Source: https://ahduni.edu.in/dbls/people/faculty/sanjay-singh
Timestamp: 2019-04-25 21:43:51+00:00

Document:
Dr. Sanjay Singh is working as an Associate Professor at the Division of Biological & Life Sciences, School of Arts & Sciences, Ahmedabad University. He obtained his MS (Biochemistry) from University of Allahabad (2004), and Doctoral degree (Biotechnology) from CSIR-National Chemical Laboratory India (2008). He expanded his research interests during his stay as postdoctoral research fellow at University of Central Florida (Orlando, USA) and Pennsylvania State University (Hershey, USA).
Dr Singh's research group works on the synthesis of novel nanomaterials exhibiting biological enzyme-like properties, such as peroxidase, oxidase, catalase, and superoxide dismutase (SOD), which are exploited for the development of biosensors and detection of cells/tissues. His research group has found that nanozymatic activity of gold (Au) nanoparticles (NPs) could detect <100 cancer cells. Strategies are also being devised to enhance the nanozymatic activity of nanomaterials, which would enable easy detection of cancer cells with high specificity and sensitivity. Tuning the materials fundamental properties is another focus of his research group. These strategies are being used for designing of biosensing platform for the detection of biomolecules (such as glucose) from human blood serum in one step, which otherwise requires complicated two-step process at two different pH (4.0 and 7.4). His research is also focused on the synthesis and use of cerium oxide nanoparticles (CeNPs) exhibiting biological enzyme-like activities and currently, exploring the mechanism of free radical scavenging activity exhibited by CeNPs in several cell culture and animal models. Additionally, he also works on the encapsulation of multiple drugs and siRNAs (screened to exhibit synergy) in a single liposome platform for targeted killing of cancer cells, barring normal healthy human cells. Such nanoliposomes simultaneously deliver the anti-cancer agents to tumor cells, releasing them at the optimized synergizing ratio, leading to the reduced chances of development of resistance and metastasis. Such strategies are appraised by FDA because these NPs can deliver multiple agents as a single drug product than two separate ones, which could significantly reduce the cost and potentially be successful in the clinical trials.
Research Activity 1: Synthesis of multi target nanoconstruct for efficient delivery of therapeutic genes (plasmids and siRNA) for prostate cancer treatment.
Abstract: Prostate cancer is the second leading cause of cancer death in men and about one in nine will be diagnosed in his lifetime. Loss of PTEN has been considered as one of the major factors leading to the origin of prostate cancer through modulating PI3K/AKT signaling pathways. In this study, we have prepared a multifunctional antioxidant nanoliposome containing PTEN plasmid and cerium oxide nanoparticles (CeNPs). The efficient delivery of PTEN plasmid to human prostate cancer cells (PC-3) leads to restoration of the expression of lost PTEN protein in the cell cytoplasm. The delivered superoxide dismutase (SOD)-mimetic CeNPs were also found to decrease the cytoplasmic free radical levels in prostate cancer cells.
Research Activity 2: Development of redox-dependent catalase mimetic cerium oxide-based nanozyme for the protection of mammalian cells from reactive oxygen species.
Abstract: Recently, CeNPs have emerged as an effective therapeutic agent due to their redox-active nature encompassing the ability to switch between +4 or +3 oxidation states of surface “Ce” atoms. CeNPs with predominantly high Ce +4 oxidation state have been shown to exhibit biological catalase enzyme-like activity. Catalase enzyme is naturally present in mammalian cells and facilitates the protection from reactive oxygen species (ROS), generated due to decomposition of hydrogen peroxide (H2O2).
Research Activity 3: Development of novel nanomaterials-based nanozymes.
Abstract: Recently, there has been a lot of emphasis towards bimetallic materials- based artificial enzymes (Nanozymes) development due to the exhibition of superior biological enzyme-like activity. Such nanostructures offer easy tunability to the composition and therefore, facilitate the control over the enzyme-like activity. Owing to the disadvantages associated with natural biological enzymes, enormous interests has been devoted to developing novel artificial enzymes of next generation, which are resistant to those limitations and even outperform the natural enzymes. These nanozymes offer better sensitivity, specificity, operational stability, low cost of synthesis, purification, and storage. My research group is actively involved in the synthesis of novel nanomaterials-based nanozymes exhibiting the catalytic functions of important biological enzymes including superoxide dismutase, oxidase, peroxidase, and catalase. Some of these enzymes play essential roles in protection of mammalian cells from free radicals mediated oxidative insults (Antioxidant), whereas other enzymes produce free radicals by participating in other biochemical reactions (Pro-oxidant).
Figure: Inorganic nanoparticles as nanozymes.
N V S Vallabani, Sanjay Singh, A. Karakoti, Magnetic Nanoparticles: Current Trends and Future Aspects in Diagnostics and Nanomedicine, Current Drug Metabolism, 2019 (In Press).
