Patent Document ID: 20100312115
Application ID: 12478831
Patent Status: 0

Claim One:
1. A method for continuous non-invasive hemodynamic state monitoring in a subject comprising: acquiring continuous ultrasound data via an ultrasound transducer attached to the subject; estimating a plurality of continuous arterial waveforms based upon the acquired ultrasound data; deriving hemodynamic parameters for each cardiac cycle from the arterial waveforms; defining a current hemodynamic state of the subject by setting limits on one or more hemodynamic parameters based upon the variation of these parameters over an initial period of time; defining an initial biomechanical model of the artery calibrated for the current hemodynamic state that converts arterial waveforms into a continuous estimate of arterial blood pressure; continuously monitoring the hemodynamic state of the subject based upon the generated hemodynamic parameters from subsequent measurements; comparing the current state for one or more hemodynamic parameters of the subject to previously determined limits for one or more hemodynamic parameters, and performing either of the following: outputting a trigger signal or alarm from the hemodynamic state monitor, redefining the current hemodynamic state of the subject by setting new limits for one or more of the hemodynamic parameters based on recent measurements, and calibrating a new biomechanical model for the current hemodynamic state in an event that a change is detected in the current state of one or more hemodynamic parameters; converting the arterial waveforms into a continuous estimate of the arterial blood pressure using the biomechanical model, and outputting the current hemodynamic parameters, blood pressure estimates, and arterial waveforms in an event that a change in the current state of the one or more hemodynamic parameters is not detected.