Patent Document ID: 9983282
Application ID: 11944062
Patent Status: 1

Claim One:
1. A method for producing an image of bioelectromagnetic activity in a subject with a magnetic resonance imaging (MRI) system, the steps comprising: a) acquiring T 1ρ -weighted image data from the subject using a pulse sequence that directs the MRI system to perform a spin-lock preparatory pulse sequence prior to acquiring nuclear magnetic resonance (NMR) image data, wherein the spin-lock preparatory pulse sequence includes applying a spin-lock radio frequency (RF) field, B 1ρ , that establishes a spin-lock condition in transverse spin magnetization such that transverse spin magnetization in the spin-lock condition is rotated by bioelectromagnetic fields directly produced by neuronal activity in the subject; b) reconstructing an image with the acquired T 1ρ -weighted image data; and c) analyzing image signals in the T 1ρ -weighted image to detect locations of neuronal activity in the subject.