CELEX: 32020R1182
Language: en
Date: 2020-05-19 00:00:00
Title: Commission Delegated Regulation (EU) 2020/1182 of 19 May 2020 amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)

11.8.2020   
               
               
                  EN
               
               
                  Official Journal of the European Union
               
               
                  L 261/2
               
            
         COMMISSION DELEGATED REGULATION (EU) 2020/1182
         of 19 May 2020
         amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures
         (Text with EEA relevance)
         THE EUROPEAN COMMISSION,
         Having regard to the Treaty on the Functioning of the European Union,
         Having regard to Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (1), and in particular Article 37(5) thereof,
         Whereas:
         
                     (1)
                  
                  
                     Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008 contains the list of harmonised classification and labelling of hazardous substances based on the criteria set out in Parts 2 to 5 of Annex I to that Regulation.
                  
               
                     (2)
                  
                  
                     Proposals to introduce harmonised classification and labelling of certain substances and to update or delete the harmonised classification and labelling of certain other substances have been submitted to the European Chemicals Agency (‘Agency’) pursuant to Article 37 of Regulation (EC) No 1272/2008. Based on the opinions (2) on those proposals issued by the Committee for Risk Assessment of the Agency (RAC), as well as on the comments received from the parties concerned, it is appropriate to introduce, update or delete the harmonised classification and labelling of certain substances. Those RAC opinions are:
                     
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning nitric acid ... %[C ≤ 70 %];
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning silicon carbide fibres (with diameter < 3 μm, length > 5 μm and aspect ratio ≥ 3:1);
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning trimethoxyvinylsilane; trimethoxy(vinyl)silane;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning tris(2-methoxyethoxy)vinylsilane; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning dimethyl disulphide;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning granulated copper;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O')copper; bis(N-cyclohexyl-diazenium-dioxy)-copper; [Cu-HDO];
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning dioctyltin dilaurate; [1] stannane, dioctyl-, bis(coco acyloxy) derivs. [2];
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning dibenzo[def,p]chrysene; dibenzo[a,l]pyrene;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning bis(2-(2-methoxyethoxy)ethyl)ether; tetraglyme;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning paclobutrazol (ISO); (2RS,3RS)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning 2,2-bis(bromomethyl)propane-1,3-diol;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning geraniol; (2E)-3,7-dimethylocta-2,6-dien-1-ol;
                              
                           
                                 —
                              
                              
                                 Opinion of 28 January 2019 concerning 2-(4-tert-butylbenzyl)propionaldehyde;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning MCPA-thioethyl (ISO); S-ethyl (4-chloro-2-methylphenoxy)ethanethioate; S-ethyl 4-chloro-o-tolyloxythioacetate;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning diisooctyl phthalate;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning 4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl) amino}furan-2(5H)-one; flupyradifurone;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning thiencarbazone-methyl (ISO); methyl 4- [(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonylsulfamoyl]-5-methylthiophene-3-carboxylate;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning L-(+)-lactic acid; (2S)-2-hydroxypropanoic acid;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning 2-methoxyethyl acrylate;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning glyoxylic acid …%;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate];
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning potassium (oxido-NNO-azoxy)cyclohexane; cyclohexylhydroxydiazene 1-oxide, potassium salt; [K-HDO];
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning mecetronium etilsulfate; N-ethyl-N,N-dimethylhexadecan-1-aminium ethyl sulfate; mecetronium ethyl sulphate [MES];
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning (2RS)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol; mefentrifluconazole;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning oxathiapiprolin (ISO); 1-(4-{4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning pyrithione zinc; (T-4)-bis[1-(hydroxy-.kappa.O) pyridine-2(1H)-thionato-.kappa.S]zinc;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning 3-chloro-4-(chloromethyl)-1-[3-trifluoromethyl)phenyl]pyrrolidin-2-one; flurochloridone (ISO);
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning 4,5-dichloro-2-octyl-2H-isothiazol-3-one; [DCOIT];
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning 2-methyl-1,2-benzothiazol-3(2H)-one; [MBIT];
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide; fluxapyroxad;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning N-(hydroxymethyl)acrylamide; methylolacrylamide; [NMA];
                              
                           
                                 —
                              
                              
                                 Opinion of 15 October 2018 concerning 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2’-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide; penflufen;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning iprovalicarb(ISO); isopropyl [(2S)-3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl]carbamate;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning silthiofam (ISO); N-allyl-4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxamide;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning Margosa, ext. [cold-pressed oil of Azadirachta indica seeds without shells extracted with super-critical carbon dioxide];
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning nitric acid …%[C> 70 %];
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning octamethylcyclotetrasiloxane; [D4];
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning pirimiphos-methyl (ISO); O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl phosphorothioate;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning phosphine;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning dichlorodioctylstannane;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE];
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning lead;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning 2-butoxyethanol; ethylene glycol monobutyl ether;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning m-bis(2,3-epoxypropoxy)benzene; resorcinol diglycidyl ether;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning tribenuron-methyl (ISO); methyl 2- [N-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-N-methylcarbamoylsulfamoyl]benzoate;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning azoxystrobin (ISO); methyl (E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl}-3-methoxyacrylate;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning ethofumesate (ISO); (RS)-2-ethoxy-2,3-dihydro-3,3-dimethylbenzofuran-5-yl methanesulfonate;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning 2,4-dinitrophenol;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning mesotrione (ISO); 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT];
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning hymexazol (ISO); 3-hydroxy-5-methylisoxazole;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning hexythiazox (ISO); trans-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-3-thiazolidine-carboxamide;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning pymetrozine (ISO); (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethylene amino)-1,2,4-triazin-3(2H)-one;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning imiprothrin (ISO); reaction mass of: [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-cis-chrysanthemate; [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-trans-chrysanthemate;
                              
