Datasets:

rntc

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ncbi_disease_0_shots_train

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The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: A common human skin tumour is caused by activating mutations in beta-catenin. Output:

A common human @@skin tumour## is caused by activating mutations in beta-catenin.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: A common human skin tumour is caused by activating mutations in beta-catenin. Output: [/INST] A common human @@skin tumour## is caused by activating mutations in beta-catenin.

A common human @@skin tumour## is caused by activating mutations in beta-catenin.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: WNT signalling orchestrates a number of developmental programs. Output:

WNT signalling orchestrates a number of developmental programs.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: WNT signalling orchestrates a number of developmental programs. Output: [/INST] WNT signalling orchestrates a number of developmental programs.

WNT signalling orchestrates a number of developmental programs.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In response to this stimulus, cytoplasmic beta-catenin (encoded by CTNNB1) is stabilized, enabling downstream transcriptional activation by members of the LEF/TCF family. Output:

In response to this stimulus, cytoplasmic beta-catenin (encoded by CTNNB1) is stabilized, enabling downstream transcriptional activation by members of the LEF/TCF family.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In response to this stimulus, cytoplasmic beta-catenin (encoded by CTNNB1) is stabilized, enabling downstream transcriptional activation by members of the LEF/TCF family. Output: [/INST] In response to this stimulus, cytoplasmic beta-catenin (encoded by CTNNB1) is stabilized, enabling downstream transcriptional activation by members of the LEF/TCF family.

In response to this stimulus, cytoplasmic beta-catenin (encoded by CTNNB1) is stabilized, enabling downstream transcriptional activation by members of the LEF/TCF family.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: One of the target genes for beta-catenin/TCF encodes c-MYC, explaining why constitutive activation of the WNT pathway can lead to cancer, particularly in the colon. Output:

One of the target genes for beta-catenin/TCF encodes c-MYC, explaining why constitutive activation of the WNT pathway can lead to @@cancer##, particularly in the colon.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: One of the target genes for beta-catenin/TCF encodes c-MYC, explaining why constitutive activation of the WNT pathway can lead to cancer, particularly in the colon. Output: [/INST] One of the target genes for beta-catenin/TCF encodes c-MYC, explaining why constitutive activation of the WNT pathway can lead to @@cancer##, particularly in the colon.

One of the target genes for beta-catenin/TCF encodes c-MYC, explaining why constitutive activation of the WNT pathway can lead to @@cancer##, particularly in the colon.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Most colon cancers arise from mutations in the gene encoding adenomatous polyposis coli (APC), a protein required for ubiquitin-mediated degradation of beta-catenin, but a small percentage of colon and some other cancers harbour beta-catenin-stabilizing mutations. Output:

Most @@colon cancers## arise from mutations in the gene encoding @@adenomatous polyposis coli## (@@APC##), a protein required for ubiquitin-mediated degradation of beta-catenin, but a small percentage of @@colon and some other cancers## harbour beta-catenin-stabilizing mutations.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Most colon cancers arise from mutations in the gene encoding adenomatous polyposis coli (APC), a protein required for ubiquitin-mediated degradation of beta-catenin, but a small percentage of colon and some other cancers harbour beta-catenin-stabilizing mutations. Output: [/INST] Most @@colon cancers## arise from mutations in the gene encoding @@adenomatous polyposis coli## (@@APC##), a protein required for ubiquitin-mediated degradation of beta-catenin, but a small percentage of @@colon and some other cancers## harbour beta-catenin-stabilizing mutations.

Most @@colon cancers## arise from mutations in the gene encoding @@adenomatous polyposis coli## (@@APC##), a protein required for ubiquitin-mediated degradation of beta-catenin, but a small percentage of @@colon and some other cancers## harbour beta-catenin-stabilizing mutations.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Recently, we discovered that transgenic mice expressing an activated beta-catenin are predisposed to developing skin tumours resembling pilomatricomas. Output:

Recently, we discovered that transgenic mice expressing an activated beta-catenin are predisposed to developing @@skin tumours## resembling @@pilomatricomas##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Recently, we discovered that transgenic mice expressing an activated beta-catenin are predisposed to developing skin tumours resembling pilomatricomas. Output: [/INST] Recently, we discovered that transgenic mice expressing an activated beta-catenin are predisposed to developing @@skin tumours## resembling @@pilomatricomas##.

Recently, we discovered that transgenic mice expressing an activated beta-catenin are predisposed to developing @@skin tumours## resembling @@pilomatricomas##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Given that the skin of these adult mice also exhibits signs of de novo hair-follicle morphogenesis, we wondered whether human pilomatricomas might originate from hair matrix cells and whether they might possess beta-catenin-stabilizing mutations. Output:

Given that the skin of these adult mice also exhibits signs of de novo hair-follicle morphogenesis, we wondered whether human @@pilomatricomas## might originate from hair matrix cells and whether they might possess beta-catenin-stabilizing mutations.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Given that the skin of these adult mice also exhibits signs of de novo hair-follicle morphogenesis, we wondered whether human pilomatricomas might originate from hair matrix cells and whether they might possess beta-catenin-stabilizing mutations. Output: [/INST] Given that the skin of these adult mice also exhibits signs of de novo hair-follicle morphogenesis, we wondered whether human @@pilomatricomas## might originate from hair matrix cells and whether they might possess beta-catenin-stabilizing mutations.

Given that the skin of these adult mice also exhibits signs of de novo hair-follicle morphogenesis, we wondered whether human @@pilomatricomas## might originate from hair matrix cells and whether they might possess beta-catenin-stabilizing mutations.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here, we explore the cell origin and aetiology of this common human skin tumour. Output:

Here, we explore the cell origin and aetiology of this common human @@skin tumour##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here, we explore the cell origin and aetiology of this common human skin tumour. Output: [/INST] Here, we explore the cell origin and aetiology of this common human @@skin tumour##.

Here, we explore the cell origin and aetiology of this common human @@skin tumour##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: We found nuclear LEF-1 in the dividing tumour cells, providing biochemical evidence that pilomatricomas are derived from hair matrix cells. Output:

We found nuclear LEF-1 in the dividing @@tumour## cells, providing biochemical evidence that @@pilomatricomas## are derived from hair matrix cells.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: We found nuclear LEF-1 in the dividing tumour cells, providing biochemical evidence that pilomatricomas are derived from hair matrix cells. Output: [/INST] We found nuclear LEF-1 in the dividing @@tumour## cells, providing biochemical evidence that @@pilomatricomas## are derived from hair matrix cells.

We found nuclear LEF-1 in the dividing @@tumour## cells, providing biochemical evidence that @@pilomatricomas## are derived from hair matrix cells.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: At least 75% of these tumours possess mutations affecting the amino-terminal segment, normally involved in phosphorylation-dependent, ubiquitin-mediated degradation of the protein. Output:

At least 75% of these @@tumours## possess mutations affecting the amino-terminal segment, normally involved in phosphorylation-dependent, ubiquitin-mediated degradation of the protein.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: At least 75% of these tumours possess mutations affecting the amino-terminal segment, normally involved in phosphorylation-dependent, ubiquitin-mediated degradation of the protein. Output: [/INST] At least 75% of these @@tumours## possess mutations affecting the amino-terminal segment, normally involved in phosphorylation-dependent, ubiquitin-mediated degradation of the protein.

