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Hodgkin lymphoma first lymphomas recognized specific disease entity . Recent studies highlighted heterogeneity diseases associated eponym warranting clarification . |
Chimeric antigen receptor (CAR) T-cell therapies demonstrated efficacy relapsed/refractory large B-cell lymphoma (LBCL) associated cytokine release syndrome (CRS) neurological events (NE) We wanted |
A 56-year-old woman diagnosis diffuse large B-cell lymphoma dyspnea, weakness left upper extremity vocal cord paralysis . She underwent cervical, thoracal lumbosacral magnetic resonance imaging (MRI) However |
Primary cardiac lymphoma (PCL) extremely rare fatal fatal heart neoplasm . Primary cardiac non-Hodgkin lymphoma (NHL) uncommon, considering rarity pericardial diffuse large B-cell lymphoma ( |
C-MYC expression immunohistochemical stain (IHC) shown independent prognostic factor DLBCL . In clinical setting, MYC stain currently evaluated manual quantification minimum positivity cut-off 40% . |
Human immunodeficiency virus (HIV) infected patient caused patient suffer Garcin syndrome . In study, report parapharyngeal diffuse large B-cell lymphoma human immunodeficiency virus (HIV) infected patient caused |
Chronic lymphocytic leukemia (CLL) experience histological transformation aggressive lymphoma called "Richter's transformation" This transformation usually leads diffuse large B cell lymphoma, though cases T cell lymphoma identified . |
115 DLBCL patients admitted hospital treatment June 2020 June 2021 . 115 DLBCL patients admitted hospital treatment June 2020 June 2021 . 65 healthy subjects received physical examination hospital period selected healthy control group . |
Primary mediastinal B-cell lymphoma (PMBCL) rare type diffuse large B-cell lymphoma . PMBCL typically presents large, fast-growing tumor limited mediastinum . R-CHOP commonly used |
Tumour cells develop accumulating changes genome result changes main cellular processes . Aberrations basic processes replication chromatin reassembly particularly important genomic (in)stability . |
The main function cartilage oligomeric matrix protein (COMP) maintain synthesis stability extracellular matrix interacting collagen . At present, relatively studies role protein tumors . This study aimed explore relationship COMP pan-cancer, analyzed diagnostic prognostic |
Follicular lymphoma (FL) generally indolent B cell lymphoproliferative disorder transformed follicular center B cells . FL characterized diffuse lymphadenopathy, bone marrow involvement, splenomegaly. Cytopen |
We report case middle-aged man unusual case bullous lichen sclerosus complicated morphea . He showed initial recurrent flaccid bullae, followed ivory-white sclerotic plaques extensive skin sclerosis, additional walking disorder |
Meta-analysis research explored findings previous studies highlighted efficacy of HD and/or IT CNS prophylaxis in DLBCL patients intermediate high risk . Aim is to answer following research questions: (1) Is difference CNS relaps rel |
Isatuximab (Isa, anti-CD38 antibody) combination cemiplimab (Cemi) combination cemiplimab (Cemi) isatuximab (Isa, anti-CD38 antibody |
Circulating tumor DNA (ctDNA) become investigated analyte blood . It shed tumor circulation represents subset total cell-free DNA (cfDNA) pool released peripheral blood . |
Direct comparisons effectiveness of novel therapies diffuse large B-cell lymphoma (DLBCL) treatment landscape range head-to-head randomized phase 3 trials would time-consuming costly . Comparative effectiveness studies using real-world data (R |
Patients with diffuse large B-cell lymphoma (DLBCL) undergo HCT 2008 2020 . DLBCL underwent HCT 2008 2020 . DLBCL underwent HCT 2008 2020 . DLBCL underwent HCT 2008 2020 . |
Febrile neutropenia risk prediction models important clinical practice, external validation limited . |
