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oas_paired_human_sars_cov_2

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100K<n<1M

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train · 513k rows

sequence_alignment_aa_heavy stringlengths 110 157	cdr1_start_heavy int64 133 563	cdr1_end_heavy int64 156 586	cdr2_start_heavy float64 208 638	cdr2_end_heavy float64 231 667	cdr3_start_heavy float64 346 782	cdr3_end_heavy float64 372 835	sequence_alignment_aa_light stringlengths 100 126	cdr1_start_light int64 133 822	cdr1_end_light int64 152 848	cdr2_start_light float64 204 900 ⌀	cdr2_end_light float64 212 908 ⌀	cdr3_start_light float64 321 1.02k	cdr3_end_light float64 350 1.05k
QVQLQESGPGLVKPSGTLSLTCTVSGHSISRSHWWSWVRQAPGKGLEWIGEIYHSGTTNYNPSLKSRVTISVDKSNNQFSLTLNSMTAADTALYYCARGREGNWNYILDSWGRGTLVTVSS	168	194	246	266	381	422	EVVLTQSPATLSLSPGERATLSCRASQSIGNYLAWYQQKPGQAPRLLIYDASNRATAVPARFSGGGSGTDFTLSISSLEPEDFAIYYCLHRSNWLTFGGGTKVEIK	175	192	244	252	361	384
QVQLVESGGGVVQPGRSLTLSCAASGFTFSSYGLHWVRQAPGKGLEWVANIWYDGANKYYGDSVKGRFTISRDNSRNTLYLQMNSLTAEDTAVYYCARWIEYGSGKDAFDVWGQGTMVIVSS	213	236	288	311	426	470	DIQLTQSPSSLSASVGDRVTITCRASQYINNLLNWYQQKPGKAPKVLIYGASNLQSGVPSRFSGSGSGTDFTLTISGLQLEDFATYFCQQSYSTWTFGQGTKVEIK	175	192	244	252	361	384
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDANSHGLGYWGQGTLVTVSS	192	215	267	287	402	434	DIQMTQSPSSLSASVGDRVTITCRASQGISNYLAWFQQKPGKAPKSLIYAASSLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYNSYPWTFGQGTKVEIK	172	189	241	249	358	384
QVTLRESGPALVKPTQTLTLTCTFSGFSLSTSGMCVSWIRQPPGKALEWLALIDWDDDKYYSTSLKTRLTISKDTSKNQVVLTMTNMDPVDTATYYCARQYYYDSSGYYYDWYFDLWGRGTLVTVSS	152	181	233	253	368	424	QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL	175	201	253	261	370	399
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARELLWELEEADWFDPWGQGTLVTVSS	190	219	271	291	406	453	DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYWRTFGQGTKVEIK	171	188	240	248	357	383
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDYYDSSGPDYWGQGTLVTVSS	213	236	288	311	426	461	DVVMTQSPLSLPVTLGQPASISCRSSQSLVYSDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQGTHWPHTFGQGTKLEIK	192	224	276	284	393	419
QVQLQESGPGLVKPSETLSLTCTVSGGSFRSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASTSAGYWGQGTLVTVSS	207	230	282	302	417	437	DIQMTQSPSSLSASVGDSVTITCRASQSIRNYLSWYHHKPGQAPKLLIYGASSLQSGVPSRFSGSGSGTDFTLTISSLQAEDFATYYCQQSDSLPWTFGQGTKVDIK	179	196	248	256	365	391
DVQLLESGGGLVQPGGSLRLSCAASGFTFSNYALSWVRQAPGKGLEWVSSIIGSGGVTSYADSVRGRFTISRDNSKNTLYLQMDSLRTEDTAVYYCARDGGTPQYNLNYFYWGQGTLVTVSS	212	235	287	310	425	469	EIVLTQSPDTLSLSPGERATLSCRASQTITNNYLAWYRQKPGQAPRLLIYAASYRAAGIPDRFSGGGSGTDFTLTISRLEPEDFAMFYCHQYGTSPTFGQGTKVEIK	175	195	247	255	364	387
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPLYYDFWSGPTLGDYWGQGTLVTVSS	213	236	288	317	432	485	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPYTFGQGTKLEIK	186	203	255	263	372	401
DVQLVESGGGLAQPGGSLRLSCAASGFTFSSYWMTWVRRAPGKGLEWVANINGNGKEYVESVKGRFTISRDNAKNSLFLQMNSLRVEDTAVYYCARDPYDHDSGSYGAFDVWGQGTPVTVSS	212	235	287	304	419	469	DVVMTQSPLSLPVTLGQPASISCRSSQSLVYKDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGIYYCMQGTQWPYTFGQGTKLEIK	200	232	284	292	401	427
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTAEGSFDYWGQGTLVTVSS	213	236	288	317	432	458	SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSGVFGGGTKLTVL	294	311	363	371	480	503
