Source: https://stanfordhealthcare.org/doctors/p/marco-perez.html
Timestamp: 2019-04-21 20:14:52+00:00

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Bio: Dr. Marco Perez's research goal is to better understand the fundamental causes of cardiovascular disease through the study of genetics and epidemiology. His group studies the genetic variations and environmental exposures that are associated with conditions such as atrial fibrillation and heart failure. He has led the studies of atrial fibrillation in Women's Health Initiative, one of the largest nation-wide population-based cohorts. He is currently conducting a large study monitoring for silent or asymptomatic atrial fibrillation in women from the WHI randomized to exercise intervention, and is co-PI in the Apple Heart Study, a clinical trial using the Apple Watch to screen for atrial fibrillation. He is interested in understanding the paradox that atrial fibrillation is less common in African Americans and Hispanics, despite a greater burden of risk factors such as hypertension. As director of the Stanford Inherited Arrhythmia Clinic, he evaluates families with rare inherited arrhythmias associated with sudden death such as Long QT and Brugada Syndromes and explores their links with novel genes. He is particularly interested in studying the genetic causes of very early onset atrial fibrillation. He also studies how best to use the electrocardiogram to identify patients at risk for atrial fibrillation and athletes at risk for life-threatening arrhythmias due to conditions such as hypertrophic cardiomyopathy. His genetic studies have led to the discovery of promising novel therapeutic targets that his group is now studying at a functional level. Dr. Perez receives funding from NIH/NHLBI (R01), Apple Inc., the Weston Havens Foundation, The Stanford Cardiovascular Division and the Stanford SPARK program.
Haddad, F., Perez, M., Fleischmann, D., Valantine, H., & Hunt, S. A. (2006). Giant coronary aneurysms in heart transplantation: an unusual presentation of cardiac allograft vasculopathy. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 25(11), 1367–1370.
Perez, M. V., Yaw, T. S., Myers, J., & Froelicher, V. F. (2007). Prognostic value of the computerized ECG in Hispanics. CLINICAL CARDIOLOGY, 30(4), 189–194.
Bravata, D. M., Gienger, A. L., McDonald, K. M., Sundaram, V., Perez, M. V., Varghese, R., … Hlatky, M. A. (2007). Systematic review: The comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery. ANNALS OF INTERNAL MEDICINE, 147(10), 703–U139.
Statin Use and Ventricular Arrhythmias During Clinical Treadmill Testing Dewey, F. E., Perez, M., Hadley, D., Freeman, J. V., Wang, P., Ashley, E. A., … Froelicher, V. F. (2009). Statin Use and Ventricular Arrhythmias During Clinical Treadmill Testing. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 20(2), 193–199.
Added Value of a Resting ECG Neural Network That Predicts Cardiovascular Mortality Perez, M. V., Dewey, F. E., Tan, S. Y., Myers, J., & Froelicher, V. F. (2009). Added Value of a Resting ECG Neural Network That Predicts Cardiovascular Mortality. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 14(1), 26–34.
Isolated Disease of the Proximal Left Anterior Descending Artery Comparing the Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Surgery Kapoor, J. R., Gienger, A. L., Ardehali, R., Varghese, R., Perez, M. V., Sundaram, V., … Bravata, D. M. (2008). Isolated Disease of the Proximal Left Anterior Descending Artery Comparing the Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Surgery. JACC-CARDIOVASCULAR INTERVENTIONS, 1(5), 483–491.
Electrocardiographic predictors of atrial fibrillation Perez, M. V., Dewey, F. E., Marcus, R., Ashley, E. A., Al-Ahmad, A. A., Wang, P. J., & Froelicher, V. F. (2009). Electrocardiographic predictors of atrial fibrillation. AMERICAN HEART JOURNAL, 158(4), 622–628.
Inappropriate pacing in a patient with managed ventricular pacing: What is the cause? Perez, M. V., Al-Ahmad, A. A., Wang, P. J., & Turakhia, M. P. (2010). Inappropriate pacing in a patient with managed ventricular pacing: What is the cause? HEART RHYTHM, 7(9), 1336–1337.
Cost-Effectiveness of Genetic Testing in Family Members of Patients With Long-QT Syndrome Perez, M. V., Kumarasamy, N. A., Owens, D. K., Wang, P. J., & Hlatky, M. A. (2011). Cost-Effectiveness of Genetic Testing in Family Members of Patients With Long-QT Syndrome. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 4(1), 76–84.
