Abstract:
This invention relates, e.g., to a method for expanding mammalian acinar cells, comprising culturing the cells in a cell culture system comprising a cell culture medium and a cell attachment surface, under conditions wherein the acinar cells undergo a 3-4 fold expansion together with transdifferentiation into a modified cell phenotype (IP cells) showing characteristics of acinar cells and liver cells. The invention also relates to a method for transforming these IP cells to insulin-producing cells in vitro, comprising culturing the cells in a novel, defined medium. Also disclosed are suitable culture media for performing these methods, isolated cells having the phenotype of IP cells and/or produced by these methods, and kits for performing the methods.

Description:
[0001]     This application claims the benefit of provisional application 60/384,000, filed May 28, 2002, which disclosure is incorporated by reference in its entirety herein. 
     
    
     BACKGROUND OF THE INVENTION  
       [0002]     1. Field of the Invention  
         [0003]     The invention relates to compositions and methods whereby, e.g. human pancreatic acinar cells are cultured under conditions that support expansion and transdifferentiation into glandular epithelial cells and subsequently into insulin-producing cells.  
         [0004]     2. Background Information  
         [0005]     The potential benefits of taking insulin-producing cells from organ donors and transplanting them into insulin-dependent, Type I diabetic patients is clear. In the Edmonton clinical trials, many patients have lived free from the delivery of exogenous insulin for approximately 2 years after being transplanted with intact islets from organ donor sources. However, current technology requires two organ donor pancreata to generate a sufficient number of islets (about 1 million islets, comprised of about 1,000 cells each) to transplant into one diabetic patient for cellular therapy. Thus, there has been emphasis in the diabetes field to identify new sources of insulin-producing cells for transplantation. Many avenues are being explored, including expansion of islets after harvest and before transplantation and the generation of new islets from stem-like cells derived from the bone marrow, or from precursor cells located in the pancreas. The challenges presented by these approaches are related to maintenance of function of islets over long periods of culture, and of the relative rarity of stem-like cells that can be harnessed for insulin production from the bone marrow and pancreas. The ductular precursor stem-like cells derived from the pancreas are reported to be more efficient than bone-marrow derived cells at differentiation into insulin-producing cells, and this may reflect their site of origin (i.e., pancreas) where they are certainly exposed to many differentiation signals related to the pancreatic microenvironment. The most abundant cell type in the pancreas is the acinar cell, which comprises about 85% of the pancreas. The acinar cells serve to produce and secrete digestive enzymes and, like islet cells, arise during development from the ductular cell compartment.  
         [0006]     There have been reports that acinar cells, when cultivated in vitro, especially under conditions of stress, can undergo a ‘transdifferentiation’ into a cell type that resembles ductular cells, as determined by expression of CK19, CK7, and carbonic anhydrase (all reputed by the authors to be markers of duct cells) (Kerr-Conte, 1996; WO 02/29010 A2), Hall et al., 1992). Furthermore, Bouwens et al. (1998) have shown in vivo, in a model of pancreatic duct ligation, that acinar cells in the ligated portion of the pancreas undergo transdifferentiation into cells with a ductular phenotype. Further work has suggested that insulin-producing cells can be produced upon further differentiation of the duct cells in the ligated portion of the pancreas. The acinar cells are also reported to be of limited survivability in primary culture, with some culture conditions leading to loss of at least 50% of cells within a week. While primary duct cells have been demonstrated in vitro to convert into insulin-producing cells under some culture conditions (e.g. Bonner Weir, 2000, U.S. Pat. No. 6,011,647), there are no reports of cells that arose from acinar cells in vitro differentiating further to produce islet-like cells.  
         [0007]     Prior to the development of the present system, primary pancreatic acinar cells were expanded without differentiation into insulin-producing cells, either in serum-containing medium (undesirable both because of the risk and the uncertainty associated with the use of serum), or in complex serum free media formulations. Likewise, primary pancreatic acinar cells have been transdifferentiated into insulin-producing cells without expansion, producing cells with an insulin-producing phenotype in small numbers. Furthermore, it has not been previously possible to obtain insulin-producing cells in good numbers using acinar cells as starting material.  
         [0008]     Thus, there is a need for a simple cell culture system and method for rapidly generating large numbers of cells that can further differentiate into, e.g., insulin-producing cells, through expansion and differentiation of the abundant pancreatic acinar cells. Further, there is a need for a cell culture system and method for culturing and transforming such cells into insulin-producing cells. One cell culture system and related method disclosed herein allows a simple, one-step approach that generates expanded cultures that contain at least 80% intermediate progenitor cells that can give rise to insulin-producing cells. A second cell culture system and related method allows the further culturing of these intermediate progenitor cells or other glandular epithelial cells to obtain insulin-producing cells. Both IP cells and insulin-producing cells will be useful for cell-based therapies for the treatment of diseases such as diabetes.  
       SUMMARY OF THE INVENTION  
       [0009]     The present invention provides compositions and methods whereby, e.g., acinar cells can be cultivated successfully in vitro, undergoing a 3-4 fold increase in cell number over time, and giving rise to a cell population that co-expresses acinar and ductal markers early during the culture (2-3 days ex vivo), then ultimately (e.g., about 7-8 days ex vivo) acquires a modified phenotype characterized by expression of some acinar-associated genes, as well as some liver-associated genes. The genes expressed by these modified cells at about 7-8 days ex vivo include, e.g., ductular cytokeratins (CK7, CK8, CK18 and CK19), hepatic nuclear factor 1 (HNF1), alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific (basic helix-loop-helix (bHLH) transcription factor, Thy-1, CCAAT/enhancer-binding protein (C/EBP)-alpha and C/EBP-beta. These cells exhibit little if any expression of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase. By “little if any” expression of a gene is meant herein that gene expression is generally undetectable under conventional methods, such as the hybridization and immunocytochemical methods described herein, but expression may be detected by extraordinarily sensitive methods, such as PCR-based analysis. This type of modified cell is referred to herein as an intermediate progenitor (“IP”) cell. The expanded/transdifferentiated acinar cells (IP cells) can be produced using a general serum-containing media, or, in a preferred method, can be produced without serum on a surface comprising one or more extracellular matrix molecules (ECMs) in the presence of one or more soluble active factors. ECMs can be presented in 2 dimensional or 3 dimensional culture systems in the presence of soluble active factors.  
         [0010]     The IP cells generated from these cultures are expected to be useful directly in certain medical applications. For example, there is evidence that such cells may under certain conditions become functioning insulin-producing cells when implanted in diabetic patients. The cells can also be used for drug discovery and toxicity studies.  
         [0011]     In addition, according to a further aspect of the invention, the IP cells can be cultivated further, in a serum-free medium composed of any standard serum-free base medium (DMEM:HamsF12, for example) with BSA and combinations of factors, including ECMs, small molecules, and growth factors. After 5-10 days of culture, the IP cells undergo additional steps of differentiation, culminating in the formation of cell aggregates that express pro-insulin and C-peptide. Challenge of these cultures with a high-glucose medium causes release of insulin and C-peptide into the medium, indicating the production in these cultures of functional islet-like cells.  
         [0012]     Thus, in a first aspect, the present invention provides a cell culture system comprising a superior cell attachment surface that also stimulates cellular expansion, and a simple culture medium including effective amounts of one or more soluble active factors, or serum (e.g. fetal bovine serum), added to a base medium composition. The cell culture system will be particularly useful for primary culture of mammalian epithelial cells, particularly human epithelial cells. In a preferred embodiment the cell culture system is used for the expansion and transdifferentiation of primary acinar cells, especially human pancreatic acinar cells.  
         [0013]     The cell attachment surface for this cell culture system is any surface to which the cells can attach and expand, including both 2 dimensional (e.g. plates, flasks, roller bottles, petri dishes, wells etc.) and 3 dimensional (e.g. scaffold) environments. Preferably the surface comprises at least one type of ECM, or a peptide fragment thereof. Cells may, in some circumstances, detach from these surfaces and form self-supporting aggregates. Suitable fragments include peptides consisting of a sequence of three of more amino acid residues that are identical to any portion of the amino acid sequence of the ECM. Such fragments can be easily made and tested by means known to those of skill in the art. Most preferably the surface is a layer of collagen I. Many other surfaces known in the art are also suitable, such as Collagen VI, Collagen IV, Vitronectin, or Fibronectin. Collagen I is preferred due to ease and cost.  
         [0014]     The base medium to which the soluble active factors are added may be any cell culture medium appropriate for growth and differentiation of epithelial cells. These include, but are not limited to, DMEM, Hams F12, MEM, M-199 and RPMI. The general requirements for such culture media and many suitable examples are known to those of skill in the art. To this base medium is added either serum (such as fetal bovine serum), or a stabilizing protein such as bovine serum albumin (ISA) along with effective amounts of soluble active factors. The medium is preferably serum-free.  
         [0015]     Soluble active factors for the expansion and transdifferentiation of primary pancreatic acinar cells into IP cells include growth factors such as HGF receptor activators and EGF receptor activators. Preferred soluble active factors include one or more of EGF and Transforming Growth Factor-α, IGF1, HGF, betacellulin, prolactin and gastrin 1. HGF, EGF and/or Transforming Growth Factor-α are particularly preferred. Also preferred is the combination of IGF1 and betacellulin.  
         [0016]     In one particularly preferred embodiment, the base medium contains a 1:1 mixture of DMEM and Hams F12. The base medium is completed with the addition of glutamine to a final concentration of ˜4 mM, insulin (˜0.1-10 μg/ml, preferably ˜0.01 mg/ml), transferrin (˜0.5-10 μg/ml, preferably ˜0.0055 mg/ml), selenium (˜0.25-5.0 ng/ml, preferably ˜0.0067 μg/ml of sodium selenite), and Epidermal Growth Factor (EGF) (˜1-20 ng/ml, preferably ˜10 ng/ml); this medium is hereafter referred to as pancreatic cell medium, or PCM. To this base medium formulation, up to ˜20% Fetal Bovine Serum (or other serum), preferably between ˜10-˜15% fetal bovine serum, most preferably about 10% or up to about 15% fetal bovine serum) may be added, or, to create a serum-free culture environment, the following components are added in place of serum: heat-inactivated bovine serum albumin (0.1-2%), Hepatocyte growth factor (HGF) (1-20 ng/ml), and/or Transforming Growth Factor Alpha (TGFα)(1-10 ng/ml). In addition, the medium may contain Betacellulin (0.5-20 ng/ml), Gastrin 1 (0.05-10 ng/ml), Prolactin (1.0-10 ng/ml), and/or IGF-1 (5-100 ng/ml). In particular formulations, greater or lesser amounts of these components may be added in order to achieve a formulation that is effective in supporting the expansion and transdifferentiation of the cells. Persons of skill in the art will appreciate that determining effective amounts of the components will require no more than routine experimentation.  
         [0017]     By the use of this attachment surface and medium, the expansion and transdifferentiation of primary pancreatic cells with the desired phenotype is simplified greatly.  
         [0018]     In a particularly preferred embodiment, the cell culture system is a combination of collagen I coated tissue culture surface (presented in a 2 dimensional or 3 dimensional form) and a serum-free medium containing BSA, insulin, transferrin, selenium, Hepatocyte growth factor (HGF), Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGFA).  
         [0019]     The cell culture system enables superior attachment in vitro of primary pancreatic epithelial cells for adherent culture compared to prior methods, while creating a cellular environment that promotes expansion of the epithelial component of primary pancreatic cultures with concomitant transdifferentiation of the acinar cells present in the starting material into IP cells, while minimizing emergence of undesired fibroblasts. Advantages of this culture system are ease of construction, few components needed, and that all components are readily available and easily used in the required manner.  
         [0020]     The components of this aspect of the invention may be conveniently packaged in the form of a kit. The kit may include, for example, 1) a cell culture medium such as DMEM: 2) a serum-free medium supplement containing BSA, insulin, transferrin, selenium, HGF, EGF and TGFA, in suitable amounts to yield the concentrations noted above in the completed medium; and 3) at least one collagen I coated substrate, such as a vessel for tissue culture (e.g., dish(es) with at least one collagen-1 coated tissue culture surface), or collagen-1 coated inserts for use in culture dishes or other laboratory ware. The kit may also optionally include a tissue culture dish or other cell culture accessories and additional reagents that may be required to carry out epithelial cell culture and differentiation.  
         [0021]     Culture systems consisting of scaffolds, collagen coated flasks or other vessels and serum-free base medium may be packaged along with the soluble active factors as a separate vial that would be added to the culture medium just prior to use. The active factor combination can be added to a variety of base media to accomplish the same end, e.g., growth and differentiation of primary pancreatic acinar cells in vitro. Such culture systems should also be useful for other cell types, particularly glandular epithelial cells derived from other organs and tissues, including those from liver, pancreas, intestine, prostate, and breast.  
         [0022]     The collagen I surface provides superior cell attachment (thereby increasing the number of cells that adhere during initial culture and thus enhancing culture efficiency), while the collagen I and the combination of soluble active factors (e.g., HGF, TGFA and EGF) promote continued proliferation of cells over time, leading to an increase in cell number above what has been previously reported for primary pancreatic acinar cells. Furthermore, the expansion of the acinar cells is accompanied by a transdifferentiation in the majority of cells to an IP phenotype, which is potentially a therapeutically useful cell phenotype for the treatment of diseases such as diabetes. This likely occurs due to convergence of the intracellular signaling pathways associated with collagen I, HGF, TGFA and EGF, creating a synergistic response.  
         [0023]     The cell culture system of the present invention has unexpected advantages over systems previously in use. Collagen I, IV, VI, Vitronectin and Fibronectin were expected to enhance cell attachment. However, other extracellular matrix molecules that yielded equivalent attachment of cells during the initial 18 hours of culture did not promote consistent growth of the cells over time in the serum-free medium containing HGF/EGF/TGFA. The most efficient and cost-effective method of achieving cell expansion AND differentiation into IP cells is to utilize a collagen-I surface and a medium containing reduced serum (preferably less than 20%, more preferably less than 15%, 10%, or 5%, most preferably 2%).  
         [0024]     Another aspect of the invention is a method for culturing mammalian epithelial cells comprising adding said cells to the cell culture system described above, and maintaining them at suitable temperature and atmospheric conditions. By “mammalian epithelial cell” is meant any cell of a tissue or organ with an epithelial cell phenotype, defined by the presence of expression of cytokeratins and often through the presence of markers that suggest a tissue-specific function (i.e., epithelial cells of the skin make keratin, epithelial cells of the intestine make mucin, epithelial cells of the prostate make PSA). In a preferred embodiment, the cells are primary pancreatic cells, particularly human pancreatic cells. Suitable temperature for mammalian cells is usually in the range of about 37° C., but may be varied somewhat according to cell type. The atmosphere can be ordinary air, or other specialized mixtures of gasses suitable for maintaining cells, as will be familiar to persons of skill in the art. Expansion of pancreatic acinar cells can be maximized by decreasing the oxygen tension in the culture atmosphere to less than 21%, while transdifferentiation to IP cells can be enhanced by increasing oxygen tension to greater than 5%. A preferred range of oxygen tension is between about 5% and about 21%.  
         [0025]     In a second aspect, the invention also provides methods and compositions for transforming glandular epithelial cells that have acquired expression of markers characteristic of an intermediate progenitor (IP) phenotype as described above into insulin-producing cells. By “glandular epithelial cell” is meant an epithelial cell that is a component of a gland. Glands are tissues that have a specific function related to secretion of key molecules—most organs in the body have glandular function (liver, intestine, pancreas, prostate, breast, pituitary, adrenal, kidney) whereby they produce and release hormones, digestive enzymes, or other life-essential fluids. Glandular epithelial cells from endoderm-derived organs (e.g., liver, intestine, pancreas) share many characteristics, including the ability to express many of the same genes. Particularly preferred are glandular epithelial cells from pancreas, for example acinar cells. As used herein, the terms “express” and “expression” generally refer to nucleic acids (e.g., mRNAs) or to protein gene products that are detectable by standard immunocytochemical methods.  
         [0026]     In this aspect, the invention provides a second cell culture system comprising a cell attachment surface and a culture medium that supports and promotes the transformation of glandular epithelial cells into insulin-producing cells. The cell attachment surface is similar to and may be identical to the attachment surface for expanding primary pancreatic acinar cells. It may be presented in the form of a flat surface coated on a vessel or in the form of a scaffold or other surface adapted for cell culture. It can be comprised of, or coated with, any composition that is capable of maintaining cells or supporting cell growth. In a preferred embodiment, it comprises at least one ECM, such as Collagen I, Collagen VI, Collagen IV, Vitronectin or Fibronectin. In a particularly preferred embodiment, the cell attachment surface is Collagen-I.  
         [0027]     In this aspect, the invention provides a further culture medium comprising at least one differentiation promoting factor (“DPF”) that promotes the transformation of glandular epithelial cells into insulin producing cells. The DPFs for the transformation of glandular epithelial cells into insulin producing cells can be one or more of Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), or VEGF. Preferred concentrations in culture medium of each of these 23 DPFs are listed in Table 1. Although in some cases one DPF is sufficient, preferably two or more factors are used. As many as all 23 of the factors may be used.  
                             TABLE 1                           Concentration       Substance   (micrograms/mL)                                Activin A (human, recombinant)   0.0005       CGRP alpha, (Calcitonin Gene Related Peptide, rat)   0.1905       C natriuretic peptide) (human, porcine, rat: frag 32-53)   0.10985       (CNP)       Cholera Toxin B Subunit, recombinant   0.0125       DEXamethasone (9 alpha-fluoro-16alpha-   0.002       methylprednisolone)(hydrocortisone analogue)       FGF acidic (aFGF = FGF1), Recombinant Human   0.0025       GLP-1 (7-36) amide, human (Glucagon-Like Peptide   0.033       1)       Glucose (base should be I0ow; 0.9 ug/ml)   1.08       Insulin, human (low [ ] in base media 1 ug/ml)   9.5       LIF, human (leukemia inhibitory factor, human)   0.0025       PDGF AA + PDGF BB MIX   0.005       TGF alpha   0.001       Prolactin (human, recombinant)(a plasma growth   0.0012       hormone)       Trolox (soluable Vitamin E) (C14H18O4)   0.625       GRP (Gastrin Releasing Peptide, Human)   0.143       IGF-1, recombinant human   0.0025       IGF-2, recombinant human   0.0025       Laminin   2.25       Met-Enkephalin (tyr-gly-glyl-phe-met)   0.003       Sonic Hedgehog (mouse, recombinant)   0.025       Substance P (full length) (H1875 is frag 1-4)   5       FGFb (=FGF2), human Recombinant   0.0025       VEGF   0.0025                  
 
         [0028]     In a preferred embodiment of this aspect of the invention, the culture medium comprises at least one (or as many as all 10) of the following differentiation promoting DPFs:.C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Laminin, Met-Enkephalin, PDGFAA+PDGFBB, Sonic Hedgehog, and Substance P.  
         [0029]     In a preferred embodiment, the culture medium that promotes the transformation of glandular epithelial cells into insulin producing cells consists of a 1:1 mixture of DMEM and Hams F12 plus the components listed in Table 2. This medium is sometimes referred to herein as “Media or Medium G9.” 
                                                 TABLE 2                                           Concentration           Factor   Substance   (Final) ug/ml                                    1   ANP   Atrial Natriuretic   0.1530               Peptide, Rat (28 amino               acids)       2   CCK-8-frag-amide   CCK8, Fragment 26-33   0.0250               Amide               (Cholecystokinin)               (Asp-Tyr(SO3H)-Met-               Gly-Trp-Met-Asp-Phe-               NH2)       3   Caerulin sulfate   Caerulein (Pyr-Gln-   0.0300               Asp-Tyr(SO3H)-Thr-               Gly-Trp-Met-Asp-Phe-               NH2       4   Cholera Toxin-B   Cholera Toxin B   0.0125               Subunit, recombinant       5   Dex   DEXamethasone (9   0.0020               alpha-fluoro-16alpha-               methylprednisolone)               (hydrocortisone               analogue)       6   FGF-7   FGF7 (KGF)   0.0025       7   GLP-1   GLP-1 (7-36) amide,   0.0330               human (Glucagon-Like               Peptide 1)       8   GRP   GRP (Gastrin   0.1430               Releasing Peptide,               Human)       9   Gastrin-1   Gastrin I Human   0.0000       10   Glucose   Glucose (base should   1.0800               be I0ow; 0.9 ug/ml)       11   HGF   Hepatocyte Growth   0.0025               Factor (HGF)               recombinant       12   IGF-1   IGF-1, recombinant   0.0025               human       13   IGF-2   IGF-2, recombinant   0.0025               human       14   Insulin   Insulin (low [ ] in base   9.5000               media 1 ug/ml)       15   Leu-Enkephalin   Leu-Enkepthalin (tyr-   0.0030               gly-gly-phe-leu)       16   Nicotinamide   Nicotinamide   610.0000       17   PTHRP-frag-1-34   pT II RP (Parathyroid   0.2060               Hormone Related               Peptide (1-34), human)       18   Progesterone   Progesterone   0.0030       19   Prolactin   Prolactin (human,   0.0012               recombinant)(a plasma               growth hormone)       20   Retinol acetate   Retinoic Acid (Vitamin   0.0250               A)       21   SHH   Sonic Hedgehog   0.0250               (mouse, recombinant)       22   Sodium selenite   Selenium (Selenous   0.0250               Acid, Na salt)       23   Soybean trypsin inhibitor   Trypsin Inhibitor,   0.5000               soybean (type I-S)       24   TGF-beta sRII   TGF beta sRII (soluable   0.0050               receptor type 2)       25   Transferrin   transferrin   2.7500       26   Trolox   Trolox (soluable   0.6250               Vitamin E) (C14H18O4)       27   VIP   Vasoactive Intestinal   0.0665               Peptide (VIP), human       28   aFGF   FGF acidic   0.0025               (aFGF = FGF1),               Recombinant               Human       29   bFGF   FGFb (=FGF2), human   0.0025               Recombinant       30   n-Butyric acid   n Butyric Acid, Sodium   4.5400               Salt                  
 
         [0030]     The components of this aspect of the invention may also be conveniently packaged in the form of a kit. The kit may include, for example, 1) a cell culture medium such as DMEM, Hams F12, or a combination thereof; 2) a serum-free medium supplement containing: BSA and the DPFs Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), or VEGF, or two or more of these components in combination, in suitable amounts to yield the concentrations noted in Table 1 in the completed medium; and 3) tissue culture dish(es) with at least one collagen-1 coated tissue culture surface (or collagen-1 coated inserts for use in culture dishes or other laboratory ware). The kit may also optionally include a tissue culture dish and/or other cell culture accessories and additional reagents that may be required to carry out epithelial cell culture and differentiation. In other embodiments, the kit may contain any of the media or media components discussed herein.  
         [0031]     Culture systems consisting of scaffolds, collagen coated flasks or other vessels and serum-free base medium may be packaged along with the DPF(s) as a separate vial that would be added to the culture medium just prior to use. The DPF combination can be added to a variety of base media to accomplish the same end, e.g., growth and differentiation of primary pancreatic acinar cells in vitro. Such culture systems may also be useful for other cell types, particularly other epithelial cells derived from glandular tissues, including those from liver, pancreas, intestine, prostate, and breast.  
         [0032]     The invention also provides a method for converting glandular epithelial cells into insulin-producing cells comprising culturing the glandular epithelial cells in the cell culture system described above. The method may further comprise removing the culture medium from the cell culture, re-feeding the cell culture with a serum-free medium with glucose, and measuring proinsulin production C-peptide production, or insulin release.  
         [0033]     Furthermore, the invention provides an isolated population of insulin-producing cells containing cytoplasmic granules with immunodetectable proinsulin, insulin, and/or c-peptide that is derived from a population of cells of which a subset of cells expressed at least one marker associated with IP cells (e.g., expressed some acinar-associated genes, as well as some liver-associated genes, including, e.g., ductular cytokeratins (CK7, CK8, CK18 and CK19), HNF1, alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific bHLH transcription factor, Thy-1, C/EBP-alpha and C/EBP-beta, and expressed little if any of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase).  
         [0034]     By an “isolated” cell or population of cells is meant herein that the cell or cell population is removed from its original environment (e.g., the natural environment if it is naturally occurring), and isolated or separated from at least one other component with which it is naturally associated. For example, a naturally-occurring cell present in its natural living host is not isolated, but the same cell, separated from some or all of the coexisting materials in the natural system, is isolated. Such cell or cell populations could be part of a cell culture or cell population, and still be isolated in that such culture or population is not part of its natural environment.  
         [0035]     In one preferred embodiment, the insulin-producing cells are derived from glandular epithelial cells obtained from mammalian pancreas, such as primary acinar cells.  
         [0036]     The data disclosed in the examples below are generated from freshly isolated human pancreatic cells. The expansion of primary human pancreatic cells in these conditions produces cultures with a mixed epithelial IP phenotype, suitable for in vitro studies of IP cells for a variety of purposes, and suitable for transplantation in vivo for cell therapy for the treatment of diseases such as diabetes. The IP cells generated by these methods may also be useful in the study of pancreatic cell biology, as normal controls in the study of pancreatic epithelial cancers, and to test the effects of drugs/compounds on normal pancreatic epithelial cells (ductal or acinar). Furthermore, the cells may be further cultured to yield insulin-producing cells as demonstrated below. 
     
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       [0037]     FIGS.  1 A-D show microscopic images after treatment of starting material with antibodies to amylase ( FIG. 1A ), insulin ( FIG. 1B ), and CK19 ( FIG. 1C ) and the composition of the cell pellet of freshly isolated primary human pancreatic cells ( FIG. 1D ).  
         [0038]      FIG. 2  shows growth curves constructed from primary human pancreatic cultures grown in commercial medium (with serum) or in the described pancreatic cell medium (PCM) with serum.  
         [0039]      FIG. 3  shows a comparison of cell expansion in the base medium composition described vs. base medium+soluble growth factors (serum-free formula) vs. base medium+fetal bovine serum.  
         [0040]     FIGS.  4 A-B shows the effect of different culture surfaces on total cell number ( FIG. 4A ) and cell phenotype ( FIG. 4B ) after expansion.  
         [0041]     FIGS.  5 A-B show a comparison of cell phenotype after expansion in serum-containing ( 5 A) and serum-free ( 5 B) medium containing all soluble active factors.  
         [0042]      FIG. 6  shows high power images of cell cultures expanded in various conditions, including serum-free base media supplemented with 3 soluble active factors, HGF, EGF &amp; TGFA. Note epithelial morphology.  
         [0043]      FIG. 7  shows a demonstration of growth of IP cells on ECM-coated surfaces as determined by metabolic activity assay over time. Note superior growth when Collagen I surface is combined with the media formulation described herein, yielding results superior to the combination of Matrigel and commercial media with serum.  
         [0044]      FIG. 8A  (upper left) shows expression of amylase by acinar cells after two days of culture (red staining),  FIG. 8B  (lower left) shows expression of CK19 (green staining),  FIG. 8C  (right) shows an overlay of the two images, showing co-expression (yellow) in a large proportion of cells.  
         [0045]      FIG. 9  shows changing phenotype of primary acinar cells in culture over 5 days. Amylase is red, CK19 is green. Note appearance of yellow (amylase+CK19) on Day 2 and 3.  
         [0046]      FIGS. 10A and 10B  show primary human pancreatic cells that were expanded in serum-containing medium on Collagen I coated surface. Images were analyzed to determine total cells ( FIG. 10A , blue nuclei) and total positive cells ( FIG. 10B , blue nuclei surrounded by green staining for CK19).  
         [0047]      FIG. 11  shows light microscopic (200×) appearance of pancreatic acinar cells cultured on a collagen I surface with all DPFs (Activin A, 0.5 ng/ml; acidic FGF, 2.5 ng/ml; basic FGF, C-Natriuretic Peptide (CNP), 0.11 μg/ml; Calcitonin Gene Related Peptide, 0.19 μg/ml; Cholera Toxin B Subunit, 12.5 ng/ml; Dexamethasone, 0.002 μg/ml; Gastrin-Releasing Peptide, 0.143 μg/ml; Glucagon-like Peptide-1 (GLP-1), 0.033 μg/ml; Glucose, 1.08 μg/ml; IGF1, 0.0025 μg/ml; IGF2, 0.0025 μg/ml; Insulin, 9.5 μg/ml; Laminin, 2.25 μg/ml; LIF, 0.0025 μg/ml; Met-Enkephalin, 0.0030 μg/ml; PDGFAA+PDGFBB (0.0050 μg/ml: 0.0025 μg/ml of PDGFAA+0.0025 μg/ml PDGFBB); Prolactin, 0.0012 μg/ml; Sonic Hedgehog, 0.025 μg/ml; Substance P, 5.0 μg/ml; TGF-alpha, 0.0010 μg/ml; Trolox (alpha-tocopherol derivative), 0.625 μg/ml; and VEGF, 0.0025 μg/ml).  
         [0048]      FIG. 12A  (top right panel) shows immunocytochemical analysis with CK19 antibodies (green).  
         [0049]      FIG. 12B  (lower right panel) shows immunocytochemical analysis with C-peptide antibodies (red).  
         [0050]      FIG. 12C  (left panel) shows an overlay image demonstrating the colocalization of CK19 and C-peptide (orange). Blue portions are DAPI stained nuclei.  
         [0051]      FIG. 13A  shows insulin release upon glucose challenge in IP cells that have not been detached and relocated (subcultured) during the growth and differentiation process.  
         [0052]      FIG. 13B  shows insulin release upon glucose challenge in IP cells that have been subcultured according to Example 10.  
         [0053]      FIG. 13C  shows C-peptide release upon glucose challenge in IP cells that have not been subcultured according to Example 10.  
         [0054]      FIG. 14  shows the Isulin/DNA ratio in subcultured and nonsubcultured cells that are treated with Combinations 1, 2 and 3 of DFP media, as described in Example 11.  
         [0055]      FIG. 15  shows insulin release in response to base level glucose (5 mm) and a glucose challenge (22 mm) over 10 days of culture in PCM and DPF media, as described in Example 13.  
         [0056]      FIG. 15A  shows insulin release in response to base level glucose (5 mm) and a glucose challenge (22 mm) over 14 days of culture in PCM and DMG9 media, as detailed in Example 14.  
         [0057]      FIG. 16  is a graphical representation of the characteristics of the 17 classes of genes shown in Table 6, as indicated in the last column of the Table, as detailed in Example 14. 
     
    
     DETAILED DESCRIPTION OF THE INVENTION  
       [0058]     In describing preferred embodiments of the present invention, specific terminology is employed for the sake of clarity. However, the invention is not intended to be limited to the specific terminology so selected. It is to be understood that each specific element includes all technical equivalents, which operate in a similar manner to accomplish a similar purpose. Each reference cited here is incorporated by reference as if each were individually incorporated by reference.  
         [0059]     The following abbreviations are used: 
    BSA: bovine serum albumin     BMP Bone Morphogenetic Protein     bHLH: basic helix loop helix     DMEM: Dulbecco&#39;s Modified Eagle&#39;s Medium     TGF β1: Transforming Growth Factor β1     ECM: extracellular matrix molecules; naturally occurring proteins produced by cells of a tissue that provide structural support as well as a source of cellular signals related to adhesion. Examples are collagen, vitronectin, fibronectin, laminin.     EGF: Epidermal Growth Factor     Hams F12: Ham&#39;s Nutrient Mixture F12     HGF: Hepatocyte growth factor     HNF-1: Hepatic nuclear factor 1     IGF1: Insulin-like growth factor 1     IGF-II: Insulin-like growth factor 2     IP cells: Intermediate progenitor cells derived from an epithelial cell, such as, e.g., a pancreatic acinar cell or a liver cell, wherein the derived cells express some acinar-associated genes, as well as some liver-associated genes, including, e.g., cytokeratins (CK7, CK8, CK18 and CK19), HNF1, alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific bHLH transcription factor, Thy-1, C/EBP-alpha and C/EBP-beta, and express little if any of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase).     PDGF-A: Platelet derived growth factor alpha     PDGF-B: Platelet derived growth factor beta     TGFA, TGF-α: Transforming Growth Factor α   
 
         [0076]     As used herein, the term “culture system” is intended to mean a system for growing and/or differentiating cells in culture, which comprises a cell attachment surface, preferably one that also stimulates cellular expansion, and a culture medium, which includes effective amounts of one or more factors, or serum (e.g. fetal bovine serum), added to a base medium composition.  
         [0077]     When referring to active soluble factors and DPFs herein, “effective amount” means an amount that either alone or in combination with other included factors is effective in promoting either expansion and differentiation into IP cells, or into insulin-producing cells, as applicable.  
       EXAMPLES  
       [0000]     I. Expansion and Transdifferentiation of Primary Acinar Cells into Glandular Epithelial Cells (Culture Phase I)  
         [0000]     Materials and Methods:  
         [0078]     Starting Material: Primary human pancreatic acinar cells are collected as waste from standard COBE gradient preparation of islet cells for transplantation (Lake et al., 1989). After density gradient centrifugation, the islets are present as a layer between 1.063 density and 1.10 density, and the remaining cells are collected as the pellet that sediments to the bottom of the gradient based on density. Approximately 48 hours after collection of the cells at the transplant center are received by the inventors in non-tissue-culture treated polystyrene flasks and are suspended in RPMI+10% fetal calf serum at a density of approximately 2.0 million cells/ml. Cell number and viability is assessed by trypan blue exclusion and enumeration on a hemacytometer by light microscopic observation.  
         [0079]     Phenotypic Evaluation of Starting Material. A preparation of starting material was formalin fixed and paraffin-embedded as a cell pellet about 24 hours after initial harvest of the pancreatic cells. Paraffin sections were prepared, placed on slides, and subjected to immunocytochemical analysis with antibodies to insulin (Biogenex, San Ramon, Calif.), CK19 (Biogenex), and Amylase (Biogenex). A minimum of (3) sections per sample were assessed with each marker. All antibody staining was carried out according to the manufacturer&#39;s suggestion with pre-diluted commercial antibodies. For CK19, a 3 minute treatment with pepsin enzyme (Biogenex) preceded the blocking step for the purpose of antigen retrieval. Briefly, the sections were rehydrated through graded ethanols, followed by a 15 minute incubation in phosphate buffered saline (PBS) without calcium and magnesium. Protein Blocker (Biogenex) was added for 30 minutes prior to addition of primary antibodies. After (3) 5-minute washes, biotinylated secondary antibody (Biogenex) was added at a 1:100 dilution and sections were incubated for 30 minutes at room temperature. After (3) 5-minute washes, Alexa488 or Alexa-596-conjugated StreptAvidin (Molecular Probes, Eugene, Oreg.) was added for fluorescent visualization. For each slide, a minimum of (3) 200× images were captured using a Nikon fluorescent microscope fitted with a SPOT camera (Diagnostic Systems, Inc., Webster, Tex.). The images were assessed quantitatively using image analysis software (MetaMorph/Universal Imaging Corporation, Downington, Pa.) to determine relative fraction of insulin-positive, CK19+, and amylase+ cells. Insulin+ cells are the beta cells of the islets, CK19+ cells are the primary ductal cells, and amylase+ cells are the acinar cells (see Example 1).  
       Example 1  
     Characterization of Cell Culture Conditions  
       [0000]     A. Serum-Free Medium  
         [0080]     Freshly isolated primary human pancreatic cells were collected as a pellet from a COBE cell separator, fixed in formalin, paraffin-embedded, sectioned, and analyzed with antibodies to amylase, CK19, and Insulin. Images ( FIGS. 1A and 1B ) were collected on a Universal Imaging System (Universal Imaging Corporation) and analyzed with MetaMorph Software. This cell pellet ( FIG. 1C ) was comprised of 1.0% insulin+ cells (beta cells of the islet), 5.8% CK19+ cells (primary ductal cells), and 93.2% amylase+ and unlabeled (acinar cells and other cell types).  
         [0081]     Primary human pancreatic cells were then seeded at 10 4  or 10 5  cells/cm 2  onto tissue culture treated polystyrene in either DMEM commercial medium plus 10% fetal bovine serum or in PCM plus 10% fetal bovine serum. Replicate cultures were harvested at 3 day intervals via trypsinization and live cells (as determined by trypan blue exclusion) and enumerated on a hemocytometer. The results (shown in  FIG. 2 ) demonstrate that the (serum-containing) medium formulation described herein is superior to commercial media formulation for growth and maintenance of primary pancreatic cells.  FIG. 3  compares the results of expanding the cells for 6 days in base medium, base medium plus all of the soluble active factors [HGF, ˜1-˜20 ng/ml, preferably ˜5.0 ng/ml; TGFA, ˜1-˜10 ng/ ml, preferably ˜2 ng/ml; Betacellulin, ˜0.5-˜20 ng/ml, preferably ˜10 ng/ml; Gastrin 1, ˜0.05-˜10 ng/ml, preferably ˜0.06 ng/ml; Prolactin, ˜1.0-˜10 ng/ml, preferably ˜2.4 ng/ml; and IGF1, ˜5-˜100 ng/ml, preferably ˜5 ng/ml)] and base medium plus 10% serum. The serum-free media formulation meets/exceeds expansion provided by media+serum.  
         [0082]     The cell expansion experiment was repeated essentially as above, except that the base medium was supplemented with only three of the soluble active factors: TGF, HGF, and EGF.  FIG. 6D  compares the results of expanding the cells in the various media;  FIGS. 6A, 6B  and  6 C show high power images of the cell cultures expanded under the various media conditions.  
         [0000]     B. ECM Surfaces  
         [0083]     The attachment of primary human pancreatic cells was evaluated by counting the number of attached cells vs. the number of cells initially seeded on a panel of ECM surfaces comprised of Collagen I (1 μg/cm 2 ), Fibronectin (3 μg/cm 2 ), Laminin (2 μg/cm 2 ), Vitronectin (1 μg/cm 2 ), Matrigel (1 μg/cm 2 ), Human ECM (1 μg/cm 2 ), or Poly-D -Lysine (3 μg/cm 2 ). In one condition, a mixture of Collagen IV, Laminin, and Fibronectin was utilized. ECMs were placed into solution at the above concentrations and allowed to coat tissue culture-treated polystyrene surfaces according to manufacturer&#39;s suggestions of 1 hour at room temp. Excess ECM solution was then removed and surfaces were rinsed twice in water. Just before seeding cells, the water was aspirated, then cells were seeded onto the ECM surface at a density of 1×10 5  cells/cm 2  in growth medium (PCM) composed of DMEM:HamsF12 mixture (1:1) with 4 mM glutamine, 1×ITS supplement (GIBCO 51500-056), 10% Fetal Calf Serum (Inactivated, Qualified, GIBC 26140-079), and 10 ng/ml Epidermal Growth Factor (EGF) (BD 4001). Cells were seeded onto tissue-culture polystyrene surface as a control. After 18 hours, unattached cells were washed away and remaining attached cells were re-fed with PCM and allowed to grow for 7 days prior to evaluation. Cultures were fixed in 10% formalin and subjected to immunocytochemistry with antibodies for CK19 and Amylase as described previously to determine phenotypic composition. Cells were counterstained with DAPI fluorescent blue nuclear stain to visualize individual cell nuclei for cell counting. The metabolic activity of cells subjected to the various conditions was determined by an MTS assay. Viable cells were measured using the MTS assay (Promega CellTiter 96 Aqueous One Solution Cell Proliferation Assay), a colorimetric method for determining the number of viable cells in proliferation or cytotoxicity. The results of this analysis are shown in  FIG. 7 .  
       Example 2  
     Further Studies with ECM Surfaces and Various Media Components  
       [0084]     Primary pancreatic cells, composed of &gt;90% non-islet/non-duct cells, were plated onto various coated surfaces at a density of 28,900 cells/well (10 5  cells/cm 2 ). Unattached cells were washed off after 18 hours, and cultures were re-fed and allowed to grow for 8 days. Cultures were fixed in formalin (10%) and subjected to phenotypic analysis with antibodies to CK19 and Amylase. The results are shown in  FIG. 4A -B. While Collagens I, IV, Laminin, Fibronectin, and Matrigel provide a suitable surface for cell attachment and expansion, maintenance of acinar (amylase+) phenotype along with the presence of an increased proportion of cells with a glandular epithelial phenotype (CK19+) was superior on Collagen I. More than 50% of cells analyzed expressed amylase and more than 50% of cells analyzed expressed CK19, suggesting that a subpopulation of cells in these experimental conditions express both markers.  
         [0085]     Tissue culture-treated polystyrene culture surfaces were coated with Collagen I as described above. Tissue culture medium (PCM) was prepared as described above. In some cases, serum was replaced with Fraction V BSA (99% pure, heat inactivated, Sigma), along with combinations of soluble growth factors, including IGF1, IGF2, betacellulin, HGF, EGF, and TGF-alpha. Optimal seeding density is between 10 4  and 10 5  cells/cm 2 , as demonstrated in Example 3. Cells were seeded onto collagen-coated flasks (150 cm 2 ) at 1.5×10 6  cells/flask in PCM. After an ˜18 hr attachment period, unattached cells were washed away with gentle aspiration/rinse, followed by re-feeding with fresh medium. Cultures were monitored over time by metabolic assay (MT) and by trypsinization and cell counting, to establish cell number (see example 3). Cell phenotype at the end of the culture period was assessed as follows: small-scale cultures were set up simultaneously in 96-well plates. At the end of the culture phase, monolayer cells were fixed in 10% formalin for a minimum of 1 hour. After formalin was removed and monolayers were rinsed, cultures were subjected to immunocytochemistry as described in previous section for CK19, amylase, insulin, and vimentin (a marker of fibroblasts). The relative fraction of CK19+ cells was determined by quantitative image analysis as described above (see Example 4). After formalin was removed and monolayers were rinsed, cultures were subjected to immunocytochemistry as described in previous section for CK19 and vimentin (a marker of fibroblasts). Cells were also stained with amylase antibodies, but did not produce positive results due to release of digestive enzymes, such as amylase, by the cells over time in culture. The relative fraction of CK19+ cells was determined by quantitative image analysis as described above (see example 4). Acquisition of ductal markers by acinar cells was verified by demonstrating concomitant expression of CK19 and amylase in cell subpopulations during days 2-3 of culture (see example 5). For these experiments, CK19 primary antibodies were reacted with formalin-fixed cell cultures, followed by visualization with Alexa488-conjugated Goat anti-mouse IgG (Molecular Probes). Then, cells were subjected to a blocking step (Protein Blocker, BioGenex), followed by application of the second primary antibody (anti-amylase). Visualization of the amylase was accomplished by application of Alexa594-conjugated Goat Anti-Mouse IgG. Images were collected as described above. At the end of a 7-day culture period in the conditions described herein, between 65-90% of the cells in the culture express CK19, while less than 20% express vimentin (see example 6). Variations in the relative proportion of CK19+ cells probably reflect heterogeneity due to age, gender, and other unique characteristics of individual patients.  
       Example 3  
     Density of Cell Seeding  
       [0086]     Primary pancreatic cells were seeded at (3) densities on tissue-culture treated polystyrene dishes (60 mm) and fed with PCM. Light microcopic observations were made daily. At the 24-hour timepoint, dishes were sacrificed and stained with trypan blue to assess viability. The results are shown in Table 3.  
                           TABLE 3                       Seeding           After 3 days       Density   At 24 Hours:   At 48 Hours:   Growth:                   10 4  cells/cm 2     Most cells attached,   Mitotic Figures present   Epithelial           trypan blue negative   (light microscopy)   monolayer           (live)       forming       10 5  cells/cm 2     Most cells attached,   Mitotic Figures present   Epithelial           trypan blue negative   (light microscopy)   monolayer           (live)       forming       10 6  cells/cm 2     Some cells attached,   Few Mitotic Figures   Cells are           most are trypan blue   present (light   detached;           positive (dead)   microscopy)   some                   fibroblasts                   present                  
 
       Example 4  
       [0087]     Cells were grown on a Collagen I surface, at 37° C. in 21% oxygen, in PCM medium or in base medium with 2% BSA, 2 ng/ml TGF-α, 10 ng/ml EGF, and 10 ng/ml HGF. After 7 days, cultures were fixed in 10% formalin and subjected to immunocytochemical analysis with fluorescent detection, followed by automated image collection and analysis. The results are shown in  FIGS. 5A and 5B . Fibroblast (vimentin+) fraction, glandular epithelial cell fraction (CK19+), and fraction of unlabeled cells (Other) are similar after expansion. This suggests that replacement of serum with the serum-free medium maintains fraction of CK19+ cells without overgrowth of fibroblasts as compared to cells grown in serum-containing media.  
       Example 5  
       [0088]     Primary pancreatic acinar cells were cultured for several days in a 1:1 ratio of DMEM and HamsF12, with 10% fetal bovine serum, 0.01 mg/ml insulin, 0.005 mg/ml transferrin, 0.0067 μg/ml sodium selenite, 10 ng/ml EGF, 4 mmol/liter glutamine and antibiotics. After 2 days of culture (4 days ex vivo), expression of amylase by the acinar cells is still strong ( FIG. 8A , upper left panel, red staining) as determined by immunocytochemistry. Expression of CK19 is also apparent ( FIG. 8B , lower left panel, green staining). Overlay of the two images ( FIG. 8C ) demonstrates clear co-expression of amylase and CK19 in a large proportion of the cells, indicating that an intermediate cell exists from active conversion of amylase+ acinar cells to an amylase+/CK19+ mixed acinar/ductal phenotype (AD cells). Daily evaluation of cultures ( FIG. 9 ) demonstrated that onset of CK19 expression begins around Day 2 of culture and by Day 5 cultures have lost most immunodetectable amylase expression and CK19 expression is prevalent.  
       Example 6  
       [0089]     After 7 days of growth in PCM/Collagen I surface, cells were fixed, stained with antibodies to CK19, and counterstained with nuclear DAPI. Total cell number was evaluated by automated image analysis ( FIG. 10A  left panel, blue-stained cell nuclei), while CK19+ cells were counted ( FIG. 10B , right panel, green-stained cell cytoplasm). Of 378 total cells, 342 were immunopositive for CK19 (90%). After approximately 7 days of culture using conditions described herein, the acinar cells have concrete ductular characteristics, now referred to as IP cells. For most primary human cultures, more than 80% of cells in the culture after about 7 days express markers such as CK19 that are associated with ductular cells from a variety of tissues.  
       Example 7  
     Gene Expression Analysis of 7-Day Cultures (IP Cells)  
       [0090]     Two independent IP cell cultures were subjected to Clontech 8K Atlas Gene Array analysis. IP cells were obtained by culturing primary acinar cells in a cell culture system comprising PCM and a Collagen I surface. Monolayer cultures were rinsed 2× with PBS, then detached from the flasks with 0.25% trypsin. Cells were pelleted by centrifugation at 1,200 RPM for 3 minutes in a swinging bucket centrifuge. Cell pellets were resuspended and washed 2× in PBS before a final centrifugation at 1,200 RPM for 3 minutes as described above. The supernatant was discarded and gently aspirated to remove as much liquid as possible from the cell pellet, which was then quick-frozen in a dry-ice/ethanol bath and stored at −80° C. until transfer to BD Clontech where gene expression analysis was performed, using conventional techniques.  
         [0091]     Labelled P-33 cDNA probes were prepared from the 30 μg of total RNA from each sample by first enriching for poly A+RNA using a streptavidin-magnetic bead separation method that is part of the Atlas Pure Total RNA Labeling system. The labeled probes from each sample were hybridized with the plastic human 8K gene arrays for about 16 hours, the arrays were washed and imaged according to the Atlas array protocols. The Atlas image 2.7 software was used to align array images with the array grid template and to exclude false background signals or false signals due to strong signal bleedover. The transcript signals were then extracted from these aligned arrays using the Atlas Image 2.7 software and further statistical analysis of the changes in gene expression were performed.  
         [0092]     In general, mRNA transcription was assayed, by hybridization to suitable oligonucleotide probes. In a few cases, e.g., for CK19 and amylase, the protein expression product was measured, using conventional methods of immunohistochemistry. A summary of the expression by these cell populations of a selected set of genes is presented in Table 4. Table 4 contains a list of genes expressed in IP cells and a comparison of expression patterns in primary acinar cells and primary ductal cells. Gene products identified as “+” were expressed; those identified as “++” were strongly expressed. Gene products designated ® are found in regenerating pancreas.  
                           TABLE 4                                   Primary                   Acinar       Gene   IP Cells   Primary Ductal Cells   Cells                   Aquaporin 1   +   ++(mRNA)/+(protein)   0       Aquaporin 5   ++   +(mRNA)/−(protein)       Aquaporin 8   +   −   +       Insulin Receptor Substrate-2   +   ++ ®       Protein Kinase B (AKT)   0   +   +       Calpain (mu)   ++   −   ++       CFTR (Cystic Fibrosis   0   0   0       Transmembrane       Conductance Regulator)       Claudin 2   nd   ++   −       Claudin 3   +   +   +       Claudin 4   +   +   +       Claudin 5   nd   −   ++       Carbonic Anhydrase II   0   0   0       Inositol 1,4,5 triphosphate   ++   −   ++       Rc, Type 3       MUC-1   +   ++   +       MUC-6   ++   +       Cytokeratin 7   ++   ++   −       Cytokeratin 8   ++   +       Cytokeratin 18   +   +       Cytokeratin 19   +   ++   −       alpha v integrin   0   +       alpha 3 integrin   ++   n/a       beta 3 integrin   0   +       beta 4 integrin   +   n/a       beta 5 integrin   0   +       fibronectin   0   +       collagen IV   +   +       vitronectin   0   + ®       MMP2   0   Trace       MMP9   +   Trace       TIMP1   ++   Trace       TGF-alpha   Trace   ++ ®       Gastrin   0   ++ ®       ICAM-1   0   0       ICAM-2   0   0       ICAM-3   0   0       Pancreatitis Associated   ++   + ®   Trace       Protein (PAP)       Reg-1   +   0   Trace       pyrimidinergic receptor P2Y   +   +       Syndecan   +   +(low)   Trace       Glutathione S Transferase-   +   +   −       pi                  
 
 II. Transformation of Glandular Epithelial Cells into Insulin Producing Cells—Generating Insulin-Producing Cells by Differentiation of IP Cultures (Culture Phase II) 
 
         [0093]     IP cultures can be utilized to generate insulin-producing cells by placing the cells in a second phase of culture that includes a surface, such as Collagen I, that promotes attachment of the IP cells combined with a defined medium formula that lacks serum but contains combinations of the following differentiation promoting factors: Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), and VEGF. In the following examples, the base medium is composed of a 1:1 mixture of HamsF12 and DMEM with antibiotics and 0.2% Bovine Serum Albumin (Fraction V, heat inactivated 99% pure). In one example (Combination 1), the base medium contained Cholera Toxin B, Dexamethasone, GRP, GLP-1, Glucose, IGF-1, IGF-2, Insulin, Prolactin, Sonic Hedgehog, Trolox, aFGF, and bFGF. In another example (Combination 2), the base medium contained Activin A, CGRP-alpha, CNP, Glucose, GLP-1, IGF-2, Insulin, LIF, Met-Enkephalin, Prolactin, Sonic Hedgehog, aFGF, and vEGF. In a third example (Combination 3), the base medium contains Activin A, CGRP-alpha, Cholera Toxin B, Dexamethasone, Glucose, GLP-1, Insulin, LIF, Laminin, Met-Enkephalin, PDGFAA/BB, Sonic Hedgehog, Substance P, TGF-alpha, aFGF, and VEGF. The concentrations of these media supplements are listed in Table 1.  
         [0094]     AD cells were placed into culture by either: 1) trypsinizing the cells from the surface on which they were generated, and redistribution onto a fresh attachment-promoting surface at a density of ˜5×10 4  cells/cm 2 , or 2) removing the medium, washing 2× in PBS to remove traces of old medium, and cultures re-fed with the new medium (described above) containing differentiation promoting factors. Cells are cultured for a period of 4-10 days at 37° C. and 21% oxygen. On Day 5, half of the medium is removed and replaced with an equal volume of fresh medium containing differentiation promoting factors.  
         [0000]     Phenotypic Analysis of IP Cells After Differentiation Culture.  
         [0095]     Morphological assessment of IP cells cultured in differentiation conditions described above was captured by light microscopy (see Example 8, below). The cellular phenotype of the cells comprising these cultures was assessed by immunocytochemistry as described above using monoclonal antibodies to vimentin, pro-insulin, C-peptide, MUC-1, and CK19 (See Example 10, below). Briefly, cultures were fixed with 10% formalin for 1 hour at room temperature, then washed with PBS and subjected to immunocytochemical protocol. (See Example 9, below).  
         [0000]     Functional Analysis of IP Cells After Differentiation Culture.  
         [0096]     The ability of the aggregated cell clusters to release insulin and C-peptide was assessed by subjecting the cultured cells to a glucose challenge as follows. Cells that had been cultured in differentiation medium for 7-10 days were washed 3× in PBS, then re-fed with either 1) base medium (described above) with 5 mM Glucose, or 2) base medium with 22 mM glucose. After 18 hours, the cell-conditioned medium was collected and subjected to ELISA analysis for insulin and C-peptide release (Diagnostic Systems Laboratories (DSL)). ELISAs were conducted using the standard range assay procedure according to manufacturer&#39;s specifications. Plates were incubated on a shaker during the assay and results were read in a Tecan spectrophotometric plate reader. Total ng of insulin or C-peptide per well were calculated for each media condition, for both 5 mM glucose media and 22 mM glucose media (See Example 10).  
       Example 8  
       [0097]     Pancreatic acinar cells were cultured in Base Medium+ITS+Serum (10%) for 1 week, then trypsinized (treated with 0.25% Trypsin without EDTA for 10 minutes at 37° C.) and transferred to a fresh collagen-1 coated surface and placed in a medium containing all 23 DFPs listed. Over a period of 3-5 days, the cells readily formed three-dimensional pod-like structures, clearly observable by light microscopy ( FIG. 11 ). Some larger pods detached from the culture surface after about 4-6 days in culture, and remained viable, as determined by trypan blue exclusion. The pod-like structures were hypothesized to be aggregations of insulin-producing cells, and subjected to further analysis as described below.  
       Example 9  
       [0098]     Pod-like structures, generated the same manner as described in the previous example, were fixed in 10% formalin and subjected to immunocytochemical analysis first with CK19 monoclonal antibodies, then with C-peptide monoclonal antibodies, as described above.  FIG. 12A  shows a group of cells (DAPI stained nuclei are blue), some of which are immunopositive for CK19 (green staining).  FIG. 12B  shows the same group of cells, many of which are positive for C-Peptide, which is produced when the proinsulin molecule synthesized within the cell is cleaved to yield mature insulin; the C-peptide stained cells are red, with a typical granular staining of the cytoplasm.  FIG. 12C  shows a higher power overlay image, demonstrating colocalization of CK19 and C-peptide in a small subset of cells. Co-stained cells appear yellow-orange on the overlay image.  
       Example 10  
       [0099]     Cells cultured in base medium (negative control), or in Combinations 1, 2 and 3 of the differentiation promoting media, were evaluated for their ability to release insulin and C-peptide into the culture medium. In addition, we assessed whether increasing concentrations of glucose led to the release of a greater quantity of insulin and C-peptide, indicating an islet-like functionality. First, the cells were cultured for 1 week in base medium+EGF(10 ng/ml)+ITS+10% fetal bovine serum (PCM). Then, cells were either subjected to a wash and medium change (non-subcultured), or to a wash, trypsinization/detachment, reseeding, and medium change. Replicate cultures were re-fed with either base medium (serum-free), fresh PCM, or one of the three combinations of differentiation promoting media (all serum-free). After 10 days, differentiation media were removed, cultures were washed 3× with PBS, then re-fed with serum-free base medium containing either 5 mM glucose or 22 mM glucose (final concentration). After 18 hours, the conditioned media were collected and subjected to ELISA analysis with antibodies to either Insulin or C-Peptide (DSL laboratories).  FIGS. 13A, 13B  and  13 C, respectively, show insulin release by nonsubcultured cells, and insulin release and C-peptide release in response to glucose challenge. Since some of the cultures contain insulin, and cells can take insulin up from the medium, production of C-peptide is an important confirmation that the cells are synthesizing insulin de novo from the synthesis and processing of proinsulin. Furthermore, the production of insulin and C-peptide is increased in most cases with increasing glucose concentration, suggesting an islet-like function of cells within these cultures. Note that little insulin or C-peptide is produced in the base medium that contains no DPFs.  
       Example 11  
       [0100]     Both the quantity of insulin and the quantity of DNA were measured in IP cells subjected to differentiation culture with or without enzymatic detachment and subculturing. Cultures were carried out precisely as described in the previous paragraph. DNA was measured utilizing a standard Picogreen assay (Molecular Probes), while insulin was measured by ELISA assay. Total ng of Insulin was divided by total μg of DNA in the sample, thus providing the insulin:DNA ratio value, in order to calculate a ratio of the quantity of insulin present vs. the number of cells present (reflected by DNA content). The results are shown in  FIG. 14 . In each of the differentiation media combinations, the insulin:DNA ratio is increased compared to base medium, suggesting that more insulin is produced on a per cell basis in the presence of DPFs than when cultured without them. Furthermore, the insulin:DNA ratio is increased slightly in some conditions upon glucose challenge (22 mM glucose vs. 5 mM), suggesting that the cells respond to glucose by releasing a greater quantity of insulin.  
       Example 12  
       [0101]     Insulin-producing cells obtained by the preceding method were subjected to gene expression analysis as described above. Table 5 contains a list of the highest expressed genes, their position on the Clontech atlas 8K gene array, and relative expression of these genes (after normalization). Table 5 is attached hereto as Appendix 1.  
       Example 13  
       [0102]     Primary human pancreatic cells were seeded at 0.5×10 5  cells/cm 2  in PCM on a collagen-1 surface and grown for 7 days. Insulin was measured at Days 1, 7, and 10 as follows: Growth medium was removed, wells were washed 3× in phosphate buffered saline. After a pre-incubation for 1 hour at 37 C in base medium without insulin, with 5 mM glucose, media was removed and replaced with either 1) base medium (without insulin) with 5 mM glucose, or 2) base medium (without insulin) with 22 mM glucose. Insulin was measured in cell-conditioned media after 18 hours at 37° C. After 7 days of culture, PCM medium was replaced with either 1) fresh PCM, 2) serum-free base medium, 3) serum free base medium with all 23 differentiating factors, 4) serum-free combination 1, or 5) serum-free combination 2. The results are shown in  FIG. 15 . After 3 days exposure to the differentiating factors, increased insulin release is noted in presence of differentiating factors. The results on Day 1 argue against the presence of a significant number of insulin-producing cells in the starting material demonstrating the de novo generation of insulin-producing cells from acinar cells in the primary culture. It can be seen in the Figure that at the end of 10 days, insulin release in response to a glucose challenge is much greater in the DFP media than in the PCM or base medium, verifying the stimulatory effect that the DFPs exert on transformation of glandular epithelial cells into insulin-producing cells.  
       Example 14  
       [0103]     Human pancreatic acinar cells were cultured on a collagen I surface in PCM from Day 1 to Day 7, thus generating a culture of IP cells at Day 7. On Day 7, the IP cells were washed and the PCM medium was replaced with the G09 differentiation medium containing the 30 factors listed in Table 2. At each time point (Days 1, 7, 10 and 14), insulin release was measured by washing the cultures three times with PBS, then challenging the cultures with a 1:1 mixture of DMEM and HAMs F12 containing either 5 mM or 22 mM glucose. After 18 hours of exposure to the glucose, supernatants were collected and insulin measured by ELISA. The results are shown in  FIG. 15   a.    
         [0000]     III. Expression Studies at Several Time Points of Primary Human Acinar Cells that are Expanded, Allowed to Differentiate into IP Cells and then Allowed to Differentiate Further into Insulin-Producing Cells  
       Example 15  
       [0104]     Three independent samples of primary human pancreatic acinar cells were seeded and expanded described above. From Day 0 to Day 8, cells were on collagen I surface, seeded at 10 4  cells/cm 2 , in PCM. On Day 8, the medium was changed from PCM to the medium with the active factors shown in Table 2. Cells were fed twice with G09 (50% of medium replaced) between days 8 and 16. The cells remained on the surface throughout the culture process. Cultures were harvested at 3 days after the initial plating (actively trans-differentiating acinar cells), 8 days after plating (IP cells) and 16 days after plating (putative insulin producing cells) and subjected to gene expression analysis, as described in Example 7. mRNA expression data were obtained with 12K microarrays from Clonetech.  
         [0105]     Briefly, growth medium was removed from the culture flasks and cells were lysed in trizol LS (Invitrogen) chaotrope/phenol reagent for about 2 minutes by pipetting the lysis solution over the cell layer. Three ml of RNAse free water was added per 9 ml of lysis solution in an Oak Ridge Cetrifuge tube. 2.4 ml chloroform was then added and the solution vigorously vortexed for 1 minute. The aqueous and organic phases were then separated by cetrifugation at 4° C. and the upper aqueous phase containing RNA was removed to a clean PET tube. The RNA was precipitated by isopropanol precipitation, washed with 70% ethanol and redissolved in 200 μl of RNAse free water. A chaotrope lysis reagent was immediately added to the RNA and it was further purified using a Qiagen spin column method with a DNAse digestion step. The purified RNA was finally eluted in 80 μl RNAse free water and stored at −80° C.  
         [0106]     Labelled P-33 cDNA probes were prepared from the 30 μg of total RNA from each sample by first enriching for poly A+RNA using a streptavidin-magnetic bead separation method that is part of the Atlas Pure Total RNA Labeeling system. The labeled probes from each sample were hybridized with the plastic human 12 K gene arrays for about 16 hours, the arrays were washed and imaged according to the Atlas array protocols. The Atlas image 2.7 software was used to alighn array images with the array grid template and to exclude false background signals or false signals due to strong signal bleedover. The transcript signals were then extracted from these aligned arrays using the Atlas Image 2.7 software and further statistical analysis of the changes in gene expression were performed.  
         [0107]     The raw expression data were analyzed as follows: (1) We filtered out genes that were not expressed at any of the 3 conditions/time points; (2) We normalized all of the microarrays against each other to remove differences from array-to-array and the effects of variability in sample processing, hybridization, etc.; (3) We identified genes which showed a statistically significant difference among the conditions/time points; and (4) We clustered the genes based on their temporal patterns in a way that is consistent with the design of the study and the changes in phenotype.  
         [0108]     Table 6 shows expression data for the genes that were identified by the above analysis. This Table is attached hereto as Appendix 2. These identified genes were expressed at high levels at both Day 3 and Day 8, or their expression increased substantially between Day 3 and Day 8. The Table also shows the expression levels of these genes at Day 16, and the mean expression for all three condition/time points. The Table also shows the ratios of expression at various times: “I to A” is the ratio of expression of putative insulin-producing cells (Day 16) to acinar (Day 8) cells; “Int to A” is the ratio of IP cells (Day 8) cells to acinar cells (Day 3).  
         [0109]     The data shown in Table 6 were further analyzed by clustering them into one of 17 “classes,” whose features are summarized on the Table. A graphical representation of the characteristics of these 17 classes in presented in  FIG. 16 .  
         [0110]     The data from the Day 8 time points in Table 6 were also grouped with regard to whether the genes expressed at Day 8 in these cells belong to the classes of genes expressed normally in (1) liver and pancreas; (2) pancreas-associated genes; (3) liver-associated genes; or (4) progenitor-associated genes. The results are shown in Table 7.  
                                                                   TABLE 7                       BDT Intermediate Cells                                                    Pancreatic Pattern of           Sample 1   Sample 2   Sample 3   Hepatic Pattern of Expression   Expression               Genes Expressed in Liver       and Pancreas       CK18   +   +   +   hepatic lineage   acinar cells       CK8   +   +   +   hepatic lineage   acinar cells       CK19   +   +   +   bile duct   duct cells       CK7   +   +   +   bile duct   duct cells       HNF1   +   +   +   liver tc factor   in beta cells       α-1 antitrypsin   ++   ++   ++   produced in differentiated hepatocytes   yes       Notch-1   −   −   Trace   involved in differentiation of cells into   developing pancreatic                       hepatic lineage   epithelium       α-fetoprotein   −   −   −   developing hepatocytes and hepatic   developing pancreatic                       progenitors   ducts       Notch-3   Trace   Trace   Trace   involved in differentiation of cells into   pancreatic mesenchyme                       hepatic lineage   and endothelium       Notch-4   Trace   Trace   Trace-   involved in differentiation of cells into   pancreatic mesenchyme                       hepatic lineage   and endothelium       Jagged-2   +   +   +   involved in differentiation of cells into   yes                       hepatic lineage       pi-glutathione s transferase   +   +   ++   developing liver   duct cells and centroacinar       (pi-GST)                   cells       γ-glutamyl transferase   −   −   −   developing bile duct   acinar cells       Pancreas-Associated Genes       carbonic anhydrase   −   −   Trace   no   duct cells       CF transmemb conductance   −   −   Trace   no   duct cells       regulator       elastase   −   −   −   no   acinar cells       amylase   −   −   −   no   acinar cells       insulin   +   Trace   Trace   no   islet       somatostatin   Trace   Trace   Trace   no   islet       Pancreatic Polypeptide   +   +   Trace   no   islet       Glucagon   −   −   −   no   islet       Liver-Associated Genes       Sialyltransferase-6   −   −   −   produced in differentiated hepatocytes   no       Liver-specific bHLH   +   +   +   liver-specific Tc factor   no       transcrip factor       Thy-1   +   +   +   hepatic oval cell marker   no       Glucose-6-phosphatase   −   −   Trace   hepatic lineage, progenitors and adult   No       Glutamine synthetase   −   −   Trace   hepatocyte   No       Carbamoyl phosphate   −   −   −   hepatocyte   no       synthetase-1       Dipeptidylpaptidase IV   −   −   −   hepatocyte   no       C/EBP-α   ++   ++   +   liver-specific Tc factor   *turned on and upregul                           during hepatization of                           pancreas (copper-deficient                           diet)       C/EBP-beta   ++   ++   ++   liver-specific Tc factor   *turned on and upregul                           during hepatization of                           pancreas (copper-deficient                           diet)                        Progenitor Cell-Associated Genes   Sample 1   Sample 2   Sample 3   Tissue                       Musashi-1   −   −   −   Intestine           Nestin   −   −   −   Pancreas/Neuronal           CD34   −   −   −   Hematopoietic           Thy-1   −   −   −   Hepatic progenitors           BMP-2   −   −   −   Neuronal           BMPRclA   −   −   Trace   Mesenchyme           c-kit   −   −   −   Liver/Pancreas/Neuronal           chromogranin A   Trace   Trace   Trace   Neuroendocrine/Liver/Intestine           PDX-1   −   −   +   Pancreas                      
 
         [0111]     As can be seen, at Day 8 IP cells no longer expressed genes consistent with pancreatic acinar cells, nor did they express a complement of genes specific for pancreatic ductular cells. The IP cells expressed low levels of some markers associated with pancreatic islets, including insulin, somatostatin and pancreatic polypeptide, suggesting that at least some cells in the population are competent to express endocrine genes of the pancreatic islets.  
         [0112]     Surprisingly, the IP cells also expressed several liver-specific transcription factors (e.g., C/EBP alpha, C-EBP-beta) and other markers of mature and developing liver, including low levels of Thy-1, a marker associated with hepatic “oval” stem cells. This suggests that the differentiating cells were not moving simply from pancreatic acinar to pancreatic ductal, but had developed into a cell with both hepatic and pancreatic characteristics, while not fitting into any single gene expression profile of one of these cell types. The cells generated in this example resemble the cells that emerge from the pancreas of rodents that are fed a copper-deficient diet. (See, e.g. Rao et al., 1988). The pancreas of such animals goes through an acute phase of pancreatitis followed by “hepatization” of liver (which means cells that begin to express hepatic genes rather than pancreatic genes). Liver-like cells have also been reported in human fetal pancreas (Tsanadis et al., 1995) Isolated cells generated by the methods of the present invention (e.g., by propagating primary acinar cells or other types of endodermal cells or progenitor cells by the methods of the invention) are to be distinguished from naturally occurring cells that may have some of the characteristics of IP cells, such as oval cells or cells isolated from the pancreas of a rodent on a copper-deficient diet.  
         [0113]     Cells having the characteristics of these IP cells may be useful for, e.g., therapeutic approaches in the treatment of diabetes. Furthermore, although the cells in this example were derived from pancreas, other epithelial tissues, or perhaps even any endoderm-derived tissue, may provide additional sources of cells that can be differentiated into cells having a similar phenotype. Suitable tissue types include, e.g., liver or intestine. These IP cells express genes associated with pancreas, liver, intestine and neuronal tissues. For example, they express mucin, CK19 and CK7, which are common markers associated with duct cells in the pancreas, liver and intestine. Thus, the gene expression pattern seen in these IP cells may serve as a predictive measure for cells derived from each of these tissues for the purpose of generating insulin-producing cells. Furthermore, IP cells may, under appropriate conditions, give rise, not only to pancreatic islet cells, but also to hepatocytes or any endoderm-derived tissue.  
         [0114]     The disclosures of the following references, cited above in part, relate to the present invention: 
    WO 02/29010 A2 (Kerr-Conte);     Bonner-Weir, S. et al., Proc. Natl. Acad. Sci. USA 97: 7999-8004 (2000),     Bouwens, L., Microsc. Res. Tech. 43: 332-6 (1998),     Bowens, L. et al. Diabetologia 41:629-33 (1998);     Gmyr, V. et al., Diabetes 49:1671-80 (2000);     Gmyr, V. et al. Cell Transplant 10:109-21 (2001),     Gmyr, V. et al. Diabetes 49:1671-80 (2000),     Hall, P. A. et al., J. Pathol. 166: 97-103 (1992);     Kerr-Conte, J. et al., Diabetes 45:1108-14 (1996);     Kerr-Conte, J. et al., Transplant Proc 27:3268 (1985);     Pattou F. et al., Bull. Acad. Natl. Med. 184:1887-99 (2000);     Rao, M S et al Biochem Biophys Res Comm. 156:131-6 (1988);     Rooman, Ilse et al., Diabetes 51: 686-90 (2002);     Rooman, I, et al. Diabetologia 43:907-14 (2000);     Rooman, I. et al., Gastroenterology 121: 940-9 (2001);     Trivedi, N. et al. Endocrinology 142:2115-22 (2001);     Tsanadis, G. et al. Histol. Histopathol. 10:1-10 (1995);     Wang, R. N. et al., Diabetologia 38:1405-11(1995);     U.S. Pat. No. 6,011,647 (Ammon Peck).    
 
         [0134]     The embodiments illustrated and discussed in the present specification are intended only to teach those skilled in the art the best way known to the inventors to make and use the invention, and should not be considered as limiting the scope of the present invention. The exemplified embodiments of the invention may be modified or varied, and elements added or omitted, without departing from the invention, as appreciated by those skilled in the art in light of the above teachings. It is therefore to be understood that, within the scope of the claims and their equivalents, the invention may be practiced otherwise than as specifically described.  
         [0135]     The entire disclosure of all applications, patents and publications, cited above and in the figures are hereby incorporated in their entirety by reference.  
