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32357477_ijms-21-03049-f006
[ { "from": "human", "value": "Illustrate the image through a descriptive explanation\n<image>" }, { "from": "gpt", "value": "Determination of metaphase II entry in oocytes pre-exposed to ferrocenyl 4-(alkylamino)-1,4-dihydroquinolines. After incubation or not with compounds 9, 6, 10, 7, 11, 8 for 24 h, oocytes were rinsed four times in ND96 for 30 min, before progesterone stimulation. White spot appearance was scored after 15 h. N refers to the number of females and n to the number of oocytes (N = 2 and n = 60)." } ]
17096591_pcbi-0020151-g003
[ { "from": "human", "value": "Illustrate the image through a descriptive explanation\n<image>" }, { "from": "gpt", "value": "Polar Localization of Lipid Clusters Elastic energy parameters are fixed (κ = 25 k = 0.25 k/nm4, γ = 0.4 nm−1), with varying short-range attraction (A) ɛ = 1 k (B) ɛ = 1.5 k and (C) ɛ = 2.5 k. The rectangles on the left and right represent the cell poles and have slightly enhanced cell-wall curvature, γ pole = 0.04 nm−1. The three-dimensional figure in (D) represents the lipid position and the membrane height in (C) mapped onto the surface of a capped cylinder. The color scheme and fraction of lipid A (ϕ = 0.075) are the same as in Figure 2." } ]
30944027_Fig6
[ { "from": "human", "value": "Illustrate the image through a descriptive explanation\n<image>" }, { "from": "gpt", "value": "MIR2052HG regulates LMTK3 transcription by regulating EGR1 binding to its motif in LMTK3 gene. a, b EGR1 regulates LMTK3 expression in MCF7/AC1 (a) and CAMA-1 (b) cells. c The EGR1 binding sites at the genomic location of the LMTK3 gene locus are indicated in the diagram. d, e ChIP analysis demonstrates binding of EGR1 to LMTK3 gene locus in MCF7/AC1 (d) and CAMA-1 (e) cells. IgG serves as a control. Error bars represent SEM of two independent experiments in triplicate; **p < 0.01. f Dual RNA-DNA-FISH demonstrates that MIR2052HG transcripts (green signal) fail to localize to the LMTK3 gene locus (red signal) in EGR1 knockdown MCF7/AC1 and CAMA-1 cells" } ]
35408693_molecules-27-02294-f014
[ { "from": "human", "value": "Summarize the visual content of the image.\n<image>" }, { "from": "gpt", "value": "Chemical structures of EGFR inhibitors." } ]
34522326_ece37467-fig-0003
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "Examples of variation in staining quality among snake head region of interest. (a) Under‐stained specimen that is also distorted by inappropriate foam packing material (2 inch soft foam sheets, Uline, WI, USA). (b) Understained specimen that is well‐contrasted with packing peanuts as packing material. Note the high contrast (oversaturation) of the skeletal system and low contrast of soft tissues. (c) Moderately understained specimen packed in packing peanuts (30% recycled polystyrene, Uline, WI, USA). Note that the left venom gland was dissected before preservation. (d) Well‐stained specimen, with an overstained Harderian gland, packed in packing peanuts. The left Harderian gland was dissected before preservation. Specimen (a) is Xenopholis scalaris (UMMZ 246854), (b) Aparallactus capensis (UMMZ 61599), (c) Lachesis muta (UMMZ 248369), and (d) Oxyrhopus melanogenys (MUSM 37417). Specimens were stained in 1.25% Lugol's iodine. L = Lens, Hg = Harderian gland, Vg = Venom Gland [Correction added on 15 July 2021, after first online publication: Figure 3 caption has been corrected in this version.]" } ]
35540646_fig10
[ { "from": "human", "value": "Provide a brief description of the given image.\n<image>" }, { "from": "gpt", "value": "DSC curves of Ni-HTPB and Li-HTPB." } ]
33764625_ajt16581-fig-0001
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "miR‐21 is upregulated in murine heart allografts during chronic allograft vasculopathy (CAV). (A,B) Differentially expressed miRNAs detected using miRNA microarray analysis at 4 weeks (A) following murine cardiac allogeneic transplant compared with syngeneic transplant and at 8 weeks (B) following cardiac allogeneic transplant compared with syngeneic transplant. A common set of 17 miRNAs was upregulated at both 4 and 8 weeks post‐allogeneic transplant; the list is shown in (C), ranked by mean versus fold change. (D) Venn diagram showing the set of upregulated miRNAs at 4 and 8 weeks after murine cardiac allogeneic transplant compared with syngeneic transplant. For statistical analysis, R was used to detect miRNAs with different expression levels between study groups (n = 4 samples per group). The resulting p values <.05 were considered statistically significant. (E,F) miR‐21 expression by qRT‐PCR (E) and ddPCR (F) in cardiac grafts after syngeneic and allogeneic transplant at 4 and 8 weeks post‐transplant; statistical significance was determined using Student's t test with Welch's correction (*p < .05; **p < .01; at least n = 3 per group). (G) Quantification of miR‐21 in (H1–H4, I1–I4) is shown (at least n = 3 samples per group). (H1–H4, I1–I4) Representative images of in situ hybridization (ISH) of murine cardiac sections from syngeneic (H1–H4) and allogeneic (I1–I4) transplant for miR‐21 at 8 weeks post‐transplant (n = 3 per group). Staining is shown in purple, and white arrows indicate the presence of miR‐21. Original magnification: ×10 in (H1, H3, I1, I3), scale bar 300 µm; ×40 in (H2, H4, I2, I4), scale bar 100 µm. ddPCR, digital droplet polymerase chain reaction; miRNAs, micro‐RNA; nc miRNA, negative control miRNA antagomir; qRT‐PCR, real‐time quantitative reverse transcription polymerase chain reaction [Color figure can be viewed at wileyonlinelibrary.com]" } ]
30297604_molecules-23-02558-f003
[ { "from": "human", "value": "Narrate the contents of the image with precision\n<image>" }, { "from": "gpt", "value": "Fluorescence microscopic images: (A) treatment of MCF-7 cells with 25 (1 µM) and 26 (0.75 µM) for 24 h; (B) treatment of A2780 cells with 25 (1 µM) and 26 (1 µM) for 24 h; scale bar = 10 µm, AO and PI were used." } ]
35189814_Fig2
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "Histology of resected aneurysmal tissue. Hematoxylin and eosin stain of the excised aneurysmal tissue revealed bacterial colonies in the vascular wall tissue at (40× magnification) (A). The bacterial colonies are better seen at a higher power (400× magnification) (B). Gram stain of the tissue shows gram-negative bacteria (C)" } ]
34959380_pharmaceutics-13-02099-f003
[ { "from": "human", "value": "Describe the following image in detail\n<image>" }, { "from": "gpt", "value": "Visual predictive check (VPC) of isavuconazole plasma concentration versus time for the final model. The colored areas represent the 95% prediction intervals calculated on the 2.5th and 97.5th percentiles (blue areas) and on the 50th percentile (pink area) of simulated data. Continuous blue lines correspond to the 2.5th, 50th and 97.5th percentiles of the observed data." } ]
29946345_Fig5
