Source: http://www.mauricewilkinscentre.org/sub-pages/publications/scientific-publications.aspx?year=2012
Timestamp: 2019-04-21 16:50:41+00:00

Document:
Every year Maurice Wilkins Centre investigators produce a large number of peer-reviewed scientific papers and reviews published in international journals. Research directly supported by the Maurice Wilkins Centre generated the following scientific papers.
Ancelet, L., Rich, F. J., Delahunt, B., & Kirman, J. R. Dissecting memory T cell responses to TB: Concerns using adoptive transfer into immunodeficient mice. Tuberculosis (2012) 92(5): 422-433.
Araki, H., Knapp, C., Tsai, P., & Print, C. GeneSetDB: A comprehensive metadatabase, statistical and visualisation framework for gene set analysis. FEBS Open Bio (2012) 2: 76-82.
Bailey, R. J., Walker, C. S., Ferner, A. H., Loomes, K. M., Prijic, G., Halim, A., Whiting, L., Phillips, A. R. J., & Hay, D. L. Pharmacological characterization of rat amylin receptors: Implications for the identification of amylin receptor subtypes. British Journal of Pharmacology (2012) 166(1): 151-167.
Baker, H. M., & Baker, E. N. A structural perspective on lactoferrin function. Biochemistry and Cell Biology (2012) 90(3): 320-328.
Bashiri, G., Perkowski, E. F., Turner, A. P., Feltcher, M. E., Braunstein, M., & Baker, E. N. Tat-dependent translocation of an F420-binding protein of Mycobacterium tuberculosis. PLoS ONE (2012) 7(10): e45003.
Steger, J., Koch, C. E., Olkrug, R., Schwartz, M. W., Shepherd, P. R., Grattan, D.
Barwell, J., Gingell, J. J., Watkins, H. A., Archbold, J. K., Poyner, D. R., & Hay, D. L. Calcitonin and calcitonin receptor-like receptors: Common themes with family B GPCRs? British Journal of Pharmacology (2012) 166(1): 51-65.
Blumenstein, M., McCowan, L. M. E., Wu, S., Cooper, G. J. S., & North, R. A. Plasma clusterin increased prior to small for gestational age (SGA) associated with preeclampsia and decreased prior to SGA in normotensive pregnancies. Reproductive Sciences (2012) 19(6): 650-657.
Berney, M., Weimar, M. R., Heikal, A., & Cook, G. M. Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia. Molecular Microbiology (2012) 84(4): 664-681.
Bogle, G., & Dunbar, P. R. On-lattice simulation of T cell motility, chemotaxis, and trafficking in the lymph node paracortex. PLoS ONE (2012) 7(9): e45258.
Brimble, M. A., Haym, I., Sperry, J., & Furkert, D. P. Synthesis of the tetracyclic core of berkelic acid using gold(I)-catalyzed hydroarylation and oxidative radical cyclizations. Organic Letters (2012) 14(23): 5820-5823.
Broadbent, E., Kahokehr, A., Booth, R. J., Thomas, J., Windsor, J. A., Buchanan, C. M., Wheeler, B. R. L., Sammour, T., & Hill, A. G. A brief relaxation intervention reduces stress and improves surgical wound healing response: A randomised trial. Brain, Behavior, and Immunity (2012) 26(2): 212-217.
Buchanan, C. M., Shih, J. H., Astin, J. W., Rewcastle, G. W., Flanagan, J. U., Crosier, P. S., & Shepherd, P. R. DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular. Clinical Science (2012) 122(10): 449-457.
Bunker, R. D., Dickson, J. M. J., Caradoc-Davies, T. T., Loomes, K. M., & Baker, E. N. Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human D-xylulokinase. Acta Crystallographica Section F: Structural Biology and Crystallization Communications (2012) 68(10): 1259-1262.