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIHISGSTNYNPSLKSRVTMSVDTSRNQFSLKLSSVTAADTAVYYCAASTGGYSSSWAEYYFGYWGQGTLVTVSS	168	197	249	269	384	437	DIVMTQSPDSLAVSLGERATINCKSSQNVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPYTFGQGTKLEIK	169	204	256	264	373	399
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHQSPYYGSVAFDYWGQGTLVTVSS	157	186	238	258	373	414	QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAYVFGTGTKVTVL	169	192	244	252	361	393
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKFFAPVAYYYDSSEQGDYYGMDVWGQGTTVTVSS	212	235	287	310	425	496	AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPLTFGGGTKVEIK	172	189	241	249	358	384
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDVWYYDSSGYNDYWGQGTLVTVSS	212	235	287	310	425	469	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPWGAFGPGTKVDIK	186	203	255	263	372	401
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGRINPNSGSTNYAQKFQGRVTMTSDTSTSTVYMELSSLRSEDTAVYYCARPALAYSINWSSLDWFDPWGQGTLVTVSS	191	214	266	289	404	460	DIQMTQSPATLSAFVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIQKASSLESGVPSRFSGSGSGTEFTLTISRLQPDDFATYYCQQYNTYSLTFGGGTKVEIK	172	189	241	249	358	384
EVQLVESGGGFVHPGESLRLSCVASGFTFRPFWMNWVRQVPGKGLEWVATIGEDESRTWYLDSVKGRFTISRDNTKNSLYLQMDNLKAEDSAIYYCTRDPDTSSKVDFWGQGTLVTVSS	212	235	287	310	425	460	DVVMTQSPLSLPVTLGQPASISCRSSLSLVYSDGNAYLSWFQQRPGQSPRRLIYEVSKRDSGVPDRFSGSGSGTDFTLRISRVEAEDVGYYYCMQGTYRPPTFGQGTRLEIK	169	201	253	261	370	396
DVKLLESGGSVVQPGGSLRLSCAASGFSFSSYAMSWVRQAPGRGLEWVSTITNSGTNTYFTDSVKGRFAISRDNSRETLYLQLNSLRAEDTAVYYCAKTWWGGTNENSVWFDPWGQGTLVTVSS	212	235	287	310	425	475	EIVLTQSPATLSLSPGERATLSCRASQSVSSFLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSSWPPITFGQGTRLEIK	186	203	255	263	372	401
EVQLVESGGGLVQPGGSLRLSCAASGFTFSGYSMNWVRQAPGKGLEWVSYISSGGSPIHYADSVKGRFTISRDNANNSLYLQMNSLRDEDTAVYYCARDYDSSGRAFDYWGQGTLVTVSS	212	235	287	310	425	463	QSVLTQPPSVSAAPGQKVTISCSGSRSNMGIHYVSWYQQLPGTAPQLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSGVVFGGGTKLTVL	169	192	244	252	361	393
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCATGGSYGYYYGMDVWGQGTTVTVSS	213	236	288	311	426	467	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSLWTFGQGTKVEIK	223	243	295	303	412	438
EVQLVQSGAEVKKPGESLKISCKGSGYIFTNYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTMSADKSVSTAYLQWSSLKASDTAMYYCARHGGHCNGGSCSRLPPGSYAMDGWGQGTTVTVSS	192	215	267	290	405	476	DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQAPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPYAFGQGTKLEIK	174	206	258	266	375	401
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRDHPEWELRVSFDYWGQGTLVTVSS	213	236	288	317	432	476	DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNLPQTFGGGTKVEIK	176	193	245	253	362	388
EVQLVESGGGLVQPGGSLKLSCAASGFTFSGSAMHWVRQASGKGLEWVGRIRSKANSYATAYAASVKGRFTISRDDSKNTAYLQMNSLKTEDTAVYYCTRGLIYDSSGSPFDYWGQGTLVTVSS	213	236	288	317	432	476	QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGAVVFGGGTKLTVL	167	193	245	253	362	388
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHRPLLWFGEASGRWFDPWGQGTLVTVSS	157	186	238	258	373	426	DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQANSFPFTFGPGTKVDIK	172	189	241	249	358	384