                           
                                 —
                              
                              
                                 Opinion of 14 September 2018 concerning butanone oxime; ethyl methyl ketoxime; ethyl methyl ketone oxime;
                              
                           
                                 —
                              
                              
                                 Opinion of 8 June 2018 concerning bis(α,α-dimethylbenzyl) peroxide;
                              
                           
                                 —
                              
                              
                                 Opinion of 9 March 2018 concerning branched hexatriacontane;
                              
                           
                                 —
                              
                              
                                 Opinion of 30 November 2018 concerning hexyl 2-(1-(diethylaminohydroxyphenyl) methanoyl)benzoate; hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.
                              
                           
               
                     (3)
                  
                  
                     With regard to the substance lead (CAS number 7439-92-1 and index numbers 082-013-00-1 (lead powder; [particle diameter < 1 mm];) and 082-014-00-7 (lead massive; [particle diameter ≥ 1 mm];)), RAC proposed in its opinion of 30 November 2018 to apply the same environmental classification to the massive and the powder form. However, in view of the lower dissolution rate of the massive form, the malleable structure of lead, the specific intentional production of the powder and the different environmental classification between massive and powder forms for existing entries in Annex VI for other metals, further assessment needs to be done by RAC on whether to apply the same environmental classification to the massive as to the powder form of lead. In addition, new scientific data has been made available suggesting that the environmental classification for the massive form as recommended in the RAC opinion might not be appropriate Therefore, the environmental classification for the massive form will not be included in Annex VI to Regulation (EC) No 1272/2008 until RAC has had the opportunity to deliver a revised opinion.
                  
               
                     (4)
                  
                  
                     With regard to the substance 2-butoxyethanol; ethylene glycol monobutyl ether; (CAS number 111-76-2), new scientific data has been made available for the hazard class ‘acute toxicity (inhalation)’ which suggests that the classification for this hazard class as recommended in the RAC opinion, which is based on older data, might not be appropriate. Therefore, this hazard class should not be modified in Annex VI to Regulation (EC) No 1272/2008 until RAC has had the opportunity to deliver a revised opinion based on the new information, while all other hazard classes covered by the RAC opinion should be included.
                  
               
                     (5)
                  
                  
                     Regulation (EC) No 1272/2008 should therefore be amended accordingly.
                  
               
                     (6)
                  
                  
                     Compliance with the new or updated harmonised classifications should not be required immediately as a certain period of time is necessary to allow suppliers to adapt the labelling and packaging of substances and mixtures to the new or revised classifications and to sell existing stocks subject to the pre-existing regulatory requirements. That period of time is also necessary to allow suppliers sufficient time to take the actions required to ensure continuing compliance with other legal requirements following the changes made under this Regulation. Such requirements may include those set out in point (f) of Article 22(1) of Regulation (EC) No 1907/2006 of the European Parliament and of the Council (3) or those set out in Article 50 of Regulation (EU) No 528/2012 of the European Parliament and of the Council (4).
                  
               
                     (7)
                  
                  
                     Suppliers should, however, have the possibility to apply the new classification, labelling and packaging provisions on a voluntary basis before the date of application of this Regulation. This is consistent with the approach taken under Article 61(2) of Regulation (EC) No 1272/2008,
                  
               HAS ADOPTED THIS REGULATION:
         
            Article 1
            Amendments to Regulation (EC) No 1272/2008
            Table 3 of Part 3 of Annex VI to Regulation (EC) No 1272/2008 is amended as set out in the Annex to this Regulation.
         
         
            Article 2
            Entry into force and application
            This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.
            It shall apply from 1 March 2022.
            By way of derogation from the second paragraph of this Article, substances and mixtures may, before 1 March 2022 be classified, labelled and packaged in accordance with Regulation (EC) No 1272/2008 as amended by this Regulation.
         
         
            This Regulation shall be binding in its entirety and directly applicable in all Member States.
            Done at Brussels, 19 May 2020.
            
               
                  For the Commission
               
               
                  The President
               
               Ursula VON DER LEYEN
            
         
         
            (1)  OJ L 353, 31.12.2008, p. 1.
         
            (2)  The opinions are accessible via the following website: https://echa.europa.eu/registry-of-clh-intentions-until-outcome/-/dislist/name/-/ecNumber/-/casNumber/-/dte_receiptFrom/-/dte_receiptTo/-/prc_public_status/Opinion+Adopted/dte_withdrawnFrom/-/dte_withdrawnTo/-/sbm_expected_submissionFrom/-/sbm_expected_submissionTo/-/dte_finalise_deadlineFrom/-/dte_finalise_deadlineTo/-/haz_addional_hazard/-/lec_submitter/-/dte_assessmentFrom/-/dte_assessmentTo/-/prc_regulatory_programme/-/
         
            (3)  Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006
         concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC (OJ L 396, 30.12.2006, p. 1).
         
            (4)  Regulation (EU) No 528/2012 of the European Parliament and of the Council of 22 May 2012 concerning the making available on the market and use of biocidal products (OJ L 167, 27.6.2012, p. 1).
      