Busby, J. N., Landsberg, M. J., Simpson, R. M., Jones, S. A., Hankamer, B., Hurst, M. R. H., & Lott, J. S. Structural analysis of Chi1 chitinase from Yen-Tc: The multisubunit insecticidal ABC toxin complex of Yersinia entomophaga. Journal of Molecular Biology (2012) 415(2): 359-371.
Caldon, C. E., Sergio, C. M., Kang, J., Muthukaruppan, A., Boersma, M. N., Stone, A., Barraclough, J., Lee, C. S., Black, M. A., Miller, L. D., Gee, J. M., Nicholson, R. I., Sutherland, R. L., Print, C. G., & Musgrove, E. A. Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells. Molecular Cancer Therapeutics (2012) 11(7): 1488-1499.
Chi, G., Manos-Turvey, A., O’Connor, P. D., Johnston, J. M., Evans, G. L., Baker, E. N., Payne, R. J., Lott, J. S., & Bulloch, E. M. M. Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis. Biochemistry (2012) 51(24): 4868-4879.
Chiu, E., Coulibaly, F., & Metcalf, P. Insect virus polyhedra, infectious protein crystals that contain virus particles. Current Opinion in Structural Biology (2012) 22(2): 234- 240.
Chorley, D. F., Chen, J. L. Y., Furkert, D. P., Sperry, J., & Brimble, M. A. Total synthesis of danshenspiroketallactone. Synlett (2012) 1: 128-130.
Clark, G. R., Pytel, P. D., & Squire, C. J. The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages. Nucleic Acids Research (2012) 40(12): 5731-5738.
Cook, G. M., & Heikal, A. Bridging the gap between a TB drug and its target. Science Translational Medicine (2012) 4(150) fs33.
Cooper, G. J. S. Selective divalent copper chelation for the treatment of diabetes mellitus. Current Medicinal Chemistry (2012) 19(17): 2828-2860.
Coulibaly, F., Lassalle, E., Baker, H. M., & Baker, E. N. Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis. Acta Crystallographica Section D: Biological Crystallography (2012) 68(5): 553-563.
Dangerfield, E. M., Cheng, J. M. H., Knight, D. A., Weinkove, R., Dunbar, P. R., Hermans, I. F., Timmer, M. S. M., & Stocker, B. L. Species-specific activity of glycolipid ligands for invariant NKT cells. ChemBioChem (2012) 13(9): 1349-1356.
Dbouk, H. A., Vadas, O., Shymanets, A., Burke, J. E., Salamon, R. S., Khalil, B. D., Barrett, M. O., Waldo, G. L., Surve, C., Hsueh, C., Perisic, O., Harteneck, C., Shepherd, P. R., Harden, T. K., Smrcka, A. V., Taussig, R., Bresnick, A. R., Nurnberg, B., Williams, R. L., & Backer, J. M. G protein-coupled receptor-mediated activation of p110 beta by G beta gamma is required for cellular transformation and invasiveness. Science Signaling (2012) 5(253): ra89.
De Bono, B., & Hunter, P. Integrating knowledge representation and quantitative modelling in physiology. Biotechnology Journal (2012) 7(8): 958-972.
Dimitrov, I., Furkert, D. P., Fraser, J. D., Radcliff, F. J., Finch, O., & Brimble, M. A. Synthesis and anti-Helicobacter pylori activity of analogues of spirolaxine methyl ether. MedChemComm (2012) 3(8): 944-949.
Donges, C. E., Burd, N. A., Duffield, R., Smith, G. C., West, D. W. D., Short, M. J., Mackenzie, R., Plank, L. D., Shepherd, P. R., Phillips, S. M., & Edge, J. A. Concurrent resistance and aerobic exercise stimulates both myofibrillar and mitochondrial protein synthesis in sedentary middle-aged men. Journal of Applied Physiology (2012) 112(12): 1992-2001.
Enomoto, N., Hyde, E., Ma, J. Z. I., Yang, J., Forbes-Blom, E., Delahunt, B., Le Gros, G., & Ronchese, F. Allergen-specific CTL require perforin expression to suppress allergic airway inflammation. Journal of Immunology (2012) 188(4): 1734-1741.
