Source: http://www.biocentras.lt/en/veikla/projects-scientific-publications/
Timestamp: 2019-04-21 16:04:05+00:00

Document:
Total project value: 3 803 925€. , EU contribution: 3 457 602,5 €.
Short introduction of project idea: US4GREENCHEM aims to design a biorefinery concept for the complete valorization of lignocellulosic biomass that is energy- and cost- efficient and based solely on green technologies. The concept combines mechanical pretreatment of the substrate with the aid of ultrasound to overcome its recalcitrance and disrupt inhibitors with mild CO2 hemicellulose degradation and with the enzymatic recovery of sugars and technologies for the valorization of the byproducts released in the process.
Total project value: 1 238 408 €, up to 499 175 € EU contribution.
Short introduction of project idea: To design and develop a pilot plant, with a treatment capacity of 5000 dm3 per hour, which will be able to remove between 97% and 99% of hydrocarbons, oil and fats from wastewater.
Sum of the financial support: total project budget 370 000 €.
Brief introduction of the Project idea: New inexpensive and effective technology for grease waste treatment in environment has been developed. According this technology, grease from effluent at first is removed mechanically and then they are degraded biologically with active micro organisms.
Short introduction of project idea: The successfully implemented SORBENT project had led to the development of the novel cost-efficient SORBENT soil remediation technique consisting of 3 individual components: SORBENT system, SORBENT bacterial preparation and phyto-remediation. Thus the SORBENT-DEMO project is targeted to full-scale demonstration of the novel SORBENT soil remediation technique applied in-situ to sites contaminated with heavy hydrocarbon mixtures.
Total project value: 1 989 118 Lt, i.e. up to 895 103 Lt from the foundation and 1 094 015 Lt from the funds of JSC „Biocentras“.
Short introduction of project idea: Perform research work with the purpose of creation of a complex of proteolytic enzymes, possessing unique properties for its subsequent use in innovative medical devices and cosmetic products.
Total project value: 1 407 325 Lt, i.e. up to 985 127 Lt from the foundation and 422 198 Lt from the funds of JSC „Biocentras“.
Short introduction of project idea: Creation of microcapsulation research centre for biologically active products, where technologies for biologically active preparations and new commercially applicable forms of prototype preparations created by the company will be developed.
Total project value: 1 740 232 Lt, i.e. up to 1 104 555 Lt from the foundation and 635 677 Lt from the funds of JSC „Biocentras“.
Total sum of the project: 1 310 678 €.
Brief introduction of the Project idea: To develop a demonstrative pilot plant for anaerobic digestion of manure from a single medium farm in order to get a good management of manure and energetic valorisation of wastes as well as to obtain a valorised fertiliser.
Total sum of the project: 491 389 Lt.
Brief introduction of the project idea: To select acido-lactic bacteria with the highest level of antimicrobial activity with purpose to treat seeds of various crops, to develop a new bioproduct technology and perform field tests with the assessment of the impact of the new bioproduct on the wellness of seeds.
Total sum of the project: 448 398 Lt.
Brief introduction of the project idea: To develop plant scale technologies for bioesters production for manufacturing a high value-added products.
Total sum of the project: 1 242 468 €.
Brief introduction of the Project idea: To develop two biotechnological processes at semi-industrial scale in order to produce two different classes of bio-products, bio-surfactants and ester oils (non useful for biodiesel production).
Sum of the financial support: 1 392 639 € support from the program, 485 279 € JSC “Biocentras” share.
Brief introduction of the Project idea: To develop and test new, reliable and economical technology for the clean-up of the soil contaminated with heavy oil fractions.
Sum of the financial support: 758 784 Lt support from the fund, 832 346 Lt from JSC “Biocentras” finances.
Brief introduction of the project idea: To develop original novel complex technology, based on high biotechnologies, for the clean-up of the various waste with keratins, which could be used for the development of the new products and introduction them to the market.
Brief introduction of the Project idea: During the project, biotechnological synthesis from oils, grease and other renewable sources is being researched. Most perspective synthesis processes are selected and manufacturing technologies to obtain and evaluate the experimental production – controllable flammability ageing-resistant biodegradable esters, are introduced. Suitability of the esters is examined in two areas: as plasticizers, used in plastic production, and like basic lubricants, used in bio lubricants.
Sum of the financial support: finance from fund 56 218 Lt, finance from JSC “Biocentras” 56 218 Lt.
