Source: http://dopovidi-nanu.org.ua/en/archive/2019/1/11
Timestamp: 2019-04-22 16:00:37+00:00

Document:
By the interaction of 2-amino-3,3-dichloroacrylonitrile and chlorosulphonyl isocyanate, (Z)-(5-(dichloromethylene)-2-oxoimidazolidin-4-ylidene)sulfamoyl chloride reacting easily with the excess of an aliphatic amine to form new N-substituted (Z)-N’-(5-(dichloromethylene)-2-oxoimidazolidin-4-ylidene)sulfamides is obtained. According to the National Cancer Institute (USA) examinations, two of the six synthesized amides showed a high anticancer activity.
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