                                                                 Position on   Relative Expression,   Relative Expression,       GENE   Atlas 8K Array   Sample 1   Sample 2                                aquaporin 5   7547   4539   4550       actin, beta   3952   3598   3442       actin, beta   8176   3047   3747       growth hormone secretagogue receptor   6846   2092   1710       profilin 1   448   1580   1246       special AT-rich sequence binding protein 1   3035   1437   886       (binds to nuclear matrix/scaffold-       associating DNA&#39;s)       cardiac-specific homeo box   2050   1395   2850       CCAAT/enhancer binding protein (C/EBP),   1588   1374   1671       beta       RAS guanyl releasing protein 2 (calcium   8262   1263   1616       and DAG-regulated)       cartilage paired-class homeoprotein 1   6677   1166   1241       paired-like homeodomain transcription   6805   1113   756       factor 1       transcription factor 21   7621   1063   801       CD3E antigen, epsilon polypeptide (TiT3   8054   994   1113       complex)       CD151 antigen   5613   935   808       ATPase, Ca++ transporting, plasma   7940   919   876       membrane 2       ficolin (collagen/fibrinogen domain-   824   901   829       containing) 3 (Hakata antigen)       inositol polyphosphate phosphatase-like 1   5989   832   425       protein tyrosine phosphatase, receptor   8367   806   810       type, S       integrin, alpha 3 (antigen CD49C, alpha 3   1743   758   647       subunit of VLA-3 receptor)       syntaxin 1A (brain)   6851   743   658       parathymosin   7135   725   852       thymosin, beta 10   7436   709   1617       midkine (neurite growth-promoting factor 2)   2470   682   802       arylsulfatase A   3147   678   3084       calbindin 2, (29 kD, calretinin)   7000   676   786       serine (or cysteine) proteinase inhibitor,   5214   668   678       clade A (alpha-1 antiproteinase,       antitrypsin), member 1       retinal G protein coupled receptor   7972   653   696       myosin regulatory light chain 2, smooth   2499   638   561       muscle isoform       butyrate response factor 1 (EGF-response   7325   630   646       factor 1)       type I transmembrane receptor (seizure-   7583   589   394       related protein)       type I transmembrane receptor (seizure-   7583   589   394       related protein)       procollagen C-endopeptidase enhancer   3593   576   713       mitogen-activating protein kinase kinase   7069   558   571       kinase kinase 2       protease, serine, 1 (trypsin 1)   6323   558   656       pancreatitis-associated protein   4576   536   2177       angiotensin receptor 1B   4093   516   491       stratifin   6489   503   581       keratin 17   7903   500   364       somatostatin receptor 3   6872   432   433       myosin-binding protein H   4692   428   96       ephrin-A5   4202   411   381       RAP1, GTPase activating protein 1   1965   407   263       chymotrypsinogen B1   6604   405   830       ankyrin-like with transmembrane domains 1   3577   395   431       Misshapen/NIK-related kinase   2439   391   341       bone morphogenetic protein 6   4492   381   308       spllcing factor proline/glutamine rich   713   375   662       (polypyrimidine tract-binding protein-       associated)       claudin 12   2720   370   378       matrix metalloproteinase 23A   7491   368   138       neurogranin (protein kinase C substrate,   4465   366   335       RC3)       dopamine receptor D2   1649   362   234       cardiotrophin 1   5283   359   507       CCAAT/enhancer binding protein (C/EBP),   7237   359   645       alpha       paired box gene 9   5206   335   201       protein tyrosine phosphatase, receptor   8235   331   250       type, N       keratin 8   7215   327   449       claudin 7   280   325   173       trophinin associated protein (tastin)   462   323   360       neuronal thread protein   8356   322   366       basic helix-loop-helix domain containing,   6734   318   215       class B, 2       annexin A2   4467   290   226       cathepsin D (lysosomal aspartyl protease)   7370   289   600       Bicaudal D ( Drosophila ) homolog 1   6822   284   217       lectin, galactoside-binding, soluble, 1   7331   280   310       (galectin 1)       keratin 7   7171   278   481       glyceraldehyde-3-phosphate   3953   278   307       dehydrogenase       aquaporin 6, kidney specific   7591   277   258       TNF receptor-associated factor 1   6037   269   270       Rho GDP dissociation inhibitor (GDI) alpha   5565   267   321       calcium channel, voltage-dependent,   3142   260   207       gamma subunit 4       glutamate receptor, ionotropic, kainate 1   4776   244   296       CCR4-NOT transcription complex, subunit 4   983   244   428       filamin A, alpha (actin-binding protein-280)   3457   241   233       peanut ( Drosophila )-like 1   711   233   310       enhancer of rudimentary ( Drosophila )   5921   231   405       homolog       endothelin converting enzyme 1   7835   229   197                 rotocadherin 17   2483   223   208                 quaporin 8   7679   217   145                 ynapsin I   4871   216   164                 ubulin, alpha, brain-specific   2827   212   345                 D44 antigen (homing function and Indian   7848   207   141                 lood group system)                 erebral cavernous malformations 1   2731   205   116                 sulin-like 3 (Leydig cell)   666   202   365                 denylate cyclase activating polypeptide 1   4489   200   74       pituitary)                 airless (mouse) homolog   5185   196   36                 sulin   4427   190   44                 ranulin   928   184   201                 ranulin   928   184   201                 arly growth response 1   2111   178   136                 yclin-dependent kinase inhibitor 1A (p21,   7852   175   108                 ip1)                 tem cell growth factor; lymphocyte   1606   174   152                 ecreted C-type lectin                 D4 antigen (p55)   5608   172   143                 CTAIRE protein kinase 1   6334   161   78                 ho GTPase activating protein 6   1035   160   220       G protein-coupled receptor 37 (endothelin   6318   158   35                 eceptor type B-like)                 yndecan 4 (amphiglycan, ryudocan)   3154   157   147                 CTAIRE protein kinase 3   8050   155   159                 mpty spiracles ( Drosophila ) homolog 2   2084   150   207                 ransglutaminase 1 (K polypeptide   6674   150   101                 pidermal type I, protein-glutamine-gamma-       glutamyltransferase)       potassium voltage-gated channel,   1335   147   62       subfamily G, member 2       aldehyde dehydrogenase 4 (glutamate   5985   147   207       gamma-semialdehyde dehydrogenase;       pyrroline-5-carboxylate dehydrogenase)       E1A binding protein p300   1433   144   197       LIM homeobox transcription factor 1, beta   8211   143   89       eukaryotic translation elongation factor 2   4536   134   150       mitogen-activated protein kinase kinase   5462   129   92       kinase 10       PPAR(gamma) angiopoietin related protein   3074   129   56       homeo box A5   7037   128   87       CD63 antigen (melanoma 1 antigen)   7769   124   91       nuclear receptor coactivator 3   4181   119   84       CD68 antigen   443   118   256       transmembrane 4 superfamily member 7   1571   117   29       pancreatic polypeptide   2735   116   136       endothelin type b receptor-like protein 2   6656   114   74       neurogenin 1   5772   113   91       insulin receptor substrate 2   6016   110   130       glutamate receptor, ionotropic, N-methyl D-   4702   109   58       asparate-associated protein 1 (glutamate       binding)       neurotrophin 5 (neurotrophin 4/5)   8259   108   89       pyrimidinergic receptor P2Y, G-protein   3857   105   65       coupled, 6       empty spiracles ( Drosophila ) homolog 1   2040   103   87       chromobox homolog 2 ( Drosophila  Pc   2832   101   139       class)       heart and neural crest derivatives   2146   92   129       expressed 1       transglutaminase 2 (C polypeptide, protein-   7731   92   74       glutamine-gamma-glutamyltransferase)       enolase 1, (alpha)   1389   92   205       thyroid transcription factor 1   4519   89   60       keratin 19   5923   88   223       Deleted in split-hand/split-foot 1 region   3641   87   104       glutathione peroxidase 4 (phospholipid   1874   84   72       hydroperoxidase)       aristaless ( Drosophila ) homeobox   1783   81   103       GATA-binding protein 4   659   80   110       transcription factor 1, hepatic; LF-B1,   712   80   136       hepatic nuclear factor (HNF1), albumin       proximal factor       heat shock transcription factor 1   6708   79   57       liver-specific bHLH-Zip transcription factor   765   77   188       liver-specific bHLH-Zip transcription factor   765   77   188       eukaryotic translation initiation factor 3,   6280   76   94       subunit 4 (delta, 44 kD)       eukaryotic translation initiation factor 3,   6280   76   94       subunit 4 (delta, 44 kD)       gamma-aminobutyric acid (GABA) A   3720   70   178       receptor, alpha 6       retinoic acid receptor, gamma   5191   70   109       homeo box D9   1776   69   34       MAD1 (mitotic arrest deficient, yeast,   1946   63   38       homolog)-like 1       homeo box A4   7177   57   103       Thy-1 cell surface antigen   559   57   87       talin   603   53   84       bone morphogenetic protein receptor, type   332   53   45       II (serine/threonine kinase)       hepatocyte nuclear factor 3, alpha   72   52   60       ryanodine receptor 2 (cardiac)   5244   47   40       signal transducer and activator of   3661   40   35       transcription 6, interleukin-4 induced                  
 
         [0136]     Appendix 2:  
                                                                                                     TABLE 6                       SwissProt   Spot   geneName   day3   day8   day16   allMean   ratioItoA   rationIntto/   classID   classsName                                P04270   E19ab2   actin; alpha; cardiac muscle   1198.174   760   5955.077   2637.676   2.31E+00   −8.57E−01   7   Equal A/Int; Up Islets       O95996   N17ab2   adenomatous polyposis coli like   2708.542   5180   7594.139   5161.464   1.49E+00   9.36E−01   7   Equal A/Int; Up Islets       Q14697   G02ef8   alpha glucosidase II alpha subun             306.0691   350   775.3358   477.9123   1.34E+00   1.92E−91   7   Equal A/Int; Up Islets       P14209   G23ab7   antigen identified by monoclonal   389.822   507   1238.43   711.8924   1.67E+00   3.80E−01   7   Equal A/Int; Up Islets       P30530   G14ef5   AXL receptor tyrosine kinase   314.4639   288   634.5658   412.2115   1.01E+00   −1.29E−01   7   Equal A/Int; Up Islets       O43770   I23ab3   B-cell CLL/lymphoma 7C   700.573   1050   1504.52   1085.931   1.10E+00   5.87E−01   7   Equal A/Int; Up Islets       O43852   P08ab3   calumenin   801.582   1290   4720.807   2269.921   2.56E+00   6.84E−01   7   Equal A/Int; Up Islets       O75718   O24cd6   cartilage associated protien   430.4432   256   1090.59   592.2327   1.34E+00   −7.52E−01   7   Equal A/Int; Up Islets       Q9Y3C0   G14ef2   CGI-116 protein   181.0293   301   416.7246   229.7237   1.20E+00   7.36E−01   7   Equal A/Int; Up Islets       P78369   G09cd6   claudin 10   1176.087   742   2598.595   1505.471   1.14E+00   −6.65E−01   7   Equal A/Int; Up Islets       P08572   P08ef6   collagen; type IV; alpha 2   1130.23   1350   4684.425   2389.488   2.05E+00   2.60E−01   7   Equal A/Int; Up Islets       P11802   B05ef5   cyclin-dependent kinase 4   914.1579   978   2342.994   1411.839   1.36E+00   9.79E−02   7   Equal A/Int; Up Islets       Q16555   O07ab4   dihydropyrimidinase-like 2   114.6165   164   921.1473   399.8267   3.01E+00   5.14E−01   7   Equal A/Int; Up Islets       P33316   H23ab5   dUTP pyrophosphatase   177.2032   238   541.5382   318.7836   1.61E+00   4.23E−01   7   Equal A/Int; Up Islets       P07992   K20ef6   excision repair cross-complemen             362.031   415   907.7933   561.6388   1.33E+00   1.97E−01   7   Equal A/Int; Up Islets       O75636   B14cd3   ficolin (collagen/librinogen doma             1081.127   1010   4327.606   2139.448   2.00E+00   −9.87E−02   7   Equal A/Int; Up Islets       Q9UBA6   B19ef4   G8 protein   379.6842   578   1489.206   812.6378   2.01E+00   6.41E−01   7   Equal A/Int; Up Islets       Q9Y5P5   P08ef7   GDP-mannose pyrophosphoryta             171.1216   198   414.0862   261.0679   1.27E+00   2.10E−01   7   Equal A/Int; Up Islets       O75293   E02ef7   growth arrest and DNA-damage-             194.3626   203   386.6833   261.3841   9.92E−01   6.35E−02   7   Equal A/Int; Up Islets       P50152   C05ab6   guanine nucleotide binding prote             204.743   150   497.3097   283.8702   1.28E+00   −4.53E−01   7   Equal A/Int; Up Islets       Q9NX09   C05gh3   HIF-1 responsive RTP801   348.8574   253   1032.929   545.0822   1.57E+00   −4.61E−01   7   Equal A/Int; Up Islets       P05204   J22ab7   high-mobility group (nonhistone              2067.865   1120   6059.895   3082.818   1.55E+00   −8.84E−01   7   Equal A/Int; Up Islets       Q9P0P2   C17ef3   homolog of yeast MOG1   325.8407   378   682.7568   462.1583   1.07E+00   2.14E−01   7   Equal A/Int; Up Islets       Q9NWF8   L15gh2   hypothetical protein FLJ10055   172.167   241   374.3   262.6222   1.12E+00   4.88E−01   7   Equal A/Int; Up Islets       Q9NWV4   B17gh2   hypothetical protein FLJ20580   221.4432   280   483.5381   328.2481   1.13E+00   3.37E−01   7   Equal A/Int; Up Islets       Q9P0S8   A21ef3   hypothetical protein HSPC195   153.824   165   330.9111   216.4274   1.11E+00   9.72E−01   7   Equal A/Int; Up Islets       Q9BWS9   P04gh5   hypothetical protein MGC3234   196.9154   161   427.2066   261.7132   1.12E+00   −2.90E−01   7   Equal A/Int; Up Islets       Q9BSK0   K21gh8   hypothetical protein MGC4415   156.4692   117   684.3425   319.1224   2.13E+00   −4.25E−01   7   Equal A/Int; Up Islets       Q9Y6M1   P09cd6   IGF-II mRNA-binding protein 2   135.2566   153   408.5101   232.2937   1.59E+00   1.79E−01   7   Equal A/Int; Up Islets       Q9NQX7   H02gh7   Integral membrane protein 3   478.2728   481   1102.244   687.2575   1.20E+00   8.97E−03   7   Equal A/Int; Up Islets       P08648   E23ef7   Integrin; alpha 5 (fibronectin rece             183.4629   124   478.7266   262.0713   1.38E+00   −5.65E−01   7   Equal A/Int; Up Islets       O00410   J24ab6   karyopherin (importin) beta 3   326.6874   196   629.7656   384.2402   9.47E−01   −7.35E−01   7   Equal A/Int; Up Islets       P07195   N16ab6   lactate dehydrogenase B   1003.971   1200   5593.079   2599.05   2.48E+00   2.57E−01   7   Equal A/Int; Up Islets       P09382   N22ab6   lactin; galactoside-binding; solub   19170.52   35400   78086.75   44205.77   2.03E+00   8.83E−01   7   Equal A/Int; Up Islets       O75427   P20ab6   leucine-rich repeat protein; neur             174.9605   231   543.3883   316.5457   1.63E+00   4.03E−01   7   Equal A/Int; Up Islets       Q16553   A15ab7   lymphocyte antigen 6 complex; I             425.8933   494   938.4504   619.3701   1.14E+00   2.13E−01   7   Equal A/Int; Up Islets       O75900   O05cd4   matrix metalloproteinase 23A   381.2184   297   851.7221   510.1038   1.16E+00   −3.58E−01   7   Equal A/Int; Up Islets       Q9UNF1   H16ef7   melanoma antigen; family D; 2   193.8125   219   659.9701   357.6132   1.77E+00   1.77E−01   7   Equal A/Int; Up Islets       P13995   J16cd6   methylene tetrahydrofolate dehy             321.4878   226   759.6021   435.6746   1.24E+00   −5.09E−01   7   Equal A/Int; Up Islets       O00265   G19cd8   microtubule-associated protein;              189.7616   234   377.5576   267.156   9.93E−01   3.03E−01   7   Equal A/Int; Up Islets       P27361   B13ef5   mitogen-activated protein kinase   358.0872   382   720.3119   486.849   1.01E+00   9.38E−02   7   Equal A/Int; Up Islets       P24844   E18cd6   myosin; light polypeptide 9; regul   5480.451   7380   22518.95   11793.09   2.04E+00   4.29E−01   7   Equal A/Int; Up Islets       Q9NVD4   J10gh2   N-acetylneuraminic acid phosph             153.4762   167   390.6642   237.1908   1.35E+00   1.26E−01   7   Equal A/Int; Up Islets       Q9Y617   N22ef8   phosphoserine aminotransferase   169.9503   250   1238.851   553.0005   2.87E+00   5.58E−01   7   Equal A/Int; Up Islets       O95356   A11gh7   pituitary tumor-transforming 3   237.2126   192   2276.181   901.8229   3.26E+00   −3.05E−01   7   Equal A/Int; Up Islets       Q9Y5X6   G04cd6   plasma glutamate carboxypeptid             169.6268   142   366.6202   226.0168   1.11E+00   −2.58E−01   7   Equal A/Int; Up Islets       Q15113   G20ab8   procollagen C-endopeptidase en             497.3967   402   2628.947   1176.046   2.40E+00   −3.08E−01   7   Equal A/Int; Up Islets       O15460   D20cd4   procollagen-proline; 2-oxoglutar             262.1395   433   756.4003   483.9569   1.53E+00   7.25E−01   7   Equal A/Int; Up Islets       O43556   I19gh1   sarcoglycan; epsilon   172.7191   215   349.304   245.5263   1.02E+00   3.13E−01   7   Equal A/Int; Up Islets       P50454   M17ab6   serine (or cysteine) proteinase in   339.1762   612   4091.161   1680.942   3.59E+00   8.53E−01   7   Equal A/Int; Up Islets       Q92853   A23cd8   similar to vaccinia virus HindIII K             444.062   553   997.4551   664.6951   1.17E+00   3.15E−01   7   Equal A/Int; Up Islets       Q16658   P20cd1   singned-like (fascin homolog; sea   262.7872   479   1472.155   738.014   2.49E+00   8.66E−01   7   Equal A/Int; Up Islets       Q9Y4Y8   E18cd7   Sm protein F   257.2026   278   548.9705   361.3772   1.09E+00   1.12E−01   7   Equal A/Int; Up Islets       Q9BVH9   D18gh7   thioredoxin related protein   522.0262   481   1903.964   968.9954   1.87E+00   −1.18E−01   7   Equal A/Int; Up Islets       Q9HBB0   L08gh8   Thy-1 co-transcribed   327.3502   374   1110.527   603.8101   1.76E+00   1.90E−01   7   Equal A/Int; Up Islets       P01033   P09ef7   tissue inhibitor of metalloproteins   1236.457   1500   13029.41   5256.861   3.40E+00   2.83E−01   7   Equal A/Int; Up Islets       Q15582   L20ef6   transforming growth factor; beta-             1221.083   2060   8540.86   3939.09   2.81E+00   7.51E−01   7   Equal A/Int; Up Islets       Q01995   M07cd2   transgelln   3307.821   3880   18534.27   8573.074   2.49E+00   2.29E−01   7   Equal A/Int; Up Islets       Q13641   B05ab2   trophoblast glycoprotein   479.6488   426   1399.786   768.6158   1.55E+00   −1.70E−01   7   Equal A/Int; Up Islets       P06468   G08cd2   tropomyosin 2 (beta)   339.2292   589   13203.05   4710.469   5.28E+00   7.96E−01   7   Equal A/Int; Up Islets       P51784   M21cd4   ubiquilin specific protease 11   158.0478   194   491.1246   280.9819   1.64E+00   2.94E−01   7   Equal A/Int; Up Islets       P03996   E17ab2   actin; alpha 2; smooth muscle; a             412.1187   1940   41801.34   14717.63   6.66E+00   2.23E+00   9   Increasing A/Int/I       P08123   P02ef6   collagen; type I; alpha 2   186.5666   576   14565.36   5109.251   6.29E+00   1.63E+00   9   Increasing A/Int/I       P24821   A05ef7   hexabrachion (tenascin C; cytota   355.495   918   2371.983   1215.165   2.74E+00   1.37E+00   9   Increasing A/Int/I       Q9NVA2   F13gh3   hypothetical protein FLJ10849   374.1496   861   3471.789   1568.848   3.21E+00   1.20E+00   9   Increasing A/Int/I       P40261   M09cd1   nicotinamide N-methyltransferase   1060.579   2310   5683.533   3016.993   2.42E+00   1.12E+00   9   Increasing A/Int/I       Q15063   C01ef7   osteoblast specific factor 2 (fascl             276.634   795   8328.222   3133.301   4.91E+00   1.52E+00   9   Increasing A/Int/I       P09486   A09ef7   secreted protein; acidic; cysteine   404.2839   2760   63837.2   22333.48   7.30E+00   2.77E+00   9   Increasing A/Int/I       P35625   K20ef5   tissue inhibitor of metalloprotein             216.254   619   10078.17   3637.823   5.54E+00   1.52E+00   9   Increasing A/Int/I       Q9H2L5   G06gh8   AD037 protein   361.2297   681   158.8121   400.4602   −1.19E+00   9.15E+00   19   Int&gt; (A; I)       P15121   C18ab2   aldo-keto reductase family 1; me             2342.744   5380   2337.052   3354.494   −3.51E−03   1.20E+00   19   Int&gt; (A; I)       P08582   B14ef5   antigen p97 (melanoma associat             299.1375   595   80.80392   324.9781   −1.89E+00   9.92E+00   19   Int&gt; (A; I)       P20292   E06ab2   arachidonate 5-lipoxygenase-act   100.0016   687   203.2911   330.0345   1.02E+00   2.78E+00   19   Int&gt; (A; I)       O15342   A13ab3   ATPase; H+ transporting; lysoso             6063.171   16500   6160.831   9572.914   2.31E−02   1.44E+00   19   Int&gt; (A; I)       Q9BXJ0   H18gh6   C1q and tumor necrosis factor re             180.2978   350   154.1441   228.0109   −2.26E−01   9.55E−00   19   Int&gt; (A; I)       Q9NRJ3   P09gh4   CC chemokine CCL28   250.0021   1830   763.2866   948.0274   1.61E+00   2.87E+00   19   Int&gt; (A; I)       P05305   F17ab5   endothelin 1   866.4561   1810   403.431   1026.992   −1.10E+00   1.06E+00   19   Int&gt; (A; I)       P09341   A04ab6   GRO1 oncogene (melanoma gro             933.2938   4770   1006.711   2236.622   1.09E−01   2.35E+00   19   Int&gt; (A; I)       Q92730   O14ef4   GTP-binding protein   653.8575   2760   542.7528   1318.381   −2.69E−01   2.08E+00   19   Int&gt; (A; I)       Q9H5K0   L10gh5   hypothetical protein FLJ23360   151.2029   296   130.3196   192.6442   −2.14E−01   9.71E−01   19   Int&gt; (A; I)                                                 540.0362   1180   233.0055   650.8277   −1.21E+00   1.13E+00   19   Int&gt; (A; I)       P42701   A06ef7   Interleukin 12 receptor; beta 1   1227.347   22100   1333.521   8128.994   1.20E−01   4.17E+00   19   Int&gt; (A; I)       P09237   J15ef1   matrix metalloproteinase 7 (matri   9598.545   87300   19849.69   38905.32   1.05E+00   3.18E+00   19   Int&gt; (A; I)       P16860   O13ab8   natriurelic peptide precursor B   4340.214   12900   1260.906   6171.6   −1.78E+00   1.57E+00   19   Int&gt; (A; I)       P21359   L16ab7   neurofibromin 1 (neurofibromato             132.483   292   155.0822   193.3208   2.27E−01   1.14E+00   19   Int&gt; (A; I)       P02775   B07ef7   pro-platelet basic protein (Includ             33.98656   1400   265.2119   567.1992   2.96E+00   5.37E+00   19   Int&gt; (A; I)       Q9UDQ9   J22gh4   SBBI26 protein   121.5886   1080   238.8624   479.5908   9.74E−01   3.15E+00   19   Int&gt; (A; I)       O75635   P14cd3   serine (or cysteine) proteinase In   232.6336   3890   326.2581   1483.169   4.88E−01   4.08E+00   19   Int&gt; (A; I)       P02735   A11cd3   serum amyloid A1   496.9578   17400   957.6141   6295.724   9.46E−01   5.13E+00   19   Int&gt; (A; I)       O60635   F10cd5   tetraspan 1   321.8888   843   177.6479   447.5729   −8.58E−01   1.39E+00   19   Int&gt; (A; I)       P50591   C09cd4   tumor necrosis factor (ligand) su             536.7773   1550   476.2305   854.3061   −1.73E−01   1.53E+00   19   Int&gt; (A; I)       Q03169   I10ef7   tumor necrosis factor; alpha-indu   366.7502   1260   326.6536   650.583   −1.67E−01   1.78E+00   19   Int&gt; (A; I)       Q9C075   N11ef8   type I Intermediate filament cytok   848.9829   4200   401.4854   1818.182   −1.08E+00   2.31E+00   19   Int&gt; (A; I)       P02248   A01cd3   ubiquitin C   155.6735   892   62.04595   369.9913   −1.33E+00   2.52E+00   19   Int&gt; (A; I)       O95497   A15cd5   vanin 1   309.1556   1840   510.7208   887.0948   7.24E−01   2.57E+00   19   Int&gt; (A; I)       Q14202   B15cd5   zinc finger protein 261   199.6246   1040   247.9161   496.3668   3.13E−01   2.38E+00   19   Int&gt; (A; I)       P15514   M02ef7   amphiregulin (schwannoma-deri             103.1419   405   65.66067   191.2981   −6.52E−01   1.97E+00   18   Off A/I; On Int       Q9BZL9   I21gh8   B aggressive lymphoma gene   126.3951   211   84.56927   140.8098   −5.80E−01   7.42E−01   18   Off A/I; On Int       P30991   D14ef5   chemokine (C—X—C motif); recept             64.37115   260   120.2328   148.3131   9.01E−01   2.02E+00   18   Off A/I; On Int       P29400   H13ab3   collagen; type IV; alpha 5 (Alport   53.50943   374   141.1609   189.6904   1.40E+00   2.81E+00   18   Off A/I; On Int       Q9UK22   H22cd7   F-box only protein 2   87.59822   217   120.3781   141.6466   4.59E−01   1.31E+00   18   Off A/I; On Int       Q16769   O15cd8   glutaminyl-peptide cyclotransfera   89.90252   195   113.0683   132.7502   3.31E−01   1.12E+00   18   Off A/I; On Int       P02261   M06gh6   H2A histone family; member I   65.46028   263   126.664   151.868   9.52E−01   2.01E+00   18   Off A/I; On Int       P20769   D03ef1   immunoglobulin heavy constant              101.245   176   102.5687   126.7136   1.87E−02   8.00E−01   18   Off A/I; On Int       P52945   I12ab6   insulin promoter factor 1; homeo             74.60504   351   86.42558   170.7555   2.12E−01   2.24E+00   18   Off A/I; On Int       Q14496   F21cd6   interferon-Induced protein 44   99.27101   286   98.28057   161.3017   −1.45E−02   1.53E+00   18   Off A/I; On Int       P01583   F15ef7   interleukin 1; alpha   103.386   375   66.6314   181.5566   −6.34E−01   1.86E+00   18   Off A/I; On Int       P01584   F17ef7   interleukin 1; beta   116.7675   415   119.0156   216.8707   2.75E−02   1.83E+00   18   Off A/I; On Int       Q9GZM1   I20gh7   NDRG family member 4   102.1328   348   101.569   183.8736   −7.99E−03   1.77E+00   18   Off A/I; On Int       P25105   G15ef5   platelet-activating factor receptor   97.43121   358   80.47935   177.9689   −2.76E−01   1.87E+00   18   Off A/I; On Int       P58294   O14gh8   prokineticin 1 precursor   79.98286   241   137.5167   152.9437   7.82E−01   1.59E+00   18   Off A/I; On Int       P23471   A06ef6   protein tyrosine phosphatase; re             85.55935   346   93.65845   175.0253   1.30E−01   2.02E+00   18   Off A/I; On Int       O88386   D10ef3   RAB10; member RAS oncogene   123.2003   399   68.13944   196.7342   −8.54E−01   1.69E+00   18   Off A/I; On Int       P10826   I08gh6   retinoic acid receptor; beta   67.98871   241   120.9469   143.3844   8.31E−01   1.83E+00   18   Off A/I; On Int       O95786   I24ef3   RNA helicase   112.9366   241   89.32396   147.8829   −3.38E−01   1.10E+00   18   Off A/I; On Int       P02778   O10ef7   small Inducible cytokine subfamil             65.03395   418   86.09019   189.6022   4.05E−01   2.68E+00   18   Off A/I; On Int       P80162   F14cd1   small inducible cytokine subfamil             54.00821   311   129.2839   164.6594   1.26E+00   2.52E+00   18   Off A/I; On Int       P43005   N23ef5   solute carrier family 1 (neuronal/             99.30514   189   110.8119   133.1898   1.58E−01   9.32E−01   18   Off A/I; On Int       P01375   O09ef6   tumor necrosis factor (TNF supe             138.6153   386   75.13436   200.0804   −8.84E−01   1.48E+00   18   Off A/I; On Int       Q16890   G04cd2   tumor protein D52-like 1   103.5477   191   98.01862   130.885   −7.92E−02   8.84E−01   18   Off A/I; On Int       Q9H949   K11gh5   WW45 protein   111.8812   218   79.54574   136.5769   −4.92E−01   9.64E−01   18   Off A/I; On Int       Q9H4G4   O06gh5   17 kD fetal brain protein   88.61746   223   532.2979   281.2148   2.59E+00   1.33E+00   8   Off Acinar; Increasing Int/I       Q14040   B15ef1   collagen; type VI; alpha 1   38.27203   209   4724.413   1657.194   6.95E+00   2.45E+00   8   Off Acinar; Increasing Int/I       P12110   B17ef1   collagen; type VI; alpha 2   88.00282   164   3835.637   1362.487   5.45E+00   8.97E−01   8   Off Acinar; Increasing Int/I       P02751   K15ef1   fibronectin 1   4.441352   152   4171.603   1442.812   9.88E+00   5.10E+00   8   Off Acinar; Increasing Int/I       P14652   N23ab6   homeo box B2   62.71629   291   3571.974   1308.575   5.83E+00   2.21E+00   8   Off Acinar; Increasing Int/I       P08476   D15ef7   inhibin; beta A (activin A; activin   64.38161   318   854.6532   412.2794   3.73E+00   2.30E+00   8   Off Acinar; Increasing Int/I       P17936   D07ab6   Insulin-like growth factor binding   38.22268   349   1302.669   563.1937   5.09E+00   3.19E+00   8   Off Acinar; Increasing Int/I       Q9Y4K0   P18ab6   lysyl oxidase-like 2   75.91549   260   2525.644   953.7036   5.06E+00   1.77E+00   8   Off Acinar; Increasing Int/I       P03956   N05ef7   matrix metalloproteinase 1 (inter             106.2193   203   590.2622   299.8442   2.47E+00   9.53E−01   8   Off Acinar; Increasing Int/I       P39900   N15ef7   matrix metalloproteinase 12 (ma             18.2367   381   1219.953   539.7471   6.06E+00   4.39E+00   8   Off Acinar; Increasing Int/I       P55001   G09ab7   microfibrillar-associated protein 2   99.33548   526   3302.631   1309.293   5.06E+00   2.40E+00   8   Off Acinar; Increasing Int/I       Q9NYR0   O07gh7   SH3-domain kinase binding prot             34.69271   197   656.4675   296.0285   4.24E+00   2.50E+00   8   Off Acinar; Increasing Int/I       O43623   D06ef4   snail homolog 2 ( Drosophila )   96.88079   292   3028.508   1139.155   4.97E+00   1.59E+00   8   Off Acinar; Increasing Int/I       P09936   I13cd4   ubiquitin carboxyl-terminal ester             46.30052   219   1523.166   596.7714   4.98E+00   2.18E+00   8   Off Acinar; Increasing Int/I       Q02952   J11ab2   A kinase (PRKA) anchor protein   103.9756   364   229.1446   232.3779   1.14E+00   1.81E+00   4   Off Acinar; On Int = I       Q99541   I19ab2   adipose differentiation-related p             67.38509   182   146.1347   132.005   1.12E+00   1.44E+00   4   Off Acinar; On Int = I       P54284   N17ab3   calcium channel; voltage-depend   106.3248   227   254.9633   195.985   1.26E+00   1.09E+00   4   Off Acinar; On Int = I       Q13269   G14ab5   cAMP responsive element bindin   100.6639   193   217.7521   170.529   1.11E+00   9.40E−01   4   Off Acinar; On Int = I       Q9NPF2   M02ef4   chondroitin 4-sulfotransferase   133.8375   192   303.01   209.7612   1.18E+00   5.24E−01   4   Off Acinar; On Int = I       Q9H7A5   F12gh7   chromosome 20 open reading fra   98.71521   179   208.0134   161.8637   1.08E+00   8.58E−01   4   Off Acinar; On Int = I       Q9H9Q2   L23gh5   COP9 constitutive photomorpho             86.57682   115   184.3088   128.7341   1.09E+00   4.14E−01   4   Off Acinar; On Int = I       P42771   D17ef5   cyclin-dependent kinase Inhibitor   43.35217   471   355.7426   290.1928   3.04E+00   3.44E+00   4   Off Acinar; On Int = I       Q14650   J20ef4   cytoplasmic FMR1 interacting pr             132.5759   272   321.6348   242.2271   1.28E+00   1.04E+00   4   Off Acinar; On Int = I       Q96IK6   F14gh6   DKFZP434C245 protein   145.227   104   91.06477   113.265   −6.73E−01   −4.89E−01   4   Off Acinar; On Int = I       P12034   D05ef7   fibroblast growth factor 5   60.2377   259   317.6018   212.2747   2.40E+00   2.10E+00   4   Off Acinar; On Int = I       Q93079   M20gh6   H2B histone family; member J   144.6906   428   271.2983   281.3281   9.07E−01   1.56E+00   4   Off Acinar; On Int = I       Q9P016   A10ef8   HSPC144 protein   123.4601   348   399.4935   290.4476   1.69E+00   1.50E+00   4   Off Acinar; On Int = I       Q9HBI5   M09gh4   HT021   116.3605   276   309.5798   233.835   1.41E+00   1.24E+00   4   Off Acinar; On Int = I       Q9BY45   O24gh8   HTPAP protein   78.49388   109   177.2043   121.5622   1.17E+00   4.74E−01   4   Off Acinar; On Int = I       P08397   G18ab6   hydroxymethylbilane synthase   139.0857   188   260.8417   196.1361   9.07E−01   4.38E−01   4   Off Acinar; On Int = I       Q9BUV0   M06gh4   hypothetical protein dJ465N24.2.   68.40543   152   167.5592   129.3473   1.29E+00   1.15E+00   4   Off Acinar; On Int = I       Q9H9A2   N22gh6   hypothetical protein DKFZp762U   82.54725   110   169.5379   120.7311   1.04E+00   4.16E−01   4   Off Acinar; On Int = I       Q9NUV6   P09gh3   hypothetical protein FLJ11113   87.43713   178   136.6771   134.1021   6.44E−01   1.03E+00   4   Off Acinar; On Int = I       Q9NXF7   C20gh2   hypothetical protein FLJ20280   66.49705   143   170.7367   126.7851   1.36E+00   1.11E+00   4   Off Acinar; On Int = I       Q9H6V0   M05gh5   hypothetical protein FLJ21839   116.3704   258   323.3964   232.5844   1.47E+00   1.15E+00   4   Off Acinar; On Int = I       Q9BUW5   K21gh6   hypothetical protein MGC4707   80.31127   170   203.9516   151.3887   1.34E+00   1.08E+00   4   Off Acinar; On Int = I       Q9H765   I15gh6   hypothetical protein MGC5540   106.3949   220   206.6405   177.6046   9.58E−01   1.05E+00   4   Off Acinar; On Int = I       Q14157   N23gh1   KIAA0144 gene product   95.13957   147   147.7214   129.9305   6.35E−01   6.27E−01   4   Off Acinar; On Int = I       Q9Y2D8   A07ef8   KIAA0923 protein   84.1225   237   206.8269   176.1358   1.30E+00   1.50E+00   4   Off Acinar; On Int = I       Q9H6Z3   E24gh5   kinesin family member 13A   111.6382   206   238.8822   185.578   1.10E+00   8.85E−01   4   Off Acinar; On Int = I       Q99748   J24ab8   neurturin   123.7486   150   246.4754   173.2957   9.94E−01   2.74E−01   4   Off Acinar; On Int = I       Q9NVD7   D11gh3   parvin; alpha   82.67948   140   230.66   151.1753   1.48E+00   7.62E−01   4   Off Acinar; On Int = I       Q43175   H                                                                                                               4   Off Acinar; On Int = I       Q13636   K19cd7   RAB31; member RAS oncogene   76.36263   118   170.0352   121.5169   1.15E+00   6.30E−01   4   Off Acinar; On Int = I       Q9UIC2   L10ef2   RNB6   80.78879   171   194.395   148.7422   1.27E+00   1.08E+00   4   Off Acinar; On Int = I       Q9NVQ7   K12gh3   Sec61 alpha form 2   82.6036   143   162.0674   129.1434   9.72E−01   7.89E−01   4   Off Acinar; On Int = I       O75368   J08cd1   SH3 domain binding glutamic acl   92.82513   212   196.8753   167.1823   1.08E+00   1.19E+00   4   Off Acinar; On Int = I       O95863   N01cd2   snail homolog 1 ( Drosophila )   76.58448   134   157.9807   122.817   1.04E+00   8.06E−01   4   Off Acinar; On Int = I       Q9UL01   H01cd8   squamous cell carcinoma antige             86.70353   111   176.4557   124.5829   1.03E+00   3.51E−01   4   Off Acinar; On Int = I       Q16226   N05cd6   thioredoxin interacting protein   111.1384   454   529.2322   364.6675   2.25E+00   2.03E+00   4   Off Acinar; On Int = I       P07996   A11ef7   thrombospondin 1   79.00174   139   163.2593   127.0819   1.05E+00   8.15E−01   4   Off Acinar; On Int = I       Q99081   F10ef6   transcription factor 12 (HTF4; he   112.2294   181   256.0348   182.9347   1.19E+00   6.86E−01   4   Off Acinar; On Int = I       O95922   L06ef7   tubulin tyrosine ligase-like 1   73.12945   245   253.9213   190.8311   1.80E+00   1.75E+00   4   Off Acinar; On Int = I       P15036   H18ef6   v-ets erythroblastosis virus E26              149.9259   114   83.55955   115.8531   −8.43E−01   −3.94E−01   4   Off Acinar; On Int = I       O95337   D04ef8   weakly similar to glutathione per             69.55111   164   284.3593   172.7489   2.03E+00   1.24E+00   4   Off Acinar; On Int = I       Q9H1B5   M18gh5   xylosyltransferase II   81.87715   106   174.2539   120.5878   1.09E+00   3.68E−01   4   Off Acinar; On Int = I       P55263   K07ab2   adenosine kinase   891.6698   720   299.6337   637.198   −1.57E+00   −3.08E−01   15   On A/Int; Down I       P51648   A22ab2   aldehyde dehydrogenase 3 famil   1955.203   1390   507.3786   1284.046   −1.95E+00   −4.93E−01   15   On A/Int; Down I       P50995   I08ab2   annexin A11   4888.71   3870   1773.94   3511.843   −1.46E+00   −3.36E−01   15   On A/Int; Down I       P12429   I14ab2   annexin A3   9711.235   10800   1720.452   7424.351   −2.50E+00   1.59E−01   15   On A/Int; Down I       P05026   L22ab2   ATPase; Na+/K+ transporting; b             3965.733   5290   1976.367   3744.962   −1.00E+00   4.16E−01   15   On A/Int; Down I       P00751   M07ab3   B-factor; properdin   2984.309   2460   1178.473   2206.568   −1.34E+00   −2.81E−01   15   On A/Int; Down I       Q9HA23   E10gh6   calponin like transmembrane dor   480.5263   528   193.0456   400.5912   −1.32E+00   1.36E−01   15   On A/Int; Down I       Q16170   M17ab3   carcinoembryonic antigen-relate             984.7628   1230   212.7712   807.5766   −2.21E+00   3.15E−01   15   On A/Int; Down I       P25774   P07ab5   cathepsin S   857.9751   776   228.9093   620.9386   −1.91E+00   −1.45E−01   15   On A/Int; Down I       P21926   J13ef7   CD9 antigen (p24)   2011.966   3500   833.332   2115.74   −1.27E+00   8.00E−01   15   On A/Int; Down I       Q9H2A7   M19gh5   chemokine (C—X—C motif) ligand 1   650.7961   842   235.8205   576.1228   −1.46E+00   3.71E−01   15   On A/Int; Down I       O14493   G21ab4   claudin 4   1919.128   2480   799.5104   1732.749   −1.26E+00   3.70E−01   15   On A/Int; Down I       P12277   M06ab4   creatine kinase; brain   373.8119   617   193.0681   394.4895   −9.53E−01   7.22E−01   15   On A/Int; Down I       Q9NYS7   E20ef4   CS box-containing WD protein   596.6891   384   211.1821   397.3278   −1.50E+00   −6.35E−01   15   On A/Int; Down I       P53355   D09ab5   death-associated protein kinase   1325.243   1260   558.9756   1048.818   −1.25E+00   −7.03E−02   15   On A/Int; Down I       O15205   D17cd6   diubiqultin   7363.301   14700   2196.358   8102.423   −1.75E+00   1.00E+00   15   On A/Int; Down I       Q9UFZ2   C23ef8   DKFZP564K247 protein   1325.797   1060   313.5237   900.9109   −2.08E+00   −3.18E−01   15   On A/Int; Down I       P28562   M22ab5   dual specificity phosphatase 1   2077.188   1680   754.9876   1502.864   −1.46E+00   −3.09E−01   15   On A/Int; Down I       Q16690   B21ab4   dual specificity phosphatase 5   485.6475   305   155.0161   315.2743   −1.65E+00   −6.70E−01   15   On A/Int; Down I       Q9UJW0   H10ef1   dynactin 4 (p62)   778.5079   662   335.9831   592.1023   −1.21E+00   −2.34E−01   15   On A/Int; Down I           E13gh5   ectonucleotide pyrophosphatase   233.9728   378   183.3797   265.0097   −3.52E−01   6.91E−01   15   On A/Int; Down I       P00533   A06ef5   epidermal growth factor receptor   263.2516   334   182.4044   259.7582   −5.29E−01   3.42E−01   15   On A/Int; Down I       Q13113   J02cd5   epithelial protein up-regulated in   13324.19   15500   2641.961   10494.6   −2.33E+00   2.20E−01   15   On A/Int; Down I       P28161   M09ab6   glutathione S-transferase M2 (m             1020.341   690   217.4433   642.7437   −2.23E+00   −5.63E−01   15   On A/Int; Down I       Q03013   L06ab3   glutathione S-transferase M4   333.2767   465   210.8696   336.469   −6.60E−01   4.81E−01   15   On A/Int; Down I       P52594   A18ab7   HIV-1 Rev binding protein   439.4544   468   252.8058   386.6697   −7.98E−01   9.00E−02   15   On A/Int; Down I       Q9NWT9   D09gh2   hypothetical protein FLJ20607   1062.388   757   368.3558   729.2943   −1.53E+00   −4.89E−01   15   On A/Int; Down I       Q9BZR4   L12gh7   hypothetical protein HT036   748.0681   844   160.1449   584.0643   −2.22E+00   1.74E−01   15   On A/Int; Down I       Q9BW25   A19gh6   hypothetical protein MGC3101   315.4695   409   150.4768   291.8079   −1.07E+00   3.76E−01   15   On A/Int; Down I       P16144   I16ab6   integrin; beta 4   490.7243   672   157.31   440.0464   −1.64E+00   4.54E−01   15   On A/Int; Down I       P10145   O22ef7   interleukin 8   6902.736   13300   1783.339   7330.866   −1.95E+00   9.47E−01   15   On A/Int; Down I       Q05084   G10ab7   islet cell autoantigen 1 (69 kD)   600.5671   588   209.1329   465.8994   −1.52E+00   −3.05E−02   15   On A/Int; Down I       Q9Y484   E14cd7   JM5 protein   1335.218   2010   938.9827   1429.625   −5.08E−01   5.93E−01   15   On A/Int; Down I       P14923   M23ef6   junction plakoglobin   1969.949   2610   912.3081   1831.613   −1.11E+00   4.07E−01   15   On A/Int; Down I       P05783   N06ef6   keratin 8   17317.24   12500   2306.177   10707.79   −2.91E+00   −4.70E−01   15   On A/Int; Down I       P08727   L06ab6   keratin 19   4025.258   2800   631.8404   2484.93   −2.67E+00   −5.25E−01   15   On A/Int; Down I       P08729   N14ef6   keratin 7   11605.48   11100   1888.38   8203.912   −2.62E+00   −6.19E−02   15   On A/Int; Down I       P05787   N16ef6   keratin 8   11031.01   7880   1694.024   6867.677   −2.70E+00   −4.86E−01   15   On A/Int; Down I       O14782   H22ab6   kinesin family member 3C   366.3528   652   242.2822   420.177   −5.97E−01   8.31E−01   15   On A/Int; Down I       O00515   D05ab7   ladinin 1   3562.632   2040   824.2377   2140.683   −2.11E+00   −8.08E−01   15   On A/Int; Down I       P80188   D13ab7   lipocalin 2 (oncogene 24p3)   5234.435   9070   664.0466   4989.308   −2.98E+00   7.93E−01   15   On A/Int; Down I       Q9UQ53   G02ef3   mannosyl (alpha-1; 3-)-glycoprot             1485.546   931   398.5069   938.2331   −1.90E+00   −6.75E−01   15   On A/Int; Down I       P80294   D15gh6   metallothionein 1H   327.8489   366   208.8705   300.7815   −6.50E−01   1.57E−01   15   On A/Int; Down I       O75394   M10cd5   mitochondrial ribosomal protein              441.6574   646   213.7295   433.794   −1.05E+00   5.49E−01   15   On A/Int; Down I       Q9Y376   H18ef2   MO25 protein   860.3225   1410   550.0258   939.6431   −6.45E−01   7.11E−01   15   On A/Int; Down I       P15941   H22ab7   mucin 1; transmembrane   2330.649   1250   487.1995   1357.116   −2.26E+00   −8.95E−01   15   On A/Int; Down I       Q16301   H11cd4   myelin transcription factor 2   2433.02   2560   545.0513   1844.855   −2.16E+00   7.14E−02   15   On A/Int; Down I       Q99836   M07ab7   myeloid differentiation primary re   1088.39   1110   413.4864   871.4196   −1.40E+00   3.15E−02   15   On A/Int; Down I       P24001   H08cd4   natural killer cell transcript 4   49232.84   71300   13531.68   44684.13   −1.86E+00   5.34E−01   15   On A/Int; Down I       Q9C002   O12gh8   normal mucosa of esophagus sp             8605.554   17700   4423.686   10242.28   −9.60E−1   1.04E+00   15   On A/Int; Down I       P25963   A16ef1   nuclear factor of kappa light poly   938.908   1270   605.6116   937.0159   −6.33E−01   4.32E−01   15   On A/Int; Down I       P00491   L18ab7   nucleoside phosphorylase   820.4015   500   250.4586   523.7383   −1.71E+00   −7.13E−01   15   On A/Int; Down I       P49763   O20ef7   placental growth factor; vascular   5604.053   12600   1723.953   6646.258   −1.70E+00   1.17E+00   15   On A/Int; Down I       Q9Y342   A13ef2   plasmolipin   942.5595   983   300.2833   742.036   −1.65E+00   6.10E−02   15   On A/Int; Down I       P43490   H04cd5   pre-B-cell colony-enhancing fact             2261.72   1730   651.3251   1546.408   −1.80E+00   −3.90E−01   15   On A/Int; Down I       Q99988   B23ef7   prostate differentiation factor   1470.061   2930   681.8854   1694.813   −1.11E+00   9.96E−01   15   On A/Int; Down I       Q9UJY1   B05ef3   protein kinase H11   1836.927   2080   544.441   1485.828   −1.75E+00   1.77E−01   15   On A/Int; Down I       Q9H1C7   O10gh8   putative nuclear protein ORF1-F             11454.74   14800   3062.014   9771.26   −1.90E+00   3.69E−01   15   On A/Int; Down I       P51149   A21ef6   RAB7; member RAS oncogene f             3422.13   5250   2267.107   3646.784   −5.94E−01   6.18E−1   15   On A/Int; Down I       P51151   J22cd4   RAB9A; member RAS oncogene   1882.687   1580   721.6194   1393.904   −1.38E+00   −2.55E−01   15   On A/Int; Down I       P15153   C17ef6   ras-related C3 botulinum toxin s             383.0769   418   213.0301   338.0922   −8.47E−01   1.26E−01   15   On A/Int; Down I       P52566   I19ef1   Rho GDP dissociation inhibitor (             986.1501   788   352.0789   708.6827   −1.49E+00   −3.24E−01   15   On A/Int; Down I       P01011   I08ef7   serine (or cysteine) proteinase in   40450.89   43700   10172.44   31439.89   −1.99E+00   1.11E−01   15   On A/Int; Down I       P05120   P07ef7   serine (or cysteine) proteinase in   24922.82   38200   2879.818   21999.69   −3.11E+00   6.16E−01   15   On A/Int; Down I       O14508   M13ef6   STAT induced STAT inhibitor-2   1511.844   1490   420.453   1139.68   −1.85E+00   −2.42E−02   15   On A/Int; Down I       Q9Y6N5   G13gh4   sulfide dehydrogenase like (yeas   823.7665   871   284.0637   659.5107   −1.54E+00   7.99E−02   15   On A/Int; Down I       O00161   C23cd4   synaptosomal-associated protein   1077.833   1340   687.0432   1034.031   −6.50E−01   3.11E−01   15   On A/Int; Down I       P31431   F24cd1   syndecan 4 (amphiglycan; ryudo             2109.871   3080   887.6687   2026.067   −1.25E+00   5.46E−01   15   On A/Int; Down I       O15533   B16ef7   TAP binding protein (tapasin)   313.1585   424   162.3501   299.8834   −9.48E−01   4.38E−01   15   On A/Int; Down I       P17         87   F11ef5              1   4         5.8787   288   157.6175   317.0491   −1.65E+00   −7.35E−01   15   On A/Int; Down I       Q16149   B15cd1   transporter 1m; ATP-binding casse   862.1561   1100   480.8685   813.3307   −8.42E−01   3.47E−01   15   On A/Int; Down I       Q9Y2A9   C22ef3   UDP-GlcNac:betaGal beta-1; 3-N   774.5506   436   153.9485   454.8446   −2.33E+00   −8.29E−01   15   On A/Int; Down I       O60625   N10cd3   vesicle associated membrane p             2480.868   2680   584.39   1914.133   −2.09E+00   1.10E−01   15   On A/Int; Down I       P07948   A21ab7   v-yes-1 Yamaguchi sarcoma vira   512.646   443   170.1742   375.1466   −1.59E+00   −2.12E−01   15   On A/Int; Down I       Q9P2N4   M10gh4   a disintegrin-like and metalloprot   159.7274   227   72.96867   153.1495   −1.13E+00   5.06E−01   14   On A/Int; Off I       P47895   C04ab2   aldehyde dehydrogenase 1 famil   1247.008   2370   146.6644   1254.954   −3.09E+00   9.27E−01   14   On A/Int; Off I       P04233   G09ef1   CD74 antigen (invariant polypept   229.4566   174   86.99566   163.6002   −1.40E+00   −3.96E−01   14   On A/Int; Off I       Q9NZ31   L12gh4   chromosome 20 open reading fra             345.4771   375   137.4415   285.9642   −1.33E+00   1.18E−01   14   On A/Int; Off I       O96002   G07cd5   chromosome X open reading frar   401.521   375   130.7318   302.4558   −1.62E+00   −9.81E−02   14   On A/Int; Off I       O94907   J15gh6   dickkopf homolog 1 ( Xenopus  la             150.3215   200   84.53571   145.044   −8.30E−01   4.14E−01   14   On A/Int; Off I       Q92796   K06ef5   discs; large ( Drosophila ) homolo             161.9581   154   84.90819   133.5184   −9.32E−01   −7.56E−02   14   On A/Int; Off I       Q13115   O17ab4   dual specificity phosphatase 4   533.5415   730   146.312   469.8392   −1.87E+00   4.52E−01   14   On A/Int; Off I       P29317   F02ef5   EphA2   267.722   279   82.15254   209.5143   −1.70E+00   5.78E−02   14   On A/Int; Off I       P29323   D10ef5   EphB2   269.1598   232   74.35018   191.9946   −1.86E+00   −2.11E−01   14   On A/Int; Off I       Q9UKF9   H10cd7   ets homologous factor   603.0262   587   102.0333   430.6372   −2.56E+00   −3.92E−02   14   On A/Int; Off I       Q9NPD3   P22gh2   exosome component Rrp41   273.527   300   49.72784   207.9117   −2.46E+00   1.36E−01   14   On A/Int; Off I       O43524   G12ab4   forkhead box O3A   262.2734   169   102.6435   177.9385   −1.35E+00   −6.35E−01   14   On A/Int; Off I       P21217   M16ab3   fucosyltransferase 3 (galactoside   189.3354   257   60.24803   168.8097   −1.65E+00   4.40E−01   14   On A/Int; Off I       O75205   D24ef2   G protein-coupled receptor; famil   621.7284   382   90.93956   364.8596   −2.77E+00   −7.03E−01   14   On A/Int; Off I       O75712   A03ef1   gap junction protein; beta 3; 31 k             235.3139   402   145.5466   260.8655   −6.93E−01   7.72E−01   14   On A/Int; Off I       Q92908   D12ab4   GATA binding protein 6   293.117   199   93.59788   195.3976   −1.65E+00   −5.55E−01   14   On A/Int; Off I       O95210   P05cd4   genethonin 1   331.9855   241   112.69   228.6851   −1.56E+00   −4.60E−01   14   On A/Int; Off I       O95395   K21cd5   glucosaminyl (N-acetyl) transfera   297.4236   274   45.82301   205.5863   −2.70E+00   −1.21E−01   14   On A/Int; Off I       P48506   F22ab5   glutamate-cysteine ligase; cataly   299.1944   243   134.9982   225.879   −1.15E+00   −2.97E−01   14   On A/Int; Off I       Q9UI98   F08ef8   hqp0256 protein   357.587   336   106.803   266.8154   −1.74E+00   −8.96E−02   14   On A/Int; Off I       Q9H6D8   D18gh5   hypothetical protein FLJ22362   542.6184   595   127.4299   421.5312   −2.09E+00   1.32E−01   14   On A/Int; Off I       P05362   I02ab6   Intercellular adhesion molecule 1   411.0131   424   67.80016   301.0074   −2.60E+00   4.56E−02   14   On A/Int; Off I       Q07627   J20gh7   keratin associated protein 1.1   288.3566   303   40.28571   210.3957   −2.84E+00   6.93E−02   14   On A/Int; Off I       Q9BYQ7   D10gh8   keratin associated protein 4.10   493.4934   605   96.51137   398.2261   −2.35E+00   2.93E−01   14   On A/Int; Off I       O75071   F15gh1   KIAA0494 gene product   240.2512   167   91.77931   166.3595   −1.39E+00   −5.24E−01   14   On A/Int; Off I       Q9UPQ2   G22ef8   KIAA1100 protein   224.7248   349   135.6811   236.4102   −7.28E−01   6.34E−01   14   On A/Int; Off I       O43896   H10cd6   kinesin family member 1C   159.6982   170   73.44924   134.4385   −1.12E+00   9.16E−02   14   On A/Int; Off I       Q13887   L05ab5   Kruppel-like factor 5 (intestinal)   494.1259   376   97.43054   322.6178   −2.34E+00   −3.93E−01   14   On A/Int; Off I       O00312   D22cd3   MAP kinase-interacting serine/th             147.9629   150   86.60695   128.2701   −7.73E−01   2.20E−02   14   On A/Int; Off I       O15264   H07ab8   mitogen-activated protein kinase   213.7425   160   76.32069   150.0667   −1.49E+00   −4.17E−01   14   On A/Int; Off I       Q9UHA4   P10gh1   mitogen-activated protein kinase   268.8101   244   72.50042   195.0133   −1.89E+00   −1.41E−01   14   On A/Int; Off I       P21397   F23ef6   monoamine oxidase A   427.3495   480   30.42645   312.5207   −3.81E+00   1.67E−01   14   On A/Int; Off I       P55196   N07ab7   myeloid/lymphoid or mixed-linea             164.9238   168   78.62952   137.1449   −1.07E+00   2.56E−02   14   On A/Int; Off I       Q12965   I24ab7   myosin IE   212.4935   276   122.0015   203.3655   −8.01E−01   3.75E−01   14   On A/Int; Off I       Q9HBW1   O10gh7   NAG14 protein   417.9837   396   86.84398   300.2834   −2.27E+00   −7.79E−02   14   On A/Int; Off I       Q9H2W4   D20gh6   neural precursor cell expressed;   361.6431   483   75.41197   299.9778   −2.26E+00   3.56E−01   14   On A/Int; Off I       Q9NRR3   O06gh4   non-kinase CDc42 effector protei   194.8075   327   117.0936   213.1256   −7.34E−01   7.49E−01   14   On A/Int; Off I       P23511   M19ab8   nuclear transcription factor Y; al             239.2485   226   132.3351   199.2783   −8.54E−01   −8.06E−02   14   On A/Int; Off I       Q99650   D14cd4   oncostatin M receptor   337.1614   233   141.0848   237.114   −1.26E+00   −5.33E−01   14   On A/Int; Off I       P04085   O16ef7   platelet-derived growth factor alp             441.7554   463   124.4793   343.2015   −1.83E+01   6.89E−02   14   On A/Int; Off I       Q13048   N06cd2   pregnancy specific beta-1-glycop             149.7737   203   84.53571   145.8869   −8.25E−01   4.41E−01   14   On A/Int; Off I       P10586   E11ef6   protein lyrosine phosphatase; re             466.2876   405   136.6718   335.8682   −1.77E+00   −2.05E−01   14   On A/Int; Off I       O95200   N22ab8   retinoic acid receptor responder              437.2899   315   72.62859   275.0752   −2.59E+00   −4.72E−01   14   On A/Int; Off I       Q9NVX8   P17ef3   Rho GTPase activating protein 8   425.2848   479   109.2541   337.8544   −1.96E+00   1.72E−01   14   On A/Int; Off I       Q15418   N14ef5   ribosomal protein S6 kinase; 90 k   299.528   361   78.38666   246.2347   −1.93E+00   2.68E−01   14   On A/Int; Off I       Q15434   F10ab8   RNA binding motif; single strand             454.6438   328   145.2438   309.3377   −1.65E+00   −4.70E−01   14   On A/Int; Off I       Q15437   O10cd6   Sec23 homolog B ( S. cerevisiae )   281.2005   235   126.9582   214.4633   −1.15E+00   −2.58E−01   14   On A/Int; Off I       O60679   D15ef5   serum-inducible kinase   202.0368   194   62.20916   152.8498   −1.70E+00   −5.63E−02   14   On A/Int; Off I       Q12890   N06ef5   SFRS protein kinase 1   350.4057   278   113.0428   247.1823   −1.63E+00   −3.33E−01   14   On A/Int; Off I       Q12971   L03cd6   sialyitransferase   247.3141   329   96.91002   224.3379   −1.35E+00   4.11E−01   14   On A/Int; Off I       P78556   M02cd2   small inducible cytokine subfamil   308.0437   382   59.31325   249.7105   −2.38E+00   3.10E−01   14   On A/Int; Off I       O75751   F14ef4   solute carrier family 22 (extraneu   164.6419   238   66.83593   156.4431   −1.30E+00   5.31E−01   14   On A/Int; Off I       Q9UM01   D08cd4   solute carrier family 7 (cationic              201.657   260   55.89528   172.4611   −1.85E+00   3.66E−01   14   On A/Int; Off I       Q9Y5X1   D10ef2   sorting nexin 9   219.1839   240   108.9101   189.2981   −1.01E+00   1.30E−01   14   On A/Int; Off I       P08842   D19ab3   steroid sulfatase (microsomal); a   436.4255   414   136.2997   328.904   −1.68E+00   −7.62E−02   14   On A/Int; Off I       O43760   G09cd5   synaptogyrin 2   391.0545   238   118.1167   249.1866   −1.73E+00   −7.14E−01   14   On A/Int; Off I       O75674   N15cd5   target of myb1-like 1 (chicken)   276.5234   285   54.32353   205.2456   −2.35E+00   4.30E−02   14   On A/Int; Off I       P01135   K04ef7   transforming growth factor; alpha   215.9023   160   59.63082   145.3108   −1.86E+00   −4.29E−01   14   On A/Int; Off I       Q9NT70   K13gh3   transmembrane protein vezatin   365.9385   401   129.2607   298.7991   −1.50E+00   1.33E−01   14   On A/Int; Off I       O60656   G13gh3   UDP glycosyltransferase 1 family   546.3937   438   27.51254   337.3961   −4.31E+00   −3.18E−01   14   On A/Int; Off I       Q9NZ42   N18gh4   uncharacterized hematopoietic s             196.9377   213   115.2737   175.1842   −7.73E−01   1.15E−01   14   On A/Int; Off I       O76080   E14cd4   zinc finger protein 216   314.9706   211   74.56541   200.0768   −2.08E+00   −5.80E−01   14   On A/Int; Off I       Q13015   H11ab2   ALL1-fused gene from chromoso   329.6061   1730   1752.9   1272.138   2.41E+00   2.40E+00   6   On Acinar; Up Int = I       P04083   I06ab2   annexin A1   1114.486   8240   8292.245   5883.787   2.90E+00   2.89E+00   6   On Acinar; Up Int = I       O605962   B14ab2   Arg/Abi-interacting protein ArgBF   1576.114   3320   2017.836   2304.427   3.56E−01   1.07E+00   6   On Acinar; Up Int = I       Q07814   E04ef6   BCL2-associated X protein   430.8903   862   1101.457   797.9572   1.35E+00   1.00E+00   6   On Acinar; Up Int = I       Q14201   E17cd7   BTG family; member 3   197.8608   451   419.4378   355.9496   1.08E+00   1.19E+00   6   On Acinar; Up Int = I       Q9NR00   J21gh4   chromosome 8 open reading fra             2766.931   7310   3283.111   4453.955   2.47E−01   1.40E+00   6   On Acinar; Up Int = I       Q9BUW7   K19gh6   chromosome 9 open reading fra             228.4878   650   551.4272   476.5934   1.27E+00   1.51E+00   6   On Acinar; Up Int = I       O95401   N04cd4   cofactor required for Sp1 transcri   186.3494   395   588.6133   390.063   1.66E+00   1.08E+00   6   On Acinar; Up Int = I       Q00535   B09ef5   cyclin-dependent kinase 5   269.7495   476   432.1176   392.629   6.80E−01   8.19E−01   6   On Acinar; Up Int = I       P21741   E17ab7   midkine (neurite growth-promotin   2991.463   15400   9802.658   9388.855   1.71E+00   2.36E+00   6   On Acinar; Up Int = I       Q9Y291   J15ef2   mitochondrial ribosomal protein              177.4689   330   365.4484   290.8529   1.04E+00   8.93E−01   6   On Acinar; Up Int = I       O75376   E17cd6   nuclear receptor co-repressor 1   375.3879   1270   727.3836   791.9381   9.54E−01   1.76E+00   6   On Acinar; Up Int = I       P03973   N10cd1   secretory leukocyte protease inhi   592.855   2070   4153.51   2270.718   2.81E+00   1.80E+00   6   On Acinar; Up Int = I       O15427   F06cd4   solute carrier family 16 (monocar   228.58   753   785.8975   589.0175   1.78E+00   1.72E+00   6   On Acinar; Up Int = I       P16949   D11ab7   siathrnin 1/oncoprotein 18   728.2643   2630   1984.807   1781.654   1.45E+00   1.85E+00   6   On Acinar; Up Int = I       Q9NZ86   J08gh3   uncharacterized bone marrow p             311.3754   945   536.938   597.7198   7.86E−01   1.60E+00   6   On Acinar; Up Int = I       P50440   A09ab5   glycine amidinotransferase (L-ar             1737.906   395   261.2318   798.1958   −2.73E+00   −2.14E+00   20   Other       P29622   A06cd1   serine (or cysteine) proteinase In             461.3518   189   264.9574   304.9848   −8.00E−01   −1.29E+00   20   Other       O14646   C17ab4   chromodomain helicase DNA bin             867.7631   180   273.1703   440.3418   −1.67E+00   −2.27E+00   20   Other       P48307   I10cd4   tissue factor pathway Inhibitor 2   920.3007   366   277.6619   521.385   −1.73E+00   −1.33E+00   20   Other       Q15125   D08cd6   emopamil binding protein (sterol             897.4306   230   282.4317   470.0852   −1.67E+00   −1.96E+00   20   Other       P19387   B13ab8   polymerase (RNA) II (DNA direct             196.4282   155   282.8549   211.5128   5.26E−01   −3.39E−01   20   Other       Q9P0K7   H08gh6   retinoic acid induced 14   177.983   275   283.8007   245.4643   6.73E−01   6.26E−01   20   Other       P30086   E04ab8   prostalic binding protein   634.2686   462   300.6211   465.627   −1.08E+00   −4.57E−01   20   Other       Q13045   C06ab5   flightless I homolog ( Drosophila )   622.7072   501   306.0777   476.5407   −1.02E+00   −3.14E−01   20   Other       O95084   G10cd7   protease; serince; 23   1096.756   246   314.746   552.6166   −1.80E+00   −2.15E+00   20   Other       P49770   L11ef4   eukaryotic translation Initiation fa             731.6826   547   329.7361   536.2071   −1.15E+00   −4.19E−01   20   Other       Q13948   J02ef6   cut-like 1; CCAAT displacement              222.2758   349   330.5149   300.5112   5.72E−01   6.50E−01   20   Other       Q30201   H05ab3   hemochromatosis   205.1607   291   339.4607   278.446   7.26E−01   5.03E−01   20   Other       P52895   I16gh6   aido-keto reductase family 1; m             4001.572   263   339.7988   1534.634   −3.56E+00   −3.93E+00   20   Other       Q9Y5N1   M24cd7   histamine receptor H3   526.5133   203   341.1301   356.7517   −6.26E−01   −1.38E+00   20   Other       P43378   N23ab8   protein tyrosine phosphatase; no   1360.729   445   368.4734   724.8175   −1.88E+00   −1.61E+00   20   Other       P35414   O11ab2   angiotensin receptor-like 1   620.7039   406   395.8948   474.2345   −6.49E−01   −6.12E−01   20   Other       Q14802   K03cd1   FXYD domain-containing ion tra             2174.215   711   402.87   1096.127   −2.43E+00   −1.61E+00   20   Other       Q9Y266   F16cd6   nuclear distribution gene C hom             745.3985   447   408.3037   533.6949   −8.68E−01   −7.37E−01   20   Other       P30043   O21ab3   biliverdin reductase B (flavin red             877.6813   565   417.1383   620.0433   −1.07E+00   −6.35E−01   20   Other       Q9NP73   L06gh3   uncharacterized hematopoietic s             804.2103   446   421.5183   557.2055   −9.32E−01   −8.51E−01   20   Other       Q12972   D17ab8   protein phosphatase 1; regulator   251.1796   358   425.52   345.0523   7.61E−01   5.13E−01   20   Other       Q9Y288   N21ef2   PTD009 protein   738.5086   424   436.6114   532.9995   −7.58E−01   −8.01E−01   20   Other       Q02750   K02ef7   mitogen-activated protein kinase   810.206   508   441.4249   586.6635   −8.76E−01   −6.72E−01   20   Other       P42226   G23cd2   signal transducer and activator O   892.6025   516   450.4229   619.5568   −9.87E−01   −7.92E−01   20   Other       P31947   M07ef6   stratifin   2941.197   741   452.267   1378.205   −2.70E+00   −1.99E+00   20   Other       P46597   J12ab2   acetylserotonin O-methyltransfer.   