Source: http://research-reports.ucl.ac.uk/RPSDATA.SVC/pubs/waddi73,sbuck68?orderby=year
Timestamp: 2019-04-24 20:09:15+00:00

Document:
Suff, N., Karda, R., Antinao-Diaz, J., Buckley, S.M., Waddington, S.N., Peebles, D.M. (2019). Intrauterine Infection is Associated with a Reduced NFKB Response in Murine Neonatal Developing Brains..
Diaz, J.F.A., Counsell, J.R., Morris, G., Buckley, S.M.K., Davidge, J., Schorge, S., ...Karda, R. (2018). AAV Gene Therapy for Inherited Childhood Epilepsy, Dravet Syndrome.
Hughes, M.P., Smith, D.A., Morris, L., Fletcher, C., Colaco, A., Huebecker, M., ...Henckaerts, E. (2018). AAV9 Intracerebroventricular Gene Therapy Improves Lifespan and Normalises Long-Term Locomotor Behaviour in a Mouse Model of Niemann-Pick Type C1 Disease.
Suff, N., Karda, R., Ng, J., Perocheau, D., Bajaj-Elliott, M., Buckley, S.M.K., ...Peebles, D. (2018). Cervical Gene Delivery of Human Beta-Defensin-3 (HBD-3) Reduces E. coli K1 Ascending Infection and Increases the Proportion of Live Births in Pregnant Mice..
Karda, R., Rahim, A.A., Suff, N., Diaz, J.A., Perocheau, D.P., Martin, N.P., ...Henckaerts, E. (2018). Generation of Light-Producing Somatic-Transgenic Mice Using Adeno-Associated Virus Vector.
Motherwell, W.B., Zard, S.Z. (2018). Preface. PERGAMON-ELSEVIER SCIENCE LTD.
Suff, N., Karda, R., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D., Peebles, D. (2017). A Light-Producing Mouse Model of Ascending Vaginal Infection-Related Preterm Birth..
Delhove, J.M.K.M., Karda, R., Hawkins, K.E., FitzPatrick, L.M., Waddington, S.N., McKay, T.R. (2017). Bioluminescence Monitoring of Promoter Activity In Vitro and In Vivo.. In (pp. 49-64). .
Suff, N., Karda, R., Bajaj-Elliott, M., Tangney, M., Ward, T.H., Peebles, D., ...Waddington, S.N. (2017). Cervical gene delivery of human beta-defensin 3 prevents ascending infection in pregnant mice.
Suff, N., Karda, R., Bajaj-Elliott, M., Buckley, S.M.K., Tangney, M., Waddington, S.N., Peebles, D. (2017). Cervical Gene Delivery of Human Beta-Defensin-3(HBD-3) Prevents Ascending Bacterial Infection in Pregnant Mice..
Ahmed, S.G., Waddington, S.N., Boza-Moran, M.G., Yanez-Munoz, R.J. (2017). Complete Transduction of Spinal Cord Motor Neurons by Intra-Uterine Delivery of Integration-Deficient Lentiviral Vectors.
Karda, R., Karbowniczek, K., Caproni, L., Waddington, S.N., Tite, J. (2017). Creation of lentivirus vectors using novel DNA constructs.
Massaro, G., Perocheau, D., Cuka, S., Hughes, M.P., Baker, R., Karlsson, S., ...Rahim, A.A. (2017). Intravenously administered gene therapy for the treatment of neuronopathic Gaucher Disease.
Counsell, J.R., Vink, C.A., Karda, R., Perocheau, D.P., Brugman, M.H., Buckley, S.M., ...Howe, S.J. (2017). LTR1 Vectors Enhance Safety in Gene Therapy and Can Be Exploited for Rapid, Transient Gene Delivery.
Baruteau, J., Perocheau, D.P., Hanley, J., Rocha-Ferreira, E., Karda, R., Ng, J., ...Prunty, H. (2017). Rescue and Phenotypic Correction in Argininosuccinate Lyase-Deficient Mice by AAV8.ASL Transfer.
Suff, N., Karda, R., Perocheau, D., Delhove, J.M., McKay, T.R., Tangney, M., ...Waddington, S.N. (2016). A Light-Producing Model of Infection-Related Preterm Birth.
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Suff, N. (2016). AAV8-mediated gene therapy rescue of lethal Argininosuccinate lyase-deficient mice..
Karda, R., Buckley, S.M.K., Waddington, S.N. (2016). Gene Therapy with Adeno-associated Virus for Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193 (3), 234-236.
Suff, N., Karda, R., Buckley, S.M.K., Delhove, J.M., McKay, T.R., Tangney, M., ...Peebles, D. (2016). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Infection-Related Preterm Birth..