[ { "from": "human", "value": "Examine the image closely and share its details\n<image>" }, { "from": "gpt", "value": "Knockdown of IMPDH2 in cells without cytoophidia affects proliferation rate. a Wild-type, mut-IMPDH2 Col_5 and mut-IMPDH2 Col_32 were transfected with Non-Target siRNA (NT) or 100 nM IMPDH2 targeting siRNA for 48 h and labelled with EdU and anti-IMPDH2 antibody. Proportion of EdU-positive cells is presented in the top of each panel. More than 1000 cells were counted and at least three independent experiments were performed for each group. b IMPDH1 and 2 protein levels in WT and mut-IMPDH2 Col_5 and Col_32 indicating a decrease in protein levels under increasing doses of siRNA for IMPDH2-Kd. c The relative IMPDH activity of cell lysates of wild-type and mutant cell lines. d Proliferation rate for each cell line in various conditions was normalized with Non-Target siRNA transfected groups. Cells were transfected with 100 nM IMPDH2 siRNA for IMPDH2-Kd and supplemented with a daily dose of 1 mM guanosine (Gua) or 1 mM GTP. Error bars means SD. Student’s t-test, ***P ≤ 0.001. e Intracellular level of GTP (standardized with ATP) of wild-type and mutant cells after transfection of Non-Target or IMPDH2 siRNA" } ]
27128436_pone.0153468.g006
[ { "from": "human", "value": "Narrate the contents of the image with precision\n<image>" }, { "from": "gpt", "value": "(a) Viable bacterial counts of 7-day biofilms after reaction with medicaments for 12 h. Biofilms were formed on polystyrene carriers for 7 days by growing S. aureus in TSB-G, then treating with VCM alone or combination with 16 μg/mL, 32 μg/mL, and 64 μg/mL baicalein for 12 h(* compared to the control group, P < 0.001, average of 3 experiments). (b) 7 day BF scanning by SEM (×8000) G: control group; H: 4 μg/mL VCM; I: 16 μg/mL CLR; J: 16 μg/ml CLR + 4 μg/ml VCM; K: 32 μg/mL baicalein; L: 32 μg/mL baicalein + 4 μg/mL VCM. (c) Seven-day BF scanning by CLSM (×400) A: control group; B: 4 μg/mL VCM; C: 32 μg/mL baicalein; D: 32 μg/mL baicalein + 4 μg/mL VCM." } ]
33212949_sensors-20-06567-f006
[ { "from": "human", "value": "Give a short and clear explanation of the subsequent image.\n<image>" }, { "from": "gpt", "value": "Flowchart of the straight motion constraint using Z gyroscope." } ]
23426738_BJOPHTHALMOL2012301525F1
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "(A) Photograph of a subject with the Argus II system showing the video glasses (a), the Video processing unit (b) and the inductive coil (c). (B) Subject showing the format for the letter identification tasks with a letter displayed on a monitor in white on black, Century Gothic font. The monitor on the side shows the real time map of the electrodes being stimulated in the array (A) and the camera view (V); note that the actual test is carried out in the dark. (C) Fundus photograph of the retinal stimulating array in situ. The optic nerve is indicated and the retinal tack that secures the electrode array is clearly visible. (D) Diagram illustrating the difference between the electrode activation maps under the ‘home use’ (standard) and ‘scrambled’ mode when the camera is viewing the letter L. In the scrambled mode, the spatial correspondence between a point's real position and the stimulation position on the array has been randomised. In this way, the patient does not receive spatial information but does receive non-spatial light detection information." } ]
28396517_F6
[ { "from": "human", "value": "Break down the elements of the image in a detailed manner\n<image>" }, { "from": "gpt", "value": "Oligomeric states of the WT and mutant MBP-CHIP by native gel electrophoresis Ten micrograms of WT and mutant MBP fusion protein was tested for migration on a 12% native-PAGE gel. Protein bands were visualized following Coomassie Blue staining." } ]
26494115_RRV063F1
[ { "from": "human", "value": "Relay a brief, clear account of the picture shown.\n<image>" }, { "from": "gpt", "value": "Kaplan–Meier curves for overall survival, disease-free survival, and local control." } ]
27579323_fig5
[ { "from": "human", "value": "Share a concise interpretation of the image provided.\n<image>" }, { "from": "gpt", "value": "Producing nearby solutions in TS." } ]
31262070_jcm-08-00952-f003
[ { "from": "human", "value": "Give a short and clear explanation of the subsequent image.\n<image>" }, { "from": "gpt", "value": "Comparison of median PFS between SDHD (n = 8) vs. SDHB (n = 5) patients (p = 0.014)." } ]
20122187_F1
[ { "from": "human", "value": "Write a terse but informative summary of the picture.\n<image>" }, { "from": "gpt", "value": "ROC scores distributions. (a) ROC scores distribution for the Irredundant Class and state-of-the-art methods. (b) ROC scores across families." } ]
18504316_fig2
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "Example dwell-time histograms of single channel recordings. (A) Dwell-time histogram of the closed states of a single MEC-4d/10d + MEC-2 + MEC-6 channel. (B) Dwell-time histogram of the open states of the same channel as in A. For optimal visual estimation of fit quality (Sigworth and Sine, 1987), dwell times are accumulated into logarithmic bins and displayed with a square-root ordinate. Solid lines are fits to the data with the sum of three exponential functions, dotted lines represent each exponential component." } ]
35068817_F1
[ { "from": "human", "value": "Summarize the visual content of the image.\n<image>" }, { "from": "gpt", "value": "Patient positioned prone on radiolucent head fixation frame in neutral position and intraoperative neuromonitoring connected" } ]
31221973_Fig3
[ { "from": "human", "value": "Walk through the important details of the image\n<image>" }, { "from": "gpt", "value": "A heatmap showing the results of the initial assessment by QSE. Note the assessment was conducted for the distinct laboratory areas, and some units work in a shared laboratory space. Each QSE encompasses multiple subdomains; percentage disruption for each laboratory was estimated by calculating the percentage of these subdomains that were impacted by Hurricane Maria" } ]
32713890_fig_002
[ { "from": "human", "value": "Explain the various aspects of the image before you\n<image>" }, { "from": "gpt", "value": "Normal anatomy of the internal thoracic venous system of a 5-year-old female mixed-breed dog. A, B) ventral volume-rendered multidetector-row computed tomographic (MDCT) images of the cranial vena cava (CrVC) showing in detail the variations of the caval insertion of the internal thoracic veins (ITVs): A) double caval insertion. B) Unpaired insertion with a single median trunk (empty arrow). C) Ventral volume-rendered MDCT image of the thoracic region showing a detail of the insertion of the intercostal veins (arrowheads) from the ventro-lateral inner surface of the thorax into the ITVs. Ventrally, the ITVs receive small perforating veins from the soft tissue of the pectoral region and thoracic mammary glands (not detectable under normal conditions because of the small dimensions of these vessel compared to the spatial resolution of the CT scan). St, Sternum; litv, left ITV; ritv, right ITV; lbt, left brachiocephalic vein; rbt, right brachiocephalic vein; arrow, entrance of the right ITV into the ventral surface of the CrVC." } ]
35009660_sensors-22-00111-f005
[ { "from": "human", "value": "Share a concise interpretation of the image provided.\n<image>" }, { "from": "gpt", "value": "TCM: Exercises performed with a typical compensatory movement (a) Prone-Rocking, (b) Bird-Dog and (c) Bent-over Rowing." } ]
35206351_ijerph-19-02163-f002
[ { "from": "human", "value": "Describe the image concisely.\n<image>" }, { "from": "gpt", "value": "Conceptual model of the experience of a caregiver caring for patients with HD." } ]
31178693_F4
