Source: http://gooa.las.ac.cn/external/index?type=-1&pid=1465248
Timestamp: 2019-04-21 14:54:45+00:00

Document:
M. H. Andrade Santana, M. Chorilli, N. Fachinetti, P. Severino. et al.Process to obtain solid lipid nanoparticles and their use. . DOI: 10.1016/S0939-6411(00)00087-4.
Y. Zhou, N. Wang, T. Wang. Novel preparation method of solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
C. A. D. Paula, A. M. R. Dias, R. A. Heffliger. Nanoscale system for the sustained release of active cosmetic and/or repellent substances. . DOI: 10.1016/S0939-6411(00)00087-4.
Z. Cui, R. J. Mumper. Nanoparticle based vaccine delivery system containing adjuvant. . DOI: 10.1016/S0939-6411(00)00087-4.
W. Ying, R. Adami, Y. Wang, H. Ying. et al.Compositions and methods for nanoparticle lyophile forms. . DOI: 10.1016/S0939-6411(00)00087-4.
C. Singh. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced Ostwald ripening. . DOI: 10.1016/S0939-6411(00)00087-4.
G. Jesudian, J. Gnana, C. Vijaya, I. P. Kaur. et al.Topical tazarotene solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Rodríguez-Gascón, M. A. Solinís Aspiazu, A. Del Pozo-Rodríguez, D. Delgado San Vicente. et al.Lipid nanoparticles for gene therapy. . DOI: 10.1016/S0939-6411(00)00087-4.
P. Burke, M. Gindy, D. Mathre. Preparation of lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
P. R. Vavia, P. R. Wavikar. Solid lipid nanoparticles based formulation of antifungal agent and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
P. A. S. Mandal. Topical gel containing solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Battaglia, M. Trotta, R. Cavalli. Method for the preparation of solid micro and nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
G. D. Gupta. Development of transdermal matrix type patch of diltiazem hydrochloride using solid lipid nanoparticles for arrhythmia. . DOI: 10.1016/S0939-6411(00)00087-4.
V. B. Patravale, P. A. Patel. Lipidic nanoparticles based composition and method of formulation and use thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
Y. Chen, H. Liu, M. J. Pan. External preparation containing sirolimus as well as preparation method and application thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Natarajan, S. Sood, K. Jain, G. Kuppusamy. et al.Solid lipid composition of olanzapine for enhanced oral bioavailability. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Method for producing solid lipid microspheres having a narrow size distribution. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Penkler, R. H. Müller, S. Runge, V. Ravelli. et al.Pharmaceutical cyclosporine formulation with improved biopharmaceutical properties, improved physical quality and greater stability, and method for producing said formulation. . DOI: 10.1016/S0939-6411(00)00087-4.
S. K. Rajput, S. Gullaiya, D. Nagpal. Herbal nanoparticle based targeted drug delivery for alcohol intoxication. . DOI: 10.1016/S0939-6411(00)00087-4.
R. J. Mumper, M. Jay. Microemulsion as precursor to solid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, T. Geetha, K. Meenakshi, B. Gautam. et al.Pharmaceutical topical compositions comprising sesamol solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
K. Na, S.-W. Jin, D. -H. Lee, K. -B. Hahm. et al.Solid lipid nanoparticles for drug delivery, a production method therefor, and injectable preparation comprising the nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, R. Bhandari. Solid lipid nanoparticles entrapping hydrophilic/amphiphilic drug and process for preparing the same. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, G. Sharma, K. Chopra, S. Puri. et al.Process for encapsulating macrobiomolecules in solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, M. K. Verma. Solid nanolipidic particulates of vitamin D3 and retinoic acid. . DOI: 10.1016/S0939-6411(00)00087-4.
J. H. Sun, H. Yuan, F. Liu, S. Q. Chen. et al.Solid lipid magnetic resonance nanoparticles and preparation method and use thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Ghiani, A. Maiocchi, C. Brioschi, M. Visigalli. et al.Paramagnetic solid lipid nanoparticles (PSSLNS) containing metal amphiphilic complexes for MRI. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Jain, R. A. Sonawane, H. P. Harde, M. K. Katariya. et al.A novel submicronic topical formulation for the effective treatment of psoriasis. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco, G. P. Zara, M. F. Saettone. Pharmaceutical compositions suitable for the treatment of ophthalmic diseases. . DOI: 10.1016/S0939-6411(00)00087-4.
A. V. Bhalerao, S. V. Shirolkar. Solid lipid nanoparticle drug delivery system suitable for mucosal delivery. . DOI: 10.1016/S0939-6411(00)00087-4.
N. V. Satheesh Madhav. Carbidopa bio-nanoparticles for brain targeting via ear. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Majumdar, S. K. Samanta, S. Sarkar. Acyclovir loaded solid lipid nanoparticulate gel for topical application and method of formulating the same. . DOI: 10.1016/S0939-6411(00)00087-4.
