Source: http://www.ojs.ukw.edu.pl/index.php/johs/article/view/2987
Timestamp: 2019-04-24 16:21:43+00:00

Document:
Received: 26.08.2015. Revised 05.09.2015. Accepted: 24.09.2015.
In the article the results of the research of immunological changes after the using of antimicrobial disepidermic cryolyophilized xenoderm grafts in the model of intestinal anastomosis forming; clinical effectiveness of their use for prevention intestinal sutures’ and anastomosis’ insolvency in patients with oncological pathology are presented. In experiment, it is shown, that while using DCXG the essential changes of local immune reactivity have place. It is proved that the tendency of unevenly and not proportionally increasing of cells with main classes Ig A, Ig M, Ig G, Ig E shows highly active and non-stable local immunologic reactions of intestinal mucosa on using DCXG; the intensity of local immune reactions significantly decreases by the 25th day and is nearby to normal ones.
DCXG were used in 50 patients, who underwent surgery in Khmelnytskyi Regional Clinical Oncological Dispensary and Khmelnytskyi Regional Clinical Hospital in 2009–2013 years. The incidence of purulent-inflammatory complications of intestinal anastomosis’ insolvency in the main group of patients was above 4,3 % and 16 % in control one.
Key words: sutures’ insolvency, anastomosis, xenoderm grafts, antimicrobial materials.
sutures’ insolvency, anastomosis, xenoderm grafts, antimicrobial materials.
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