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A range of viruses and bacteria (as well as parasites) can infect the human alimentary canal. Mixed infections of viruses and bacteria are not uncommon, and quite complex physiological changes can result from such infections. This chapter documents the main viruses and bacteria involved in mixed gastroenteritis infections, and then surveys the frequency and nature of mixed viral-bacterial infections in humans. The literature on the possible mechanisms of such mixed infections is then examined under four headings: (i) the occurrence of asymptomatic infections by viral and bacterial enteropathogens; (ii) the clinical features of natural mixed infections in humans; (iii) the nature of mixed infections in animal models; (iv) relevant in vitro studies of viral-bacterial interaction.
1. Albert, M. J.,, A. S. G. Faruque,, S. M. Faruque,, R. B. Sack,, and D. Mahalanabis. 1999. Case-control study of enteropathogens associated with childhood diarrhea in Dhaka, Bangladesh. J. Clin. Microbiol. 37: 3458– 3464.
2. Barnes, G. L.,, E. Uren,, K. B. Stevens,, and R. F. Bishop. 1998. Etiology of acute gastroenteritis in hospitalized children in Melbourne, Australia, from April 1980 to March 1993. J. Clin. Microbiol. 36: 133– 138.
3. Barton, M. D.,, V. Kolega,, and S. G. Fenwick,. 1997. Yersinia enterocolitica, p. 493– 519. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
4. Bates, J. R., 1997. Clostridium perfringens, p. 407– 427. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
5. Benfield, D. A.,, D. H. Francis,, J. P. McAdaragh,, D. D. Johnson,, M. E. Bergeland,, K. Rossow,, and R. Moore. 1988. Combined rotavirus and K99 Escherichia coli infection in gnotobiotic pigs. Am. J. Vet. Res. 49: 330– 337.
6. Benko, M.,, B. Harrach,, and W. C. Russell,. 2000. Family Adenoviridae, p. 227– 238. In M. H. V. van Regenmortel,, C. M. Fauquet,, D. H. L. Bishop,, E. B. Carstens,, M. K. Estes,, S. M. Lemon,, J. Maniloff,, M. A. Mayo,, D. J. McGeoch,, C. R. Pringle,, and R. B. Wickner (ed.), Virus Taxonomy. Academic Press, San Diego, Calif.
7. Bettelheim, K. A.,, V. Bennett-Wood,, D. Lightfoot,, P. J. Wright,, and J. A. Marshall. 2001. Simultaneous isolation of verotoxin-producing strains of Escherichia coli O128: H2 and viruses in gastroenteritis outbreaks. Comp. Immunol. Microbiol. Infect. Dis. 24: 135– 142.
8. Bettelheim, K. A.,, D. S. Bowden,, J. C. Doultree,, M. G. Catton,, D. Chibo,, N. J. P. Ryan,, P. J. Wright,, I. C. Gunesekere,, J. M. Griffith,, D. Lightfoot,, G. G. Hogg,, V. Bennett- Wood,, and J. A. Marshall. 1999. Combined infection of Norwalk-like virus and verotoxin- producing bacteria associated with a gastroenteritis outbreak. J. Diarrhoeal Dis. Res. 17: 34– 36.
9. Bishop, R. F., 1994. Natural history of human rotavirus infections, p. 131– 167. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract. 2nd ed. Marcel Dekker Inc., New York, N.Y.
10. Bon, F.,, P. Fascia,, M. Dauvergne,, D. Tenenbaum,, H. Planson,, A. M. Petion,, P. Pothier,, and E. Kohli. 1999. Prevalence of group A rotavirus, human calicivirus, astrovirus and adenovirus type 40 and 41 infections among children with acute gastroenteritis in Dijon, France. J. Clin. Microbiol. 37: 3055– 3058.
11. Bukholm, G. 1988. Human rotavirus infection enhances invasiveness of enterobacteria in MA- 104 cells. APMIS 96: 1118– 1124.
12. Bukholm, G.,, K. Bjornland,, H. Ellekjaer,, B. P. Berdal,, and M. Degre. 1988. Vesicular stomatitis virus infection enhances invasiveness of Salmonella typhimurium. APMIS 96: 400– 406.
13. Bukholm, G.,, and M. Degre. 1984. Invasiveness of Salmonella typhimurium in HEp-2 cell cultures preinfected with coxsackie B 1 virus. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 92: 45– 51.