Sanjay Singh, Nanomaterials exhibiting enzyme-like properties (Nanozymes): Current advances and future perspectives, Frontiers in Chemistry, 2019 (In press).
D. Jhala, H. Rather, D. Kedaria, J. Shah, Sanjay Singh, R. Vasita, Biomimetic PCL-Chitosan Nanofibrous substrate influenced cell cycle and ECM secretion affect cellular uptake of nanoclusters, Bioactive Materials, 2019, 4, 79 – 86.
NVS Vallabani, Sanjay Singh, Recent Advances and Future Prospects of Iron Oxide nanoparticles in Biomedicine and Diagnostics, 3Biotech, 2018, 8, 279.
Sanjay Singh , Raghu Asal, Stuti Bhagat, Multifunctional antioxidant nanoliposome-mediated delivery of PTEN plasmids restore the expression of tumor suppressor protein and induce apoptosis in prostate cancer cells, Journal of Biomedical Materials Research Part A, 2018, 106(12):3152-3164.
R. Singh, Sanjay Singh, Redox-dependent catalase mimetic cerium oxide-based nanozyme protect human hepatic cells from 3-AT induced acatalasemia, Colloids and Surfaces B: Biointerfaces, 2018, 175:625-635.
V. Patel, M. Singh, E.L.H. Mayes, A. Martinez, V. Shutthanandan, V. Bansal, Sanjay Singh, A.S. Karakoti, Ligand-mediated reversal of the oxidation state dependent ROS scavenging and enzyme mimicking activity of ceria nanoparticles, Chemical Communications, 2018, 54(99):13973-13976.
M N Karim, S R Anderson, Sanjay Singh, R Ramanathan, V Bansal, Nanostructured silver fabric as a free-standing NanoZyme for colorimetric detection of glucose in urine, Biosensors and Bioelectronics, 2018, 110, 8-15.
R. Singh, Sanjay Singh, Catalytically active cerium oxide nanoparticles protect mammalian cells from endogenous reactive oxygen species, Materials Today Proceedings, 2018 (In press).
R. Asal, S. Bhagat, Sanjay Singh, Development of liposome-based antioxidant nanoconstruct for efficient delivery of PTEN plasmid, Materials Today Proceedings, 2018 (In press).
M N Karim, M Singh, P Weerathunge, P Bian, R Zheng, C Dekiwadia, T Ahmed, S Walia, E D Gaspera, Sanjay Singh, R Ramanathan, V Bansal, Visible-Light-Triggered Reactive-Oxygen-Species-Mediated Antibacterial Activity of Peroxidase-Mimic CuO Nanorods. ACS Appl. Nano Mater, 2018, 1, 4, 1694 - 1704.
K. D. Shah, S. Bhagat, D. Varade, Sanjay Singh, Novel synthesis of polyoxyethylene cholesteryl ether coated Fe-Pt nanoalloys: A multifunctional and cytocompatible bimetallic alloy exhibiting intrinsic chemical catalysis and biological enzyme-like activities, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 553, 50–57.
M N Karim, S R Anderson, Sanjay Singh, R Ramanathan, V Bansal, Nanostructured silver fabric as a free-standing NanoZyme for colorimetric detection of glucose in urine. Biosensors and Bioelectronics, 2018, 110, 8-15.
R. Singh, Sanjay Singh, Uptake and Toxicity of different nanoparticles towards a tough bacterium: Deinococcus radiodurans, Advanced Materials Letters, 2018 (In press).
P Singh, Sanjay Singh, Gayatri S Pandi, Effective heart disease prediction system using data mining techniques, International Journal of Nanomedicine, 2018, 13, 121–124.
Sanjay Singh. Liposome encapsulation of doxorubicin and celecoxib in combination inhibits progression of human skin cancer cells, International Journal of Nanomedicine, 2018, 13, 11–13.
D Shah, R Savaliya, P Patel, K Kansara, A Pandya, A Dhawan, Sanjay Singh. Curcumin Ag nanoconjugates for improved therapeutic effects in cancer, International Journal of Nanomedicine, 2018, 13, 75–77.
P Patel, K Kansara, R Singh, R K Shukla, Sanjay Singh, A Dhawan, A Kumar, Cellular internalization and antioxidant activity of cerium oxide nanoparticles in human monocytic leukemia cells, International Journal of Nanomedicine, 2018, 13, 39–41.
R Purohit, Sanjay Singh, Fluorescent gold nanoclusters for efficient cancer cell targeting, International Journal of Nanomedicine, 2018, 13, 15–17.
J Sachaniya, R Savaliya, R Goyal, Sanjay Singh, Liposomal formulation of vitamin A for the potential treatment of osteoporosis, International Journal of Nanomedicine, 2018, 13, 51–53.
