CELEX: 32021R0849
Language: en
Date: 2021-03-11 00:00:00
Title: Commission Delegated Regulation (EU) 2021/849 of 11 March 2021 amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)

28.5.2021   
               
               
                  EN
               
               
                  Official Journal of the European Union
               
               
                  L 188/27
               
            
         COMMISSION DELEGATED REGULATION (EU) 2021/849
         of 11 March 2021
         amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures
         (Text with EEA relevance)
         THE EUROPEAN COMMISSION,
         Having regard to the Treaty on the Functioning of the European Union,
         Having regard to Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (1), and in particular Article 37(5) thereof,
         Whereas:
         
                     (1)
                  
                  
                     Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008 contains the list of harmonised classification and labelling of hazardous substances based on the criteria set out in Parts 2 to 5 of Annex I to that Regulation.
                  
               
                     (2)
                  
                  
                     Proposals to introduce harmonised classification and labelling of certain substances and to update or delete the harmonised classification and labelling of certain other substances have been submitted to the European Chemicals Agency (‘Agency’) pursuant to Article 37 of Regulation (EC) No 1272/2008. The Committee for Risk Assessment of the Agency (RAC) adopted opinions (2) on those proposals, after having taken account of the comments received from the parties concerned. Those RAC opinions are:
                     
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning 1,2,4-triazole,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning 1,4-dioxane,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning benzyl salicylate,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning flumioxazin (ISO),
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning mancozeb (ISO),
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning M-factors for long-term aquatic hazard for the copper substances listed in Commission Regulation (EU) 2016/1179,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning N-{2-[[1,1'-bi(cyclopropyl)]-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide; sedaxane,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning N-methoxy-N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide; pydiflumetofen,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning p-cymene; 1-isopropyl-4-methylbenzene,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning p-mentha-1,3-diene; alpha-terpinene; 1-isopropyl-4-methylcyclohexa-1,3-diene,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning prothioconazole,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning (R)-p-mentha-1,8-diene; d-limonene,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning thiophanate-methyl,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning tolclofos-methyl (ISO); O-(2,6-dichloro-p-tolyl) O,O-dimethyl thiophosphate,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning tolpyralate,
                              
                           
                                 —
                              
                              
                                 Opinion of 15 March 2019 concerning trinickel disulphide,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning azamethiphos,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning 2-phenoxyethanol,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning 2,2-dibromo-2-cyanoacetamide,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning 3-aminomethyl-3,5,5-trimethylcyclohexylamine,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning diflufenican (ISO) N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-3-pyridinecarboxamide,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning imidacloprid (ISO); 1-(6-chloropyridin-3-ylmethyl)-N-nitroimidazolidin-2-ylidenamine,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning pyriofenone,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning S-abscisic acid,
                              
                           
                                 —
                              
                              
                                 Opinion of 13 June 2019 concerning tetrakis(2,6-dimethylphenyl)-m-phenylene biphosphate,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning 1,2-epoxy-4-epoxyethylcyclohexane,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning 4-methylpentan-2-one,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning boric acid; diboron trioxide; tetraboron disodium heptaoxide hydrate; disodium tetraborate anhydrous; orthoboric acid sodium salt; disodium tetraborate decahydrate; disodium tetraborate pentahydrate,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning citric acid,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning clomazone,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning desmedipham,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning dimethomorph,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning emamectin benzoate,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning esfenvalerate (ISO) (S)-α-cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl)-3-methylbutyrate,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning ethametsulfuron-methyl (ISO),
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning mecoprop-P (ISO); (R)-2-(4-chloro-2-methylphenoxy)propionic acid and its salts,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning methyl salicylate,
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning phenmedipham (ISO),
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning trifloxystrobin (ISO),
                              
                           
                                 —
                              
                              
                                 Opinion of 20 September 2019 concerning triticonazole,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning 1,4-dimethylnaphthalene,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3R,4R,5R)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one; 24-epibrassinolide,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning 3-methylpyrazole,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning carbendazim (ISO); methyl benzimidazol-2-ylcarbamate,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning cypermethrin cis/trans +/- 40/60; (RS)-α-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning imazamox (ISO); (RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning tetrafluoroethylene,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning thiamethoxam (ISO); 3-(2-chloro-thiazol-5-ylmethyl)-5-methyl[1,3,5]oxadiazinan-4-ylidene-N-nitroamine,
                              
                           
                                 —
                              
                              
                                 Opinion of 5 December 2019 concerning trinexapac-ethyl (ISO); ethyl 4-[cyclopropyl(hydroxy)methylene]-3,5-dioxocyclohexanecarboxylate.
                              