At least 75% of these @@tumours## possess mutations affecting the amino-terminal segment, normally involved in phosphorylation-dependent, ubiquitin-mediated degradation of the protein.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This percentage of CTNNB1 mutations is greater than in all other human tumours examined thus far, and directly implicates beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis in humans.. Output:

This percentage of CTNNB1 mutations is greater than in all other human @@tumours## examined thus far, and directly implicates beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis in humans..

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This percentage of CTNNB1 mutations is greater than in all other human tumours examined thus far, and directly implicates beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis in humans.. Output: [/INST] This percentage of CTNNB1 mutations is greater than in all other human @@tumours## examined thus far, and directly implicates beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis in humans..

This percentage of CTNNB1 mutations is greater than in all other human @@tumours## examined thus far, and directly implicates beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis in humans..

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE mutations analysis in 711 hemochromatosis probands: evidence for S65C implication in mild form of hemochromatosis. Output:

HFE mutations analysis in 711 @@hemochromatosis## probands: evidence for S65C implication in mild form of @@hemochromatosis##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE mutations analysis in 711 hemochromatosis probands: evidence for S65C implication in mild form of hemochromatosis. Output: [/INST] HFE mutations analysis in 711 @@hemochromatosis## probands: evidence for S65C implication in mild form of @@hemochromatosis##.

HFE mutations analysis in 711 @@hemochromatosis## probands: evidence for S65C implication in mild form of @@hemochromatosis##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Hereditary hemochromatosis (HH) is a common autosomal recessive genetic disorder of iron metabolism. Output:

@@Hereditary hemochromatosis## (@@HH##) is a common @@autosomal recessive genetic disorder## of iron metabolism.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Hereditary hemochromatosis (HH) is a common autosomal recessive genetic disorder of iron metabolism. Output: [/INST] @@Hereditary hemochromatosis## (@@HH##) is a common @@autosomal recessive genetic disorder## of iron metabolism.

@@Hereditary hemochromatosis## (@@HH##) is a common @@autosomal recessive genetic disorder## of iron metabolism.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The HFE candidate gene encoding an HLA class I-like protein involved in HH was identified in 1996. Output:

The HFE candidate gene encoding an HLA class I-like protein involved in @@HH## was identified in 1996.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The HFE candidate gene encoding an HLA class I-like protein involved in HH was identified in 1996. Output: [/INST] The HFE candidate gene encoding an HLA class I-like protein involved in @@HH## was identified in 1996.

The HFE candidate gene encoding an HLA class I-like protein involved in @@HH## was identified in 1996.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two missense mutations have been described C282Y, accounting for 80% to 90% of HH chromosomes, and H63D, which is associated with a milder form of the disease representing 40% to 70% of non-C282Y HH chromosomes. Output:

Two missense mutations have been described C282Y, accounting for 80% to 90% of @@HH## chromosomes, and H63D, which is associated with a milder form of the disease representing 40% to 70% of non-C282Y @@HH## chromosomes.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two missense mutations have been described C282Y, accounting for 80% to 90% of HH chromosomes, and H63D, which is associated with a milder form of the disease representing 40% to 70% of non-C282Y HH chromosomes. Output: [/INST] Two missense mutations have been described C282Y, accounting for 80% to 90% of @@HH## chromosomes, and H63D, which is associated with a milder form of the disease representing 40% to 70% of non-C282Y @@HH## chromosomes.

Two missense mutations have been described C282Y, accounting for 80% to 90% of @@HH## chromosomes, and H63D, which is associated with a milder form of the disease representing 40% to 70% of non-C282Y @@HH## chromosomes.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: We report here on the analysis of C282Y, H63D, and the 193A-- > T substitution leading to the S65C missense substitution in a large series of probands and controls. Output:

We report here on the analysis of C282Y, H63D, and the 193A-- > T substitution leading to the S65C missense substitution in a large series of probands and controls.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: We report here on the analysis of C282Y, H63D, and the 193A-- > T substitution leading to the S65C missense substitution in a large series of probands and controls. Output: [/INST] We report here on the analysis of C282Y, H63D, and the 193A-- > T substitution leading to the S65C missense substitution in a large series of probands and controls.

We report here on the analysis of C282Y, H63D, and the 193A-- > T substitution leading to the S65C missense substitution in a large series of probands and controls.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The results confirm that the C282Y substitution was the main mutation involved in hemochromatosis, accounting for 85% of carrier chromosomes, whereas the H63D substitution represented 39% of the HH chromosomes that did not carry the C282Y mutation. Output:

The results confirm that the C282Y substitution was the main mutation involved in @@hemochromatosis##, accounting for 85% of carrier chromosomes, whereas the H63D substitution represented 39% of the @@HH## chromosomes that did not carry the C282Y mutation.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The results confirm that the C282Y substitution was the main mutation involved in hemochromatosis, accounting for 85% of carrier chromosomes, whereas the H63D substitution represented 39% of the HH chromosomes that did not carry the C282Y mutation. Output: [/INST] The results confirm that the C282Y substitution was the main mutation involved in @@hemochromatosis##, accounting for 85% of carrier chromosomes, whereas the H63D substitution represented 39% of the @@HH## chromosomes that did not carry the C282Y mutation.

The results confirm that the C282Y substitution was the main mutation involved in @@hemochromatosis##, accounting for 85% of carrier chromosomes, whereas the H63D substitution represented 39% of the @@HH## chromosomes that did not carry the C282Y mutation.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In addition, our screening showed that the S65C substitution was significantly enriched in probands with at least one chromosome without an assigned mutation. Output:

In addition, our screening showed that the S65C substitution was significantly enriched in probands with at least one chromosome without an assigned mutation.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In addition, our screening showed that the S65C substitution was significantly enriched in probands with at least one chromosome without an assigned mutation. Output: [/INST] In addition, our screening showed that the S65C substitution was significantly enriched in probands with at least one chromosome without an assigned mutation.

In addition, our screening showed that the S65C substitution was significantly enriched in probands with at least one chromosome without an assigned mutation.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This substitution accounted for 7. Output:

This substitution accounted for 7.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This substitution accounted for 7. Output: [/INST] This substitution accounted for 7.

This substitution accounted for 7.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 8% of HH chromosomes that were neither C282Y nor H63D. Output:

8% of @@HH## chromosomes that were neither C282Y nor H63D.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 8% of HH chromosomes that were neither C282Y nor H63D. Output: [/INST] 8% of @@HH## chromosomes that were neither C282Y nor H63D.

8% of @@HH## chromosomes that were neither C282Y nor H63D.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This enrichment of S65C among HH chromosomes suggests that the S65C substitution is associated with the mild form of hemochromatosis. Output:

This enrichment of S65C among @@HH## chromosomes suggests that the S65C substitution is associated with the mild form of @@hemochromatosis##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This enrichment of S65C among HH chromosomes suggests that the S65C substitution is associated with the mild form of hemochromatosis. Output: [/INST] This enrichment of S65C among @@HH## chromosomes suggests that the S65C substitution is associated with the mild form of @@hemochromatosis##.