61-year-old man presented three distinct tumors concurrently 2021: noninvasive urothelial carcinoma bladder, diffuse large B-cell lymphoma, squamous cell carcinoma lung . MPMs defined coexistence at least two |
Epstein-Barr virus (EBV) considered carcinogenic virus, associated high risk poor prognosis lymphoma patients . We aimed identify immunological microenvironment molecular signatures lead poor prognosis EBV+ lymphoma patients . Differential genes |
The incidence cardiac lymphoma is low, mainly occurs secondary non-Hodgkin's lymphoma, particularly diffuse large B-cell lymphoma . |
Macrophage-capping protein (CAPG) discovered play crucial part regulator various cancers . It still remains unclear regarding regulatory mechanism of DLBCL . |
Diffuse large B-cell lymphoma (DLBCL) common aggressive non-Hodgkin lymphoma, 10% DLBCL cases primarily occur gastrointestinal tract . Primary gastrointestinal-DLBCL (pGI-DLBC |
RNA expression profiling using next-generation sequencing provides reliable reproducible information biology cancer . RNA expression profiling using next-generation sequencing provides reliable reproducible information biology cancer . |
Primary adrenal lymphoma (PAL) extremely rare entity, cases reported . Symptoms atypical, making difficult obtain accurate early diagnosis . |
We investigated clinicopathologic features 5 follicular lymphomas (FL) transformed morphologic diffuse large B-cell lymphomas (DLBCL) primary mediastinal large B-cell lymphoma (PMBL) lymphoma (PM |
WHO classification haematolymphoid tumours worldwide accepted reference malignant tumours myeloid lymphoid system . The REAL classification 1994 laid foundations WHO volumes, continous development specification date [3, 5, 6]. In 5 |
Metal ions play role pathogenesis lymphoma . Metal ions play role pathogenesis lymphoma . |
High-dose methotrexate (HD-MTX) standard therapy primary central nervous system lymphoma (PCNSL) prognosis remains poor . Because 90% PCNSL diffuse large B-cell lymphoma (DLBC |
We present case older male adult adult adult adult primary spinal diffuse large B-cell lymphoma (DLBCL) presenting spinal cord compression treated surgery followed high dose methotrexate combination RCHOP . |
Recent reports suggest aggressive non-Hodgkin lymphomas might benefit concomitantly receiving statins rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine (On |
PSENHLs diffuse large B-cell lymphomas commonly caused chronic inflammatory process, chronic infection, autoimmune disease . The majority PSENHLs diffuse large B-cell lymphomas are commonly caused chronic inflammatory process, chronic infection, autoimmune |
Diffuse large B cell lymphoma (DLBCL) aggressive subtype non-Hodgkin lymphoma accounts third NHL cases . A significant proportion of treated DLBCL patients develop refractory relapsed disease due drug resistance |
Intravascular large B-cell lymphoma (IVLBCL) uncommon lymphoma aggressive clinical course characterized selective growth tumor cells within vessels . Pathogenesis still uncertain little information underlying genomic alterations . |
Diffuse large B cell lymphoma (DLBCL) involve almost organ, prognosis patients DLBCL different primary sites varies greatly . 5-Hydroxymethylcytosine (5hmC) plays vital role tumor |
CAR-T cell therapy approved patients with leukemia diffuse large B-cell lymphoma . Its use subsequent toxicities expected rise coming years . Cytokine release syndrome observed 40% patients . |
Single-centre study aimed determine clinicopathological characteristics prognosis patients co-existing FL DLBCL components (FL/DLBCL) Among 56 FL/DLBCL cases analysed, 67.9% germinal centre |
The subclassification of diffuse large B-cell lymphoma (DLBCL) germinal center B-cell-like (GCB) activated B-cell-like (GCB) activated B-cell-like (ABC |
Diffuse large B-cell lymphoma (DLBCL) common type B-cell lymphoma . Multilobated subtype DLBCL observed since 1970s, little known clinical significance unique variant era rituximab |
