Datasets:
query
stringlengths 1
13.4k
| pos
stringlengths 1
61k
| neg
stringlengths 1
63.9k
| query_lang
stringclasses 147
values | __index_level_0__
int64 0
3.11M
|
|---|---|---|---|---|
Purification and crystallization of NADPH-adrenodoxin reductase from bovine adrenocortical mitochondria | Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes. | False Negatives at Neonatal Adrenal Hyperplasia in Two Deficiency Screening for Siblings with Congenital 21-Hydroxylase | eng_Latn | 0 |
Effect of increases in myocardial epinephrine content on epinephrine release from the dog heart. | Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo | Porin channels in intact cells of Escherichia coli are not affected by Donnan potentials across the outer membrane. | eng_Latn | 1 |
Gene expression profiles in response to the activation of adrenoceptors in A7r5 aortic smooth muscle cells. | Gene expression profiles and signaling mechanisms in α2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells | Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice | eng_Latn | 2 |
Electrophysiological identification of a pathway from the septal area to the medial amygdala: sensitivity to estrogen and luteinizing hormone-releasing hormone. | FDG-PET analysis of amygdalar-cortical network covariance during pre- versus post-menopausal estrogen levels: potential relevance to resting state networks, mood, and cognition. | Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men | eng_Latn | 3 |
DOPAMINERGIC INHIBITION OF PITUITARY β-ENDORPHIN-LIKE IMMUNOREACTIVITY SECRETION IN THE RAT | Central a 2-Adrenergic Stimulation Increases Neurointermediate Lobe Immunoreactive / 3-Endorphin in Spontaneously Hypertensive Rats | Endothelial Dysfunction, Erectile Dysfunction and Phosphodiesterase 5 Inhibitors. An Update of the Current Data and Future Perspectives | yue_Hant | 4 |
To evaluate the effects of altered corticosteroid metabolism on the hypothalamic-pituitary-adrenal axis, we examined rats treated with glycyrrhizic acid (G rats) or rifampicin (R rats) for 7 days. The half-life of exogenously administered hydrocortisone as a substitute for corticosterone was longer in G rats and shorter in R rats, with no differences in basal plasma levels of ACTH or corticosterone. The ACTH responses to human corticotropin-releasing factor (CRF) or insulin-induced hypoglycemia were greater in G rats and tended to be smaller in R rats compared with those in the control rats, whereas the corticosterone response was similar. No difference was observed in the content and mRNA level of hypothalamic CRF among the groups. The number and mRNA level of CRF receptor and type 1 11 beta-hydroxysteroid dehydrogenase (11-HSD1) mRNA level in the pituitary were increased in G rats but not changed in R rats, suggesting that chronically increased intrapituitary corticosterone upregulates pituitary CRF receptor expression. In contrast, CRF mRNA levels in the pituitary were increased in R rats. Our data indicate novel mechanisms of corticosteroid metabolic modulation and the involvement of pituitary 11-HSD1 and CRF in glucocorticoid feedback physiology. | The mechanism regulating pituitary CRH receptors during stress was studied by analysis of the changes in CRH receptor messenger RNA (mRNA) and CRH binding after acute and repeated stress and CRH and vasopressin (VP) administration in intact and adrenalectomized rats. Acute stress caused time- and stress type-dependent changes in pituitary CRH receptor expression. In situ hybridization studies showed biphasic changes in CRH receptor mRNA after immobilization stress for 1 h and decreases by 2 h (P < 0.01). Increases (P < 0.01) were seen 4 and 8 h after the initiation of the stress, and a return to near basal levels by 12 and 18 h. A different pattern, with a decrease by 4 h (P < 0.01) and levels similar to controls after 12 and 18 h, was observed after a single ip injection of hypertonic saline (1.5 M NaCl). Binding autoradiography showed significant increases in pituitary CRH binding 4, 10, and 12 h after immobilization stress, but significant decreases 4, 12, and 18 h after ip hypertonic saline. In contrast, repeated immobilization or ip hypertonic saline for 8 or 14 days increased pituitary CRH receptor mRNA, and CRH binding was decreased. To determine the role of hypothalamic CRH and VP on these stress-induced changes, rats were injected for 14 days with CRH, VP, or their combination at doses mimicking stress levels in pituitary portal circulation (1 microgram/day sc). Repeated injection of CRH or VP increased CRH receptor mRNA and CRH binding (P < 0.05). CRH receptor mRNA levels further increased after combined administration of CRH and VP (P < 0.01), but CRH binding showed a tendency to decrease. The role of glucocorticoids on CRH receptor regulation was studied by analysis of the effects of stress on CRH receptor mRNA and CRH binding in adrenalectomized (ADX) rats with and without corticosterone replacement in the drinking water. Although in 6-day ADX rats pituitary CRH receptor mRNA levels were markedly reduced after acute immobilization, glucocorticoid replacement restored the stimulatory effect of stress to levels observed in intact rats. Similarly, a single sc injection of CRH (1 microgram) decreased CRH receptor mRNA in ADX rats but not in glucocorticoid-replaced ADX rats. CRH binding showed the expected decrease after ADX and was unchanged after stress or CRH injection. The increased pituitary CRH receptor mRNA after stress suggests that stress-induced CRH receptor down-regulation is due to increased receptor occupancy and internalization rather than to a decrease in receptor synthesis. The data suggest that increased hypothalamic secretion of CRH and VP mediates the delayed up-regulatory effect of stress on CRH receptor mRNA, and that resting levels of glucocorticoids are required for this effect. In addition, increased VP levels are permissive for the down-regulation of CRH binding induced by chronic pituitary exposure to stress levels of CRH. | Women are twice as likely as men to suffer from stress-related psychiatric disorders, like unipolar depression and post-traumatic stress disorder. Although the underlying neural mechanisms are not well characterized, the pivotal role of stress in the onset and severity of these diseases has led to the idea that sex differences in stress responses account for this sex bias. Corticotropin-releasing factor (CRF) orchestrates stress responses by acting both as a neurohormone to initiate the hypothalamic–pituitary–adrenal (HPA) axis and as a neuromodulator in the brain. One target of CRF modulation is the locus coeruleus (LC)–norepinephrine system, which coordinates arousal components of the stress response. Hypersecretion of CRF and dysregulation of targets downstream from CRF, such as the HPA axis and LC–norepinephrine system, are characteristic features of many stress-related psychiatric diseases, suggesting a causal role for CRF and its targets in the development of these disorders. This review will describe sex differences in CRF and the LC–norepinephrine system that can increase stress sensitivity in females, making them vulnerable to stress-related disorders. Evidence for gonadal hormone regulation of hypothalamic CRF is discussed as an effect that can lead to increased HPA axis activity in females. Sex differences in the structure of LC neurons that create the potential for hyperarousal in response to emotional stimuli are described. Finally, sex differences at the molecular level of the CRF1 receptor that make the LC–norepinephrine system more reactive in females are reviewed. The implications of these sex differences for the treatment of stress-related psychiatric disorders also will be discussed. | eng_Latn | 5 |
An understanding of the regulation of CRF secretion in rats is currently incomplete, in part due to the lack of sensitive in vitro models available for studying this neuropeptide. In particular, the effects of catecholamines on CRF secretion, and the receptor subtypes mediating these actions have long been the subject of much debate. A cultured cell model has been adapted for studying secretory responses of hypothalamic cells of 1-week-old rats. Between 7–16 days in monolayer culture the cells secreted detectable levels of immunoreactive CRF, and this release was paralleled by the appearance of punctate bead-like regions of immunoreactivity along fine cellular processes. CRF secretion was increased up to 4-fold by norepinephrine (EC50, -0.5 μM). The increase in CRF secretion produced by norepinephrine was blocked by the β-receptor antagonist propranolol, but not by the α-antagonist prazosin. Moreover, the β-receptor agonist isoproterenol significantly elevated CRF secretion, whereas the α-agonist phenylep... | The changes in the content of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in discrete brain nuclei during chronic opioids administration have not been well established. We evaluated the effects of acute and chronic morphine administration on the content of CRF and AVP in different hypothalamic and extrahypothalamic (bed nucleus of the stria terminalis, BNST) nuclei in rats. Concomitantly, changes in hypothalamic noradrenaline (NA) turnover [estimated by the 3-methoxy-4-hydroxyphenylethyleneglycol MHPG/NA ratio] and in plasma corticosterone release (as a marker of the activity of the hypothalamus-pituitary-adrenal axis) were determined. Male rats were implanted with placebo (naïve) or morphine (tolerant) pellets for 7 days. On day 8, groups of rats received an acute injection of either saline i.p. or morphine (30 mg/kg i.p.) and were sacrificed 30 min later. Acute morphine injection to naïve rats increased both the release of corticosterone and the hypothalamic NA turnover. CRF and AVP showed no modifications in the paraventricular nucleus (PVN) or in the median eminence (ME). CRF content decreased in the ventromedian nucleus (VMN) and increased in the BNST, but did not change in the arcuate nucleus (AN). AVP was elevated in the supraoptic nucleus (SON) but not changed in the suprachiasmatic nucleus (SCN). In chronic morphine-treated rats, there was a pronounced decrease in the NA turnover and in the release of corticosterone, which indicates that tolerance develops to the acute effects of morphine. Correspondingly, CRF and AVP were enhanced in the PVN and decreased in the ME, when compared with naïve rats injected with morphine. CRF content was decreased in the AN and in the BNST, but increased in the VMN. The AVP content was decreased in the SON, and no modifications were seen in the SCN. The present study shows that, in addition to the modifications in corticosterone secretion and in hypothalamic NA turnover, chronic morphine administration produces a complex response in the CRF and AVP systems. These modifications might contribute to the behavioral, emotional and neuroendocrine alterations produced during opioid tolerance. | Women are twice as likely as men to suffer from stress-related psychiatric disorders, like unipolar depression and post-traumatic stress disorder. Although the underlying neural mechanisms are not well characterized, the pivotal role of stress in the onset and severity of these diseases has led to the idea that sex differences in stress responses account for this sex bias. Corticotropin-releasing factor (CRF) orchestrates stress responses by acting both as a neurohormone to initiate the hypothalamic–pituitary–adrenal (HPA) axis and as a neuromodulator in the brain. One target of CRF modulation is the locus coeruleus (LC)–norepinephrine system, which coordinates arousal components of the stress response. Hypersecretion of CRF and dysregulation of targets downstream from CRF, such as the HPA axis and LC–norepinephrine system, are characteristic features of many stress-related psychiatric diseases, suggesting a causal role for CRF and its targets in the development of these disorders. This review will describe sex differences in CRF and the LC–norepinephrine system that can increase stress sensitivity in females, making them vulnerable to stress-related disorders. Evidence for gonadal hormone regulation of hypothalamic CRF is discussed as an effect that can lead to increased HPA axis activity in females. Sex differences in the structure of LC neurons that create the potential for hyperarousal in response to emotional stimuli are described. Finally, sex differences at the molecular level of the CRF1 receptor that make the LC–norepinephrine system more reactive in females are reviewed. The implications of these sex differences for the treatment of stress-related psychiatric disorders also will be discussed. | eng_Latn | 6 |