Evans, C. W., Hellman, L., Middleditch, M., Wojnar, J. M., Brimble, M. A., & Devries, A. L. Synthesis and recycling of antifreeze glycoproteins in polar fishes. Antarctic Science (2012) 24(3): 259-268.
Evans, C. W., Williams, D. E., Vacchi, M., Brimble, M. A., & DeVries, A. L. Metabolic and behavioural adaptations during early development of the Antarctic silverfish, Pleuragramma antarcticum. Polar Biology (2012) 35(6): 891-898.
Evans, G. E., Martinez-Conejero, J. A., Phillipson, G. T. M., Simon, C., Mcnoe, L. A., Sykes, P. H., Horcajadas, J. A., Lam, E. Y. N., Print, C. G., Sin, I. L., & Evans, J. J. Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertility and Sterility (2012) 97(6): 1365-1373.
Fernandez, J. W., Haque, M. Z. U., Hunter, P. J., & Mithraratne, K. Mechanics of the foot Part 1: A continuum framework for evaluating soft tissue stiffening in the pathologic foot. International Journal for Numerical Methods in Biomedical Engineering (2012) 28(10): 1056-1070.
Fernandez, J. W., Shim, V. B., & Hunter, P. J. Integrating degenerative mechanisms in bone and cartilage: A multiscale approach. 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS) (2012): 6616-6619.
Flanagan, J. U., Yosaatmadja, Y., Teague, R. M., Chai, M. Z. L., Turnbull, A. P., & Squire, C. J. Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PLoS ONE (2012) 7(8): e43965.
Forbes-Blom, E., Camberis, M., Prout, M., Tang, S. C., & Le Gros, G. Staphylococcalderived superantigen enhances peanut induced Th2 responses in the skin. Clinical and Experimental Allergy (2012) 42(2): 305-314.
Ge, Q., Moir, L. M., Trian, T., Niimi, K., Poniris, M., Shepherd, P. R., Black, J. L., Oliver, B. G., & Burgess, J. K. The phosphoinositide 3'-kinase p110delta modulates contractile protein production and IL-6 release in human airway smooth muscle. Journal of Cellular Physiology (2012) 227(8): 3044-3052.
Geng, H., Chen, J. Y., Furkert, D., Jiang, S., & Brimble, M. A. A convergent synthesis of the 2-formylpyrrole spiroketal natural product acortatarin A. Synlett (2012) 23(6): 855-858.
Goodall, K. J., Brimble, M. A., & Barker, D. A tandem Diels-Alder/Mannich approach to the synthesis of AE and ABE ring analogues of Delphinium alkaloids. Tetrahedron (2012) 68(29): 5759-5778.
Han, J. C., Taberner, A. J., Tran, K., Goo, S., Nickerson, D. P., Nash, M. P., Nielsen, P. M. F., Crampin, E. J., & Loiselle, D. S. Comparison of the Gibbs and Suga formulations of cardiac energetics: The demise of “isoefficiency”. Journal of Applied Physiology (2012) 113(7): 996-1003.
Han, J. C., Taberner, A. J., Tran, K., Nickerson, D. P., Nash, M. P., Nielsen, P. M. F., Crampin, E. J., & Loiselle, D. S. Relating components of pressure-volume area in Suga’s formulation of cardiac energetics to components of the stress-time integral. Journal of Applied Physiology (2012) 113(7): 988-995.
Han, J. C., Tran, K., Taberner, A. J., Nickerson, D. P., Kirton, R. S., Nielsen, P. M. F., Ward, M. L., Nash, M. P., Crampin, E. J., & Loiselle, D. S. Myocardial twitch duration and the dependence of oxygen consumption on pressure-volume area: Experiments and modelling. Journal of Physiology (2012) 590(18): 4603-4622.
Harris, P. W., Lee, D. J., & Brimble, M. A. A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography. Journal of Peptide Science (2012) 18(9): 549-555.
