Patent Abstract:
A diagnostic apparatus including a catheter carrying a first ultrasonic transducer adapted to be inserted into a patient, a second ultrasonic transducer adapted to be placed in spaced relation to the catheter at either a known location within the patient&#39;s body or a known location associated with the exterior surface of the patient&#39;s body, a processing device operably connected to at least the first ultrasonic transducer, and a display device.

Full Description:
CROSS REFERENCE TO RELATED APPLICATIONS 
     This application is a continuation of application Ser. No. 08/938,406, filed Sep. 26, 1997 now U.S. Pat. No. 6,027,451. 
    
    
     BACKGROUND OF THE INVENTION 
     1. Field of Invention 
     The present invention relates generally to a device for diagnosing the body with ultrasonic waves and, more particularly, to an invasive ultrasound device. 
     2. Description of the Related Art 
     Non-invasive ultrasound techniques have been used for many years to produced detailed images of bodily structures. In a non-invasive procedure, a transducer is placed on the surface of the patient&#39;s body. An image is generated by producing an ultrasound signal with the transducer, receiving the reflected portion of the ultrasound signal with the transducer, and then transmitting a corresponding signal to a device which includes imaging circuitry and a display. In echocardiography, for example, a transducer is placed on the patient&#39;s chest and an image of the heart is produced. 
     In recent years, invasive ultrasound techniques have been developed. Here, a miniature ultrasound transducer is mounted on a catheter that is directed into the bodily structure of interest. The image shown on the display is a cross-section (or “slice”) of that structure. One invasive ultrasound technique is intracardiac echocardiography. Here, a transducer is carried by a catheter into the patient&#39;s heart and the image shown on the display is a cross-section of the heart. 
     The inventor herein has determined that one disadvantage of conventional invasive ultrasound techniques is that the angular orientation of the displayed image is not fixed relative to an anatomical direction. Moreover, the image will often rotate as the transducer carrying catheter rotates relative to the patient. This rotation can be caused by operator handling of the catheter and the motion associated with cardiac and respiratory cycles. Despite the fact that physicians are familiar with the large scale anatomy of the heart and other organs, as well as the associated vascular structures, it is often difficult for them to place the displayed cross-sections within the context of the organ of interest. The physician must rely on his or her knowledge of bodily structures to first recognize the portion of the body being imaged. Once that task is completed, the physician must infer the rotational orientation of the image based on the typical orientation of that structure relative to the other portions of the patient&#39;s body. 
     SUMMARY OF THE INVENTION 
     Accordingly, the general object of the present invention is to provide a diagnostic method and apparatus which avoids, for practical purposes, the aforementioned problems. In particular, one object of the present invention is to provide a diagnostic method and apparatus which allows the physician to readily determine the anatomical orientation of the displayed image. 
     In order to accomplish at least some of these and other objectives, a diagnostic apparatus in accordance with one embodiment of the present invention includes a catheter carrying a first ultrasonic transducer adapted to be inserted into a patient, a second ultrasonic transducer adapted to be placed in spaced relation to the catheter at either a known location within the patient&#39;s body or a known location associated with the exterior surface of the patient&#39;s body, a processing device operably connected to at least the first ultrasonic transducer, and a display device. The first and second transducers each produce ultrasonic waves that will propagate through the adjacent bodily structure. The waves generated by the first transducer ultimately produce an image of the bodily structure of interest, while the waves generated by the second transducer establish a reference point. 
     The present invention provides a number of advantages over the prior art. For example, in accordance with one embodiment of the invention, the displayed image may include two portions—the first being representative of the bodily structure of interest and the second being be representative of the location of the second transducer. Because the location of the second transducer is a known location, such as anterior side of the patient, the displayed image will immediately convey the anatomical orientation of the image to the physician. In accordance with another embodiment of the invention, the displayed image may be automatically oriented in a predetermined anatomical orientation. For example, the image may be displayed such that the anterior side of the image is always at the top of the display. Here again, the displayed image will immediately convey the anatomical orientation of the image. Accordingly, the present invention solves the aforementioned problem in the art. 
     The present invention is particularly useful in intracardiac, intravascular and endoluminal imaging applications. The present invention may, however, be practiced in conjunction with imaging applications concerning other echogenic tissue, such as liver, parenchyma, bile duct, urinary bladder and intracranial tissue. In other words, the present invention may be practiced in any echogenic portion of the body that will allow passage of a catheter. Also, in addition to imaging, the present invention may also be practiced with a wide variety of therapeutic applications. For example, the imaging features of the present invention may be used to help physicians guide various catheter-based tools, such as ablation, laser, cutting and occluding tools, to their intended locations. 
     The above described and many other features and attendant advantages of the present invention will become apparent as the invention becomes better understood by reference to the following detailed description when considered in conjunction with the accompanying drawings. 
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS 
     Detailed description of preferred embodiments of the invention will be made with reference to the accompanying drawings. 
