Abstract:
This liquid sample measurement device is provided with: a lancet mounting part to and from which a lancet device having a skin contact section for puncturing skin can be attached and detached; a sensor mounting part to which a biosensor, which is spotted with blood that comes out from the punctured skin, can be attached; and a measurement part that uses the biosensor attached to the sensor mounting part to measure the amounts of substances in the blood. The liquid sample measurement device includes a feature that makes it necessary to replace a lancet device that has been attached to the lance mounting part and has punctured skin, each time a lancet device is used to puncture skin.

Description:
PRIORITY 
       [0001]    This application claims priority under 35 U.S.C. §120 and 35 U.S.C. §365 of International Application PCT/JP2012/008311, with an international filing date of Dec. 26, 2012 which claims priority to Japanese Patent Application No. 2011-283196 filed on Dec. 26, 2011. The entire disclosures of International Application PCT/JP2012/008311 and Japanese Patent Application No. 2011-283196 are hereby incorporated herein by reference. 
     
    
     TECHNICAL FIELD 
       [0002]    The present invention relates to a liquid sample measurement device which measures biological information such as blood glucose concentration and lactic acid value from living subjects. 
       BACKGROUND ART 
       [0003]    An arrangement where a test strip port  101  and lancet device  102  are configured on a same end of a device main body  100 , as shown in  FIG. 13 , is well known, as the liquid sample measurement device. The liquid sample measurement device does not force users to perform complicated operations, but enables the users to perform an one-hand operation. Further, because a puncturing process and a measuring process can be performed closely, the liquid sample measurement device is characterized in realizing a small movement by the users (for example, see Patent Literature 1: Japanese Unexamined Patent Application Publication (Translation of PCT Application) No. 2007-532266). 
         [0004]    On the other hand, in medical institutions, disposal lancet devices are often used for puncturing in order to prevent blood infection. The disposal lancet devices cannot be reused after puncturing and are disposed (for example, see Patent Literature 2: Japanese Unexamined Patent Application Publication (Translation of PCT Application) No. 2005-518858 and Patent Literature 3: Japanese Unexamined Patent Application Publication (Translation of PCT Application) No. 2010-524558). 
         [0005]    Also, puncturing needle cartridges which are equipped to devices for puncturing have been disclosed. The puncturing needle cartridges have structures not allowing it to be reused after puncturing, and are disposed (for example, see Patent Literature 4: International Patent Application Publication No. WO/2006/118224). 
         [0006]    The above mentioned conventional liquid sample measurement device is arranged such that a depth controlling structure  103  of a lancet device  102  makes contact with a skin surface. 
         [0007]    The present invention is presented in considering the above mentioned problems, and has objective to provide a liquid sample measurement device having an element being replaceable, at which liquid sample such as blood of a living subject adheres. 
       SUMMARY 
       [0008]    A liquid sample measurement device of the present arrangement includes a lancet wearing part to which a lancet device is attachable, the lancet device including a skin contacting part for puncturing a skin; a sensor wearing part to which a biosensor is detachable, the biosensor on which blood from the skin by puncturing is deposited; a measuring section which measures an amount of a substance in the blood by using the biosensor being attached to the sensor wearing part. Each time when the lancet device performs to puncture the skin, it is needed to replace the lancet device which is attached to the lancet wearing part and which has punctured the skin. 
         [0009]    According to the above mentioned liquid sample measurement device, because an element at which the blood of a living subject adheres is easily replaced, safety is enhanced while convenience is enhanced. Further, according to the liquid sample measurement device, replacement of the element at which a liquid sample such as the blood of the living subject adheres can be encouraged. 
     
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         [0010]      FIGS. 1A to 1C  are view showing a configuration of a liquid sample measurement device of an embodiment of the present invention,  FIG. 1A  is a front view,  FIG. 1B  is a side view, and  FIG. 1C  is a lower side view; 
           [0011]      FIG. 2  is a view showing the liquid sample measurement device with a biosensor and a lancet device; 
           [0012]      FIG. 3  is an exploded diagrammatic view of the biosensor; 
           [0013]      FIGS. 4A and 4B  are a sectional view of the lancet device,  FIG. 4A  is a sectional view showing an embodiment as an example, and  FIG. 4B  is a sectional view showing a different embodiment; 
           [0014]      FIG. 5  is a block diagram of the liquid sample measurement device; 
           [0015]      FIG. 6  is a flowchart showing movements of the liquid sample measurement device; 
           [0016]      FIG. 7  is a block diagram showing the liquid sample measurement device of a second embodiment; 
           [0017]      FIG. 8  is a view showing an arrangement of the liquid sample measurement device of a third embodiment; 
           [0018]      FIG. 9  is a block diagram showing the same liquid sample measurement device; 
           [0019]      FIG. 10  is a flowchart showing movements of the same liquid sample measurement device; 
           [0020]      FIG. 11  is a view showing an arrangement of the liquid sample measurement device of a fourth embodiment; 
           [0021]      FIG. 12A  is a diagonal view showing a puncturing needle cartridge, and  FIG. 12B  is a block diagram showing relationship of a lancet wearing part configured on a device main body with peripheral elements; 
           [0022]      FIG. 13  is a view showing an arrangement of a conventional liquid sample measurement device. 
       
    
    
     DETAILED DESCRIPTION 
       [0023]    Hereinafter, embodiments of the liquid sample measurement device to which the present invention is applied are described with reference to the drawings. It will be apparent to those skilled in the art from this disclosure that the following descriptions of the embodiments are provided for illustration only and not for the purpose of limiting the invention as defined by the appended claims and their equivalents. 
       First Embodiment 
       [0024]      FIGS. 1A to 1C  are the view showing the arrangement of liquid sample measurement device of a first embodiment.  FIG. 1A  is the front view of the device main body  1 .  FIG. 1B  is the side view of the device main body  1 .  FIG. 1C  is the lower side view of the device main body  1 . As shown in  FIGS. 1A to 1C , on a front side of the device main body  1 , a display section  2  and an input section  3  are configured. On a back side of the device main body  1 , a finger position part  4  on which a user put a finger when holding the device main body  1  is configured. On a lower side of the device main body  1 , a sensor wearing part  5  and a lancet wearing part  6  are configured. As shown in  FIG. 2 , a biosensor  7  which is disposable is equipped on the sensor wearing part  5 . A lancet device  8  which is disposable is equipped on the lancet wearing part  6 . 
         [0025]    The biosensor  7  and lancet device  8  are disposable elements which are required to be replaced after the user uses them one time. These two elements are manually equipped on the device main body  1  by the user. Also, these two elements are detached from the device main body  1  by the user. 
         [0026]    The sensor wearing part  5  includes an arrangement which the biosensor  7  on which blood from a skin by puncturing is deposited can be equipped. The sensor wearing part  5  has an opening which extends to an inner side of the device main body  1  to accommodate the biosensor  7 . The opening has an inner diameter being equal to or slightly larger than an outer diameter of the biosensor  7 . The opening has a shape through which a part of the biosensor  7  can pass. 
