Source: https://apemm.org/index.php/actualites/publications/243-les-recentes-publications-des-chercheurs-de-l-institut-cochin-2018-2019
Timestamp: 2019-04-22 22:37:12+00:00

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Niedergang, F.Dendritic cells mature to resist lamin degradation and herpes virus release. J Cell Biol 2019 218:387-388.
Cecon, E., A. Ivanova, M. Luka, F. Gbahou, A. Friederich, J. L. Guillaume, P. Keller, K. Knoch, R. Ahmad, P. Delagrange, M. Solimena, and R. Jockers. 2019. Detection of recombinant and endogenous mouse melatonin receptors by monoclonal antibodies targeting the C-terminal domain. J Pineal Res 66:e12540.
Hammoudi, N., M. Dhooge, R. Coriat, S. Leblanc, M. Barret, B. Bordacahar, F. Beuvon, F. Prat, F. Maksimovic, and S. Chaussade.Duodenal tumor risk in Lynch syndrome. Dig Liver Dis 2019 51:299-303.
Peranzoni, E., and E. Donnadieu.Improving efficacy of cancer immunotherapy through targeting of macrophages. Hum Vaccin Immunother 2019 15:189-192.
Haidar, M., M. Metheni, F. Batteux, and G. Langsley.TGF-beta2, catalase activity, H2O2 output and metastatic potential of diverse types of tumour. Free Radic Biol Med 2019134:282-287.
Karamitri, A., and R. Jockers. Melatonin in type 2 diabetes mellitus and obesity. Nat Rev Endocrinol 2019 15:105-125.
L'Hermitte, A., S. Pham, M. Cadoux, G. Couchy, S. Caruso, M. Anson, A. M. Crain-Denoyelle, S. Celton-Morizur, S. Yamagoe, J. Zucman-Rossi, C. Desdouets, and J. P. Couty.
Lect2 Controls Inflammatory Monocytes to Constrain the Growth and Progression of Hepatocellular Carcinoma. Hepatology 2019 69:160-178.
Senni, N., M. Savall, D. Cabrerizo Granados, M. C. Alves-Guerra, C. Sartor, I. Lagoutte, A. Gougelet, B. Terris, H. Gilgenkrantz, C. Perret, S. Colnot, and P. Bossard.
beta-catenin-activated hepatocellular carcinomas are addicted to fatty acids. Gut 2019 68:322-334.
Jean, C., F. Haghighirad, Y. Zhu, M. Chalbi, A. Ziyyat, E. Rubinstein, C. Gourier, P. Yip, J. P. Wolf, J. E. Lee, C. Boucheix, and V. Barraud-Lange.
JUNO, the receptor of sperm IZUMO1, is expressed by the human oocyte and is essential for human fertilisation. Hum Reprod 2019 34:118-126.
Bomsel, M., L. Lopalco, C. Uberti-Foppa, G. Siracusano, and Y. Ganor.
Short Communication: Decreased Plasma Calcitonin Gene-Related Peptide as a Novel Biomarker for HIV-1 Disease Progression. AIDS Res Hum Retroviruses 2019 35:52-55.
Mother smoking leads to methylation anomalies on 'smoke' genes in the offspring: Indelible traces of previous injuries. EBioMedicine 2018 38:11-12.
Exosomal microRNAs as a potential therapeutic strategy in hepatocellular carcinoma. World J Hepatol 2018 10:785-789.
Neveu, G., F. Dupuy, M. Ladli, D. Barbieri, B. Naissant, C. Richard, R. M. Martins, J. J. Lopez-Rubio, A. Bachmann, F. Verdier, and C. Lavazec.
Plasmodium falciparum gametocyte-infected erythrocytes do not adhere to human primary erythroblasts. Sci Rep 2018 8:17886.
Chatfield, S. M., N. Thieblemont, and V. Witko-Sarsat.
Expanding Neutrophil Horizons: New Concepts in Inflammation. J Innate Immun 2018 10:422-431.
Stoupa, A., F. Adam, D. Kariyawasam, C. Strassel, S. Gawade, G. Szinnai, A. Kauskot, D. Lasne, C. Janke, K. Natarajan, A. Schmitt, C. Bole-Feysot, P. Nitschke, J. Leger, F. Jabot-Hanin, F. Tores, A. Michel, A. Munnich, C. Besmond, R. Scharfmann, F. Lanza, D. Borgel, M. Polak, and A. Carre.
TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med 2018 10:e9569.
Garcia-Weber, D., A. S. Dangeard, J. Cornil, L. Thai, H. Rytter, A. Zamyatina, L. A. Mulard, and C. Arrieumerlou.
ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri. EMBO Rep 2018 19:e46543.
Gonzalez-Duque, S., M. E. Azoury, M. L. Colli, G. Afonso, J. V. Turatsinze, L. Nigi, A. I. Lalanne, G. Sebastiani, A. Carre, S. Pinto, S. Culina, N. Corcos, M. Bugliani, P. Marchetti, M. Armanet, M. Diedisheim, B. Kyewski, L. M. Steinmetz, S. Buus, S. You, D. Dubois-Laforgue, E. Larger, J. P. Beressi, G. Bruno, F. Dotta, R. Scharfmann, D. L. Eizirik, Y. Verdier, J. Vinh, and R. Mallone.
Conventional and Neo-antigenic Peptides Presented by beta Cells Are Targeted by Circulating Naive CD8+ T Cells in Type 1 Diabetic and Healthy Donors. Cell Metab 2018 28:946-960 e6.
Camus, M., F. Beuvon, M. Barret, E. Dalimier, H. El Bacha, S. Leblanc, R. Coriat, S. Chaussade, B. Terris, and F. Prat.
Full-field Optical Coherence Tomography: A New Imaging Modality for Rapid On-Site Evaluation of Resected Polyps During Colonoscopy. Gastroenterology 2018 155:1692-1694.
Mouasni, S., and L. Tourneur.
FADD at the Crossroads between Cancer and Inflammation.Trends Immunol 2018 39:1036-1053.
Dehghani, L., N. Mikail, N. Kramkimel, P. Soyer, R. Lebtahi, R. Mallone, and E. Larger.
Autoimmune pancreatitis after nivolumab anti-programmed death receptor-1 treatment. Eur J Cancer 2018 104:243-246.
Bellon, A., A. Wegener, A. R. Lescallette, M. Valente, Y. Sung-Kwon, R. Gardette, J. Matricon, P. Watts, F. Mouaffak, L. Vimeux, J. K. Yun, Y. I. Kawasawa, G. Clawson, E. Blandin, B. Chaumette, T. M. Jay, M. O. Krebs, V. Feuillet, and A. Hosmalin.
Transdifferentiation of human circulating monocytes into neuronal-like cells in 20 days and without reprograming. Frontiers Mol Neuroscience 2018 10.3389:00323.
Ramspott, J. P., F. Bekkat, L. Bod, M. Favier, B. Terris, A. Salomon, L. Djerroudi, K. S. Zaenker, Y. Richard, V. Molinier-Frenkel, F. Castellano, M. F. Avril, and A. Prevost-Blondel.
Emerging Role of IL-4-Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma. J Invest Dermatol 2018 138:2625-2634.
de Dieuleveult, M., and B. Miotto.
DNA Methylation and Chromatin: Role(s) of Methyl-CpG-Binding Protein ZBTB38. Epigenetics Insights 2018 11:1-5.
Petre, G., P. Lores, H. Sartelet, A. Truffot, B. Poreau, S. Brandeis, G. Martinez, V. Satre, R. Harbuz, P. F. Ray, F. Amblard, F. Devillard, G. Vieville, F. Berger, P. S. Jouk, D. Vaiman, A. Toure, C. Coutton, and M. Bidart.Genomic duplication in the 19q13.42 imprinted region identified as a new genetic cause of intrauterine growth restriction. Clin Genet 2018 94:575-580.
Javary, J., N. Allain-Courtois, N. Saucisse, P. Costet, C. Heraud, F. Benhamed, R. Pierre, C. Bure, N. Pallares-Lupon, M. Do Cruzeiro, C. Postic, D. Cota, P. Dubus, J. Rosenbaum, and S. Benhamouche-Trouillet.
Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling. Gut 2018 67:2192-2203.
Tiako Meyo, M., J. Alexandre, F. Goldwasser, and B. Blanchet.
Low-Dose Abiraterone Regimen: Drug Monitoring Might Be the Key. J Clin Oncol 2018 36:3061-62.
Plainvert, C., M. Longo, E. Seringe, B. Saintpierre, E. Sauvage, L. Ma, J. Beghain, N. Dmytruk, G. Collobert, E. Hernandez, C. Manuel, P. Astagneau, P. Glaser, F. Ariey, C. Poyart, and A. Fouet.