                           
               
                     (3)
                  
                  
                     Acute Toxicity Estimates (ATE) are mainly used to determine the classification for human health acute toxicity of mixtures containing substances classified for acute toxicity. The inclusion of harmonised ATE values in the entries listed in Annex VI to Regulation (EC) No 1272/2008 facilitates the harmonisation of the classification of mixtures and provides support for enforcement authorities. Following further scientific assessmentsof some substances, ATE values have been derived by the Agency for dicopper oxide, dicopper chloride trihydroxide, tetracopper hexahydroxide sulphate and tetracopper hexahydroxide sulphate hydrate, copper flakes (coated with aliphatic acid), copper(II) carbonate--copper(II) hydroxide (1:1), copper dihydroxide; copper(II) hydroxide, bordeaux mixture; reaction products of copper sulphate with calcium dihydroxide and copper sulphate pentahydrate, in addition to those proposed in the RAC opinions for other substances. Those ATE values should be inserted in the penultimate column of Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008.
                  
               
                     (4)
                  
                  
                     Additional information was received by the Commission contesting the scientific assessment set out in the RAC opinions of 15 March 2019 concerning mancozeb, of 20 September 2019 concerning 4-methylpentan-2-one, and of 20 September 2019 concerning dimethomorph. That information was assessed by the Commission and was not found sufficient to cast doubts on the scientific analysis contained in the RAC opinions.
                  
               
                     (5)
                  
                  
                     The Commission therefore considers appropriate to introduce, update or delete the harmonised classification and labelling of certain substances.
                  
               
                     (6)
                  
                  
                     Regulation (EC) No 1272/2008 should therefore be amended accordingly.
                  
               
                     (7)
                  
                  
                     Compliance with the new or updated harmonised classifications should not be required immediately as a certain period of time is necessary to allow suppliers to adapt the labelling and packaging of substances and mixtures to the new or revised classifications and to sell existing stocks subject to the pre-existing regulatory requirements. That period of time is also necessary to allow suppliers sufficient time to take the actions required to ensure continuing compliance with other legal requirements following the changes made under this Regulation. Such requirements may include those set out in point (f) of Article 22(1) of Regulation (EC) No 1907/2006 of the European Parliament and of the Council (3) or those set out in Article 50 of Regulation (EU) No 528/2012 of the European Parliament and of the Council (4). Suppliers should, however, have the possibility to apply the new or updated harmonised classifications, and to adapt the labelling and packaging accordingly, on a voluntary basis before the date of application of this Regulation and as of the date of entry into force to ensure a high level of protection of human health and of the environment and to provide sufficient flexibility to suppliers,
                  
               HAS ADOPTED THIS REGULATION:
         
            Article 1
            Amendments to Regulation (EC) No 1272/2008
            Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008 is amended as set out in the Annex to this Regulation.
         
         
            Article 2
            Entry into force and application
            This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.
            It shall apply from 17 December 2022.
            By way of derogation from the second paragraph of this Article, substances and mixtures may be classified, labelled and packaged in accordance with this Regulation from its date of entry into force.
         
         
            This Regulation shall be binding in its entirety and directly applicable in all Member States.
            Done at Brussels, 11 March 2021.
            
               
                  For the Commission
               
               
                  The President
               
               Ursula VON DER LEYEN
            
         
         
            (1)  OJ L 353, 31.12.2008, p. 1.
         
            (2)  The opinions are accessible via the following website:https://echa.europa.eu/registry-of-clh-intentions-until-outcome/-/dislist/name/-/ecNumber/-/casNumber/-/dte_receiptFrom/-/dte_receiptTo/-/prc_public_status/Opinion+Adopted/dte_withdrawnFrom/-/dte_withdrawnTo/-/sbm_expected_submissionFrom/-/sbm_expected_submissionTo/-/dte_finalise_deadlineFrom/-/dte_finalise_deadlineTo/-/haz_addional_hazard/-/lec_submitter/-/dte_assessmentFrom/-/dte_assessmentTo/-/prc_regulatory_programme/-/
         
            (3)  Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC (OJ L 396, 30.12.2006, p. 1).
         
            (4)  Regulation (EU) No 528/2012 of the European Parliament and of the Council of 22 May 2012 concerning the making available on the market and use of biocidal products (OJ L 167, 27.6.2012, p. 1).
      