         [0027]    An end of the biosensor  7  which is inserted to the sensor wearing part  5  is sustained by a connector  5   a  which constitutes a part of the sensor wearing part  5 . At this time, an opposite end (the other end) to the end sustained by the connector  5   a  sticks out of the device main body  1 . In this state, the blood is deposited on the other end of the biosensor  7 . When the biosensor  7  is disposed, the user holds the biosensor  7  and separates from the device main body  1  by pulling out of the sensor wearing part  5 . 
         [0028]    The lancet wearing part  6  includes an arrangement where the lancet device  8  including a skin contacting part for puncturing the skin is detachable. The lancet wearing part  6  is concaved in a direction towards the inner side of the device main body  1  for accommodating the lancet device  8 . The concave has a shape to accommodate a first body  8   a  of the lancet device  8 . This concave has an inner diameter being equal to or slightly larger than an outer diameter of the first body  8   a.    
         [0029]    The lancet device  8  is in a state where the lancet wearing part  6  is inserted and the end of the first body  8   a  is in contact with a bottom part of the concave. In this state, per the lancet device  8 , a periphery of the first body  8   a  is sustained by an engaging part, such as a rubber, which is configured on an inner wall of the concave. At this time, the opposite side of the first body  8   a  sticks out of the device main body  1 . Further, the lancet device  8  includes a second body  8   b  on the tip of the first body  8   a.  Puncturing is performed by contacting a tip of the second body  8   b  to the skin. When the lancet device  8  is disposed, the user holes the lancet device  8  and easily separates from the device main body  1  by pulling out of the lancet wearing part  6 . 
         [0030]    With the liquid sample measurement device, the biosensor  7  and the lancet device  8  as elements on which the blood adheres can be easily replaced by arranging in the way mentioned above. Therefore, the convenience is enhanced because measuring is continuously performed on a plurality of the subjects by replacing continuously the disposable elements. 
         [0031]    It is fine that a cover which is transparent or translucent to cover an opening part of the concave of the lancet wearing part  6 . The cover is detachable equipped with the device main body  1 . It is fine that the cover covers at least the opening part of the concave. For example, the cover can entirely cover the device main body  1 . Also, the cover can cover from a side surface having the lancet wearing part  6  to the input section  3 . Further, the cover can cover only the side surface having the lancet wearing part  6 . This cover is made of an elastic material such as rubber. When the lancet device  8  is not equipped on the device main body  1 , the cover covers the opening part of the lancet wearing part  6 . The lancet device  8  is equipped; this cover is pushed to extend towards the inner side of the concave. A part of this concave which is pushed to extend is between the inner wall of the concave and the lancet device  8 , and functions as the engaging part. 
         [0032]    Here, as shown in  FIG. 2 , the sensor wearing part  5  and the lancet wearing part  6  are configured such that the biosensor  7  and the lancet device  8  are configured adjacent to each other on the same side. In other words, a place for puncturing the skin and a place at which the blood is deposited are closely located in the liquid sample measurement device. This allows the user to puncture the skin by the lancet device  8  and spot the blood to the biosensor  7  smoothly with little movement in a short period of time. 
         [0033]    By the way, the locations of the sensor wearing part  5  and the lancet wearing part  6  are not limited to a horizontal alignment as shown in  FIGS. 1A to 1C . The locations of the sensor wearing part  5  and the lancet wearing part  6  can be a vertical alignment or a diagonal alignment, as long as on the same side surface. 
         [0034]    For example, when the user is a nurse who measures blood of a patient, the user holds by one hand the device main body  1 , and holds a finger of the patient by the other hand. Then, after puncturing by nearing the device main body  1  to the finger of the patient, the user lightly squeezes the blood by the hand holding the finger of the patient, while the device main body  1  stays in the same place. Then, depositing the blood can be performed by sliding the device main body  1  to locate the biosensor  7  at the place where the blood from the finger of the patient is squeezed. 
         [0035]    Further, the biosensor  7  and the lancet device  8  are closely configured on the same side surface, and are equipped to stick out from the device main body  1 . By this, it has an effect in reducing a chance of the blood squeezed from the skin by puncturing to be deposited by mistake on the device main body  1 . 
         [0036]    At this time, relationship of length for which the biosensor  7  and the lancet device  8  stick out of the device mail body is regulated, as follows. Namely, it is preferable that the tip of the biosensor sticks out longer than the tip of the lancet device  8 . This is related to a method for puncturing of the lancet device  8  being disposable. 
         [0037]    It will be discussed later, but puncturing is performed by urging a main body of the lancet device  8  onto the skin. It is same even when the lancet device  8  is equipped on the device main body  1 . Thus, the user performs moving the lower surface of the device main body  1  in a state in which the biosensor  7  and the lancet device  8  are equipped towards the subject for puncturing. 
         [0038]    At this time, the lancet device  8  is shorter because the second body  8   b  is slid into the first body  8   a.  For this reason, if the tip of the biosensor  7  exists closer to the skin side than the first body  8   a,  the biosensor  7  will collides with the skin strongly with momentum of puncturing and it will be possible that the biosensor  7  is damaged. Accordingly, the relationship in sticking out is defined. 
         [0039]    However, when the biosensor  7  and the lancet device  8  equipped on the device main body  1  are located with ample distance there between, it is fine that the tip of the biosensor sticks out longer than the tip of the first body  8   a  of the lancet device  8 . For example, when collecting blood of the tip of the finger by puncturing by using the lancet device  8  while stretching out the finger, it is fine as long as the biosensor  7  equipped on the device main body  1  is apart for a size of one finger from the lancet device  8 . By this, it is possible to avoid the collision of the biosensor to the finger of the patient when puncturing. 
         [0040]    Next, the finger position part  4 , as shown in  FIG. 4B  will be described. As shown in the figure, the finger position part  4  has a large shape of a basin towards the side of the lancet wearing part  6  of the device main body  1 . By this, the finger position part  4  is shaped to receive a force towards the lancet wearing part  6 . When the user holds the device main body  1 , the user put the finger on the finger position part  4 . When the user performs puncturing, the force is transmitted to the device main body  1  as the finger catches the basin. 
         [0041]    Next, the biosensor which is disposable and equipped to the liquid sample measurement device is described by referring to  FIG. 3 .  FIG. 3  is an exploded diagrammatic view showing the biosensor  7  equipped to the sensor wearing part  5  of the device main body  1 . 
         [0042]    The biosensor  7  includes an insulated substrate  11  (hereinafter simply “substrate  11 ”) made of polyethylene terephthalate or the like. A surface of the substrate  11  has a conductive layer. The conductive layer is made, for example, of noble metal, such as gold, and palladium, or conductive material, such as carbon and the like. Also, the biosensor  7  includes an insulated substrate  12  on an upper surface thereof. The substrate  12  has an air opening  13  at a center part thereof. Between the substrate  11  and the substrate  12 , a spacer  14  including a notch part is inserted. The biosensor  7  is made integrally of the substrate  11 , the spacer  14 , and the substrate  12 . 