A clone of the emergent Streptococcus pyogenes emm89 clade responsible for a large outbreak in a post-surgery oncology unit in France. Med Microbiol Immunol 2018 207:287-96.
Benleulmi-Chaachoua, A., A. Hegron, M. Le Boulch, A. Karamitri, M. Wierzbicka, V. Wong, I. Stagljar, P. Delagrange, R. Ahmad, and R. Jockers.
Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure. Cell Mol Life Sci 2018 75:4357-4370.
Frantz, C., C. Auffray, J. Avouac, and Y. Allanore.
Regulatory T Cells in Systemic Sclerosis. Front Immunol 2018 9:2356.
Marchal, C., M. de Dieuleveult, C. Saint-Ruf, N. Guinot, L. Ferry, S. T. Olalla Saad, M. Lazarini, P. A. Defossez, and B. Miotto.
Depletion of ZBTB38 potentiates the effects of DNA demethylating agents in cancer cells via CDKN1C mRNA up-regulation. Oncogenesis 2018 7:82.
Wein, M. N., M. Foretz, D. E. Fisher, R. J. Xavier, and H. M. Kronenberg.
Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential. Trends Endocrinol Metab 2018 29:723-735.
Bourdon, M., P. Santulli, C. Maignien, K. Pocate-Cheriet, A. Alwohaibi, L. Marcellin, S. Blais, and C. Chapron.
The interval between oocyte retrieval and frozen-thawed blastocyst transfer does not affect the live birth rate and obstetrical outcomes. PLoS One 2018 13:e0206067.
Weckel, A., D. Ahamada, S. Bellais, C. Mehats, C. Plainvert, M. Longo, C. Poyart, and A. Fouet.
The N-terminal domain of the R28 protein promotes emm28 group A Streptococcus adhesion to host cells via direct binding to three integrins. J Biol Chem 2018 293:16006-16018.
Auriau, J., C. Roujeau, Z. Belaid Choucair, A. Oishi, C. Derviaux, T. Roux, E. Trinquet, O. Hermine, R. Jockers, and J. Dam.
Gain of affinity for VEGF165 binding within the VEGFR2/NRP1 cellular complex detected by an HTRF-based binding assay. Biochem Pharmacol 2018 158:45-59.
Chapelet, A., Y. Foucher, N. Gerard, C. Rousseau, O. Zambon, C. Bretonniere, J. P. Mira, B. Charreau, and C. Guitton.
An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU. Crit Care 2018 22:251.
Backer, S., L. Lokmane, C. Landragin, M. Deck, S. Garel, and E. Bloch-Gallego.
Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring. Development 2018 145:153692.
Moral-Sanz, J., S. A. Lewis, S. MacMillan, F. A. Ross, A. Thomson, B. Viollet, M. Foretz, C. Moran, D. G. Hardie, and A. M. Evans.
The LKB1-AMPK-alpha1 signaling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria. Sci Signal 2018 11:10.1126.
Kowalski, K., M. Dos Santos, P. Maire, M. A. Ciemerych, and E. Brzoska.
Induction of bone marrow-derived cells myogenic identity by their interactions with the satellite cell niche. Stem Cell Res Ther 2018 9:258.
Ferreux, L., M. Bourdon, A. Sallem, P. Santulli, V. Barraud-Lange, N. Le Foll, C. Maignien, C. Chapron, D. de Ziegler, J. P. Wolf, and K. Pocate-Cheriet.
Megrelis, L., E. El Ghoul, F. Moalli, M. Versapuech, S. Cassim, N. Ruef, J. V. Stein, M. Mangeney, and J. Delon.
Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration. Frontiers Immunol 2018 9:103389.
Foretz, M., P. C. Even, and B. Viollet.
AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo. Int J Mol Sci 2018 19:E2826.
Sallem, A., J. Shore, I. Ray-Coquard, L. Ferreux, M. Bourdon, C. Maignien, C. Patrat, J. P. Wolf, and K. Pocate-Cheriet.
Fertility preservation in women with cancer: a national study about French oncologists awareness, experience, and feelings. J Assist Reprod Genet 2018 35:1843-1850.
Douguet, L., L. Bod, L. Labarthe, R. Lengagne, M. Kato, I. Couillin, and A. Prevost-Blondel.
Inflammation drives nitric oxide synthase 2 expression by gammadelta T cells and affects the balance between melanoma and vitiligo associated melanoma. Oncoimmunology 2018 7:e1484979.