L. B. Jensen, K. Peterson. A composition comprising lipid nanoparticles and a corticosteroid or vitamin D derivative. . DOI: 10.1016/S0939-6411(00)00087-4.
A. R. Blanco, M. L. Bondì, G. Cavallaro, G. M. L. Consoli. et al.Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases. . DOI: 10.1016/S0939-6411(00)00087-4.
V. T. Kadam, B. K. Nanjwade. Nanostructured lipid carrier drug delivery systems for treatment of neurodegenerative disorders. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Rodríguez-Gascón, M. A. Solinís Aspiazu, A. Del Pozo-Rodríguez, D. Delgado San Vicente. et al.Lipid nanoparticles for trating ocular diseases. . DOI: 10.1016/S0939-6411(00)00087-4.
R. Müller, U. Alexiev, P. Sinambela, C. M. Keck. et al.(2016). Nanostructured lipid carriers (NLC): the second generation of solid lipid nanoparticles. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. DOI: 10.1016/S0939-6411(00)00087-4.
F. Yuan, M. Cao, C. Li, X. Wang. et al.Emamectin benzoate solid lipid nanoparticle, and its preparation method and application in insecticide formulation. . DOI: 10.1016/S0939-6411(00)00087-4.
S. K. Hahn, W. H. Kong, K. Park. Low-density lipoprotein analogue nanoparticles, and composition comprising same for targeted diagnosis and treatment of liver. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Ghiani, A. Maiocchi, L. Caminiti, L. Miragoli. et al.Fluorescent solid lipid nanoprticles composition and preparation thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
F. B. Vanderbist, K. Amighi, G. Pilcer. Improved pharmaceutical dry powder compositions for inhalation. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, M. Yadav. An ocular formulation and a method for its preparation. . DOI: 10.1016/S0939-6411(00)00087-4.
J.-P. Benoit, B. Pitard, P. Saulnier, C. Passirani. et al.Nanocapsules of lipophilic complexes of nucleic acids. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Faure, J. F. M. Voorspoels, R. J. M. Mertens, F. R. I. Kiekens. et al.Process for the preparation of a solid dosage form, in particular a tablet, for pharmaceutical use and process for the preparation of a precursor for a solid dosage form, in particular a tablet. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Kong, W. Pan, J. Liu, W. Zhang. et al.A pharmaceutical nanostructured lipid carrier - IOL System and Its Application. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, K. Krause, K. Mader. . . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Lipid nanoparticles as vehicles for nucleic acids, process for their preparation and use. . DOI: 10.1016/S0939-6411(00)00087-4.
V. E. Babii, A. V. Ignatiev, S. E. Gelperina, O. O. Maksimenko. et al.Pharmaceutical composition for treatment tuberculosis and diseases caused by Helicobacter pylori based on solid lipid nanoparticles and method for tuberculosis treatment. . DOI: 10.1016/S0939-6411(00)00087-4.
M. A. Repka, H. G. Patil, S. Majumdar, J. B. Park. et al.Systems and methods for preparing solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Weiss, C. Maier, A. Kessler, C. Tedeschi. et al.Solid lipid nanoparticles (II). . DOI: 10.1016/S0939-6411(00)00087-4.
N. Passerini, B. Perissutti, B. Albertini, D. Voinovich. et al.(2003). Controlled release of verapamil hydrochloride from waxy microparticles prepared by spray congealing. Journal of Controlled Release.88(2):263-275. DOI: 10.1016/S0939-6411(00)00087-4.
C. Kneuer, C.-M. Lehr, C. Olbrich, R. H. Müller. et al.Transfection complexes (Transoplex) having a reduced toxicity, a higher physical stability, and a higher transfection efficiency, and a method for the production thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
M. Uner, S. Damgali, S. Ozdemir, B. Celik. et al.(2017). Therapeutic potential of drug delivery by means of lipid nanoparticles: reality or illusion?. Current Pharmaceutical Design.23(43):6573-6591. DOI: 10.1016/S0939-6411(00)00087-4.
T.-G. Park, H.-Y. Kim, I.-K. Kim. LDL-like cationic nanoparticles for delivering nucleic acid gene, method for preparing thereof and method for delivering nucleic acid gene using the same. . DOI: 10.1016/S0939-6411(00)00087-4.
B. K. Nanjwade, D. J. Patel, R. A. Udhani, F. V. Manvi. et al.(2011). Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. Scientia Pharmaceutica.79(4):705-727. DOI: 10.1016/S0939-6411(00)00087-4.
P. Severino, T. Andreani, A. S. Macedo, J. F. Fangueiro. et al.(2012). Current state-of-art and new trends on lipid nanoparticles (SLN and NLC) for oral drug delivery. Journal of Drug Delivery.2012-10. DOI: 10.1016/S0939-6411(00)00087-4.
M. Üner, G. Yener. (2007). Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspective. International Journal of Nanomedicine.2(3):289-300. DOI: 10.1016/S0939-6411(00)00087-4.