Harris, P. W. R., & Brimble, M. A. The chemical synthesis of the collagenous domain of the hormone adiponectin. International Journal of Peptide Research and Therapeutics (2012) 18(1): 63-70.
Harrison, A. N., Reichau, S., & Parker, E. J. Synthesis and evaluation of tetrahedral intermediate mimic inhibitors of 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Bioorganic and Medicinal Chemistry Letters (2012) 22(2): 907-911.
Haym, I., & Brimble, M. A. The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis. Organic & Biomolecular Chemistry (2012) 10(38): 7649- 7665.
Heapy, A. M., Williams, G. M., Fraser, J. D., & Brimble, M. A. Synthesis of a dicarba analogue of human beta-defensin-1 using a combined ring closing metathesis-native chemical ligation strategy. Organic Letters (2012) 14(3): 878-881.
Henare, K., Wang, L., Wang, L. C., Thomsen, L., Tijono, S., Chen, C. J., Winkler, S., Dunbar, P. R., Print, C., & Ching, L. M. Dissection of stromal and cancer cell-derived signals in melanoma xenografts before and after treatment with DMXAA. British Journal of Cancer (2012) 106(6): 1134-1147.
Herbert, K. R., Williams, G. M., Cooper, G. J. S., & Brimble, M. A. Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin. Organic and Biomolecular Chemistry (2012) 10(6): 1137-1144.
Hermans, S. J., Baker, H. M., Sequeira, R. P., Langley, R. J., Baker, E. N., & Fraser, J. D. Structural and functional properties of staphylococcal superantigen-like protein 4. Infection and Immunity (2012) 80(11): 4004-4013.
Whiting, L., Danaher, R. N., Ruggiero, K., Lee, C. C., Chaussade, C., Mulvey, T., Phillips, A., & Loomes, K. M. D-chiro-inositol attenuates epinephrine-stimulated hepatic glucose output in the isolated perfused liver independently of insulin. Hormone and Metabolic Research (2012).
Wang, L., Hurley, D. G., Watkins, W., Araki, H., Tamada, Y., Muthukaruppan, A., Ranjard, L., Derkac, E., Imoto, S., Miyano, S., Crampin, E. J., & Print, C. G. Cell cycle gene networks are associated with melanoma prognosis. PLoS ONE (2012) 7(4): e34247.
Wang, Y. P., Gjuvsland, A. B., Vik, J. O., Smith, N. P., Hunter, P. J., & Omholt, S. W. Parameters in dynamic models of complex traits are containers of missing heritability. PLoS Computational Biology (2012) 8(4): e1002459.
Watkins, H. A., Au, M., & Hay, D. L. The structure of secretin family GPCR peptide ligands: Implications for receptor pharmacology and drug development. Drug Discovery Today (2012) 17(17-18): 1006-1014.
Watkins, H. A., & Hay, D. L. Recent progress in unraveling the complexities of receptor biology: Towards new therapeutics. Expert Review of Clinical Pharmacology (2012) 5(2): 145-147.
Wilmes, A., Hanna, R., Heathcott, R. W., Northcote, P. T., Atkinson, P. H., Bellows, D. S., & Miller, J. H. Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae. Gene (2012) 497(2): 140- 146.
Woods, T. M., Kamalov, M., Harris, P. W. R., Cooper, G. J. S., & Brimble, M. Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides. Organic Letters (2012) 14(22): 5740-5743.
Yeung, H., Lee, D. J., Williams, G. M., Harris, P. W. R., Dunbar, R. P., & Brimble, M. A. A method for the generation of Pam(2)Cys-based lipopeptide mimics via CuAAC click chemistry. Synlett (2012) 11: 1617-1620.
Yuen, T. Y., & Brimble, M. A. Total synthesis of 7’,8’-dihydroaigialospirol. Organic Letters (2012) 14(19): 5154-5157.
