Source: https://weaverlab.ucsf.edu/publications
Timestamp: 2019-04-19 06:19:54+00:00

Document:
Przybyla, L., J. N. Lakins, R. Sunyer, X. Trepat, and V. M. Weaver, "Monitoring developmental force distributions in reconstituted embryonic epithelia.", Methods, 2015 Sep 2.
Acerbi, I., L. Cassereau, I. Dean, Q. Shi, A. Au, C. Park, Y. Y. Chen, J. Liphardt, E. S. Hwang, and V. M. Weaver, "Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.", Integr Biol (Camb), 2015 May 11.
Cassereau, L., Y. A. Miroshnikova, G. Ou, J. Lakins, and V. M. Weaver, "A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype.", J Biotechnol, vol. 193, pp. 66-9, 2015 Jan 10.
Tung, J. C., M. J Barnes, S. R. Desai, C. Sistrunk, M. W. Conklin, P. Schedin, K. W. Eliceiri, P. J. Keely, V. L. Seewaldt, and V. M. Weaver, "Tumor mechanics and metabolic dysfunction.", Free Radic Biol Med, vol. 79, pp. 269-80, 2015 Feb.
Ou, G., and V. Marie Weaver, "Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells.", Bioessays, vol. 37, issue 12, pp. 1293-7, 2015 Dec.
Northcott, J. M., J. J. Northey, M. J Barnes, and V. M. Weaver, "Fighting the force: Potential of homeobox genes for tumor microenvironment regulation.", Biochim Biophys Acta, vol. 1855, issue 2, pp. 248-253, 2015 Apr.
Rubashkin, M. G., L. Cassereau, R. Bainer, C. C. DuFort, Y. Yui, G. Ou, M. J. Paszek, M. W. Davidson, Y-Y. Chen, and V. M. Weaver, "Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.", Cancer Res, vol. 74, issue 17, pp. 4597-611, 2014 Sep 1.
Pickup, M. W., J. K. Mouw, and V. M. Weaver, "The extracellular matrix modulates the hallmarks of cancer.", EMBO Rep, 2014 Nov 8.
Mouw, J. K., G. Ou, and V. M. Weaver, "Extracellular matrix assembly: a multiscale deconstruction.", Nat Rev Mol Cell Biol, 2014 Nov 5.
Weaver, V. Marie, "The microenvironment matters.", Mol Biol Cell, vol. 25, issue 21, pp. 3254-8, 2014 Nov 1.
Rubashkin, M. G., G. Ou, and V. M. Weaver, "Deconstructing Signaling in 3 Dimensions.", Biochemistry, 2014 Mar 20.
Mouw, J. K., Y. Yui, L. Damiano, R. O. Bainer, J. N. Lakins, I. Acerbi, G. Ou, A. C. Wijekoon, K. R. Levental, P. M. Gilbert, et al., "Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.", Nat Med, 2014 Mar 16.
Paszek, M. J., C. C. DuFort, O. Rossier, R. Bainer, J. K. Mouw, K. Godula, J. E. Hudak, J. N. Lakins, A. C. Wijekoon, L. Cassereau, et al., "The cancer glycocalyx mechanically primes integrin-mediated growth and survival.", Nature, vol. 511, issue 7509, pp. 319-25, 2014 Jul 17.
Shi, Q., R. P. Ghosh, H. Engelke, C. H. Rycroft, L. Cassereau, J. A. Sethian, V. M. Weaver, and J. T. Liphardt, "Rapid disorganization of mechanically interacting systems of mammary acini.", Proc Natl Acad Sci U S A, vol. 111, issue 2, pp. 658-63, 2014 Jan 14.
Venugopalan, G., D. B. Camarillo, K. D. Webster, C. D. Reber, J. A. Sethian, V. M. Weaver, D. A. Fletcher, H. El-Samad, and C. H. Rycroft, "Multicellular architecture of malignant breast epithelia influences mechanics.", PLoS One, vol. 9, issue 8, pp. e101955, 2014.