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "Immunohistochemical characterization of c-Fos positive cells in ovBNST in THIP-treated mice. Immunohistochemical staining for corticotropin-releasing factor (CRF, green) in BNST sections of Somatostatin-tdTomato (red) mice revealed that 64% c-Fos-expressing cells in the ovBNST, activated by THIP treatment, also express CRF. (A) Triple fluorescence labeling of CRF (green), Somatostatin (red, Sst) and c-Fos protein (black nuclei) in the ovBNST at high magnification. Scale bar: 100 μm. aca, anterior commissure; ic, internal capsule. (B) In line with the previous experiment (Figure 3), THIP induced a robust c-Fos activation in the ovBNST. The total number of c-Fos+ cells in the ovBNST are given as individual data points with means ± SEM, n = 5 and 4 mice treated with saline vehicle (Veh) and THIP, respectively; **p = 0.01 (t-test). (C) A pie chart representing the fractions of CRF/c-Fos+ (green), Sst/c-Fos+ (red), CRF/Sst/c-Fos+ (orange) and non-identified c-Fos+ (gray) cells in THIP-treated mice (n = 4)." } ]
32979094_Fig1
[ { "from": "human", "value": "Offer a succinct explanation of the picture presented.\n<image>" }, { "from": "gpt", "value": "Optimized structures of the species involved in the hydrolysis of oxaliplatin. The included distances are given in angstroms" } ]
21735312_Fig6
[ { "from": "human", "value": "Explain the various aspects of the image before you\n<image>" }, { "from": "gpt", "value": "Experiment 3. Top panel: Observed mean difference limens (DLs) at stimulus onset asynchronies (SOAs) of 200 ms (circles) and 400 ms (squares) as a function of the number of intervals as reported by Drake and Botte (1993). The estimated reciprocal functions and their equations are inserted. Bottom panel: Observed mean DLs at SOAs of 200 ms (circles) and 400 ms (squares) as a function of the number of intervals as found in the present study. The estimated reciprocal functions and their equations are inserted" } ]
25551442_pone-0115941-g006
[ { "from": "human", "value": "Walk through the important details of the image\n<image>" }, { "from": "gpt", "value": "Effects of pH on NS3 binding to ssDNA. Increasing protein concentrations (from 0 to 10 µM NS3hel and 0 to 5 µM NS3FL) were used to compare NS3hel (A) and NS3FL (B) binding to a fluorescently-labeled ssDNA at pH 6.4 and 7.2 and to calculate the dissociation constants (Kd) between ssDNA and the constructs. Closed (pH 6.4) and open circles (pH 7.2) represent the mean of fluorescence anisotropy obtained in three independent experiments. Data were obtained at 25°C and assay buffers contained 25 mM MOPS-NaOH (pH 6.4 or 7.2), 2 mM MgCl2 and 25 nM of the fluorescently labeled ssDNA." } ]
17640274_fig02
[ { "from": "human", "value": "Characterize the image using a well-detailed description\n<image>" }, { "from": "gpt", "value": "Quantification of teichoic acids. Cell-bound LTA (A) or LTA in the supernatant (B) of S. aureus strains grown to logarithmic phase (log) or overnight (stat) was quantified by ELISA. The concentration of LTA in cell lysates or supernatants was normalized to cultures with an OD578 of 1. Organic phosphate was determined as a measure for WTA concentration (C). Data represent the means ± SEM of at least three independent experiments (***P < 0.001, unpaired, two-tailed t-test)." } ]
30956978_fig5
[ { "from": "human", "value": "Write an exhaustive depiction of the given image\n<image>" }, { "from": "gpt", "value": "Quantitative real-time PCR targeting SLC9A3. Fold change in SLC9A3 copy number relative to the endogenous reference gene ATP2B4 was compared for (a) fertile controls (N1–N32; set 1) and (b) CBAVD patients (P1–P29). Fold change was interpreted as normal (0.5–1.5, grey bar), loss (<0.5, black bar), or gain (>1.5, white bar). (c) Distribution of copy number variants in CBAVD patients and controls. White, grey, and black bars represent gain, no change, and loss of copy number, respectively." } ]
26937895_F4
[ { "from": "human", "value": "Clarify the contents of the displayed image with great detail\n<image>" }, { "from": "gpt", "value": "Correlation analysis of serum levels of HBsAg with HBV DNA in CHB patients at different phases defined by SS or DS. CHB = chronic hepatitis B, DS = = dual standard, ENH = HBeAg negative hepatitis, HBsAg = hepatitis B surface antigen, HBV = hepatitis B virus, IC = immune clearance, IT = immune tolerance, LR = low replicative, SS = single standard." } ]
22412439_Fap1
[ { "from": "human", "value": "Offer a succinct explanation of the picture presented.\n<image>" }, { "from": "gpt", "value": "The molecular structure of the title compound, with displacement ellipsoids drawn at the 50% probability level." } ]
35018725_jcsm12868-fig-0002
[ { "from": "human", "value": "Render a clear and concise summary of the photo.\n<image>" }, { "from": "gpt", "value": "Funnel plot. No statistically significant publication bias can be identified." } ]
34735694_Fig1
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "Proactive and Reactive Control on emotional distraction. Note. Example trial sequence with Color Stroop stimuli and Emotional Stroop stimuli. In 'proactive control on emotional distraction', control from the Color Stroop task modulates emotional distraction in the subsequent Emotional Stroop task and in 'reactive control on emotional distraction' control from the Color Stroop task modulates emotional distraction from the previous Emotional Stroop task." } ]
29322095_F5
[ { "from": "human", "value": "Give an elaborate explanation of the image you see\n<image>" }, { "from": "gpt", "value": "Comparison of OPO behaviors in different microcavities. (A) Representative primary Kerr comb from DASP-functionalized hybrid microcavities pumped at 1550 nm, with a spacing of ~3.8 nm (0.46 THz). (B) Output power in the first generated idler photon as a function of peak intensity in cavities of a DASP-functionalized silica microcavity with Q = 0.7 × 108 and a nonfunctionalized silica with Q = 1.0 × 108. The OPO threshold for DASP-functionalized silica microcavity was observed to be 0.88 mW, whereas a clear threshold value was not observed within the same experimental input power range for a nonfunctionalized silica microcavity." } ]
30161214_pone.0203307.g011
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "Potential adipose tissue (dark, resinite-like cell bond with cell sizes up to 60 μm) from close to the Oreopithecus-skeleton of Baccinello (Italy). A: Polished thick section, under oil immersion and 270x magnification. Reproduction of plate 16, Fig 4 published by Teichmüller [119]. B: Simplified drawing of the thick section above, highlighting the cell structure (in grey)." } ]
28939847_Fig5
[ { "from": "human", "value": "Offer a thorough analysis of the image\n<image>" }, { "from": "gpt", "value": "Treatment impact on protein expression. The expression of phospho-EGFR (Tyr1068) (182 kDa), phospho-AKT (Ser473) (63 kDa) and phospho-MEK1/2(Ser217/221) (52 kDa) was evaluated under the following treatment conditions: control; cetuximab 5 nM; pertuzumab 20 μg/mL; cetuximab 5 nM + pertuzumab 20 μg/mL; 10 Gy; 10 Gy + cetuximab 5 nM; 10 Gy + pertuzumab 20 μg/mL; 10 Gy + cetuximab 5 nM + pertuzumab 20 μg/mL. Ratios of phospho-EGFR, phospho-AKT and phospho-MEK to GAPDH expression (41 kDa) were calculated and are graphed as (protein-of-interest (POI)/GAPDH). (A) SQ20B. (B) SQ20B-CSCs. (C) FaDu. Statistically significant differences are expressed as *p < 0.05, **p < 0.01 and ***p < 0.001. Each experiment was performed in triplicate." } ]