      
         
            ANNEX
            In Annex VI to Regulation (EC) No 1272/2008, Table 3 of Part 3 is amended as follows:
            
                        (1)
                     
                     
                        the following entries are inserted:
                        
                                    
                                       Index No
                                    
                                 
                                 
                                    
                                       Chemical Name
                                    
                                 
                                 
                                    
                                       EC No
                                    
                                 
                                 
                                    
                                       CAS No
                                    
                                 
                                 
                                    
                                       Classification
                                    
                                 
                                 
                                    
                                       Labelling
                                    
                                 
                                 
                                    
                                       Specific Conc. Limits, M-
                                       factors and ATE
                                    
                                 
                                 
                                    
                                       Notes
                                    
                                 
                              
                                    
                                       Hazard Class and Category Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Pictogram, Signal Word Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Suppl. Hazard statement Code(s)
                                    
                                 
                              
                                    ‘601-093-00-6
                                 
                                 
                                    1,4-dimethylnaphthalene
                                 
                                 
                                    209-335-9
                                 
                                 
                                    571-58-4
                                 
                                 
                                    Acute Tox. 4
                                    Asp. Tox. 1
                                    Eye Irrit. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 3
                                 
                                 
                                    H302
                                    H304
                                    H319
                                    H400
                                    H412
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H302
                                    H304
                                    H319
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1 300  mg/kg bw
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘601-094-00-1
                                 
                                 
                                    1-isopropyl-4-methylbenzene;
                                    
                                       p-cymene
                                 
                                 
                                    202-796-7
                                 
                                 
                                    99-87-6
                                 
                                 
                                    Flam. Liq. 3
                                    Acute Tox. 3
                                    Asp. Tox. 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H226
                                    H331
                                    H304
                                    H411
                                 
                                 
                                    GHS02
                                    GHS06
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H226
                                    H331
                                    H304
                                    H411
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 3 mg/l (vapours)’
                                 
                                 
                                     
                                 
                              
                                    ‘601-095-00-7
                                 
                                 
                                    
                                       p-mentha-1,3-diene; 1-isopropyl-4-methylcyclohexa-1,3-diene;
                                    alpha-terpinene
                                 
                                 
                                    202-795-1
                                 
                                 
                                    99-86-5
                                 
                                 
                                    Flam. Liq. 3
                                    Acute Tox. 4
                                    Skin Sens. 1
                                    Asp. Tox. 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H226
                                    H302
                                    H317
                                    H304
                                    H411
                                 
                                 
                                    GHS02
                                    GHS07
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H226
                                    H302
                                    H317
                                    H304
                                    H411
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1 680  mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘602-110-00-X
                                 
                                 
                                    tetrafluoroethylene
                                 
                                 
                                    204-126-9
                                 
                                 
                                    116-14-3
                                 
                                 
                                    Carc. 1B
                                 
                                 
                                    H350
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H350’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘604-095-00-5
                                 
                                 
                                    6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol;
                                    [DBMC]
                                 
                                 
                                    204-327-1
                                 
                                 
                                    119-47-1
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360F
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360F’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘606-152-00-X
                                 
                                 
                                    (5-chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone
                                 
                                 
                                    -
                                 
                                 
                                    688046-61-9
                                 
                                 
                                    Carc. 2
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘607-747-00-7
                                 
                                 
                                    2,2-dibromo-2-cyanoacetamide; [DBNPA]
                                 
                                 
                                    233-539-7
                                 
                                 
                                    10222-01-2
                                 
                                 
                                    Acute Tox. 2
                                    Acute Tox. 3
                                    STOT RE 1
                                    Skin Irrit. 2
                                    Eye Dam. 1
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H330
                                    H301
                                    H372 (respiratory tract) (inhalation)
                                    H315
                                    H318
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS08
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H330
                                    H301
                                    H372 (respiratory tract) (inhalation)
                                    H315
                                    H318
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,24 mg/l (dusts or mists)
                                    oral: ATE = 118 mg/kg bw
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘607-748-00-2
                                 
                                 
                                    [S-(Z,E)]-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid;
                                    
                                       S-abscisic acid
                                 
                                 
                                    244-319-5
                                 
                                 
                                    21293-29-8
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘607-749-00-8
                                 
                                 
                                    methyl salicylate
                                 
                                 
                                    204-317-7
                                 
                                 
                                    119-36-8
                                 
                                 
                                    Repr. 2
                                    Acute Tox. 4
                                    Skin Sens. 1B
                                    Aquatic Chronic 3
                                 
                                 
                                    H361d
                                    H302
                                    H317
                                    H412
                                 
                                 
                                    GHS07
                                    GHS08
                                    Wng
                                 
                                 
                                    H361d
                                    H302
                                    H317
                                    H412
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 890 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘607-750-00-3
                                 
                                 
                                    citric acid
                                 
                                 
                                    201-069-1
                                 
                                 
                                    77-92-9
                                 
                                 
                                    Eye Irrit. 2
                                    STOT SE 3
                                 
                                 
                                    H319
                                    H335
                                 
                                 
                                    GHS07
                                    Wng
                                 
                                 
                                    H319
                                    H335’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-751-00-9
                                 
                                 
                                    ethametsulfuron-methyl (ISO);
                                    methyl 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate
                                 
                                 
                                    -
                                 
                                 
                                    97780-06-8
                                 
                                 
                                    Eye Irrit. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H319
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H319
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1 000 
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘607-752-00-4
                                 