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAINWVRQAPGQGLEWMGGIIPVFDTTNYAQKFQGRVTITADKSTTTAYMELSSLRSEDAAMYYCARAADRGTYYNYYGMDVWGQGTTVTVSS	181	204	256	279	394	444	EIVLTQSPGSLSLSPGERATLSCRASQSVSRNYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTINRLEPEDFAVYHCQQYGGLPWTFGQGTKLEIK	183	203	255	263	372	398
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGGELSLIYYYYGMDVWGQGTTVTVSS	168	197	249	269	384	434	SSELTQDPAVSVALGQTVRITCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNHLEVFGTGTKVTVL	173	190	242	250	359	394
QVQLQESGPGLVKPSETLSLTCTVSGGSVSSSNYYWTWLRQSPGKGLEWIGYVYYTGTTNYNPSLETRVIISVDTSKNQFSLRLNSVTAADTAVYYCARDEGLSGPRDGGFDPWGQGTLVTVSS	170	199	251	271	386	433	EIVMTQTPLSSPVTLGQPASISCRSSQSLLHSDGNTYLSWLQQRPGQPPRLLIYKISNRFSGVPDRFSGSGAGTDFTLKISRVEAEDVGVYYCMQARQFPYTFGQGTKLEIK	169	201	253	261	370	396
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARDPQWLARFDYWGQGTLVTVSS	213	236	288	311	426	461	QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGRVVFGGGTKLTVL	180	203	255	263	372	407
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPSKNCGGDCYSYYYYYYMDVWGKGTTVTVSS	213	236	288	317	432	500	DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPKTFGQGTKVEIK	172	189	241	249	358	384
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYGISWVRQAPGQGLEWMGWISAYNGNTNYAQKLQGRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARTRLAAYYYYGMDVWGQGTTVTVSS	187	210	262	285	400	444	DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTLWTFGQGTKVEIK	174	206	258	266	375	401
QVQLQESGPGLVKPSGTLSLTCAVSGGSISSNNWWNWVRQPPGKGLEWIGEIYHTGRTNYNPSLKSRVTISVDKSKNQFSLRLSSVTAADTAVYYCARGGGPYFDYWGQGTLVTVSS	172	198	250	270	385	414	EIVLTQSPGTLSLSPGERATLSCRASQSVISDYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSIMYTFGQGTKLEIK	175	195	247	255	364	393
EVQLAESGGGLVQPGGSLRLSCAASGFTFSNYWMNWVRQAPGKGLEWVANIKQDGNTIYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKGGLAPGDYWGQGTLVTVSS	212	235	287	310	425	454	QSVLTQPPSASGTPGQRVTISCSGSNSNIGNNPVNWYQHLPGTAPKLLIYTNNERPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDGSLSGYIFGTGTKVTVL	180	203	255	263	372	404
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSRTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTGVYYCTTHYYDRSGYYPGYFHHWGQGTLVTVSS	213	236	288	317	432	482	DIVMTQSPDSLAVSLGERATINCKSGHSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSPPLTFGGGTKVEIK	169	204	256	264	373	399
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGIANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCASDPQSHYDSSGYYHWGQGTLVTVSS	184	207	259	282	397	441	DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTRITFGQGTRLEIK	174	191	243	251	360	386
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHFNYYDSSGYWTPGRGYFDYWGQGTLVTVSS	153	182	234	254	369	431	QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL	175	201	253	261	370	399
EVRLAESGCSLVQPGGSLSLSCAASGFSLSGYWMHWVRRVPGKGLVWVARISSDGSSTEYADAVKGRFTISRDNAKNTLFLQMNSLRAEDTAVYHCTRGGSVDVIRGVFDSWGQGALVTVSS	201	224	276	299	414	458	DIVMTQSPDSMAVSLGERATINCKSSQSVLYSPNNKNDLTWYQHKPGQPPRLLIYWASTRASGVPDRFSGSGSGTDFTLTISNLQAEDGAIYYCQQHKSDPYTFGQGTKLEIK	169	204	256	264	373	399
EVQLAEAGGGLVQPGGSRRLSCAASGFTFGSYWVSWVRQAPGKGLEWVANINQDGSQKHFVDSVKGRFTISRDSAKNSVYLQIDSLRAEDTALYYCAVDSSGSYGWDSWGQGTLVTVSS	212	235	287	310	425	460	DIQMTQSPSSLSASVGDRVTITCRASQSITRYLNWYQQKPGKAPKLLIYGTSSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSDSVPRTFGQGTKVEIK	175	192	244	252	361	387
