Abstract:
The invention relates to a hand-held device for the dosed distribution of sprayable substances, especially medicaments to be inhaled, said device comprising a cartridge that can be displaced into the distribution-opening position by means of pressure in a housing, and a feeding mechanism moved by the opening course of the cartridge and used to register and display the distribution actuation carried out. Said feeding mechanism is arranged in the centre of a housing below the front wall of the cartridge, on the opening side, overlapping the cartridge valve tube. The aim of the invention is to provide one such hand-held device in a spatially favourable manner, with more reliability in terms of handling, and a simplified structure. To this end, a stepped feeding mechanism arranged in a plate-shaped housing is provided with control elements which rotate about the axis located in the longitudinal direction of the cartridge.

Description:
CROSS-REFERENCE TO RELATED APPLICATIONS  
       [0001]     The present application is a continuation of pending International patent application PCT/EP2005/054138 filed on Aug. 23, 2005 which designates the United States and claims priority from German patent applications Nos. 10 2004 054 179.5 filed on Nov. 10, 2004 and 10 2005 033 398.2 filed on Jul. 18, 2005. All prior applications are herein incorporated by reference.  
       FIELD OF THE INVENTION  
       [0002]     The invention relates to a hand-held device for delivering portions of sprayable substances, in particular inhaler medicaments, having a cartridge which is displaceable in a housing into the open position for delivery by pressing, and an indexing mechanism which is moved along with and by the cartridge during the opening stroke thereof, for registering and displaying delivery actuations which have been carried out, which indexing mechanism is disposed in a housing centrally below the opening-side end wall of the cartridge in a manner overlapping the valve tube of the cartridge.  
       BACKGROUND OF THE INVENTION  
       [0003]     Hand-held devices of the type in question are used in particular in medicinal aerosol therapy for the treatment of respiratory diseases. The pressurized cartridge mounted in the housing contains the medicament to be inhaled, with, in order to release or to eject the same, an axial displacement of the cartridge in the housing being required. For this purpose, the cartridge is equipped with a valve for discharging a predetermined quantity of medicament. The housing, which generally virtually completely surrounds the cartridge, furthermore has in a conventional manner a mouthpiece and/or an adapter for inhalation through the nose. It is necessary to provide the user with a counting device by means of which the consumed quantity of medicament or quantity of medicament still present in the cartridge can be displayed. Since a defined quantity of medicament is discharged upon each actuation of the cartridge, it is known to couple the counting device to the axial displacement of the cartridge in the housing for the discharging of medicament. Thus for example, there is known from FIGS. 8 and 9 of U.S. Pat. No. 6,431,168 a hand-held device which has an indexing mechanism centrally below the opening-side end wall of the cartridge. This indexing mechanism is matched in terms of diameter to the diameter of the cartridge. An electric contact is made during each opening stroke of the cartridge. These contact connections are counted and indicated in a display. This technically complex and therefore cost-intensive configuration requires an energy storage device in the form of a battery or the like, which furthermore, particularly when the hand-held device is used over a relatively long period of time, conceals the risk that the display of the indexing mechanism will fail due to discharging of the battery. This energy storage device is not necessary in another solution of the same US patent. There, a step-by-step indexing mechanism is provided, the construction of which is resolved in an extremely disadvantageous manner with regard to the space required and possibilities for cleaning.  
         [0004]     In view of the prior art described above, it is a technical problem of the invention to configure a hand-held device of the type in question in a spatially advantageous manner with a simplified construction and such that it is more reliable in terms of handling.  