2225.944   437   466.9229   1043.272   −2.25E+00   −2.35E+00   20   Other       O14745   J24cd4   solute carrier family 9 (sodium/h             1844.719   642   504.4269   997.106   −1.87E+00   −1.52E+00   20   Other       Q9NS67   D24gh1   G protein-coupled receptor 27   1464.475   381   595.0192   813.4043   −1.30E+00   −1.94E+00   20   Other       Q9UKL5   J07cd8   programmed cell death 6 interact   995.6375   886   605.9272   829.3129   −7.16E−01   −1.68E−01   20   Other       Q9UQL3   B11ef2   liver-specific bHLH-Zip transcript   825.7324   1150   606.7901   860.8974   −4.44E−01   4.78E−01   20   Other       Q9NZZ1   P18ef2   hypothetical protein HSPC138   397.5554   450   618.4035   488.5944   6.37E−01   1.78E−01   20   Other       Q9Y3Q3   H03cd7   integral type I protein   526.2023   355   631.4284   504.2124   2.63E−01   −5.68E−01   20   Other       Q9NSN3   C10gh4   similar to aspartate beta hydroxy   355.1305   273   667.4052   431.8528   9.10E−01   −3.79E−01   20   Other       Q9Y5Z0   B12cd7   beta-site APP-cleaving enzyme 2   1469.687   960   680.3343   1036.811   −1.11E+00   −6.14E−01   20   Other           C21gh7   H2B histone family; member B   511.589   855   733.4035   699.9713   5.20E−01   7.41E−01   20   Other       O14713   M11cd5   integrin cytoplasmic domain-ass             446.3806   746   737.9643   643.5596   7.25E−01   7.42E−01   20   Other       P46095   P11ab4   G protein-coupled receptor 6   2336.841   460   760.4217   1185.918   −1.62E+00   −2.34E+00   20   Other       Q98V10   K07gh6   hypothetical protein MGC3136   1761.627   653   779.7338   1064.815   −1.18E+00   −1.43E+00   20   Other       Q99653   O08cd7   calcium binding protein P22   1713.549   1430   793.2383   1313.03   −1.11E+00   −2.59E−01   20   Other       P41584   P16gh1   polymerase (RNA) II (DNA direct   560.1066   892   821.9856   758.0427   5.53E−01   6.71E−01   20   Other       P11940   E06ab8   poly(A) binding protein; cytoplas             1738.585   669   827.8343   1078.525   −1.07E+00   −1.38E+00   20   Other       Q00341   G21ab6   high density lipoprotein binding              545.5844   444   866.5328   618.5713   6.67E−01   −2.99E−01   20   Other       Q16795   K08ab7   NADH dehydrogenase (ubiquino             1582.872   1190   873.0478   1214.409   −8.58E−01   −4.15E−01   20   Other       Q13082   E05ab7   microtubule-associated protein 4   1217.396   472   873.8683   854.4272   −4.78E−01   −1.37E+00   20   Other       P36405   D16ab2   ADP-ribosytation factor-like 3   508.3031   547   939.7284   665.1099   8.87E−01   1.07E−01   20   Other       Q9NXH2   C04gh2   hypothetical protein FLJ20254   515.6731   467   959.9781   647.4269   8.97E−01   −1.44E−01   20   Other       Q9Y323   D21ef2   hypothetical protein HSPC177   838.9663   1630   976.2242   1148.545   2.19E−01   9.59E−01   20   Other       P48059   I12ab7   LIM and senescent cell antigen-             560.9674   918   1003.945   827.7691   6.40E−01   7.11E−01   20   Other       Q9P0M9   M02ef2   mitochondrial ribosomal protein              579.0083   936   1024.359   846.5801   8.23E−01   6.93E−01   20   Other       Q13813   E07cd2   spectrin; alpha; non-erythrocytic   2261.592   886   1070.984   1406.107   −1.08E+00   −1.35E+00   20   Other       Q9Y379   H07ef2   CGI-69 protein   2556.713   1900   1174.107   1877.939   −1.12E+00   −4.26E−01   20   Other       Q13247   O13gh1   splicing factor; arginine/serine-ri             718.1614   1210   1194.951   1041.827   7.35E−01   7.55E−01   20   Other       P14416   D03ef6   dopamine receptor D2   814.5351   745   1299.03   952.9439   6.73E−01   −1.28E−01   20   Other       Q06323   A15ef7   proteasome (prosome; macropal             1491.803   2350   1386.719   1742.377   −1.05E−01   6.55E−01   20   Other       Q9NR31   H17gh4   SAR1 protein   752.6343   886   1386.849   1008.646   8.82E−01   2.36E−01   20   Other       P05451   C07cd3   regenerating islet-derived 1 alpha   75644.12   1690   1394.425   26243.72   −5.76E+00   −5.48E+00   20   Other       P04075   C12ab2   aldolase A; fructose-bisphosphat   4534.199   1590   1470.967   2532.66   −1.62E+00   −1.51E+00   20   Other       Q15904   A19ab3   ATPase; H+ transporting; lysoso             833.0193   1380   1471.799   1228.765   8.21E−01   7.30E−01   20   Other       P15559   G24ef7   NAD(P)H dehydrogenase; quino             537.0892   303   1486.45   775.5735   1.47E+00   −8.25E−01   20   Other       O00303   L20cd3   eukaryotic translation initiation fa             1234.805   636   1556.448   1145.377   3.23E−01   −9.68E−01   20   Other       P56705   M01gh7   wingless-type MMTV integration   3589.752   1590   1635.805   2271.364   −1.13E+00   −1.18E+00   20   Other       P39210   I04ef7   MpV17 transgene; murine homo             990.336   894   1723.06   1202.587   7.99E−01   −1.47E−01   20   Other       Q9UKL9   N03ef4   aldo-keto reductase family 1; m             16311.31   2840   1896.102   7016.796   −3.10E+00   −2.52E+00   20   Other       O43516   E12cd3   Wiskott-Aldrich syndrome protein   1162.511   1190   1976.246   1444.29   7.68E−01   3.51E−02   20   Other       Q9Y470   D01ef7   stem cell growth factor; lymphoc             1346.693   1110   2049.542   1503.556   6.06E−01   −2.73E−01   20   Other       P29312   H12cd4   lyrosine 3-monooxygenase/tryopt             5187.766   4710   2331.854   4076.247   −1.15E+00   −1.40E−01   20   Other       Q9Y5R8   P24gh4   MUM2 protein   1596.032   1750   2568.113   1971.095   6.86E−01   1.32E−01   20   Other       P17676   D01ab5   CCAAT/enhancer binding protein   6064.068   2880   2723.688   3890.676   −1.15E+00   −1.07E+00   20   Other       O95362   F11gh6   differentially expressed in hemat             10407.52   2680   2912.158   5333.102   −1.84E+00   −1.96E+00   20   Other       O60417   C11gh7   S100 calcium binding protein A1             6955.642   5690   3097.579   5248.939   −1.17E+00   −2.89E−01   20   Other       P19623   E17cd2   spermidine synthase   1644.266   1020   3417.978   2027.643   1.06E+00   −6.88E−01   20   Other       Q9P039   P02ef7   FXYD domain-containing ion tra             2410.08   2120   4486.029   3004.627   8.96E−01   −1.87E−01   20   Other       Q9BUF5   F05gh8   tubulin beta-5   2252.623   1580   4730.755   2855.744   1.07E+00   −5.08E−01   20   Other       P00995   C23cd2   serine protease inhibitor; Kazal              67989.21   11300   5416.175   28226.58   −3.65E+00   −2.59E+00   20   Other       P11142   E22ef7   heat shock 70 kD protein 8   11154.99   7640   5433.843   8144.601   −1.04E+00   −5.08E−01   20   Other       P10620   E16ef7   microsomal glutathione S-transfe   6706.736   2430   5571.411   4901.595   −2.68E−01   −1.47E+00   20   Other       Q13347   N02cd3   eukaryotic translation initiation fa   19633.03   5210   5660.757   10168.91   −1.79E+00   −1.91E+00   20   Other       P15880   B16cd1   ribosomal protein S2   4356.01   2060   5964.993   4127.437   4.54E−01   −1.08E+00   20   Other       Q9HCU0   E24gh4   tumor endothelial marker 1 prec             3139.145   2600   7148.075   4295.784   1.19E+00   −2.72E−01   20   Other       Q04941   O16ab8   proteolipid protein 2 (colonic epit   17951.73   11800   8567.736   12775.93   −1.07E+00   −6.04E−01   20   Other       Q9UPI1   M14cd2   small nuclear ribonucleoprotein              4625.515   8280   8998.787   7300.387   9.60E−01   8.39E−01   20   Other       P13987   B18ef7   CD59 antigen p18-20 (antigen id   17383.17   19200   10453.43   15673.38   −7.34E−01   1.42E−01   20   Other       Q9UI09   L02gh4   13 kDa differentiation-associated   1754.698   1990   2889.148   2210.198   7.19E−01   1.79E−01   3   Unchanged High       Q9Y6H1   E23ef2   16.7 Kd protein   5687.333   4050   5837.94   5191.628   3.77E−02   −4.90E−01   3   Unchanged High       Q9P0U1   C07gh3   6.2 kd protein   2323.402   1990   3847.586   2721.439   7.28E−01   −2.21E−01   3   Unchanged High       P80095   N10ab7   6-pyruvoyl-tetrahydropterin syn             3223.922   2620   1569.69   2241.592   −1.04E+00   −2.99E−01   3   Unchanged High       Q92747   F04ab2   actin related protein ⅔ complex   4894.401   3990   3030.018   3972.89   −6.92E−01   −2.93E−01   3   Unchanged High       O15144   F08ab2   actin related protein ⅔ complex   13976.76   21400   17206.31   17538.09   3.00E−01   6.17E−01   3   Unchanged High       O15145   F10ab2   actin related protein ⅔ complex   3065.881   3190   1793.813   2683.638   −7.73E−01   5.78E−02   3   Unchanged High       P02570   A01cd7   actin; beta   66304.81   45400   38777.92   50171.41   −7.74E−01   −5.45E−01   3   Unchanged High       P02570   H12cd7   actin; beta   84949.74   42400   44598.66   50643.44   −5.42E−01   −6.16E−01   3   Unchanged High       P02570   P12cd7   actin; beta   21347.36   12200   15408.61   16331.85   −4.70E−01   −8.03E−01   3   Unchanged High       P02571   A06ab6   actin; gamma 1   69165.16   59100   65677.15   64643.45   −7.47E−02   −2.27E−01   3   Unchanged High       P12814   E23ab2   actinin; alpha 1   2400.607   2160   2638.011   2400.844   1.36E−01   −1.50E−01   3   Unchanged High       O43707   G05ab2   actinin; alpha 4   6999.138   3810   3499.234   4769.196   −1.00E+00   −8.78E−01   3   Unchanged High       P53999   C05cd7   activated RNA polymerase II tran   4478.986   4320   6009.318   4936.98   4.24E−01   −5.13E−02   3   Unchanged High       P18848   I03ef5   activating transcription factor 4 (t   7160.888   5420   7668.286   6749.873   9.88E−02   −4.02E−01   3   Unchanged High       P53680   A07ef1   adaptor-related protein complex:   2255.235   2530   4102.633   2963.423   8.63E−01   1.67E−01   3   Unchanged High       P29274   A18ef5   adenosine A2a receptor   1990.124   2960   2004.596   2318.367   1.05E−02   5.73E−01   3   Unchanged High       P54819   A04ab2   adenylate kinase 2   2997.607   2520   2851.739   2788.3   −7.20E−02   −2.53E−01   3   Unchanged High       Q01518   O18cd6   adenylyl cyclase-associated prot   6946.788   11000   7171.205   8362.375   4.59E−02   6.59E−01   3   Unchanged High       P32889   C03ef6   ADP-ribosylation factor 1   6040.796   7220   7907.02   7058.851   3.88E−01   2.58E−01   3   Unchanged High       P18085   P21ab2   ADP-ribosylation factor 4   4777.904   8880   8342.165   7331.81   8.04E−01   8.93E−01   3   Unchanged High       P26437   B02ab2   ADP-ribosylation factor 5   3739.477   4430   3984.845   4052.262   9.17E−02   2.45E−01   3   Unchanged High       Q9BZX4   L08gh6   AKAP-binding sperm protein rop             2345.455   2780   2500.118   2541.066   9.21E−02   2.44E−01   3   Unchanged High       P11768   K01ab2   alchocol dehydrogenase 5 (class              2220.156   1990   2854.318   2354.247   3.62E−01   −1.59E−01   3   Unchanged High       P05067   N03ef6   amyloid beta (A4) precursor prot             2846.85   4180   3918.595   3649.558   4.61E−01   5.55E−01   3   Unchanged High       Q06481   K22ab2   amyloid beta (A4) precursor-like   2117.652   3230   2290.191   2546.598   1.13E−01   6.10E−01   3   Unchanged High       P07355   I12ab2   annexin A2   74767.39   112000   97217.17   94734.13   3.79E−01   5.86E−01   3   Unchanged High       P08758   I18ab2   annexin A5   4487.905   4270   7134.202   5295.976   6.69E−01   −7.32E−02   3   Unchanged High       P55064   O08ab2   aquaporin 5   10851.57   14200   11650.24   12248.87   1.02E−01   3.93E−01   3   Unchanged High       Q13520   O10ab2   aquaporin 6; kidney specific   2404.748   2350   2457.278   2404.397   3.12E−02   −3.25E−02   3   Unchanged High       P32391   D19ab2   ARP3 actin-related protein 3 hon   4291.823   4280   3941.05   4171.013   −1.23E−01   −3.92E−03   3   Unchanged High       O43776   E18ab7   asparaginyl-tRNA synthetase   2570.968   3010   2854.989   2811.634   1.51E−01   2.27E−01   3   Unchanged High       P24539   N22ab2   ATP synthase; H+ transporting; r   2908.697   3800   3228.203   3312.717   1.50E−01   3.86E−01   3   Unchanged High       P48201   P04ab2   ATP synthase; H+ transporting; r   5694.182   4370   4857.955   4974.135   −2.29E−01   −3.82E−01   3   Unchanged High       P05496   N24ab2   ATP synthase; H+ transporting; r   2176.378   1760   2400.575   2112.628   1.41E−01   −3.06E−01   3   Unchanged High       Q06055   P02ab2   ATP synthase; H+ transporting; r   5784.579   3530   7732.552   5682.609   4.19E−01   −7.12E−01   3   Unchanged High       O75947   P14ab2   ATP synthase; H+ transporting; r   2668.028   2520   1881.974   2355.858   −5.04E−01   −8.37E−02   3   Unchanged High       P56385   P06ab2   ATP synthase; H+ transporting; r   2682.798   2090   2616.726   2462.524   −3.60E−02   −3.62E−01   3   Unchanged High       P56134   P10ab2   ATP synthase; H+ transporting; r   11587.91   17200   14181.18   14327.12   2.91E−01   5.71E−01   3   Unchanged High       P18859   P08ab2   ATP synthase; H+ transporting; r   3879.939   4840   5176.585   4633.559   4.16E−01   3.20E−01   3   Unchanged High       O75964   P16ab2   ATP synthase; H+ transporting; r   2021.591   2630   2009.026   2219.11   −8.99E−03   3.78E−01   3   Unchanged High       P25705   N14ab2   ATP synthase; H+ transporting; r   3657.512   2410   2967.207   3009.915   −3.02E−01   −6.05E−01   3   Unchanged High       P06578   N16ab2   ATP synthase; H+ transporting; r   4072.978   3280   2557.962   3305.047   −6.71E−01   −3.11E−01   3   Unchanged High       P36542   N18ab2   ATP synthase; H+ transporting; r   2479.5   2030   2436.284   2313.989   −2.54E−02   −2.91E−01   3   Unchanged High       P48047   P18ab2   ATP synthase; H+ transporting; r   4222.314   4100   3541.047   3955.838   −2.54E−01   −4.09E−02   3   Unchanged High       Q01814   P01ef5   ATPase; Ca++ transporting; plas   3157.447   3180   3242.707   3193.535   3.84E−02   1.05E−02   3   Unchanged High       Q99437   A11ab3   ATPase; H+ transporting; lysoso             2495.618   3870   2087.291   2817.803   −2.58E−01   6.33E−01   3   Unchanged High       P36543   A09ab3   ATPase; H+ transporting; lysoso             1854.198   2920   1659.749   2145.908   −1.60E−01   6.57E−01   3   Unchanged High       O75348   A15ab3   ATPase; H+ transporting; lysoso             2734.484   5660   2721.878   3704.42   −6.67E−03   1.05E+00   3   Unchanged High       Q16864   A21ab3   ATPase; H+ transporting; lysoso             6452.29   15900   7960.234   10101.59   3.03E−01   1.30E+00   3   Unchanged High       P27449   A05ab3   ATPase; H+ transporting; lysoso             17134.14   24300   13120.57   18185.04   −3.85E−01   5.04E−01   3   Unchanged High       O00244   L14ab2   ATX1 antioxidant protein 1 homo   2833.957   3500   3977.547   3435.675   4.89E−01   3.03E−01   3   Unchanged High       O14503   M18ab3   basic helix-loop-helix domain cor   4978.916   4280   3254.631   4169.761   −6.13E−01   −2.20E−01   3   Unchanged High       O60238   L11ab5   BCL2/adenovirus E1B 19 kD inte             1473.428   2420   3224.141   2371.407   1.13E+00   7.14E−01   3   Unchanged High       P30536   L21ab3   benzodiazapine receptor (periph             1997.929   2880   2326.211   2405.625   2.19E−01   5.34E−01   3   Unchanged High       P01884   C23ab3   beta-2-microglobulin   64872   105000   36055.95   68478.91   −8.47E−01   6.88E−01   3   Unchanged High       P22004   I13ab5   bone morphogenetic protein 6   5036.985   4710   3780.005   4509.317   −4.14E−01   −9.65E−02   3   Unchanged High       O95415   B02ef3   brain protein          3   7498.734   11200   5348.84   8032.295   −4.87E−01   5.85E−01   3   Unchanged High       O75531   K11ab3   Breakpoint cluster region protein   2541.789   2740   2924.826   2736.992   2.03E−01   1.11E−01   3   Unchanged High       P02593   A10ab6   calmodulin 2 (phospharylase kin             1573.77   4130   4742.485   3482.215   1.59E+00   1.39E+00   3   Unchanged High       P07384   O24ef1   calpain 1; (mu/l) large subunit   3429.132   3420   2390.011   3078.324   −5.21E−01   −5.61E−03   3   Unchanged High       P27797   P05ab5   calreticulin   10259.42   9700   15437.35   11797.33   5.89E−01   −8.16E−02   3   Unchanged High           N06gh8   CaM-KII inhibitory protein   20298.71   28200   21760.79   23425.99   1.00E−01   4.75E−01   3   Unchanged High       P47756   N14ab4   capping protein (actin filament) n   4348.079   4450   5015.377   4604.9   2.06E−01   3.38E−02   3   Unchanged High       P15086   H13ab5   carboxypeptidase B1 (tissue)   9766.062   27.1   26.97129   3273.378   −8.50E+00   −8.49E+00   3   Unchanged High       P52952   D22ab5   cardiac-specific homeo box   2859.197   1740   2282.546   2292.94   −3.25E−01   −7.19E−01   3   Unchanged High       P13862   M21ef1   casein kinase 2; beta polypeptid             3674.921   3840   3873.228   3795.282   7.58E−02   6.25E−02   3   Unchanged High       O14675   I02ef6   CASP8 and FADD-like apoptosis   2622.586   2500   1151.661   2092.229   −1.19E+00   −6.77E−02   3   Unchanged High       P35221   C17ef7   catenin (cadherin-associated pro   3813.516   4230   3300.738   3782.772   −2.08E−01   1.51E−01   3   Unchanged High       P07858   E01ab5   cathepsin B   2480.797   3860   4485.422   3607.853   8.54E−01   6.37E−01   3   Unchanged High       P48509   K16ab4   CD151 antigen   7267.56   13700   8768.731   9901.71   2.71E−01   9.11E−01   3   Unchanged High       P25063   G22cd8   CD24 antigen (small cell lung ca             21319.27   18200   8278.973   15932.79   −1.36E+00   −2.28E−01   3   Unchanged High       P16070   O21ef1   CD44 antigen (homing function a   16178.96   9640   5778.642   10533.43   −1.49E+00   −7.47E−01   3   Unchanged High       P08962   O18ab4   CD63 antigen (melanoma 1 an             9354.914   11600   10016.29   10307.1   9.86E−02   3.04E−01   3   Unchanged High       O14519   K04ef5   CDK2-associated protein 1   4231.191   4180   4763.013   4389.995   1.71E−01   −1.90E−02   3   Unchanged High       P25763   A12ab6   cell division cycle 42 (GTP bindi             4588.819   2840   2852.186   3426.736   −6.86E−01   −6.93E−01   3   Unchanged High       P49368   N17cd2   chaperonin containing TCP1; su             2356.627   2880   2222.361   2484.939   −8.46E−02   2.87E−01   3   Unchanged High       P48643   H10ef4   chaperonin containing TCP1; su             2238.933   2330   1561.625   2042.12   −5.20E−01   5.49E−02   3   Unchanged High       O00299   M19ab6   chloride intracellular channel 1   6811.55   7240   5727.121   6591.299   −2.50E−01   8.71E−02   3   Unchanged High       Q9Y2Q7   N02cd8   chromosome 11 open reading fr             4087.361   3800   5946.259   4610.942   5.41E−01   −1.05E−01   3   Unchanged High       P09496   F15ab5   clathrin; light polypeptide (Lca)   5758.632   9260   5849.641   6957.341   2.26E−02   6.86E−01   3   Unchanged High       O95832   L04gh1   claudin 1   3046.376   2450   918.0838   2138.383   −1.73E+00   −3.14E−01   3   Unchanged High       O95471   A13ef1   claudin 7   2888.819   3350   1520.977   2587.177   −9.25E−01   2.14E−01   3   Unchanged High       Q9UII4   B14ef1   cyclin-E binding protein 1   26180.8   29800   39655.02   31877.4   5.99E−01   1.87E−01   3   Unchanged High       P04080   G16ab3   cystatin B (stefin B)   4312.168   5420   2370.13   4034.272   −8.63E−01   3.30E−01   3   Unchanged High       P21291   J01ab5   cysteine and glycine-rich protein   2478.366   1710   2135.86   2109.096   −2.15E−01   −5.33E−01   3   Unchanged High       O00622   J15ef7   cysteine-rich; angiogenic inducer   2070.203   1620   2978.542   2224.339   5.25E−01   −3.50E−01   3   Unchanged High       P13073   L19ab5   cytochrome c oxidase subunit IV   6219.628   8550   6571.848   7115.048   7.95E−02   4.60E−01   3   Unchanged High       P12074   K13gh1   cytochrome c oxidase subunit VI             3253.24   5800   4244.557   4434.13   3.84E−01   8.35E−01   3   Unchanged High       Q02221   E17ab6   cytochrome c oxidase subunit VI             2968.24   2820   4604.241   3464.904   6.33E−01   −7.28E−02   3   Unchanged High       P14854   A20ab6   cytochrome c oxidase subunit VII   1991.91   2660   2380.795   2344.331   2.57E−01   4.17E−01   3   Unchanged High       P09669   E12ab6   cytochrome c oxidase subunit VI             2580.598   2090   1927.002   2197.56   −4.21E−01   −3.08E−01   3   Unchanged High       P14406   G02ab5   cytochrome c oxidase subunit VII   4846.713   4500   4245.478   4530.346   −1.91E−01   −1.07E−01   3   Unchanged High       O14548   G23cd5   cytochrome c oxidase subunit VII   2182.954   2450   3040.586   2556.481   4.78E−01   1.64E−01   3   Unchanged High       P24311   K17ab5   cytochrome c oxidase subunit VII   3224.558   5150   3601.752   4057.995   2.38E−01   6.75E−01   3   Unchanged High       P15954   P04ab5   cytochrome c oxidase subunit VII   12335.74   12200   9883.688   11482.48   −3.20E−01   −1.27E−02   3   Unchanged High       P10176   B10ab5   cytochrome c oxidase subunit VII   3019.162   1900   3329.281   2750.974   1.41E−01   −8.65E−01   3   Unchanged High       O43293   K19ab4   death-associated protein kinase   2535.403   1850   2088.808   2157.783   −2.80E−01   −4.55E−01   3   Unchanged High       P46966   G14ef6   defender against cell death 1   7921.682   11200   9546.896   9563.241   2.69E−01   5.02E−01   3   Unchanged High       Q09753   G01ab6   defensin; beta 1   4071.982   7630   2153.638   4619.611   −9.19E−01   9.07E−01   3   Unchanged High       P18282   F23ab2   destrin (actin depolymerizing fac             7729.126   7570   6083.408   7126.01   −3.45E−01   −3.09E−02   3   Unchanged High       P07108   H04gh1   diazepam binding inhibitor (GAB,   2541.011   1730   2995.768   2422.578   2.38E−01   −5.54E−01   3   Unchanged High       P31689   D18ab7   DnaJ (Hsp40) homolog; subfamil   2491.051   2930   1789.662   2402.398   −4.77E−01   2.32E−01   3   Unchanged High       Q9Y5T4   I10cd8   DNAJ domain-containing   2324.933   2520   2397.896   2414.457   4.46E−02   1.17E−01   3   Unchanged High       Q9Y463   G15cd5   dual-specificity tyrosine-(Y)-phos   8211.965   6870   5987.39   7023.599   −4.56E−01   −2.57E−01   3   Unchanged High       Q9NP97   C02ef8   dynein light chain 2A   4080.949   4160   5365.928   4534.283   3.95E−01   2.63E−02   3   Unchanged High       Q15701   L08cd3   dynein; cytoplasmic; light polype             4492.679   5800   4332.161   4875.685   −5.25E−02   3.69E−01   3   Unchanged High       P78545   O16ab4   E74-like factor 3 (ets domain tra             3781.196   2780   1455.944   2673.744   −1.38E+00   −4.42E−01   3   Unchanged High       O60869   A03cd4   endothelial differentiation-related   5515.692   5680   4090.527   5094.856   −4.31E−01   4.19E−02   3   Unchanged High       Q14259   L06ab4   enhancer of rudimentary homolo             3593.608   3950   5175.131   4241.036   5.26E−01   1.38E−01   3   Unchanged High       P06733   C16ab4   enolase 1; (alpha)   12539.97   7460   9955.024   9983.774   −3.33E−01   −7.50E−01   3   Unchanged High       P22712   D11gh6   enolase 1; (alpha)   6900.857   4290   5016.695   5403.444   −4.60E−01   −6.85E−01   3   Unchanged High       P04720   O07ab6   eukaryotic translation elongation   36222.34   23200   23485.94   27648.74   −6.25E−01   −6.40E−01   3   Unchanged High       P26641   A10ab4   eukaryotic translation elongation   6863.565   6540   11607.61   8337.901   7.58E−01   −6.91E−02   3   Unchanged High       P13639   I15ab5   eukaryotic translation elongation   4023.855   2310   3360.073   3231.325   −2.60E−01   −8.01E−01   3   Unchanged High       O15372   L24cd3   eukaryotic translation initiation fa             2870.027   1930   2391.869   2398.394   −2.63E−01   −5.70E−01   3   Unchanged High       O75821   L22cd3   eukaryotic translation initiation fa             3009.075   2670   3333.728   3005.577   1.48E−01   −1.70E−01   3   Unchanged High       Q64252   L11ab6   eukaryotic translation initiation fa             2755.438   1540   2127.874   2141.68   −3.73E−01   −8.38E−01   3   Unchanged High       O15371   L18cd3   eukaryotic translation initiation fa             4273.919   4030   3558.848   3954.373   −2.64E−01   −8.46E−02   3   Unchanged High       P04765   A22ab4   eukaryotic translation initiation fa             7716.222   7170   6363.169   7083.99   −2.78E−01   −1.05E−01   3   Unchanged High       Q14240   H13ab4   eukaryotic translation initiation fa             2091.816   2190   2519.322   2267.015   2.68E−01   6.61E−02   3   Unchanged High       P10159   A18ab5   eukaryotic translation initiation fa             9023.244   5240   5651.752   6638.65   −6.75E−01   −7.84E−01   3   Unchanged High       Q9NQT4   H05gh4   exosome component Rrp46   2098.514   2590   2304.48   2331.056   1.35E−01   3.04E−01   3   Unchanged High       P02794   C12ab6   ferritin; heavy polypeptide 1   35912.81   48700   42075.22   42243.59   2.28E−01   4.41E−01   3   Unchanged High       P02792   M10ab3   ferritin; light polypeptide   44225.86   29600   17849.2   30568.13   −1.31E+00   −5.78E−01   3   Unchanged High       Q05472   B02ab4   Finkel-Biskis-Reilly murine sarco   10322.94   10400   9704.642   10145.46   −8.91E−02   1.19E−02   3   Unchanged High       P20071   F08ab3   FK506 binding protein 1A (12 kD)   2741.389   1870   1414.969   2009.291   −9.54E−01   −5.51E−01   3   Unchanged High       P50395   J02ab4   GDP dissociation inhibitor 2   2287.713   1580   2291.27   2051.41   2.24E−03   −5.38E−01   3   Unchanged High       P48507   E12ab5   glutamate-cysteine ligase; modi             154.1773   76.2   5937.375   2055.914   5.27E+00   −1.02E+00   3   Unchanged High       P36969   D14ab5   glutathione peroxidase 4 (phosp             3397.2   4860   3108.036   3787.13   −1.28E−01   5.15E−01   3   Unchanged High       P09211   L10ab3   glutathione S-transferase pi   6392.334   8670   4067.789   6378.198   −6.52E−01   4.40E−01   3   Unchanged High       P04406   A01cd8   glyceraldehyde-3-phosphate deh             28809.37   38300   44655.67   37260.67   6.32E−01   4.11E−01   3   Unchanged High       P04406   H12cd8   glyceraldehyde-3-phosphate deh             37562.25   60200   57135.41   51621.55   6.05E−01   6.80E−01   3   Unchanged High       P04406   P12cd8   glyceraldehyde-3-phosphate deh             12053.5   14900   19061.62   15342.7   6.61E−01   3.07E−01   3   Unchanged High       P43304   H01ab3   glycerol-3-phosphate dehydroge             3450.634   2340   3276.264   3023.392   −7.48E−02   −5.58E−01   3   Unchanged High       P41250   F02ef7   glycyl-tRNA synthetase   4333.439   3630   6248.604   4736.632   5.28E−01   −2.56E−01   3   Unchanged High       P04895   K17ef5   GNAS complex locus   7755.858   9290   9107.558   8718.93   2.32E−01   2.61E−01   3   Unchanged High       P24522   B03ef6   growth arrest and DNA-damage-             2792.429   6130   3396.736   4105.138   2.83E−01   1.13E+00   3   Unchanged High       Q92847   M24ab5   growth hormone secretagogue re             2827.902   2100   2597.123   2508.414   −1.23E−01   −4.29E−01   3   Unchanged High       P04901   B01ef1   guanine nucleotide binding prote             5734.337   7610   5853.112   6398.85   2.96E−02   4.08E−01   3   Unchanged High       P25388   E20cd6   guanine nucleotide binding prote             22430.28   15300   19055.7   18939.85   −2.35E−01   −5.49E−01   3   Unchanged High       P06351   G08ab6   H3 histone; family 3B (H3.3B)   2448.264   2770   2042.864   2421.658   −2.61E−01   1.80E−01   3   Unchanged High       P04792   A16ef5   heat shock 27 kD protein 1   41952.14   34500   31970.86   36135.19   −3.92E−01   −2.83E−01   3   Unchanged High       P11021   H01ef1   heat shock 70 kD protein 5 (glucc             3226.183   1600   4101.742   2976.537   3.46E−01   −1.01E+00   3   Unchanged High       P38646   O19ab7   heat shock 70 kD protein 9B (mor             2851.743   2180   2220.509   2417.791   −3.61E−01   −3.87E−01   3   Unchanged High       Q9UK78   J14ef1   hematological and neurological              26342.33   35400   41099.58   34286.74   6.42E−01   4.27E−01   3   Unchanged High       P09651   F12ab7   heterogeneous nuclear ribonucle             2522.253   1650   2524.082   2231.413   1.05E−03   −6.14E−01   3   Unchanged High       Q9Y4J5   I23ef1   heterogeneous nuclear ribonucle             3825.912   2370   3770.457   3320.487   −2.11E−02   −6.94E−01   3   Unchanged High       P09429   F10ab7   high-mobility group (nonhistone              2534.273   1660   3502.047   2567.093   4.67E−01   −6.06E−01   3   Unchanged High       P49773   M03ef6   histidine triad nucleotide binding   6025.978   7790   7379.267   7064.436   2.92E−01   3.70E−01   3   Unchanged High       Q92769   N05ab4   histone deacetylase 2   2454.324   2220   1789.508   2155.575   −4.56E−01   −1.43E−01   3   Unchanged High       P17693   F08ab7   HLA-G histocompatibility antigen   2048.009   2780   1844.177   2225.106   −1.51E−01   4.42E−01   3   Unchanged High       P17483   C15gh2   homeo box B4   2892.488   3490   2902.69   3095.004   5.08E−03   2.71E−01   3   Unchanged High       Q9UL99   C01cd8   hyaluronoglucosaminidase 4   3623.461   2050   2189.656   2621.286   −7.27E−01   −8.21E−01   3   Unchanged High       Q9GZT3   L18gh7   hypothetical protein DC50   3343.922   3750   4298.676   3797.943   3.62E−01   1.66E−01   3   Unchanged High       Q9NWY5   O12gh2   hypothetical protein FLJ20533   3104.471   5460   6184.227   4915.419   9.94E−01   8.14E−01   3   Unchanged High       Q9UI30   P08ef2   hypothetical protein HSPC152   3000.217   4060   4396.862   3819.313   5.51E−01   4.37E−01   3   Unchanged High       Q9BQB6   P08gh5   hypothetical protein IMAGE3455:   3599.509   5410   8687.307   5897.337   1.27E+00   5.87E−01   3   Unchanged High       Q9BWJ5   P18gh7   hypothetical protein MGC3133   2074.073   2520   2719.671   2436.767   3.91E−01   2.79E−01   3   Unchanged High       Q9Y683   N11ef2   hypothetical protein MGC8721   2425.475   2730   2939.253   2699.545   2.77E−01   1.73E−01   3   Unchanged High       Q16665   P01ef6   hypoxia-inducible factor 1; alpha   3544.753   2960   1526.935   2675.668   −1.22E+00   −2.62E−01   3   Unchanged High       O75353   G04ef6   immediate early response 3   4564.408   4690   3129.721   4129.098   −5.44E−01   4.01E−02   3   Unchanged High       Q16270   J15ab6   insulin-like growth factor binding   6185.622   21800   18047.34   15334.47   1.54E+00   1.82E+00   3   Unchanged High       Q9Y287   A03gh2   integral membrane protein 2B   6908.997   10500   10014.47   9139.933   5.36E−01   6.03E−01   3   Unchanged High       P56537   D16ab6   integrin beta 4 binding protein   2594.316   3270   1568.747   2476.062   −7.26E−01   3.32E−01   3   Unchanged High       P26006   D08ab6   integrin; alpha 3 (antigen CD49C             2669.777   2740   1339.712   2249.026   −9.95E−01   3.62E−02   3   Unchanged High       Q13907   A24ab7   Isopentenyl-diphosphate delta is             2958.139   1660   2475.365   2362.933   −2.57E−01   −8.38E−01   3   Unchanged High       P33947   K03cd7   KDEL (Lys-Asp-Glu-Leu) endop             1667.246   1250   3924.993   2281.692   1.24E+00   −4.12E−01   3   Unchanged High       P00338   D15ab7   lactate dehydrogenase A   44081.29   34500   42150.03   40260.24   −6.46E−02   −3.52E−01   3   Unchanged High       P08865   G21ef7   laminin receptor 1 (6 7 kD; riboso             8548.245   6070   9921.409   8180.607   2.15E−01   −4.93E−01   3   Unchanged High       Q08380   D17ab7   lectin; galactoside-binding; solub   2294.491   2850   3014.02   2719.794   3.94E−01   3.13E−01   3   Unchanged High       O14949   F17ef3   low molecular mass ubiquinone-             2942.579   3550   3637.463   3377.305   3.06E−01   2.71E−01   3   Unchanged High       Q15012   F20ef4   lysosomal-associated protein tra             2815.002   4690   5453.634   4319.567   9.54E−01   7.36E−01   3   Unchanged High       P14174   J05ef7   macrophage migration Inhibitory   5544.722   6700   6763.718   6337.062   2.87E−01   2.74E−01   3   Unchanged High       P49006   M05ef6   macrophage myristoylated alanir   5857.382   10400   8986.315   8400.725   6.17E−01   8.22E−01   3   Unchanged High       P30463   G10ab6   major histocompatibility complex;   2701.757   4890   2255.929   3281.592   −2.60E−01   8.55E−01   3   Unchanged High       P10321   A01cd2   major histocompatibility complex;   8949.086   17000   10196.88   12044.89   1.88E−01   9.25E−01   3   Unchanged High       P10321   H12cd2   major histocompatibility complex;   7187.905   21600   11111.54   13298.19   6.28E−01   1.59E+00   3   Unchanged High       P10321   P12cd2   major histocompatibility complex;   13121.35   16800   11725.68   13868.02   −1.62E−01   3.53E−01   3   Unchanged High       P13747   M24ab7   major histocompatibility complex;   2540.911   2790   2053.351   2460.503   −3.07E−01   1.33E−01   3   Unchanged High       Q95HC0   P02gh6   major histocompatibility complex;   5067.294   4140   3295.115   4168.835   −6.21E−01   −2.90E−01   3   Unchanged High       P13640   D13gh6   metallothionein 1G   6180.376   4750   2940.683   4624.849   −1.07E+00   −3.79E−01   3   Unchanged High       P80297   D17gh6   metallothionein 1X   4881.982   5310   5233.749   5142.996   1.00E−01   1.22E−01   3   Unchanged High       P02795   L04ab7   metallothionein 2A   6620.235   7330   8067.274   7340.215   2.85E−01   1.48E−01   3   Unchanged High       O14880   E04ab7   microsomal glutathione S-transfe   5023.542   7940   4177.165   5712.043   −2.66E−01   6.60E−01   3   Unchanged High       Q9NYZ2   M22ef2   mitochondrial solute carrier   2488.07   2850   2240.824   2527.436   −1.51E−01   1.98E−01   3   Unchanged High       P26038   K05ab7   moesin   4260.51   4580   3801.298   4212.427   −1.65E−01   1.03E−01   3   Unchanged High       O15329   O12ef1   mucin 6; gastric   5574.093   5950   6685.047   6068.269   2.62E−01   9.31E−02   3   Unchanged High       P16475   J02gh1   myosin; light polypeptide 6; alkal   48122.62   45200   48882.54   47407.02   2.26E−02   −8.99E−02   3   Unchanged High       P19105   N03cd6   myosin; light polypeptide; regula             7920.873   8150   7228.401   7764.994   −1.32E−01   4.04E−02   3   Unchanged High       Q9UK23   D06ef1   N-acetylglucosamine-1-phospho             1884.596   2680   2511.293   2357.087   4.14E−01   5.05E−01   3   Unchanged High       O15239   E22ab7   NADH dehydrogenase (ubiquino             2859.738   5440   3719.503   4005.894   3.79E−01   9.27E−01   3   Unchanged High       O00483   J02ab7   NADH dehydrogenase (ubiquino             5214.222   5540   9086.615   6613.046   8.01E−01   8.70E−02   3   Unchanged High       O75438   J04ab8   NADH dehydrogenase (ubiquino             1628.024   2170   2842.647   2212.932   8.04E−01   4.13E−01   3   Unchanged High       O95168   J08ab8   NADH dehydrogenase (ubiquino             2297.787   3270   2253.854   2607.423   −2.79E−02   5.09E−01   3   Unchanged High       O95298   J12ab8   NADH dehydrogenase (ubiquino             1909.371   2840   2888.281   2544.679   5.97E−01   5.71E−01   3   Unchanged High       O43920   J18ab8   NADH dehydrogenase (ubiquino             6241.135   11500   8014.187   8594.08   3.61E−01   8.85E−01   3   Unchanged High       Q13765   H09ab7   nascent-polypeptide-associated              2800.535   3390   3897.956   3363.371   4.77E−01   2.76E−01   3   Unchanged High       Q15843   K13cd1   neural precursor cell expressed;   3449.484   4710   4139.56   4098.747   2.63E−01   4.48E−01   3   Unchanged High       Q9NX14   C01gh3   neuronal protein 17.3   3476.812   3150   5077.834   3902.8   5.46E−01   −1.41E−01   3   Unchanged High       Q9Y2R6   F18gh6   NICE-3 protein   1763.974   2250   2329.521   2113.511   4.01E−01   3.49E−01   3   Unchanged High       Q15668   H13cd6   Niemann-Pick disease; type C2   1516.592   3640   2828.255   2662.845   8.99−01   1.26E+00   3   Unchanged High       O14597   J21ef4   non-functional folate binding pro             2917.293   2170   3004.012   2697.108   4.23E−02   −4.27E−01   3   Unchanged High       P15531   E02ef5   non-metastatic cells 1; protein (N   6653.515   6940   7836.897   7143.349   2.36E−01   6.07E−02   3   Unchanged High       P22392   L12cd2   non-metastatic cells 2; protein (N   4827.494   5680   4836.596   5114.664   2.72E−03   2.35E−01   3   Unchanged High       O00746   D04ef7   non-metastatic cells 4; protein e             2211.058   2270   4300.604   2927.223   9.60E−01   3.80E−02   3   Unchanged High       O75534   B01cd4   NRAS-related gene   3478.657   3510   2737.425   3241.269   −3.46E−01   1.20E−02   3   Unchanged High       Q9H9A1   C24gh6   nuclear receptor co-repressor/H             5951.715   3290   2990.083   4076.544   −9.93E−01   −8.56E−01   3   Unchanged High       Q9NPE3   K15ef4   nucleolar protein family A; memb   3543.239   7130   3639.205   4771.656   3.86E−02   1.01E+00   3   Unchanged High       P54368   G10ef1   ornithine decarboxylase anlizym             7212.068   6880   7782.339   7292.818   1.10E−01   −6.72E−02   3   Unchanged High       Q9UH52   L23cd8   over-expressed breast tumor pro   2335.527   2320   1884.264   2181.482   −3.10E−01   −6.73E−03   3   Unchanged High       Q15070   A09cd1   oxidase (cytochrome c) assembly   2161.529   2500   1436.463   2031.796   −5.90E−01   2.08E−01   3   Unchanged High       Q9H230   G14gh5   p53-induced protein PIGPC1   1823.554   3330   1443.914   2199.367   −3.37E−01   8.69E−01   3   Unchanged High       O60356   M03cd8   p8 protein (candidate of metasta             1774.942   1940   2740.792   2150.631   6.27E−01   1.25E−01   3   Unchanged High       P78337   M22ab8   paired-like homeodomain transcr   15428.96   13300   14490.63   14411.94   −9.05E−02   −2.12E−01   3   Unchanged High       Q9C086   P20gh7   PAP-1 binding protein   2992.2   3610   5014.215   3872.969   7.45E−01   2.72E−01   3   Unchanged High       Q15165   D06ef6   paraoxonase 2   1325.972   3740   2122.119   2394.717   6.78E−01   1.49E+00   3   Unchanged High       P20962   N13ab8   parathymosin   2345.869   2330   3489.616   2722.317   5.73E−01   −8.88E−03   3   Unchanged High       P23284   I17ab8   peptidylprolyl isomerase B (cyclo   5298.839   5860   8890.43   6683.166   7.47E−01   1.45E−01   3   Unchanged High       Q06830   E18ab8   peroxiredoxin 1   2973.862   2450   2056.112   2493.75   −5.32E−01   −2.79E−01   3   Unchanged High       P32119   G04ef7   peroxiredoxin 2   3141.718   3330   2921.471   3130.835   −1.05E−01   8.37E−02   3   Unchanged High       P30048   N09ab2   peroxiredoxin 3   2420.936   2010   1671.796   2035.218   −5.34E−01   −2.66E−01   3   Unchanged High       Q13162   N07ab2   peroxiredoxin 4   2744.707   2080   3645.718   2822.139   4.10E−01   −4.03E−01   3   Unchanged High       P30044   P15cd7   peroxiredoxin 5   2205.14   3820   1714.041   2581.24   −3.63E−01   7.94E−01   3   Unchanged High       Q13492   B13cd4   phosphatidylinositol binding clat             2688.917   2690   1861.508   2414.998   −5.31E−01   3.03E−03   3   Unchanged High       P08237   P02ab7   phosphofructokinase; muscle   2790.708   1980   2829.743   2533.875   2.00E−02   −4.94E−01   3   Unchanged High       P00558   P06ab7   phosphoglycerate kinase 1   5186.346   5130   6341.68   5552.736   2.90E−01   −1.57E−02   3   Unchanged High       P18669   K14ab8   phosphoglycerate mutase 1 (brai   1847.463   2730   2859.446   2477.75   6.30E−01   5.61E−01   3   Unchanged High       Q14801   B01cd8   phosphoprotein enriched in astrc   23286.56   17400   19729.36   20128.93   −2.39E−01   −4.23E−01   3   Unchanged High       O14832   A04cd1   phytanoyl-CoA hydroxylase (Ref             7333.104   7780   8341.917   7819.036   1.86E−01   8.57E−02   3   Unchanged High       P53801   L01ef1   pituitary tumor-transforming 1 int             4385.308   5330   4172.137   4627.881   −7.19E−02   2.80E−01   3   Unchanged High       Q9HB21   E19gh5   pleckstrin homology domain-con             2318.08   3070   2907.381   2766.359   3.27E−01   4.07E−01   3   Unchanged High       Q15365   O09cd1   poly(rC) binding protein 1   4617.635   3130   3156.644   3635.431   −5.49E−01   −5.60E−01   3   Unchanged High       P52433   B17ab8   polymerase (RNA) II (DNA direct   2157.353   3780   3657.763   3198.285   −7.62E−01   8.09E−01   3   Unchanged High       P52436   L16gh1   polymerase (RNA) II (DNA direct   2161.398   2600   2709.495   2489.343   3.26E−01   2.65E−01   3   Unchanged High       Q03052   B19ab8   POU domain; class 3; transcripti             3321.206   2650   2251.677   2740.913   −5.61E−01   −3.26E−01   3   Unchanged High           K20gh5   PP1201 protein   7127.293   6650   2688.636   5487.085   −1.41E+00   −1.01E−01   3   Unchanged High       P40425   G08ab8   pre-B-cell leukemia transcription   2817.191   2650   3413.81   2958.976   −2.77E−01   −9.05E−02   3   Unchanged High       Q99471   K06ab8   prefoldin 5   1827.777   2160   2837.334   2275.038   6.34E−01   2.41E−01   3   Unchanged High       Q9UHZ2   E21ef8   PRO1073 protein   1872.208   3140   1690.101   2234.209   −1.48E−01   7.46E−01   3   Unchanged High       P07737   A21cd1   profilin 1   29650.38   48900   35394.8   37970.06   2.55E−01   7.21E−01   3   Unchanged High       Q92740   E03gh1   prosaposin (variant Gaucher dis             4235.232   5370   4268.459   4622.898   2.55E−01   3.41E−01   3   Unchanged High       P07478   N02cd2   protease; serine; 2 (trypsin 2)   77359.27   42600   51746.68   57240.67   1.13E−02   −8.60E−01   3   Unchanged High       Q9UL46   N09ab8   proteasome (prosome; macropa             3682.153   4550   2712.172   3648.995   −5.80E−01   3.06E−01   3   Unchanged High       P25786   L09ef7   proteasome (prosome; macropa             2270.079   2570   2265.763   2369.437   −4.41E−01   1.80E−01   3   Unchanged High       P20618   J17ab8   proteasome (prosome; macropa             2835.653   3590   2820.916   3082.003   −7.52E−03   3.40E−01   3   Unchanged High       P49720   J21ab8   proteasome (prosome; macropa             1714.767   2100   2435.426   2081.991   5.06E−01   2.89E−01   3   Unchanged High       P28070   J23ab8   proteasome (prosome; macropa             2193.138   1760   2224.325   2058.212   2.04E−02   −3.20E−01   3   Unchanged High       Q99436   L03ab8   proteasome (prosome; macropa             4179.694   3450   3072.098   3566.368   −4.44E−01   −2.78E−01   3   Unchanged High       Q15249   H13ef5   prothymosin; alpha (gene seque             11382.44   14500   9974.587   11954.68   −1.90E−01   3.50E−01   3   Unchanged High       Q9NQ11   G03gh7   putative ATPase   2774.724   2460   2271.593   2501.162   −2.89E−01   −1.75E−01   3   Unchanged High       P41567   N06cd5   putative translation initiation fact             7487.872   6600   8909.545   7666.779   2.51E−01   −1.81E−01   3   Unchanged High       Q15181   L18gh1   pyrophosphatase (Inorganic)   4914.897   4350   2667.605   3978.537   −8.82E−01   −1.75E−01   3   Unchanged High       P14788   M24ab8   pyruvate kinase; muscle   6305.222   8060   9000.504   7787.922   5.13E−01   3.54E−01   3   Unchanged High       P57735   G12gh4   RAB25; member RAS oncogene   3343.628   4890   1366.379   3198.699   −1.29E+00   5.47E−01   3   Unchanged High       P54725   E21cd1   RAD23 homolog A ( S. cerevisiae     2533.36   1790   1753.113   2026.126   −5.31E−01   −5.00E−01   3   Unchanged High       P54727   M10ef6   RAD23 homolog B ( S. cerevisiae     4038.864   5410   4983.21   4809.132   3.03E−01   4.20E−01   3   Unchanged High       O00538   P16cd5   RAS guanyl releasing protein 2 (             2418.688   2310   1906.199   2210.191   −3.44E−01   −6.90E−02   3   Unchanged High       P06749   C21gh1   ras homolog gene family; memb             2136.708   1940   3003.841   2358.668   4.91E−01   −1.43E−01   3   Unchanged High       P08134   B16ab2   ras homolog gene family; memb             4404.567   4490   2930.236   3943.029   −5.88E−01   2.91E−02   3   Unchanged High           P06gh8   ras-like protein VTS58635   5451.542   6580   9066.798   7033.479   7.34E−01   2.72E−01   3   Unchanged High       P15154   C01ef6   ras-related C3 botulinum toxin s             10849.13   9720   10044.19   10202.94   −1.11E−01   −1.59E−01   3   Unchanged High       Q15347   B20cd6   Ras-related GTP-binding protein   1728.963   2380   2623.418   2244.978   6.02E−01   4.63E−01   3   Unchanged High       O95197   A06cd6   reticuion 3   3712.756   3420   3833.411   3654.06   4.61E−02   −1.20E−01   3   Unchanged High       P09455   F12ab8   retinol binding protein 1; cellular   2211.12   4480   2383.274   3023.27   1.08E−01   1.02E+00   3   Unchanged High       P52565   K13ef6   Rho GDP dissociation inhibitor (             3166.04   3200   3141.434   3169.009   −1.13E−02   1.52E−02   3   Unchanged High       P27635   N19cd2   ribosomal protein L10   13406.29   7100   11103.69   10536.25   −2.72E−01   −9.17E−01   3   Unchanged High       P53025   G22cd1   ribosomal protein L10a   19374.73   15100   19939.26   18124.91   4.14E−02   −3.63E−01   3   Unchanged High       P39026   D07cd1   ribosomal protein L11   14172.29   6760   10346.92   10427.07   −4.54E−01   −1.07E+00   3   Unchanged High       P30050   D09cd1   ribosomal protein L12   38376.69   24500   38669.34   33860.13   1.10E−02   −6.45E−01   3   Unchanged High       P40429   A01ef1   ribosomal protein L13a   23800.5   22200   28159.37   24735.85   2.43E−01   −9.73E−02   3   Unchanged High       P50914   B18cd4   ribosomal protein L14   18507.36   14600   16108.18   16402.14   −2.00E−01   −3.43E−01   3   Unchanged High       P39030   C13cd3   ribosomal protein L15   8407.532   8100   10809.12   9104.589   3.62E−01   −5.43E−02   3   Unchanged High       P18621   D19cd1   ribosomal protein L17   8779.141   8440   10004.78   9074.168   1.89E−01   −5.71E−02   3   Unchanged High       Q07020   D13cd1   ribosomal protein L18   12168.43   10200   15619.17   12658.45   3.60E−01   −2.56E−01   3   Unchanged High       Q02543   C15gh1   ribosomal protein L18a   24976.59   27200   28170.19   26796.74   1.74E−01   1.25E−01   3   Unchanged High       P14118   D15cd1   ribosomal protein L19   6226.589   5530   5535.643   5762.718   −1.70E−01   −1.72E−01   3   Unchanged High       P46778   A13cd3   ribosomal protein L21   11156.59   11800   16742.21   13222.79   5.86E−01   7.72E−02   3   Unchanged High       P35268   D17cd1   ribosomal protein L22   16289.45   16200   18991.35   17168.94   2.21E−01   −5.63E−03   3   Unchanged High       P23131   F11cd4   ribosomal protein L23   20972.93   20400   25729.93   22356.23   2.95E−01   −4.24E−02   3   Unchanged High       P29316   G09cd3   ribosomal protein L23a   6385.675   4840   5446.963   5556.302   −2.29E−01   −4.01E−01   3   Unchanged High       P38663   D21cd1   ribosomal protein L24   7805.803   6180   5479.195   6488.503   −5.11E−01   −3.37E−01   3   Unchanged High       P08526   F01cd1   ribosomal protein L27   12874.22   5280   10256.69   9469.252   −3.28E−01   −1.29E+00   3   Unchanged High       P46776   F05cd1   ribosomal protein L27a   16046.37   17000   20949.85   18008.07   3.85E−01   8.57E−02   3   Unchanged High       P46779   F07cd1   ribosomal protein L28   40540.59   32400   45810.52   39577.25   1.76E−01   −3.24E−01   3   Unchanged High       P47914   E23cd3   ribosomal protein L29   3346.473   1960   1947.028   2417.223   −7.81E−01   −7.73E−01   3   Unchanged High       P39023   B21cd1   ribosomal protein L3   13192.5   10500   13962.55   12535.38   8.18E−02   −3.36E−01   3   Unchanged High       P04645   F03cd1   ribosomal protein L30   17693.61   12300   21530.83   17188.03   2.83E−01   −5.20E−01   3   Unchanged High       P12947   F09cd1   ribosomal protein L31   9749.468   8980   12591.65   10441.63   3.69E−01   −1.18E−01   3   Unchanged High       P02433   A15cd3   ribosomal protein L32   22774.44   24400   30742.77   25982.45   4.33E−01   1.01E−01   3   Unchanged High       P49207   F11cd1   ribosomal protein L34   13251.1   11500   13193.66   12661.96   −6.27E−03   −1.99E−01   3   Unchanged High       P42766   K16cd7   ribosomal protein L35   10454.27   10500   10655.65   10527.37   2.75E−02   2.47E−03   3   Unchanged High       P18077   F13cd1   ribosomal protein L35a   14583.91   10700   8811.726   11356.13   −7.27E−01   −4.50E−01   3   Unchanged High       P09896   J06gh1   ribosomal protein L36a   8395.644   8780   12052.18   9742.196   5.22E−01   8.44E−02   3   Unchanged High       P09896   A19cd3   ribosomal protein L36a-like   5167.775   5750   4693.401   5203.379   −1.39E−01   1.54E−01   3   Unchanged High       P02403   F15cd1   ribosomal protein L37   31895.4   45000   41301.54   39386.47   3.73E−01   4.95E−01   3   Unchanged High       P12751   F17cd1   ribosomal protein L37a   18652.48   17300   19955.82   18651.98   9.74E−02   −1.05E−01   3   Unchanged High       P23411   F19cd1   ribosomal protein L38   5149.82   5570   7560.21   6091.715   5.54E−01   1.12E−01   3   Unchanged High       P02404   A17cd3   ribosomal protein L39   14114.05   21300   22827.16   19427.01   6.94E−01   5.96E−01   3   Unchanged High       P36578   B23cd1   ribosomal protein L4   14367.47   10400   10448.85   11723.95   −4.59E−01   −4.72E−01   3   Unchanged High       P28751   L06gh1   ribosomal protein L41   35135.75   34300   40372.62   36614.61   2.00E−01   −3.32E−02   3   Unchanged High       P46777   E21cd3   ribosomal protein L5   12002.66   8880   10351.69   10411.06   −2.13E−01   −4.35E−01   3   Unchanged High       Q02878   D01cd1   ribosomal protein L6   15861.7   7300   10119.01   11094.61   −6.48E−01   −1.12E+00   3   Unchanged High       P18124   D03cd1   ribosomal protein L7   21230.67   15900   19538.32   18885.03   −1.20E−01   −4.18E−01   3   Unchanged High       P11518   G11cd3   ribosomal protein L7a   13385.5   8240   10586.53   10736.39   −3.38E−01   −7.00E−01   3   Unchanged High       P25120   D05cd1   ribosomal protein L8   23580.43   18300   24766.14   22208.81   7.08E−02   −3.67E−01   3   Unchanged High       P32969   B19cd1   ribosomal protein L9   28853.42   32200   37288.41   32766.75   3.70E−01   1.56E−01   3   Unchanged High       P46783   H13cd1   ribosomal protein S10   7453.342   7660   7511.766   7540.695   1.13E−02   3.89E−02   3   Unchanged High       P04643   H15cd1   ribosomal protein S11   13429.85   15600   13623.52   14209.6   2.07E−02   2.14E−01   3   Unchanged High       P25398   H17cd1   ribosomal protein S12   16170.73   10600   12294.27   13018.69   −3.95E−01   −6.11E−01   3   Unchanged High       Q02546   H19cd1   ribosomal protein S13   13956.88   12600   15289.54   13946.74   1.32E−01   −1.48E−01   3   Unchanged High       P11174   H21cd1   ribosomal protein S15   21322.73   19600   23334.6   21408.92   1.30E−01   −1.24E−01   3   Unchanged High       P39027   H23cd1   ribosomal protein S15a   16787.1   15100   21854.01   17912.92   3.81E−01   −1.53E−01   3   Unchanged High       P17008   J01cd1   ribosomal protein S16   26604.5   15700   24481.55   22257.3   −1.20E−01   −7.62E−01   3   Unchanged High       P08708   J03cd1   ribosomal protein S17   13979.25   7990   15360.88   12443.09   1.36E−01   −8.07E−01   3   Unchanged High       P25232   A17gh2   ribosomal protein S18   12558.18   12600   20093.07   15089.7   6.78E−01   6.84E−03   3   Unchanged High       P17075   J07cd1   ribosomal protein S20   21944.13   19900   31381.43   24400.98   5.16E−01   −1.43E−01   3   Unchanged High       P35265   D24ef7   ribosomal protein S21   14046.7   9470   9023.678   10847.43   −6.38E−01   −5.69E−01   3   Unchanged High       P39028   J09cd1   ribosomal protein S23   12228.98   10900   14550.17   12545.6   2.51E−01   −1.72E−01   3   Unchanged High       P16632   J11cd1   ribosomal protein S24   12913.37   13100   12135.49   12699.84   −8.96E−02   1.53E−02   3   Unchanged High       P25111   J13cd1   ribosomal protein S25   6274.159   5630   5123.747   5677.337   −2.92E−01   −1.55E−01   3   Unchanged High       P02383   C01cd3   ribosomal protein S26   26138.26   30900   19440.2   25499.92   −4.27E−01   2.42E−01   3   Unchanged High       P42677   G01cd3   ribosomal protein S27 (metallop             17556.94   12800   20383.13   16927.4   2.15E−01   −4.51E−01   3   Unchanged High       P14798   B18cd1   ribosomal protein S27a   3284.551   3180   2757.252   3073.17   −2.52E−01   −4.77E−02   3   Unchanged High       P25112   J15cd1   ribosomal protein S28   30384.24   32000   28529.21   30318.47   −9.09E−02   7.66E−02   3   Unchanged High       P30054   J17cd1   ribosomal protein S29   18454.55   20900   25539.27   21630.2   4.69E−01   1.79E−01   3   Unchanged High       P23396   H03cd1   ribosomal protein S3   5913.682   2830   5523.561   4754.218   −9.85E−02   −1.07E+00   3   Unchanged High       P49241   O16ef5   ribosomal protein S3A   7154.088   6200   8592.248   7316.667   2.64E−01   −2.06E−01   3   Unchanged High       P12750   A21cd3   ribosomal protein S4; X-linked   19821.56   16200   21778.05   19282.5   1.36E−01   −2.87E−01   3   Unchanged High       P22090   A23cd3   ribosomal protein S5; Y-linked   2629.697   2330   2779.184   2580.924   7.98E−02   −1.72E−01   3   Unchanged High       P46782   H05cd1   ribosomal protein S5   15421.08   11000   17355.54   14598.96   1.70E−01   −4.85E−01   3   Unchanged High       P10860   H07cd1   ribosomal protein S6   46408.18   26100   40579.46   37695.24   −1.94E−01   −8.30E−01   3   Unchanged High       P46781   H12cd5   ribosomal protein S9   8827.416   9710   15295.98   11278.36   7.93E−01   1.38E−01   3   Unchanged High       P46781   P12cd5   ribosomal protein S9   9059.523   1790   5725.082   5525.883   −6.62E−01   −2.34E+00   3   Unchanged High       P05387   H01cd1   ribosomal protein; large P2   16611.14   12700   17775.72   15695.14   9.78E−02   −3.87E−01   3   Unchanged High       P05388   F21cd1   ribosomal protein; large; P0   17127.41   12400   19746.88   16430.54   2.05E−01   −4.64E−01   3   Unchanged High       P05386   F23cd1   ribosomal protein; large; P1   2228.298   1880   3134.529   2413.78   4.92E−01   −2.46E−01   3   Unchanged High       Q9Y254   C08ef3   ring-box 1   2597.578   4260   3365.165   3408.892   3.74E−01   7.15E−01   3   Unchanged High       Q9NWJ8   A23gh3   roundabout homolog 4; magic              1969.602   3940   2093.279   2666.66   8.79E−02   9.99E−01   3   Unchanged High       P08206   D06cd1   S100 calcium binding protein A1             38485.73   49800   31745.47   40017.88   −2.78E−01   3.72E−01   3   Unchanged High       P31949   E09cd3   S100 calcium binding protein A1             8890.594   11100   5408.269   8466.714   −7.17E−01   3.20E−01   3   Unchanged High       P06703   P17gh6   S100 calcium binding protein A6   3403.146   4070   2088.478   3188.753   −7.04E−01   2.60E−01   3   Unchanged High       P55735   J04ef4   SEC 13-like 1 ( S. cerevisiae )   1695.152   1990   2362.541   2016.062   4.79E−01   2.32E−01   3   Unchanged High       P38384   I06ef3   Sec61 gamma   5653.955   7820   7254.423   6908.432   3.60E−01   4.67E−01   3   Unchanged High       Q9NZJ3   H06ef2   selenoprotein T   2923.813   2440   1325.491   2230.091   −1.14E+00   −2.60E−01   3   Unchanged High       O15532   H16cd1   selenoprotein W; 1   2678.843   2970   3918.44   3189.642   5.49E−01   1.50E−01   3   Unchanged High       Q13501   J23cd4   sequestosome 1   3214.395   3170   1164.17   2517.543   −1.47E+00   −1.82E−02   3   Unchanged High       P35237   L18ab8   serine (or cysteine) proteinase in   4203.074   8180   2936.72   5105.477   −5.17E−01   9.60E−01   3   Unchanged High       P05121   P05ef7   serine (or cysteine) proteinase in   4454.56   7280   9179.863   6972.284   1.04E+00   7.09E−01   3   Unchanged High       Q00587   C14cd7   serum constituent protein   2480.698   2660   2044.608   2393.46   −2.79E−01   9.80E−02   3   Unchanged High       Q9H299   P16gh7   SH3 domain binding glutamic aci   14473.6   17100   13798.02   15134.74   −6.90E−02   2.43E−01   3   Unchanged High       P37108   E21cd2   signal recognition particle 14 kD (   24326.27   35600   24319.59   28082.56   −3.96E−04   5.49E−01   3   Unchanged High       P49458   E19cd2   signal recognition particle 9 kD   1874.967   2640   3141.422   2551.928   7.45E−01   4.93E−01   3   Unchanged High       P43308   G15cd2   signal sequence receptor; beta (             4209.147   4810   5876.451   4898.581   4.81E−01   1.31E−01   3   Unchanged High       P51571   O15gh1   signal sequence receptor; delta (   2062.113   2330   2654.968   2349.29   3.65E−01   1.77E−01   3   Unchanged High       O00422   M17cd6   sin3-associated polypeptied; 18 k   2502.79   2610   2079.295   2396.002   −2.67E−01   5.83E−02   3   Unchanged High       O75918   J10cd5   small EDRK-rich factor 2   5927.595   7010   7926.059   6955.245   4.19E−01   2.42E−01   3   Unchanged High       P13500   C15cd3   small inducible cytokine A2 (mon   17077.97   38100   8786.323   21330.26   −9.59E−01   1.16E+00   3   Unchanged High       Q15356   A09cd2   small nuclear ribonucleoprotein              2743.428   2150   2819.855   2570.901   3.96E−02   −3.52E−01   3   Unchanged High       P14648   A13cd2   small nuclear ribonucleoprotein              899.6242   2800   2362.597   2021.429   1.39E+00   1.64E+00   3   Unchanged High       P12236   G01ef1   solute carrier family 25 (mitochor   7384.066   4760   6176.034   6107.995   −2.58E−01   −6.32E−01   3   Unchanged High       Q00325   K22ab8   solute carrier family 25 (mitochor   5074.308   3750   3779.577   4200.626   −4.25E−01   −4.37E−01   3   Unchanged High       P32745   N01cd1   somatostalin receptor 3   4102.668   4170   4748.989   4340.964   2.11E−01   2.39E−02   3   Unchanged High       P30626   E13cd2   sorcin   1895.592   2790   2280.297   2323.149   2.67E−01   5.59E−01   3   Unchanged High       Q01826   F18ef6   special AT-rich sequence bindin             26449.32   41300   24225.61   30645.09   −1.27E−01   6.42E−01   3   Unchanged High       P21673   D12cd1   spermidine/spermine N1-acetylin   8349.882   16500   6013.659   10275.93   −4.74E−01   9.80E−01   3   Unchanged High       P34991   G05cd3   S-phase kinase-associated prote   3072.601   2990   2396.506   2820.643   −3.59E−01   −3.80E−02   3   Unchanged High       P23246   B09cd2   splicing factor proline/glutamine              2694.629   2460   3348.423   2834.056   3.13E−01   −1.32E−01   3   Unchanged High       P35716   C07cd2   SRY (sex determining region Y)-             5019.988   4860   2125.089   4001.241   −1.24E+00   −4.71E−02   3   Unchanged High       P35713   E10ef4   SRY (sex determining region Y)-             2575.791   3100   2024.386   2565.998   −3.48E−01   2.66E−01   3   Unchanged High       Q06945   C05cd2   SRY (sex determining region Y)-             2299.474   2210   1636.067   2049.214   −4.91E−01   −5.59E−02   3   Unchanged High       P00441   G20ef7   superoxide dismutase 1; soluble   4439.342   4930   3239.195   4202.954   −4.55E−01   1.51E−01   3   Unchanged High       P50502   I18cd2   suppression of tumorigenicity 13   2307.599   2530   2358.117   2400.085   3.12E−02   1.35E−01   3   Unchanged High       Q9Y5Y6   P20gh1   suppression of tumorigenicity 14   2358.28   2700   1494.856   2183.041   −6.58E−01   1.93E−01   3   Unchanged High       P17600   J06cd2   synapsin I   1969.157   2220   2010.908   2067.417   3.03E−02   1.74E−01   3   Unchanged High       O43759   G11cd5   synaptogyrin 1   14516.6   10700   10060.61   11775.53   −5.29E−01   −4.33E−01   3   Unchanged High       Q12962   P19cd2   TAF10 RNA polymerase II; TATA   5937.255   5080   3962.323   4992.528   −5.83E−01   −2.26E−01   3   Unchanged High       Q15763   B20cd2   t-complex-associated-testis-expn   2022.997   2890   2885.017   2600.459   5.12E−01   5.16E−01   3   Unchanged High       P10599   B23cd4   thioredoxin   11525.16   11900   6440.37   9965.777   −8.40E−01   5.00E−02   3   Unchanged High       P13472   O02ef7   thymosin; beta 10   46982.91   74300   54263.48   58508.68   2.08E−01   6.61E−01   3   Unchanged High       P01253   L12gh1   thymosin; beta 4; X chromosome   23145.54   26000   16231.51   21783.42   −5.12E−01   1.66E−01   3   Unchanged High       Q01085   C02cd2   TIA1 cytotoxic granule-associate   2250.456   1770   2917.342   2312.231   3.74E−01   −3.47E−01   3   Unchanged High       Q15370   J12cd2   transcription elongation factor B              2616.595   3980   3919.327   3505.384   5.83E−01   6.05E−01   3   Unchanged High       O43680   O11cd2   transcription factor 21   1789.295   1790   3044.118   2209.014   7.67E−01   3.49E−03   3   Unchanged High       P21980   O16cd2   transglutaminase 2 (C polypeptid   3131.079   3490   1857.596   2827.774   −7.53E−01   1.58E−01   3   Unchanged High       P29401   N15cd1   transkelolase (wernicke-Korsak             3258.575   2040   2715.206   2671.504   −2.63E−01   −6.75E−01   3   Unchanged High       O60739   O01cd6   translation factor sui 1 homolog   2671.935   3400   3868.727   3315.099   5.34E−01   3.50E−01   3   Unchanged High       Q9NS69   I02gh7   translocase of outer mitochondri             2988.423   2450   3754.914   3062.809   3.29E−01   −2.89E−01   3   Unchanged High       P00938   M24cd1   triosephosphate isomerase 1   5701.29   5820   8345.738   6622.243   5.50E−01   2.97E−02   3   Unchanged High       P07226   G10cd2   tropomyosin 4   2636.256   2300   3755.882   2897.509   5.11E−01   −1.97E−01   3   Unchanged High       P04687   F09cd4   tubulin; alpha 3   20220.03   14500   22303.88   18992.31   1.42E−01   −4.84E−01   3   Unchanged High       P04687   A01cd1   tubulin; beta; ubiquitous   15258.81   7840   22478.65   15193.76   5.59E−01   −9.60E−01   3   Unchanged High       Q13509   E04cd6   tubulin; beta; 4   2338.877   2990   1853.273   2394.89   −3.36E−01   3.56E−01   3   Unchanged High       P04350   F01gh6   tubulin; beta; 5   7573.765   4430   3448.455   5149.498   −1.14E+00   −7.75E−01   3   Unchanged High       O75347   O08cd2   tubulin-specific chaperone a   3000.065   3900   3275.629   3390.719   1.27E−01   3.77E−01   3   Unchanged High       O75509   L10ef3   tumor necrosis factor receptor su   2245.338   4890   1881.231   3007.078   −2.55E−01   1.12E+00   3   Unchanged High       P13693   G16cd2   tumor protein; translationally-con   39878.18   60800   48468.25   49731.11   2.61E−01   6.10E−01   3   Unchanged High       P14625   G24cd2   tumor rejection antigen (gp96) 1   2185.187   2060   4905.342   3049.346   1.17E+00   −8.69E−02   3   Unchanged High       P42655   K04cd4   tyrosine 3-monooxygenase/trypt             6584.565   5730   5558.974   5956.713   −2.44E−01   −2.01E−01   3   Unchanged High       Q04917   G06cd3   tyrosine 3-monooxygenase/trypt             8621.322   8150   4562.366   7111.932   −9.18E−01   −8.07E−02   3   Unchanged High       P29312   A01cd4   tyrosine 3-monooxygenase/trypt             5873.282   4670   2279.148   4275.506   −1.37E+00   −3.29E−01   3   Unchanged High       P29312   P12cd4   tyrosine 3-monooxygenase/trypt             4562.964   1140   1520.2   2406.497   −1.59E+00   −2.01E+00   3   Unchanged High       O14957   G17cd7   ubiquinol-cytochrome c reductas   2728.765   3990   3332.422   3351.45   2.88E−01   5.49E−01   3   Unchanged High       P14793   D01cd4   ubiquitin A-52 residue ribosomal   3536.225   1730   3258.439   2840.732   −1.18E−01   −1.03E+00   3   Unchanged High       P02248   D22gh1   ubiquitin B   2753.942   4430   4152.235   3779.352   5.92E−01   6.86E−01   3   Unchanged High       O76069   B12cd4   ubiquitin-conjugating enzyme E2   2001.262   1980   2223.574   2068.646   1.52E−01   −1.46E−02   3   Unchanged High       Q9BZL1   B17gh7   ubiquitin-like 5   4339.474   9100   5279.835   6239.513   2.83E−01   1.07E+00   3   Unchanged High       P08670   C24cd3   vimentin   5940.876   8720   17783.4   10813.94   1.58E+00   5.53E−01   3   Unchanged High       P45880   C18cd3   voltage-dependent anion channe   7005.537   7280   4758.179   6347.014   −5.58E−01   5.49E−02   3   Unchanged High       Q9Y277   C04cd4   voltage-dependent anion channe   1863.424   2210   2573.885   2216.75   4.66E−01   2.48E−01   3   Unchanged High       P17861   O15cd4   X-box binding protein 1   3398.445   1600   2040.224   2347.333   −7.36E−01   −1.08E+00   3   Unchanged High       O43670   M04cd3   zinc finger protein 207   3338.117   3170   3176.631   3226.643   −7.15E−02   −7.67E−02   3   Unchanged High       Q07352   N21ef6   zinc finger protein 36; C3H type-I   6097.384   5750   4958.224   5601.518   −2.98E−01   −8.49E−02   3   Unchanged High       Q15942   M10cd3   zyxin   2570.21   2070   2519.748   2387.987   −2.86E−02   −3.09E−01   3   Unchanged High       Q16659   B17ef5   mitogen-activated protein kinase   144.6425   141   100.0111   128.6073   −5.32E−01   −3.51E−02   1   Unchanged Low       O75324   B05cd3   stannin   131.7242   172   100.0655   134.7009   −3.97E−01   3.88E−01   1   Unchanged Low       Q9BYP8   E16gh8   keratin associated protein 17.1   176.4958   174   100.1011   150.0893   −8.18E−01   −2.33E−02   1   Unchanged Low       P55291   J01ab4   cadherin 15; M-cadherin (myotut   158.7215   128   100.3297   128.8583   −6.62E−01   −3.16E−01   1   Unchanged Low       P49768   L14ab7   presenilin 1 (Alzheimer disease              127.9653   124   100.3504   117.5823   −3.51E−01   −4.04E−02   1   Unchanged Low       P55107   G10ab5   growth differentiation factor 10   114.7206   168   100.6326   127.9343   −1.89E−01   5.54E−01   1   Unchanged Low       P17082   P18cd7   related RAS viral (r-ras) oncoger   433.219   176   100.8465   236.7776   −2.10E+00   −1.30E+00   1   Unchanged Low       P23634   N08ab2   ATPase; Ca++ transporting; plas   179.3836   276   100.9041   185.4081   −8.30E−01   6.21E−01   1   Unchanged Low       P78347   J20ab5   general transcription factor II;              151.6834   103   100.9514   118.6963   −5.87E−01   −5.52E−01   1   Unchanged Low       P09912   F08ef7   Interferon; alpha-Inducible protein   183.6419   1050   101.0749   444.3716   −8.61E−01   2.51E+00   1   Unchanged Low       Q9H2F5   F13gh7   enhancer of polycomb 1   127.3938   115   101.3763   114.5773   −3.30E−01   −1.48E−01   1   Unchanged Low       O14811   M06cd7   programmed cell death 10   152.3457   132   101.598   128.8019   −5.85E−01   −2.02E−01   1   Unchanged Low       O60942   A17cd4   RNA guanylyltransferase and 5             176.7836   97.1   101.6765   125.1735   −7.98E−01   −8.65E−01   1   Unchanged Low       Q9Y5Y3   M18cd7   G protein-coupled receptor 45   174.3335   161   101.8478   145.8365   −7.75E−01   −1.12E−00   1   Unchanged Low       P11908   H15ab8   phosphoribosyl pyrophosphate s             166.1373   174   101.9334   147.2722   −7.05E−01   6.46E−02   1   Unchanged Low       Q92851   P18ab3   caspase 10; apoptosis-related cy             135.919   107   101.9435   115.0308   −4.15E−01   −3.42E−01   1   Unchanged Low       Q9BQE5   M03gh7   apolipoprotein L; 2   109.8196   148   102.0533   119.8218   −1.06E−01   4.26E−01   1   Unchanged Low       P55327   D05cd2   tumor protein D52   136.2596   112   102.1111   116.9522   −4.16E−01   −2.77E−00   1   Unchanged Low       P28332   K03ab2   alcohol dehydrogenase 6 (class              142.4055   97.7   102.1575   114.0924   −4.79E−01   −5.43E−01   1   Unchanged Low       O95861   E02cd6   3′(2′); 5′-bisphosphate nucleotid             128.1251   116   102.1715   115.4153   −3.27E−01   −1.44E−01   1   Unchanged Low       Q9NXJ5   A10gh2   hypothetical protein FLJ20208   122.4219   151   102.3038   125.322   −2.59E−01   3.05E−01   1   Unchanged Low       Q15642   K09gh1   thyroid hormone receptor interac   120.9158   142   102.3082   121.6641   −2.41E−01   2.30E−01   1   Unchanged Low       O94997   O09cd7   decidual protein induced by prog   174.3087   140   102.3137   138.8592   −7.69E−01   −3.17E−01   1   Unchanged Low       O95453   G02ab8   poly(A)-specific ribonuclease (de   139.9344   105   102.3217   115.7147   −4.52E−01   −4.16E−01   1   Unchanged Low       Q9H9C5   F01gh7   KIAA1453 protein   135.8299   126   102.4347   121.5247   −4.07E−01   −1.05E−01   1   Unchanged Low       P10451   B13cd1   secreted phosphoprotein 1 (oster   190.4604   76.7   102.5193   123.2388   −8.94E−01   −1.31E+00   1   Unchanged Low       P53992   B03cd5   SEC24 related gene family; mem   134.307   105   102.5437   113.9998   −3.89E−01   −3.53E−01   1   Unchanged Low       Q9NQW1   F22gh6   secretory pathway component Se             111.3643   158   102.6234   123.8833   −1.18E−01   5.02E−01   1   Unchanged Low       Q01449   A17gh5   myosin light chain 2a   179.1031   170   103.0725   150.5611   −7.97E−01   −7.94E−02   1   Unchanged Low       Q9NX46   K12gh2   hypothetical protein FLJ20446   109.5374   159   103.1083   123.8664   −8.73E−02   5.37E−01   1   Unchanged Low       P53609   A23cd1   protein geranyigeranyltransferas             140.0296   128   103.1248   123.8135   −4.41E−01   −1.28E−01   1   Unchanged Low       Q15029   J16cd4   U5 snRNP-specific protein; 116              119.3284   126   103.1503   115.9932   −2.10E−01   7.28E−02   1   Unchanged Low       P50458   O23cd5   LIM homeobox protein 2   145.905   120   103.1971   122.9669   −5.00E−01   −2.84E−01   1   Unchanged Low       P33764   B24cd1   S100 calcium binding protein A3   150.5991   204   103.3783   152.5858   −5.43E−01   4.36E−01   1   Unchanged Low       Q9P289   G03ef3   Mst3 and SOK1-related kinase   133.5225   116   103.4345   117.7841   −3.68E−01   −1.98E−01   1   Unchanged Low       P52429   P17cd3   diacylglycerol kinase; epsilon (64   128.7238   123   103.5015   118.2956   −3.15E−01   −6.96E−02   1   Unchanged Low       P54578   H17cd5   ubiquitin specific protease 14 (tR   160.7495   108   103.6864   124.2132   −6.33E−01   −5.71E−01   1   Unchanged Low       Q13219   E24ab8   pregnancy-associated plasma p             112.9052   154   103.7948   123.4254   −1.21E−01   4.44E−01   1   Unchanged Low       O60547   M12ab5   GDP-mannose 4; 6-dehydratase   147.2805   108   103.8044   119.8044   −5.05E−01   −4.43E−01   1   Unchanged Low       P23297   I17ef6   S100 calcium binding protein A1   