Juhi Shah, Sanjay Singh, Unveiling the Role of ATP in Amplification of Intrinsic Peroxidase-like Activity of Gold Nanoparticles, 3Biotech, 2018, 8 (1), 67.
Sanjay Singh. Catalytically Active Nanomaterials: Artificial Enzymes of Next Generation. Nanoscience & Technology: Open Access, 2018, 4(2), 1-6.
Stuti Bhagat, NV Srikanth Vallabani, Vaithiyalingam Shutthanandan, Mark Bowden, Ajay S Karakoti, Sanjay Singh, Gold core/ceria shell-based redox active nanozyme mimicking the biological multienzyme complex phenomenon, Journal of Colloid and Interface Science, 2017, 513:831-842.
H A Rather, R Singh, Sanjay Singh, R Thakore, D Jhala, R Vasita. Antioxidative study of Cerium Oxide nanoparticle functionalised PCL-Gelatin electrospun fibers for wound healing application, Bioactive Materials, 2018, 3(2), 201-211.
K D Shah, R Singh, Sanjay Singh. Cerium oxide based antioxidant nanozymes abrogate the organophosphate mediated oxidative stress in hepatocytes, Advanced Materials Letters, 2017 (Accepted).
NV Srikanth Vallabani, A S Karakoti, Sanjay Singh. ATP Catalyzed Peroxidase Mimetic Activity of Fe3O4 Nanoparticles at Physiological pH, Colloids and Surfaces B: Biointerfaces, 2017, 153, 52–60.
Sanjay Singh. Glucose decorated gold nanoclusters: A membrane potentialindependent fluorescence probe for rapid identification of cancer cellsexpressing Glut receptors, Colloids and Surfaces B: Biointerfaces, 2017, 155, 25–34.
B. Sargia, A. Karakoti, Sanjay Singh, Tailoring the antibacterial activity of redox active cerium oxide nanoparticles, Bulletin of Materials Science, 2017, 40, 6, 1231–1240.
R. Gowda, G. Kardos, A. Sharma, Sanjay Singh, G. P. Robertson, Nanoparticle-based Celecoxib and Plumbagin for the Synergistic Treatment of Melanoma, Molecular Cancer Therapeutics, 2017, 16(3), 440 - 452.
R.Singh, A. Karakoti, W. Self, S. Seal, Sanjay Singh. Redox-sensitive cerium oxide nanoparticles protect human keratinocytes from oxidative stress induced by glutathione depletion, Langmuir, 2016, 32 (46), 12202–12211.
Sanjay Singh. Cerium Oxide Based Nanozymes: Redox Phenomenon at Biointerfaces, Biointerphases, 2016, 11, 04B202.
Sanjay Singh, A. Kumar, Engineered Nanomaterials: Safety and Health Hazard, International Journal of Nanotechnology & Nanomedicine, 2016, 1, 1-23.
R Purohit, S Vallabani, RK Shukla, A Kumar, S Singh, Effect of Gold Nanoparticle Size and Surface Coating on Human Red Blood Cells, Bioinspired, Biomimetic and Nanobiomaterials, 2016, 5 (3), 121-131.
R Savaliya, P Singh, Sanjay Singh, “Pharmacological drug delivery strategies for improved therapeutic effects: Recent advances”, Current Pharmaceutical Design, 2016, 22(11), 1506-20. (Highlighted by World Biomedical Frontiers, http://biomedfrontiers.org/newtech-2016-7/) .
A Pandya, A Tripathi, R Purohit, Sanjay Singh, M I. Nandasirid, A Karakoti , S P. Singh, R Shanker, “Fluorescent Magnesium Nanocomplex in Protein Scaffold for Cell Nuclei Imaging Application”, RSC Advances, 2015, 5, 94236-94240.
R. Savaliya, D.Shah, R. Singh, A. Kumar, R. Shanker, A. Dhawan, Sanjay Singh, Nanotechnology in Disease Diagnostic Techniques, Current Drug Metabolism, 2015, 16(8), 645-661.
J. Shah, R. Purohit, R. Singh, A. S. Karakoti, Sanjay Singh, ATP-enhanced peroxidase-like activity of gold nanoparticles, Journal of Colloid and Interface Science, 2015, 415, 100-107.
A. S. Karakoti, R. K. Shukla, R. Shanker, Sanjay Singh, Surface Functionalization of Quantum Dots for Biological Applications, Advances in Colloid and Interface Science, 2015, 215, 28-45.
K. Kansara, P. Patel, D. Shah, R. K. Shukla, Sanjay Singh, A. Kumar, A. Dhawan, TiO2 Nanoparticle induce DNA double strand breaks and cell cycle arrest in human alveolar cells, Environment and Molecular Mutagenesis, 2015, 56, 204–217.