      
         
            ANNEX
            In Annex VI to Regulation (EC) No 1272/2008, Table 3 of Part 3 is amended as follows:
            
                        (1)
                     
                     
                        the following entries are inserted:
                        
                                    
                                       Index No
                                    
                                 
                                 
                                    
                                       Chemical name
                                    
                                 
                                 
                                    
                                       EC No
                                    
                                 
                                 
                                    
                                       CAS No
                                    
                                 
                                 
                                    
                                       Classification
                                    
                                 
                                 
                                    
                                       Labelling
                                    
                                 
                                 
                                    
                                       Specific Conc. Limits, M-factors and ATE
                                    
                                 
                                 
                                    
                                       Notes
                                    
                                 
                              
                                    
                                       Hazard Class and Category Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Pictogram, Signal Word Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Suppl. Hazard statement Code(s)
                                    
                                 
                              
                                    ‘007-030-00-3
                                 
                                 
                                    nitric acid …% [C ≤ 70 %]
                                 
                                 
                                    231-714-2
                                 
                                 
                                    7697-37-2.
                                 
                                 
                                    Ox. Liq. 3
                                    Acute Tox. 3
                                    Skin Corr. 1A
                                 
                                 
                                    H272
                                    H331
                                    H314
                                 
                                 
                                    GHS03
                                    GHS06
                                    GHS05
                                    Dgr
                                 
                                 
                                    H272
                                    H331
                                    H314
                                 
                                 
                                    EUH071
                                 
                                 
                                    Ox. Liq. 3; H272: C ≥ 65 %
                                    inhalation: ATE = 2,65 mg/L (vapours)
                                    Skin Corr. 1A; H314: C ≥ 20 %
                                    Skin Corr. 1B; H314: 5 % ≤ C < 20 %
                                 
                                 
                                    B’
                                 
                              
                                    ‘014-048-00-5
                                 
                                 
                                    silicon carbide fibres (with diameter < 3 μm, length > 5 μm and aspect ratio ≥ 3:1)
                                 
                                 
                                    206-991-8
                                 
                                 
                                    409-21-2
                                    308076-74-6
                                 
                                 
                                    Carc. 1B
                                 
                                 
                                    H350i
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H350i’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘014-049-00-0
                                 
                                 
                                    trimethoxyvinylsilane; trimethoxy(vinyl)silane
                                 
                                 
                                    220-449-8
                                 
                                 
                                    2768-02-7
                                 
                                 
                                    Skin Sens. 1B
                                 
                                 
                                    H317
                                 
                                 
                                    GHS07
                                    Wng
                                 
                                 
                                    H317’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘014-050-00-6
                                 
                                 
                                    tris(2-methoxyethoxy)vinylsilane;
                                    6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane
                                 
                                 
                                    213-934-0
                                 
                                 
                                    1067-53-4
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘016-098-00-3
                                 
                                 
                                    dimethyl disulphide
                                 
                                 
                                    210-871-0
                                 
                                 
                                    624-92-0
                                 
                                 
                                    Flam. Liq. 2
                                    Acute Tox. 3
                                    Acute Tox. 3
                                    STOT SE 3
                                    STOT SE 1
                                    Eye Irrit. 2
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H225
                                    H331
                                    H301
                                    H336
                                    H370 (upper respiratory tract, inhalation)
                                    H319
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS02
                                    GHS06
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H225
                                    H331
                                    H301
                                    H336
                                    H370 (upper respiratory tract, inhalation)
                                    H319
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 5 mg/L (vapours)
                                    oral: ATE = 190 mg/kg bw
                                    M = 1
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘029-024-00-X
                                 
                                 
                                    granulated copper;
                                    [particle length: from 0,9 mm to 6,0 mm; particle width: from 0,494 to 0,949 mm]
                                 
                                 
                                    231-159-6
                                 
                                 
                                    7440-50-8
                                 
                                 
                                    Aquatic Chronic 2
                                 
                                 
                                    H411
                                 
                                 
                                    GHS09
                                 
                                 
                                    H411’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘029-025-00-5
                                 
                                 
                                    bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O’)copper;
                                    bis(N-cyclohexyl-diazenium-dioxy)-copper;
                                    [Cu-HDO]
                                 
                                 
                                    239-703-4
                                 
                                 
                                    312600-89-8
                                    15627-09-5
                                 
                                 
                                    Flam. Sol. 1
                                    Acute Tox. 4
                                    STOT RE 2
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H228
                                    H302
                                    H373 (liver)
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS02
                                    GHS07
                                    GHS08
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H228
                                    H302
                                    H373(liver)
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 360 mg/kg bw
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘050-031-00-9
                                 
                                 
                                    dioctyltin dilaurate; [1]
                                    stannane, dioctyl-, bis(coco acyloxy) derivs. [2]
                                 
                                 
                                    222-883-3 [1] 293-901-5 [2]
                                 
                                 
                                    3648-18-8 [1] 91648-39-4 [2]
                                 
                                 
                                    Repr. 1B
                                    STOT RE 1
                                 
                                 
                                    H360D
                                    H372 (immune system)
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360D
                                    H372 (immune system)’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘601-092-00-0
                                 
                                 
                                    dibenzo[def,p]chrysene;
                                    dibenzo[a,l]pyrene
                                 
                                 
                                    205-886-4
                                 
                                 
                                    191-30-0
                                 
                                 
                                    Carc. 1B
                                    Muta. 2
                                 
                                 
                                    H350
                                    H341
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H350
                                    H341
                                 
                                 
                                     
                                 
                                 
                                    Carc. 1B; H350: C ≥ 0,001 %’
                                 
                                 
                                     
                                 
                              
                                    ‘603-237-00-3
                                 
                                 
                                    ipconazole (ISO);
                                    (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol
                                 
                                 
                                    -
                                 
                                 
                                    125225-28-7
                                    115850-69-6
                                    115937-89-8
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 4
                                    STOT RE 2
                                    Aquatic Chronic 1
                                 