Hickey, A. J. R., Jüllig, M., Aitken, J., Loomes, K., Hauber, M. E., & Phillips, A. R. J. Birds and longevity: Does flight driven aerobicity provide an oxidative sink? Ageing Research Reviews (2012) 11(2): 242-253.
Hobbs, J. K., Shepherd, C., Saul, D. J., Demetras, N. J., Haaning, S., Monk, C. R., Daniel, R. M., & Arcus, V. L. On the origin and evolution of thermophily: Reconstruction of functional precambrian enzymes from ancestors of Bacillus. Molecular Biology and Evolution (2012) 29(2): 825-835.
Horsfield, J. A., Print, C. G., & Monnich, M. Diverse developmental disorders from the one ring: Distinct molecular pathways underlie the cohesinopathies. Frontiers in Genetics (2012) 3: 171.
Huisman, F. H. A., Koon, N., Bulloch, E. M. M., Baker, H. M., Baker, E. N., Squire, C. J., & Parker, E. J. Removal of the C-terminal regulatory domain of alpha-isopropylmalate synthase disrupts functional substrate binding. Biochemistry (2012) 51(11): 2289- 2297.
Hume, P., Furkert, D. P., & Brimble, M. A. Regioselective iridium(I)-catalysed remote borylation of oxygenated naphthalenes. Tetrahedron Letters (2012) 53(29): 3771- 3773.
Hume, P. A., Brimble, M. A., & Reynisson, J. The bioreductive alkylation of DNA by kalafungin: A theoretical investigation. Australian Journal of Chemistry (2012) 65(4): 402-408.
Hume, P. A., Brimble, M. A., & Reynisson, J. DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems. Computational and Theoretical Chemistry (2012).
Hung, K. Y., Harris, P. W. R., & Brimble, M. A. Synthesis of the peptaibol framework of the anticancer agent culicinin D: Stereochemical assignment of the AHMOD moiety. Organic Letters (2012) 14(22): 5784-5787.
Hunn, M. K., Farrand, K. J., Broadley, K. W. R., Weinkove, R., Ferguson, P., Miller, R. J., Field, C. S., Petersen, T., McConnell, M. J., & Hermans, I. F. Vaccination with irradiated tumor cells pulsed with an adjuvant that stimulates NKT cells is an effective treatment for glioma. Clinical Cancer Research (2012) 18(23): 6446-6459.
Hunter, F. W., Wang, J., Patel, R., Hsu, H. L., Hickey, A. J. R., Hay, M. P., & Wilson, W. R. Homologous recombination repair-dependent cytotoxicity of the benzotriazine di- N-oxide CEN-209: Comparison with other hypoxia-activated prodrugs. Biochemical Pharmacology (2012) 83(5): 574-585.
Hurley, D., Araki, H., Tamada, Y., Dunmore, B., Sanders, D., Humphreys, S., Affara, M., Imoto, S., Yasuda, K., Tomiyasu, Y., Tashiro, K., Savoie, C., Cho, V., Smith, S., Kuhara, S., Miyano, S., Charnock-Jones, D. S., Crampin, E. J., & Print, C. G. Gene network inference and visualization tools for biologists: Application to new human transcriptome datasets. Nucleic Acids Research (2012) 40(6): 2377-2398.
Jackson, V. J., Yosaatmadja, Y., Flanagan, J. U., & Squire, C. J. Structure of AKR1C3 with 3-phenoxybenzoic acid bound. Acta Crystallographica Section F: Structural Biology and Crystallization Communications (2012) 68(4): 409-413.
Jamieson, S. M. F., Brooke, D. G., Heinrich, D., Atwell, G. J., Silva, S., Hamilton, E. J., Turnbull, A. P., Rigoreau, L. J. M., Trivier, E., Soudy, C., Samlal, S. S., Owen, P. J., Schroeder, E., Raynham, T., Flanagan, J. U., & Denny, W. A. 3-(3,4-dihydroisoquinolin-2(1 H)-ylsulfonyl)benzoic acids: Highly potent and selective inhibitors of the type 5 17-beta-hydroxysteroid dehydrogenase AKR1C3. Journal of Medicinal Chemistry (2012) 55(17): 7746-7758.