Hirose, M., P. Schilf, S. Rohde, Y. Gupta, T. Sancerni, M. C. Alves-Guerra, C. Sina, R. Jaster, B. Miroux, and S. M. Ibrahim.
The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice. Mitochondrion 2018 42:50-53.
Kavian, N., S. Mehlal, M. Jeljeli, N. E. B. Saidu, C. Nicco, O. Cerles, S. Chouzenoux, A. Cauvet, C. Camus, M. Ait-Djoudi, C. Chereau, S. Kerdine-Romer, Y. Allanore, and F. Batteux.
The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma. Front Immunol 2018 9:1896.
Boleto, G., C. Guignabert, S. Pezet, A. Cauvet, J. Sadoine, L. Tu, C. Nicco, C. Gobeaux, F. Batteux, Y. Allanore, and J. Avouac.
T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis. Arthritis Res Ther 2018 20:197.
Leblond, A., S. Pezet, A. P. Trouvin, M. Elhai, V. Gonzalez, Y. Allanore, and J. Avouac.
Linking systemic angiogenic markers to synovial vascularization in rheumatoid arthritis. PLoS One 2018 13:e0203607.
Blanchet, B., E. Carton, M. Alyamani, L. Golmard, O. Huillard, A. Thomas-Scheomann, M. Vidal, F. Goldwasser, N. Sharifi, and J. Alexandre.
A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients. Pharmacol Res 2018 136:56-61.
Karamitri, A., B. Plouffe, A. Bonnefond, M. Chen, J. Gallion, J. L. Guillaume, A. Hegron, M. Boissel, M. Canouil, C. Langenberg, N. J. Wareham, C. Le Gouill, V. Lukasheva, O. Lichtarge, P. Froguel, M. Bouvier, and R. Jockers.
Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling. Sci Signal 2018 11:aan6622.
Camus, M., B. Napoleon, A. Vienne, M. Le Rhun, S. Leblanc, M. Barret, S. Chaussade, F. Robin, N. Kaddour, and F. Prat.
Efficacy and safety of endobiliary radiofrequency ablation for the eradication of residual neoplasia after endoscopic papillectomy: a multicenter prospective study. Gastrointest Endosc 2018 88:511-518.
Besancon, A., Z. Demir, T. Goncalves, F. Valette, E. Panafieu, L. Chatenoud, and S. You.
Differential Impact of T-bet and IFNgamma on Pancreatic Islet Allograft Rejection. Transplantation 2018 102:1496-1504.
Haouzi, P., M. Gueguinou, T. Sonobe, A. Judenherc-Haouzi, N. Tubbs, M. Trebak, J. Cheung, and F. Bouillaud.
Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication. Clin Toxicol (Phila) 2018 56:828-840.
Chougui, G., S. Munir-Matloob, R. Matkovic, M. M. Martin, M. Morel, H. Lahouassa, M. Leduc, B. C. Ramirez, L. Etienne, and F. Margottin-Goguet.
Luce, S., S. Guinoiseau, A. Gadault, F. Letourneur, B. Blondeau, P. Nitschke, E. Pasmant, M. Vidaud, F. Lemonnier, and C. Boitard.
Humanized Mouse Model to Study Type 1 Diabetes. Diabetes 2018 67:1816-1829.
Ramond, C., B. S. Beydag-Tasoz, A. Azad, M. van de Bunt, M. B. K. Petersen, N. L. Beer, N. Glaser, C. Berthault, A. L. Gloyn, M. Hansson, M. I. McCarthy, C. Honore, A. Grapin-Botton, and R. Scharfmann.
Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling. Development 2018 145:165480.
Cecon, E., A. Oishi, and R. Jockers.
Melatonin receptors: molecular pharmacology and signalling in the context of system bias. Br J Pharmacol 2018 175:3263-80.
Clement, N., N. Renault, J. L. Guillaume, E. Cecon, A. S. Journe, X. Laurent, K. Tadagaki, F. Coge, A. Gohier, P. Delagrange, P. Chavatte, and R. Jockers.
Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50. Br J Pharmacol 2018 175:3281-97.
Huang, H. Y., A. Rivas-Caicedo, F. Renevey, H. Cannelle, E. Peranzoni, L. Scarpellino, D. L. Hardie, A. Pommier, K. Schaeuble, S. Favre, T. K. Vogt, F. Arenzana-Seisdedos, P. Schneider, C. D. Buckley, E. Donnadieu, and S. A. Luther.