                                 
                                    H360D
                                    H302
                                    H373 (eyes, skin, liver)
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360D
                                    H302
                                    H373 (eyes, skin, liver)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 500 mg/kg bw
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘603-238-00-9
                                 
                                 
                                    bis(2-(2-methoxyethoxy)ethyl)ether; tetraglyme
                                 
                                 
                                    205-594-7
                                 
                                 
                                    143-24-8
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘603-239-00-4
                                 
                                 
                                    paclobutrazol (ISO);
                                    (2RS,3RS)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol
                                 
                                 
                                    -
                                 
                                 
                                    76738-62-0
                                 
                                 
                                    Repr. 2
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    Eye Irrit. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361d
                                    H332
                                    H302
                                    H319
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H361d
                                    H332
                                    H302
                                    H319
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 3,13 mg/L (dusts or mists)
                                    oral: ATE = 490 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘603-240-00-X
                                 
                                 
                                    2,2-bis(bromomethyl)propane-1,3-diol
                                 
                                 
                                    221-967-7
                                 
                                 
                                    3296-90-0
                                 
                                 
                                    Carc. 1B
                                    Muta. 1B
                                 
                                 
                                    H350
                                    H340
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H350
                                    H340’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘603-241-00-5
                                 
                                 
                                    geraniol;
                                    (2E)-3,7-dimethylocta-2,6-dien-1-ol
                                 
                                 
                                    203-377-1
                                 
                                 
                                    106-24-1
                                 
                                 
                                    Skin Sens. 1
                                 
                                 
                                    H317
                                 
                                 
                                    GHS07
                                    Wng
                                 
                                 
                                    H317’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘605-041-00-3
                                 
                                 
                                    2-(4-tert-butylbenzyl)propionaldehyde
                                 
                                 
                                    201-289-8
                                 
                                 
                                    80-54-6
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360Fd
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360Fd’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-738-00-8
                                 
                                 
                                    MCPA-thioethyl (ISO);
                                    
                                       S-ethyl (4-chloro-2-methylphenoxy)ethanethioate; S-ethyl 4-chloro-o-tolyloxythioacetate
                                 
                                 
                                    246-831-4
                                 
                                 
                                    25319-90-8
                                 
                                 
                                    Acute Tox. 4
                                    STOT RE. 2
                                    Aquatic Acute 1 Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H373 (liver)
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H302
                                    H373 (liver)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 450 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘607-740-00-9
                                 
                                 
                                    diisooctyl phthalate
                                 
                                 
                                    248-523-5
                                 
                                 
                                    27554-26-3
                                 
                                 
                                    Repr. 1B
                                 
                                 
                                    H360FD
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H360FD’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-741-00-4
                                 
                                 
                                    4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one; flupyradifurone
                                 
                                 
                                    -
                                 
                                 
                                    951659-40-8
                                 
                                 
                                    Acute Tox. 4
                                    STOT RE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H373 (muscle)
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H302
                                    H373 (muscle)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 500 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘607-742-00-X
                                 
                                 
                                    thiencarbazone-methyl (ISO);
                                    methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonylsulfamoyl]-5- methylthiophene-3-carboxylate
                                 
                                 
                                    -
                                 
                                 
                                    317815-83-1
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1000
                                    M = 1000’
                                 
                                 
                                     
                                 
                              
                                    ‘607-743-00-5
                                 
                                 
                                    L-(+)-lactic acid;
                                    (2S)-2-hydroxypropanoic acid
                                 
                                 
                                    201-196-2
                                 
                                 
                                    79-33-4
                                 
                                 
                                    Skin Corr. 1C
                                    Eye Dam. 1
                                 
                                 
                                    H314
                                    H318
                                 
                                 
                                    GHS05
                                    Dgr
                                 
                                 
                                    H314
                                 
                                 
                                    EUH071’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘607-744-00-0
                                 
                                 
                                    2-methoxyethyl acrylate
                                 
                                 
                                    221-499-3
                                 
                                 
                                    3121-61-7
                                 
                                 
                                    Flam. Liq. 3
                                    Muta. 2
                                    Repr. 1B
                                    Acute Tox. 3
                                    Acute Tox. 4
                                    Skin Corr. 1C
                                    Eye Dam. 1
                                    Skin Sens. 1
                                 
                                 
                                    H226
                                    H341
                                    H360FD
                                    H331
                                    H302
                                    H314
                                    H318
                                    H317
                                 
                                 
                                    GHS02
                                    GHS05
                                    GHS06
                                    GHS08
                                    Dgr
                                 
                                 
                                    H226
                                    H341
                                    H360FD
                                    H331
                                    H302
                                    H314
                                    H317
                                 
                                 
                                    EUH071
                                 
                                 
                                    inhalation: ATE = 2,7 mg/L (vapours)
                                    oral: ATE = 404 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘607-745-00-6
                                 
                                 
                                    glyoxylic acid …%
                                 
                                 
                                    206-058-5
                                 
                                 
                                    298-12-4
                                 
                                 
                                    Eye Dam. 1
                                    Skin Sens. 1B
                                 
                                 
                                    H318
                                    H317
                                 
                                 
                                    GHS05
                                    GHS07
                                    Dgr
                                 
                                 
                                    H318
                                    H317
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                    B’
                                 
                              
                                    ‘607-746-00-1
                                 
                                 
                                    sodium N-(hydroxymethyl)glycinate;
                                    [formaldehyde released from sodium N-(hydroxymethyl)glycinate]
                                 
                                 
                                    274-357-8
                                 
                                 
                                    70161-44-3
                                 
                                 
                                    Carc. 1B
                                    Muta. 2
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    STOT SE 3
                                    Skin Irrit. 2
                                    Eye Irrit. 2
                                    Skin Sens. 1
                                 