Jiao, W., Hutton, R. D., Cross, P. J., Jameson, G. B., & Parker, E. J. Dynamic crosstalk among remote binding sites: The molecular basis for unusual synergistic allostery. Journal of Molecular Biology (2012) 415(4): 716-726.
Jiao, W. T., & Parker, E. J. Using a combination of computational and experimental techniques to understand the molecular basis for protein allostery. Structural and Mechanistic Enzymology: Bringing Together Experiments and Computing (2012) 87: 391-413.
Kang, H. J., & Baker, E. N. Structure and assembly of Gram-positive bacterial pili: Unique covalent polymers. Current Opinion in Structural Biology (2012) 22(2): 200- 207.
Kaur, H., Heapy, A. M., & Brimble, M. A. Synthesis of the all-l cyclopentapeptides versicoloritides A, B, and C. Synlett (2012) 23(15): 2284-2288.
Kaur, H., Heapy, A. M., & Brimble, M. A. Synthesis of the antifungal cyclic peptides tunicyclins C and D. Synlett (2012) 2: 275-277.
Kendall, J. D., Giddens, A. C., Tsang, K. Y., Frédérick, R., Marshall, E. S., Singh, R., Lill, C. L., Lee, W. J., Kolekar, S., Chao, M., Malik, A., Yu, S., Chaussade, C., Buchanan, C., Rewcastle, G. W., Baguley, B. C., Flanagan, J. U., Jamieson, S. M. F., Denny, W. A., & Shepherd, P. R. Novel pyrazolo[1,5-a]pyridines as p110alpha-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR. Bioorganic and Medicinal Chemistry (2012) 20(1): 58-68.
Kendall, J. D., O’Connor, P. D., Marshall, A. J., Frédérick, R., Marshall, E. S., Lill, C. L., Lee, W. J., Kolekar, S., Chao, M., Malik, A., Yu, S., Chaussade, C., Buchanan, C., Rewcastle, G. W., Baguley, B. C., Flanagan, J. U., Jamieson, S. M. F., Denny, W. A., & Shepherd, P. R. Discovery of pyrazolo[1,5-a]pyridines as p110alpha-selective PI3 kinase inhibitors. Bioorganic and Medicinal Chemistry (2012) 20(1): 69-85.
Kowalczyk, R., Brimble, M. A., Callon, K. E., Watson, M., & Cornish, J. How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosis. Bioorganic and Medicinal Chemistry (2012) 20(20): 6011-6018.
Kowalczyk, R., Harris, P. W. R., Brimble, M. A., Callon, K. E., Watson, M., & Cornish, J. Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis. Bioorganic and Medicinal Chemistry (2012) 20(8): 2661-2668.
Kueh, J. T. B., Choi, K. W., & Brimble, M. A. Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds. Organic and Biomolecular Chemistry (2012) 10(30): 5993-6002.
Lancaster, G. I., Skiba, B., Yang, C., Nicholls, H. T., Langley, K. G., Chan, M. H., Bruce, C. R., Rewcastle, G. W., Shepherd, P. R., Karin, M., & Febbraio, M. A. IkappaB kinase beta (IKKbeta) does not mediate feedback inhibition of the insulin signalling cascade. Biochemical Journal (2012) 442(3): 723-732.
Lasham, A., Samuel, W., Cao, H., Patel, R., Mehta, R., Stern, J. L., Reid, G., Woolley, A. G., Miller, L. D., Black, M. A., Shelling, A. N., Print, C. G., & Braithwaite, A. W. YB-1, the E2F pathway, and regulation of tumor cell growth. Journal of the National Cancer Institute (2012) 104(2): 133-146.
Lee, D. J., Yang, S. H., Williams, G. M., & Brimble, M. A. Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazolelinked glycoclusters to MUC1 peptides using click chemistry. Journal of Organic Chemistry (2012) 77(17): 7564-7571.