EVQLVESGGGLVQPGGSLRLSCAASGFTFSTYWMSWVRQAPGKGLEWVANIKQDESEKYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSTYCTSTSCYHYYYYGMDVWGQGTTVTVSS	212	235	287	310	425	487	DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPNLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPWTFGQGTKVEIK	172	189	241	249	358	384
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARLPSPYDSSGYPDAFDIWGQGTMVTVSS	204	233	285	305	420	473	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPLTFGGGTKVEIK	186	203	255	263	372	398
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDDYWGQGTLVTVSS	213	236	288	311	426	440	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPVTFGPGTKVDIK	186	203	255	263	372	401
QVQLVQSGSELKKPGASVKVSCKASGYTFTSYAMNWVRQAPGQGLEWMGWINTNTGNPTYAQGFTGRFVFSLDTSVSTAYLQISSLKAEDTAVYYCARADMIDYGVSLNWFDPWGQGTLVTVSS	182	205	257	280	395	445	SYVLTQPPSVSVAPGKTARITCGGNNIGSKSVHWYQQKPGQAPVLVIYYDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVVFGGGTKLTVL	173	190	242	250	359	394
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARFMPQNFYYYYGMDVWGQGTTVTVSS	168	191	243	263	378	425	QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGVWVFGGGTKLTVL	167	193	245	253	362	388
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCASPGGFGELLYPRGYYGMDVWGQGTTVTVSS	191	214	266	289	404	463	DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPYTFGQGTKLEIK	175	192	244	252	361	387
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASWYYDILTGYYNWGQGTLVTVSS	175	204	256	276	391	429	QSALTQPASVSGSPGQSITISCTGTSSDVGSYNLVSWYQQHPGKAPKLMIYEGSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSSVVFGGGTKLTVL	171	197	249	257	366	392
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSYYDMHYYYYGMDVWGQGTTVTVSS	213	236	288	311	426	473	DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPYTFGQGTKLEIK	172	189	241	249	358	384
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKRLGLCSSTSCYSFQGDAFDIWGQGTMVTVSS	218	241	293	316	431	496	QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL	180	203	255	263	372	404
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHAPMVRGVMGAFDIWGQGTMVTVSS	158	187	239	259	374	418	QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPVFGGGTKLTVL	198	221	273	281	390	422
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTREGGATGDAFDIWGQGTMVTVSS	213	236	288	317	432	470	QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGYDVHWYQQLPGTAPKLLIYGNSNRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDSSLSGHVVFGGGTKLTVL	184	210	262	270	379	414
EVHLVESGGGLVQPGGSLRLSCAASGFIFSSYGMHWVRQAPGKGLVWVSRINSDGSITNYADSVKGRFTISRDNAKNTLSLQMNSLRAEDTAVYFCTRSNKGHCSGVGCYLGPEYWGQGTLVTVSS	242	265	317	340	455	511	QSVLTQPPSASGTPGRRVTISCSGSSSNVGSNTVNWYQHLPGMAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL	180	203	255	263	372	404
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDGSKNTLYLQMNSLKTEDTAIYYCTTDTSWGPYYFDYWGQGTLVTVSS	213	236	288	317	432	470	QSALTQPASVSGSPGQSITFSCTGTSSDVGSYNPVSWYQQHPGKAPKLMIYEDSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGTSTWVFGGGTKLTVL	171	197	249	257	366	395
QLQLQESGSGLVKPSQTLSLTCAVSGGSISSGGYSWSWIRQPPGKGLEWIGYIYHSGSTYYNPSLKSRVTISVDRSKNQFSLKLSSVTAADTAVYYCARVVSLVKAFDIWGQGTMVTVSS	168	197	249	269	384	419	QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTDVFGTGTKVTVL	174	200	252	260	369	398
