PATENT CLAIM ANALYSIS

Application Number: 15744636
Application Type: Utility
Filing Date: 2018-01
Publication Date: 2019-02
Patent Classification: ["546", "224000"]

Abstract:
Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —OR i  or —NR 2a R 2b ; R 3  is hydrogen or substituted or unsubstituted heteroalicyclyl, R 4  is substituted or unsubstituted aralkyl; X is —OR 22  or —NR 23 R 24 ; (wherein R 22  is hydrogen or substituted or unsubstituted C 1-6 alkyl and one of R 23  and R 24  is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R 21  is —OCH 2 CH(CH 3 ) 2  or F; Also disclosed herein is the tartrate salt of N-(4-fluoroben-zyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.

Claim (Index 27):
The method according to  claim 26 , wherein the pyridine or alkali metal carbonates are sodium carbonate or potassium carbonate.

Metadata:
- Claim Count in Document: 46.0
- Percentile: 86.0
- Lexical Diversity: 2.4
- Patent Class: 546.0
- Transitional Phrase Type: none
- Component Type: 0
- Foreign Priority: False
- Related Applications: ['11749115', '11235558', '13081427', '12795547', '11269913']

Analysis Scores:
- 35 USC 101 Eligibility (BERT): 0.7402553899678789
- 35 USC 102 Novelty (BERT): 0.5160532729689237
- Combined Prediction Score: 0.7178351782679834
- Mean Citation Score: 228.97854
- Max Citation Score: 256.33218
- Similarity Product: 158.84164557075977

Labels:
- Claim Label 101: 1
- Claim Label 102: 1
- Claim Label 103: 0
- Claim Label 112: 1
- Combined Label: 1
- Label 101 Adjusted: 1

Dataset: test