The Impact of ST Elevation on Athletic Screening Leo, T., Uberoi, A., Jain, N. A., Garza, D., Chowdhury, S., Freeman, J. V., … Froelicher, V. (2011). The Impact of ST Elevation on Athletic Screening. CLINICAL JOURNAL OF SPORT MEDICINE, 21(5), 433–440.
Catheter ablation of atrial fibrillation: state-of-the-art techniques and future perspectives Santangeli, P., Di Biase, L., Burkhardt, D. J., Horton, R., Sanchez, J., Bai, R., … Al-Ahmad, A. (2012). Catheter ablation of atrial fibrillation: state-of-the-art techniques and future perspectives. JOURNAL OF CARDIOVASCULAR MEDICINE, 13(2), 108–124.
From bedside to bench Perez, M., & Froelicher, V. (2013). From bedside to bench. JOURNAL OF ELECTROCARDIOLOGY, 46(2), 114–115.
Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Perez, M. V., Wang, P. J., Larson, J. C., Soliman, E. Z., Limacher, M., Rodriguez, B., … Stefanick, M. L. (2013). Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Heart , 99(16), 1173–1178.
p300/MDM2 complexes participate in MDM2-mediated p53 degradation Grossman, S. R., Perez, M., Kung, A. L., Joseph, M., Mansur, C., Xiao, Z. X., … Livingston, D. M. (1998). p300/MDM2 complexes participate in MDM2-mediated p53 degradation. MOLECULAR CELL, 2(4), 405–415.
Personalized Medicine and Cardiovascular Disease: From Genome to Bedside Personalized Medicine and Cardiovascular Disease: From Genome to Bedside. (2011). Current Cardiovascular Risk Reports, 5.
Taming Rare Variation With Known Biology in Long QT Syndrome. Perez, M. V., & Ashley, E. A. (2013). Taming Rare Variation With Known Biology in Long QT Syndrome. Circulation. Cardiovascular Genetics, 6(3), 227–229.
Prognostic implications of the J wave ECG patterns. Yong, C. M., Perez, M., & Froelicher, V. (2013). Prognostic implications of the J wave ECG patterns. Journal of Electrocardiology, 46(5), 408–410.
J wave patterns and their prognostic value in African Americans. Perez, M. V., & Froelicher, V. (2013). J wave patterns and their prognostic value in African Americans. Journal of Electrocardiology, 46(5), 442–445.
African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Perez, M. V., Hoffmann, T. J., Tang, H., Thornton, T., Stefanick, M. L., Larson, J. C., … Risch, N. (2013). African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. American Heart Journal, 166(3), 566–572.
Does CHA2DS2-VASc improve stroke risk stratification in postmenopausal women with atrial fibrillation? Abraham, J. E. M., Larson, J., Chung, M. K., Curtis, A. B., Lakshminarayan, K., Newman, J. D., … Wassertheil-Smoller, S. (2013). Does CHA2DS2-VASc improve stroke risk stratification in postmenopausal women with atrial fibrillation? American Journal of Medicine, 126(12), 1143 e1–8.
Use of Medicare data to identify coronary heart disease outcomes in the Women's Health Initiative. Hlatky, M. A., Ray, R. M., Burwen, D. R., Margolis, K. L., Johnson, K. C., Kucharska-Newton, A., … Stefanick, M. L. (2014). Use of Medicare data to identify coronary heart disease outcomes in the Women's Health Initiative. Circulation. Cardiovascular Quality and Outcomes, 7(1), 157–162.
Prevalence and clinical correlates of right ventricular dysfunction in patients with hypertrophic cardiomyopathy. Finocchiaro, G., Knowles, J. W., Pavlovic, A., Perez, M., Magavern, E., Sinagra, G., … Ashley, E. A. (2014). Prevalence and clinical correlates of right ventricular dysfunction in patients with hypertrophic cardiomyopathy. American Journal of Cardiology, 113(2), 361–367.
Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy. Azarbal, F., Singh, M., Finocchiaro, G., Le, V.-V., Schnittger, I., Wang, P., … Perez, M. (2014). Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy. Heart , 100(8), 624–630.
Patterns and prognosis of all components of the J-wave pattern in multiethnic athletes and ambulatory patients. Muramoto, D., Yong, C. M., Singh, N., Aggarwal, S., Perez, M., Ashley, E., … Froelicher, V. (2014). Patterns and prognosis of all components of the J-wave pattern in multiethnic athletes and ambulatory patients. American Heart Journal, 167(2), 259–66.