14. Bukholm, G.,, M. Holberg-Petersen,, and M. Degre. 1985. Invasiveness of Salmonella typhimurium in HEp-2 cell cultures pretreated with UV-inactivated coxsackie virus. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 93: 61– 65.
15. Bukholm, G.,, K. Modalsli,, and M. Degre. 1986. Effect of measles-virus infection and interferon treatment on invasiveness of Shigella flexneri in HEp2-cell cultures. J. Med. Microbiol. 22: 335– 341.
16. Cauchi, M. R.,, J. C. Doultree,, J. A. Marshall,, and P. J. Wright. 1996. Molecular characterization of Camberwell virus and sequence variation in ORF3 of small round-structured (Norwalk-like) viruses. J. Med. Virol. 49: 70– 76.
17. Caul, E. O., 1994. Human coronaviruses, p. 603– 625. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
18. Caul, E. O. 1996. Viral gastroenteritis: small round structured viruses, caliciviruses and astroviruses. Part I. The clinical and diagnostic perspective. J. Clin. Pathol. (London) 49: 874– 880.
19. Cox, E.,, V. Cools,, H. Thoonen,, J. Hoorens,, and A. Houvenaghel. 1988. Effect of experimentally- induced villus atrophy on adhesion of K88ac-positive Escherichia coli in just-weaned piglets. Vet. Microbiol. 17: 159– 169.
20. Cox, G. J.,, S. M. Matsui,, R. S. Lo,, M. Hinds,, R. A. Bowden,, R. C. Hackman,, W. G. Meyer,, M. Mori,, P. I. Tarr,, L. S. Oshiro,, J. E. Ludert,, J. D. Meyers,, and G. B. Mc- Donald. 1994. Etiology and outcome of diarrhea after marrow transplantation: a prospective study. Gastroenterology 107: 1398– 1407.
21. Cravioto, A.,, A. Tello,, A. Navarro,, J. Ruiz,, H. Villafan,, F. Uribe,, and C. Eslava. 1991. Association of Escherichia coli HEp-2 adherence patterns with type and duration of diarrhoea. Lancet 337: 262– 264.
22. Cruz, J. R.,, A. V. Bartlett,, J. E. Herrmann,, P. Caceres,, N. R. Blacklow,, and F. Cano. 1992. Astrovirus-associated diarrhea among Guatemalan ambulatory rural children. J. Clin. Microbiol. 30: 1140– 1144.
23. Cubitt, W. D., 1994. Caliciviruses, p. 549– 568. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
24. Desmarchelier, P. M., 1997. Pathogenic vibrios, p. 285– 312. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
25. Desmarchelier, P. M.,, and F. H. Grau,. 1997. Escherichia coli, p. 231– 264. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
26. Di Biase, A. M.,, G. Petrone,, M. P. Conte,, L. Seganti,, M. G. Ammendolia,, A. Tinari,, F. Iosi,, M. Marchetti,, and F. Superti. 2000. Infection of human enterocyte-like cells with rotavirus enhances invasiveness of Yersinia enterocolitica and Y. pseudotuberculosis. J. Med. Microbiol. 49: 897– 904.
27. Donta, S. T.,, R. B. Wallace,, S. C. Whipp,, and J. Olarte. 1977. Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J. Infect. Dis. 135: 482– 485.
28. Echeverria, P.,, N. R. Blacklow,, J. L. Vollet III,, C. V. Ulyangco,, G. Cukor,, V. B. Soriano,, H. L. Du Pont,, J. H. Cross,, F. Orskov,, and I. Orskov. 1978. Reovirus-like agent and enterotoxigenic Escherichia coli infections in pediatric diarrhea in the Philippines. J. Infect. Dis. 138: 326– 332.
29. Enjuanes, L.,, D. Brian,, D. Cavanagh,, K. Holmes,, M. M. C. Lai,, H. Laude,, P. Masters,, P. J. M. Rottier,, S. G. Siddell,, W. J. M. Spaan,, F. Taguchi,, and P. Talbot,. 2000. Family Coronaviridae, p. 835– 849. In M. H. V. van Regenmortel,, C. M. Fauquet,, D. H. L. Bishop,, E. B. Carstens,, M. K. Estes,, S. M. Lemon,, J. Maniloff,, M. A. Mayo,, D. J. McGeoch,, C. R. Pringle,, and R. B. Wickner (ed.), Virus Taxonomy. Academic Press, San Diego, Calif.
