Source: http://www2.riken.jp/nori-tanaka-lab/lab/publications.html
Timestamp: 2019-04-22 11:11:50+00:00

Document:
Tetramethylrhodamine is an essential scaffold of azide probe in detecting cellular acrolein, A. R. Pradipta, M. Fujii, T. Tanei, K. Morimoto, K. Shimazu, S. Noguchi, K. Tanaka, Bioorg. Med. Chem., doi: 10.1016/j.bmc.2019.04.026, (2019).
Chemical sensing of acrolein-amine conjugates for food quality control: A case study of milk products, A. Kishimoto, S. Nomura, K. Tanaka, Bull. Chem. Soc. Jpn., in press (2019).
Efficient route to RIKEN click probes for glycoconjugation, K. Nakamura, K. Tsubokura, A. Kurbangalieva, Y. Nakao, T. Murase, T. Shimoda, K. Tanaka, J. Carbohydr. Chem., doi: 10.1080/07328303.2019.1578886, (2019).
Targeting Bacillus cereus cells: Increasing efficiency of antimicrobials by the bornyl-possessing 2(5H)-furanone derivative, I. S. Sharafutdinov, A. S. Pavlova, A. M. Khabibrakhmanova, R. G. Faizova, A. R. Kurbangalieva, K. Tanaka, E. Y. Trizna, D. R. Baidamshina, M. I. Bogachev, A. R. Kayumov, New Microbiol., 42, 29-36 (2019).
生体内でのパターン認識を可能とする次世代糖鎖クラスター, 小椋章弘, 田中克典, 有機合成化学協会誌, 77, 163-172 (2019).
生体内合成化学治療〜哺乳動物内での有機合成化学が導く未来の医療診断技術〜, 田中克典, MEDCHEM NEWS, 29, 22-28 (2019).
"Click-to-sense" acrolein probe allows highly discriminative, rapid, low-cost and easy-to-perform diagnosis of breast cancer morphology in live tissues, T. Tanei, A. R. Pradipta, K. Morimoto, M. Fujii, J.-I. Ikeda, E. Morii, S. Noguchi, K. Tanaka, Breast J., 44 (S1), S26-S27 (2019).
Influence of Glycosylation Pattern on Protein Biodistribution and Kinetics In Vivo Within Mice, K. Vong, K. Tanaka, In Kinetic Control in Synthesis and Self-Assembly, M. Numata, S. Yagi and T. Hamura (eds), Elsevier, 127-161 (2018).
In vitro and in vivo cancer cell apoptosis triggered by competitive binding of Cinchona alkaloids to the RING domain of TRAF6, Y. Qi, X. Zhao, J. Chen, A. R. Pradipta, J. Wei, H. Ruan, R. P. Hsung, K. Tanaka, L. Zhou, Biosci. Biotechnol. Biochem., doi: 10.1080/09168451.2018.1559030, 1-16 (2018).
A new synthetic route to 5,6,11,12-tetraarylethynyltetracenes, K. Kitamura, K. Asahina, Y. Nagai, K. Zhang, S. Nomura, K. Tanaka, T. Hamura, Org. Biomol. Chem., 16, 9143-9146 (2018).
Glycan Molecular Technology for Highly Selective In Vivo Recognition, K. Tanaka, In Molecular Technology, Life Innovation, Volume 2, H. Yamamoto and T. Kato (eds), Wiley-VCH, 131-163 (2018).
私は有機合成化学者である！ in Message from Young Principal Researcher (MyPR), 田中克典, 有機合成化学協会誌, 76, 1110-1112 (2018).
Synthesis and properties of hydrazine-embedded biphenothiazines and application of hydrazine-embedded heterocyclic compounds to fluorescence cell imaging, Y. Shindo, S. Nomura, Y. Saikawa, M. Nakata, K. Tanaka, K. Hanaya, T. Sugai, S. Higashibayashi, Asian J. Org. Chem., 7, 1797-1801 (2018).
Branched sialylated N-glycans are accumulated in brain synaptosomes and interact with Siglec-H, M. Handa-Narumi, T. Yoshimura, H. Konishi, Y. Fukata, Y. Manabe, K. Tanaka, G.-M. Bao, H. Kiyama, K. Fukase, K. Ikenaka, Cell Struct. Funct., 43, 141-152 (2018).
ラベル化糖鎖を用いた診断とイメージング, 田中克典, 未来を創るグライコサイエンスー我が国のロードマップー, 日本糖質科学コンソーシアム, 189-191 (2018).
Convergent synthesis of a bisecting GlcNAc-containing N-glycan, Y. Manabe, H. Shomura, N. Minamoto, M. Nagasaki, Y. Takakura, K. Tanaka, A. Silipo, A. Molinaro, K. Fukase, Chem. Asian. J., 13, 1544-1551 (2018).
Bis(N,N’-(2-indanolyl))-1,5-diazacyclooctane as Unique Metal Ligand: Self-Assembly of Palladium Nanoparticles and Catalytic Reactivity on C-C Bond Formation, K. Fujiki, K. Tanaka, Synthesis, 50, 1097-1104 (2018).
Therapeutic in vivo synthetic chemistry: exploring on opportunity to activate drugs at specific sites in the body, K. Tsubokura, K. Vong, R. Sibgatullina, A. Kurbangalieva, K. Tanaka, Eur. J. Clin. Invest., 48 (Suppl. 1), 219-220 (2018).
Acrolein detection by in vivo synthetic chemistry: unexplored reactivity of acrolein with azide, A. R. Pradipta, E. Saigitbatalova, A. Kurbangalieva, K. Tanaka, Eur. J. Clin. Invest., 48 (Suppl. 1), 219 (2018).
One-pot three-component double-click method for synthesis of [67Cu]-labeled biomolecular radiotherapeutics, K. Fujiki, S. Yano, T. Ito, Y. Kumagai, Y. Murakami, O. Kamigaito, H. Haba, K. Tanaka, RIKEN Accel. Prog. Rep., 51, 24 (2018).