K. Amighi, T. Sebti. Solid lipid particules as pharmaceutically acceptable fillers or carriers for inhalation. . DOI: 10.1016/S0939-6411(00)00087-4.
R. Cavalli, C. Trotta, M. Trotta. Metodo per la preparazione di micro e nanoparticelle lipidiche. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller. Medicament vehicle for the controlled administration of an active agent, produced from lipid matrix-medicament conjugates. . DOI: 10.1016/S0939-6411(00)00087-4.
L. A. Dellamary, J. Riess, E. G. Schutt, J. G. Weers. et al.Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use. . DOI: 10.1016/S0939-6411(00)00087-4.
J. G. Kim, H. S. Kim, J. H. Cha, A. Alamzeb. et al.Solid lipid nanoparticle composition containing docetaxel for oral administration. . DOI: 10.1016/S0939-6411(00)00087-4.
Q. R. Cao, L. L. Shi, T. Y. Cao, J. H. Cui. et al.Lyophilized preparation of docetaxel solid lipid nanoparticles and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Weiss, C. Maier, B. Leuenberger, M. Novotny. et al.Solid lipid nanoparticles (I). . DOI: 10.1016/S0939-6411(00)00087-4.
S. Kalepu, M. Manthina, V. Padavala. (2013). Oral lipid-based drug delivery systems – an overview. Acta Pharmaceutica Sinica B.3(6):361-372. DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, R. Becker, B. Kruss, K. Peters. et al.Pharmaceutical nanosuspension for medicament administration as systems with increased saturation solubility and speed of dissolution. . DOI: 10.1016/S0939-6411(00)00087-4.
M. Radtke, R. Müller. (2001). Nanostructured lipid drug carriers. New Drugs.2:48-52. DOI: 10.1016/S0939-6411(00)00087-4.
A. Beloqui, M. A. Solinís, A. Rodríguez-Gascón, A. J. Almeida. et al.(2016). Nanostructured lipid carriers: promising drug delivery systems for future clinics. Nanomedicine: Nanotechnology, Biology and Medicine.12(1):143-161. DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, J. S. Lucks. Medication made of solid lipid particles (solid lipid nanospheres - SLN). . DOI: 10.1016/S0939-6411(00)00087-4.
M. D. Del Curto, D. Chicco, P. Esposito. Lipid microparticles by cryogenic micronization. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, E. B. Souto, M. Radtke. Lipid particles on the basis of mixtures of liquid and solid lipids and methods for producing same. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, M. Radtke, S. A. Wissing. (2002). Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Advanced Drug Delivery Reviews.54:S131-S155. DOI: 10.1016/S0939-6411(00)00087-4.
S. A. Wissing, O. Kayser, R. H. Müller. (2004). Solid lipid nanoparticles for parenteral drug delivery. Advanced Drug Delivery Reviews.56(9):1257-1272. DOI: 10.1016/S0939-6411(00)00087-4.
S. Jaspart, G. Piel, L. Delattre, B. Evrard. et al.(2005). Solid lipid microparticles: formulation, preparation, characterisation, drug release and applications. Expert Opinion on Drug Delivery.2(1):75-87. DOI: 10.1016/S0939-6411(00)00087-4.
L. X. Zhang, M. Xue, Z. Z. Jiang. Solid lipid nanoparticles of Tripterygium wilfordii glycosides and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Abraham, V. Mittal, R. Saha, V. Nagpal. et al.Solid lipid nanoparticles of tapentadol. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Shi, T. Zhang. Aripiprazole injection and preparation method therefore. . DOI: 10.1016/S0939-6411(00)00087-4.
S. L. Wang, R. R. Zhu, X. L. He. Application of solid lipid nanoparticles as antidepressant drug carrier. . DOI: 10.1016/S0939-6411(00)00087-4.
H. Lin, S. Zhang, H. Deng, T. Chen. et al.Hydrobromic acid lappaconitine solid lipid nanoparticle and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
C. C. F. Mosqueira, L. T. Oliveira, R. G. Castanheira. Micro- and nanostructured pharmaceutical and veterinary compositions, containing benznidazole and derivatives thereof, which form micro and nanostructures in the gastrointestinal tract, and biologicals uses thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
C. Carbone, S. Cupri, A. Leonardi, G. Puglisi. et al.(2013). Lipid-based nanocarriers for drug delivery and targeting: a patent survey of methods of production and characterization. Pharmaceutical Patent Analyst.2(5):665-677. DOI: 10.1016/S0939-6411(00)00087-4.
C. Carbone, A. Leonardi, S. Cupri, G. Puglisi. et al.(2014). Pharmaceutical and biomedical applications of lipid-based nanocarriers. Pharmaceutical Patent Analyst.3(2):199-215. DOI: 10.1016/S0939-6411(00)00087-4.