       SUMMARY OF THE INVENTION  
       [0005]     This problem is solved first and foremost by the subject matter of claim  1 , this being based on a step-by-step indexing mechanism which is disposed in a plate-shaped housing and has indexing members which revolve about axes lying in the longitudinal direction of the cartridge. As a result of such a configuration, a hand-held device of the type in question is realised, which, because of the construction selected, is formed advantageously both with regard to the space required for the indexing mechanism and with regard to the possibilities for cleaning and, in addition, also with regard to the capability for being handled. A mechanically operating step-by-step indexing mechanism is provided which, owing to the selected location of the various indexing members, has an advantageous, space-saving constructional form. This is furthermore achieved in that—as furthermore preferred—the larger indexing members, in particular larger in diameter indexing members, of the step-by-step indexing mechanism are disposed concentrically with respect to a longitudinal center axis of the cartridge, which results in a further optimization of the construction space, since this enables the clearance which is present in any case below the cartridge in the hand-held device housing to be used to accommodate the step-by-step indexing mechanism. The step-by-step indexing mechanism is independent of an energy storage device and therefore provides a reliable display even over a relatively long period of use of the hand-held device. The function is ensured only by means of components which interact in a purely mechanical manner and which also furthermore preferably consist of the same plastics material. This makes a further contribution to simplifying production.  
         [0006]     The subject matters of the rest of the claims are explained hereinbelow in relation to the subject matter of claim  1 , but may also be important in their own right.  
         [0007]     It is thus furthermore provided that the step-by-step indexing mechanism has a ring which revolves concentrically with the valve tube, has an external scale and is rotated step-by-step by a toothed ring, which likewise revolves concentrically with the valve tube and is driven by the opening stroke of the cartridge, via a planet-wheel gear mechanism. The graduated ring is disposed under the opening-side end wall of the cartridge in overlap with the valve tube of the cartridge and, in this respect, preferably has a diameter matched to the diameter of the cartridge. This affords a large scale length, namely approximately corresponding to the circumference of the cartridge casing. The rotational movement of the graduated ring is derived from the relative displacement of the cartridge by the step-by-step indexing mechanism, the indexing finger of which operates on a track around the valve tube of the cartridge. The indexing finger in this case is preferably part of the integrally constructed step-by-step indexing mechanism and, in the operational position of the hand-held device, is supported in the region of the housing-side valve-tube receiving portion which at the same time forms the counter bearing for the valve tube with respect to the valve opening. A supporting portion for the indexing finger is formed in the housing. In the event of possible removal of the step-by-step indexing mechanism from the housing, the absence then of the supporting portion for the indexing finger means that an inadvertent, cartridge-independent actuation of the step-by-step indexing mechanism is not possible. It is furthermore provided that the planet wheel is mounted in a hole in the graduated ring and the associated sun wheel is seated on a disk having teeth on the lower side. This disk is in engagement with the indexing finger. A latching finger also engages in the toothing, in order to secure the rotational position of the disk that has been reached in each case. Sun wheel and toothed disk are preferably formed in one piece, with a coaxial alignment. The planet-wheel gear mechanism preferably passes on the angle of rotation to the graduated ring with a step-down ratio. Accordingly, for example, 200 or 300 stroke actions, matched to the volume of the cartridge, can be displayed on the graduated ring. It is furthermore preferred that the graduated-ring graduation, which is disposed on the outer circumferential surface of the graduated ring and runs in front of a viewing window of the housing, corresponds in each case to a plurality of individual rotary steps of the planet wheel. In this regard, it has furthermore proven advantageous that, with regard to the step-down ratio, an individual rotary step of the planet wheel takes place after a plurality of individual rotary steps of the sun wheel have taken place. The planet wheel is furthermore in engagement radially on the outside with a toothed ring. The latter has at least one slot extending from the lower peripheral edge in a direction obliquely upwards, for entry of the step-by-step indexing finger in order thereby to predetermine the indexing direction of the finger for the step-by-step continued rotation of the disk on the sun-wheel side. The step-by-step indexing finger or fingers may be part of a step-by-step indexing-finger star which has, for example, a central hub on which diametrically opposite step-by-step indexing fingers are integrally formed at a radial spacing therefrom. This step-by-step indexing-finger star is preferably