What is medicinal chemistry? -Demystifying a rapidly evolving discipline!, MedChemComm opinion piece, “What is medicinal chemistry?”, S. Y. L. Holbrook, S. Garneau-Tsodikova, Med. Chem. Commun., 8, 1739-1741 (2017).
中分子創薬のパラダイムシフト：生体内合成化学治療, 田中克典, 文部科学省科学研究費補助金「新学術領域研究」反応集積化が導く中分子戦略：高次生物機能分子の創製ニュースレター, 6, 3 (2017).
Effect of spermine-derived AGEs on oxidative stress and polyamine metabolism, A. Tsutsui, A. R. Pradipta, S. Kitazume, N. Taniguchi, K. Tanaka, Org. Biomol. Chem., 15, 6720-6724 (2017).
Simple Gd3+-Neu5NAc complexation results in NMR chemical shift asymmetries of structurally equivalent complex-type N-glycan branches, K. Usachev, Y. Yamaguchi, M. Takamatsu, N. Pavlova, V. Klochkov, A. Kurbangalieva, T. Murase, T. Shimoda, K. Tanaka, Analyst, 142, 2897-2900 (2017).
Reactivity of anti-HNK-1 antibodies to branched O-mannose glycans associated with demyelination, K. Sakuda, Y. Kizuka, Y. Yamaguchi, K. Tanaka, K. Ogiwara, T. Segawa, Y. Hagiwara, I. Matsuo, H. Ogawa, N. Taniguchi, S. Kitazume, Biochem. Biophys. Res. Commun., 487, 450-456 (2017).
A One-Pot Three-Component Double-Click Method for Synthesis of [67Cu]-Labeled Biomolecular Radiotherapeutics, K. Fujiki, S. Yano, T. Ito, Y. Kumagai, Y. Murakami, O. Kamigaito, H. Haba, K. Tanaka, Sci. Rep., 7, 1912 (2017).
Highly reactive “RIKEN click” probe for glycoconjugation on lysines, R. Sibgatullina, K. Fujiki, T. Murase, T. Yamamoto, T. Shimoda, A. Kurbangalieva, K. Tanaka, Tetrahedron Lett., 58, 1929-1933 (2017).
Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6, Y. Qi, A. R. Pradipta, M. Li, X. Zhao, L. Lu, X. Fu, J. Wei, R. P. Hsung, K. Tanaka, L. Zhou, J. Exp. Clin. Canc. Res., 36, 35 (2017).
Sugar Synthesis by Microfluidic Techniques, K. Fukase, K. Tanaka, Y. Fujimoto, A. Shimoyama, Y. Manabe, In Glycochemical Synthesis: Strategies and Applications, S. -C. Hung, M. M. L. Zulueta (eds), Wiley, DOI: 10.1002/9781119006435.ch8 (2016).
Chemical synthesis of a complex-type N-glycan containing a core fucose, M. Nagasaki, Y. Manabe, N. Minamoto, K. Tanaka, A. Silipo, A. Molinaro, K. Fukase, J. Org. Chem., 81, 10600-10616 (2016).
Progress in the development of reaction-based sensors for detection of acrolein in biological samples, A. R. Pradipta, E. Saigitbatalova, M. Takamatsu, A. Kurbangalieva, K. Tanaka, BioNanoSci., 6, 473-479 (2016).
Unrecognized cycloaddition reactions of N-alkyl-α,β-unsaturated imines occuring in biosystems and their biological roles, A. R. Pradipta, A. Tsutsui, L. Latypova, D. Chulakova, I. Smirnov, A. Kurbangalieva, K. Tanaka, BioNanoSci., 6, 364-367 (2016).
Acrolein Detection by Unrecognized Reactivity of Alkyl Azide, A. R. Pradipta, K. Tanaka, 生体機能関連化学部会ニュースレター, 日本化学会生体機能関連化学部会出版, 31 (2), 9-11 (2016).
Selective C-terminal glycine conjugation based on propargyl ester reactivity, K. K. H. Vong, K. Tanaka, 生体機能関連化学部会ニュースレター, 日本化学会生体機能関連化学部会出版, 31 (1), 6-7 (2016).
アルツハイマー疾患を未然に防ぐ新規な生体内物質の発見, 田中克典, 理研通信サイエンスネット, 56, 1 (2016).
見過ごされていた共役イミンの環化反応：合成的展開と生体機能制御の可能性, A. R. Pradipta, 筒井歩, 田中克典, 有機合成化学協会誌, 74, 700-709 (2016).
Efficient Synthesis of the Disialylated Tetrasaccharide Motif in N-Glycans through an Amide-Protection Strategy,　J. Zhou, Y. Manabe, K. Tanaka, K. Fukase, Chem. Asian. J., 11, 1436-1440 (2016).
First Example of Synthesis of S,O-Macroheterocycle on the basis of 2(5H)-Furanone and 2,2`-Oxydiethanethiol,　A. R. Kurbangalieva, L. T. Hoang, O. A. Lodochnikova, M. Y. Kuzmicheva, A. R. Pradipta, K. Tanaka, G. A. Chmutova, Russ. Chem. Bull. Int. Ed., 5, 1278-1284 (2016).
Glycan multivalency effects toward albumin enable N-glycan-dependent tumor targeting, A. Ogura, T. Tahara, S. Nozaki, H. Onoe, A. Kurbangalieva, Y. Watanabe, K. Tanaka, Bioorg. Med. Chem. Lett., 26, 2251-2254 (2016).
生体内合成化学治療を実現する～動物内で生理活性分子を合成～, 田中克典, Peptide Newsletter Japan, The Japanese Peptide Society 出版, 98, 6-9 (2015).
化学反応による標的タンパク質の同定, 田中克典, 大学院講義 有機化学 第2版, 野依良治編集代表, 株式会社東京化学同人, 352 (2015).
複合領域研究と国際共同研究, 田中克典, 文部科学省科学研究費補助金「新学術領域研究(領域提案型)」天然物ケミカルバイオロジー：分子標的と活性制御ニュースレター, 11, 11 (2015).
