Source: https://www.bordeaux-neurocampus.fr/staff/erwan-bezard/
Timestamp: 2019-04-22 13:26:00+00:00

Document:
Local transgene expression and whole-body transgenesis to model brain diseases in nonhuman primate.
Lucie Chansel-Debordeaux, Erwan Bezard. Anim Models Exp Med. 2019-01-29.
The hidden side of Parkinson’s disease: studying pain, anxiety and depression in animal models..
Fanny Faivre, Anil Joshi, Erwan Bezard, Michel Barrot. Neuroscience & Biobehavioral Reviews. 2019-01-01. 96 : 335-352.
Microdialysis in awake macaque monkeys for central nervous system pharmacokinetics.
Thibaud Thiollier, Caisheng Wu, Gregory Porras, Erwan Bezard, Qin Li, Jinlan Zhang, Hugues Contamin. Anim Models Exp Med. 2018-12-01. 1(4) : 314-321.
G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice..
Salvatore Novello, Ludovico Arcuri, Sandra Dovero, Nathalie Dutheil, Derya R. Shimshek, Erwan Bezard, Michele Morari. Neurobiology of Disease. 2018-12-01. 120 : 21-33.
Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts..
Alberto J. Espay, Francesca Morgante, Aristide Merola, Alfonso Fasano, Luca Marsili, Susan H. Fox, Erwan Bezard, Barbara Picconi, Paolo Calabresi, Anthony E. Lang. Ann Neurol.. 2018-11-30. 84(6) : 797-811.
Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases..
Geoffrey Prévot, Federico N. Soria, Marie-Laure Thiolat, Jonathan Daniel, Jean Baptiste Verlhac, Mireille Blanchard-Desce, Erwan Bezard, Philippe Barthélémy, Sylvie Crauste-Manciet, Benjamin Dehay. Bioconjugate Chem.. 2018-11-13. 29(12) : 4083-4089.
The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia..
Estefania Rojo-Bustamante, Miguel Angel Abellanas, Pedro Clavero, Marie-Laure Thiolat, Qin Li, Maria Rosario Luquin, Erwan Bezard, Maria S. Aymerich. Neurobiology of Disease. 2018-10-01. 118 : 64-75.
Meta-analysis of amantadine efficacy for improving preclinical research reliability..
Philip Stanley, Elsa Y. Pioli, Rouba Kozak, Michael Popiolek, Erwan Bezard. Mov Disord.. 2018-10-01. 33(10) : 1555-1557.
An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates..
Delphine Charvin, Therese Di Paolo, Erwan Bezard, Laurent Gregoire, Akihiro Takano, Guillaume Duvey, Elsa Pioli, Christer Halldin, Rossella Medori, François Conquet. Mov Disord.. 2018-09-14. 33(10) : 1619-1631.
Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics.
Marco Capogrosso, Fabien B. Wagner, Jerome Gandar, Eduardo Martin Moraud, Nikolaus Wenger, Tomislav Milekovic, Polina Shkorbatova, Natalia Pavlova, Pavel Musienko, Erwan Bezard, Jocelyne Bloch, Grégoire Courtine. Nat Protoc. 2018-09-01. 13(9) : 2031-2061.
Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing..
Barry Boland, Wai Haung Yu, Olga Corti, Bertrand Mollereau, Alexandre Henriques, Erwan Bezard, Greg M. Pastores, David C. Rubinsztein, Ralph A. Nixon, Michael R. Duchen, Giovanna R. Mallucci, Guido Kroemer, Beth Levine, Eeva-Liisa Eskelinen, Fanny Mochel, Michael Spedding, Caroline Louis, Olivier R. Martin, Mark J. Millan. Nat Rev Drug Discov. 2018-08-17. 17(9) : 660-688.
Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats..
Lucie Chansel-Debordeaux, Mathieu Bourdenx, Nathalie Dutheil, Sandra Dovero, Marie-Helene Canron, Clement Jimenez, Erwan Bezard, Benjamin Dehay. Human Gene Therapy Methods. 2018-08-01. 29(4) : 189-199.
Cardinal Motor Features of Parkinson’s Disease Coexist with Peak-Dose Choreic-Type Drug-Induced Dyskinesia..
Etienne Goubault, Hung P. Nguyen, Sarah Bogard, Pierre J. Blanchet, Erwan Bézard, Claude Vincent, Mélanie Langlois, Christian Duval. JPD. 2018-06-13. 8(2) : 323-331.
Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism..
Jérôme Baufreton, Tomislav Milekovic, Qin Li, Steve McGuire, Eduardo Martin Moraud, Grégory Porras, Shiqi Sun, Wai Kin D. Ko, Marine Chazalon, Stéphanie Morin, Elisabeth Normand, Géraldine Farjot, Aude Milet, Jan Pype, Elsa Pioli, Gregoire Courtine, Baptiste Bessière, Erwan Bezard. Mov Disord.. 2018-05-14.
The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline..
David Castonguay, Julien Dufort-Gervais, Caroline Ménard, Manavi Chatterjee, Rémi Quirion, Bruno Bontempi, Jay S. Schneider, Amy F.T. Arnsten, Angus C. Nairn, Christopher M. Norris, Guylaine Ferland, Erwan Bézard, Pierrette Gaudreau, Paul J. Lombroso, Jonathan Brouillette. Current Biology. 2018-04-01. 28(7) : 1079-1089.e4.
Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models..
Angelo Iannielli, Simone Bido, Lucrezia Folladori, Alice Segnali, Cinzia Cancellieri, Alessandra Maresca, Luca Massimino, Alicia Rubio, Giuseppe Morabito, Leonardo Caporali, Francesca Tagliavini, Olimpia Musumeci, Giuliana Gregato, Erwan Bezard, Valerio Carelli, Valeria Tiranti, Vania Broccoli. Cell Reports. 2018-02-01. 22(8) : 2066-2079.
Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias..
Jennifer Stanic, Manuela Mellone, Francesco Napolitano, Claudia Racca, Elisa Zianni, Daiana Minocci, Veronica Ghiglieri, Marie-Laure Thiolat, Qin Li, Annalisa Longhi, Arianna De Rosa, Barbara Picconi, Erwan Bezard, Paolo Calabresi, Monica Di Luca, Alessandro Usiello, Fabrizio Gardoni. Neurobiology of Disease. 2017-12-01. 108 : 54-64.
