Patent Document ID: 8155906
Application ID: 10400158
Patent Status: 1

Claim One:
1. A method of analysis, comprising: A) detecting molecular binding interactions between analytes in a sample and molecular structures immobilized on one or more sensing surface areas of a biosensor; B) producing a plurality of binding response curves to form a resulting set, each response curve representing a binding interaction of an analyte with a molecular structure over time, each response curve comprising an analyte association part and an analyte dissociation part; C) subjecting the resulting set of response curves to a data-processing procedure for assessment of a quality of each of the response curves with respect to a presence of oddities in the response curves, the subjecting operation comprising the substeps of: 1) selecting at least two quality-related parameters for the response curves, each of the parameters defining a quality descriptor; 2) computing for each response curve, values for the quality descriptors, which represent the quality of the response curve; 3) based on the values for the quality descriptors, classifying the response curves by computing for each response curve a quality classification which indicates a deviation of the quality descriptors of the corresponding response curve from the quality descriptors of the other response curves in the resulting set produced in the producing operation; 4) selecting a predetermined number of the response curves having quality classifications corresponding to the largest deviations, and defining the predetermined number of response curves as odd quality response curves; 5) displaying the odd quality response curves to a user of the biosensor for visual inspection thereof to thereby decide if an odd quality response curve should be used in the analysis or be rejected; 6) removing odd quality response curves rejected by the user; 7) repeating steps 3) to 6) until no more of the odd quality curves are rejected; and 8) determining from the remaining response curves at least one of molecular surface concentrations and kinetic parameters.