Cell surface and in vivo interaction of dendrimeric N-glycoclusters, M. Taichi, S. Kitazume, K. K. H. Vong, R. Imamaki, A. Kurbangalieva, N. Taniguchi, K. Tanaka, Glycoconj. J., 32, 497-503 (2015).
分子イメージングによる糖鎖複合体の動態解析, 深瀬浩一, 田中克典, 下山敦史, 日本分子イメージング学会機関誌 JSMI report, 8, 18-25 (2015).
第11章 クロマトグラフィーによる分析と分取, 土川博史, 田中克典, 有機合成実験法ハンドブック 第２版, 公益社団法人有機合成化学協会監修, 丸善出版株式会社, 61-90 (2015).
第12章 機器分析による分析, 土川博史, 難波康祐, 中尾佳亮, 田中克典, 有機合成実験法ハンドブック 第２版, 公益社団法人有機合成化学協会監修, 丸善出版株式会社, 91-123 (2015).
第4編 糖鎖合成-合成手法　第1章 4-1. 固相合成, 田中克典, 「糖鎖の新機能開発・応用ハンドブック～創薬・医療から食品開発まで」, 秋吉一成監修, （株）エヌ・ティー・エス, 316-321 (2015).
第5編 メディカルサイエンスと糖鎖　第3章1. 糖鎖イメージング, 野崎聡, 田中克典, 深瀬浩一, 渡辺恭良, 「糖鎖の新機能開発・応用ハンドブック～創薬・医療から食品開発まで」, 秋吉一成監修, （株）エヌ・ティー・エス, 461-464 (2015).
PET Imaging of Glycoconjugates, K. Tanaka, In Glycoscience: Biology and Medicine, T. Endo, P. H. Seeberger, G. W. Hart, C.-H. Wong, N. Taniguchi (eds), Springer, 485-490 (2015).
Chemical Glycan Conjugation Controls the Biodistribution and Kinetics of Proteins in Live Animals, A. Ogura, A. Kurbangalieva, K. Tanaka, Mini Rev. Med. Chem., 14, 1072-1077 (2014).
Imino [4+4] cycloaddition products as exclusive and biologically relevant acrolein-amine conjugates are intermediates of 3-formyl-3,4-dehydropiperidine (FDP), an acrolein biomarker, M. Takamatsu, K. Fukase, A. Kurbangalieva, K. Tanaka, Bioorg. Med. Chem., 22, 6380-6386 (2014).
生体内合成化学治療を実現する～動物内で生理活性分子を全合成～, 田中克典, 生命化学研究レター「研究紹介」, フロンティア生命化学研究会出版, 46, 15-20 (2014).
アザ電子環状反応, Staudinger Ligation, 深瀬浩一, 田中克典, ファインケミカルシリーズ「クリックケミストリー -基礎から実用まで-」, 高田十志和, 小山靖人, 深瀬浩一監修, 株式会社シーエムシー出版, 第23章 (2014).
Interaction of platelet endothelial cell adhesion molecule (PECAM) with α 2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role, S. Kitazume, R. Imamaki, A. Kurimoto, K. Ogawa, M. Kato, Y. Yamaguchi, K. Tanaka, H. Ishida, H. Ando, M. Kiso, N. Hashii, N. Kawasaki, N. Taniguchi, J. Biol. Chem., 289, 27604-27613 (2014).
Microfluidic mixing of polyamine with acrolein enables the detection of the [4+4] polymerization of intermediary unsaturated imines: The properties of a cytotoxic 1,5-diazacyclooctane hydrogel, A. R. Pradipta, A. Tsutsui, A. Ogura, S. Hanashima, Y. Yamaguchi, A. Kurbangalieva, K. Tanaka, Synlett, 2442-2446 (2014).
金属触媒を用いた細胞内有機化学反応, 小椋章弘, 有機合成化学協会誌, 72, 726-727 (2014).
Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: A previously unrecognized mechanism for acrolein-mediated oxidative stress, A. Tsutsui, R. Imamaki, S. Kitazume, S. Hanashima, Y. Yamaguchi, M. Kaneda, S. Oishi, N. Fujii, A. Kurbangalieva, N. Taniguchi, K. Tanaka, Org. Biomol. Chem., 12, 5151-5157 (2014).
金属触媒を用いた生細胞内での有機合成反応：生体内での時空間的な糖鎖複合化実現への希望, Metal-catalized Organic Reaction in Live Cell: Future Prospect of Time- and Space-selective Glycan Conjugation In Live Systems, A. Ogura, A. Kurbangalieva, K. Tanaka, Trends Glycosci. Glycotechnol., 26, 73-75 (2014).
In Vivo Kinetics and Biodistribution Analysis of Neoglycoproteins: Effects of Chemically Introduced Glycans on Proteins, A. Ogura, A. Kurbangalieva, K. Tanaka, Glycoconj. J., 31, 273-279 (2014).
Direct Guanylation of Amino Groups by Cyanamide in Water: Catalytic Generation and Activation of Unsaturated Carbodiimide by Sc(OTf)3, K. Tsubokura, T. Iwata, M. Taichi, A. Kurbangalieva, K. Fukase, Y. Nakao, K. Tanaka, Synlett, 1302-1306 (2014).
Template-assisted synthesis of phosphorylated protein recognition peptide and its selective tumor growth inhibition, K. Fukase, T. Iwata, S. Shirotsuki, C. Kageyama, T. Tahara, S. Nozaki, E. R. O. Siwu, S. Tamura, S. Douke, N. Murakami, H. Onoe, Y. Watanabe, K. Tanaka, Peptide Science, 2013, 43-46 (2014).
天然物合成におけるマイクロフロー反応の活用：免疫活性物質, プリスタン天然物のプロセス合成を例として, 田中克典, ファインケミカル「特集 天然物合成化学の新たな展開」, 田中克典監修, 株式会社シーエムシー出版, 23-29 (2014).