A. Garcês, M. H. Amaral, J. M. Sousa Lobo, A. C. Silva. et al.(2018). Formulations based on solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for cutaneous use: a review. European Journal of Pharmaceutical Sciences.112:159-167. DOI: 10.1016/S0939-6411(00)00087-4.
A. D. Mainard, R. J. Aitken, T. Butz, V. Colvin. et al.(2006). Safe handling of nanotechnology. Nature.444(7117):267-269. DOI: 10.1016/S0939-6411(00)00087-4.
L. Rodriguez, C. Cavallari, G. Motta. Apparatus and method for preparing solid forms with controlled release of the active ingredient. . DOI: 10.1016/S0939-6411(00)00087-4.
U. Maasing. Production of lipid-based nanoparticles using a dual asymmetrical centrifuge. . DOI: 10.1016/S0939-6411(00)00087-4.
H. Y. Gao, J. Schwarz, M. Weisspapir. Hybrid lipid-polymer nanoparticulate delivery composition. . DOI: 10.1016/S0939-6411(00)00087-4.
K. Westesen, B. Siekmann. Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
J. L. Soares Sobrinho, S. Melo Tiburcio Cavalcanti Duarte Coelho, M. D. L. S. De Freitas Fernandes Hipolito Reis Dias Rodrigues, C. D. Oliveira De Lacerda Nunes Pinho. et al.Production of lipid nanoparticles by microwave synthesis. . DOI: 10.1016/S0939-6411(00)00087-4.
N. Feng, Y. W. Liu, R. Tan, Z. Chen. et al.Nanostructured lipid carrier, preparation method and application thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Gu, W. Lu, T. Chen, L. Yu. et al.Asiatic acid tromethamine salt lipid nanoparticle preparation and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
R. Pandey, G. K. Khuller. Solid lipid nanoparticles having a drug or drugs encapsulated therein. . DOI: 10.1016/S0939-6411(00)00087-4.
P. Saulnier, J. P. Benoit, S. Anton. Method for preparing lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
C. M. Keck, R. H. Müller. (2013). Nanotoxicological classification system (NCS) – a guide for the risk-benefit assessment of nanoparticulate drug delivery systems. European Journal of Pharmaceutics and Biopharmaceutics.84(3):445-448. DOI: 10.1016/S0939-6411(00)00087-4.
M. Geiser, W. G. Kreyling. (2010). Deposition and biokinetics of inhaled nanoparticles. Particle and Fibre Toxicology.7(1):2. DOI: 10.1016/S0939-6411(00)00087-4.
T. Jun, D. Wang, H. T. Ge, Y. Tao. et al.Solid lipid nanoparticles of finasteride and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
EMA. (2006). Reflection Paper on Nanotechnology-Based Medicinal Products for Human Use. DOI: 10.1016/S0939-6411(00)00087-4.
A. Royere, J. Bibette, D. Bazile. Monodispersed solid lipid particle compositions. . DOI: 10.1016/S0939-6411(00)00087-4.
B. Hertault, P. Saulnier, J. P. Benoit, J.-E. Proust. et al.Lipid nanocapsules, preparation method and use as medicine. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Fatmi, T. K. E. Kim. Methods for enhancing the release and absorption of water insoluble active agents. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Anton, P. Saulnier, J. P. Benoit. Aqueous core lipid nanocapsules for encapsulating hydrophilic and/or lipophilic molecules. . DOI: 10.1016/S0939-6411(00)00087-4.
E. Roger, F. Lagarce, J. P. Benoit. Lipid nanocapsules, method of preparing same, and use thereof as a drug. . DOI: 10.1016/S0939-6411(00)00087-4.
P. E. Galuska, L. M. Rasmussen. Processes for producing lipid particles. . DOI: 10.1016/S0939-6411(00)00087-4.
N. V. Satheesh Madhav. Formulation of tenofovir loaded solid lipid nanoparticles using biolipid from cocoa butter. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, H. Singh. A process for preparation of solid lipid nanoparticles for improving bioavailability of rifampicin. . DOI: 10.1016/S0939-6411(00)00087-4.
U. M. Musazzi, V. Marini, A. Casiraghi, P. Minghetti. et al.(2017). Is the European regulatory framework sufficient to assure the safety of citizens using health products containing nanomaterials?. Drug Discovery Today.22(6):870-882. DOI: 10.1016/S0939-6411(00)00087-4.
M. L. Etheridge, S. A. Campbell, A. G. Erdman, C. L. Haynes. et al.(2013). The big picture on nanomedicine: the state of investigational and approved nanomedicine products. Nanomedicine.9(1):1-14. DOI: 10.1016/S0939-6411(00)00087-4.
A. K. Bansal, K. Vasukumar. Method of improvement of bioavailability of prodrug, using solid lipid nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
N. Wu, B. C. Keller. Lipid drug conjugates for drug delivery. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Hafner, J. Lovric, G. P. Lakos, I. Pepić. et al.(2014). Nanotherapeutics in the EU: an overview on current state and future directions. International Journal of Nanomedicine.9:1005-1023. DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, C. Olbrich. Lipid matrix-drug conjugates particle for controlled release of active ingredient. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Formulations of active principles incorporated in SLNs suitable for transdermal administration. . DOI: 10.1016/S0939-6411(00)00087-4.