The proopiocortin (adrenocorticotropin/beta-lipoprotein) gene is located on chromosome 2 in humans. | 1 Role of Opioidergic System in Humoral Immune Response | Lipoproteins containing the truncated apolipoprotein, Apo B-89, are cleared from human plasma more rapidly than Apo B-100-containing lipoproteins in vivo. | eng_Latn | 7 |
Differences Between Exclusive Breastfeeders, Formula-Feeders, and Controls: A Study of Stress, Mood, and Endocrine Variables | Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. | Found : long-term gains from early intervention | eng_Latn | 8 |
Glucocorticoid secretion is tightly regulated by negative feedback. Glucocorticoid feedback has been found to be altered in depression and post-traumatic stress disorder (PTSD). While hyposensitive glucocorticoid feedback has been found in depression, hypersensitive or enhanced negative feedback was described in PTSD. Enhanced negative feedback, can be seen as a sensitization of the inhibitory elements of HPA axis, and stress-restress or time dependent sensitization (TDS) model, has been suggested as an animal model for PTSD. We have studied the effects of this model on the HPA axis to determine whether it will produce increased sensitivity to negative feedback as found in PTSD patients. Adult Sprague-Dawley male rats were exposed to a single session of prolonged stress (restraint followed by a forced swim and exposure to ether vapors) and briefly restressed 7 days later. The effects of single prolonged stress on plasma ACTH and corticosterone responses (0, 5, and 30 min) and on glucocorticoid fast feedback (cortisol vs. saline pretreatment) were assessed in two studies. Animals exposed to single prolonged stress showed enhanced negative feedback in comparison to naive animals (F = 4.6371, df = 3, p = .0107), but there was no difference in ACTH or corticosterone responses during the restress. Pretreatment with cortisol, in the first stress session, did not prevent the development of the enhanced fast feedback when restressed. This can be seen as a sensitization of the inhibitory elements of HPA axis, suggesting that stress-restress paradigm might serve as a good animal model for HPA abnormalities found in PTSD patients. | Background Posttraumatic stress disorder (PTSD) is a severe, persistent psychiatric disorder in response to a traumatic event, causing intense anxiety and fear. These responses may increase over time upon conditioning with fear-associated cues, a phenomenon termed fear incubation. Corticotropin-releasing factor receptor type 1 (CRFR1) is involved in activation of the central stress response, while corticotropin-releasing factor receptor type 2 (CRFR2) has been suggested to mediate termination of this response. Corticotropin-releasing factor (CRF) receptors are found in stress-related regions, including the bed nucleus of stria terminalis (BNST), which is implicated in sustained fear. Methods Fear-related behaviors were analyzed in rats exposed to predator-associated cues, a model of psychological trauma, over 10weeks. Rats were classified as susceptible (PTSD-like) or resilient. Expression levels of CRF receptors were measured in the amygdala nuclei and BNST of the two groups. In addition, lentiviruses overexpressing CRFR2 were injected into the medial division, posterointermediate part of the BNST (BSTMPI) of susceptible and resilient rats and response to stress cues was measured. Results We found that exposure to stress and stress-associated cues induced a progressive increase in fear response of susceptible rats. The behavioral manifestations of these rats were correlated both with sustained elevation in CRFR1 expression and long-term downregulation in CRFR2 expression in the BSTMPI. Intra-BSTMPI injection of CRFR2 overexpressing lentiviruses attenuated behavioral impairments of susceptible rats. Conclusions These results implicate the BNST CRF receptors in the mechanism of coping with stress. Our findings suggest increase of CRFR2 levels as a new approach for understanding stress-related atypical psychiatric syndromes such as PTSD. | ABSTRACTUNC-45A is an ubiquitously expressed protein highly conserved throughout evolution. Most of what we currently know about UNC-45A pertains to its role as a regulator of the actomyosin system... | eng_Latn | 9 |
The effects of trilostane, a 3β-hydroxysteroid dehydrogenase inhibitor on basal cortisol concentrations and the results of acth stimulation tests in dogs with pituitary-dependent hyperadrenocorticism were investigated. In eight of nine dogs trilostane suppressed the concentration of cortisol below the lower limit of the reference range ( | Cushing’s disease caused by pituitary corticotroph adenoma is a common endocrine disease in dogs. A characteristic biochemical feature of corticotroph adenomas is their relative resistance to suppressive negative feedback by glucocorticoids. The abnormal expression of 11beta-hydroxysteroid dehydrogenase (11HSD), which is a cortisol metabolic enzyme, is found in human and murine corticotroph adenomas. Our recent studies demonstrated that canine corticotroph adenomas also have abnormal expression of 11HSD. 11HSD has two isoforms in dogs, 11HSD type1 (HSD11B1), which converts cortisone into active cortisol, and 11HSD type2 (HSD11B2), which converts cortisol into inactive cortisone. It has been suggested that glucocorticoid resistance in corticotroph tumors is related to the overexpression of HSD11B2. Therefore it was our aim to investigate the effects of carbenoxolone (CBX), an 11HSD inhibitor, on the healthy dog’s pituitary-adrenal axis. Dogs were administered 50 mg/kg of CBX twice each day for 15 days. During CBX administration, no adverse effects were observed in any dogs. The plasma adrenocorticotropic hormone (ACTH), and serum cortisol and cortisone concentrations were significantly lower at day 7 and 15 following corticotropin releasing hormone stimulation. After completion of CBX administration, the HSD11B1 mRNA expression was higher, and HSD11B2 mRNA expression was significantly lower in the pituitaries. Moreover, proopiomelanocortin mRNA expression was lower, and the ratio of ACTH-positive cells in the anterior pituitary was also significantly lower after CBX treatment. In adrenal glands treated with CBX, HSD11B1 and HSD11B2 mRNA expression were both lower compared to normal canine adrenal glands. The results of this study suggested that CBX inhibits ACTH secretion from pituitary due to altered 11HSD expressions, and is potentially useful for the treatment of canine Cushing’s disease. | A 49-year-old woman with traumatic brain injury after an automobile accident is found to have raised intracranial pressure, and hyperosmolar therapy is recommended. Hyperosmolar therapy with either hypertonic saline or mannitol reduces intracranial pressure by reducing brain volume. | eng_Latn | 10 |
Four patients with Cushing's syndrome and variable cyclic hormonogenesis are reported and 40 other cases from the literature are reviewed. These cases were divided into four categories depending on regular or irregular cyclic adrenal hypersecretion and presence or absence of concomitant fluctuations in the clinical course. The manifestations of cyclic adrenal hypersecretion in these patients varied from daily to yearly intervals. Cyclic activity persisted for as long as 25 years, with cycle lengths varying from 12 hours to 85 days. Some patients demonstrated complex biochemical cyclic patterns. Clinical presentations varied from a single outstanding symptom, such as recurring oedema, to a complex clinical syndrome. The aetiology in these patients varied: 12 appeared to be pituitary dependent, 11 had corticotropin-producing tumours and another eight were described as showing 'adrenal hyperplasia'. A hypothalamic disorder was found in four, a benign adrenal adenoma in two, and an adrenal 'mass' and adrenocortical nodular dysplasia in single patients. Evaluation during the intercyclic phase may reveal normal pituitary function. Inconsistent responsiveness to administration of dexamethasone in different phases of cyclic activities may suggest the presence of cyclic Cushing's syndrome. | Cyclic Cushing's syndrome (CS) is a rare disorder, characterized by repeated episodes of cortisol excess interspersed by periods of normal cortisol secretion. The so-called cycles of hypercortisolism can occur regularly or irregularly with intercyclic phases ranging from days to years. To formally diagnose cyclic CS, three peaks and two troughs of cortisol production should be demonstrated. Our review of 65 reported cases demonstrates that cyclic CS originates in 54% of cases from a pituitary corticotroph adenoma, in 26% from an ectopic ACTH-producing tumour and in about 11% from an adrenal tumour, the remainder being unclassified. The pathophysiology of cyclic CS is largely unknown. The majority of patients with cyclic CS have clinical signs of CS, which can be either fluctuating or permanent. In a minority of patients, clinical signs of CS are absent. The fluctuating clinical picture and discrepant biochemical findings make cyclic CS extremely hard to diagnose. Clinicians should therefore be aware of this clinical entity and actively search for it in all patients with suspected CS but normal biochemistry or vice versa. Frequent measurements of urinary cortisol or salivary cortisol levels are a reliable and convenient screening tool for suspected cyclic CS. Cortisol stimulation or suppression tests may give spurious results owing to spontaneous falls or rises in serum cortisol at the time of testing. When cyclic CS is biochemically confirmed, further imaging and laboratory studies are guided by the presence or absence of ACTH dependency. In cases of suspected ectopic ACTH production, specific biochemical testing for carcinoids or neuroendocrine tumours is required, including measurements of serotonin in platelets and/or urine, chromogranin A and calcitonin. | In this short note we prove that if X is a separably rationally connected variety over an algebraically closed field of positive characteristic, then H^1(X, O_X)=0. | eng_Latn | 11 |
Estrogen receptor- mediates acute myocardial protection in females | Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice | 5-HT3 receptor ligands lack modulatory influence on acetycholine release in rat entorhinal cortex | eng_Latn | 12 |