Brief introduction of the Project idea: Technical opportunity research has been prepared for the help of the R&D practice: to develop original novel complex technology, based on high biotechnologies, for the clean-up of the various waste with keratins, which could be used for the development of the new products and introduction them to the market.
Sum of the financial support: finance from fund 880 000 Lt, finance from JSC “Biocentras” 400 000 Lt.
Brief introduction of the Project idea: New protein medicinal preparation has been developed, characterized with hemopoietic activity, which means that in human organism it stimulates the growth of blood cells like granulocytes and monocytes that protects the organism from bacterial infections.
Sum of the financial support: total project budget 450 000 €.
Brief introduction of the Project idea: Complex information technologies system for accidents prevention and accidents consequences clean-up has been developed. It enables to evaluate the volume of the accident very quickly and to choose optimal solutions for the liquidation of the accident consequences. System is dedicated for large companies that have a risk for pollution spill to the environment or for those, which clean-up pollution from the soil and water.
Sum of the financial support: total project budget 1 634 816 €, 193 646 € JSC “Biocentras” finance.
Brief introduction of the Project idea: Novel ultimate pressure dressing system for the treatment of venous ulcers has been developed. It reduces patients’ treatment time and cheapens venous treatment process.
Sum of the financial support: total project budget 763 768 €, 173 135 € JSC “Biocentras” finance.
Brief introduction of the Project idea: New, reliable and economical system for purification of the heavily polluted leachate has been developed.
Sum of the financial support: total project budget 750 000 €.
Brief introduction of the Project idea: Complex technology for clean-up of the polluted soil has been developed and optimized. According to this technology, migrating fraction of the contaminated oil is separated with bio-surfactants, whereas non-migrating fraction is neutralized with active micro organisms.
Sum of the financial support: 180 000 € JSC “Biocentras” finance.
Brief introduction of the Project idea: New economical and effective absorbent for a clean-up of the polluted oil reservoirs, sewage and gas has been developed.
Aikaitė-Stanaitienė, J.; Grigiškis, S.; Levišauskas, D.; Čipinytė, V.; Baškys, E. V.; Kačkytė, V. 2010. Development of fatty waste composting technology using bacterial preparation with lipolytic activity, Journal of Environmental Engineering and Landscape Management 18(4): 296–305. ISSN 1648-6897.
Javmen A, Grigiškis S, Rudenkov M, Pelišauskaitė E (2013). Saccharomicies cerevisiae yeast growth conditions optimisation using RSM methodology for the production of beta-glucan. Minerva Biotech 25: 227-234.
Javmen, A.: Nemeikaitė-Čenienė, Bratchikov, M.: Grigiškis, S.:, Grygas, F.: Jonauskienė, I.: Zabulytė, D.: Mauricas, M., 2015. Β-glucan from Saccharomyces cerevisiae Induces IFN-ϒ Production In Vivo in BALB/c Mice. In Vivo. (29), 359-364. ISSN:0258-851X.
Kačkytė, V.; Grigiškis, S.; Paliulis, D.; Aikaitė-Stanaitienė, J. 2011. Usage of plants for fat polluted soil treatment, Journal of Environmental Engineering and Landscape Management. 19(4):316-325. ISSN 1648-6897.
Levišauskas, D.; Galvanauskas, V.; Čipinytė, V.; Grigiškis, S. 2009. Optimization of fed-rate in fed-batch culture Enterobacter aerogenes 17 E13 for maximization of biomass productivity, Information Technology and Control 38(2): 102–107. ISSN 1392-124X.
Levišauskas, D.; Galvanauskas, V.; Žunda, G.; Grigiškis, S. 2004a. Model-based optimization of biosurfactants production in fed-batch culture Azotobacter vinelandii, Biotechnology Letters 26(14): 1141–1146. ISSN 0141-5492.
Matikevičienė, V.; Grigiškis, S.; Levišauskas, D.; Kinderytė, O.; Baškys, E. 2012. Technology for Treatment of Lipid-Rich Wastewater and Pipelines Clogged by Lipids Using Bacterial Preparation, Journal of Environmental Engineering and Landscape Management (in press). ISSN 1648-6897.