145.2558   126   103.9033   124.9008   −4.83E−01   −2.10E−01   1   Unchanged Low       Q9H5J8   M01gh8   hypothetical protein MGC5306   216.091   91.7   104.0432   137.2762   −1.05E+00   −1.24E+00   1   Unchanged Low       Q14493   I08cd4   stem-loop (histone) binding protein   126.7755   155   104.1318   128.4702   −2.84E−01   2.85E−01   1   Unchanged Low       Q9NZU0   O16cd8   fibronectin leucine rich transmerr   284.9107   268   104.3033   219.1816   −1.45E+01   −8.65E−02   1   Unchanged Low       P80370   B01ef7   delta-like 1 homolog ( Drosophila     160.1421   80   104.328   114.8185   −6.18E−01   −1.00E+00   1   Unchanged Low       Q9NYV4   C23ef3   CDC2-related protein kinase 7   128.5947   107   104.3521   113.4542   −3.01E−01   −2.60E−01   1   Unchanged Low       P09016   C23ef5   homeo box D4   173.2254   192   104.3556   156.5829   −7.31E−01   1.50E−01   1   Unchanged Low       Q13873   A16ab3   bone morphogenetic protein rece             155.8113   86.8   104.4206   115.6624   −5.77E−01   −8.45E−01   1   Unchanged Low       O14878   B22ef4   inosine triphosphatase (nucleos             124.8814   120   104.4238   116.398   −2.58E−01   −5.89E−02   1   Unchanged Low       P52848   J01ab6   N-deacetylase/N-sulfotransferase             166.2411   84.4   104.4555   118.3793   −6.70E−01   −9.77E−01   1   Unchanged Low       Q14848   A05cd5   TNF receptor-associated factor 4   124.2461   136   104.4604   121.4689   −2.50E−01   1.27E−01   1   Unchanged Low       O00204   O04cd2   sulfotransferase family; cytosolic   185.8106   117   104.4824   135.653   −8.31E−01   −6.71E−01   1   Unchanged Low       P35610   E13gh1   sterol O-acyltransferase (acyl-Cc   143.8417   88   104.5518   112.1404   −4.60E−01   −7.08E−01   1   Unchanged Low       Q04760   L03ab5   glyoxalase I   132.6871   107   104.5782   114.7132   −3.43E−01   −3.12E−01   1   Unchanged Low       P51690   H06ab2   arylsulfatase E (chondrodysplasi   177.023   76.2   104.5865   119.2772   −7.59E−01   −1.22E+00   1   Unchanged Low       P26012   C11ef7   integrin; beta B   110.7396   170   104.6296   128.4899   −8.19E−02   6.19E−01   1   Unchanged Low       Q14978   K11cd5   nucleolar and coiled-body phosp   117.0048   131   104.685   117.4911   −1.61E−01   1.61E−01   1   Unchanged Low       O00764   D16cd3   pyridoxal (pyridoxine; vitamin B6   160.2678   140   104.6915   135.073   −6.14E−01   −1.92E−01   1   Unchanged Low       Q9Y6Q5   P13cd5   adaptor-related protein complex   149.3929   107   104.7705   120.3004   −5.12E−01   −4.85E−01   1   Unchanged Low       O95350   G04cd5   Homer; neuronal immediate early   137.2833   126   104.7829   122.6314   −3.90E−01   −1.26E−01   1   Unchanged Low       P49748   C13ab2   acyl-Coenzyme A dehydrogenase   121.151   141   104.7897   122.4441   −2.09E−01   2.23E−01   1   Unchanged Low       P08100   O24cd1   rhodopsin (opsin 2; rod pigment)   125.3282   116   104.8101   115.4338   −2.58E−01   −1.10E−01   1   Unchanged Low       Q15477   F24cd2   superkiller virallcidic activity 2-like   102.5551   186   104.8138   131.0636   3.14E−02   8.58E−01   1   Unchanged Low       O43520   I17cd1   ATPase; Class I; type 8B; memb             199.1157   91.5   104.8252   131.8072   −9.26E−01   −1.12E+00   1   Unchanged Low       O13039   P02ef4   ATP-binding cassette; sub-family   175.7841   80.5   104.8585   120.383   −7.45E−01   −1.13E+00   1   Unchanged Low       O15291   L12cd1   solute carrier family 7 (cationic a             276.3689   176   104.904   185.7368   −1.40E+00   −6.52E−01   1   Unchanged Low       Q9NR71   L23gh4   mitochondrial ceramidase   108.9644   152   104.9361   122.091   −5.43E−02   4.84E−01   1   Unchanged Low       O60884   H10cd4   DnaJ (Has40) homolog; subfamily   221.9835   239   104.9441   188.5763   −1.08E+00   1.05E−01   1   Unchanged Low       Q9BYE0   J17gh8   hairy and enhancer of split 7 (Dr             128.0255   108   104.9542   113.8134   −2.87E−01   −2.39E−01   1   Unchanged Low       Q9Y272   L01ef2   RAS; dexamethasone-induced 1   101.2051   166   104.9825   124.0354   5.29E−02   7.13E−01   1   Unchanged Low       Q9BUR5   M13gh8   hyphothetical protein MGC4825   78.2636   239   105.0137   140.65   4.24E−01   1.61E+00   1   Unchanged Low       O60859   A13cd7   neuropathy target esterase   123.9707   117   105.029   115.3513   −2.39E−01   −8.28E−02   1   Unchanged Low       Q9GZU1   A20gh4   mucolipin 1   85.32301   243   105.1039   144.4516   3.01E−01   1.51E+00   1   Unchanged Low       P19878   B15ab6   neutrophil cytosolic factor 2 (65id   310.5103   515   105.1041   310.3051   −1.56E+00   7.31E−01   1   Unchanged Low       Q13277   K12cd2   syntaxin 3A   118.5375   185   105.2511   136.1937   −1.72E−01   6.41E−01   1   Unchanged Low           B04gh8   reserved   130.849   124   105.2594   120.0361   −3.14E−01   −7.76E−02   1   Unchanged Low       P32456   N18ab4   guanyiate binding protein 2; inter   109.3786   142   105.2611   118.8515   −5.54E−02   3.76E−01   1   Unchanged Low       Q9H4M9   E01cd7   EH-domain containing 1   149.0051   151   105.3893   134.9992   −5.00E−01   1.54E−02   1   Unchanged Low       Q9BTX7   O19gh6   chromosome 20 open reading fra             115.9099   157   105.4128   126.203   −1.37E−01   4.40E−01   1   Unchanged Low       Q9NVN2   M02gh3   solute carrier family 4 (anion exc             123.8178   114   105.466   114.476   −2.31E−01   −1.17E−01   1   Unchanged Low       Q99758   A17ab2   ATP-binding cassette; sub-family   238.456   145   105.5504   163.1362   −1.18E+00   −7.14E−01   1   Unchanged Low       P43694   B06ef6   GATA binding protein 4   107.7539   161   105.5891   124.6996   −2.93E−02   5.77E−01   1   Unchanged Low       Q13825   C07ab3   AU RNA binding protein/enoyi-C             123.4494   140   105.6272   123.0884   −2.25E−01   1.83E−01   1   Unchanged Low       Q92550   L23ef3   ring finger protein 10   197.4603   112   105.7052   138.2365   −9.02E−01   −8.24E−01   1   Unchanged Low       Q9UJS0   C12ef3   solute carrier family 25; member   119.1806   139   105.8216   121.1782   −1.72E−01   2.17E−01   1   Unchanged Low       Q99611   O05ef3   seleriophosphate synthetase 2   168.8742   128   105.8955   134.292   −6.73E−01   −3.99E−01   1   Unchanged Low       P17275   F08ab6             un B proto-oncogene   135.9478   94.9   105.9141   112.2701   −3.60E−01   −5.18E−01   1   Unchanged Low       Q13477   B09cd4   mucosal vascular addressin cell   127.8352   110   105.9239   114.7415   −2.71E−01   −2.11E−01   1   Unchanged Low       P50991   H09cd6   chaperonin containing TCP1; su             181.4396   148   106.0337   138.5813   −6.06E−01   −1.23E−01   1   Unchanged Low       P35548   K11ab7   msh homeo box homolog 2 (Dro             182.4309   124   106.057   137.5011   −7.83E−01   −5.57E−01   1   Unchanged Low       P11309   M14ab8   pim-1 oncogene   136.3951   99   106.0757   113.8227   −3.63E−01   −4.62E−01   1   Unchanged Low       O75570   A03cd5   mitochondrial transiational relea             128.9238   118   106.1208   117.597   −2.81E−01   −1.31E−01   1   Unchanged Low       Q9NY61   O01ef3   apoplosis antagonizing transcrip             120.3605   124   106.1404   116.8527   −1.81E−01   4.36E−02   1   Unchanged Low       Q9BTY8   D01gh7   hypothetical protein MGC4342   139.5304   92.9   106.2168   112.876   −3.94E−01   −5.87E−01   1   Unchanged Low       Q9NWS2   F09gh2   hypothetical protein FLJ20640   183.0823   140   106.2384   143.0354   −7.85E−01   −3.89E−01   1   Unchanged Low       O00180   H06ab6   potassium channel; subfamily K;   129.4915   122   106.2703   119.3824   −2.85E−01   −8.14E−02   1   Unchanged Low       O15382   I05ab3   branched chain aminotransferas             136.8391   95.5   106.3058   112.8868   −3.64E−01   −5.19E−01   1   Unchanged Low       Q9Y2Z1   D05ef2   CGI-01 protein   156.4563   196   106.3369   153.067   −5.57E−01   3.28E−01   1   Unchanged Low       Q9Y315   E18ef2   CGI-26 protein   135.7793   111   106.6662   117.8557   −3.48E−01   −2.89E−01   1   Unchanged Low       Q9Y592   P20ef1   NY-REN-58 antigen   118.6541   121   106.7049   115.3792   −1.53E−01   2.56E−02   1   Unchanged Low       Q9NYT0   D20ef3   pleckstrin 2 (mouse) homolog   114.999   153   106.7508   124.8364   −1.07E−01   4.10E−01   1   Unchanged Low       Q9Y343   M10ef4   SBBI31 protein   123.0625   120   106.8362   116.6438   −2.04E−01   −3.60E−02   1   Unchanged Low       Q9BVI4   G09gh8   hypothetical protein MGC3162   140.5988   123   106.8523   123.6298   −3.96E−01   −1.88E−01   1   Unchanged Low       P30622   B20cd1   restin (Reed-Steinberg cell-expr             116.8074   136   107.0013   119.7985   −1.27E−01   2.15E−01   1   Unchanged Low       Q08345   F08ef5   discoidin domain receptor family;   266.6468   264   107.136   212.6497   −1.32E+00   −1.35E−02   1   Unchanged Low       P33176   C16ab7   kinesin family member 5B   123.5679   113   107.2314   114.5075   −2.05E−01   −1.33E−01   1   Unchanged Low       P55273   D14ab4   cyclin-dependent kinase inhibitor   99.64375   174   107.4234   126.8971   1.08E−01   8.01E−01   1   Unchanged Low       Q9NW92   E10gh3   hypothetical protein FLJ10209   177.1237   166   107.454   150.3287   −7.21E−01   −9.00E−02   1   Unchanged Low       Q9NZC3   K03ef3   membrane interacting protein of              105.8303   152   107.465   121.8015   2.21E−02   5.23E−01   1   Unchanged Low       P15172   M19ab7   myogenic factor 3   132.7839   110   107.4694   116.7347   −3.05E−01   −2.72E−01   1   Unchanged Low       P27144   A06ab2   adenylate kinase 3   118.5733   124   107.5998   116.7128   −1.40E−01   6.42E−02   1   Unchanged Low       O60508   A06ef2   pre-mRNA splicing factor 17   150.1968   130   107.6187   129.259   −4.81E−01   −2.09E−01   1   Unchanged Low       Q14012   B08cd3   calcium/calmodulin-dependent p             113.9231   135   107.6204   118.8965   −8.21E−02   2.46E−01   1   Unchanged Low       P98179   G12cd1   RAN binding motif protein 3   140.1356   93.2   107.7553   113.6891   −3.79E−01   −5.89E−01   1   Unchanged Low       Q13223   E10ab5   BRF1 homolog; subunit of RNA              150.0469   115   107.7567   124.3969   −4.78E−01   −3.79E−01   1   Unchanged Low       P55198   N09ab7   myeloid/lymphoid or mixed-linear             180.7113   122   107.7762   136.7788   −7.46E−01   −5.69E−01   1   Unchanged Low       P46459   G02ef1   N-ethylmaleimide-sensitive facto             138.9363   95.7   107.8044   114.1635   −3.66E−01   −5.37E−01   1   Unchanged Low       P34969   I21ef1   5-hydroxytryptamine (serotonin)              218.7666   181   107.8181   169.3507   −1.02E+00   −2.70E−01   1   Unchanged Low       Q14667   K02gh1   KIAA0100 gene product   105.9471   222   107.8612   145.1883   2.58E−02   1.07E+00   1   Unchanged Low       Q92830   J14cd8   GCN5 general control of amino-             129.4527   106   107.863   114.5758   −2.63E−01   −2.83E−01   1   Unchanged Low           P14cd2   RNA binding motif protein; Y chr             112.3917   153   107.9125   124.4395   −5.87E−02   4.45E−01   1   Unchanged Low       O43252   J01cd5   3′-phosphoadenosine 5′-phosph             194.4946   188   107.9154   163.4169   −8.50E−01   −5.02E−02   1   Unchanged Low       Q9NS93   G09ef3   seven transmembrane protein T             138.0932   237   107.9483   160.8518   −3.55E−01   7.76E−01   1   Unchanged Low       O60618   E20ab8   core-binding factor; runt domain;   489.0924   48.1   107.9969   215.0608   −2.81E+00   −3.35E+00   1   Unchanged Low       P02261   D19cd4   H2A histone family; member C   145.0821   84.1   108.023   112.4051   −4.26E−01   −7.87E−01   1   Unchanged Low       Q14701   F18ef7   DNA cross-link repair 1A (PSO2   119.2486   307   108.208   178.2467   −1.40E−01   1.37E+00   1   Unchanged Low       Q9P025   A04ef8   HSPC135 protein   160.3109   135   108.2493   134.6437   −5.67E−01   −2.44E−01   1   Unchanged Low       P06702   O12ef7   S100 calcium binding protein A9   144.7319   163   108.2576   138.5985   −4.19E−01   1.70E−01   1   Unchanged Low       Q9Y5Q9   P05cd7   general transcription factor IIIC;              138.644   220   108.3524   155.7377   −3.56E−01   6.68E−01   1   Unchanged Low       p19075   O20cd2   transmembrane 4 superfamily m             129.5468   103   108.6355   113.7491   −2.54E−01   −3.30E−01   1   Unchanged Low       O60905   B16cd4   sperm associated antigen 9   110.7683   139   108.6913   119.4574   −2.73E−02   3.27E−01   1   Unchanged Low       Q13322   F24ef5   growth factor receptor-bound pro   120.8593   115   106.7182   114.7351   −1.53E−01   −7.64E−02   1   Unchanged Low       Q9UQ09   L01gh1   KIAA0470 gene product   190.3667   103   108.9005   134.0152   −8.06E−01   −8.89E−01   1   Unchanged Low       P57053   J20gh6   H2B histone family; member S   113.6057   199   108.9238   140.5964   −6.07E−02   8.11E−01   1   Unchanged Low       Q92878   J03ab8   kallikrein 6 (neurosin; zyme)   197.2979   130   108.9308   145.5667   −8.57E−01   −5.97E−01   1   Unchanged Low       P09960   F21ab6   leukotriene A4 hydrolase   96.36818   185   109.0526   130.2822   1.78E−01   9.44E−01   1   Unchanged Low       Q9HBH1   O02gh5   peptide deformylase-like protein   138.0653   91   109.0612   112.7249   −3.40E−01   −6.01E−01   1   Unchanged Low       P55082   L15ab7   microfibrillar-associated protein              121.4467   124   109.134   118.1545   −1.54E−01   2.87E−02   1   Unchanged Low       Q9NVH6   B01gh3   trimethyllysine hydroxylase; epsil   174.7559   81.6   109.1442   121.828   −6.79E−01   −1.10E+00   1   Unchanged Low       O95249   K10cd5   golgi SNAP receptor complex m             107.5878   143   109.1657   119.983   2.10E−02   4.12E−01   1   Unchanged Low       Q13891   M15ab8   basic transcription factor 3; like 2   126.6543   120   109.1942   118.5076   −2.14E−01   −8.18E−02   1   Unchanged Low       Q9BZM5   H05gh7   UL16 binding protein 2   133.6731   245   109.2193   162.5485   −2.91E−01   8.73E−01   1   Unchanged Low       O94913   O20ef2   PCF11p homolog   205.6752   80.3   109.2409   131.7517   −9.13E−01   −1.36E+00   1   Unchanged Low       Q12987   E03ef4   acidic 82 kDa protein mRNA   132.1136   117   109.4318   119.3623   −2.72E−01   −1.81E−01   1   Unchanged Low       Q92499   D05ab5   DEAD/H (Asp-Glu-Ala-Asp/His)              176.6983   124   109.4356   136.6656   −6.91E−01   −5.13E−01   1   Unchanged Low       Q13688   B19ab2   alkylation repair; alkB homolog   105.5169   143   109.4797   119.4385   5.32E−02   4.42E−01   1   Unchanged Low       P43250   I08ab4   G protein-coupled receptor kinas   120.3579   113   109.4844   114.2814   −1.37E−01   −9.10E−02   1   Unchanged Low       Q9UMX0   L03ef4   ubiquilin 1   122.0111   141   109.5522   124.0398   −1.55E−01   2.04E−01   1   Unchanged Low       O94905   G12cd7   chromosome 8 open reading fra             127.8659   107   109.6202   114.8261   −2.22E−01   −2.57E−01   1   Unchanged Low       Q9UHK0   K01cd8   nuclear fragile X mental retardat             157.4757   87.6   109.6296   118.2396   −5.22E−01   −8.46E−01   1   Unchanged Low       P25189   D01ab6   myelin protein zero (Charcot-Ma             110.5502   132   109.6859   117.3068   −1.13E−02   2.52E−01   1   Unchanged Low       Q10567   M11ab2   adaptor-related protein complex   208.9283   187   109.8204   168.4738   −9.28E−01   −1.62E−01   1   Unchanged Low       O15230   D18cd8   laminin; alpha 5   11.864   141   109.8469   120.9363   −2.63E−02   3.35E−01   1   Unchanged Low       P52294   J10ab6   karyopherin alpha 1 (Importin alc   178.7513   169   109.9831   152.7331   −7.01E−01   −7.70E−02   1   Unchanged Low       O60668   M03cd2   TAF2 RNA polymerase II; TATA   123.6244   111   110.0571   114.8794   −1.68E−01   −1.56E−01   1   Unchanged Low       P11686   J02cd1   surfactant; pulmonary-associate             136.0267   117   110.0847   121.0017   −3.05E−01   −2.19E−01   1   Unchanged Low       Q9NWB6   P03gh2   hypothetical protein FLJ10154   174.7789   75   110.1306   119.9579   −6.66E−01   −1.22E+00   1   Unchanged Low       Q9H028   E22gh8   histone deacetylase 10   107.5034   138   110.1585   118.4626   3.52E−02   3.57E−01   1   Unchanged Low       Q9UMZ2   O22cd7   AP1 gamma subunit binding prot   120.2821   119   110.2219   116.5628   −1.26E−01   −1.32E−02   1   Unchanged Low       P24752   C15ab2   acetyl-Coenzyme A acetyltransfe   216.1409   114   110.2562   146.8035   −9.71E−01   −9.23E−01   1   Unchanged Low       P11230   B06ab3   chollnergic receptor; nicotinic; be   106.1774   151   110.2999   122.607   5.50E−02   5.11E−01   1   Unchanged Low       O14977   O18ef2   ornithine decarboxylase antizym             119.9172   129   110.3   119.7626   −1.21E−01   1.06E−01   1   Unchanged Low           E15ef5   T cell receptor beta locus   139.7091   844   110.3287   364.6946   −3.41E−01   2.59E+00   1   Unchanged Low       P56937   N06ef2   hydroxysteroid (17-beta) dehydr             227.1137   74.5   110.3428   137.3284   −1.04E+00   −1.61E+00   1   Unchanged Low       O75299   B21ab7   kinesin family member C3   113.15   128   110.3535   117.1803   −3.61E−02   1.78E−01   1   Unchanged Low       P16219   C09ab2   acyl-Coenzyme A dehydrogenase   109.4688   136   110.3636   118.69   1.17E−02   3.16E−01   1   Unchanged Low       Q9NZ48   J20gh3   uncharacterized hematopoletic s             112.5665   189   110.3995   137.2614   −2.80E−02   7.46E−01   1   Unchanged Low       Q9P163   L10gh4   hypothetical protein PRO2521   101.1317   159   110.4184   123.4514   1.27E−01   6.51E−01   1   Unchanged Low       Q9BVT8   I07gh8   hypothetical protein MGC5442   135.5302   137   110.5044   127.7419   −2.95E−01   1.76E−02   1   Unchanged Low       Q99933   E02ef6   BCL2-associated athanogene   119.7332   115   110.533   115.0469   −1.15E−01   −5.98E−02   1   Unchanged Low       O14645   M12cd3   dynein; axonernal; light intermed             164.1806   207   110.5493   160.4204   −5.71E−01   3.31E−01   1   Unchanged Low       Q9BRR9   E01gh8   Rho GTPase activating protein 9   120.3646   115   110.5606   115.1711   −1.23E−01   −7.10E−02   1   Unchanged Low       Q9Y3E7   J19ef2   CGI-149 protein   158.4397   202   110.6074   157.1807   −5.18E−01   3.54E−01   1   Unchanged Low       P46976   C09ab6   glycogenin   127.6502   117   110.6815   118.5706   −2.06E−01   −1.21E−01   1   Unchanged Low       O75928   C01cd5   Protein Inhibitor of activated STA   98.84393   173   110.7286   127.4786   1.64E−01   8.06E−01   1   Unchanged Low       Q9NX63   I18gh2   hypothetical protein FLJ20420   123.3725   159   110.8068   131.146   −1.55E−01   3.68E−01   1   Unchanged Low       Q9UBS0   I20cd2   ribosomal protein S6 kinase; 70 k   186.953   155   110.8188   150.9199   −7.54E−01   −2.71E−01   1   Unchanged Low       Q15185   F18cd6   unactive progesterone receptor;             169.4269   72.3   110.8534   117.54   −6.12E−01   −1.23E+00   1   Unchanged Low       O60516   J18cd3   eukaryotic translation Initiation fa   104.3739   147   110.9085   120.8526   8.76E−02   4.97E−01   1   Unchanged Low       Q16651   J01ab8   protease; serine; B (prostasin)   334.0498   125   110.9253   190.1399   −1.59E+00   −1.41E+00   1   Unchanged Low       P48788   E22cd2   troponin I; skeletal; fast   121.3602   110   110.9357   114.1376   −1.30E−01   −1.40E−01   1   Unchanged Low       Q01968   N06ab7   oculocerebrorenal syndrome of L   169.0079   95.9   110.9507   125.3025   −6.07E−01   −8.17E−01   1   Unchanged Low       Q9H6Z6   L11gh7   hypothetical protein FLJ21628   115.1546   126   111.0337   117.2667   −5.26E−02   1.25E−01   1   Unchanged Low       Q9NQ55   B01gh4   peter pan homolog ( Drosophila )   122.449   120   111.0627   117.676   −1.41E−01   −3.50E−02   1   Unchanged Low       O95359   A24gh1   transforming; acidic colled-coil c             108.2194   139   111.0999   119.4624   3.79E−02   3.62E−01   1   Unchanged Low       P01189   I15ab8   proopiomelanocortin (adrenocort   145.0634   90.4   111.1389   115.5442   −3.84E−01   −6.82E−01   1   Unchanged Low       Q9Y525   G13cd8   v-maf musculoaponeurotic fibros             119.023   141   111.1934   123.6546   −9.82E−02   2.42E−01   1   Unchanged Low       Q9UHC9   L09cd8   NPC1 (Niemann-Pick disease; ty   107.7403   138   111.3741   118.9021   4.79E−02   3.53E−01   1   Unchanged Low       Q9HBT2   P14gh7   hypothetical protein PP1057   147.5097   98   111.4385   118.9743   −4.05E−01   −5.90E−01   1   Unchanged Low       O00219   M22ef1   hyaluronan synthase 3   224.5087   89   111.4539   141.641   −1.01E+00   −1.34E+00   1   Unchanged Low       P22735   M16cd1   transglutaminase 1 (K polypeptid   136.8808   91   111.5589   113.1407   −2.95E−01   −5.89E−01   1   Unchanged Low       O15388   A11ab4   stalic acid binding Ig-like lectin 6   105.2847   147   111.6016   121.3043   8.41E−02   4.82E−01   1   Unchanged Low       O95389   J01cd4   WNT1 inducible signalling pathw             134.8825   94   111.6123   113.4959   −2.73E−01   −5.21E−01   1   Unchanged Low       Q06190   D21ab8   protein phosphatase 2 (formerity:   134.6973   102   111.6192   116.2494   −2.69E−01   −3.98E−01   1   Unchanged Low       P50226   C03cd3   sulfotransferase family; cytosolic   147.6874   101   111.8328   120.0792   −4.01E−01   −5.52E−01   1   Unchanged Low       Q16632   N10ab5   general transcription factor IIIC;              120.7982   116   111.85   116.1383   −1.11E−01   −6.14E−02   1   Unchanged Low       P54762   A24ef7   EohB1   107.3397   168   111.8669   129.1191   5.96E−02   6.48E−01   1   Unchanged Low       Q15269   E15cd1   PWP2 periodic tryptophan protei   125.0688   107   111.8713   114.654   −1.61E−01   −2.25E−01   1   Unchanged Low       O14495   H10cd3   phosphatidic acid phosphatase              120.761   109   111.9087   113.9808   −1.10E−01   −1.44E−01   1   Unchanged Low       Q9P0U0   N24ef3   PC326 protein   152.5639   101   111.9543   121.9267   −4.47E−01   −5.91E−01   1   Unchanged Low       P50120   J02ab8   retinol binding protein 2; cellular   231.806   217   111.9639   187.0028   −1.05E+00   −9.36E−02   1   Unchanged Low       Q9UHR0   D08gh1   G protein-coupled receptor kinas   111.83   151   111.9778   124.9147   1.91E−03   4.33E−01   1   Unchanged Low       Q13977   A12ef1   cerebellar degeneration-related              105.2052   180   112.0477   132.4319   9.09E−02   7.75E−01   1   Unchanged Low       P51692   C18cd8   signal transducer and activator o   126.7779   100   112.0645   112.9412   −1.78E−01   −3.43E−01   1   Unchanged Low       P51164   N12ab2   ATPase; H+/K+ exchanging; bet             136.4695   112   112.2007   120.3347   −2.82E−01   −2.81E−01   1   Unchanged Low       Q9NXH3   C02gh2   protein phosphatase 1; regulator   113.3081   127   112.2521   117.6836   −1.35E−01   1.70E−01   1   Unchanged Low           C04gh7   ER to nucleus signalling 2   112.9203   125   112.2701   116.8658   −8.33E−03   1.51E−01   1   Unchanged Low       P16435   G16ef6   P450 (cytochrome) oxidoreducta             110.2003   132   112.2899   118.227   2.71E−02   2.62E−01   1   Unchanged Low           E05gh6   hypothetical protein MGC5338   116.1511   137   112.3522   121.7814   −4.80E−02   2.36E−01   1   Unchanged Low       Q02080   L03ab7   MADS box transcription enhance   138.6124   100   112.3745   117.0502   −3.03E−01   −4.69E−01   1   Unchanged Low       Q15334   J06ab7   lethal giant larvae homolog 1 (Dr   123.3076   110   112.3893   115.3049   −1.34E−01   −1.62E−01   1   Unchanged Low       P10636   J13ab7   microtubule-associated protein              115.8818   142   112.4092   123.46   −4.39E−02   2.94E−01   1   Unchanged Low       Q9Y4J6   A01gh2   zinc finger protein 6 (CMPX1)   138.8767   102   112.4376   117.8247   −3.05E−01   −4.43E−01   1   Unchanged Low       Q9UHY7   P18gh4   E-1 enzyme   108.9217   134   112.5485   118.5336   4.73E−02   3.00E−01   1   Unchanged Low       Q14147   K04gh1   DEAD/H (Asp-Glu-Ala-Asp-/His)              117.5358   119   112.7866   116.4348   −5.95E−02   1.76E−02   1   Unchanged Low       O95880   N06gh4   KIAA1513 protein   168.2097   104   112.9115   128.5046   −5.75E−01   −6.88E−01   1   Unchanged Low       Q15013   J23ef3   gene predicted from cDNA with a   104.556   198   113.0807   138.5918   1.13E−01   9.22E−01   1   Unchanged Low       Q9P1E2   E01gh4   hypothetical protein PRO2219   138.6039   107   113.1066   119.6869   −2.93E−01   −3.69E−01   1   Unchanged Low       P07203   H23ef1   glutathione peroxidase 1   120.5127   114   113.1788   115.8519   −9.06E−02   −8.19E−02   1   Unchanged Low       Q13206   M07ab5   DEAD/H (Asp-Glu-Ala-Asp/His)              140.5274   92.5   113.1804   115.4153   −3.12E−01   −6.03E−01   1   Unchanged Low       O15085   L15ef3   Rho guanine nucleotide exchang   121.8405   111   113.2492   115.3055   −1.05E−01   −1.37E−01   1   Unchanged Low       P48426   C07cd1   phosphatidylinositol-4-phosphate   232.9191   163   113.2533   169.6778   −1.04E−00   −5.16E−01   1   Unchanged Low       Q9NRQ2   K20gh4   phospholipid scramblase 4   126.2397   116   113.2849   118.4782   −1.56E−01   −1.23E−01   1   Unchanged Low       O43171   B24cd3   CDC14 cell division cycle 14 hon   126.784   113   113.382   117.8862   −1.61E−01   −1.60E−01   1   Unchanged Low       Q9HB90   M02gh5   Rag C protein   132.9037   136   113.4299   127.5658   −2.29E−01   3.71E−02   1   Unchanged Low       Q9H733   I21gh5   single Ig IL-1R-related molecule   113.5449   137   113.4753   121.334   −8.84E−04   2.71E−01   1   Unchanged Low       P43353   C06ab2   aldehyde dehydrogenase 3 famil   141.7651   101   113.5244   118.734   −3.21E−01   −4.90E−01   1   Unchanged Low       Q15053   G14gh1   KIAA0040 gene product   111.1705   146   113.5775   123.496   3.09E−02   3.91E−01   1   Unchanged Low       P22301   H01ef7   Interleukin 10   174.8595   108   113.5877   132.021   −6.22E−01   −7.00E−01   1   Unchanged Low       Q9BW47   N12gh5   chromosome 20 open reading fr             125.8289   154   113.6231   131.1841   −1.47E−01   2.92E−01   1   Unchanged Low       P21917   M03ab8   dopamine receptor D4   158.6974   151   113.7899   141.2355   −4.80E−01   −6.96E−02   1   Unchanged Low       Q9Y6K5   M19cd1   2′-5′-oligoadenylate synthetase 3   127.2648   142   113.9993   127.6931   −1.59E−01   1.56E−01   1   Unchanged Low       Q9Y2A4   N22cd5   Kruppel-type zinc finger (C2H2)   136.0849   133   114.1396   127.5854   −2.54E−01   −3.82E−02   1   Unchanged Low       Q16880   A16cd3   UDP glycosyltransferase 8 (UDP   112.9309   133   114.1612   119.9407   1.56E−02   2.33E−01   1   Unchanged Low       O95747   D09cd5   oxidative-stress responsive 1   113.39   123   114.2384   116.7318   1.08E−02   1.12E−01   1   Unchanged Low       P25108   L12ef4   G protein-coupled receptor   100.7123   147   114.2482   120.5368   1.82E−01   5.42E−01   1   Unchanged Low           H23ab6   Immunoglbulin superfamily; me             102.6971   145   114.3219   120.6924   1.55E−01   4.98E−01   1   Unchanged Low       P45984   L18ef5   mitogen-activated protein kinase   139.4168   88   114.3405   113.914   −2.86E−01   −6.64E−01   1   Unchanged Low       Q9NPF7   I03ef3   Interleukin 23; alpha subunit p19   98.83593   182   114.4153   131.5891   2.11E−01   8.77E−01   1   Unchanged Low       Q9UH94   L07cd8   prolactin regulatory element bind   140.4102   106   114.4158   120.3231   −2.95E−01   −4.04E−01   1   Unchanged Low       Q16559   F05cd2   T-cell acute lymphocytic leukem             131.4974   111   114.5482   118.9991   −1.99E−01   −2.45E−01   1   Unchanged Low       Q9UGH0   C02cd8   solute carrier family 17 (auion/su   98.73308   158   114.6616   123.6748   2.16E−01   6.75E−01   1   Unchanged Low       Q15544   J13cd2   TAF11 RNA polymerase II; TATA   117.4634   123   114.6792   118.4317   −3.46E−02   6.82E−02   1   Unchanged Low       O00628   N24ab7   peroxisomal biogenesis factor 7   156.16   96.9   114.7281   122.588   −4.45E−01   −6.89E−01   1   Unchanged Low       O43241   F07ab5   golgi autoantigen; golgin subfam   123.9421   104   114.8381   114.422   −1.10E−01   −2.46E−01   1   Unchanged Low       Q9Y6N1   M14ab4   COX11 homolog; cytochrome c c   127.1203   100   114.8993   114.0678   −1.46E−01   −3.44E−01   1   Unchanged Low       Q9UHX5   O01ef4   HT002 protein; hypertension-rela   98.26523   155   114.9242   122.8348   2.26E−01   6.60E−01   1   Unchanged Low       Q01664   A02cd2   transcription factor AP-4 (activati   268.3453   68.7   115.0377   150.0321   −1.22E+00   −2.01E+00   1   Unchanged Low       Q9BUI1   O03gh6   leukocyte receptor cluster (LRC)   112.2417   125   115.039   117.3611   3.55E−02   1.53E−01   1   Unchanged Low       Q9HBL5   M17gh4   AD023 protein   103.9999   137   115.0443   118.5457   1.46E−01   3.93E−01   1   Unchanged Low       Q9NXV2   N08gh2   hypothetical protein FLJ20040   126.6647   147   115.1386   129.6462   −1.38E−01   2.16E−01   1   Unchanged Low       Q15424   D08cd1   scaffold attachment factor B   134.9613   92.7   115.1845   114.2781   −2.29E−01   −5.42E−01   1   Unchanged Low       P26440   F06ab6   Isovaleryl Coenzyme A dehydrog   178.7093   115   115.2412   136.2534   −6.33E−01   −6.38E−01   1   Unchanged Low       O60264   J11cd3   SWI/SNF related; matrix associa   105.7775   132   115.2498   117.7402   1.24E−01   3.22E−01   1   Unchanged Low       Q15286   K07cd7   RAB35; member RAS oncogene   138.2768   183   115.3443   145.6   −2.62E−01   4.06E−01   1   Unchanged Low       Q9UGK0   I10ef4   DIPB protein   303.2745   172   115.4096   196.7868   −1.39E+00   −8.21E−01   1   Unchanged Low       Q92980   J06cd5   putative protein similar to nessy              142.089   181   115.4166   146.2003   −3.00E−01   3.50E−01   1   Unchanged Low       Q99726   M06cd3   solute carrier family 30 (zinc tran   112.8008   121   115.4854   116.3247   3.39E−02   9.75E−02   1   Unchanged Low       P01111   O17ab8   neuroblastoma RAS viral (v-ras)   123.6283   108   115.5932   115.8629   −9.70E−02   −1.80E−01   1   Unchanged Low       Q92574   G13cd3   tuberous scierosis 1   109.8519   128   115.7107   117.8303   7.50E−02   2.20E−01   1   Unchanged Low       P16106   C01gh7   H3 histone family; member I   134.9364   118   115.868   122.8016   −2.20E−01   −1.98E−01   1   Unchanged Low       Q9NWX5   O24gh2   hypothetical protein FLJ20548   118.1581   112   115.9919   115.5043   −2.67E−02   −7.26E−02   1   Unchanged Low       Q9Y687   M05ab3   adaptor-related protein complex              217.8572   170   116.0173   168.0108   −9.09E−01   −3.57E−01   1   Unchanged Low       Q9Y4F1   J04cd5   FERM; RhoGEF (ARHGEF) and   108.6215   130   116.0342   118.0819   9.52E−02   2.55E−01   1   Unchanged Low       Q06710   M14cd3   paired box gene 8   120.1357   129   116.1006   121.7541   −4.93E−02   1.03E−01   1   Unchanged Low       Q9H6N1   J17gh5   hypothetical protein FLJ22056   214.4909   242   116.2509   190.8582   −8.84E−01   1.73E−01   1   Unchanged Low       Q9NSY1   K09gh3   homolog of mouse BMP-2 Inducil   111.9034   123   116.2514   117.0914   5.50E−02   1.38E−01   1   Unchanged Low       Q14106   H20cd6   transducer of ERBB2; 2   117.9634   134   116.2536   122.8358   −2.11E−02   1.87E−01   1   Unchanged Low       Q9UK11   B02ef4   zinc finger protein 223   119.1221   133   116.2873   122.8322   −3.47E−02   1.60E−01   1   Unchanged Low       P08069   O17ef6   insulin-like growth factor 1 recep             106.3434   178   116.3103   133.4883   1.29E−01   7.42E−01   1   Unchanged Low       Q9H6F5   I21gh6   hypothetical protein MGC2574   120.5097   112   116.3129   116.1638   −5.11E−02   −1.10E−01   1   Unchanged Low       Q14373   O04ab3   galactose-1-phosphate uridylyltt             157.7476   231   116.3555   168.3955   −4.39E−01   5.51E−01   1   Unchanged Low       P20393   G04ef5   nuclear receptor subfamily 1; gro   107.1138   138   116.4228   120.571   1.20E−01   3.67E−01   1   Unchanged Low       P36915   O01ab5   guanine nucleotide binding prote   120.9306   111   116.4819   116.2706   −5.41E−02   −1.18E−01   1   Unchanged Low       O95109   G02cd8   chromosome 20 open reading fr             143.5728   103   116.5321   121.0452   −3.01E−01   −4.79E−01   1   Unchanged Low       Q9NVS2   I24gh3   mitochondrial ribosomal protein              117.9573   124   116.6011   119.5497   −1.67E−02   7.31E−02   1   Unchanged Low       Q92950   B08cd6   CUG triplet repeat; RNA binding   109.8876   129   116.7366   118.6125   8.72E−02   2.34E−01   1   Unchanged Low       Q14977   C04ab7   SP110 nuclear body protein   107.0969   158   116.8973   127.3783   1.26E−01   5.62E−01   1   Unchanged Low       P16105   O04gh6   H3 histone family; member A   94.76745   159   116.9796   123.5385   3.04E−01   7.45E−01   1   Unchanged Low       Q9Y3C1   N18ef2   hypothetical protein HSPC111   145.1935   164   117.0185   141.934   −3.11E−01   1.72E−01   1   Unchanged Low       P37287   C11ef1   phosphatidylinositol glycan; clas             132.5354   109   117.2467   119.4716   −1.77E−01   −2.87E−01   1   Unchanged Low       Q9UIG5   G05ef4   SEEK1 protein   102.5149   148   117.279   122.443   1.94E−01   5.25E−01   1   Unchanged Low       Q9UNE2   G15cd6   rabphilin 3A-like (without C2 dorr   110.3023   123   117.2874   117.0111   8.86E−02   1.62E−01   1   Unchanged Low       Q14123   A17cd1   phosphodiesterase 1C; calmodul   121.3078   132   117.3754   123.5304   −4.75E−02   1.21E−01   1   Unchanged Low       Q16206   P03ab2   cytosolic ovarian carcinoma anti             116.5183   157   117.4492   130.1671   1.15E−02   4.26E−01   1   Unchanged Low       Q9NWT1   D21gh2   hypothetical protein FLJ20624   116.0517   116   117.4816   116.4708   1.77E−02   −2.15E−03   1   Unchanged Low       Q12756   C05ab3   axonal transport of synaptic vesi             138.4398   232   117.5489   162.7767   −2.36E−01   7.47E−01   1   Unchanged Low       P28288   B10ab8   ATP-binding cassette; sub-family   140.4464   95.9   117.5959   117.9674   −2.56E−01   −5.51E−01   1   Unchanged Low       P05198   G08ab5   eukaryotic translation initiation fa             115.5074   119   117.6033   117.2266   2.59E−02   3.77E−02   1   Unchanged Low       Q9H0V9   D08gh7   hypothetical protein DKFZp564L             128.832   101   117.6689   115.9248   −1.31E−01   −3.47E−01   1   Unchanged Low       Q92984   M10ef1   interferon-induced protein 35   258.0737   221   117.8182   198.9799   −1.13E+00   −2.23E−01   1   Unchanged Low       O95498   A13cd5   vanin 2   109.7731   123   117.8273   116.8572   1.02E−01   1.64E−01   1   Unchanged Low       Q9H1E1   J01gh8   ribonuclease 7   109.332   131   117.8377   119.4295   1.08E−01   2.62E−01   1   Unchanged Low       Q9NV88   H01gh3   hypothetical protein FLJ10871   108.5849   125   117.8411   117.172   1.18E−01   2.04E−01   1   Unchanged Low       Q9Y310   F06cd6   SnRNP assembly defective 1 ho             119.9305   113   117.8563   117.0556   −2.52E−02   −8.10E−02   1   Unchanged Low       P48382   O06cd1   regulatory factor X; 5 (influences   191.5142   122   118.0773   143.9771   −6.98E−01   −6.47E−01   1   Unchanged Low       P52738   K04cd3   zinc finger protein 140 (clone pH   136.6586   154   118.1501   136.2205   −2.10E−01   1.71E−01   1   Unchanged Low       Q9NRW1   G23ef3   RAB6B; member RAS oncogene   100.578   179   118.1659   132.4668   2.32E−01   8.29E−01   1   Unchanged Low       O15298   A02ab3   basic leucine zipper nuclear fact             266.9887   110   118.2062   165.1797   −1.18E+00   −1.27E+00   1   Unchanged Low       Q9NUN5   D14gh3   hypothetical protein FLJ11240   114.5392   116   118.2691   116.1573   4.62E−02   1.41E−02   1   Unchanged Low       Q07699   L03cd1   sodium channel; voltage-gated;              116.5431   113   118.3239   115.8757   2.19E−02   −4.76E−02   1   Unchanged Low       P27701   F10ab6   kangal 1 (suppression of tumorig   116.2761   108   118.3881   114.2624   2.60E−02   −1.05E−01   1   Unchanged Low       Q9UER5   O02ef3   TNF-induced protein   104.9755   131   118.4653   118.2694   1.74E−01   3.24E−01   1   Unchanged Low       Q8TAC6   I24gh7   chromosome 11 open reading fr             117.4257   138   118.5887   124.5089   1.42E−02   2.28E−01   1   Unchanged Low       Q9NRW9   K16gh4   angiotensin II; type I receptor-as             136.6357   105   118.6777   120.1901   −2.03E−01   −3.76E−01   1   Unchanged Low       O95147   O15cd7   dual specificity phosphatase 14   181.9968   200   118.7007   166.9415   −6.17E−01   1.37E−01   1   Unchanged Low       Q13895   A19ef7   bystin-like   108.0232   124   118.7967   116.9004   1.37E−01   1.98E−01   1   Unchanged Low       P31645   N03ef5   solute carrier family 6 (neurotran             114.6464   189   118.8487   140.7231   5.19E−02   7.19E−01   1   Unchanged Low       P51511   N17ef7   matrix metalloproteinase 15 (me             122.9018   125   118.8609   122.1739   −4.82E−02   2.16E−02   1   Unchanged Low       Q15154   O11cd1   pericentriolar material 1   127.8378   139   118.8759   128.7076   −1.05E−01   1.25E−01   1   Unchanged Low       Q00007   E17ef6   protein phosphatase 2 (formerly;   108.364   123   118.9838   116.7703   1.35E−01   1.82E−01   1   Unchanged Low       P55822   L08cd2   SH3 domain binding glutamic ac             131.7189   133   119.0263   128.0275   −1.46E−01   1.76E−02   1   Unchanged Low       Q14442   L20ab8   phosphatidylinositol glycan; clas             121.0635   114   119.0306   118.0476   −2.44E−02   −8.61E−02   1   Unchanged Low       P54792   L04ab4   dishevelied; dsh homolog 1 (Dro             126.677   113   119.067   119.4338   −8.94E−02   −1.70E−01   1   Unchanged Low       P42336   A03ef6   phosphoinositide-3-kinase; catal             101.0905   143   119.1581   121.01   2.37E−01   4.98E−01   1   Unchanged Low       Q9UMQ3   G15ab3   BarH-like homeobox 2   99.5713   179   119.1741   132.6879   2.59E−01   8.49E−01   1   Unchanged Low       Q9UPY5   M04ef3   solute carrier family 7; (cationic              173.9407   69.5   119.3079   120.9226   −5.44E−01   −1.32E+00   1   Unchanged Low       P19113   H01ef6   histidine decarboxylase   111.9277   119   119.3155   116.6743   9.22E−02   8.57E−02   1   Unchanged Low       O95394   B16ef3   N-acetylglucosamine-phosphate   124.8164   112   119.3184   118.8198   −6.50E−02   −1.52E−01   1   Unchanged Low       P22557   A14ab2   aminolevulinate; delta-; synthase   202.1179   129   119.3857   150.2281   −7.60E−01   −6.46E−01   1   Unchanged Low       Q9Y3A2   G10ef2   CGI-94 protein   108.7497   167   119.4751   131.6512   1.36E−01   6.16E−01   1   Unchanged Low       Q9H5J4   I05gh6   long-chain fatty-acyl elongase   135.0119   87   119.5181   113.8461   −1.76E−01   −6.34E−01   1   Unchanged Low       P16083   E15ab8   NAD(P)H dehydrogenase; quino             154.7986   98.6   119.5724   124.3296   −3.73E−01   −6.50E−01   1   Unchanged Low       Q99819   D02ab2   Rho GDP dissociation inhibitor (             125.7962   106   119.5853   117.2457   −7.30E−02   −2.42E−01   1   Unchanged Low       O75569   F06cd3   protein kinase; interferon-inducib   100.3086   137   119.6257   118.9057   2.54E−01   4.47E−01   1   Unchanged Low       O15038   F12ef7   serine/arginine repetitive matrix              125.19   96.6   119.719   113.8294   −6.45E−02   −3.74E−01   1   Unchanged Low       Q9HBH5   K09gh4   PAN2 protein   102.0601   139   119.7321   120.3437   2.30E−01   4.48E−01   1   Unchanged Low       P41231   C22ab8   purinergic receptor P2Y; G-prote   131.9219   130   119.8105   127.3275   −1.39E−01   −1.84E−02   1   Unchanged Low       O15397   D01cd6   RAN binding protein 8   114.6925   118   119.9197   117.4304   6.43E−02   3.71E−02   1   Unchanged Low       Q9UDY8   C17cd7   mucosa associated lymphoid tiss   114.4769   120   119.9403   118.129   6.73E−02   6.76E−02   1   Unchanged Low       O95819   E22cd5   mitogen-activated protein kinase   92.42403   156   119.956   122.7769   3.76E−01   7.55E−01   1   Unchanged Low       Q12999   J01ef5   sarcoma amplified sequence   114.9397   110   119.9579   114.8641   6.17E−02   −6.74E−02   1   Unchanged Low       P25440   D07cd2   bromodomain containing 2   116.6707   108   120.0152   114.7701   4.08E−02   −1.16E−01   1   Unchanged Low       P20827   H21ef7   ephrin-A1   298.0458   760   120.3333   392.8203   −1.31E+00   1.35E+00   1   Unchanged Low       Q9H652   P20gh8   hypothetical protein MGC4171   129.5733   107   120.4428   118.9065   −1.05E−01   −2.80E−01   1   Unchanged Low       P31483   L20ef4   TIA1 cytotoxic granule-associate   105.4425   129   120.5386   118.2227   1.93E−01   2.87E−01   1   Unchanged Low       Q9BSM8   G15gh8   hypothetical protein MGC10812   148.2279   273   120.573   180.6391   −2.98E−01   8.82E−01   1   Unchanged Low       P36897   F04ef5   transforming growth factor; beta              115.7567   108   120.6724   114.8546   6.00E−02   −9.83E−02   1   Unchanged Low       Q9UMR9   E08ef3   YME1-like 1 ( S. cerevisiae )   256.0314   197   120.7227   191.0958   −1.08E+00   −3.82E−01   1   Unchanged Low       Q92560   G11ab3   BRCA1 associated protein-1 (ubi   101.36   161   120.7575   127.8687   2.53E−01   6.72E−01   1   Unchanged Low       Q9NWU1   D05gh2   hypothetical protein FLJ20604   99.76081   154   120.7609   124.8325   2.76E−01   6.26E−01   1   Unchanged Low       Q92696   N14ab8   Rab geranylgeranyltransferase;              222.7157   272   120.7706   205.3234   −8.83E−01   2.91E−01   1   Unchanged Low       O95236   M24ef3   apolipoprotein L; 3   106.592   130   120.798   119.1528   1.80E−01   2.87E−01   1   Unchanged Low       Q13202   E21ab5   dual specificity phosphatase 8   146.3963   129   120.7987   131.9045   −2.77E−01   −1.88E−01   1   Unchanged Low       P11277   M02cd1   spectrin; beta; erythrocytic (inclu             112.72   114   120.8055   116.0084   9.99E−02   2.26E−02   1   Unchanged Low       O95397   P18ef1   putative glycolipid transfer protei   99.78536   143   120.8708   121.1071   2.77E−01   5.16E−01   1   Unchanged Low       P05423   A20ab3   BN51 (BHK21) temperature sens   131.8122   95.5   120.9201   116.0734   −1.24E−01   −4.65E−01   1   Unchanged Low       Q14338   I17ab6   fucosyltransferase 2 (secretor st             99.71915   181   120.9483   133.9938   2.78E−01   8.63E−01   1   Unchanged Low       Q9BYI8   A22gh8   AIE-75 binding protein protein   90.11911   164   121.0209   125.1864   4.25E−01   8.67E−01   1   Unchanged Low       Q06203   D01ab8   phosphoribosyl pyrophosphate a   216.3154   105   121.029   147.3953   −8.38E−01   −1.04E+00   1   Unchanged Low       Q9NZ33   P10gh4   brain expressed; X-linked 1   113.8613   162   121.0508   132.4428   8.83E−02   5.12E−01   1   Unchanged Low       P04198   O10ab6   histidine-rich glycoprotein   116.1305   116   121.1163   117.5882   6.06E−02   −7.63E−03   1   Unchanged Low       O96029   F03cd7   opioid growth factor receptor   201.3579   93.5   121.2888   138.7174   −7.31E−01   −1.11E+00   1   Unchanged Low       Q01196   I16ab5   runt-related transcription factor 1   441.1217   136   121.3316   232.9078   −1.86E+00   −1.69E+00   1   Unchanged Low       Q9UHL4   J17cd8   dipeptidylpeptidase 7   180.3445   191   121.351   164.207   −5.72E−01   8.23E−02   1   Unchanged Low       P55211   P16ab3   caspase 9; apoptosis-related cys   113.5416   111   121.3742   115.3899   9.62E−02   −2.94E−02   1   Unchanged Low       P21283   A07ab3   ATPase; H+ transporting; lysoso             288.6034   288   121.3828   232.7446   −1.25E+00   −1.78E−03   1   Unchanged Low       O43422   P02ab8   protein-kinase; interferon-inducit   131.8635   100   121.394   117.7416   −1.19E−01   −4.00E−01   1   Unchanged Low       P78406   L01cd3   RAE1 RNA export 1 homolog (S.   147.1192   97.1   121.4625   121.9098   −2.76E−01   −5.99E−01   1   Unchanged Low       P43362   J18ab7   melanoma antigen; family A; 9   99.05783   139   121.5326   119.97   2.95E−01   4.92E−01   1   Unchanged Low       Q9H693   E12gh6   hypothetical protein FLJ22477   171.7699   96.4   121.6097   129.9396   −4.98E−01   −8.33E−01   1   Unchanged Low       Q9UJ83   A11cd8   2-hydroxyphytanoyl-CoA lyase   99.45467   141   121.6399   120.5495   2.91E−01   4.99E−01   1   Unchanged Low       Q05048   I15ab4   cleavage stimulation factor: 3′ pn   124.1609   105   121.6764   117.088   −2.92E−02   −2.36E−01   1   Unchanged Low       P19784   D11ab4   casein kinase 2; alpha prime pol             94.68573   152   121.7819   122.6579   3.63E−01   6.78E−01   1   Unchanged Low       Q9BUX8   D06gh6   homolog of yeast ribosome biog             167.4752   178   121.8214   155.6701   −4.59E−01   8.56E−02   1   Unchanged Low       Q9Y5P6   D23cd8   GDP-mannose pyrophosphoryla             166.4572   89.4   121.8219   125.8828   −4.50E−01   −8.97E−01   1   Unchanged Low       Q9Y3E1   F16af1   hepatoma-derived growth factor:   97.00713   148   121.9163   122.172   3.30E−01   6.05E−01   1   Unchanged Low       P40426   O07cd1   pre-B-cell leukemia transcription   122.6888   94.8   121.9253   113.1427   −9.01E−03   −3.72E−01   1   Unchanged Low       P11217   K01cd1   phosphorylase; glycogen; muscl             314.8041   110   122.008   182.286   −1.37E+00   −1.52E+00   1   Unchanged Low       Q16563   D18cd2   synaptophysin-like protein   97.62823   144   122.0944   121.3173   3.23E−01   5.63E−01   1   Unchanged Low       O95698   L07ab6   Inhibitor of growth family; membe   102.2388   135   122.1358   119.6732   2.57E−01   3.97E−01   1   Unchanged Low       P19447   K24ef6   excision repair cross-complemen   95.41189   148   122.1425   121.7269   3.56E−01   6.30E−01   1   Unchanged Low       Q9UK39   D08cd7   CCR4 carbon catabolite repressi   173.8761   262   122.1589   185.8825   −5.09E−01   5.89E−01   1   Unchanged Low       Q15785   E23cd7   translocase of outer mitochondri             296.8521   144   122.1776   187.6861   −1.28E+00   −1.04E+00   1   Unchanged Low       Q99571   C14ab8   purinergic receptor P2X; ligand-             418.1812   410   122.3053   316.7241   −1.77E+00   −2.96E−02   1   Unchanged Low       Q9BTY2   E24gh8   hypothetical protein MGC1314 si   131.9449   91.5   122.3524   115.258   −1.09E−01   −5.28E−01   1   Unchanged Low       Q9P0P1   D12ef1   hypothetical protein FLJ10769   147.9172   191   122.4861   153.8845   −2.72E−01   3.71E−01   1   Unchanged Low       Q9Y324   P01ef1   CGI-35 protein   129.1118   97   122.5531   116.2093   −7.52E−02   −4.13E−01   1   Unchanged Low       P37286   O17cd3   ubiquitin-conjugating enzyme E2   98.88763   165   122.5669   128.7921   3.10E−01   7.38E−01   1   Unchanged Low       Q00577   O07ef5   purine-rich element binding prot             116.0341   123   122.5705   120.658   7.91E−02   8.84E−02   1   Unchanged Low       O75152   L21gh1   KIAA0663 gene product   101.4464   140   122.5789   121.2139   2.73E−01   4.61E−01   1   Unchanged Low       P23610   H06cd7   coagulation factor VIII-associate             164.911   103   122.5902   130.3149   −4.28E−01   −6.73E−01   1   Unchanged Low       O75436   M20cd5   vacuolar protein sorting 26 (yeas   118.1135   108   122.6522   116.2363   5.44E−02   −1.30E−01   1   Unchanged Low       Q9HA40   B23gh5   hypothetical protein FLJ12287 si   104.6286   126   122.666   117.8494   2.29E−01   2.71E−01   1   Unchanged Low       Q9NX62   I20gh2   hypothetical protein FLJ20421   103.7764   136   122.701   120.7522   2.42E−01   3.88E−01   1   Unchanged Low       O76062   E04cd2   transmembrane 7 superfamily m             301.1903   215   122.7645   212.8749   −1.29E+00   −4.89E−01   1   Unchanged Low       Q16445   H02ab3   gamma-aminobutyric acid (GAB             150.641   87.5   122.7829   120.3177   −2.95E−01   −7.83E−01   1   Unchanged Low       Q08462   G11ef6   adenylate cyclase 2 (brain)   107.541   146   122.8502   125.3933   1.92E−01   4.39E−01   1   Unchanged Low       P78560   A22ef6   CASP2 and RIPK1 domain conta   108.4508   153   122.8627   128.1152   1.80E−01   4.97E−01   1   Unchanged Low       P19634   N17ef5   solute carrier family 9 (sodium/hy   118.9969   99   122.898   113.6214   4.65E−02   −2.66E−01   1   Unchanged Low       P28370   N12cd1   SWI/SNF related; matrix associa   115.471   106   122.9184   114.9572   9.02E−02   −1.17E−01   1   Unchanged Low       Q92503   H06cd1   SEC14-like 1 ( S. cerevisiae )   151.5939   151   122.9424   141.9225   −3.02E−01   −3.46E−03   1   Unchanged Low       Q9UL02   H24ef1   L-kynurenine/alpha-aminoadipat             105.6951   124   123.0487   117.4294   2.19E−01   2.25E−01   1   Unchanged Low       Q9Y5T5   J13cd6   ubiquitin specific protease 16   117.1056   120   123.0646   120.0007   7.16E−02   3.32E−02   1   Unchanged Low           G03gh8   protocadherin 15   153.0978   126   123.1548   134.1729   −3.14E−01   −2.78E−01   1   Unchanged Low       P15848   H02ab2   arylsulfatase B   149.4791   95.6   123.1651   122.7499   −2.79E−01   −6.45E−01   1   Unchanged Low       Q9UP66   P24ab6   low density lipoprotein receptor-             114.2435   124   123.2083   120.4437   1.09E−01   1.17E−01   1   Unchanged Low       O75160   P07gh1   KIAA0672 gene product   121.9398   117   123.2554   120.8501   1.55E−02   −5.53E−02   1   Unchanged Low       P78385   L14ab6   keratin; hair; basic; 3   100.703   135   123.2569   119.6793   2.92E−01   4.24E−01   1   Unchanged Low       O94967   B21ef8   KIAA0893 protein   92.15324   158   123.2707   124.6247   4.20E−01   7.82E−01   1   Unchanged Low       O95719   K01cd5   xenotropic and polytropic retrovir   108.0877   122   123.3497   117.7043   1.91E−01   1.71E−01   1   Unchanged Low       P48147   F09ab8   prolyl endopeptidase   130.0641   129   123.3564   127.6048   −7.64E−02   −7.45E−03   1   Unchanged Low       P20231   B15gh7   tryptase beta 2   106.6865   130   123.4905   119.9323   2.11E−01   2.81E−01   1   Unchanged Low       O95299   G02ab7   NADH dehydrogenase (ubiquino             107.385   129   123.5991   119.8634   2.03E−01   2.60E−01   1   Unchanged Low       O75033   I18gh1   KIAA0445 gene product   121.5196   122   123.624   122.4835   2.48E−02   9.32E−03   1   Unchanged Low       P61668   D03cd4   ubiquitin-conjugating enzyme E2   99.84401   137   123.637   120.3   3.08E−01   4.61E−01   1   Unchanged Low       P28289   E08cd2   tropomodulin   303.877   272   123.6484   233.0271   −1.30E+00   −1.62E−01   1   Unchanged Low       Q15631   O12ef6   translin   173.134   152   123.6887   149.5989   −4.85E−01   −1.88E−01   1   Unchanged Low       P49888   F03cd2   sulfotransferase; estrogen-prefer   122.2586   95.1   123.7564   113.6937   1.76E−02   −3.63E−01   1   Unchanged Low       P51959   O12ef5   cyclin G1   116.6841   102   123.7661   114.0387   8.50E−02   −1.99E−01   1   Unchanged Low       Q9Y5V0   J16ef1   HSPC038 protein   114.0123   179   123.7928   139.0584   1.19E−01   6.54E−01   1   Unchanged Low       P56270   I12ef1   MYC-associated zinc finger prot             248.3395   140   123.8618   170.7774   −1.00E+00   −8.26E−01   1   Unchanged Low       Q9HD23   O11gh4   MRS2-like; magnesium homeost             140.8864   117   123.8621   127.1502   −1.86E−01   −2.72E−01   1   Unchanged Low       P78358   O03ab6   cancer/testis antigen 1   217.9167   137   123.9307   159.681   −8.14E−01   −6.68E−01   1   Unchanged Low       O00327   D24ab2   aryl hydrocarbon receptor nuclea   118.2008   185   123.9698   142.5298   6.87E−02   6.50E−01   1   Unchanged Low       Q9H969   F08gh5   hypothetical protein FLJ12969   89.23821   177   123.0248   130.1172   4.75E−01   9.89E−01   1   Unchanged Low       O15504   F01cd7   nucleoporin-like protein 1   200.4449   124   124.2046   149.5876   −6.90E−01   −6.92E−01   1   Unchanged Low       P35250   I24ef8   replication factor C (activator 1);   111.3418   112   124.3534   115.9922   1.59E−01   1.21E−02   1   Unchanged Low       Q9BXC0   F17gh8   G protein-coupled receptor 81   104.4833   128   124.3568   118.786   2.51E−01   2.87E−01   1   Unchanged Low       O15232   A19ef1   matrilin 3   113.1634   110   124.4317   115.8185   1.37E−01   −4.27E−02   1   Unchanged Low       O76049   L19cd5   spectrin SH3 domain binding pro   171.9625   299   124.5037   198.6303   −4.66E−01   8.00E−01   1   Unchanged Low       Q14145   C21cd8   Kelch-like ECH-associated protei   193.9671   120   124.5928   146.2645   −6.39E−01   −6.90E−01   1   Unchanged Low       P20848   A10cd1   serine (or cysteine) proteinase in   97.77909   161   124.6004   127.9292   3.50E−01   7.23E−01   1   Unchanged Low       Q9P0N6   C19ef3   hypothetical protein HSPC242   112.0065   109   124.6034   115.304   1.54E−01   −3.53E−02   1   Unchanged Low       P05188   E12ab2   alkaline phosphatase; placental              88.50098   164   124.6125   125.869   4.94E−01   8.94E−01   1   Unchanged Low       Q9UBJ4   A01gh5   transposon-derived Buster1 tran             131.0923   97.3   124.7023   117.695   −7.21E−02   −4.30E−01   1   Unchanged Low       Q13876   I24ef7   quiescin Q6   144.3305   109   124.7205   125.9829   −2.11E−01   −4.06E−01   1   Unchanged Low       Q9UBF2   F12cd7   coatomer protein complex; subur   110.1673   115   124.9117   116.849   1.18E−01   6.78E−02   1   Unchanged Low       P43026   I23cd3   growth differentiation factor 5 (ca   101.9864   152   124.9218   126.3658   2.93E−01   5.77E−01   1   Unchanged Low       Q9HD20   E14gh4   CGI-152 protein   111.6731   134   124.9301   123.6472   1.62E−01   2.67E−01   1   Unchanged Low       Q96KK6   P04ab8   RAB2; member RAS oncogene f             119.8171   106   124.9467   116.8445   6.05E−02   −1.80E−01   1   Unchanged Low       P40617   D18ab2   ADP-ribosylation factor-like 4   124.1402   143   125.0573   130.7449   1.06E−02   2.04E−01   1   Unchanged Low       O75651   L12gh2   unc-93 homolog A ( C. elegans )   131.989   128   125.0667   128.2583   −7.77E−02   −4.74E−02   1   Unchanged Low       Q9Y2S1   L04ef1   galanin-related peptide   135.6724   134   125.067   131.4839   −1.17E−01   −2.10E−02   1   Unchanged Low       Q13330   M20ef5   metastasis associated 1   104.9962   118   125.1131   116.0949   2.53E−01   1.71E−01   1   Unchanged Low       Q9Y389   L22gh4   aminoadipate-semialdehyde detr   115.3352   104   125.222   114.7055   1.19E−01   −1.55E−01   1   Unchanged Low       O60513   I03gh1   UDP-Gal:betaGlcNAc beta 1; 4-             113.705   106   125.2504   115.0129   1.40E−01   −1.00E−01   1   Unchanged Low       O00212   C15ef6   ras homolog gene family; memb             407.7018   492   125.2682   341.5178   −1.70E+00   2.70E−01   1   Unchanged Low       Q9NXE1   J04gh2   membrane-associated nucleic ac   96.25484   146   125.3861   122.4125   3.81E−01   5.97E−01   1   Unchanged Low       O95405   A16cd5   MAD; mothers against decapent             113.9303   223   125.3908   154.2554   1.38E−01   9.72E−01   1   Unchanged Low       P01112   K12ab7   v-Ha-ras Harvey rat sarcoma vir             129.7326   104   125.3947   119.6125   −4.91E−02   −3.23E−01   1   Unchanged Low       O15120   F11cd6   1-acylglycerol-3-phosphate O-ac   264.2959   238   125.4039   209.3705   −1.08E+00   −1.49E−01   1   Unchanged Low       P12645   N10ab3   bone morphogenetic protein 3 (o   107.6548   117   125.4244   116.6372   2.20E−01   1.18E−01   1   Unchanged Low       P50579   I01cd7   methionyl aminopeptidase 2   144.5853   95.1   125.4613   121.7158   −2.05E−01   −6.04E−01   1   Unchanged Low       O14908   K01cd8   regulator of G-protein signalling   204.527   200   125.5241   176.6683   −7.04E−01   −3.26E−02   1   Unchanged Low       Q9HCC6   I17gh4   bHLH factor Hes4   82.07855   213   125.5621   140.2118   6.13E−01   1.38E+00   1   Unchanged Low       Q15737   E23gh1   suppressor of Ty 6 homolog (S.              112.2771   140   125.5917   125.8246   1.62E−01   3.14E−01   1   Unchanged Low       Q9Y519   A17cd8   chromosome 22 open reading fra   100.4037   131   125.6586   119.1056   3.24E−01   3.87E−01   1   Unchanged Low       Q9Y5J0   J01ef2   mitochondrial ribosomal protein              117.4353   107   125.8555   116.7986   9.99E−02   −1.33E−01   1   Unchanged Low       P51687   O16cd1   sulfite oxidase   105.2314   128   125.9497   119.5637   2.59E−01   2.77E−01   1   Unchanged Low       P51178   A13ef6   phospholipase C; delta 1   126.4221   162   126.0345   138.0904   −4.43E−03   3.56E−01   1   Unchanged Low       Q9H8J6   H23gh5   NDRG family member 3   121.7115   198   126.048   148.4766   5.05E−02   7.00E−01   1   Unchanged Low       O95900   B20ef8   hypothetical protein CLONE2492   165.6404   257   126.0637   182.738   −3.94E−01   6.31E−01   1   Unchanged Low       Q9Y6N3   B01cd5   chloride channel; calcium activat   99.89597   135   126.1695   120.3564   3.37E−01   4.35E−01   1   Unchanged Low       Q07869   C21cd1   peroxisome proliferative activate             120.1031   112   126.2127   119.4872   7.16E−02   −9.89E−02   1   Unchanged Low       Q9Y333   I07gh4   chromosome 6 open reading frar   109.0761   114   126.2563   116.4501   2.11E−01   6.39E−02   1   Unchanged Low       Q9NPD1   L06gh2   G protein-coupled receptor 85   206.0578   285   126.2683   205.7432   −7.07E−01   4.67E−01   1   Unchanged Low       Q15928   K06cd3   zinc finger protein 141 (clone pH   101.1559   188   126.2732   138.6304   3.20E−01   8.98E−01   1   Unchanged Low       O43826   I04ab4   glucose-6-phosphatase; transpo             229.7084   111   126.3113   155.5451   −8.63E−01   −1.05E+00   1   Unchanged Low       Q9NWL0   J05gh2   hypothetical protein FLJ20758   114.0453   120   126.3891   120.1186   1.48E−01   7.25E−02   1   Unchanged Low       P31629   B04ef6   human immunodeficiency virus t             116.0174   211   126.4284   151.1911   1.24E−01   8.64E−01   1   Unchanged Low       O15530   I10ab8   3-phosphoinositide dependent p             186.1234   193   126.45   168.488   −5.58E−01   5.15E−02   1   Unchanged Low       Q9Y2R5   L21ef4   mitochondrial ribosomal protein              106.3741   136   126.4713   122.8701   2.50E−01   3.52E−01   1   Unchanged Low       Q15208   D01cd7   serine/threonine kinase 3B   158.8765   204   126.5253   163.2891   −3.28E−01   3.64E−01   1   Unchanged Low       Q9UET6   J19gh6   FisJ homolog 1 ( E. coli )   102.5266   120   126.5378   116.4386   3.04E−01   2.30E−01   1   Unchanged Low       Q9H5N0   F15gh5   chromosome 7 open reading frar   102.3349   129   126.5687   119.1911   3.07E−01   3.30E−01   1   Unchanged Low       Q9H019   B22gh4   hypothetical protein RP1-317E23   102.5329   150   126.5974   126.5367   3.04E−01   5.53E−01   1   Unchanged Low       Q9Y673   F05cd8   Alg5;  S. cerevisiae ; homolog of   100.2543   131   126.6884   119.1797   3.38E−01   3.81E−01   1   Unchanged Low       O75690   M08gh7   UHS KerB   121.3598   150   126.7819   132.5659   6.31E−02   3.01E−01   1   Unchanged Low       Q9NUP6   H22gh2   hypothetical protein FLJ11220   95.908   144   126.8164   122.1684   4.03E−01   5.84E−01   1   Unchanged Low       Q14296   C03cd7   FAST kinase   122.4924   92.9   126.9021   114.1093   5.10E−02   −3.98E−01   1   Unchanged Low       Q9NW55   B20gh2   hypothetical protein FLJ10307   94.73914   141   126.9877   120.8058   4.23E−01   5.70E−01   1   Unchanged Low       O43639   H01cd3   NCK adaptor protein 2   139.9609   79.6   127.0293   115.5457   −1.40E−01   −8.13E−01   1   Unchanged Low       P17544   L08ab2   activating transcription factor 7   108.5839   112   127.0848   115.9726   2.27E−01   4.79E−02   1   Unchanged Low       O75911   M01cd5   short-chain dehydrogenase/redu             156.3658   173   127.1125   152.0313   −2.99E−01   1.43E−01   1   Unchanged Low       Q06430   K15ef3   glucosaminyl (N-acetyl) transfera   94.56995   139   127.1541   120.315   4.27E−01   5.58E−01   1   Unchanged Low       Q13769   D10cd3   chromosome 22 open reading fra   122.7812   121   127.1547   123.5081   5.05E−02   −2.60E−02   1   Unchanged Low       Q9H864   J14gh5   hypothetical protein FLJ11021 sl   97.58044   142   127.1909   122.387   3.82E−01   5.45E−01   1   Unchanged Low       O95500   F06cd7   claudin 14   183.0294   181   127.2815   163.6478   −5.24E−01   −1.90E−02   1   Unchanged Low       P14222   P02cd2   perforin 1 (pore forming protein)   99.11893   135   127.3674   120.5243   3.62E−01   4.47E−01   1   Unchanged Low       Q9Y4C8   B06ef2   KIAA0682 gene product   105.4769   146   127.3803   126.2296   2.72E−01   4.67E−01   1   Unchanged Low       Q9H3H5   M23ab4   dolichyl-phosphate (UDP-N-acet             193.8179   108   127.5134   143.2265   −6.04E−01   −8.39E−01   1   Unchanged Low       Q13433   G05cd8   LIV-1 protein; estrogen regulate             118.096   105   127.6623   116.7563   1.12E−01   −1.76E−01   1   Unchanged Low       Q00059   O07cd2   transcription factor A; mitochond             111.4615   131   127.6629   123.3486   1.96E−01   2.32E−01   1   Unchanged Low       Q15119   I06ab8   pyruvate dehydrogenase kinase;   97.01115   135   127.6675   120.0132   3.96E−01   4.81E−01   1   Unchanged Low       O43791   F03cd3   speckle-type POZ protein   111.349   114   127.7061   117.7111   1.98E−01   3.49E−02   1   Unchanged Low       Q14206   P10cd5   Down syndrome critical region g             119.8147   263   127.7164   170.2393   9.21E−02   1.14E+00   1   Unchanged Low       Q92926   N24cd1   SWI/SNF related; matrix associa             115.147   105   127.7503   116.1179   1.50E−01   −1.27E−01   1   Unchanged Low       Q9P288   G15ef3   BRCA2 and CDKN1A interacting   148.9477   132   127.8623   136.3262   −2.20E−01   −1.72E−01   1   Unchanged Low       Q9NZU5   C16ef4   LIM and cysteine-rich domains 1   164.1438   128   127.9349   139.9549   −3.60E−01   −3.61E−01   1   Unchanged Low       Q13569   O13cd2   thymine-DNA glycosylase   83.16502   172   127.9545   127.6936   6.22E−01   1.05E+00   1   Unchanged Low       P48167   D17ef6   glycine receptor; beta   109.5501   139   127.9738   125.3664   2.24E−01   3.39E−01   1   Unchanged Low       Q9NQR1   I02gh4   PR/SET domain containing prote   154.2185   92.7   128.0258   124.9651   −2.69E−01   −7.35E−01   1   Unchanged Low       O43405   B23ab4   coagulation factor C homolog; cc   103.0764   121   128.1793   117.417   3.14E−01   2.31E−01   1   Unchanged Low       Q9P028   N24ef2   CCR4-NOT transcription comple             104.0341   133   128.2089   121.9053   3.01E−01   3.59E−01   1   Unchanged Low       Q9Y6E8   P04cd7   sirtuin silent mating type informa             109.1684   110   128.2444   115.6628   2.32E−01   5.37E−03   1   Unchanged Low       Q9NV65   H17gh3   hypothetical protein FLJ10901   92.33747   188   128.3243   136.3658   4.75E−01   1.03E+00   1   Unchanged Low       Q9H0R8   M13gh7   GABA(A) receptor-associated pr             122.091   179   128.3386   143.1503   7.20E−02   5.52E−01   1   Unchanged Low       O95817   P02cd4   BCL2-associated athanogene 3   107.1752   114   128.4319   116.5745   2.61E−01   9.05E−02   1   Unchanged Low       P36956   K10cd2   sterol regulatory element binding   140.2284   109   128.532   125.9988   −1.26E−01   −3.60E−01   1   Unchanged Low       P08236   D05ab3   glucuronidase; beta   123.7102   114   128.6103   122.0379   5.60E−02   −1.21E−01   1   Unchanged Low       Q13425   D12cd2   syntrophin; beta 2 (dystrophin-as   106.7241   122   128.6723   119.2218   2.70E−01   1.96E−01   1   Unchanged Low       Q14676   E18gh1   KIAA0170 gene product   93.41288   145   128.7328   122.2375   4.63E−01   6.30E−01   1   Unchanged Low       P16106   O12gh6   H3 histone family; member F   98.02235   136   128.7695   120.7804   3.94E−01   4.68E−01   1   Unchanged Low       Q14773   J03ab6   intercellular adhesion molecule 4   101.85   137   128.8098   122.427   3.39E−01   4.24E−01   1   Unchanged Low       O14736   N19gh4   putative methyltransferase   124.8741   126   128.8151   126.6152   4.48E−02   1.47E−02   1   Unchanged Low       Q9Y297   N21cd4   beta-transducin repeat containin             152.2864   142   128.8641   141.0555   −2.41E−01   −1.01E−01   1   Unchanged Low       Q13585   H16cd4   G protein-coupled receptor 50   121.9424   113   128.8853   121.1757   7.99E−02   −1.14E−01   1   Unchanged Low       O60858   L24cd5   ret finger protein 2   110.1643   110   128.8939   116.2529   2.27E−01   −6.09E−03   1   Unchanged Low       Q9Y2Z6   E06ef2   CGI-07 protein   96.22816   139   128.9272   121.3443   4.22E−01   5.29E−01   1   Unchanged Low       Q9UG66   P16ef7   hypothetical protein DKFZp586G   318.3297   374   128.9795   273.7118   −1.30E+00   2.32E−01   1   Unchanged Low       Q9Y6G5   N17ef2   PTD002 protein   107.7937   141   129.1324   125.8408   2.61E−01   3.83E−01   1   Unchanged Low       P98155   E06cd3   very low density lipoprotein rece             113.1365   104   129.1355   115.483   1.91E−01   −1.19E−01   1   Unchanged Low       Q9NP50   C07gh5   TERA protein   94.63638   199   129.2792   140.8474   4.50E−01   1.07E+00   1   Unchanged Low       P28328   C01ab8   peroxisomal membrane protein 3   321.6292   219   129.3474   223.2274   −1.31E+00   −5.56E−01   1   Unchanged Low       Q969T4   M24cd6   ubiquitin-conjugating enzyme E2   117.2071   100   129.3512   