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Timestamp: 2019-04-23 02:48:42+00:00

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Physical Data: mp 19.5 °C; bp 76-78 °C/0.17 mmHg.
Solubility: sol CH2Cl2, Et2O, THF, C6H6, MeCN.
Handling, Storage, and Precautions: by analogy to Benzenesulfonyl Chloride, benzenesulfonyl bromide should be assumed to be an irritant and harmful by skin absorption and ingestion. Benzenesulfonyl bromide is best used immediately following preparation and may be used in situ. The reagent is moisture sensitive and will react with nucleophilic solvents (e.g. alcohols), liberating HBr and therefore should be stored under an inert atmosphere. Use in a fume hood.
Protection of Nitrogen; Formation of Sulfonamides.
Benzenesulfonyl bromide reacts readily with trifluoromethanesulfonyl derivatives, yielding the corresponding mixed anhydrides (eq 6)13 which have been used to convert arenes to aryl phenyl sulfones under Friedel-Crafts-type conditions.
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