R. Singh, Sanjay Singh, Role of Phosphate on Stability and Catalase Mimetic Activity of Cerium Oxide Nanoparticles, Colloids and Surfaces B: Biointerfaces, 2015, 132, 78-84.
Sanjay Singh, “Nanomaterials as Non-viral siRNA Delivery Agents for Cancer Therapy”, BioImpacts, 2013, 3(2), 53-65.
S. Das, Sanjay Singh, D. Joung, J. Dowding, D. Reid, L. Zhai, S. Khondaker, WT. Self, S. Seal, “Oxygenated Functional Group Density on Graphene Oxide: Its Effect on Cell Toxicity”, Particle & Particle Systems Characterization, 2013, 30 (2), 148-157.
S. M. Hirst, A. Karakoti, Sanjay Singh, W. T. Self, S. Seal, C. M. Reilly, “Bio-distribution and In vivo Antioxidant Properties of Cerium Oxide Nanoparticles” Environmental Toxicology, 2013, 28(2), 107-118.
Sanjay Singh, A. Sharma, G. Robertson, “Realizing the Clinical Potential of Cancer Nanotechnology by Minimizing Toxicological and Targeted Delivery Concerns” Cancer Research, 2012, 72 (22), 5663-8.
S. Das*, Sanjay Singh*, J. Dowding, S. Oommen, A. Kumar, CR. Patra, NE. Vlahakis, D. Mukhopadhyay, WT. Self, S. Seal, “The induction of angiogenesis by cerium oxide nanoparticles through the modulation of oxygen in intracellular environments”, Biomaterials 2012, 33 (31), 7746-55. *Equal contribution.
M. Srivastava, Sanjay Singh, WT. Self, “Exposure to Silver Nanoparticles Inhibits Selenoprotein Synthesis and the Activity of Thioredoxin Reductase through Release of Silver Ions” Environmental Health Perspective, 2012, 120, 56-61.
V. Singh, Sanjay Singh, S. Das, A. Kumar, W.T. Self, S. Seal, “A facile synthesis of PLGA encapsulated cerium oxide nano particles: Release kinetics and biological activity” Nanoscale 2012, 4, 2597-2605.
Sanjay Singh, T. Pirmohamed, A. S. Karakoti, A. Kumar, S. Seal, WT. Self, “A phosphate-dependent shift in redox state of cerium oxide nanoparticles leads to altered catalytic properties” Biomaterials, 2011, 32, 6745-6753.
T. Pirmohamed, J. M. Dowding, Sanjay Singh, B. Wasserman, E. Heckert, A. Karakoti, J. E. S. King, S. Seal, WT. Self, “Nanoceria exhibit redox state-dependent catalase mimetic activity” Chem. Commun., 2010, 46, 2736-2738.
Sanjay Singh, V. D’ Britto, A. Dhawan, M. Sastry, B. L. V. Prasad, “Bacterial Synthesis of Photo catalytically Active and Biocompatible TiO2 and ZnO Nanoparticles” International Journal of Green Nanotechnology 2010, 2, 80-99.
Sanjay Singh, A. Kumar, A. Karakoti, S. Seal, WT. Self, “Unveiling the mechanism of uptake and sub-cellular distribution of cerium oxide nanoparticles” Mol. BioSyst., 2010, 6, 1813-1820.
A. Karakoti, Sanjay Singh, J. M. Dowding, S. Seal, WT. Self, “Redox-active Radical Scavenging Nanomaterials” Chem. Soc. Rev., 2010, 39, 4422-4432.
Sanjay Singh, V. D’ Britto, A. Prabhune, A. Dhawan, C. V. Ramanna, B. L. V. Prasad, “Cytotoxic and Genotoxic Assessment of Glycolipid Reduced/Capped Gold and Silver Nanoparticles” New J. Chem., 2010, 34, 294-301.
Sanjay Singh, S. Jaiswal, P. Patel, A. A. Prabhune, C. V. Ramana, B. L. V. Prasad, “A direct method for the preparation of glycolipid-metal nanoparticle conjugates: sophorolipids as reducing and capping agents for the synthesis of water re-dispersible silver nanoparticles and their antibacterial activity” New J. Chem., 2009, 33, 646-652.
A. Kumar, Sanjay Singh, A. Prabhune, P. Poddar, A. Pundle, “Effect of Cultural Conditions and Media Constituents on Production of Penicillin V Acylase and CTAB Treatment to Enhance Whole-Cell Enzyme Activity of Rhodotorula aurantiaca (NCIM 3425)” Appl. Biochem. Biotechnol., 2009, 157, 463-472.