This enrichment of S65C among @@HH## chromosomes suggests that the S65C substitution is associated with the mild form of @@hemochromatosis##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Germline BRCA1 alterations in a population-based series of ovarian cancer cases. Output:

Germline BRCA1 alterations in a population-based series of @@ovarian cancer## cases.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Germline BRCA1 alterations in a population-based series of ovarian cancer cases. Output: [/INST] Germline BRCA1 alterations in a population-based series of @@ovarian cancer## cases.

Germline BRCA1 alterations in a population-based series of @@ovarian cancer## cases.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The objective of this study was to provide more accurate frequency estimates of breast cancer susceptibility gene 1 (BRCA1) germline alterations in the ovarian cancer population. Output:

The objective of this study was to provide more accurate frequency estimates of @@breast cancer## susceptibility gene 1 (BRCA1) germline alterations in the @@ovarian cancer## population.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The objective of this study was to provide more accurate frequency estimates of breast cancer susceptibility gene 1 (BRCA1) germline alterations in the ovarian cancer population. Output: [/INST] The objective of this study was to provide more accurate frequency estimates of @@breast cancer## susceptibility gene 1 (BRCA1) germline alterations in the @@ovarian cancer## population.

The objective of this study was to provide more accurate frequency estimates of @@breast cancer## susceptibility gene 1 (BRCA1) germline alterations in the @@ovarian cancer## population.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive ovarian cancer cases. Output:

To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive @@ovarian cancer## cases.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive ovarian cancer cases. Output: [/INST] To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive @@ovarian cancer## cases.

To achieve this, we determined the prevalence of BRCA1 alterations in a population-based series of consecutive @@ovarian cancer## cases.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This is the first population-based ovarian cancer study reporting BRCA1 alterations derived from a comprehensive screen of the entire coding region. Output:

This is the first population-based @@ovarian cancer## study reporting BRCA1 alterations derived from a comprehensive screen of the entire coding region.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This is the first population-based ovarian cancer study reporting BRCA1 alterations derived from a comprehensive screen of the entire coding region. Output: [/INST] This is the first population-based @@ovarian cancer## study reporting BRCA1 alterations derived from a comprehensive screen of the entire coding region.

This is the first population-based @@ovarian cancer## study reporting BRCA1 alterations derived from a comprehensive screen of the entire coding region.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: One hundred and seven ovarian cancer cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing. Output:

One hundred and seven @@ovarian cancer## cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: One hundred and seven ovarian cancer cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing. Output: [/INST] One hundred and seven @@ovarian cancer## cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing.

One hundred and seven @@ovarian cancer## cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two truncating mutations, 962del4 and 3600del11, were identified. Output:

Two truncating mutations, 962del4 and 3600del11, were identified.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two truncating mutations, 962del4 and 3600del11, were identified. Output: [/INST] Two truncating mutations, 962del4 and 3600del11, were identified.

Two truncating mutations, 962del4 and 3600del11, were identified.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Both patients had a family history of breast or ovarian cancer. Output:

Both patients had a family history of @@breast or ovarian cancer##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Both patients had a family history of breast or ovarian cancer. Output: [/INST] Both patients had a family history of @@breast or ovarian cancer##.

Both patients had a family history of @@breast or ovarian cancer##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Several novel as well as previously reported uncharacterized variants were also identified, some of which were associated with a family history of cancer. Output:

Several novel as well as previously reported uncharacterized variants were also identified, some of which were associated with a family history of @@cancer##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Several novel as well as previously reported uncharacterized variants were also identified, some of which were associated with a family history of cancer. Output: [/INST] Several novel as well as previously reported uncharacterized variants were also identified, some of which were associated with a family history of @@cancer##.

Several novel as well as previously reported uncharacterized variants were also identified, some of which were associated with a family history of @@cancer##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The frequency distribution of common polymorphisms was determined in the 91 Caucasian cancer cases in this series and 24 sister controls using allele-specific amplification. Output:

The frequency distribution of common polymorphisms was determined in the 91 Caucasian @@cancer## cases in this series and 24 sister controls using allele-specific amplification.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The frequency distribution of common polymorphisms was determined in the 91 Caucasian cancer cases in this series and 24 sister controls using allele-specific amplification. Output: [/INST] The frequency distribution of common polymorphisms was determined in the 91 Caucasian @@cancer## cases in this series and 24 sister controls using allele-specific amplification.

The frequency distribution of common polymorphisms was determined in the 91 Caucasian @@cancer## cases in this series and 24 sister controls using allele-specific amplification.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The rare form of the Q356R polymorphism was significantly (P = 0. Output:

The rare form of the Q356R polymorphism was significantly (P = 0.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The rare form of the Q356R polymorphism was significantly (P = 0. Output: [/INST] The rare form of the Q356R polymorphism was significantly (P = 0.

The rare form of the Q356R polymorphism was significantly (P = 0.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 03) associated with a family history of ovarian cancer, suggesting that this polymorphism may influence ovarian cancer risk. Output:

03) associated with a family history of @@ovarian cancer##, suggesting that this polymorphism may influence @@ovarian cancer## risk.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 03) associated with a family history of ovarian cancer, suggesting that this polymorphism may influence ovarian cancer risk. Output: [/INST] 03) associated with a family history of @@ovarian cancer##, suggesting that this polymorphism may influence @@ovarian cancer## risk.

03) associated with a family history of @@ovarian cancer##, suggesting that this polymorphism may influence @@ovarian cancer## risk.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In summary, our data suggest a role for some uncharacterized variants and rare forms of polymorphisms in determining ovarian cancer risk, and highlight the necessity to screen for missense alterations as well as truncating mutations in this population. Output:

In summary, our data suggest a role for some uncharacterized variants and rare forms of polymorphisms in determining @@ovarian cancer## risk, and highlight the necessity to screen for missense alterations as well as truncating mutations in this population.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In summary, our data suggest a role for some uncharacterized variants and rare forms of polymorphisms in determining ovarian cancer risk, and highlight the necessity to screen for missense alterations as well as truncating mutations in this population. Output: [/INST] In summary, our data suggest a role for some uncharacterized variants and rare forms of polymorphisms in determining @@ovarian cancer## risk, and highlight the necessity to screen for missense alterations as well as truncating mutations in this population.

In summary, our data suggest a role for some uncharacterized variants and rare forms of polymorphisms in determining @@ovarian cancer## risk, and highlight the necessity to screen for missense alterations as well as truncating mutations in this population.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Output:

Identification of APC2, a homologue of the @@adenomatous polyposis coli tumour## suppressor.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Output: [/INST] Identification of APC2, a homologue of the @@adenomatous polyposis coli tumour## suppressor.

Identification of APC2, a homologue of the @@adenomatous polyposis coli tumour## suppressor.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The adenomatous polyposis coli (APC) tumour-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin. Output:

The @@adenomatous polyposis coli (APC) tumour##-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The adenomatous polyposis coli (APC) tumour-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin. Output: [/INST] The @@adenomatous polyposis coli (APC) tumour##-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin.