30. Estes, M. K.,, G. Kang,, C. Q.-Y. Zeng,, S. E. Crawford,, and M. Ciarlet,. 2001. Pathogenesis of rotavirus gastroenteritis, p. 82– 100. In D. Chadwick,, and J. A. Goode (ed.), Gastroenteritis Viruses. John Wiley and Sons, Ltd., Chichester, United Kingdom.
31. Evans, D. G.,, J. Olarte,, H. L. Du Pont,, D. J. Evans,, E. Galindo,, B. L. Portnoy,, and R. H. Conklin. 1977. Enteropathogens associated with pediatric diarrhea in Mexico City. J. Pediatr. 91: 65– 68.
32. Farkas, T.,, X. Jiang,, M. L. Guerrero,, W. Zhong,, N. Wilton,, T. Berke,, D. O. Matson,, L. K. Pickering,, and G. Ruiz-Palacios. 2000. Prevalence and genetic diversity of human caliciviruses (HuCVs) in Mexican children. J. Med. Virol. 62: 217– 223.
33. Flores-Abuxapqui, J. J.,, G. J. Suarez-Hoil,, M. A. Puc-Franco,, M. R. Heredia-Navarrete,, and J. Franco-Monsreal. 1993. Prevalencia de enteropatogenos en ninos con diarrea liquida. Rev. Latinoam. Microbiol. 35: 351– 356.
34. Gaggero, A.,, M. O’Ryan,, J. S. Noel,, R. I. Glass,, S. S. Monroe,, N. Mamani,, V. Prado,, and L. F. Avendano. 1998. Prevalence of astrovirus infection among Chilean children with acute gastroenteritis. J. Clin. Microbiol. 36: 3691– 3693.
35. Glass, R. I.,, J. Noel,, T. Ando,, R. Fankhauser,, G. Belliot,, A. Mounts,, U. D. Parashar,, J. S. Bresee,, and S. S. Monroe. 2000. The epidemiology of enteric caliciviruses from humans: a reassessment using new diagnostics. J. Infect. Dis. 181( Suppl. 2): S254– S261.
36. Gouet, P.,, M. Contrepois,, H. C. Dubourguier,, Y. Riou,, R. Scherrer,, J. Laporte,, J. F. Vautherot,, J. Cohen,, and R. L’Haridon. 1978. The experimental production of diarrhoea in colostrum deprived axenic and gnotoxenic calves with enteropathogenic Escherichia coli, rotavirus, coronavirus and in a combined infection of rotavirus and E. coli. Ann. Rech. Vet. 9: 433– 440.
37. Graham, D. Y.,, X. Jiang,, T. Tanaka,, A. R. Opekun,, H. P. Madore,, and M. K. Estes. 1994. Norwalk virus infection of volunteers: new insights based on improved assays. J. Infect. Dis. 170: 34– 43.
38. Green, K. Y.,, T. Ando,, M. S. Balayan,, I. N. Clarke,, M. K. Estes,, D. O. Matson,, S. Nakata,, J. D. Neill,, M. J. Studdert,, and H. - J,. Thiel. 2000. Family Caliciviridae, p. 725– 735. In M. H. V. van Regenmortel,, C. M. Fauquet,, D. H. L. Bishop,, E. B. Carstens,, M. K. Estes,, S. M. Lemon,, J. Maniloff,, M. A. Mayo,, D. J. McGeoch,, C. R. Pringle,, and R. B. Wickner (ed.), Virus Taxonomy. Academic Press, San Diego, Calif.
39. Guerrero, M. L.,, J. S. Noel,, D. K. Mitchell,, J. J. Calva,, A. L. Morrow,, J. Martinez,, G. Rosales,, F. R. Velazquez,, S. S. Monroe,, R. I. Glass,, L. K. Pickering,, and G. M. Ruiz- Palacios. 1998. A prospective study of astrovirus diarrhea of infancy in Mexico City. Pediatr. Infect. Dis. J. 17: 723– 727.
40. Hellard, M. E.,, M. I. Sinclair,, G. G. Hogg,, and C. K. Fairley. 2000. Prevalence of enteric pathogens among community based asymptomatic individuals. J. Gastroenterol. Hepatol. 15: 290– 293.
