Patent Document ID: 9683939
Application ID: 14709239
Patent Status: 1

Claim One:
1. A system for performing automated high-content cell imaging, the system comprising: a stage assembly configured to receive a container having a plurality of wells containing biological cells and to automatically and selectively position each of the wells at a viewing position, wherein the biological cells have been labeled with one or more fluorophores and one or more chromophores; a fluorophore excitation source that automatedly produces excitation light that is directed to the viewing position to induce fluorophore emission light from the one or more fluorophores labeling the biological cells positioned at the viewing position; a transmission light assembly that automatedly produces transmission light that is directed to the viewing position to induce a chromophore absorption signature from the one or more chromophores labeling the biological cells positioned at the viewing position; a microscope objective aligned with the viewing position to receive the induced fluorophore emission light and the induced chromophore absorption signature; and an imaging device that automatedly and sequentially or concurrently images and records both the induced fluorophore emission light and the induced chromophore absorption signature.