Patent Document ID: 9135700
Application ID: 13891301
Patent Status: 1

Claim One:
1. A method for analyzing a digital pathology image comprising: selecting at least one analysis region in the digital pathology image; separating the at least one analysis region into a tissue region and a background region using a predetermined separation threshold; identifying one or more prospective pixels within the tissue region as nuclei pixels based on a predetermined selection function; determining whether at least a predetermined number of pixels surrounding the one or more prospective pixels are also nuclei pixels; selecting the one or more prospective pixels as connected pixels when at least the predetermined number of pixels surrounding the one or more prospective pixels are determined to be nuclei pixels; designating a nucleus region based on a perimeter of the connected pixels; designating a membrane region according to the tissue region and the nuclei nucleus region; refining the membrane region according to at least one predetermined refinement parameter; and generating a membrane intensity score of the refined membrane region according to a predetermined model.