The @@adenomatous polyposis coli (APC) tumour##-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Complex formation induces the rapid degradation of betacatenin. Output:

Complex formation induces the rapid degradation of betacatenin.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Complex formation induces the rapid degradation of betacatenin. Output: [/INST] Complex formation induces the rapid degradation of betacatenin.

Complex formation induces the rapid degradation of betacatenin.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In colon carcinoma cells, loss of APC leads to the accumulation of betacatenin in the nucleus, where it binds to and activates the Tcf-4 transcription factor (reviewed in [1] [2]). Output:

In @@colon carcinoma## cells, loss of APC leads to the accumulation of betacatenin in the nucleus, where it binds to and activates the Tcf-4 transcription factor (reviewed in [1] [2]).

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In colon carcinoma cells, loss of APC leads to the accumulation of betacatenin in the nucleus, where it binds to and activates the Tcf-4 transcription factor (reviewed in [1] [2]). Output: [/INST] In @@colon carcinoma## cells, loss of APC leads to the accumulation of betacatenin in the nucleus, where it binds to and activates the Tcf-4 transcription factor (reviewed in [1] [2]).

In @@colon carcinoma## cells, loss of APC leads to the accumulation of betacatenin in the nucleus, where it binds to and activates the Tcf-4 transcription factor (reviewed in [1] [2]).

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here, we report the identification and genomic structure of APC homologues. Output:

Here, we report the identification and genomic structure of APC homologues.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here, we report the identification and genomic structure of APC homologues. Output: [/INST] Here, we report the identification and genomic structure of APC homologues.

Here, we report the identification and genomic structure of APC homologues.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin. Output:

Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin. Output: [/INST] Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin.

Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Like APC, APC2 regulates the formation of active betacatenin-Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- colon carcinoma cells. Output:

Like APC, APC2 regulates the formation of active betacatenin-Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- @@colon carcinoma## cells.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Like APC, APC2 regulates the formation of active betacatenin-Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- colon carcinoma cells. Output: [/INST] Like APC, APC2 regulates the formation of active betacatenin-Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- @@colon carcinoma## cells.

Like APC, APC2 regulates the formation of active betacatenin-Tcf complexes, as demonstrated using transient transcriptional activation assays in APC -/- @@colon carcinoma## cells.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Human APC2 maps to chromosome 19p13. Output:

Human APC2 maps to chromosome 19p13.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Human APC2 maps to chromosome 19p13. Output: [/INST] Human APC2 maps to chromosome 19p13.

Human APC2 maps to chromosome 19p13.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 3. Output:

3.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 3. Output: [/INST] 3.

3.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: APC and APC2 may therefore have comparable functions in development and cancer. Output:

APC and APC2 may therefore have comparable functions in development and @@cancer##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: APC and APC2 may therefore have comparable functions in development and cancer. Output: [/INST] APC and APC2 may therefore have comparable functions in development and @@cancer##.

APC and APC2 may therefore have comparable functions in development and @@cancer##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Familial deficiency of the seventh component of complement associated with recurrent bacteremic infections due to Neisseria. Output:

@@Familial deficiency of the seventh component of complement## associated with recurrent @@bacteremic infections due to Neisseria##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Familial deficiency of the seventh component of complement associated with recurrent bacteremic infections due to Neisseria. Output: [/INST] @@Familial deficiency of the seventh component of complement## associated with recurrent @@bacteremic infections due to Neisseria##.

@@Familial deficiency of the seventh component of complement## associated with recurrent @@bacteremic infections due to Neisseria##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The serum of a 29-year old woman with a recent episode of disseminated gonococcal infection and a history of meningococcal meningitis and arthritis as a child was found to lack serum hemolytic complement activity. Output:

The serum of a 29-year old woman with a recent episode of @@disseminated gonococcal infection## and a history of @@meningococcal meningitis## and @@arthritis## as a child was found to lack serum hemolytic complement activity.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The serum of a 29-year old woman with a recent episode of disseminated gonococcal infection and a history of meningococcal meningitis and arthritis as a child was found to lack serum hemolytic complement activity. Output: [/INST] The serum of a 29-year old woman with a recent episode of @@disseminated gonococcal infection## and a history of @@meningococcal meningitis## and @@arthritis## as a child was found to lack serum hemolytic complement activity.

The serum of a 29-year old woman with a recent episode of @@disseminated gonococcal infection## and a history of @@meningococcal meningitis## and @@arthritis## as a child was found to lack serum hemolytic complement activity.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The seventh component of complement (C7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment. Output:

The seventh component of complement (C7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The seventh component of complement (C7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment. Output: [/INST] The seventh component of complement (C7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment.

The seventh component of complement (C7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Her fresh serum lacked complement-mediated bactericidal activity against Neisseria gonorrhoeae, but the addition of fresh normal serum or purified C7 restored bactericidal activity as well as hemolytic activity. Output:

Her fresh serum lacked complement-mediated bactericidal activity against Neisseria gonorrhoeae, but the addition of fresh normal serum or purified C7 restored bactericidal activity as well as hemolytic activity.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Her fresh serum lacked complement-mediated bactericidal activity against Neisseria gonorrhoeae, but the addition of fresh normal serum or purified C7 restored bactericidal activity as well as hemolytic activity. Output: [/INST] Her fresh serum lacked complement-mediated bactericidal activity against Neisseria gonorrhoeae, but the addition of fresh normal serum or purified C7 restored bactericidal activity as well as hemolytic activity.

Her fresh serum lacked complement-mediated bactericidal activity against Neisseria gonorrhoeae, but the addition of fresh normal serum or purified C7 restored bactericidal activity as well as hemolytic activity.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The absence of functional C7 activity could not be accounted for on the basis of an inhibitor. Output:

The @@absence of functional C7## activity could not be accounted for on the basis of an inhibitor.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The absence of functional C7 activity could not be accounted for on the basis of an inhibitor. Output: [/INST] The @@absence of functional C7## activity could not be accounted for on the basis of an inhibitor.

The @@absence of functional C7## activity could not be accounted for on the basis of an inhibitor.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Opsonization and generation of chemotactic activity functioned normally. Output:

Opsonization and generation of chemotactic activity functioned normally.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Opsonization and generation of chemotactic activity functioned normally. Output: [/INST] Opsonization and generation of chemotactic activity functioned normally.

Opsonization and generation of chemotactic activity functioned normally.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Complete absence of C7 was also found in one sibling who had the clinical syndrome of meningococcal meningitis and arthritis as a child and in this siblings clinically well eight-year-old son. Output:

@@Complete absence of C7## was also found in one sibling who had the clinical syndrome of @@meningococcal meningitis## and @@arthritis## as a child and in this siblings clinically well eight-year-old son.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Complete absence of C7 was also found in one sibling who had the clinical syndrome of meningococcal meningitis and arthritis as a child and in this siblings clinically well eight-year-old son. Output: [/INST] @@Complete absence of C7## was also found in one sibling who had the clinical syndrome of @@meningococcal meningitis## and @@arthritis## as a child and in this siblings clinically well eight-year-old son.