A. Karakoti, Sanjay Singh, A. Kumar, M. Malinska, SVNT. Kuchibhatla, K. Wozniak, WT. Self, and S. Seal, “PEGylated Nanoceria as Radical Scavenger with Tunable Redox Chemistry” J. Am. Chem. Soc., 2009, 131, 14144-14145.
S. S. Hasan, Sanjay Singh, R. Y. Parikh, M. S. Dharne, M. S. Patole, B. L. V. Prasad, Y. S. Shouche, “Bacterial synthesis of Copper/Copper Oxide Nanoparticles” J. Nanosc. Nanotech., 2008, 8, 3191-3196.
S. Kulkarni, A. Sayed, Sanjay Singh, A. Gaikwad, K. Vijayamohanan, A. Ahmed, S. Ogale, “Silicate nanoparticles by bioleaching of glass and modification of the glass surface” J. Non Crystalline Solids, 2008, 354, 3433.
R. Parikh, Sanjay Singh, B. L. V. Prasad, M. S. Patole, M. Sastry, Y. S. Souche, “Extracellular synthesis of crystalline silver nanoparticles and molecular evidence of silver resistance from Morganella sp.: Towards understanding biochemical synthesis mechanism” ChemBioChem., 2008, 9, 1415-1422.
Sanjay Singh, U. M. Bhatta, P. V. Satyam, Alok Dhawan, Murali Sastry, B. L. V. Prasad, “Bacterial Synthesis of Silicon/Silica nanocomposites” J. Mater. Chem., 2008, 18, 2601-2606.
Sanjay Singh, B. L. V. Prasad, “Nearly Complete Oxidation of Au0 in Hydrophobized Nanoparticles to Au3+ ions by N-Bromosuccinimide” J. Phys. Chem. C, 2007, 111, 14348-14352.
M. Kasture, Sanjay Singh, P. Patel, P. A. Joy, A. A. Prabhune, C. V. Ramana, B. L. V. Prasad, Multiutility sophorolipids as nanoparticle capping agents: Synthesis of stable and water dispersible Co nanoparticles” Langmuir, 2007, 23, 11409-11412.
Sanjay Singh, R. Pasricha, U. M. Bhatta, P. V. Satyam, M. Sastry, B. L. V. Prasad, “Effect of halogen addition to monolayer protected gold nanoparticles” J. Mater. Chem., 2007, 16, 1614-1619.
G P. Robertson, C D. Raghavendra gowda, A K. Sharma, Sanjay Singh. Compositions and methods including celecoxib and plumbagin relating to treatment of cancer, US Patent 2014 (Applied).
Pal Patel, Krupa Kansara, Darshini Shah, NV Srikanth Vallabani, Ritesh K Shukla, Sanjay Singh, Alok Dhawan, Ashutosh Kumar, “Cytotoxicity assessment of ZnO nanoparticles on human epidermal cells” Molecular Cytogenetics, 2014, 7(Suppl 1), P81.
Krupa Kansara, Pal Patel, Darshini Shah, NV Srikanth Vallabani, Ritesh K Shukla, Sanjay Singh, Ashutosh Kumar, Alok Dhawan, “TiO2 nanoparticles induce cytotoxicity and genotoxicity in human alveolar cells” Molecular Cytogenetics, 2014, 7(Suppl 1), P77.
Rahul Purohit, NV Srikanth Vallabani, Ritesh K Shukla, Ashutosh Kumar, Alok Dhawan, Sanjay Singh, “BSA coated gold nanoparticles exhibit size dependent interaction with lung cancer (A549) cells” Molecular Cytogenetics, 2014, 7(Suppl 1), P83.
Ritesh K Shukla, Ashutosh Kumar, NV Srikanth Vallabani, Sanjay Singh, Alok Dhawan, “TiO2 NPs induced hepatic injury in mammals: a mechanistic approach” Molecular Cytogenetics, 2014, 7(Suppl 1), P82.
Ragini Singh, Ritesh K. Shukla, Ashutosh Kumar, Alok Dhawan, Sanjay Singh, “PEGylated nanoceria protect human epidermal cells from reactive oxygen species” Molecular Cytogenetics, 2014 7(Suppl 1), P78.
NV Srikanth Vallabani, Ritesh K Shukla, Dinesh Konka, Ashutosh Kumar, Sanjay Singh, Alok Dhawan, “TiO2 nanoparticles induced micronucleus formation in human liver (HepG2) cells: comparison of conventional and flow cytometry based methods” Molecular Cytogenetics, 2014 7(Suppl 1), P79.
“International Nanobioscience Conference” (INBC-2006), Pune, India, August 06-08, 2006, Organized by Agharkar Research Institute, Pune, India.