41. Hess, R. G.,, P. A. Bachmann,, G. Baljer,, A. Mayr,, A. Pospischil,, and G. Schmid. 1984. Synergism in experimental mixed infections of newborn colostrum-deprived calves with bovine rotavirus and enterotoxigenic Escherichia coli (ETEC). Zentbl. Vetmed. Reihe B 31: 585– 596.
42. Hori, H.,, P. Akpedonu,, G. Armah,, M. Aryeetey,, J. Yartey,, H. Kamiya,, and M. Sakurai. 1996. Enteric pathogens in severe forms of acute gastroenteritis in Ghanaian children. Acta Pediatr. Jpn. 38: 672– 676.
43. Howard, P.,, N. D. Alexander,, A. Atkinson,, A. O. Clegg,, G. Gerega,, A. Javati,, M. Kajoi,, S. Lupiwa,, T. Lupiwa,, M. Mens,, G. Saleu,, R. C. Sanders,, B. West,, and M. P. Alpers. 2000. Bacterial, viral and parasitic aetiology of paediatric diarrhoea in the highlands of Papua New Guinea. J. Trop. Pediatr. 46: 10– 14.
44. Jackson, S. G.,, R. B. Goodbrand,, R. Ahmed,, and S. Kasatiya. 1995. Bacillus cereus and Bacillus thuringiensis isolated in a gastroenteritis outbreak investigation. Lett. Appl. Microbiol. 21: 103– 105.
45. Jamieson, F. B.,, E. E. L. Wang,, C. Bain,, J. Good,, L. Duckmanton,, and M. Petric. 1998. Human torovirus: a new nosocomial gastrointestinal pathogen. J. Infect. Dis. 178: 1263– 1269.
46. Jay, S.,, F. H. Grau,, K. Smith,, D. Lightfoot,, C. Murray,, and G. R. Davey,. 1997. Salmonella, p. 169– 229. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
47. Jenson, I.,, and C. J. Moir,. 1997. Bacillus cereus and other Bacillus species, p. 379– 406. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
48. Kain, K. C.,, R. L. Barteluk,, M. T. Kelly,, H. Xin,, G. D. Hua,, G. Yuan,, E. M. Proctor,, S. Byrne,, and H. G. Stiver. 1991. Etiology of childhood diarrhea in Beijing, China. J. Clin. Microbiol. 29: 90– 95.
49. Kapikian, A. Z., 1994. Norwalk and Norwalk-like viruses, p. 471– 518. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
50. Kirov, S. M., 1997. Aeromonas, p. 473– 492. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
51. Konkel, M. E.,, and L. A. Joens. 1990. Effect of enteroviruses on adherence to and invasion of HEp-2 cells by Campylobacter isolates. Infect. Immun. 58: 1101– 1105.
52. Koopmans, M. P. G.,, E. S. M. Goosen,, A. A. M. Lima,, I. T. McAuliffe,, J. P. Nataro,, L. J. Barrett,, R. I. Glass,, and R. L. Guerrant. 1997. Association of torovirus with acute and persistent diarrhea in children. Pediatr. Infect. Dis. J. 16: 504– 507.
53. Kurtz, J. B., 1994. Astroviruses, p. 569– 580. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
54. Lam, S.,, S. B. Lim,, M. Yin-Murphy,, and M. Nasir. 1987. Aetiology of diarrhoea in Singapore. Ann. Acad. Med. Singapore 16: 571– 576.
55. Lightfoot, D., 1997. Shigella, p. 465– 472. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
56. Ling, J. M.,, and A. F. Cheng. 1993. Infectious diarrhoea in Hong Kong. J. Trop. Med. Hyg. 96: 107– 112.
57. Marchetti, M.,, M. P. Conte,, C. Longhi,, M. Nicoletti,, L. Seganti,, and N. Orsi. 1992. Effect of enterovirus infection on susceptibility of HeLa cells to Shigella flexneri invasivity. Acta Virol. 36: 443– 449.
58. Marshall, J. A.,, C. J. Birch,, H. G. Williamson,, D. K. Bowden,, C. M. Boveington,, T. Kuberski,, P. H. Bennett,, and I. D. Gust. 1982. Coronavirus-like particles and other agents in the faeces of children in Efate, Vanuatu. J. Trop. Med. Hyg. 85: 213– 215.
59. Marshall, J. A.,, S. Salamone,, L. Yuen,, M. G. Catton,, and P. J. Wright. 2001. High level excretion of Norwalk-like virus following resolution of clinical illness. Pathology 33: 50– 52.