Karda, R., Perocheau, D.P., Suff, N., Ng, J., Hughes, M., Rahim, A.A., ...Henckaerts, E. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A., ...Martin, N.P. (2016). Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
Karda, R., Perocheau, D.P., Buckley, S.M.K., Delhove, J.M.K.M., Hughes, M., Rahim, A.A., ...Mckay, T.R. (2016). Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors.
Ng, J., Zhen, J., Meyer, E., Erreger, K., Pope, S., Borck, G., ...Waddington, S.N. (2016). Novel therapeutic approaches for childhood parkinsonism.
Migale, R., MacIntyre, D.A., Cacciatore, S., Lee, Y.S., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2016). Relative Contribution of Hormonal and Inflammatory Pathways to Uterine Transcriptome Dynamics in Term and Preterm Labor.
Karda, R., Counsell, J.R., Vink, C.A., Perocheau, D.P., Buckley, S.M.K., Ng, J., ...Howe, S.J. (2016). Transduction of the Central Nervous System with the LTR1 Lentiviral Backbone.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Perocheau, D.P., Rahim, A.A., Rocha-Ferreira, E., ...Hagberg, H.H. (2015). Conscious whole body bioluminescence in somatic-transgenic rodents can be used to quantify and predict brain damage in a mouse model of Cerebral Palsy.
Shangaris, P., Loukogeorgakis, S., Subramanian, S., Blundell, M., Bakhamis, N., Liu, S., ...Urbani, L. (2015). Correction of Haemoglobin Levels in a Humanized Mouse Model of β-thalassemia after Fetal Gene Therapy.
Ng, J., Karda, R., Massaro, G., Meyer, E., Barrel, S., Baruteau, J., ...Kurian, M.A. (2015). Evaluating Promoter Regulated Dopaminergic Neuron Targeting with AAV9 Delivered To the Neonatal Mouse.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Rahim, A.A., Rocha-Ferreira, E., Perocheau, D.P.B., ...Waddington, S.N. (2015). Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy.
Massaro, G., Perocheau, D., Karlsson, S., Cheng, S.H., Waddington, S.N., Rahim, A.A. (2015). Intravenously administered gene therapy for the treatment of neuronopathic Gaucher Disease.
Counsell, J.R., Vink, C.A., Perocheau, D.P.B., Karda, R., Ng, J., Buckley, S.M.K., ...Brugman, M.H. (2015). Novel LTR-1 Lentiviral Vectors Are Fully Functional Following the Removal of HIV-1 Gag-RRE Sequences.
Cuka, S., Ng, J., Seino, K.-.I., Waddington, S.N., Kurian, M.A., Rahim, A.A. (2015). Novel therapeutic strategies in NBIA: A gene therapy approach for PLA2G6-associated.
Delhove, J.M.K.M., Perocheau, D., Buckley, S.M.K., Karda, R., Waddington, S.N., McKay, T.R. (2015). Real-Time Monitoring of Transcription Factor Activity Using In Vitro and In Vivo Models of Cholestasis.
Perocheau, D.P.B., Buckley, S.M.K., Delhove, J.M.K.M., Karda, R., Mckay, T.R., Waddington, S.N. (2015). Use of Somatotransgenic Bioimaging as a Platform for Studying NFkB Pathway in a Tissue-Specific Manner in Two Mouse Models of Inflammation: Rheumatoid Arthritis and Contact Dermatitis.
Hughes, M.P., Howe, S.J., Buckley, S.M., Waddington, S.N., Rahim, A.A. (2014). An evaluation of viral vector-mediated gene delivery to the murine neonatal brain.
Baruteau, J., Hanley, J., Buckley, S.M., Gissen, P., Howe, S.J., Karda, R., ...Rahim, A.A. (2014). Elongation factor 1 alpha as a potential promoter for gene therapy in a murine model of both urea cycle defects and systemic disease: argininosuccinic aciduria.
Rahim, A.A., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., Mills, K., ...Hughes, D.A. (2014). Perinatal gene therapy ameliorates a mouse model of neuronopathic Gaucher disease.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2014). Somatic Transgenesis of the Central Nervous System for Disease Modelling and Treatment. REPRODUCTIVE SCIENCES, 21 (3), 276A-277A.
Buckley, S.M., Delhove, J.M., Karda, R., Perocheau, D., Rahim, A.A., Waddington, S.N., McKay, T.R. (2014). Somatotransgenic Bioimaging: Modelling Disease Progression or Therapeutic Amelioration By Continued Tissue-Specific Bioluminescence Imaging in Living Small Animals.