Understanding the Molecular Mechanism of Extracellular Synthesis of Crystalline Silver Nanoparticles from the bacterium S-V42. RY Parikh, Sanjay Singh, BLV Prasad, M. Sastry, Y. Shouche. “NSTI Nanotechnology conference and Expo.” From May 20-24, 2007 organized at Santa Clara Convention Center, Santa Clara, USA.
Synthesis of Silver Nanoparticles using Sophorolipids as Capping and Reducing agents and Their Antimicrobial Activity. Sanjay Singh, A. Prabhune, BLV Prasad, First winter school on “Nanotechnology in Advanced Drug Delivery”, December 2-6, 2007, Organized at National Institute of Pharmaceutical Education and Research (NIPER), Mohali, Chandigrah, INDIA.
Bacterial Synthesis of Silicon/Silica nanocomposites. Sanjay Singh, U. M. Bhatta, P. V. Satyam, A. Dhawan, M. Sastry, B. L. V. Prasad, “International Conference on Nanomaterial Toxicology” (ICONTOX) being organized at Lucknow by Industrial Toxicology Research Centre and Indian Nanoscience Society during February 5-7, 2008.
Biosynthesis of Gold and Silver nanoparticles and their toxicity studies on mammalian cells thereof. Virginia D’Britto, Sanjay Singh, A. Dhawan, B.L.V. Prasad, “International Conference on Nanomaterial Toxicology” (ICONTOX) being organized at Lucknow by Industrial Toxicology Research Centre and Indian Nanoscience Society during February 5-7, 2008. (Best Poster Award).
Bacterial Synthesis of Titania Nanoparticles and its Photocatalytic Applications. Sanjay Singh, M. Sastry, BLV Prasad. “The International Conference on Nanoscience and Technology” (ICONSAT) organized at Chennai, Tamil Nadu during February 27-29, 2008.
Cellular Uptake Mechanism of Carboxyfluorescein Modified Ceria Nanoparticles in Human Keratinocyte cells. Sanjay Singh, A. Kumar, A. Karakoti, S. Seal, W. Self, “NSTI Nanotechnology conference and Expo.” From May 3-7, 2009 at the George R. Brown Convention Center in Houston, Texas, USA.
Cellular uptake mechanism of Nanoceria in Human Keratinocytes. Sanjay Singh, A. Kumar, A. Karakoti, S. Seal, W. Self, “NANOFLORIDA-2009” organized by University of Central Florida, Florida from September 25-26, 2009.
Antibiofilm activity of Hydrophobic Silver Nanoparticle films against Vancomycin resistant bacterial species, E. faecalis. Sanjay Singh, M. Srivastava, A. Kumar, A. Karakoti, S. Seal, W. Self, “American Society for Microbiology” (ASM) organized at Islamorada, Florida (Florida Keys) from October 10-11, 2009.
Redox activity of cerium oxide nanoparticles for scavenging radicals – Activity and regeneration. A. Karakoti, JES King, Sanjay Singh, T. Inerbaev, A. Masunov, W. Self, S. Seal, “MRS” (Materials Research Society), November 2009, Boston, USA.
Nanocerium oxide as Antioxidant –Role of Environment and Surface Coating on the Interaction with Reactive Oxygen Species. A. Karakoti, Sanjay Singh, A. Kumar, SNVT Kuchibhatla, W. Self, S. Seal, November 2009, “AVS”, San Jose, USA.
PEGylated Nanoceria: An Efficient Antioxidant in Glutathione depleted Mammalian cells. Sanjay Singh, J. Dowding, A. Karakoti, S. Seal, W. Self, “NSTI Nanotechnology conference and Expo.” From June 21-25, 2010 at the Anaheim Convention Center, Anaheim, California USA.
Cerium oxide nanoparticles protect cells against oxidative stress induced by glutathione depletion. Sanjay Singh, J. Dowding, A. Karakoti, S. Seal, W. Self, “Society for Free Radical Biology and Medicine” (SFRBM) from November 17-21, 2010, organized at Caribe Royale Hotel & Convention center, Orlando, Florida, USA.
Pro-angiogenic properties of cerium oxide nanoparticles: Role of surface Ce3+/Ce4+ ratio on induction of tube formation. S. Das, Sanjay Singh, JM Dowding, S. Oommen, A. Kumar, CR Patra, NE Vlahakis, D Mukhopadhyay, WT Self, S Seal, International conference “NanoTech 2011”, Boston, MA, USA, June 13-16, 2011.
Cell toxicity of GO/RGO: function of size and oxygenated functional group density. S. Das, Sanjay Singh, V. Singh, D. Joung, J. Dowding, R. McCormack, L. Zhai, S. I. Khondaker, W. T. Self, S. Seal. Presented in “2012 annual meeting and exhibition of The Minerals, Metals & Materials Society” Orlando, FL, USA, March 11-15, 2012.