In the human body, the adrenal glands are directly above which organ? | Adrenal glands - RightDiagnosis.com Adrenal glands Article Excerpts about Adrenal glands Cortisol is normally produced by the adrenal glands, located just above the kidneys. It belongs to a class of hormones called glucocorticoids, which affect almost every organ and tissue in the body. Scientists think that cortisol has possibly hundreds of effects in the body. Cortisol's most important job is to help the body respond to stress. Among its other vital tasks, cortisol: helps maintain blood pressure and cardiovascular function; helps slow the immune system's inflammatory response; helps balance the effects of insulin in breaking down sugar for energy; and helps regulate the metabolism of proteins, carbohydrates, and fats. Because cortisol is so vital to health, the amount of cortisol produced by the adrenals is precisely balanced. Like many other hormones, cortisol is regulated by the brain's hypothalamus and the pituitary gland, a bean-sized organ at the base of the brain. (Source: excerpt from Addison's Disease: NIDDK ) Summary Information: Adrenal glands Adrenal glands: The adrenal glands are a pair of endocrine glands, one located on the top of each kidney. The adrenal glands produce a variety of hormones, chemical substances that help to regulate a wide variety of the body's processes. The adrenal glands and the hormones they produce play a big role in such processes as metabolism, water and electrolyte balance, sexual development and function, the immune system, and the stress response. The adrenal glands include two regions, the adrenal cortex and the adrenal medulla, which each produce different hormones. Adrenal hormones include the catecholamines epinephrine and norepinephrine, and the adrenal steroid hormones: adrenal androgen hormones, mineralocorticoids, and glucocorticoids. Conditions that can afflict the adrenal glands include Addison's disease, Cushing's syndrome, pheochromocytoma, hyperaldosteronism, adrenal tumors, adrenal cancer, and trauma. Closely Related Organs: Adrenal glands The following organs are closely related to the organ: Adrenal glands: | Les parties du corps - Des os, il en faut - alain le lait (French body parts) - YouTube Les parties du corps - Des os, il en faut - alain le lait (French body parts) Want to watch this again later? Sign in to add this video to a playlist. Need to report the video? Sign in to report inappropriate content. Rating is available when the video has been rented. This feature is not available right now. Please try again later. Uploaded on Oct 30, 2011 Des os, il en faut - alain le lait du CD 'Parapluie' ©2006 Une chanson sur les parties du corps Words and english translation Tu as deux mains et deux pieds Tu as deux jambes et un nez Tu as un ventre et un dos Et des muscles sous la peau Tu as une tête et un cou Deux oreilles et deux genoux Tu as deux yeux et deux joues Et une bouche qui mange tout, et Sous ta peau il y a des os Des petits et des gros Des os, des os, il en faut C'est parce que tu as des os que ... Bones, you must have them You have two hands and two feet You have two legs and a nose You have a belly (stomach) and a back And muscles underneath your skin You have a head and a neck Two ears and two knees You have two eyes and two cheeks And a mouth that eats everything and Under your skin you have bones Small bones and big ones Bones, bones, you must have them It's because you have bones that ... (repeat from top of the song) Category | eng_Latn | 13 |
Which has specific control sympathetic or parasympathetic? | Group the autonomic nervous system sympathtic and parasympathetic division which one is normally in control or has more specific control? | Group the autonomic nervous system sympathtic and parasympathetic division which one is normally in control or has more specific control? | eng_Latn | 14 |
Which gland secretes the corticosteroids? | Adrenal Glands | Johns Hopkins Medicine Health Library Adrenal Glands: What You Need to Know Adrenal glands, also known as suprarenal glands, are small, triangular-shaped glands located on top of both kidneys. Adrenal glands produce hormones that help regulate your metabolism, immune system, blood pressure, response to stress and other essential functions. Adrenal glands are composed of two parts — the cortex and the medulla — which are each responsible for producing different hormones. When adrenal glands don’t produce enough hormones, this can lead to adrenal insufficiency (Addison’s disease). Adrenal glands may develop nodules that can be benign or malignant. These nodules may produce excessive amounts of certain hormones leading to various health issues. Anatomy of the Adrenal Glands An adrenal gland is made of two main parts: The adrenal cortex is the outer region and also the largest part of an adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. The adrenal medulla is located inside the adrenal cortex in the center of an adrenal gland. It produces several “stress hormones,” including adrenaline. The adrenal cortex and adrenal medulla are enveloped in an adipose capsule that forms a protective layer around an adrenal gland. Hormones of the Adrenal Glands The role of the adrenal glands in your body is to release certain hormones directly into the bloodstream. Many of these hormones have to do with how the body responds to stress, and some are vital to existence. Both parts of the adrenal glands — the adrenal cortex and the adrenal medulla — perform distinct and separate functions. Each zone of the adrenal cortex secretes a specific hormone. The key hormones produced by the adrenal cortex include: Cortisol Cortisol is a glucocorticoid hormone produced by the zona fasciculata that plays several important roles in the body. It helps control the body’s use of fats, proteins and carbohydrates; suppresses inflammation; regulates blood pressure; increases blood sugar; and can also decrease bone formation. This hormone also controls the sleep/wake cycle. It is released during times of stress to help your body get an energy boost and better handle an emergency situation. How Adrenal Glands Work to Produce Cortisol Adrenal glands produce hormones in response to signals from the hypothalamus and the pituitary gland in the brain. For example, for the adrenal gland to produce cortisol: The hypothalamus produces corticotropin-releasing hormone (CRH) that stimulates the pituitary gland to secrete adrenocorticotropin hormone (ACTH). The ACTH then stimulates the adrenal glands to make and release cortisol hormones into the blood. Normally, both the hypothalamus and the pituitary gland can sense whether the blood has the right amount of cortisol in it. If there is too much or too little cortisol, these glands respectively change the amount of CRH and ACTH that gets released. Excess cortisol production can occur from nodules in the adrenal gland or excess production of ACTH from a tumor in the pituitary gland or other source. Aldosterone This mineralocorticoid hormone produced by the zona glomerulosa plays a central role in regulating blood pressure and certain electrolytes (sodium and potassium). Aldosterone sends signals to the kidneys, resulting in the kidneys absorbing more sodium into the bloodstream and releasing potassium into the urine. This means that aldosterone also helps regulate the blood pH by controlling the levels of electrolytes in the blood. DHEA and Androgenic Steroids These hormones produced by the zona reticularis are weak male hormones. They are precursor hormones that are converted in the ovaries into female hormones (estrogens) and in the testes into male hormones (androgens). However, estrogens and androgens are produced in much larger amounts by the ovaries and testes. Epinephrine (Adrenaline) and Norepinephrine (Noradrenaline) The adrenal medulla, the inner part of an adrenal gland, controls | babble: Mordechai Vanunu elected as Glasgow University Rector posted 16 December 2004 04:23 PM That seems like a good point. I never understood why one would want to keep deterrence a secret. Try to invade the Israelis and they will vaporize your capital city... Kind of guarantees they'll leave the Israelis alone. Makes the region safer, doesn't it? Or maybe not. What seems logical to me is often upside down and sideways in the Middle East. Too much sun? The French have written dozens of books on how the Gaullists and the Socialists gave the Israelis the bomb. Is the Pope Catholic? I don't get it about this controversy. [ 16 December 2004: Message edited by: Critical Mass ] From: King & Bay (downtown Toronto) - I am King of the World!!! | Registered: Jun 2004 | IP: Logged lagatta | eng_Latn | 15 |
The hormone which is responsible for fearangerpainLove and Rate of heart beat? | What in music makes your heart beat faster? | Is not George Bush responsible for Iraq desturction? | eng_Latn | 16 |
What affect does secrete have on the body? | What affect does secrete adrenaline have on the body? | What affect does secrete adrenaline have on the body? | eng_Latn | 17 |
The eccrine sweat glands are distributed over much of the body . | First , let 's concentrate on how sweat is made in an eccrine sweat gland . | Bullets are affected by gravity , and weapons are highly inaccurate when fired `` from the hip '' . | eng_Latn | 18 |
Diagnose Adrenal Disease in Ferrets | The adrenal glands are small glands that have important functions in a ferret’s body. Located near the kidneys, the adrenal glands produce and secrete various substances, including sex hormones (estrogen, testosterone, progesterone) and cortisol (‘stress hormone’), that control different functions in a ferret’s body. | If you're reading this, congratulations on being a caring pet owner. You recognize the need to give your small pet proper healthcare; an important aspect of providing a healthy and happy life. | eng_Latn | 19 |
Know the Various Controlling Systems of the Body | The main controlling systems of the body are the nervous system and the endocrine system. These systems will be discussed in the context of this article in addition to other important functions. | This wikiHow teaches you how to use the Command Prompt app to open your Windows computer's Control Panel. | eng_Latn | 20 |
Which body part is producing the adrenaline? And can you feel it happening? | The Adrenal glands which are located above the kidney. You cant feel it because it is a hormone being released. All you would feel is "fight or flight" feelings.\nYou should get yourself checked because it could be something else. | dont worry that's not you, exactly. it's a demon named sexazel. he lives inside you. if you wanna get rid of him find a NY hooker named esmeralda. she's not really a hooker but an exorcist. hope this helps | eng_Latn | 21 |
How does the human body know when to cry, and why do we do it when we are sad/happpy? | It is a response tiggered by emotions configured in past experiences.\nCrying is a more complicated process than one would at first imagine. First of all, there are really three different types of tears. Basal tears keep our eyes lubricated constantly. Reflex tears are produced when our eyes get irritated, like with onions or when something gets into our eyes. The third kind of tear is produced when the body reacts emotionally to something. Each type of tear contains different amounts of chemical proteins and hormones. Scientists have discovered that the emotional tears contain higher levels of manganese and the hormone prolactin, and this contributes in a reduction of both of these in the body; thus helping to keep depression away. Many people have found that crying actually calms them after being upset, and this is in part due to the chemicals and hormones that are released in the tears. \n\nHow then actually do we cry? The psychic tears (or emotional tears) require an emotional response, or trigger to be activated. This response can be caused by an outside source, either pain or loss of love, etc., or from an inside source (self-realization of one's life and others). When emotions affect us, the nervous system stimulates the cranial nerve, in the brain and this sends signals to the neurotransmitters to the tear glands. Thus, we cry .The largest tear gland, the lacrimal gland produces the tears of emotion and reflex. Many believe that the body, in times of emotional stress, depends on this gland to release excess amounts of chemicals and hormones, returning it to a stable state. | Okay, if you find an answer to this, can you please email me? I really need one, too. Sorry if you saw this and got all excited, thinking it was an answer. Really, I am! ):^( \nemail- ktviscosi@yahoo.com | eng_Latn | 22 |