115.6428   1.42E−01   −2.24E−01   1   Unchanged Low       P19827   D18ab6   Inter-alpha (globulin) inhibitor; H             239.4455   186   129.3613   185.0551   −8.88E−01   −3.62E−01   1   Unchanged Low       O15096   M18ab8   phosphatidylinositol 4-kinase; ca   117.2574   115   129.4365   120.4316   1.43E−01   −3.31E−02   1   Unchanged Low       Q9Y5J6   J16cd7   fracture callus 1 homolog (rat)   102.357   127   129.4503   119.4401   3.39E−01   3.06E−01   1   Unchanged Low       Q92889   M24ab4   excision repair cross-complemen   157.5735   97.6   129.5255   128.238   −2.83E−01   −6.91E−01   1   Unchanged Low       P08697   C07ef1   serine (or cysteine) proteinase in   138.5253   136   129.5425   134.8048   −9.67E−02   −2.29E−02   1   Unchanged Low       Q9UBX1   A05cd4   cathepsin F   113.4065   118   129.6557   120.4495   1.93E−01   6.08E−02   1   Unchanged Low       Q9NPI7   D22ef1   hypothetical protein LOC51315   240.5378   171   129.76   180.4148   −8.90E−01   −4.93E−01   1   Unchanged Low       P11586   D14ef7   methylenetetrahydrofolate dehyd   141.2456   106   129.8444   125.7751   −1.21E−01   −4.11E−01   1   Unchanged Low       O96010   J15cd4   LIM domain binding 1   90.9506   155   129.8567   125.1912   5.14E−01   7.67E−01   1   Unchanged Low       Q13188   P13cd2   serine/threonine kinase 3 (STE2             117.4664   135   129.8809   127.4091   1.45E−01   1.99E−01   1   Unchanged Low       Q13845   I21ab3   B-cell CLL/lymphoma 7B   145.9359   88.3   129.9273   121.3988   −1.68E−01   −7.24E−01   1   Unchanged Low       Q9Y5W9   D07cd8   sorting nexin 11   144.6605   198   130.0152   157.7019   −1.54E−01   4.56E−01   1   Unchanged Low       O60539   I02cd7   Ras association (RalGDS/AF-6)              126.8466   102   130.0346   119.7412   3.58E−02   −3.10E−01   1   Unchanged Low       O60885   I02ef3   bromodomain-containing 4   114.9928   98.1   130.1093   114.4111   1.78E−01   −2.29E−01   1   Unchanged Low       Q9H2B0   O16gh5   nucleosome assembly protein 1-             122.5782   147   130.1112   133.1825   8.60E−02   2.61E−01   1   Unchanged Low       P51582   C24ab8   pyrimidinergic receptor P2Y; G-p   116.4263   109   130.158   118.649   1.61E−01   −9.03E−02   1   Unchanged Low       O00585   F08cd1   small inducible cytokine subfamil   168.745   216   130.1849   171.5056   −3.74E−01   3.53E−01   1   Unchanged Low       Q15131   B23ef5   cyclin-dependent kinase (CDC2-             168.6104   108   130.2201   135.7223   −3.73E−01   −6.38E−01   1   Unchanged Low       O75148   F08cd8   cryptochrome 2 (photolyase-like)   86.14249   172   130.27   129.5265   5.97E−01   9.99E−01   1   Unchanged Low       Q15691   G17cd8   microtubule-associated protein;              173.7024   168   130.2758   157.4437   −4.15E−01   −4.51E−02   1   Unchanged Low       Q15779   H21ab8   procollagen (type III) N-endopep             141.4408   133   130.2905   135.0227   −1.18E−01   −8.51E−02   1   Unchanged Low       Q9UHD2   K14cd8   TANK-binding kinase 1   82.31867   172   130.2947   128.1679   6.62E−01   1.06E+00   1   Unchanged Low       Q9NSS3   K15gh3   hypothetical protein DKFZp434E   107.5389   115   130.3095   117.5518   2.77E−01   9.44E−02   1   Unchanged Low       Q13797   I01ef7   integrin; alpha 9   156.9946   85   130.4752   124.1726   −2.67E−01   −8.84E−01   1   Unchanged Low       P46531   M10ef5   Notch homolog 1; translocation-             86.01963   164   130.4897   126.8111   6.01E−01   9.30E−01   1   Unchanged Low       O43262   C01cd6   deleted in lymphocytic leukemia;   76.79463   195   130.4943   134.2594   7.65E−01   1.35E+00   1   Unchanged Low       Q9Y2H6   k12ef8   KIAA0970 protein   170.8655   128   130.5238   142.9858   −3.89E−01   −4.22E−01   1   Unchanged Low       P25788   J11ab8   proteasome (prosome; macropah   258.6025   285   130.5899   224.7239   −9.86E−01   1.40E−01   1   Unchanged Low       Q98QS8   D09gh7   FYVE and coiled-coil domain cor   164.6348   207   130.6451   167.5571   −3.34E−01   3.33E−01   1   Unchanged Low       Q9Y396   J04ef1   elongation of very long chain fatt   162.6431   82.2   130.6722   125.1558   −3.16E−01   −9.85E−01   1   Unchanged Low       Q9P0R7   K06ef2   hypothetical protein LOC51242   126.7302   218   130.6804   158.5209   4.43E−02   7.84E−01   1   Unchanged Low       O15269   F17cd6   serine palmitoyltransferase; long   97.42808   133   130.7429   120.3129   4.24E−01   4.46E−01   1   Unchanged Low       Q9UFX0   B02ef2   calcium binding atopy-related au             233.5089   287   130.8943   217.1357   −8.35E−01   2.98E−01   1   Unchanged Low       Q9H663   F24gh5   likely ortholog of mouse actin-rel             98.1679   128   130.9258   119.1698   4.15E−01   3.87E−01   1   Unchanged Low       O75410   P17cd2   transforming; acidic coiled-coil α   224.1188   133   130.9827   162.703   −7.75E−01   −7.53E−01   1   Unchanged Low       Q9Y5N5   I14cd8   putative N6-DNA-methyltransfera   99.34841   133   131.0924   121.2285   4.00E−01   4.24E−01   1   Unchanged Low       Q9BQ72   F02gh7   hypothetical protein MGC10471   106.3824   115   131.1126   117.4135   3.02E−01   1.09E−01   1   Unchanged Low       Q9Y303   E10ef2   CGI-14 protein   153.5787   101   131.2035   128.5162   −2.27E−01   −6.08E−01   1   Unchanged Low       Q9P005   A22ef8   HSPC159 protein   341.3083   579   131.3146   350.7027   −1.38E+00   7.64E−01   1   Unchanged Low       Q9Y3A1   H19ef2   DKFZP566O084 protein   200.4927   262   131.514   198.1031   −6.08E−01   3.88E−01   1   Unchanged Low       Q15172   C12cd1   protein phosphatase 2; regulator   168.3914   140   131.5524   146.553   −3.56E−01   −2.69E−01   1   Unchanged Low       Q9BV19   I19gn6   hypothetical protein MGC955   96.47316   141   131.6188   122.8739   4.48E−01   5.43E−01   1   Unchanged Low       Q14534   E11cd2   squalene epoxidase   155.5799   71.3   131.8107   119.574   −2.39E−01   −1.13E+00   1   Unchanged Low       Q9BS43   G19gh8   hypothetical protein MGC12435   592.1694   121   131.9022   281.8569   −2.17E+00   −2.29E+00   1   Unchanged Low       P49788   D24ab8   retinoic acid receptor responder              97.19637   135   131.9355   121.3412   4.41E−01   4.73E−01   1   Unchanged Low       Q9UP83   M10cd6   component of oligomeric golgi cc   100.2446   141   131.938   124.3058   3.96E−01   4.89E−01   1   Unchanged Low       Q9Y2X0   N11cd5   thyroid hormone receptor-associ             116.8982   97.9   131.9541   115.5741   1.75E−01   −2.56E−01   1   Unchanged Low       Q9Y3E3   I15ef2   CGI-145 protein   94.76733   132   131.9919   119.5355   4.78E−01   4.76E−01   1   Unchanged Low       O95183   J14cd6   vesicle-associated membrane pr             91.19765   157   132.0539   126.6473   5.34E−01   7.81E−01   1   Unchanged Low       Q13242   N22cd3   splicing factor; arginine/serine-ri             156.0624   141   132.0637   143.0016   −2.41E−01   −1.48E−01   1   Unchanged Low       Q9Y5R5   A06gh1   doublesex and mab-3 related tra             100.8446   162   132.1528   131.5571   3.90E−01   6.81E−01   1   Unchanged Low       P04181   N02ab7   ornithine aminotransferase (gyra             112.3954   106   132.1687   116.724   2.34E−01   −8.99E−02   1   Unchanged Low       Q14254   B15ab4   flotlllin 2   130.1586   154   132.2038   138.6301   2.25E−02   2.38E−01   1   Unchanged Low       Q9Y6E6   P08cd7   sirtuin silent mating type informa             94.40989   136   132.2501   121.0265   4.86E−01   5.31E−01   1   Unchanged Low       Q9H237   D20gh5   porcupine   148.2204   258   132.2656   179.3923   −1.64E−01   7.98E−01   1   Unchanged Low       Q92785   N21cd2   requiern; apoptosis response zin             118.3718   108   132.3893   119.7533   1.61E−01   −1.26E−01   1   Unchanged Low       O95458   N11cd2   tubulin-specific chaperone d   128.9522   100   132.4761   120.4814   3.89E−02   −3.67E−01   1   Unchanged Low       P20749   P23ef6   B-cell CLL/lymphoma 3   264.1174   186   132.484   194.2507   −9.95E−01   −5.05E−01   1   Unchanged Low       Q9H2N8   D24gh7   hypothetical protein GL012   104.3233   160   132.5137   132.1507   3.45E−01   6.14E−01   1   Unchanged Low       Q15020   M08gh1   squamous cell carcinoma antige             117.2757   147   132.5393   132.2727   1.77E−01   3.26E−01   1   Unchanged Low       P42025   O01gh1   ARP1 actin-related protein 1 hon   243.7979   92   132.554   156.1129   −8.79E−01   −1.41E+00   1   Unchanged Low       P98173   I23gh5   2.19 gene   113.0426   116   132.6703   120.727   2.31E−01   4.31E−02   1   Unchanged Low       O95295   C06cd8   SNARE associated protein snapl   324.3312   119   132.6986   192.0882   −1.29E+00   −1.44E+00   1   Unchanged Low       Q9NVA1   F15gh3   chromosome 20 open reading fr             111.7508   100   132.7232   114.8529   2.48E−01   −1.59E−01   1   Unchanged Low       P35573   O03ab2   amylo-1; 6-glucosidase; 4-alpha-   111.9583   106   132.7432   116.8065   2.46E−01   −8.27E−02   1   Unchanged Low       Q13126   K13ab7   methylthioadenosine phosphoryl             202.8169   236   132.9211   190.4847   −6.10E−01   2.17E−01   1   Unchanged Low       P43034   C11ab8   platelet-activating factor acetylhy   106.8174   125   132.987   121.4511   3.16E−01   2.22E−01   1   Unchanged Low       Q01844   E15ab5   Ewing sarcoma breakpoint regio             111.2628   102   133.001   115.5021   2.57E−01   −1.22E−01   1   Unchanged Low       P27482   E18ab6   calmodulin-like 3   114.7017   104   133.018   117.2725   2.14E−01   −1.40E−01   1   Unchanged Low       Q9NUW4   N23gh3   BRIX   223.8591   77.1   133.0208   144.6673   −7.51E−01   −1.54E+00   1   Unchanged Low       P78552   J23ab6   interleukin 13 receptor; alpha 1   118.2476   93.9   133.0765   115.0749   1.70E−01   −3.33E−01   1   Unchanged Low       P51843   O24ab2   nuclear receptor subfamily 0; gr             104.7329   112   133.1401   116.7757   3.46E−01   1.03E−01   1   Unchanged Low       P15822   L23ab5   human immunodeficiency virus              83.26942   160   133.2118   125.3978   6.78E−01   9.40E−01   1   Unchanged Low       Q9BXY9   O13gh8   RALBP1 associated Eps domain   90.84238   140   133.274   121.2561   5.53E−01   6.20E−01   1   Unchanged Low       Q9ULB4   P10ef1   cadherin 9; type 2 (T1-cadherin)   275.2974   137   133.4641   181.8847   −1.04E+00   −1.01E+00   1   Unchanged Low       Q9NZZ7   C08ef8   HSPC171 protein   214.9523   265   133.5412   204.594   −6.87E−01   3.04E−01   1   Unchanged Low       Q02086   C09cd2   Sp2 transcription factor   101.0989   133   133.5465   122.3826   4.02E−01   3.90E−01   1   Unchanged Low       Q9BUV9   H14gh6   DKFZP586J0119 protein   102.1174   119   133.5923   118.2651   3.88E−01   2.22E−01   1   Unchanged Low       Q9UHJ9   A09ef4   FGF receptor activating protein 1   100.7903   121   133.6008   118.5627   4.07E−01   2.67E−01   1   Unchanged Low       Q16401   E11cd1   proteasome (prosome; macropa             143.6091   120   133.6156   132.2946   −1.04E−01   −2.63E−01   1   Unchanged Low       Q9Y4K4   D04cd6   mitogen-activated protein kinase   132.4072   158   133.6676   141.2069   1.37E−02   2.51E−01   1   Unchanged Low       O60463   H06cd3   phosphalidic acid phosphatase              103.2417   151   133.6898   129.2479   3.73E−01   5.47E−01   1   Unchanged Low       O95639   P20cd6   cleavage and polyadenylation sp   183.1762   67.6   133.7241   128.1539   −4.54E−01   −1.44E+00   1   Unchanged Low       P50539   N19ab7   MAX interacting protein 1   175.6646   187   133.7304   165.4016   −3.93E−01   8.87E−02   1   Unchanged Low       Q9UH62   I15ef3   ALEX3 protein   118.2527   171   133.7314   140.9912   1.77E−01   5.32E−01   1   Unchanged Low       O15525   C13ab7   v-maf musculoaponeurotic fibros   105.3252   109   133.7521   116.1167   3.45E−01   5.31E−02   1   Unchanged Low       Q9H8T0   H21gh5   fused toes homolog (mouse)   106.2145   241   133.7606   160.2791   3.33E−01   1.18E+00   1   Unchanged Low       Q9Y4X5   K03cd6   ariadne homolog; ubiquitin-conju   99.46477   128   133.8771   120.4976   4.29E−01   3.66E−01   1   Unchanged Low       Q9H9E1   O01gh5   ankyrin repeat; family A (RFXAN   172.6268   78.8   134.052   128.4841   −3.65E−01   −1.13E+00   1   Unchanged Low       Q93063   F13ab3   exostoses (multiple) 2   123.2886   161   134.3468   139.4501   1.24E−01   3.82E−01   1   Unchanged Low       Q9H992   D22gh5   axotrophin   89.54768   149   134.4784   124.4411   5.87E−01   7.37E−01   1   Unchanged Low       Q43237   P02ab4   dynein; cytoplasmic; light interms   290.6769   119   134.4914   181.4903   −1.11E+00   −1.28E+00   1   Unchanged Low       Q99643   H02cd1   succinate dehydrogenase compl             143.4474   125   134.5527   134.443   −9.24E−02   −1.95E−01   1   Unchanged Low       Q24386   F11ef1   choroideremia (Rab escort protei   93.86058   129   134.5538   119.0446   5.20E−01   4.56E−01   1   Unchanged Low       Q9Y5F7   F12gh4   protocadherin gamma subfamily   101.7878   114   134.5585   116.632   4.03E−01   1.58E−01   1   Unchanged Low       P06756   D14ab6   integrin: alpha V (vitronectin recs   200.0782   219   134.6115   184.6891   −5.72E−01   1.33E−01   1   Unchanged Low       Q9H5L7   C02gh6   chromosome 1 open reading frar   173.8108   148   134.6601   152.0822   −3.68E−01   −2.34E−01   1   Unchanged Low       O15517   A14ef8   tumor necrosis factor receptor su   92.33364   207   134.6603   144.7566   5.44E−01   1.17E+00   1   Unchanged Low       Q9P0N5   K24ef2   HSPC244   107.9991   129   134.6618   123.7736   3.18E−01   2.53E−01   1   Unchanged Low       Q9NWT2   D19gh2   hypothetical protein FLJ20623   107.8864   105   134.7112   115.8334   3.20E−01   −4.05E−02   1   Unchanged Low       Q9Y2A0   O02cd7   TP53 target gene 1   127.408   88.2   134.8491   116.8334   8.19E−02   −5.30E−01   1   Unchanged Low       Q9NZ43   N16gh4   uncharacterized hematopoietic s             141.2548   137   134.9524   137.7883   −6.58E−02   −4.24E−02   1   Unchanged Low       P27986   A10af1   phosphoinosi         de-3-kinase; regul   111.3806   112   134.9586   119.3503   2.77E−01   4.28E−03   1   Unchanged Low       Q9UBP6   J13ef1   methyltransferase-like 1   107.2187   122   134.986   121.358   3.32E−01   1.85E−01   1   Unchanged Low       Q9BWK5   P24gh5   hypothetical protein MGC5242   101.1324   123   134.9881   119.8654   4.17E−01   2.88E−01   1   Unchanged Low       P54802   M24ab6   N-acelylglucosaminidase; alpha-   206.038   66.3   135.077   135.7965   −6.09E−01   −1.64E+00   1   Unchanged Low       O75963   H09cd7   G-protein coupled receptor   110.3888   184   135.3412   143.3711   2.94E−01   7.40E−01   1   Unchanged Low       Q9NXZ4   F03ef4   ELG protein   124.5205   105   135.3934   121.5448   1.21E−01   −2.50E−01   1   Unchanged Low       O60353   B11cd3   frizzled homolog 6 ( Drosophila )   85.64918   146   135.5169   122.5147   6.62E−01   7.73E−01   1   Unchanged Low       Q9NQS6   F13gh4   latexin protein   94.21822   163   135.5761   130.917   5.25E−01   7.80E−01   1   Unchanged Low       O14776   A19cd7   transcription elongation regulator   113.3803   117   135.6603   122.1137   2.59E−01   4.90E−02   1   Unchanged Low       Q9Y5A2   L13ef1   putative zinc finger protein NY-R   154.0704   186   135.6708   158.5684   −1.83E−01   2.71E−01   1   Unchanged Low       P49842   G23cd6   serine/threonine kinase 19   133.3557   171   135.7013   146.5953   2.52E−02   3.56E−01   1   Unchanged Low       Q06546   J14ab5   GA binding protein transcription              88.93312   138   135.7488   120.885   6.10E−01   6.34E−01   1   Unchanged Low       Q9Y2E7   I02ef8   KIAA0938 protein   109.8218   105   135.7763   116.739   3.06E−01   −7.00E−02   1   Unchanged Low       Q9UM11   I02ef2   Fzrl protein   80.82847   186   135.8949   134.12   7.50E−01   1.20E+00   1   Unchanged Low       Q99447   B14ab8   phosphate cytidylyltransferase 2;   174.8201   77.4   135.988   129.39   −3.62E−01   −1.18E+00   1   Unchanged Low       Q9H1R3   F22gh8   myosin light chain kinase 2; skel             93.58977   129   136.0458   119.5324   5.40E−01   4.63E−01   1   Unchanged Low       P28358   P05ab6   homeo box D10   108.9905   102   136.1419   115.6766   3.21E−01   −9.71E−02   1   Unchanged Low       O76070   P18cd1   synuclein; gamma (breast cancer   128.551   140   136.1645   134.744   8.30E−02   1.18E−01   1   Unchanged Low       Q9Y5A7   N07ef2   NEDD8 ultimate buster-1   119.0653   195   136.2606   149.951   1.95E−01   7.08E−01   1   Unchanged Low       Q9NWY7   A16gh3   hypothetical protein FLJ20530   103.7638   110   136.3026   116.6328   3.94E−01   8.20E−02   1   Unchanged Low       O43715   P02ef2   hypothetical protein HSPC132   137.4694   110   136.3043   127.9562   −1.23E−02   −3.20E−01   1   Unchanged Low       Q9BY75   K19gh8   itchy homolog E3 ubiqultin prote             118.5721   127   136.5094   127.3323   2.03E−01   9.81E−02   1   Unchanged Low       O43431   A12ef7   endothelial differentiation; lysopt   126.4659   171   136.5393   144.6131   1.11E−01   4.34E−01   1   Unchanged Low       O43567   D15cd7   ring finger protein 13   110.4449   153   136.5722   133.3964   3.06E−01   4.72E−01   1   Unchanged Low       Q9Y2S7   P13ef8   DKFZP586F1524 protein   113.1366   104   136.7041   117.8414   2.73E−01   −1.26E−01   1   Unchanged Low       O14582   O24ef2   spondyloepiphyseal dysplasia; la   135.1666   135   136.7342   135.7349   1.66E−02   1.46E−03   1   Unchanged Low       O75056   G12gh1   syndecan 3 (N-syndecan)   120.0661   162   136.797   139.562   1.88E−01   4.31E−01   1   Unchanged Low       Q9P2Y2   D18gh4   beta-1; 4 mannosyltransferase   89.6857   143   136.8208   123.2251   6.08E−01   6.75E−01   1   Unchanged Low       Q16595   M08ab3   Friedreich ataxia   139.5657   130   136.8314   135.5917   −2.85E−02   −9.82E−02   1   Unchanged Low       Q14807   B18ab7   kinesin-like 4   114.4726   94.2   136.9298   115.2048   2.58E−01   −2.81E−01   1   Unchanged Low       Q98ZL4   L10gh6   protein phosphatase 1; regulator   110.5367   123   137.0777   123.5234   3.10E−01   1.54E−01   1   Unchanged Low       P30876   I13ab8   polymerase (RNA) II (DNA direct   265.5337   200   137.1153   200.7168   −9.54E−01   −4.12E−01   1   Unchanged Low       Q9UGP6   B17cd7   coatomer protein complex; subu             94.73601   134   137.3091   122.0845   5.35E−01   5.02E−01   1   Unchanged Low       P52655   M01ef2   general transcritpion factor IIA; 1   121.4896   128   137.3707   129.1154   1.77E−01   8.08E−02   1   Unchanged Low       Q9HB07   G23gh5   chromosome 12 open reading              121.2547   118   137.4723   125.5248   1.81E−01   −4.11E−02   1   Unchanged Low       Q92940   H23ab7   MAD; mothers against decapent             414.4889   223   137.6028   258.3032   −1.59E+00   −8.95E−01   1   Unchanged Low       Q9NWN1   H19gh2   hypothetical protein FLJ20727   117.7514   120   137.6351   124.9938   2.25E−01   2.24E−02   1   Unchanged Low       O43664   A10cd6   G protein-coupled receptor 66   108.1311   102   137.6789   116.0604   3.49E−01   −7.90E−02   1   Unchanged Low       O14647   C19ab4   chromodomain helicase DNA bin   96.14804   164   137.7441   132.5407   5.19E−01   7.68E−01   1   Unchanged Low       O75333   N15cd2   T-box 10   126.0065   129   137.7737   130.9257   1.29E−01   3.38E−02   1   Unchanged Low       Q16539   J04ef5   mitogen-activated protein kinase   148.7339   219   137.8   168.4312   −1.10E−01   5.57E−01   1   Unchanged Low       Q9NQG5   A07gh5   chromosome 20 open reading fr             86.80552   143   137.803   122.4598   6.67E−01   7.18E−01   1   Unchanged Low       Q15149   E05ab8   plectin 1; intermediate filament bi   125.7248   83.9   138.0785   115.8848   1.35E−01   −5.84E−01   1   Unchanged Low       Q9NVZ7   G12gh3   hypotheitical protein FLJ10407   166.213   175   138.1444   159.6342   −2.67E−01   7.06E−02   1   Unchanged Low       Q15800   D02cd2   sterol-C4-methyl oxidase-like   171.8648   71.2   138.1497   127.0641   −3.15E−01   −1.27E+00   1   Unchanged Low       Q9H086   D16gh5   hypothetical protein FLJ12387 si   96.54943   129   138.1542   121.3672   5.17E−01   4.22E−01   1   Unchanged Low       P09001   K14cd7   mitochondrial ribosomal protein              94.17331   128   138.1601   120.1502   5.53E−01   4.44E−01   1   Unchanged Low       O00301   D24cd3   KH-type splicing regulatory prote             126.0509   88.3   138.3014   117.5428   1.34E−01   −5.14E−01   1   Unchanged Low       P55786   J19ef7   aminopeptidase puromycin sensi   273.7328   98.9   138.3924   170.346   −9.84E−01   −1.47E+00   1   Unchanged Low       Q9Y5Y9   B14cd2   sodium channel; voltage-gated;              127.3727   139   138.4331   134.9928   1.20E−01   1.28E−01   1   Unchanged Low       P19235   M01ef7   erythropoietin receptor   198.5954   77.3   138.4803   138.1099   −5.20E−01   −1.36E+00   1   Unchanged Low       O15228   A16ef3   glyceronephosphate O-acyltrans   225.1315   186   138.5137   183.349   −7.01E−01   −2.72E−01   1   Unchanged Low       Q9UK97   K05cd8   F-box only protein 9   151.0501   104   138.5593   131.097   −1.25E−01   −5.43E−01   1   Unchanged Low       P50990   D20cd6   chaperonin containing TCP1; sut   274.982   178   138.6001   197.1593   −9.88E−01   −6.28E−01   1   Unchanged Low       Q9NZM1   P19cd8   fer-1-like 3; myoferlin ( C. elegans               218.8411   202   138.6209   186.4122   −6.59E−01   −1.17E−01   1   Unchanged Low       Q92924   N20cd1   SWI/SNF related; matrix associa             131.7669   82.7   138.6764   117.704   7.37E−02   −6.73E−01   1   Unchanged Low       O75845   A18gh1   sterol-C5-desaturase (ERG3 dell   101.9285   153   138.7232   131.1198   4.45E−01   5.83E−01   1   Unchanged Low       Q9NQ88   I10gh4   chromosome 12 open reading frs   80.2401   158   138.8274   125.605   7.91E−01   9.75E−01   1   Unchanged Low       Q16515   C19ab2   amiloride-sensitive cation channe             102.1159   109   138.9915   116.6136   4.45E−01   9.06E−02   1   Unchanged Low       P49759   F16ab5   CDC-like kinase 1   86.24615   147   139.0985   124.2553   6.90E−01   7.73E−01   1   Unchanged Low       P33552   A22ab5   CDC28 protein kinase 2   109.5671   96   139.1297   114.8881   3.45E−01   −1.91E−01   1   Unchanged Low       O75808   H21cd2   small optic lobes homolog (Dros             115.654   98.9   139.1625   117.8898   2.67E−01   −2.26E−01   1   Unchanged Low       Q9NXR1   M07gh2   LIS1-interacting protein NUDE1;   96.20481   123   139.1939   119.5057   5.33E−01   3.56E−01   1   Unchanged Low       O75381   L12ab8   peroxisomal biogenesis factor 14   473.8395   113   139.2209   241.8793   −1.77E+00   −2.07E+00   1   Unchanged Low       O60930   P23cd1   ribonuclease H1   167.3611   111   139.2393   139.1464   −2.65E−01   −5.95E−01   1   Unchanged Low       O14653   P14cd4   golgl SNAP receptor complex me   115.7917   89.7   139.2541   114.9152   2.66E−01   −3.68E−01   1   Unchanged Low       Q16540   L24gh1   mitochondrial ribosomal protein              209.2433   120   139.3426   156.1365   −5.87E−01   −8.04E−01   1   Unchanged Low       O14658   P08cd2   ras-related C3 botulinum toxin SL   158.176   166   139.3634   154.6374   −1.83E−01   7.29E−02   1   Unchanged Low       Q15814   M17cd2   tubulin-specific chaperone c   103.3699   112   139.6311   118.2869   4.34E−01   1.14E−01   1   Unchanged Low       Q9Y3C9   J09ef2   CGI-127 protein   83.4762   163   139.6599   128.8568   7.42E−01   9.69E−01   1   Unchanged Low       P18827   F22cd1   syndecan 1   114.4045   92.7   139.6607   115.5895   2.88E−01   −3.03E−01   1   Unchanged Low       P04150   B21ab3   nuclear receptor subfamily 3; gro   106.6921   103   139.6889   116.6017   3.89E−01   −4.49E−02   1   Unchanged Low       Q9Y301   N05ef1   CGI-12 protein   108.0511   101   139.7035   116.3594   3.71E−01   −9.27E−02   1   Unchanged Low       O00626   F10cd1   small Inducible cytokine subfamil   113.478   106   139.8189   119.8588   3.01E−01   −9.45E−02   1   Unchanged Low           B18cd8   neural precursor cell expressed;   108.1711   133   139.9597   127.048   3.72E−01   2.98E−01   1   Unchanged Low       Q9Y311   C01ef2   mitochondrial ribosomal protein              162.8519   74.8   139.9856   125.8788   −2.18E−01   −1.12E+00   1   Unchanged Low       Q15633   K14cd2   TAR (HIV) RNA binding protein              169.3779   125   140.0138   144.9588   −2.75E−01   −4.33E−01   1   Unchanged Low       P02278   M22gh6   H2B histone family; member K   100.2794   216   140.0965   152.2309   4.82E−01   1.11E+00   1   Unchanged Low       P53672   J11cd7   crystallin; beta A2   101.7321   187   140.2804   142.8494   4.64E−01   8.75E−01   1   Unchanged Low       P09417   C05ab8   quinoid dihydropteridine reducta             126.6361   161   140.3564   142.5395   1.48E−01   3.43E−01   1   Unchanged Low       Q9HAY2   K14gh5   MAGEF1 protein   96.01675   126   140.3654   120.9341   5.48E−01   3.97E−01   1   Unchanged Low       P30273   A20ab5   Fc fragment of IgE; high affinity              88.48289   171   140.4541   133.3475   6.67E−01   9.51E−01   1   Unchanged Low       Q92949   G10ab4   forkhead box J1   250.4112   167   140.5084   185.89   −8.34E−01   −5.87E−01   1   Unchanged Low       Q9GZT9   G01gh7   egl nine homolog 1 ( C. elegans )   112.8025   99.2   140.6558   117.5626   3.18E−01   −1.85E−01   1   Unchanged Low       P35658   O23cd4   nucleoporin 214 kD (CAIN)   141.8279   137   140.7761   139.8811   −1.07E−02   −4.96E−02   1   Unchanged Low       Q9HB40   G01gh5   likely homolog of rat mouse              105.9316   99.3   140.9548   115.3964   4.12E−01   −9.32E−02   1   Unchanged Low       O14686   O16cd3   myeloid/lymphoid or mixed-linea             117.844   157   141.0674   138.5398   2.60E−01   4.11E−01   1   Unchanged Low       Q92911   O12cd1   solute carrier family 5 (sodium Io             264.1256   125   141.0904   176.594   −9.05E−01   −1.08E+00   1   Unchanged Low       Q9Y5E4   B18ef3   protocadherin beta 5   95.08061   148   141.1894   127.9379   5.70E−01   6.34E−01   1   Unchanged Low       Q13057   H17gh7   nucleotide binding protein   186.8796   125   141.2202   151.0906   −4.04E−01   −5.78E−01   1   Unchanged Low       Q14863   B23ab8   POU domain; class 6; transcripti             103.2077   103   141.3258   115.7954   4.53E−01   −4.97E−03   1   Unchanged Low       P36610   G10ef3   frequenin homolog ( Drosophila )   110.2191   136   141.4925   129.0874   3.60E−01   2.98E−01   1   Unchanged Low       O60240   O12ab8   perilipin   1121.108   52.2   141.5046   438.2653   −2.99E+00   −4.43E+00   1   Unchanged Low       Q9H9B4   P05gh5   hypothetical protein FLJ12876   87.99841   133   141.7125   120.8973   6.87E−01   5.96E−01   1   Unchanged Low       O00584   J14cd3   ribonuclease 6 precursor   124.6932   250   141.8008   172.0542   1.85E−01   1.00E+00   1   Unchanged Low       Q9H658   M04gh7   G protein-coupled receptor 107   158.2595   214   141.8139   171.1973   −1.58E−01   4.32E−01   1   Unchanged Low       P18858   K14ef6   ligase I; DNA; ATP-dependent   92.33071   128   141.8761   120.8853   6.20E−01   4.76E−01   1   Unchanged Low       Q02877   D23cd1   ribosomal protein L26   449.1728   297   141.8851   295.8854   −1.66E+00   −5.99E−01   1   Unchanged Low       P15588   J07ab4   glucosamine (N-acetyl)-6-sulfat             261.466   119   141.968   174.2861   −8.81E−01   −1.13E+00   1   Unchanged Low       P42696   H08ef4   KIAA0117 protein   110.9202   231   141.9948   161.4649   3.56E−01   1.06E+00   1   Unchanged Low       O75710   A17ef1   molybdenum cofactor synthesis              105.3087   101   142.0352   116.2449   4.32E−01   −5.47E−02   1   Unchanged Low       Q9NPI8   C01gh2   Fanconl anemia; complementalic   193.8104   214   142.0643   183.3737   −4.48E−01   1.45E−01   1   Unchanged Low       Q9HAR6   O10gh5   uterine-derived 14 kDa protein   118.9551   198   142.0669   152.8734   2.56E−01   7.32E−01   1   Unchanged Low       P15018   O18ef7   leukemia inhibitory factor (cholin             253.8099   309   142.2733   235.0602   −8.35E−01   2.84E−01   1   Unchanged Low       Q13546   A23cd4   receptor (TNFRSF)-interacting s             139.7074   131   142.2746   137.7012   2.63E−02   −9.15E−02   1   Unchanged Low       P24298   H01ab4   glutamic-pyruvate transaminase              210.426   97.1   142.3123   149.9584   −5.64E−01   −1.12E+00   1   Unchanged Low       Q14129   C22cd4   DIGeorge syndrome critical regio   112.1253   141   142.4302   131.8973   3.45E−01   3.32E−01   1   Unchanged Low       Q9BQA2   K09gh8   KIAA1882 protein   164.9357   187   142.4325   164.7437   −2.12E−01   1.80E−01   1   Unchanged Low       Q9UJX9   B12ef3   hypothetical protein; estradiol-in             121.7396   98.5   142.5053   120.9085   2.27E−01   −3.06E−01   1   Unchanged Low       Q99590   I01cd5   splicing factor; arginine/serine-ri             231.0328   199   142.5273   190.7413   −6.97E−01   −2.18E−01   1   Unchanged Low       O14798   C06ef7   tumor necrosis factor receptor su   142.6951   213   142.5294   166.073   −1.68E−03   5.78E−01   1   Unchanged Low       P32238   P01ab3   cholecystokinin A receptor   487.368   168   142.5911   265.9537   −1.77E+00   −1.54E+00   1   Unchanged Low       Q9UQ90   C17cd2   spastic paraplegia 7; paraplegin   101.2857   146   142.6321   129.9052   4.94E−01   5.26E−01   1   Unchanged Low       P82980   M03gh8   retinot binding protein 5; cellular   111.2191   93.9   142.6923   115.9454   3.60E−01   −2.44E−01   1   Unchanged Low       P49716   P15ab5   CCAAT/enhancer binding protei             169.1889   73.4   142.8277   128.4871   −2.44E−01   −1.20E+00   1   Unchanged Low       P20062   M12cd1   transcobalamin II; macrocytic an             125.6347   141   142.8402   136.6279   1.85E−01   1.71E−01   1   Unchanged Low       P21580   B06cd2   tumor necrosis factor, alpha-indu   275.8225   317   142.8664   245.0939   −9.49E−01   1.99E−01   1   Unchanged Low       Q99774   H01cd5   protein phosphatase 4; regulator   195.85   173   143.1867   170.7835   −4.52E−01   −1.76E−01   1   Unchanged Low       Q9P0T1   A17ef3   hypothetical protein HSPC192   104.4363   101   143.2517   116.1881   4.56E−01   −5.00E−02   1   Unchanged Low       P06737   B18ab8   phosphorylase; glycogen; liver (             85.14818   139   143.2732   122.6343   7.51E−01   7.12E−01   1   Unchanged Low       O15063   K10gh1   KIAA0355 gene product   149.9191   144   143.2945   145.705   −6.52E−02   −5.91E−02   1   Unchanged Low       P02743   K14ab2   amyloid P component; serum   108.0152   94.7   143.3031   115.3343   4.08E−01   −1.90E−01   1   Unchanged Low       Q9NVT0   I14gh3   hypothetical protein FLJ10534   136.4264   109   143.3056   129.6057   7.10E−02   −3.23E−01   1   Unchanged Low       Q9Y4P3   O07ef3   transducin (beta)-like 2   112.0852   104   143.4853   119.7013   3.56E−01   −1.14E−01   1   Unchanged Low       Q13886   N14ab3   basic transcription element bindi             164.4049   88.7   143.5269   132.2194   −1.96E−01   −8.90E−01   1   Unchanged Low       Q9NVP8   L19gh4   hypothetical protein FLJ10595   101.7956   106   143.5829   117.1232   4.96E−01   5.83E−02   1   Unchanged Low       P08240   G05cd2   signal recognition particle recept             158.3565   132   143.6823   144.5673   −1.40E−01   −2.66E−01   1   Unchanged Low       P49459   M19ef5   ubiquitin-conjugating enzyme E2   98.6462   170   143.74   137.6267   5.43E−01   7.89E−01   1   Unchanged Low       Q9NVAB   L16gh2   solute carrier family 38; member   112.6488   127   143.7595   127.9498   3.52E−01   1.78E−01   1   Unchanged Low       P25325   K23cd3   mercaptopyruvate sulfurtransfer             288.1435   274   143.8077   235.1972   −1.00E+00   −7.45E−02   1   Unchanged Low       Q9UHI6   K08cd7   DEAD/H (Asp-Glu-Ala-Asp-His) t   135.6699   209   143.8383   162.7208   8.43E−02   6.21E−01   1   Unchanged Low       P52298   H01cd7   nuclear cap binding protein subu   138.9223   191   143.8819   157.996   5.06E−02   4.61E−01   1   Unchanged Low       Q9NQ30   A10cd7   endothelial cell-specific molecul             104.1846   122   143.9703   123.2921   4.67E−01   2.24E−01   1   Unchanged Low       O00541   I08ef3   pescadillo homolog 1; containing   180.43   204   144.0988   176.2086   −3.24E−01   1.78E−01   1   Unchanged Low       Q9H2V9   B06gh7   hypothetical protein CDA08   173.5608   169   144.1057   162.3327   −2.68E−01   −3.56E−02   1   Unchanged Low       Q9NNX1   F12gh1   tuftelin 1   147.0323   175   144.106   155.2699   −2.90E−02   2.49E−01   1   Unchanged Low       Q13508   H14ab2   ADP-ribosyltransferase 3   109.4052   101   144.1545   118.095   3.98E−01   −1.19E−01   1   Unchanged Low       Q9NR30   B21gh6   DEADE/H (Asp-Glu-Ala-Asp/His) t   110.4836   130   144.2348   128.2929   3.85E−01   2.36E−01   1   Unchanged Low       Q14320   E15cd5   DNA segment on choromosome X   102.5057   178   144.2677   141.6929   4.93E−01   7.99E−01   1   Unchanged Low       Q04726   D03cd2   transducin-like enhancer of split:   211.8773   115   144.3217   156.9544   −5.54E−01   −8.86E−01   1   Unchanged Low       P20061   N13cd1   transcobalamin I (vitamin B12 bi             177.3445   85.5   144.4835   115.787   3.00E−01   −4.56E−01   1   Unchanged Low       Q9Y2Y1   J12ef2   polymerase (RNA) III (DNA direc   153.7426   145   144.5561   147.7222   −8.89E−02   −8.58E−02   1   Unchanged Low       P35754   G22ab5   glutaredoxin (thioltransferase)   153.823   138   144.7308   145.4287   −8.79E−02   −1.59E−01   1   Unchanged Low       Q02978   F01cd3   solute carrier family 25 (mitocho             106.877   98.2   144.7822   116.628   4.38E−01   −1.22E−01   1   Unchanged Low       O95792   N20gh2   protein associated with PRK1   130.6914   146   144.7909   140.5872   1.48E−01   1.63E−01   1   Unchanged Low       Q13232   D20ef7   non-metastaic cells 3; protein e             90.7906   156   144.8861   130.592   6.74E−01   7.82E−01   1   Unchanged Low       Q9NVH2   L01ef8   DKFZP434B168 protein   117.6587   91.2   144.9821   117.932   3.01E−01   −3.68E−01   1   Unchanged Low       Q15561   O15cd2   TEA domain family member 4   234.306   172   145.3307   183.8604   −6.89E−01   −4.46E−01   1   Unchanged Low       Q9UPN9   B01ef2   tripartite motif-containing 33   110.9269   135   145.3321   130.2668   3.90E−01   2.78E−01   1   Unchanged Low       Q14353   O06ab3   guanidinoaceate N-methyltrans             109.1385   103   145.3798   119.1987   4.14E−01   −8.24E−02   1   Unchanged Low       Q9NZM5   A18ef4   glioma tumor suppressor candid             150.098   122   145.587   139.1802   −4.40E−02   −3.01E−01   1   Unchanged Low       O43255   B11cd2   seven in absentia homolog 2 (D             114.6318   101   145.653   120.4593   3.46E−01   −1.81E−01   1   Unchanged Low       Q14331   G04ab5   FSHD region gene 1   164.0964   176   145.6576   161.7807   −1.72E−01   9.77E−02   1   Unchanged Low       P18847   N23ab5   activating transcription factor 3   127.5442   154   145.6654   142.5299   1.92E−01   2.75E−01   1   Unchanged Low       O60258   I07cd4   fibroblast growth factor 17   159.7671   223   145.6821   176.0472   −1.33E−01   4.79E−01   1   Unchanged Low       P47929   P02ab6   lectin; galactoside-binding; solub   151.1595   92.8   145.699   129.8767   −5.31E−02   −7.04E−01   1   Unchanged Low       P35227   O14cd4   zinc finger protein 144 (Mel-18)   108.2295   151   145.8554   135.0089   4.30E−01   4.80E−01   1   Unchanged Low       Q15599   O15cd5   solute carrier family 9 (sodium/h             168.9673   80.5   145.993   131.8082   −2.11E−01   −1.07E−00   1   Unchanged Low       Q9UKJ5   B20cd7   cystein-rich hydrophobic domain   184.4717   206   145.9967   178.8637   −3.37E−01   1.60E−01   1   Unchanged Low       Q9HCB9   C10gh5   chromosome 1 open reading frar   94.16759   126   146.1683   122.1779   6.34E−01   4.22E−01   1   Unchanged Low       Q9Y3A0   K07ef2   CGI-92 protein   119.1033   176   146.1698   147.7783   2.95E−01   5.80E−01   1   Unchanged Low       P49815   M17ef6   tuberous sclerosis 2   106.0159   163   146.2712   138.4231   4.64E−01   6.20E−01   1   Unchanged Low       P25116   L19ab4   coagulation factor II (thrombin) r             82.48228   143   146.2742   123.8585   8.27E−01   7.92E−01   1   Unchanged Low       O75829   O01cd7   chondromodulin I precursor   121.7658   119   146.4876   128.9495   2.67E−01   −3.81E−02   1   Unchanged Low       Q9NYI1   M16ef2   ECSIT   111.7926   110   146.6345   122.8588   3.91E−01   −2.14E−02   1   Unchanged Low       P24347   I24ef5   matrix metalloproteinase 11 (stro   97.57916   136   146.649   126.9018   5.88E−01   4.84E−01   1   Unchanged Low       O43189   K24ab8   PHD finger protein 1   112.1101   101   146.6925   120.038   3.88E−01   −1.46E−01   1   Unchanged Low       Q9P029   N22ef2   TH1-like ( Drosophila )   201.2292   159   146.6998   168.9188   −4.56E−01   −3.41E−01   1   Unchanged Low       Q9NZP9   E17ef2   immediate early response 5   105.1683   157   146.761   136.3041   4.81E−01   5.78E−01   1   Unchanged Low       Q9UIA3   I12ef2   neutral sphingomyelinase   165.6408   147   146.8134   153.0756   −1.74E−01   −1.74E−01   1   Unchanged Low       Q99734   M12ef5   Notch homolog 2 ( Drosophila )   220.4251   263   147.0111   210.2011   −5.84E−01   2.56E−01   1   Unchanged Low       O00411   C19cd1   polymerase (RNA) mitochondrial             120.5078   105   147.0481   124.1084   2.87E−01   −2.02E−01   1   Unchanged Low       P28347   P04gh1   TEA domain family member 1 (S             230.2101   174   147.0913   183.776   −6.46E−01   −4.04E−01   1   Unchanged Low       Q13619   G19gh1   cullin 4A   153.1592   218   147.2043   172.6621   −5.72E−02   5.07E−01   1   Unchanged Low       O94929   O06ef8   KIAA0843 protein   108.7821   99.4   147.2921   118.4779   4.37E−01   −1.31E−01   1   Unchanged Low       Q9P026   A02ef8   HSPC134 protein   115.4895   184   147.3205   149.0331   3.51E−01   6.74E−01   1   Unchanged Low       P28067   D08ab5   major histocompatibility complex;   128.7098   100   147.3934   125.4983   1.96E−01   −3.58E−01   1   Unchanged Low       Q14126   E11ef7   desmoglein 2   426.8387   366   147.4196   313.3393   −1.53E+00   −2.23E−01   1   Unchanged Low       Q14267   P01cd1   regulatory factor X: 4 (influences   127.7912   98.9   147.4351   124.7021   2.06E−01   −3.70E−01   1   Unchanged Low       P55197   H09ab2   myeloid/lymphold or mixed-linea             160.668   185   147.4439   164.3164   −1.24E−01   2.02E−01   1   Unchanged Low       Q9NP87   O20cd8   polymerase (DNA directed); mu   115.1765   86.7   147.4845   116.4497   3.57E−01   −4.10E−01   1   Unchanged Low       P04155   A04cd2   trefoil factor 1 (breast cancer; es             258.058   136   147.487   180.4791   −8.07E−01   −9.25E−01   1   Unchanged Low       Q9C069   N02gh7   sec13-like protein   52.65015   424   147.5255   207.9658   1.49E+00   3.01E+00   1   Unchanged Low       P12270   G14cd2   translocated promoter region (to   104.4493   136   147.7447   129.4065   5.00E−01   3.81E−01   1   Unchanged Low       Q9UIG6   I14ef2   LPAP for lysophosphatidic acid              218.3106   325   147.8779   230.2685   −5.62E−01   5.72E−01   1   Unchanged Low       O15453   P08cd5   NBR2   99.08545   108   147.9143   118.2765   5.78E−01   1.22E−01   1   Unchanged Low       Q9UNW8   F17cd8   G protein-coupled receptor   239.3255   347   148.021   244.7569   −6.93E−01   5.36E−01   1   Unchanged Low       P06746   I10ef6   polymerase (DNA directed); beta   142.5013   225   148.0351   171.8166   5.50E−02   6.58E−01   1   Unchanged Low       O15414   I08cd7   trinucleotide repeat containing 4   131.6219   199   148.0947   159.7305   1.70E−01   6.00E−01   1   Unchanged Low       O15259   L22ab7   nephronophthisis 1 (juvanile)   115.0436   110   148.3613   124.437   3.67E−01   −6.59E−02   1   Unchanged Low       Q9NRA8   P05gh4   eIF4E-transporter   106.343   178   148.4323   144.3142   4.81E−01   7.45E−01   1   Unchanged Low       Q9NP77   C10ef8   HSPC182 protein   171.17   175   148.5234   165.0639   −2.05E−01   3.60E−02   1   Unchanged Low       Q06587   P17cd1   ring finger protein 1   119.2377   127   148.657   131.6381   3.81E−01   9.12E−02   1   Unchanged Low       Q9Y5Z5   E22ef2   heme binding protein 1   181.0768   196   148.7681   175.2357   −2.84E−01   1.13E−01   1   Unchanged Low       O15327   I05cd4   inositol polyphosphate-4-phosph   183.6815   131   148.785   154.5722   −3.04E−01   −4.85E−01   1   Unchanged Low       P49646   P19cd1   regulator of mitotic spindle assen   143.9463   117   148.8487   136.7074   4.83E−02   −2.95E−01   1   Unchanged Low       Q99809   F16cd5   conserved gene amplified in oste             134.0126   91.3   148.9901   124.7728   1.53E−01   −5.53E−01   1   Unchanged Low       Q9UBM1   G02cd7   phosphatidylethanolamine N-mel   138.4849   122   149.0109   136.3565   1.06E−01   −1.86E−01   1   Unchanged Low       P16403   G04ab6   H1 histone family; member 2   427.1258   558   149.1016   377.9287   −1.52E+00   3.84E−01   1   Unchanged Low       O75503   B01ab4   ceroid-lipofuscinosis; neuronal 5   148.9991   75.4   149.1361   124.5021   1.33E−03   −9.83E−01   1   Unchanged Low       P15814   P20gh6   immunoglobulin lambada-like poly   78.91644   144   149.2005   123.9169   9.19E−01   6.64E−01   1   Unchanged Low       Q03164   N01ab7   myeloid/lymphoid or mixed-linea             157.0713   81.9   149.358   129.4559   −7.26E−02   −9.39E−01   1   Unchanged Low       Q13624   B08ef6   interleukin enhancer binding fact   136.4076   130   149.4265   138.6386   1.32E−01   −6.85E−02   1   Unchanged Low       Q14118   M02ab5   dystroglycan 1 (dystrophin-assoc   105.7987   99   149.6192   118.1383   5.00E−01   −9.59E−02   1   Unchanged Low       Q13286   E20ab3   ceroid-lipofuscinosis; neuronal 3;   240.521   302   149.6542   230.6187   −6.85E−01   3.27E−01   1   Unchanged Low       Q9Y5Q0   E15gh7   fatty acid desaturase 3   117.0825   115   149.704   127.2281   3.55E−01   −2.72E−02   1   Unchanged Low       Q9P0R1   K08ef2   forkhead box P1   99.17408   114   149.7517   120.8481   5.95E−01   1.96E−01   1   Unchanged Low       P41182   C24ab5   B-cell CLL/lymphoma 6 (zinc fing   115.9704   85.9   149.853   117.2275   3.70E−01   −4.34E−01   1   Unchanged Low       O75497   K14cd6   microspherute protein 1   145.7927   163   149.9313   153.0143   4.04E−02   1.64E−01   1   Unchanged Low       Q14185   M19ab4   dedicator of cyto-kinesis 1   95.3322   112   150.0398   118.9819   6.54E−01   2.27E−01   1   Unchanged Low       O95163   P05cd3   inhibitor of kappa light polypeptic   203.0161   120   150.0489   157.6357   −4.36E−01   −7.60E−01   1   Unchanged Low       Q14508   L05ef7   WAP four-disulfide core domain:   102.6084   201   150.0782   151.3745   5.49E−01   9.73E−01   1   Unchanged Low       P25942   M21ef7   tumor necrosis factor receptor su   110.0933   239   150.083   166.2403   4.47E−01   1.12E+00   1   Unchanged Low       Q9Y6E0   F15cd3   serine/threonine kinase 24 (STE:   206.7079   225   150.279   194.1145   −4.60E−01   1.25E−01   1   Unchanged Low       Q9UQF2   J21cd5   mitogen-activated protein kinase   229.9384   182   150.2902   187.4786   −6.13E−01   −3.36E−01   1   Unchanged Low       Q9Y285   D11ab5   phenylalanine-tRNA synthetase-             179.7613   145   150.3716   158.2291   −2.58E−01   −3.14E−01   1   Unchanged Low       Q04762   F09ab4   cell matrix adhesion regulator   134.1594   176   150.3997   153.4581   1.65E−01   3.90E−01   1   Unchanged Low       Q9Y6J9   P19ef6   TAF6-like RNA polymerase II; p3   77.59128   158   150.4181   128.6968   9.55E−01   1.03E+00   1   Unchanged Low       O43913   C06ab8   origin recognition complex; subu             147.9187   168   150.4866   155.6272   2.48E−02   1.88E−01   1   Unchanged Low       P25208   M05cd1   nuclear transcription factor Y; be             106.4662   138   150.5231   131.7807   4.99E−01   3.77E−01   1   Unchanged Low       Q9H9X4   F03gh5   hypothetical protein FLJ11618   189.58   179   150.5879   173.1977   −3.32E−01   −7.94E−02   1   Unchanged Low       O95297   P17cd4   myelin protein zero-like 1   127.461   121   150.7509   133.0095   2.42E−01   −7.72E−02   1   Unchanged Low       Q9UPG8   O06ab8   pleiomorphic adenoma gene-like   134.8747   165   150.9533   150.4388   1.62E−01   2.95E−01   1   Unchanged Low       P16333   H16ef5   NCK adaptor protein 1   237.1463   351   150.9549   246.4108   −6.52E−01   5.66E−01   1   Unchanged Low       Q14108   I22ab5   CD36 antigen (collagen type I re             155.206   139   150.9785   148.3416   −3.98E−02   −1.61E−01   1   Unchanged Low       Q9UFF9   O05cd5   CCR4-NOT transcription comple             162.9025   208   151.0687   174.1041   −1.09E−01   3.55E−01   1   Unchanged Low       O15242   O19ab8   nardilysin (N-arginine dibasic co             210.0164   198   151.1245   186.2788   −4.75E−01   −8.72E−02   1   Unchanged Low       Q13442   N15ef3   PDGFA associated protein 1   156.1376   188   151.1314   165.0545   −4.70E−02   2.67E−01   1   Unchanged Low       Q99755   A15ef6   phosphatidylinositol-4-phosphat             112.2177   146   151.3432   136.4804   4.32E−01   3.78E−01   1   Unchanged Low       Q9NZV1   E09gh2   cysteine-rich motor neuron 1   112.5932   99.1   151.3541   121.0073   4.27E−01   −1.85E−01   1   Unchanged Low       Q05195   C09ab7   MAX dimerization protein   136.8996   254   151.5662   180.6838   1.47E−01   8.89E−01   1   Unchanged Low       O95671   J14ab2   acetylserotonin O-methyltransfer             99.67178   98.5   151.7064   116.6189   6.06E−01   −1.74E−02   1   Unchanged Low       Q9Y658   A09ef2   RNA helicase   112.9715   95.3   151.8988   120.0494   4.27E−01   −2.46E−01   1   Unchanged Low       Q9BTU6   N12gh6   phosphatidylinositol 4-kinase typ   97.30862   178   151.965   142.5367   6.43E−01   8.74E−01   1   Unchanged Low       Q9UPN6   G04ef8   KIAA1116 protein   127.681   113   152.0268   130.9046   2.52E−01   −1.76E−01   1   Unchanged Low       O00170   J03ab2   aryl hydrocarbon receptor intera             555.1127   223   152.0508   310.1793   −1.87E+00   −1.31E+00   1   Unchanged Low       Q9UJW6   P01ef3   activity-regulated cytosketelon-a             221.8559   185   152.1474   186.4423   −5.44E−01   −2.60E−01   1   Unchanged Low       Q9HCT0   N02ef8   fibroblast growth factor 22   157.7471   126   152.2042   145.1536   −5.16E−02   −3.30E−01   1   Unchanged Low       Q15459   O03cd6   splicing factor 3a; subunit 1; 120             163.4432   145   152.3945   153.5048   −1.01E−01   −1.76E−01   1   Unchanged Low       O95400   G16cd6   CD2 antigen (cytoplasmic tail) b             192.2313   238   152.5257   194.1745   −3.34E−01   3.07E−01   1   Unchanged Low       P07954   M06ab3   fumarate hydratase   121.2546   142   152.5652   138.7259   3.31E−01   2.31E−01   1   Unchanged Low       Q9H6Z5   C16gh5   hypothetical protein FLJ21634   101.1467   152   152.6745   135.2933   5.94E−01   5.88E−01   1   Unchanged Low       Q9HCN8   A05gh1   stromal cell-derived factor 2-like   136.5604   128   152.9097   139.1775   1.63E−01   −9.27E−02   1   Unchanged Low       Q92890   A24cd4   ubiquitin fusion degradation 1-lik   157.2559   220   152.9538   176.6159   −4.00E−02   4.82E−01   1   Unchanged Low       O43324   N24cd4   eukaryotic translation elongation   150.6748   112   152.9613   138.6164   2.17E−02   −4.25E−01   1   Unchanged Low       Q9NVU8   H10gh2   hypothetical protein FLJ10496   145.4398   119   152.9651   139.1241   7.28E−02   −2.90E−01   1   Unchanged Low       Q9NQW6   H01ef4   anillin; actin binding protein (scr             113.8655   85.6   152.992   117.4953   4.26E−01   −4.11E−01   1   Unchanged Low       Q9NWH4   L01gh2   mitochondrial ribosomal protein              173.4347   107   153.0783   144.3461   −1.80E−01   −7.03E−01   1   Unchanged Low       Q9UBV8   M13cd8   PEF protein with a long N-termin             146.0371   144   153.0828   148.3188   4.84E−02   −4.15E−02   1   Unchanged Low       P15328   F10ab3   folate receptor 1 (adult)   152.5051   123   153.1163   142.7655   5.77E−03   −3.14E−01   1   Unchanged Low       Q9Y583   B01cd6   NS1-associated protein 1   143.6283   177   153.2797   157.8847   9.38E−02   2.99E−01   1   Unchanged Low       Q07326   M08ab8   phosphatidylinositol glycan; clas             132.6521   93   153.3084   126.3257   2.09E−01   −5.12E−01   1   Unchanged Low       O75396   M12cd5   SEC22 vesicle trafficking protein             143.9018   153   153.3626   150.1024   9.19E−02   8.88E−02   1   Unchanged Low       Q9Y2Z8   D09ef2   CGI-09 protein   117.2943   110   153.5282   126.8764   3.88E−01   −9.52E−02   1   Unchanged Low       Q9H3P7   N05gh5   golgi phosphoprotein 1   251.3681   258   153.65   220.9899   −7.10E−01   3.73E−02   1   Unchanged Low       O95678   E03cd5   cytokeratin type II   339.3692   195   153.797   229.3684   −1.14E+00   −8.00E−01   1   Unchanged Low       P17026   M04cd4   zinc finger protein 22 (KOX 15)   152.726   88.3   153.8779   131.6407   1.08E−02   −7.90E−01   1   Unchanged Low       Q9Y3N9   M05gh7   olfactory receptor; family 2; subf             127.2527   137   153.9228   139.4653   2.75E−01   1.09E−01   1   Unchanged Low       Q9BYT8   K08gh7   neurolysin (metallopeptidase M3   85.99781   193   154.0005   144.2719   8.41E−01   1.16E+00   1   Unchanged Low       Q9UHQ7   F02ef8   pp21 homolog   119.2248   136   154.0057   136.5651   3.69E−01   1.95E−01   1   Unchanged Low       O60921   A22ab7   HUS1 checkpoint homolog (S. p             148.5716   204   154.126   169.0172   5.29E−02   4.60E−01   1   Unchanged Low       O00400   D05ab2   acetyl-Coenzyme A transporter   196.9505   124   154.2012   158.3654   −3.53E−01   −6.68E−01   1   Unchanged Low       Q9Y690   H01gh6   mortality factor 4   253.2426   259   154.2307   222.1522   −7.15E−01   3.23E−02   1   Unchanged Low       Q9NZL9   L24ef7   methionine adenosyltransferase   128.4144   99.7   154.2681   127.4733   2.65E−01   −3.65E−01   1   Unchanged Low       O60563   A05ab4   cyclin T1   179.5706   171   154.2911   168.3854   −2.19E−01   −6.81E−02   1   Unchanged Low       P20591   M03ab7   myxovirus (influenza virus) resist   459.0611   873   154.338   495.4752   −1.57E+00   9.27E−01   1   Unchanged Low       Q9BQC6   P14gh5   mitochondrial ribosomal protein              188.6422   74.3   154.357   139.1028   −2.89E−01   −1.34E+00   1   Unchanged Low       P28838   J02ef1   leucine aminopeptidase 3   409.1007   383   154.3828   315.6553   −1.41E+00   −9.33E−02   1   Unchanged Low       Q9NZE5   P08ef1   hypothetical protein LOC51319   135.1502   171   154.3904   153.3881   1.92E−01   3.36E−01   1   Unchanged Low       Q9NX47   K10gh2   hypothetical protein FLJ20445   299.3918   338   154.4327   263.9291   −9.55E−01   1.75E−01   1   Unchanged Low       O60612   K11cd2   supervillin   113.628   270   154.4497   179.421   4.43E−01   1.25E+00   1   Unchanged Low       O00559   F22cd4   estrogen receptor binding site as   181.5726   147   154.679   160.9495   −2.31E−01   −3.09E−01   1   Unchanged Low       Q9NUU9   E17gh3   hypothetical protein F23149_1   140.3785   224   154.7106   172.9723   1.40E−01   6.73E−01   1   Unchanged Low       P22059   C10ab8   oxysterol binding protein   133.2924   93.6   154.8714   127.2507   2.16E−01   −5.10E−01   1   Unchanged Low       O00408   I05ef6   phosphodiesterase 2A; cGMP-sti   860.2983   169   154.9688   394.9107   −2.47E+00   −2.34E+00   1   Unchanged Low       O94935   P22ef7   SAC1 suppressor of actin mutati             146.0417   128   154.9914   142.9113   8.58E−02   −1.94E−01   1   Unchanged Low       P41134   H15ef5   inhibitor of DNA binding 1; domi             434.1844   292   155.0439   293.8674   −1.49E+00   −5.70E−01   1   Unchanged Low       P24407   M08ab7   mel transforming oncogene (deri             224.1153   189   155.1684   189.5598   −5.30E−01   −2.43E−01   1   Unchanged Low       O00232   N05ab8   proteasome (prosome; macropa             122.517   139   155.2465   139.0276   3.42E−01   1.85E−01   1   Unchanged Low       Q01432   G04ab2   adenosine monophosphate dea             111.1766   117   155.341   127.7664   4.83E−01   7.10E−02   1   Unchanged Low       Q13525   G15cd4   interleukin 1 receptor-like 2   136.0802   130   155.4674   140.5051   1.92E−01   −6.63E−02   1   Unchanged Low       Q16611   N04ab3   BCL2-antagonist/killer 1   280.4131   194   155.5414   210.0516   −8.50E−01   −5.30E−01   1   Unchanged Low       Q9NPA3   C11gh5   hyphothetical protein STRAIT114             112.5378   85.5   155.5531   117.8671   4.67E−01   −3.96E−01   1   Unchanged Low       Q9GZM8   D14gh7   LIS1-interacting protein NUDEL;   137.8235   131   155.5611   141.4354   1.75E−01   −7.41E−02   1   Unchanged Low       P42702   P06ab6   leukemia inhibitory factor recept             92.44914   112   155.6189   120.0363   7.51E−01   2.77E−01   1   Unchanged Low       Q05940   P07ef5   solute carrier family 10 (vesicular   374.4901   153   155.637   227.6447   −1.27E+00   −1.29E+00   1   Unchanged Low       Q9Y3Q5   H18cd6   putative DNA/chromatin binding              75.96908   150   155.6726   127.0621   1.04E+00   9.77E−01   1   Unchanged Low       Q15756   H08ab7   potassium inwardly-rectifying ch             149.0689   80.9   155.7504   128.583   6.33E−02   −8.81E−01   1   Unchanged Low       O75386   M17cd3   tubby like protein 3   128.6914   82.7   155.7811   122.3782   2.76E−01   −6.39E−01   1   Unchanged Low       P50750   D03ef5   cyclin-dependent kinase 9 (CDC:   270.8229   215   155.8317   213.7777   −7.97E−01   −3.35E−01   1   Unchanged Low       Q9NWY6   A18gh3   hypothetical protein FLJ20531   91.85185   130   156.1332   125.9903   7.65E−01   5.01E−01   1   Unchanged Low       P50391   K05cd1   pancreatic polypeptide receptor   136.5278   112   156.1953   134.9143   1.94E−01   −2.85E−01   1   Unchanged Low       Q9NX07   L20gh6   tRNA selenocysteine associated   258.434   287   156.2449   233.9363   −7.26E−01   1.52E−01   1   Unchanged Low       O75354   A15ab4   ectonucleoside triphosphate dip             386.4989   258   156.4638   267.133   −1.30E+00   −5.81E−01   1   Unchanged Low       Q9H832   L12gh5   hypothetical protein FLJ13855   173.4437   307   156.9292   212.3427   −1.44E−01   8.22E−01   1   Unchanged Low       Q9UBW8   F18ef1   COP9 constitutive photomorpho             102.8052   111   157.0119   123.4686   6.11E−01   1.05E−01   1   Unchanged Low       P14136   E23ab5   glial fibriliary acidic protein   108.166   86.6   157.2761   117.3353   5.40E−01   −3.21E−01   1   Unchanged Low       Q9NYF3   F08ef1   chromosome 5 open reading frar   121.4116   94.3   157.5806   124.4392   3.76E−01   −3.64E−01   1   Unchanged Low       Q15056   A09gh2   Williams-Beuren syndrome chror   202.4969   124   157.6763   161.3602   −3.61E−01   −7.09E−01   1   Unchanged Low       O15534   I16ab8   period homolog 1 ( Drosophila )   237.2007   143   157.7195   179.3665   −5.89E−01   −7.28E−01   1   Unchanged Low       Q9Y399   O21ef2   mitochondrial ribosomal protein              229.9134   139   157.7339   175.5893   −5.44E−01   −7.25E−01   1   Unchanged Low       O14972   A04cd6   Down syndrome critical region g             230.0837   267   157.7386   218.3678   −5.45E−01   2.16E−01   1   Unchanged Low       Q14113   M15ab2   AE binding protein 1   124.9796   95.3   157.955   126.0667   3.38E−01   −3.92E−01   1   Unchanged Low       O95755   O18cd5   RA836; member RAS oncogene   132.9919   97   158.0474   129.3518   2.49E−01   −4.55E−01   1   Unchanged Low       Q9NPC3   I09gh4   enhancer of invasion 10   104.2128   121   158.1023   127.8011   6.01E−01   2.17E−01   1   Unchanged Low       Q9Y6E9   N24cd7   sirtuin silent mating type informal   111.8557   153   158.2227   140.9006   5.00E−01   4.48E−01   1   Unchanged Low       Q9Y5B8   D17cd8   NME7   92.69165   116   158.2444   122.4719   7.72E−01   3.30E−01   1   Unchanged Low       P49642   I21ab6   primase; polypeptide 1 (49 kD)   135.2376   70.2   158.2887   121.2327   2.27E−01   −9.47E−01   1   Unchanged Low       O60660   J04ab2   ash2 (absent; small; or homeotic   274.3502   177   158.3372   203.1619   −7.93E−01   −6.34E−01   1   Unchanged Low       Q9H251   O08gh7   cadherin related 23   113.1038   184   158.4524   151.9031   4.86E−01   7.03E−01   1   Unchanged Low       Q9Y6C2   A22cd7   elastin microfibril interface locate   107.9751   92.2   158.6648   119.6097   5.55E−01   −2.28E−01   1   Unchanged Low       O95825   D13cd5   crystallin; zeta (quinone reducta             144.0183   133   158.6719   145.1487   1.40E−01   −1.17E−01   1   Unchanged Low       Q9UHG3   J02ef2   prenylcysteine lyase   250.3969   207   158.8419   205.2993   −6.57E−01   −2.77E−01   1   Unchanged Low       O00629   J18ab6   karyopherin alpha 4 (importin alp   518.8184   295   158.8458   324.141   −1.71E+00   −8.16E−01   1   Unchanged Low       Q15397   B14gh1   KIAA0020 gene product   109.8533   134   158.9595   134.3527   5.33E−01   2.89E−01   1   Unchanged Low       Q14999   H01gh1   KIAA0076 gene product   71.35119   173   159.0037   134.6153   1.16E+00   1.28E+00   1   Unchanged Low       Q12772   M18cd2   sterol regulatory element binding   158.6108   94.6   159.1986   137.4667   5.34E−03   −7.46E−01   1   Unchanged Low       O75150   F09gh1   ring finger protein 40   129.2351   169   159.2038   152.3442   3.01E−01   3.84E−01   1   Unchanged Low       O43423   L07gh6   acidic (leucine-rich) nuclear pho             140.3006   143   159.4372   147.5392   1.84E−01   2.63E−02   1   Unchanged Low       O43311   D12cd8   muscleblind-like ( Drosophila )   165.2243   99.4   159.4681   141.3508   −5.12E−01   −7.34E−01   1   Unchanged Low       Q9NYX4   B07ef4   calcyon; D1 dopamine receptor-             207.2791   147   159.5302   171.42   −3.78E−01   −4.91E−01   1   Unchanged Low       Q9HD71   G04gh4   hypothetical nuclear factor SBB             123.7874   140   159.5491   141.2517   3.66E−01   1.82E−01   1   Unchanged Low       Q9NZH2   N03cd8   replication initiation region prote             225.0949   179   159.6113   187.9443   −4.96E−01   −3.30E−01   1   Unchanged Low       Q9NVH1   B05gh3   hypothetical protein FLJ10737   137.4673   217   159.6304   171.2625   2.16E−01   6.57E−01   1   Unchanged Low       Q9NVG3   B11gh3   hypothetical protein FLJ10751   96.28296   105   159.6829   120.1783   7.30E−01   1.19E−01   1   Unchanged Low       P52179   A21cd4   myomesin 1 (skelemin) (185 kD)   157.0608   94   159.8272   136.9676   2.52E−02   −7.40E−01   1   Unchanged Low       O94815   B09cd3   frizzled homolog 1 ( Drosophila )   93.97877   101   159.9198   118.2939   7.67E−01   1.04E−01   1   Unchanged Low       Q9UBY9   G01ef4   heat shock 27 kD protein family;              98.97552   102   160.1725   120.3216   6.94E−01   4.08E−02   1   Unchanged Low       Q9NVX7   G18gh3   hypothetical protein FLJ10450   111.5198   121   160.2507   130.905   5.23E−01   1.17E−01   1   Unchanged Low       O95704   A02cd6   FE65-like protein 2   99.35088   115   160.3239   124.7475   6.90E−01   2.06E−01   1   Unchanged Low       P19801   A23ab2   amiloride binding protein 1 (amin   164.6296   68.3   160.3477   131.0836   −3.80E−02   −1.27E+00   1   Unchanged Low       O43709   L18ef3   Williams Beuren syndrome chror   127.8538   134   160.4415   140.7855   3.28E−01   6.84E−02   1   Unchanged Low       Q12839   N24ef1   H326   109.677   116   160.6141   128.8096   5.50E−01   8.26E−02   1   Unchanged Low       O43503   D10ab8   RAD51 homolog C ( S. cerevisiae     96.34779   97.6   160.6551   118.1934   7.38E−01   1.83E−02   1   Unchanged Low       Q07898   J10cd4   CD163 antigen   87.73563   177   160.8614   141.7231   8.75E−01   1.01E+00   1   Unchanged Low       O96015   F22cd5   dynein; axonemal; light polypepti   94.54055   251   160.9963   168.8465   7.68E−01   1.41E+00   1   Unchanged Low       Q92524   L11ab8   proteasome (prosome; macropal             396.6515   220   161.0391   259.1291   −1.30E+00   −8.52E−01   1   Unchanged Low       Q92692   B06ab8   pollovirus receptor-related 2 (her   302.7185   317   161.2569   260.2905   −9.09E−01   6.60E−02   1   Unchanged Low       Q9Y6Y8   I16cd7   Sec23-interacting protein p125   104.2429   131   161.2684   132.2965   6.30E−01   3.34E−01   1   Unchanged Low       Q9NZ78   J16gh3   uncharcterized bone marrow pn   107.2001   127   161.3587   131.7449   5.90E−01   2.41E−01   1   Unchanged Low       Q15120   G15cd1   pyruvate dehydrogenases kinase;   96.64061   107   161.6468   121.6758   7.42E−01   1.43E−01   1   Unchanged Low       P35241   F22ab8   radixin   276.6012   213   161.7003   216.9693   −7.74E−01   −3.80E−01   1   Unchanged Low       Q9Y326   D23ef2   brain specific protein   359.3582   160   161.7123   227.0406   −1.15E+00   −1.17E+00   1   Unchanged Low       Q92600   J03cd5   RCD1 required for cell differentia   115.6633   145   161.7142   140.923   4.84E−01   3.30E−01   1   Unchanged Low       O00487   N14cd5   26S proteasome-associated pad             329.3518   275   161.8834   255.4035   −1.02E+00   −2.60E−01   1   Unchanged Low       Q9Y689   P21cd7   ADP-ribosylation factor-like 5   137.7737   159   161.8965   152.9706   2.33E−01   2.09E−01   1   Unchanged Low       Q9ULB8   P05cd8   CMP-NeuAC: (beta)-N-acetylgala   91.01128   121   161.9148   124.5785   8.31E−01   4.09E−01   1   Unchanged Low       O60897   L09cd7   RAB; member of RAS oncogene   89.32474   112   162.0127   120.9939   8.59E−01   3.22E−01   1   Unchanged Low       P51809   J05cd2   synaptobrevin-like 1   228.3546   141   162.1052   177.2043   −4.94E−01   −6.94E−01   1   Unchanged Low       O75581   A03ab7   low density lipoprotein receptor-r   122.4708   125   162.1159   136.4087   4.05E−01   2.53E−02   1   Unchanged Low       O43795   F12ef4   myosin class I; myh-1c   259.4543   282   162.137   234.504   −6.78E−01   1.20E−01   1   Unchanged Low       Q14188   H17ef5   transcription factor Dp-2 (E2F dir   107.308   204   162.1489   157.7494   5.96E−01   9.25E−01   1   Unchanged Low       P06280   B07ab3   galactosidase; alpha   178.0238   304   162.2871   214.6169   −1.34E−01   7.70E−01   1   Unchanged Low       Q14541   O17ab7   hepatocyte nuclear factor 4; gam   549.8997   283   162.4659   331.895   −1.78E+00   −9.57E−01   1   Unchanged Low       P57723   E17gh8   poly(rC) binding protein 4   186.2845   231   162.5267   193.1283   −1.97E−01   3.08E−01   1   Unchanged Low       Q9NWU3   A24gh3   DEAD/H (Asp-Glu-Ala-Asp/His) t   154.71   104   162.6529   140.5056   7.22E−02   −5.71E−01   1   Unchanged Low       Q9NPC5   J16ef8   nudix (nucleoside diphosphate              107.1863   98.4   162.6929   122.7442   6.02E−01   −1.24E−01   1   Unchanged Low       Q9Y3C5   B19ef3   ring finger protein 11   160.0631   184   162.7518   162.3366   2.40E−02   3.68E−02   1   Unchanged Low       Q9NWX3   B01gh2   chromosome 20 open reading fr             98.58482   95.6   162.7744   118.9844   7.23E−01   −4.44E−02   1   Unchanged Low       P52742   I22cd3   zinc finger portein 135 (clone pH   81.4141   121   162.8382   121.6363   1.00E+00   −4.44E−02   1   Unchanged Low       Q9Y313   D17ef2   PTD013 protein   90.25232   116   1634053   123.3545   8.56E−01   3.67E−01   1   Unchanged Low       Q9P2W9   B11ef4   syntaxin 18   128.6426   188   163.4277   160.0555   3.45E−01   5.48E−01   1   Unchanged Low       P14778   F09ab6   interleukin 1 receptor; type I   264.5401   539   163.4432   322.4754   −6.95E−01   1.03E+00   1   Unchanged Low       Q15464   I12ef5   SHB (Src homology 2 domain co             284.291   301   163.5379   249.6096   −7.98E−01   8.24E−02   1   Unchanged Low       O15444   H07cd2   small inducible cytokine subfamily   244.6426   97.1   163.6053   168.4558   −5.80E−01   −1.33E+00   1   Unchanged Low       P49796   P14ef4   regulator of G-protein signalling:              220.2769   99.3   163.6222   161.0774   −4.29E−01   −1.15E+00   1   Unchanged Low       Q9NUS7   B04gh3   hypothetical protein FLJ11164   81.76063   114   163.6422   119.7258   1.00E+00   4.77E−01   1   Unchanged Low       P48651   L11ef3   phosphatidylserine synthase 1   211.8695   139   163.6792   171.5708   −3.72E−01   −6.06E−01   1   Unchanged Low       Q07706   F15cd4   tetracycline transporter-like prote             143.0791   144   163.7206   150.2019   1.94E−01   7.31E−01   1   Unchanged Low       O75143   B11gh1   KIAA0652 gene product   106.5331   155   163.7687   141.6405   6.20E−01   5.37E−01   1   Unchanged Low       O75039   L19gh1   KIAA0451 gene product   174.142   135   163.8572   157.7714   −8.78E−02   −3.64E−01   1   Unchanged Low       P02261   M10gh6   H2A histone family; member N   93.48591   273   163.8621   176.9259   8.10E−01   1.55E+00   1   Unchanged Low       Q9H9A0   L20gh5   hypothetical protein FLJ12895   86.42599   130   164.3655   126.7707   9.27E−01   5.84E−01   1   Unchanged Low       Q9NV35   J21gh3   hypothetical protein FLJ10958   99.15342   154   164.4852   139.1489   7.30E−01   6.33E−01   1   Unchanged Low       Q9P1G8   C05gh4   WW