@@Complete absence of C7## was also found in one sibling who had the clinical syndrome of @@meningococcal meningitis## and @@arthritis## as a child and in this siblings clinically well eight-year-old son.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HLA histocompatibility typing of the family members did not demonstrate evidence for genetic linkage of C7 deficiency with the major histocompatibility loci. Output:

HLA histocompatibility typing of the family members did not demonstrate evidence for genetic linkage of @@C7 deficiency## with the major histocompatibility loci.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HLA histocompatibility typing of the family members did not demonstrate evidence for genetic linkage of C7 deficiency with the major histocompatibility loci. Output: [/INST] HLA histocompatibility typing of the family members did not demonstrate evidence for genetic linkage of @@C7 deficiency## with the major histocompatibility loci.

HLA histocompatibility typing of the family members did not demonstrate evidence for genetic linkage of @@C7 deficiency## with the major histocompatibility loci.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This report represents the first cases of C7 deficiency associated with infectious complications and suggests that bactericidal activity may be important in host defense against bacteremic neisseria infections. Output:

This report represents the first cases of @@C7 deficiency## associated with infectious complications and suggests that bactericidal activity may be important in host defense against @@bacteremic neisseria infections##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: This report represents the first cases of C7 deficiency associated with infectious complications and suggests that bactericidal activity may be important in host defense against bacteremic neisseria infections. Output: [/INST] This report represents the first cases of @@C7 deficiency## associated with infectious complications and suggests that bactericidal activity may be important in host defense against @@bacteremic neisseria infections##.

This report represents the first cases of @@C7 deficiency## associated with infectious complications and suggests that bactericidal activity may be important in host defense against @@bacteremic neisseria infections##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: GCH1 mutation in a patient with adult-onset oromandibular dystonia. Output:

GCH1 mutation in a patient with adult-onset @@oromandibular dystonia##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: GCH1 mutation in a patient with adult-onset oromandibular dystonia. Output: [/INST] GCH1 mutation in a patient with adult-onset @@oromandibular dystonia##.

GCH1 mutation in a patient with adult-onset @@oromandibular dystonia##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The authors report a mutation in exon 5 of GCH1 in a patient with adult-onset oromandibular dystonia and no obvious family history of dystonia. Output:

The authors report a mutation in exon 5 of GCH1 in a patient with adult-onset @@oromandibular dystonia## and no obvious family history of @@dystonia##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The authors report a mutation in exon 5 of GCH1 in a patient with adult-onset oromandibular dystonia and no obvious family history of dystonia. Output: [/INST] The authors report a mutation in exon 5 of GCH1 in a patient with adult-onset @@oromandibular dystonia## and no obvious family history of @@dystonia##.

The authors report a mutation in exon 5 of GCH1 in a patient with adult-onset @@oromandibular dystonia## and no obvious family history of @@dystonia##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The patient responded positively to treatment with L-dopa. Output:

The patient responded positively to treatment with L-dopa.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The patient responded positively to treatment with L-dopa. Output: [/INST] The patient responded positively to treatment with L-dopa.

The patient responded positively to treatment with L-dopa.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These findings demonstrate that GCH1 mutations must be considered even in patients with dystonic symptoms not typical of dopa-responsive dystonia. Output:

These findings demonstrate that GCH1 mutations must be considered even in patients with @@dystonic## symptoms not typical of @@dopa-responsive dystonia##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These findings demonstrate that GCH1 mutations must be considered even in patients with dystonic symptoms not typical of dopa-responsive dystonia. Output: [/INST] These findings demonstrate that GCH1 mutations must be considered even in patients with @@dystonic## symptoms not typical of @@dopa-responsive dystonia##.

These findings demonstrate that GCH1 mutations must be considered even in patients with @@dystonic## symptoms not typical of @@dopa-responsive dystonia##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells. Output:

The @@hereditary hemochromatosis## protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells. Output: [/INST] The @@hereditary hemochromatosis## protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells.

The @@hereditary hemochromatosis## protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE is the protein product of the gene mutated in the autosomal recessive disease hereditary hemochromatosis (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., Prasss, C. E ., Quintana, L., Starnes, S. M ., Schatzman, R. C ., Brunke, K. J ., Drayna, D. T., Risch, N. J ., Bacon, B. R ., and Wolff, R. R . Output:

HFE is the protein product of the gene mutated in the @@autosomal recessive disease## @@hereditary hemochromatosis## (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., Prasss, C. E ., Quintana, L., Starnes, S. M ., Schatzman, R. C ., Brunke, K. J ., Drayna, D. T., Risch, N. J ., Bacon, B. R ., and Wolff, R. R .

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE is the protein product of the gene mutated in the autosomal recessive disease hereditary hemochromatosis (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., Prasss, C. E ., Quintana, L., Starnes, S. M ., Schatzman, R. C ., Brunke, K. J ., Drayna, D. T., Risch, N. J ., Bacon, B. R ., and Wolff, R. R . Output: [/INST] HFE is the protein product of the gene mutated in the @@autosomal recessive disease## @@hereditary hemochromatosis## (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., Prasss, C. E ., Quintana, L., Starnes, S. M ., Schatzman, R. C ., Brunke, K. J ., Drayna, D. T., Risch, N. J ., Bacon, B. R ., and Wolff, R. R .

HFE is the protein product of the gene mutated in the @@autosomal recessive disease## @@hereditary hemochromatosis## (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, G. A., Moeller, N., Moore, T., Morikang, E., Prasss, C. E ., Quintana, L., Starnes, S. M ., Schatzman, R. C ., Brunke, K. J ., Drayna, D. T., Risch, N. J ., Bacon, B. R ., and Wolff, R. R .

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: (1996) Nat. Output:

(1996) Nat.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: (1996) Nat. Output: [/INST] (1996) Nat.

(1996) Nat.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Genet. Output:

Genet.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Genet. Output: [/INST] Genet.

Genet.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 13, 399-408). Output:

13, 399-408).

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 13, 399-408). Output: [/INST] 13, 399-408).

13, 399-408).

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: At the cell surface, HFE complexes with transferrin receptor (TfR), increasing the dissociation constant of transferrin (Tf) for its receptor 10-fold (Gross, C. N ., Irrinki, A., Feder, J. N ., and Enns, C. A . Output:

At the cell surface, HFE complexes with transferrin receptor (TfR), increasing the dissociation constant of transferrin (Tf) for its receptor 10-fold (Gross, C. N ., Irrinki, A., Feder, J. N ., and Enns, C. A .

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: At the cell surface, HFE complexes with transferrin receptor (TfR), increasing the dissociation constant of transferrin (Tf) for its receptor 10-fold (Gross, C. N ., Irrinki, A., Feder, J. N ., and Enns, C. A . Output: [/INST] At the cell surface, HFE complexes with transferrin receptor (TfR), increasing the dissociation constant of transferrin (Tf) for its receptor 10-fold (Gross, C. N ., Irrinki, A., Feder, J. N ., and Enns, C. A .

At the cell surface, HFE complexes with transferrin receptor (TfR), increasing the dissociation constant of transferrin (Tf) for its receptor 10-fold (Gross, C. N ., Irrinki, A., Feder, J. N ., and Enns, C. A .

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: (1998) J. Biol. Output:

(1998) J. Biol.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: (1998) J. Biol. Output: [/INST] (1998) J. Biol.