     FIG. 1 is a perspective view of a diagnostic apparatus in accordance with a preferred embodiment of the present invention. 
     FIG. 2 is an enlarged view of a portion of the apparatus shown in FIG.  1 . 
     FIG. 3 is a block diagram of a diagnostic apparatus in accordance with the present invention. 
     FIG. 4 is an illustration of an exemplary procedure which may be performed in accordance with the present invention. 
     FIG. 5 is a plan view of a displayed image in accordance with one embodiment of the present invention. 
     FIG. 6 is a plan view of a displayed image in accordance with another embodiment of the present invention. 
     FIG. 7 is a flow chart in accordance with one embodiment of the present invention. 
     FIG. 8 is a plan view of a displayed image in accordance with another embodiment of the present invention. 
     FIG. 9 is a perspective view of a hand held transducerdevice. 
     FIG. 10 a perspective view of a diagnostic apparatus in accordance with another preferred embodiment of the present invention. 
     FIG. 11 a perspective view of a diagnostic apparatus in accordance with still another preferred embodiment of the present invention. 
    
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
     The following is a detailed description of the best presently known modes of carrying out the invention. This description is not to be taken in a limiting sense, but is made merely for the purpose of illustrating the general principles of the invention. The scope of the invention is defined by the appended claims. 
     As illustrated for example in FIGS. 1-3, a diagnostic apparatus  10  in accordance with a preferred embodiment of the present invention includes a catheter  12  having an ultrasonic transducer  14  associated therewith and an ultrasonic transducer  16  that may be secured to the exterior surface of the patient&#39;s body. The transducer  16 , which acts a reference transducer, may instead be associated with a catheter so that it too may be inserted into the patient&#39;s body, or associated with a handle so that the physician can easily move the reference transducer  16  during examination. These aspects of the invention are discussed below with reference to FIGS. 9 and 11. The exemplary catheter  12  includes a handle  18 , a steering knob  20 , and a guide tube assembly  22 . Such a catheter is disclosed in commonly assigned U.S. Pat. No. 5,456,664. The present invention may, however, be practiced with any catheter capable of positioning the transducer  14  at the desired location within the patient&#39;s body. The transducer  14  is located at the tip  24  of the guide tube assembly  22 . With respect to the transducer itself, suitable ultrasonic transducers include, but are not limited to, phased array transducers, mechanical transducers, dynamic array transducers, offset stereoscopic imaging transducers, and multidimensional imaging transducers. 
     In the exemplary embodiment shown in FIGS. 1-3, the ultrasonic transducers  14  and  16  are connected to a control and display device  26  by electrical leads  28  and  30 . The control and display device may be a unitary structure, as shown, or separated into independent control and display devices. The exemplary control and display device  26  includes a display  32 , a control panel  34 , and a printer  36  which may be used to produce a printed version  38  of the image  40  displayed on the display. The control and display device  26  also includes an electronic controller  42 , such as a microprocessor-based controller, control circuits  44  and  46  which cause the transducers  14  and  16  to vibrate and produce ultrasound waves, and transceiver circuits  48  and  50  which receive and transmit signals via the electrical leads  28  and  30 . The display  32  is driven by imaging circuitry  52 . 
     One example of an imaging procedure in accordance with the present invention is illustrated in FIG.  4 . Here, the catheter guide tube  22  is inserted into the patient  54  such that the transducer supporting tip  24  enters the patient&#39;s heart  56 . The reference transducer  16  is secured to the patient&#39;s chest  58  (i.e. on the anterior portion of the patient&#39;s body) with adhesive tape or other suitable means. The catheter tip  24  and transducer  14  can, of course, be inserted into other portions of the patient&#39;s body and the reference transducer  16  repositioned accordingly. 
     During one mode of operation, the control and display device  26  causes transducers  14  and  16  to produce suitable ultrasonic waves that will propagate through the adjacent bodily structure. A portion of the waves (or signals) generated by the catheter-based transducer  14  will be reflected back from the bodily structure and impinge on the catheter-based transducer. The waves generated by the reference transducer  16  also impinge the catheter-based transducer  14 . An electrical signal corresponding to the impinging waves is generated by the transducer  14  then and transmitted to the controller  42  via the transceiver circuit  48 . A corresponding image is then generated by the imaging circuitry  52  and displayed on the display  32 . 
     As shown by way of example in FIG. 5, the image  40  presented on the display  32  has two significant portions. The first image portion  60  is a visual representation of a cross-section of the bodily structure of interest. In accordance with the exemplary procedure shown in FIG. 4, the first image portion  60  is a cross-section of the patient&#39;s heart. The second image portion  62  is indicative of the direction of the signals received by the catheter-based transducer  14  from the reference transducer  16 . Because the reference transducer  16  is in a known location (here, the anterior side of the patient), the image  40  generated in accordance with the present invention will immediately convey its anatomical orientation to the reviewing physician. 
