Source: http://en.allokin.ru/genital-herpes/suschestvuyuschie-metody-lecheniya/
Timestamp: 2019-04-21 07:14:35+00:00

Document:
Currently, a large quantity of drugs for the treatment of herpetic infection have been developed and applied, a common disadvantage of which is the inability to conduce to clinical cure. The effect of antiviral therapy has usually a short duration.
The main part of antiherpetic drugs is more active during the acute period of recurrent Genital Herpes, because they mainly affect the replication process of the virus and have a small effect on a remission duration. Often the recurrences are occurred again with the same frequency at drug withdrawal. The resistance can be developed to some antiviral drugs. Currently, only 27% of patients diagnosed with Genital Herpes get an antiviral therapy. According to some authors, about 95% of patients with clinical manifestations of Genital Herpes do not get any treatment.
The use of chemotherapeutic drugs, possessing antiherpetic activity, showed that jugulating quickly and effectively the acute symptoms of HI, they do not prevent the recurrence of HI and in some cases even do not reduce their frequency, because they obrigate only the active replication of herpes viruses. So one-time (a course) use of drugs of this group does not prevent the development of the recurrent disease, the infection with a related or new type of herpesvirus, does not affect the immune parameters (V. A. Isakov etc., 1993; L. N. Khakhalin, 1997).
During last years, there have been reports indicating the possibility of forming resistant strains of HSV with using AC. And resistant to AC strains of the herpes virus are mostly often allocated in patients with herpetic pneumonia, encephalitis, skin-mucous form of the HI on the background of evident immunodeficiency.
Certain difficulties are associated with the treatment of patients with frequently Recurrent Genital Herpes (RGH), due to the variety of HV and their pantropical base, the complexity of the developing mechanisms and, course of, the disease, development of resistant to the basic drugs of herpes viruses strains. Therefore, the introduction of a new drug (Allokin-alpha), having a stimulating effect on interferon status and T - cell immunity can be an important link in enhancing the effectiveness of herpes therapy. (F. I. Ershov etc., 2003; V. A. Isakov and others, 2006).
A guide for doctors "Application of Allokine-alfa in the treatment of viral infections" F. I. Ershov, V. A. Isakov, G. P. Becker, M. Y. Serebryakov, T. V. Sologub, N. B. Serebryanaya, M. S. Tischenko, S. I. Chernysh 2008, p. 38.
"Clinical efficiency and mechanism of action of Allokine-alpha at patients with recurrent Genital Herpes" F. I. Ershov, A. A. Kubanova, A. E. Shulzhenko, B. V. Pinegin, G. P. Becker, S. I. Chernysh, L. V. Bugaev.
"Using Allokin-alpha in therapy of simplex and Herpes Zoster" by V. A. Isakov, V. N. Koryagin, G. P., Becker, M. Y. Serebryakov.
"New ways of herpes infections treatment" N. B. Silver, Egorova V. N.
"THE EFFECT OF THE THERAPY WITH ALLOKINE-ALPHA® ON THE COURSE OF LONG-LASTING RECURRENCE OF GENITAL HERPES" F. I. Ershov, A. A. Kubanova, B. V. Pinegin, A. E. Shulzhenko, G. P. Becker, S. I. Chernysh, L. V. Bugaev.

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