         [0043]    A counter electrode  17 , a measurement electrode  18 , and a detection electrode  19  are formed by the conductive layer on the substrate  11  which is divided by slits. Each of the electrodes  17 ,  18 , and  19  are at least partially formed on the substrate  11 . Also, each of the electrodes  17 ,  18 , and  19  can be connected by lead wire to the liquid sample measurement device, in a state where the biosensor  7  is equipped on the device main body  1 . 
         [0044]    The spacer  14  is configured to cover the counter electrode  17 , the measurement electrode  18 , and the detection electrode  19  on the substrate  11 . A sample supply route  15  is formed by a notch part which is rectangular and which is on a front edge and a center of the spacer  14 . Also, sample liquid on a sample depositing part  15   a  of the sample supply route is suctioned towards an air opening  13  of the substrate  12  (in a direction of an arrow AR in  FIG. 3 ). 
         [0045]    The reagent layer  16  has a size and a shape to cover the counter electrode  17 , the measurement electrode  18 , and the detection electrode  19  which are exposed from the notch part of the spacer  14 . 
         [0046]    Oxidation reduction enzyme and electron acceptor are included in the reagent layer  16 . The oxidation reduction enzyme and the electron acceptor are dissolved and react with the liquid sample (in the present embodiment, blood from a human body) which is suctioned by the sample supply route  15 . After the reaction, the liquid sample measurement device electrochemically oxidizes the electron acceptor, which has been reduced. The liquid sample measuring device measures the biological information (in the present embodiment, the blood glucose concentration in the blood) in the liquid sample on the basis of the electric current obtained by the oxidation. This chain of the reaction is read by electric current with the electrochemical changes by the measurement electrode  18  and the detection electrode  19 . 
         [0047]    Also, an identifying part  20  is a member which identifies differences in output characteristic depending on kinds and production lot of the biosensor  7  by the device main body  1 . A combination of slit  21   g  and a slit  21   h  are configured at a part corresponding to the identifying part  20  of the counter electrode  17  and the detection electrode  19 . By this, the device main body  1  can identify the difference of the electrical output characteristic of the biosensor  7 . 
         [0048]    The counter electrode  17 , the measurement electrode  18 , the counter electrode  17 , and detection electrode  19  are arranged in the order from the sample depositing part  15   a  in the flow direction of the liquid sample (arrow AR) on the substrate of the biosensor  7 . The configuration of the counter electrode  17  and the measurement electrode  18  can be switched. 
         [0049]    Also, there is a prescribed distance between the measurement electrode  18  and the detection electrode  19  in the direction of the liquid sample flowing. By this, the detection electrode  19  can identify whether or not the liquid sample is surely and adequately suctioned. 
         [0050]    Next, the lancet device  8  which is equipped on the liquid sample measurement device is described by referring to  FIGS. 4A and 4B .  FIG. 4A  is a sectional view of the lancet device  8  which is equipped on the lancet wearing part  6  of the main body  1 . The lancet device  8  itself is categorized as a disposable type, as the user can use for puncturing. 
         [0051]    As described above, according to Patent Literature 2, of the lancet device  8 , a wing  33  of a piston  26  is on an upper edge  34  of a sleeve  22  (the second body  8   b ) by urging of a drive spring  31 . In this way, the piston  26  having a puncturing chip  29  is kept at a still position. 
         [0052]    When the user locates the end of the second body  8   b  on the subject for puncturing, and pushes a push element  23  (the first body  8   a ) to the subject for puncturing, a drive spring  31  is compressed until a surface-in-use  30  of the push element  23  abuts a push rod  27  of the piston  26 . When the push element  23  is further compressed, the wing  33  of the piston  26  is broken. Then, a fin  28  of the piston  26  is in contact with an internal limiting part  35  which limits depth of puncturing. In this state, the puncturing chip  29  passes through an opening  25  of a cap  24 . By this, the puncturing chip  29  comes down to a prescribed depth defined by a thickness of the cap  24 , and punctures the skin. In other words, puncturing is performed by locating the cap  24  on the skin and pushing from the other side towards the skin. Therefore, the cap  24  is a skin contact part which is arranged to be contact with a place for puncturing. 
         [0053]    Next, a returning spring  32  pulls back the piston  26  which includes the puncturing chip  29 . And then, the piston  26  moves to a second still position which is in the sleeve  22 . The lancet device  8  can not be reused, after the wing  33  of the piston  26  is broken. 
         [0054]      FIG. 4B  shows a convex belt  23   a  configured around the push element  23  of the lancet device  8 . The convex belt  23   a  is used for holding more strongly, when the lancet device  8  is equipped on the lancet wearing part  6 . In corresponding to the lancet device  8 , it is fine to include a convex part or a concave part, which is engaged with the convex belt  23   a,  on an inner wall of a concave of the lancet wearing part  6 . 
         [0055]    Next, constituent elements of the liquid sample measurement device is described by referring to  FIG. 5 .  FIG. 5  is a block diagram showing the liquid sample measurement device. As shown in  FIG. 5 , in the device main body  1 , the sensor wearing part  5 , the lancet wearing part  6 , a measuring section  36 , a controller  37 , the display section  2 , the input section  3 , a communication section  38 , and a recording section  39  are configured. 
         [0056]    Further, in the sensor wearing part  5 , the connector  5   a,  and the sensor wearing detecting section  5   b  are configured. The connector  5   a  is connectable to the counter electrode  17 , the measurement electrode  18 , and the detection electrode  19  of the biosensor  7 , when the biosensor  7  is equipped. The sensor wearing detecting section  5   b  detects whether or not the biosensor  7  is equipped on the sensor wearing part  5 . 
         [0057]    Instead of the sensor wearing detecting section  5   b,  it is fine to detect whether or not the biosensor  7  is equipped on the sensor wearing part  5  by a connection of the connector  5   a  to the biosensor  7 . 
         [0058]    Also, a lancet wearing detecting section  6   a  is configured in the lancet wearing part  6  to detect whether or not the lancet device  8  is equipped. 
         [0059]    The measuring section  36  detects blood glucose concentration of the blood which is deposited on the biosensor  7  equipped on the lancet wearing part  6  in response to an instruction from the controller  37 . For example, when the blood is deposited on the biosensor  7 , electric voltage or electric current is applied to each of the electrodes of the biosensor  7  via the connector  5   a.  The measuring section  36  measures the blood glucose concentration in the blood from electric voltage or electric current as a response of the application of the electric voltage. 
         [0060]    The controller  37  controls the liquid sample measurement device entirely. Specifically, information is input to the controller  37  from the sensor wearing detecting section  5   b,  the lancet wearing detecting section  6   a,  and the measuring section  36 . The controller  37  instructs the measuring section  36  and the display section  2 , and the communication section  38 , on the basis of the input information. 
         [0061]    The display section  2  works in response to the instruction from the controller  37 . The display section  2  displays the blood glucose concentration as the biological information measured by the measuring section  36 . Also, the display section  2  also displays various information for the user. 