G. Dahms, A. Jung, H. Seidel. Compositions for targetted release of fragrances and aromas. . DOI: 10.1016/S0939-6411(00)00087-4.
N. V. Satheesh Madhav. Design of azathioprine solid lipid nanoparticles for colon specificity. . DOI: 10.1016/S0939-6411(00)00087-4.
D. Pandita, A. Ahuja, R. Kakhar, T. Velpandian. et al.A novel modified injection technique for the production of solid lipid nanoprticles for the delivery of paclitaxel. . DOI: 10.1016/S0939-6411(00)00087-4.
M. D. Sabir, S. Amin. Solid lipid nanoparticles as a carrier for lercanidipine, amechanism for two-way enhancement of oral bioavailability. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Nagler. Edelfosine for the treatment of brain tumours. . DOI: 10.1016/S0939-6411(00)00087-4.
G. J. C. B. Gupta, K. R. Jadhav, P. P. S. Pednekar, V. J. Kadam. et al.Solid lipid nanoparticles containing glipizide as effective carrier system for diabetes. . DOI: 10.1016/S0939-6411(00)00087-4.
M. L. G. Bondi, E. F. Craparo, F. Drago. Nanostructured lipid carriers containing riluzole and phamaceutical formulations containing said particles. . DOI: 10.1016/S0939-6411(00)00087-4.
J. C. Cho, C. K. Kang, S. H. Han, E.-D. Son. et al.Composition for skin external use containing omega-3 fatty acid. . DOI: 10.1016/S0939-6411(00)00087-4.
M. Hay, D. W. Thomas, J. L. Craighead, C. Economides. et al.(2014). Clinical development success rates for investigational drugs. Nature Biotechnology.32(1):40-51. DOI: 10.1016/S0939-6411(00)00087-4.
N. Feng, F. Shi, Y. Liu, J. Zhao. et al.Chinese herbal compound antitumour nanopreparation and use thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
D. H. Xu. Method for preparing solid lipid nanoparticles of water-soluble anti-tumor medicine. . DOI: 10.1016/S0939-6411(00)00087-4.
Y.-P. Li, L. L. Chen, W.-W. Gu. Long-circulating solid lipid docetaxel nanoparticles and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
H. Harde, M. Das, S. Jain. (2011). Solid lipid nanoparticles: an oral bioavailability enhancer vehicle. Expert Opinion on Drug Delivery.8(11):1407-1424. DOI: 10.1016/S0939-6411(00)00087-4.
L. Montenegro, A. Campisi, M. G. Sarpietro, C. Carbone. et al.(2011). In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain. Drug Development and Industrial Pharmacy.37(6):737-746. DOI: 10.1016/S0939-6411(00)00087-4.
R. Bodmeier, J. Wang, H. Bhagwatwar. (1992). Process and formulation variables in the preparation of wax microparticles by a melt dispersion technique. I. Oil-in-water technique for water-insoluble drugs. Journal of Microencapsulation.9(1):89-98. DOI: 10.1016/S0939-6411(00)00087-4.
A. Berton, G. Piel, B. Evrard. (2011). Powdered lipid nano and microparticles: production and applications. Recent Patents on Drug Delivery & Formulation.5(3):188-200. DOI: 10.1016/S0939-6411(00)00087-4.
G. Fricker, T. Kromp, A. Wendel, A. Blume. et al.(2010). Phospholipids and lipid-based formulations in oral drug delivery. Pharmaceutical Research.27(8):1469-1486. DOI: 10.1016/S0939-6411(00)00087-4.
S. Weber, A. Zimmer, J. Pardeike. (2014). Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: A review of the state of the art. European Journal of Pharmaceutics and Biopharmaceutics.86(1):7-22. DOI: 10.1016/S0939-6411(00)00087-4.
R. Bodmeier, J. Wang, H. Bhagwatwar. (1992). Process and formulation variables in the preparation of wax microparticles by a melt dispersion technique. II. W/O/W multiple emulsion technique for water-soluble drugs. Journal of Microencapsulation.9(1):99-107. DOI: 10.1016/S0939-6411(00)00087-4.
C. Keck. Compositions containing lipid micro- or nanoparticles for the enhancement of the dermal action of solid particles. . DOI: 10.1016/S0939-6411(00)00087-4.
I. P. Kaur, M. K. Verma. A process for preparing solid lipid sustained release nanoparticles for delivery of vitamins. . DOI: 10.1016/S0939-6411(00)00087-4.
M. D. Del Curto, D. Chicco, M. D’Antonio, V. Ciolli. et al.(2003). Lipid microparticles as sustained release system for a GnRH antagonist (Antide). Journal of Controlled Release.89(2):297-310. DOI: 10.1016/S0939-6411(00)00087-4.
