Source: https://people.epfl.ch/cristina.cudalbu
Timestamp: 2019-04-24 04:19:13+00:00

Document:
Laboratory for Functional and Metabolic Imaging (LIFMET), Lausanne, Switzerland.
University Lyon 1, RMN Laboratory MIB, UMR CNRS 5012, ESCPE, Villeurbanne, France.
-In vivo macromolecules contribution in 1H MRS spectra: measurement and quantification at high magnetic field invited by Prof. Dr. sc. nat. Roland Kreis, University Bern, AMSM, DRNN/DKF, October, 2013.
-Chronic Hepatic Encephalopathy:how MRS and MRI can help in elucidating the molecular mechanisms  invited by Prof. Dr. Zenon Star?uk, Institute of Scientific Instruments Brno, Brno, Czech Republic, 2013.
-MRS of Rodents at Ultra-High Fields within MR Spectroscopy & Spectroscopic Imagingsunrise course, held at the ISMRM 2012 Meeting in Melbourne, Australia, 5-11 May, 2012.
- Metabolite quantification within Potentials and challenges of high-field MRS sunrise course, held at the ISMRM-ESMRMB 2009 Meeting in Stockholm, Sweden, 1-7 May, 2010.
- Continuous formation Breakfast & Science event at CIBM: MRS of rodents: recent insights Febr 2012.
- Image à résonance magnétique nucléaire et son application en expérimentation animale  held during « Cours dIntroduction à lExpérimentation Animale (Module 1) » 19 March 2010, Lausanne.
- Regular teaching during the Doctoral course Advanced biomedical imaging methods and instrumentation, EPFL, Lausanne (2009-2013).
1.	V.Rackayova, M.Loup, H.Henry, V.A.McLin, C.Cudalbu, O.Braissant. “Secondary brain creatine deficiency and neurological impairment in BDL rats, an in vivo model of chronic cholestatic liver disease”.
9.	Veronika Rackayová, Cristina Cudalbu, Lijing Xin, Nicolas Kunz, Jana Starcukova, Zenon Starcuk and Rolf Gruetter (2015). Influence of different TE on reliability of brain metabolites quantification in high field 1H MRS.
12.	Veronika Rackayová, Olivier Braissant, Corina Berset, Cristina Cudalbu and Valérie A. McLin. “In vivo Longitudinal Study Of Brain Metabolism And Edema In Chronic Hepatic Encephalopathy In Developing And Adult Rat Brain”.
19.	C.Cudalbu, O.Braissant, A.Jayaswal, R.Gruetter, V.A.McLin. “In vivo brain energy metabolism in a rat model of chronic hepatic encephalopathy using 31P MRS”.
20.	C.Cudalbu, O.Braissant, V.A.McLin. “Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study”.
21.	C.Cudalbu, V.A.McLin, O.Braissant “Brain metabolism and edema in chronic hepatic encephalopathy: A longitudinal in vivo study”.
22.	B.Lanz, C.Cudalbu, V.A.McLin, O.Braissant, R.Gruetter “Effects of chronic hepatic encephalopathy on brain energy metabolism, studied by in vivo 13C MRS in rats”.
23.	C. Cudalbu, O. Braissant, M Lepore, R. Gruetter and V.A. McLin” Brain osmolytes and brain edema in a rat model of chronic liver failure: in vivo longitudinal 1H Spectroscopic imaging and Diffusion tensor imaging studies at 9.4T”.
24.	V.A. McLin, O. Braissant, Y. van de Looij, N. Kunz, R. Gruetter and C. Cudalbu. ”ASSESSMENT OF CEREBRAL OSMOTIC REGULATION IN A RAT MODEL OF BILIARY CIRRHOSIS USING MR SPECTROSCOPY”.
30.	Cristina Cudalbu, Nicolas Kunz, Bernard Lanz, Yohan Van de Looij, Vladimir Mlynárik, and Rolf Gruetter "Imaging the in vivo effect of hyperammonemia in the rat brain: a Spectroscopic Imaging and Diffusion Tensor Imaging study".
31.	C. Cudalbu, B. Lanz, J. M. Duarte, N. Kunz, and R. Gruetter "Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES".
32.	C. Cudalbu, A. Comment, T. Cheng, M. Mishkovsky, and R. Gruetter "In vivo localized 15N MRS detection of hyperpolarized 15N labeled choline in the rat brain".
33.	C. Cudalbu, M. Craveiro, V. Mlynárik, J. Bremer, A. Aguzzi, and R. Gruetter "In vivo longitudinal 1H MRS study of transgenic mouse models of prion disease in the hippocampus and cerebellum at 14.1T".