Antiretroviral therapy may alter susceptibility nonkeratinocyte skin cancers (NKSCs) improving immunity people living HIV (PLWH) Using linked data HIV cancer registries 12 US states/regions ART era (1996- |
circulating tumor DNA (ctDNA) has been developed to detect lymphoma sensitively tumor-derived DNA . This article discusses various methods ctDNA detection clinical context applied variety lymphoma subtypes . |
Diffuse large B cell lymphoma (DLBCL) common pathological subtype non-Hodgkin lymphoma (NHL) common type adult lymphoma . New drug targets therapeutic methods urgently needed . |
64-year-old man underwent liver transplantation, presented chest pain exertional dyspnea, developed huge cardiac mass within 2 months passed away day 3 hospitalization . Histological examination revealed diffuse large B-cell lymphoma (DL |
19-year-old man diagnosed with large B-cell lymphoma undergoing chemotherapy presented recurrent emesis weight loss . Endoscopic ultrasound-guided gastroenterostomy using lumen-apposing metal stent performed bypass obstruction . Subsequently |
Patients cartilage-hair hypoplasia (CHH) increased risk of non-Hodgkin lymphoma basal cell carcinoma . Lymphoma diagnosis remains unexplored, but clinical course, response therapy outcome lymphomas CHH |
Primary human herpesvirus 8 (HHV8)-unrelated effusion large B-cell lymphoma (ELBCL) recognized new clinical entity . Pathogenesis therapeutic strategies remain largely unknown . |
PD-L1 human lymphomas were analyzed using hyperspectral imaging (HSI) and fluorescent multiplex immunohistochemistry (mIHC) We analyzed expression PD-L1 human lymphomas using hyperspectral imaging ( |
Patients angioimmunoblastic T-cell lymphoma (AITL) treated cyclophosphamide, doxorubicin, vincristine prednisone without etoposide (CHO(E) |
Gene expression involved B lymphocyte differentiation maturation within germinal center (GC) regulated epigenetically lymphomas . Episodes play critical roles pathogenesis of GC-driven lymphomas . |
Given mixed evidence carcinogenicity current-use herbicides, studied relationship occupational herbicide use risk non-Hodgkin's lymphoma (NHL) NHL is a large, pooled study of 10 case-control studies . |
Adaptor protein transducin β-like 1 (TBL1X) homolog TBL1XR1 shown upregulated solid tumors hematologic malignancies, overexpression associated poor clinical outcomes . Dysregulation T |
Diffuse large B-cell lymphoma (DLBCL) common non-Hodgkin lymphoma around world . R-CHOP significantly improved patient outcomes, subset patients still poor outcome . |
Splenocolic fistula extremely rare condition described literature . A fistula connects bowel organs, urinary bladder small intestine, small intestine . It occurs cases splenic tumors, including splenic diffuse large B cell lymphoma . |
Despite mounting evidence causal role increasing number lymphoma subtypes, studies systematically tested entire spectrum Hodgkin non-Hodgkin lymphomas presence Epstein-Barr virus (EBV) Here, describe prevalence EBV large, unselected |
Coronavirus disease 2019 (COVID-19) spread worldwide . Vaccination recommended one effective countermeasures control pandemic prevent worsening symptoms . However, adverse effects attracting attention . |
This subtype CNS lymphoma diffuse large B-cell Epstein-Barr virus-positive . Its accurate presurgical diagnosis often unfeasible appears ring-enhancing lesions mimicking glioblastoma metastasis . |
Dogs diffuse large B-cell lymphoma (DLBCL) diagnosed with diffuse large B-cell lymphoma (DLBCL) diagnosed with inferior survival times . Specific biomarkers inflammation identified prognostic indicators dogs DLBCL . |
Burkitt lymphoma accounts majority pediatric non-Hodgkin lymphomas less common significantly lethal diagnosed adults . We sought to identify somatic changes underlie lymphomagenesis aBL molecular features associate clinical disparities within pBL aBL |