domain-containing adapter              119.4436   182   164.5311   155.3256   4.62E−01   6.08E−01   1   Unchanged Low       P26368   D11cd7   U2 small nuclear ribonucleoprote             217.0564   107   164.8861   163.126   −3.97E−01   −1.01E+00   1   Unchanged Low       Q9BSZ7   E11gh8   DEAD/H (Asp-Glu-Ala-Asp/His) t   130.7858   111   164.9084   135.6059   3.34E−01   −2.35E−01   1   Unchanged Low       Q9Y391   G23ef2   androgen-regulated short-chain              222.3497   128   164.9823   171.7067   −4.31E−01   −7.99E−01   1   Unchanged Low       Q9NYR5   E05ef3   HSPC126 protein   99.37243   110   165.2098   124.8579   7.33E−01   1.46E−01   1   Unchanged Low       P05165   N12ab7   propionyl Coenzyme A carboxyla             100.892   120   165.6902   128.9755   7.16E−01   2.54E−01   1   Unchanged Low       Q9NPF4   O21gh3   O-slaloglycoprotein endopeptida             103.8223   112   165.9716   127.3658   6.77E−01   1.13E−01   1   Unchanged Low       P16106   D01cd3   H3 histone family; member K   99.19006   130   166.1216   131.6683   7.44E−01   3.87E−01   1   Unchanged Low       P35249   O03ef5   replication factor C (activator 1)              105.2406   98.7   166.2092   123.3812   6.59E−01   −9.27E−02   1   Unchanged Low       P28702   P18gh1   retinoid X receptor; beta   74.914   142   166.2214   127.7227   1.15E+00   9.23E−01   1   Unchanged Low       P49674   K14ab4   casein kinase 1: epsilon   99.33956   145   166.3564   136.8564   7.44E−01   5.44E−01   1   Unchanged Low       Q9NXW2   I03gh2   DnaJ (Hsp40) homolog; subfamily   247.7907   235   166.4412   216.5041   −5.74E−01   −7.47E−02   1   Unchanged Low       O14672   I01ab2   a disintegin and metalloprateina   378.0042   226   166.5417   258.8185   −1.18E+00   −7.43E−01   1   Unchanged Low       Q9Y5B9   I20cd7   chromatin-specific transcription              163.0543   188   166.6045   172.4726   3.11E−02   2.04E−01   1   Unchanged Low       Q9H9J2   H22gh5   mitochondrial ribosomal protein              206.428   256   166.8142   209.7386   −3.07E−01   3.10E−01   1   Unchanged Low       P23759   G06ab8   paired box gene 7   92.41833   200   166.8514   153.0178   8.52E−01   1.11E+00   1   Unchanged Low       Q16643   L05ab4   drebrin 1   265.008   152   166.9734   194.7352   −6.66E−01   −8.00E−01   1   Unchanged Low       P48454   I21cd1   protein phosphatase 3 (formerly              105.9496   169   167.0428   147.2674   6.57E−01   6.72E−01   1   Unchanged Low       Q9Y508   F21ef4   zinc finger protein 313   331.595   395   167.2366   297.9139   −9.88E−01   2.52E−01   1   Unchanged Low       P19474   G09cd2   Siogren syndrome antigen A1 (5             301.1776   183   167.414   217.1349   −8.47E−01   −7.20E−01   1   Unchanged Low       P46109   N13ab5   v-crk sarcoma virus CT10 oncog             151.2065   141   167.7716   153.202   1.50E−01   −1.05E−01   1   Unchanged Low       P54855   B19cd4   UDP glycosyltransferase 2 family   137.8939   127   167.8346   144.2152   2.83E−01   −1.20E−01   1   Unchanged Low       Q14242   H14cd1   selectin P ligand   112.9679   130   167.9184   136.8261   5.72E−01   1.98E−01   1   Unchanged Low       Q9BSS1   P17gh8   hypothetical protein FLJ14525   86.75908   113   167.974   122.482   9.53E−01   3.78E−01   1   Unchanged Low       Q9Y3B2   L23ef1   homolog of yeast exosomal core   152.0751   140   167.9915   153.2264   1.44E−01   −1.23E−01   1   Unchanged Low       P31391   N03cd1   somatostatin receptor 4   147.3942   92.5   168.0254   135.9754   1.89E−01   −6.72E−01   1   Unchanged Low       O60623   O03ab4   diptheria toxin resistance protein   210.9658   170   168.0762   183.0009   −3.28E−01   −3.12E−01   1   Unchanged Low       Q99959   L24ab8   plakophilin 2   362.9423   211   168.1655   247.4823   −1.11E+00   −7.80E−01   1   Unchanged Low           B21gh7   leukocyte immunoglobullin-like re             139.2571   234   168.1829   180.4876   2.72E−01   7.49E−01   1   Unchanged Low       Q01658   P18ab5   down-regulator of transcription 1             205.2249   122   168.2606   165.0596   −2.87E−01   −7.54E−01   1   Unchanged Low       Q9HCS4   P10gh7   HMG-box transcription factor TCI   76.48423   156   168.2926   133.5936   1.14E+00   1.03E+00   1   Unchanged Low       Q9P035   N20ef2   butyrate-induced transcript 1   102.716   142   168.3034   137.5999   7.12E−01   4.65E−01   1   Unchanged Low       Q9C0K7   P24gh3   amyotrophic lateral sclerosis 2 (             102.352   108   168.4355   126.1345   7.19E−01   7.24E−02   1   Unchanged Low       Q9NYF4   I13ef3   chromosome 5 open reading frar   89.72908   137   168.4424   131.7509   9.09E−01   6.11E−01   1   Unchanged Low       P30042   M19cd4   chromosome 21 open reading fra             98.84241   97.5   168.5171   121.6076   7.70E−01   −2.03E−02   1   Unchanged Low       O75325   K16cd6   glioma amplified on chromosome   116.3239   83.3   168.5172   122.705   5.35E−01   −4.82E−01   1   Unchanged Low       Q9Y670   N01ef2   transient receptor potential calio             96.41826   90.8   168.5297   118.5764   8.06E−01   −8.69E−02   1   Unchanged Low       Q9UPRB   I14ef8   KIAA1084 protein   101.3235   111   168.5336   126.797   7.34E−01   1.26E−01   1   Unchanged Low       Q9Y2X7   I21ef4   G protein-coupled receptor kinas   160.7403   167   168.7352   165.5706   7.00E−02   5.72E−02   1   Unchanged Low       P47872   D24cd1   secretin receptor   174.6672   209   168.738   184.1802   −4.98E−02   2.60E−01   1   Unchanged Low       O43353   C17cd4   receptor-interacting serine-thre             272.5279   388   168.7722   276.5684   −6.91E−01   5.11E−01   1   Unchanged Low       P32321   P14ab5   dCMP deaminase   218.5685   60.1   168.8404   149.1554   −3.72E−01   −1.86E+00   1   Unchanged Low       O43612   J16ab4   hypocrelin (orexin) neuropeptide   66.45691   194   168.9064   143.2577   1.35E+00   1.55E+00   1   Unchanged Low       Q92874   M15ab4   deoxyribonuclease I-like 2   218.1787   146   168.9596   177.8201   −3.69E−01   −5.76E−01   1   Unchanged Low       Q9UI90   I15ef8   PRO0038 protein   89.17218   389   168.9849   215.61   9.22E−01   2.12E+00   1   Unchanged Low       P30519   N05ab6   heme oxygenase (decycling) 2   586.3897   387   169.1269   380.9032   −1.79E+00   −5.99E−01   1   Unchanged Low       Q9NVE7   D03gh3   hypothetical protein FLJ10782   141.6695   148   169.2644   152.9283   2.57E−01   6.16E−02   1   Unchanged Low       Q9P010   A14ef8   HSPC154 protein   227.9143   246   169.4393   214.317   −4.28E−01   1.08E−01   1   Unchanged Low       Q9UH59   M04cd8   bromodomain-containing 7   147.6635   103   169.5045   139.9456   1.99E−01   −5.24E−01   1   Unchanged Low       Q9UM82   E01cd6   spermatogenesis associated 2   230.7114   221   169.6678   207.1298   −4.43E−01   −6.20E−02   1   Unchanged Low       Q9P2Y4   N14ef1   zinc finger protein 219   105.6753   175   169.7666   150.1216   6.84E−01   7.27E−01   1   Unchanged Low       Q9GZS3   H19gh7   recombination protein REC14   124.7245   162   169.9984   152.3724   4.47E−01   3.81E−01   1   Unchanged Low       P07686   J17ab3   hexosaminidase B (beta polypep   217.0423   135   170.0092   174.0094   −3.52E−01   −6.85E−01   1   Unchanged Low       Q9NZV6   L06ef2   selenoprotein X; 1   241.3633   202   170.0232   204.3052   −5.05E−01   −2.60E−01   1   Unchanged Low       O14678   E17cd1   ATP-binding cassette; sub-family   77.65216   127   170.0525   124.9148   1.13E+00   7.10E−01   1   Unchanged Low       P29972   O04ab2   aquaporin 1 (channel-forming in             309.1218   134   170.2078   204.2885   −8.61E−01   −1.21E+00   1   Unchanged Low       O95373   D03cd6   RAN binding protein 7   247.4368   113   170.45   177.0459   −5.38E−01   −1.13E+00   1   Unchanged Low       Q15436   O12cd6   Sec23 homolog A ( S. cerevisiae )   90.05071   100   170.9386   120.3545   9.25E−01   1.52E−01   1   Unchanged Low       Q9BQ67   K23gh6   glutamate rich WD repeat protein   140.3198   112   170.966   141.0924   2.85E−01   −3.25E−01   1   Unchanged Low       P35321   D21gh6   small proline-rich protein 1A   62.28271   237   171.0104   156.8515   1.46E+00   1.93E+00   1   Unchanged Low       Q9UPQB   I10ef8   KIAA1094 protein   76.76245   123   171.0467   123.4833   1.16E+00   6.76E−01   1   Unchanged Low       O43292   A19cd4   GPAA1P anchor attachment prot   95.36294   92.4   171.0704   119.6038   8.43E−01   −4.59E−02   1   Unchanged Low       Q9UBM3   G02cd1   proteasome (prosome; macropai             287.6026   204   171.1554   221.0285   −7.49E−01   −4.93E−01   1   Unchanged Low       P19338   M20ab7   nucleolin   148.8642   87.6   171.2094   135.8947   2.02E−01   −7.65E−01   1   Unchanged Low       Q9NPE6   E17gh1   sperm associated antigen 4   111.172   135   171.4356   139.3341   6.25E−01   2.84E−01   1   Unchanged Low       O00442   J12cd3   RTC domain containing 1   274.6701   279   171.531   241.6967   −6.79E−01   2.20E−02   1   Unchanged Low       P28356   D09ef1   homeo box D9   84.5638   106   171.5949   120.5873   1.02E+00   3.21E−01   1   Unchanged Low       P49447   G06ef1   cytochrome b-561   174.7152   167   171.6447   171.1671   −2.56E−02   −6.39E−02   1   Unchanged Low       Q9UQA4   P18cd4   nuclear factor (erythroid-derived   227.4253   470   171.8945   289.7702   −4.04E−01   1.05E+00   1   Unchanged Low       O15254   D09ab2   acyl-Coenzyme A oxidase 3; pris   192.2301   192   172.0218   185.2853   −1.60E−01   −4.71E−03   1   Unchanged Low       Q9NWW6   B11gh2   hypothetical protein FLJ20559   198.7861   220   172.0261   197.0098   −2.09E−01   1.48E−01   1   Unchanged Low       O75391   M08cd5   sperm associated antigen 7   154.1159   140   172.0658   155.2376   1.59E−01   −1.43E−01   1   Unchanged Low       Q92959   H19cd2   solute carrier family 21 (prostag             86.25485   102   172.112   120.1434   9.97E−01   2.43E−01   1   Unchanged Low       O00499   G06ab2   bridging integrator 1   162.8584   111   172.4453   148.8447   8.25E−02   −5.50E−01   1   Unchanged Low       Q14197   J05ab6   Immature colon carcinoma trans             90.92583   102   172.5526   121.725   9.24E−01   1.62E−01   1   Unchanged Low       Q9NXS9   K15gh2   hypothetical protein FLJ20071   121.4575   103   172.5552   132.3749   5.07E−01   −2.36E−01   1   Unchanged Low       O75954   N18cd6   tetraspan transmembrane 4 sup             83.06795   119   172.5557   124.8565   1.05E+00   5.16E−01   1   Unchanged Low       Q9UJY9   E17cd8   lifeguard   156.5909   75.6   172.6495   134.9529   1.41E−01   −1.05E+00   1   Unchanged Low       P82912   F10gh5   mitochondrial ribosomal protein              105.0578   196   172.7091   158.0886   7.17E−01   9.03E−01   1   Unchanged Low       Q12918   J02ab6   killer cell lectin-like receptor sub             205.6225   290   172.8141   222.8453   −2.51E−01   4.97E−01   1   Unchanged Low       Q14789   E01ab6   golgi autoantigen; golgin subfam   96.09162   194   173.0059   154.2154   8.48E−01   1.01E+00   1   Unchanged Low       Q04206   I23ef6   v-rel reticuloendotheliosis viral              328.9295   242   173.0443   248.1568   −9.27E−01   −4.40E−01   1   Unchanged Low       P19838   M15ef5   nuclear factor of kappa light poly   229.2262   277   173.0997   226.323   −4.05E−01   2.71E−01   1   Unchanged Low       Q92748   A24cd2   thyroid hormone responsive (SP             101.3906   88.2   173.314   120.9562   7.73E−01   −2.02E−01   1   Unchanged Low       O95095   P13ab2   amyloid beta precursor protein (             199.951   201   173.3314   191.35   −2.06E−01   5.88E−03   1   Unchanged Low       P52209   K18ab8   phosphogluconate dehydrogena             211.8178   147   173.42   177.5327   −2.89E−01   −5.23E−01   1   Unchanged Low       P42566   H10ef5   epidermal growth factor receptor   194.9437   158   173.4643   175.3861   −1.68E−01   −3.05E−01   1   Unchanged Low       Q13772   D05gh6   nuclear receptor coactivator 4   273.5167   367   173.5038   271.4641   −6.57E−01   4.26E−01   1   Unchanged Low       P43897   D09gh6   Ts translation elongation factor;              325.7575   226   173.8489   241.8156   −9.06E−01   −5.28E−01   1   Unchanged Low       P09329   D08ef7   phosphoribosyl pyrophosphate              103.7882   86.2   174.5738   121.5057   7.50E−01   −2.69E−01   1   Unchanged Low       O75616   F24cd4   death effector domain-containing   172.0163   176   174.7689   174.3849   2.29E−02   3.61E−02   1   Unchanged Low       Q9UHI9   B18ef1   flavohemoprotein b5 + b5R   169.2028   197   174.7919   180.2862   4.69E−02   2.18E−01   1   Unchanged Low       Q9H824   J07gh6   F-box only protein 22   89.2751   161   175.62   141.9533   9.76E−01   8.50E−01   1   Unchanged Low       Q9UQ43   G07ab3   BAI1-associated protein 2   184.8198   165   175.6399   175.1475   −7.35E−02   −1.64E−01   1   Unchanged Low       Q43173   N08ef1   sialyltransferase 8C (alpha2; 3Ga   220.9909   256   175.9869   217.6266   −3.29E−01   2.12E−01   1   Unchanged Low       Q9BZZ2   G13gh7   sialoadhesin   147.52   189   175.9952   170.7942   2.55E−01   3.56E−01   1   Unchanged Low       Q92611   I16gh1   KIAA0212 gene product   96.3144   94.3   176.0348   122.2106   8.70E−01   −3.08E−02   1   Unchanged Low       Q969V6   K14gh7   megakaryoblastic leukemia (tran             135.6533   161   176.0531   157.6423   3.76E−01   2.49E−01   1   Unchanged Low       P08107   K14ab7   heat shock 70 kD protein 1B   153.5141   106   176.1145   145.1219   1.98E−01   −5.38E−01   1   Unchanged Low       Q9BQ24   E21gh6   hypothetical protein MGC2550   153.9741   255   176.3889   195.2182   1.96E−01   7.29E−01   1   Unchanged Low       Q9H7X1   N07gh5   hypothetical protein FLJ14153   155.291   236   176.5938   189.2819   1.85E−01   6.03E−01   1   Unchanged Low       Q99616   D09cd2   small inducible cytokine subfamil             130.1641   100   176.5958   135.6192   4.40E−01   −3.79E−01   1   Unchanged Low       Q92896   L04cd7   golgi apparatus protein 1   97.73429   90.3   176.622   121.5361   8.54E−01   −1.15E−01   1   Unchanged Low       Q14582   J16ef6   Mad4 homolog   210.3185   244   176.6383   210.1876   −2.52E−01   2.12E−01   1   Unchanged Low       Q13505   K21ab7   metaxin 1   199.1231   168   176.6745   181.2437   −1.73E−01   −2.46E−01   1   Unchanged Low       Q13722   O24cd8   chromosome 3p21.1 gene seque   85.85963   144   176.7101   135.6336   1.04E+00   7.49E−01   1   Unchanged Low       P01308   I10ab6   insulin   367.022   113   176.7437   218.8465   −1.05E+00   −1.70E+00   1   Unchanged Low       O00405   D19ab8   protein phosphatase 1; regulator   233.0866   306   176.8763   238.6383   −3.98E−01   3.92E−01   1   Unchanged Low       P41215   E03ab5   fatty-acid-Coenzyme A ligase; lo             267.9822   199   177.1301   214.8046   −5.97E−01   −4.27E−01   1   Unchanged Low       P31314   F04ef6   homeo box 11 (T-cell lymphoma   107.4127   170   177.4236   151.5175   7.24E−01   6.60E−01   1   Unchanged Low       O95427   G21cd8   phosphatidylinositol glycan; clas             84.22817   116   177.4629   125.8189   1.08E+00   4.59E−01   1   Unchanged Low       Q12981   C24ef6   BCL2/adenovirus E1B 19 kD inte             82.38214   99.8   177.5246   119.9152   1.11E+00   2.77E−01   1   Unchanged Low       Q9Y5V1   L10ef1   HSPC042 protein   212.074   184   177.7635   191.3703   −2.55E−01   −2.03E−01   1   Unchanged Low       Q9H4B4   O22ab4   cytokine-inducible kinase   161.982   194   177.788   177.8629   1.34E−01   2.59E−01   1   Unchanged Low       Q9H6D1   P15gh5   chromosome 20 open reading fra             95.43432   108   177.8526   126.9312   8.98E−01   1.72E−01   1   Unchanged Low       O60504   J18cd5   vinexin beta (SH3-containing ad             109.3831   99.8   177.8876   129.0088   7.02E−01   −1.33E−01   1   Unchanged Low       Q9UNK0   I02cd5   syntaxin 8   218.2149   171   177.9777   189.0342   −2.94E−01   −3.53E−01   1   Unchanged Low       O95657   B24cd4   proline-serine-threonine phosph             369.9485   158   178.0072   235.2956   −1.06E+00   −1.23E+00   1   Unchanged Low       P20645   C05ab7   mannose-6-phosphate receptor (   355.8249   234   178.1318   256.0667   −9.98E−01   −6.03E−01   1   Unchanged Low       O14569   B03ab2   putative tumor suppressor   122.4884   79.2   178.136   126.62   5.40E−01   −6.28E−01   1   Unchanged Low       O15293   D18cd3   MAP-kinase activating death don   157.092   114   178.1677   149.8523   1.82E−01   −4.59E−01   1   Unchanged Low       P00390   E14ef7   glutathione reductase   282.1492   196   178.1741   218.8246   −6.63E−01   −5.24E−01   1   Unchanged Low       Q9HBV3   K24gh5   PP3111 protein   229.2714   361   178.4093   256.1517   −3.62E−01   6.54E−01   1   Unchanged Low       Q14558   H17ab8   phosphoribosyl pyrophosphate              301.219   227   178.4567   235.5213   −7.55E−01   −4.09E−01   1   Unchanged Low       O14710   F01ef5   cell cycle progression 2 protein   261.2178   189   178.7923   209.7103   −5.47E−01   −4.66E−01   1   Unchanged Low       Q9UJ70   J10ef3   N-acetylglucosamine kinase   151.2986   276   178.7992   201.9381   2.41E−01   8.66E−01   1   Unchanged Low       Q13397   M18cd6   zinc finger protein 238   215.883   285   178.9318   226.5893   −2.71E−01   4.00E−01   1   Unchanged Low       Q9NRG4   B21gh4   HSKM-B protein   143.1326   279   178.999   200.3335   3.23E−01   9.62E−01   1   Unchanged Low       P51449   B01cd2   RAR-related orphan receptor C   236.6977   97.2   179.0372   170.992   −4.03E−01   −1.28E+00   1   Unchanged Low       Q9H768   O21gh7   synaptotagmin-like 2   83.78255   121   179.0813   128.0355   1.10E+00   5.33E−01   1   Unchanged Low       Q14332   F22ef5   frizzled homolog 2 ( Drosophila )   86.25011   129   179.1323   131.3078   1.05E+00   5.76E−01   1   Unchanged Low       Q13207   N13cd2   T-box 2   118.9378   108   179.1858   135.2524   5.91E−01   −1.44E−01   1   Unchanged Low       Q9H6B8   B19gh5   hypothetical protein similar to mc   134.338   129   179.5015   147.5119   4.18E−01   −6.19E−02   1   Unchanged Low       O00462   J09ab7   mannosidase; beta A; lysosomal   83.23817   107   179.6953   123.2365   1.11E+00   3.59E−01   1   Unchanged Low       Q9Y3D8   H14ef2   adrenal gland protein AD-004   178.4931   163   179.7989   173.7578   1.05E−02   −1.31E−01   1   Unchanged Low       P17900   F19ab3   GM2 ganglioside activator protein   124.7747   232   179.914   178.9058   5.28E−01   8.95E−01   1   Unchanged Low       Q9P0M4   O10cd8   Interleukin 17C   260.8753   223   180.0241   221.2511   −5.35E−01   −2.27E−01   1   Unchanged Low           F13gh8   G protein-coupled receptor 54   87.92591   133   180.0735   133.5723   1.03E+00   5.94E−01   1   Unchanged Low       Q9NZ92   J02gh3   SWI/SNF related; matrix associa   267.7307   247   180.206   231.4963   −5.71E−01   −1.19E−01   1   Unchanged Low       Q9NX94   L18gh6   hypothetical protein FLJ20154   133.6318   165   180.3424   159.7713   4.32E−01   3.07E−01   1   Unchanged Low       P04049   G12ef5   v-raf-1 murine leukemia viral onc   225.086   183   180.3925   196.2063   −3.19E−01   −2.98E−01   1   Unchanged Low       Q13181   B06cd1   ATP-binding cassette; sub-family   167.9383   127   180.4651   158.5133   1.04E−01   −4.02E−01   1   Unchanged Low       P22102   M05ab6   phosphoribosylglycinamide form   295.0489   180   180.5026   218.4202   −7.09E−01   −7.15E−01   1   Unchanged Low       Q9NQZ8   A09gh5   endothelial zinc finger protein inc   96.79284   138   180.7283   138.4428   9.01E−01   5.10E−01   1   Unchanged Low       Q9UN30   D04cd2   sex comb on midleg-like 1 (Droso   97.47885   86   181.0121   121.4921   8.93E−01   −1.81E−01   1   Unchanged Low       P26651   J04ef6   zinc finger protein 36; C3H type;   286.0733   162   181.0638   209.8211   −6.60E−01   −8.17E−01   1   Unchanged Low       P18887   O06ef6   X-ray repair complementing defa   85.61601   102   181.0778   122.9254   1.08E+00   2.54E−01   1   Unchanged Low       Q9Y2S0   P14ef1   RNA polymerase I 16 kDa subun   182.9338   149   181.2184   170.8985   −1.36E−02   −3.00E−01   1   Unchanged Low       P49023   I05ef7   paxillin   313.7788   334   181.2995   276.3491   −7.91E−01   9.00E−02   1   Unchanged Low       P49321   O03ab7   nuclear autoantigenic sperm prot   119.903   78.2   181.3524   126.4866   5.97E−01   −6.17E−01   1   Unchanged Low       Q13428   M14cd1   Treacher Collins-Franceschetti s   164.3621   123   181.4282   156.2838   1.43E−01   −4.18E−01   1   Unchanged Low       Q9HCS6   G07gh4   vacuolar protein sorting 11 (yeas   177.2833   302   181.4601   220.0848   3.36E−02   7.66E−01   1   Unchanged Low       P20813   I02gh6   cytochrome P450; subfamily IIB (   122.3562   162   181.476   155.3947   5.69E−01   4.08E−01   1   Unchanged Low       O00459   C05cd1   phosphoinositide-3-kinase; regul   145.3741   160   181.534   162.3275   3.20E−01   1.39E−01   1   Unchanged Low       P50151   H24ab4   guanine nucleotide binding prote   186.5329   193   182.0963   187.0796   −3.47E−02   4.62E−02   1   Unchanged Low       Q16850   D12ab3   cytochrome P450; 51 (lanosterol   353.9667   116   182.1309   217.3331   −9.59E−01   −1.61E+00   1   Unchanged Low       Q9ULW3   J09cd8   TATA-binding protein-binding pro   97.23454   207   182.1565   162.0616   9.06E−01   1.09E+00   1   Unchanged Low       Q16378   O20cd7   proline rich 4 (lacrimal)   81.91   152   182.3589   138.8678   1.15E+00   8.95E−01   1   Unchanged Low       P41240   J14ab4   c-src tyrosine kinase   175.1285   153   182.4257   170.0806   5.89E−02   −1.98E−01   1   Unchanged Low       Q16649   G05cd1   nuclear factor; interleukin 3 regul   353.6698   169   182.4266   235.1072   −9.55E−01   −1.06E+00   1   Unchanged Low       Q9Y3M2   J03ef8   chromosome 22 open reading fr             74.27488   194   182.6022   150.2264   1.30E+00   1.38E+00   1   Unchanged Low       Q9UK58   M14gh4   cyclin L anla-6a   191.3619   313   182.6351   229.0134   −6.73E−02   7.10E−01   1   Unchanged Low       P47874   M23cd1   olfactory marker protein   250.3691   172   182.73   201.6274   −4.54E−01   −5.43E−01   1   Unchanged Low       O95620   O03cd7   protein similar to  E. coli  yhdg and   227.8932   207   183.1055   205.8925   −3.16E−01   −1.14E−01   1   Unchanged Low       Q9UHV2   J11cd8   CDK4-binding protein p34SEI1   144.2806   163   183.5211   163.6559   3.47E−01   1.77E−01   1   Unchanged Low       P02810   F07gh6   proline-rich protein HaeIII subfan   410.3478   392   183.6977   328.6668   −1.16E+00   −6.62E−02   1   Unchanged Low       O94903   K04cd7   proline synthetase co-transcriber   242.2062   146   183.9744   190.7733   −3.97E−01   −7.29E−01   1   Unchanged Low       Q9P0W6   I03ef4   lipopolysaccharide specific respc   149.1418   177   184.0725   169.9232   3.04E−01   2.43E−01   1   Unchanged Low       Q9H8X4   O15gh5   stromal membrane-associated pr   358.1542   342   184.0879   294.6026   −9.60E−01   −6.84E−02   1   Unchanged Low       P02786   D24ef5   transferrin receptor (p90; CD71)   320.8365   257   184.2545   254.0696   −8.00E−01   −3.19E−01   1   Unchanged Low           E15ef1   immunoglobulin heavy constant              386.489   176   184.3533   249.0303   −1.07E+00   −1.13E+00   1   Unchanged Low       Q99717   J01ab7   MAD; mothers against decapents   227.5817   153   184.3978   188.4757   −3.04E−01   −5.69E−01   1   Unchanged Low       Q15036   B23gh1   sorting nexin 17.   303.8909   411   184.4831   299.6453   −7.20E−01   4.34E−01   1   Unchanged Low       P31751   A08ab2   v-akt murine thymoma viral onco             253.7531   253   184.8245   230.4512   −4.57E−01   −5.57E−03   1   Unchanged Low       P11177   G21ab8   pyruvate dehydrogenase (lipoam   229.1486   150   185.0719   188.1769   −3.08E−01   −6.08E−01   1   Unchanged Low       Q9UEQ6   F22ab2   arrestin; beta 2   190.7331   128   185.1221   167.9086   −4.31E−02   −5.77E−01   1   Unchanged Low       Q16531   J11ab5   damage-specific DNA binding pr             205.1934   229   185.1363   206.5357   −1.48E−01   1.60E−01   1   Unchanged Low       P28698   G24cd3   zinc finger protein 42 (myeloid-sp   76.12612   105   185.3347   122.3029   1.28E+00   4.70E−01   1   Unchanged Low       P41968   N12ef4   melanocortin 3 receptor   225.3987   287   185.5363   232.6783   −2.81E−01   3.49E−01   1   Unchanged Low       P54920   E03cd4   N-ethylmalelmide-sensitive factor   306.753   267   185.697   252.9933   −7.24E−01   −2.03E−01   1   Unchanged Low       Q99487   C19ab8   platelet-activating factor acetylhy   228.4138   241   185.7091   218.5222   −2.99E−01   8.00E−02   1   Unchanged Low       Q9H0C8   N15gh7   integrin-linked kinase-associated   120.8459   109   185.7532   138.517   6.20E−01   −1.49E−01   1   Unchanged Low       P17252   F17ab8   protein kinase C; alpha   108.3851   74   185.8466   122.7553   7.78E−01   −5.50E−01   1   Unchanged Low       P06493   B01ef5   cell division cycle 2; G1 to S and   108.1696   76.2   185.8754   123.4207   7.81E−01   −5.05E−01   1   Unchanged Low       O00139   C14ab7   kinesin heavy chain member 2   140.4141   205   185.9437   177.1988   4.05E−01   5.48E−01   1   Unchanged Low       P54259   N05ef6   dentatorubral-pallidoluysian atro             165.5295   152   186.0962   167.773   1.69E−01   −1.26E−01   1   Unchanged Low       Q99757   G10cd8   thioredoxin 2   309.0415   163   186.106   219.4587   −7.32E−01   −9.21E−01   1   Unchanged Low       Q9NW68   B12gh2   hypothetical protien FLJ10276   107.4044   242   186.1575   178.6551   7.93E−01   1.17E+00   1   Unchanged Low       P16106   O16gh6   H3 histone family; member J   137.9914   135   186.2589   152.9203   4.33E−01   −3.69E−02   1   Unchanged Low       P40692   M06ef6   mutL homolog 1; colon cancer; n   98.77988   108   186.2872   131.0441   9.15E−01   1.30E−01   1   Unchanged Low       Q99798   E01ab2   aconilase 2; mitochondrial   615.211   291   186.5524   364.1757   −1.72E+00   −1.08E+00   1   Unchanged Low       P53618   A11ef3   coatomer protein complex; subur   238.4951   102   186.6268   175.716   −3.54E−01   −1.23E+00   1   Unchanged Low       Q9UJ69   N24gh2   Toll-interacting protein   211.4055   259   186.6408   219.0188   −1.80E−01   2.93E−01   1   Unchanged Low       Q9NRM2   P22ef8   zinc finger protein 277   232.9567   227   186.8854   215.6334   −3.18E−01   −3.70E−02   1   Unchanged Low       Q92879   B06cd6   CUG triplet repeat; RNA binding   217.3752   198   187.122   200.6744   −2.16E−01   −1.38E−01   1   Unchanged Low       O75399   H22gh1   deformed epidermal autoregulator   189.8387   266   187.2872   214.4669   −1.95E−02   4.88E−01   1   Unchanged Low       Q9BZE4   I17cd8   G protein-binding protein CRFG   151.2547   214   187.3094   184.3092   3.08E−01   5.03E−01   1   Unchanged Low       Q9NXB2   G08gh2   hypothetical protein FLJ20343   259.0672   285   187.4246   243.8822   −4.67E−01   1.38E−01   1   Unchanged Low       O95424   M06ef4   MYLE protein   103.2077   184   187.5574   158.2861   8.62E−01   8.35E−01   1   Unchanged Low       P54577   D14cd3   tyrosyl-tRNA synthetase   145.5748   108   187.5756   146.9084   3.66E−01   −4.36E−01   1   Unchanged Low       O43692   N03ef7   protease inhibitor 15   102.5299   163   187.7565   150.9471   8.73E−01   6.65E−01   1   Unchanged Low       O60507   J03cd3   tyrosylprotein sulfotransferase 1   190.271   136   188.0843   171.4862   −1.67E−02   −4.83E−01   1   Unchanged Low       Q9BYS9   B15gh5   MMS19-like (MET18 homolog; S.   99.29429   117   188.1006   134.7877   9.22E−01   2.36E−01   1   Unchanged Low       P32780   G11ab6   general transcription factor IIH; p   258.9396   180   188.3175   209.0492   −4.59E−01   −5.25E−01   1   Unchanged Low       Q14004   D07ef5   cell division cycle 2-like 5 (cholin   92.56943   158   188.3656   146.1954   1.02E+00   7.68E−01   1   Unchanged Low       Q15910   L08ab5   enhancer of zeste homolog 2 (Dr   213.1801   306   188.8314   235.9636   −1.75E−01   5.21E−01   1   Unchanged Low       P47974   H22ab4   zinc finger protein 36; C3H type-I   187.7102   163   188.8801   179.8162   8.96E−03   −2.05E−01   1   Unchanged Low       Q13177   E20ab8   p21 (CDKN1A)-activated kinase.   367.7706   232   188.9048   262.9597   −9.61E−01   −6.63E−01   1   Unchanged Low           P16gh8   baculoviral IAP repeat-containing   251.3679   126   189.0052   188.6409   −4.11E−01   −1.00E+00   1   Unchanged Low       P98172   J01ef7   ephrin-B1   122.8828   109   189.5198   140.4039   6.25E−01   −1.75E−01   1   Unchanged Low       Q9BQB1   N04gh6   hypothetical protein FLJ10342   113.908   172   189.7648   158.4309   7.36E−01   5.91E−01   1   Unchanged Low       O75472   H11cd5   DnaJ (Hsp40) homolog; subfamil   227.1041   204   189.9354   206.8756   −2.58E−01   −1.58E−01   1   Unchanged Low       O75608   K06cd6   lysophospholipase I   357.6112   374   190.1833   307.2824   −9.11E−01   6.48E−02   1   Unchanged Low       O00193   E14ef3   small acidic protein   223.9793   284   190.2397   232.7223   −2.36E−01   3.42E−01   1   Unchanged Low       Q14452   B08ab5   glucocorticoid receptor DNA binc             158.8451   147   190.439   164.6255   2.80E−01   −9.75E−02   1   Unchanged Low       P55268   P18ef6   laminin; beta 2 (laminin S)   125.0717   152   190.5787   155.8763   6.08E−01   2.81E−01   1   Unchanged Low       Q9P006   A20ef8   mitochondrial ribosomal protein              114.6952   151   190.6578   152.156   7.33E−01   3.98E−01   1   Unchanged Low       Q9Y385   P07ef1   CGI-111 protein   158.6983   176   190.6804   175.2567   2.65E−01   1.52E−01   1   Unchanged Low       Q9NQ34   A10gh4   chromosome 11 open reading fra             144.3438   161   190.6944   165.3815   4.02E−01   1.59E−01   1   Unchanged Low       Q9NWY4   O14gh2   hypothetical protein FLJ20534   70.02507   110   191.0561   123.5579   1.45E+00   6.46E−01   1   Unchanged Low       Q9UBS8   P17ab2   ring finger protein 14   227.9827   247   191.1542   221.9109   −2.54E−01   1.13E−01   1   Unchanged Low       Q9UBS4   J06ef2   DnaJ (Hsp40) homolog; subfamil             181.8446   175   191.2168   182.7428   7.25E−02   −5.40E−02   1   Unchanged Low       Q12797   J22ab2   aspartate beta-hydroxylase   101.2251   86.5   191.3988   126.3618   9.19E−01   −2.27E−01   1   Unchanged Low       Q9H4I9   P10gh8   hypothetical gene supported by              167.5049   219   191.4831   192.7801   1.93E−01   3.89E−01   1   Unchanged Low       O14907   E24ef8   Tax interaction protein 1   351.7729   403   191.7684   315.6313   −8.75E−01   1.97E−01   1   Unchanged Low       Q14673   B09gh1   Bcl-2-associated transcription fa             97.16912   117   191.9499   135.533   9.82E−01   2.74E−01   1   Unchanged Low       Q9NWB7   P01gh2   estrogen-related receptor beta III   567.7076   84.6   192.0982   281.455   −1.56E+00   −2.75E+00   1   Unchanged Low       Q9BVH4   G21gh6   hypothetical protein MGC3196   164.8572   169   192.4133   175.4765   2.23E−01   3.72E−02   1   Unchanged Low       P22897   I17ab7   mannose receptor; C type 1   77.30638   100   192.4612   123.4215   1.32E+00   3.78E−01   1   Unchanged Low       P19012   L04ab6   keratin 15   146.5632   130   192.6097   156.5003   3.94E−01   −1.69E−01   1   Unchanged Low       Q14738   C16cd1   protein phosphatase 2; regulator   224.4642   183   192.7984   200.124   −2.19E−01   −2.94E−01   1   Unchanged Low       O95152   F04cd4   vesicle trafficking protein   197.6319   196   192.9314   195.3686   −3.47E−02   −1.53E−02   1   Unchanged Low       P78426   A09cd3   NK6 transcription factor homolog   198.5291   353   193.0203   248.2544   −4.06E−02   8.31E−01   1   Unchanged Low       Q14790   P14ab3   caspase 8; apoptosis-related cys   124.8603   284   193.1013   200.6718   6.29E−01   1.19E+00   1   Unchanged Low       P07711   N13ab4   cathepsin L   137.16   121   193.1454   150.5861   4.94E−01   −1.75E−01   1   Unchanged Low       P32942   B02ab6   Intercellular adhesion molecule 3   140.3673   140   193.1656   157.6897   4.61E−01   −8.57E−03   1   Unchanged Low           L18ab2   ATPase; Na+/K+ transporting; al             188.9371   131   194.2503   171.3764   4.00E−02   −5.29E−01   1   Unchanged Low       Q9NWS0   F13gh2   hypothetical protein FLJ20643   81.29108   107   194.4652   127.6547   1.26E+00   3.99E−01   1   Unchanged Low       Q9NWZ5   O06gh2   uridine kinase-like 1   176.188   358   194.4782   242.9739   1.42E−01   1.02E+00   1   Unchanged Low       O75792   D15cd6   ribonuclease HI; large subunit   100.3515   99.6   194.705   131.5441   9.56E−01   −1.12E−02   1   Unchanged Low       P05141   I04ab2   solute carrier family 25 (mitocho             454.9832   311   194.7577   320.3918   −1.22E+00   −5.47E−01   1   Unchanged Low       Q9NX38   K22gh2   hypothetical protein FLJ20457   140.7383   161   195.2668   165.7012   4.72E−01   1.95E−01   1   Unchanged Low       Q9Y682   A18cd8   sec22 homolog   193.7656   271   195.3918   220.1941   1.21E−02   4.86E−01   1   Unchanged Low       P78381   C02cd4   solute carrier family 35 (UDP-gal             276.1892   207   195.6585   226.4009   −4.97E−01   −4.14E−01   1   Unchanged Low       Q9UMP5   B23ef3   replication initiation region prote             270.4297   179   195.6957   214.9641   −4.67E−01   −5.97E−01   1   Unchanged Low       Q9P0Q0   C15ef3   hypothetical protein HSPC228   129.6054   241   195.7376   188.838   5.95E−01   8.96E−01   1   Unchanged Low       Q9UBQ3   M12cd7   polyamine-modulated factor 1   189.4397   172   195.7465   185.7473   4.72E−02   −1.39E−01   1   Unchanged Low       P27540   D22ab2   aryl hydrocarbon receptor nuclea             239.4814   258   195.776   231.071   −2.91E−01   1.07E−01   1   Unchanged Low       Q9Y2W1   F03cd5   thyroid hormone receptor-associ             160.2008   248   195.7775   201.3236   2.89E−01   6.30E−01   1   Unchanged Low       P82267   E15ab4   adaptor-related protein complex   198.6022   231   195.7793   208.571   −2.07E−02   2.20E−01   1   Unchanged Low       P00918   C16ab3   carbonic anhydrase II   283.4506   172   195.9099   216.9569   −5.33E−01   −7.25E−01   1   Unchanged Low       Q9Y663   E07cd6   heparan sulfate (glucosamine) 3-             259.052   99.8   196.1045   184.9847   −4.02E−01   −1.38E+00   1   Unchanged Low       Q9NX40   K18gh2   ovarian carcinoma immunoreacti             119.6155   247   196.1836   187.7106   7.14E−01   1.05E+00   1   Unchanged Low       P50222   L09ab7   mesenchyme homeo box 2 (grow             165.3048   223   196.5502   195.0839   2.50E−01   4.34E−01   1   Unchanged Low       Q13610   C16cd7   nuclear phosphoprotein similar t             160.8948   331   196.7055   229.4375   2.90E−01   1.04E+00   1   Unchanged Low       P49591   B12cd2   seryl-tRNA synthetase   152.5268   69.6   196.7944   139.6467   3.68E−01   −1.13E+00   1   Unchanged Low       P04554   C19gh5   protamine 3   314.8934   296   196.9835   269.3189   −6.77E−01   −8.89E−02   1   Unchanged Low       P02538   N12ef6   keratin 6A   227.8925   277   197.1759   233.9139   −2.09E−01   2.80E−01   1   Unchanged Low       Q13637   G23cd7   RAB32; member RAS oncogene   392.0158   269   197.2609   286.1382   −9.91E−01   −5.43E−01   1   Unchanged Low       P39086   J02ab3   glutamate receptor; ionotropic; k             184.3318   210   197.334   197.2285   9.83E−02   1.88E−01   1   Unchanged Low       Q9H8F9   H20gh5   hypothetical protein 24432   287.08   202   197.402   228.8927   −5.40E−01   −5.06E−01   1   Unchanged Low       Q99460   L13ab8   proteasome (prosome; macropa             298.3527   228   197.4025   241.22   −5.96E−01   −3.89E−01   1   Unchanged Low       Q9UKP6   D20gh1   G protein-coupled receptor 14   213.3717   142   197.5131   184.3366   −1.11E−01   −5.86E−01   1   Unchanged Low       Q16589   A04ef5   cyclin G2   99.61434   214   197.5658   170.3526   9.88E−01   1.10E+00   1   Unchanged Low       O95316   M03cd5   ribosomal protein S6 kinase; 90 k   144.8234   145   197.5662   162.324   4.48E−01   −2.40E−03   1   Unchanged Low       O14545   A09cd7   FLN29 gene product   238.4292   288   197.8936   241.5146   −2.69E−01   2.74E−01   1   Unchanged Low       Q9Y249   P03cd6   homologous to yeast nitrogon pe             191.1146   224   198.1049   204.4863   5.18E−02   2.31E−01   1   Unchanged Low       Q92794   K12cd4   zinc finger protein 220   134.123   179   198.312   170.3523   5.64E−01   4.13E−01   1   Unchanged Low       P36894   A12ab3   bone morphogenetic protein rece             149.2953   236   198.4963   194.5315   4.11E−01   6.59E−01   1   Unchanged Low       P79525   L21ab7   MHC class I polypeptide-related   120.8289   125   198.5782   148.0291   7.17E−01   4.53E−02   1   Unchanged Low       O14947   K04ab6   laminin; beta 3 (nicein (125 kD);              360.8887   284   199.2636   281.2972   −8.57E−01   −3.47E−01   1   Unchanged Low       Q12899   K16cd3   tripartite motif-containing 26   188.6935   250   199.2998   212.5994   7.89E−02   4.05E−01   1   Unchanged Low           M24gh8   zinc finger protein 289; ID1 regul             91.37228   137   199.4969   142.4645   1.13E+00   5.79E−01   1   Unchanged Low       Q9UIJ5   A18ef2   zinc finger; DHHC domain contai             436.5048   452   199.696   362.7132   −1.13E+00   5.01E−02   1   Unchanged Low       P46821   J11ab7   microtubule-associated protein 1   121.2356   136   199.8286   152.4972   7.21E−01   1.70E−01   1   Unchanged Low       O60906   P04cd1   sphingomyelin phosphodiesteras   282.5771   281   199.835   254.5351   −5.00E−01   −7.08E−03   1   Unchanged Low       P04040   O18ab5   catalase   160.7098   239   199.9283   199.8034   3.15E−01   5.71E−01   1   Unchanged Low       O60709   B16cd5   dynamin 1-like   85.33527   220   199.9492   168.4792   1.23E+00   1.37E+00   1   Unchanged Low       Q14714   A02cd4   sarcospan (Kras oncogene-asso             378.724   148   200.1413   242.1486   −9.20E−01   −1.36E+00   1   Unchanged Low       P39687   F01cd4   acidic (leucine-rich) nuclear pho             226.8272   108   200.186   178.3873   −1.80E−01   −1.07E+00   1   Unchanged Low       O75341   K16cd4   BRCA1 associated protein   151.895   209   200.2666   187.1088   3.99E−01   4.62E−01   1   Unchanged Low       Q9NUN1   D16gh3   hypothetical protein FLJ11259   152.5767   196   200.5435   182.989   3.94E−01   3.60E−01   1   Unchanged Low       Q9UHR5   L22ef7   transcriptional regulator protein   225.1172   345   200.7483   256.9591   −1.65E−01   6.16E−01   1   Unchanged Low       Q9UMX3   D15gh8   BCL2-related ovarian killer   185.2616   176   200.9857   187.4707   1.18E−01   −7.26E−02   1   Unchanged Low       Q02297   J05ef6   neuregulin 1   89.51288   234   201.3025   175.0464   1.17E+00   1.39E+00   1   Unchanged Low       Q9BQ83   A21gh6   hypothetical protein MGC5178   302.7768   398   201.3498   300.7124   −5.89E−01   3.95E−01   1   Unchanged Low       O43491   C22ab4   erythrocyte membrane protein b             265.5557   144   201.5208   203.6633   −3.98E−01   −8.84E−01   1   Unchanged Low       Q92922   N16cd1   SWI/SNF related; matrix associa             251.3134   195   201.571   216.0309   −3.18E−01   −3.64E−01   1   Unchanged Low       Q16099   J11ef3   glutamate receptor; ionotropic; k             200.0311   288   201.66   229.9201   1.17E−02   5.26E−01   1   Unchanged Low       O95328   B06gh4   hypothetical protein 626   253.2751   240   201.6989   231.7737   −3.29E−01   −7.56E−02   1   Unchanged Low       Q06265   C15cd1   polymyositis/scleroderma autoan   167.3169   182   202.2097   183.9827   2.73E−01   1.25E−01   1   Unchanged Low       Q01780   K12gh6   polymyositis/scleroderma autoan   196.9508   270   202.2308   223.1866   3.82E−02   4.57E−01   1   Unchanged Low       Q9NPF9   G07ef3   HeLa cyclin-dependent kinase 2   251.6953   170   202.5242   207.9337   −3.14E−01   −5.70E−01   1   Unchanged Low       Q9P1U0   B03ef4   zinc ribbon domain containing; 1   110.7474   151   202.7351   154.8483   8.72E−01   4.48E−01   1   Unchanged Low       Q13480   C02ab5   GRB2-associated binding protein   171.5634   150   203.065   174.7367   2.43E−01   −1.98E−01   1   Unchanged Low       O95205   O05gh1   C3H-type zinc finger protein; sim             138.7838   267   203.3797   202.2261   5.72E−01   9.62E−01   1   Unchanged Low       O76091   I11cd1   nitrilase 1   194.24   179   203.4317   192.2638   6.67E−02   −1.17E−01   1   Unchanged Low       Q9Y364   F21ef2   DKFZP434J154 protein   208.15   322   203.5516   244.4561   −3.22E−02   6.28E−01   1   Unchanged Low       P51116   I14cd5   fragile X mental retardation; auto   215.9784   213   203.6388   210.8166   −8.49E−02   −2.12E−02   1   Unchanged Low       P49915   H19cd4   guanine monphosphate syntheta             175.5001   115   203.6534   164.6237   2.15E−01   −6.13E−01   1   Unchanged Low       Q9UHR3   O04cd8   nasopharyngeal carcinoma susc             120.0173   196   203.8212   173.3257   7.64E−01   7.09E−01   1   Unchanged Low       Q15007   O10cd5   Wllms&#39; tumour 1-associating prot             237.1077   258   204.228   233.0967   −2.15E−01   1.22E−01   1   Unchanged Low       P24941   B03ef5   cyclin-dependent kinase 2   98.60804   214   204.3554   172.2468   1.05E+00   1.12E+00   1   Unchanged Low       P53634   L01ef7   cathepsin C   97.3314   77.9   204.771   126.6548   1.07E+00   −3.22E−01   1   Unchanged Low       Q13123   K03ef7   IK cytokine; down-regulator of H             108.6134   153   204.9565   155.5636   9.16E−01   4.95E−01   1   Unchanged Low       Q9NUT6   P21gh3   hypothetical protein FLJ11151   285.3106   565   205.0219   351.7208   −4.77E−01   9.85E−01   1   Unchanged Low       Q9Y279   B23cd7   Ig superfamily protein   356.8489   226   205.0366   262.6019   −7.99E−01   −6.59E−01   1   Unchanged Low       O75319   H07cd3   dual specificity phosphatase 11              250.2151   205   205.1456   220.2678   −2.87E−01   −2.84E−01   1   Unchanged Low       Q9NYH9   L08ef3   hepatocellular carcinoma-associa             287.2586   283   205.223   258.6032   −4.85E−01   −1.99E−02   1   Unchanged Low       Q9UNF0   M20cd7   protein kinase C and casein kina             438.5503   349   205.53   331.0599   −1.09E+00   −3.29E−01   1   Unchanged Low       O60437   D03ab8   periplakin   443.9882   301   205.5879   316.8358   −1.11E+00   −5.61E−01   1   Unchanged Low       Q9NZN8   N22cd8   CCR4-NOT transcription comple             189.665   224   205.673   206.5153   1.17E−01   2.41E−01   1   Unchanged Low       Q14232   A18ab4   eukaryotic translation initiation fa             273.7271   210   205.7436   229.9659   −4.12E−01   −3.79E−01   1   Unchanged Low       O00142   C03ef5   thymidine kinase 2; mitochondria   124.7128   147   205.9951   159.1674   7.24E−01   2.35E−01   1   Unchanged Low       O60443   N15ab5   deafness; autosomal dominant 5   122.4035   264   208.3187   197.4327   7.53E−01   1.11E+00   1   Unchanged Low       O95406   J20cd5   cornichon-like   181.7181   138   206.4442   175.4375   1.84E−01   −3.95E−01   1   Unchanged Low       Q12841   E24cd7   follistatin-like 1   80.93058   97.7   206.5097   128.3877   1.35E+00   2.72E−01   1   Unchanged Low       O15217   B04ab5   glutathione S-transferase A4   78.38055   91.3   206.6118   125.424   1.40E+00   2.20E−01   1   Unchanged Low       P10645   E01ab4   chromogranin A (parathyroid sec   115.7467   283   206.8714   201.8922   8.38E−01   1.29E+00   1   Unchanged Low       Q9HA68   D09gh5   G protein beta subunit-like   198.1992   192   206.9573   199.1923   6.24E−02   −4.27E−02   1   Unchanged Low       Q9Y439   B06ef8   PRP31 pre-mRNA processing fa             175.7234   310   207.0904   230.9065   2.37E−01   8.19E−01   1   Unchanged Low       Q9Y386   G08ef2   CGI-78 protein   325.6509   246   207.7702   259.7061   −6.48E−01   −4.06E−01   1   Unchanged Low       P53990   D21gh1   KIAA0174 gene product   230.1187   401   207.9831   279.676   −1.46E−01   8.01E−01   1   Unchanged Low       O95865   O11ef3   dimethylarginine dimethylaminoh   125.0105   157   208.0048   163.3476   7.35E−01   3.29E−01   1   Unchanged Low           B21ef1   immunoglobulin lambda-like poly   142.7367   230   208.1338   193.5142   5.44E−01   6.86E−01   1   Unchanged Low       Q15834   I17cd7   hepatitis delta antigen-interacting   320.7647   226   208.1753   251.6031   −6.24E−01   −5.06E−01   1   Unchanged Low       P18846   H05ab4   activating transcription factor 1   470.9776   206   208.3404   295.2222   −1.18E+00   −1.19E+00   1   Unchanged Low       Q14349   A23cd7   HLA-B associated transcript 8   138.8938   175   208.5984   174.3142   5.87E−01   3.37E−01   1   Unchanged Low       Q9NVM5   M08gh3   hypothetical protein FLJ10637   98.19923   115   209.0315   140.794   1.09E+00   2.30E−01   1   Unchanged Low       P12955   N18ab7   peptidase D   133.8157   192   209.0325   178.2362   6.43E−01   5.20E−01   1   Unchanged Low       Q99700   D14cd1   spinocerebellar ataxia 2 (olivopo             191.0044   240   209.0555   213.1956   1.30E−01   3.27E−01   1   Unchanged Low       Q9UJA2   E21gh3   chromosome 20 open reading fra             134.2553   316   209.227   219.8275   6.40E−01   1.23E+00   1   Unchanged Low       Q02246   J21ef6   contactin 2 (axonal)   108.0043   68.8   209.3915   128.7469   9.55E−01   −6.50E−01   1   Unchanged Low       P48553   E06cd2   transmembrane protein 1   148.0375   238   209.4168   198.4177   5.00E−01   6.84E−01   1   Unchanged Low       Q99639   K03cd2   suppressor of Ty 5 homolog (S.              225.1962   296   209.795   243.5051   −1.02E−01   3.92E−01   1   Unchanged Low       Q9NQX5   N02gh4   neural proliferation; differentiatio             188.0695   206   209.8245   201.225   1.58E−01   1.30E−01   1   Unchanged Low       Q99799   O08cd6   nuclear RNA export factor 1   205.4132   175   209.9237   196.7655   3.13E−02   −2.32E−01   1   Unchanged Low       Q9BZV1   J05gh7   UBX domain-containing 1   127.7069   236   209.9733   191.2074   7.17E−01   8.86E−01   1   Unchanged Low       Q03113   M19ab5   guanine nucleotide binding prote             140.2412   112   209.9975   154.1344   5.82E−01   −3.22E−01   1   Unchanged Low       P01130   B21ab6   low density lipoprotein receptor (             301.1179   394   210.369   301.7776   −5.17E−01   3.87E−01   1   Unchanged Low       Q9UHN6   L11cd8   transmembrane protein 2   182.3012   130   210.5088   174.2344   2.08E−01   −4.89E−01   1   Unchanged Low       Q99738   A03cd3   pinin; desmosome associated pr             200.7164   204   210.6944   205.0214   7.00E−02   2.10E−02   1   Unchanged Low       Q9Y576   N03ef2   ankyrin repeat and SOCS box-cc   121.1139   76.2   210.8606   136.0527   8.00E−01   −6.69E−01   1   Unchanged Low       P02304   B03gh6   H4 histone; family 2   81.15302   191   210.8651   161.1406   1.38E+00   1.24E+00   1   Unchanged Low       P01118   I08ab7   v-KI-ras2 Kirsten rat sarcoma 2 v             209.4177   239   211.0234   219.9522   1.10E−02   1.93E−01   1   Unchanged Low       P15924   K13ef7   desmoplakin (DPI; DPII)   249.9083   263   211.0334   241.3819   −2.44E−01   7.48E−02   1   Unchanged Low       O43597   A19cd6   sprouty homolog 2 ( Drosophila )   119.5051   155   211.0573   161.8627   8.21E−01   3.75E−01   1   Unchanged Low       P09622   I06ab3   dihydrolipoamide dehydrogenas             346.3029   232   211.1679   263.2128   −7.14E−01   −5.77E−01   1   Unchanged Low       Q08257   G16ef7   crystallin; zeta (quinone reducta             514.6998   301   211.6448   345.4839   −1.28E+00   −7.73E−01   1   Unchanged Low       Q9UHY8   J09cd7   fasciculation and elongation pro             86.8735   95.1   211.8371   131.2705   1.29E+00   1.31E−01   1   Unchanged Low       P10646   P23cd2   tissue factor pathway inhibitor (li             596.8869   458   212.0146   422.403   −1.49E+00   −3.81E−01   1   Unchanged Low       Q92685   L08cd5   Not56 ( D. melanogaster )-like pro   195.2017   217   212.2397   208.1394   1.21E−01   1.53E−01   1   Unchanged Low       P34949   I13ab7   mannose phosphate isomerase   102.2281   135   212.3424   149.8251   1.05E+00   4.00E−01   1   Unchanged Low       Q9NPE9   M21ef8   HSPC055 protein   91.56792   157   212.3544   153.7649   1.21E+00   7.81E−01   1   Unchanged Low       Q99853   J24ef7   forkhead box B1   141.4272   105   212.4773   153.0918   5.87E−01   −4.25E−01   1   Unchanged Low       Q9HD41   C24gh4   CHMP1.5 protein   280.2988   230   212.8608   241.047   −3.97E−01   −2.85E−01   1   Unchanged Low       Q16625   A10ab8   occludin   859.5688   338   212.9222   470.2634   −2.01E+00   −1.35E+00   1   Unchanged Low       P45973   L18ef6   chromobox homolog 5 (HP1 alph             164.9514   124   213.1315   167.3186   3.70E−01   −4.13E−01   1   Unchanged Low       Q9NVI9   O12gh3   hypothetical protein FLJ10707   136.0971   136   213.1484   161.8885   6.47E−01   3.42E−03   1   Unchanged Low       P37173   O09ef7   transforming growth factor; beta              112.4415   208   213.3211   178.0564   9.24E−01   8.90E−01   1   Unchanged Low       Q9UKF7   O21cd8   retinal degeneration B beta   333.6061   287   213.5389   277.9863   −6.44E−01   −2.18E−01   1   Unchanged Low       P16870   J23ef7   carboxypeptidase E   81.85341   137   213.5973   144.0377   1.38E+00   7.40E−01   1   Unchanged Low       P00374   D16ab3   dihydrofolate reductase   148.8142   59.6   213.6217   140.6638   5.22E−01   −1.32E+00   1   Unchanged Low       P19957   M04ab8   protease inhibitor 3; skin-dervied   202.9357   582   213.9068   333.0661   7.60E−02   1.52E+00   1   Unchanged Low       O75962   J24cd2   triple functional domain (PTPRF   233.7849   197   213.9409   215.0154   −1.28E−01   −2.45E−01   1   Unchanged Low       P16050   C24ab2   arachidonate 15-lipoxygenase   288.5504   87.3   213.9824   196.6194   −4.31E−01   −1.72E+00   1   Unchanged Low       Q9Y3D2   N14cd7   pilln-like transcription factor   200.9397   224   214.0069   213.0068   9.09E−02   1.57E−01   1   Unchanged Low       O00505   J16ab6   karyopherin alpha 3 (impartin alp             358.8945   313   214.0819   295.4165   −7.45E−01   −1.96E−01   1   Unchanged Low       Q9NZD8   N15ef1   acid cluster protein 33   222.816   223   214.2958   220.0079   −5.62E−02   6.21E−04   1   Unchanged Low       P46937   G10cd6   Yes-associated protein 1; 65 kD   219.0427   268   214.3846   233.924   −3.10E−02   2.93E−01   1   Unchanged Low       P53384   O05ab7   nucleotide binding protein 1 (Min   272.4995   223   214.5051   236.5867   −3.45E−01   −2.91E−01   1   Unchanged Low       Q9UI28   K10ef4   AD-003 protein   120.4834   147   214.7067   160.6424   8.34E−01   2.84E−01   1   Unchanged Low       Q14851   O20ab8   plastin 1 (I isoform)   517.7448   303   214.7993   345.2493   −1.27E+00   −7.72E−01   1   Unchanged Low       P10914   K01ef6   Interferon regulatory factor 1   310.699   395   214.9514   306.8604   −5.32E−01   3.46E−01   1   Unchanged Low       P212B1   A03ab3   ATPase; H+ transporting; lysoso             299.07   638   215.0012   383.914   −4.76E−01   1.09E+00   1   Unchanged Low       P53701   G19ab6   holocytochrome c synthase (cyto             251.8825   415   215.1177   293.8906   −2.28E−01   7.19E−01   1   Unchanged Low       Q9Y2B1   C18ef3   transmembrane protein 5   103.4737   123   215.2492   147.2535   1.06E+00   2.50E−01   1   Unchanged Low       Q14166   D23ef8   KIAA0153 protein   332.5834   276   215.4465   274.7657   −8.26E−01   −2.68E−01   1   Unchanged Low       Q15738   B09ef4   NAD(P) dependent steroid dehyd             253.061   171   215.5558   213.0647   −2.31E−01   −5.69E−01   1   Unchanged Low       Q16586   I06cd1   sarcoglycan; alpha (50 kD dystro             358.221   129   215.8058   234.3861   −7.31E−01   −1.47E+00   1   Unchanged Low       Q9Y6J8   L05ef2   map kinase phosphatase-like pr             275.0054   326   215.9987   272.4953   −3.48E−01   2.48E−01   1   Unchanged Low       Q9H5F2   P17gh5   hypothetical protein FLJ23499   204.1242   332   216.1178   250.8425   8.24E−02   7.03E−01   1   Unchanged Low       Q05655   E02cd1   protein kinase C; delta   419.7056   297   216.1184   310.8344   −9.58E−01   −5.00E−01   1   Unchanged Low       Q9NXU7   M03gh3   hypothetical protein FLJ20048   240.4802   235   216.1338   230.6008   −1.54E−01   −3.21E−02   1   Unchanged Low       O15498   P21cd6   SNARE protein Ykt6   188.9561   242   216.7243   215.7355   1.98E−01   3.54E−01   1   Unchanged Low       Q92664   F07ab4   general transcription factor IIIA   318.1862   193   216.7575   242.5829   −5.54E−01   −7.23E−01   1   Unchanged Low       Q9Y223   N03cd5   UDP-N-acetylglucosamine-2-epi             207.311   295   217.1156   239.9817   8.67E−02   5.11E−01   1   Unchanged Low       O95816   E21ab3   BCL2-associated athanogene 2   84.7224   94.2   217.4827   132.1461   1.36E+00   1.53E−01   1   Unchanged Low       Q9H0K5   A21gh8   hypothetical protein DKFZp434H   193.1934   324   217.6924   244.8706   1.72E−01   7.45E−01   1   Unchanged Low       Q9BTJ1   C03ef2   ribosomal protein S27-like   132.1497   411   218.2702   253.7125   7.24E−01   1.64E+00   1   Unchanged Low       Q9NRR5   J23gh4   chromosome 1 open reading fra             138.2192   201   218.4149   185.8791   6.60E−01   5.40E−01   1   Unchanged Low       Q9Y5L3   A13ab4   ectonucleoside triphosphate dip             235.2745   316   218.4547   256.4569   −1.07E−01   4.24E−01   1-   Unchanged Low       O75351   K06cd5   suppressor of K+ transport defec   274.5936   311   218.6389   267.9692   −3.29E−01   1.78E−01   1   Unchanged Low       O75443   F07cd2   tectorin alpha   183.4591   150   218.7282   184.2202   2.54E−01   −2.86E−01   1   Unchanged Low       Q9H7X4   K04gh7   KIAA1085 protein   268.2576   372   218.7527   286.2489   −2.94E−01   4.71E−01   1   Unchanged Low       O00255   K22ab6   multiple endocrine neoplasia I   134.7209   117   218.9335   156.9374   7.01E−01   −2.02E−01   1   Unchanged Low       Q9BV94   D05gh3   chromosome 20 open reading fra             319.259   316   219.2324   284.912   −5.42E−01   −1.37E−02   1   Unchanged Low       O14813   D10ab2   aristaless homeobox ( Drosophila     226.3067   320   219.2567   255.131   −4.57E−02   4.99E−01   1   Unchanged Low       P35269   D15ab4   general transcription factor IIF; p   243.8395   213   219.8975   225.4377   −1.49E−01   −1.98E−01   1   Unchanged Low       Q12891   E08ef5   hyaluronoglucosaminidase 2   331.3833   311   220.4462   287.6363   −5.88E−01   −9.12E−02   1   Unchanged Low       O15162   L08gh1   phospholipid scramblase 1   440.6448   597   220.6688   419.5068   −9.98E−01   4.39E−01   1   Unchanged Low       Q14469   O08ab7   hairy homolog ( Drosophila )   151.2148   251   221.0242   207.739   5.48E−01   7.31E−01   1   Unchanged Low       P06241   P13ab4   FYN oncogene related to SRC; F   106.4214   82.5   221.2951   136.7385   1.06E+00   −3.67E−01   1   Unchanged Low       Q9BVG9   P17gh7   phosphatidylserine synthase 2   225.5812   200   221.5588   215.8454   −2.60E−02   −1.71E−01   1   Unchanged Low       Q9P0P9   K12ef2   hypothetical protein LOC51249   290.4444   434   222.6323   315.5648   −3.84E−01   5.78E−01   1   Unchanged Low       Q9UMF9   L14cd3   eukaryotic translation initiation fa   207.6515   242   222.6344   224.2505   1.01E−01   2.24E−01   1   Unchanged Low       Q03527   L07ab8   proteasome (prosome: macropai             441.6371   284   222.6794   316.1666   −9.88E−01   −6.36E−01   1   Unchanged Low       P31153   J15ab7   methionine adenosyltransferase   245.2111   134   222.7802   200.5541   −1.38E−01   −8.75E−01   1   Unchanged Low       Q04741   D21ef1   empty spiracles homolog 1 (Dros   240.3769   189   222.791   217.4148   −1.10E−01   −3.46E−01   1   Unchanged Low       Q13153   L22ef5   p21/Cdc42/Rac1-activated kinase   243.198   277   222.8583   247.6258   −1.26E−01   1.87E−01   1   Unchanged Low       Q9Y388   H15ef2   CGI-79 protein   100.7214   181   223.2467   168.2598   1.15E+00   8.44E−01   1   Unchanged Low       Q9HC14   K17gh5   mitochondrial ribosomal protein              158.7783   200   223.2594   193.9429   4.92E−01   3.31E−01   1   Unchanged Low       P30281   O08ef5   cyclin D3   107.4859   167   223.2751   166.0499   1.05E+00   6.39E−01   1   Unchanged Low       Q9UFK2   P05ef8   DKFZP564K1964 protein   133.0476   210   223.4229   188.8934   7.48E−01   6.60E−01   1   Unchanged Low       Q13011   O23ab4   enoyl Coenzyme A hydratase 1;              337.9818   273   223.7187   278.2904   −5.95E−01   −3.07E−01   1   Unchanged Low       P09601   E20ef7   heme oxygenase (decycling) 1   186.4519   425   223.7447   278.3661   2.63E−01   1.19E+00   1   Unchanged Low       Q9BVZ8   P23gh8   hypothetical protein FLJ14936   126.689   127   224.0692   159.346   8.23E−01   6.71E−03   1   Unchanged Low       Q13889   A11ab5   general transcription factor IIH: p   112.1935   202   224.1653   179.5227   9.99E−01   8.50E−01   1   Unchanged Low       P49703   P23ab2   ADP-ribosylation factor 4-like   125.6732   91.2   224.1896   147.0234   8.35E−01   −4.62E−01   1   Unchanged Low       Q9GZU7   G11gh4   nuclear LIM interactor-interacting   305.5546   150   224.2596   226.5474   −4.46E−01   −1.03E+00   1   Unchanged Low       P10253   M22ab3   glucosidase; alpha; acid (Pompe   187.3998   156   224.2782   189.0733   2.59E−01   −2.69E−01   1   Unchanged Low       Q9Y3V5   B18ef8   hypothetical protein DKFZP586F   303.8477   426   224.4103   318.1897   −4.37E−01   4.89E−01   1   Unchanged Low       O14773   P17ef7   ceroid-lipofuscinosis; neuronal 2:   169.6468   214   224.4535   202.7117   4.04E−01   3.35E−01   1   Unchanged Low       P22061   G13cd1   protein-L-isoaspartate (D-aspart             118.1783   163   224.5569   168.6387   9.26E−01   4.66E−01   1   Unchanged Low       P14868   K21ab4   aspartyl-IRNA synthetase   117.1946   78.1   225.0996   140.1468   9.42E−01   −5.85E−01   1   Unchanged Low       O14938   D16ef6   nuclear factor I/X (CCAAT-bindin   94.58773   84.9   225.3458   134.9545   1.25E+00   −1.55E−01   1   Unchanged Low       O75968   P21ef3   pannexin 1   215.9189   216   225.5368   219.072   6.29E−02   −1.06E−03   1   Unchanged Low       Q9H779   C15gh6   hypothetical protein MGC2821   138.4597   313   225.8086   225.7323   7.06E−01   1.18E+00   1   Unchanged Low       Q9BX72   C02gh8   IFP38   168.9682   172   225.8249   188.9468   4.18E−01   2.61E−02   1   Unchanged Low       O43563   G24cd1   solute carrier family 22 (organic              133.7352   149   225.8428   169.4168   7.56E−01   1.53E−01   1   Unchanged Low       O15142   D17ab2   ARP2 actin-related protein 2 ho             250.3086   215   226.0552   230.3093   −1.47E−01   −2.22E−01   1   Unchanged Low       Q9UJ41   K17ef4   putative Rab5 GDP/GTP exchan             121.9098   165   226.5205   171.2118   8.94E−01   4.38E−01   1   Unchanged Low       P05231   F21ef7   interleukin 6 (interferon; beta 2)   240.2349   673   226.529   379.972   −8.48E−02   1.49E+00   1   Unchanged Low       Q9Y2H0   G24ef8   KIAA0964 protein   279.6086   310   226.545   271.9604   −3.04E−01   1.48E−01   1   Unchanged Low       Q9UJT9   E15cd8   F-box and leucine-rich repeat por             287.9128   294   226.762   269.5315   −3.44E−01   2.98E−02   1   Unchanged Low       Q9Y306   O23ef2   pelota homolog ( Drosophila )   146.8037   190   226.8083   187.7391   6.28E−01   3.69E−01   1   Unchanged Low       Q9Y6A6   N04ef3   transcription factor (p38 interacti             174.5425   171   226.9539   190.8287   3.79E−01   −2.97E−02   1   Unchanged Low       O75300   K18cd2   ribosome binding protein 1 homo   98.67954   73.7   227.0651   133.1515   1.20E+00   −4.21E−01   1   Unchanged Low       P51798   L03ef1   chloride channel 7   278.4282   282   228.319   263.0106   −2.86E−01   1.98E−02   1   Unchanged Low       Q14839   C21ab4   chromodomain helicase DNA bin   104.8847   161   228.322   164.8091   1.12E+00   6.20E−01   1   Unchanged Low       O60299   O18gh1   KIAA0552 gene product   132.5981   337   228.426   232.6614   7.85E−01   1.35E+00   1   Unchanged Low       Q9Y6F1   H03ab2   ADP-ribosyltransferase (NAD+;              248.9844   399   228.5355   292.1577   −1.24E−01   6.80E−01   1   Unchanged Low       O15212   E04ef3   HLA class II region expressed ge             250.113   292   228.5629   256.7661   −1.30E−01   2.22E−01   1   Unchanged Low       Q9Y2W2   J14ef2   WW domain binding protein 11   335.0512   304   228.6314   289.1386   −5.51E−01   −1.42E−01   1   Unchanged Low       Q9UKN5   O03cd8   PR domain containing 4   252.6208   80.6   228.639   187.2825   −1.44E−01   −1.65E+00   1   Unchanged Low       Q00978   C24cd6   interferon-stimilated transcription   303.7171   404   228.7768   312.2774   −4.09E−01   4.13E−01   1   Unchanged Low       Q9UHY0   L08ef1   HP1-BP74   295.9512   267   228.8435   263.8122   −3.71E−01   −1.50E−01   1   Unchanged Low       Q9Y248   L13ef2   HSPC037 protein   92.39515   70.3   229.0541   130.5748   1.31E+00   −3.95E−01   1   Unchanged Low       O96019   E21ab2   BAF53   228.9673   345   229.5696   267.9206   3.79E−03   5.92E−01   1   Unchanged Low       P10276   K19ab8   retinoic acid receptor: alpha   250.0312   122   229.7466   200.7048   −1.22E−01   −1.03E+00   1   Unchanged Low       Q9BUC7   P22gh8   hypothetical protein MGC4172   136.4413   398   229.8471   254.8265   7.52E−01   1.55E+00   1   Unchanged Low       Q9HAC1   D01gh5   praja 1   143.4188   97.5   230.0154   156.9785   6.81E−01   −5.57E−01   1   Unchanged Low       Q93078   M18gh6   H2B histone family; member H   179.9656   203   230.2553   204.3058   3.56E−01   1.72E−01   1   Unchanged Low       P08572   N22ef8   collagen; type IV; alpha 2   70.14126   87.3   230.3868   129.2665   1.72E+00   3.15E−01   1   Unchanged Low       P15056   G10ef5   v-raf murine sarcoma viral oncog   194.1803   174   231.0687   199.7155   2.51E−01   −1.59E−01   1   Unchanged Low       Q15543   J15cd2   TAF13 RNA polymerase II; TAT             222.3129   262   231.2695   238.5733   5.70E−02   2.38E−01   1   Unchanged Low       O14901   J05cd3   TGFB inducible early growth res             277.9069   277   231.5621   262.1749   −2.63E−01   −4.43E−03   1   Unchanged Low           N10gh8   diphosphate dimethylallyl diphos   313.8915   257   231.841   267.6704   −4.37E−01   −2.87E−01   1   Unchanged Low       P51965   O13cd3   ubiquitin-conjugating enzyme E2   254.2693   673   232.1178   386.4499   −1.32E−01   1.40E+00   1   Unchanged Low       Q9Y3R2   G04cd8   trabsportin-SR   338.45   219   232.2301   263.1005   −5.43E−01   −6.31E−01   1   Unchanged Low       O94829   G10gh1   importin 13   160.6646   247   232.3109   213.3188   5.30E−01   6.17E−01   1   Unchanged Low       Q92859   M13ab8   neogenin homolog 1 (chicken)   153.0455   249   232.6926   211.5326   6.04E−01   7.01E−01   1   Unchanged Low       Q12846   O02cd2   syntaxin 4A (placental)   323.5547   93.2   232.9973   216.5887   −4.74E−01   −1.80E+00   1   Unchanged Low       P01286   G15ef1   growth harmone releasing hormo             237.6384   263   233.028   244.6261   −2.83E−02   1.47E−01   1   Unchanged Low       Q9UH92   L01cd8   transcription factor-like 4   172.7135   195   233.1639   200.1328   4.33E−01   1.72E−01   1   Unchanged Low       O75323   P09ab5   glioblastoma amplified sequence   178.3893   168   233.5843   193.2783   3.89E−01   −8.78E−02   1   Unchanged Low       Q9UQ33   P07ef2   microtubule-associated protein;              101.7866   134   234.2195   156.5563   1.20E+00   3.93E−01   1   Unchanged Low       Q9Y3A7   A17ef2   CGI-101 protein   402.1639   210   234.3057   282.2981   −7.79E−01   −9.34E−01   1   Unchanged Low       Q9Y2Z0   A17cd7   suppressor of G2 allele of SKP1:   184.6693   256   234.3223   224.9662   3.44E−01   4.71E−01   1   Unchanged Low       P56211   F16ab2   cyclic AMP phosphoprotein; 19 k   276.9734   386   234.3401   299.2676   −2.41E−01   4.81E−01   1   Unchanged Low       P21127   O13ef1   cell division cycle 2-like 2   159.1108   304   234.454   232.4012   5.59E−01   9.32E−01   1   Unchanged Low       Q07866   B23ab7   kinesin 2 (60-70 kD)   254.5932   408   234.5156   299.1796   −1.19E−01   6.82E−01   1   Unchanged Low       Q9BTI3   H11ef8   KIAA1068 protein   228.7025   230   234.5211   231.0835   3.62E−02   8.33E−03   1   Unchanged Low       Q9H2J4   E11gh6   hypothetical protein MGC3062   238.7573   256   235.0353   243.2412   −2.27E−02   1.00E−01   1   Unchanged Low       Q9NXE5   E10gh2   hypothetical protein FLJ20296   193.8379   399   235.1468   275.9024   2.79E−01   1.04E+00   1   Unchanged Low       Q92572   E17ab4   adaptor-related protein complex:   86.23952   209   235.2813   176.703   1.45E+00   1.27E+00   1   Unchanged Low       Q9NXT6   K05gh2   FtsJ homolog 3 ( E. coli )   254.7485   277   235.4026   255.685   −1.14E−01   1.20E−01   1   Unchanged Low       O15321   F05cd6   transmembrane 9 superfamily m             295.1129   227   235.695   252.5647   −3.24E−01   −3.79E−01   1   Unchanged Low       O15383   F07cd6   HIV-1 Tat interactive protein 2; 3             402.8554   444   235.7849   360.7235   −7.73E−01   1.39E−01   1   Unchanged Low       O60403   B06cd8   