formed in one piece. It preferably consists of a plastics material. The step-by-step indexing finger or fingers are directed obliquely upwards extending from the hub, the step-by-step indexing fingers furthermore moving in the direction of a plane perpendicular to the longitudinal axis during the delivery stroke of the cartridge. Accordingly, the step-by-step indexing fingers are stressed in the course of the delivery movement, i.e. in the course of the displacement of the cartridge along its longitudinal center axis. The valve tube of the cartridge passes through the hub of the step-by-step indexing-finger star. It furthermore serves in this case as centering means for the step-by-step indexing-finger star and, in addition, for the entire step-by-step indexing mechanism or the housing thereof. The hub of the step-by-step indexing-finger star is seated on the end surface of the supporting portion for the valve tube, which supporting portion is on the hand-held device-housing side. Accordingly, this supporting portion has a dual function, firstly as a release element in conjunction with the valve tube of the cartridge by the selected support for the valve tube causing a valve to be opened in the cartridge during the displacement of the cartridge. Further, the supporting portion has the function of an abutment for the step-by-step indexing-finger star. The step-by-step indexing-mechanism housing together with the further indexing members is displaced relative to the step-by-step indexing-finger star, with the step-by-step indexing fingers being moved into the plane oriented perpendicular to the longitudinal axis, which effects the described prestressing of the step-by-step indexing fingers and the indexing of the counting mechanism to the next position. After release of the cartridge, the latter hurries back into its basic position on account of the integrated valve spring, causing the step-by-step indexing-mechanism housing to lag behind because it is now not being acted upon. This is achieved by the prestressed step-by-step indexing fingers which automatically take up their original, obliquely upwardly directed position again and in the process press the indexing members and the step-by-step indexing-mechanism housing into their original position. Accordingly, the step-by-step indexing mechanism is decoupled from the cartridge with regard to being displaced back into a basic position. It has a restoring spring formed by the step-by-step indexing fingers. The entire step-by-step indexing mechanism together with graduated ring is preferably held in a housing, which in turn proves advantageous with regard to the desired cleaning of the housing. No gear mechanism parts whatsoever which can be damaged during cleaning, for example by means of brushes, are exposed. On the contrary, a compact, substantially closed constructional form is selected. In this regard, it is furthermore proposed that the step-by-step indexing-mechanism housing, which is configured as a flat plate, has a central hole for the passage of the valve tube, which hole widens at the cartridge end for the entry of a collar which protrudes on the opening side of the cartridge and behind the region of which a resilient latching between step-by-step indexing-mechanism housing and cartridge takes place. As a result of such a configuration, the step-by-step indexing-mechanism housing can be fixed on the cartridge centrally below the opening-side end wall in overlap with the valve tube of the cartridge. The resilient latching between step-by-step indexing-mechanism housing and cartridge may be selected in such a manner that it cannot be undone without a tool. In this case, the flat-plate-like step-by-step indexing-mechanism housing preferably has an outside diameter which corresponds to the diameter of the cartridge, and is accordingly, in the installation situation in the housing, placed fully in the shadow of the cartridge. The latching of the step-by-step indexing-mechanism housing to the cartridge enables step-by-step indexing mechanism and cartridge to be removed together from the housing, thus in particular for the purpose of cleaning the housing. The axial length of the entire step-by-step indexing-mechanism housing is furthermore preferably matched to the length of extent of the valve tube; accordingly, the latter furthermore remains enclosed in a protected position by the step-by-step indexing-mechanism housing in the position in which it is removed from the hand-held device housing. As an alternative, the step-by-step indexing-mechanism housing, which is configured as a flat plate, may be latched in the hand-held device housing in such a manner that it can still be displaced inwards by the opening stroke. Thus, for example during a first equipping of the hand-held device, the step-by-step indexing-mechanism housing can be pushed together with the cartridge into the hand-held device housing, whereupon the step-by-step indexing-mechanism housing finally engages behind a catch provided in the housing. The step-by-step indexing mechanism can furthermore be displaced inwards from this basic position via the stroke movement of the cartridge. In a development of the subject matter of the invention, a double latching of the step-by-step indexing-mechanism housing, which is configured as a flat plate, is provided in such a manner that, in addition to the latching to the collar of the cartridge, a second stronger latching takes place in the hand-held device housing. Before using for the