ファインケミカル「特集 天然物合成化学の新たな展開」, 田中克典監修, 株式会社シーエムシー出版, 5 (2014).
Facile Preparation of 1,5-Diazacyclooctanes from Unsaturated Imines: Effects of the Hydroxyl Groups on [4+4] Dimerization, K. Tanaka, R. Matsumoto, A. R. Pradipta, Y. Kitagawa, M. Okumura, Y. Manabe, K. Fukase, Synlett, 1026-1030 (2014).
Practical and efficient method for α-sialylation with an azide sialyl donor using a microreactor, Y. Uchinasi, K. Tanaka, Y. Manabe, Y. Fujimoto, K. Fukase, J. Carbohydr. Chem., 33, 55-67 (2014).
A cascading reaction sequence involving ligand-directed azaelectrocyclization and autooxidation-induced fluorescence recovery enables visualization of target proteins on the surfaces of live cells, K. Tanaka, M. Kitadani, A. Tsutsui, A. R. Pradipta, R. Imamaki, S. Kitazume, N. Taniguchi, K. Fukase, Org. Biomol. Chem., 12, 1412-1418 (2014).
Development of Bis-unsaturated Ester Aldehydes as Amino-glue Probes: Sequential Double Azaelectrocyclization as Promising Strategy for Bioconjugation, K. Tanaka, Y. Nakamoto, E. R. O. Siwu, A. R. Pradipta, K. Morimoto, T. Fujiwara, S. Yoshida, T. Hosoya, Y. Tamura, G. Hirai, M. Sodeoka, K. Fukase, Org. Biomol. Chem., 11, 7326-7333 (2013).
2,6,9-Triazabicyclo[3.3.1]nonanes as Overlooked Amino-modification Products by Acrolein, A. Tsutsui, K. Tanaka, Org. Biomol. Chem., 11, 7208-7211 (2013).
動物個体内における糖鎖複合体の分子イメージング, 田中克典, 深瀬浩一, 第三の生命鎖　糖鎖の機能と疾患 （実験医学増刊）, 株式会社羊土社出版, 31, 176-185 (2013).
Synthesis of 3,7,9- and 2,6,9- Triazabicyclo[3.3.1]nonane Derivatives, A. R. Pradipta, K. Tanaka, Heterocycles, 87, 2001-2014 (2013).
Chemical Approach to A Whole Body Imaging of Sialo-N-linked Glycans, K. Tanaka, K. Fukase, In Topics in Current Chemistry volumes, SialoGlyco Chemistry and Biology, R. Gerardy-Schahn, P. Delannoy, and M. von Itzstein (eds), Springer, in press (2013).
論文紹介・気になった論文, A. R. Pradipta, 生命化学研究レター, フロンティア生命化学研究会出版, 41, 21-23 (2013).
Whole-Body Imaging of Tumor Cells by Azaelectrocyclization: Visualization of Metastasis Dependence on Glycan Structure, K. Tanaka, K. Moriwaki, S. Yokoi, K. Koyama, E. Miyoshi, K. Fukase, Bioorg. Med. Chem., 21, 1074-1077 (2013).
Efficient Synthesis of 2,6,9-Triazabicyclo[3.3.1]nonanes through Amine-Mediated Formal [4+4] Reaction of Unsaturated Imines, K. Tanaka, E. R. O. Siwu, S. Hirosaki, T. Iwata, R. Matsumoto, Y. Kitagawa, A. R. Pradipta, M. Okumura, K. Fukase, Tetrahedron Lett., 53, 5899-5902 (2012).
Bio-Imaging and Cancer Targeting with Glycoproteins and N-Glycans, K. Fukase, K. Tanaka, Curr. Opin. Chem. Biol., 16, 614-621 (2012).
Development of Azaelectrocyclization-Based Labeling and Application to Noninvasive Imaging and Targeting Using N-Glycan Derivatives -In pursuit of N-Glycan Functions on Proteins, Dendrimers, and Living Cells, K. Tanaka, Trends in Glycoscience and Glycotechnology, 24, 47-64 (2012).
Template-Assisted and Self-Activating Clicked Peptide as a Synthetic Mimic of the SH2 Domain, K. Tanaka, S. Shirotsuki, C. Kageyama, T. Tahara, S. Nozaki, E. R. O. Siwu, T. Iwata, S. Tamura, S. Douke, N. Murakami, H. Onoe, Y. Watanabe, K. Fukase, ACS Chem. Biol., 7, 637-645 (2012).
Cell Surface Biotinylation by Azaelectrocyclization: Easy-Handling and Versatile Approach for Living Cell Labeling, K. Tanaka, S. Yokoi, K. Morimoto, T. Iwata, Y. Nakamoto, K. Nakayama, K. Koyama, T. Fujiwara, K. Fukase, Bioorg. Med. Chem., 20, 1865–1868 (2012).
Auxiliary-Directed Oxidation of Ursolic Acid by “Ru”-Porphyrins: Chemical Modulation of Cytotoxicity against Tumor Cell Lines, K. Tanaka, K. Mazumder, E. R. O. Siwu, S. Nozaki, Y. Watanabe, K. Fukase, Tetrahedron Lett., 53, 1756–1759 (2012).
Discovery and application of 6π-Azaelectrocyclization to natural product synthesis & synthetic biology, K. Tanaka, S. Katsumura, K. Fukase, Sci. China Chem., 55, 19-30 (2012).
Stereocontrolled Synthesis of Substituted Chiral Piperidines via One-Pot Asymmetric 6π-Azaelectrocyclization: Asymmetric Syntheses of (−)-Dendroprimine, (+)-7-Epidendroprimine, (+)-5-Epidendroprimine, and (+)-5,7-Epidendroprimine, T. Kobayashi, F. Hasegawa, Y. Hirose, K. Tanaka, H. Mori, S. Katsumura, J. Org. Chem., 77, 1812–1832 (2012).
鋳型誘起反応の開発に基づくリン酸化タンパク質認識ペプチドの化学転写合成, 田中克典, Peptide Newsletter Japan, The Japanese Peptide Society出版, 86, 15-19, (2012).