olfactory receptor; family 10; sub             237.7465   262   235.906   245.2774   −1.12E−02   1.41E−01   1   Unchanged Low       P49354   K24ab4   famesyltransferase; CAAX box;              173.9344   193   235.9155   201.1077   4.40E−01   1.54E−01   1   Unchanged Low       P48039   B07ef6   melatonin receptor 1A   305.0267   208   236.1249   249.7986   −3.69E−01   −5.51E−01   1   Unchanged Low       O43562   C08ab8   solute carrier family 22 (organic              115.4101   125   236.1587   158.9844   1.03E+00   1.20E−01   1   Unchanged Low       Q9HC89   N24ef8   calpain 10   212.0136   242   236.247   230.2337   1.56E−01   1.93E−01   1   Unchanged Low       P00790   M13ef1   pepsinogen 5; group I (pepsinog             256.009   266   236.6918   253.0491   −1.13E−01   5.77E−02   1   Unchanged Low       Q9NVP1   G01cd6   DEAD/H (Asp-Glu-Ala-Asp/His)              78.40555   89   236.7778   134.724   1.59E+00   1.83E−01   1   Unchanged Low       Q9UBN1   F23ef3   calcium channel; voltage-depend   269.9719   360   237.0557   289.0967   −1.88E−01   4.16E−01   1   Unchanged Low       P35659   M22cd3   DEK oncogene (DNA binding)   80.02159   77.8   237.1934   131.6712   1.57E+00   −4.06E−02   1   Unchanged Low       P54252   N09ef6   Machado-Joseph disease (spino             156.7549   274   237.2775   222.5126   5.98E−01   8.03E−01   1   Unchanged Low       Q14152   L12cd3   eukaryotic translation initiation fa             364.5131   268   237.302   289.959   −6.19E−01   −4.43E−01   1   Unchanged Low       Q9Y314   E16ef2   eNOS interacting protein   123.3313   219   237.3058   193.3594   9.44E−01   8.31E−01   1   Unchanged Low       Q9NRC7   E23ef3   sirtuin silent mating type informal   136.0486   328   237.5194   233.7238   8.04E−01   1.27E+00   1   Unchanged Low       P02533   N02ef6   keratin 14 (epidermolysis bullosa   203.4102   190   237.6951   210.4458   2.25E−01   −9.66E−02   1   Unchanged Low       O60907   J19cd2   transducin (beta)-like 1 X-linked   175.9553   171   237.7396   194.8701   4.34E−01   −4.19E−02   1   Unchanged Low       P43155   B16ab3   carnitine acetyltransferase   288.355   190   237.6908   238.6829   −2.78E−01   −6.03E−01   1   Unchanged Low       Q15077   H08ab8   pyrimidinergic receptor P2Y: G-p   389.9746   248   238.1475   292.1056   −7.12E−01   −6.52E−01   1   Unchanged Low       Q12840   I06ab7   kinesin family member 5A   238.3605   282   238.2407   252.8959   −7.25E−04   2.43E−01   1   Unchanged Low       P26599   A05cd3   polypyrimidine tract binding prot             160.4912   345   238.4   247.8557   5.71E−01   1.10E+00   1   Unchanged Low       Q9Y316   M11ef2   C21orf19-like protein   450.6398   327   238.5981   338.8101   −9.17E−01   −4.62E−01   1   Unchanged Low       P24394   O18ab6   interleukin 4 receptor   309.5199   330   238.6201   292.7071   −3.75E−01   9.24E−02   1   Unchanged Low       P32418   J22gh1   solute carrier family 8 (sodium/c             171.4835   134   238.7225   181.3894   4.77E−01   −3.56E−01   1   Unchanged Low       P42694   N01ef3   helicase with zinc finger domain   165.7017   146   238.7561   183.6122   5.27E−01   −1.79E−01   1   Unchanged Low       O60755   L09cd3   galanin receptor 3   162.6185   268   238.7669   223.2368   5.54E−01   7.22E−01   1   Unchanged Low       Q16204   A18cd4   DNA segment; single copy; prob             192.0586   225   238.8166   218.6477   3.14E−01   2.29E−01   1   Unchanged Low       Q12980   N15cd7   Conserved gene telomeric to alpl             183.7714   174   238.9231   198.8702   3.79E−01   −7.95E−02   1   Unchanged Low       P08559   N16ab7   pyruvate dehydrogenase (lipoam   375.1479   206   239.4879   273.612   −6.48E−01   −8.63E−01   1   Unchanged Low       Q9Y2U9   K02ef3   host cell factor homolog   127.5142   154   239.623   173.6438   9.10E−01   2.70E−01   1   Unchanged Low       Q9Y2T2   P17cd7   adaptor-related protein complex:   336.9686   395   239.6299   323.8714   −4.92E−01   2.29E−01   1   Unchanged Low       Q13105   K10cd3   zinc finger protein 151 (pHZ-67)   177.9188   243   240.018   220.1539   4.32E−01   4.47E−01   1   Unchanged Low       Q9H1J1   J12gh5   similar to yeast Upf3; variant A   154.12   183   241.0316   192.8261   6.45E−01   2.50E−01   1   Unchanged Low       Q08752   E01cd1   peptidylprolyl isomerase D (cycic             446.371   203   241.0389   296.8872   −8.89E−01   −1.13E+00   1   Unchanged Low       P38159   F14ab7   RNA binding motif protein; X ch             342.4693   176   241.0429   253.2584   −5.07E−01   −9.58E−01   1   Unchanged Low       Q9Y337   A12cd8   kallikrein 5   215.5515   312   241.2144   256.4089   1.62E−01   5.36E−01   1   Unchanged Low       P25445   A02ef6   tumor necrosis factor receptor su             102.3524   215   241.2257   186.0304   1.24E+00   1.07E+00   1   Unchanged Low       Q9BZH1   P02gh5   membrane-spanning 4-domains;   350.8825   212   241.5154   268.2725   −5.39E−01   −7.24E−01   1   Unchanged Low       O43633   O12ef4   putative breast adenocarcinoma   308.4601   232   241.573   260.7188   −3.53E−01   −4.10E−01   1   Unchanged Low       Q99536   B03cd6   vesicle amine transport protein 1   222.8504   400   241.6698   288.1564   1.17E−01   8.44E−01   1   Unchanged Low       P24557   N11cd1   thromboxane A synthase 1 (plate             326.4482   236   241.6841   268.1689   −4.34E−01   −4.66E−01   1   Unchanged Low       O75369   G16ab4   filamin B; beta (actin binding prol             331.6975   459   241.7672   344.1714   −4.56E−01   4.69E−01   1   Unchanged Low       P50453   H10ab8   serine (or cysteine) proteinase in             439.8605   370   242.4005   350.7941   −8.60E−01   −2.49E−01   1   Unchanged Low       P35680   O18cd1   transcription factor 2; hepatic; LF   235.5021   174   242.5943   217.2497   4.28E−02   −4.40E−01   1   Unchanged Low       Q03924   I01gh7   zinc finger protein 117 (HPF9)   257.8571   301   242.7729   267.2646   −8.70E−02   2.24E−01   1   Unchanged Low       Q9NRQ5   F17gh4   FN5 protein   361.924   325   242.8257   309.8867   −5.76E−01   −1.56E−01   1   Unchanged Low       Q99867   G12gh7   tubulin; beta polypeptide 4; mem   376.7361   247   243.6773   289.1694   −6.29E−01   −6.08E−01   1   Unchanged Low       Q9H682   B19gh7   A20-binding inhibitor of NF-kapp             205.6095   365   243.7949   271.5091   2.46E−01   8.28E−01   1   Unchanged Low       O00148   N12cd5   DEAD/H (Asp-Glu-Ala-Asp/His)              259.196   140   244.0023   214.3036   −8.71E−02   −8.92E−01   1   Unchanged Low           F11cd8   TCF3 (E2A) fusion partner (in ch   170.7519   295   244.0153   236.7141   5.15E−01   7.91E−01   1   Unchanged Low       Q9UG51   N05ef3   anaphase-promoting complex su   274.4079   331   244.0324   283.0875   −1.69E−01   2.70E−01   1   Unchanged Low       O75175   F12cd8   CCR4-NOT transcription comple             230.1579   253   244.0384   242.329   8.45E−02   1.35E−01   1   Unchanged Low       Q9GZQ8   C05gh2   microtubule-associated proteins   261.5987   395   244.0725   300.1702   −1.00E−01   5.94E−01   1   Unchanged Low       P19438   A04ef6   tumor necrosis factor receptor su             233.3188   197   244.3384   224.9565   6.66E−02   −2.43E−01   1   Unchanged Low       Q9NRR8   O04gh4   small protein effector 1 of Cdc42   338.2133   329   244.5729   303.9389   −4.68E−01   −3.97E−02   1   Unchanged Low       O95162   N10ef8   peroxisomal short-chain alcohol              154.9486   108   244.9155   169.1352   6.60E−01   −5.27E−01   1   Unchanged Low       O95279   J22cd3   potassium channel; subfamily K;   274.3417   127   244.9972   215.5542   −1.63E−01   −1.11E+00   1   Unchanged Low       Q9NTW4   N21ef8   DKFZP564A2416 protein   403.4188   219   245.1953   289.1446   −7.18E−01   −8.83E−01   1   Unchanged Low       Q9NWM9   H21gh2   hypothetical protein FLJ20730   121.538   207   245.69   191.4607   1.02E+00   7.69E−01   1   Unchanged Low       P40121   P23ab5   capping protein (actin filament);              452.2006   414   245.8846   370.7982   −8.79E−01   −1.26E−01   1   Unchanged Low       Q92466   I04ab3   damage-specific DNA binding pr             99.17314   220   246.0478   188.2839   1.31E+00   1.15E+00   1   Unchanged Low       O43365   K05gh7   homeo box A3   132.7369   196   246.2071   191.5647   8.91E−01   5.60E−01   1   Unchanged Low       Q9NVJ7   O02gh3   DEAD/H (Asp-Glu-Ala-Asp/His)              336.1927   284   246.3831   288.7892   −4.48E−01   −2.44E−01   1   Unchanged Low       Q9NVY5   H08ef7   serotogically defined colon canc             182.4596   178   246.7633   202.4155   4.36E−01   −3.55E−02   1   Unchanged Low       Q9BY40   G12gh8   CDA11 protein   141.0763   131   246.8975   173.0132   8.07E−01   −1.06E−01   1   Unchanged Low       Q9NZE2   O06ef2   hypothetical protein LOC51321   76.41026   135   247.0025   152.875   1.69E+00   8.23E−01   1   Unchanged Low       P29275   K11ab2   adenosine A2b receptor   354.5115   191   247.0615   264.0659   −5.21E−01   −8.95E−01   1   Unchanged Low       Q9NZE0   P22ef1   WW domain-containing adapter             82.72809   71.1   247.6094   133.8159   1.58E+00   −2.18E−01   1   Unchanged Low       Q03111   N03ab7   myeloid/lymphoid or mixed-linea             225.1377   162   247.8275   211.7891   1.39E−01   −4.71E−01   1   Unchanged Low       Q08499   G21ef6   phosphodiesterase 4D; cAMP-sp   125.5177   92.9   248.1727   155.5405   9.83E−01   −4.34E−01   1   Unchanged Low       Q15628   A20ef6   TNFRSF1A-associated via death   214.1641   250   248.2613   237.3623   2.13E−01   2.21E−01   1   Unchanged Low       Q9Y657   C07cd7   spindlin   217.9487   202   248.4185   222.9201   1.89E−01   −1.07E−01   1   Unchanged Low       Q9UHQ1   I09cd8   nuclear prelamin A recognition f             312.9614   303   248.5926   288.0624   −3.32E−01   −4.84E−02   1   Unchanged Low       P17980   H24ef6   proteasome (prosome; macropai             331.1488   193   248.6286   257.496   −4.13E−01   −7.81E−01   1   Unchanged Low       P45877   I19ab8   peptidylprolyl isomerase C (cycl             165.0716   169   248.9851   194.3167   5.93E−01   3.30E−02   1   Unchanged Low       O95340   A23cd5   3′-phosphoadenosine 5′-phosph             110.9876   88.6   249.0622   149.5355   1.17E+00   −3.26E−01   1   Unchanged Low       Q9H9Z7   F18gh5   hypothetical protein FLJ12448   158.5794   279   249.1478   228.8009   6.52E−01   8.13E−01   1   Unchanged Low       O15172   E11cd4   phosphoserine phosphatase-like   321.9068   291   249.3629   287.4495   −3.68E−01   −1.45−01   1   Unchanged Low       P01298   F05ab8   pancreatic polypeptide   544.0034   194   249.376   329.1527   −1.13+00   −1.49E+00   1   Unchanged Low       Q13395   J17cd2   TAR (HIV) RNA binding protein 1   260.7056   234   249.3777   248.0711   −6.41E−02   −1.55E−01   1   Unchanged Low       O15551   G23ab4   claudin 3   279.9519   250   249.4618   259.744   −1.66E−01   −1.64E−01   1   Unchanged Low       P55060   G20ef6   CSE1 chromosome segregation   322.1588   276   249.5903   282.6907   −3.68E−01   −2.21E−01   1   Unchanged Low       O43288   E13ab3   UDP-Gal: betaGlcNac beta 1; 4-             316.581   468   249.8072   344.9578   −3.42E−01   5.65E−01   1   Unchanged Low       P04424   J10ab2   argininosuccinate lyase   594.9833   269   250.046   371.2798   −1.25E+00   −1.15E+00   1   Unchanged Low       Q9NWR5   C10gh3   hypothetical protein FLJ20657   171.9643   252   250.1961   244.6498   5.41E−01   5.50E−01   1   Unchanged Low       Q98UN8   M21gh6   hypothetical protein MGC3067   165.6904   175   250.2847   197.0059   5.95E−01   7.92E−02   1   Unchanged Low       P49760   G01ab4   CDC-like kinase 2   69.23701   97.1   250.3266   138.8925   1.85E+00   4.88E−01   1   Unchanged Low       Q9UEG3   E01gh7   myotubularin related protein 3   367.623   236   250.553   284.5589   −5.53E−01   −6.42E−01   1   Unchanged Low       Q9P0Y6   N07ef1   chromosome 3 open reading frar   268.1158   256   250.6098   258.2636   −9.74E−02   −6.63E−02   1   Unchanged Low       Q92535   M06ab8   phosphatidylinositol glycan; clas             218.2502   172   250.9192   213.6071   2.01E−01   −3.46E−01   1   Unchanged Low       Q00577   A24gh7   purine-rich element binding prot             839.6   273   251.0214   454.6488   −1.74E+00   −1.62E+00   1   Unchanged Low       O75717   L21ab2   AND-1 protein   225.9974   250   251.1522   242.2724   1.52E−01   1.44E−01   1   Unchanged Low       P04278   L09cd1   sex hormone-binding globulin   215.6067   196   251.1944   221.0173   2.20E−01   −1.36E−01   1   Unchanged Low       P51124   G19ab5   granzyme M (lymphocyte met-as             108.9072   114   251.2498   158.1827   1.21E+00   7.09E−02   1   Unchanged Low       P15259   P04ab7   phosphoglycerate mutase 2 (mu             333.2442   363   251.6606   315.8301   −4.05E−01   1.22E−01   1   Unchanged Low       Q12893   O13cd7   PL6 protien   174.3077   280   252.0241   235.3565   5.32E−01   6.82E−01   1   Unchanged Low       P57738   A11gh2   T-cell leukemia transiocation aite   166.5683   232   252.2165   217.0429   5.99E−01   4.80E−01   1   Unchanged Low       P24863   O22ef5   cyclin C   668.8634   523   252.3632   481.4089   −1.41E+00   −3.55E−01   1   Unchanged Low       Q9Y370   H03ef2   CGI-60 protein   153.6349   157   252.5036   187.603   7.17E−01   2.82E−02   1   Unchanged Low       Q9HD89   E04gh4   found in inflammatory zone 3   189.8748   182   252.7224   208.2163   4.13E−01   −6.07E−02   1   Unchanged Low       O14807   N04cd7   muscle RAS oncogene homolog   105.1243   181   252.8147   179.5238   1.27E+00   7.81E−01   1   Unchanged Low       Q13435   I07cd7   splicing factor 3b; subunit 2; 145             270.3354   268   252.8473   263.6077   −9.65E−02   −1.45E−02   1   Unchanged Low       Q9UMY4   F19cd8   sorting nexin 12   178.8659   227   253.0138   219.6698   5.00E−01   3.45E−01   1   Unchanged Low       O43929   C04ab8   origin recognition complex; subu             267.5605   354   253.265   291.5955   −7.92E−02   4.04E−01   1   Unchanged Low       Q9BZQ1   H14gh7   chromosome 1 open reading frar   219.6632   362   253.5183   278.4192   2.07E−01   7.21E−01   1   Unchanged Low       P55042   K03ef5   Ras-related associated with diab   300.5794   514   253.5279   355.8906   −2.46E−01   7.73E−01   1   Unchanged Low       Q92870   k18ef1   amyloid beta (A4) precursor prot             76.07104   77.9   253.5714   135.8422   1.74E+00   3.40E−02   1   Unchanged Low       P33778   C19gh7   H2B histone family; member F   169.4431   391   253.9554   271.5522   5.84E−01   1.21E+00   1   Unchanged Low       Q9ULZ3   K22cd8   apoptosis-associated speck-like   255.9554   517   254.0856   342.2046   −1.06E−02   1.01E+00   1   Unchanged Low       Q13485   A20ef5   MAD; mothers against decapent             163.1373   181   254.1546   199.4935   6.40E−01   1.51E−01   1   Unchanged Low       Q9H6B4   C24gh5   zinc finger protein 335   326.6826   261   254.3385   280.5396   −3.61E−01   −3.26E−01   1   Unchanged Low       Q9H7F8   O06gh7   hypothetical protein FLJ20958   190.1073   258   254.7198   234.2579   4.22E−01   4.40E−01   1   Unchanged Low       Q92508   B17gh1   KIAA0233 gene product   241.1859   216   255.0491   237.2652   8.06E−02   −1.62E−01   1   Unchanged Low       Q9UM47   C15ab8   Notch homolog 3 ( Drosophila )   64.97745   132   255.0839   150.552   1.97E+00   1.02E+00   1   Unchanged Low       P18084   E17ef7   integrin; beta 5   259.2818   129   255.1335   214.6124   −2.33E−02   −1.00E+00   1   Unchanged Low       Q99462   K22gh6   ubiquitin-conjugating enzyme E2   207.6691   179   255.2632   213.9424   2.98E−01   −2.15E−01   1   Unchanged Low       O75619   J10ef7   RNA helicase-related protein   198.1059   335   255.6713   262.7733   3.68E−01   7.56E−01   1   Unchanged Low       Q92733   K07cd1   papillary renal cell carcinoma (tr             200.3207   260   256.1407   238.8334   3.55E−01   3.76E−01   1   Unchanged Low       Q15796   H21ab7   MAD; mothers against decapent             376.8422   446   256.2171   359.5423   −5.57E−01   2.42E−01   1   Unchanged Low       P15291   E07ab3   UDP-Gal: betaGlcNAc beta 1; 4-             411.9325   403   256.9006   357.1444   −6.81E−01   −3.31E−02   1   Unchanged Low       Q99417   I07cd8   c-myc binding protein   264.1386   256   256.9088   259.037   −4.00E−02   −4.48E−02   1   Unchanged Low       P05732   D09ab4   creatine kinase; muscle   202.527   127   257.2272   195.4365   3.45E−01   −6.78E−01   1   Unchanged Low       P50570   K13ab5   dynamin 2   248.1389   228   257.2474   244.4335   5.20E−01   −1.23E−01   1   Unchanged Low       Q9Y5A9   F20ef2   high-glucose-regulated protein 8   359.385   371   257.3917   329.2557   −4.82E−01   4.59E−02   1   Unchanged Low       Q92841   B17cd6   DEAD/H (Asp-Glu-Ala-Asp/His) t   229.8916   270   257.9255   252.4572   1.66E−01   2.30E−01   1   Unchanged Low       P51808   B22cd2             -complex-associated-testis-exp             182.2992   245   257.9487   228.2619   5.01E−01   4.24E−01   1   Unchanged Low       O95758   H23cd5   ROD1 regulator of differentiation   411.9888   462   258.1758   377.5392   −6.74E−01   1.67E−01   1   Unchanged Low       P32970   I15ef5   tumor necrosis factor (ligand) su             443.4158   456   258.4229   386.0177   −7.79E−01   4.11E−02   1   Unchanged Low       O75689   K21cd7   centaurin; alpha 1   191.7263   327   258.6362   259.1653   4.32E−01   7.71E−01   1   Unchanged Low       P55072   O06cd4   valosin-containing protein   466.7034   363   258.8411   362.8018   −8.50E−01   −3.63E−01   1   Unchanged Low       P47813   A16ab4   eukaryotic transtation initiation fa   486.6493   337   259.0481   360.7943   −9.10E−01   −5.31E−01   1   Unchanged Low       Q15532   J03cd2   synovial sarcoma translocation;              190.8535   212   259.1488   220.5805   4.41E−01   1.50E−01   1   Unchanged Low       Q15813   M19cd2   tubulin-specific chaperone              151.2337   166   259.2747   192.1296   7.78E−01   1.33E−01   1   Unchanged Low       P14373   B08cd2   ret finger protein   282.5757   270   259.3599   270.5765   −1.24E−01   −6.68E−02   1   Unchanged Low       O14980   G02cd3   exportin 1 (CRM1 homolog; yeas   239.4965   207   259.7187   235.5264   1.17E−01   −2.08E−01   1   Unchanged Low       P07942   P20ef6   laminin; beta 1   71.03574   92.4   259.7579   141.0764   1.87E+00   3.80E−01   1   Unchanged Low       P53041   C20cd1   protein phosphatase 5; catalytic              272.5094   196   259.8138   242.7533   −6.88E−02   −4.76E−01   1   Unchanged Low       Q07820   E12ef6   myetoid cell leukemia sequence   362.5007   243   260.0329   288.4688   −4.79E−01   −5.78E−01   1   Unchanged Low       P53816   E04cd7   HRAS-like suppressor 3   606.0957   558   260.1565   474.8201   −1.22E+00   −1.19E−01   1   Unchanged Low       Q9P1C8   E09gh4   hypothetical protien PRO2577   238.9909   205   260.3147   234.8631   1.23E−01   −2.19E−01   1   Unchanged Low       P51968   O21cd3   ubiquitin-conjugating enzyme E2   148.3528   243   260.3185   217.1092   8.11E−01   7.10E−01   1   Unchanged Low       Q99739   M03cd7   plm-2 oncogene   178.694   274   260.4482   237.5556   5.44E−01   6.14E−01   1   Unchanged Low       P35913   N14ab7   phosphodiesterase 6B; cGMP-s             199.3654   173   260.5708   210.8879   3.86E−01   −2.07E−01   1   Unchanged Low       P52756   J24cd5   RNA binding motif protein 5   280.6537   230   261.0637   257.2441   −1.04E−01   −2.87E−01   1   Unchanged Low       Q9NXX5   K17gh3   hypothetical protein FLJ20004   130.163   197   261.2642   196.0576   1.01E+00   5.96E−01   1   Unchanged Low       Q14498   O06cd5   RNA-binding region (RNP1; RR             196.0463   216   261.5829   224.4664   4.16E−01   1.38E−01   1   Unchanged Low       P28069   A03ab8   POU domain; class 1; transcripti             261.1822   206   261.7763   243.064   3.28E−03   −3.41E−01   1   Unchanged Low       P51397   E20ab5   death-associated protein   348.1009   312   261.9342   307.4499   −4.10E−01   −1.57E−01   1   Unchanged Low       Q9NUI8   C24gh7   putative methyltransferase   157.3551   329   262.0287   249.4637   7.36E−01   1.06E+00   1   Unchanged Low       O00322   M09cd7   uroplakin 1A   223.5286   295   262.0828   260.1175   2.30E−01   3.99E−01   1   Unchanged Low       P78368   I09ab4   casein kinase 1; gamma 2   211.1048   272   262.1137   248.257   3.12E−01   3.63E−01   1   Unchanged Low       Q01081   I22cd4   U2(RNU2) small nuclear RNA au   138.1533   91.3   262.1811   163.878   9.24E−01   −5.98E−01   1   Unchanged Low       O43193   J15ab5   G protein-coupled receptor 38   69.57316   208   262.301   179.1305   1.91E+00   1.56E+00   1   Unchanged Low       Q9Y3B0   M03ef2   CGI-105 protein   174.5026   177   262.5458   204.6742   5.89E−01   2.03E−02   1   Unchanged Low       Q9NV80   H05gh3   WD repeat domain 12   178.5139   279   262.6286   239.9609   5.57E−01   6.43E−01   1   Unchanged Low       Q9Y473   O18cd4   zinc finger protein 175   141.3794   275   263.1099   226.3406   8.96E−01   9.57E−01   1   Unchanged Low       Q9Y548   L20gh2   hypothetical protein DJ167A19.1   233.5442   240   263.4412   245.7773   1.74E−01   4.14E−02   1   Unchanged Low       Q13952   N15ef6   nuclear transcription factor Y; ga   241.7469   354   263.6055   286.4173   1.25E−01   5.50E−01   1   Unchanged Low       P18815   K17cd3   RD RNA-binding protein   237.0199   242   263.7642   247.7362   1.54E−01   3.25E−02   1   Unchanged Low       P33241   B23ef1   lymphocyte-specific protein 1   94.80267   131   264.242   163.4955   1.48E+00   4.71E−01   1   Unchanged Low       O15116   C01ef4   Lsm1 protein   344.8146   479   264.6979   362.8572   −3.81E−01   4.74E−01   1   Unchanged Low       P50897   A11ab8   palmitoyl-protein thioesterase 1 (   126.6311   142   264.8236   177.9418   1.06E+00   1.69E−01   1   Unchanged Low           F20gh8   MADP-1 protein   134.6124   228   264.9564   209.3298   9.77E−01   7.63E−01   1   Unchanged Low       Q9Y3A5   G12ef2   CGI-97 protein   469.4567   544   265.0744   426.2946   −8.25E−01   2.14E−01   1   Unchanged Low       Q9BVT1   G03gh6   leukocyte receptor cluster (LRC)   282.5457   328   265.5443   291.9599   −8.95E−02   2.14E−01   1   Unchanged Low       Q9UM44   E10cd7   HERV-H LTR-associating 2   180.7238   119   265.5625   188.5666   5.55E−01   −5.98E−01   1   Unchanged Low       Q9UGC7   A05gh3   similar to prokaryotic-type Class I   289.9756   362   265.7778   306.0797   −1.26E−01   3.22E−01   1   Unchanged Low       P49146   G01ab8   neuropeptide Y receptor Y2   222.0084   57.8   265.9266   181.9126   2.60E−01   −1.94E+00   1   Unchanged Low       P54687   I03ab3   branched chain aminotransferas             103.4218   93.8   266.0547   154.4299   1.36E+00   −1.41E−01   1   Unchanged Low       O60884   O09cd6   DnaJ (Hsp40) homolog; subfamil             330.3137   367   266.0819   321.0577   −3.12E−01   1.51E−01   1   Unchanged Low       Q9NVC6   J01cd7   cofactor required for Sp1 transcri   183.0562   150   266.1556   199.8392   5.40E−01   −2.84E−01   1   Unchanged Low       O43399   G06cd2   tumor protein D52-like 2   283.4636   348   266.2168   299.1558   −9.06E−02   2.95E−01   1   Unchanged Low       O75880   K22cd2   SCO cytochrome oxidase deficie   156.7184   117   266.2419   179.8238   7.65E−01   −4.28E−01   1   Unchanged Low       P49406   F01gh1   mitochondrial ribosomal protein              577.0339   353   266.3918   398.6973   −1.12E+00   −7.10E−01   1   Unchanged Low       Q9NYK5   E15gh2   mitochondrial ribosomal protein              473.2712   449   266.7642   396.3322   −8.27E−01   −7.61E−02   1   Unchanged Low       O15428   P18cd2   protein (peptidyl-prolyl cls/trans              185.1313   249   267.1449   233.6377   5.29E−01   4.25E−01   1   Unchanged Low       O14842   K04ab5   G protein-coupled receptor 40   222.6002   170   267.4241   219.8563   2.65E−01   −3.93E−01   1   Unchanged Low       O15262   I06cd6   ring finger protein 3   243.845   401   267.4275   304.1323   1.33E−01   7.18E−01   1   Unchanged Low       Q9NP61   J01ef3   ADP-ribosylation factor GTPase             344.6989   175   267.443   262.4544   −3.66E−01   −9.76E−01   1   Unchanged Low       O15491   P22cd5   WD-repeat protein   254.6168   355   267.6951   292.4461   7.23E−02   4.80E−01   1   Unchanged Low       O75390   P01ab5   citrate synthase   656.561   312   268.0488   412.1526   −1.29E+00   −1.07E+00   1   Unchanged Low       P57088   I12gh3   hypothetical protein FLJ10525   377.5067   349   268.1833   331.588   −4.93E−01   −1.13E−01   1   Unchanged Low       Q9NRY6   K06gh4   phospholipid scramblase 3   272.0774   334   268.2248   291.4542   −2.06E−02   2.96E−01   1   Unchanged Low       O15403   E05cd5   solute carrier family 16 (monocar   384.2992   73.5   268.3423   242.0422   −5.18E−01   −2.39E+00   1   Unchanged Low       Q9BPZ5   K09gh6   hypothetical protein MGC3123   127.3745   286   268.7928   227.363   1.08E+00   1.17E+00   1   Unchanged Low       P10301   P01cd2   related RAS viral (r-ras) oncog             314.4978   204   268.8367   262.4726   −2.26E−01   −6.24E−01   1   Unchanged Low           A20gh7   HLA-B associated transcript 4   168.0802   234   269.0656   223.8166   6.79E−01   4.79E−01   1   Unchanged Low       Q9P018   A08ef8   HSPC142 protein   196.1899   346   269.5447   270.6564   4.58E−01   8.20E−01   1   Unchanged Low       Q9Y4H2   L10cd3   Insulin receptor substrate 2   297.029   329   270.4962   298.8227   −1.35E−01   1.47E−01   1   Unchanged Low       Q9UJX3   F04ef2   anaphase-promoting complex su   210.2906   204   270.642   228.4449   3.64E−01   −4.10E−02   1   Unchanged Low       Q9H5X0   O01gh6   hypothetical protein MGC2941   333.5834   308   270.759   304.1289   −3.01E−01   −1.15E−01   1   Unchanged Low       Q92820   H23cd4   gamma-glutamyl hydrolase (conj             78.13783   101   271.925   150.359   1.80E+00   3.70E−01   1   Unchanged Low       Q9UKK3   K15ab2   ADP-ribosyltransferase (NAD+;              337.297   450   271.9944   352.9975   −3.10E−01   4.15E−01   1   Unchanged Low       Q9NWC8   N13gh2   hypothetical protein FLJ10120   315.7654   301   272.0013   296.1206   −2.15E−01   −7.10E−02   1   Unchanged Low       O14965   I07cd2   serine/threonine kinase 6   139.2727   101   272.158   170.6789   9.67E−01   −4.69E−01   1   Unchanged Low       P50613   B11ef5   cyclin-dependent kinase 7 (MO1             286.8535   423   272.2018   327.4234   −7.56E−02   5.61E−01   1   Unchanged Low       Q9H1C4   H08gh7   unc-93 homolog B1 ( C. elegans )   348.8713   501   272.3385   374.1085   −3.57E−01   5.22E−01   1   Unchanged Low       P21851   E13ab4   adaptor-related protein complex              338.7753   373   272.4617   328.1045   −3.14E−01   1.39E−01   1   Unchanged Low       Q9UGJ0   B14ef2   protein kinase; AMP-activated; g             425.3015   543   272.5312   413.4782   −6.42E−01   3.51E−01   1   Unchanged Low       P04035   D17ab6   3-hydroxy-3-methylglutaryl-Coen   242.9132   169   273.2324   228.5315   1.70E−01   −5.20E−01   1   Unchanged Low       Q9UKY7   K03gh3   hypothetical protein H41   643.0085   272   273.736   396.2551   −1.23E+00   −1.24E+00   1   Unchanged Low       O95478   B18gh1   hypothetical protein YR-29   248.2059   221   273.8047   247.5607   1.42E−01   1.70E−01   1   Unchanged Low       Q9Y3W9   B16ef8   sentrin/SUMO-specific protease              220.4064   333   274.1753   275.7642   3.15E−01   5.94E−01   1   Unchanged Low       Q9Y325   A20ef2   CGI-36 protein   346.618   338   274.2434   319.4542   −3.38E−01   −3.85E−02   1   Unchanged Low       Q92854   B09cd6   sema domain; immunoglobulin d             342.6474   183   274.4146   266.8232   −3.20E−01   −9.02E−01   1   Unchanged Low       P16106   O08gh6   H3 histone family; member C   105.4744   221   274.8424   200.5879   1.38E+00   1.07E+00   1   Unchanged Low       O43143   M05ab4   DEAD/H (Asp-Glu-Ala-Asp/His)              412.7015   349   274.9731   345.6042   −5.86E−01   −2.41E−01   1   Unchanged Low       Q13547   L12ef6   histone deacetylase 1   375.5725   372   275.2293   340.9663   −4.48E−01   −1.34E−02   1   Unchanged Low       Q9H6F9   D11gh5   hypothetical protein FLJ22313   306.5811   290   275.269   290.6336   −1.55E−01   −8.00E−02   1   Unchanged Low       O9NX18   M08gh2   hypothetical protein FLJ20487   311.71   394   275.6418   327.1007   −1.77E−01   3.38E−01   1   Unchanged Low       O94764   P03cd5   RAN binding protein 9   256.3223   268   275.8144   266.5947   1.06E−01   6.24E−02   1   Unchanged Low       P82909   N18gh8   mitochondrial ribosomal protein              261.4618   343   275.8463   293.6016   7.73E−02   3.94E−01   1   Unchanged Low       Q9UI07   D18ef8   likely ortholog of mouse heal sh             199.8914   199   276.061   225.0966   4.66E−01   −4.00E−03   1   Unchanged Low       P20337   M01ef5   RAB3B; member RAS oncogene   214.8304   126   276.148   205.8132   3.62E−01   −7.65E−01   1   Unchanged Low       Q07960   B22ab2   Rho GTPase activating protein              219.98   218   276.184   237.9303   3.28E−01   −1.55E−02   1   Unchanged Low       P49448   P03cd7   Glutamate dehydrogenase-2   344.3683   229   276.2751   283.2713   −3.18E−01   −5.88E−01   1   Unchanged Low       Q9NX48   K08gh2   hypothetical protein FLJ20442   493.7568   601   276.8343   457.1855   −8.35E−01   2.83E−01   1   Unchanged Low       Q9NV56   J03gh3   chromosome 20 open reading fr             138.9543   104   277.4945   173.6478   9.98E−01   −4.11E−01   1   Unchanged Low       O00154   L21cd7   brain acyl-CoA hydrolase   173.5669   189   277.5737   213.4547   6.77E−01   1.25E−01   1   Unchanged Low       Q9UI70   B04ef1   nucleolar protein ANKT   307.7657   349   277.6076   311.4328   −1.49E−01   1.81E−01   1   Unchanged Low       P26045   N17ab8   protein tyrosine phosphatase; no   412.292   315   277.6603   334.8518   −5.70E−01   −3.90E−01   1   Unchanged Low       Q9Y2A8   C24ef3   CD209 antigen-like   72.21222   91.3   277.8103   147.0989   1.94E+00   3.38E−01   1   Unchanged Low       Q9BZ89   F08gh7   phospholipase A2; group XII   175.384   216   277.9804   223.0558   6.64E−01   2.99E−01   1   Unchanged Low       P35052   J24ab4   glypican 1   214.4355   173   278.2085   221.7567   3.76E−01   −3.13E−01   1   Unchanged Low       Q9H0S9   K21gh7   nuclear receptor binding factor-2   80.19669   155   278.4321   171.2074   1.80E+00   9.51E−01   1   Unchanged Low       Q15654   I07ef7   thyroid hormone receptor interac             264.295   238   278.8016   260.4802   7.71E−02   −1.49E−01   1   Unchanged Low       P51946   I09ab7   manage a trois 1 (CAK assembly   239.1769   272   278.9368   263.2799   2.22E−01   1.84E−01   1   Unchanged Low       Q13133   B20cd5   nuclear receptor subfamily 1; gro             276.5554   260   279.1408   272.0232   1.34E−02   −8.70E−02   1   Unchanged Low       Q9P0J9   H22gh3   goliath protein   337.3229   215   279.5646   277.1331   −2.71E−01   −6.53E−01   1   Unchanged Low       Q15546   G23cd8   monocyte to macrophage differe             136.5038   94   279.6415   170.0401   1.03E+00   −5.39E−01   1   Unchanged Low       P28325   E09ab5   cystatin D   371.6792   309   279.7092   320.2206   −4.10E−01   −2.65E−01   1   Unchanged Low       O94985   O04ef8   calsyntenin 1   137.0471   205   279.921   207.2587   1.03E+00   5.80E−01   1   Unchanged Low       P48634   M03cd4   HLA-B associated transcript 2   266.8369   179   280.5497   241.9692   7.23E−02   −5.80E−01   1   Unchanged Low       Q9BRL6   O15gh7   Splicing factor; arginine/serine-             220.3804   304   280.5881   268.4079   3.48E−01   4.65E−01   1   Unchanged Low       O94851   E06gh1   KIAA0750 gene product   108.6672   172   280.9738   187.2889   1.37E+00   6.64E−01   1   Unchanged Low       Q9NW56   E20gh3   hypothetical protein FLJ10305   240.4538   314   281.002   278.4551   2.25E−01   3.85E−01   1   Unchanged Low       Q9H6X6   P19gh5   CasL interacting molecule   183.3739   302   281.185   255.4932   6.17E−01   7.19E−01   1   Unchanged Low       P41217   N13ab7   antigen identified by monoclonal   325.1642   166   281.3505   257.5072   −2.09E−01   −9.70E−01   1   Unchanged Low       P31512   P04ab4   flavin containing monooxygenas             192.4074   276   281.6555   249.9252   5.50E−01   5.19E−01   1   Unchanged Low       Q15425   H05cd2   SA hypertention-associated hor             186.2766   151   281.9205   206.4709   5.98E−01   −3.01E−01   1   Unchanged Low       P40306   L05ab8   proteasome (prosome; macropai             408.3043   513   281.9429   400.975   −5.34E−01   3.28E−01   1   Unchanged Low       Q9NWZ8   O02gh2   hypothetical protein FLJ20514   287.569   146   281.9498   238.3826   −2.65E−02   −9.82E−01   1   Unchanged Low       P57073   E22ef8   SRY (sex determining region Y)             202.5886   268   281.9705   251.002   4.77E−01   4.06E−01   1   Unchanged Low       Q9Y450   H22cd6   HBS1-like ( S. cerevisiae )   230.8266   312   282.4288   274.9973   2.91E−01   4.34E−01   1   Unchanged Low       P04062   O08ab3   glucosidase; beta; acid (includes   295.5318   389   282.6453   322.2918   −6.43E−02   3.95E−01   1   Unchanged Low       O75065   E22gh1   phosphodiesterase 4D interactin             168.0201   154   282.6456   201.6823   7.50E−01   −1.22E−01   1   Unchanged Low       Q9ULX2   F09ef3   NIMA (never in mitosis gene a)             288.5578   208   283.1715   259.9871   −2.72E−02   −4.71E−01   1   Unchanged Low       Q99871   C06ef4   three prime repair exonuclease 2   205.6083   225   283.2504   237.9088   4.62E−01   1.29E−01   1   Unchanged Low       Q93065   I15cd6   PER811 family member in MHC              295.7132   457   283.4269   345.3524   −6.12E−02   6.28E−01   1   Unchanged Low       O43837   B12ab7   isocitrate dehydrogenase 3 (NA             348.9961   296   283.6422   310.0846   −2.99E−01   −2.30E−01   1   Unchanged Low       Q9H9L3   L06gh7   hypothetical protein FLJ12671   209.5906   279   283.6912   257.4051   4.37E−01   4.12E−01   1   Unchanged Low       Q13740   A18ab2   activated leucocyte cell adhesio             231.4555   253   283.7582   256.0277   2.94E−01   1.28E−01   1   Unchanged Low       Q12888   L09cd2   tumor protein p53 binding protei             132.9276   223   283.8572   213.3434   1.09E+00   7.48E−01   1   Unchanged Low       P78318   J13ab6   immunoglobulin (CD79A) binding   423.8715   512   283.9511   406.4772   −5.78E−01   2.71E−01   1   Unchanged Low       P48436   K24cd1   SRY (sex determining region Y)-             345.2087   197   284.0786   275.3736   −2.81E−01   −8.10E−01   1   Unchanged Low       P18065   B19ef1   insulin-like growth factor binding   286.6516   283   284.2331   264.4952   −1.22E−02   −2.05E−02   1   Unchanged Low       Q9ULW6   F22cd8   nucleosome assembly protein 1-             223.0694   148   284.717   218.587   3.52E−01   −5.92E−01   1   Unchanged Low       O95154   N03cd7   aldo-keto reductase family 7; me             299.9079   298   284.8919   294.419   −7.41E−02   −7.00E−03   1   Unchanged Low       O95169   P14ab8   NADH dehydrogenase (ubiquino             374.2624   199   285.0096   286.0758   −3.93E−01   −9.12E−01   1   Unchanged Low       Q99982   C24ef4   XIAP associated factor-1   63.10609   116   285.0252   154.8111   2.18E+00   8.82E−01   1   Unchanged Low       Q99470   F14cd2   stromal cell-derived factor 2   230.3684   316   285.1394   277.1416   3.08E−01   4.56E−01   1   Unchanged Low       P16104   N19ab5   H2A histone family; member X   234.8351   195   285.2056   238.3532   2.80E−01   −2.68E−01   1   Unchanged Low       Q9UG25   B04ef6   SOCS box-containing WD prote             213.293   398   285.5392   298.9147   4.21E−01   9.00E−01   1   Unchanged Low       Q13158   C21cd4   Fas (TNFRSF6)-associated via d   263.0157   281   285.9553   276.784   1.21E−01   9.74E−02   1   Unchanged Low       Q9NW32   D10gh2   hypothetical protein FLJ10346   235.0532   386   286.3524   302.6214   2.85E−01   7.17E−01   1   Unchanged Low       O95153   M05cd5   peripheral benzodiazepine recep   155.1824   231   287.1271   224.5106   8.88E−01   5.75E−01   1   Unchanged Low       Q9BQ73   H06gh7   hypothetical protein FKSG28   212.0736   297   267.201   265.3817   4.37E−01   4.85E−01   1   Unchanged Low       Q15426   C02ef7   protein tyrosine phosphatase; re             296.9619   441   287.2583   341.7927   −4.79E−02   5.71E−01   1   Unchanged Low       Q92858   L12ab2   atonal homolog 1 ( Drosophlia )   611.3779   278   287.2641   392.3029   −1.09E+00   −1.14E+00   1   Unchanged Low       Q16849   P15ab8   protein tyrosine phosphatase; re             145.9896   55.6   287.3262   162.9842   9.77E−01   −1.39E+00   1   Unchanged Low       P11279   D07ab7   lysosomal-associated membrane   369.9925   310   287.3935   322.5735   −3.64E−01   −2.54E−01   1   Unchanged Low       Q96II1   I16gh7   hypothetical protein MGC14961   103.7251   80.7   287.4071   157.2667   1.47E+00   −3.63E−01   1   Unchanged Low       P78504   O20ab2   jagged 1 (Alagille syndrome)   255.0945   347   287.4633   296.4108   1.72E−01   4.43E−01   1   Unchanged Low       O75937   G06ef3   DnaJ (Hsp40) homolog; subfami             294.9992   264   287.503   282.0586   −3.71E−02   −1.62E−01   1   Unchanged Low       O60575   O16ef4   serine protease inhibitor; Kazal              142.2326   152   287.9   194.1988   1.02E+00   1.00E−01   1   Unchanged Low       Q9NYP7   K05gh5   homolog of yeast long chain poly   299.2029   187   288.1627   257.9759   −5.42E−02   −6.81E−01   1   Unchanged Low       O95436   H01cd6   solute carrier family 34 (sodium              238.6021   425   288.3247   317.3784   2.73E−01   8.34E−01   1   Unchanged Low       O95324   B15ab2   ATP-binding cassette; sub-family   267.704   275   288.4558   277.0901   1.08E−01   3.94E−02   1   Unchanged Low       Q9UQF6   B08ef3   ribosomal protein L36   519.2003   425   288.5855   410.9115   −8.47E−01   −2.89E−01   1   Unchanged Low       P13010   K12ef6   X-ray repair complementing defe   174.6996   256   288.9405   239.6403   7.26E−01   5.51E−01   1   Unchanged Low       Q9UJZ1   P03cd8   stomatin (EPB72)-like 2   490.6115   272   289.2003   350.5499   −7.63E−01   −8.52E−01   1   Unchanged Low       P50281   I18ab7   matrix metalloproteinase 14 (mer   126.7204   196   289.8803   204.0657   1.19E+00   6.26E−01   1   Unchanged Low       P15927   B08cd1   replication protein A2 (32 kD)   100.0172   194   290.3306   194.7022   1.54E+00   9.54E−01   1   Unchanged Low       O75496   B02ef1   germinin   466.4376   454   290.7216   403.7854   −6.82E−01   −3.84E−02   1   Unchanged Low       Q9P1E3   C23gh4   presenillns associated rhomboid-   232.5496   263   291.2445   262.3787   3.25E−01   1.79E−01   1   Unchanged Low       P40189   B14ab6   interleukin 6 signal transducer (g   330.8834   315   291.3287   312.5572   −1.84E−01   −6.89E−02   1   Unchanged Low       Q9Y259   H03ab4   choline kinase-like   328.1801   375   291.3288   331.557   −1.72E−01   1.93E−01   1   Unchanged Low       O00633   C12ef5   phosphatase and tensin homolog   199.7323   189   291.6118   226.7943   5.46E−01   −7.94E−02   1   Unchanged Low       Q13432   H13cd5   unc-119 homolog ( C. elegans )   127.1818   268   291.793   229.0999   1.20E+00   1.08E+00   1   Unchanged Low       Q9Y677   E03ef2   COP9 constitutive photomorpho             186.9367   204   291.9539   227.7917   6.43E−01   1.29E−01   1   Unchanged Low       Q9BW24   D03ef8   KIAA0676 protein   170.3265   240   292.9836   234.5628   7.83E−01   4.97E−01   1   Unchanged Low       Q9NSD9   B12cd5   phenylalanyl-tRNA synthetase b             226.6641   219   293.111   246.1288   3.71E−01   −5.22E−02   1   Unchanged Low       Q9NWQ0   C16gh3   hypothetical protein FLJ20695   497.4612   656   293.1504   482.328   −7.63E−01   4.00E−01   1   Unchanged Low       Q9NWT6   C02gh3   hypoxia-inducible factor 1; alpha   521.7793   276   293.7543   363.8746   −8.29E−01   −9.18E−01   1   Unchanged Low       Q9UPN3   J12ef7   microtubule-actin crosslinking fa             578.3578   563   294.1533   478.6344   −9.75E−01   −3.78E−02   1   Unchanged Low       Q96HW0   A06gh7   zinc finger protein 38 (KOX 25)   126.7599   355   294.3016   258.7634   1.22E+00   1.49E+00   1   Unchanged Low       Q14257   F18ab8   reticulocalbin 2; EF-hand calciu             237.969   217   295.1469   249.8842   3.11E−01   −1.36E−01   1   Unchanged Low       Q9NRJ5   J05gh4   poly(A) polymerase beta (testis s             379.2857   276   295.7341   316.91   −3.59E−01   −4.60E−01   1   Unchanged Low       P23280   P02ab3   carbonic anhydrase VI   137.6155   102   296.1358   178.6789   1.11E+00   −4.28E−01   1   Unchanged Low       Q14677   I02gh1   KIAA0171 gene product   330.738   204   296.1674   277.0019   −1.59E−01   −6.96E−01   1   Unchanged Low       Q9Y394   H17ef2   CGI-86 protein   471.0368   358   296.7589   375.1673   −6.67E−01   −3.97E−01   1   Unchanged Low       Q9UKX5   L18cd7   integrin; alpha 11   99.18133   126   297.0397   173.978   1.58E+00   3.42E−01   1   Unchanged Low       Q92539   G02gh1   lipin 2   260.7493   235   297.1151   264.3623   1.88E−01   −1.49E−01   1   Unchanged Low       Q9NW01   G10gh3   hypothetical protein FLJ10402   165.6121   135   297.1276   199.1936   8.43E−01   −2.97E−01   1   Unchanged Low       Q9NUW5   N21gh3   hypothetical protein FLJ11099   228.3252   247   297.5163   257.4882   3.82E−01   1.11E−01   1   Unchanged Low       Q9BYC4   C13gh8   mitochondrial ribosomal protein              478.9122   408   297.754   394.9285   −6.86E−01   −2.31E−01   1   Unchanged Low       P02545   F01ab7   lamin A/C   707.7874   294   297.9921   433.306   −1.25E+00   −1.27E+00   1   Unchanged Low       O60585   A17cd6   serine/arginine repetitive matrix              318.399   331   298.2057   315.9302   −9.45E−02   5.68E−02   1   Unchanged Low       P23458   L12ef5   Janus kinase 1 (a protein tyrosin   385.7348   441   298.2124   375.1408   −3.71E−01   1.95E−01   1   Unchanged Low       Q9BY13   O06gh8   hook3 protein   435.0319   471   298.2969   401.4116   −5.44E−01   1.14E−01   1   Unchanged Low       Q9UBC2   C05gh5   epidermal growth factor receptor   171.9695   271   298.6179   247.3586   7.96E−01   6.59E−01   1   Unchanged Low       O76022   A14cd7   E1B-55 kDa-associated protein 5   256.9682   243   298.7615   266.0871   2.17E−01   −8.34E−02   1   Unchanged Low       P33993   K04ef6   MCM7 minichromosoma mainten   239.0601   165   298.875   234.4011   3.22E−01   −5.33E−01   1   Unchanged Low       Q92963   F02cd2   Ric-like: expressed in many tissu   447.2008   499   299.9377   415.4004   −5.76E−01   1.58E−01   1   Unchanged Low       Q9HAF1   P09gh5   hypothetical protein FLJ11730   270.4702   414   300.0397   328.0993   1.50E−01   8.13E−01   1   Unchanged Low       Q9NZ36   P02gh4   uncharacterized hypothalamus p   505.7323   333   300.1219   379.485   −7.53E−01   −6.05E−01   1   Unchanged Low       Q9BQQ3   C09gh8   golgi phosphoprotein 5   208.3671   343   300.1696   283.9342   5.27E−01   7.20E−01   1   Unchanged Low       O95214   P09ef3   leptin receptor overlapping trans             292.4076   419   300.357   337.2896   3.87E−02   5.19E−01   1   Unchanged Low       Q9Y294   A21ef8   DKFZP547E2110 protein   168.5906   243   301.1573   237.0749   8.54E−01   5.47E−01   1   Unchanged Low       O95810   O01cd4   serum deprivation response (phc   279.903   272   301.2133   284.3868   1.06E−01   −4.11E−02   1   Unchanged Low       P30670   L21ab4   guanine nucleotide binding prote   470.8713   466   301.8899   412.8188   −6.41E−01   −1.59E−02   1   Unchanged Low       P51946   O14ef5   cyclin H   180.4218   244   301.9337   242.2819   7.43E−01   4.38E−01   1   Unchanged Low       Q15290   G18cd1   retinoblastoma binding protein 6   298.4739   346   302.0906   315.4543   1.74E−02   2.12E−01   1   Unchanged Low       Q9NX11   A03gh3   hypothetical protein FLJ20498   165.3845   190   302.1175   219.2418   8.69E−01   2.02E−01   1   Unchanged Low       Q9P0S3   A23ef2   hypothetical protein LOC51240   187.2653   229   302.318   239.5316   6.91E−01   2.90E−01   1   Unchanged Low       P04554   H11ab8   protamine 2   393.1528   362   302.3989   352.4183   −3.79E−01   −1.20E−01   1   Unchanged Low       O15243   O05ef4   leptin receptor gene-related prot             329.3033   391   302.5417   340.9139   −1.22E−01   2.47E−01   1   Unchanged Low       O43717   G03cd7   tumor differentially expressed 1   284.4846   364   302.9444   317.004   9.07E−02   3.54E−01   1   Unchanged Low       O95876   J10ef1   hypothetical protein LOC51057   172.7128   226   302.9853   233.8891   8.11E−01   3.88E−01   1   Unchanged Low       Q9H8D5   N17gh5   tumor endothelial marker 6   247.105   190   303.4837   246.7925   2.96E−01   −3.81E−01   1   Unchanged Low       Q9Y3B6   D24ef1   CGI-112 protein   493.6755   288   303.7855   361.6747   −7.01E−01   −7.80E−01   1   Unchanged Low       Q9P0S7   E13ef2   hypothetical protein LOC51238   143.0704   139   303.896   195.3392   1.09E+00   −4.11E−02   1   Unchanged Low       O60630   D22ab4   deltex homolog 1( Drosophilia )   310.6617   221   303.9702   278.4627   −3.14E−02   −4.93E−01   1   Unchanged Low       O95285   O07gh1   macrophage erythroblast attache   332.2343   413   304.0714   349.7511   −1.28E−01   3.14E−01   1   Unchanged Low       Q08945   G17cd2   structure specific recognition pro             335.05   229   304.6617   289.639   −1.37E−01   −5.48E−01   1   Unchanged Low       O43583   D08cd3   density-regulated protein   203.0088   253   304.7034   253.5145   5.86E−01   3.17E−01   1   Unchanged Low       O95149   D04cd5   RNA; U transporter 1   186.979   254   304.889   248.5641   7.05E−01   4.41E−01   1   Unchanged Low       Q9HAS8   N10gh4   elaC homolog 2 ( E. coli )   243.3076   331   304.8937   293.0254   3.26E−01   4.44E−01   1   Unchanged Low       Q9BQ39   A23gh6   nucleolar protein GU2   234.3353   160   305.2734   233.2592   3.82E−01   −5.49E−01   1   Unchanged Low       O15304   C06ef6   CD27-binding (Slva) protein   88.75727   153   305.4708   182.3257   1.78E+00   7.83E−01   1   Unchanged Low       Q15394   I08gh1   basic leucine-zipper protein BZA   347.7168   384   305.6252   345.6465   −1.66−01   1.42E−01   1   Unchanged Low       Q9NZA3   N09ef1   CDA14   235.1955   312   305.7623   284.2776   3.79E−01   4.07E−01   1   Unchanged Low       P26022   P23ab8   pentaxin-related gene; rapidly ln             97.61703   61.3   305.8598   154.9189   1.65E+00   −6.72E−01   1   Unchanged Low       Q00536   L24ef5   PCTAIRE protein kinase 1   290.1914   359   306.0473   318.5577   7.68E−02   3.09E−01   1   Unchanged Low       Q9UMW5   E19ef2   cerebral cell adhesion molecule   52.28353   234   306.6326   197.6582   2.55E+00   2.16E+00   1   Unchanged Low       O95353   J17cd6   Cdc42 effector protein 3   95.65314   208   306.7186   203.4709   1.68E+00   1.12E+00   1   Unchanged Low       O95808   B03ef2   arsenate resistance protein ARS             187.799   225   307.4311   240.0311   7.11E−01   2.60E−01   1   Unchanged Low       Q9BXJ8   O17gh8   transmembrane protein induced I   411.8484   646   308.2116   455.5065   −4.18E−01   6.50E−01   1   Unchanged Low       P36776   A06cd5   protease; serine; 15   390.4608   365   308.5755   354.6324   −3.40E−01   −9.78E−02   1   Unchanged Low       Q9BUR9   M19gh6   hypothetical protein MGC4614   250.3191   338   308.7431   299.1204   3.03E−01   4.35E−01   1   Unchanged Low       Q9Y3R1   F23cd6   Rab acceptor 1 (prenylated)   158.9446   207   308.7948   224.7776   9.58E−01   3.78E−01   1   Unchanged Low       Q92997   Do3ef7   dishevelled; dsh homolog 3 (Dro             240.0941   305   309.2314   284.6254   3.65E−01   3.43E−01   1   Unchanged Low       O14682   N17cd3   ectodermal-neural cortex (with B             326.0664   189   309.539   274.7193   −7.50E−02   −7.90E−01   1   Unchanged Low       Q9Y255   I08cd8   px19-like protein   533.9688   455   309.7497   432.9739   −7.86E−01   −2.30E−01   1   Unchanged Low       Q16664   O17ef4   protein \A\**   354.4762   286   310.2736   316.9703   −1.92E−01   −3.09E−01   1   Unchanged Low       P31943   O04ab7   heterogeneous nuclear ribonucle   690.0051   250   310.5901   416.9005   −1.15E+00   −1.46E+00   1   Unchanged Low       P49848   J09cd2   TAF6 RNA polymerase II; TATA   151.1422   133   310.9274   198.2917   1.04E+00   −1.87E−01   1   Unchanged Low       Q04984   P19ab8   heat shock 10 kD protein 1 (chap             338.1568   327   311.1011   325.4422   −1.20E−01   −4.81E−02   1   Unchanged Low       P20719   N08ef4   homeo box A5   271.4135   326   311.2742   302.8287   1.98E−01   2.63E−01   1   Unchanged Low       Q9H5Y0   D21gh7   hypothetical protein FLJ22795   325.1674   305   311.3753   313.8457   −6.25E−02   −9.24E−02   1   Unchanged Low       P19021   G15ab8   peptidylglycine alpha-amidating              219.5791   273   311.913   268.0943   5.06E−01   3.13E−01   1   Unchanged Low       Q92544   B13gh1   KIAA0255 gene product   270.8313   307   312.0297   296.5662   2.04E−01   1.80E−01   1   Unchanged Low       Q12907   G07cd7   chromosome 5 open reading frar             313.0938   222   312.5092   282.474   −2.70E−03   −4.97E−01   1   Unchanged Low       Q9BW91   C03gh6   nudix (nucleoside diphosphate lli             346.395   314   312.5575   324.483   −1.48E−01   −1.39E−01   1   Unchanged Low       P53365   M23cd8   partner of RAC1 (arfaptin 2)   293.2566   349   312.9335   318.382   9.37E−02   2.51E−01   1   Unchanged Low       P35869   O17ab2   aryl hydrocarbon receptor   249.5731   417   313.1153   326.5306   3.27E−01   7.40E−01   1   Unchanged Low       Q13145   I19cd8   putative transmembrane protein   490.8698   608   313.616   470.7589   −6.46E−01   3.08E−01   1   Unchanged Low       O14747   A18e86   death-associated protein 6   348.2382   450   313.7398   370.593   −1.51E−01   3.69E−01   1   Unchanged Low       Q9GZT5   H03gh7   wingless-type MMTV integration   362.0025   327   313.9764   334.369   −2.05E−01   −1.46E−01   1   Unchanged Low       P08174   M19ef1   decay accelerating factor for corr             705.5781   457   314.0939   492.3204   −1.17E+00   −6.26E−01   1   Unchanged Low       Q9H689   K01gh4   hypothetical protein RG083M05              241.9641   291   314.1855   282.3328   3.77E−01   2.65E−01   1   Unchanged Low       Q9P0T7   K05ef2   hypothetical protein LOC51235   266.1575   324   314.3982   301.4061   2.40E−01   2.82E−01   1   Unchanged Low       Q9H2V7   I12gh8   spinster-like protein   275.9977   394   314.4425   328.1261   1.88E−01   5.13E−01   1   Unchanged Low       Q9NWT0   D23gh2   hypothetical protein FLJ20625   420.628   488   314.6523   407.636   −4.19E−01   2.13E−01   1   Unchanged Low       Q9Y6X2   E22cd6   protein inhibitor of activated STA   149.0425   237   315.009   233.7882   1.08E+00   6.71E−01   1   Unchanged Low       Q9P1P1   F10ef8   clone FLB1727 (LOC51215)   419.9659   330   315.0092   355.1102   −4.15E−01   −3.46E−01   1   Unchanged Low       P23919   H04cd7   deoxythymidylate kinase (thymid             123.4582   84.1   315.562   174.3854   1.35E+00   −5.53E−01   1   Unchanged Low       P37140   D09ab8   protein phosphatase 1; catalytic              355.0781   503   315.7751   391.3748   −1.69E−01   5.03E−01   1   Unchanged Low       Q9NW54   B22gh2   homolog of rat nadrin   432.3799   670   315.8314   472.8474   −4.53E−01   6.33E−01   1   Unchanged Low       Q9UMS0   C05ef4   HIRA interacting protein 5   504.0153   382   315.8386   400.6081   −6.74E−01   −4.00E−01   1   Unchanged Low       P14207   E23ef1   folate receptor 2 (fetal)   235.5291   154   316.0649   235.1893   4.24E−01   −6.13E−01   1   Unchanged Low       Q9UHC7   L05ef4   makorin; ring finger protein; 1   243.752   243   316.3297   267.5313   3.76E−01   −7.36E−03   1   Unchanged Low       O75844   K23cd6   zinc metalloproteinase (STE24 h   338.221   174   316.3789   276.2357   −9.63E−02   −9.58E−01   1   Unchanged Low           P18gh8   LIM homeobox protein 4   87.11814   84.8   316.6454   162.8523   1.86E+00   −3.90E−02   1   Unchanged Low       P16587   P19ab2   ADP-ribosylation factor 3   444.3724   348   317.1873   369.9292   −4.86E−01   −3.52E−01   1   Unchanged Low       Q9NVY2   F18gh2   hypothetical protein FLJ10439   420.4716   399   317.2936   378.7795   −4.06E−01   −7.72E−02   1   Unchanged Low       Q9Y3I1   J09ef4   F-box only protein 7   368.7457   422   317.6515   369.3121   −2.15E−01   1.93E−01   1   Unchanged Low       Q9H320   P21cd8   variable charge; X chromosome   147.0814   348   318.4769   271.2531   1.11E+00   1.24E+00   1   Unchanged Low       P49903   J11ef4   selenium donor protein   329.031   446   318.9322   364.5082   −4.50E−02   4.37E−01   1   Unchanged Low       O00506   B05cd6   serine/threonine kinase 25 (STE             273.696   275   319.3179   289.4017   2.22E−01   7.86E−03   1   Unchanged Low       O00273   F14ab5   DNA fragmentation factor; 45 kD   328.993   401   319.634   350.0198   −4.16E−02   2.87E−01   1   Unchanged Low       Q08170   H11cd2   splicing factor; arginine/seriene-ri             231.1994   193   319.7733   247.9554   4.68E−01   −2.61E−01   1   Unchanged Low       Q9Y3B8   N15ef8   small fragment nuclease   120.8094   282   320.0578   240.8904   1.41E+00   1.22E+00   1   Unchanged Low       Q9P0N0   E11ef2   mitochondrial ribosomal protein              377.6692   391   320.1382   362.9626   −2.38E−01   5.03E−02   1   Unchanged Low       Q9BRI3   D11gh8   hypothetical protein MGC11303              373.5695   391   320.4318   361.6895   −2.21E+00   8.60E−02   1   Unchanged Low       Q9Y319   D19ef2   CGI-30 protein   107.1253   123   320.4576   183.4471   1.58E+00   1.97E−01   1   Unchanged Low       Q16514   M17gh1   TAF12 RNA polymerase II; TAT             116.3618   304   320.8611   246.9777   1.46E+00   1.38E+00   1   Unchanged Low       P13489   D13ef7   ribonuclease/angiogenin inhibito             224.1663   232   321.0895   259.1076   5.18E−01   5.00E−02   1   Unchanged Low       Q99987   P08ef5   vaccinia related kinase 2   205.9202   194   321.2364   240.3908   6.42E−01   −8.59E−02   1   Unchanged Low       P56181   H21ef1   NADH dehydrogenase (ubiquino             435.0715   319   321.3696   358.4382   −4.37E−01   −4.48E−01   1   Unchanged Low       P51148   N18ab8   RAB5C; member RAS oncogene   329.7976   358   321.5906   336.6203   −3.64E−02   1.20E−01   1   Unchanged Low       Q9HD34   E12gh4   CGI-203 protein   257.866   249   322.345   276.3612   3.22E−01   −5.12E−02   1   Unchanged Low       Q9HAN2   F02gh6   purnilio homolog 2 ( Drosophila )   291.9641   326   322.4096   313.4126   1.43E−01   1.58E−01   1   Unchanged Low       P08107   K13ef5   heat shock 70 kD protein 1A   535.4871   382   322.6223   413.3803   −7.31E−01   −4.87E−01   1   Unchanged Low       O60499   N18cd3   syntaxin 10   189.7411   304   322.7738   272.2579   7.66E−01   6.81E−01   1   Unchanged Low       Q9HBL3   M19gh4   N-terminal kinase-like   165.2938   224   323.2472   237.4707   9.68E−01   4.38E−01   1   Unchanged Low       Q9BSJB   D22gh6   KIAA0747 protein   549.1645   575   323.5208   482.4222   −7.63E−01   8.53E−02   1   Unchanged Low       O60838   G09gh7   SAC2 suppressor of actin multati             216.0571   254   324.4643   264.8237   5.87E−01   2.33E−01   1   Unchanged Low       Q98TM6   M11gh8   hypothetical protein MGC3195   371.9412   334   324.5103   343.6429   −1.97E−01   −1.53E−01   1   Unchanged Low       Q9H4L0   K06gh5   leucine zipper protein FKSG14   47.34403   70.6   324.6661   147.5387   2.78E+00   5.77E−01   1   Unchanged Low       P50402   I14ab3   emerin (Emery-Dreifuss muscula   321.3743   304   324.6751   316.6654   1.47E−02   −8.04E−02   1   Unchanged Low       Q9NZP7   G05ef3   calcium binding protein Cab45 p             336.1107   239   324.6956   299.844   −4.98E−02   −4.94E−01   1   Unchanged Low       P49116   G22cd2   nuclear receptor subfamily 2; gro             295.9342   224   325.1253   281.6482   1.36E−01   −4.03E−01   1   Unchanged Low       P11234   D14ab8   v-ral simian leukemia viral oncog             565.699   444   325.5924   444.9874   −7.97E−01   −3.51E−01   1   Unchanged Low       P15408   D21ab5   FOS-like antigen 2   265.6989   437   325.8448   342.8236   2.94E−01   7.18E−01   1   Unchanged Low       Q9P1Q8   N05cd8   RAB3A interacting protein (rabin             357.6493   253   326.2784   312.2142   −1.33E−01   −5.03E−01   1   Unchanged Low       P39060   P16ef6   collagen; type XVIII; alpha 1   151.6584   212   326.8288   230.0488   1.11E+00   4.81E−01   1   Unchanged Low       Q9Y2N3   N05gh1   KIAA0618 gene product   378.8717   252   326.8347   319.0933   −2.13E−01   −5.91E−01   1   Unchanged Low       P02749   M22ab2   apolipoprotein H (beta-2-glycopn             408.7454   226   327.1228   320.758   −3.21E−01   −8.52E−01   1   Unchanged Low       Q9P189   L20gh3   hypothetical protein PRO1855   392.3328   358   327.1908   359.0226   −2.62E−01   −1.34E−01   1   Unchanged Low       O43822   B19ab4   chromosome 21 open reading fr             249.9987   297   327.8679   291.7148   3.91E−01   2.50E−01   1   Unchanged Low       Q9UNZ2   N15ef2   likely ortholog of rat p47   413.5167   519   327.9429   420.0854   −3.35E−01   3.27E−01   1   Unchanged Low       Q9Y4G5   B22cd8   dynein; cytoplasmic; heavy poly             376.6624   426   327.9518   376.7971   −2.00E−01   1.77E−01   1   Unchanged Low       Q13310   C13cd4   poly(A) binding protein; cytoplas             316.8746   338   328.1257   327.507   5.03E−02   9.11E−02   1   Unchanged Low       P45974   O14cd3   ubiquitin specific protease 5 (Iso             268.1073   316   328.1257   304.4284   2.95E−01   2.39E−01   1   Unchanged Low       P55317   A04ab7   hepatocyte nuclear factor 3; alph   273.7527   306   328.8562   302.8162   2.65E−01   1.60E−01   1   Unchanged Low       O43364   H08cd8   homeo box A2   511.053   468   329.1292   435.9554   −6.35E−01   −1.28E−01   1   Unchanged Low       P55345   H15ab6   HMT1 hnRNP methyltransferase   384.8758   307   329.5023   333.8774   −1.47E−01   −2.48E−01   1   Unchanged Low       P48230   O22cd2   transmembrane 4 superfamily m             565.1635   417   330.825   437.5376   −7.73E−01   −4.40E−01   1   Unchanged Low       Q9BUY3   C21gh5   sorting nexin 6   166.5144   297   330.8949   264.7192   9.91E−01   8.34E−01   1   Unchanged Low       O00115   B01ef6   deoxyribonuclease II; lysosomal   275.2503   372   331.0554   326.0947   2.66E−01   4.34E−01   1   Unchanged Low       O43318   M11cd2   mitogen-activated protein kinase   186.7739   247   331.1308   254.8269   8.26E−01   4.01E−01   1   Unchanged Low       O95572   B08gh1   mitofusin 2   252.7846   277   331.4516   287.175   3.91E−01   1.33E−01   1   Unchanged Low       P35080   K12ab8   profilin 2   111.4363   85.9   332.2299   176.518   1.58E+00   −3.76E−01   1   Unchanged Low       Q9NW29   E24gh3   hypothetical protein FLJ10350   219.5611   173   332.8499   241.9521   6.00E−01   −3.40E−01   1   Unchanged Low       Q9NZE9   O07ef2   BRAF35/HDAC2 complex (80 kD   219.3916   348   332.8813   299.9861   6.01E−01   6.64E−01   1   Unchanged Low       Q9BYV2 C   E05gh8   ring finger protein 30   500.2246   338   333.9675   390.6398   −5.83E−01   −5.66E−01   1   Unchanged Low       Q9UJX4   F02ef2   anaphase promoting complex sul             237.1218   269   334.5884   280.1684   4.97E−01   1.81E−01   1   Unchanged Low       O00302   B19cd6   calcium homeostasis endoplasm             327.1489   382   334.7371   347.7981   3.31E−02   2.22E−01   1   Unchanged Low       Q92886   K23cd1   neurogenin 1   290.2357   283   335.1054   302.7027   2.07E−01   −3.76E−02   1   Unchanged Low       O14929   P07cd3   histone acetyltransferase 1   344.9153   130   335.4301   270.1111   −4.02E−02   −1.41E+00   1   Unchanged Low       Q9NVK7   M18gh3   chromosome 19 open reading fre   281.2043   287   335.4383   301.1995   2.54E−01   2.92E−02   1   Unchanged Low       Q9UBN0   P09ef4   proline rich 3   309.9093   344   335.4526   329.7234   1.14E−01   1.50E−01   1   Unchanged Low       O43611   E14cd3   cytoplasmic linker 2   180.9108   220   336.1459   245.5832   8.94E−01   2.80E−01   1   Unchanged Low       O94777   G23cd4   doiichyl-phosphate mannosyltran   294.1356   244   336.7183   291.5641   1.95E−01   −2.71E−01   1   Unchanged Low       Q14669   K05gh1   thyroid hormone receptor interac   486.9829   397   337.0199   406.8782   −5.31E−01   −2.96E−01   1   Unchanged Low       Q9NUR0   B20gh3   hypothetical protein FLJ11196   63.09205   107   337.0769   168.9127   2.42E+00   7.56E−01   1   Unchanged Low       Q16822   L08ab8   phosphoenolpyruvate carboxykin   262.4601   156   337.1655   251.8272   3.61E−01   −7.52E−01   1   Unchanged Low       Q9Y640   A14cd8   stromal cell derived factor recept   215.2348   220   337.2906   257.3848   6.48E−01   2.92E−02   1   Unchanged Low       P48595   C01cd1   serine (or cysteine) proteinase in   62.04001   410   337.3872   269.7194   2.44E+00   2.72E+00   1   Unchanged Low       P26639   M15cd2   threonyl-tRNA synthetase   355.1309   422   337.8401   371.5003   −7.20E−02   2.47E−01   1   Unchanged Low       P29597   O03cd3   tyrosine kinase 2   209.3427   258   338.1471   268.5377   6.92E−01   3.02E−01   1   Unchanged Low       O60671   B02ab8   RAD1 homolog ( S. pombe )   188.2718   104   339.1461   210.3983   8.49E−01   −8.59E−01   1   Unchanged Low       Q9NW97   P17gh2   hypothetical protein FLJ10199   262.3124   536   339.3086   379.0815   3.71E−01   1.03E+00   1   Unchanged Low       Q9P027   O23ef8   HSPC133 protein   616.0461   363   339.3102   439.5495   −8.60E−01   −7.62E−01   1   Unchanged Low       O95772   E20gh8   hypothetical protein MGC3251   195.9084   227   339.3844   254.0574   7.93E−01   2.12E−01   1   Unchanged Low       Q9NR28   N13gh4   second mitochondria-derived act   271.4457   543   339.8107   384.7351   3.24E−01   1.00E+00   1   Unchanged Low       P11413   F15ab3   glucose-6-phosphate dehydroge             258.0938   135   340.0217   244.4906   3.98E−01   −9.31E−01   1   Unchanged Low       Q99567   A04ab8   nucleoporin 88 kD   464.4826   320   340.5878   375.0149   −4.48E−01   −5.38E−01   1   Unchanged Low       Q96ZR9   F22gh7   ring finger protein 27   206.7918   398   340.7239   315.1764   7.20E−01   9.45E−01   1   Unchanged Low       O43632   L22cd6   gamma-tubulin complex protein 2   328.0052   322   341.4805   330.4468   5.81E−02   −2.73E−02   1   Unchanged Low       Q9Y305   I05cd8   Mitochondrial Acyl-CoA Thioeste   447.9229   475   341.5085   421.5064   −3.91E−01   8.49E−02   1   Unchanged Low       P17096   L14ef6   high-mobility group (nonhistone              393.4158   266   341.5301   333.78   −2.04E−01   −5.62E−01   1   Unchanged Low       P28677   E10cd3   visinin-like 1   235.283   241   341.6123   272.797   5.38E−01   3.76E−02   1   Unchanged Low       Q9UBX5   K04cd6   fibulin 5   79.52593   108   341.7638   176.4964   2.10E+00   4.44E−01   1   Unchanged Low       Q9Y304   E12ef2   ovarian cancer overexpressed 1   326.0044   238   341.8947   301.8585   6.87E−02   −4.56E−01   1   Unchanged Low       O15379   L16ef6   histone deacetylase 3   198.0005   380   342.3529   306.8418   7.90E−01   9.41E−01   1   Unchanged Low       Q02790   H16ab5   FK506 binding protein 4 (59 kD)   323.5993   240   343.4254   302.2597   8.58E−02   −4.33E−01   1   Unchanged Low       Q9H240   K12ef5   Notch homolog 2 ( Drosophila )   270.5904   566   343.4339   393.3189   3.44E−01   1.06E+00   1   Unchanged Lo       O76095   P22cd8   Jumping translocation breakpoint   252.8696   227   343.482   274.4316   4.42E−01   −1.56E−01   1   Unchanged Low       Q9Y5Q8   P07cd7   general transcription factor IIIC;              545.6403   324   343.9958   404.6602   −6.66E−01   −7.50E−01   1   Unchanged Low       Q9NNW5   H06ef8   WD repeat domain 6   254.1607   369   344.0253   322.3381   4.37E−01   5.37E−01   1   Unchanged Low       P01121   C09ef6   ras homolog gene family; memb             241.7544   304   344.0732   296.4811   5.09E−01   3.29E−01   1   Unchanged Low       Q9H0V7   K18gh8   hypothetical protein DKFZp564O   568.248   304   344.2985   405.6684   −7.23E−01   −9.00E−01   1   Unchanged Low       O60664   P02cd5   cargo selection protein (mannos             520.0919   232   344.5523   365.5782   −5.94E−01   −1.16E+00   1   Unchanged Low       P56554   O15cd3   ubiquitin-conjugating enzyme E2   374.4383   417   345.0269   378.959   −1.18E−01   1.57E−01   1   Unchanged Low       O00330   O06cd3   Pyruvate dehydrogenase comple   345.9372   430   345.2213   373.6892   −2.99E−03   3.14E−01   1   Unchanged Low       O60784   N17cd5   target of myb1 (chicken)   364.3098   317   345.2431   342.086   −7.76E−02   −2.02E−01   1   Unchanged Low       Q9NQZ0   H03ef4   CMP-N-acetylneuraminic acid sy   788.5176   339   345.3498   491.0715   −1.19E+00   −1.22E+00   1   Unchanged Low       P52790   A04ab5   hexokinase 3 (white cell)   260.6034   430   345.4621   345.2169   4.07E−01   7.21E−01   1   Unchanged Low       P52815   B10cd1   mitochondrial ribosomal protein              234.3191   277   345.7776   285.7775   5.61E−01   2.43E−01   1   Unchanged Low       O14983   O10ef1   ATPase; Ca++ transporting; card   167.4066   223   346.1734   245.4613   1.05E+00   4.12E−01   1   Unchanged Low       P04259   D01ab7   keratin 6B   534.1837   405   347.6543   428.9832   −6.20E−01   −3.99E−01   1   Unchanged Low       P16455   M04ef6   O-6-methylguanine-DNA methylt             299.0887   307   348.0545   318.0812   2.19E−01   3.81E−02   1   Unchanged Low       Q9Y5L9   N04cd6   Snf2-related CBP activator prote             285.2875   187   348.0925   273.2945   2.87E−01   −6.13E−01   1   Unchanged Low       P41214   A16gh1   ligatin   237.0742   307   348.5538   297.4677   5.56E−01   3.72E−01   1   Unchanged Low       Q9H6U4   P13gh5   hypothetical protein FLJ21865   419.2747   175   348.8375   314.4039   −2.65E−01   −1.26E+00   1   Unchanged Low       Q15393   L10ef7   splicing factor 3b; subunit 3; 130             242.1115   239   349.6571   277.0735   5.30E−01   −1.59E−02   1   Unchanged Low       P55055   C04gh1   nuclear receptor subfamily 1; gro   325.6291   368   349.8393.   