60. Marshall, J. A.,, W. L. Thompson,, and I. D. Gust. 1989. Coronavirus-like particles in adults in Melbourne, Australia. J. Med. Virol. 29: 238– 243.
61. Mata, L.,, A. Simhon,, R. Padilla,, M. D. M. Gamboa,, G. Vargas,, F. Hernandez,, E. Mohs,, and C. Lizano. 1983. Diarrhea associated with rotaviruses, enterotoxigenic Escherichia coli, Campylobacter and other agents in Costa Rican children 1976-1981. Am. J. Trop. Med. Hyg. 32: 146– 153.
62. Meqdam, M. M. M.,, M. T. Youssef,, M. O. Rawashdeh,, and M. S. Al-khdour. 1997. Non-seasonal viral and bacterial episode of diarrhoea in the Jordan Valley, West of Jordan. FEMS Immunol. Med. Microbiol. 18: 133– 138.
63. Modalsli, K.,, G. Bukholm,, and M. Degre. 1990. Coxsackie B1 virus infection enhances the bacterial invasiveness, the phagocytosis and the membrane permeability in HEp-2 cells. APMIS 98: 489– 495.
64. Modalsli, K. R.,, S.-O. Mikalsen,, G. Bukholm,, and M. Degre. 1993. Microinjection of HEp-2 cells with coxsackie B1 virus RNA enhances invasiveness of Shigella flexneri only after prestimulation with UV-inactivated virus. APMIS 101: 602– 606.
65. Monroe, S. S.,, M. J. Carter,, J. E. Herrmann,, J. B. Kurtz,, and S. M. Matsui,. 2000. Family Astroviridae, p. 741– 745. In M. H. V. van Regenmortel,, C. M. Fauquet,, D. H. L. Bishop,, E. B. Carstens,, M. K. Estes,, S. M. Lemon,, J. Maniloff,, M. A. Mayo,, D. J. McGeoch,, C. R. Pringle,, and R. B. Wickner (ed.), Virus Taxonomy. Academic Press, San Diego, Calif.
66. Nataro, J. P.,, and J. B. Kaper. 1998. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11: 142– 201.
67. Nataro, J. P.,, and M. M. Levine,. 1994. Bacterial diarrheas, p. 697– 752. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
68. Newsome, P. M.,, and K. A. Coney. 1985. Synergistic rotavirus and Escherichia coli diarrheal infection of mice. Infect. Immun. 47: 573– 574.
69. Oyofo, B. A.,, R. Soderquist,, M. Lesmana,, D. Subekti,, P. Tjaniadi,, D. J. Fryauff,, A. L. Corwin,, E. Richie,, and C. Lebron. 1999. Norwalk-like virus and bacterial pathogens associated with cases of gastroenteritis onboard a U.S. navy ship. Am. J. Trop. Med. Hyg. 61: 904– 908.
70. Parashar, U. D.,, L. Dow,, R. L. Fankhauser,, C. D. Humphrey,, J. Miller,, T. Ando,, K. S. Williams,, C. R. Eddy,, J. S. Noel,, T. Ingram,, J. S. Bresee,, S. S. Monroe,, and R. I. Glass. 1998. An outbreak of viral gastroenteritis associated with consumption of sandwiches: implications for the control of transmission by food handlers. Epidemiol. Infect. 121: 615– 621.
71. Pollok, R. C. G.,, and M. J. G. Farthing. 2000. Enteric viruses in HIV-related diarrhoea. Mol. Med. Today 6: 483– 487.
72. Runnels, P. L.,, H. W. Moon,, P. J. Matthews,, S. C. Whipp,, and G. N. Woode. 1986. Effects of microbial and host variables on the interaction of rotavirus and Escherichia coli infections in gnotobiotic calves. Am. J. Vet. Res. 47: 1542– 1550.
73. Samuel, S.,, J. Vadivelu,, and N. Parasakthi. 1997. Characteristics of childhood diarrhea associated with enterotoxigenic Escherichia coli in Malaysia. Southeast Asian J. Trop. Med. Public Health 28: 114– 119.
74. Schorling, J. B.,, C. A. Wanke,, S. K. Schorling,, J. F. McAuliffe,, M. A. de Souza,, and R. L. Guerrant. 1990. A prospective study of persistent diarrhea among children in an urban Brazilian slum. Am. J. Epidemiol. 132: 144– 156.