Cerium oxide nanoparticles can induce pro-angiogenesis and facilitate wound healing. S. Das, S. Chigurupati, Sanjay Singh, M. R. Mughal, A. Kumar, C.R. Patra, S. Oommen, N. E. Vlahakis, D. Mukhopadhyay, W. T Self, M. P. Mattson, S. Seal. Presented in “22nd Wound Healing Society Annual Meeting” Georgia World Congress Center, Atlanta, Georgia, USA, April 19-22, 2012.
Cytotoxicity assessment of ZnO nanoparticles on human epidermal cells. Pal Patel, Krupa Kansara, Darshini Shah, NV Srikanth Vallabani, Ritesh K Shukla, Sanjay Singh, Alok Dhawan, Ashutosh Kumar, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
TiO2 nanoparticles induce cytotoxicity and genotoxicity in human alveolar cells. Krupa Kansara, Pal Patel, Darshini Shah, NV Srikanth Vallabani, Ritesh K Shukla, Sanjay Singh, Ashutosh Kumar, Alok Dhawan, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
BSA coated gold nanoparticles exhibit size dependent interaction with lung cancer (A549) cells. Rahul Purohit, NV Srikanth Vallabani, Ritesh K Shukla, Ashutosh Kumar, Alok Dhawan, Sanjay Singh, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
TiO2 NPs induced hepatic injury in mammals: a mechanistic approach. Ritesh K Shukla, Ashutosh Kumar, NV Srikanth Vallabani, Sanjay Singh, Alok Dhawan, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
PEGylated nanoceria protect human epidermal cells from reactive oxygen species. Ragini Singh, Ritesh K. Shukla, Ashutosh Kumar, Alok Dhawan, Sanjay Singh, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
TiO2 nanoparticles induced micronucleus formation in human liver (HepG2) cells: comparison of conventional and flow cytometry based methods NV Srikanth Vallabani, Ritesh K Shukla, Dinesh Konka, Ashutosh Kumar, Sanjay Singh, Alok Dhawan, presented in “International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics” at the Ahmedabad Management Association, Ahmedabad, India, from 22nd – 25th January, 2014.
The size effect of Bovine Serum Albumin Coated Gold Nanoparticles on Cellular Internalization. Sanjay Singh, Rahul Purohit, NV Srikanth Vallabani, Ritesh K Shukla, Ashutosh Kumar, Alok Dhawan, presented in NANOTOX 2014, 7th International Nanotoxicology Congress, held from 23-26 April 2014 in Antalya, Turkey, 2014, P387.
Liposomes carrying doxorubicin and celecoxib in one platform inhibit progression of skin carcinoma cells. Sanjay Singh, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Curcumin silver nanoconjugates for improved therapeutic effects in cancerous cells. Darshini Shah, Reema Savaliya, Pal Patel, Krupa Kansara, Monika Patel, Alok Pandya, Alok Dhawan, Sanjay Singh, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Effective heart disease prediction system using data mining techniques. Poornima Singh, Sanjay Singh, Gayatri S Pandi, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Cancer cell imaging and cytotoxicity of novel synthesized bioconjugated luminescent magnesium nanoparticles. Alok Pandya, Apritam Tripathi, Surinder Singh, Sanjay Singh, Rishi Shanker, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Liposomal formulation of vitamin A for the potential treatment of osteoporosis. Jainy Sachaniya, Reema Savalia, Ramesh Goyal, Sanjay Singh, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Size dependent peroxidase like activity of citrate capped gold nanoparticles. Juhi Shah, Rahul Purohit, Ragini Singh, Alok Dhawan, Sanjay Singh, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Cellular internalization and antioxidant activity of cerium oxide nanoparticles in human monocytic leukemia cells. Pal Patel, Krupa Kansara, Ragini Singh, Ritesh K Shukla, Sanjay Singh, Alok Dhawan, Ashutosh Kumar, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Role of phosphate in stability and catalytic activity of cerium oxide nanoparticles. Ragini Singh, Sanjay Singh, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Synthesis and detection of peroxidase like activity of citrate coated iron oxide nanoparticles. NV Srikanth Vallabani, Konka Dinesh, Rahul Purohit, Sanjay Singh, Alok Dhawan, presented in “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014. (Best Poster Award).
Multi target antioxidant nanoconstruct for prostate cancer treatment, Sanjay Singh, “SERB – Young Scientists Meeting”, organised at Manipal University, Mangalore, India from 11th – 12th August 2016.
8th International Symposium on Current Trends in Healthcare “Advances in New Drug Discovery & Development”. Organizing By Ramanbhai Foundation, Zyduscadila, at Ahmedabad, India from 2nd – 4th February 2017.
Sanjay Singh, Gold-core/Cerium-oxide shell nanostructure: A redox active nanozyme mimicking triple enzyme activities, International conference on BioMaterials, BioEngineering, and BioTheranostics (BIOMET 2018), VIT Vellore, 2018.