Lim, S. N., Kuhn, S., Hyde, E., & Ronchese, F. Combined TLR stimulation with Pam3Cys and Poly I: C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy. Journal of Immunotherapy (2012) 35(9): 670-679.
Linke, C., Siemens, N., Middleditch, M. J., Kreikemeyer, B., & Baker, E. N. Purification, crystallization and preliminary crystallographic analysis of the adhesion domain of Epf from Streptococcus pyogenes. Acta Crystallographica Section F: Structural Biology and Crystallization Communications (2012) 68(7): 793-797.
Linke, C., Siemens, N., Oehmcke, S., Radjainia, M., Law, R. H. P., Whisstock, J. C., Baker, E. N., & Kreikemeyer, B. The extracellular protein factor epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an n-terminal domain containing a carbohydrate-binding module. Journal of Biological Chemistry (2012) 287(45): 38178-38189.
Liu, X., Chia, E., Shaw, O. M., Martin, W. J., & Harper, J. L. Rapid CCL2 release by membrane stromal cells initiates monosodium urate crystal-induced monocyte recruitment in a peritoneal model of gouty inflammation. European Journal of Inflammation (2012) 10(2): 165-174.
McKee, S. J., Young, V. L., Clow, F., Hayman, C. M., Baird, M. A., Hermans, I. F., Young, S. L., & Ward, V. K. Virus-like particles and a-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses. Journal of Controlled Release (2012) 159(3): 338-345.
McLeod, M. C., Brimble, M. A., Rathwell, D. C. K., Wilson, Z. E., & Yuen, T. Y. Synthetic approaches to [5,6]-benzannulated spiroketal natural products. Pure and Applied Chemistry (2012) 84(6): 1379-1390.
McLeod, M. C., Wilson, Z. E., & Brimble, M. A. Formal synthesis of berkelic acid: A lesson in alpha-alkylation chemistry. Journal of Organic Chemistry (2012) 77(1): 400-416.
Noble, D., Kurachi, Y., Hunter, P., Wang, X., Gordon, M., & Boron, W. Physiology without borders 2. Physiology (2012) 27(1): 2.
Pantham, P., Rosario, R., Chen, Q., Print, C. G., & Chamley, L. W. Transcriptomic analysis of placenta affected by antiphospholipid antibodies: following the TRAIL of trophoblast death. Journal of Reproductive Immunology (2012) 94(2): 151-154.
Papst, S., Noisier, A., Brimble, M. A., Yang, Y., & Krissansen, G. W. Tyrosine modified analogues of the alpha4beta7 integrin inhibitor biotin-R8ERY prepared via Click Chemistry: Synthesis and biological evaluation. Bioorganic and Medicinal Chemistry (2012) 20(8): 2638-2644.
Papst, S., Noisier, A. F. M., Brimble, M. A., Yang, Y., Chan, Y. C., & Krissansen, G. W. Synthesis and SAR of a library of cell-permeable biotin-R8ERY*peptidomimetics inhibiting alpha4beta7 integrin mediated adhesion of TK-1 cells to MAdCAM -1-Fc. Australian Journal of Chemistry (2012) 65(9): 1349-1358.
Papst, S., Noisier, A. F. M., Brimble, M. A., Yang, Y., & Krissansen, G. W. Synthesis and biological evaluation of tyrosine modified analogues of the alpha4beta7 integrin inhibitor biotin-R8ERY. Bioorganic and Medicinal Chemistry (2012) 20(17): 5139-5149.
Peltier, R., Siah, W. R., Williams, G. V. M., Brimble, M. A., Tilley, R. D., & Williams, D. E. Novel phosphopeptides as surface-active agents in iron nanoparticle synthesis. Australian Journal of Chemistry (2012) 65(6): 680-685.
Poyner, D. R., & Hay, D. L. Secretin family (Class B) G protein-coupled receptors - From molecular to clinical perspectives. British Journal of Pharmacology (2012) 166(1): 1-3.
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