Patent Document ID: 8669524
Application ID: 12911334
Patent Status: 1

Claim One:
1. A method of generating an image, the method comprising: obtaining images of an area of an object generated using a probe having a probe size greater than or equal to a minimum probe size, wherein obtaining the images comprises configuring the probe with multiple different point spread functions each associated with a respective probe size, wherein the probe is configured with a first point spread function of the multiple different point spread functions, and a first set of images of the obtained images are obtained with the probe having the first point spread function, and the probe is reconfigured with a second point spread function of the multiple different point spread functions, and a second set of images of the obtained images are obtained with the probe having the second point spread function, wherein a point spread function of the multiple different point spread functions is associated with the minimum probe size, and wherein the obtained images comprise one or more convolutions, of a structure of the object within the imaged area of the object, with the multiple point spread functions with which the probe was configured to obtain the images; and generating from the obtained images an enhanced image having a higher resolution than that provided by the point spread function associated with the minimum probe size, the generating comprising determining, based on the obtained images and at least some of the multiple different point spread functions with which the probe was configured and used to obtain images of the multiple images, an emission intensity emitted from a pixel area of the area of the object, the determining deconvoluting at least a portion of the structure of the object corresponding to the pixel area, wherein the generated enhanced image comprises a representation of the emission intensity emitted from the pixel area of the area of the object, the pixel area being smaller than the minimum probe size.