Ex hibit 31.1 CERTIFICATION PURSUANT TO EXCHANGE ACT RULE 13a-14 (a) /15d-14 (a) , AS ADOPTED PURSUANT TO SECTION -OXLEY ACT OF 2002 I, Ramin (Ron) Najafi, certify that: 1. I have reviewed this Form 10-K/A of Nova Bay Pharmaceuticals, Inc.; and 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. Date: April 13, 2015 /s/ Ramin (Ron) Najafi Ramin (Ron) Najafi, Ph D. Chairman and Chief Executive Officer (principal executive officer)