Experimental animal models of Parkinson’s disease: A transition from assessing symptomatology to α-synuclein targeted disease modification.
Wai Kin D. Ko, Erwan Bezard. Experimental Neurology. 2017-12-01. 298 : 172-179.
A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson’s disease..
Wai Kin D. Ko, Qin Li, Long Yun Cheng, Micaela Morelli, Manolo Carta, Erwan Bezard. European Journal of Pharmacology. 2017-10-01. 813 : 10-16.
Past, present, and future of Parkinson’s disease: A special essay on the 200th Anniversary of the Shaking Palsy..
J.A. Obeso, M. Stamelou, C.G. Goetz, W. Poewe, A.E. Lang, D. Weintraub, D. Burn, G.M. Halliday, E. Bezard, S. Przedborski, S. Lehericy, D.J. Brooks, J.C. Rothwell, M. Hallett, M.R. DeLong, C. Marras, C.M. Tanner, G.W. Ross, J.W. Langston, C. Klein, V. Bonifati, J. Jankovic, A.M. Lozano, G. Deuschl, H. Bergman, E. Tolosa, M. Rodriguez-Violante, S. Fahn, R.B. Postuma, D. Berg, K. Marek, D.G. Standaert, D.J. Surmeier, C.W. Olanow, J.H. Kordower, P. Calabresi, A.H.V. Schapira, A.J. Stoessl. Mov Disord.. 2017-09-01. 32(9) : 1264-1310.
Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease.
Decreased Rhes mRNA levels in the brain of patients with Parkinson’s disease and MPTP-treated macaques..
Francesco Napolitano, Emily Booth Warren, Sara Migliarini, Daniela Punzo, Francesco Errico, Qin Li, Marie-Laure Thiolat, Angelo Luigi Vescovi, Paolo Calabresi, Erwan Bezard, Micaela Morelli, Christine Konradi, Massimo Pasqualetti, Alessandro Usiello. PLoS ONE. 2017-07-25. 12(7) : e0181677.
Alterations in functional cortical hierarchy in hemiparkinsonian rats..
Borbála Nóra Jávor-Duray, Martin Vinck, Marcel van der Roest, Erwan Bezard, Henk W. Berendse, Thomas Boraud, Pieter Voorn. J. Neurosci.. 2017-07-07. 37(32) : 7669-7681.
In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains..
Fabio Cavaliere, Loic Cerf, Benjamin Dehay, Paula Ramos-Gonzalez, Francesca De Giorgi, Mathieu Bourdenx, Alban Bessede, Jose A. Obeso, Carlos Matute, François Ichas, Erwan Bezard. Neurobiology of Disease. 2017-07-01. 103 : 101-112.
U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells.
Mathieu Schmitt, Benjamin Dehay, Erwan Bezard, F. Javier Garcia-Ladona. Synapse. 2017-06-20. 71(9) : e21980.
Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration..
Federico N. Soria, Michel Engeln, Marta Martinez-Vicente, Christelle Glangetas, María José López-González, Sandra Dovero, Benjamin Dehay, Elisabeth Normand, Miquel Vila, Alexandre Favereaux, François Georges, Christophe Lo Bianco, Erwan Bezard, Pierre-Olivier Fernagut. Human Molecular Genetics. 2017-05-17. 26(14) : 2603-2615.
Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model..
Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate..
Anna Migdalska-Richards, Wai Kin D. Ko, Qin Li, Erwan Bezard, Anthony H. V. Schapira. Synapse. 2017-03-17. 71(7) : e21967.
Impulse control disorders and levodopa-induced dyskinesias in Parkinson’s disease: an update..
Valerie Voon, T Celeste Napier, Michael J Frank, Veronique Sgambato-Faure, Anthony A Grace, Maria Rodriguez-Oroz, Jose Obeso, Erwan Bezard, Pierre-Olivier Fernagut. The Lancet Neurology. 2017-03-01. 16(3) : 238-250.
Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity..
Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice..
Anna Migdalska-Richards, Liam Daly, Erwan Bezard, Anthony H. V. Schapira. Ann Neurol.. 2016-11-01. 80(5) : 766-775.
An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models.
Wai Kin D. Ko, Sandrine M. Camus, Qin Li, Jianzhong Yang, Steve McGuire, Elsa Y. Pioli, Erwan Bezard. Neuropharmacology. 2016-11-01. 110 : 48-58.
Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy..
Michel Engeln, Solène Ansquer, Emilie Dugast, Erwan Bezard, David Belin, Pierre-Olivier Fernagut. Neuropharmacology. 2016-10-01. 109 : 69-77.
LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain..
René Fuertig, Angelo Ceci, Sandrine M Camus, Erwan Bezard, Andreas H Luippold, Bastian Hengerer. Bioanalysis. 2016-09-01. 8(18) : 1903-1917.
Erwan Bezard. Ann Neurol.. 2016-06-24. 80(2) : 310-310.
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia..
Weixing Shen, Joshua L. Plotkin, Veronica Francardo, Wai Kin D. Ko, Zhong Xie, Qin Li, Tim Fieblinger, Jürgen Wess, Richard R. Neubig, Craig W. Lindsley, P. Jeffrey Conn, Paul Greengard, Erwan Bezard, M. Angela Cenci, D. James Surmeier. Neuron. 2016-06-01. 90(5) : 1139.
A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson’s Disease..
François Tison, Charlotte Keywood, Mark Wakefield, Franck Durif, Jean-Christophe Corvol, Karla Eggert, Mark Lew, Stuart Isaacson, Erwan Bezard, Sonia-Maria Poli, Christopher G. Goetz, Claudia Trenkwalder, Olivier Rascol. Mov Disord.. 2016-05-23. 31(9) : 1373-1380.
Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson’s disease..
Ludovico Arcuri, Riccardo Viaro, Simone Bido, Francesco Longo, Mariangela Calcagno, Pierre-Olivier Fernagut, Nurulain T. Zaveri, Girolamo Calò, Erwan Bezard, Michele Morari. Neurobiology of Disease. 2016-05-01. 89 : 55-64.
Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson disease..
