Source: http://revista.rebibio.net/v5n11/v05n11a04a.html
Timestamp: 2019-04-21 04:31:24+00:00

Document:
Quercetin is the most abundant flavonoid and one of the most important antioxidant of plant origin. The aim of the review was to describe quercetin and its role in the prevention and treatment of diseases. Articles were searched from internet databases using the following search words; quercetin, oxidative stress, quercetin and liver disease, quercetin and kidney disease, quercetin and hyperglycemia. The articles that met the selection criteria were used to describe quercetin and its role in the prevention and treatment of different diseases. The result showed that flavonoids are generally found at higher concentrations in outer layers of fruits and vegetables, onion has more quercetin than blackcurrants, broccoli, black grapes and apple. Quercetin and quercetin rich diets are used in the treatment and prevention of hyperglycemia, cardiovascular and kidney diseases, liver damage and nervous system disorders. In conclusion, quercetin is a naturally occurring flavonoid, more abundant in fruits and vegetables and are used in the treatment and prevention of many diseases.
Quercetin; Flavonoid; Oxidative stress; Disease.
Jambhulkar, S.; Deshireddy, S.; Jestadi, D. B.; Periyasamy, L. Quercetin attenuating doxorubicin induced hepatic, cardiac and renal toxicity in male albino Wistar rats. American Journal of Phytomedicine and Clinical Therapeutics, v. 2, p. 985-1004, 2014.
Kawsar, M. H.; Raihana, R.; Sultana, T.; Sohel, D.; Sohaily, S. I. In-vitro and in-vivo models for antioxidant activity evaluation: A review. Journal SUB, v. 5, p. 21-31, 2014.
Kelly, G. S. Quercetin. Alternative Medicine Review, v. 16, p. 172-194, 2011.
Khaleel, E. F.; Mostafa, D. G.; Abdel-Aleem, G. A. Gastroprotective effect of flavonoid quercetin and coenzyme Q10 in indomethacin-induced gastric ulcers in normal and diabetic rats. OSR Journal of Dental and Medical Sciences, v. 14, p. 58-71, 2015.
Kilicarslan, G.; Donmez, N. The effects of quercetin on antioxidant system and some blood parameters in experimental diabetic rats. Bulletin of Environment, Pharmacology and Life Sciences, v. 5, p. 28-32, 2016.
Lombard, K. A.; Geoffriau, E.; Peffley, E. Flavonoid quantification in onion by spectrophotometric and high performance liquid chromatography analysis. HortScience, v. 37, p. 682-685, 2002.
Morris, J. L. Composition and flavonoid levels in Onion (Allium cepa) grown in hydroponies in greenhouses and growth chambers. Texas: Faculty of Texas Technical University, 2001. (M. Sc. Thesis).
Pineda, M. R. B.; Calzada, G. Effect of Philippine red Allium cepa Lin. (Sibuyas na Pula) on serum LDL-cholesterol level. International Journal of Medical and Biomedical Sciences, v. 1, p. 14-20, 2013.
Rajeshkumar, D. Evaluation of antioxidant property and toxicological assessment of Polyalthia longifolia var. Pendula leaf. Saurashtra: Saurashtra University, 2010. (Thesis of doctorate).
Ren, J.; Li, J.; Liu, X.; Feng, Y.; Gui, Y.; Yang, J.; He, W.; Daia, C. Quercetin inhibits fibroblast activation and kidney fibrosis involving the suppression of mammalian target of Rapamycin and β-catenin signaling. Scientific Reports, v. 6, 23968, 2016.
Shakeerabanu, M.; Sujatha, K.; Rajneesh, C. P.; Manimaran, A. The defensive effect of quercetin on indomethacin induced gastric damage in rats. Advances in Biological Research, v. 5, p. 64-70, 2011.
Smith, C.; Lombard, K. A.; Peffley, E. B.; Weixin, L. W. Genetic analysis of quercetin in onion (Allium cepa L.) &apos;Lady Raider&apos;. Texas Journal of Agriculture and Natural Resources, v. 16, p.24-28, 2003.
Trammell, K. W.; Peterson, C. E. Quantitative differences in the flavonol content of yellow onion, Allium cepa L. Journal of the American Society for Horticultural Science, v. 101, p. 205-207, 1976.

References: v. 
 v. 
 v. 
 v. 
 v. 
 v. 
 v. 
 v. 
 v. 
 v. 
 v.