                                 
                                    trinexapac-ethyl (ISO);
                                    ethyl 4-[cyclopropyl(hydroxy)methylene]-3,5-dioxocyclohexanecarboxylate
                                 
                                 
                                    -
                                 
                                 
                                    95266-40-3
                                 
                                 
                                    STOT RE 2
                                    Skin Sens. 1B
                                    Aquatic Chronic 1
                                 
                                 
                                    H373 (gastrointestinal tract)
                                    H317
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H373 (gastrointestinal tract)
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘607-753-00-X
                                 
                                 
                                    (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3R,4R,5R)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one; 24-epibrassinolide
                                 
                                 
                                    -
                                 
                                 
                                    78821-43-9
                                 
                                 
                                    Aquatic Chronic 4
                                 
                                 
                                    H413
                                 
                                 
                                     
                                 
                                 
                                    H413’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-754-00-5
                                 
                                 
                                    benzyl salicylate
                                 
                                 
                                    204-262-9
                                 
                                 
                                    118-58-1
                                 
                                 
                                    Skin Sens. 1B
                                 
                                 
                                    H317
                                 
                                 
                                    GHS07
                                    Wng
                                 
                                 
                                    H317’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-755-00-0
                                 
                                 
                                    (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate;
                                    tolpyralate
                                 
                                 
                                    -
                                 
                                 
                                    1101132-67-5
                                 
                                 
                                    Carc. 2
                                    Repr. 2
                                    STOT RE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H361fd
                                    H373 (eye)
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H361fd
                                    H373 (eye)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘613-337-00-9
                                 
                                 
                                    prothioconazole (ISO);
                                    2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione
                                 
                                 
                                    -
                                 
                                 
                                    178928-70-6
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘613-338-00-4
                                 
                                 
                                    azamethiphos (ISO); S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl thiophosphate
                                 
                                 
                                    252-626-0
                                 
                                 
                                    35575-96-3
                                 
                                 
                                    Carc. 2
                                    Acute Tox. 3
                                    Acute Tox. 4
                                    STOT SE 1
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H331
                                    H302
                                    H370 (nervous system)
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H351
                                    H331
                                    H302
                                    H370 (nervous system)
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,5 mg/l (dusts or mists)
                                    oral: ATE = 500 mg/kg bw
                                    M = 1 000 
                                    M = 1 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘613-339-00-X
                                 
                                 
                                    3-methylpyrazole
                                 
                                 
                                    215-925-7
                                 
                                 
                                    1453-58-3
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 4
                                    STOT RE 2
                                    Skin Corr. 1
                                    Eye Dam. 1
                                 
                                 
                                    H360D
                                    H302
                                    H373 (lung)
                                    H314
                                    H318
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS05
                                    Dgr
                                 
                                 
                                    H360D
                                    H302
                                    H373 (lung)
                                    H314
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 500 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘613-340-00-5
                                 
                                 
                                    clomazone (ISO); 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one
                                 
                                 
                                    -
                                 
                                 
                                    81777-89-1
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H302
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H332
                                    H302
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 4,85 mg/l (dusts or mists)
                                    oral: ATE = 768 mg/kg bw
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘614-030-00-2
                                 
                                 
                                    emamectin benzoate (ISO); (4"R)-4"-deoxy-4"-(methylamino) avermectin B1 benzoate
                                 
                                 
                                    -
                                 
                                 
                                    155569-91-8
                                 
                                 
                                    Acute Tox. 3
                                    Acute Tox. 3
                                    Acute Tox. 3
                                    STOT SE 1
                                    STOT RE 1
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H331
                                    H311
                                    H301
                                    H370 (nervous system)
                                    H372 (nervous system)
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS05
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H331
                                    H311
                                    H301
                                    H370 (nervous system)
                                    H372 (nervous system)
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation:
                                    ATE = 0,663
                                    mg/l (dusts or mists)
                                    dermal:
                                    ATE = 300
                                    mg/kg bw
                                    oral: ATE =
                                    60 mg/kg bw
                                    STOT RE 1; H372: C ≥ 5 %; STOT RE 2; H373: 0,5 % ≤ C < 5 %
                                    M = 10 000 
                                    M = 10 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘616-234-00-7
                                 
                                 
                                    
                                       N-methoxy-N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide; pydiflumetofen
                                 
                                 
                                    -
                                 
                                 
                                    1228284-64-7
                                 
                                 
                                    Carc. 2
                                    Repr. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H361f
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H361f
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘616-235-00-2
                                 
                                 
                                    
                                       N-{2-[[1,1'-bi(cyclopropyl)]-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide; sedaxane
                                 
                                 
                                    -
                                 
                                 
                                    874967-67-6
                                 
                                 
                                    Carc. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H351
                                    H400
                                    H411
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                  
                        (2)
                     