What would happen to you physically if your adrenal glands stopped working? | It would be life threatening. Look up Addison's Disease on the internet | Rent yourself out to movies as a stand-in for tigers for when the stunt is too dangerous and they need someone else to do it. | eng_Latn | 23 |
Is sympathetic activity considered a feedforward mechanism?? | Hormonal activity is usually a negative feed back mechanism. You would think exercise would feed forward, though, as the rate would keep increasing. Not my area, though, so a functional biologist is needed here. | yuk,I am stimulated by a non bloody penis or tongue and I refuse to wear those pamper type of object that requires my pritty_pussykat to sit in blood for any length of time and fail to imagine any thing stimulating about the experience or thought of it | eng_Latn | 24 |
how does heart rate change when something scary happens? | Adrenaline is released into the blood stream. Another name for Adrenaline is Epinephrine.\n\nEpinephrine plays a central role in the short-term stress reaction—the physiological response to threatening or exciting conditions. It is secreted by the adrenal medulla. When released into the bloodstream, epinephrine binds to multiple receptors and has numerous effects throughout the body. It increases heart rate and stroke volume, dilates the pupils, and constricts arterioles in the skin and gut while dilating arterioles in leg muscles. It elevates the blood sugar level by increasing hydrolysis of glycogen to glucose in the liver, and at the same time begins the breakdown of lipids in fat cells. | Because if you could just watch mine every day, you would know why...\nLoses keys, wallet, checkbook, glasses, backpack, money... | eng_Latn | 25 |
Assessment of the hypothalamic-pituitary-adrenal axis over a 24-hour diurnal period and in response to neuroendocrine challenges in women with and without childhood sexual abuse and posttraumatic stress disorder. | Dose-response changes in plasma cortisol and lymphocyte glucocorticoid receptors following dexamethasone administration in combat veterans with and without posttraumatic stress disorder. | Fully Printed Halide Perovskite Light-Emitting Diodes with Silver Nanowire Electrodes | eng_Latn | 26 |
what is pheochromocytoma adrenal gland | A pheochromocytoma is an adrenal gland tumor that secretes epinephrine and norepinephrine hormones. These hormones are responsible for regulating heart rate and blood pressure, among other functions. Pheochromocytomas occur most frequently in young to middle-aged adults between the ages of 30 and 60. Ten percent of individuals affected are children who usually develop symptoms between the ages of 6 and 14. | A pheochromocytoma is a tumor that most commonly occurs within special cells of the adrenal gland called chromaffin cells. This type of tumor produces too many hormones called catecholamines, which include adrenaline. | eng_Latn | 27 |
what hormone is released when your stressed | This hormone is released by the hypothalamus and eventually leads to the release of cortisol. So the pill blocks the entire stress pathway starting at the top. The pill is likely to be extremely important in treating depression associated with severe stress. | Cortisol (hydrocortisone) is a steroid hormone produced in the adrenal glands. Itâs released in response to stress and low levels of glucose (our numero uno source of body energy â a simple sugar). Cortisol is often referred to as the stress hormone. | eng_Latn | 28 |
vasopressin is the same hormone as | Vasopressin, also known as arginine vasopressin (AVP), antidiuretic hormone (ADH), or argipressin, is a neurohypophysial hormone found in most mammals.Its two primary functions are to retain water in the body and to constrict blood vessels. It is likely that vasopressin acts in conjunction with corticotropin-releasing hormone to modulate the release of corticosteroids from the adrenal gland in response to stress, particularly during pregnancy and lactation in mammals. | Vasopressin (Antidiuretic Hormone). Vasopressin (arginine vasopressin, AVP; antidiuretic hormone, ADH) is a peptide hormone formed in the hypothalamus, then transported via axons to, and released from, the posterior pituitary into the blood. AVP has two principle sites of action: the kidney and blood vessels.1 The primary function of AVP in the body is to regulate extracellular fluid volume by affecting renal handling of water, although it is also a vasoconstrictor and pressor agent (hence, the name vasopressin).VP has two principle sites of action: the kidney and blood vessels. 1 The primary function of AVP in the body is to regulate extracellular fluid volume by affecting renal handling of water, although it is also a vasoconstrictor and pressor agent (hence, the name vasopressin). | eng_Latn | 29 |
what is ad lib in medical terms | Medical Definition of Ad lib. Ad lib: Abbreviation for the Latin ad libitum meaning at pleasure and at one's pleasure, as much as one desires, to the full extent of one's wishes.. Sometimes seen on a prescription or doctor's order. | Vasopressin, also known as arginine vasopressin (AVP), antidiuretic hormone (ADH), or argipressin, is a neurohypophysial hormone found in most mammals. Its two primary functions are to retain water in the body and to constrict blood vessels.asopressin regulates the body's retention of water by acting to increase water reabsorption in the kidney's collecting ducts, the tubules which receive the very dilute urine produced by the functional unit of the kidney, the nephrons. | eng_Latn | 30 |
what chemical is released during the fight or flight due to stress | What are the signs that our fight or flight response has been stimulated (activated)? When our fight or flight response is activated, sequences of nerve cell firing occur and chemicals like adrenaline, noradrenaline and cortisol are released into our bloodstream. These patterns of nerve cell firing and chemical release cause our body to undergo a series of very dramatic changes. | Cortisol is commonly referred to as the stress hormone .. The hormone is secreted by the adrenal glands and released into the bloodstream as a fight or flight response to stress. The highest quantities of cortisol are produced in the early morning hours and then production slowly tapers off throughout the day. | eng_Latn | 31 |
where is atrial natriuretic hormone secreted from | Atrial natriuretic peptide (ANP) is a hormone, produced mainly by cardiomyocytes, with a major role in cardiovascular homeostatic mechanisms such as natriuresis and vasodilation, which serve to regulate blood pressure. | Chr 4: 148 â 148 Mb. PubMed search. Atrial natriuretic peptide (ANP), also called atrial natriuretic factor (ANF), atrial natriuretic hormone (ANH), cardionatrine, cardiodilatin (CDD), or atriopeptin, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. | eng_Latn | 32 |
similarity and difference between nervous system and endocrine system | What are the similarities between the nervous system and the endocrine system? Both the nervous system and endocrine system are devoted to maintaining homeostasis by coordinating and regulating the activities of other cells, tissues, organs, and systems. Both systems are regulated by negative feedback mechanisms. Chemical messengers are important in both systems, although their method of transmission and release differs in the two systems. | Key Differences. The nervous system is made of neuron cells while the Endocrine System is made of glands. Transmission is performed by the electrochemical pulses in nervous system. On the contrary, the Chemicals known as hormones are responsible for signal transmission in Endocrine System. | eng_Latn | 33 |
what is an adrenal mass? | An adrenal tumor or adrenal mass is any benign or malignant neoplasms of the adrenal gland, several of which are notable for their tendency to overproduce endocrine hormones. | The adrenal glands are composed of two heterogenous types of tissue. In the center is the adrenal medulla, which produces adrenaline and noradrenaline and releases them into the bloodstream, as part of the sympathetic nervous system. Surrounding the medulla is the cortex, which produces a variety of steroid hormones. | eng_Latn | 34 |
what causes overproduction of cortisol | Cushing's syndrome is the result of excessive corticosteroids in the body. The main cause is overproduction of adrenocorticotropin hormone (ACTH) in the pituitary gland.ACTH causes the adrenal glands to produce corticosteroids, so too much of ACTH means too much of corticosteroids.ushing's syndrome is the result of excessive corticosteroids in the body. The main cause is overproduction of adrenocorticotropin hormone (ACTH) in the pituitary gland. | Basically cortisol causes depression. Cortisol is a stress hormone, and it has always been obvious to clinicians that stress can make one more susceptible to a multitude of disorders. Also, patients with major depression have higher levels of cortisol. | eng_Latn | 35 |
what is the effect of norepinephrine on systemic arterioles | Septic shock is often complicated by systemic hypotension despite normal or increased cardiac output. Restoration of arterial pressure usually requires the administration of systemic vasopressor agents, such as norepinephrine. However, because norepinephrine induces vasoconstriction in other vascular beds, it may decrease visceral blood flow, impairing visceral organ function. | norepinephrine (NE). [norâ²nôrâ²epinef]. rin an adrenergic (hormone) catecholamine that acts to increase blood pressure by vasoconstriction but does not affect cardiac. Output it is synthesized by the adrenal, medulla the peripheral sympathetic, nerves and the central nervous. system | eng_Latn | 36 |
what is a cortice | cortex. the outer layer of an organ or other structure, as distinguished from its inner substance or medulla. adj., adj cor´tical. adrenal cortex (cortex of adrenal gland) the outer, firm layer comprising the larger part of the adrenal gland; it secretes mineralocorticoids, androgens, and glucocorticoids. | Cortisone is a type of medication that treats a wide variety of conditions, mainly by suppressing inflammation. Often referred to as corticosteroids, cortisone drugs belong to a class of medication known as glucocorticoids. Doctors may prescribe cortisone to prevent allergic reactions and to treat arthritis, ulcerative colitis, skin problems such as psoriasis and acne, lupus, eye conditions, and some cancers. | eng_Latn | 37 |
what is histamines | Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine is involved in the inflammatory response and has a central role as a mediator of pruritus.ost histamine in the body is generated in granules in mast cells and in white blood cells called basophils and eosinophils. Mast cells are especially numerous at sites of potential injury â the nose, mouth, and feet, internal body surfaces, and blood vessels. | Histamine is an important neurotransmitter and immune messenger molecule. It is involved in processes involving hydrochloric acid secretion for digestion, triaging water reserves to key areas of the body and the inflammatory response (1). One of the major effects of histamine is causing the blood vessels to swell and dilate. When the body senses that it is threatened it will secrete higher amounts of histamine. This allows the white blood cells to quickly move through the blood stream and find the potential threat or infection. | eng_Latn | 38 |
