Source: https://www.gwpharm.com/healthcare-professionals/research/scientific-publications
Timestamp: 2019-04-19 16:14:28+00:00

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Cannabidiol is approved in the U.S. and is an investigational product not approved for any indication outside the U.S. The publications provided on this website are for your information and interest only and comprise publications authored by or sponsored by GW Pharmaceuticals. This is not intended to be a comprehensive list, and they do not constitute and must not be relied on as medical or other professional advice. Each article cited is the property of its respective publisher. GW is not responsible for any technical or analytical inaccuracies in any publication not authored by GW, or the completeness of the selection of referenced publications. Links to sites outside of GW are provided as a resource to the viewer. GW accepts no responsibility for the content of linked sites.
DEVINSKY OPATEL AD, CROSS H, VILLANUEVA V, WIRRELL EC, PRIVITERA M, GREENWOOD SM, ROBERTS C, CHECKETTS D, VANLANDINGHAM KE, ZUBERI SM. N ENGL J MED. 2018 MAY 17;378:1888-97.
THIELE EA, MARSH ED, FRENCH JA, MAZURKIEWICZ-BELDZINSKA M, BENBADIS SR, JOSHI C, LYONS PD, TAYLOR A, ROBERTS C, SOMMERVILLE K. LANCET. 2018 JANUARY 24;391(10125):1085-96.
DEVINSKY O, CROSS H, LAUX L, MARSH E, MILLER I, NABBOUT R, SCHEFFER IE, THIELE EA, WRIGHT S. N ENGL J MED. 2017 MAY 25;376:2011-20.
Amada N, Yamasaki Y, Williams CM, Whalley BJ. PeerJ. 2013 Nov 21;1:e214.
Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models.
Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ. Br J Pharmacol. 2012 Dec;167(8):1629-42.
Hill AJ, Weston SE, Jones NA, Smith I, Bevan SA, Williamson EM, Stephens GJ, Williams CM, Whalley BJ. Epilepsia. 2010 Aug;51(8):1522-32.
Jones NA, Hill AJ, Smith I, Bevan SA, Williams CM, Whalley BJ, Stephens GJ. J Pharmacol Exp Ther. 2010 Feb;332(2):569-77.
Ma YL, Weston SE, Whalley BJ, Stephens GJ. Br J Pharmacol. 2008 May;154(1):204-15.
M.R. Pazos, V. Cinquina, A. Gómez , R. Layunta, M. Santos, J. Fernández-Ruiz, José Martínez-Orgado. Neuropharmacology, 2012. 63(5): p. 776-83.
Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5‑HT1A receptors.
Hind WH, England TE, O’Sullivan SE. Br J Pharmacol, 2016. 173(5): p. 815-25.
Hector Lafuente, M Ruth Pazos, Antonia Alvarez, Nagat Mohammed, Martín Santos, Maialen Arizti, Francisco J Alvarez and Jose Martinez-Orgado. Front Neurosci, 2016. 10: p. 323.
Neuroprotective effects of cannabidiol in hypoxic ischemic insult. The therapeutic window in newborn mice.
Mohammed N, Ceprián M, Jimenez L, Pazos MR, Saugstad OD, Martínez-Orgado J. CNS Neurol Disord Drug Targets, 2016 (Epub ahead of print).
Short-term effects of cannabidiol after severe global hypoxia-ischemia in newborn piglets.
Håvard T. Garberg, Marianne U. Huun, Javier Escobar, Jose Martinez-Orgado, Else-Marit Løberg, Rønnaug Solberg and Ola Didrik Saugstad. Pediatr Res, 2016 (Epub ahead of print).
Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: Role of 5HT1A and CB2 receptors.
Borrelli F, Fasolino I, Romano B, Capasso R, Maiello F, Coppola D, Orlando P, Battista G, Pagano E, Di Marzo V, Izzo AA. Biochem Pharmacol. 2013 May 1;85(9):1306-16.
