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Fine Needle Aspiration Biopsy (FNAB) in the Diagnosis of Hepatocellular Carcinoma: A Review : Romanian Journal Of Internal Medicine
Department of Cytopathology, Medical School, University of Crete, University Hospital, Heraklion, Crete, Greece
/ Georgios Z. Papadakis
Department of Radiology and Imaging Sciences, National Institutes of Health (NIH), Clinical Center (CC), Bethesda, MD, USA (2)
/ Dimitrios Tamiolakis
/ Iliana Karvela-Kalogeraki
/ Mihailos Karvelas-Kalogerakis
/ John Segredakis
/ Eleni Moustou
Published Online: 2015-10-14 | DOI: https://doi.org/10.1515/rjim-2015-0028
Carcinomul hepatocelular (HCC) este a cincea cauză de malignitate şi a treia cauză de mortalitate prin cancer în întreaga lume. În ciuda progreselor obţinute în tehnicile chirurgicale şi non-chirurgicale pentru tratamentul HCC, există încă controverse privind procedurile diagnostice ale acestei afecţiuni. Pentru a facilita standardizarea procedurilor diagnostic a fost realizat un consens al Asociaţiei Europene pentru studiul bolilor hepatice (European Association for the study of Liver-EASL). Pentru nodulii hepatici cu diametrul mai mare de 2 cm diagnosticul poate fi realizat dacă cel puţin două proceduri imagistice (ecografie, tomografie computerizată, rezonanţă magnetică nucleară sau arteriografia hepatică) demonstrează creşterea vascularizaţiei. Alternativ, nivelurile crescute ale alfa-fetoproteinei alături de o evaluarea imagistică poate transă diagnosticul. Aspiraţie fină pe ac (FNAB) trebuie realizată dacă evaluarea imagistică este indeterminată sau dacă leziunile au diametrele între 1 şi 2 cm. Obiectivul acestei lucrări a fost de a prezenta succint aspectele FNAB pentru diagnosticul HCC.
Keywords: Liver; Hepatocellular carcinoma; FNAB; cytology; immunocytochemistry
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Citation Information: Romanian Journal Of Internal Medicine, ISSN (Online) 1220-4749, DOI: https://doi.org/10.1515/rjim-2015-0028.
© 2015 Alexandra Kalogeraki et al., published by De Gruyter Open. This chapter is distributed under the terms of the Creative Commons Attribution 4.0 Public License. BY 4.0

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