Source: http://www.msdecisions.ru/conferences/
Timestamp: 2019-04-19 18:19:58+00:00

Document:
Conference presentations of our research team members.
Veronika Voronova, Victor Sokolov, Dina Chenikova, Amani Al-Khaifi, Sara Straniero, Chanchal Kumar, Kirill Peskov, Gabriel Helmlinger, Mats Rudling, Bo Angelin. A physiology-based model of the distribution of individual bile acids within the enterohepatic circulation under normal and pathological conditions in human. XXV International Bile Acid Meeting: Bile Acids in Health and Disease 2018, Dublin, Ireland.
Victor Sokolov, Tatiana Yakovleva, Shinya Ueda, Joanna Parkinson, Robert C. Penland, David W. Boulton, Weifeng Tang. Dapagliflozin Exposure–Response in Japanese vs Non-Japanese Patients with Type 1 Diabetes. 78th Scientific Sessions of American Diabetes Association, Orlando, USA.
V Voronova, K Zhudenkov, R C. Penland, D W. Boulton, G Helmlinger, K Peskov. Exenatide effects on gastric emptying and oral glucose appearance in plasma: A quantitative assessment using an integrative systems pharmacology model. 9th American Conference on Pharmacometrics (ACoP9), San-Diego, USA.
Victor Sokolov, Artem Dolgun, Kirill Zhudenkov, Henning Schmidt, Gabriel Helmlinger, Kirill Peskov. Evaluation of the utility of a MATLAB and R-based workflow for the development of quantitative systems pharmacology (QSP) models. 9th American Conference on Pharmacometrics (ACoP9), San-Diego, USA.
Yuri Kosinsky, Ivan Azarov, Lulu Chu, Gabriel Helmlinger, Kirill Peskov, Sergey Aksenov. Comparison of different approaches to modeling early tumor size dynamics for accurate prediction of survival in non-small cell lung cancer (NSCLC) clinical trials. 9th American Conference on Pharmacometrics (ACoP9), San-Diego, USA.
Kirill Zhudenkov, Dina Chernikova, Oleg Stepanov, Sergey Aksenov, Nidal Al-Huniti, Kirill Peskov, Oleg Stepanov, Gabriel Helmlinger, Kirill Peskov. UA use of multiple individual lesion measuress diameters vs. Sum- of- target- lLesions- Diameters (SLD) for prediction of patient survival in non-small cell lung cancer (NSCLC). 9th American Conference on Pharmacometrics (ACoP9), San-Diego, USA.
Veronika Voronova, Lulu Chu, Yuri Kosinsky, Alexandra Borodovsky, Richard Woessner, Kris Sachsenmeier, Ganesh Mugundu, Melinda Merchant, Wenlin Shao, Kirill Peskov, Gabriel Helmlinger. Anti-tumor synergy evaluation of an AZD4635/ anti-PD-L1 combination therapy using a quantitative systems model. The Society for Immunotherapy of Cancer Annual Meeting, Washington D.C., USA.
Yuri Kosinsky, Simon Dovedi, Kirill Peskov, Veronika Voronova, Lulu Chu, Don Stanski, Gabriel Helmlinger. Immune cell responses and dose scheduling optimization of radiation and anti-PD-L1 treatment combination using a joint experimental and systems modeling approach. The Society for Immunotherapy of Cancer Annual Meeting, Washington D.C., USA.
Boris Shulgin, Yuri Kosinsky, Andrey Omelchenko, Lulu Chu, Ganesh Mugundu, Garrett DeYulia, Rodrigo Pimentel, Kirill Peskov, Gabriel Helmlinger. Characterizing immune-mediated adverse events of anti-PD-1 and anti-CTLA-4 monotherapies and combinations using a quantitative model based meta-analysis. The Society for Immunotherapy of Cancer Annual Meeting, Washington D.C., USA.