De Petrocellis L, Orlando P, Moriello AS, Aviello G, Stott C, Izzo AA, Di Marzo V. Acta Physiol (Oxf). 2012 Feb;204(2):255-66.
Borrelli F, Aviello G, Romano B, Orlando P, Capasso R, Maiello F, Guadagno F, Petrosino S, Capasso F, Di Marzo V, Izzo AA. J Mol Med (Berl). 2009 Nov;87(11):1111-21.
Capasso R, Borrelli F, Aviello G, Romano B, Scalisi C, Capasso F, Izzo AA. Br J Pharmacol. 2008 Jul;154(5):1001-8.
Blake DR, Robson P, Ho M, et al. Rheumatology (Oxford). 2006;45(1):50-2.
Romano B, Pagano S, Orlando P, Capasso R, Cascio MG, Pertwee R, Marzo VD, Izzo AA, Borrelli F. Pharmacol Res, 2016. 113(Pt A): p. 199-208.
Pagano, E., V. Montanaro, A. Di Girolamo, A. Pistone, V. Altieri, J.K. Zjawiony, A.A. Izzo, and R. Capasso. Nat Prod Commun, 2015. 10(6): p. 1009-12.
Romano, B., F. Borrelli, I. Fasolino, R. Capasso, F. Piscitelli, M. Cascio, R. Pertwee, D. Coppola, L. Vassallo, P. Orlando, V. Di Marzo, and A. Izzo. Br J Pharmacol, 2013. 169(1): p. 213-29.
Izzo, A.A., R. Capasso, G. Aviello, F. Borrelli, B. Romano, F. Piscitelli, L. Gallo, F. Capasso, P. Orlando, and V. Di Marzo. Br J Pharmacol, 2012. 166(4): p. 1444-60.
Inhibitory effect of standardized cannabis sativa extract and its ingredient cannabidiol on rat and human bladder contractility.
Capasso, R., G. Aviello, F. Borrelli, B. Romano, M. Ferro, L. Castaldo, V. Montanaro, V. Altieri, and A.A. Izzo. Urology, 2011. 77(4): p. 1006 e91006 e15.
Inhibiting Heat Shock Proteins Can Potentiate the Cytotoxic Effect of Cannabidiol in Human Glioma Cells.
Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.
Nabissi M, Morelli MB, Offidani M, Amantini C, Gentili S, Soriani A, Cardinali C, Leoni P, Santoni G.
Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS. Philos Trans R Soc Lond B Biol Sci. 2012 Dec 5;367(1607):3364-78.
Neural mechanisms for the cannabinoid modulation of cognition and affect in man: a critical review of neuroimaging studies.
Bhattacharyya S, Atakan Z, Martin-Santos R, Crippa JA, McGuire PK. Curr Pharm Des. 2012;18(32):5045-54.
Deiana S, Watanabe A, Yamasaki Y, Amada N, Arthur M, Fleming S, Woodcock H, Dorward P, Pigliacampo B, Close S, Platt B, Riedel G. Psychopharmacology (Berl). 2012 Feb;219(3):859-73.
Gururajan A, Taylor DA, Malone DT. J Psychopharmacol. 2012 Oct;26(10):1317-32.
Bhattacharyya S, Morrison PD, Fusar-Poli P, Martin-Santos R, Borgwardt S, Winton-Brown T, Nosarti C, O' Carroll CM, Seal M, Allen P, Mehta MA, Stone JM, Tunstall N, Giampietro V, Kapur S, Murray RM, Zuardi AW, Crippa JA, Atakan Z, McGuire PK. Neuropsychopharmacology. 2010 Feb;35(3):764-74.
Zuardi AW, Crippa JA, Hallak JE, Moreira FA, Guimarães FS. Braz J Med Biol Res. 2006 Apr;39(4):421-9.
Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice.
Long LE, Malone DT, Taylor DA. Neuropsychopharmacology. 2006 Apr;31(4):795-803.

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