糖鎖の生体内イメージング, 田中克典, 深瀬浩一,ここまで進んだバイオセンシング・イメージング-１分子から細胞, 脳まで, CSJ Current Review 10, 株式会社化学同人出版, 114-122, (2012).
糖鎖機能解明に向けた新規化学修飾反応：糖鎖とリンパ球のin vivoイメージング, 深瀬浩一,田中克典, がん医療や創薬に貢献するin vivoイメージングと生体機能解析・制御の最前線 （実験医学増刊）, 疾患克服を目指したケミカルバイオロジー, 株式会社羊土社出版, 30, 第3章5項, (2012).
細菌由来複合糖質の合成と自然免疫研究, 深瀬浩一, 藤本ゆかり, 下山敦史, 田中克典, 有機合成化学協会誌, 70, 113-130 (2012).
Oligosaccharide Synthesis on Solid-supports, K. Tanaka, K. Fukase, In Solid-Phase Organic Synthesis Book, P. Toy (ed), Wiley, 489-530 (2012).
Effects on Glycan Heterogeneity on Microarray and Dendrimer, K. Tanaka, Trends in Glycoscience and Glycotechnology, 131, 155-157 (2011).
Exploring A Unique Reactivity of 6π-Azaelectrocyclization to Enzyme Inhibition, Natural Products Synthesis, and Molecular Imaging: An Approach to Chemical Biology by Synthetic Chemists, K.Tanaka, K. Fukase, S. Katsumura, Synlett, 2115-2139 (2011).
Reinvestigation of the C5-Acetamide Sialic Acid Donor for α-Selective Sialylation: Practical Procedure under Microfluidic Conditions, Y. Uchinashi, M. Nagasaki, J. Zhou, K. Tanaka, K. Fukase, Org. Biomol. Chem., 9, 7243-7248 (2011).
Ursolic Acid Derivatives from Bangladeshi Medicinal Plant, Sarauja roxburghii: Isolation and Cytotoxic Activity against A431 and C6 glioma Cell Lines, K. Mazumder, E. R. O. Siwu, K. Tanaka, S. Nozaki, Y. Watanabe, K. Fukase, Phytochem. Lett., 4, 287-291, (2011).
Target-Selective and Fluorescence “Switch-On” Protein Labeling by 6π-Azaelectrocyclization, K. Tanaka, M. Kitadani, K. Fukase, Org. Biomol. Chem., 9, 5346-5349 (2011).
天然物によるタンパク質不活性化機構に学ぶ6π-アザ電子環状反応の新奇反応性と天然物合成および合成生物学への展開, 田中克典, 有機合成化学協会誌, 69, 1389-1401 (2011).
マイクロフローシステムを用いた生理活性天然物の実用的合成戦略, 田中克典, 深瀬浩一, 月刊『未来材料』「解説Review」, 株式会社エヌ・ティー・エス出版, 11, 11-19 (2011).
マイクロ経路内および固相上での効率的グリコシル化反応を基盤としたN-結合型糖タンパク質糖鎖のライブラリー指向型合成, 田中克典, 深瀬浩一, 月刊ファインケミカル「糖鎖合成の進展と最新応用研究」, 株式会社シーエムシー出版, 40, 23-30 (2011).
効率的結合形成反応を起点とする『合成化学生物学』の提起：高速 6π-アザ電子環状反応の設計による生体高分子の非侵襲撃的イメージング, 田中克典, 大阪大学低温センターだより, 156, 16-23 (2011).
ペプチド・タンパク質、細胞の革新的標識法とPETによる動態解析への応用, 田中克典, 深瀬浩一, 次世代バイオ医薬品の製剤設計と開発戦略, 株式会社シーエムシー出版, 119-126 (2011).
新規標識反応を基盤とする糖鎖プローブの開発とインビボイメージング, 深瀬浩一, 田中克典, 蛍光イメーシング・MRIプローブの開発と最新動向, 株式会社シーエムシー出版, 35-43 (2011).
Asymmetric Synthesis of 14C-Labeled L-Propargylglycine, M. Kurosawa, K. Tanaka, K. Fukase, Radioisotopes, 59, 17-22 (2010).
Noninvasive Imaging of Dendrimer-type N-Glycan Clusters: In Vivo Dinamics Dependence on Oligosaccharides Structure, K. Tanaka, E. R. O. Siwu, K. Minami, K. Hasegawa, S. Nozaki, Y. Kanayama, K. Koyama, C. W. Chen, J. C. Paulson, Y. Watanabe, K. Fukase, Angew. Chem. Int. Ed., 49, 8195-8200 (2010).
A Combined 6π-Azaelectrocyclization/Staudinger Approach to Protein & Cell Engineering: Non-Invasive Tumor Targeting by N-Glycan-Engineered Lymphocytes, K. Tanaka, K. Minami, T. Tahara, E. R. O. Siwu, K. Koyama, S. Nozaki, H. Onoe, Y. Watanabe, K. Fukase, J. Carbohydr. Chem., 29, 118-132 (2010).
Electrocyclization-Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking, K. Tanaka, K. Minami, T. Tahara, Y. Fujii, E. R. O. Siwu, S. Nozaki, H. Onoe, S. Yokoi, K. Koyama, Y. Watanabe, K. Fukase, ChemMedChem, 5, 841-845 (2010).
In Vivo Imaging of Chemically Engineered Proteins and Cells by Oligosaccharides, K. Tanaka, Trends in Glycosci. Glycotechnol., 22, 48-50 (2010).
Probe Design & Synthesis of Galβ(1-3)[NeuAcα(2-6)]GlcNAcβ(1-2)Man Motif of N-Glycan, G.-M. Bao, K. Tanaka, K. Ikenaka, K. Fukase, Bioorg. Med. Chem., 18, 3760-3766 (2010).
A New Strategy in Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclization, K. Tanaka, K. Fukase, S. Katsumura, Chem. Rec., 10, 119-139 (2010).