(1998) J. Biol.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Chem. Output:

Chem.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Chem. Output: [/INST] Chem.

Chem.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 273, 22068-22074; Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebron, J. Output:

273, 22068-22074; Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebron, J.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: 273, 22068-22074; Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebron, J. Output: [/INST] 273, 22068-22074; Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebron, J.

273, 22068-22074; Feder, J. N., Penny, D. M., Irrinki, A., Lee, V. K., Lebron, J.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., and Schatzman, R. C. (1998) Proc. Output:

A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., and Schatzman, R. C. (1998) Proc.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., and Schatzman, R. C. (1998) Proc. Output: [/INST] A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., and Schatzman, R. C. (1998) Proc.

A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P. J., and Schatzman, R. C. (1998) Proc.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Natl . Output:

Natl .

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Natl . Output: [/INST] Natl .

Natl .

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Acad. Output:

Acad.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Acad. Output: [/INST] Acad.

Acad.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Sci. Output:

Sci.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Sci. Output: [/INST] Sci.

Sci.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: U S A 95, 1472-1477). Output:

U S A 95, 1472-1477).

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: U S A 95, 1472-1477). Output: [/INST] U S A 95, 1472-1477).

U S A 95, 1472-1477).

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE does not remain at the cell surface, but traffics with TfR to Tf-positive internal compartments (Gross et al., 1998). Output:

HFE does not remain at the cell surface, but traffics with TfR to Tf-positive internal compartments (Gross et al., 1998).

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE does not remain at the cell surface, but traffics with TfR to Tf-positive internal compartments (Gross et al., 1998). Output: [/INST] HFE does not remain at the cell surface, but traffics with TfR to Tf-positive internal compartments (Gross et al., 1998).

HFE does not remain at the cell surface, but traffics with TfR to Tf-positive internal compartments (Gross et al., 1998).

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Using a HeLa cell line in which the expression of HFE is controlled by tetracycline, we show that the expression of HFE reduces 55Fe uptake from Tf by 33% but does not affect the endocytic or exocytic rates of TfR cycling. Output:

Using a HeLa cell line in which the expression of HFE is controlled by tetracycline, we show that the expression of HFE reduces 55Fe uptake from Tf by 33% but does not affect the endocytic or exocytic rates of TfR cycling.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Using a HeLa cell line in which the expression of HFE is controlled by tetracycline, we show that the expression of HFE reduces 55Fe uptake from Tf by 33% but does not affect the endocytic or exocytic rates of TfR cycling. Output: [/INST] Using a HeLa cell line in which the expression of HFE is controlled by tetracycline, we show that the expression of HFE reduces 55Fe uptake from Tf by 33% but does not affect the endocytic or exocytic rates of TfR cycling.

Using a HeLa cell line in which the expression of HFE is controlled by tetracycline, we show that the expression of HFE reduces 55Fe uptake from Tf by 33% but does not affect the endocytic or exocytic rates of TfR cycling.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Therefore, HFE appears to reduce cellular acquisition of iron from Tf within endocytic compartments. Output:

Therefore, HFE appears to reduce cellular acquisition of iron from Tf within endocytic compartments.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Therefore, HFE appears to reduce cellular acquisition of iron from Tf within endocytic compartments. Output: [/INST] Therefore, HFE appears to reduce cellular acquisition of iron from Tf within endocytic compartments.

Therefore, HFE appears to reduce cellular acquisition of iron from Tf within endocytic compartments.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE specifically reduces iron uptake from Tf, as non-Tf-mediated iron uptake from Fe-nitrilotriacetic acid is not altered. Output:

HFE specifically reduces iron uptake from Tf, as non-Tf-mediated iron uptake from Fe-nitrilotriacetic acid is not altered.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: HFE specifically reduces iron uptake from Tf, as non-Tf-mediated iron uptake from Fe-nitrilotriacetic acid is not altered. Output: [/INST] HFE specifically reduces iron uptake from Tf, as non-Tf-mediated iron uptake from Fe-nitrilotriacetic acid is not altered.

HFE specifically reduces iron uptake from Tf, as non-Tf-mediated iron uptake from Fe-nitrilotriacetic acid is not altered.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These results explain the decreased ferritin levels seen in our HeLa cell system and demonstrate the specific control of HFE over the Tf-mediated pathway of iron uptake. Output:

These results explain the decreased ferritin levels seen in our HeLa cell system and demonstrate the specific control of HFE over the Tf-mediated pathway of iron uptake.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These results explain the decreased ferritin levels seen in our HeLa cell system and demonstrate the specific control of HFE over the Tf-mediated pathway of iron uptake. Output: [/INST] These results explain the decreased ferritin levels seen in our HeLa cell system and demonstrate the specific control of HFE over the Tf-mediated pathway of iron uptake.

These results explain the decreased ferritin levels seen in our HeLa cell system and demonstrate the specific control of HFE over the Tf-mediated pathway of iron uptake.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These results also have implications for the understanding of cellular iron homeostasis in organs such as the liver, pancreas, heart, and spleen that are iron loaded in hereditary hemochromatotic individuals lacking functional HFE. Output:

These results also have implications for the understanding of cellular iron homeostasis in organs such as the liver, pancreas, heart, and spleen that are iron loaded in @@hereditary hemochromatotic## individuals lacking functional HFE.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: These results also have implications for the understanding of cellular iron homeostasis in organs such as the liver, pancreas, heart, and spleen that are iron loaded in hereditary hemochromatotic individuals lacking functional HFE. Output: [/INST] These results also have implications for the understanding of cellular iron homeostasis in organs such as the liver, pancreas, heart, and spleen that are iron loaded in @@hereditary hemochromatotic## individuals lacking functional HFE.

These results also have implications for the understanding of cellular iron homeostasis in organs such as the liver, pancreas, heart, and spleen that are iron loaded in @@hereditary hemochromatotic## individuals lacking functional HFE.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population. Output:

Mutation and haplotype studies of @@familial Mediterranean fever## reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population. Output: [/INST] Mutation and haplotype studies of @@familial Mediterranean fever## reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population.

Mutation and haplotype studies of @@familial Mediterranean fever## reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Familial Mediterranean fever (FMF) is a recessive disorder characterized by episodes of fever with serositis or synovitis. Output:

@@Familial Mediterranean fever## (@@FMF##) is a @@recessive disorder## characterized by episodes of fever with @@serositis## or @@synovitis##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Familial Mediterranean fever (FMF) is a recessive disorder characterized by episodes of fever with serositis or synovitis. Output: [/INST] @@Familial Mediterranean fever## (@@FMF##) is a @@recessive disorder## characterized by episodes of fever with @@serositis## or @@synovitis##.

@@Familial Mediterranean fever## (@@FMF##) is a @@recessive disorder## characterized by episodes of fever with @@serositis## or @@synovitis##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The FMF gene (MEFV) was cloned recently, and four missense mutations were identified. Output:

The @@FMF## gene (MEFV) was cloned recently, and four missense mutations were identified.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The FMF gene (MEFV) was cloned recently, and four missense mutations were identified. Output: [/INST] The @@FMF## gene (MEFV) was cloned recently, and four missense mutations were identified.