Migale, R., MacIntyre, D.A., Lee, Y.S., Charalambous, A., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2014). TLR4-Mediated Activation of AP-1 Drives the Expression of Labour Associated Genes in Mouse Myometrium. REPRODUCTIVE SCIENCES, 21 (3), 249A.
Migale, R., MacIntyre, D.A., Lee, Y.S., Charalambous, A., Herbert, B.R., Waddington, S.N., ...Bennett, P.R. (2014). TLR4-mediated activation of AP-1 drives the expression of labour associated genes in mouse myometrium. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121 (7), E10.
Alonso-Ferrero, M.E., Bartolovic, K., Kinnon, C., Mata, M., Waddington, S.N., Milsom, M.D., ...Howe, S.J. (2014). Transient Expression of Genes From Integrative Deficient Lentiviral Vectors Improves Blood Progenitor Cell Expansion, Survival and Engraftment.
Mattar, C.N., Rosales, C., Fragata, R., McIntosh, J., Johana, N., Waddington, S.N., ...Biswas, A. (2013). A robust preclinical model for fetal gene therapy: strategies targeting the liver for molecular correction of congenital single gene defects at early and late gestation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120 5.
Rahim, A.A., Sirka, E., Burke, D.G., Buckley, S.M., Cullen, E., Mukherji, S., ...Hughes, D.A. (2013). In utero gene therapy rescue of an acute neonatal lethal mouse model of neuropathic Gaucher Disease.
Aitchison, K.L., Rahim, A.A., Reed, M., Burke, D.G., Hughes, D.A., Heales, S., ...Howe, S.J. (2013). Lentiviral vectors for gene therapy of type I Gaucher disease.
Karda, R., Delhove, J.M.K.M., Buckley, S.M.K., Ward, N.J., Rahim, A.A., Herbert, B., ...Johnson, M.R. (2013). Somatic transgenesis of the central nervous system for disease modelling and treatment.
Buckley, S.M.K., Delhove, J., Karda, R., Waddington, S.N., McKay, T.R. (2013). Somatotransgenic bioimaging: a novel biosensing platform for in vivo bioimaging.
Herbert, B.R., Hua, R., Waddington, S.N., Sooranna, S.R., Johnson, M.R. (2012). Absence of Maternal CCR2 Reduces the Adverse Effects of LPS-Induced Inflammation on Neonatal Outcome. REPRODUCTIVE SCIENCES, 19 (S3), 120A.
Roybal, J.L., Endo, M., Buckley, S.M.K., Herbert, B.R., Waddington, S.N., Flake, A.W. (2012). Animal models for prenatal gene therapy: rodent models for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 201-218.
David, A.L., Waddington, S.N. (2012). Candidate diseases for prenatal gene therapy.. In (pp. 9-39). .
David, A.L., Waddington, S.N. (2012). Candidate diseases for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 9-39.
Coughlan, L., Waddington, S.N., Buckley, S.M., Campton, J., Custers, J., Nicklin, S.A., Baker, A.H. (2012). CD46 Does Not Affect the In Vivo Biodistribution of Species D Adenoviruses, Ad26 or Ad48 in CD46 Transgenic Mice Following IV Delivery.
Delhove, J.M.K.M., Rahim, A.A., McKay, T.R., Waddington, S.N., Buckley, S.M.K. (2012). Choice of surrogate and physiological markers for prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 273-290.
Aitchison, K.L., Rahim, A.A., Hughes, D., Kinnon, C., Waddington, S.N., Howe, S.J. (2012). Developing lentiviral vectors for gene therapy of Type I Gaucher Disease.
Delhove, J.M.K.M., Waddington, S.N., Ward, N.J., Jathoul, A.P., Pule, M.A., McKay, T.R., Buckley, S.M.K. (2012). Development of bicistronic lentiviral vectors for continual in vivo and endpoint analysis of gene and stem cell transfer.
Rahim, A.A., Wong, A.M., Hofer, K., Buckley, S.M., Mukherji, S., Cooper, J.D., Waddington, S.N. (2012). Intravenous administration of AAV2/9 to fetal and neonatal mice leads to extensive transduction of visceral organs and intestinal epithelia.
Coutelle, C., Waddington, S.N., Themis, M. (2012). Monitoring for potential adverse effects of prenatal gene therapy: mouse models for developmental aberrations and inadvertent germ line transmission.. Methods in molecular biology (Clifton, N.J.), 891 329-340.
Mehta, V., Abi-Nader, K.N., Carr, D., Wallace, J., Coutelle, C., Waddington, S.N., ...David, A.L. (2012). Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application.. In (pp. 291-328). .