Thibaud Thiollier, Caisheng Wu, Hugues Contamin, Qin Li, Jinlan Zhang, Erwan Bezard. Synapse. 2016-03-15. 70(6) : 231-239.
Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson’s disease..
Annalisa Pinna, Wai Kin D. Ko, Giulia Costa, Elisabetta Tronci, Camino Fidalgo, Nicola Simola, Qin Li, Mojgan Aghazadeh Tabrizi, Erwan Bezard, Manolo Carta, Micaela Morelli. Mov Disord.. 2016-02-12. 31(4) : 501-511.
Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury..
Nikolaus Wenger, Eduardo Martin Moraud, Jerome Gandar, Pavel Musienko, Marco Capogrosso, Laetitia Baud, Camille G Le Goff, Quentin Barraud, Natalia Pavlova, Nadia Dominici, Ivan R Minev, Leonie Asboth, Arthur Hirsch, Simone Duis, Julie Kreider, Andrea Mortera, Oliver Haverbeck, Silvio Kraus, Felix Schmitz, Jack DiGiovanna, Rubia van den Brand, Jocelyne Bloch, Peter Detemple, Stéphanie P Lacour, Erwan Bézard, Silvestro Micera, Grégoire Courtine. Nat Med. 2016-01-18. 22(2) : 138-145.
Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases..
Mathieu Bourdenx, Jonathan Daniel, Emilie Genin, Federico N. Soria, Mireille Blanchard-Desce, Erwan Bezard, Benjamin Dehay. Autophagy. 2016-01-13. 12(3) : 472-483.
Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line..
Mathieu Schmitt, Benjamin Dehay, Erwan Bezard, F. Javier Garcia-Ladona. Synapse. 2016-01-06. 70(3) : 71-86.
Striatal NELF-mediated RNA polymerase II stalling controls L-dopa induced dyskinesia..
Matthieu F. Bastide, Simone Bido, Nathalie Duteil, Erwan Bézard. Neurobiology of Disease. 2016-01-01. 85 : 93-98.
Weixing Shen, Joshua L. Plotkin, Veronica Francardo, Wai Kin D. Ko, Zhong Xie, Qin Li, Tim Fieblinger, Jürgen Wess, Richard R. Neubig, Craig W. Lindsley, P. Jeffrey Conn, Paul Greengard, Erwan Bezard, M. Angela Cenci, D. James Surmeier. Neuron. 2015-11-01. 88(4) : 762-773.
Why bother using non-human primate models of cognitive disorders in translational research?.
Sandrine Camus, Wai Kin D. Ko, Elsa Pioli, Erwan Bezard. Neurobiology of Learning and Memory. 2015-10-01. 124 : 123-129.
Alpha-synuclein propagation: New insights from animal models..
Benjamin Dehay, Miquel Vila, Erwan Bezard, Patrik Brundin, Jeffrey H. Kordower. Mov Disord.. 2015-09-08. 31(2) : 161-168.
Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates..
Lucia Friedli, Ephron S. Rosenzweig, Quentin Barraud, Martin Schubert, Nadia Dominici, Lea Awai, Jessica L. Nielson, Pavel Musienko, Yvette Nout-Lomas, Hui Zhong, Sharon Zdunowski, Roland R. Roy, Sarah C. Strand, Rubia van den Brand, Leif A. Havton, Michael S. Beattie, Jacqueline C. Bresnahan, Erwan Bézard, Jocelyne Bloch, V. Reggie Edgerton, Adam R. Ferguson, Armin Curt, Mark H. Tuszynski, Grégoire Courtine. Sci. Transl. Med.. 2015-08-26. 7(302) : 302ra134-302ra134.
Targeting α-synuclein for treatment of Parkinson’s disease: mechanistic and therapeutic considerations..
Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson’s disease.
C. Fidalgo, W.K.D. Ko, E. Tronci, Q. Li, R. Stancampiano, Q. Chuan, E. Bezard, M. Carta. Neuroscience. 2015-07-01. 298 : 389-396.
Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson’s disease..
Nikhil M. Urs, Simone Bido, Sean M. Peterson, Tanya L. Daigle, Caroline E. Bass, Raul R. Gainetdinov, Erwan Bezard, Marc G. Caron. Proc Natl Acad Sci USA. 2015-04-27. 112(19) : E2517-E2526.
Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function..
C. Hyacinthe, P. De Deurwaerdere, T. Thiollier, Q. Li, E. Bezard, I. Ghorayeb. Neuroscience. 2015-04-01. 290 : 621-635.
Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson’s disease?.
Erwan Bezard, Manolo Carta. Brain. 2015-02-05. 138(4) : 829-830.
Wireless neurosensor for full-spectrum electrophysiology recordings during free behavior..
Ming Yin, David A. Borton, Jacob Komar, Naubahar Agha, Yao Lu, Hao Li, Jean Laurens, Yiran Lang, Qin Li, Christopher Bull, Lawrence Larson, David Rosler, Erwan Bezard, Grégoire Courtine, Arto V. Nurmikko. Neuron. 2014-12-01. 84(6) : 1170-1182.
Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections..
Mohammadreza Shariatgorji, Anna Nilsson, Richard J.A. Goodwin, Patrik Källback, Nicoletta Schintu, Xiaoqun Zhang, Alan R. Crossman, Erwan Bezard, Per Svenningsson, Per E. Andren. Neuron. 2014-11-01. 84(4) : 697-707.
RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson’s disease..
Wai Kin D. Ko, Marie-Laure Martin-Negrier, Erwan Bezard, Alan R. Crossman, Paula Ravenscroft. Neurobiology of Disease. 2014-10-01. 70 : 138-148.
Down-regulating α-synuclein for treating synucleopathies..
Mathieu Bourdenx, Benjamin Dehay, Erwan Bezard. Mov Disord.. 2014-09-12. 29(12) : 1463-1465.
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death..
Slowing of neurodegeneration in Parkinson’s disease and Huntington’s disease: future therapeutic perspectives..
Anthony H V Schapira, C Warren Olanow, J Timothy Greenamyre, Erwan Bezard. The Lancet. 2014-08-01. 384(9942) : 545-555.
The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model..
Erwan Bezard, Elsa Y. Pioli, Qin Li, Françoise Girard, Vincent Mutel, Charlotte Keywood, Francois Tison, Olivier Rascol, Sonia M. Poli. Mov Disord.. 2014-05-27. 29(8) : 1074-1079.
Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia..
Michel Engeln, Philippe De Deurwaerdère, Qin Li, Erwan Bezard, Pierre-Olivier Fernagut. Cereb. Cortex. 2014-04-25. 25(9) : 2783-2792.
Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson’s disease..
Wai Kin D. Ko, Qin Li, Erwan Bezard. Neuroscience Letters. 2014-04-01. 566 : 72-76.
Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson’s disease..
Wai Kin D. Ko, Elsa Pioli, Qin Li, Steve McGuire, Audrey Dufour, Todd B. Sherer, Erwan Bezard, Maurizio F. Facheris. Mov Disord.. 2014-03-07. 29(6) : 772-779.
D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism..
Carole Hyacinthe, Quentin Barraud, François Tison, Erwan Bezard, Imad Ghorayeb. Neurobiology of Disease. 2014-03-01. 63 : 20-24.
Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson’s disease and l-DOPA-induced dyskinesia..
Mathieu Bourdenx, Anna Nilsson, Henrik Wadensten, Maria Fälth, Qin Li, Alan R. Crossman, Per E. Andrén, Erwan Bezard. Neurobiology of Disease. 2014-02-01. 62 : 307-312.
Depressive-like behavioral profiles in captive-bred single- and socially-housed rhesus and cynomolgus macaques: a species comparison..
Neurological drug development: a guide for a start-up biotech..
Thomas P. Blackburn, Erwan Bezard. Neurobiology of Disease. 2014-01-01. 61 : 1-5.
Erwan Bezard, Pierre-Olivier Fernagut. Parkinsonism & Related Disorders. 2014-01-01. 20 : S17-S19.
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia..
Erwan Bézard, Ana Muñoz, Elisabetta Tronci, Elsa Y. Pioli, Qin Li, Gregory Porras, Anders Björklund, Manolo Carta. Neuroscience Research. 2013-12-01. 77(4) : 242-246.
Birth origin differentially affects depressive-like behaviours: are captive-born cynomolgus monkeys more vulnerable to depression than their wild-born counterparts?.
Sandrine MJ. Camus, Céline Rochais, Catherine Blois-Heulin, Qin Li, Martine Hausberger, Erwan Bezard. PLoS ONE. 2013-07-04. 8(7) : e67711.
Levodopa-induced dyskinesias in the absence of nigrostriatal degeneration..
Erwan Bézard, C. Warren Olanow, José A. Obeso. Mov Disord.. 2013-06-20. 28(8) : 1023-1024.
Behavioural profiles in captive-bred cynomolgus macaques: towards monkey models of mental disorders?.
Sandrine M. J. Camus, Catherine Blois-Heulin, Qin Li, Martine Hausberger, Erwan Bezard. PLoS ONE. 2013-04-29. 8(4) : e62141.
Lysosomal impairment in Parkinson’s disease..
Benjamin Dehay, Marta Martinez-Vicente, Guy A. Caldwell, Kim A. Caldwell, Zhenyue Yue, Mark R. Cookson, Christine Klein, Miquel Vila, Erwan Bezard. Mov Disord.. 2013-04-11. 28(6) : 725-732.
Effects of memantine and galantamine on cognitive performance in aged rhesus macaques..
Jay S. Schneider, Elsa Y. Pioli, Yang Jianzhong, Qin Li, Erwan Bezard. Neurobiology of Aging. 2013-04-01. 34(4) : 1126-1132.
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia..
Erwan Bezard, Elisabetta Tronci, Elsa Y. Pioli, Qin Li, Gregory Porras, Anders Björklund, Manolo Carta. Mov Disord.. 2013-02-06. 28(8) : 1088-1096.
[PSD-95 expression controls L-Dopa dyskinesia]..
Matthieu Bastide, Erwan Bézard. Med Sci (Paris). 2013-02-01. 29(2) : 139-141.
Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model..
Jay S. Schneider, Elsa Y. Pioli, Yang Jianzhong, Qin Li, Erwan Bezard. Mov Disord.. 2012-12-12. 28(5) : 663-667.
Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate..
Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias..
M. Marti, D. Rodi, Q. Li, R. Guerrini, S. Fasano, I. Morella, A. Tozzi, R. Brambilla, P. Calabresi, M. Simonato, E. Bezard, M. Morari. Journal of Neuroscience. 2012-11-14. 32(46) : 16106-16119.
Experimental reappraisal of continuous dopaminergic stimulation against L-dopa-induced dyskinesia..
Erwan Bezard. Mov Disord.. 2012-11-09. 28(8) : 1021-1022.
Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson’s disease..
Cristina Miguelez, Stéphanie Morin, Audrey Martinez, Michel Goillandeau, Erwan Bezard, Bernard Bioulac, Jérôme Baufreton. The Journal of Physiology. 2012-09-25. 590(22) : 5861-5875.
Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove..
Benjamin Dehay, Marta Martinez-Vicente, Alfredo Ramirez, Celine Perier, Christine Klein, Miquel Vila, Erwan Bezard. Autophagy. 2012-09-14. 8(9) : 1389-1391.
A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale..
Susan H. Fox, Tom H. Johnston, Qin Li, Jonathan Brotchie, Erwan Bezard. Mov. Disord.. 2012-09-13. 27(11) : 1373-1378.
Animal models of Parkinson’s disease: limits and relevance to neuroprotection studies..
Erwan Bezard, Zhenyu Yue, Deniz Kirik, Maria Grazia Spillantini. Mov Disord. 2012-07-02. 28(1) : 61-70.
Localization of endogenous morphine-like compounds in the mouse spinal cord..
Alexis Laux, François Delalande, Jinane Mouheiche, Denise Stuber, Alain Van Dorsselaer, Enrica Bianchi, Erwan Bezard, Pierrick Poisbeau, Yannick Goumon. J. Comp. Neurol.. 2012-03-06. 520(7) : 1547-1561.
Toward an animal model of restless legs syndrome?.
Imad Ghorayeb, Erwan Bezard. Mov. Disord.. 2012-01-30. 27(3) : 337-338.
Functional connectivity in human and monkey brain: new insights for understanding movement disorders?.
Palma Pró-Sistiaga, Erwan Bézard. Mov. Disord.. 2012-01-01. 27(1) : 61-61.