                     
                        the entries corresponding to index numbers 005-007-00-2; 005-008-00-8; 005-011-00-4; 005-011-01-1; 005-011-02-9; 006-069-00-3; 006-076-00-1; 015-113-00-0; 028-007-00-4; 029-002-00-X; 029-015-00-0; 029-016-00-6; 029-017-00-1; 029-018-00-7; 029-019-01-X; 029-020-00-8; 029-021-00-3; 029-022-00-9; 029-023-00-4; 601-029-00-7; 601-096-00-2; 603-024-00-5; 603-066-00-4; 603-098-00-9; 606-004-00-4; 607-421-00-4; 607-424-00-0; 607-434-00-5; 608-058-00-4; 612-067-00-9; 612-252-00-4; 613-048-00-8; 613-102-00-0; 613-111-00-X; 613-166-00-X; 613-208-00-7; 613-267-00-9; 613-282-00-0; 616-032-00-9; 616-106-00-0 and 616-113-00-9 are replaced by the following entries respectively:
                        
                                    
                                       Index No
                                    
                                 
                                 
                                    
                                       Chemical Name
                                    
                                 
                                 
                                    
                                       EC No
                                    
                                 
                                 
                                    
                                       CAS No
                                    
                                 
                                 
                                    
                                       Classification
                                    
                                 
                                 
                                    
                                       Labelling
                                    
                                 
                                 
                                    
                                       Specific Conc. Limits, M- factors and ATE
                                    
                                 
                                 
                                    
                                       Notes
                                    
                                 
                              
                                    
                                       Hazard Class and Category Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Pictogram, Signal Word Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Suppl. Hazard statement Code(s)
                                    
                                 
                              
                                    ‘005-007-00-2
                                 
                                 
                                    boric acid [1]
                                    boric acid [2]
                                 
                                 
                                    233-139-2 [1]
                                    234-343-4 [2]
                                 
                                 
                                    10043-35-3 [1]
                                    11113-50-1 [2]
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘005-008-00-8
                                 
                                 
                                    diboron trioxide
                                 
                                 
                                    215-125-8
                                 
                                 
                                    1303-86-2
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘005-011-00-4
                                 
                                 
                                    tetraboron disodium heptaoxide, hydrate; [1]
                                    disodium tetraborate, anhydrous; [2]
                                    orthoboric acid, sodium salt [3]
                                    disodium tetraborate decahydrate [4]
                                    disodium tetraborate pentahydrate [5]
                                 
                                 
                                    235-541-3 [1]
                                    215-540-4 [2]
                                    237-560-2 [3]
                                    215-540-4 [4]
                                    215-540-4 [5]
                                 
                                 
                                    12267-73-1 [1]
                                    1330-43-4 [2]
                                    13840-56-7 [3]
                                    1303-96-4 [4]
                                    12179-04-3 [5]
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘006-069-00-3
                                 
                                 
                                    thiophanate-methyl (ISO);
                                    dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate;
                                    dimethyl 4,4′-(o-phenylene)bis(3-thioallophanate)
                                 
                                 
                                    245-740-7
                                 
                                 
                                    23564-05-8
                                 
                                 
                                    Carc. 2
                                    Muta. 2
                                    Acute Tox. 4
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H341
                                    H332
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H341
                                    H332
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 1,7 mg/l
                                    (dusts and mists)
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘006-076-00-1
                                 
                                 
                                    mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt
                                 
                                 
                                    -
                                 
                                 
                                    8018-01-7
                                 
                                 
                                    Carc. 2
                                    Repr. 1B
                                    STOT RE 2
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H360D
                                    H373 (thyroid, nervous system)
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Dgr
                                 
                                 
                                    H351
                                    H360D
                                    H373 (thyroid, nervous system)
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘015-113-00-0
                                 
                                 
                                    tolclofos-methyl (ISO);
                                    
                                       O-(2,6-dichloro-p-tolyl) O,O-dimethyl thiophosphate
                                 
                                 
                                    260-515-3
                                 
                                 
                                    57018-04-9
                                 
                                 
                                    Skin Sens. 1B
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘028-007-00-4
                                 
                                 
                                    trinickel disulfide;
                                    nickel subsulfide; [1]
                                    heazlewoodite [2]
                                 
                                 
                                    234-829-6 [1]
                                    - [2]
                                 
                                 
                                    12035-72-2 [1]
                                    12035-71-1 [2]
                                 
                                 
                                    Carc. 1A
                                    Muta. 2
                                    Acute Tox. 3
                                    STOT RE 1
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H350i
                                    H341
                                    H331
                                    H372**
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS06
                                    GHS09
                                    Dgr
                                 
                                 
                                    H350i
                                    H341
                                    H331
                                    H372**
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation:
                                    ATE = 0,92 mg/l
                                    (dusts or mists)’
                                 
                                 
                                     
                                 
                              