Different patterns of bundle-branch blocks and the risk of incident heart failure in the Women's Health Initiative (WHI) study. Zhang, Z.-M., Rautaharju, P. M., Soliman, E. Z., Manson, J. A. E., Martin, L. W., Perez, M., … Prineas, R. J. (2013). Different patterns of bundle-branch blocks and the risk of incident heart failure in the Women's Health Initiative (WHI) study. Circulation. Heart Failure, 6(4), 655–661.
Latent obstruction and left atrial size are predictors of clinical deterioration leading to septal reduction in hypertrophic cardiomyopathy. Finocchiaro, G., Haddad, F., Pavlovic, A., Sinagra, G., Schnittger, I., Knowles, J. W., … Ashley, E. (2014). Latent obstruction and left atrial size are predictors of clinical deterioration leading to septal reduction in hypertrophic cardiomyopathy. Journal of Cardiac Failure, 20(4), 236–243.
Electrocardiographic Repolarization-Related Variables as Predictors of Coronary Heart Disease Death in the Women's Health Initiative Study. Rautaharju, P. M., Zhang, Z.-M., Vitolins, M., Perez, M., Allison, M. A., Greenland, P., & Soliman, E. Z. (2014). Electrocardiographic Repolarization-Related Variables as Predictors of Coronary Heart Disease Death in the Women's Health Initiative Study. Journal of the American Heart Association, 3(4).
Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal women. Azarbal, F., Stefanick, M. L., Salmoirago-Blotcher, E., Manson, J. A. E., Albert, C. M., LaMonte, M. J., … Perez, M. V. (2014). Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal women. Journal of the American Heart Association, 3(4).
Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. Seyerle, A. A., Young, A. M., Jeff, J. M., Melton, P. E., Jorgensen, N. W., Lin, Y., … Avery, C. L. (2014). Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. Epidemiology (Cambridge, Mass.), 25(6), 790–8.
P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery Wong, J. K., Lobato, R. L., Pinesett, A., Maxwell, B. G., Mora-Mangano, C. T., & Perez, M. V. (2014). P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 28(6), 1497–1504.
Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval Seyerle, A. A., Young, A. M., Jeff, J. M., Melton, P. E., Jorgensen, N. W., Lin, Y., … Avery, C. L. (2014). Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. EPIDEMIOLOGY, 25(6), 790–798.
Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High-risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY-AF) Turakhia, M. P., Ullal, A. J., Hoang, D. D., Than, C. T., Miller, J. D., Friday, K. J., … Heidenreich, P. A. (2015). Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High-risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY-AF). CLINICAL CARDIOLOGY, 38(5), 285–292.
Pacemaker Therapy in Atrial Fibrillation Park, S., Wang, P. J., Zei, P. C., Hsia, H. H., Turakhi, M., Perez, M. V., & Al-Ahmad, A. A. (2013). Pacemaker Therapy in Atrial Fibrillation. Journal of Cardiology and Vascular Medicine, 1.
Race and ethnicity, obesity, metabolic health, and risk of cardiovascular disease in postmenopausal women. Schmiegelow, M. D., Hedlin, H., Mackey, R. H., Martin, L. W., Vitolins, M. Z., Stefanick, M. L., … Hlatky, M. A. (2015). Race and ethnicity, obesity, metabolic health, and risk of cardiovascular disease in postmenopausal women. Journal of the American Heart Association, 4(5).
Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. Shiffman, D., Perez, M. V., Bare, L. A., Louie, J. Z., Arellano, A. R., & Devlin, J. J. (2015). Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. BMC Cardiovascular Disorders, 15, 104-?
Reply to van Oosten et al: "P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery". Wong, J. K., Maxwell, B. G., & Perez, M. V. (2015). Reply to van Oosten et al: "P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery". Journal of Cardiothoracic and Vascular Anesthesia, 29(5), e63–4.
Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. Shiffman, D., Perez, M. V., Bare, L. A., Louie, J. Z., Arellano, A. R., & Devlin, J. J. (2015). Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. BMC Cardiovascular Disorders, 15(1), 104-?
The associations of leptin, adiponectin and resistin with incident atrial fibrillation in women. Ermakov, S., Azarbal, F., Stefanick, M. L., LaMonte, M. J., Li, W., Tharp, K. M., … Perez, M. V. (2016). The associations of leptin, adiponectin and resistin with incident atrial fibrillation in women. Heart , 102(17), 1354–62.
