Patent Document ID: 9974475
Application ID: 14755765
Patent Status: 1

Claim One:
1. A method for discriminating between benign and malignant skin lesions, the method comprising the steps of: generating a plurality of spectral reflectance images of a skin lesion at a plurality of angles of illumination and detection using an optical transfer diagnosis (OTD) device without repositioning the OTD device, wherein the OTD device comprises a spectral reflectance meter consisting of a measurement head with a plurality of fixed light-emitting diode (LED) lamps and a plurality of cameras wherein the plurality of LED lamps are configured within the OTD device to provide polar angles between 30 and 45 degrees relative to a central opening in the measurement head and relative azimuth angles between 34 and 145 degrees relative to the central opening in the measurement head and wherein the plurality of cameras are configured within the OTD device to provide polar angles between 0 and 45 degrees relative to the central opening in the measurement head, and relative azimuth angles between 0 and 180 degrees relative to the central opening in the measurement head, wherein the central opening in the measurement head is placed above the skin lesion while the plurality of spectral reflectance images is generated; creating, for each of a plurality of parameters, a spatial distribution map of the skin lesion from the plurality of spectral reflectance images; determining entropy values for each of the spatial distribution maps; determining cross entropy values between pairs of the spatial distribution maps; determining, from the plurality of spectral reflectance images, a plurality of morphology parameter values; calculating, for each of the determined values, a logarithm of that determined value; for each of a plurality of weight values, applying that weight value to a corresponding one of the determined values and calculated values to thereby produce a diagnostic index value; comparing the diagnostic index value to a threshold value to thereby indicate if the skin lesion is a malignant skin lesion.