Patent Document ID: 7979214
Application ID: 11592610
Patent Status: 1

Claim One:
1. A method of finding one or more possible matching peptides to a test peptide associated with a tandem mass spectrometry test spectrum, comprising: with a computer, selecting an objective function ƒ that includes at least one term comprising the number of peaks, η, that appear in both a test spectrum, s 1 and a simulated spectrum of one of a plurality of candidate peptide, s 2 , wherein η indicates the number of peaks in s 1 with corresponding peaks in s 2 and the number of peaks in s 1 that are translated in s 2 ; and performing a genetic algorithm on a plurality of candidate peptides using the obejective function ƒ, wherein the act of performing comprises determining and storing η for s 1 and s 2 .