糖鎖の非侵襲的インビボイメージング, 田中克典, 深瀬浩一, トランスレーショナルリサーチを支援する遺伝医学MOOK, 株式会社メディカルドゥ出版, 18, 66-73 (2010).
高反応性アミノ基標識プローブの設計に基づく生体高分子の非侵襲撃的イメージング, 田中克典, 深瀬浩一, 化学フロンティア2010: 生命現象を理解する分子ツール最前線-イメージングから生体機能解析まで-化学, 株式会社化学同人出版, 22, 54-62 (2010).
糖鎖関連物質の非侵襲的インビボイメージングによる診断法開発への展望, 田中克典, 深瀬浩一, 『生体の科学』, 株式会社医学書院、財団法人金原一郎記念医学医療振興財団出版, 61, 173-180 (2010).
マイクロフロー反応を鍵とする生理活性天然物の実用的合成戦略, 田中克典, 有機合成化学協会誌, 68, 124-135 (2010).
Self and Non-self Recognition with Bacterial and Animal Glycans, Surveys by Synthetic Chemistry, Y. Fujimoto, K. Tanaka, A. Shimoyama, K. Fukase, In Method in Enzymology, M. Fukuda (ed), Wiley, 478, 323-342 (2010).
Combinatorial Methods in Oligosaccharide Synthesis, K. Tanaka, Y. Fujimoto, S. Tanaka, Y. Mori, K. Fukase, In Glycoscience, B. Fraser-Reid, K. Tatsuta, J. Thiem (eds), Springer, (2010).
Polymer-supported and Tag-assisted Methods in Oligosaccharide Synthesis, K. Tanaka, K. Fukase, In Glycoscience, B. Fraser-Reid, K. Tatsuta, J. Thiem (eds), Springer, (2010).
Library-directed Solution- and Solid-phase Synthesis of 2,4-Disubstituted Pyridines: One-pot Approach via 6π -Azaelectrocyclization, T. Sakaguchi, T. Kobayashi, S. Hatano, H. Tsuchikawa, K. Fukase, K. Tanaka, S. Katsumura, Chem. Asian J., 4, 1573-1577 (2009).
Acid-Mediated Reactions under Microfluidic Conditions: A New Strategy for Practical Synthesis of Biofunctional Natural Products, K. Tanaka, K. Fukase, Beilstein Journal of Organic Chemistry, 5, No. 40 (2009).
Renaissance of Traditional Organic Reactions under Microfluidic Conditions: A New Paradigm for Natural Products Synthesis, K. Tanaka, K. Fukase, Org. Process Res. Dev., 13, 983-990 (2009).
Chemical N-Glycosylation by Asparagine under Combined Microfluidic/Batch Conditions, K. Tanaka, T. Miyagawa, K. Fukase, Synlett, 1571-1574 (2009).
Library-directed Synthesis of N-Glycans: Synthesis of Sialic Acid-containing Complex-type N-Glycan on Solid-supports, K. Tanaka, Y. Fujii, H. Tokimoto, Y. Mori, S. Tanaka, G.-M. Bao, E. R. O. Siwu, A. Nakayabu, K. Fukase, Chem. Asian J. 4, 574-580 (2009).
A Practical Synthesis of Manβ(1-4)GlcNTroc Fragment via Microfluidic β-Mannosylation, K. Tanaka, Y. Mori, K. Fukase, J. Carbohydr. Chem., 28, 1-11 (2009).
Chemistry-based Labeling and Engineering on Proteins and Cell Surfaces: Application to Non-invasive Imaging of Oligosaccharide Derivatives, K. Tanaka, K. Minami, E. R. O. Siwu, K. Fukase, Chemical Biology, Japanese Society for Chemical Biology, 2, 7-12 (2009).
細胞の糖鎖エンジニアリング, 田中克典, 深瀬浩一, 第三の生命鎖「糖鎖」を活用•制御するケミカルバイオロジー, 月刊BIO INDUSTRY, 株式会社シーエムシー出版, 27, 29-36 (2009).
糖鎖のインビボバイオイメージング, 田中克典, 深瀬浩一, 複合糖質の化学と最新応用技術, 正田晋一郎, 稲津敏行監修, 株式会社シーエムシー出版, 235-244 (2009).
Site-selective and Non-destructive Protein Labeling via Azaelectrocyclization-Induced Cascade Reactions, K. Tanaka, Y. Fujii, K. Fukase, ChemBioChem, 9, 2392-2395 (2008).
Recent Advances in Positron Emission Tomography (PET) Imaging of Biomolecules: From Chemical Labeling to Cancer Diagnostics, K. Tanaka, K. Fukase, Mini-Rev. Org. Chem., 5, 153-162 (2008).
Efficient Aldol Condensation in Aqueous Biphasic System under Microfluidic Conditions, K. Tanaka, S. Motomatsu, K. Koyama, K. Fukase, Tetrahedron Lett., 49, 2010-2012 (2008).
PET (Positron Emission Tomography) Imaging of Biomolecules Using Metal/DOTA Complexes: A New Collaborative Challenge by Chemists, Biologists, and Physicians for Future Diagnostics and Exploration of In vivo Dynamics, K. Tanaka, K. Fukase, Org. Biomol. Chem., 6, 815-828 (2008).
A Submicrogram-scale Protocol for Biomolecule-based PET Imaging via Rapid 6π -Azaelectrocyclization: First Visualization of Sialic Acid-dependent Circulatory Residence of Glycoproteins, K. Tanaka, T. Masuyama, K. Hasegawa, T. Tahara, H. Mizuma, Y. Wada, Y. Watanabe, K. Fukase, Angew. Chem. Int. Ed., 47, 102-105 (2008).
Efficient Synthesis of Oligosaccharides and Synthesis of Pathogen-Associated Molecular Patterns for Their Biofunctional Studies, K. Fukase, Y. Fujimoto, K. Tanaka, In Experimental Glycoscience, Glycochemistry, N. Taniguchi, A. Suzuki, Y. Ito, H. Narimatsu, T. Kawasaki, S. Hase (eds), Springer, 200-205 (2008).