                                    ‘029-002-00-X
                                 
                                 
                                    dicopper oxide;
                                    copper (I) oxide
                                 
                                 
                                    215-270-7
                                 
                                 
                                    1317-39-1
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H302
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H332
                                    H302
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 3,34 mg/l (dusts or mists)
                                    oral: ATE = 500 mg/kg bw
                                    M = 100
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-015-00-0
                                 
                                 
                                    copper thiocyanate
                                 
                                 
                                    214-183-1
                                 
                                 
                                    1111-67-7
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                    EUH032
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-016-00-6
                                 
                                 
                                    copper(II) oxide
                                 
                                 
                                    215-269-1
                                 
                                 
                                    1317-38-0
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 100
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-017-00-1
                                 
                                 
                                    dicopper chloride trihydroxide
                                 
                                 
                                    215-572-9
                                 
                                 
                                    1332-65-6
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 3
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H301
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS09
                                    Dgr
                                 
                                 
                                    H332
                                    H301
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 2,83 mg/l (dusts or mists)
                                    oral: ATE = 299 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-018-00-7
                                 
                                 
                                    tetracopper hexahydroxide sulphate; [1]
                                    tetracopper hexahydroxide sulphate hydrate [2]
                                 
                                 
                                    215-582-3 [1]
                                    215-582-3 [2]
                                 
                                 
                                    1333-22-8 [1]
                                    12527-76-3 [2]
                                 
                                 
                                    Acute Tox. 4
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H302
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 500 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-019-01-X
                                 
                                 
                                    copper flakes (coated with aliphatic acid)
                                 
                                 
                                    -
                                 
                                 
                                    -
                                 
                                 
                                    Acute Tox. 3
                                    Acute Tox. 4
                                    Eye Irrit. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H331
                                    H302
                                    H319
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS09
                                    Dgr
                                 
                                 
                                    H331
                                    H302
                                    H319
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,733 mg/l (dusts or mists)
                                    oral: ATE = 500 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-020-00-8
                                 
                                 
                                    copper(II) carbonate—copper(II) hydroxide (1:1)
                                 
                                 
                                    235-113-6
                                 
                                 
                                    12069-69-1
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    Eye Irrit. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H302
                                    H319
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H332
                                    H302
                                    H319
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 1,2 mg/l (dusts or mists)
                                    oral: ATE = 500 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-021-00-3
                                 
                                 
                                    copper dihydroxide;
                                    copper(II) hydroxide
                                 
                                 
                                    243-815-9
                                 
                                 
                                    20427-59-2
                                 
                                 
                                    Acute Tox. 2
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H330
                                    H302
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H330
                                    H302
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,47 mg/l (dusts or mists)
                                    oral: ATE = 500 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-022-00-9
                                 
                                 
                                    bordeaux mixture;
                                    reaction products of copper sulphate with calcium dihydroxide
                                 
                                 
                                    -
                                 
                                 
                                    8011-63-0
                                 
                                 
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H332
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 1,97 mg/l (dusts or mists)
                                    M = 10
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘029-023-00-4
                                 
                                 
                                    copper sulphate pentahydrate
                                 
                                 
                                    231-847-6
                                 
                                 
                                    7758-99-8
                                 
                                 
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H302
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 481 mg/kg bw
                                    M = 10
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘601-029-00-7
                                 
                                 
                                    dipentene;
                                    limonene [1]
                                    (S)-p-mentha-1,8-diene; l-limonene [2]
                                    
                                       trans-1-methyl-4-(1-methylvinyl)cyclohexene; [3]
                                    (±)-1-methyl-4-(1-methylvinyl)cyclohexene [4]
                                 
                                 
                                    205-341-0 [1]
                                    227-815-6 [2]
                                    229-977-3 [3]
                                    231-732-0 [4]
                                 
                                 
                                    138-86-3 [1]
                                    5989-54-8 [2]
                                    6876-12-6 [3]
                                    7705-14-8 [4]
                                 
                                 
                                    Flam. Liq. 3
                                    Skin Irrit. 2
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H226
                                    H315
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS02
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H226
                                    H315
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                    C’
                                 
                              
                                    ‘601-096-00-2
                                 
                                 
                                    (R)-p-mentha-1,8-diene;
                                    d-limonene
                                 
                                 
                                    227-813-5
                                 
                                 
                                    5989-27-5
                                 
                                 
                                    Flam. Liq. 3
                                    Skin Irrit. 2
                                    Skin Sens. 1B
                                    Asp. Tox. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 3
                                 
                                 
                                    H226
                                    H315
                                    H317
                                    H304
                                    H400
                                    H412
                                 
                                 
                                    GHS02
                                    GHS07
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H226
                                    H315
                                    H317
                                    H304
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘603-024-00-5
                                 
                                 
                                    1,4-dioxane
                                 
                                 
                                    204-661-8
                                 
                                 
                                    123-91-1
                                 
                                 
                                    Flam. Liq. 2
                                    Carc. 1B
                                    STOT SE 3
                                    Eye Irrit. 2
                                 