Victor Sokolov, Eva Hurt-Camejo, Catarina Nilsson, Kirill Zhudenkov, Stanko Skrtic, Bengt Hamrén, Kirill Peskov, Gabriel Helmlinger, Rasmus Jansson-Löfmark (2018) Differentiation of anti-PCSK9 antibodies and synthesis inhibitors: a drug-disease modeling study. ASCPT 2018 Annual Meeting, Orlando, FL, USA.
Tatiana Yakovleva, Victor Sokolov, Lulu Chu, Robert C. Penland, Weifeng Tang, Peter J. Greasley, Susanne Johansson, Kirill Peskov, Gabriel Helmlinger, David W. Boulton (2018) Contribution and regulation of SGLT1 and SGLT2 in healthy and type 2 diabetes subjects: a drug-disease modeling study. ASCPT 2018 Annual Meeting, Orlando, FL, USA.
Artem Dolgun, Victor Sokolov, Henning Schmidt, Nidal Al-Huniti, Gabriel Helmlinger, Kirill Peskov (2018) A functional, integrative R environment workflow for the development and use of quantitative systems pharmacology models. PAGE 2018 Conference, Montreux, Switzerland.
Veronika Voronova, Victor Sokolov, Dina Chenikova, Amani Al-Khaifi, Sara Straniero, Chanchal Kumar, Kirill Peskov, Gabriel Helmlinger, Mats Rudling, Bo Angelin (2018) Using a physiologically-based QSP model to simulate the effects of enterohepatic circulation perturbations on the distribution of bile acids. PAGE 2018 Conference, Montreux, Switzerland.
Kosinsky Yu, Chu L, Peskov K, Voronova V, Borodovsky A, Woessner R, Sachsenmeier K, Al-Huniti N, Helmlinger G. (2018) Quantitative modeling as a systematic approach for drug combination evaluation in Immuno-Oncology. AACR 2018 annual meeting, Chicago, USA.
Kosinsky, Y., Dovedi, S., Peskov, K., Voronova, V., Chu, L., Tomkinson, H., Al-Huniti, N., Stanski, D., & Helmlinger, G. (2017) Radiation and anti-PD-L1 treatment combinations: Immune cell responses and dose scheduling optimization using a joint experimental and systems modeling approach. PKUK 2017 Meeting, Great Malvern, UK.
Sokolov, V., Chu, L., Kosinski, Y., Al-Huniti, N., Fox, R., Schmidt, H., Onishchenko, D., Voronova, , Zhudenkov, K., Helmlinger, G., & Peskov, K. (2017) Drug-Disease modeling: a practical workflow from model development to simulations. 8th American Conference on Pharmacometrics (ACoP8), Fort Lauderdale, USA.
Al-Huniti, N., Onishchenko, D., Xu, H., Zhou, D., Masson, E., Helmlinger, G., Tomkinson, H., Abdallah, & K., Dunyak, J. (2017) Dynamic prediction of pregression free survival (PFS) and overall survival (OS) in non-small cell lung cancer (NSCLC) using tumor size: A longitudinal joint modeling approach. ASCPT meeting, Washington D.C., USA.
Sokolov, V., Hurt-Camejo, E., Nilsson, C., Zhudenkov, K., Skrtic, S., Hamren, B., Peskov, K., Helmlinger, G., & Jansson-Lofmark, R. (2017) Properties of Anti-PCSK9 Antibodies and Synthesis Inhibitors Using a Quantitative Systems Model of Lipoprotein Metabolism. American Diabetic Association (ADA) scientific sessions, San Diego, California.
Azarov, I., Peskov, K., Kosinsky, Y., & Helmlinger, G. (2017) Agent-based modelling of T cell movement in a lymph node: does chemo-attraction towards dendritic cells accelerate T cell repertoire scanning? 17th Biomat Symposium on Mathematical and Computational Biologym, Moscow, Russia.