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGTYCSGGSCYSPKRTVEKDYYYYGMDVWGQGTTVTVSS	212	235	287	310	425	511	DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPWTFGQGTKVEIK	175	207	259	267	376	402
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKNIPLPGIAVAGSFDYWGQGTLVTVSS	212	235	287	310	425	475	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPLTFGGGTKVEIK	186	203	255	263	372	401
EVQLVESGGGLVQPGGSLRLSCVASGFSTSNYWMGWVRQAPGKGLEWVANIKQDGSEKYYGDSVKGRFTISRDNAKNSLYLQINSLRAEDTAVYYCARAHSGGIGARLYWGQGTLVTVSS	212	235	287	310	425	463	EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCHQYDNWPWTSGQGTKVEIK	175	192	244	252	361	387
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAATLVPAATQSPDYWGQGTLVTVSS	212	235	287	310	425	466	AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPPTFGQGTKLEIK	172	189	241	249	358	384
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARVGSSGWYNGDYYYYGMDVWGQGTTVTVSS	200	223	275	298	413	472	DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK	180	197	249	257	366	392
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRFLHAGIAAAVDYWGQGTLVTVSS	206	229	281	304	419	466	DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNSLTFGGGTKVEIK	176	193	245	253	362	385
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARGLLAAAGNYYYYGMDVWGQGTTVTVSS	195	218	270	293	408	461	SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDLGGVFGGGTKLTVL	258	275	327	335	444	479
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCARARNHLKYSSSSSHYYYYGMDVWGQGTTVTVSS	197	220	272	295	410	478	QTVVTQEPSFSVSPGGTVTLTCGLSSGSVSTSYYPSWYQQTPGQAPRTLIYSTNTRSSGVPDRFSGSILGNKAALTITGAQADDESDYYCVLYMGSGIWVFGGGTKLTVL	178	204	256	264	373	402
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRGPYGDSTYYYYGMDVWGQGTTVTVSS	213	236	288	317	432	482	QPVLTQPPSASASLGASVTLTCTLSSGYSNYKVDWYQQRPGKGPRFVMRVGTGGIVGSKGDGIPDRFSVLGSGLNRYLTIKNIQEEDESDYHCGADHGSGSNFVFVFGGGTKLTVL	170	190	242	265	374	412
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAPRARSSRVDYFDYWGQGTLVTVSS	179	208	260	280	395	442	VIWMTQSPSLLSASTGDRVTISCRMSQGISSYLAWYQQKPGKAPELLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSFPYTFGQGTKLEIK	172	189	241	249	358	384
QVQLVQSGAEVKKPGASVKVSCKASNYPFTTYGISWVRQAPGQGLEWMGWINAYNGNTNFAQKLQDRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARDGSGTWNDYWGQGTLVAVSS	192	215	267	290	405	437	QLVLTQSPSASASLGASVKLTCILSSGHSSYAIAWHQQQPEKGPRYLMKVNRDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIQVFGGGTKLTVL	158	178	230	250	359	385
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAGPAYCSGGSCYSEPYHYYYYGMDVWGQGTTVTVSS	170	193	245	265	380	460	SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTAVVFGGGTKLTVL	219	236	288	296	405	434
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTVTRGYRSNWFDPWGQGTLVTVSS	213	236	288	317	432	473	SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHPVFGGGTKLTVL	267	284	336	344	453	485
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARLLYDEWEGYWGQGTLVTVSS	212	235	287	310	425	457	QLVLTQSPSASASLGASVKLTCTLSSGHSSYAIAWHQQQPEKGPRYLMKLNSDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIVFGGGTKLTVL	158	178	230	250	359	382
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGGYYWSWIRQHPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGDYGDPPGYYGMDVWGQGTTVTVSS	192	221	273	293	408	455	AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPWTFGQGTKVEIK	172	189	241	249	358	384