                                 
                                    H225
                                    H350
                                    H335
                                    H319
                                 
                                 
                                    GHS02
                                    GHS08
                                    GHS07
                                    Dgr
                                 
                                 
                                    H225
                                    H350
                                    H335
                                    H319
                                 
                                 
                                    EUH019
                                    EUH066
                                 
                                 
                                     
                                 
                                 
                                    D’
                                 
                              
                                    ‘603-066-00-4
                                 
                                 
                                    7-oxa-3-oxiranylbicyclo[4.1.0]heptane; 1,2-epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide
                                 
                                 
                                    203-437-7
                                 
                                 
                                    106-87-6
                                 
                                 
                                    Carc. 1B
                                    Muta. 2
                                    Repr. 1B
                                    Acute Tox. 3
                                    Acute Tox. 4
                                 
                                 
                                    H350
                                    H341
                                    H360F
                                    H331
                                    H302
                                 
                                 
                                    GHS08
                                    GHS06
                                    Dgr
                                 
                                 
                                    H350
                                    H341
                                    H360F
                                    H331
                                    H302
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,5 mg/l (dusts or mists)
                                    oral: ATE = 1 847  mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘603-098-00-9
                                 
                                 
                                    2-phenoxyethanol
                                 
                                 
                                    204-589-7
                                 
                                 
                                    122-99-6
                                 
                                 
                                    Acute Tox. 4
                                    STOT SE 3
                                    Eye Dam. 1
                                 
                                 
                                    H302
                                    H335
                                    H318
                                 
                                 
                                    GHS05
                                    GHS07
                                    Dgr
                                 
                                 
                                    H302
                                    H335
                                    H318
                                 
                                 
                                     
                                 
                                 
                                    oral:
                                    ATE = 1 394  mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘606-004-00-4
                                 
                                 
                                    4-methylpentan-2-one; isobutyl methyl ketone
                                 
                                 
                                    203-550-1
                                 
                                 
                                    108-10-1
                                 
                                 
                                    Flam. Liq. 2
                                    Carc. 2
                                    Acute Tox. 4
                                    STOT SE 3
                                    Eye Irrit. 2
                                 
                                 
                                    H225
                                    H351
                                    H332
                                    H336
                                    H319
                                 
                                 
                                    GHS02
                                    GHS07
                                    GHS08
                                    Dgr
                                 
                                 
                                    H225
                                    H351
                                    H332
                                    H336
                                    H319
                                 
                                 
                                    EUH066
                                 
                                 
                                    inhalation: ATE = 11 mg/l (vapours)’
                                 
                                 
                                     
                                 
                              
                                    ‘607-421-00-4
                                 
                                 
                                    cypermethrin (ISO);
                                    α-cyano-3-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; cypermethrin cis/trans +/- 40/60
                                 
                                 
                                    257-842-9
                                 
                                 
                                    52315-07-8
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    STOT SE 3
                                    STOT RE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H332
                                    H302
                                    H335
                                    H373 (nervous system)
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H332
                                    H302
                                    H335
                                    H373 (nervous system)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral; ATE = 500 mg/kg bw
                                    inhalation; ATE = 3,3 mg/l (dusts or mists)
                                    M = 100000
                                    M = 100000’
                                 
                                 
                                     
                                 
                              
                                    ‘607-424-00-0
                                 
                                 
                                    trifloxystrobin (ISO); methyl (E)-methoxyimino-{(E)-α-[1-(α,α,α-trifluoro-m-tolyl)ethylideneaminooxy]-o-tolyl}acetate
                                 
                                 
                                    -
                                 
                                 
                                    141517-21-7
                                 
                                 
                                    Lact.
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H362
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H362
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 100
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘607-434-00-5
                                 
                                 
                                    mecoprop-P (ISO) [1] and its salts;
                                    (R)-2-(4-chloro-2-methylphenoxy)propionic acid [1] and its salts
                                 
                                 
                                    240-539-0 [1]
                                 
                                 
                                    16484-77-8 [1]
                                 
                                 
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H302
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 431 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘608-058-00-4
                                 
                                 
                                    esfenvalerate (ISO);
                                    (S)-α-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-3-methylbutyrate
                                 
                                 
                                    -
                                 
                                 
                                    66230-04-4
                                 
                                 
                                    Acute Tox. 3
                                    Acute Tox. 3
                                    STOT SE 1
                                    STOT RE 2
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H331
                                    H301
                                    H370 (nervous system)
                                    H373
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H331
                                    H301
                                    H370 (nervous system)
                                    H373
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral; ATE = 88,5 mg/kg bw
                                    inhalation; ATE = 0,53 mg/l (dusts or mists)
                                    M = 10 000 
                                    M = 10 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘612-067-00-9
                                 
