Patent Document ID: 9937347
Application ID: 14557161
Patent Status: 1

Claim One:
1. An apparatus for controlling patient-specific selective activation of a combination of targeted white matter pathways to treat a neurological condition using deep brain stimulation (DBS), comprising: a first circuit that creates a patient-specific therapeutic tractography map of a patient brain based, at least in part, on a pre-operative medical image of the patient brain and a population-based therapeutic tractography map of the human brain, where the pre-operative medical image of the patient brain is a diffusion tensor magnetic resonance imaging (MRI) image, where the population-based therapeutic tractography map of the human brain is based, at least in part, on activation volume tractography derived from a neural response to a specific electrical stimulation parameter associated with a neurostimulation; a second circuit that identifies one or more desired DBS electrode placements and one or more stimulation parameters for treatment of the neurological condition using DBS based, at least in part, on the patient-specific therapeutic tractography map, where the one or more DBS electrode placements and the one or more stimulation parameters facilitate activation of axons located in the combination of white matter pathways; and a third circuit that selectively modifies the one or more stimulation parameters based, at least in part, on actual locations of the one or more DBS electrodes as determined from a post-operative medical image of the patient brain and on the patient-specific therapeutic tractography map.