Source: http://manu19.magtech.com.cn/Jwk_yjhx/CN/abstract/abstract346409.shtml
Timestamp: 2019-04-22 21:58:08+00:00

Document:
Deep eutectic solvent based on L-proline and oxalic acid has been demonstrated for the first time as an efficient catalyst for synthesis of 4,7-dihydro-1H-pyrazolo[3,4-b] pyridine-5-carbonitrile derivatives via one-pot three-component reaction of aldehyde, 3-oxopropanenitrile and 1H-pyrazol-5-amine. The key features of this approach include the broad substrate scope, operational simplicity, recyclable catalyst and possibility to scale up giving multigram quantities.
高歌, 王萍, 刘鹏, 张卫红, 默丽萍, 张占辉. 低共熔溶剂催化一锅合成4,7-二氢-1H-吡唑并[3,4-b]吡啶-5-腈衍生物[J]. 有机化学, 2018, 38(4): 846-854.	Gao Ge, Wang Ping, Liu Peng, Zhang Weihong, Mo Liping, Zhang Zhanhui. Deep Eutectic Solvent Catalyzed One-Pot Synthesis of 4,7-Dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitriles. Chin. J. Org. Chem., 2018, 38(4): 846-854.
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