30340515_Fig3
[ { "from": "human", "value": "Share a concise interpretation of the image provided.\n<image>" }, { "from": "gpt", "value": "Overview of the clinical, immunohistochemical, and molecular results. Abbreviations: mo.-months; N-no; Y-yes; yr.-years" } ]
35296333_Fig1
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "PMCT scan of a typical contact shot wound (1 = transverse view, 3 = longitudinal view) and a typical close-range/distant shot wound (2 = transverse view, 4 = longitudinal view). Note the hyperdense ring that is surrounding the outermost part of the contact shot wound channel (red arrows) but is absent from the close-range/distant shot wounds (yellow arrows). Three measurements were obtained from the scans (channel diameter = mean of green measurements; ring diameter = mean of orange measurements; ring thickness = mean of blue measurements); please find numerical values in Table 1 and Additional file 2: Table S2" } ]
30655470_fig2
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "(a) Photograph of the AGIPD 1 million pixel system at the SPB beamline before mounting to the experimental chamber. The sensitive area is split into four independently movable quadrants. (b) Wedge system of the bottom quadrants. (c) Cooling channels of a single cooling block before electroforming and milling connector feedthroughs. (d) 3D image of the pins inserted into the cooling channels to enhance the turbulence of the flow." } ]
31888060_materials-13-00124-f008
[ { "from": "human", "value": "Share a concise interpretation of the image provided.\n<image>" }, { "from": "gpt", "value": "Surface roughness values of the HfC, TiC, and HfC/TiC coatings." } ]
35194085_Fig2
[ { "from": "human", "value": "Explain the various aspects of the image before you\n<image>" }, { "from": "gpt", "value": "Representative images of FISH analyses of HEK293 cells, HT1080 cells, hiMSCs, and iPSCs that contained each HAC/MAC. (a) HEK293 cells that contained 21HAC1. Red: alpha satellite probe (p11-4) staining the centromere of Chr.13, 21, 21HAC1. (b) HEK293 cells that contained 21HAC2. Red: alpha satellite probe (p11-4) staining the centromere of Chr.13, 21 and 21HAC2; green: pCX-EGFP. (c) HEK293 cells that contained MAC2. Red: mouse cot-1 staining MAC2. (d) HEK293 cells that contained MAC4. Red: mouse cot-1 staining MAC4. (e) HT1080 cells that contained 21HAC2. Red: alpha satellite probe (p11-4) staining the centromere of Chr.13, 21, 21HAC1. (f) HT1080 cells that contained MAC4. Red: mouse cot-1 staining MAC4. (g) hiMSCs that contained 21HAC2. Red: alpha satellite probe (p11-4) staining the centromere of Chr.13, 21 and 21HAC2. (h) hiPSCs (201B7) that contained MAC6. Red; mouse cot-1 staining MAC6. Inset: enlarged images of each HAC or MAC." } ]
31875060_FI170228pt-1
[ { "from": "human", "value": "Write a terse but informative summary of the picture.\n<image>" }, { "from": "gpt", "value": "Classificação de Ciernye Mader para osteomielite quanto ao padrão de acometimento ósseo. Tipo 1, medular; tipo 2, superficial; tipo 3, permeativa estável; tipo 4, permeativa instável." } ]
34466670_f0005
[ { "from": "human", "value": "Characterize the image using a well-detailed description\n<image>" }, { "from": "gpt", "value": "Southern blot analysis demonstrates CGG repeat expansion in the LRP12 gene (A). Histopathological findings at age 80 years. In the biceps brachii muscle, modified Gomori trichrome staining demonstrates atrophic fibers with rimmed vacuoles (B). Electron microscopy reveals that a fibroblast adjacent to the degenerated muscles contains intranuclear inclusion (arrowhead) surrounded by amorphous rough halos without limiting membrane (C). High magnification of the area indicated by arrowhead in panel C demonstrates intermingled granulofilamentous profiles (D)]. Toluidine blue staining of the sural nerve indicates severe axonal loss (E) and p62-immunoreactive intranuclear inclusions (F). Electron microscopy shows identical intranuclear inclusions in the fibroblast (arrowhead) of the sural nerve as those in the biceps brachii muscle [low (G) and high (H) magnification]. Scale bars: 50 μm (B, E); 10 μm (F); 2 μm (C, G); 0.2 μm (D, H). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)" } ]
26705539_fig0030
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "MEG functions at the onset of mesendoderm differentiation but shows no effect on Nodal and Wnt signaling. (A) FACS analysis of T and EOMES in H9 hESCs differentiated in MEG->A-BVF, A-BVF, and delayed MEG+A-BVF (with MEG added on day 1 instead of day 0) conditions. (B) FACS analysis of SOX17 and FOXA2 in H1 hESCs differentiated for 7 days in AWS condition and MEG+AWS condition with MEG added on day 0 or day 1. Cells were plated at 1.5 × 105 cells/cm2. (C) Western blotting of Phospho-SMAD2 (P-SMAD2) in H1 hESCs pre-treated with DMSO and MEG in mTeSR1 medium overnight, followed by 0.5 hr treatment of Activin A (10 ng/ml) in RPMI-1640 medium. SMAD2/3 was used as a loading control. n = 3 independent experiments. (D) Western blotting of Phospho-SMAD2 (P-SMAD2) in H1 hESCs untreated or pre-treated with DMSO and MEG (10 μM) in mTeSR1 medium overnight, followed by treatment of Activin A (10 ng/ml) in RPMI-1640 medium with DMSO and MEG for various lengths of time. SMAD2/3 was used as a loading control. (E) Western blotting of Phospho-β-CATENIN (P-β-CATENIN) in H1 hESCs untreated (Control) or treated with MEG at 10 μM and 25 μM in mTeSR1 medium overnight. β-CATENIN was used as a loading control. n = 2 independent experiments." } ]
34526599_Fig3
[ { "from": "human", "value": "Relay a brief, clear account of the picture shown.\n<image>" }, { "from": "gpt", "value": "Percentage of variance explained by dimensions extracted by correspondence analysis." } ]
32432076_F3
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "(A) Cyclic voltammetry (CV) curves of Cu3P@P/N-C at a scan rate of 0.1 mV s−1 in the initial five cycles. (B) Cycling performance at a current density of 1 A g−1 and (C) rate performance of Cu3P@P/N-C and pure Cu3P. (D) Electrochemical impedance spectroscopy (EIS) curves of Cu3P@P/N-C at different cycles during the first 500 cycles. (E) Cycling performance at a current density of 5 A g−1 of Cu3P@P/N-C and pure Cu3P." } ]
20950415_F4
[ { "from": "human", "value": "Offer a succinct explanation of the picture presented.\n<image>" }, { "from": "gpt", "value": "Average E/E'ratio in subjects with or without insulin resistance or diabetes. Figure 3 illustrates the E/E'average ratio in subjects with or without insulin resistance (IR) or diabetes." } ]
29352112_Fig2