Asadauskas, S.; Griguceviciene, A.; Moroz, J.; Grigiskis, S.; Tvaska, B. 2009. Volatility and oxidative degradation of biotechnologically synthesized esters for utilization as plasticizers, in Polymer Chemistry and Technology: Proceedings of Scientific Conference Chemistry and Chemical Technology (22 April 2009, Kaunas, Lithuania), Kaunas: Technologija, 6–10. ISSN 2029-2457.
Grigiškis, S.; Cipinyte, V. 1998. Implications of selected bacterial strains for contamination of oil pollutants in soil and water in Environmental Contamination and Remediation Practices at Former and Present Military Bases. Series 2: Environmental security (12–17 October 1997, Vilnius, Lithuania), Vol. 48. Dordrecht: Kluwer Academic Publishers, 277–281. ISBN 0-7923-5247-5.
Čipinytė, V.; Grigiškis, S. 2000a. Naftą skaidančių mikroorganizmų atranka, Cheminė technologija 2(15): 65-69. ISSN 1392-1231.
Čipinytė, V.; Grigiškis, S.; Baškys, E. 2009. Selection of fat-degrading microorganisms for the treatment of lipids contaminated environment, Biologija 55(3–4): 84–92. ISSN 1392-0146.
Čipinytė, V.; Grigiškis, S.; Špokienė, A.; Baškys, E. V.; Vilutis, K. 1995. Žemos temperatūros įtaka naftos mikrobiologinio degradavimo procesui, Cheminė technologija 1: 69–73. ISSN 1392-1231.
Gylienė O., Aikaitė J., Šalkauskas M. Rückgewinnung von EDTA aus wässrigen Lösungen in Form von schwerlöslichem Cu2EDTA•4H2O, Galvanotechnik, 2001, 92, Nr. 8, 2222-2225.
Gylienė O., Aikaitė J. Formation of Binuclear EDTA and Cu(II) Complexes in Aqueous solutions. Polish Journal of Chemistry, 2003, vol. 77(1), p. 99-104.
Гилене О., Айкайте И., Нивинскене О. Осаждение ЭДТА из комплексных растворов тяжелых металлов и его регенерирование. Технология и конструирование в электронной аппаратуре, 2004, № 4, с. 54-56.
Gylienė O., Aikaitė J., Nivinskienė O. Recycling of Ni(II)-citrate complexes using precipitation in alkaline solutions. Journal of Hazardous Materials, Volume 109, Issues 1-3, 18 June 2004, Pages 105-111.
Gylienė O., Aikaitė J., Nivinskienė O. Recovery of EDTA from complex solutions using Cu(II) as precipitant and Cu(II) subsequent removal by electrolysis. Journal of Hazardous Materials. 2004; vol.116, Issue 1-2, p. 119-124.
Grigishkis, S.; Chipinyte, V.; Telysheva, G.; Bashkys, E. 2002. Degradation of crude oil and fuel oil (mazut) in soil by Arthrobacter strains and their association, Latvian Journal of Chemistry 3: 295–302. ISSN 0868-8249.
Grigiškis, S.; Čipinytė, V.; Levišauskas, D.; Baškys, E. V. 2005. Optimization of the Arthrobacter sp. cultures for degradation of the oil hydrocarbons, Latvian Journal of Chemistry 1: 263–271. ISSN 0868-8249.
Grigiškis, S., Samsonenko, J.; Baškys, E. V.; Čipinytė, V.; J., Tely­sheva, G.; Dizhbite, T.; Jashina, L. 2010. Immobilization of lipase from Enterobacter aerogenes E13 on modified lignins to obtain a novel biocatalyst, Cheminė technologija 54(1): 47–55. ISSN 1392-1231.
Juciūnas, A.; Grigiškis, S.; Baškys, E. 2011. Immobilization of Enterobacter aerogenes E13 strain culture medium, distinguished by its lipase activity, in the ethylcellulose microcapsules, Biologija 57(1): 26–32. ISSN 1392-0146.
Levišauskas, D.; Tekorius, T.; Čipinytė, V.; Grigiškis, S. 2004b. Experimental optimization of nutrient media for cultivation of Arthrobacter bacteria, Latvian Journal of Chemistry 1: 75–80. ISSN 0868-8249.
Neiberte B., Zakis G., Čipinite V., Grigiškis S. Aminolignins – active sorbents for heavy metal ions from waste waters. Latvian Journal of Chemistry 1 (2001) 68 – 70. ISSN 0868-8249.