         [0062]    The input section  3  is a device to which information such as an instruction of how to perform and identification number is input. The input section  3 , for example, is a button configured on the device main body  1 . Alternatively, the input section  3  is an optical reading device such as a barcode reader. Alternatively, the input section  3  can be an input by wireless communication or voice recognition such as RF-ID. The input section  3  of the present embodiment is equipped with a plurality of devices. Also, the information input to the input section  3  is transmitted to the controller  37 . 
         [0063]    The communication section  38  performs data transmission and reception with other devices, such as personal computers, by receiving the instruction from the controller  37 , by using the wireless or the wired communication means. For example, the communication section  38  transmits to other devices the identification number input to the input section  3  and the blood glucose concentration measured by the measuring section  36 . Also, the communication section  38  receives a list of the identification number from other devices. 
         [0064]    The recording section  39  receives the measurement result transmitted from the measuring section  36 , the information input by the input section  3 , the information received by the communication section  38 , and the like via the controller  37 , and records. The recording and playing the data to the recording section  39  is controlled by the controller  37 . 
         [0065]    The sensor wearing detecting section  5   b  and the lancet wearing detecting section  6   a,  when detecting that the biosensor  7  and the lancet device  8  are equipped respectively, transmits to the controller  37 . Detection means of equipping is, for example, an electrical switch which is mechanical and detects equipping by conduction of the electrical switch made by being pushed while the object is equipped. The detection means of equipping can be any means, as long as the means detects existence of the object and transmits, such as an optical sensor. 
         [0066]    The liquid sample measurement device like this includes arrangement, which requires the lancet device equipped to the lancet wearing part  6  and performing puncturing the skin, to be replaced after each time when puncturing the skin by the lancet device  8  is performed. The arrangement, as discussed hereinafter, includes not performs next measuring, until the lancet device  8  is replaced after the measuring section  36  measures. Also, the arrangement includes not recording the measured result to the recording section  39 , until the lancet device  8  and the biosensor  7  are replaced. The arrangement includes displaying on the display section  2  the measurement result and information persuading replacing the lancet device  8  and the biosensor  7 , and keeps displaying these information until the lancet device  8  and the biosensor  7  are replaced. 
         [0067]    Next, the movement of the liquid sample measurement device, as arranged in a way described above, is described by referring to a flowchart of  FIG. 6 . 
         [0068]    In step S 1 , the liquid sample measurement device starts processing measuring the blood glucose concentration in response to the operation of the user. For example, the process of measuring starts, when the user selects a menu of measuring the blood glucose concentration from a list of menu displayed on the display section  2  by using the input section. 
         [0069]    In step S 2 , the controller  37  processes identifying various identification. Here, the various identification includes three items which are user (measuring person) identification, patient (person to be measured) identification, and sensor (biosensor) identification. By identifying the various identification, the liquid sample measurement device can record “who”, “whom”, “by which biosensor”, and “when” measures. 
         [0070]    An example in which a barcode reader is equipped as the input section  3  for processing identifying the various identification is described. By the way, it if fine to employ the RF-ID as the input section  3  to read the various identification by close distance wireless communication. For example, when a chip for the RF-ID is enclosed in a name plate of the user or a bottle in which the biosensor  7  is enclosed, the process of identifying the various identification by reading it can be performed. 
         [0071]    First, when the user selects starting measuring the blood glucose concentration at the step S 1 , the display section  2  displays the instruction of reading the user identification. The user reads by using the barcode reader the barcode which is printed on the name plate and in which his/her information is recorded. The information of the user read by the barcode reader is transmitted to the controller  37 . 
         [0072]    The controller  37  reads from a list in which the information of the user is stored from the recording section  39 . The controller  37  confirms whether or not the information of the user is included in the list in which the information of the user is stored. At this time, the controller  37  communicates with a server outside, when the information of the user is not included in the list. Then, the controller  37  confirms whether or not the information of the user exists in the sever. 
         [0073]    Here, for example, the sever outside can be a computer which administrates users at each medical department at a hospital, or can be a sever that administrates the users in the hospital entirely. Other than that, the sever outside can be in any style as long as handling the information of the user, such as a sever administrating the user who measures in medical institutions. 
         [0074]    When the information of the user input by the input section  3  matches the information of the user stored in the recording section  39  or in the sever, the user identification is identified to proceed to the next identification. At this time, when the user identification is identified by communicating with the sever outside, the communication section  38  received the information of the user from the sever, and the information is added to the list of the recording section  39  by the controller  37 . 
         [0075]    On the other hand, when the information matching the information of the user input by the input section  3  does not exist in both the recording section  39  and the sever outside, the display section  2  displays a warning that the information of the user is wrong or that the user does not have authorization to measure. Then, it is prohibited from proceeding to a next process thereafter. 
         [0076]    When the user identification goes through in a normal way, the controller  37  identifies the sensor identification next. Identifying the sensor identification is performed by reading enclosing material such as a bottle in which the biosensor is enclosed, or the barcode which is printed on the biosensor itself. 
         [0077]    As the user identification, identifying the sensor identification having been read is performed by confirming whether or not matching with information (sensor identification) in a list prepared in the recording section  39 , or the sever outside. Further, for the biosensor  7  which is confirmed to match, the biosensor is confirmed whether or not a period of use thereof exceeds, by the controller  37  using the sensor identification. Further, at this time, it is fine that the controller  37  confirms whether or not there is recall information regarding the period of use and the like for the biosensor  7  having been identified, by inquiring the sever outside via the communication section  38 . 
         [0078]    When the biosensor  7  is confirmed to be valid for measuring by identifying the sensor identification, it proceeds to identifying patient identification next. On the other hand, when the information of the biosensor  7  is missing, or when the biosensor is identified to be invalid for measuring, the controller  37  displays a warning to use a different biosensor  7  by the display section  2 . The controller  37  renews the list of the recording section  39 , when receiving new information from the sever outside with regards to the sensor identification having been read. 
         [0079]    It is fine that the controller  37  encourages the user to confirm by showing the nitrification result by the display section  2  each time when identifying these identifications is completed. It is fine that the display section  2  switches displaying each time identifying the identification, or the display section  2  displays all together in line. 
         [0080]    When identifying the user identification and the sensor identification is completed in a normal way, the user is prepared. With the preparation up to here, identifying the biosensor  7  is completed for one user using one lot of the biosensor  7 . One lot of the biosensor  7  shows, for example, a plurality of sheets of the biosensor  7  enclosed in the bottle, the same characteristic, and the same production data. 
         [0081]    For example, it is possible for a nurse to measure continuously the blood glucose concentration of a plurality of patients in a room of a hospital. Also, there is a case in which measuring for the plurality of patients continuously by changing the biosensor  7  enclosed in the same biosensor  7 . In these ways, it is possible for the liquid sample measurement device to identify the patient identification, after identifying the user identification and the sensor identification once and omitting identifying thereafter. 