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis. Proc Natl Acad Sci 2018 U S A 115:E6826-E6835.
Rouxel, O., and A. Lehuen.
Mucosal-associated invariant T cells in autoimmune and immune-mediated diseases. Immunol Cell Biol 2018 96:618-629.
Terrier, B., C. Pagnoux, E. Perrodeau, A. Karras, C. Khouatra, O. Aumaitre, P. Cohen, O. Decaux, H. Desmurs-Clavel, F. Maurier, P. Gobert, T. Quemeneur, C. Blanchard-Delaunay, B. Bonnotte, P. L. Carron, E. Daugas, M. Ducret, P. Godmer, M. Hamidou, O. Lidove, N. Limal, X. Puechal, L. Mouthon, P. Ravaud, L. Guillevin, and G. French Vasculitis Study.
Long-term efficacy of remission-maintenance regimens for ANCA-associated vasculitides. Ann Rheum Dis 2018 77:1150-1156.
Stoupa, A., R. Chaabane, M. Gueriouz, C. Raynaud-Ravni, P. Nitschke, C. Bole-Feysot, M. Mnif, L. Ammar Keskes, M. Hachicha, N. Belguith, M. Polak, and A. Carre.
Thyroid Hypoplasia in Congenital Hypothyroidism Associated with Thyroid Peroxidase Mutations. Thyroid 2018 28:941-944.
Agosta, C., J. Laugier, L. Guyon, J. Denis, J. Bertherat, R. Libe, B. Boisson, N. Sturm, J. J. Feige, O. Chabre, and N. Cherradi.
MiR-483-5p and miR-139-5p promote aggressiveness by targeting N-myc downstream-regulated gene family members in adrenocortical cancer. Int J Cancer 2018 143:944-957.
Hoyles, L., J. M. Fernandez-Real, M. Federici, M. Serino, J. Abbott, J. Charpentier, C. Heymes, J. L. Luque, E. Anthony, R. H. Barton, J. Chilloux, A. Myridakis, L. Martinez-Gili, J. M. Moreno-Navarrete, F. Benhamed, V. Azalbert, V. Blasco-Baque, J. Puig, G. Xifra, W. Ricart, C. Tomlinson, M. Woodbridge, M. Cardellini, F. Davato, I. Cardolini, O. Porzio, P. Gentileschi, F. Lopez, F. Foufelle, S. A. Butcher, E. Holmes, J. K. Nicholson, C. Postic, R. Burcelin, and M. E. Dumas.
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women. Nat Med 2018 24:1070-1080.
Besancon, A., T. Goncalves, F. Valette, C. Mary, B. Vanhove, L. Chatenoud, and S. You.
A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice. Diabetologia 2018 61:1811-1816.
Boudaba, N., A. Marion, C. Huet, R. Pierre, B. Viollet, and M. Foretz.
AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development. EBioMedicine 2018 28:194-209.
Bourdoulous, S., and E. Lemichez.
Decoding glycan recognition by bacterial toxins. Nat Microbiol 2018 3:124-126.
Brusson, M., M. De Grandis, S. Cochet, S. Bigot, M. Marin, M. Leduc, F. Guillonneau, P. Mayeux, T. Peyrard, C. Chomienne, C. Le Van Kim, B. Cassinat, J. J. Kiladjian, and W. El Nemer.
Impact of hydroxycarbamide and interferon-alpha on red cell adhesion and membrane protein expression in polycythemia vera. Haematologica 2018 103:972-981.
Hegde, P., E. Weiss, V. Paradis, J. Wan, M. Mabire, S. Sukriti, P. E. Rautou, M. Albuquerque, O. Picq, A. C. Gupta, G. Ferrere, H. Gilgenkrantz, B. Kiaf, A. Toubal, L. Beaudoin, P. Letteron, R. Moreau, A. Lehuen, and S. Lotersztajn.
Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver. Nat Commun 2018 9:2146.
Deveau, P., L. Colmet Daage, D. Oldridge, V. Bernard, A. Bellini, M. Chicard, N. Clement, E. Lapouble, V. Combaret, A. Boland, V. Meyer, J. F. Deleuze, I. Janoueix-Lerosey, E. Barillot, O. Delattre, J. M. Maris, G. Schleiermacher, and V. Boeva.
