Patent Document ID: 20160239970
Application ID: 15140745
Patent Status: 0

Claim One:
1. A method for characterizing cell motion, comprising: receiving image data corresponding to a set of images of a cardiomyocyte culture captured at a set of time points; performing a time-domain-based determination of a multi-peak motion signal for a cardiomyocyte subpopulation of the cardiomyocyte culture, across a subset of the set of images; determining a resting signal with an associated reference images for the cardiomyocyte subpopulation, based upon the time domain-based determination of the multi-peak motion signal for the cardiomyocyte subpopulation, across a subset of the set of images, wherein determining the resting signal includes identifying a subset of resting-state images from the set of images, wherein a resting-state image has a high similarity to an immediately adjacent image in the set of images; determining a single-peak motion signal based upon the set of images, the set of time points, and the reference image; and determining values of a set of beating features of the cardiomyocyte subpopulation, based upon at least one of the multi-peak motion signal and the single-peak motion signal, and the set of time points, thereby characterizing cell motion, wherein the set of beating features includes at least one of: a beating duration, a beating frequency, and a beating irregularity.