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKVWGRLLWFGSPFDYWGQGTLVTVSS	212	235	287	310	425	472	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK	183	203	255	263	372	398
EVQLMESGGGVVQPGGSLRLSCAASGFTFSWFWMSWVRQAPGKGLEWVASIKPDGSEKYYVESVKGRLIISRDNANNEMYLQMNSLRAEDTAVYYCATEDKSAFESWGQGTLVTVSS	212	235	287	310	425	454	QSVLMQPPSVSAAPGQTVTISCSGSSSSIGNNFVSWYQLLPGAAPKLLIYENNKRPSGVPDRFSASKSGTSATLGITGLQTGDEADYYCGSWDRKVLGTGTKVTVL	169	192	244	252	361	381
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDTLIAAAGARHLLYGMDYWGQGTLVTVSS	213	236	288	317	432	491	DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK	176	193	245	253	362	388
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDAAGTLWDTAMEGLGYYYYYYMDVWGKGTTVTVSS	212	235	287	310	425	502	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSRGTFGQGTKVEIK	191	211	263	271	380	406
EVQLVDSGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLFLQMNSLKTEDTAVYYCTTGDNWNYFYWGRGTLVTVSS	213	236	288	317	432	461	SYELTQPPSVSVSPGQTASITCSGDNLGNKYASWYQQKPGQSPVLVIYQDNKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTARFGGGTKLTVL	170	187	239	247	356	382
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARALYGDSVNYYYYGMDVWGQGTTVTVSS	212	235	287	310	425	478	QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAGVFGGGTKLTVL	169	192	244	252	361	393
QVQLQESGPGLVKPSETLSLTCTVSGGSITSDYWTWIRQPPGKGLEWIGYIYYSGNINYNPSLRSRVTISVDMSKNQFSLKLSSVTAADTAVYYCARYQYGAGPFDIWGQGTMVTVSS	170	193	245	265	380	415	DIQMTQSPPTLSASVGDRATITCRASQSISNRLAWYQQKPGKAPKLLIYKASTLESGVPSRFSGSGSGTEFTLTITSLQPDDFATYYCQQYDNYFRTFGQGTKVEIK	172	189	241	249	358	384
EVQLVESGGGLVQPGESLRLSCAASGFTFSDYSMAWVRQAPGKGLEWVANINQDGTKKNHLGSVTGRFAISRDNAKNSLYLQMNSLRAEDTAVYYCARDLGGRYDFWSHWGQGTLVAVSS	212	235	287	310	425	463	DIQMTQSPSSVSASIGDRVTITCRASHDIDGWLAWYQQKPGKAPKLLVYAASRLQSGVPSRFSGSGSGTDFALTISRLQPEDFATYYCHQANSFPLTFGGGTKVEIK	172	189	241	249	358	384
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDVGDKHYTDSVKGRFTISRDNSKNTLYLQMNSLRAEDTGVYYCARDTSAPFDSWGQGTLVTVSS	200	223	275	298	413	442	DIQMTQSPSSLSASVGDRVTITCRASQGINSYLAWFQQKPGKAPKSLIYAASTLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIK	172	189	241	249	358	384
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARVCSSTSCYPKKDGWFDPWGQGTLVTVSS	170	193	245	265	380	436	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPSTFGQGTKLEIK	183	203	255	263	372	398
QLQLQESGPGLVKSSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSSYHNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYFCASLTTVTTFGYWGQGTLVTVSS	174	203	255	275	390	422	QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSVSAWVFGGGTKLTVL	169	192	244	252	361	393
EVQLVESGGGLVQPGRSLRLSCAASGFTFGNYAMYWVRQIPGKGLEWVSGISWNSDTIGYADSVKGRFTISRDNAKNSLYLQMNSLRVEDTAMYYCAKVGGLGSYYYTPIESWGQGTLVTVSS	228	251	303	326	441	488	DIQLTQSPSFLSASVGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCQQLNSYPRTFGQGTKVEIK	172	189	241	249	358	384
EVQLMESGGHLVQPGGSLKLSCAASGFTFSDYSMDWVRQAPGKGLEWVARMRDKAYTYTTQYAASVKGRFTISRDDSKSLVYLQMNSLKTEDTAVYYCSRDSYGNPDYWGQGTLVTVSS	213	236	288	317	432	461	DIQMTQSPSSLSASVGDRVTITCRASQDIRNDLGWYQQKPGKAPKRLIYATSTLQSGVPSRFSGSGSGTEFTLTITSLQPEDFATYYCLQYNTYPGTFGQGTKVEIK	181	198	250	258	367	393