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "Direct contact with mOBs inhibits the bone-resorbing activity of mOCs. a A representative MIP image of bone-resorptive activity in skull bone tissue of a Col2.3-ECFP/TRAP-tdTomato mouse injected with a pH-sensing chemical probe, pHocas-3. Green, pHocas-3; cyan, mOBs expressing Col2.3-ECFP; red, mOCs expressing TRAP-tdTomato; blue, bone tissues (SHG). Scale bar, 50 µm. b, c Assessment of mOC bone-resorbing activity. b Areas containing mOCs were automatically binarized from the original images. Red, mOC areas; gray, regions outside the mOC areas. c Mean pHocas-3 fluorescence intensities were measured inside (pHocas-3 signal) and outside the mOC areas (pHocas-3 noise). The bone resorbing index (BRI) was the ratio of the pHocas-3 signal to the pHocas-3 noise. d, e Images processed for BRI calculations (d for the mOC indicated with white asterisk in the outlined region of a, and e for the mOC indicated with black asterisk in the region delineated with a dotted line in a). Scale bar, 20 µm. f, g Magnified MIP images from the region outlined in a and f, and the region delineated by the dotted line in a and g, captured at 0, 160, and 320 min (upper panels). The 3D images yielded by colocalization analysis (bottom panels). Scale bar, 20 µm. The contact areas were those where mOBs and mOCs colocalized and are shown in yellow. The filled arrowheads show areas of mOB–mOC contact. The open arrowheads indicate separated mOBs and mOCs. The actual BRI values are shown to the right of the images. h BRI of mOCs in contact, or not, with mOBs. Snapshot MIP images were collected from 14 independent experiments; n = 34 (mOCs in contact with mOBs), n = 67 (mOCs not in such contact). Data are presented as means ± SDs. ****p < 0.0001 (Mann–Whitney test)" } ]
31510661_btz322-F4
[ { "from": "human", "value": "Break down the elements of the image in a detailed manner\n<image>" }, { "from": "gpt", "value": "GkmExplain outperforms ISM at identifying GATA1 motifs. A gkmrbf SVM was trained as described in Section 6.1. The 400 positives in the held-out test set were scanned using 10 bp windows (the length of the GATA_disc1 motif). Windows containing a complete embedded GATA_disc1 motif were labeled positive. Windows containing no portion of any embedded motif were labeled negative. All other windows were excluded from analysis. Windows were ranked according to the total importance score produced by the importance scoring method in question, and auROC and auPRC were computed. The GkmExplain method outperforms ISM and SHAP on both metrics. The dashed black line shows the performance of a random classifier. See text for more details" } ]
35276951_nutrients-14-00592-f001
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "Adjusted beta coefficients and 95% CI for birthweight z-score in association with individual and subclasses of maternal plasma phospholipid PUFAs and PUFA ratios per standard deviation increase at four visits during pregnancy. AA, arachidonic acid; ALA, alpha-linolenic acid; CI, confidence interval; DHA, docosahexaenoic acid; DGLA, dihomo-gamma-linolenic acid; DPA, docosapentaenoic acid; DTA, docosatetraenoic acid; EDA, eicosadienoic acid; EPA, eicosapentaenoic acid; FDR, false discovery rate; GDM, gestational diabetes mellitus; GLA, gamma-linolenic acid; LA, linoleic acid; PUFA, polyunsaturated fatty acid; Δ5-desaturase, AA/DGLA; Δ6-desaturase, GLA/LA; Risk estimates were adjusted for maternal age (continuous), race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic, Asian/Pacific Islander), education (high school or less, some college/associate degree, 4-year college degree or higher), nulliparity (yes/no), pre-pregnancy body mass index (<25.0, 25.0–29.9, 30.0–34.9, 35.0–44.9 kg/m2), gestational weight gain up to the respective visit (continuous), gestational week at blood collection (continuous), and gestational age at delivery (continuous). * Significant associations after FDR adjustment (p < 0.05)." } ]
22368478_f7-sensors-12-00429
[ { "from": "human", "value": "Summarize the visual content of the image.\n<image>" }, { "from": "gpt", "value": "The estimated covariance of an endpoint of one line feature. Red line: estimated covariance in laser SLAM; Green line: estimated covariance in monocular SLAM; Blue lines: estimated covariance in MPEF-SLAM." } ]
24058439_pone-0070897-g005
[ { "from": "human", "value": "Clarify the contents of the displayed image with great detail\n<image>" }, { "from": "gpt", "value": "Alignment of CAMP factor 2 amino acid sequences from P. acnes type strain NCTC737 (type IA1; ST1; CC1) and P. humerusii strains HL044PA1, HL037PA2, HL037PA3 and P08. Overall identity between the homologues from these two species based on their protein sequence is 92%. The N-terminal putative signal sequence cleavage site occurs at the AHA-VE sequence (start residue position, 26)." } ]
34941131_F4
[ { "from": "human", "value": "Walk through the important details of the image\n<image>" }, { "from": "gpt", "value": "Comparison of change from baseline in the left ventricular mass index indexed using height2.7 (A) and body surface area (BSA) (B) between the two groups. The change was significantly higher in the amlodipine group compared to the bisoprolol group using both BSA (35 ± 34.2 vs 9.8 ± 35.9 gm/m2; P = .017) and height2.7 (14.5 ± 15.4 vs 4.1 ± 17 gm/m2.7; P = .03)." } ]
12698198_fig2
[ { "from": "human", "value": "Offer a thorough analysis of the image\n<image>" }, { "from": "gpt", "value": "Differential sensitivity among BRCA1-defective and BRCA1-competent cells to Dox. In (A) HCC1937 cells, (B) MCF-7 cells and (C) MDA-MB231 cells, the dose-related activity of Dox is shown. Interpolate logarithmic curve and the IC50 of cell growth are shown in each quadrant. In (D), the value of IC50 determined for each cell line is shown. ° and °°: P<0.02." } ]
29599977_f2-br-0-0-1051
[ { "from": "human", "value": "Describe the image concisely.\n<image>" }, { "from": "gpt", "value": "Structures, combination models with alkylglycerone phosphate synthase target and docking scores of isothiocyanate-temozolomide derivatives (S1-10). S, structural derivative; BITC, benzyl isothiocyanate." } ]
31091716_microorganisms-07-00131-f008
[ { "from": "human", "value": "Narrate the contents of the image with precision\n<image>" }, { "from": "gpt", "value": "The sfp1Δ/sfp1Δ mutant is resistant to macrophage-mediated killing. (A) C. albicans cells were cocultured with 2 × 106 macrophage cells for 20 min at an MOI of 1. Data were obtained from three independent experiments by analyzing at least 300 macrophages per well. (B) A total of 105 C. albicans cells were cocultured with macrophages for 16 h at an MOI of 1:10. The cell viability was determined by CFU counting. The results are presented as the mean ± standard deviation (SD) of five independent experiments. ** P < 0.01." } ]
30602038_F6
[ { "from": "human", "value": "Describe the following image in detail\n<image>" }, { "from": "gpt", "value": "Meta-analysis of the risk of post-treatment lesions after first treatment in HIV-infected versus -uninfected women by sub-group. Mixed/other indicates the use of different treatments, including cryotherapy, thermal ablation, or LEEP and/or other treatments. Abbreviations: +, positive; -, negative; CIN, cervical intraepithelial neoplasia; HIV, human immunodeficiency virus; HSIL, high-grade squamous intraepithelial lesion; LEEP, loop electrosurgical excision procedure; OR, odds ratio." } ]
23463837_F2
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "(A) Uncapsulated neoplasm situated in the subcutis (H&E, scanning view). (B) Proliferation of bland round to ovoid cells arranged in a concentric perivascular pattern and many thin-walled branching staghorn vessels (H&E, ×200). (C) Smooth muscle actin (SMA) immunoreactivity is observed in the concentric perivascular myoid cells (SMA, ×200). (D) Immunoreactivity for desmin was negative (Desmin, ×200). (E) CD34 highlilghted only the endothelium (CD34, ×200)." } ]
30726772_fig1
[ { "from": "human", "value": "Narrate the contents of the image with precision\n<image>" }, { "from": "gpt", "value": "Cumulative cancer-specific and competing mortality according to patient characteristics: (A) age; (B) gender; (C) surgery; (D) surgery; (E) tumor site; (F) tumor grade; (G) tumor size; (H) T stage (8th); (I) LN metastasis. LN, lymph node." } ]