75. Sethi, S. K.,, F. A. Khuffash,, and W. Al- Nakib. 1989. Microbial etiology of acute gastroenteritis in hospitalized children in Kuwait. Pediatr. Infect. Dis. J. 8: 593– 597.
76. Shastri, S.,, A. M. Doane,, J. Gonzales,, U. Upadhyayula,, and D. M. Bass. 1998. Prevalence of astroviruses in a children’s hospital. J. Clin. Microbiol. 36: 2571– 2574.
77. Singh, P. B.,, M. A. Sreenivasan,, and K. M. Pavri. 1989. Viruses in acute gastroenteritis in children in Pune, India. Epidemiol. Infect. 102: 345– 353.
78. Snodgrass, D. R.,, M. L. Smith,, and F. L. Krautil. 1982. Interaction of rotavirus and enterotoxigenic Escherichia coli in conventionally-reared dairy calves. Vet. Microbiol. 7: 51– 60.
79. Soenarto, Y.,, T. Sebodo,, P. Suryantoro,, Krisnomurti,, S. Haksohusodo,, Ilyas,, Kusniyo,, Ristanto,, M. A. Romas,, Noerhajati,, S. Muswiroh,, J. E. Rohde,, N. J. Ryan,, R. K. J. Luke,, G. L. Barnes,, and R. F. Bishop. 1983. Bacteria, parasitic agents and rotaviruses associated with acute diarrhoea in hospital in-patient Indonesian children. Trans. Soc. R. Trop. Med. Hyg. 77: 724– 730.
80. Stanway, G.,, P. Joki-Korpela,, and T. Hyypia. 2000. Human parechoviruses: biology and clinical significance. Rev. Med. Virol. 10: 57– 69.
81. Stewien, K. E.,, E. N. Mos,, R. M. Yanaguita,, J. A. Jerez,, E. L. Durigon,, C. M. Harsi,, H. Tanaka,, R. M. Moraes,, L. A. Silva,, M. A. A. Santos,, J. M. G. Candeias,, K. Tanaka,, T. C. T. Peret,, E. R. Baldacci,, and A. E. Gilio. 1993. Viral, bacterial and parasitic pathogens associated with severe diarrhoea in the city of Sao Paulo, Brazil. J. Diarrhoeal Dis. Res. 11: 148– 152.
82. Superti, F.,, G. Petrone,, S. Pisani,, R. Morelli,, M. G. Ammendolia,, and L. Seganti. 1996. Superinfection by Listeria monocytogenes of cultured human enterocyte-like cells infected with poliovirus or rotavirus. Med. Microbiol. Immunol. 185: 131– 137.
83. Sutherland, P. S.,, and R. J. Porritt,. 1997. Listeria monocytogenes, p. 333– 378. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
84. Szabo, E. A.,, and A. M. Gibson,. 1997. Clostridium botulinum, p. 429– 464. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
85. Taylor, D. N.,, P. Echeverria,, M. J. Blaser,, C. Pitarangsi,, N. Blacklow,, J. Cross,, and B. G. Weniger. 1985. Polymicrobial aetiology of travellers’ diarrhoea. Lancet i: 381– 383.
86. Thouless, M. E.,, R. F. DiGiacomo,, and B. J. Deeb. 1996. The effect of combined rotavirus and Escherichia coli infections in rabbits. Lab. Anim. Sci. 46: 381– 385.
87. Tompkins, D. S.,, M. J. Hudson,, H. R. Smith,, R. P. Eglin,, J. G. Wheeler,, M. M. Brett,, R. J. Owen,, J. S. Brazier,, P. Cumberland,, V. King,, and P. E. Cook. 1999. A study of infectious intestinal disease in England: microbiological findings in cases and controls. Commun. Dis. Public Health 2: 108– 113.
88. Torres-Medina, A. 1984. Effect of combined rotavirus and Escherichia coli in neonatal gnotobiotic calves. Am. J. Vet. Res. 45: 643– 651.
89. Tuazon, C. U., 1995. Other Bacillus species, p. 1890– 1894. In G. L. Mandell,, J. E. Bennett,, and R. Dolin (ed.), Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases, 4th ed. Churchill Livingstone, New York, N.Y.
90. Tzipori, S.,, D. Chandler,, T. Makin,, and M. Smith. 1980. Escherichia coli and rotavirus infections in four-week-old gnotobiotic piglets fed milk or dry food. Aust. Vet. J. 56: 279– 284.