Mehta, V., Abi-Nader, K.N., Carr, D., Wallace, J., Coutelle, C., Waddington, S.N., ...David, A.L. (2012). Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application.. Methods in molecular biology (Clifton, N.J.), 891 291-328.
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Waddington, S.N. (2012). Optimised Factor VIII Vectors for Gene Therapy of Haemophilia A.
Rahim, A.A., Wong, A.M., Hoefer, K., Buckley, S.M., Mattar, C.N., Chan, J.K., ...Waddington, S.N. (2012). Systemic Gene Expression after Intravenous Injection of Adeno-Associated Virus 2/9 to Fetal and Neonatal Mice.
Coutelle, C., Waddington, S.N. (2012). The concept of prenatal gene therapy.. Methods in molecular biology (Clifton, N.J.), 891 1-7.
Coutelle, C., Waddington, S.N. (2012). Vector systems for prenatal gene therapy: choosing vectors for different applications.. Methods in molecular biology (Clifton, N.J.), 891 41-53.
Binny, C., McIntosh, J., Peruta, M., Kymalainen, H., Tuddenham, E., Waddington, S., ...Thrasher, A. (2011). AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage. HUMAN GENE THERAPY, 22 (10), A45.
Kao, V.Y.C., Waddington, S.N., Equihua, C.M., Thrasher, A.J., Antoniou, M.N. (2011). Curative F.IX production from low-dose UCOE-lentiviral vectors. HUMAN GENE THERAPY, 22 (10), A110.
Waddington, S.N. (2011). Fetal and neonatal gene therapy. HUMAN GENE THERAPY, 22 (10), A13.
Aitchison, K.L., Rahim, A.A., Hughes, D.A., Kinnon, C., Waddington, S.N., Howe, S.J. (2011). Lentiviral vectors for gene therapy of Type I Gaucher Disease. HUMAN GENE THERAPY, 22 (10), A44.
Ward, N.J., Buckley, S.M.K., Rahim, A.A., McVey, J.H., Thrasher, A.J., Waddington, S.N. (2011). Optimised vectors for the treatment of haemophilia A. HUMAN GENE THERAPY, 22 (10), A109.
McKay, T.R., Rahim, A.A., Buckley, S.M.K., Ward, N.J., Chan, J.K.Y., Howe, S.J., Waddington, S.N. (2011). Perinatal gene transfer to the liver.. CURRENT PHARMACEUTICAL DESIGN, 17 (24), 2528-2541.
Shaw, S.W.S., De Coppi, P., Resca, E., Waddington, S.N., David, A.L. (2011). Prenatal congenic amniotic fluid stem cells have a higher engraftment potential for haematopoiesis than allogenic transplantation.
Rahim, A.A., Wong, A.M.S., Hoefer, K., Buckley, S.M.K., Mattar, C.N., Chan, J.K.Y., ...Waddington, S.N. (2011). Systemic gene expression following intravenous administration of AAV2/9 to fetal and neonatal mice and non-human primates. HUMAN GENE THERAPY, 22 (10), A106-A107.
Hristova, M., Cuthill, D., Zbarsky, V., Acosta-Saltos, A., Wallace, A., Blight, K., ...Waddington, S.N. (2010). Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development.. Glia, 58 (1), 11-28.
Buckley, S.M.K. (2010). An investigation into prenatal gene therapy for cystic fibrosis using intra-amniotic vector application to mouse models..
Shaw, S.W.S., David, A.L., Antoniou, M., Meola, M., Ward, N., De Coppi, P., Waddington, S.N. (2010). Congenic Fetal Delivered Lentivirus UCOE-Luciferase Transduced Amniotic Fluid Stem Cells Preferentially Engraft in the Liver.
Ward, N.J., Buckley, S.M., Waddington, S.N., Nathwani, A.C., Tuddenham, E.G., Kinnon, C., ...McVey, J.H. (2010). Correction of Murine Hemophilia A Using SIN Lentiviral Vectors Expressing Enhanced Human Factor VIII cDNAs.
Rahim, A.A., Wong, A.M., Hoeffer, K., Buckley, S.M., Mattar, C., Chan, J., ...Waddington, S.N. (2010). Efficient CNS, PNS, and Visceral Gene Delivery Following Fetal and Neonatal Intravenous Administration of AAV9.
Herbert, B.R., Sykes, L., Waddington, S.N., Johnson, M.R., Bennett, P.R. (2010). From Lights, Camera, Action!... to No Lights, Camera, and Preterm Labour!.