Maller, O., K. C. Hansen, T. R. Lyons, I. Acerbi, V. M. Weaver, R. Prekeris, A-C. Tan, and P. Schedin, "Collagen architecture in pregnancy-induced protection from breast cancer.", J Cell Sci, vol. 126, issue Pt 18, pp. 4108-10, 2013 Sep 15.
Pickup, M. W., H. Laklai, I. Acerbi, P. Owens, A. E. Gorska, A. Chytil, M. Aakre, V. M. Weaver, and H. L. Moses, "Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas.", Cancer Res, vol. 73, issue 17, pp. 5336-46, 2013 Sep 1.
Tang, Y., G. R Rowe, E. L. Botvinick, A. Kurup, A. J. Putnam, M. Seiki, V. M. Weaver, E. T. Keller, S. Goldstein, J. Dai, et al., "MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.", Dev Cell, vol. 25, issue 4, pp. 402-16, 2013 May 28.
Damiano, L., K. M. Stewart, N. Cohet, J. K. Mouw, J. N. Lakins, J. Debnath, D. Reisman, J. A. Nickerson, A. N. Imbalzano, and V. M. Weaver, "Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.", Oncogene, 2013 Jun 17.
Maller, O., C. C. DuFort, and V. M. Weaver, "YAP forces fibroblasts to feel the tension.", Nat Cell Biol, vol. 15, issue 6, pp. 570-2, 2013 Jun.
Li, C-R., J. J. - M. Su, W-Y. Wang, M. T. - L. Lee, T-Y. Wang, K-Y. Jiang, C-F. Li, J-M. Hsu, C-K. Chen, M. Chen, et al., "Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.", Am J Pathol, vol. 182, issue 2, pp. 363-74, 2013 Feb.
Agus, D. B., J. F. Alexander, W. Arap, S. Ashili, J. E. Aslan, R. H. Austin, V. Backman, K. J. Bethel, R. Bonneau, W-C. Chen, et al., "A physical sciences network characterization of non-tumorigenic and metastatic cells.", Sci Rep, vol. 3, pp. 1449, 2013.
Cassereau, L., C. C. DuFort, and V. M. Weaver, "Morphogenesis: Laying down the tracks.", Nat Mater, vol. 11, issue 6, pp. 490-2, 2012 Jun.
Lu, P., V. M. Weaver, and Z. Werb, "The extracellular matrix: a dynamic niche in cancer progression.", J Cell Biol, vol. 196, issue 4, pp. 395-406, 2012 Feb 20.
Paszek, M. J., C. C. DuFort, M. G. Rubashkin, M. W. Davidson, K. S. Thorn, J. T. Liphardt, and V. M. Weaver, "Scanning angle interference microscopy reveals cell dynamics at the nanoscale.", Nat Methods, vol. 9, issue 8, pp. 825-7, 2012 Aug.
Lakins, J. N., A. R. Chin, and V. M. Weaver, "Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels.", Methods Mol Biol, vol. 916, pp. 317-50, 2012.
Lopez, J. I., I. Kang, W-K. You, D. M. McDonald, and V. M. Weaver, "In situ force mapping of mammary gland transformation.", Integr Biol (Camb), vol. 3, issue 9, pp. 910-21, 2011 Sep.
Dvorak, H. F., V. M. Weaver, T. D. Tlsty, and G. Bergers, "Tumor microenvironment and progression.", J Surg Oncol, vol. 103, issue 6, pp. 468-74, 2011 May 1.
DuFort, C. C., M. J. Paszek, and V. M. Weaver, "Balancing forces: architectural control of mechanotransduction.", Nat Rev Mol Cell Biol, vol. 12, issue 5, pp. 308-19, 2011 May.
Samuel, M. S., J. I. Lopez, E. J. McGhee, D. R. Croft, D. Strachan, P. Timpson, J. Munro, E. Schröder, J. Zhou, V. G. Brunton, et al., "Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth.", Cancer Cell, vol. 19, issue 6, pp. 776-91, 2011 Jun 14.

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