first time, it is frequently necessary first to equip the hand-held device housing with the cartridge. In order to save the user a further working step, namely the equipping of the hand-held device with the step-by-step indexing mechanism, the latter may already be latched to the cartridge. Before using for the first time, the user fits the cartridge/step-by-step indexing mechanism unit into the hand-held device housing, after which the latching between step-by-step indexing mechanism and hand-held device housing engages. If the cartridge is pulled out of the hand-held device housing after this for cleaning purposes, the latching between step-by-step indexing-mechanism housing and cartridge collar is undone, the step-by-step indexing mechanism accordingly remaining in the hand-held device housing. In this regard, it has also proven advantageous if the stronger latching in the hand-held-device housing can itself be released after removal of the cartridge from the hand-held device housing. In an alternative configuration, it can be provided that the cartridge is blocked against being pulled off by means of retaining fingers which are formed pointing obliquely downwards in the hand-held device housing. Such a solution is advantageous in particular if no connection, in particular latching connection, is provided between the step-by-step indexing-mechanism housing and the cartridge. In this case, the retaining fingers are formed and oriented in such a manner that, at least during a first equipping, they can be overrun by the cartridge or the cartridge head, after which the retaining fingers enter in a blocking manner into a waist region of the cartridge formed behind the cartridge head. Finally, it is possible for the upper housing part of the hand-held device to be separable from the mouthpiece approximately in the region of the position of the plate-shaped step-by-step indexing-mechanism housing, in particular for the purpose of cleaning the hand-held device. In this case, the step-by-step indexing-mechanism housing can be latched in the mouthpiece and the cartridge can be secured in the upper housing part, for example by provision of the abovementioned retaining fingers. The separation made possible of the two housing parts enables easy cleaning, in particular of the bending region of the housing to which access is otherwise difficult. The compact, plate-shaped configuration of the step-by-step indexing-mechanism housing further facilitates this cleaning, since no awkward indexing members or the like are exposed in this case. The entire step-by-step indexing-mechanism housing may optionally also be removed from the mouthpiece and cleaned separately, for example under running water. 
     
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       [0008]     The invention is explained in more detail below with reference to the accompanying drawing which merely illustrates various exemplary embodiments. In the drawing:  
         [0009]      FIG. 1  shows, in perspective exploded illustration, the step-by-step indexing mechanism for the hand-held device according to the invention;  
         [0010]      FIG. 2  shows a cross section through the step-by-step indexing mechanism;  
         [0011]      FIG. 3  shows, in an illustration of a longitudinal section, the hand-held device in a first embodiment, with a step-by-step indexing mechanism (illustrated diagrammatically) latched to a cartridge;  
         [0012]      FIG. 4  shows a sectional illustration corresponding to  FIG. 3 , but relating to a second embodiment, in which the step-by-step indexing mechanism (illustrated diagrammatically) is latched to the housing;  
         [0013]      FIG. 4   a  shows a third embodiment in a sectional illustration according to  FIG. 4 , in which the cartridge is blocked in the hand-held device housing against being pulled off;  
         [0014]      FIG. 5  shows, in an illustration of a longitudinal section, the hand-held device in a further embodiment, after separation of an upper housing part from a mouthpiece. 
     
    
     DETAILED DESCRIPTION OF THE INVENTION  
       [0015]     The hand-held device  1  shown in  FIG. 3  in a diagrammatic sectional illustration is used for apportioned delivery of sprayable substances, in particular of inhaler medicaments.  
         [0016]     For this purpose, the hand-held device  1  has in first instance a hand-held device housing  2  into which a cartridge  3  containing the sprayable substance can be inserted. This cartridge  3  is axially displaceable in the housing  2 .  
         [0017]     In conventional manner, the cartridge head  4  has a central valve tube  5  extending coaxially with the cartridge  3 . A delivery of medicament is achieved via the said valve tube by an axial relative movement between cartridge  3  and housing  2 .  
         [0018]     The housing  2  is divided into two and substantially comprises two ring parts  6  and  7  which are disposed one above the other and of which the upper ring part  6  is formed in the manner of a shank and the lower ring part  7  has a mouthpiece  8  oriented approximately transversely with respect to the extent of the shank. The said mouthpiece can be closed by a covering cap (not illustrated).  
         [0019]     The valve tube  5  of the cartridge  3  is supported in an associated tubular supporting portion  9  within the lower ring part  7 , with axial movability of the cartridge  3  within the shank-like ring part  6  surrounding the cartridge  3 .  