                                 
                                    H350
                                    H341
                                    H332
                                    H302
                                    H335
                                    H315
                                    H319
                                    H317
                                 
                                 
                                    GHS08
                                    GHS07
                                    Dgr
                                 
                                 
                                    H350
                                    H341
                                    H332
                                    H302
                                    H335
                                    H315
                                    H319
                                    H317
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 3 mg/L (dusts or mists)
                                    oral: ATE = 1100 mg/kg bw
                                 
                                 
                                    8
                                    9’
                                 
                              
                                    ‘611-181-00-6
                                 
                                 
                                    potassium (oxido-NNO-azoxy)cyclohexane;
                                    cyclohexylhydroxydiazene 1-oxide, potassium salt;
                                    [K-HDO]
                                 
                                 
                                    -
                                 
                                 
                                    66603-10-9
                                 
                                 
                                    Flam. Sol. 1
                                    Acute Tox. 3
                                    STOT RE 2
                                    Skin Irrit. 2
                                    Eye Dam. 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H228
                                    H301
                                    H373 (liver)
                                    H315
                                    H318
                                    H411
                                 
                                 
                                    GHS02
                                    GHS06
                                    GHS08
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H228
                                    H301
                                    H373 (liver)
                                    H315
                                    H318
                                    H411
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 136 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘612-294-00-3
                                 
                                 
                                    mecetronium etilsulfate;
                                    
                                       N-ethyl-N,N-dimethylhexadecan-1-aminium ethyl sulfate;
                                    mecetronium ethyl sulphate;
                                    [MES]
                                 
                                 
                                    221-106-5
                                 
                                 
                                    3006-10-8
                                 
                                 
                                    Skin Corr. 1
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H314
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H314
                                    H410
                                 
                                 
                                    EUH071
                                 
                                 
                                    M = 100
                                    M = 1000’
                                 
                                 
                                     
                                 
                              
                                    ‘613-331-00-6
                                 
                                 
                                    (2RS)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol;
                                    mefentrifluconazole
                                 
                                 
                                    -
                                 
                                 
                                    1417782-03-6
                                 
                                 
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘613-332-00-1
                                 
                                 
                                    oxathiapiprolin (ISO);
                                    1-(4-{4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone
                                 
                                 
                                    -
                                 
                                 
                                    1003318-67-9
                                 
                                 
                                    Aquatic Chronic 1
                                 
                                 
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘613-333-00-7
                                 
                                 
                                    pyrithione zinc; (T-4)-bis[1-(hydroxy-.kappa.O)pyridine-2(1H)-thionato-.kappa.S]zinc
                                 
                                 
                                    236-671-3
                                 
                                 
                                    13463-41-7
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 2
                                    Acute Tox. 3
                                    STOT RE 1
                                    Eye Dam. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H360D
                                    H330
                                    H301
                                    H372
                                    H318
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360D
                                    H330
                                    H301
                                    H372
                                    H318
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 0,14 mg/L (dusts or mists)
                                    oral: ATE = 221 mg/kg bw
                                    M = 1000
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘613-334-00-2
                                 
                                 
                                    flurochloridone (ISO);
                                    3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
                                 
                                 
                                    262-661-3
                                 
                                 
                                    61213-25-0
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 4
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H360FD
                                    H302
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360FD
                                    H302
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 500 mg/kg bw
                                    M = 100
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘613-335-00-8
                                 
                                 
                                    4,5-dichloro-2-octyl-2H-isothiazol-3-one; [DCOIT]
                                 
                                 
                                    264-843-8
                                 
                                 
                                    64359-81-5
                                 
                                 
                                    Acute Tox. 2
                                    Acute Tox. 4
                                    Skin Corr. 1
                                    Eye Dam. 1
                                    Skin Sens. 1A
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H330
                                    H302
                                    H314
                                    H318
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H330
                                    H302
                                    H314
                                    H317
                                    H410
                                 
                                 
                                    EUH071
                                 
                                 
                                    inhalation: ATE = 0,16 mg/L (dusts or mists)
                                    oral: ATE = 567 mg/kg bw
                                    Skin Irrit. 2; H315: 0,025 % ≤ C < 5 %
                                    Eye Irrit. 2; H319: 0,025 % ≤ C < 3 %
                                    Skin Sens. 1A; H317: C ≥ 0,0015 %
                                    M = 100
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘613-336-00-3
                                 
                                 
                                    2-methyl-1,2-benzothiazol-3(2H)-one;
                                    [MBIT]
                                 
                                 
                                    -
                                 
                                 
                                    2527-66-4
                                 
                                 
                                    Acute Tox. 4
                                    Acute Tox. 3
                                    Skin Corr. 1C
                                    Eye Dam. 1
                                    Skin Sens. 1A
                                    Aquatic Acute 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H312
                                    H301
                                    H314
                                    H318
                                    H317
                                    H400
                                    H411
                                 
                                 
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H312
                                    H301
                                    H314
                                    H317
                                    H410
                                 
                                 
                                    EUH071
                                 
                                 
                                    dermal: ATE = 1100 mg/kg bw
                                    oral: ATE = 175 mg/kg bw
                                    Skin Sens. 1A; H317: C ≥ 0,0015 %
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘616-228-00-4
                                 
                                 
                                    3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide;
                                    fluxapyroxad
                                 
                                 
                                    -
                                 
                                 
                                    907204-31-3
                                 
                                 
                                    Lact.
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H362
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H362
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘616-230-00-5
                                 
                                 
                                    
                                       N-(hydroxymethyl)acrylamide; methylolacrylamide; [NMA]
                                 