what are sarms | The term SARMS stands for âSelective Androgen Receptor Modulators .â Androgens are a class of hormones that serve as ligands that bind to cellular androgen receptors. The androgen receptor is involved in a complex signal transduction pathway that ultimately results in greater expression of specific genes. | The term SARMS stands for âSelective Androgen Receptor Modulators .â Androgens are a class of hormones that serve as ligands that bind to cellular androgen receptors. The androgen receptor is involved in a complex signal transduction pathway that ultimately results in greater expression of specific genes. | eng_Latn | 39 |
what do adrenal hormones do | The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions.ach gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces a class of steroid hormones called corticosteroids, named according to their effects. | The adrenal cortex secretes corticosteroids and other hormones directly into the bloodstream. The hormones produced by the adrenal cortex include: Cortisol. This hormone helps control the body's use of fats, proteins, and carbohydrates.he adrenal medulla, the inner part of the adrenal gland, helps a person cope with physical and emotional stress. The adrenal medulla secretes the following hormones: Epinephrine (also called adrenaline) . | eng_Latn | 40 |
what does an internal stimulus do | In physiology, a stimulus (plural stimuli) is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity.When a stimulus is applied to a sensory receptor, it normally elicits or influences a reflex via stimulus transduction.ne internal stimulus that causes hormone release is blood pressure. Hypotension, or low blood pressure, is a large driving force for the release of vasopressin, a hormone which causes the retention of water in the kidneys. | The internal thermoregulation process is one aspect of homeostasis: a state of dynamic stability in an organism's internal conditions, maintained far from equilibrium with its environment (the study of such processes in zoology has been called physiological or physiological ecology).he internal thermoregulation process is one aspect of homeostasis: a state of dynamic stability in an organism's internal conditions, maintained far from equilibrium with its environment (the study of such processes in zoology has been called physiological or physiological ecology). | eng_Latn | 41 |
what is an adrenergic fiber | adrenergic fibers. 1. nerve fiber's that transmit nervous impulses to other nerve cells (or smooth muscle or gland cells) by the medium of the adrenalinelike transmitter substance norepinephrine (noradrenaline). | Adrenergic nervous system, a part of autonomic nervous system that uses epinephrine or norepinephrine as its neurotransmitter Regarding proteins: Adrenergic receptor | eng_Latn | 42 |
what chemicals trigger stress | 1 The US Food and Drug Administration (FDA) has warned that the drugs Lexiscan and Adenoscan, used in cardiac chemical stress tests may trigger fatal heart attacks. 2 Recent deaths have been reported to the FDA Adverse Event Reporting System and the medical literature related to the drugs. | The negative effects of stress. When you perceive a crisisâ-or think a stressful thoughtâ-your brain secretes corticotrophin-releasing hormone (CRH). This master stress hormone triggers the release of glucocorticoid stress hormones, such as cortisol. Stimulated by glucocorticoids and other stress hormones (like adrenaline), the brain and body shift into crisis mode. Your breathing and pulse quicken, making more oxygen available to your muscles. | eng_Latn | 43 |
what is catecholamines used for | Catecholamines are released into the blood when a person is under physical or emotional stress. The main catecholamines are dopamine, norepinephrine, and epinephrine (which used to be called adrenalin). This test is used to diagnose or rule out certain rare tumors, such as pheochromocytoma or neuroblastoma. | Furthermore, catecholamines are not only released from nerve terminals and the adrenal medulla, but can also be actively produced, stored, and secreted by immune cells themselves [16]. Catecholamines released from immune cells serve as auto/paracrine regulators of lymphocyte activity, for example | eng_Latn | 44 |
what gland process potassium | Sodium and potassium are both regulated by the adrenal glands. So weakened adrenal glands can cause an imbalance in the sodium and potassium levels. Aldosterone is a steroid hormone which helps to regulate the levels of these minerals. This hormone helps to preserve the sodium levels, and secretes potassium.n this situation, taking potassium without sodium can actually make the adrenal condition worse. While the adrenals help to regulate the sodium and potassium levels, imbalances in these minerals can also affect the adrenals, and thus directly or indirectly affect thyroid health. | (See also Overview of Adrenal Function.) Aldosterone is the most potent mineralocorticoid produced by the adrenals. It causes sodium retention and potassium loss. In the kidneys, aldosterone causes transfer of sodium from the lumen of the distal tubule into the tubular cells in exchange for potassium and hydrogen. | eng_Latn | 45 |
what is aldosterone levels | An aldosterone test measures the level of aldosterone (a hormone made by the adrenal glands), in the blood. Aldosterone helps regulate sodium and potassium levels in the body. This helps control blood pressure and the balance of fluids and electrolytes in the blood. The kidney hormone renin normally stimulates the adrenal glands to release aldosterone. | Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland. | eng_Latn | 46 |
aldosterone definition | Aldosterone: A hormone produced by the outer portion (cortex) of the adrenal gland. Aldosterone regulates the balance of water and electrolytes in the body, encouraging the kidney to excrete potassium into the urine and retain sodium, thereby retaining water. | You won't believe these 10 facts about people. Aldosterone is a mineralocorticoid hormone that is essential to life because it regulates the amounts of electrolytes in the body. It's secreted by the adrenal cortex, part of the adrenal gland, and is responsible for the reabsorption of sodium into the bloodstream.ldosterone is a mineralocorticoid hormone that is essential to life because it regulates the amounts of electrolytes in the body. | eng_Latn | 47 |
how does cushings disease differ from addisons disease | Cushing's disease---also known as Cushing's syndrome---and Addison's disease occur when your adrenal glands do not produce proper amounts of a hormone called cortisol. | Overview. Addisonâs disease occurs when the adrenal cortex is damaged and the adrenal glands do not produce enough steroid hormones called cortisol and aldosterone. Cortisol regulates the bodyâs reaction to stressful situations. | eng_Latn | 48 |
what does cortisol in blood do | Cortisol is one of the steroid hormones and is made in the adrenal glands. Most cells within the body have cortisol receptors. Secretion of the hormone is controlled by the hypothalamus, the pituitary gland, and the adrenal gland, a combination glands often referred to as the HPA axis. What does cortisol do? Because most bodily cells have cortisol receptors, it affects many different functions in the body. Cortisol can help control blood sugar levels, regulate metabolism, help reduce inflammation, and assist with memory formulation. It has a controlling effect on salt and water balance and helps control blood pressure. | A serum cortisol test may help in the diagnosis of two fairly uncommon medical conditions: Cushing's syndrome and Addison's disease. The test also screens for other diseases that affect your pituitary and adrenal glands. It does so by measuring your blood level of a stress hormone called cortisol.Cortisol is a steroid hormone made by your adrenal glands. It helps your body respond to stress, regulate blood sugar, and fight infections.In most people, cortisol levels are highest in the morning when they wake up and lowest around midnight.he test also screens for other diseases that affect your pituitary and adrenal glands. It does so by measuring your blood level of a stress hormone called cortisol. Cortisol is a steroid hormone made by your adrenal glands. It helps your body respond to stress, regulate blood sugar, and fight infections. | eng_Latn | 49 |
noradrenaline is also called | Norepinephrine, also called noradrenaline, substance that is released predominantly from the ends of sympathetic nerve fibres and that acts to increase the force of skeletal muscle contraction and the rate and force of contraction of the heart. | Norepinephrine is also released in the sympathetic nervous system, causing the fight-or-flight response around the body. Norepinephrine is also a hormone which is released into the bloodstream by adrenal medulla.As a drug, it increases blood pressure.orepinephrine (NE) , or noradrenaline, is found in the central and autonomic nervous systems. Its adjective is noradrenergic. | eng_Latn | 50 |
what gland secretes epinephrine | At the center of the adrenal glands we see the adrenal medulla. This portion of the gland is stimulated by the sympathetic nervous system to secrete catecholamines, which are hormones that help you deal with short-term stress. There are two catecholamines. One is called epinephrine or adrenaline. | Epinephrine is produced continuously in small amounts by the adrenal glands, but when the body is threatened in times of excitement, danger, or emotional stress, the brain sends messages to the adrenal glands, which respond by increasing epinephrine production.pinephrine, also known as adrenaline, is a hormone secreted by the medulla (inner part) of the adrenal glands, located on the kidneys. The adrenal glands are one of the body's endocrine glands (glands producing substances that are distributed by way of the bloodstream). | eng_Latn | 51 |
where does stress come from? | From where does our stress originate? If you were to ask 10 people where their stress comes from, you will very likely get an array of answers like, their children, family, work, finances, etc. These are stress factors that are common to most of us. But, when you get answers like these, and try to dig around a bit to understand them, you will often find that while all of these things can contribute to our stress, they are not where the stress actually comes from. | Stress causes the body to release the hormone cortisol, which is produced by the adrenal glands. Cortisol is important to blood pressure regulation and the normal functioning of several body systems including cardiovascular, circulatory and male reproduction. | eng_Latn | 52 |
one of the functions of aldosterone hormone is | Aldosterone is both responsible for absorption of sodium and excretion of potassium. If it is regulated by the level of potassium in blood, then we have negative feedback as high levels of aldosterone causes a decrease in potassium level in blood. If it is regulated by the level of sodium in bloodâ¦. | This makes good biological sense: 1 The main function of aldosterone is to maintain normal sodium levels in the body. 2 An increased sensitivity to sodium in its food would help an animal suffering from sodium deficiency (often a problem for ungulates, like cattle and deer). | eng_Latn | 53 |