POLARIX study shown improvement standard backbone rituximab plus cyclophosphamide, doxorubicin, vincristine, prednisone frontline setting . In relapsed refractory setting, two unique |
PLD epirubicin (PLD) dose intensity survival outcomes . The study showed PLD epirubicin similar efficacy (overall survival (OS) p = 0.776; progressio . |
Double-expressor lymphoma (DEL) associated poor prognosis . R-CHOP DA-EPOCH-R first-line therapy patients DEL urgently needed . |
Ocular adnexal lymphoma relatively rare disease one common malignancies ocular adnexa, incidence steadily increasing . Ocular adnexal lymphoma consists mainly four histopathological subtypes non-Hodgkin B |
We report establishment novel activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) cell line . TMD12 cells isolated pleural effusion patient relapse passaged continuously vitro >4 years . |
Clonality assays antigen receptor rearrangement used adjunct examinations lymphoproliferative diseases . Canine diffuse large B cell lymphomas (DLBCL), cutaneous pla, cutaneous pla, and diffuse large B |
Primary adrenal lymphoma (PAL) aggressive form lymphoma associated adrenal insufficiency (AI) cases . It requires histologic confirmation unlike cases primary AI . |
Primary orbital lymphoma accounts essential part adult orbital malignancies . It accounts for <1% non-Hodgkin's lymphoma cases . Orbital diffuse large B-cell lymphoma (DLBCL) one prevalent subtype |
Diffuse large B-cell lymphoma (DLBCL) common subtype adult lymphomas . Patients often difficulty tolerating standard chemotherapy regimens due comorbidities . |
Chinese patients follicular lymphoma (FL) limited. Here, conducted retrospective study explore initial treatment strategies . Chinese patients newly diagnosed Tianjin Medical University Cancer Institute Hospital March 2002 August 2020. A total 926 FL patients enrolled. The median |
Inhibitors targeting Bruton's tyrosine kinase (BTK) revolutionized treatment various B-cell malignancies . |
PD-1/PD-L1 pathway pathway played role in PD-1/PD-L1 pathway . Thirty-four cases (64.2%) showed high expression PD-L1 . |
Previous studies shown diffuse large B-cell lymphoma (DLBCL) subtype B-cell antigen receptor complex-associated protein beta chain (CD79B) myeloid differentiation primary response 88 mutations (MYD88) inferior |
56-year-old patient underwent tracheal sleeve pneumonectomy . Complex pulmonary aspergilloma invading almost entire right lung carina . |
Elderly Prognostic Index (EPI) based integration simplified geriatric assessment, hemoglobin levels and hemoglobin levels . EPI validated predict overall survival of older patients with diffuse large B-cell lymphoma (DLBCL) |
A 57-year-old male came hospital complaining abdominal pain complaining of abdominal pain . He underwent abdominal computed tomography contrast, showed full-thickness wall thickening ileocecal region . He underwent lower gastrointestinal endosc |
The role of Helicobater pylori eradication treatment high-grade diffuse large B-cell lymphoma (DLBCL) is unclear . We performed systematic review meta-analysis of currently available data . |
Cardiac lymphoma (CL) rare life-threatening clinical condition . Most cases diagnosed late period . Most cases diagnosed late period . |
Diffuse large B-cell lymphoma (DLBCL) common type lymphoma worldwide, accounting 40% cases . IL-20 expressed frequently follicular lymphoma (94%) Burkitt lymphoma (81%) and mantle c lymph |
Methotrexate-associated lymphoproliferative disorder (MTX-LPD) occur oral cavity, cases palatal involvement reported . Chemotherapy may needed remission withdrawal MTX . |
Patients renal impairment (RI) typically excluded trials evaluating chimeric antigen receptor (CAR) T cell therapies . We evaluated outcomes patients receiving standard care (SOC) CAR T cell therapy relapsed/refractory (R/R) |
We retrospectively reviewed renal pathology profiles January 2010 December 2021, 28 patients B-cell LPD combined intact renal biopsy data included . There 20 men eight women aging 41 79 years time renal biopsy (median age 62 years) |