QVQLQQSGPGLVKPSQTLSVTCAISGDSVSSNTATWNWIRQSPSRGLEWLGRTYFRSKWFYDYALSVKSRITINADTSRSQFSLQLNSVTPEDTAVYYCARERRFTFFGVVTRTNWYFDLWGRGTLVTVSS	188	217	269	295	410	472	SSELTQDPAVSVALGQTVRITCQGDSLRNYYASWYQQKPGQAPLLVIYGENYRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNVVVFGGGTKLTVL	173	190	242	250	359	391
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKDESSGWYVFDYWGQGTLVTVSS	217	240	292	315	430	468	QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYTWVFGGGTKLTVL	175	201	253	261	370	399
EVQLVESGGGLIKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRFMSKTDGGTTDYAAPVKGRFTVSRDDSKNTLYLQMNSLKTEDTAVYYCTAGTGRTDHDYWGQGTLVTVSS	213	236	288	317	432	464	DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNFLAWYQQKAGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYMTPLTFGGGTKVEIK	169	204	256	264	373	399
QVQLQESGPGLVKPSETLSLTCTVSGYSISSGYYWGWIRQPPGKGLEWIGSIYHSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDLNSGLIDYWGQGTLVTVSS	173	199	251	271	386	418	QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQLPGTAPKLLIYRNNQRPSGVPDRFSGSKSGTSASLAISGLRSEDEADYYCAAWDDSLSVLFGGGTKLTVL	180	203	255	263	372	401
EVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARLRRDGYNSWDWFDPWGQGTLVTVSS	242	265	317	337	452	499	DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQHRHTFGQGTKLEIK	172	189	241	249	358	372
EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARANRGAGFSTVPMRDKGFFAFDIWGQGTMVTVSS	212	235	287	307	422	493	EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPGITFGQGTRLEIK	175	192	244	252	361	393
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYDINWVRQATGQGLEWMGWMNPNSGNTGYAQKFQGRVTMTRNTSISTAYMELSSLRSEDTAVYYCARFTPKEPDYFDYWGQGTLVTVSS	191	214	266	289	404	442	DIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKRLIYAASSLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCLQHNSYPWTFGQGTKVEIK	165	182	234	242	351	377
QVQLVQSGSELKEPGASVKVSCRASGYSFTSYAVNWVRLAPGQGLEWMGWINTDTKNPTYARDFTGRFVFSLDTSVDTAYLQISSLRAEDTAVYYCARHSAALGLPDYWGQGTLVTVSS	182	205	257	280	395	430	DIQMTQSPSSLSASVGDRVTITCRASQPFSNYLAWYQQKPGKVPQLLIYSASTLQSGVPSRFSGSGSWTTFTLTINNLQPEDAATYYCQKHNSAPLTFGQGTKVEIE	172	189	241	249	358	384
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDRVVVVAATGYYYYGMDVWGQGTTVTVSS	213	236	288	317	432	491	SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTVFGGGTKLTVL	170	187	239	247	356	379
EVQLVQSGAEAKKPGESLRISCKTSGYSFSSYWIGWVRQMPGKGLEWMGNFYPGDSDTRYSPSFQGQVTISADWSITTAYLQWSSLKASDTAIYYCARGLYYSFLTGHYNGNVAFDIWGQGTMVTVSS	192	215	267	290	405	467	DIVMTQSPDSLAVSLGERATINCRSSQSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPERFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSNPYTFGQGTKVEIK	169	204	256	264	373	399
DVQLVESGGGLVKPGGSLRLSCVASGFTFSRQSMHWVRQAPGKGLEWVSSITSRSDFIYYRDSVKGRFTISRDNARNSLFLQMTSLRAEDTAVYYCARDETTLGGDWGRGTLVTVSS	212	235	287	310	425	454	QSVLTQPPSASGTPGQRVTISCSGSSSNIGSRTVNWYQQLPGTAPRLFIYNNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDVSLSGWVFGGGTKLTVL	180	203	255	263	372	404
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARGATMVRGRIDPWGQGTLVTVSS	191	214	266	289	404	442	QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNNLVFGGGTKLTVL	174	200	252	260	369	398
QVQLQESGPGLVKPSETLSLTCSVSGYSITSGHYWGWIRQSPEKGLEWIGSIYKSGTTYYNPTLNSRVTMSVDTSKNQFSLNLSSVSASDTAVYYCARGRQWLMYYFDYWGQGALVTVSS	174	200	252	272	387	425	EIVLTQSPGTLSLSPGESATLSCRASQSVSTTYLAWYQQRPGQAPRLLIYGGSGRATDIPDRFTGSGSGTDFTLTISRLEPEDFGVYYCQQYGSSVTFGGGTKVEIK	191	211	263	271	380	403