what organs are adrenal glands near | The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces a class of steroid hormones called corticosteroids, named according to their effects. Mineralocorticoids, produced in the zona glomerulosa, help in the regulation of blood pressure and electrolyte balance. | The adrenal glands are small, walnut-sized glands located above the kidneys. Their job is to release hormones to respond to stress. While some of us may physically handle stress better than others, many of us are all-too-familiar with exhausted and overworked adrenal glands that function far below optimal levels.he adrenal glands are small, walnut-sized glands located above the kidneys. Their job is to release hormones to respond to stress. While some of us may physically handle stress better than others, many of us are all-too-familiar with exhausted and overworked adrenal glands that function far below optimal levels. | eng_Latn | 54 |
what do your adrenal glands do | The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.They are found above the kidneys and consist of a series of layers with different structure and functions.he adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. | Adrenal gland. The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions.he adrenal medulla is at the centre of each adrenal gland, and is surrounded by the adrenal cortex. The chromaffin cells of the medulla are the body's main source of the catecholamines adrenaline and noradrenaline, released by the medulla. | eng_Latn | 55 |
what does your sympathetic nervous system do in a crisis? | In a crisis, the sympathetic division of your autonomic nervous system (ANS) mobilizes your body for action, directing your adrenal glands to release the stress hormone epinephrine (adrenaline) and norepinephrine (noradrenaline). To provide energy, your liver pours extra sugar into your bloodstream. | sympathetic nervous system. initiates the involuntary responses of a full-body reaction to stimuli, such as an acceleration of heart rate, respiratory rate, and blood pressure, as well as a corresponding deceleration of digestive function. | eng_Latn | 56 |
what is the role of adh in water reabsorption? | Aldosterone and antidiuretic hormone work together to maintain blood pressure and fluid levels in the blood. Aldosterone is responsible for maintaining solute levels in the blood and indirectly, water levels in the blood and blood pressure. | What hormone is necessary for water to be reabsorbed in the kidney? The hormone that controls the reabsorbtion of water by the kidneys? the hormone is called Anti-Diuretic Hormone (ADH) it is release by the pitutary gland in the brain and is responsible for the maintenence of water levels. | eng_Latn | 57 |
what is cushing's triad | Cushing's triad, which includes bradycardia, hypertension (with widened pulse pressure), and a change in respiratory pattern, is seen in head injuries with increased intracranial pressure (ICP). | Also known as Pituitary Pars Intermedia Dysfunction or PPID, Cushingâs Disease is a dysfunction of the pituitary gland. It is most common in older horses (18 â 23 years). Since it is sometimes associated with Insulin Resistance, Cushingâs can be confused with another condition called Equine Metabolic Syndrome. | eng_Latn | 58 |
what does the corticosteroid hormone do | Corticosteroids mimic the effects of hormones your body produces naturally in your adrenal glands, which sit on top of your kidneys. When prescribed in doses that exceed your body's usual levels, corticosteroids suppress inflammation.This can reduce the signs and symptoms of inflammatory conditions, such as arthritis and asthma.hen prescribed in doses that exceed your body's usual levels, corticosteroids suppress inflammation. This can reduce the signs and symptoms of inflammatory conditions, such as arthritis and asthma. | Cortisone (/ËkÉrtɨsoÊn/ or /ËkÉrtɨzoÊn/ ; 17-hydroxy-11-dehydrocorticosterone) is a 21-carbon steroid hormone. It is one of the main hormones released by the adrenal gland in response to stress.ortisone, a glucocorticoid, and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response. | eng_Latn | 59 |
which system carries chemical messages to the blood | Hormones | Back to Top. The endocrine system is a collection of glands that secrete chemical messages we call hormones. These signals are passed through the blood to arrive at a target organ, which has cells possessing the appropriate receptor. | Like other nerves, those of the autonomic nervous system convey their messages to the appropriate end organs (blood vessels, viscera, etc.) by releasing transmitter substances to which the receptors of the target cells are responsive. | eng_Latn | 60 |
what are the actions of ephedrine | Mechanism of Action. Ephedrine is a sympathomimetic amine - that is, its principal mechanism of action relies on its direct and indirect actions on the adrenergic receptor system, which is part of the sympathetic nervous system. | 1 Anti-asthmatic [i] - Ephedrine, being a sympathomimetic, is able to cause release of epinephrine and nor-epinephrine, as well as result in relaxation of bronchial smooth muscle. 2 Stimulation of Beta receptors, among other effects, leads to relaxation of bronchial smooth muscle. | eng_Latn | 61 |
how epinephrine increases glucose | Effect of epinephrine on glucose metabolism in humans: contribution of the liver. Abstract. Epinephrine causes a prompt increase in blood glucose concentration in the postabsorptive state. This effect is mediated by a transient increase in hepatic glucose production and an inhibition of glucose disposal by insulin-dependent tissues. Epinephrine augments hepatic glucose production by stimulating glycogenolysis and gluconeogenesis. | The β-adrenergic receptor spans the plasma membrane. The intracellular portion of the receptor is bound to a member of the G-protein class of proteins. In the absence of epinephrine, the G-protein is bound by GDP and is inactive, but binding of the hormone to its receptor induces the exchange of GDP for GTP.Stimulation of glucose production by epinephrine. Through a series of steps, this activates an enzyme located in the plasma membrane called adenylate cyclase.he intracellular portion of the receptor is bound to a member of the G-protein class of proteins. In the absence of epinephrine, the G-protein is bound by GDP and is inactive, but binding of the hormone to its receptor induces the exchange of GDP for GTP. | eng_Latn | 62 |
when you are faced with stressful situations, cortisol, epinephrine, and norepinephrine are released by your | 1: When you are faced with stressful situations, cortisol, epinephrine, and norepinephrine are released by your. kidneys. | Those are both caused by the release of norepinephrine in your body. Norepinephrine is a chemical released from the sympathetic nervous system in response to stress. It is classified as a neurotransmitter, a chemical that is released from neurons.Because the release of norepinephrine affects other organs of the body, it is also referred to as a stress hormone.orepinephrine is a chemical released from the sympathetic nervous system in response to stress. It is classified as a neurotransmitter, a chemical that is released from neurons. | eng_Latn | 63 |
addison's disease | Addison's disease. Addisonâs disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones. Symptoms generally come on slowly and may include abdominal pain, weakness, and weight loss. | From Wikipedia, the free encyclopedia. Addisonâs disease (also Addison disease, chronic adrenal insufficiency, hypocortisolism, and hypoadrenalism) is a rare, chronic endocrine system disorder in which the adrenal glands do not produce sufficient steroid hormones (glucocorticoids and mineralocorticoids).utoimmune adrenalitis is the most common cause of Addison's disease in the industrialised world. Autoimmune destruction of the adrenal cortex is caused by an immune reaction against the enzyme 21-hydroxylase (a phenomenon first described in 1992). | eng_Latn | 64 |
what is pregnenolone steal | The pregnenolone steal is a name given to the hormone production deficit of certain hormones when the stress hormones, cortisol and cortisone, are over-produced. All our hormones come from cholesterol, which converts into pregnenolone as the first step.f the body demands more cortisol because of stress, the body will convert more of the pregnenolone to cortisol at the expense of the other hormones (except progesterone, which is on the pathway to cortisol). The lowering of the testosterone and estrogen leg is called pregnenolone steal. | If the body demands more cortisol because of stress, the body will convert more of the pregnenolone to cortisol at the expense of the other hormones (except progesterone, which is on the pathway to cortisol). The lowering of the testosterone and estrogen levels is called pregnenolone steal.f the body demands more cortisol because of stress, the body will convert more of the pregnenolone to cortisol at the expense of the other hormones (except progesterone, which is on the pathway to cortisol). The lowering of the testosterone and estrogen levels is called pregnenolone steal. | eng_Latn | 65 |
what are chromaffin | chromaffin cell. A cell that produces, stores, and secretes catecholamines (dopamine and norepinephrine). Chromaffin cells are found in the medulla of the adrenal glands and in small clusters in the sympathetic ganglia. | chromaffin cell. A cell that produces, stores, and secretes catecholamines (dopamine and norepinephrine). Chromaffin cells are found in the medulla of the adrenal glands and in small clusters in the sympathetic ganglia. | eng_Latn | 66 |
what is norepinephrine and depression | Norepinephrine and Depression. Norepinephrine and Depression. Norepinephrine functions both a neurotransmitter and hormone in the body. It is classified as a catecholamine hormone which is significant in the body's fight or flee response.hese depression symptoms caused by low level norepinephrine may be treated. There are medications available to counter the effects of low level norepinephrine in the body and treat the depression symptoms associated with it. | Norepinephrine Epinephrine. Norepinephrine, also known as noradrenaline, is a neurotransmitter found in the sympathetic nervous system. The sympathetic nervous system stimulates the heart, blood vessels, sweat glands, the large internal organs, and the adrenal medulla in the brain.he amino acid tyrosine, found in high concentrations in cheese, is converted by specific reactions into at least two neurotransmitters â norepinephrine and dopamine. Norepinephrine is produced from dopamine, with the help of the amino acids phenylalanine, lysine, and methionine. | eng_Latn | 67 |
is melatonin a cortisol antagonist | Cortisol and melatonin are agonists, and fight for dominance. Cortisol is a stress hormone made by the adrenal gland and melatonin is an antioxidant sleep hormone produced by the pineal gland at night, in darkness. | Mifepristone is a cortisol receptor antagonist sometimes used in the treatment of elevated levels of cortisol due to ectopic adrenocorticotrophin (ACTH)-producing tumors. Mifepristone competitively binds glucocorticoid receptors and suppresses the peripheral features of hypercortisolism in Cushing's syndromes. | eng_Latn | 68 |
effects of stress in body organs | 1 Nearly everyone experiences stress at some time. Stress produces changes in many body systems; examples include increased heart rate and blood pressure and altered immune function. Some amount of stress is healthy, but excessive stress, left untreated, can lead to anxiety and illness. | You already know stress can have a number of unpleasant effects, like headaches, weight gain, acne and other skin issues â and it can also affect your period. When you're under physical or emotional stress, your body produces the stress hormones adrenaline and cortisol. | eng_Latn | 69 |