         [0020]     The supporting portion  9 , which accommodates the valve tube  5  of the cartridge  3  in a clamping manner and is formed within the lower housing ring part  7 , is provided with a flow duct  10 , which is reduced in diameter compared with a portion accommodating the end of the valve tube and is connected in terms of flow to the valve tube  5 , that end of the flow duct  10  which faces away from the valve tube  5  pointing in the direction of the mouthpiece  8 .  
         [0021]     In the exemplary embodiment illustrated, the two ring parts  6  and  7  are connected to each other insertably. As an alternative, the two parts may also be connected to each other via a thread, for example via a coarse thread with a high pitch.  
         [0022]     The positioning of the cartridge  3  in the housing  2  is selected in such a manner that the cartridge head  4  is placed in the housing  2  approximately level with the connecting region between ring part  6  and ring part  7 .  
         [0023]     Centrally below the opening-side end wall of the cartridge  3 , a step-by-step indexing mechanism  11  is disposed in overlap with the valve tube  5  of the cartridge. This step-by-step indexing mechanism serves for registering and displaying the delivery actuations carried out, this taking place as a function of the opening strokes of the cartridge  3  that have been carried out.  
         [0024]     The step-by-step indexing mechanism  11  is shown in  FIG. 1  in a perspective exploded illustration. The central part of the step-by-step indexing mechanism  11  is a planet-wheel gear mechanism  12 , comprising a planet wheel  13 , a sun wheel  14 , which is seated on a disk  15  having teeth on the lower side, and a toothed ring  16  which interacts with the planet wheel  13 . The said toothed ring is formed on the inside wall of a ring  17  which is mounted non-rotatably and is in the form of a portion of a tube. The circumferential wall  18  of the ring  17  is passed through, in diametrically opposite regions, by slots  19  which extend obliquely upwardly directed in the indexing direction and end downwardly open towards the ring edge which faces away from the toothed ring  16 .  
         [0025]     The toothed ring  16  extends in the axial direction approximately over half of the height of the ring  17 , the circumferential wall  18  of which, which is stepped towards the ring end edge facing away from the toothed ring  16 , being formed such that it tapers radially.  
         [0026]     Below the toothed ring  16 , a latching finger  20  is integrally formed on the inside of the circumferential wall  18  of the ring  17 . With regard to a plan view of the ring, this latching finger is offset radially inwards with respect to the toothed ring  16 ; it correspondingly engages in a circular space drawn in radially inwards from the toothed ring  16 . Furthermore, the location of the latching finger  20 , which is formed elastically approximately in the vertical direction, is selected in such a manner that it engages approximately in a horizontal plane defined by the lower peripheral edges of the toothed ring  16 .  
         [0027]     The diameter of the disk  15  carrying the sun wheel  14  is selected to be slightly smaller than the inside diameter of the ring  17  in the region of the toothed ring  16 . Sun wheel  14  and disk  15  are preferably formed in one piece, from the same material.  
         [0028]     On the lower side of the disk  15 , a circumferential serration  21  is provided around the edge, in which serration the latching finger  20  of the ring  17  engages.  
         [0029]     The sun wheel  14  has a coarse toothing. Thus in the exemplary embodiment illustrated, eight sun-wheel teeth  22  are distributed uniformly over the periphery of the sun wheel  14 . During the course of the rotation of the sun wheel, these teeth  22  interact with the planet wheel  13 , which is disposed in the same plane between the sun wheel  14  and the toothed ring  16  of the ring  17 .  
         [0030]     The planet wheel  13  has a spindle  23  which protrudes upwards on one side, i.e. protrudes away from the disk  15  of the sun wheel  14 . This spindle is held rotatably in a hole  24  in the region of a collar  25 , which is directed radially inwards in the manner of a disk, of a graduated ring  26 . The graduated ring  26  is provided on its outer peripheral wall with a circumferential graduation  27 , the graduation corresponding in each case to a plurality of individual rotary steps of the planet wheel  13  conducting the graduated ring  26  onwards.  