         [0082]    In this case, it is possible to make the user identification and the sensor identification having been identified to be valid for a prescribed period of time. In other words, the prescribed period of time elapses after identifying the user identification and the sensor identification is completed, measuring can not performed without the user identification and the sensor identification are identified again. The prescribed period of time is preset by the user, a part administrating the liquid sample measurement device, or the like. 
         [0083]    After identifying the user identification and the sensor identification is completed or selecting continuous measuring, which is described hereinafter, the display section  2  displays an instruction of reading the patient identification. Thereafter, it process to a patient&#39;s (subject person) preparation. 
         [0084]    The user uses the barcode reader as the input section  3  to read the barcode indicating particular information of the patient. The barcode is printed on a strap worn by the patient (subject person) around a wrist or the like, the patient name plate configured at a bedside of the patient, or a medical chart or the like given to the patient. 
         [0085]    The controller  37  reads out a patient table from the recording section  39 . The controller  37  confirms whether or not the information of the patient, which is read by the barcode, in the patient table which is read. When the information of the patient is not included, the controller  37  forms a recording area for the patient newly read from the patient table, and is prepared to record the measured value of the blood glucose concentration. After the preparation is completed, the controller  37  makes the display section  2  to display encouraging wearing the biosensor  7  on the sensor wearing part  5 , and the proceeds to the next step. 
         [0086]    At step S 3 , the liquid sample measurement device confirms whether or not the biosensor  7  is equipped. When the sensor wearing detecting section  5   b  detects that the biosensor  7  is equipped on the sensor wearing part  5 , the detection result is transmitted to the controller  37 . In response to this, the controller  37  displays this thing on the display section  2 . At this time, it is fine that the user confirms by seeing or the like validity of the biosensor  7  again by displaying the information of the biosensor  7  extracted in identifying the sensor identification at step S 2 . 
         [0087]    At step S 4 , the liquid sample measurement device confirms whether or not the lancet device  8  is equipped. The controller  37  inquires whether or not the lancet device  8  is equipped, after detecting that the biosensor  7  is equipped. The lancet wearing detecting section  6   a  confirms whether or not the lancet device is equipped on the lancet wearing part  6 , and transmits the result to the controller  37 . 
         [0088]    When the lancet device is not equipped, detecting by the lancet wearing detecting section  6   a  is continuously performed until step S 6 . When the lancet device  8  is detected to be equipped during step S 8 , a notice is sent to the controller  37  as an interrupting signal. 
         [0089]    Subsequently, the controller  37  instructs the measuring section  36  to measure the blood glucose concentration in step S 5 . The measuring section  36  applies electric voltage on the connector  5   a,  and starts monitoring response electric current. Then, a state of holding measuring is maintained, until a fact that the blood is deposited on the biosensor  7  is electrically detected via the connector  5   a  by it. 
         [0090]    At the same time, on the basis of the result for the inquiry to the lancet wearing detecting section  6   a  at step S 4 , the controller  37  makes the display section  2  display, as follows. 
         [0091]    When the lancet device  8  is detected to be equipped by the lancet wearing detecting section  6   a,  the display section  2  displays performing puncturing by the lancet device  8  having being equipped, and depositing the blood having been squeezed on the biosensor  7 . 
         [0092]    When the lancet device  8  is detected to be not equipped by the lancet wearing detecting section  6   a,  the display section  2  displays performing puncturing by a different lancet device  8 , and thereafter displays depositing the blood having been squeezed on the biosensor  7 . If, while displaying this, the notice by the interrupting signal from the lancet wearing detecting section  6   a  which is mentioned above is sent, it is switched to display performing puncturing by the lancet device  8  having been equipped. 
         [0093]    At step S 6 , the liquid sample measurement device measures the blood glucose concentration. The measuring section  36  applies the electric voltage to the connector  5   a  from getting into the state of holding of step S 5 . After the blood is deposited on the sample depositing part  15   a  of the biosensor  7  reaches the detection electrode  19 , the blood glucose concentration in the blood is measured by a measuring algorithm which is prescribed. Then, when measuring is completed, the measuring section  36  transmits the result of measuring the blood glucose concentration to the controller  37 . 
         [0094]    At step S 7 , the controller  37  makes the display section  2  display the blood glucose concentration which has been measured. Then, the controller  37  makes the display section  2  display instructing removing the biosensor, as the disposable element on which the blood is deposited, and display instructing disposing. 
         [0095]    Moreover, when the lancet device  8  is detected to be equipped at step S 4 , the controller  37  makes the display section  2  display encouraging removing the lancet device  8 . 
         [0096]    When a prescribed period of time has elapses (for example, 1 minute) after displaying at step S 7 , the controller  37  inquires the sensor wearing detecting section  5   b  whether or not the biosensor  7  is removed (step S 8 ). Further, when the lancet device  8  is detected to be equipped at step S 4 , the controller  37  inquires the lancet wearing detecting section  6   a  whether or not the lancet device  8  is removed. 
         [0097]    When either the biosensor  7  or the lancet device  8  is not removed, it proceeds to step S 9  to display encouraging removing by the display section  2 . And it proceeds to step S 8  again. 
         [0098]    By this, the controller  37  makes the display section  2 , which display the result of measuring by the measuring section  36 , display the result of measuring the blood glucose concentration and display encouraging replacing the lancet device  8  and the biosensor  7 . 
         [0099]    Both the biosensor  7  and the lancet device  8  are removed, not equipped, it proceeds to step S 10 . 
         [0100]    Step S 10  is a step in which the controller  37  records in the recording section  39  the blood glucose concentration which has been measured at step S 6  and to which the user add various information by associates to the blood glucose concentration. At step S 8 , after detecting the biosensor  7  and the lancet device  8  are removed, the display section  2  displays again the information of the patient, the result of measuring the blood glucose concentration, and the time of measuring, and displays encouraging the user to confirm. 
         [0101]    The display section  2  displays a list of various information which can be associated with the result of measuring the blood glucose concentration. By this, the user can select the various information to be associated by using buttons on the input section  3 . The various information is information with regards to lifestyle habits of the patient which is associated with the blood glucose concentration before meal, after meal, of before sleep for example. Other various information can be information by which the user (nurse) confirms a state of the patient, such as medication, medical examination, and other vital information. Further, other various information can be information which other engaged persons including doctors can share. Moreover, other than displaying the list, the display section  2  displays things that the user inputs by using the input section  3 . 
         [0102]    As described above, the controller  37  recognizes the user identification and the sensor identification which have been identified at step S 2  as the added information, with respect to the information in which the patient and the result of measuring the blood glucose concentration are associated with the various information. Such information is recorded as the result of measuring in a recording area of the recording section  39  corresponding to the patient identification. 
         [0103]    At step S 11 , the chain of processing in measuring the blood glucose concentration, which starts in step S 1 , ends. Here, it possible to select one of continuing or ending measuring the blood glucose concentration. When continuing measuring the blood glucose concentration is selected, it proceeds to identifying in step S 2 . At this time, it is possible to select one of identifying both the sensor identification and the patient identification and identifying (continuously identifying) only the patient identification. Therefore, in step S 2 , whether or not omitting identifying the sensor identification is displayed only proceeding from step S 11 , and user can select. 