                                 
                                    3-aminomethyl-3,5,5-trimethylcyclohexylamine
                                 
                                 
                                    220-666-8
                                 
                                 
                                    2855-13-2
                                 
                                 
                                    Acute Tox. 4
                                    Skin Corr. 1B
                                    Eye Dam. 1
                                    Skin Sens. 1A
                                 
                                 
                                    H302
                                    H314
                                    H318
                                    H317
                                 
                                 
                                    GHS05
                                    GHS07
                                    Dgr
                                 
                                 
                                    H302
                                    H314
                                    H317
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1 030  mg/kg bw
                                    Skin Sens. 1A; H317: C ≥ 0,001 %’
                                 
                                 
                                     
                                 
                              
                                    ‘612-252-00-4
                                 
                                 
                                    imidacloprid (ISO);
                                    (E)-1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine;
                                    (2E)-1-[(6-chloropyridin-3-yl) methyl]-N-nitroimidazolidin-2-imine
                                 
                                 
                                    428-040-8
                                 
                                 
                                    138261-41-3
                                 
                                 
                                    Acute Tox. 3
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H301
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS09
                                    Dgr
                                 
                                 
                                    H301
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 131 mg/kg bw
                                    M = 100
                                    M = 1 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘613-048-00-8
                                 
                                 
                                    carbendazim (ISO); methyl benzimidazol-2-ylcarbamate
                                 
                                 
                                    234-232-0
                                 
                                 
                                    10605-21-7
                                 
                                 
                                    Muta. 1B
                                    Repr. 1B
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H340
                                    H360FD
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H340
                                    H360FD
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘613-102-00-0
                                 
                                 
                                    dimethomorph (ISO); (E,Z)-4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl)morpholine
                                 
                                 
                                    404-200-2
                                 
                                 
                                    110488-70-5
                                 
                                 
                                    Repr. 1B
                                    Aquatic Chronic 2
                                 
                                 
                                    H360F
                                    H411
                                 
                                 
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360F
                                    H411’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘613-111-00-X
                                 
                                 
                                    1,2,4-triazole
                                 
                                 
                                    206-022-9
                                 
                                 
                                    288-88-0
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 4
                                    Eye Irrit. 2
                                 
                                 
                                    H360FD
                                    H302
                                    H319
                                 
                                 
                                    GHS08
                                    GHS07
                                    Dgr
                                 
                                 
                                    H360FD
                                    H302
                                    H319
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1 320  mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘613-166-00-X
                                 
                                 
                                    flumioxazin (ISO);
                                    
                                       N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboximide
                                 
                                 
                                    -
                                 
                                 
                                    103361-09-7
                                 
                                 
                                    Repr. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361d
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361d
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1 000 
                                    M = 1 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘613-208-00-7
                                 
                                 
                                    imazamox (ISO);
                                    (RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid
                                 
                                 
                                    -
                                 
                                 
                                    114311-32-9
                                 
                                 
                                    Repr. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361d
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361d
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘613-267-00-9
                                 
                                 
                                    thiamethoxam (ISO);
                                    3-(2-chloro-thiazol-5-ylmethyl)-5-methyl[1,3,5]oxadiazinan-4-ylidene-N-nitroamine
                                 
                                 
                                    428-650-4
                                 
                                 
                                    153719-23-4
                                 
                                 
                                    Repr. 2
                                    Acute Tox. 4
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361fd
                                    H302
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361fd
                                    H302
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 780 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘613-282-00-0
                                 
                                 
                                    triticonazole (ISO);
                                    (RS)-(E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-methyl)cyclopentanol
                                 
                                 
                                    -
                                 
                                 
                                    138182-18-0
                                 
                                 
                                    Repr. 2
                                    STOT RE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361f
                                    H373
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361f
                                    H373
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘616-032-00-9
                                 
                                 
                                    diflufenican (ISO);
                                    
                                       N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-3-pyridinecarboxamide; 2′,4′-difluoro-2-(α,α,α-trifluoro-m-tolyloxy) nicotinanilide
                                 
                                 
                                    -
                                 
                                 
                                    83164-33-4
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10 000 
                                    M = 1 000 ’
                                 
                                 
                                     
                                 
                              
                                    ‘616-106-00-0
                                 
                                 
                                    phenmedipham (ISO); methyl 3-(3-methylcarbaniloyloxy)carbanilate
                                 
                                 
                                    237-199-0
                                 
                                 
                                    13684-63-4
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘616-113-00-9
                                 
                                 
                                    desmedipham (ISO);
                                    ethyl 3-phenylcarbamoyloxyphenylcarbamate
                                 
                                 
                                    237-198-5
                                 
                                 
                                    13684-56-5
                                 
                                 
                                    Repr. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361d
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361d
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                  
                        (3)
                     
                     
                        the entry corresponding to index number 015-192-00-1 is deleted.