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCARDQGFELWLLYYWGQGTLVTVSS	191	214	266	289	404	442	DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPRTFGQGTKLEIK	169	204	256	264	373	399
EVQLLESGGGLVQPGGSLRLSCAASGFTFRNYAMSWVRQAPGKGLEWVSAVRGSGNDPYYADSVKGRFTISRDNSRNTLYLQMNSLRAEDTAVYYCAKILTTVTTFEYFQDWGQGTLVTASS	212	235	287	310	425	469	DIQMTQSPSSVSASVGDRVTITCRATEDINNWLAWYQQEPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISGLQPEDFATYYCQQAKSFPLTFGGGTKVEIK	172	189	241	249	358	384
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARGAYMVRGVSHHYYYYMDVWGKGTTVTVSS	212	235	287	310	425	484	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK	183	203	255	263	372	398
EVQLVESGGGLVPPGGSLTLSCAASGFTLSNYWLYWVRQSPGKGLEWVAYFKGDGSSTKFADSVKGRFTFSRGNARNILYLQMNNLRAEDTAMYYCARDGPAIMVDFDFWGRGTLVTVSS	203	226	278	301	416	454	DIVMTQAPLSLPVTPGEPASISCRSSQSLLHSSGYNFLDWYLQKPGQSPQLLIYLGSSRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQAPITFGQGTRLEIK	174	206	258	266	375	401
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGRINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCAVGRIYDSSGYYALAGYFDYWGQGTLVTVSS	197	220	272	295	410	469	EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPLTFGGGTKVEIK	183	203	255	263	372	398
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHSAGEILDFDYWGQGTLVTVSS	157	186	238	258	373	408	QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNLRVFGGGTKLTVL	174	200	252	260	369	398
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARAPRFGFWSGYSYGMDVWGQGTTVTVSS	197	220	272	295	410	463	QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTYVFGTGTKVTVL	174	200	252	260	369	398
QVQLQESGPGLVKPSQTLSLTCSVSGGSIRSGGYHWNWIRQCPGKGLEWIGYIDDRGNTEYDASLRSRGVISVDRSLKQFSLRLTSVTAADTAVYYCARDKDETGIGSFDQWGRGTLVTVSS	193	222	274	294	409	450	DIVMTQSPDSLAVSLGERATISCKSSQSILNRSNNKNYLAWYQQKPGQPPKLLVYWASTRESGVPDRFSGSGSGTDFTLSISSLQAEDVAVYYCQHYFSRPFTFGQGTKLEIK	169	204	256	264	373	399

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Paired SARS-COV-2 heavy/light chain sequences from the Observed Antibody Space database

Human paired heavy/light chain amino acid sequences from the Observed Antibody Space (OAS) database obtained from SARS-COV-2 studies.

https://opig.stats.ox.ac.uk/webapps/oas/

Please include the following citation in your work:

 Olsen, TH, Boyles, F, Deane, CM. Observed Antibody Space: A diverse database of cleaned, annotated, and translated unpaired and paired antibody sequences. Protein Science. 2022; 31: 141–146. https://doi.org/10.1002/pro.4205

Data Preparation

This data was obtained on August 3, 2023 by searching the OAS Paired Sequence database with the following criteria:

Species = "human"
Disease = "SARS-COV-2"

This returned 704,652 filtered sequences from 3 studies split across 63 .csv.gz data unit files. These were extracted and filtered for records where both the complete_vdj_heavy and complete_vdj_light values were "T". Finally, the sequence_alignment_aa_heavy and sequence_alignment_aa_light fields were extracted into dataset and a 90/10 train/test applied. The resulting data was saved in pyarrow format.

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Size of downloaded dataset files:

55.8 MB

Size of the auto-converted Parquet files:

55.8 MB

Number of rows:

641,744