what are the precipitating factors for addison's disease in dogs | In Addison's disease, the adrenal glands don't make enough of a hormone called cortisol, or less often, a related hormone called aldosterone. That's why doctors sometimes call the illness ''chronic adrenal insufficiency,'' or hypocortisolism. | (Also Called 'Chronic Adrenal Insufficiency'). Addisonâs disease is a disorder in which the adrenal glands--which sit on top of the kidneys--do not produce enough of the hormones cortisol and aldosterone. (Hormones are chemicals that control the function of tissues or organs.).ther causes of Addisonâs disease include: 1 injury to the adrenal glands. 2 infection, including tuberculosis, HIV/AIDS-related infections, and fungal infections. 3 cancer cells from another part of the body that have invaded the adrenal glands. 4 bleeding into the adrenal glands. 5 surgical removal of the adrenal glands. | eng_Latn | 70 |
difference between epinephrine and dopamine | Epinephrine and norepinephrine are the hormones underlying the bodyâs âfight or flightâ response, or the changes that occur to a person's physiological state when he or she deals with stressful situations. | Dopamine, norepinephrine and epinephrine are a group of neurotransmitters called catecholamines. Norepinephrine is also called noradrenalin and epinephrine is also called adrenalin. Each of these neurotransmitters is produced in a step-by-step fashion by a different enzyme.eurotransmitters then cross the synapse where they may be accepted by the next neuron at a specialized site called a receptor. The action that follows activation of a receptor site may be either depolarization (an excitatory postsynaptic potential) or hyperpolarization (an inhibitory postsynaptic potential). | eng_Latn | 71 |
what is an epipen | An EpiPen® is an autoinjector which delivers a carefully metered dose of epinephrine intramuscularly via a spring-loaded needle. This device is designed to be used in the emergency treatment of severe allergic reactions. | Epinephrine is a hormone and a neurotransmitter that's also known as adrenaline. As an injectable medicine, such as EpiPen, epinephrine is used to treat life-threatening allergic reactions (anaphylaxis) caused by foods, insect bites, and other allergens.pinephrine is a hormone and a neurotransmitter that's also known as adrenaline. As an injectable medicine, such as EpiPen, epinephrine is used to treat life-threatening allergic reactions (anaphylaxis) caused by foods, insect bites, and other allergens. | eng_Latn | 72 |
what is epinephrine an antidote for | Summary Adrenaline (epinephrine) is a natural hormone released in response to stress. It is a natural antidote to the chemicals released during severe allergic reactions triggered by drug allergy, food allergy or insect allergy. | anecdote / antidote. An anecdote is a funny little story; an antidote counteracts poison. Tell someone an anecdote about your close encounter with a rattlesnake and how the cute park ranger had to get you the antidote for snake venom right away. Continue reading... | eng_Latn | 73 |
what does norepinephrine do for the brain | In the most basic terms, the function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in what has been called the fight-or-flight response.n the sympathetic nervous system norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen, and is also released directly into the bloodstream by the adrenal glands. | Norepinephrine increases. blood flow to the vital organs, such as the brain, increased mental. alertness, enlarged airways, and increased breathing rate. In other words, it helps the body cope with emergency and stress situations. c. Cortisol. Cortisol is one of the glucocorticoids produced by the adrenal cortex. | eng_Latn | 74 |
what hormone is known as the cuddle chemical? | Widely referred to as the love hormone, oxytocin has also been dubbed the hug hormone, cuddle chemical, moral molecule, and the bliss hormone due to its effects on behavior, including its role in love and in female reproductive biological functions in reproduction. | Cushing's syndrome is a relatively rare endocrine (hormonal) disorder resulting from excessive exposure to the hormone cortisol. The disorder, which leads to a variety of symptoms and physical abnormalities, is most commonly caused by taking medications containing the hormone over a long period of time. | eng_Latn | 75 |
epinephrine is part of what kind of signaling? | Epinephrine is an important cell signaling molecule in the fight or flight response. Also known as adrenaline, epinephrine is an efficient messenger that signals many cell types throughout the body with many effects. In the lungs, epinephrine binds to receptors on smooth muscle cells wrapped around the bronchioles.his increases the rate at which other chemical signals, glucose and oxygen are circulated to the cells that need them. Epinephrine also contracts specific types of muscle cells below the surface of the skin, causing beads of perspiration and raised hairs at the surface. | Epinephrine acts by binding to a variety of adrenergic receptors. Epinephrine is a nonselective agonist of all adrenergic receptors, including the major subtypes α 1, α 2, β 1, β 2, and β 3. Epinephrine's binding to these receptors triggers a number of metabolic changes. | eng_Latn | 76 |
adrenal definition | Adrenal gland: A small gland located on top of the kidney. The adrenal glands produce hormones that help control heart rate, blood pressure, the way the body uses food, the levels of minerals such as sodium and potassium in the blood, and other functions particularly involved in stress reactions.he adrenal glands produce hormones that help control heart rate, blood pressure, the way the body uses food, the levels of minerals such as sodium and potassium in the blood, and other functions particularly involved in stress reactions. | The adrenals are two glands, each of which is perched on the upper part of the two kidneys. The outer part of the gland is known as the cortex; the inner part is known as the medulla. Each of these parts of the adrenal gland is responsible for producing different types of hormones. | eng_Latn | 77 |
what are chromaffin cells of adrenal medulla | Within the adrenal medulla are chromaffin cells, which are homologous to sympathetic neurons and, like sympathetic neurons, are developed from embryonic neural crest cells. Chromaffin cells produce epinephrine (adrenaline) and, to... | Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test. Pheochromocytoma is a rare, though potentially lethal, tumor of chromaffin cells of the adrenal medulla that produces episodes of hypertension with palpitations, severe headaches, and sweating (spells). Patients with pheochromocytoma may also be asymptomatic and present with sustained hypertension or an incidentally discovered adrenal mass. | eng_Latn | 78 |
what is addison's disease in humans | Addisonâs disease is a severe or total deficiency of the hormones made in the adrenal cortex, caused by its destruction.There are normally two adrenal glands, located one above each kidney. The adrenal glands are really two endocrine (ductless or hormone producing) glands in one.ortisol production is regulated by another hormone, adrenocorticotrophic hormone (ACTH), made in the pituitary gland which is located just below the brain. Classical Addisonâs disease results from a loss of both cortisol and aldosterone secretion due to the near total or total destruction of both adrenal glands. | Addisonâs disease, the common term for primary adrenal insufficiency, occurs when the adrenal glands are damaged and cannot produce enough of the adrenal hormone cortisol. The adrenal hormone aldosterone may also be lacking. Addisonâs disease affects 110 to 144 of every 1 million people in developed countries. | eng_Latn | 79 |
where is aldosterone secreted | The aldosterone hormone is a hormone produced by the adrenal gland. The hormone acts mainly in the functional unit of the kidneys to aid in the conservation of sodium, secretion of potassium, water retention and to stabilize blood pressure. | Aldosterone is a steroid hormone which is secreted from the zona glomerulosa of the adrenal gland. It has a mineralocorticoid activity and is the most important regulator of plasma potassium. When plasma potassium increases, increased stimulation of aldosterone occurs directly and also as a result of the Renin-Angiotensin-Aldosterone System (RAAS). | eng_Latn | 80 |
what is dhea cream | DHEA creams are a DHEA supplement applied to and absorbed by the skin.They provide DHEA, pregnenolone, and natural progesterone and women use it for bio-identical hormone replacement.HEA creams are also available for men and offers the same benefits. Remember that DHEA is a precursor to both testosterone and estrogen. 1 D-35 Complex For Men by Sarati-a body gel containing DHEA, Progesterone, Pregnenolone, and Chrysin. 2 Twist 25. | DHEA. DHEA is a natural steroid that has been studied for its use in treating several mental health conditions, including mood disorder and PTSD. DHEA (5-Dehydroepiandrosterone) is a natural steroid produced in the adrenal glands, the gonads and the brain. It is the most abundant circulating steroid in humans.A form of DHEA, 7-keto DHEA (3-acetyl-7-oxodehydroepiandosterone), is claimed to have fewer side effects.HEA. DHEA is a natural steroid that has been studied for its use in treating several mental health conditions, including mood disorder and PTSD. DHEA (5-Dehydroepiandrosterone) is a natural steroid produced in the adrenal glands, the gonads and the brain. It is the most abundant circulating steroid in humans. | eng_Latn | 81 |
what is pheochromocytoma | What is a pheochromocytoma. Pheochromocytoma is a part of the pheochromocytoma and paraganglioma group of syndromes. A pheochromocytoma is a tumor arising in the adrenal gland medulla.A paraganglioma grows in the sympathetic or parasympathetic nerves. pheochromocytoma is a functional catecholamine-secreting tumor of the adrenal gland medulla. Catecholamines include epinephrine, norepinephrine and their derivatives. In normal amounts these hormones are responsible for regulating heart rate and blood pressure, among other functions. | A pheochromocytoma is a tumor that usually arises in the adrenal medulla and the patient presents with signs and symptoms of excessive production of catecholamines. pheochromocytoma is a tumor that usually arises in the adrenal medulla and the patient presents with signs and symptoms of excessive production of catecholamines. | eng_Latn | 82 |
where are endorphins found | Endorphins can be found in the pituitary gland, in other parts of the brain, or distributed throughout the nervous system. Stress and pain are the two most common factors leading to the release of endorphins.Endorphins interact with the opiate receptors in the brain to reduce our perception of pain and act similarly to drugs such as morphine and codeine.In contrast to the opiate drugs, however, activation of the opiate receptors by the body's endorphins does not lead to addiction or dependence.ndorphins are among the brain chemicals known as neurotransmitters, which function to transmit electrical signals within the nervous system. At least 20 types of endorphins have been demonstrated in humans. | Herbs. Endorphins are natural opium-like hormones that are produced by the pituitary gland and the hypothalamus of your body. Endorphins act on your brain's opiate receptors to block their ability to receive pain messages from the sensory nerves. | eng_Latn | 83 |
