Patent Document ID: 9823163
Application ID: 14878294
Patent Status: 1

Claim One:
1. An optical system configured to predict clinical visual performance of an intraocular lens (IOL), the system comprising: an IOL optical quality measurement device configured to acquire a plurality of images of a target including objects with different spatial frequencies and obtain modulation transfer function (MTF) and/or phase transfer function (PTF) at different spatial frequencies for different defocus positions of the IOL in a vision range from the acquired plurality of images, the measurement device comprising: a processor configured to execute programmable instructions stored in a non-transitory computer storage medium to calculate a metric based on at least one preclinical metric selected from: an area under the MTF (MTFa) obtained by integrating preclinical through focus MTF measurements obtained for different spatial frequencies between 0 cycles per mm and 200 cycles per mm for each of the different defocus positions; a cross correlation coefficient (X-cor) corresponding to a convolution of a reference image and the plurality of images acquired by the IOL optical quality measurement device at each of the different defocus positions; a weighted MTF (wMTF) obtained by integrating a product of a threshold contrast sensitivity (CS th ) and through focus MTF measurements obtained for different spatial frequencies between 0 cycles per mm and 200 cycles per mm for each of the different defocus positions; or a weighted OTF (wOTF) obtained by integrating a product of a threshold contrast sensitivity (CS th ), through focus MTF measurements, and cosine of the PTF obtained for different spatial frequencies between 0 cycles per mm and 200 cycles per mm for each of the different defocus positions; and obtain a correlation between the calculated metric and clinical data that predicts visual acuity (VA) at different defocus positions of the intraocular lens (IOL).