Al-Allaf, F.A., Coutelle, C., Waddington, S.N., David, A.L., Harbottle, R., Themis, M. (2010). LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress and perspectives.. Int Arch Med, 3 36-.
Waddington, S.N., Rahim, A.A., Mattar, C., Wong, A.M.S., Hoeffer, K., Buckley, S.M.K., ...Chan, J. (2010). Perinatal Gene Therapy for Lethal Genetic Diseases.
Kennea, N.L., Waddington, S.N., Chan, J., O'Donoghue, K., Yeung, D., Taylor, D.L., ...Edwards, A.D. (2009). Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype. 8 (7), 1069-1079.
Rahim, A.A., Wong, A.M., Howe, S.J., Buckley, S.M., costa-Saltos, A.D., Elston, K.E., ...Anderson, P.N. (2009). Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors. Gene Ther., 16 (4), 509-520.
Rahim, A.A., Wong, A.M., Buckley, S.M., Hughes, D.A., Karlsson, S., Cooper, J.D., ...Waddington, S.N. (2009). Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease.
Parker, A.L., Waddington, S.N., Miller, A.M., Buckley, S.M., Nicklin, S.A., McClure, J.D., ...Baker, A.H. (2009). Genome Wide and Micro RNA Profiling of Murine Livers Following Acute Phase Intravenous Delivery of Ad5 Reveals Subsets of Hepatocyte and Kupffer Cell Regulated Genes.
Alba, R., Bradshaw, A.C., Parker, A.L., Bhella, D., Waddington, S.N., Nicklin, S.A., ...McVey, J.H. (2009). Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: Effect of mutagenesis on FX interactions and gene transfer. 114 965-971.
Greig, J.A., Buckley, S.M.K., Waddington, S.N., Parker, A.L., Bhella, D., Pink, R., ...McVey, J.H. (2009). Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35 and Chimeric Ad5/Ad35 Vectors. 17 (10), 1683-1691.
Mattar, C.N., Dighe, N.M., Waddington, S.N., McIntosh, J., Biswas, A., Fisk, N.M., ...Chan, J. (2009). Long-Term Transgene Expression in New-Born Cynomolgus Macaques Following Intra-Uterine Gene Transfer of Self-Complementary AAV.
Ward, N.J., Apolonia, L., Cochrane, M., Buckley, S.M., Waddington, S.N., Nathwani, A.C., ...Thrasher, A.J. (2009). Nonintegrating Lentiviral Vectors for Treatment of Haemophilia B.
Pirianov, G., Waddington, S.N., Lindstrom, T.M., Terzidou, V., Mehmet, H., Bennett, P.R. (2009). The cyclopentone prostaglandin 15d-PGJ2 delays LPS-induced preterm delivery and reduces mortality in the new born mouse. 150 (2), 669-706.
Parker, A.L., Waddington, S.N., Buckley, S.M.K., Custers, J., Havenga, M.J.E., Rooijen, N.V., ...Baker, A.H. (2009). The effect of neutralising sera on factor X-mediated adenoviral serotype 5 gene transfer. 83 (1), 479-483.
Waddington, S.N., Mcvey, J.H., Bhella, D., Parker, A.L., Barker, K., Atoda, K., ...Denby, L. (2008). A critical role for the adenovirus serotype 5 hexon in liver gene transfer.
Parker, A.L., McVey, J.H., Waddington, S.N., Buckley, S.M.K., Francischetti, I.M.B., Monteiro, R.Q., ...Baker, A.H. (2008). An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes.
Rahim, A.A., Waddington, S.N., Wong, A.M.S., Ward, N.J., Elston, K.E., Buckley, S.M.K., ...Thrasher, A.J. (2008). Efficient gene delivery to the adult and fetal central nervous system using pseudotyped non-integrating lentiviral vectors.
Greig, J.A., McVey, J.H., Waddington, S.N., Parker, A.L., Buckley, S.M.K., Havenga, M.J.E., ...Baker, A.H. (2008). Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35.
Waddington, S.N., Buckley, S.M.K., Coutelle, C. (2008). Fetal gene therapy: Intervention in utero. Biochemist, 30 (3), 7-9.
Crossley, R., Waddington, S.N., Howe, S., Buckley, S., Reynolds, L., Sheard, V., ...Mckay, T.R. (2008). Gene delivery of latency ablated TGF-beta 3 regulates dermal wound re-epithelialization in mice and reduces factors associated with scar tissue formation.
Tuddenham, E.G., Ingerslev, J., Norengaard Sorensen, L., Christiansen, K., Mariani, G., Peyvandi, F., ...Chuah, M.K. (2008). Genetic aspects and research development in haemostasis. 14 (s3), 113-118.