Acceleration of Cu()-Mediated Huisgen 1,3-Dipolar Cycloaddition by Histidine Derivatives: Library Synthesis of “Self-Activating” Click Peptides, K. Tanaka, C. Kageyama, S. Shirotsuki, K. Fukase, Peptide Science, 171-174 (2007).
New Labeling Method of Biomolecules via Rapid Azaelectrocyclization: Application to PET Imaging, K. Tanaka, T. Masuyama, K. Minami, Y. Fujii, K. Hasegawa, T. Tahara, H. Mizuma, Y. Wada, Y. Watanabe, K. Fukase, Peptide Science, 91-94 (2007).
Acceleration of Cu(I)-mediated Huisgen 1,3-Dipolar Cycloaddition by Histidine Derivatives, K. Tanaka, C. Kageyama, K. Fukase, Tetrahedron Lett., 48, 6475-6479 (2007).
Highly Efficient α-Sialylation by Virtue of Fixed Dipole Effects of N-Phthalyl Group: Application to Continuous Flow Synthesis of α(2-3)- and α(2-6)-Neu5Ac-Gal Motifs by Microreactor, S. Tanaka, T. Goi, K. Tanaka, K. Fukase, J. Carbohydr. Chem., 26, 369-394 (2007).
Synthesis and Solid-State NMR of CD3-labeled 11-cis-Retinals, K. Tanaka, A. V. Struts, S. Krane, N. Fujioka, G. F. J. Salgado, K. Martínez-Mayorga, M. F. Brown, K. Nakanishi, Bull. Chem. Soc. Jpn., 80, 2177-2184 (2007).
Structural Analysis and Dynamics of Retinal Chromophore in Dark and Meta I States of Rhodopsin from 2H NMR of Aligned Membranes, A. V. Struts, G. F. J. Salgado, K. Tanaka, S. Krane, K. Nakanishi, M. F. Brown, J. Mol. Biol., 372, 50-66 (2007).
Synthesis and Assignment of the Absolute Configuration of Some Pyrrolo[2,3-b]Indoline Alkaloids through a Theoretical Simulation of Electronic Circular Dichroism/Optical Rotation Data, E. Gioegio, K. Tanaka, L. Verotta, K. Nakanishi, N. Berova, C. Rosini, Chirality, 19, 434-445 (2007).
Large-Scale Synthesis of Immunoactivating Natural Product, Pristane, by Continuous Microfluidic Dehydration as Key Step, K. Tanaka, S. Motomatsu, K. Koyama, S. Tanaka, K. Fukase, Org. Lett., 9, 299-302 (2007).
Efficient Procedure for Reductive Opening of Sugar 4,6-O-Benzylidene Acetals by a Microfluidic System, K. Tanaka, K. Fukase, Synlett, 164-166(2007).
Lithium Tetrakis(pentafluorophenyl)borate, K. Tanaka, K. Fukase, In Electronic Encyclopedia of Reagents for Organic Synthesis, (2007).
Synthesis of 2,4,6-Trisubstituted Chiral Piperidines and (-)-Dendroprimine by One-Pot Asymmetric Azaelectrocyclization Protocol, T. Kobayashi, F. Hasegawa, K. Tanaka, S. Katsumura, Org. Lett., 8, 3813-3816 (2006).
Development of a One-Pot Asymmetric Azaelectrocyclization Protocol: Synthesis of Chiral 2,4-Disubstituted 1,2,5,6-Tetrhydropiperidines, T. Kobayashi, M. Nakashima, T. Hakogi, K. Tanaka, S. Katsumura, Org. Lett., 8, 3809-3812 (2006).
Solid-State 2H NMR Structure of Retinal in Metarhodopsin I, G. F. J. Salgado, A. V. Struts, K. Tanaka, S. Krane, K. Nakanishi, M. F. J. Brown, J. Am. Chem. Soc., 128, 11067-11071 (2006).
マイクロスケールCross Metathesis/CD•FDCDプロトコルによる新規天然物絶対立体配置決定法, 田中克典, 有機合成化学協会誌, 64, 382-394 (2006).
Highly Efficient Sialylation towards α(2-3) and α(2-6)-Neu5Ac-Gal Synthesis: Significant “Fixed Dipole Effect” of N-Phthalyl Group on α-Selectivity, K. Tanaka, T. Goi, K. Fukase, Synlett, 2958-2962 (2005).
Highly β-Selective Mannosylation Towards Manβ1-4GlcNAc Synthesis: TMSB(C6F5)4 as a Lewis acid/Cation-Trap Catalyst, S. Tanaka, M. Takashina, H. Tokimoto, Y. Fujimoto, K. Tanaka, K. Fukase, Synlett, 2325-2328 (2005).
Oligosaccharide Synthesis by Using Affinity Separation Based on Molecular Recognition between Podand Ether and Ammonium Ion, K. Fukase, M. Takashina, Y. Hori, D. Tanaka, K. Tanaka, S. Kusumoto, Synlett, 2342-2346 (2005).
Determination of the Absolute Configuration of Flexible Molecules by ab initio ORD Calculations: A Case Study with Cytoxazones and Isocytoxazones, E. Giorgio, M. Roje, K. Tanaka, Z. Hamersak, V. Sunjic, K. Nakanishi, C. Risini, N. Berova, J. Org. Chem., 70, 6557-6563 (2005).
Theoretical Simulation of the Electronic Circular Dichroism Spectrum of Calicheamicin, E. Giorgio, K. Tanaka, W. Ding, G. Krishnamurthy, K. Pitts, G. A. Ellestad, C. Rosini, N. Berova, Bioorg. Med. Chem., 13, 5072-5079 (2005).
Unique Reactivity of α-Alkoxy Ginkgolide Lactones to Nucleophilic Reagents: Preparation of New Lactol Derivatives, K. Tanaka, M. Pimentel, N. Berova, K. Nakanishi, Bull. Chem. Soc. Jpn., 78, 1843-1850 (2005).