         [0104]    In this regards, the user has to identify the sensor identification in the cases, as follows. For example, it can be a case in which the biosensor  7  which is used for measuring the blood glucose concentration next time is enclosed in a different bottle from the bottle used in a previous time. Also, it can be a case in which it is necessary to read the sensor identification to confirm the biosensor  7 . Further, it can be a case in which the biosensor  7  itself is determined to read the sensor identification one by one. 
         [0105]    When ending measuring the blood glucose concentration is selected, it is possible to select transmitting the result of measuring recorded in the recording section  39  to other devices such as the sever outside via the communication section  38 . At this time, it is possible that the controller  37  transmits from the communication section  38  not just the result of measuring last time, but the results of measuring in the past. 
         [0106]    When transmitting is completed, the liquid sample measurement device goes back to the normal menu before starting measuring the blood glucose concentration at step S 1 , and waits for the user instructing. Alternatively, the liquid sample measurement device intends to reduce power consumption by performing the minimum functions, and proceeds to a sleep mode as it is. 
         [0107]    Selecting each process in Step S 11  is performed interactively by the controller  37  which controls the display section  2  and the input section  3 . 
         [0108]    As shown in the chain of the process, the liquid sample measurement device prohibits from proceeding to the next step unless the user removes the biosensor  7  and the lancet device  8  each time when the blood glucose concentration is measured. 
         [0109]    Moreover, a disposable type of the lancet device  8  is used for puncturing. By this, the liquid sample measurement device cannot measure the blood glucose concentration next time by equipping again the lancet device  8  which has been used once. For this reason, the liquid sample measurement device makes it possible to replace the part, which is arranged to be in contact with the skin of the measuring subject person, each time when used. The liquid sample measurement device includes an arrangement which requires replacing the lancet device  8  which is equipped on the lancet wearing part  6  each time puncturing is performed and after used for puncturing the skin. Thus, according to the liquid sample measurement device, it is possible to encourage replacing the lancet device  8  as the element on which the liquid sample such as the blood or the like of the living subject is deposited. 
         [0110]    Also, of the liquid sample measurement device, the controller  37  controls the measuring section  36 . The controller  37  controls the measuring section  36  not to perform measuring for the next time until the lancet device  8  is replaced after the measuring section  36  measures. Therefore, according to the liquid sample measurement device, it is possible to replace the lancet device  8  as the element on which the liquid sample such as the blood or the like of the living subject. 
         [0111]    Likewise, the liquid sample measurement device cannot measure the blood glucose concentration for the next time with the biosensor  7  equipped thereon which has been used once. Therefore, the liquid sample measurement device makes the part, which is arranged to be contact with the subject person, replaced certainly when used once. The liquid sample measurement device like this includes an arrangement which requires replacing the biosensor  7  which is equipped on the device main body  1  each time puncturing is performed and after used for puncturing the skin. Thus, the liquid sample measurement device encourages replacing the biosensor  7  as the element on which the liquid sample such as the blood or the like of the living subject is deposited. 
         [0112]    Further, the liquid sample measurement device cannot record with the biosensor  7  and the lancet device  8  being equipped thereon which have been used once. For this reason, the liquid sample measurement device makes it possible to replace the part, which is arranged to be in contact with the skin of the measuring subject person, each time when used. The liquid sample measurement device like this includes an arrangement which requires replacing the biosensor  7  and the lancet device  8  each time puncturing is performed and after used for puncturing the skin. Thus, according to the liquid sample measurement device, it is possible to replace the biosensor  7  and the lancet device  8  as the elements on which the liquid sample such as the blood or the like of the living subject is deposited. 
         [0113]    As mentioned above, according to the liquid sample measurement device, in an arrangement in which the element on which the blood is deposited is replaceable, it is possible to render the user to replace. As a result, contamination and infection by the blood being deposited are prevented. 
         [0114]    Also, by equipping the lancet device  8  to the liquid sample measurement device, it is possible to decrease shaking when puncturing and to decrease pain of the user more than by using a very small lancet device  8  alone. In other words, when it is difficult to hold by hand the very small lancet device  8 , equipping the lancet device on the relatively larger lancet device  8  makes it possible to hold firmly. Thus, since it is easier to handle the lancet device  8  and to be held stably by hand, shaking and fluctuation less likely happen. As a result, since the vibration on the puncturing needle becomes small by decreasing the vibration of the lancet device  8  when puncturing, the pain caused by the fluctuation of the puncturing needle is decreased. 
         [0115]    As mentioned above, according to the liquid sample measurement device of the present embodiment, since it is easy to replace the biosensor  7  and the lancet device  8  which is disposable, the convenience is enhanced when replacing the element on which the blood is deposited. 
         [0116]    Further, the liquid sample measurement device cannot measure newly the blood glucose concentration unless the element such as the biosensor  7  and the lancet device  8  on which the blood is deposited is replaced. For this reason, it is possible to contribute in preventing the infection by the deposited blood. 
         [0117]    Additionally, according to the liquid sample measurement device, it results in decreasing the vibration when puncturing and decreasing burden of the user. 
         [0118]    Further, a spring for puncturing as an element which wears much is that of the lancet device  8  which is deposable. By this, the liquid sample measurement device does not have to fix the spring for puncturing within the device main body  1 . By this, since considering deterioration of the spring for puncturing because of multiple use of the spring for puncturing is not necessary, the liquid sample measurement device has merits of making the maintenance easy. 
         [0119]    Further, according to the liquid sample measurement device, the result of measuring the blood glucose concentration and encouragement of replacing the lancet device  8  and the biosensor  7  are displayed and kept displaying until replacing. Therefore, according to the liquid sample measurement device, it is possible to encourage replacing the biosensor  7  and the lancet device  8  as the elements on which the liquid sample such as the blood or the like of the living subject. 
       Second Embodiment 
       [0120]    Next, a second embodiment of the present invention is described by referring to the figures. For an ejecting mechanism of the biosensor  7  and the lancet device  8  configured within the liquid sample measurement device, it is different from the liquid sample measurement device of the first embodiment. By the way, for the liquid sample measurement device as in the second embodiment, the same configuration and movement as in the first embodiment is omitted by using the same symbols. 
         [0121]      FIG. 7  is a block diagram which shown the liquid sample measurement device of the present embodiment. The embodiment shown in  FIG. 5  is different in that a sensor ejecting part  41   a  is configured on a sensor wearing part  41 , and a lancet ejecting part  42   a  is configured on a lancet wearing part  42 . 
         [0122]    The sensor ejecting part  41   a  is a sensor ejecting mechanism which pushes out the biosensor  7  equipped on sensor wearing part  41  and separate from the device main body  40 . The sensor ejecting mechanism includes a pushing part and a drive motor. The pushing part pushes out an end of the biosensor from the inside to the outside of the device main body  40 . The drive motor drives the pushing part. The sensor ejecting part  41   a  ejects, as pushing out, the biosensor  7  from the sensor wearing part  41  by controlling the drive motor, when the controller  37  instructs to eject the biosensor  7 . 