L. Battaglia, L. Serpe, F. Foglietta, E. Muntoni. et al.(2016). Application of lipid nanoparticles to ocular drug delivery. Expert Opinion on Drug Delivery.13(12):1743-1757. DOI: 10.1016/S0939-6411(00)00087-4.
M. Trotta, R. Cavalli, C. Trotta, R. Bussano. et al.(2010). Electrospray technique for solid lipid-based particle production. Drug Development and Industrial Pharmacy.36(4):431-438. DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, M. Lück, J. Kreuter. Medicament excipient particles for tissue specific application of a medicament. . DOI: 10.1016/S0939-6411(00)00087-4.
T. Sebti, K. Amighi. (2006). Preparation and in vitro evaluation of lipidic carriers and fillers for inhalation. European Journal of Pharmaceutics and Biopharmaceutics.63(1):51-58. DOI: 10.1016/S0939-6411(00)00087-4.
Y. Ivri. Solid lipid nanoparticles: Intracochlear drug delivery to the central nervous system. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Microparticles for drug delivery across mucosa and the blood-brain barrier. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Schwarz, M. Weisspapir. Idebenone composition for the treatment of neurological disorders. . DOI: 10.1016/S0939-6411(00)00087-4.
K. Satyavani, T. Ramanathan, S. Gurudeeban, T. Balasubramanian. et al.Drug for treatment of diabetes and diabetic foot ulcer using rutin loaded solid lipid nanoprticles. Treatment of diabetes and diabetic foot ulcer in the form of oral drug, and treatment of diabetic foot ulcer in the form of ointment. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, S. A. Wissing, K. Mäder. UV radiation reflecting or absorbing agents, protecting against harmful UV radiation and reinforcing the natural skin barrier. . DOI: 10.1016/S0939-6411(00)00087-4.
K. Westesen, B. Siekmann. Particles with modified chemical properties, their applications and uses. . DOI: 10.1016/S0939-6411(00)00087-4.
K. Padois, F. Pirot, F. Falson. Solid lipid nanoparticles encapsulating minoxidil and aqueous suspension containing same. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Bertucco, P. Caliceti, N. Elvassore. Process for the production of nanoparticles. . DOI: 10.1016/S0939-6411(00)00087-4.
R. M. Shah, D. S. Eldridge, E. A. Palombo, I. H. Harding. et al.(2017). Microwave-assisted microemulsion technique for production of miconazole nitrate- and econazole nitrate-loaded solid lipid nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics.117:141-150. DOI: 10.1016/S0939-6411(00)00087-4.
P. Chattopadhyay, B. Shekunov, J. Seitzinger, R. Huff. et al.Particles from supercritical fluid extraction of emulsion. . DOI: 10.1016/S0939-6411(00)00087-4.
J. Schwarz, M. Weisspapir. Colloidal solid lipid vehicle for pharmaceutical use. . DOI: 10.1016/S0939-6411(00)00087-4.
S. M. Nazzal, P. W. Sylvester. Tocotrienol composition. . DOI: 10.1016/S0939-6411(00)00087-4.
A. K. Bansal, B. Munjal, S. V. Patel. Self nano-emulsyfiedcurcuminoids composition with en 1hanced bioavailability. . DOI: 10.1016/S0939-6411(00)00087-4.
S. Nunes, A. R. Madureira, D. Campos, B. Sarmento. et al.(2015). Solid lipid nanoparticles as oral delivery systems of phenolic compounds: overcoming pharmacokinetic limitations for nutraceutical applications. Critical Reviews in Food Science and Nutrition.57(9):1863-1873. DOI: 10.1016/S0939-6411(00)00087-4.
S. A. Frautschy, G. M. Cole. Bioavailable curcuminoid formulations for treating Alzheimer’s disease and other age related disorders. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Montenegro. (2017). Lipid-based nanoparticles as carriers for dermal delivery of antioxidants. Current Drug Metabolism.18(5):469-480. DOI: 10.1016/S0939-6411(00)00087-4.
A. J. Almeida, E. Souto. (2007). Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Advanced Drug Delivery Reviews.59(6):478-490. DOI: 10.1016/S0939-6411(00)00087-4.
H. Katarija, J. Prajapati. (2013). The review of patents on solid lipid nanoparticles. Inventi Rapid: NDDS.2013(2):1-3. DOI: 10.1016/S0939-6411(00)00087-4.
C. Charcosset, A. A. El-Harati, H. Fessi. (2005). Preparation of solid lipid nanoparticles using a membrane contactor. Journal of Controlled Release.108(1):112-120. DOI: 10.1016/S0939-6411(00)00087-4.
C. Charcosset, H. Fessi. Novel method for preparing solid lipid nanoparticles using a membrane reactor. . DOI: 10.1016/S0939-6411(00)00087-4.