International criteria for electrocardiographic interpretation in athletes. Drezner, J. A., Sharma, S., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., … Corrado, D. (2017). International criteria for electrocardiographic interpretation in athletes. British Journal of Sports Medicine.
Orexin: a Missing Link Between Sleep Disorders and Heart Failure? Pan, S., Cabral, C. S., Ashley, E. A., & Perez, M. V. (2017). Orexin: a Missing Link Between Sleep Disorders and Heart Failure? Current Heart Failure Reports.
Whole Exome Sequencing in Atrial Fibrillation Lubitz, S. A., Brody, J. A., Bihlmeyer, N. A., Roselli, C., Weng, L.-C., Christophersen, I. E., … Lin, H. (2016). Whole Exome Sequencing in Atrial Fibrillation. PLOS GENETICS, 12(9).
International Recommendations for Electrocardiographic Interpretation in Athletes. Sharma, S., Drezner, J. A., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., … Corrado, D. (2017). International Recommendations for Electrocardiographic Interpretation in Athletes. Journal of the American College of Cardiology, 69(8), 1057–75.
The Associations of Atrial Fibrillation With the Risks of Incident Invasive Breast and Colorectal Cancers Wassertheil-Smoller, S., McGinn, A. P., Martin, L., Rodriguez, B. L., Stefanick, M. L., & Perez, M. (2017). The Associations of Atrial Fibrillation With the Risks of Incident Invasive Breast and Colorectal Cancers. AMERICAN JOURNAL OF EPIDEMIOLOGY, 185(5), 372–84.
Dr. Marco Perez is one of the best physicians I've experienced.
Healthcare all around the world was charged drastically over the last 20 years. People became care providers because they had a passion to help others. As a society we do not take good care of ourselves. The need for good, compassionate healthcare providers is at an all time high but there are to many people pursuing healthcare for a career and not because they have a calling. I live in a small town just under 100,000 people and most of the physicians in Chico, CA treat you like cattle than a person. It's because of these experiences many people, like me, do not seek out answers/care to they're HC problems. I've only had 3 appt. @ Stanford and each time I am there I am treated with dignity and respect. To value me, like this, allows me to relax and trust the system Stanford has in place. Keep it up!
Amazing!!! Hard to describe the level of intelligence, kindness and relatability.
Dr. Perez is an excellent physician. I trust him with my care.
Doctor was excellent and spent plenty of time describing my options for future care.
Dr. Perez listened to my unusual side effects to medication/Toprol XL. He was considerate and obliging to my request to try to get off med & try a heart monitor (Zio monitor).
Dr. Perez always spends plenty of time with us. Never hurries us.
Dr. Perez is a "10"!
Loved Dr. Perez and his team - I felt very comfortable, and like they truly cared.
Dr. Perez was the very best.
I've the highest respect for the care I've been given by Dr. Marco Perez & his NP Allysone Smith. They are both highly skilled, very friendly & caring, and I can't say enough good about them.
Everything was great but I was told I would get a call to go over lab results and I'm still waiting I send an e-mail and have not heard back. I have the results on "my health" but I don't know or understand what it all means.
Dr. Perez is one of the best, most competent, knowledgeable doctors I have ever visited. He has given me excellent care these last close to 2 yrs. I will miss him!
Good experience - doctor was great! Just took too long to get to him as a new pt.
Kate was wonderful again. She carefully explained my condition to me, my progression and further treatment and visits in the future. She really took the time to address my concerns.
I get the best care from Dr. Perez - I call him my miracle worker. He & his staff cured my arrythmia. My heart now beats at regularly.
Dr. Perez has helped me through my ICD process and getting used to it. And answers my questions regarding it.
Love Dr. Perez & his team. Alyson is great.
Dr Perez came to see me and talk to me a number of times when I was in the hospital for a week in July. he is a very compassionate person.
Very impressed with Dr. Perez - - he knew my health history - - it was a 1st of documents to review.
Dr. was very kind and understanding.
Every person I know that wonders how I am I tell Stanford Hosp. is the very best hosp. I have ever been too.
Dr. Perez is also very professional & courteous.
Excellent professional, friendly, knowledgeable, care provider.
Dr. Marco & nurse Alison are very caring and compassionate. Alison is amazing in her quick response times.
Never write on comments BUT Doc Perez and his staff is worth it!
Dr. Perez was excellent in categories.

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