Waddington, S.N., Buckley, S.M.K., Nivsarkar, M.S., Coutelle, C. (2008). Immune responses after in utero and neonatal gene transfer. In Herzog, R.W. (Ed.), Gene Therapy Immunology. John Wiley & Sons Inc..
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Bergau, A., Themis, M., MacVinish, L.J., ...Coutelle, C. (2008). Intra-amniotic delivery of CFTR expressing adenovirus does not reverse Cystic Fibrosis phenotype in inbred CFTR-knockout mice.
Buckley, S.M., Howe, S.J., Sheard, V., Ward, N.J., Coutelle, C., Thrasher, A.J., ...McKay, T.R. (2008). Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression. Gene Ther., 15 (16), 1167-1175.
David, A.L., Torondel, B., Zachary, I., Wigley, V., Abi-Nader, K., Mehta, V., ...Rodeck, C.H. (2008). Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep (vol 15, pg 1344, 2008).
David, A.L., Torondel, B., Zachary, I., Wigley, V., Abi Nader, K., Mehta, V., ...Rodeck, C.H. (2008). Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep.. Gene Therapy, 15 1344-1350.
Buckley, S.M., Howe, S.J., Rahim, A.A., Buning, H., McIntosh, J., Wong, S.P., ...Coutelle, C. (2008). Luciferin Detection After Intranasal Vector Delivery Is Improved by Intranasal Rather Than Intraperitoneal Luciferin Administration.. Hum.Gene Ther., 19 (10), 1050-1056.
Ward, N.J., Apolonia, L., Fernandes, C., Waddington, S.N., Cochrane, M., Nathwani, A.C., ...Philpott, N.J. (2008). Non-integrating lentiviral vector pseudotypes for safer gene therapy.
Argyros, O., Wong, S.P., Nicetta, M., Waddington, S.N., Coutelle, C., Miller, A.D., Harbottle, R.P. (2008). Persistent episomal transgene expression in liver following hydrodynamic delivery of S/MAR-Containing plasmid DNA.
Thornhill, S., Grassman, E., Ulaganathan, M., Waddington, S.N., Howe, S.J., Van der Loo, H., ...Williams, D. (2008). Self-inactivating retroviral vectors for gene therapy of SCID-X1.
Hibbitt, O.C., Harbottle, R.P., Waddington, S.N., Bursill, C.A., Coutelle, C., Channon, K.M., Wade-Martins, R. (2007). Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection. 9 (6), 488-497.
Waddington, S.N., Buckley, S.M., David, A.L., Peebles, D.M., Rodeck, C.H., Coutelle, C. (2007). Fetal gene transfer. Curr Opin Mol Ther, 9 432-438.
Buckley, S.M.K., Howe, S.J., Thrasher, A., Baker, A.H., Mckay, T.R., Coutelle, C., Waddington, S. (2007). The route of luciferin administration is a critical determinant of detection of pulmonary and nasal luciferase expression by in vivo bioimaging.
Chan, J., Waddington, S.N., O'Donoghue, K., Kurata, H., Guillot, P.V., Gotherstrom, C., ...Fisk, N.M. (2007). Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse. Stem Cells, 25 (4), 875-884.
Muhle, C., Neuner, A., Park, J., Pacho, F., Jiang, Q., Waddington, S.N., Schneider, H. (2006). Evaluation of prenatal intra-amniotic LAMB3 gene delivery in a mouse model of Herlitz disease. 13 (23), 1665-1676.
David, A.L., Rodeck, C.H. (2006). Gene Therapy. In van Vugt, J.M.G., Shulman, L.P. (Eds.), Prenatal Medicine. New York: Taylor & Francis.
Parker, A.L., Nicol, C.G., Waddington, S.N., Buckley, S.M., Shayakhmetov, D.M., Ni, S.H., ...Nicklin, S.A. (2006). Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors.
David, A.L., Torondel, B., Zachary, I., Ramirez, M.J., Buckley, S.M., Cook, T., ...Peebles, D. (2006). Local delivery of adenovirus VEGF to the uterine arteries increases vessel relaxation and uterine artery blood flow in the sheep.
Parker, A.L., Waddington, S.N., Nicol, C.G., Shayakhmetov, D.M., Buckley, S.M.K., Denby, L., ...McVey, J.H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes in vitro and in vivo. 108 (8), 2554-2561.
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y.H., Al-Allaf, F., ...Holder, M. (2006). Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal mice.
Themis, M., Waddington, S.N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M. (2006). Oncogenesis Following Delivery of Lentiviral Vectors to Fetal and Neonatal Mice.
