority: False
- Related Applications: ['15308000', '15660470', '15509083', '12398657', '14399780']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7061929324423903
- 35 USC 102 Novelty (BERT): 0.5544089483153674
- Combined Prediction Score: 0.691014534029688
- Mean Citation Score: 241.6827
- Max Citation Score: 430.7722
- Similarity Product: 339.79896598644257

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 1
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test