Sokolov, V., Onishchenko, D., Zhudenkov, K., Helmlinger, G., & Peskov, K. (2017) Estimation of uncertainty and variability for systems pharmacology models using models using Monte-Carlo simulations. 17th Biomat Symposium on Mathematical and Computational Biologym, Moscow, Russia.
Voronova, V. M., Zhudenkov, K. V., & Peskov, K. V. (2017) Creation and application of mathematical models of carbohydrate metabolism for the development and optimization of diabetes therapy. Mathematics, Computer, Education. Pushchino, Russia.
Voronova, V., Sokolov, V., Al-Khaifi, A., Straniero, S., Rudling, M., Chanchal, K., Peskov, K., Helmlinger, G., & Angelin, B. (2017) Systems Pharmacology Modeling of Bile Acid Distribution and Signaling in Humans. Keystone symposia: Bile Acid Receptors as Signal Integrators in Liver and Metabolism, Monterey, USA.
Kosinsky, Y., Peskov, K., Shulgin, B., Stepanov, O., Voronova, V., Masson, E., & Helmlinger, G. (2016) Qunatitative Systems Pharmacology model for immuno-oncology drug development: example of CTLA4 inhibition mechanism. International Conference on Systems Biology (ICSB), Barcelona, Spain.
Peskov, K., Stepanov, O., Voronova, V., Kosinsky, Y., Masson, E., & Helmlinger, G. (2016) A quantitative systems pharmacology model to explore combination efficacy of immuno-oncology compounds: Effects of CXCR2 and PD-1 inhibitions. International Conference on Systems Biology (ICSB), Barcelona, Spain.
Shulgin, B., Helmlinger, G., & Kosinsky, Y. (2016) Enchancement of cytokine signaling via cytokine-neutralizing antibodies, International Conference on Systems Biology (ICSB), Barcelona, Spain.
Girnyk, A., Omelchenko, A., Vergun, A., & Ryskov A. (2016) Genetic and clonal variation in the D. armeniaca. Book of Abstracts of 9th Symposium on the Lacertids of the Mediterranean Basin & 1st Symposium, Lemesos (Limassol), Cyprus, 55.
Voronova, V., Karelina, T., Demin, O., & Chen, D. (2015) Understanding of GFR (Glomerular Filtration Rate) Changes in Response to ARB Administration using a Quantitative Systems Pharmacology Approach. ASCPT meeting, Indianapolis, USA.
Yakovleva, T., Demin, O. Jr., & Demin, O. (2015) Evaluation of minimum threshold hepatitis C virus concentration in plasma required for disease development. The 12th congress of EACPT.
Yakovleva, T., Demin, O. Jr., & Demin, O. (2015) The systems pharmacology model of hepatitis C progression and treatment. ASCPT meeting, Indianapolis, USA.
Yakovleva, T., Demin, O. Jr., & Demin, O. (2015) The systems pharmacology model of hepatitis C progression: evaluation of minimal viral concentration required for disease development. The 15th International Symposium on Viral Hepatitis and Liver Disease (ISVHLD).
Voronova, V.(2015) Mechanistic modeling approach for explanation of “metabolic memory” phenomena among diabetic patients. II Russian-Finnish Symposium “Emerging Trends in Drug Development”, Saint-Petersburg, Russia.
Caputo, A., &Peskov, K. (2014) Modeling Alzheimer’s Disease Progression Using the CDR Sum of Boxes Data from ADNI and in-house clinical data. Novartis Biostatistics conference, Basel, Switzerland.
Dua, P., Demin, O. Jr., Sokolov, V., Yakovleva, T., Demin, O., & Van der Graaf, P. (2014) A systems pharmacology model of purine metabolism to explore novel options for the treatment of Gout. Systems Pharmacology in Drug Discovery & Development, Noordwijkerhout, Netherlands.