91. Tzipori, S.,, T. Makin,, M. Smith,, and F. Krautil. 1982. Enteritis in foals induced by rotavirus and enterotoxigenic Escherichia coli. Aust. Vet. J. 58: 20– 23.
92. Tzipori, S.,, M. Smith,, C. Halpin,, T. Makin,, and F. Krautil. 1983. Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves. Vet. Microbiol. 8: 35– 43.
93. Tzipori, S. R.,, T. J. Makin,, M. L. Smith,, and F. L. Krautil. 1981. Clinical manifestations of diarrhea in calves infected with rotavirus and enterotoxigenic Escherichia coli. J. Clin. Microbiol. 13: 1011– 1016.
94. Uhnoo, I.,, E. Olding-Stenkvist,, and A. Kreuger. 1986. Clinical features of acute gastroenteritis associated with rotavirus, enteric adenoviruses, and bacteria. Arch. Dis. Child. 61: 732– 738.
95. Ullrich, R.,, W. Heise,, C. Bergs,, M. L’age,, E. O. Riecken,, and M. Zeitz. 1992. Gastrointestinal symptoms in patients infected with human immunodeficiency virus: relevance of infective agents isolated from gastrointestinal tract. Gut 33: 1080– 1084.
96. Unicomb, L. E.,, S. M. Faruque,, M. A. Malek,, A. S. G. Faruque,, and M. J. Albert. 1996. Demonstration of a lack of synergistic effect of rotavirus with other diarrheal pathogens on severity of diarrhea in children. J. Clin. Microbiol. 34: 1340– 1342.
97. Vergara, M.,, M. Quiroga,, S. Grenon,, E. Pegels,, P. Oviedo,, J. Deschutter,, M. Rivas,, N. Binsztein,, and R. Claramount. 1996. Prospective study of enteropathogens in two communities of Misiones, Argentina. Rev. Inst. Med. Trop. Sao Paulo 38: 337– 347.
98. Wadell, G.,, A. Allard,, M. Johansson,, L. Svensson,, and I. Uhnoo,. 1994. Enteric adenoviruses, p. 519– 547. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
99. Wallace, R. B., 1997. Campylobacter, p. 265– 284. In A. D. Hocking,, G. Arnold,, I. Jenson,, K. Newton,, and P. Sutherland (ed.), Foodborne Microorganisms of Public Health Significance, 5th ed. Australian Institute of Food Science and Technology Inc., NSW Branch, Food Microbiology Group, Sydney, New South Wales, Australia.
100. Whipp, S. C.,, H. W. Moon,, L. J. Kemeny,, and R. A. Argenzio. 1985. Effect of virus-induced destruction of villous epithelium on intestinal secretion induced by heat-stable Escherichia coli enterotoxins and prostaglandin E1 in swine. Am. J. Vet. Res. 46: 637– 642.
101. Woode, G. N., 1994. The toroviruses: bovine (Breda virus) and equine (Berne virus) and the torovirus-like agents of humans and animals, p. 581– 602. In A. Z. Kapikian (ed.), Viral Infections of the Gastrointestinal Tract, 2nd ed. Marcel Dekker Inc., New York, N.Y.
102. Wray, C.,, M. Dawson,, A. Afshar,, and M. Lucas. 1981. Experimental Escherichia coli and rotavirus infection in lambs. Res. Vet. Sci. 30: 379– 381.
103. Yamashita, T.,, K. Sakae,, S. Kobayashi,, Y. Ishihara,, T. Miyake,, A. Mubina,, and S. Isomura. 1995. Isolation of cytopathic small round virus (Aichi virus) from Pakistani children and Japanese travelers from Southeast Asia. Microbiol. Immunol. 39: 433– 435.
104. Yamashita, T.,, K. Sakae,, H. Tsuzuki,, Y. Suzuki,, N. Ishikawa,, N. Takeda,, T. Miyamura,, and S. Yamazaki. 1998. Complete nucleotide sequence and genetic organization of Aichi virus, a distinct member of the Picornaviridae associated with acute gastroenteritis in humans. J. Virol. 72: 8408– 8412.
105. Zhang, X. M.,, W. Herbst,, K. G. Kousoulas,, and J. Storz. 1994. Biological and genetic characterization of a hemagglutinating coronavirus isolated from a diarrhoeic child. J. Med. Virol. 44: 152– 161.

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