Patent Document ID: 20150167058
Application ID: 14491996
Patent Status: 0

Claim One:
1. A method for evaluating and/or diagnosing a subject having or suspected of having Alzheimer's disease comprising: a) obtaining a test cell sample from the subject, b) assaying the test cell sample using 3D analysis to determine one or more telomere organization signature of the test sample, the telomere organization signature comprising one or more parameter values selected from: i) telomere aggregates; ii) telomere number; iii) telomere length and telomere number; and iv) telomere aggregates, telomere length and telomere numbers; c) comparing the test cell sample telomere organization signature to one or more predetermined reference signatures, each reference signature comprising a control and/or one or more reference parameter values; and d) evaluating and/or diagnosing whether the subject has AD and/or is likely to develop AD according to the test sample telomere organization signature.