         [0031]     The step-by-step displacement of the sun wheel  14  or of the disk  15  in one piece therewith takes place via step-by-step indexing fingers  28  formed in a manner such that they are deflectable resiliently, approximately vertically. These step-by-step indexing fingers  28  engage on the lower side in the serration  21  of the disk  15 .  
         [0032]     The step-by-step indexing fingers  28  are disposed diametrically opposite one another with regard to the main axis x of the step-by-step indexing mechanism  11  as a whole. For this purpose, in first instance a cylindrical central body in the form of a hub  29  is provided with a central, axial through hole  30 . The diameter thereof is slightly larger than the outside diameter of the valve tube  5  of the cartridge, which is to pass through this through hole  30 .  
         [0033]     On the bottom side, the hub  29  merges into a radially widened collar  31 . Integrally formed on the latter are guide portions  32  which protrude diametrically opposite one another in the radial direction and, in each case in the region of their free ends, form a guide pin  33  which is located in the associated slot  19  of the ring  17 .  
         [0034]     The step-by-step indexing fingers  28  are rooted in each case with a horizontal portion on the guide portions  32  with the guide pins  33  which protrude radially on the outside beyond the horizontal portion being left unaffected. The step-by-step indexing fingers  28  protruding from the horizontal portions extend in a direction obliquely upwards, for example enclosing an angle of 45 degrees with respect to the horizontal, matched to the slope of the slots  19  in the ring  17 . The step-by-step indexing-finger star formed in this manner bears the reference symbol S.  
         [0035]     The step-by-step indexing-finger star S, the ring  17  having the inner toothed ring  16 , the disk  15  which is in one piece with the sun wheel  14  and the graduated ring  26  are aligned concentrically with one another on the axis x, with the height of the ring  17  being selected in such a manner that both the step-by-step indexing-finger star S and the sun wheel  14  together with disk  15  are accommodated therein.  
         [0036]     The entire planet gear mechanism  12  and the step-by-step indexing-finger star S and the graduated ring  26  are accommodated in a cup-like step-by-step indexing-mechanism housing  34  with an outside diameter which is matched to the outside diameter of the cartridge  3 .  
         [0037]     The housing  34  has a circumferential wall  35 . The latter has a viewing window  36  through which the graduation  27  of the graduated ring  26  can be seen.  
         [0038]     The top of the housing  37  has a central break-through  38  which, in the embodiment shown in FIGS.  1  to  3 , is surrounded by latching spring tongues, which taper conically towards the interior of the housing, in the embodiment  39  shown in FIGS.  1  to  3 . The diameter of the break-through is matched to a diameter of a waist section  40  of a collar  41  which protrudes centrally above the opening-side end wall of the cartridge  3  and from which the valve tube  5  emerges.  
         [0039]     The housing base  42  is formed by a separate part. This is connected to the housing  34 , for example is welded to it or mounted on it via a press fit, with the previously described individual parts of the step-by-step indexing mechanism being accommodated.  
         [0040]     The plate-like housing base  42  has a central hole for the passage of the valve tube  5 . Also formed on the housing base  42  is a latching element  44  which, for securing the ring  17  in an oriented position, engages in a window-like recess  45  correspondingly formed in the circumferential wall  18  of the said ring.  
         [0041]     In the same angular region in which the fitting element  44  is disposed on the base, the outer circumferential wall of the housing base  42  has a clearance cut  46 . In the installation state, the latter is associated with the region of the starting cross section of the flow duct  1   0  in the lower ring-part housing  7 .  
         [0042]     The functioning of the step-by-step indexing mechanism  11  irrespective of the basic configuration still to be described with reference to  FIGS. 3 and 4  is as follows:  
         [0043]     The indexing members (step-by-step indexing-finger star S, ring  17 , disk  15 , planet wheel  13  and graduated ring  26 ) and the housing  34  with the housing base  42  are disposed on axes which extend in the longitudinal direction of the cartridge  3 . Thus, with the exception of the planet wheel  13 , all other components of the step-by-step indexing mechanism  11  are positioned on the longitudinal axis x-x of the cartridge.  
