Source: http://ijsrset.com/IJSRSET184313
Timestamp: 2019-04-20 04:17:30+00:00

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A straightforward convenient and eco-friendly methodology is developed for the synthesis of substituted 2-arylbenzimidazoles by using malic acid as a catalyst in aqueous medium. O-phenylenediamines and aromatic aldehydes condenses together to give benzimidazole derivatives. This methodology uses easily available non-toxic naturally occurring malic acid as a catalyst. The reaction is very simple, convenient and straightforward and gives moderate to high yields of 2-arylbenzimidazoles.
Prof. John Barnabas Post Graduate School for Biological Studies, Department of Chemistry, Ahmednagar College, Ahmednagar, Maharashtra, India.
O-Phenylenediamine, Benzimidazole, Aldehyde, Malic Acid.
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