cortisol definition and example | The above are just some examples that demonstrate the interdependency of the adrenal glands with other systems and organs of the body. This is just the beginning. A seemingly infinite amount could be written about the vast influences of cortisol and DHEA on human health. | Cortisol is a steroid hormone made in the adrenal glands. Cortisol's important function in the body includes roles in the regulation of blood pressure and cardiovascular function as well as regulation of the body's use of proteins, carbohydrates, and fats.tress is the sum total of all mental and physical input over a given period of time. The marker used to measure stress is the adrenal steroid hormone, cortisol. Stress, whether physical or emotional in origin, provokes a response by the adrenal glands. | eng_Latn | 84 |
adrenergic response definition | adrenergic receptors. Definition: reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibers of the sympathetic nervous system. | An Adrenergic antagonist is a pharmaceutical substance that acts to inhibit the action of catecholamines at the adrenergic receptors.It is thus a type of sympatholytic. Many important and commonly prescribed medications are adrenergic antagonists, including prazosin and propanolol.n Adrenergic antagonist is a pharmaceutical substance that acts to inhibit the action of catecholamines at the adrenergic receptors. | eng_Latn | 85 |
what does an epinephrine injection do | Epinephrine injection is used to treat life-threatening allergic reactions caused by insect bites, foods, medications, latex, and other causes. Symptoms of allergic reaction include wheezing, shortness of breath, low blood pressure, hives, itching, swelling, stomach cramps, diarrhea, and loss of bladder control.se epinephrine injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. To use the automatic injection device, follow these steps: 1 Hold the device firmly in your fist with the black tip pointing down. | Adrenalin (epinephrine) is a chemical that narrows blood vessels and opens airways in the lungs. These effects can reverse severe low blood pressure, wheezing, severe skin itching, hives, and other symptoms of an allergic reaction. | eng_Latn | 86 |
what happens when a tumor secretes catecholamines | 1 Pheochromocytomas secrete catecholamine hormones (adrenaline and related hormones) that are responsible for the characteristic symptoms. 2 Headache, sweating, and a fast heartbeat are typical symptoms, usually in association with markedly high blood pressure. About 10% of pheochromocytomas are malignant. | Pheochromocytomas secrete catecholamine hormones (adrenaline and related hormones) that are responsible for the characteristic symptoms. Headache, sweating, and a fast heartbeat are typical symptoms, usually in association with markedly high blood pressure. | eng_Latn | 87 |
what is the function of the inner medulla in the adrenal glands | The adrenal glands, located on the top of each kidney, are responsible for releasing different classes of hormones. The outer part of the gland, called the adrenal cortex, produces the hormones cortisol (pronounced KAWR-tuh-sohl) and aldosterone (pronounced al-DOS-tuh-rohn). The inner part of the gland, called the adrenal medulla (pronounced muh-DUHL-uh), produces the hormones adrenaline and noradrenaline. | The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces a class of steroid hormones called corticosteroids, named according to their effects. Mineralocorticoids, produced in the zona glomerulosa, help in the regulation of blood pressure and electrolyte balance. | eng_Latn | 88 |
what is an EPO | epo is a naturally occurring hormone produced by cells in the kidneys that regulate the production of red blood cells in bone marrow these kidney cells are sensitive to low blood oxygen content and will release epo when oxygen is low | Erythropoietin (EPO) is a hormone produced by the kidneys that stimulates red blood cell formation and controls the rate of the formation through negative feedback. | eng_Latn | 89 |
psychological effects of cushing's syndrome | Elevated levels of cortisol exert negative feedback on the pituitary, which decreases the amount of ACTH released from the pituitary gland. Strictly, Cushing's syndrome refers to excess cortisol of any etiology. One of the causes of Cushing's syndrome is a cortisol secreting adenoma in the cortex of the adrenal gland. The adenoma causes cortisol levels in the blood to be very high, and negative feedback on the pituitary from the high cortisol levels causes ACTH levels to be very low. Cushing's disease refers only to hypercortisolism secondary to excess production of ACTH from a corticotrophic pituitary adenoma. | Symptoms of Cushing's syndrome. The pattern of symptoms in Cushing's syndrome can be highly unpredictable. In some cases, the symptoms can develop quickly and be very severe. In other cases, the symptoms can develop gradually and be much milder. Weight gain and fat deposits. | eng_Latn | 90 |
what are cortisol levels | A cortisol test is done to measure the level of the hormone cortisol in the blood. The cortisol level may show problems with the adrenal glands or pituitary gland.Cortisol is made by the adrenal glands. Cortisol levels go up when the pituitary gland releases another hormone called adrenocorticotropic hormone (ACTH).Cortisol has many functions.he cortisol level may show problems with the adrenal glands or pituitary gland. Cortisol is made by the adrenal glands. Cortisol levels go up when the pituitary gland releases another hormone called adrenocorticotropic hormone (ACTH). Cortisol has many functions. | A cortisol test measures the level of the hormone cortisol in a 24-hour sample of urine. The cortisol level may show problems with the adrenal glands or the pituitary gland. Cortisol is made by the adrenal glands. Cortisol levels get higher when the pituitary gland releases adrenocorticotropic hormone (ACTH). | eng_Latn | 91 |
what is causing my adrenal rushes and brain fog | Adrenaline is one of the body's most important stress chemicals. It is secreted from the adrenal glands, which sit atop each kidney. Adrenaline also plays a key role as a neurotransmitter that facilitates communication between brain cells, or neurons, and other cells. An adrenaline rush is a sudden increased secretion of adrenaline from the adrenal glands. It causes an increase in heart rate and respiration. Adrenaline rushes can be healthy responses to actual threats to a person's well-being or symptoms of an underlying mental disorder. | There are 4 main categories of causes for adrenal fatigue: Neurological, Biochemical, Physical, and Mental/Emotional, each with their own types of chronic and acute stressors. Under Brain/Neurological, there is an overactive-right brain, meaning that the right brain has more connections to the stress response system (the flight-or-fight) system. | eng_Latn | 92 |
definition of parasympathetic nervous system | The parasympathetic nervous system (usually abbreviated PSNS, not PNS, to avoid confusion with the peripheral nervous system [PNS]) is one of the two divisions of the autonomic nervous system, the other being the sympathetic nervous system. | The parasympathetic nervous system is a division of the autonomic nervous system. It is involuntary, and acts with the sympathetic system to maintain body homeostasis.The actions of the parasympathetic nervous system are associated with the ârest and digestâ response.he parasympathetic nervous system is a division of the autonomic nervous system. It is involuntary, and acts with the sympathetic system to maintain body homeostasis. | eng_Latn | 93 |
when the parasympathetic nervous system is activated | The parasympathetic system is responsible for stimulation of rest-and-digest or feed and breed activities that occur when the body is at rest, especially after eating, including sexual arousal, salivation, lacrimation (tears), urination, digestion and defecation. | The parasympathetic nervous system (PNS) and sympathetic nervous system (SNS) work together to help you cope with and respond to daily life. For many people, daily life brings a myriad of stresses that activate the SNS. | eng_Latn | 94 |
what is hormone cortisol | Cortisol Hormone: The cortisol hormone is a key player in your bodyâs timeless fight or flight stress response and vital for supplying energy - fast! Cortisol stimulates the release of glucose, fats and amino acids into the bloodstream to meet those demands. But⦠too much of it for too long is a recipe for disaster! | Cortisol is a hormone in the adrenal cortex that surges in response to the release of ACTH, another hormone produced by the pituitary gland. Cortisol levels are a good indicator of adrenal and pituitary function. | eng_Latn | 95 |
does autonomic nervous system calm | 1 The peripheral nervous system is composed of the autonomic nervous system (ANS) and the peripheral nervous system (PNS). 2 The ANS is further divided into the sympathetic (activating) and parasympathetic (calming) nervous systems. 3 These divisions are activated by glands and organs in the endocrine system. | The autonomic nervous system (ANS) is a part of the central nervous system, which controls visceral functions of the human body, e.g. blood pressure, gut motility, emptying the urinary bladder, regulation of body temperature, etc. These regulations occur promptly. | eng_Latn | 96 |
what is prostaglandins definition | Prostaglandin: One of a number of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. | Prostaglandins function to activate an inflammatory response, which is the bodyâs way of neutralizing an infection caused by internal or external stimuli (burns, toxins, frostbite, radiation and splinters). Typical inflammatory responses include fever, the sensation of pain and swelling. | eng_Latn | 97 |
what proteins are directly affected by ADH | Vasopressin, also known as arginine vasopressin (AVP), antidiuretic hormone (ADH), or argipressin, is a neurohypophysial hormone found in most mammals.Its two primary functions are to retain water in the body and to constrict blood vessels.asopressin regulates the body's retention of water by acting to increase water reabsorption in the kidney's collecting ducts, the tubules which receive the very dilute urine produced by the functional unit of the kidney, the nephrons. | Function [edit]. The cell bodies produce the peptide hormone vasopressin, which is also known as anti-diuretic hormone (ADH). This chemical messenger travels via the bloodstream to its target cells in the papillary ducts in the kidneys, enhancing water reabsorption. In the cell bodies, the hormones are packaged in large, membrane-bound vesicles that are transported down the axons to the nerve endings. | eng_Latn | 98 |
what class of drug is dopamine | Trade names: Intropin®, Dopastat®, Revimine®. Mechanistic Class: sympathomimetic, dopaminergic and β 1 -adrenergic agonist. Therapeutic Class: vasopressor. Mechanism of action: Dopamine is a natural catecholamine neurotransmitter and is the biological precursor to norepinephrine.It increases heart rate, cardiac contractility and blood pressure by multiple mechanisms. Dopamine causes norepinephrine release from sympathetic nerve endings.echanism of action: Dopamine is a natural catecholamine neurotransmitter and is the biological precursor to norepinephrine. It increases heart rate, cardiac contractility and blood pressure by multiple mechanisms. | Dopamine is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the human brain and body, as well as elsewhere in biology. Its name derives from its chemical structure: it is an amine formed by removing a carboxyl group from a molecule of L-DOPA. | eng_Latn | 99 |
End of preview. Expand
in Dataset Viewer.
Dataset built from Nomic Contrastors for training embedding models. Some (query, pos) pairs are repeated. All (query, pos, neg) triplets are unique.
The query_lang attribute was calculated using fasttext language identification
- Downloads last month
- 12