                                 
                                    213-103-2
                                 
                                 
                                    924-42-5
                                 
                                 
                                    Carc. 1B
                                    Muta. 1B
                                    STOT RE 1
                                 
                                 
                                    H350
                                    H340
                                    H372 (peripheral nervous system)
                                 
                                 
                                    GHS08
                                    Dgr
                                 
                                 
                                    H350
                                    H340
                                    H372 (peripheral nervous system)’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘616-231-00-0
                                 
                                 
                                    5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide;
                                    penflufen
                                 
                                 
                                    -
                                 
                                 
                                    494793-67-8
                                 
                                 
                                    Carc. 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘616-232-00-6
                                 
                                 
                                    iprovalicarb (ISO);
                                    isopropyl [(2S)-3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl]carbamate
                                 
                                 
                                    -
                                 
                                 
                                    140923-17-7
                                 
                                 
                                    Carc. 2
                                 
                                 
                                    H351
                                 
                                 
                                    GHS08
                                    Wng
                                 
                                 
                                    H351’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘616-233-00-1
                                 
                                 
                                    silthiofam (ISO);
                                    
                                       N-allyl-4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxamide
                                 
                                 
                                    -
                                 
                                 
                                    175217-20-6
                                 
                                 
                                    STOT RE 2
                                    Aquatic Chronic 2
                                 
                                 
                                    H373
                                    H411
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H373
                                    H411’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘650-057-00-6
                                 
                                 
                                    Margosa, ext. [cold-pressed oil of Azadirachta indica seeds without shells extracted with super-critical carbon dioxide]
                                 
                                 
                                    283-644-7
                                 
                                 
                                    84696-25-3
                                 
                                 
                                    Aquatic Chronic 3
                                 
                                 
                                    H412
                                 
                                 
                                     
                                 
                                 
                                    H412’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                  
                        (2)
                     
                     
                        the entries corresponding to index numbers 007-004-00-1; 014-018-00-1; 015-134-00-5; 015-181-00-1; 050-021-00-4; 050-027-00-7; 082-013-00-1; 603-014-00-0; 603-065-00-9; 605-019-00-3; 607-177-00-9; 607-256-00-8; 607-314-00-2; 609-041-00-4; 609-064-00-X; 613-112-00-5; 613-115-00-1; 613-125-00-6; 613-202-00-4; 613-259-00-5; 616-014-00-0 and 617-006-00-X are replaced by the following entries respectively:
                        
                                    
                                       Index No
                                    
                                 
                                 
                                    
                                       Chemical name
                                    
                                 
                                 
                                    
                                       EC No
                                    
                                 
                                 
                                    
                                       CAS No
                                    
                                 
                                 
                                    
                                       Classification
                                    
                                 
                                 
                                    
                                       Labelling
                                    
                                 
                                 
                                    
                                       Specific Conc. Limits, M-factors and ATE
                                    
                                 
                                 
                                    
                                       Notes
                                    
                                 
                              
                                    
                                       Hazard Class and Category Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Pictogram, Signal Word Code(s)
                                    
                                 
                                 
                                    
                                       Hazard statement Code(s)
                                    
                                 
                                 
                                    
                                       Suppl. Hazard statement Code(s)
                                    
                                 
                              
                                    ‘007-004-00-1
                                 
                                 
                                    nitric acid …% [C > 70 %]
                                 
                                 
                                    231-714-2
                                 
                                 
                                    7697-37-2
                                 
                                 
                                    Ox. Liq. 2
                                    Acute Tox. 1
                                    Skin Corr. 1A
                                 
                                 
                                    H272
                                    H330
                                    H314
                                 
                                 
                                    GHS03
                                    GHS06
                                    GHS05
                                    Dgr
                                 
                                 
                                    H272
                                    H330
                                    H314
                                 
                                 
                                    EUH071
                                 
                                 
                                    Ox. Liq. 2; H272: C ≥ 99 %
                                    Ox. Liq. 3; H272: 70 % ≤ C < 99 %
                                 
                                 
                                    B’
                                 
                              
                                    ‘014-018-00-1
                                 
                                 
                                    octamethylcyclotetrasiloxane;
                                    [D4]
                                 
                                 
                                    209-136-7
                                 
                                 
                                    556-67-2
                                 
                                 
                                    Repr. 2
                                    Aquatic Chronic 1
                                 
                                 
                                    H361f ***
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361f ***
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘015-134-00-5
                                 
                                 
                                    pirimiphos-methyl (ISO);
                                    
                                       O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl phosphorothioate
                                 
                                 
                                    249-528-5
                                 
                                 
                                    29232-93-7
                                 
                                 
                                    Acute Tox. 4
                                    STOT RE 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H302
                                    H372 (nervous system)
                                    H400
                                    H410
                                 
                                 
                                    GHS07
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H302
                                    H372 (nervous system)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1414 mg/kg bw
                                    M = 1000
                                    M = 1000’
                                 
                                 
                                     
                                 
                              
                                    ‘015-181-00-1
                                 
                                 
                                    phosphine
                                 
                                 
                                    232-260-8
                                 
                                 
                                    7803-51-2
                                 
                                 
                                    Flam. Gas 1
                                    Press. Gas
                                    Acute Tox. 1
                                    Skin Corr. 1B
                                    Aquatic Acute 1
                                 
                                 
                                    H220
                                    H330
                                    H314
                                    H400
                                 
                                 
                                    GHS02
                                    GHS04
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H220
                                    H330
                                    H314
                                    H400
                                 
                                 
                                     
                                 
                                 
                                    inhalation:
                                    ATE = 10 ppmV (gases)
                                 
                                 
                                    U’
                                 