The @@FMF## gene (MEFV) was cloned recently, and four missense mutations were identified.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here we present data from non-Ashkenazi Jewish and Arab patients in whom we had not originally found mutations and from a new, more ethnically diverse panel. Output:

Here we present data from non-Ashkenazi Jewish and Arab patients in whom we had not originally found mutations and from a new, more ethnically diverse panel.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Here we present data from non-Ashkenazi Jewish and Arab patients in whom we had not originally found mutations and from a new, more ethnically diverse panel. Output: [/INST] Here we present data from non-Ashkenazi Jewish and Arab patients in whom we had not originally found mutations and from a new, more ethnically diverse panel.

Here we present data from non-Ashkenazi Jewish and Arab patients in whom we had not originally found mutations and from a new, more ethnically diverse panel.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among 90 symptomatic mutation-positive individuals, 11 mutations accounted for 79% of carrier chromosomes. Output:

Among 90 symptomatic mutation-positive individuals, 11 mutations accounted for 79% of carrier chromosomes.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among 90 symptomatic mutation-positive individuals, 11 mutations accounted for 79% of carrier chromosomes. Output: [/INST] Among 90 symptomatic mutation-positive individuals, 11 mutations accounted for 79% of carrier chromosomes.

Among 90 symptomatic mutation-positive individuals, 11 mutations accounted for 79% of carrier chromosomes.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Of the two mutations that are novel, one alters the same residue (680) as a previously known mutation, and the other (P369S) is located in exon 3. Output:

Of the two mutations that are novel, one alters the same residue (680) as a previously known mutation, and the other (P369S) is located in exon 3.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Of the two mutations that are novel, one alters the same residue (680) as a previously known mutation, and the other (P369S) is located in exon 3. Output: [/INST] Of the two mutations that are novel, one alters the same residue (680) as a previously known mutation, and the other (P369S) is located in exon 3.

Of the two mutations that are novel, one alters the same residue (680) as a previously known mutation, and the other (P369S) is located in exon 3.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Consistent with another recent report, the E148Q mutation was observed in patients of several ethnicities and on multiple microsatellite haplotypes, but haplotype data indicate an ancestral relationships between non-Jewish Italian and Ashkenazi Jewish patients with FMF and other affected populations. Output:

Consistent with another recent report, the E148Q mutation was observed in patients of several ethnicities and on multiple microsatellite haplotypes, but haplotype data indicate an ancestral relationships between non-Jewish Italian and Ashkenazi Jewish patients with @@FMF## and other affected populations.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Consistent with another recent report, the E148Q mutation was observed in patients of several ethnicities and on multiple microsatellite haplotypes, but haplotype data indicate an ancestral relationships between non-Jewish Italian and Ashkenazi Jewish patients with FMF and other affected populations. Output: [/INST] Consistent with another recent report, the E148Q mutation was observed in patients of several ethnicities and on multiple microsatellite haplotypes, but haplotype data indicate an ancestral relationships between non-Jewish Italian and Ashkenazi Jewish patients with @@FMF## and other affected populations.

Consistent with another recent report, the E148Q mutation was observed in patients of several ethnicities and on multiple microsatellite haplotypes, but haplotype data indicate an ancestral relationships between non-Jewish Italian and Ashkenazi Jewish patients with @@FMF## and other affected populations.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among approximately 200 anonymous Ashkenazi Jewish DNA samples, the MEFV carrier frequency was 21%, with E148Q the most common mutation. Output:

Among approximately 200 anonymous Ashkenazi Jewish DNA samples, the MEFV carrier frequency was 21%, with E148Q the most common mutation.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among approximately 200 anonymous Ashkenazi Jewish DNA samples, the MEFV carrier frequency was 21%, with E148Q the most common mutation. Output: [/INST] Among approximately 200 anonymous Ashkenazi Jewish DNA samples, the MEFV carrier frequency was 21%, with E148Q the most common mutation.

Among approximately 200 anonymous Ashkenazi Jewish DNA samples, the MEFV carrier frequency was 21%, with E148Q the most common mutation.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Several lines of evidence indicate reduced penetrance among Ashkenazi Jews, especially for E148Q, P369S, and K695R. Output:

Several lines of evidence indicate reduced penetrance among Ashkenazi Jews, especially for E148Q, P369S, and K695R.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Several lines of evidence indicate reduced penetrance among Ashkenazi Jews, especially for E148Q, P369S, and K695R. Output: [/INST] Several lines of evidence indicate reduced penetrance among Ashkenazi Jews, especially for E148Q, P369S, and K695R.

Several lines of evidence indicate reduced penetrance among Ashkenazi Jews, especially for E148Q, P369S, and K695R.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Nevertheless, E148Q helps account for recessive inheritance in an Ashkenazi family previously reported as an unusual case of dominantly inherited FMF. Output:

Nevertheless, E148Q helps account for recessive inheritance in an Ashkenazi family previously reported as an unusual case of dominantly inherited @@FMF##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Nevertheless, E148Q helps account for recessive inheritance in an Ashkenazi family previously reported as an unusual case of dominantly inherited FMF. Output: [/INST] Nevertheless, E148Q helps account for recessive inheritance in an Ashkenazi family previously reported as an unusual case of dominantly inherited @@FMF##.

Nevertheless, E148Q helps account for recessive inheritance in an Ashkenazi family previously reported as an unusual case of dominantly inherited @@FMF##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The presence of three frequent MEFV mutations in multiple Mediterranean populations strongly suggests a heterozygote advantage in this geographic region. Output:

The presence of three frequent MEFV mutations in multiple Mediterranean populations strongly suggests a heterozygote advantage in this geographic region.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: The presence of three frequent MEFV mutations in multiple Mediterranean populations strongly suggests a heterozygote advantage in this geographic region. Output: [/INST] The presence of three frequent MEFV mutations in multiple Mediterranean populations strongly suggests a heterozygote advantage in this geographic region.

The presence of three frequent MEFV mutations in multiple Mediterranean populations strongly suggests a heterozygote advantage in this geographic region.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance. Output:

@@Autoimmune lymphoproliferative syndrome## with defective Fas: genotype influences penetrance.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance. Output: [/INST] @@Autoimmune lymphoproliferative syndrome## with defective Fas: genotype influences penetrance.

@@Autoimmune lymphoproliferative syndrome## with defective Fas: genotype influences penetrance.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte homeostasis and immunological tolerance. Output:

@@Autoimmune lymphoproliferative syndrome## (@@ALPS##) is a @@disorder of lymphocyte homeostasis and immunological tolerance##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte homeostasis and immunological tolerance. Output: [/INST] @@Autoimmune lymphoproliferative syndrome## (@@ALPS##) is a @@disorder of lymphocyte homeostasis and immunological tolerance##.

@@Autoimmune lymphoproliferative syndrome## (@@ALPS##) is a @@disorder of lymphocyte homeostasis and immunological tolerance##.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Most patients have a heterozygous mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an apoptotic pathway crucial to lymphocyte homeostasis. Output:

Most patients have a heterozygous mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an apoptotic pathway crucial to lymphocyte homeostasis.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Most patients have a heterozygous mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an apoptotic pathway crucial to lymphocyte homeostasis. Output: [/INST] Most patients have a heterozygous mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an apoptotic pathway crucial to lymphocyte homeostasis.