Core needle biopsies (CNB) may not meet increasing tissue requirements clinical trials . Core needle biopsies may not meet increasing tissue requirements . This potentially lead selective enrollment patients undergo excisional biopsy . |
Relationship between Epstein-Barr virus-encoded small RNA (EBER) early treatment lymphoma remains unclear . We explored discrepancies PEDL variables associated with PEDL variables associated with PEDL variables . Median PEDL |
Autologous stem cell transplantation (ASCT) chimeric antigen receptor (CAR) T-cells two therapeutic options relapsed/refractory diffuse large B-cell lymphoma . Both intensive potentially curative therapies differ efficacy toxicity |
B-cell lymphoma 6 (BCL6) protooncogene adult pediatric cancers . First identified diffuse large B-cell lymphoma (DLBCL) acts repressor tumor suppressor TP53 . BCL6 expression normal |
Lymphomas affecting sublingual glands extremely rare case reports currently available . Lymphomas affecting sublingual glands extremely rare case reports currently available . Aim current study describe clinicopathological features series lymphomas involving sublingual glands . |
EFS24 established endpoint diffuse large B-cell lymphoma (DLBCL) follicular lymphoma (FL) role undefined MCL . To evaluate prognostic role EFS24 MCL. |
Until recently, molecular bases disease subtypes unclear . Specific genetic characteristics distinguish subtypes respective systemic counterparts . |
107 patients OL treated 14-year period Polish hematological centers . Median patient age 60 years (range 51-71) Median patient age 60 years (range 51-71) Median patient age 60 years (range 51-71) |
Long non-coding RNAs (lncRNAs) confirmed connected tumor proliferation, apoptosis, metastasis recurrence . Previous studies indicated lncRNA calcium voltage-gated channel subunit α1 G (CACNA |
Duodenal-type follicular lymphoma (D-FL) recognized rare entity accounts approximately 4% primary gastrointestinal lymphomas . D-FL follows indolent clinical course compared common nodal FL generally considered better prognosis . |
Diffuse large B-cell lymphoma (DLBCL) heterogeneous disease existing prognosis systems based clinical variables difficult stratify patients accurately . Nutritional indices play meaningful role prognosis solid tumors, whereas effect DLBCL still equ |
Central nervous system (CNS) lesions peripheral neuropathy rare among patients non-Hodgkin's lymphoma (NHL) Central nervous system (CNS) lesions peripheral neuropathy rare among patients non-Hodgkin |
Diffusion large B cell lymphoma (DLBCL) developed range new treatment programs based characteristics disease, bringing us era immune-chemotherapy . However, effectiveness molecular mechanisms of targeted-immunotherapy remain unclear . Targeted- |
59-year-old male enlargement treated with Burkitt-like lymphoma (BLL) Cytogenetics revealed absence of absence MYC rearrangement involving MYC rearrangement involving MYC rearrangement |
Nail changes well-known phenomenon T-cell lymphoma reported widely B-cell lymphomas Hodgkin lymphomas . |
Next-generation sequencing (NGS) elucidates diffuse large B-cell lymphoma (DLBCL) genetic characteristics . Study included 20 patients DLBCL. |
Diffuse large B-cell lymphoma (DLBCL) common aggressive non-Hodgkin's lymphoma (NHL) accounting 30%-40% adult NHL . Primary testicular (PT) lymphoma uncommon extran |
Diffuse large B-cell lymphoma (DLBCL) heterogeneous non-Hodgkin's lymphoma great clinical challenge . Machine learning (ML) attracted substantial attention diagnosis, prognosis, treatment diseases . |
Primary pancreatic lymphoma rare; commonly described subtype diffuse large B-cell lymphoma . Although morphologically similar lymphoproliferative lesions found locations, clinically mimic epithelial neoplasm . The differential diagnosis important due due different |
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