26038763_fig1
[ { "from": "human", "value": "Give an elaborate explanation of the image you see\n<image>" }, { "from": "gpt", "value": "The restriction-digestion analysis of the 23S rRNA gene amplicons from two characterized strains of T. pallidum (Nichols and Street 14) and from T. pallidum samples showing the existence of the A2058G mutation in the majority of the samples." } ]
33580081_Fig4
[ { "from": "human", "value": "Illustrate the image through a descriptive explanation\n<image>" }, { "from": "gpt", "value": "Maize yield of milpa systems in the Western Highlands of Guatemala. Crop combinations are ordered by their mean yield. Significantly different groups after Dunn’s test are indicated with letters within the graphs. Crop associations codes are: M-P: Maize-Potato, M-B-S: Maize-Bean-Squash, M-B-P: Maize-Bean-Potato, M-B: Maize-Bean, M-F: Maize-Faba, M: Maize monocrop, M-S: Maize-Squash, M-B-F: Maize-Bean-Faba." } ]
35204872_children-09-00151-f001
[ { "from": "human", "value": "Render a clear and concise summary of the photo.\n<image>" }, { "from": "gpt", "value": "Patient flow chart. After applying the exclusion criteria, the data was divided into before and after COVID-19 and analyzed by age." } ]
29951594_nha-4-nha170036-g003
[ { "from": "human", "value": "Describe the following image in detail\n<image>" }, { "from": "gpt", "value": "Weight loss by the time restricted feeding group versus controls 1. 1All values reported as mean ± SEM. Data were included for 46 participants; means were estimated using an intention-to-treat analysis using last observation carried forward. Body weight remained stable during the 2-week baseline period (week B1 and week B2). Body weight decreased in the time restricted feeding group relative to controls during the 12-week intervention period (P < 0.001 for time × group interaction)." } ]
35539816_fig2
[ { "from": "human", "value": "Characterize the image using a well-detailed description\n<image>" }, { "from": "gpt", "value": "The capacity fade rate per cycle of the LiFePO4/graphite full cells aged at different discharge rates: (a) the whole aging process; (b) the first 100 cycles; (c) the 50th to the 500th cycles; (d) the 500th cycle to the end." } ]
33413422_Fig7
[ { "from": "human", "value": "Illustrate the image through a descriptive explanation\n<image>" }, { "from": "gpt", "value": "Multifactorial differential gene expression analysis using differentially expressed COVID-19 lung and nasal data. a Variance plot, b Sample to sample distance plot, c Principal component analysis plot, d Clustered heatmap of the count matrix of the normalized RNA-seq reads (top 50 genes) of the SARS-CoV-2 infected nasopharyngeal and lung samples. e Common dispersion plot or the biological coefficient of variation plot. Here we are estimating the dispersion. The square root of the common dispersion gives the coefficient of variation of biological variation. Here the coefficient of biological variation is around 0.8. f MA plot. Plot log-fold change against log-counts per million, with DE genes are highlighted. The blue lines indicate twofold changes. Red and blue points indicate genes with P-value less than 0.05. g Expression profiles of genes encoding Integrins. Log2 (fold change) values are considered as the expression values of the genes and represented in a color-coded scale; Color towards red indicating higher expression, while color towards green indicating little to no expression" } ]
33383713_genes-12-00033-f001
[ { "from": "human", "value": "Give an elaborate explanation of the image you see\n<image>" }, { "from": "gpt", "value": "Illustration of the different immune milieu for microsatellite instable (MSI) (A) and microsatellite stabile (MSS) (B) pancreatic cancer. The different number of immune cells especially of CD8+ and CD4+ T-cells, myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) in the tumor microenvironment of the two groups of pancreatic cancer is shown." } ]
23341886_pone-0051963-g001
[ { "from": "human", "value": "Break down the elements of the image in a detailed manner\n<image>" }, { "from": "gpt", "value": "Comparison of oxygen saturation and heart rate on D0 and 48 hours after SBP-AG (D2). On D0, oxygen saturation and heart rate were monitored immediately before initiation of bronchoscopy, during BAL, during SBP-AG, immediately after the procedure, and at discharge. On D2, hemodynamic monitoring was done immediately before bronchoscopy, during BAL, immediately after the procedure, and at discharge. Bars represent median with 25 and 75th percentiles for subjects challenged with RW (white), HDM (gray), CAT (black). Whisker lines represent 10 and 90th percentiles. *p<0.05 compared to value for respective allergen group immediately before procedure. NS indicates there were no significant differences among allergen groups for the indicated time point." } ]
34885211_cancers-13-06103-f001
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "Multivariable analysis in SweDCIS, including patient and tumor characteristics. Hazard ratios with 95% confidence intervals for risk of all ipsilateral breast events (TotBE) and invasive events (InvBE) after 10 years, using the data set with complete biosignature data, including those with positive or unknown margins (n = 582)." } ]
35564280_nanomaterials-12-01571-f004
[ { "from": "human", "value": "Describe the image concisely.\n<image>" }, { "from": "gpt", "value": "(a) The XPS survey spectra. The high-resolution XPS spectra of (b) the C 1s, (c) the Co 2p and (d) the O1s elements of ZIF-67-derived Co3O4." } ]
29253856_pbio.2004086.g002
[ { "from": "human", "value": "Share a comprehensive rundown of the presented image\n<image>" }, { "from": "gpt", "value": "Basal transcription levels and IFN-induced expression of genes related to PAMP sensing and IFN induction and response. Boxplots showing differential expression (log2FC) in response to IFN and basal transcription levels (expressed as FPKM) of genes associated with pattern recognition (sensors), downstream signal transduction (adapters), and transcription factors related to either IFN induction or response (transcription factors). Every ortholog for each gene is indicated with a dot coloured according to their presence in the DNA-, RNA-, or both DNA- and RNA-sensing pathways (S1 Data). FPKM, fragments per kilobase mapped values; IFN, interferon; log2FC, log2 fold change; PAMP, pathogen-associated molecular pattern." } ]
31443143_ijms-20-03964-f009
[ { "from": "human", "value": "Give a short and clear explanation of the subsequent image.\n<image>" }, { "from": "gpt", "value": "CAT and ACT from RR increased osteoblastic bone formation via BMP and IGF-I signal transduction pathways." } ]
25290918_pone-0109159-g004
[ { "from": "human", "value": "Portray the image with a rich, descriptive narrative\n<image>" }, { "from": "gpt", "value": "Live-cell imaging of both mutants GFP-CTDΔ723 −741 and GFP-CTDΔ714–722. COS-1 cells co-expressing either GFP-CTDΔ723 −741 (A) or GFP-CTDΔ714–722 (B), along with the ER/DsRed marker, were subjected to live-cell imaging combined with the in vivo membrane protease protection assay, as described above in Figure 3. The images shown herein are a representative of at least three independent experiments undertaken on separate occasions that were each performed in triplicate (n = 9)." } ]