         [0044]     The step-by-step indexing mechanism  11  is disposed within the housing  2  in the shadow of the cartridge  3  and correspondingly concentrically with the valve tube  5 , to be precise in the construction space left between cartridge head  4  and supporting portion  9  of the housing  2 . The step-by-step indexing mechanism  11  is supported with the hub  29  of the step-by-step indexing-finger star S, which hub is mounted centrally in the indexing-mechanism housing  34 , on the end surface of the supporting portion  9  of the inhaler housing  2 . The central axis x of the step-by-step indexing mechanism  11  is assumed by the axis of the body of the cartridge  3 . The valve tube  5  passing through the hub  29  provides an additional means of centering the entire step-by-step indexing-mechanism unit.  
         [0045]     When an actuating stroke of the cartridge  3  is carried out together with an associated vertical displacement of the same in the direction of the supporting portion  9 , the indexing-mechanism housing  34  is carried along via the cartridge head  4 , with displacement of the housing  34 , the planet-wheel gear mechanism  12  and the graduated ring  26  relative to the step-by-step indexing-finger star S, which receives support on the supporting portion  9 . As a result, the step-by-step indexing fingers  28 , which are becoming stressed, with further assistance by the step-by-step indexing-finger star S sliding on in a rotating manner in the slots  19  in the circumferential wall of the ring  17 , effect a step-by-step rotary advance of the serrated disk  15 . In association with this, the sun wheel  14  rotates by the same angular amount. The step-by-step indexing fingers  28  move in this case out of the oblique orientation in the direction of a plane oriented perpendicularly with respect to the longitudinal axis x-x.  
         [0046]     Owing to the fact that the sun wheel  14  only has eight teeth distributed uniformly over the circumference, not every step-type rotational movement of the sun wheel  14  leads inevitably to a rotational movement of the planet wheel  13 . On the contrary, the rotation of the planet wheel  13  about its axis and an associated rotational displacement of the graduated ring  26  are carried out only after a plurality of individual rotational steps of the sun wheel  14 .  
         [0047]     According to the illustration in  FIG. 3 , the entire step-by-step indexing mechanism  11  can be fixed in a latching manner on the collar  41 , which protrudes on the cartridge-head side, by means of the housing  34 . In association with the housing-side viewing window  36 , the associated portions of the housing ring parts  6  and  7  likewise have viewing windows  47 ,  48  which, owing to the position selected, facing the mouthpiece  8  of the housing  2 , are located in the field of view of the user operating the hand-held device  1 . In order to insert the step-by-step indexing mechanism  11  in an oriented position, it is provided with a guide leaf  49  which protrudes radially from the housing  34  and engages in a vertical groove (not illustrated specifically) in the interior of the housing  2 , permitting the displacement travel during actuation of the stroke.  
         [0048]     The latching between step-by-step indexing mechanism  11  and cartridge  3  in the region of the collar  41  on the cartridge-head side is selected in such a manner that, if the cartridge  3  is removed from the housing  2 , the step-by-step indexing mechanism  11  is pulled out at the same time while remaining on the cartridge  3 .  
         [0049]     Alternatively, there is also the possibility, as illustrated diagrammatically in  FIG. 4 , for the step-by-step indexing mechanism  11  to be latched to the housing  2 . For this purpose, the step-by-step indexing mechanism  11 , in the course of a first fitting, moves over one or more radially inwardly protruding latching projections  51  of the housing  2 , under which latching projections  51  there then engage collar sections  52  protruding radially from the indexing-mechanism housing  34 .  
         [0050]     The latching projections  51  are positioned in their vertical orientation in such a manner that the vertical displaceability of the step-by-step indexing mechanism  11  is ensured during actuation of the stroke of the cartridge  3 .  
         [0051]     The configuration selected enables the latching projections  51  to form holding-down devices which retain the step-by-step indexing mechanism  11  in the housing  2  when the cartridge  3  is pulled off.  