         [0123]    The lancet ejecting part  42   a  includes a lancet ejecting mechanism which pushes out the lancet device  8  being equipped on the lancet wearing part  42 , and which separates from the device main body  40 . The lancet ejecting mechanism includes a pushing part and a drive motor. The pushing part pushes out an end of the lancet device  8  from the inside to the outside of the device main body  40 . The drive motor drives the pushing part. The lancet ejecting part  42   a  ejects, as pushing out, the lancet device  8  from the lancet wearing part  42  by controlling the drive motor, when the controller  37  instructs to eject the lancet device  8 . 
         [0124]    Because of these configurations, the next process is added to flow chart as  FIG. 6  shows. 
         [0125]    At step S 7 , at the same time or after measuring the blood glucose concentration on the display section  2 , instructing of removing the biosensor  7  and the lancet device  8  is displayed. At this time, the display section  2  encourages the user to input, by using the input section  3 , the instruction of removing the biosensor  7  and the lancet device  8  the text and illustration. 
         [0126]    Then, when the instruction of removing the biosensor  7  and the lancet device  8  from the input section  3  is input, the controller  37  instructs the sensor ejecting part  41   a  and the lancet ejecting part  42   a.    
         [0127]    As mentioned above, instead of the user holding and pulling out the biosensor  7  and lancet device  8  which have been used, the liquid sample measurement device automatically ejects. By this, it is possible to dispose, without the user touching, the biosensor  7  and the lancet device  8  on which the blood is deposited. 
         [0128]    The sensor ejecting part  41   a  and the lancet ejecting part  42   a  can be unitarily configured. The liquid sample measurement device ejects the biosensor  7  and the lancet device  8  at the same time, when the use instructs the biosensor  7  and the lancet device  8 . In this case, because equipping and ejecting the biosensor  7  are dominant, the lancet wearing detecting section  6   a  and confirming equipping the lancet in step S 4  can be omitted. 
       Third Embodiment 
       [0129]    Next, the liquid sample measurement device shown as a third embodiment of the present invention by referring to the figures. The liquid sample measurement device of the third embodiment is different from the liquid sample measurement device of the first embodiment because of mechanism which ejects the biosensor  7  and the lancet device  8 . The same configuration and movement as in the first embodiment is omitted by using the same symbols 
         [0130]      FIG. 8  is a view (front view) of the liquid sample measurement device of the present embodiment. Also, a block diagram of the liquid sample measurement device is shown in  FIG. 9 . The liquid sample measurement device is different from the liquid sample measurement device shown in  FIGS. 1A to 1C  because an ejecting lever  44  which the user operates is configured on a lower side of the device main body  43 . 
         [0131]    The ejecting lever  44  is slid by the user in a longitudinal direction of the device main body  43 . A sensor ejecting member  45   a  and the lancet ejecting member  46   a  are connected to the rejecting lever  44 . The sensor ejecting member  45   a  pushes out the biosensor  7  on the sensor wearing part  45 . The lancet ejecting member  46   a  pushes out the lancet device  8  on the lancet wearing part  46 . Therefore, when the user slides the ejecting lever  44 , the biosensor  7  and the lancet device  8  are ejected from the device main body  43 . 
         [0132]      FIG. 10  is a flowchart that shows the movement of the liquid sample measurement device of the present embodiment. 
         [0133]    At step S 12 , the liquid sample measurement device starts measuring the blood glucose concentration. The step is same as step S 1  in  FIG. 6 . 
         [0134]    At step S 13 , the controller  37  performs the identification process for various identification. The step is same as step S 2  in  FIG. 6 . 
         [0135]    At step S 14 , the controller  37  confirms whether or not the biosensor  7  is equipped. The step is same as step S 3  in  FIG. 6 . 
         [0136]    At step S 15 , the controller  37  starts holding measuring the blood glucose concentration. The step is almost same as step S 5  in  FIG. 6 . In this regards, the display section  2  is only different for displaying the instruction of depositing the blood on the biosensor  7 . 
         [0137]    Step S 16  is a step for measuring the blood glucose concentration. The step is same as step S 6  in  FIG. 6 . 
         [0138]    At step S 17 , the controller  37  makes the display section  2  display the blood glucose concentration being measured, and display the disposal by operating the ejecting lever  44  to remove the biosensor  7 . 
         [0139]    Then, the liquid sample measurement device asks ejecting (removing) at steps S 18  and S 19 , after confirming that the biosensor  7  is ejected (removed). This is same as steps S 8  and S 9  in  FIG. 6 . As mentioned above, the biosensor  7  and the lancet device  8  are ejected at the same time by operating the ejecting lever  44 . Thus, when the biosensor  7  is detected as being removed (ejected) on the basis of the signal of the sensor wearing detecting section  5   b,  the controller  37  assumes that likewise the lancet device  8  is removed. Also, when the biosensor  7  is detected as being removed on the basis of the signal of the lancet wearing detecting section  6   a,  it is fine that the controller  37  assumes that likewise the biosensor  7  is removed. Then, it proceeds to a next process of step S 20 . 
         [0140]    At step S 20 , the controller  37  records the result of measuring the blood glucose concentration on the recording section  39 . The step is same as step S 10  in  FIG. 6 . 
         [0141]    At step S 21 , the chain of the process ends. The step is same as step S 11  in  FIG. 6 . 
         [0142]    In this manner, unless the biosensor  7  and the lancet device  8 , which are the disposable elements, are removed, it works not proceeding to the next measuring of the blood glucose concentration by watching the ejection of the biosensor  7 . Therefore, according to the liquid sample measurement device, it is possible to replace the elements on which the liquid sample such as the blood of the living subject is deposited. 
         [0143]    As the device main body  1 ,  40 ,  43  can be equipped even though the shape of the lancet device  8  is different from the one in  FIGS. 4A and 4B , it is fine to include an adaptor between the lancet device  8  and the device main body  1 ,  40 ,  43 . The adaptor is detachable to the device main body  1 ,  40 ,  43 , and is fine either being disposable after used one time or being usable for multiple times. Also, the adaptor can be a part of the cover which covers partially or entirely the device main body  1 ,  40 ,  43 . For example, the cover covers at least the surface, on which the lancet device  8  is equipped, of the device main body  1 ,  40 ,  43 . Also, an end of the cover can extend from the upper part of the input section  3  to the upper part of the display section  2 . Further, the cover prevents fluid such as the blood from depositing directly on the device main body  1 ,  40 ,  43 . 
       Fourth Embodiment 
       [0144]      FIG. 11  is a view showing the liquid sample measurement device of a fourth embodiment. The liquid sample measurement device of the present embodiment includes a puncturing needle cartridge  56  which is disposable and conventional, as the lancet device. The puncturing needle cartridge  56  which is disposable is equipped to a device main body  51  instead of the lancet device which is disposable. Drive mechanism is equipped in the device main body  51  for puncturing. It is different from the liquid sample measurement device of the first embodiment for these issues. The elements of the present embodiment which constitute the liquid sample measurement device and which are not described are in the same configuration and for the same movement described in the first embodiment. 