34.	M. Craveiro, L. Quignodon, C. Berthet, M. Hall, C. Cudalbu, L. Hirt, B. Desvergne, and R. Gruetter "Early post-ischemic neuroprotective mechanisms: a MR spectroscopic imaging study on PPARβ-deficient mice".
M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al. : Methodological consensus on clinical proton MRS of the brain: Review and recommendations; Magnetic Resonance in Medicine. 2019. DOI : 10.1002/mrm.27742.
M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M.-F. Hamou et al. : In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells; International Journal of Cancer. 2018. DOI : 10.1002/ijc.31299.
M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al. : In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018. DOI : 10.1177/0271678X17734101.
C. Cudalbu; A. J. L. Cooper : Editorial for the special issue on introduction to in vivo Magnetic Resonance Spectroscopy (MRS): A method to non-invasively study metabolism; Analytical Biochemistry. 2017. DOI : 10.1016/j.ab.2017.05.014.
B. Lanz; V. Rackayova; O. Braissant; C. Cudalbu : MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models; Analytical biochemistry. 2017. DOI : 10.1016/j.ab.2016.11.021.
V. Rackayova; C. Cudalbu; P. J. W. Pouwels; O. Braissant : Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies; Analytical biochemistry. 2017. DOI : 10.1016/j.ab.2016.11.007.
C. Bémeur; C. Cudalbu; G. Dam; A. S. Thrane; A. J. L. Cooper et al. : Brain edema: a valid endpoint for measuring hepatic encephalopathy?; Metabolic brain disease. 2016. DOI : 10.1007/s11011-016-9843-9.
V. Rackayova; O. Braissant; V. A. McLin; C. Berset; B. Lanz et al. : (1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism; Metabolic brain disease. 2016. DOI : 10.1007/s11011-015-9715-8.
C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al. : In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T; Neurochemical research. 2015. DOI : 10.1007/s11064-015-1643-9.
M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter : Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T; NMR in Biomedicine. 2014. DOI : 10.1002/nbm.3168.
G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al. : Clinical Proton MR Spectroscopy in Central Nervous System Disorders; Radiology. 2014. DOI : 10.1148/radiol.13130531.
M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu : In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T; Journal of Neurochemistry. 2014. DOI : 10.1111/jnc.12673.
C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A.-L. Rougemont et al. : The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts; PLoS ONE. 2013. DOI : 10.1371/journal.pone.0069782.
C. Cudalbu : In vivo studies of brain metabolism in animal models of Hepatic Encephalopathy using (1)H Magnetic Resonance Spectroscopy; Metabolic brain disease. 2013. DOI : 10.1007/s11011-012-9368-9.
O. Braissant; V. A. McLin; C. Cudalbu : Ammonia toxicity to the brain; Journal of inherited metabolic disease. 2013. DOI : 10.1007/s10545-012-9546-2.
L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter : Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain; Magma (New York, N.Y.). 2013. DOI : 10.1007/s10334-013-0378-3.
B. Schaller; L. Xin; C. Cudalbu; R. Gruetter : Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T; NMR in biomedicine. 2013. DOI : 10.1002/nbm.2896.
B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al. : Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES; Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2013. DOI : 10.1002/mrm.24406.
C. Cudalbu; V. Mlynárik; R. Gruetter : Handling macromolecule signals in the quantification of the neurochemical profile; Journal of Alzheimer's disease : JAD. 2012. DOI : 10.3233/JAD-2012-120100.
V. Mlynárik; M. Cacquevel; L. Sun-Reimer; S. Janssens; C. Cudalbu et al. : Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer's disease; Journal of Alzheimer's disease : JAD. 2012. DOI : 10.3233/JAD-2012-112072.
C. R. Cudalbu; B. Lanz; J. M. N. Duarte; F. D. Morgenthaler; Y. Pilloud et al. : Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy; Journal Of Cerebral Blood Flow And Metabolism. 2012. DOI : 10.1038/jcbfm.2011.173.
V. Mlynarik; C. R. Cudalbu; V. Clement; D. Marino; I. Radovanovic et al. : In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla; Nmr In Biomedicine. 2012. DOI : 10.1002/nbm.1763.
N. Just; C. R. Cudalbu; H. Lei; R. Gruetter : Effect of manganese chloride on the neurochemical profile of the rat hypothalamus; Journal of Cerebral Blood Flow and Metabolism. 2011. DOI : 10.1038/jcbfm.2011.92.