Peskov, K. (2014) Integrated drug and disease modelling for dose selection, a step towards personalized medicine. The 4th international conference “Post-genome Methods of Analysis in Biology and Laboratory and Clinical Medicine”, Kazan, Russia.
Voronova, V., Demin, O. Jr., Smirnov, S., & Demin, O. (2014) Development and Application of Systems Pharmacology Model to Predict Nausea Resulted from Administration of GLP-1 Analogues. ASCPT meeting, Indianapolis, USA.
Yakovleva, T., Demin, O. Jr., & Demin, O. (2014) Investigation of Dapagliflozin inhibition effect on glucose reabsorption using systems pharmacology approach. ASCPT Annual Meeting.
Chen, D., Voronova, V., Smirnov, S., Goryacheva, E., Bakhmutova, A., & Demin, O. (2013) Development of Human System Pharmacology model to Characterize Diabetic Nephropathy Disease Progression and the Effect of Standard of Care Therapy. ACoP meeting, Fort Lauderdale, USA.
Kosinsky, Y., Peskov, K., Popenko, A., Tyakht, A., & Alexeev, D. (2013) Modeling of short-chain fatty acids metabolism in human gut: reconstruction of possible relations between microbiota composition and type 2 diabetes status. International Conference on Systems Biology (ICSB), Copenhagen, Denmark.
Kosinsky, Y., Peskov, K., Popenko, A., Tyakht, A., & Alexeev, D. (2013) Modeling of short-chain fatty acids metabolism in human gut. FEBS congress, St. Petersburg, Russia.
Karelina, T., Kazimirova, E., Zhudenkov, K., Demin, O. Jr, Lu, Y., Nicholas, T., Duvvuri, S., & Barton, H. A. (2012) Kinetic Model of Amyloid Beta Distribution and Allometric Scaling from Mouse to Monkey and Human. Population Approach Group Europe meeting (PAGE), Venice, Italy.
Petrosyan, V. G., Dergunova N. N., Bessonov S. A., & Omelchenko A. V. (2012) Мodeling the dynamics of populations size and comparative analysis of the demographic parameters (sexual and age structure) of moose in the Russia and Finland using long-term monitoring data. Book of abstract. 7th International Moose Symposium, Poland, 53.
Svetlichny, D., Peskov, K., Demidenko, A., Demin, O., Kraynov, E., & Spilker, M. (2011) Systems modeling of integrin avb3 signaling pathway. International Conference on Systems Biology (ICSB), Heidelberg/Mannheim, Germany.
Omelchenko, A. V., Vergun, A. A., Petrosyan, V. G., & Tokarskaya, O. N. (2011) Models of molecular genetic structures of populations of D. unisexualis on the basis of molecular marking of the genomes. Proceedings of the International conference “Biological diversity and conservation problems”, Yerevan, Armenia, 224 — 227.
Karelina, T., Demin, O., Zhudenkov, K., Svetlichny, D., Demin, O. Jr., Fairman, D., & Agoram, B. (2010) Can systems modeling approach be used to understand complex PK-PD relationships? A case study of 5-lipoxygenase inhibition by zileuton. Abstracts of the Annual Meeting of the Population Approach Group in Europe (PAGE).
Pedentchouk, N., Peskov, K., Borland, A., Cartlidge, L., & Wagner, T. (2010) What causes Differences in 13C/12C and D/H Composition of n-Alkanes from Leaf Waxes among Higher Terrestrial Plants? Stable Isotopes and Biogeochemical Cycles in Terrestrial Ecosystems Conference, Ascona, Switzerland.
Petrosyan, V. G., Khlyap, L. A., Bobrov, V. V., Warshavskiy, A. A., Bessonov, S. A., Dergunova, N. N., & Omelchenko, A. V. (2010) WEB-oriented information retrieval system and database «Alien species of mammals in ecosystems of Russia”. Book of Abstracts of the III International Symposium “Invasion of alien species in Holartic. Borok – 3”, Borok-Myshkin, Russia, 79.

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