         [0052]     In a further embodiment (not illustrated), a combination of the embodiments according to the illustrations in  FIGS. 3 and 4  can be provided, in which the step-by-step indexing mechanism  11  is fixed by latching on the collar  41  on the cartridge-head side by means of the latching spring tongue  39 . A preassembled cartridge/step-by-step indexing-mechanism unit of this type is introduced into the housing  2  before a first use of the hand-held device  1 , with collar portions  52 , which protrude radially on the indexing-mechanism housing  34 , running over latching projections  51  on the device-housing side, in accordance with the second exemplary embodiment, which results in a final fixing of the step-by-step indexing mechanism  11  in the housing  2 . This latching between step-by-step indexing mechanism  11  and housing  2  is selected to be stronger than the latching between step-by-step indexing mechanism  11  and cartridge  3 ; accordingly, a pulling-off of the cartridge  3  after being used for the first time results in the latching between cartridge  3  and step-by-step indexing mechanism  11  being undone. The reinsertion of the cartridge  3  is facilitated by a relatively weak latching-spring formation for interaction with the collar  41  on the cartridge-head side.  
         [0053]     Both in the case of the previously described embodiment and in the case of the embodiment according to the illustration in  FIG. 4 , there is the possibility of releasing the latching between device housing  2  and step-by-step indexing mechanism  11  after the cartridge  3  is removed from the housing  2  itself.  
         [0054]     The illustration in  FIG. 4   a  shows a further embodiment building on the configuration shown in  FIG. 4 . For further fixing of the cartridge  3 —in addition to a conventional clamping mounting of the valve tube  5  in the supporting portion  9  on the hand-held device-housing side—a blocking of the cartridge  3  in the region of the upper ring-part housing  6  is provided. Retaining fingers  55  which are directed obliquely downwards and are in one piece with the upper housing part  6  and from the same material protrude on the inner circumferential side of this upper housing ring part  6 . These retaining fingers  55  are positioned in such a manner that their free peripheral edges enter in a blocking manner, in the associated position with respect to the cartridge  3 , into the waist region of the cartridge  3 , which region is formed behind the cartridge head  4 , in order thereby to block the cartridge  3 .  
         [0055]     Furthermore, the retaining fingers  55  are formed in such a manner that they can be overrun by the cartridge head  4 , at least during a first equipping of the housing  2  with the cartridge  3 .  
         [0056]     The cartridge  3  is therefore secured on the hand-held device housing  2 , in particular on the upper housing part  6 .  
         [0057]     The illustration in  FIG. 5  shows a further embodiment. In this, the cartridge  3  is also secured on the upper housing part  6  by means of retaining fingers  55 . This upper housing part  6  can be released from the lower housing part  7 , which forms the mouthpiece  8 , the separation of the two housing parts  6  and  7  being undertaken approximately in the region in which the plate-shaped step-by-step indexing-mechanism housing  34  is positioned.  
         [0058]     In the assembled position of the two housing parts  6  and  7 , the latter are preferably latched, for which purpose one housing part has a latching nose and the other housing part has a correspondingly positioned latching receptacle.  
         [0059]     As a result of this separation which is made possible, an improved cleaning of the mouthpiece  8 , in particular of the bending portion having the stepped portion  9 , is achieved. This is furthermore facilitated by the entire step-by-step indexing mechanism  11 , which is formed as a compact subassembly, being removable in an extremely simple manner from the lower housing part  7  and therefore being able to be brought for separate cleaning. In the exemplary embodiment illustrated, no fixing means—such as, for example, latching projections  51  which interact with collar portions  52 , are provided. On the contrary, the entire step-by-step indexing mechanism  11  is fixed in the lower housing part  7  in interaction with the cartridge  3  in the position of use, with the step-by-step indexing mechanism  11  being aligned between the supporting portion  9  and the facing end surface of the cartridge head  4  (as also illustrated with reference to the embodiment shown in  FIG. 4   a ).  
         [0060]     Also in this embodiment, the step-by-step indexing mechanism  11  is secured against rotational displacement about the axis x-x by a positive connection between step-by-step indexing mechanism  11  and lower housing part  7 .  
         [0061]     All features disclosed are (in themselves) pertinent to the invention. The disclosure content of the associated/attached priority documents (copy of the prior application) is hereby also included in full in the disclosure of the application, also for the purpose of incorporating features of these documents in claims of the present application.