     The second image portion  62  may be continuously displayed, displayed intermittently, or displayed only upon demand. Continuous and intermittent display may be accomplished by simply supplying a continuous and intermittent signals to the reference transducer  16 . On demand display may be provided through the use of a foot switch  63 , a button on the control panel  34 , or other suitable switching devices that allow the physician to selectively actuate the reference transducer  16 . 
     The present invention may also be operated in various auto-orientation modes in which the image is displayed in a predetermined anatomical orientation. Referring more specifically to FIG. 6, the image  40  may be oriented such that the anterior portion of the patient&#39;s body is always at the top of the display  32 . Such auto-orientation may be accomplished in a variety of manners. For example, the location of the reference transducer  16 , i.e. anterior or posterior, and the desired orientation of the image  40  may be input into the controller  42  via the control panel  34 . Once the controller has this information, the image may be analyzed and, if necessary, reoriented prior to display. The analysis is accomplished through conventional image analysis techniques performed by the imaging circuit  52  and controller  42 . 
     In another embodiment of the invention, the second portion  62  of the image  40  (which corresponds to the reference transducer  16 ) will always be displayed on the same portion of the display, such as at the top portion, regardless of the anatomical location of the transducer. 
     As shown by way of example in FIG. 7, a suitable program for performing the auto-orientation functions operates as follows. First, in steps  100 - 120 , the signals from the catheter-based transducer  14  are received, an image is created by the imaging circuit  52  and, prior to display, the image is analyzed by controller  42 . The step of analyzing the image consists primarily of isolating the second image portion  62  and determining its angular orientation. In step  130 , the controller determines whether the second image portion  62  is oriented in a predetermined orientation. The predetermined orientation of the second image portion  62  is the orientation which corresponds to an image  40  displayed in the orientation desired by the physician or a preset orientation. For example, if the reference transducer  16  is placed on the anterior side of the patient and the desired image orientation is one where the anterior side is at the top of the display  32 , then the predetermined orientation of the second image portion  62  would be one where the second image portion is aligned with the top portion of cross hair  64 , as shown in FIG.  6 . The image is then displayed on the display  32 . [Step  140 .] 
     When the second image portion  62  is not in the predetermined orientation, as is the case in FIG. 5, then an offset angle  66  (or correction amount) is calculated and the image  40  is rotated accordingly (steps  150  and  160 ) prior to display of the image. This process can, if desired, continue as long as signals are being received from the catheter-based transducer  14 . [Steps  170  and  180 .] As illustrated in FIG. 8, the second image portion  62 , may be filtered out of the image  40  prior to display when the present invention is operating in an auto-orientation mode. Nevertheless, the automatic orientation of the image will continue as long as desired. 
     In accordance with another exemplary embodiment of the present invention, and as shown by way of example in FIG. 9, a reference transducer  68  may be incorporated into a device  70  which has a handle  72 . This allows the physician to move the reference transducer from one location to another during an examination when, for example, the patient has to be moved. The above-described auto-orientation features can, of course, be used to either reorient the image or maintain the image in the same orientation when the reference transducer is moved. 
     Turning to FIG. 10, a diagnostic apparatus  74  in accordance with another preferred embodiment of the present invention includes a catheter  76  having an ultrasonic transducer associated therewith. The catheter-based transducer is electrically coupled to a display and control device  78  which operates in substantially the same manner as the display and control device  26  shown in FIG.  1 . Here, however, a plurality of reference transducers  80  are provided. The reference transducers  80  may be positioned at different portions of the patient&#39;s body so as to provide a number of reference images similar to the image portion  62  shown in FIGS. 5 and 6. Alternatively, a switching device (such as a foot pedal or control knob) may be employed to allow the physician to selectively activate the reference transducers one at a time. Thus, the physician will be able switch between various known anatomical reference points. 
     As shown by way of example in FIG. 11, a diagnostic apparatus  82  in accordance with another embodiment of the present invention includes a pair of catheters  84  and  86 , each of which includes an ultrasound transducer. Both catheters are electrically coupled to a display and control device  88  which operates in substantially the same manner as the display and control device  26  shown in FIG.  1 . The first catheter  86  functions as the imaging catheter. The transducer in the second catheter  86  acts as the reference transducer. Incorporating the reference transducer into a catheter allows the physician to place the anatomical reference point within the patient&#39;s body. The apparatus shown in FIG. 11 may, alternatively, include a plurality of reference catheters which will provide a plurality of reference points within the patient&#39; body. Here too, a switching device may be employed so that the physician can selectively activate the reference transducers. 
     Although the present invention has been described in terms of the preferred embodiment above, numerous modifications and/or additions to the above-described preferred embodiments would be readily apparent to one skilled in the art. It is intended that the scope of the present invention extends to all such modifications and/or additions and that the scope of the present invention is limited solely by the claims set forth below.

Technology Classification (CPC): 0