Patent Document ID: 8348428
Application ID: 12740008
Patent Status: 1

Claim One:
1. A method of detecting and characterizing square wave jerks (SWJs) in the eye movements of a person, for the diagnosis of progressive supranuclear palsy (PSP) disease comprising: a) providing an apparatus for obtaining a sequence of saccades and obtaining a sequence of saccades from both eyes of a person; b) identifying via an apparatus pairs of consecutive saccades of the sequence; c) determining via an apparatus whether each saccade of each identified pair is opposite the direction of the other saccade and, if not, then discarding the pair; d) determining via an apparatus whether a magnitude of each saccade of each identified pair is comparable and, if not, then discarding the pair; e) determining via an apparatus whether the pair of saccades of each identified pair are temporally related by a predetermined time period and, if not, then discarding the pair; f) collecting via an apparatus any remaining pairs of saccades as square wave jerks; h) using an apparatus to determine one or more of the following parameters: (A) the number of SWJs per second; (B) the percentage of small saccades that are part of SWJs; (C) the average magnitude of the saccades that are part of SWJs; (D) the number of saccades per second; (E) the average peak velocity of the saccades in SWJs; (F) the standard deviation of the direction difference; and (G) the standard deviation of the difference between the horizontal and direction of the saccades in the SWJs; and h) comparing the one or more determined parameter with the parameter for a healthy person, whereby a statistical difference between the parameters indicates the presence of PSP.