33809848_sensors-21-02210-f014
[ { "from": "human", "value": "Create a compact narrative representing the image presented.\n<image>" }, { "from": "gpt", "value": "Received bit energy-to-noise power spectral density (Eb/N0) for the 4QAM modulation at 50 W throughout the day." } ]
28456660_fig0010
[ { "from": "human", "value": "Share a comprehensive rundown of the presented image\n<image>" }, { "from": "gpt", "value": "Home-cage social proximity interactions. RFID tracking of mice in multiple occupancy cages enables an estimate of social proximity scores. A) still from a video with overlay of RFIDs for individual animals; B) the base plate array recognises unique RFIDs and records animal locations concurrently; C) cumulative time spent in close proximity (<75 mm) during day and night for each pair of animals in the cage. In this instance, animals A and B spend less time interacting closely with animal C and this is more apparent at night." } ]
28785626_f0035
[ { "from": "human", "value": "Examine the image closely and share its details\n<image>" }, { "from": "gpt", "value": "VEGF production. Elisa test data: Light units (y-axis) were measured in a luminometer (Victor 3) operating at 425 nm wavelengths. VEGF quantities were determined on the basis of standard curve (CTR) obtained using a solution with known concentration of VEGF. The amount of VEGF secretion in the conditioned medium collected by the endothelial cells cultivated with the addition of soluble CD54 (A) and with the addition of CMP4 (B), was normalized to cell number (1.5 × 104 cells/mm2)." } ]
30863333_fig1
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "Spatial coding of touch at the fingers. Data retrieved from Tamè et al. (2011) study in which participants performed a speeded go-no-go task to indicate whether the target finger had been stimulated or not. Across conditions, the target finger was presented alone or concurrently with a masker (double simultaneous stimulation, DSS) on another finger (i.e., other finger of the same hand, homologous finger of the opposite hand, non-homologous finger of the opposite hand). Moreover, in different blocks, participants assumed different postures (i.e., hands palm down or hand palm up). Unfilled circles: Stimulation at the target finger; filled black circles: stimulation at the non-target finger. Bar plots show percent errors as a function of stimulation condition and hands’ posture. Error bars represent the standard error of the mean (±SEM). Adapted from Tamè et al. (2011). © 2011 by Elsevier. Permission for the use of the image has been obtained from the Elsevier." } ]
32010167_f5
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "Spatial expression of EjPI in single-flower and double-flower E. japonica by semi-quantitative RT-PCR. (A) Spatial expression of EjPI in double-flower E. japonica. (B) Spatial expression of EjPI in single-flower E. japonica. Sep, sepals; Pe-se, petaloid sepals; Pet, petals; Sta, stamens; Car, carpels; Fi, filaments; An, anthers." } ]
28725775_fig2-2374289516661559
[ { "from": "human", "value": "Explain the various aspects of the image before you\n<image>" }, { "from": "gpt", "value": "Career choice and satisfaction with income. Each symbol represents an individual medical specialty. The percentage of respondents who would choose their medical specialty is on the y-axis, and the percentage of respondents to the survey satisfied with their income is on the x-axis. The straight line is a linear regression of the data. There is no correlation between the percentage who would choose the same specialty and satisfaction with income. Adapted from Peckham, used with permission." } ]
19073590_F1
[ { "from": "human", "value": "Summarize the visual content of the image.\n<image>" }, { "from": "gpt", "value": "The PASTAA workflow." } ]
35009739_sensors-22-00198-f002
[ { "from": "human", "value": "Render a clear and concise summary of the photo.\n<image>" }, { "from": "gpt", "value": "The algorithm of FL for SS." } ]
28724951_Fig2
[ { "from": "human", "value": "Create a compact narrative representing the image presented.\n<image>" }, { "from": "gpt", "value": "Distribution of NT-proBNP concentration. A sex difference was evident in each category except 20 to <40 pg/mL." } ]
28235036_pone.0172773.g001
[ { "from": "human", "value": "Explain the various aspects of the image before you\n<image>" }, { "from": "gpt", "value": "Influence of cholesterol crystals (CHCs) on E. coli (Ec)-lipopolysaccharide (LPS)-induced cytokine responses. (A–E) Isolated monocytes were stimulated with CHCs (2mg/mL) for 20 hours. Interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-6, IL-10, and IL-8 in supernatants were measured after 20 hours of incubation, and are shown as mean±SD for experiments using 9 healthy donors. (F–J) Isolated monocytes were stimulated with Ec-LPS at two concentrations; 0.01 (low) and 1.0 (high) μg/mL in the absence (black circles) or presence (white circles) of CHCs (2mg/mL). Concentrations of IL-1β, TNF-α, IL-6, IL-10, and IL-8 in supernatants after 20 hours of incubation are shown as mean±SD for experiments using 4 healthy donors." } ]
35334685_micromachines-13-00390-f004
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "The primary fabrication process of the piezoelectric film sensor on GH4169 superalloy steel substrate: (a) polishing and cleaning of the substrate; (b) deposition of SiO2 insulating layer without a stainless-steel mask plate (SSMP); (c) preparation of NiCr bottom electrode film on SiO2 insulating layer; (d) the sputtering of the ZnO piezoelectric layer; (e) preparation of NiCr top electrode film on ZnO piezoelectric layer; (f) growing SiO2 protective layer film." } ]
27708740_F1
[ { "from": "human", "value": "Relay a brief, clear account of the picture shown.\n<image>" }, { "from": "gpt", "value": "Perioperative evolution of haemoglobin in revision knee replacements with and without transfusion. *statistically significant differences (p<0.001)." } ]
27051557_fig1
[ { "from": "human", "value": "Provide a brief description of the given image.\n<image>" }, { "from": "gpt", "value": "Mosaic triploidy case showing facial profile (a), flat rocker bottom foot ((b) clinical and (c) X-ray), and triploid metaphase cell (d)." } ]
32823715_materials-13-03584-f008
[ { "from": "human", "value": "Write a terse but informative summary of the picture.\n<image>" }, { "from": "gpt", "value": "Langmuir isotherm plot of Cd2+ adsorption on FA/H2SO4." } ]
28855521_Fig4
[ { "from": "human", "value": "Analyze the image in a comprehensive and detailed manner\n<image>" }, { "from": "gpt", "value": "Superconductivity in monolayer NbSe2 devices. a Temperature dependence of the longitudinal resistance R for sample A—a monolayer NbSe2 device. Upper left inset: Optical image of a typical graphene protected monolayer NbSe2 device. Lower right inset: Superconductivity in monolayer, 5-layer and 10-layer NbSe2 devices. b Superconductivity of sample A in different magnetic fields. c Temperature dependence of the upper critical field H c2. The solid line is the linear fit to H c2. d Voltage–current (V-I) characteristic at different temperatures on a logarithmic scale. The solid blue line indicates the Ohmic behavior at high temperature. The solid black line represents the expected V∝I 3 behavior at the Berezinskii-Kosterlitz-Thouless (BKT) transition. The inset shows the temperature-dependent exponent deduced from the power-law behavior, V∝I . As indicated by the red dashed line, α approaches 3 at T = 0.8 K" } ]