Modeling Parkinson’s disease in primates: The MPTP model..
G. Porras, Q. Li, E. Bezard. Cold Spring Harbor Perspectives in Medicine. 2011-12-22. 2(3) : a009308-a009308.
Contribution of pre-synaptic mechanisms to L-DOPA-induced dyskinesia..
M. Carta, E. Bezard. Neuroscience. 2011-12-01. 198 : 245-251.
What should be said to the lay public regarding ADHD etiology..
Francois Gonon, Erwan Bezard, Thomas Boraud. Am. J. Med. Genet.. 2011-08-31. 156(8) : 989-991.
A new cerebral hemorrhage model in cynomolgus macaques created by injection of autologous anticoagulated blood into the brain..
Hua Zhu, Qin Li, Ming Feng, Yun-Xin Chen, Hao Li, Jin-Jiang Sun, Chun-Hua Zhao, Ren-Zhi Wang, Erwan Bezard, Chuan Qin. Journal of Clinical Neuroscience. 2011-07-01. 18(7) : 955-960.
A tale on animal models of Parkinson’s disease..
Erwan Bezard, Serge Przedborski. Mov. Disord.. 2011-05-01. 26(6) : 993-1002.
New animal models of Parkinson’s disease..
Benjamin Dehay, Erwan Bezard. Mov. Disord.. 2011-04-05. 26(7) : 1198-1205.
Misrepresentation of neuroscience data might give rise to misleading conclusions in the media: the case of attention deficit hyperactivity disorder..
Francois Gonon, Erwan Bezard, Thomas Boraud. PLoS ONE. 2011-01-31. 6(1) : e14618.
Migration and differentiation of human mesenchymal stem cells in the normal rat brain..
Jia-Mei Li, Hua Zhu, Shan Lu, Ying Liu, Qin Li, Paula Ravenscroft, Yan-Feng Xu, Lan Huang, Chun-Mei Ma, Erwan Bezard, Robert Chun-Hua Zhao, Ren-zhi Wang, Chuan Qin. Neurological Research. 2011-01-01. 33(1) : 84-92.
Protein aggregation in the aging retina..
François Leger, Pierre-Olivier Fernagut, Marie-Hélène Canron, Sandy Léoni, Claude Vital, François Tison, Erwan Bezard, Anne Vital. J Neuropathol Exp Neurol. 2011-01-01. 70(1) : 63-68.
Molecular mechanisms of l-DOPA-induced dyskinesia..
Gilberto Fisone, Erwan Bezard. International Review of Neurobiology. 2011-01-01. : 95-122.
Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis..
Michal Krawczyk, François Georges, Robyn Sharma, Xenos Mason, Amandine Berthet, Erwan Bézard, Éric C. Dumont. Journal of Neurophysiology. 2011-01-01. 105(1) : 145-153.
Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism..
Pierre-Olivier Fernagut, Quentin Barraud, Erwan Bezard, Imad Ghorayeb, Francois Tison. Neurological Research. 2010-12-01. 32(10) : 1050-1053.
Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate..
Quentin Barraud, Ibrahim Obeid, Incarnation Aubert, Gregory Barrière, Hugues Contamin, Steve McGuire, Paula Ravenscroft, Gregory Porras, François Tison, Erwan Bezard, Imad Ghorayeb. PLoS ONE. 2010-10-13. 5(10) : e13306.
[GRK6, a new therapeutic approach to alleviate L-dopa-induced dyskinesia]..
Amandine Berthet, Erwan Bézard. Med Sci (Paris). 2010-10-01. 26(10) : 800-803.
A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys..
Daniella Rylander, Hanna Iderberg, Qin Li, Andrzej Dekundy, Jinlan Zhang, Hao Li, Ren Baishen, Wojciech Danysz, Erwan Bezard, M. Angela Cenci. Neurobiology of Disease. 2010-09-01. 39(3) : 352-361.
Genes regulated in MPTP-treated macaques and human Parkinson’s disease suggest a common signature in prefrontal cortex..
Markus Storvik, Marie-Jeanne Arguel, Sandra Schmieder, Audrey Delerue-Audegond, Qin Li, Chuan Qin, Anne Vital, Bernard Bioulac, Christian E. Gross, Garry Wong, Jean-Louis Nahon, Erwan Bezard. Neurobiology of Disease. 2010-06-01. 38(3) : 386-394.
Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate..
Monty A. Silverdale, Christopher Kobylecki, Penelope J. Hallett, Qin Li, Anthone W. Dunah, Paula Ravenscroft, Erwan Bezard, Jonathan M. Brotchie. Synapse. 2010-02-01. 64(2) : 177-180.
Treating Parkinson’s disease: preserve the spines! (Commentary on Soderstrom et al.)..
Erwan Bezard. European Journal of Neuroscience. 2010-02-01. 31(3) : 477-477.
Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia..
Initial clinical manifestations of Parkinson’s disease: features and pathophysiological mechanisms..
Maria C Rodriguez-Oroz, Marjan Jahanshahi, Paul Krack, Irene Litvan, Raúl Macias, Erwan Bezard, José A Obeso. The Lancet Neurology. 2009-12-01. 8(12) : 1128-1139.
Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia..
Céline Guigoni, Erwan Bezard. Parkinsonism & Related Disorders. 2009-12-01. 15 : S64-S67.
Chronic dopaminergic stimulation in Parkinson’s disease: from dyskinesias to impulse control disorders..
Valerie Voon, Pierre-Olivier Fernagut, Jeff Wickens, Christelle Baunez, Manuel Rodriguez, Nancy Pavon, Jorge L Juncos, José A Obeso, Erwan Bezard. The Lancet Neurology. 2009-12-01. 8(12) : 1140-1149.
Dopamine receptors and L-dopa-induced dyskinesia..
Amandine Berthet, Erwan Bezard. Parkinsonism & Related Disorders. 2009-12-01. 15 : S8-S12.
Sleep disorders in Parkinson’s disease: the contribution of the MPTP non-human primate model..
Quentin Barraud, Virginie Lambrecq, Claude Forni, Steve McGuire, Michael Hill, Bernard Bioulac, Emmanuel Balzamo, Erwan Bezard, François Tison, Imad Ghorayeb. Experimental Neurology. 2009-10-01. 219(2) : 574-582.
Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease..
Olivier Berton, Céline Guigoni, Qin Li, Bernard H. Bioulac, Incarnation Aubert, Christian E. Gross, Ralph J. DiLeone, Eric J. Nestler, Erwan Bezard. Biological Psychiatry. 2009-09-01. 66(6) : 554-561.
The nigrostriatal pathway in Creutzfeldt-Jakob disease..
Anne Vital, Pierre-Olivier Fernagut, Marie-Hélène Canron, Julien Joux, Erwan Bezard, Marie-Laure Martin-Negrier, Claude Vital, François Tison. J Neuropathol Exp Neurol. 2009-07-01. 68(7) : 809-815.
The pathologic features of neurocutaneous melanosis in a cynomolgus macaque..
Y. Chen, W. Deng, H. Zhu, J. Li, Y. Xu, X. Dai, C. Jia, Q. Kong, L. Huang, Y. Liu, C. Ma, C. Xiao, Q. Li, E. Bezard, C. Qin. Vet Pathol. 2009-03-09. 46(4) : 773-775.
Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism..
t. chaumette, t. lebouvier, p. aubert, b. lardeux, c. qin, q. li, d. accary, e. bézard, s. bruley des varannes, p. derkinderen, m. neunlist. Neurogastroenterology & Motility. 2009-02-01. 21(2) : 215-222.
Priming for l-dopa-induced dyskinesia in Parkinson’s disease: a feature inherent to the treatment or the disease?.
Agnès Nadjar, Charles R. Gerfen, Erwan Bezard. Progress in Neurobiology. 2009-01-01. 87(1) : 1-9.
The vascular endothelial cell is a new origin of melanin pigment on cynomolgus macaque with neurocutaneous melanosis..
Chuan Qin, Hua Zhu, Yunxin Chen, Jiamei Li, Wei Deng, Yanfeng Xu, Xiaowei Dai, Chunshi Jia, Qi Kong, Lan Huang, Yali Liu, Chunmei Ma, Chong Xiao, Ying Liu, Qin Li, Erwan Bezard. Pigment Cell & Melanoma Research. 2008-12-01. 21(6) : 710-711.
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia..
A. Munoz, Q. Li, F. Gardoni, E. Marcello, C. Qin, T. Carlsson, D. Kirik, M. Di Luca, A. Bjorklund, E. Bezard, M. Carta. Brain. 2008-10-24. 131(12) : 3380-3394.
Striatal histone modifications in models of levodopa-induced dyskinesia..
Anthony P. Nicholas, Farah D. Lubin, Penelope J. Hallett, Padmapriya Vattem, Paula Ravenscroft, Erwan Bezard, Shaobo Zhou, Susan H. Fox, Jonathan M. Brotchie, J. David Sweatt, David G. Standaert. J Neurochem. 2008-07-01. 106(1) : 486-494.
Intratelencephalic corticostriatal neurons equally excite striatonigral and striatopallidal neurons and their discharge activity is selectively reduced in experimental parkinsonism..
Bérangère Ballion, Nicolas Mallet, Erwan Bézard, José Luis Lanciego, Francois Gonon. European Journal of Neuroscience. 2008-04-25. 27(9) : 2313-2321.
The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson’s disease..
S. Schuster, A. Nadjar, J. T. Guo, Q. Li, C. Ittrich, B. Hengerer, E. Bezard. Journal of Neuroscience. 2008-04-23. 28(17) : 4311-4316.
[Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure]..
Erwan Bezard. Med Sci (Paris). 2008-04-01. 24(4) : 368-368.
Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson’s disease..
Dieter Scheller, Christine Stichel-Gunkel, Hermann Lübbert, Gregory Porras, Paula Ravenscroft, Michael Hill, Erwan Bezard. Neuroscience Letters. 2008-02-01. 432(1) : 30-34.
Preclinical development of gene therapy for Parkinson’s disease..
Grégory Porras, Erwan Bezard. Experimental Neurology. 2008-01-01. 209(1) : 72-81.
RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson’s disease..
S. J. Gold, C. V. Hoang, B. W. Potts, G. Porras, E. Pioli, K. W. Kim, A. Nadjar, C. Qin, G. J. LaHoste, Q. Li, B. H. Bioulac, J. L. Waugh, E. Gurevich, R. L. Neve, E. Bezard. Journal of Neuroscience. 2007-12-26. 27(52) : 14338-14348.
Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson’s disease through inhibition of ROS-NO pathway..
Shuhong Guo, Jingqi Yan, Tangbin Yang, Xianqiang Yang, Erwan Bezard, Baolu Zhao. Biological Psychiatry. 2007-12-01. 62(12) : 1353-1362.
Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats..
P. Belujon, E. Bezard, A. Taupignon, B. Bioulac, A. Benazzouz. Journal of Neuroscience. 2007-09-05. 27(36) : 9595-9606.
Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson’s disease..
Dieter Scheller, Piu Chan, Qin Li, Tao Wu, Renling Zhang, Le Guan, Paula Ravenscroft, Celine Guigoni, Alan R. Crossman, Michael Hill, Erwan Bezard. Experimental Neurology. 2007-02-01. 203(2) : 415-422.
Shaping of motor responses by incentive values through the basal ganglia..
B. Pasquereau, A. Nadjar, D. Arkadir, E. Bezard, M. Goillandeau, B. Bioulac, C. E. Gross, T. Boraud. Journal of Neuroscience. 2007-01-31. 27(5) : 1176-1183.
Novel pharmacological targets for the treatment of Parkinson’s disease..
Anthony H. V. Schapira, Erwan Bezard, Jonathan Brotchie, Frédéric Calon, Graham L. Collingridge, Borris Ferger, Bastian Hengerer, Etienne Hirsch, Peter Jenner, Nicolas Le Novère, José A. Obeso, Michael A. Schwarzschild, Umberto Spampinato, Giora Davidai. Nat Rev Drug Discov. 2006-10-01. 5(10) : 845-854.
A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism..
Erwan Bezard. Behavioural Pharmacology. 2006-09-01. 17(5-6) : 379-382.
Traditional Chinese medicine for Parkinson’s disease: a review of Chinese literature..
Qin Li, Deming Zhao, Erwan Bezard. Behavioural Pharmacology. 2006-09-01. 17(5-6) : 403-410.
Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia..
A. Nadjar. Journal of Neuroscience. 2006-08-23. 26(34) : 8653-8661.
5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson’s disease..
Erwan Bezard, Irene Gerlach, Rosario Moratalla, Christian E. Gross, Reinhard Jork. Neurobiology of Disease. 2006-07-01. 23(1) : 77-86.
Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice..
Ainhoa Bilbao, Andrea Cippitelli, Ana Belén Martín, Noelia Granado, Oscar Ortiz, Erwan Bezard, Jiang-Fan Chen, Miguel Navarro, Fernando Rodríguez de Fonseca, R Moratalla. Psychopharmacology. 2006-02-10. 185(2) : 160-168.
The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders..
L. Leriche, E. Bezard, C. Gross, O. Guillin, B. Foll, J. Diaz, P. Sokoloff. CNSNDDT. 2006-02-01. 5(1) : 25-43.
Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: a proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson’s disease using DIGE..
Kim Kultima, Birger Scholz, Henrik Alm, Karl Skold, Marcus Svensson, Alan R Crossman, Erwan Bezard, Per E Andren, Ingrid Lonnstedt. BMC Bioinformatics. 2006-01-01. 7(1) : 475.
Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson’s disease..
F BASSILANA, N MACE, Q LI, J STUTZMANN, C GROSS, L PRADIER, J BENAVIDES, J MENAGER, E BEZARD. Neurobiology of Disease. 2005-10-01. 20(1) : 93-103.
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway..
Shuhong Guo, Erwan Bezard, Baolu Zhao. Free Radical Biology and Medicine. 2005-09-01. 39(5) : 682-695.
Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria..
Yu-Xiang Xie, Erwan Bezard, Bao-Lu Zhao. J. Biol. Chem.. 2005-06-27. 280(37) : 32405-32412.
Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors..
C. Guigoni, I. Aubert, Q. Li, V.V. Gurevich, J.L. Benovic, S. Ferry, U. Mach, H. Stark, L. Leriche, K. Håkansson, Bernard H. Bioulac, Christian E. Gross, Pierre Sokoloff, Gilberto Fisone, E.V. Gurevich, Bertrand Bloch, Erwan Bezard. Parkinsonism & Related Disorders. 2005-06-01. 11 : S25-S29.
Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson’s disease..
P.J. Hallett, A.W. Dunah, P. Ravenscroft, S. Zhou, E. Bezard, A.R. Crossman, J.M. Brotchie, D.G. Standaert. Neuropharmacology. 2005-03-01. 48(4) : 503-516.
L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain..
E. Bezard, C.E. Gross, Li Qin, V.V. Gurevich, J.L. Benovic, E.V. Gurevich. Neurobiology of Disease. 2005-03-01. 18(2) : 323-335.
Rise and fall of minocycline in neuroprotection: need to promote publication of negative results..
Elsa Diguet, Christian E. Gross, François Tison, Erwan Bezard. Experimental Neurology. 2004-09-01. 189(1) : 1-4.
Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys..
A. Hsu. Journal of Pharmacology and Experimental Therapeutics. 2004-08-05. 311(2) : 770-777.
Deleterious effects of minocycline in animal models of Parkinson’s disease and Huntington’s disease..
Elsa Diguet, Pierre-Olivier Fernagut, Xing Wei, Yansheng Du, Richard Rouland, Christian Gross, Erwan Bezard, François Tison. European Journal of Neuroscience. 2004-06-01. 19(12) : 3266-3276.
Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson’s disease..
M. P. Hill. Journal of Pharmacology and Experimental Therapeutics. 2004-04-02. 310(1) : 386-394.
High frequency stimulation of the entopeduncular nucleus has no effect on striatal dopaminergic transmission..
Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque..
Erwan Bezard, Michael P. Hill, Alan R. Crossman, Jonathan M. Brotchie, Anne Michel, Renee Grimée, Henrik Klitgaard. European Journal of Pharmacology. 2004-02-01. 485(1-3) : 159-164.
Neuroprotective agents for clinical trials in Parkinson’s disease: a systematic assessment..
E. Diguet, C. E. Gross, E. Bezard, F. Tison, N. Stefanova, G. K. Wenning, B. Ravina, S. Fagan, R. Hart, C. Hovinga, D. Murphy, T. Dawson, J. Marler. Neurology. 2004-01-12. 62(1) : 158-159.
Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway..
Oliver Guillin, Nathalie Griffon, Jorge Diaz, Bernard Le Foll, Erwan Bezard, Christian Gross, Chris Lammers, Holger Stark, Patrick Carroll, Jean-Charles Schwartz. International Review of Neurobiology. 2004-01-01. : 425-444.
Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets..
Michael P Hill, Jonathan M Brotchie, Alan R Crossman, Erwan Bezard, Anne Michel, Renee Grim??e, Henrik Klitgaard. Clinical Neuropharmacology. 2004-01-01. 27(4) : 171-177.
Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson’s disease..
Olivier Guillin, Nathalie Griffon, Erwan Bezard, Ludovic Leriche, Jorge Diaz, Christian Gross, Pierre Sokoloff. European Journal of Pharmacology. 2003-11-01. 480(1-3) : 89-95.
Electrophysiological and metabolic evidence that high-frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata..
CHUN-HWEI TAI, THOMAS BORAUD, ERWAN BEZARD, BERNARD BIOULAC, CHRISTIAN GROSS, ABDELHAMID BENAZZOUZ. The FASEB Journal. 2003-10-01. 17(13) : 1820-1830.
Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset..
Michael P. Hill, Erwan Bezard, Steven G. McGuire, Alan R. Crossman, Jonathan M. Brotchie, Ann Michel, Renee Grimée, Henrik Klitgaard. Mov. Disord.. 2003-08-21. 18(11) : 1301-1305.
Neuroprotection for Parkinson’s disease: a call for clinically driven experimental design..
Erwan Bezard. The Lancet Neurology. 2003-07-01. 2(7) : 393.
Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT..
Caroline Prunier, Erwan Bézard, Jérôme Montharu, Marina Mantzarides, Jean-Claude Besnard, Jean-Louis Baulieu, Christian Gross, Denis Guilloteau, Sylvie Chalon. NeuroImage. 2003-07-01. 19(3) : 810-816.
Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei..
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function..
Erwan Bézard, Sandrine Ferry, Ulrich Mach, Holger Stark, Ludovic Leriche, Thomas Boraud, Christian Gross, Pierre Sokoloff. Nat Med. 2003-05-12. 9(6) : 762-767.
Presymptomatic compensation in Parkinson’s disease is not dopamine-mediated..
Erwan Bezard, Christian E. Gross, Jonathan M. Brotchie. Trends in Neurosciences. 2003-04-01. 26(4) : 215-221.
Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson’s disease..
From single extracellular unit recording in experimental and human Parkinsonism to the development of a functional concept of the role played by the basal ganglia in motor control..
Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross. Progress in Neurobiology. 2002-03-01. 66(4) : 265-283.
Pathophysiology of levodopa-induced dyskinesia: potential for new therapies..
Erwan Bezard, Jonathan M. Brotchie, Christian E. Gross. Nat Rev Neurosci. 2001-08-01. 2(8) : 577-588.
Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys..
Erwan Bezard, Paula Ravenscroft, Christian E. Gross, Alan R. Crossman, Jonathan M. Brotchie. Neurobiology of Disease. 2001-04-01. 8(2) : 343-350.
Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey..
Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross. Brain. 2001-03-01. 124(3) : 546-557.
Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey..
E Bezard, T Boraud, S Chalon, J.M Brotchie, D Guilloteau, C.E Gross. Neuroscience. 2001-02-01. 103(1) : 117-123.
Spontaneous long-term compensatory dopaminergic sprouting in MPTP-treated mice..
Erwan Bezard, Sra Dovero, Christelle Imbert, Thomas Boraud, Christian E. Gross. Synapse. 2000-12-01. 38(3) : 363-368.
Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse..
Erwan Bezard, Mohamed Jaber, François Gonon, Alain Boireau, Bertrand Bloch, Christian E. Gross. European Journal of Neuroscience. 2000-08-01. 12(8) : 2892-2900.
Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration..
Imad Ghorayeb, Pierre O. Fernagut, Incarnation Aubert, Erwan Bezard, Werner Poewe, Gregor K. Wenning, Fran�ois Tison. Mov. Disord.. 2000-05-01. 15(3) : 531-536.
Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey..
Christelle Imbert, Erwan Bezard, Stéphane Guitraud, Thomas Boraud, Christian E Gross. Journal of Neuroscience Methods. 2000-03-01. 96(1) : 71-76.
Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey..
Th Boraud, E Bezard, J.M Stutzmann, B Bioulac, C.E Gross. Neuroscience Letters. 2000-03-01. 281(2-3) : 75-78.
From experimentation to the surgical treatment of Parkinson’s disease: prelude or suite in basal ganglia research?.
C Gross. Progress in Neurobiology. 1999-12-01. 59(5) : 509-532.
Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey..
Erwan Bezard, Christine Brefel, Francois Tison, Helene Peyro-SaintPaul, Philippe Ladure, Olivier Rascol, Christian E. Gross. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1999-10-01. 23(7) : 1237-1246.
Trichloroethylene and parkinsonism: a human and experimental observation..
Dominique Guehl, Erwan Bezard, Sandra Dovero, Thomas Boraud, Bernard Bioulac, Christian Gross. Eur J Neurol. 1999-09-01. 6(5) : 609-611.
Cortical stimulation and epileptic seizure: a study of the potential risk in primates..
Erwan Bezard, Thomas Boraud, Jean-Paul Nguyen, Francisco Velasco, Yves Keravel, Christian Gross. Neurosurgery. 1999-08-01. 45(2) : 346-350.
Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms..
Erwan Bezard, Thomas Boraud, Bernard Bioulac, Christian E. Gross. European Journal of Neuroscience. 1999-06-01. 11(6) : 2167-2170.
Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model..
Erwan Bezard, Jean-Marie Stutzmann, Christelle Imbert, Thomas Boraud, Alain Boireau, Christian E. Gross. European Journal of Pharmacology. 1998-09-01. 356(2-3) : 101-104.
Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach..
Erwan Bezard, Christian E Gross. Progress in Neurobiology. 1998-06-01. 55(2) : 93-116.
Glutamatergic compensatory mechanisms in experimental parkinsonism..
Erwan Bezard, Bernard Bioulac, Christian E. Gross. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1998-05-01. 22(4) : 609-623.
Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey..
Th Boraud, E Bezard, D Guehl, B Bioulac, Ch Gross. Brain Research. 1998-03-01. 787(1) : 157-160.
Experimental models of Parkinson’s disease: from the static to the dynamic..
Effects of different schedules of MPTP administration on dopaminergic neurodegeneration in mice..
Erwan Bezard, Sandra Dovero, Bernard Bioulac, Christian Gross. Experimental Neurology. 1997-11-01. 148(1) : 288-292.
Kinetics of nigral degeneration in a chronic model of MPTP-treated mice..
Erwan Bezard, Sandra Dovero, Bernard Bioulac, Christian E Gross. Neuroscience Letters. 1997-09-01. 234(1) : 47-50.
Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism..
E Bezard, T Boraud, B Bioulac, C.E Gross. Neuroscience. 1997-09-01. 81(2) : 399-404.
A chronic MPTP model reproducing the slow evolution of Parkinson’s disease: evolution of motor symptoms in the monkey..
Erwan Bezard, Christelle Imbert, Xavier Deloire, Bernard Bioulac, Christian E Gross. Brain Research. 1997-08-01. 766(1-2) : 107-112.
Subthalamic stimulation elicits hemiballismus in normal monkey..
Corinne Beurrier, Erwan Bezard, Bernard Bioulac, Christian Gross. NeuroReport. 1997-05-01. 8(7) : 1625-1629.
Presymptomatic revelation of experimental parkinsonism..
Erwan Bezard, Thomas Boraud, Bernard Bioulac, Christian E. Gross. NeuroReport. 1997-01-01. 8(2) : 435-438.
High frequency stimulation of the internal Globus Pallidus (GPi) simultaneously improves parkinsonian symptoms and reduces the firing frequency of GPi neurons in the MPTP-treated monkey..
Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian Gross. Neuroscience Letters. 1996-08-01. 215(1) : 17-20.

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