Bigger, B.W., Siapati, E.K., Mistry, A., Waddington, S.N., Nivsarkar, M.S., Jacobs, L., ...Kemball-Cook, G. (2006). Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. 13 (2), 117-126.
Bigger, B.W., Siapati, E.K., Mistry, A., Waddington, S.N., Nivsarkar, M.S., Jacobs, L., ...Kemball-Cook, G. (2006). Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. Gene Therapy, 13 (2), 117-126.
Sun, X.M., Eden, E.R., Waddington, S.N., Soutar, A.K. (2006). Recombineering of a bacterial artificial chromosome for generation of transgenic mice expressing myc-tagged wild type or mutant (D374Y) human PCSK9.
Nathwani, A.C., Gray, J.T., Ng, C.Y., Zhou, J., Spence, Y., Waddington, S.N., ...Boon-Spijker, M. (2006). Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver.. Blood, 107 (7), 2653-2661.
Thanou, M., Miller, A.D., Waddington, S. (2006). The impact of new genomic technologies: Gene Therapy. In Triggle, D.J., Taylor, J.B. (Eds.), Comprehensive Medicinal Chemistry II. Elsevier Ltd..
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Lawrence, L., Schneider, H., Themis, M., Coutelle, C. (2005). Factors influencing adenovirus-medated airway transduction in fetal mice. 12 (3), 484-492.
Coutelle, C., Themis, M., Waddington, S., Buckley, S., Gregory, L., Nivsarkar, M., ...Rodeck, C. (2005). Fetal gene therapy – first proofs of concept - some adverse effects. 12 (22), 1601-1607.
Coutelle, C., Themis, M., Waddington, S.N., Buckley, S.M., Gregory, L.G., Nivsarkar, M.S., ...Rodeck, C. (2005). Gene Therapy Progress and Prospects: Fetal gene therapy - first proofs of concept - some adverse effects. Gene Therapy, 12 1601-1607.
Waddington, S.N., Kramer, M.G., Hernandez-Alcoceba, R., Buckley, S.M.K., Themis, M., Coutelle, C., Prieto, J. (2005). In Utero Gene Therapy: Current Challenges And Perspectives. 11 (5), 661-676.
Jakob, M., Mühle, C., Park, J., Weiß, S., Waddington, S., Schneider, H. (2005). No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery. 7 (6), 630-637.
Themis, M., Waddington, S.N., Schmitt, M., Von Kalle, C., Wang, Y., Al-Allaf, F., ...Holder, M.V. (2005). Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal and neonatal mice. 12 (4), 763-771.
Themis, M., Bennett, P.R., Mehmet, H., Waddington, S.N., Buckley, S.M. (2005). The development of a mouse model to study the effect of uterine infection on preterm labour and fetal outcome..
Holder, M.V., Waddington, S.N., Gregory, L.G., Kramer, M.G., Prieto, J., Mitrophanous, K., ...Bigger, B.W. (2004). Comparison of gene expression from liver specific promoter/enhancer combinations in the context of a lentiviral backbone.
Hoare, J., Waddington, S., Thomas, H.C., Coutelle, C., McGarvey, M.J. (2004). Complement inhibition rescued mice allowing observation of transgene expression following intraportal delivery of baculovirus in mice. 7 (3), 325-333.
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls. 11 (S1), 92-97.
Waddington, S.N., Kennea, N.L., Buckley, S.M.K., Gregory, L.G., Themis, M., Coutelle, C. (2004). Fetal and neonatal gene therapy: benefits and pitfalls.
Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., Mosley, K.M., ...Lawrence, L. (2004). Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne Muscular Dystrophy.. 11 (14), 1117-1125.
Waddington, S.N., Nivsarkar, M., Mistry, A., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of Haemophilia B in immunocompetent mice by prenatal gene therapy.
Waddington, S.N., Nivsarkar, M.S., Mistry, A.R., Buckley, S.M.K., Kemball-Cook, G., Mosley, K.L., ...Brittan, M. (2004). Permanent phenotypic correction of haemophilia B in immunocompetent mice by prenatal gene therapy.
Gregory, L.G., Waddington, S.N., Holder, M., Mitrophanous, K.A., Buckley, S.M.K., Ellard, F.M., ...Kingsman, S. (2004). Pseudotyped lentiviral vectors: Toward an applicability for in utero treatment of Duchenne Muscular Dystrophy.
Waddington, S.N., Buckley, S.M.K., Bernloehr, C., Bossow, S., Ungerechts, G., Cook, T., ...Neubert, W.J. (2004). Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus. 11 (7), 599-608.