         [0145]    As shown in  FIG. 11 , the liquid sample measurement device includes a display section  52  and an input section  53  on the front side of the device main body  51 . Further, the liquid sample measurement device includes a sensor wearing part  55  on which a biosensor  54  is equipped on the side of the device main body  51 , and a lancet wearing part  57  on which a puncturing needle cartridge  56  is equipped. Further, a puncturing depth adjusting part  58 , a puncturing button  59 , and an ejecting lever  60  are configured on the other side of the device main body  51 . The puncturing depth adjusting part  58  is mechanism which adjusts depth of puncturing when puncturing is performed by using the puncturing needle cartridge  56  equipped on the lancet wearing part  57 . The puncturing button  59  is button mechanism for puncturing by using the puncturing needle cartridge  56 . The ejecting lever  60  includes mechanism which ejects at least the puncturing needle cartridge  56  from the lancet wearing part  57 . 
         [0146]    The configuration and the movement of the biosensor  54  and the sensor wearing part  55  are same as the biosensor  54  and the sensor wearing part  5  shown in the first embodiment. 
         [0147]    The puncturing needle cartridge  56  is, for example, the one disclosed in aforementioned Patent Literature 4. A simplified view of the puncturing needle cartridge  56  is shown in  FIG. 12A . As shown in Patent Literature 4, a lancet main body  62  is embedded on the puncturing needle cartridge  56  in a hollow part inside a puncturing needle holder  61 . The lancet main body  62  is slidable in the hollow part of the puncturing needle holder  61 . A puncturing needle is configured (not shown in the figures) on a tip of the lancet main body  62 . The puncturing needle sticks out from an opening part  64  configured on a skin contacting part  63  of the puncturing needle holder  61  and performs puncturing against the skin.  FIGS. 12A and 12B  omit showing other configuration such as a protective cap of the puncturing needle in  FIGS. 12A and 12B . 
         [0148]      FIG. 12B  is a block diagram showing relationship between the lancet wearing part  57  on the device main body  51  and peripheral elements. In the lancet wearing part, a holder receiving part  65  and lancet main body receiving part  66  are configured. The holder receiving part  65  holds the puncturing needle holder  61  when the puncturing needle cartridge  56  is inserted. The lancet main body receiving part  66  sustains the lancet main body. Further, the lancet wearing part  57  includes an ejecting part  67  which is mechanism to eject the puncturing needle cartridge  56  from the lancet wearing part  57  by pushing out the puncturing needle holder  61  sustained by the holder receiving part  65 . Also, the lancet wearing part  57  includes a drive unit  68  which is mechanism for puncturing by driving the lancet main body  62  via lancet main body receiving part  66  by operating the puncturing button  59 . The drive unit  68  is arranged to adjust the depth of puncturing by changing sticking amount of the puncturing needle by operating the puncturing depth adjusting part  58 . 
         [0149]    When the user inserts the puncturing needle cartridge  56  in the lancet wearing part  57 , an end of the lancet main body  62  is in contact with the lancet main body receiving part  66  and sustained. When the user keep inserting the puncturing needle cartridge  56 , subsequently an end of the puncturing needle holder  61  is in contact with the holder receiving part  65  and sustained. From when the end of the lancet main body  62  is sustained by the lancet main body receiving part  66  to when the end of the puncturing needle holder  61  is sustained by the holder receiving part  65 , the lancet main body receiving part  66  is pushed by receiving a force from the user via the lancet main body  62 . 
         [0150]    A spring (not shown in the figures) configured on the drive unit  68  is charged (compressed) by the movement of the lancet main body receiving part  66  being pushed in. As a result, a drive force is stored in the drive unit  68  and the preparation of puncturing is completed, when the puncturing needle cartridge  56  is equipped on the lancet wearing part  57 . 
         [0151]    Thereafter, when the user instructs to perform puncturing by pushing the puncturing button  59 , the drive unit  68  performs puncturing by driving the lancet main body  62  by the drive force stored. 
         [0152]    When the user instructs to eject the puncturing needle cartridge  56  by operating the ejecting lever  60 , the ejecting part  67  works as pushing out the end of the puncturing needle holder  61  in order to release the sustention by the holder receiving part  65 . In other words, the puncturing needle cartridge  56  pushes out the puncturing needle holder  61  in a direction towards outside from the device main body  51  which is opposite to the direction of inserting the puncturing needle cartridge  56  to the lancet wearing part  57 . At this time, the lancet main body  62  is arranged to be pulled by the puncturing needle holder  61 . The sustention by the lancet main body receiving part  66  of the puncturing needle holder  61 , as the sustention by the holder receiving part  65  of the puncturing needle holder  61  is released. 
         [0153]    In this manner, the liquid sample measurement device of the present embodiment includes mechanism to drive the puncturing needle cartridge  56 . When puncturing by using the puncturing needle cartridge  56 , the user makes the skin contacting part  63  of the puncturing needle cartridge  56  in contact with the part for puncturing. The puncturing needle cartridge  56  cannot be reused after puncturing one time. Thus, the liquid sample measurement device of the present embodiment prevents infection due to the blood which is deposited because parts on which the blood is easily deposited are certainly replaced, each time after the blood glucose concentration is measured. 
         [0154]    The sensor ejecting member  45   a  can be configured on the sensor wearing part  55  as shown in the third embodiment. When the user operates the ejecting lever  60 , not only the puncturing needle cartridge  56 , but also the biosensor  54  is ejected by the sensor ejecting member  45   a,  and separated from the device main body  51 . Here, the sensor ejecting member  45   a  works as pushing the end of the biosensor  54  towards outside of the device main body  51   m  by synchronizing with the movement of the ejecting lever  60 . 
         [0155]    In all the embodiments described above, measuring the blood glucose concentration is described as an example, but not limited to it. For example, not only the blood glucose concentration, it is also fine as long as measuring by the biosensor equipped on the apparatus, such as value of lactic acid or cholesterol, and not limited to the subject person. 
         [0156]    Moreover, for the biosensor, it is not limited by the measuring method, but it is still fine as long as the biosensor is disposable, not only the electrochemical method, but also optical method and the like. 
         [0157]    The entire contents of Japanese Patent Application No. 2011-283196 (filed on Dec. 26, 2011) is incorporated herein by reference. 
         [0158]    The aforementioned embodiment is an example of the present invention. For this, the present invention is not limited to the aforementioned embodiment, but can have different embodiments. Needless to say, it is possible to make various modifications depending on the designs, as long as the modifications do not deviate from technical ideas of the present invention. 
       INDUSTRIAL APPLICABILITY 
       [0159]    The aforementioned liquid sample measurement device can be useful for a heath care monitoring apparatus, and the like, which measures body fluid.