35517918_fig2
[ { "from": "human", "value": "Create a compact narrative representing the image presented.\n<image>" }, { "from": "gpt", "value": "(a) XRD patterns and (b) Raman spectra of the SLS-700, [Amim]Cl-700 and [Amim]LS-700; (c) XRD patterns and (d) Raman spectra of the [Amim]LS-X." } ]
33651127_Fig4
[ { "from": "human", "value": "Write a terse but informative summary of the picture.\n<image>" }, { "from": "gpt", "value": "Comparison of PBK model-predicted (continuous line) and experimentally determined (symbols, Cho et al. 2002) time-dependent cumulative urinary excretion of BCP-glucuronide in rats upon oral administration of 35.8 mg profenofos/kg bw" } ]
24843016_fig1
[ { "from": "human", "value": "Offer a thorough analysis of the image\n<image>" }, { "from": "gpt", "value": "Cooling mildly affected electrophysiologically recorded firing rates generated by auditory receptor neurons in response to sound. (A) Voltage traces at 29 and 21°C for one neuron (red and blue lines, respectively). Black horizontal lines mark time intervals of stimulus presentation; stimulus intensity as indicated. (B) Firing-rate as a function of sound intensity was well described by sigmoidal functions at both temperatures (same neuron as in A). The three sigmoidal parameters (saturation rate, sound level at half-maximum, and dynamic-range width) were extracted from fits to the experimental data. (C) Statistics of the measured temperature dependence, , were computed for several quantities x. For a population of nine receptor neurons all three parameters of the sigmoidal function, as well as the spike rate and slope at the cold half-maximum were temperature compensated (median , see also Figure 1—figure supplement 2 and Figure 1—figure supplement 3). DOI: http://dx.doi.org/10.7554/eLife.02078.003" } ]
35419025_F3
[ { "from": "human", "value": "Give an elaborate explanation of the image you see\n<image>" }, { "from": "gpt", "value": "KLF7 can regulate osteoclast differentiation. (A) Protein and mRNA expression levels of KLF7 and HO-1 after si-KLF7 and oe-KLF7 treatment. (B) TRAP staining showed that macrophage differentiation could be affected by silencing and overexpressing KLF7. (C) Changes of the expression levels of osteoclast markers after KLF7 silence and overexpression. *p < 0.05." } ]
27042642_fig4
[ { "from": "human", "value": "Summarize the visual content of the image.\n<image>" }, { "from": "gpt", "value": "Results expressed as percentages obtained through Boehm's validation." } ]
32648174_Fig3
[ { "from": "human", "value": "Walk through the important details of the image\n<image>" }, { "from": "gpt", "value": "Scatter plots displaying the relation between the physical similarity measures for the Arabic digits (PSA) and physical similarity measures for Mandarin digits (PSM) slopes. The top left-hand panel shows a scatter plot of how the participant slope values for PSM varied across the Mandarin and Arabic conditions – the positive correlation reflects the fact that the influence of PSM was the same both conditions. The top right-hand panel shows a scatter plot of how the participant slope values for PSA varied across the Mandarin and Arabic conditions – the scatterplot reveals the influence of PSA in the Mandarin condition was unrelated to that in the Arabic conditions. The bottom left-hand panel shows a scatter plot of how the participant slope values for PSM and PSA varied within the Mandarin condition. The bottom right-hand panel shows a scatter plot of how the participant slope values for PSM and PSA varied within the Arabic conditions" } ]
24623722_F1
[ { "from": "human", "value": "Provide a detailed description of the given image\n<image>" }, { "from": "gpt", "value": "Yeast two-hybrid screen design and results. (A) Schematic of primary screen strategy. In the forward screen, 188 MATα yeast, each transformed with a unique AD-Y construct (where Y is an ORFeome clone), are pooled, and an aliquot is deposited into 85 96-well plates. MATa yeast, each transformed with a unique DB-lamin A construct (41 in total), are also deposited in 96-well plates such that each well contains a unique DB-lamin A construct. Yeast are then mated in liquid YEPD medium (188 × 1). In the reverse screen, 41 MATα yeast, each transformed with a unique AD-lamin A construct, are pooled and deposited into 96-well plates. MATa yeast, each transformed with a unique DB-Y construct, are deposited into 147 96-well plates so that each well contains a unique DB-Y construct. Yeast are then mated in liquid YEPD medium (41 × 1). After the mating reaction, yeast are plated in duplicate on SC/-Leu/-Trp/-His +1 mM 3-AT to select for interactors and SC/-Leu/-His, +1 mM 3-AT +1 mg/L cycloheximide (CHX) to select for autoactivators. Primary positive colonies are consolidated into 96-well plates containing liquid SC/-Leu/-Trp media, cultured overnight, and then replated on selection plates for secondary phenotyping. Colony PCR was performed for each primary positive, and the results were sequenced. Each screen was repeated twice and identified 623 unique interactors. (B) Schematic of the retest strategy. Fresh archival stocks of 426 unique primary positives are retested against pools of AD/DB-lamin A. Of these, 337 retested positive and are considered verified interactors. (C) Venn diagram of the retest results. Of the primary positives, 49% from the forward screen retested and 83% of the primary positives in the reverse screen retested. Primary positives identified in both screens (forward or reverse) retested at higher rates than those only identified in a single screen." } ]
32905471_Fig3
[ { "from": "human", "value": "Present a compact description of the photo’s key features.\n<image>" }, { "from": "gpt", "value": "Plant parts used by herbalists in Kisumu East Sub County to manage diseases of the respiratory system" } ]
29755300_Fig7
[ { "from": "human", "value": "Render a clear and concise summary of the photo.\n<image>" }, { "from": "gpt", "value": "HPSEC profiles of gastric digestion of albumin from chicken egg white gels made at: (a) 90 °C, (b) 120 °C and (c) 140 °C" } ]
28476162_Fig7
[ { "from": "human", "value": "Offer a succinct explanation of the picture presented.\n<image>" }, { "from": "gpt", "value": "Schematic mechanism of anticancer activity of CSM bark extract" } ]
21935475_pone-0024826-g006
[ { "from": "human", "value": "Describe the following image in detail\n<image>" }, { "from": "gpt", "value": "Sleeping Beauty transposition assay in the H2K 2B4 cell-line. 500 ng of the Sleeping Beauty (SB) pT2/MONO-neo-eGFP plasmid and varying amounts of the SB100 transposase plasmid (0, 10, 50, 100, 250, 500, 1000 ng) was co-transfected into the H2K 2B4 cell-line. H2K 2B4 G148 resistant colonies were counted after 14 days of G418 selection. A significant increase in G418 resistant colonies was observed with cells co-transfected with 50,100, 250, 500 and 1000 ng of the SB100 transposase plasmid compared to the cells transfected with the transposon only, suggesting transposase mediated integration had occurred. *** p<0.001. One way ANOVA and Tukey test, N value of four. Error bars generated by SEM." } ]
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