Three Challenges towards the Assignment of Absolute Configuration of Gymnocin-B, K. Tanaka, Y. Itagaki, M. Satake, H. Naoki, T. Yasumoto, K. Nakanishi, N. Berova, J. Am. Chem. Soc., 127, 9561-9570 (2005).
Preparation of Ginkgolide and F-Seco-ginkgolide Lactols: The Unique Reactivity of α-Hydroxy Lactones towards NaBH4, K. Tanaka, D. K. Kester, K. Nakanishi, N. Berova, Tetrahedron Lett., 46, 531-534 (2005).
Fluorescence Detected Exciton Coupled Circular Dichroism: Development of New Fluorescent Reporter Groups for Structural Studies, K. Tanaka, G. Pescitelli, K. Nakanishi, N. Berova, Monatsh. Chem., 136, 367-395 (2005).
Development of a Universal Ellipsoidal Mirror Device for Fluorescence Detected Circular Dichroism (FDCD) - Elimination of Polarization Artifacts, T. Nehira, K. Tanaka, T. Takakuwa, C. Ohshima, H. Masago, G. Pescitelli, A. Wada, N. Berova, Appl. Spectrosc., 59, 121-125 (2005).
酵素阻害機構に学ぶ速やかな6π-アザ電子環状反応とその展開, 田中克典, 化学と工業, 58, 113-116 (2005).
酵素阻害機構に学ぶ速やかな6π-アザ電子環状反応とその展開, 田中克典, 勝村成雄, 有機合成化学協会誌, 63, 696-708 (2005).
Deuterium NMR Structure of Retinal in the Ground State of Rhodopsin, G. F. J. Salgado, A. V. Struts, K. Tanaka, N. Fujioka, K. Nakanishi, M. F. Brown, Biochemistry, 43, 12819-12828 (2004).
Development of Highly Stereoselective Asymmetric 6π-Azaelectrocyclization of Conformationally Flexible Linear 1-Azatrienes. From Finding of Multi-Functional Chiral Amines, 7-Alkyl cis-1-Amino-2-indanols To Application as a New Synthetic Strategy; Formal Synthesis of 20-Epiuleine, K. Tanaka, T. Kobayashi, H. Mori, S. Katsumura, J. Org. Chem., 69, 5906-5925 (2004).
Metalloporphyrin Sensors for Supramolecular Chiral Recognition: Chiroptical Study, N. Berova, M. Balaz, M. Giraud, A. Holmes, H. Ishii, H. Matsuda, K. Nakanishi, G. Pescitelli, G. Proni, K. Tanaka, J. Porphyrins Phthalocyanines, 8, 347 (2004).
Synthesis of New Chiral Auxiliaries for 6π-Azaelectrocyclization: 4- and 7-Alkyl Substituted cis-1-Amino-2-indanols, T. Kobayashi, K. Tanaka, J. Miwa, S. Katsumura, Tetrahedron Asymmetry, 15, 185-188 (2004).
Absolute Stereochemistry of Dihydroangelicines Bearing C-8 Substituted Double Bonds: A Combined Chemical/exciton Chirality Protocol, K. Tanaka, G. Pescitelli, L. Di Bari, T. L. Xiao, K. Nakanishi, D. W. Armstrong, N. Berova, Org. Biomol. Chem., 2, 48-58 (2004).
Absolute Stereochemistry of Allylic Alcohols, Amines and Other Ene Moieties: A Microscale Cross Metathesis / Exciton Chirality Protocol, K. Tanaka, K. Nakanishi, N. Berova, J. Am. Chem. Soc., 125, 10802-10803 (2003).
Development of New Wittig Reagent, Silylfuranmethylid, and its Reactivity, K. Tanaka, T. Hata, H. Hara, S. Katsumura, Tetrahedron, 59, 4945-4952 (2003).
酵素阻害機構に学ぶ速やかな6π-アザ電子環状反応 -その出会いと開発に向けて, 化学, 58, 46-47 (2003).
Highly Stereoselective Asymmetric 6π-Azaelectrocyclization Utilizing the Novel 7-Alkyl Substituted cis-1-Amino-2-indanols: Formal Synthesis of 20-Epiuleine, K. Tanaka, S. Katsumura, J. Am. Chem. Soc., 124, 9660-9661 (2002).
Significant Acceleration of 6π-Azaelectrocyclization Resulting from a Remarkable Substituent Effect, and Formal Synthesis of the Ocular Age Pigment A2-E by a New Method for Substituted Pyridine Synthesis, K. Tanaka, H. Mori, M. Yamamoto, S. Katsumura, J. Org. Chem., 66, 3099-3110 (2001).
Novel Synthesis of the Ocular Age Pigment A2-E: New Method for Substituted Pyridine Synthesis via Azaelectrocyclization, K. Tanaka, S. Katsumura, Org. Lett., 2, 373-375 (2000).
First Synthesis of (-)-Spongianolide A and Determination of its Absolute Structure, T. Hata, K. Tanaka, S. Katsumura, Tetrahedron Lett., 40, 1731-1734 (1999).
The Inhibitory Mechanism of Bovine Pancreatic Phospholipase A2 by Aldehyde Terpenoids, K. Tanaka, M. Kamatani, H. Mori, S. Fujii, K. Ikeda, M. Hisada, Y. Itagaki, S. Katsumura, Tetrahedron, 55, 1657-1686 (1999).
アルデヒドテルペノイドによるホスホリパーゼA2不活性化機構, 田中克典, 勝村成雄, 有機合成化学協会誌, 57, 876-887 (1999).
Synthesis of a New Phospholipase A2 Inhibitor of an Aldehyde Terpenoid and its Possible Inhibitory Mechanism, K. Tanaka, M. Kamatani, H. Mori, S. Fujii, K. Ikeda, M. Hisada, Y. Itagaki, S. Katsumura, Tetrahedron Lett., 39, 1185-1188 (1998).

References: V. 
 V. 
 V. 
 V. 
 V. 
 V.