Patent Document ID: 8526694
Application ID: 13012235
Patent Status: 1

Claim One:
1. An image data subtraction system to enhance visualization of vessels subject to movement, comprising: an image data processor for, automatically identifying temporally corresponding pairs of images comprising a mask image and a contrast enhanced image from first and second image sets respectively and for said corresponding pairs, automatically determining a shift of a contrast enhanced image relative to a mask image to compensate for motion induced image mis-alignment by, determining a plurality of candidate shifts for a plurality of different individual regions of said contrast enhanced image relative to corresponding regions of said mask image to compensate for mis-alignment of said individual regions, applying said candidate shifts to said contrast enhanced image as a whole and determining an optimal shift of said candidate shifts based on effectiveness of shifts of said contrast enhanced image as a whole and automatically shifting a contrast enhanced image relative to a mask image in response to the determined optimal shift and subtracting data representing a mask image of a corresponding pair from a shifted contrast enhanced image of said corresponding pair, to provide a plurality of subtracted images showing enhanced visualization of vessels.