Nivsarkar, M.S., Nathwani, A., Mosley, K., Davies, N., Gregory, L.G., David, A.L., ...Waddington, S.N. (2004). Testosterone induced increase in transgene expression in vivo using Adenoviral Gene Delivery Vectors.
Themis, M., Gregory, L.G., Waddington, S.N., Holder, M.V., Mitrophanous, K.A., Buckley, S.M.K., ...Radcliff, P. (2004). The fetal approach: A novel therapy for the treatment of musculo-skeletal disease.
Peebles, D., Gregory, L.G., David, A., Themis, M., Waddington, S., Knapton, H.J., ...Nivsarkar, M. (2004). Widespread marker gene expression in the airway epithelia of fetal sheep after tracheal application of recombinant adenovirus in utero. 11 (1), 70-78.
Waddington, S.N., Buckley, S.M.K., Cook, T., Gregory, L., Rahim, A., Nivsarkar, M., ...Lauer, U.M. (2003). Fetal gene delivery using first and second generation Sendai virus.
Buckley, S.M.K., Waddington, S.N., Jezzard, S., Themis, M., Colledge, W.H., Coutelle, C. (2003). Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice.
Waddington, S.N., Mitrophanous, K.A., Ellard, F., Buckley, S.M.K., Nivsarkar, M., Lawrence, L., ...Kingsman, S. (2003). Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice. 10 (15), 1234-1240.
David, A.L., Themis, M., Waddington, S.N., Gregory, L., Buckley, S.M.K., Nivsarkar, M., ...Coutelle, C. (2003). The current status and future directions of fetal gene therapy. 7 181-209.
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease - a review. Placenta, 24 S114-S121.
Coutelle, C., Themis, M., Waddington, S., Gregory, L., Nivsarkar, M., Buckley, S., ...David, A. (2003). The hopes and fears of in utero gene therapy for genetic disease--a review. 24 Suppl B S114-S121.
David, A., Cook, T., Waddington, S., Peebles, D., Nivsarkar, M., Knapton, H., ...Schneider, H. (2003). Ultrasound guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero. 14 (4), 353-364.
Gregory, L.G., Peebles, D., David, A., Themis, M., Waddington, S.N., Knapton, H.J., ...Nivsarkar, M. (2003). Widespread and efficient adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in adult mice and fetal sheep after minimally invasive tracheal application.
Waddington, S.N. (2002). Arginase in glomerulonephritis. 61 (3), 876-881.
Schneider, H., Mühle, C., Douar, A.M., Waddington, S., Jiang, Q., Mark, K.V.D., ...Rascher, W. (2002). Sustained delivery of therapeutic concentrations of human clotting factor IX - a comparison of adenoviral and AAV vectors administered in utero. 4 46-53.
Waddington, S.N., Cattell, V. (2000). Arginase in glomerulonephritis.. EXPERIMENTAL NEPHROLOGY, 8 (3), 128-134.
Waddington, S.N., Cattell, V. (1999). Arginase in glomerulonephritis. 2000 (8), 128-134.
Waddington, S.N., Mosley, K., Cattell, V. (1999). Induced nitric oxide (NO) synthesis in heterologous nephrotoxic nephritis; effects of selective inhibition in neutrophil-dependent glomerulonephritis. 118 (2), 309-314.
Mosley, K., Waddington, S.N., Ebrahim, H., Cook, T., Cattell, V. (1999). Inducible nitric oxide synthase induction in thy 1 glomerulonephritis is complement and reactive oxygen species dependent. 7 (1), 26-34.
Cattell, V., Cook, H.T., Ebrahim, H., Waddington, S.N., Wei, X., Assman, K.J.M., Liew, F.Y. (1998). Anti-GBM glomerulonephritis in mice lacking nitric oxide synthase type 2. 53 932-936.
Waddington, S.N., Tam, F.W.K., Cook, H.T., Cattell, V. (1998). Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells. 274 (3), F473-F480.
Waddington, S.N., Mosley, K., Cook, H.T., Tam, F.W.K., Cattell, V. (1998). Arginase AI is upregulated in acute immune complex-induced inflammation. 247 84-87.
Waddington, S., Cook, H.T., Reaveley, D., Jansen, A., Cattell, V. (1996). L-Arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis.. 49 1090-1096.
Elliott, C.J.H., Kemenes, G., Waddington, S. (1991). The modulatory peptide SCPb inhibits feeding in the mollusc Lymnaea stagnalis. 100C (3), 615-618.
Baruteau, J.C.(n.d.).A gene therapy approach for Argininosuccinic aciduria. (Doctoral Dissertation). University College London.

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