A. Bot, L. Dellamary, D. Smith, C. M. Woods. et al.Engineered spray dried lipid-based microparticles for cellular targeting. . DOI: 10.1016/S0939-6411(00)00087-4.
N. Anton, J. P. Benoit, P. Saulnier. (2008). Design and production of nanoparticles formulated from nano-emulsion templates—a review. Journal of Controlled Release.128(3):185-199. DOI: 10.1016/S0939-6411(00)00087-4.
X. G. Wang, Y. Chen, J. Huang. Preparation method of catalase solid lipid nanoparticles preparation. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Gastaldi, L. Battaglia, E. Peira, D. Chirio. et al.(2014). Solid lipid nanoparticles as vehicles of drugs to the brain: current state of the art. European Journal of Pharmaceutics and Biopharmaceutics.87(3):433-444. DOI: 10.1016/S0939-6411(00)00087-4.
R. A. Del Pozo, D. Delgado, M. A. Solinis, A. R. Gascon. et al.(2011). Lipid nanoparticles as vehicles for macromolecules: nucleic acids and peptides. Recent Patents on Drug Delivery & Formulation.5:214-226. DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, K. Mäder, S. Gohla. (2000). Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. European Journal of Pharmaceutics and Biopharmaceutics.50(1):161-177. DOI: 10.1016/S0939-6411(00)00087-4.
K. K. Rao. Polymerized solid lipid nanoparticles for oral or mucosal delivery of therapeutic proteins and peptides. . DOI: 10.1016/S0939-6411(00)00087-4.
S. M. T. Cavalcanti, C. Nunes, S. A. Costa Lima, J. L. Soares-Sobrinho. et al.(2018). Optimization of nanostructured lipid carriers for Zidovudine delivery using a microwave-assisted production method. European Journal of Pharmaceutical Sciences.122:22-30. DOI: 10.1016/S0939-6411(00)00087-4.
H. L. Wong, R. Bendayan, A. M. Rauth, Y. Li. et al.(2007). Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. Advanced Drug Delivery Reviews.59(6):491-504. DOI: 10.1016/S0939-6411(00)00087-4.
M. Geszke-Moritz, M. Moritz. (2016). Solid lipid nanoparticles as attractive drug vehicles: composition, properties and therapeutic strategies. Materials Science and Engineering: C.68:982-994. DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco, R. Cavalli, M. E. Carlotti. (1992). Timolol in lipospheres. Die Pharmazie.47(2):119-121. DOI: 10.1016/S0939-6411(00)00087-4.
F. Corrias, F. Lai. (2011). New methods for lipid nanoparticles preparation. Recent Patents on Drug Delivery & Formulation.5(3):201-213. DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Solid lipid nanospheres suitable to a fast internalization into cells. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, N. Grubhofer, C. Olbrich. Stability, biocompatibility optimized adjuvant (SBA) for enhancing humoral and cellular immune response. . DOI: 10.1016/S0939-6411(00)00087-4.
L. Battaglia, M. Gallarate. (2012). Lipid nanoparticles: state of the art, new preparation methods and challenges in drug delivery. Expert Opinion on Drug Delivery.9(5):497-508. DOI: 10.1016/S0939-6411(00)00087-4.
B. X. Xu, Y. Z. Wang, J. Zheng. Cucurbitacin solid lipid nanoparticle preparation and preparation method thereof. . DOI: 10.1016/S0939-6411(00)00087-4.
C. Krysxtof, H. Wosicka. Solid lipid nanoparticles of roxithromycin for hair loss or acne. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, N. Grubhofer, C. Olbrich. Adjuvant which is optimized with regard to stability and biocompatibility (SBA) and which is improved for increasing the humoral and cellular immune responses. . DOI: 10.1016/S0939-6411(00)00087-4.
D. Mishra, D. Dhote, P. Mishra. (2014). Solid lipid nanoparticles: a promising colloidal carrier. Novel Carriers for Drug Delivery:278-301. DOI: 10.1016/S0939-6411(00)00087-4.
C. Mallard, L. Baudonnet. Dermatological compositions comprising avermectin nanocapsules. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco, P. Gasco, A. Bernareggi. Nanoparticle formulations of platinum compounds. . DOI: 10.1016/S0939-6411(00)00087-4.
L. A. Miranda Ferreira, G. Assis Catro Goulart, R. Lambert Orefice, V. T. Lopes Buono. et al.Process to obtain a pharmaceutical composition of retinoids, derivative products of retinoids and its use. . DOI: 10.1016/S0939-6411(00)00087-4.
W. Mehnert, K. Mader. (2001). Solid lipid nanoparticles: production, characterization, and applications. Advanced Drug Delivery Reviews.47(2-3):165-196. DOI: 10.1016/S0939-6411(00)00087-4.