                              
                                    ‘050-021-00-4
                                 
                                 
                                    dichlorodioctylstannane
                                 
                                 
                                    222-583-2
                                 
                                 
                                    3542-36-7
                                 
                                 
                                    Repr. 1B
                                    Acute Tox. 2
                                    STOT RE 1
                                    Aquatic Chronic 3
                                 
                                 
                                    H360D
                                    H330
                                    H372 **
                                    H412
                                 
                                 
                                    GHS08
                                    GHS06
                                    Dgr
                                 
                                 
                                    H360D
                                    H330
                                    H372 **
                                    H412
                                 
                                 
                                     
                                 
                                 
                                    Repr. 1B; H360 D: C ≥ 0,03 %
                                    inhalation: ATE = 0,098 mg/L (dusts or mists)’
                                 
                                 
                                     
                                 
                              
                                    ‘050-027-00-7
                                 
                                 
                                    2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE]
                                 
                                 
                                    239-622-4
                                 
                                 
                                    15571-58-1
                                 
                                 
                                    Repr. 1B
                                    STOT RE 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H360D
                                    H372 (immune system)
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360D
                                    H372 (immune system)
                                    H410’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                                    ‘082-013-00-1
                                 
                                 
                                    lead powder; [particle diameter < 1 mm]
                                 
                                 
                                    231-100-4
                                 
                                 
                                    7439-92-1
                                 
                                 
                                    Repr. 1A
                                    Lact.
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H360FD
                                    H362
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H360FD H362
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    Repr. 1A; H360D: C ≥ 0,03 %
                                    M = 1
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘603-014-00-0
                                 
                                 
                                    2-butoxyethanol;
                                    ethylene glycol monobutyl ether
                                 
                                 
                                    203-905-0
                                 
                                 
                                    111-76-2
                                 
                                 
                                    Acute Tox. 4*
                                    Acute Tox. 4
                                    Skin Irrit. 2
                                    Eye Irrit. 2
                                 
                                 
                                    H332
                                    H302
                                    H315
                                    H319
                                 
                                 
                                    GHS07
                                    Wng
                                 
                                 
                                    H332
                                    H302
                                    H315
                                    H319
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1200 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘603-065-00-9
                                 
                                 
                                    
                                       m-bis(2,3-epoxypropoxy)benzene;
                                    resorcinol diglycidyl ether
                                 
                                 
                                    202-987-5
                                 
                                 
                                    101-90-6
                                 
                                 
                                    Carc. 1B
                                    Muta. 2
                                    Acute Tox. 3
                                    Acute Tox. 4
                                    Skin Irrit. 2
                                    Eye Irrit. 2
                                    Skin Sens. 1
                                    Aquatic Chronic 3
                                 
                                 
                                    H350
                                    H341
                                    H311
                                    H302
                                    H315
                                    H319
                                    H317
                                    H412
                                 
                                 
                                    GHS08
                                    GHS06
                                    Dgr
                                 
                                 
                                    H350
                                    H341
                                    H311
                                    H302
                                    H315
                                    H319
                                    H317
                                    H412
                                 
                                 
                                     
                                 
                                 
                                    dermal: ATE = 300 mg/kg bw oral: ATE = 500 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘607-177-00-9
                                 
                                 
                                    tribenuron-methyl (ISO);
                                    methyl 2-[N-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-N-methylcarbamoylsulfamoyl]benzoate
                                 
                                 
                                    401-190-1
                                 
                                 
                                    101200-48-0
                                 
                                 
                                    STOT RE 2
                                    Skin Sens. 1
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H373
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H373
                                    H317
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 100
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘607-256-00-8
                                 
                                 
                                    azoxystrobin (ISO);
                                    methyl (E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl}-3-methoxyacrylate
                                 
                                 
                                    -
                                 
                                 
                                    131860-33-8
                                 
                                 
                                    Acute Tox. 3
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H331
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS09
                                    Dgr
                                 
                                 
                                    H331
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation:
                                    ATE = 0,7 mg/L (dusts or mists)
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘607-314-00-2
                                 
                                 
                                    ethofumesate (ISO);
                                    (RS)-2-ethoxy-2,3-dihydro-3,3-dimethylbenzofuran-5-yl methanesulfonate
                                 
                                 
                                    247-525-3
                                 
                                 
                                    26225-79-6
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘609-041-00-4
                                 
                                 
                                    2,4-dinitrophenol
                                 
                                 
                                    200-087-7
                                 
                                 
                                    51-28-5
                                 
                                 
                                    Acute Tox. 3 *
                                    Acute Tox. 3
                                    Acute Tox. 2
                                    STOT RE 1
                                    Aquatic Acute 1
                                 
                                 
                                    H331
                                    H311
                                    H300
                                    H372
                                    H400
                                 
                                 
                                    GHS06
                                    GHS08
                                    GHS09
                                    Dgr
                                 
                                 
                                    H331
                                    H311
                                    H300
                                    H372
                                    H400
                                 
                                 
                                     
                                 
                                 
                                    dermal: ATE = 300 mg/kg bw oral: ATE = 30 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘609-064-00-X
                                 
                                 
                                    mesotrione (ISO);
                                    2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione
                                 
                                 
                                    -
                                 
                                 
                                    104206-82-8
                                 
                                 
                                    Repr. 2
                                    STOT RE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H361d
                                    H373 (eyes, nervous system)
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H361d
                                    H373 (eyes, nervous system)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘613-112-00-5
                                 
                                 
                                    octhilinone (ISO);
                                    2-octyl-2H-isothiazol-3-one; [OIT]
                                 