Sanjay Singh, Investigating the role of catalase mimetic cerium oxide-based nanozyme to impart protection to hepatic cells from acatalasia, 25th Annual Conference of the Society for Redox Biology & Medicine, Chicago, Illinois, USA, 2018.
Sanjay Singh, Nanozymes for Sensing and Therapeutic Applications, National Conference on Advances in Spectroscopy: Molecules to Materials NCASMM 2018, IITRAM Ahmedabad, India, 2018.
Stuti Bhagat and Sanjay Singh, Multifunctional antioxidant nanoliposome-mediated delivery of PTEN plasmids restore the expression of tumor suppressor protein and induce apoptosis in prostate cancer cells, National Conference on Advances in Spectroscopy: Molecules to Materials, IITRAM Ahmedabad, India, 2018.
Vidhi Jain, Stuti Bhagat, Sanjay Singh, Replacement of Cetyltrimethylammonium Bromide by 11- Mercaptoundecanoic acid from the surface of Au/CeO2 core-shell nanoparticles that retain their nanozymatic properties, National Conference on Advances in Spectroscopy: Molecules to Materials, IITRAM Ahmedabad, India, 2018.
Juhi Shah, Alok Pandya, Sanjay Singh, Catalase Mimetic Activity of BSA Conjugated Magnesium Based Nanozymes And its Protection in Human Hepatocytes Cells From Oxidative Stress, National Conference on Advances in Spectroscopy: Molecules to Materials, IITRAM Ahmedabad, India, 2018.
Sanjay Singh. “Synthesis, characterizations and toxicity of Nanomaterials”, October 04, 2008 at University of Central Florida, Orlando, USA.
Cellular uptake mechanism of Nanoceria in Human Keratinocytes. Sanjay Singh, A. Kumar, A. Karakoti, S. Seal, W. Self, “NANOFLORIDA-2009” organized by University of Central Florida, Orlando, USA.
Sanjay Singh. “Activity of Nanoparticles in Biologically Relevant Media and Mechanism of Cellular Uptake” January 03, 2011 at Pacific Northwest National Laboratory, Washington, USA.
Sanjay Singh. “Synthesis and biomedical applications of nanoparticles”, March 07, 2012 at The Sheikh Zayed Institute of Pediatric Surgical Innovation Children’s National Medical Center, Washington DC, USA.
Sanjay Singh. “Introduction to Nanobiotechnology” NASI supported one day workshop on Nanotechnology at Government Science College, Ahmedabad, Gujarat, India on October 10, 2013.
Sanjay Singh. INDO-UK SEMINAR on “Environmental Impact and Hazard Identification of Engineered Nanomaterials” February 24-26, 2014, held at Institute of Life Sciences, Ahmedabad University, Gujarat, India.
Sanjay Singh. “Liposomes carrying doxorubicin and celecoxib in one platform inhibit progression of skin carcinoma cells” at “International Conference on Translational Nanomedicine (T-NANO)-2014”, at the Ahmedabad Management Association, Ahmedabad, India, from 15th – 17th December 2014.
Sanjay Singh, Multi target antioxidant nanoconstruct for prostate cancer treatment, “SERB – Young Scientists Meeting”, organised at Manipal University, Mangalore, India from 11th – 12th August 2016.
Sanjay Singh, Redox state dependent scavenging of phosphate by cerium oxide nanoparticles as an antibacterial strategy, International Conference on Nanomaterials and Nanotechnology (ICNANO-2017), organized by Vinoba Bhave Research Institute (VBRI), Allahabad from March 01 – 03, 2017.
Ad-hoc reviewer for several International Peer-reviewed Journals (Nanomedicine: Nanotechnology-Biology and Medicine, Nanoscale, Natural Product Communications, Biomacromolecules, RSC Advances, Electrochemistry Communications, Mutagenesis, Journal of Translational Toxicology, Science of Advanced Materials, Cancer Management and Research, International Journal of Nanomedicine and PLoS One) etc.
Editorial Board Member “American Journal of Nanoscience and Nanotechnology”, since 2013.
Member AVS (American Vacuum Society) – 2016-17.
Member “International Association of Advanced Materials” (IAAM) – 2017–22.
Consulting editor for a Dove Press journal “Research and Reports in Transdermal Drug Delivery”, since 2015.
Editorial Board member for International Journal of Medical Sciences (IJME), since 2015.
Guest editor for 23rd Annual Meeting of the Society for Redox Biology and Medicine (SfRBM), to be held November 16-19, 2016 in San Francisco, California USA.
2018: Best Professor in Nanoscience and Nanobiotechnology in the Gujarat region by "Dewang Mehta National Education Awards"

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