V. Clement; D. Marino; C. R. Cudalbu; M.-F. Hamou; V. Mlynarik et al. : Marker-independent identification of glioma-initiating cells; Nature Methods. 2010. DOI : 10.1038/NMETH.1430.
N. Kunz; C. R. Cudalbu; V. Mlynarik; P. S. Hueppi; S. V. Sizonenko et al. : Diffusion-Weighted Spectroscopy: A Novel Approach to Determine Macromolecule Resonances in Short-Echo Time H-1-MRS; Magnetic Resonance In Medicine. 2010. DOI : 10.1002/mrm.22490.
C. R. Cudalbu; A. Comment; F. Kurdzesau; R. van Heeswijk; K. Uffmann et al. : Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats; Physical Chemistry Chemical Physics. 2010. DOI : 10.1039/c002309b.
R. van Heeswijk; K. Uffmann; A. Comment; F. Kurdzesau; C. Perazzolo et al. : Hyperpolarized Lithium-6 as a Sensor of Nanomolar Contrast Agents; Magnetic Resonance In Medicine. 2009. DOI : 10.1002/mrm.21952.
C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter : Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum; Measurement Science & Technology. 2009. DOI : 10.1088/0957-0233/20/10/104034.
C. R. Cudalbu; V. Mlynarik; L. Xin; R. Gruetter : Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla; Magnetic Resonance In Medicine. 2009. DOI : 10.1002/mrm.22022.
V. Mlynarik; C. R. Cudalbu; L. Xin; R. Gruetter : H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile; Journal Of Magnetic Resonance. 2008. DOI : 10.1016/j.jmr.2008.06.019.
C. Cudalbu, V. Mlynárik, L. Xin, R. Gruetter. Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE 1H MRS spectra. IEEE International Workshop on Imaging Systems and Techniques  IST 2008, Chania, Greece, September 1012, 2008, pp 311-314 C. Cudalbu, A. Bucur, D. Graveron-Demilly, O. Beuf, S. Cavassila. Comparison of two strategies of background-accommodation: Influence on the metabolite concentration estimation from in vivo Magnetic Resonance Spectroscopy data, IEEE Engineering in Medicine and Biology Society, IEEE EMB, 2007, pp 2077-2080. C. Cudalbu, S. Cavassila, H. Rabeson, D. van Ormondt, D. Graveron-Demilly, Localized Proton Magnetic Resonance Spectroscopy at 7 Tesla in the Rat Brain: Metabolite Concentration Estimates Using QUEST and Two Approaches to Accommodate the Background, IEEE Benelux, Proc. ProRISC, 2006, pp 136-140. H. Rabeson, F. Fauvelle, H. Ratiney, C. Cudalbu, S. Cavassila, D. van Ormondt, D. Graveron-Demilly, Quantitation with QUEST of ER-Filtered HRMAS-NMR Signals, IEEE Benelux, Proc. ProRISC, 2006, pp 171-175. H. Rabeson, H. Ratiney, C. Cudalbu, S. Cavassila, E. Capobianco, R. de Beer, D. van Ormondt, D. Graveron-Demilly Signal Disentanglement in In Vivo MR Spectroscopy: By Semi-Parametric Processing or by Measurement?, IEEE Benelux, Proc. ProRISC, 2006, pp 176-183. C. Cudalbu, S. Cavassila, H. Ratiney, O. Beuf, D. van Ormondt, D. Graveron-Demilly, Metabolite Concentration Estimates in the Rat Brain by Magnetic Resonance Spectroscopy Using QUEST and Two Approaches to Invoke Prior Knowledge, Proc. ProRISC, IEEE Benelux, 2005, pp 609-614. H. Ratiney, E. Capobianco, M. Sdika, H. Rabeson, C. Cudalbu, S. Cavassila, R. de Beer, D. van Ormondt, D. Graveron-Demilly, Semi-Parametric Estimation in In Vivo MR Spectroscopy, Proc. ProRISC, IEEE Benelux, 2005, pp 658-667. C. Cudalbu, S. Cavassila, H. Ratiney, O. Beuf, A. Briguet, D. Graveron-Demilly, Metabolite concentrations of healthy mouse brain By Magnetic Resonance Spectroscopy at 7 Tesla, 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE EMB, 2005, 1140. B. Tchong Len, H. Ratiney, C. Cudalbu, B. Fenet, A.R. Allouche, M. Aubert-Frécon, D. van Ormondt, D. Graveron-Demilly, Quantitation of Edited GABA Signals in Magnetic Resonance Spectroscopy, Proc. ProRISC, IEEE Benelux, 2004 , pp. 311-316.
2014: PI for the Industrial grant VSL Pharmaceuticals Inc.

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