                                 
                                    247-761-7
                                 
                                 
                                    26530-20-1
                                 
                                 
                                    Acute Tox. 2
                                    Acute Tox. 3
                                    Acute Tox. 3
                                    Skin Corr. 1
                                    Eye Dam. 1
                                    Skin Sens. 1A
                                    Aquatic Acute 1 Aquatic Chronic 1
                                 
                                 
                                    H330
                                    H311
                                    H301
                                    H314
                                    H318
                                    H317
                                    H400
                                    H410
                                 
                                 
                                    GHS06
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H330
                                    H311
                                    H301
                                    H314
                                    H317
                                    H410
                                 
                                 
                                    EUH071
                                 
                                 
                                    inhalation: ATE = 0,27 mg/L (dusts or mists)
                                    dermal: ATE = 311 mg/kg bw oral: ATE = 125 mg/kg bw
                                    Skin Sens. 1A; H317: C ≥ 0,0015 %
                                    M = 100
                                    M = 100’
                                 
                                 
                                     
                                 
                              
                                    ‘613-115-00-1
                                 
                                 
                                    hymexazol (ISO);
                                    3-hydroxy-5-methylisoxazole
                                 
                                 
                                    233-000-6
                                 
                                 
                                    10004-44-1
                                 
                                 
                                    Repr. 2
                                    Acute Tox. 4
                                    Eye Dam. 1
                                    Skin Sens. 1
                                    Aquatic Chronic 2
                                 
                                 
                                    H361d
                                    H302
                                    H318
                                    H317
                                    H411
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS05
                                    GHS09
                                    Dgr
                                 
                                 
                                    H361d
                                    H302
                                    H318
                                    H317
                                    H411
                                 
                                 
                                     
                                 
                                 
                                    oral: ATE = 1600 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘613-125-00-6
                                 
                                 
                                    hexythiazox (ISO);
                                    
                                       trans-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-3-thiazolidine-carboxamide
                                 
                                 
                                    -
                                 
                                 
                                    78587-05-0
                                 
                                 
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H400
                                    H410
                                 
                                 
                                    GHS09
                                    Wng
                                 
                                 
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘613-202-00-4
                                 
                                 
                                    pymetrozine (ISO);
                                    (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one
                                 
                                 
                                    -
                                 
                                 
                                    123312-89-0
                                 
                                 
                                    Carc. 2
                                    Repr. 2
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H361fd
                                    H410
                                 
                                 
                                    GHS08
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H361fd
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    M = 1’
                                 
                                 
                                     
                                 
                              
                                    ‘613-259-00-5
                                 
                                 
                                    imiprothrin (ISO);
                                    reaction mass of: [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-cis-chrysanthemate; [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-trans-chrysanthemate
                                 
                                 
                                    428-790-6
                                 
                                 
                                    72963-72-5
                                 
                                 
                                    Carc. 2
                                    Acute Tox. 4
                                    Acute Tox. 4
                                    STOT SE 2
                                    Aquatic Acute 1
                                    Aquatic Chronic 1
                                 
                                 
                                    H351
                                    H332
                                    H302
                                    H371 (nervous system; oral, inhalation)
                                    H400
                                    H410
                                 
                                 
                                    GHS08
                                    GHS07
                                    GHS09
                                    Wng
                                 
                                 
                                    H351
                                    H332
                                    H302
                                    H371 (nervous system; oral, inhalation)
                                    H410
                                 
                                 
                                     
                                 
                                 
                                    inhalation: ATE = 1,4 mg/L (dusts or mists)
                                    oral: ATE = 550 mg/kg bw
                                    M = 10
                                    M = 10’
                                 
                                 
                                     
                                 
                              
                                    ‘616-014-00-0
                                 
                                 
                                    butanone oxime; ethyl methyl ketoxime; ethyl methyl ketone oxime
                                 
                                 
                                    202-496-6
                                 
                                 
                                    96-29-7
                                 
                                 
                                    Carc. 1B
                                    Acute Tox. 4
                                    Acute Tox. 3
                                    STOT SE 3
                                    STOT SE 1
                                    STOT RE 2
                                    Skin Irrit. 2
                                    Eye Dam. 1
                                    Skin Sens. 1
                                 
                                 
                                    H350
                                    H312
                                    H301
                                    H336
                                    H370 (upper respiratory tract)
                                    H373 (blood system)
                                    H315
                                    H318
                                    H317
                                 
                                 
                                    GHS08
                                    GHS06
                                    GHS05
                                    Dgr
                                 
                                 
                                    H350
                                    H312
                                    H301
                                    H336
                                    H370 (upper respiratory tract)
                                    H373 (blood system)
                                    H315
                                    H318
                                    H317
                                 
                                 
                                     
                                 
                                 
                                    dermal: ATE = 1100 mg/kg bw oral: ATE = 100 mg/kg bw’
                                 
                                 
                                     
                                 
                              
                                    ‘617-006-00-X
                                 
                                 
                                    bis(α,α-dimethylbenzyl) peroxide
                                 
                                 
                                    201-279-3
                                 
                                 
                                    80-43-3
                                 
                                 
                                    Org. Perox. F
                                    Repr. 1B
                                    Skin Irrit. 2
                                    Eye Irrit. 2
                                    Aquatic Chronic 2
                                 
                                 
                                    H242
                                    H360D
                                    H315
                                    H319
                                    H411
                                 
                                 
                                    GHS02
                                    GHS08
                                    GHS07
                                    GHS09
                                    Dgr
                                 
                                 
                                    H242
                                    H360D
                                    H315
                                    H319
                                    H411’
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                                 
                                     
                                 
                              
                  
                        (3)
                     
                     
                        the entries corresponding to index numbers 601-064-00-8 and 607-693-00-4 are deleted.