Most patients have a heterozygous mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an apoptotic pathway crucial to lymphocyte homeostasis.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Of 17 unique APT1 mutations in unrelated ALPS probands, 12 (71%) occurred in exons 7-9, which encode the intracellular portion of Fas. Output:

Of 17 unique APT1 mutations in unrelated @@ALPS## probands, 12 (71%) occurred in exons 7-9, which encode the intracellular portion of Fas.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Of 17 unique APT1 mutations in unrelated ALPS probands, 12 (71%) occurred in exons 7-9, which encode the intracellular portion of Fas. Output: [/INST] Of 17 unique APT1 mutations in unrelated @@ALPS## probands, 12 (71%) occurred in exons 7-9, which encode the intracellular portion of Fas.

Of 17 unique APT1 mutations in unrelated @@ALPS## probands, 12 (71%) occurred in exons 7-9, which encode the intracellular portion of Fas.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In vitro, activated lymphocytes from all 17 patients showed apoptotic defects when exposed to an anti-Fas agonist monoclonal antibody. Output:

In vitro, activated lymphocytes from all 17 patients showed apoptotic defects when exposed to an anti-Fas agonist monoclonal antibody.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In vitro, activated lymphocytes from all 17 patients showed apoptotic defects when exposed to an anti-Fas agonist monoclonal antibody. Output: [/INST] In vitro, activated lymphocytes from all 17 patients showed apoptotic defects when exposed to an anti-Fas agonist monoclonal antibody.

In vitro, activated lymphocytes from all 17 patients showed apoptotic defects when exposed to an anti-Fas agonist monoclonal antibody.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Similar defects were found in a Fas-negative cell line transfected with cDNAs bearing each of the mutations. Output:

Similar defects were found in a Fas-negative cell line transfected with cDNAs bearing each of the mutations.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Similar defects were found in a Fas-negative cell line transfected with cDNAs bearing each of the mutations. Output: [/INST] Similar defects were found in a Fas-negative cell line transfected with cDNAs bearing each of the mutations.

Similar defects were found in a Fas-negative cell line transfected with cDNAs bearing each of the mutations.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In cotransfection experiments, Fas constructs with either intra- or extracellular mutations caused dominant inhibition of apoptosis mediated by wild-type Fas. Output:

In cotransfection experiments, Fas constructs with either intra- or extracellular mutations caused dominant inhibition of apoptosis mediated by wild-type Fas.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: In cotransfection experiments, Fas constructs with either intra- or extracellular mutations caused dominant inhibition of apoptosis mediated by wild-type Fas. Output: [/INST] In cotransfection experiments, Fas constructs with either intra- or extracellular mutations caused dominant inhibition of apoptosis mediated by wild-type Fas.

In cotransfection experiments, Fas constructs with either intra- or extracellular mutations caused dominant inhibition of apoptosis mediated by wild-type Fas.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two missense Fas variants, not restricted to patients with ALPS, were identified. Output:

Two missense Fas variants, not restricted to patients with @@ALPS##, were identified.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Two missense Fas variants, not restricted to patients with ALPS, were identified. Output: [/INST] Two missense Fas variants, not restricted to patients with @@ALPS##, were identified.

Two missense Fas variants, not restricted to patients with @@ALPS##, were identified.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Variant A (-1) T at the Fas signal-sequence cleavage site, which mediates apoptosis less well than wild-type Fas and is partially inhibitory, was present in 13% of African American alleles. Output:

Variant A (-1) T at the Fas signal-sequence cleavage site, which mediates apoptosis less well than wild-type Fas and is partially inhibitory, was present in 13% of African American alleles.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Variant A (-1) T at the Fas signal-sequence cleavage site, which mediates apoptosis less well than wild-type Fas and is partially inhibitory, was present in 13% of African American alleles. Output: [/INST] Variant A (-1) T at the Fas signal-sequence cleavage site, which mediates apoptosis less well than wild-type Fas and is partially inhibitory, was present in 13% of African American alleles.

Variant A (-1) T at the Fas signal-sequence cleavage site, which mediates apoptosis less well than wild-type Fas and is partially inhibitory, was present in 13% of African American alleles.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among the ALPS-associated Fas mutants, dominant inhibition of apoptosis was much more pronounced in mutants affecting the intracellular, versus extracellular, portion of the Fas receptor. Output:

Among the @@ALPS##-associated Fas mutants, dominant inhibition of apoptosis was much more pronounced in mutants affecting the intracellular, versus extracellular, portion of the Fas receptor.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Among the ALPS-associated Fas mutants, dominant inhibition of apoptosis was much more pronounced in mutants affecting the intracellular, versus extracellular, portion of the Fas receptor. Output: [/INST] Among the @@ALPS##-associated Fas mutants, dominant inhibition of apoptosis was much more pronounced in mutants affecting the intracellular, versus extracellular, portion of the Fas receptor.

Among the @@ALPS##-associated Fas mutants, dominant inhibition of apoptosis was much more pronounced in mutants affecting the intracellular, versus extracellular, portion of the Fas receptor.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mutations causing disruption of the intracellular Fas death domain also showed a higher penetrance of ALPS phenotype features in mutation-bearing relatives. Output:

Mutations causing disruption of the intracellular Fas death domain also showed a higher penetrance of @@ALPS## phenotype features in mutation-bearing relatives.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Mutations causing disruption of the intracellular Fas death domain also showed a higher penetrance of ALPS phenotype features in mutation-bearing relatives. Output: [/INST] Mutations causing disruption of the intracellular Fas death domain also showed a higher penetrance of @@ALPS## phenotype features in mutation-bearing relatives.

Mutations causing disruption of the intracellular Fas death domain also showed a higher penetrance of @@ALPS## phenotype features in mutation-bearing relatives.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Significant ALPS-related morbidity occurred in 44% of relatives with intracellular mutations, versus 0% of relatives with extracellular mutations. Output:

Significant @@ALPS##-related morbidity occurred in 44% of relatives with intracellular mutations, versus 0% of relatives with extracellular mutations.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Significant ALPS-related morbidity occurred in 44% of relatives with intracellular mutations, versus 0% of relatives with extracellular mutations. Output: [/INST] Significant @@ALPS##-related morbidity occurred in 44% of relatives with intracellular mutations, versus 0% of relatives with extracellular mutations.

Significant @@ALPS##-related morbidity occurred in 44% of relatives with intracellular mutations, versus 0% of relatives with extracellular mutations.

The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Thus, the location of mutations within APT1 strongly influences the development and the severity of ALPS. Output:

Thus, the location of mutations within APT1 strongly influences the development and the severity of @@ALPS##.

<s> [INST] The task is to label all mentions of diseases in a sentence, by putting them in a specific format.: Identify all the mentions of diseases in the following sentence, by putting @@ in front and a ## behind each of them Input: Thus, the location of mutations within APT1 strongly influences the development and the severity of ALPS. Output: [/INST] Thus, the location of mutations within APT1 strongly influences the development and the severity of @@ALPS##.

Thus, the location of mutations within APT1 strongly influences the development and the severity of @@ALPS##.