Baškys, E.; Grigiškis, S.; Levišauskas, D.; Kildišas,V. 2004b. Influence of lignin products on efficiency of bioremediation of contaminated ecosystem objects, Aplinkos tyrimai, inžinerija ir vadyba 4(30): 78–81. ISSN 1392-1649.
Čipinytė, V.; Grigiškis, S. 2000b. Naftos ir jos produktų skaidymo naftą oksiduojančių mikroorganizmų asociacijomis tyrimas, Aplinkos inžinerija, 8(2): 74–79. ISSN 1392–1622.
Grigiškis, S.; Žunda, G. 2001. Paviršinio aktyvumo medžiagų (PAM) panaudojimas nafta ir jos produktais užterštam gruntui valyti, Aplinkos inžinerija 9(1): 17–22. ISSN 1392–1622.
Kildišas, V.; Levišauskas, D.; Grigiškis, S.; Baškys, E. 2003. Development of Clean-up Complex technology of soil contaminated by oil pollutants based on cleaner production concepts, Aplinkos tyrimai, inžinerija ir vadyba 3: 87–93. ISSN 1392-1649.
Levišauskas, D.; Brazauskas, K.; Chvostova, O.; Baškys, E.; Grigiškis, S. 2004c. Optimization of technological parameters of the contaminated soil washing technology, Aplinkos tyrimai, inžinerija ir vadyba 4: 55–60. ISSN 1392-1649.
Celiešiūtė, R.; Grigiškis, S.; Čipinytė, V. 2009. Biological surface active compounds application possibilities and selection of strain with emulsifying activity, in Environment. Technology. Resources: Proceedings of the 7th International Scientific and Practical Conference (25-27 June 2009, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 267–272. ISNN 1691-5402.
Čipinytė, V.; Grigiškis, S.; Šapokaitė, D.; Baškys, E. V. 2011. Production of biosurfactants by Arthrobacter sp. N3, a hydrocarbon degrading bacterium, in Environment. Technology. Resources: Proceedings of the 8th International Scientific and Practical Conference (20–22 June 2011, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 68–75. ISSN 1691-5402.
Dižavičienė, O., Grigiškis, S., Ančenko, O., Aikaitė-Stanaitienė, J. 2012. Application of keratinaze for complex keratin-fat waste composting research, Chemistry and Chemical Technology of Inorganic materials: Proceedings of Scientific Conference, Chemistry and Chemical Technology. ISSN 2029–9222.
Fatajeva, E., Žėkaitė, G., Grigiškis, S., Aikaitė – Stanaitienė, J. 2012. The cleaning of sea water contaminated with oil hydrocarbons, Chemistry and Chemical Technology of Inorganic materials: Proceedings of Scientific Conference, Chemistry and Chemical Technology. ISSN 2029–9222.
Gailiūtė, I.; Grigiškis, S.; Žėkaitė, G.; Čipinytė, V. 2011. Selection of microbes and conditions that induced bio-cracking of branched hydrocarbon squalane, in Environment. Technology. Resources: Proceedings of the 8th International Scientific and Practical Conference (20–22 June 2011, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 46–52. ISSN 1691-5402.
Grigiškis, S.; Baškys, E. V.; Levišauskas, D.; Kavaliauskė, M.; Dižavičienė, O.; Aikaitė-Stanaitienė, J. 2011. Optimization of sorbent system from paper mill waste short fibers for bioremediation of heavy hydrocarbons, in Environment. Technology. Resources: Proceedings of the 8th International Scientific and Practical Conference (20–22 June 2011, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 104–111. ISSN 1691-5402.
Mališauskienė, G., Grigiškis., S., Tvaska, B., Aikaitė – Stanaitienė., J. 2012. Synthesis of oleyl alkohol esters using different lipase types. Chemistry and Chemical Technology of Inorganic materials: Proceedings of Scientific Conference, Chemistry and Chemical Technology. P. 144 – 149. ISSN 2029–9222.
Matikevičienė, V., Grigiškis, S., Tvaska, B., Kadikinė, M., Aikaitė – Stanaitienė, J. 2012. Stabilization of keratinase preparations from Bacillus subtilis 103 and Actinomyces fradiae 119 strains. Chemistry and Chemical Technology of Inorganic materials: Proceedings of Scientific Conference, Chemistry and Chemical Technology. P. 150 – 155. ISSN 2029–9222.