J. P. Benoit, T. Ferrier. Method for preparing functionalized lipid capsules. . DOI: 10.1016/S0939-6411(00)00087-4.
J. L. Viladot Petit, R. Delgado Gonzales, A. Fernandez Botello. Lipid nanoparticles capsules. . DOI: 10.1016/S0939-6411(00)00087-4.
J. P. Benoit, A. Lamprecht. Use of P-glycoprotein inhibitor surfactants at the surface of a colloidal carrier. . DOI: 10.1016/S0939-6411(00)00087-4.
D. Burkhart, J. T. Evans, H. Oberoi, Y. M. Yorgensen. et al.Novel adjuvant formulations. . DOI: 10.1016/S0939-6411(00)00087-4.
P. Chattopadhyay, B. Shekunov, D. Yim, D. Cipolla. et al.(2007). Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system. Advanced Drug Delivery Reviews.59(6):444-453. DOI: 10.1016/S0939-6411(00)00087-4.
S. Salmaso, N. Elvassore, A. Bertucco, P. Caliceti. et al.(2009). Production of solid lipid submicron particles for protein delivery using a novel supercritical gas-assisted melting atomization process. Journal of Pharmaceutical Sciences.98(2):640-650. DOI: 10.1016/S0939-6411(00)00087-4.
L. Battaglia, M. Gallarate, R. Cavalli, M. Trotta. et al.(2010). Solid lipid nanoparticles produced through a coacervation method. Journal of Microencapsulation.27(1):78-85. DOI: 10.1016/S0939-6411(00)00087-4.
M. Dorly del Curto, D. Chicco, P. Esposito. Amphiphilic lipid nanoparticles for peptide and/or protein incorporation. . DOI: 10.1016/S0939-6411(00)00087-4.
C. Olbrich, A. Gessner, O. Kayser, R. H. Müller. et al.(2002). Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate. Journal of Drug Targeting.10(5):387-396. DOI: 10.1016/S0939-6411(00)00087-4.
J. Richard, H. G. Baldascini, R. Agostinetto, L. De Angelis. et al.Solid lipid microcapsules containing growth hormone in the inner solid core. . DOI: 10.1016/S0939-6411(00)00087-4.
M. Gallarate, E. Peira, L. Battaglia. Method for preparing solid lipid nanoparticles containing antibodies in ion pair form using the fatty acid coacervation technique. . DOI: 10.1016/S0939-6411(00)00087-4.
A. D. Miller. (2013). Lipid-based nanoparticles in cancer diagnosis and therapy. Journal of Drug Delivery.2013-9. DOI: 10.1016/S0939-6411(00)00087-4.
L. Battaglia, M. Gallarate, P. P. Panciani, E. Ugazio. et al.(2014). Techniques for the preparation of solid lipid nano and microparticles. Application of nanotechnology in drug delivery. DOI: 10.1016/S0939-6411(00)00087-4.
J. M. Koziara, J. J. Oh, W. S. Akers, S. P. Ferraris. et al.(2005). Blood compatibility of cetyl alcohol/polysorbate-based nanoparticles. Pharmaceutical Research.22(11):1821-1828. DOI: 10.1016/S0939-6411(00)00087-4.
G. P. Vassal, K. Ioulalen, B. C. Brun, N. Lassu. et al.Galenic form under the form of solid lipid particles, useful in pediatrics, comprise temozolomide in lipid matrix, where the matrix comprises triglycerides with saturated fatty acids, and a mixture of fatty acids with specific fatty acids. . DOI: 10.1016/S0939-6411(00)00087-4.
M. R. Gasco. Use of solid lipid nanoparticles comprising cholesteryl propionate and/or cholesteryl butyrate. . DOI: 10.1016/S0939-6411(00)00087-4.
R. H. Müller, M. Radtke, S. A. Wissing. (2002). Nanostructured lipid matrices for improved microencapsulation of drugs. International Journal of Pharmaceutics.242(1-2):121-128. DOI: 10.1016/S0939-6411(00)00087-4.
J. Richard, F. Fais, H. Baldascini. Solid lipid microcapsules containing hGH. . DOI: 10.1016/S0939-6411(00)00087-4.
The traits of lipid biocompatibility and versatility have led to many nano- and microparticulate lipid formulations being engineered, over the last two decades, in the form of spheres and capsules, using solid and liquid lipids as the matrices. This review describes the main types of lipid nano- and microparticles, as well as their preparation methods, administration routes, and main fields of application. It will also provide a synthetic overview of the main patents that have been filed. Patenting activity in the lipid nanoparticle field has been ongoing for 25 years and has been driven by the boom in the use of nanotechnology as an innovative tool for disease treatment and potential commercial interest in a fully biocompatible vehicle. Initially, activity was mainly focused on technological aspects, and later focus shifted more to usage and composition. An increasing number of patents are also being filed by Emerging Countries. However, the most important limitation here is the low number of marketed products, which is mainly caused by regulatory restrictions and economic reasons.

References: V. 
 V. 
 V. 
 V. 
 V. 

V. 

V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V. 
 V.