QuantumClone: clonal assessment of functional mutations in cancer based on a genotype-aware method for clonal reconstruction.Bioinformatics 2018 34:1808-1816.
Hadjadj, J., G. Canaud, T. Mirault, M. Samson, P. Bruneval, A. Regent, C. Goulvestre, V. Witko-Sarsat, N. Costedoat-Chalumeau, L. Guillevin, L. Mouthon, B. Terrier, and G. French Vasculitis Study.
mTOR pathway is activated in endothelial cells from patients with Takayasu arteritis and is modulated by serum immunoglobulin G. Rheumatology (Oxford) 2018 57:1011-1020.
Bricambert, J., M. C. Alves-Guerra, P. Esteves, C. Prip-Buus, J. Bertrand-Michel, H. Guillou, C. J. Chang, M. N. Vander Wal, F. Canonne-Hergaux, P. Mathurin, V. Raverdy, F. Pattou, J. Girard, C. Postic, and R. Dentin.
The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 2018 9:2092.
Igonet, S., C. Raingeval, E. Cecon, M. Pucic-Bakovic, G. Lauc, O. Cala, M. Baranowski, J. Perez, R. Jockers, I. Krimm, and A. Jawhari.
Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor. Sci Rep 2018 8:8142.
Abitbol, S., R. Dahmani, C. Coulouarn, B. Ragazzon, B. Mlecnik, N. Senni, M. Savall, P. Bossard, P. Sohier, V. Drouet, E. Tournier, F. Dumont, R. Sanson, J. Calderaro, J. Zucman-Rossi, M. Vasseur-Cognet, P. A. Just, B. Terris, C. Perret, and H. Gilgenkrantz.
AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of beta-catenin activation. J Hepatol 2018 68:1203-1213.
Miotto, B., C. Marchal, G. Adelmant, N. Guinot, P. Xie, J. A. Marto, L. Zhang, and P. A. Defossez.
Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. Nucleic Acids Res 2018 46:4392-4404.
Ohradanova-Repic, A., C. Machacek, C. Charvet, F. Lager, D. Le Roux, R. Platzer, V. Leksa, G. Mitulovic, T. R. Burkard, G. J. Zlabinger, M. B. Fischer, V. Feuillet, G. Renault, S. Bluml, M. Benko, M. Suchanek, J. B. Huppa, T. Matsuyama, A. Cavaco-Paulo, G. Bismuth, and H. Stockinger.
Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances. Front Immunol 2018 9:852.
Olivier, S., M. Foretz, and B. Viollet.
Promise and challenges for direct small molecule AMPK activators. Biochem Pharmacol 2018 153:147-158.
Tacnet-Delorme, P., J. Gabillet, S. Chatfield, N. Thieblemont, P. Frachet, and V. Witko-Sarsat.
Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells. Front Immunol 2018 9:818.
Garcin, L., D. Kariyawasam, K. Busiah, A. L. Fauret-Amsellem, F. Le Bourgeois, L. Vaivre-Douret, H. Cave, M. Polak, and J. Beltrand.
Successful off-label sulfonylurea treatment of neonatal diabetes mellitus due to chromosome 6 abnormalities. Pediatr Diabetes 2018 19:663-669.
Ung, D. C., G. Iacono, H. Meziane, E. Blanchard, M. A. Papon, M. Selten, J. R. van Rhijn, R. Montjean, J. Rucci, S. Martin, A. Fleet, M. C. Birling, S. Marouillat, R. Roepman, M. Selloum, A. Lux, R. A. Thepault, P. Hamel, K. Mittal, J. B. Vincent, O. Dorseuil, H. G. Stunnenberg, P. Billuart, N. Nadif Kasri, Y. Herault, and F. Laumonnier.
Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse. Mol Psychiatry 2018 23:1356-1367.
Real, F., A. Sennepin, Y. Ganor, A. Schmitt, and M. Bomsel.
Live Imaging of HIV-1 Transfer across T Cell Virological Synapse to Epithelial Cells that Promotes Stromal Macrophage Infection. Cell Rep 2018 23:1794-1805.
Dejarnac, O., M. L. Hafirassou, M. Chazal, M. Versapuech, J. Gaillard, M. Perera-Lecoin, C. Umana-Diaz, L. Bonnet-Madin, X. Carnec, J. Y. Tinevez, C. Delaugerre, O. Schwartz, P. Roingeard, N. Jouvenet, C. Berlioz-Torrent, L. Meertens, and A. Amara.
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