Matikevičienė, V.; Grigiškis, S.; Levišauskas, D.; Sirvydytė, K.; Dižavičienė, O.; Masiliūnienė, D.; Ančenko, O. 2011. Optimization of keratinase production by Actinomyces fradiae 119 and its application in degradation of keratin containing wastes, in Environment. Technology. Resources: Proceedings of the 8th International Scientific and Practical Conference (20–22 June 2011, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 294–300. ISSN 1691-5402.
Matikevičienė, V.; Masiliūnienė, D.; Grigiškis, S. 2009. Degradation of keratin containing wastes by bacteria with keratinolytic activity, in Environment. Technology. Resources: Proceedings of the 7th International Scientific and Practical Conference (25–27 June 2009, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 284–289. ISNN 1691-5402.
Sirvydytė, K., Grigiškis, S., Masiliūnienė, D., Ančenko, O., Aikaitė – Stanaitienė, J.2012. The study of keratin degrading B. subtilis 103 and A. fradiae 119 strains interactions with fat degrading E. aerogenes E13 strain. Chemistry and Chemical Technology of Inorganic materials: Proceedings of Scientific Conference, Chemistry and Chemical Technology. P. 133 – 137. ISSN 2029–9222.
Telysheva, G.; Dizhbite, T.; Lebedeva, G.; Jashina, L.; Solodovnik, V.; Mutere, O.; Grigiškis, S.; Baškys, E. V.; Aikaitė-Stanaitienė, J. 2011. Use of plants to remediate soil polluted with oil, in Environment. Technology. Resources: Proceedings of the 8th International Scientific and Practical Conference (20–22 June 2011, Rezekne, Latvia). Rezekne: RA Izdevniecība. Vol. 1: 38–45. ISSN 1691-5402.
Grigiškis, S.; Baškys, E.V.; Vilutis, K. 1994 12 25. Naftos teršalus degraduojantis mikroorganizmas Azotobacter vinelandii 21. LR valstybinis patentų biuras Nr. 3111 B.
Grigiškis, S.; Baškys, E.V.; Špokienė, A.O. 1994 12 25. Aplinkos, užterštos angliavandeniliais, valymo būdas. LR valstybinis patentų biuras Nr. 3112 B.
Baskys, E.V.; Grigiskis, S.; Vilutis, K. 1996 02 27. Method of decomposition of a hydrocarbonpolluted environment by the use of bacterial compositions. USA patent No. 5 494 580.
Grigiškis, S.; Čipinytė, V.; Tvaska, B.; Urbanavičiūtė, I.; Rimdeika, R.; Mauricas, M. 2015 07 27. Fermentų kompleksų išskyrimas iš Steptomyces gougerotii 101, daugiafermentinių biopreparatų ruošimas bei taikymas. LR valstybinis patentų biuras, Nr. LT 6177 B.
Grigiškis, S.; Javmen, A.; Mauricas, M.; Čipinytė, V.; Kačanauskas, D.; Grygas, F.; Vaitoška, J. 2015 04 27. Terapinė ß-gliukanų kompozicija, moduliuojanti žmogaus imuninę sistemą ir inicijuojanti vėžinių ląstelių ardymą. LR valstybinis patentų biuras, Nr. LT 6145 B.
Grigiškis, S.; Čipinytė, V.; Vaitoška, J.; Aikaitė – Stanaitienė, J.; Gailiūtė, I.; Račkauskienė, G.; Grygas, F. 2015 06 25. Kompleksinis aplinkos valymo nuo naftos teršalų būdas. LR valstybinis patentų biuras, Nr. LT 6162 B.
Juodeikienė, G.; Kalėdienė, L.; Grigiškis, S.; Bašinskienė, L. 2015 04 27. Sėklinių grūdų ir sėklų apdorojimo būdas. LR valstybinis patentų biuras, Nr. LT 6142 B.
JSC “Biocentras” bacterial preparations and technologies of their use are covered by Patents of Lithuania (1992) No 3111B and (1992) No 3112B and Patent of USA (1996) No 5494580, all owned by JSC “Biocentras”.
Projects of European Research and Developments Cooperation Program “Eureka”, International Programs 5 Framework and 6 Framework, in which company take part are covered by laws of EU.
The purchase price paid for the JSC “Biocentras” preparations and technology by end users grants them a non-transferable, non-exclusive license to use preparations and technology for their needs only, not for resale. A separate commercial license is available from JSC “Biocentras” for commercial uses or applications.

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