347.7942   1.03E−01   1.76E−01   1   Unchanged Low       P51805   M03ef4   SEX gene   303.0664   383   350.6414   345.4093   2.10E−01   3.36E−01   1   Unchanged Low       O75815   G23ab3   breast cancer anti-estrogen resis   249.1903   293   350.9571   297.768   4.94E−01   2.34E−01   1   Unchanged Low       Q9Y2Y9   F19ef2   Kruppel-like factor 13   241.1753   366   351.0501   319.2905   5.42E−01   6.00E−01   1   Unchanged Low       Q99633   D04cd3   pre-mRNA processing factor 1B   405.046   348   351.3478   366.1886   −2.05E−01   −2.18E−01   1   Unchanged Low       P05155   C08ab3   serine (or cysteine) proteinase in   303.3386   334   351.5074   329.7432   2.13E−01   1.41E−01   1   Unchanged Low       Q9UN50   O16cd7   EAP30 subunit of ELL complex   321.9045   326   351.5535   333.1657   1.27E−01   1.84E−02   1   Unchanged Low       Q14011   E11ab4   cold inducible RNA binding prote   292.5107   412   351.6685   352.0144   2.66E−01   4.94E−01   1   Unchanged Low       O75807   M02ef3   protein phosphatase 1; regulator   371.7509   652   352.5048   458.6852   −7.67E−02   8.10E−01   1   Unchanged Low       Q14457   K19ab3   beciin 1 (coiled-coil); myosin-like   368.4142   678   352.9542   466.4393   −6.18E−02   8.80E−01   1   Unchanged Low       Q02818   J06ef6   nucleobindin 1   330.8747   213   353.1168   298.8382   9.39E−02   −6.39E−01   1   Unchanged Low       O15235   L10gh1   mitochondrial ribosomal protein              355.1234   467   353.2438   391.6738   −7.66E−03   3.94E−01   1   Unchanged Low       Q9Y3E0   A02ef2   CGI-141 protein   152.8668   320   353.6986   275.4907   1.21E+00   1.07E+00   1   Unchanged Low       Q9NQZ5   H19gh4   START domain containing 7   277.2941   280   353.7264   303.5369   3.51E−01   1.19E−02   1   Unchanged Low       Q9UHW4   D24ef8   protein x 0001   266.9848   291   353.7644   303.9535   4.06E−01   1.25E−01   1   Unchanged Low       P82914   P04gh7   mitochondrial ribosomal protein              444.1517   417   354.4965   405.0567   −3.25E−01   −9.27E−02   1   Unchanged Low       P25787   L11ef7   proteasome (prosome; macropal             432.9379   526   355.1116   437.9448   −2.86E−01   2.80E−01   1   Unchanged Low       P26447   D02cd1   S100 calcium binding protein A4   198.7401   273   355.1396   275.5734   8.38E−01   4.57E−01   1   Unchanged Low       Q9Y605   P02gh8   T-cell activation protein   411.1148   356   355.1531   373.9359   −2.11E−01   −2.10E−01   1   Unchanged Low       Q14776   K14cd4   leucine-zipper-like transcriptiona   202.0365   273   355.4522   276.788   8.15E−01   4.34E−01   1   Unchanged Low       P30837   C02ab2   aldehyde dehydrogenase 1 famil   631.0407   451   355.7998   479.1158   −8.27E−01   −4.86E−01   1   Unchanged Low       P09668   L03ef7   cathepsin H   460.8488   564   356.7735   460.5856   −3.69E−01   2.92E−01   1   Unchanged Low       Q02313   J02gh8   Krueppel-related zinc finger prot             402.289   391   356.9162   383.4797   −1.73E−01   −4.02E−02   1   Unchanged Low       Q13148   H11cd7   TAR DNA binding protein   322.5816   353   357.1404   344.328   1.47E−01   1.31E−01   1   Unchanged Low       Q16645   K24ab5   FK506 binding protein 1B (12.6              216.7704   488   357.2698   353.4204   7.21E−01   1.17E+00   1   Unchanged Low           N02gh8   protein phosphatase 1; regulator   77.52993   71.1   357.2714   168.643   2.20E+00   −1.24E−01   1   Unchanged Low       P57739   F18gh1   claudin 2   188.162   238   357.443   261.2968   9.26E−01   3.41E−01   1   Unchanged Low       O60568   F13cd4   procollagen-lysine; 2-oxoglutarat   332.5306   269   357.5594   319.8117   1.05E−01   −3.04E−01   1   Unchanged Low       Q9HAU4   N11gh5   E3 ublquitin ligase SMURF2   425.5948   665   357.6911   482.7167   −2.51E−01   6.44E−01   1   Unchanged Low       P49914   J01cd6   5; 10-methenyltetrahydrofolate sy   340.2344   238   358.0826   312.027   7.38E−02   −5.17E−01   1   Unchanged Low       O60510   E11cd8   atrophin-1 interacting protein 1;              171.9425   265   358.342   265.2168   1.06E+00   6.26E−01   1   Unchanged Low       Q98X68   L15gh8   histidine triad nucleotide binding   207.0703   360   358.5328   308.6409   7.92E−01   7.99E−01   1   Unchanged Low       P29084   B02ab5   general transcription factor IIE; p   261.3572   225   358.621   281.687   4.57E−01   −2.17E−01   1   Unchanged Low       P09526   C05ef6   RAP1B; member of RAS oncoge             320.4156   355   359.0861   344.9493   1.64E−01   1.49E−01   1   Unchanged Low       O15471   P01ef4   leukocyte immunogiobuiln-like re   219.8277   260   359.2909   279.8225   7.09E−01   2.44E−01   1   Unchanged Low       Q9UEE9   K03ab3   craniofacial development protein   124.0304   245   359.5047   242.684   1.54E+00   9.79E−01   1   Unchanged Low       Q15011   L03ef3   homocysteine-inducible; endopia   352.4459   183   359.7095   298.5074   2.94E−02   −9.43E−01   1   Unchanged Low       Q9BWG8   A13gh6   hypothetical protein MGC2491   170.1162   203   360.534   244.6389   1.08E+00   2.57E−01   1   Unchanged Low       Q9Y397   A04ef2   zinc finger; DHHC domain contai   431.1743   495   360.6182   428.8727   −2.58E−01   1.99E−01   1   Unchanged Low       Q14596   H17ab7   membrane component; chromos             303.2476   402   361.5265   355.7499   2.54E−01   4.08E−01   1   Unchanged Low       P23497   C13cd2   nuclear antigen Sp100   331.8296   491   361.9825   394.8464   1.25E−01   5.64E−01   1   Unchanged Low       Q16633   A24cd1   POU domain; class 2; associatin             103.1231   99.3   382.0007   188.1549   1.81E+00   −5.39E−02   1   Unchanged Low       Q99961   J12cd1   SH3-domain GRB2-like 1   231.086   247   362.8536   280.235   6.51E−01   9.47E−02   1   Unchanged Low       Q07021   N20ab3   complement component 1; q sub             471.8742   202   363.3385   345.9018   −3.77E−01   −1.22E+00   1   Unchanged Low       Q16513   E04cd1   protein kinase C-like 2   546.0111   561   364.4852   490.5792   −5.83E−01   3.97E−02   1   Unchanged Low       Q9H070   H10cd8   adaptor-related protein complex:   353.2901   278   364.7541   331.9695   4.61E−02   −3.46E−01   1   Unchanged Low       Q13227   A16ab5   G protein pathway suppressor 2   557.5311   352   364.8449   424.6909   −6.12E−01   −6.65E−01   1   Unchanged Low       P20339   M03ef5   RAB5A; member RAS oncogene   404.6579   664   365.7139   478.1731   −1.46E−01   7.15E−01   1   Unchanged Low       Q9NXX4   G15gh2   hypothetical protein FLJ20005   155.2731   248   365.9622   255.5867   1.24E+00   6.61E−01   1   Unchanged Low       Q92900   N17cd1   regulator of nonsense transcripts   328.2926   316   366.2931   336.7297   1.58E−01   −5.69E−02   1   Unchanged Low       Q9H2K4   I05gh3   chromosome 11 open reading fra   198.6548   155   366.4866   240.051   8.83E−01   −3.58E−01   1   Unchanged Low       O14917   E17ef4   protocadherin 17   250.3859   311   366.6879   309.398   5.50E−01   3.13E−01   1   Unchanged Low       Q9NZ88   J06gh3   chromosome 6 open reading frar   199.6701   362   367.2681   309.7781   8.79E−01   8.60E−01   1   Unchanged Low       Q9BYC8   C15gh8   mitochondrial ribosomal protein 1   257.9414   429   367.9727   351.4981   5.13E−01   7.33E−01   1   Unchanged Low       Q15311   C21cd7   ralA binding protein 1   295.4648   411   368.6028   358.3107   3.19E−01   4.76E−01   1   Unchanged Low       Q9NWE9   E02gh3   hypothetical protein FLJ10074   455.3747   383   369.4489   402.6031   −3.02E−01   −2.50E−01   1   Unchanged Low       O95571   G22ef3   protein expressed in thyroid   398.0124   507   369.925   425.0962   −1.06E−01   3.50E−01   1   Unchanged Low       P36941   A09ab7   hymphotoxin beta receptor (TNFF   403.0565   454   370.0343   409.094   −1.23E−01   1.72E−01   1   Unchanged Low       P49790   F11cd5   nucleoporin 153 kD   264.6175   316   370.2793   317.116   4.85E−01   2.58E−01   1   Unchanged Low       Q99607   C06ab4   E74-like factor 4 (ets domain trar   267.135   268   371.3515   302.1703   4.75E−01   4.79E−03   1   Unchanged Low       Q9UIV1   H05cd8   CCR4-NOT transcription comple;   201.0959   465   371.6771   345.9619   8.86E−01   1.21E+00   1   Unchanged Low       Q9Y3E4   O13ef2   CGI-146 protein   107.5317   262   371.8333   247.1535   1.79E+00   1.29E+00   1   Unchanged Low       P19367   D17ab3   hexokinase 1   512.0647   215   371.9817   366.4437   −4.61E−01   −1.25E+00   1   Unchanged Low       Q14250   J15cd5   enigma (LIM domain protein)   229.1944   218   371.9927   272.9152   6.99E−01   −7.52E−02   1   Unchanged Low       Q9UL33   B20ef2   unknown   343.1533   636   372.4427   450.4535   1.18E−01   8.90E−01   1   Unchanged Low       Q15019   H03ef5   neural precursor cell expressed;   489.0601   274   372.9279   378.666   −3.91E−01   −8.36E−01   1   Unchanged Low       Q13084   H05cd6   melanoma-associated antigen re   421.8259   278   373.0512   357.6504   −1.77E−01   −6.01E−01   1   Unchanged Low       Q9UMR2   O18cd7   DEAD/H (Asp-Glu-Ala-Asp/His) t   383.654   423   373.0622   393.1434   −4.04E−02   1.40E−01   1   Unchanged Low       P55855   H06cd2   SMT3 suppressor of mif two 3 ho   454.9011   444   373.596   424.0867   −2.84E−01   −3.58E−02   1   Unchanged Low       Q13155   G20cd4   JTV1 gene   322.6641   409   373.7416   368.4293   2.12E−01   3.42E−01   1   Unchanged Low       P78371   H11cd6   chaperonin containing TCP1; sut   480.5464   430   374.014   428.2475   −3.62E−01   −1.60E−01   1   Unchanged Low       P08173   P17ab3   cholinergic receptor; muscarinic   444.2461   514   374.4117   444.3189   −2.47E−01   2.11E−01   1   Unchanged Low       O60478   E02cd2   transmembrane 7 superfamily m             274.7639   438   374.61   362.4989   4.47E−01   6.73E−01   1   Unchanged Low       O60429   D16gh4   hypothetical protein FLJ12886   142.8322   257   375.0573   258.282   1.39E+00   8.47E−01   1   Unchanged Low       O75935   O04cd7   dynaclin 3 (p22)   408.9698   432   375.1224   405.4281   −1.25E−01   7.97E−02   1   Unchanged Low       Q13147   J05ab2   abl-interactor 2   299.098   249   375.379   307.9098   3.28E−01   −2.63E−01   1   Unchanged Low       Q9NPH4   E14gh3   LUC7-like ( S. cerevislae )   207.38   302   376.3768   295.4166   8.60E−01   5.45E−01   1   Unchanged Low       Q9UJ96   C13cd8   potassium voltage-gated channe   582.717   448   376.4373   468.9343   −6.30E−01   −3.80E−01   1   Unchanged Low       P17081   C13ef6   likely ortholog of mouse TC10-al             293.1604   417   376.4996   362.2816   3.61E−01   5.09E−01   1   Unchanged Low       P11166   J05ef5   solute carrier family 2 (facilltated   351.7333   393   376.564   373.8343   9.84E−02   1.61E−01   1   Unchanged Low       Q14820   D12ef6   splicing factor 1   382.846   408   376.7779   389.2167   −2.30E−02   9.19E−02   1   Unchanged Low       Q92935   I06ab5   exostoses (multiple)-like 1   659.9005   276   376.8548   437.6869   −8.08E−01   −1.26E+00   1   Unchanged Low       P31749   E20ef6   v-akt murine thymorna viral onco             385.4669   303   376.9169   355.1851   −3.24E−02   −3.46E−01   1   Unchanged Low       Q13454   L05cd7   Putative prostate cancer tumor s             326.9146   363   377.0852   355.5691   2.06E−01   1.50E−01   1   Unchanged Low       P35520   C24ab3   cystathionine-beta-synthase   70.85109   68.1   377.1148   172.0203   2.41E+00   −5.72E−02   1   Unchanged Low       P53602   M01ab7   mevalonate (diphospho) decarbc   682.0309   178   378.114   412.6357   −8.51E−01   −1.94E−00   1   Unchanged Low       Q9H7G3   C04gh6   mitochondrial ribosomal protein              333.6677   207   378.1396   306.3867   1.81E−01   −6.86E−01   1   Unchanged Low       Q13123   C06ab7   IK cytokine; down-regulator of HI   257.7332   439   378.1806   358.3456   5.53E−01   7.69E−01   1   Unchanged Low       O14744   G14cd6   SKB1 homolog ( S. pombe )   348.0026   410   378.4165   378.8177   1.21E−01   2.37E−01   1   Unchanged Low       Q9Y566   D16ef8   SH3 and multiple ankyrin repeat   209.2687   281   379.5197   290.0718   8.59E−01   4.27E−01   1   Unchanged Low       Q9BUJ9   A03gh7   Mov10; Moloney leukemia virus   385.0517   472   380.308   412.4352   −1.79E−02   2.94E−01   1   Unchanged Low       P51790   I02ab5   chloride channel 3   330.2251   237   380.3105   315.7621   2.04E−01   −4.80E−01   1   Unchanged Low       O14547   J09cd6   PRP8 pre-mRNA processing fact   239.0005   256   380.5886   291.9777   6.71E−01   1.01E−01   1   Unchanged Low       Q99753   A05cd7   cisplatin resistance associated   257.1873   397   380.7894   345.0384   5.66E−01   6.27E−01   1   Unchanged Low       Q9NQC8   H15gh4   hypothetical protein LOC58912   185.2607   276   381.0416   280.7773   1.04E−00   5.75E−01   1   Unchanged Low       O43919   M01ef6   linker for activation of T cells   206.6586   105   381.2059   230.823   8.83E−01   −9.82E−01   1   Unchanged Low       P78345   F15cd6   ribonuclease P (38 kD)   321.791   530   381.5687   411.2575   2.46E−01   7.21E−01   1   Unchanged Low       P54257   A03ef5   huntingtin-associated protein 1(             450.2874   322   382.6029   384.9948   −2.35E−01   −4.83E−01   1   Unchanged Low       Q9Y3F4   G18cd7   unr-interacting protein   390.9437   335   382.6142   369.3734   −3.11E−02   −2.25E−01   1   Unchanged Low       P29536   F14cd7   lelomodin 1 (smooth muscle)   343.3731   209   382.9438   311.936   1.57E−01   −7.13E−01   1   Unchanged Low       O75925   K03cd4   protein inhibitor of activated STA   423.9992   606   383.7943   471.2944   −1.44E−01   5.15E−01   1   Unchanged Low       Q9UMX5   J23ef4   secreted protein of unknown fun             344.8668   306   384.5676   345.2233   1.57E−01   −1.71E−01   1   Unchanged Low       Q9UMZ9   N02cd7   interleukin enhancer binding fact   348.7866   278   384.7729   337.1554   1.42E−01   −3.28E−01   1   Unchanged Low       Q92905   P03ef6   COP9 constitutive photomorphog   257.5597   392   386.1452   345.1985   5.84E−01   6.06E−01   1   Unchanged Low       Q9NSD7   L20ef1   G-protein coupled receptor SALF   734.6282   277   386.7193   466.2798   −9.26E−01   −1.40E+00   1   Unchanged Low       Q9P2W3   G01ef3   guanine nucleotide binding prote   70.71144   81.4   386.7442   179.6321   2.45E+00   2.04E−01   1   Unchanged Low       Q9BV17   N14gh5   mitochondrial ribosomal protein              367.7177   520   386.9198   424.8293   7.34E−02   4.99E−01   1   Unchanged Low       Q9Y4L1   B23cd6   oxygen regulated protein (150 kD   413.0575   372   387.5372   390.9975   −9.20E−02   −1.49E−01   1   Unchanged Low       Q02363   F18ab7   inhibitor of DNA binding 2; domin   484.7132   359   388.2552   410.6421   −3.20E−01   −4.33E−01   1   Unchanged Low       Q9Y5J8   E06cd8   translocase of inner mitochondris   440.2763   542   388.4554   456.8557   −1.81E−01   2.99E−01   1   Unchanged Low           E22ef1   G protein-coupled receptor 26   499.1316   450   389.582   446.2248   −3.57E−01   −1.50E−01   1   Unchanged Low       Q99501   N11cd6   growth arrest-specific 2 like 1   359.8065   540   389.6398   429.6515   1.15E−01   5.84E−01   1   Unchanged Low       Q00613   M17ef5   heat shock transcription factor 1   363.3847   375   389.8695   376.2292   1.01E−01   4.71E−02   1   Unchanged Low       Q9H5Z1   H16gh4   DEAD/H (Asp-Glu-Ala-Asp/His) t             136.5899   124   389.9835   217.0007   1.51E+00   −1.35E−02   1   Unchanged Low       P09661   P24cd1   small nuclear ribonucleoprotein              441.1409   115   390.2085   315.5701   −1.77E−01   −1.94E+00   1   Unchanged Low       P54709   P05ef5   ATPase; Na+/K+ transporting; b             425.6647   432   391.8135   416.5779   −1.20E−01   2.22E−02   1   Unchanged Low       P13164   M06ef5   interferon induced transmembrar             45.13817   256   392.1204   231.1336   3.12E+00   2.50E+00   1   Unchanged Low       Q9Y6E2   A23ef8   HSPC028 protein   329.8857   363   392.2431   361.6248   2.50E−01   1.37E−01   1   Unchanged Low       Q9NVG2   B13gh3   vacuolar protein sorting 35 (yea             359.0233   557   392.2574   436.0959   1.28E−01   6.34E−01   1   Unchanged Low       P27448   E10ef5   MAP/microtubule affinity-regula             397.7845   369   392.3918   386.4633   −1.97E−02   −1.08E−01   1   Unchanged Low       O15438   P18cd3   ATP-binding cassette; sub-family   618.0409   488   392.8159   499.6643   −6.54E−01   −3.40E−01   1   Unchanged Low       Q9UL48   I04ef2   CK2 interacting protein 1; HQ002   176.5553   215   393.4111   261.8209   1.16E+00   2.88E−01   1   Unchanged Low       O94763   A11cd4   RPB5-mediating protein   333.6215   533   393.9446   420.3384   2.40E−01   6.77E−01   1   Unchanged Low       Q13190   I19cd2   syntaxin 5A   179.6148   235   393.985   269.5995   1.13E+00   3.89E−01   1   Unchanged Low       Q13122   D21ef3   EBNA-2 co-activator (100 kD)   381.3069   375   394.5999   383.7948   4.94E−02   −2.22E−02   1   Unchanged Low       O75312   L01cd4   zinc finger protein 259   348.7542   422   394.8016   388.3905   1.79E−01   2.74E−01   1   Unchanged Low       P37837   D20cd2   transaldolase 1   399.2717   326   395.693   373.7275   −1.30E−02   −2.92E−01   1   Unchanged Low       O75762   G19cd6   ankyrin-like with transmembrane   222.8517   364   395.7427   327.3962   8.28E−01   7.06E−01   1   Unchanged Low       Q99969   K19ef3   retinoic acid receptor responder             283.5705   257   396.0287   312.0672   4.62E−01   −1.44E−01   1   Unchanged Low       Q9UNP2   H15cd2   solute carrier family 1 (neutral an   149.1019   138   396.5014   227.7665   1.41E+00   −1.15E−01   1   Unchanged Low       P56524   C23cd6   histone deacetylase 4   328.6037   303   397.1317   342.9334   2.73E−01   −1.17E−01   1   Unchanged Low       Q9H644   C19gh6   hypothetical protein MGC5585   140.9811   228   397.2624   255.3931   1.49E+00   6.93E−01   1   Unchanged Low       Q13627   O19ab4   dual-specificity tyrosine-(Y)-phos   498.484   327   397.3922   407.7774   −3.27E−01   −6.06E−01   1   Unchanged Low       Q03405   O01ef5   plasminogen activator; urokinase   500.1391   396   396.2456   431.3524   −3.29E−01   −3.38E−01   1   Unchanged Low       Q9NPQ8   L16gh4   likely ortholog of mouse synemb             372.8251   443   398.4083   404.6217   9.57E−02   2.48E−01   1   Unchanged Low       Q15375   A10ab5   EphA7   243.0574   290   396.5414   310.569   7.13E−01   2.55E−01   1   Unchanged Low       P05114   G04ab7   high-mobility group (nonhistone              196.8334   278   398.7327   291.2748   1.02E+00   4.99E−01   1   Unchanged Low       Q9UKU4   C13ef2   retinal short-chain dehydrogenas   370.8225   497   399.4413   422.4244   1.07E−01   4.23E−01   1   Unchanged Low       P08195   E21ab7   solute carrier family 3 (activators   442.5453   345   399.5678   395.768   −1.47E−01   −3.58E−01   1   Unchanged Low       Q15545   J11cd2   TAF7 RNA polymerase II; TATA   400.689   526   401.1308   442.5426   1.59E−03   3.92E−01   1   Unchanged Low           D24gh8   hypothetical protein FLJ14511   246.3293   225   401.3816   290.8781   7.04E−01   −1.31E−01   1   Unchanged Low       Q05397   L20ef5   PTK2 protein tyrosine kinase 2   389.8718   440   401.4713   410.2909   4.23E−02   1.73E−01   1   Unchanged Low       Q9Y6G1   C21ef8   PTD011 protein   434.6906   483   401.5119   439.8467   −1.15E−01   1.53E−01   1   Unchanged Low       P41212   O23ef5   ets variant gene 6 (TEL oncogen   315.7331   502   401.8428   406.6035   3.48E−01   6.70E−01   1   Unchanged Low       O14737   G05cd5   programmed cell death 5   498.729   430   402.3091   443.7457   −3.10E−01   −2.13E−01   1   Unchanged Low       Q9UHB9   A10ef3   signal recognition particle 68 kD   212.5357   247   402.3276   287.2236   9.21E−01   2.16E−01   1   Unchanged Low       Q96D21   C20ef8   RASD family; member 2   395.909   486   402.4304   427.9499   2.36E−02   2.94E−01   1   Unchanged Low       Q9Y4I1   J05ef1   myosin VA (heavy polypeptide 1             371.5954   353   402.453   375.8247   1.15E−01   −7.23E−01   1   Unchanged Low       Q9Y5L4   L14ef7   translocase of inner mitochondri             291.7019   369   404.0738   354.9111   4.70E−01   3.39E−01   1   Unchanged Low       O75439   N22cd4   peptidase (mitochondiral proces             512.9004   184   404.5715   367.0789   −3.42E−01   −1.48E+00   1   Unchanged Low       P55010   K22ab4   eukaryotic translation initiation fa   427.4989   296   405.4996   376.3076   −7.62E−02   −5.31E−01   1   Unchanged Low       Q9BY44   G10gh8   CDA02 protein   453.6064   401   405.956   420.1404   −1.60E−01   −1.78E−01   1   Unchanged Low       Q13164   B21ef5   mitogen-activated protein kinase   209.1026   256   406.234   290.5304   9.58E−01   2.93E−01   1   Unchanged Low       P53667   P08ab6   LIM domain kinase 1   359.4655   392   406.5183   386.0829   1.77E−01   1.26E−01   1   Unchanged Low       Q9UNH6   F05ef2   sorting nexin 7   479.6898   396   406.7812   427.3762   −2.38E−01   −2.78E−01   1   Unchanged Low       O00258   K17cd4   tryptophan rich basic protein   339.3172   500   407.1504   415.5431   2.63E−01   5.60E−01   1   Unchanged Low       Q9Y3I0   I12ef3   hypothetical protein   458.2693   546   407.2408   470.3717   −1.70E−01   2.52E−01   1   Unchanged Low       Q9Y368   D13cd8   parvin; beta   114.232   159   407.3882   226.9908   1.83E+00   4.80E−01   1   Unchanged Low       P14866   H13ab8   heterogeneous nuclear ribonucle   442.5489   274   407.4025   374.6383   −1.19E−01   −6.92E−01   1   Unchanged Low       Q13885   K01cd3   tubulin; beta polypeptide   441.2669   413   407.8683   420.8456   −1.14E−01   −9.41E−02   1   Unchanged Low       O43765   J06cd1   small glutamine-rich tetratricope             378.9705   438   408.6453   408.6939   1.09E−01   2.10E−01   1   Unchanged Low       O14632   B12ef4   homeodomain interacting protein   394.449   535   408.8773   446.1081   5.18E−02   4.40E−01   1   Unchanged Low       P31939   L10ab2   5-aminoimidazole-4-carboxamid             501.3028   386   409.3069   432.286   −2.92E−01   −3.76E−01   1   Unchanged Low       P28331   P18ab8   NADH dehydrogenase (ubiquino             490.4347   417   409.3283   438.7901   −2.61E−01   −2.35E−01   1   Unchanged Low       P41970   P05ef6   ELK3; ETS-domain protein (SRF   205.9453   359   410.8037   325.3706   9.96E−01   8.03E−01   1   Unchanged Low       Q92973   J22ab6   karyopherin (importin) beta 2   393.6551   234   410.9425   346.1733   6.20E−02   −7.51E−01   1   Unchanged Low       P36507   J10ef5   mitogen-activated protein kinase   395.22   437   411.4052   414.6953   5.79E−02   1.46E−01   1   Unchanged Low       Q16512   F21ab8   protein kinase C-like 1   456.2727   486   411.8245   451.4528   −1.48E−01   9.18E−02   1   Unchanged Low       O43447   M08cd6   peptidyl prolyl isomerase H (cyc             179.441   222   411.9165   271.0162   1.20E+00   3.05E−01   1   Unchanged Low       P30040   M13ef3   chromosome 12 open reading fr             346.6792   296   412.2064   351.5665   2.50E−01   −2.29E−01   1   Unchanged Low       O95399   C19cd7   urotensin 2   452.0721   366   413.1451   410.4914   −1.30E−01   −3.04E−01   1   Unchanged Low           M01ab3   UDP-Gal:betaGal beta 1:3-galac   499.9529   290   413.3454   401.0113   −2.74E−01   −7.87E−01   1   Unchanged Low       Q12792   N11ab8   protein tyrosine kinase 9   476.3952   364   413.4208   416.007   −2.05E−01   −3.87E−01   1   Unchanged Low       Q14318   J02cd7   FK506 binding protein 8 (38 kD)   461.2322   432   413.4238   435.6453   −1.58E−01   −9.35E−02   1   Unchanged Low       O75955   N10cd5   fiotillin 1   304.6674   310   415.4364   343.498   4.47E−01   2.68E−02   1   Unchanged Low       Q9BVY8   B09gh7   hypothetical protein MGC5499   490.2382   417   416.02   440.9559   −2.37E−01   −2.35E−01   1   Unchanged Low       Q16288   O19ef5   neurotrophic tyrosine kinase; rec   126.7467   186   416.4128   243.0358   1.72E+00   5.53E−01   1   Unchanged Low       O75380   J20ab8   NADH dehydrogenase (ubiquino             449.5778   413   416.4836   426.4999   −1.10E−01   −1.21E−01   1   Unchanged Low       Q9BY51   B15gh8   hypothetical protein GL009   429.1998   354   417.3575   400.0464   −4.04E−02   −2.80E−01   1   Unchanged Low       Q9BVK3   E19gh6   hypothetical protein MGC2463   452.5828   387   417.7046   422.5145   −1.47E−01   −2.56E−01   1   Unchanged Low       Q9P0N3   A24ef2   hypothetical protein FLJ10597   137.7487   289   417.999   281.424   1.60E+00   1.07E+00   1   Unchanged Low       P24534   D03ab4   eukaryotic translation elongation   347.2405   328   418.0152   364.5026   2.68E−01   −8.11E−02   1   Unchanged Low       P49336   C01ab4   cyclin-dependent kinase 8   426.3751   281   418.121   375.2575   −2.82E−02   −6.00E−01   1   Unchanged Low       P34130   P16cd2   neurotrophin 5 (neurotrophin 4/5             327.4146   223   418.6011   323.0643   3.54E−01   −5.53E−01   1   Unchanged Low       O75425   P06gh5   hypothetical protein AF053356_             340.4357   339   419.3637   366.1692   3.01E−01   −7.34E−03   1   Unchanged Low       Q15293   F16ab8   reticulocalbin 1; EF-hand calciu             241.6383   250   420.5597   304.1243   7.99E−01   5.01E−02   1   Unchanged Low       O95376   D08ab2   ariadne homolog 2 ( Drosophila )   254.1122   322   420.8229   332.2465   7.28E−01   3.41E−01   1   Unchanged Low       O75489   J16ab8   NADH dehydrogenase (ubiquino             375.7034   327   422.3772   375.1108   1.69E−01   −1.99E−01   1   Unchanged Low       P28482   B15ef5   mitogen-activated protein kinase   493.835   452   422.4625   456.1064   −2.25E−01   −1.28E−01   1   Unchanged Low       P20823   B09cd1   transcription factor 1; hepatic; LF   322.4782   527   423.4405   424.3654   3.93E−01   7.09E−01   1   Unchanged Low       O15250   I04cd4   X-prolyl aminopeptidase (amino             524.8188   542   423.7387   496.7532   −3.09E−01   4.57E−02   1   Unchanged Low       P55769   P22ab8   NHP2 non-histone chormosome              137.3557   479   424.0031   346.68   1.63E+00   1.80E+00   1   Unchanged Low       O94817   N21ab2   APG12 autophagy 12-like (S. ce             631.6055   402   424.3577   485.9574   −5.74E−01   −8.52E−01   1   Unchanged Low       O75352   K08cd5   mannose-P-dolichol utilization d             272.444   523   424.8266   406.7998   6.41E−01   9.41E−01   1   Unchanged Low       Q16585   I16cd1   sarcoglycan; beta (43 kD dystrop             256.2113   293   425.1172   324.9166   7.31E−01   1.96E−01   1   Unchanged Low       Q9H7X7   B16gh5   hypothetical protein FLJ14117   261.9578   463   425.3725   383.5805   6.99E−01   8.23E−01   1   Unchanged Low       O15173   I16cd6   progesterone receptor membrane   295.0481   244   425.8728   321.6602   5.29E−01   −2.74E−01   1   Unchanged Low       Q9GZX9   A16gh4   twisted gastrulation   84.61732   147   426.1124   219.3062   2.33E+00   7.99E−01   1   Unchanged Low       Q16594   M09cd2   TAF9 RNA polymearase II; TATA   171.3507   520   426.7606   372.6331   1.32E+00   1.60E+00   1   Unchanged Low       O00479   O17gh1   high-mobility group (nonhistone              265.695   354   426.7642   348.9168   6.84E−01   4.15E−01   1   Unchanged Low       P54760   C22ab5   EphB4   528.7066   413   427.0543   456.4179   −3.08E−01   −3.55E−01   1   Unchanged Low       P25490   F06ef6   YY1 transcription factor   481.2844   530   427.184   479.4548   −1.72E−01   1.39E−01   1   Unchanged Low       Q9UJY0   B07ef1   putative necleotide binding prote             505.9493   431   427.3544   454.8441   −2.44E−01   −2.31E−01   1   Unchanged Low       Q09668   A22ef3   AHNAK nucleoprotein (desmoyol   392.0671   399   427.3828   406.041   1.24E−01   2.41E−02   1   Unchanged Low       O15305   P22ab7   phosphomannomutase 2   325.0777   480   428.3778   411.2528   3.98E−01   5.63E−01   1   Unchanged Low       O60492   M09ab4   7-dehydrocholestrol reductase   388.5228   213   428.5923   343.3316   1.42E−01   −8.68E−01   1   Unchanged Low       Q9UND3   G11cd6   nuclear pore complex interacting   280.8175   312   428.5952   340.6147   6.10E−01   1.54E−01   1   Unchanged Low       Q9HB15   M15gh5   potassium channel: subfamily K:   473.5589   408   428.9308   436.9131   −1.43E−01   −2.14E−01   1   Unchanged Low       Q9Y3B4   H23ef2   CGI-110 protein   290.9669   331   429.1497   350.4808   5.61E−01   1.87E−01   1   Unchanged Low       Q14107   F05ef5   D123 gene product   387.0465   405   429.9331   407.3091   1.52E−01   6.52E−02   1   Unchanged Low       P52435   A22cd1   polymerase (RNA) II (DNA direct   527.0446   461   429.9488   472.7272   −2.94E−01   −1.93E−01   1   Unchanged Low       Q9Y262   L11ef2   eukaryotic translation initiation fa             591.5767   311   430.6788   444.385   −4.58E−01   −9.28E−01   1   Unchanged Low       P10163   L20cd2   proline-rich protein BstNI subfam             521.4154   251   431.1299   401.2036   −2.74E−01   −1.05E+00   1   Unchanged Low       P38378   F01cd8   protein transport protein SEC61              635.5838   369   431.9958   478.7225   −5.57E−01   −7.86E−01   1   Unchanged Low       P48735   B06ab6   Isocitrate dehydrogenase 2 (NA             600.2178   338   432.1616   456.8577   −4.74E−01   −8.28E−01   1   Unchanged Low       Q9NPF5   F02gh4   DNA methyltranferase 1-associ             451.5343   382   432.3473   421.964   −6.26E−02   −2.41E−01   1   Unchanged Low       O14616   K22cd4   zinc finger protein-like 1   194.5871   348   432.4885   324.9789   1.15E+00   8.38E−01   1   Unchanged Low       Q00839   A12ab7   heterogeneous nuclear ribonucle             416.5145   410   432.5188   419.7665   5.44E−02   −2.18E−02   1   Unchanged Low       O95563   J15ef8   DKFZP564B167 protein   390.848   389   432.8082   404.2972   1.47E−01   −5.96E−03   1   Unchanged Low       Q92974   I03cd6   rho/rac guanine nucleotide exch             142.3392   124   433.2388   233.2947   1.61E+00   −1.95E−01   1   Unchanged Low       Q9UEE5   M07cd5   serine/threonine kinase 17a (apc             397.8599   472   433.4221   434.4129   1.24E−01   2.46E−01   1   Unchanged Low       Q9NX81   O19gh3   BTB (POZ) domain containing 2   175.3887   206   433.4811   271.6819   1.31E+00   2.33E−01   1   Unchanged Low       Q9NXF9   O01gh3   O-linked mannose beta1; 2-N-ac             477.6375   353   434.2927   421.54   −1.37E−01   −4.38E−01   1   Unchanged Low       P98171   F13ef1   Rho GTPase activating protein 4   368.9887   231   435.3585   345.0241   2.39E−01   −6.77E−01   1   Unchanged Low       P56192   I14ab7   methionine-tRNA synthetase   263.0076   295   435.694   331.1505   7.29E−01   1.63E−01   1   Unchanged Low       O95411   K09cd5   TGFB1-induced anti-apoptotic fa             233.3926   310   436.2684   326.6136   9.02E−01   4.10E−01   1   Unchanged Low       P09132   E23cd2   signal recognition particle 19 kD   227.6193   595   436.5994   419.7603   9.38E−01   1.38E+00   1   Unchanged Low       Q92537   O24gh1   KIAA0247 gene product   291.1054   232   437.1141   319.914   5.86E−01   −3.30E−01   1   Unchanged Low       P49761   G03ab4   CDC-like kinase 3   458.9286   562   437.5601   486.0405   −6.88E−02   2.91E−01   1   Unchanged Low       Q9HDC4   O19gh4   junctophilin 3   346.7829   388   439.282   391.3835   3.41E−01   1.62E−01   1   Unchanged Low       P98160   A13ef7   heparan sulfate proteoglycan 2 (             505.6962   372   439.9544   439.0897   −2.01E−01   −4.44E−01   1   Unchanged Low       Q9NQV6   O22gh4   PR domain containing 10   369.157   514   440.5347   441.3923   2.55E−01   4.79E−01   1   Unchanged Low       Q9NRX6   J09gh4   protein x 013   324.5306   345   440.8995   370.1383   4.42E−01   8.82E−02   1   Unchanged Low       O76084   A13cd4   catenin (cadherin-associated pro   471.1305   211   441.7617   374.6479   −9.29E−02   −1.16E+00   1   Unchanged Low       P23197   E19cd7   chromobox homolog 1 (HP1 beta   480.8183   362   441.9595   428.3076   −1.22E−01   −4.09E−01   1   Unchanged Low       Q99439   E10ab6   calponin 2   429.1961   304   442.4148   391.978   4.38E−02   −4.96E−01   1   Unchanged Low       Q14656   O04ef6   dystonia 1: torsion (autosomal d             415.3893   533   442.9429   463.6417   9.27E−02   3.59E−01   1   Unchanged Low       Q9NPJ3   P04gh4   uncharacterized hypothalamus p   411.0811   430   443.2575   428.1718   1.09E−01   6.55E−02   1   Unchanged Low       P41226   B10ef7   ubiquitin-activating enzyme E1-             298.6597   342   443.334   361.2685   5.70E−01   1.95E−01   1   Unchanged Low       Q9Y478   C24cd1   protein kinase; AMP-activated; b             306.0158   165   443.5049   304.7576   6.35E−01   −8.93E−01   1   Unchanged Low           P06cd8   nodal homolog (mouse)   349.4202   252   443.7188   348.2928   3.45E−01   −4.73E−01   1   Unchanged Low       Q12904   O06ef7   small inducible cytokine subfamil             374.6683   459   445.5171   426.5346   2.50E−01   2.94E−01   1   Unchanged Low       P20264   C02cd1   POU domain; class 3; transcription   458.6994   302   447.8929   402.9521   −3.44E−02   −6.02E−01   1   Unchanged Low       Q15428   B11cd4   splicing factor 3a; subunit 2; 66 k             284.0454   334   448.6652   355.7289   6.60E−01   2.36E−01   1   Unchanged Low       P49771   G06ef6   fms-related tyrosine kinase 3 liga             449.6827   417   452.1329   439.4747   7.64E−03   −1.10E−01   1   Unchanged Low       P49005   A18cd1   polymerase (DNA directed); delt             363.5225   232   452.6832   349.3417   3.16E−01   −6.49E−01   1   Unchanged Low       Q99879   M14gh6   H2B histone family; member E   325.9523   483   452.8012   420.4323   4.74E−01   5.69E−01   1   Unchanged Low       P49821   G20cd1   NADH dehydrogenase (ubiqunio             511.5488   392   454.6223   452.5721   −1.70E−01   −3.86E−01   1   Unchanged Low       P10644   H22ef5   protein kinase; cAMP-dependent   420.8225   518   454.8256   464.5909   1.12E−01   3.00E−01   1   Unchanged Low       Q9Y5J4   L17gh6   pyrroline 5-carboxylate reductase   145.6987   303   455.1667   301.448   1.64E+00   1.06E+00   1   Unchanged Low       P31040   K02cd2   succinate dehydrogenase compl             671.3369   351   456.2212   492.7974   −5.57E−01   −9.36E−01   1   Unchanged Low       Q9UHA2   F04ef8   synovial sarcoma translocation g   438.6951   480   456.469   458.4094   5.73E−02   1.30E−01   1   Unchanged Low       Q9UBF6   C02ef3   ring finger protein 7   315.6541   400   456.9368   390.7186   5.34E−01   3.40E−01   1   Unchanged Low       Q9Y5S2   C21cd6   CDC42 binding protein kinase b             386.9683   447   456.9709   430.2759   2.40E−01   2.08E−01   1   Unchanged Low       P20809   H07ef7   interleukin 11   399.048   140   458.1544   332.3748   1.99E−01   −1.51E+00   1   Unchanged Low       Q13526   F21ef5   protein (peptidyl-prolyl cls/trans              333.4194   460   458.2237   417.3666   4.59E−01   4.66E−01   1   Unchanged Low       Q9NWQ9   H01gh2   hypothetical protein FLJ20671   430.7122   577   458.2293   488.6936   8.93E−02   4.22E−01   1   Unchanged Low       Q9Y6J0   E05cd8   calcineurin binding protein 1   474.3964   117   458.7489   350.127   −4.84E−02   −2.02E+00   1   Unchanged Low       Q9Y4Z6   B13cd7   vacuolar protein sorting 45A (yea             115.1679   276   458.8586   283.3006   1.99E+00   1.26E+00   1   Unchanged Low       Q01433   G02ab8   adenosine monophosphate dean   352.5251   390   459.2935   400.6864   3.82E−01   1.47E−01   1   Unchanged Low       O43181   M07ab8   NADH dehydrogenase (ubiquino             417.4586   432   460.2425   436.6589   1.41E−01   5.03E−02   1   Unchanged Low       Q9NWT5   D15gh2   hypothetical protein FLJ20618   354.3599   523   460.3326   445.8286   3.77E−01   5.61E−01   1   Unchanged Low       O75431   P19cd6   metaxin 2   282.4791   443   460.352   395.1258   7.05E−01   6.48E−01   1   Unchanged Low       P09543   A18gh7   2′;3′-cyclic nucleotide 3′ phospho             258.2862   510   462.033   409.9513   8.39E−01   9.80E−01   1   Unchanged Low       Q9BTE1   B05gh8   dynactin 4   562.6142   460   462.4054   494.9234   −2.83E−01   −2.91E−01   1   Unchanged Low       P16152   H14ab5   carbonyl reductase 1   234.3184   240   463.6916   312.8541   9.85E−01   3.30E−02   1   Unchanged Low       O15121   D06cd3   degenerative spermatocyte homo             264.7024   270   464.4612   333.1906   8.11E−01   3.08E−02   1   Unchanged Low       O60909   E09ab3   UDP-Gal: betaGlcNAc beta 1; 4-             365.8881   379   464.9697   403.197   3.46E−01   4.98E−02   1   Unchanged Low       O75223   C11gh6   hypothetical protein MGC3077   493.9011   276   465.7709   411.9427   −8.46E−02   −8.39E−01   1   Unchanged Low       Q9BQA1   K03gh6   MEP50 protein   379.1943   303   466.1997   382.8783   2.98E−01   −3.22E−01   1   Unchanged Low       O43427   F20cd4   fibroblast growth factor (acidic)              323.6471   325   466.8724   371.8858   5.29E−01   6.63E−03   1   Unchanged Low       Q9BWG6   A15gh6   hypothetical protein MGC3180   309.3486   596   468.0924   457.7257   5.98E−01   9.45E−01   1   Unchanged Low       Q9Y6R2   M04cd6   chromosome 4 open reading frar   337.7358   352   469.9502   386.6911   4.77E−01   6.13E−02   1   Unchanged Low       Q9HBK7   M07gh4   NPD007 protein   367.4893   489   471.1924   442.4205   3.59E−01   4.11E−01   1   Unchanged Low       P52758   E04ef7   translational inhibitor protein p14   324.9333   318   471.2741   371.3427   5.36E−01   −3.19E−02   1   Unchanged Low       P47897   E19cd1   glutaminyl-tRNA synthetase   400.1718   364   472.5359   412.2837   2.40E−01   −1.36E−01   1   Unchanged Low       Q9BWQ6   P20gh5   hypothetical protein MGC3262   288.8083   483   473.0084   415.0843   7.12E−01   7.43E−01   1   Unchanged Low       P35325   H22cd5   small proline-rich protein 2B   390.5307   584   474.2762   483.0992   2.80E−01   5.82E−01   1   Unchanged Low       Q9HA68   O23gh5   hypothetical protein FLJ12154   556.3676   383   474.593   471.3877   −2.29E−01   −5.38E−01   1   Unchanged Low       P49368   P16ab5   deoxyhypusine synthase   458.6886   481   477.1999   472.2313   5.17E−02   6.79E−02   1   Unchanged Low       Q9UKZ7   J18ef1   colon carcinoma related protein   505.0182   450   478.4787   477.7496   −7.79E−02   −1.67E−01   1   Unchanged Low       P01730   K15ef5   CD4 antigen (p55)   516.4046   432   478.8033   475.788   −1.09E−01   −2.57E−01   1   Unchanged Low       P20674   L06cd4   cytochrome c oxidase subunit Va   512.4055   372   480.2708   454.7764   −9.34E−02   −4.63E−01   1   Unchanged Low       Q12828   H02ef6   far upstream element (FUSE) bin   462.592   312   480.5079   418.2868   5.48E−02   −5.69E−01   1   Unchanged Low       Q9Y6A4   J18ef3   similar to mouse Git3 or D. malar   359.9248   485   480.8661   442.0882   4.18E−01   4.32E−01   1   Unchanged Low       O60888   B09ef2   divalent cation tolerant protein C   298.6981   304   481.136   361.3342   6.88E−01   2.62E−02   1   Unchanged Low       O75716   F08cd3   serine/threonine kinase 16   384.1875   379   481.1652   408.0382   4.02E−01   5.66E−02   1   Unchanged Low       P30711   E18ef7   glutathione S-transferase theta 1   327.8121   533   481.9461   447.6268   5.56E−01   7.02E−01   1   Unchanged Low       Q15008   L03gh1   KIAA0107 gene product   475.6485   506   482.3327   488.0851   2.01E−02   9.00E−02   1   Unchanged Low       P17174   N07ab4   glutamic-oxaloacetic transamina             412.5293   224   484.4384   373.5229   2.32E−01   −8.84E−01   1   Unchanged Low       P13798   K16ab2   N-acylaminoacyl-peptide hydrola   365.1218   351   484.44   400.3314   4.08E−01   −5.51E−02   1   Unchanged Low       Q9P2R8   E15ef4   Misshapen/NIK-related kinase   469.5725   511   484.515   488.4865   4.52E−02   1.23E−01   1   Unchanged Low       Q9UNT1   E20cd7   RAB; member of RAS oncogene   268.916   347   484.9919   366.9843   8.51E−01   3.68E−01   1   Unchanged Low       O75607   L11cd7   nucleophosmin/nucleoplasmin; 3   350.2387   272   485.5671   369.1972   4.71E−01   −3.66E−01   1   Unchanged Low       O94925   B20gh1   glutaminase   410.4357   471   486.8946   456.0458   2.46E−01   1.98E−01   1   Unchanged Low       O95390   A06ab3   growth differentiation factor 11   264.606   324   489.3912   359.3416   8.87E−01   2.92E−01   1   Unchanged Low       O75956   K13cd6   tumor suppressor deleted in oral   524.962   482   489.6212   498.9664   −1.01E−01   −1.22E−01   1   Unchanged Low       O95573   I23ab5   fatty-acid-Coenzyme A ligase; lo             354.1387   174   489.6455   339.2885   4.67E−01   −1.02E+00   1   Unchanged Low       Q9BXH1   N23gh6   Bcl-2 binding component 31   493.3887   433   492.1083   472.8963   −3.75E−03   −1.88E−01   1   Unchanged Low       P13662   L20cd5   nuclear transport factor 2   392.576   479   492.4942   454.7336   3.27E−01   2.67E−01   1   Unchanged Low       Q92793   H05ab5   CREB binding protein (Rubinstel   468.559   474   494.3525   478.8243   7.73E−02   1.53E−02   1   Unchanged Low       Q9P0H6   K23ef4   AD-012 protein   406.4789   469   495.1858   456.7944   2.85E−01   2.06E−01   1   Unchanged Low       Q9P0R3   C05ef3   hypothetical protein HSPC213   339.0916   509   495.2656   447.9021   5.47E−01   5.87E−01   1   Unchanged Low       O75094   E11gh1   slit homolog 3 ( Drosophila )   345.9855   439   496.3812   426.952   5.21E−01   3.42E−01   1   Unchanged Low       Q9P011   P10ef2   non-canonical ubquitin conjugati             460.4398   538   497.256   498.5084   1.11E−01   2.24E−01   1   Unchanged Low       Q92504   M12cd4   HLA class II region expressed g             251.7256   339   497.6138   362.6669   9.83E−01   4.28E−01   1   Unchanged Low       O95190   L12cd8   omithine decarboxylase antizym             421.0592   441   497.6839   453.1247   2.41E−01   6.55E−02   1   Unchanged Low       Q9Y230   N12cd6   RuvB-like 2 ( E. coli )   342.0841   300   497.7767   379.9805   5.41E−01   −1.89E−01   1   Unchanged Low       Q9BSG0   M16gh8   chromosome 2 open reading trar   324.5321   458   497.8462   426.9191   6.17E−01   4.98E−01   1   Unchanged Low       Q9Y368   I17ef2   chromosome 20 open reading tra   278.1968   453   498.3057   409.8539   8.41E−01   7.04E−01   1   Unchanged Low       Q14094   O24ef5   cyclin I   407.6242   354   499.6223   420.31   2.94E−01   −2.05E−01   1   Unchanged Low       P43403   H04ef5   zeta-chain (TCR) associated pro   396.0583   396   500.6282   430.7684   3.38E−01   −1.60E−03   1   Unchanged Low       P52803   H23ef7   ephrin-A5   357.5339   316   501.0718   391.4643   4.87E−01   −1.79E−01   1   Unchanged Low       O95402   E18cd5   cofactor required for Sp1 transcri   106.0683   58.7   501.9814   222.265   2.24E+00   −8.52E−01   1   Unchanged Low       O00233   L23ab8   proteasome (prosome; macropali   581.8818   399   502.2082   494.287   −2.12E−01   −5.45E−01   1   Unchanged Low       Q9H1K6   O18gh7   mesoderm development candidar   432.735   560   502.7516   498.6205   2.16E−01   3.73E−01   1   Unchanged Low       Q9BXL6   K15gh6   caspase recruitment domain prot   425.1251   523   502.8514   483.629   2.42E−01   2.99E−01   1   Unchanged Low       Q9H173   H03gh5   endoplasmic reticulum chaperon             456.5646   449   503.5156   469.6418   1.41E−01   −2.46E−02   1   Unchanged Low       Q9NV83   H03gh3   hypothetical protein FLJ10876   423.9423   497   504.9702   475.4325   2.52E−01   2.30E−01   1   Unchanged Low       P11926   A12ab8   omithine decarboxylase 1   591.3922   362   505.3016   486.3355   −2.27E−01   −7.07E−01   1   Unchanged Low       Q04743   D23ef1   empty spiracles homolog 2 (Dros   531.3866   311   505.7367   449.3322   −7.14E−02   −7.73E−01   1   Unchanged Low       Q98VK2   G11gh6   hypothetical protein MGC2840 sl   388.8682   383   505.9804   425.9595   3.80E−01   −2.18E−02   1   Unchanged Low       O43251   I16ef3   RNA binding motif protein 9   346.6445   530   507.0674   461.1452   5.49E−01   6.12E−01   1   Unchanged Low       Q99829   L13cd4   copine I   355.3783   268   508.4915   377.1688   5.17E−01   −4.09E−01   1   Unchanged Low       O95777   B10ef2   U6 snRNA-associated Sm-like pr   391.981   311   508.8683   403.8183   3.77E−01   −3.36E−01   1   Unchanged Low       Q9UN53   C19ef2   calcium binding protein Cab45 pr   327.721   407   509.3316   414.6963   6.36E−01   3.13E−01   1   Unchanged Low       P24310   F03ab4   cytochrome c oxidase subunit VII   184.0695   288   509.4504   327.1972   1.47E+00   6.46E−01   1   Unchanged Low       Q9H929   N09gh5   hypothetical protein FLJ13055   387.341   500   510.1197   465.7217   3.97E−01   3.67E−01   1   Unchanged Low       P10768   K19ef1   esterase D/formylglutathione hyd   596.3068   102   510.5002   402.8142   −2.24E−01   −2.55E+00   1   Unchanged Low       O95287   D17cd5   golgi autoantigen; golgin subfam   346.1135   560   510.6433   472.3714   5.61E−01   6.95E−01   1   Unchanged Low       Q01105   H18cd1   SET translocation (myeloid leuxe   328.6513   403   511.1477   414.2142   6.37E−01   2.94E−01   1   Unchanged Low       Q9UK45   B08ef2   U6 snRNA-associated Sm-like pr   388.4486   551   511.9386   483.7088   3.98E−01   5.04E−01   1   Unchanged Low       P35611   I17ab2   adducin 1 (alpha)   435.0349   519   512.6447   488.7819   2.37E−01   2.54E−01   1   Unchanged Low       O14681   K22cd5   etoposide-induced mRNA   451.5599   324   516.5292   430.8211   1.94E−01   −4.77E−01   1   Unchanged Low       P80303   A05cd1   nucleobindin 2   296.1418   236   516.7037   349.5918   8.03E−01   −3.28E−01   1   Unchanged Low       Q9NWC0   N19gh2   F-box only protein 4   434.5394   477   517.7728   476.3476   2.53E−01   1.34E−01   1   Unchanged Low       P00367   B06ab5   glutamate dehydrogenase 1   360.6   303   518.2525   394.0342   5.23E−01   −2.50E−01   1   Unchanged Low       O00469   I09ab8   procollagen-lysine; 2-oxoglutarat   735.8327   238   518.6446   497.4006   −5.05E−01   −1.63+00   1   Unchanged Low       Q9UI04   M18ef4   mitochondrial ribosomal protein I   364.1383   336   520.377   406.7523   5.15E−01   −1.17E−01   1   Unchanged Low       P20338   N08ab8   RAB4A; member RAS oncogene   487.9427   457   520.7608   488.5317   9.39E−02   −9.49E−02   1   Unchanged Low       Q9HCU8   I19gh4   polymerase (DNA-directed); delt             513.52   431   522.5153   489.0161   2.51E−02   −2.53E−01   1   Unchanged Low       P00519   I06ef5   v-abi Abelson murine leukemia v   232.4636   301   522.7624   352.0574   1.17E+00   3.73E−01   1   Unchanged Low       Q13880   O02cd5   brain and reproductive organ-ex             572.4849   263   523.9906   453.0588   −1.28E−01   −1.12E+00   1   Unchanged Low       P25789   L13ef7   proteasome (prosome; macropali   436.5895   534   526.397   498.9408   2.70E−01   2.90E−01   1   Unchanged Low       O43805   J16cd3   Sjogren&#39;s syndrome nuclear auto   368.0123   539   526.5215   477.7167   5.17E−01   5.50E−01   1   Unchanged Low       O75817   A13cd6   POP7 (processing of precursor;   375.1187   433   526.6432   445.0255   4.89E−01   2.08E−01   1   Unchanged Low       Q9UBI1   N11cd7   BUP protein   337.1018   428   526.9646   430.701   6.45E−01   3.45E−01   1   Unchanged Low       P03950   G12ab2   angiogenin; ribonuclease; RNase   395.0198   200   527.7882   374.4251   4.18E−01   −9.79E−01   1   Unchanged Low       P78423   F20cd1   small inducible cytokine subfamily   201.965   747   530.2357   493.2272   1.39E+00   1.89E+00   1   Unchanged Low       Q9P1D0   E07gh4   hypothetical protein PRO2533   58.04051   73.3   531.5331   220.9467   3.20E+00   3.36E−01   1   Unchanged Low       P03999   K05ab3   opsin 1 (cone pigments); short-w   116.5093   37.9   532.8048   229.0786   2.19E+00   −1.62E+00   1   Unchanged Low       O95793   M22cd2   staufen; RNA binding protein (Dr   417.7687   498   534.8626   483.6536   3.56E−01   2.54E−01   1   Unchanged Low       P22750   M05ef2   RAB4B; member RAS oncogene   297.3584   346   538.4665   393.9782   8.57E−01   2.19E−01   1   Unchanged Low           B06gh8   ubiquitin UBF-fi   431.0731   472   540.8482   481.1517   3.27E−01   1.29E−01   1   Unchanged Low       Q9NRX8   J15gh4   oxidoreductase UCPA   168.7047   523   544.0864   411.9671   1.69E+00   1.63E+00   1   Unchanged Low       Q9UHQ3   J20gh4   stromal cell protein   469.8784   214   548.1893   410.1503   2.17E−01   −1.13E+00   1   Unchanged Low       Q96S52   J22gh8   phosphatidylinositol glycan; clas             404.9498   287   548.8906   412.8095   4.34E−01   −4.99E−01   1   Unchanged Low       Q9H3F6   C24gh8   MSTP028 protein   442.9007   396   549.0707   462.5636   3.10E−01   −1.63E−01   1   Unchanged Low       P37198   K03cd8   nucleoporin 62 kD   428.2961   499   550.8083   492.7531   3.63E−01   2.21E−01   1   Unchanged Low       Q9H1D4   B05gh4   arginyl aminopeptidase (aminop             430.3273   477   551.8541   486.2744   3.59E−01   1.47E−01   1   Unchanged Low       O75350   K04cd5   glycoprotein; synaptic 2   480.7082   436   552.8489   489.9278   2.02E−01   −1.40E−01   1   Unchanged Low       Q9P024   D16ef3   Huntingtin Interacting protein K   369.5132   480   553.5493   467.714   5.83E−01   3.78E−01   1   Unchanged Low       Q9Y224   H21ef2   CGI-99 protein   449.089   472   554.6607   492.0453   3.05E−01   7.30E−02   1   Unchanged Low       Q13361   O12cd3   Microfibril-associated glycoprotel   194.28   354   557.066   368.553   1.52E+00   8.67E−01   1   Unchanged Low       Q02535   F01ef1   inhibitor of DNA binding 3; domir   84.05787   174   559.513   272.6788   2.73E+00   1.05E+00   1   Unchanged Low       O95864   L24cd4   fatty acid desaturase 2   298.4502   113   559.6571   323.8122   9.07E−01   −1.40E+00   1   Unchanged Low       P53621   H16ab4   coatomer protein complex; subur   409.2779   471   560.6313   480.1571   4.54E−01   2.01E−01   1   Unchanged Low       P35638   N03ab4   DNA-damage-inducible transcrip   322.5942   318   565.361   401.9484   8.09E−01   −2.12E−02   1   Unchanged Low       P22307   D22cd1   sterol carrier protein 2   354.3674   356   569.1558   426.421   6.84E−01   5.58E−03   1   Unchanged Low       Q92543   D15gh1   KIAA0254 gene product   328.3511   356   569.5472   417.8592   7.95E−01   1.15E−01   1   Unchanged Low       P78330   N06ab8   phosphoserine phosphatase   253.4253   220   569.9825   347.8406   1.17E+00   −2.03E−01   1   Unchanged Low       Q9UNX3   G15ef2   ribosomal protein L26-like 1   401.3697   445   572.3441   472.8205   5.12E−01   1.48E−01   1   Unchanged Low       P49169   C10ab2   aldehyde dehydrogenase 9 famil   446.252   277   579.314   434.2707   3.76E−01   −6.87E−01   1   Unchanged Low       Q9ULX0   H03gh6   inorganic pyrophosphatase   488.3446   402   579.6142   489.9828   2.47E−01   −2.81E−01   1   Unchanged Low       O15353   H21cd3   winged-hellx nude   407.9375   497   680.6191   495.2368   5.09E−01   2.85E−01   1   Unchanged Low       Q9NRP2   D21gh4   DC13 protein   382.8544   421   581.5421   461.731   6.03E−01   1.36E−01   1   Unchanged Low       Q16280   E18ef1   cyclic nucleotide gated channel              464.0608   360   584.8035   469.6748   3.34E−01   −3.66E−01   1   Unchanged Low       P04183   C04cd2   thymidine kinase 1; soluble   346.7317   289   588.3101   407.8979   7.63E−01   −2.64E−01   1   Unchanged Low       Q12824   O17ef5   SWI/SNF related; matrix associa   218.8831   554   590.2326   454.3734   1.43E+01   1.34E+00   1   Unchanged Low       Q99719   B09ab8   peanut-like 1 ( Drosophila )   419.5269   410   592.2598   474.0479   4.97E−01   −3.19−02   1   Unchanged Low       P46100   H07ab3   alpha thalassemia/mental retard             309.8648   167   594.3041   356.9983   9.40E−01   −8.93E−01   1   Unchanged Low       Q16610   O05ab5   extracellular matrix protein 1   238.3172   335   596.1691   389.6774   1.32E+00   4.89E−01   1   Unchanged Low       P39656   E23ab6   dolichyl-diphosphoollgosacchari             433.6719   367   598.0668   466.4028   4.64E−01   −2.39E−01   1   Unchanged Low       P53814   G07cd3   smoothelin   517.4102   269   598.16   461.5158   2.09E−01   −9.44E−01   1   Unchanged Low       Q9P0N4   P24ef1   hypothetical protein LOC51260   609.9142   286   601.9324   499.258   −1.90E−02   −1.09E−01   1   Unchanged Low       Q9BXZ1   A02gh7   peptidylprolyl isomerase (cyclopt   465.4301   362   603.8737   477.1895   3.76E−01   −3.62E−01   1   Unchanged Low       Q9Y2Q4   H19ef8   HSPC002 protein   337.5615   391   604.9187   444.641   8.42E−01   2.14E−01   1   Unchanged Low       O15527   A18ab8   8-oxoguanine DNA glycosylase   330.4852   282   605.3444   406.0683   8.73E−01   −2.27E−1   1   Unchanged Low       Q04323   G01ef2   ORF   497.159   255   610.1121   454.2076   2.95E−01   −9.61E−01   1   Unchanged Low       P12004   G18ab8   proliferating cell nuclear antigen             332.1465   303   612.821   416.0883   8.84E−01   −1.31E−01   1   Unchanged Low       Q99720   M11cd6   sigma receptor (SR31747 binding   363.8609   379   615.0729   452.6158   7.57E−01   5.85E−02   1   Unchanged Low       P43307   G13cd2   signal sequence receptor; alpha   226.1566   322   618.9554   389.0352   1.45E+00   5.10E−01   1   Unchanged Low       Q9H3Y8   O05gh6   chromosome 20 open reading fra   221.2984   246   619.4944   362.4108   1.49E+00   1.55E−01   1   Unchanged Low       Q9NRX2   A08gh5   mitochondrial ribosomal protein              284.6282   305   827.9834   405.9846   1.14E+00   1.01E−01   1   Unchanged Low       Q9P2X0   L10gh2   dolichyl-phosphate mannosyltran   285.542   431   638.6696   451.8107   1.16E+00   5.95E−01   1   Unchanged Low       Q9Y5Z8   E05cd7   male-specific legthal 3-like 1 (Dro             361.7331   394   639.7431   465.0297   8.23E−01   1.22E−01   1   Unchanged Low       P78524   F01cd2   suppression of tumorigenicity 5   343.4117   289   643.333   425.1425   9.06E−01   −2.50E−01   1   Unchanged Low       P55145   F02ab2   arginine-rich; mutated in early st             413.1582   420   656.6324   496.4892   6.68E−01   2.26E−01   1   Unchanged Low       P33551   O23ab5   CDC28 protein kinase 1   296.3533   355   671.4891   440.861   1.18E+00   2.59E−01   1   Unchanged Low       Q9BVQ0   E09gh6   hypothetical protein MGC5363   43.30788   54.5   681.2449   259.6855   3.98E+00   3.32E−01   1   Unchanged Low       P34897   D15cd2   serine hydroxymethyltransferase   440.9652   290   685.6584   472.1838   6.37E−01   −6.05E−01   1   Unchanged Low       Q9Y5B4   L23ef2   androgen induced protein   268.4081   519   685.9395   491.1814   1.35E+00   9.52E−01   1   Unchanged Low       Q9Y2V5   B15ef2   transforming growth factor beta 1   249.1479   327   712.3879   429.636   1.52E+00   3.94E−01   1   Unchanged Low       Q13953   B19cd2   solute carrier family 12 (potassiu             342.5865   428   729.2688   499.9658   1.09E+00   3.21E−01   1   Unchanged Low       Q92686   I11ef6   neurogranin (protein kinase C su             330.8792   299   736.2348   455.4495   1.15E+00   −1.45E−01   1   Unchanged Low       O60565   J05cd8   cysteine knot superfamily 1; BMF   106.6904   151   781.0154   346.3594   2.87E+00   5.05E−01   1   Unchanged Low       Q9Y4M4   I21gh3   putative UDP-GalNAc:polypeptid             346.098   251   848.4309   481.2315   1.29E+00   −4.63E−01   1   Unchanged Low       P16581   E01ef7   selectin E (endothelial adhesion   109.3094   378   875.1666   454.0605   3.00E+00   1.79E+01   1   Unchanged Low       O14733   P02ef5   mitogen-activated protein kinase   98.83312   140   688.014   375.5944   3.17E+00   5.02E−01   1   Unchanged Low       Q16623   M24cd2   syntaxin 1A (brain)   403.2337   165   926.5022   498.3425   1.20E+00   −1.29E+00   1   Unchanged Low       Q9P1M5   P12gh3   WW domain containing oxidored   38.93   19.3   1292.23   450.1426   5.05E+00   −1.01E+00   2   Unchanged Medium       O60613   L18cd4   15 kDa selenoprotein   1220.902   1110   1285.07   1205.045   7.39E−02   −1.38E−01   2   Unchanged Medium       Q16698   M07ab4   2:4-dienoyl CoA reductase 1; mit   469.9997   706   615.3087   597.2594   3.89E−01   5.88E−01   2   Unchanged Medium       Q9HBA8   D23gh1   24-dihydrocholesterol reductase   768.0888   278   626.0195   557.2677   −2.95E−01   −1.47E+00   2   Unchanged Medium       Q9P012   M13ef4   30 kDa protein   546.352   691   614.5795   617.4113   1.70E−01   3.39E−01   2   Unchanged Medium       Q9UL53   P24cd7   5′-3′ exoribonuclease 2   648.132   604   430.2235   560.6322   −5.91E−01   −1.03E−01   2   Unchanged Medium       P49902   N16cd7   5′-nucleotidase; cytosollc II   1040.523   1220   440.0817   900.9404   −1.24E+00   2.32E−01   2   Unchanged Medium       O95336   P09cd7   6-phosphogluconolactonase   524.3104   755   812.5955   697.4428   6.32E−01   5.27E−01   2   Unchanged Medium       Q03393   A23ab8   6-pyruvoyltetrahydroptarin synth             358.0591   700   517.4335   525.0184   5.31E−01   9.66E−01   2   Unchanged Medium       Q13443   P01ef7   a disintegrin and metalloproteina   1306.754   481   445.3663   744.5037   −1.55E+00   −1.44E+00   2   Unchanged Medium       O75173   F15ab2   a disintegrin-like and metalloproteina   786.5151   1080   1254.804   1033.446   6.74E−01   4.29E−01   2   Unchanged Medium       P51572   O03gh1   accessory proteins BAP31/BAP2   985.1381   889   656.6554   843.6943   −5.85E−01   −1.48E−01   2   Unchanged Medium       P42765   D03ab2   acetyl-Coenzyme A acyltransfera   849.6041   1280   1204.131   1111.329   5.03E−01   5.92E−01   2   Unchanged Medium       P24666   E05ab2   acid phosphatase 1; soluble   1642.966   1970   1890.909   1833.204   2.03E−01   2.59E−01   2   Unchanged Medium       Q92688   D21cd6   acidic (leucine-rich) nuclear phos             470.8575   289   835.9103   531.9498   8.28E−01   −7.04E−01   2   Unchanged Medium       O14639   B21ab2   actin binding LIM protein   1351.973   393   358.779   701.2899   −1.91E+00   −1.78E−00   2   Unchanged Medium       O15143   F06ab2   actin related protein ⅔ complex   696.0033   513   349.0474   519.3549   −9.96E−01   −4.40E−01   2   Unchanged Medium       O15509   F12ab2   actin related protein ⅔ complex   909.0832   889   807.751   868.6913   −1.71E−01   −3.18E−02   2   Unchanged Medium       O15511   F14ab2   actin related protein ⅔ complex   732.1996   619   466.1372   605.8842   −6.51E−01   −2.42E−01   2   Unchanged Medium       P12718   A08ab6   actin; gamma 2; smooth muscle;   585.3438   846   2095.96   1175.856   1.84E+00   5.32E−01   2   Unchanged Medium       Q9P016   O09ef4   AD-015 protein   947.0386   837   1259.571   1041.448   4.11E−01   −1.79E−01   2   Unchanged Medium       O43747   M13ab2   adaptor-related protein complex   1104.332   532   419.4712   685.2957   −1.40E+00   −1.05E+00   2   Unchanged Medium       P20172   A11ab6   adaptor-related protein complex:   1266.83   1280   2285.193   1617.354   8.28E−01   −7.63E−03   2   Unchanged Medium       O14617   H07ab2   adaptor-related protein complex:   679.4847   495   357.0868   510.4994   −9.28E−01   −4.57E−01   2   Unchanged Medium       P07741   M24ab2   adenine phosphoribosyltransfera   1885.065   862   823.8455   1190.468   −1.19E+01   −1.13E−00   2   Unchanged Medium       P00568   A02ab2   adenylate kinase 1   2404.119   399   354.3768   1052.361   −2.76E+00   −2.59E+00   2   Unchanged Medium       Q9U1J7   I06ef2   adenylate kinase 3 alpha like   758.7288   1050   662.8834   828.3999   −1.95E−01   4.87E−01   2   Unchanged Medium       P30566   M07ab2   adenylosuccinate lyase   495.8874   622   518.4238   545.4304   5.90E−01   3.27E−01   2   Unchanged Medium       Q16186   M11cd7   adhesion regulating molecule 1   622.3901   610   574.5888   602.2578   −1.15E−01   −2.95E−02   2   Unchanged Medium       Q9NVF6   B19gh3   ADP-ribosylation factor 1 GTPas   449.3679   623   676.1878   582.9297   5.90E−01   4.72E−01   2   Unchanged Medium       P26438   B04ab2   ADP-ribosylation factor 6   732.1241   818   876.9277   809.1342   2.60E−01   1.61E−01   2   Unchanged Medium       P40616   D12ab2   ADP-ribosylation factor-like 1   827.1898   1220   1141.92   1064.016   4.65E−01   5.64E−01   2   Unchanged Medium       P36404   D14ab2   ADP-ribosylation factor-like 2   1751.048   1550   1871.661   1723.74   9.61E−02   −1.77E−01   2   Unchanged Medium       P56559   D20ab2   ADP-ribosylation factor-like 7   485.4562   598   568.6824   550.5764   2.28E−01   3.00E−01   2   Unchanged Medium       P35368   K17ab2   adrenergic; alpha-18: receptor   1433.715   1510   1335.995   1426.069   −1.02E−01   7.34E−02   2   Unchanged Medium       P15144   G24ab2   alanyl (membrane) aminopeptida   987.3343   222   480.1162   563.2289   −1.04E+00   −21.5E+00   2   Unchanged Medium       P30038   L09ab2   aldehyde dehydrogenase 4 famil             1179.797   598   657.4315   811.7082   −8.44E−01   −9.81E−01   2   Unchanged Medium       P14550   L05ab2   aldo-keto reductase family 1: m             555.464   886   609.9901   683.9189   1.35E−01   6.74E−01   2   Unchanged Medium       O43488   L07ab2   aldo-keto reductase family 7: m             546.409   525   748.5424   606.6855   4.54E−01   −5.74E−02   2   Unchanged Medium       P09972   C16ab2   aldolase C; fructose-bisphospha             878.5714   1050   947.5062   960.156   1.09E−01   2.63E−01   2   Unchanged Medium       O43590   G12ef4   alpha-actinin-2-associated LIM p   776.3757   1070   501.1993   783.883   −6.13E−01   4.68E−01   2   Unchanged Medium       Q08117   M19ab2   amio-terminal enhancer of split   1779.707   1430   1219.695   1476.318   −5.45E−01   −3.16E−01   2   Unchanged Medium       Q13438   G05cd7   amplified in osteosarcoma   658.0513   638   802.3407   699.6136   2.86E−01   −4.36E−02   2   Unchanged Medium       O96018   M01gh1   amyloid beta (A4) precursor proti             762.3898   750   1117.682   876.6611   5.52E−01   −2.38E−02   2   Unchanged Medium       Q13564   P11ab2   amyloid beta precursor protein bi   587.5144   664   786.6426   679.5497   4.21E−01   1.78E−01   2   Unchanged Medium       Q9Y679   B08cd7   ancient ubiquitous protein 1   1191.741   1270   1022.771   1160.442   −2.21E−01   8.81E−02   2   Unchanged Medium       Q9UKB4   B12ef2   anglomatin like 2   523.7253   776   568.8766   622.7291   1.19E−01   5.66E−01   2   Unchanged Medium       Q13725   H19ab2   anglotensin receptor 1   1495.332   1360   1058.942   1304.886   −4.98E−01   −1.36E−01   2   Unchanged Medium       P08133   I20ab2   annexin A6   253.0938   413   879.9474   515.5041   1.80E+00   7.08E−01   2   Unchanged Medium       P20073   I22ab2   annexin A7   650.1591   481   420.4945   517.0979   −6.29E−01   −4.36E−01   2   Unchanged Medium       P03971   E22ab2   anti-Mullerian hormone   1140.812   948   840.7158   909.9247   −8.32E−01   −2.67E−01   2   Unchanged Medium       P30041   O08cd5   anti-oxidant protein 2 (non-seleni   1248.922   1160   3067.945   1824.225   1.30E+00   −1.12E−01   2   Unchanged Medium       P27695   K06ef6   APEX nuclease (multifunctional              665.9854   653   835.6897   718.2149   3.27E−01   −2.85E−02   2   Unchanged Medium       Q9Y4J7   P01ab2   apoptosis inhibitor 5   1850.534   68.4   147.4186   688.7802   −3.65E+00   −4.76E+00   2   Unchanged Medium       Q9Y5L7   L03ef2   apoptosis related protein APR-3   662.9122   583   1426.489   890.7729   1.11E+00   −1.86E−01   2   Unchanged Medium       O94778   O14ab2   aquaporin 8   1475.036   1420   1474.307   1455.01   −7.13E−04   −5.92E−02   2   Unchanged Medium       O15296   E02ab2   arachidonate 15-lipoxygenase; s             826.8209   607   720.2105   718.1334   −1.99E−01   −4.45E−01   2   Unchanged Medium       P48444   O18ab2   archain 1   1291.871   1200   1374.223   1288.649   8.92E−02   −1.07E−01   2   Unchanged Medium       P00966   J24ab2   argininosuccinate synthetase   1049.688   1600   949.4889   1199.548   −1.45E−01   6.08E−01   2   Unchanged Medium       P42024   D15ab2   ARP1 actin-related protein 1 hon   1054.286   1720   1777.944   1518.804   7.54E−01   7.10E−01   2   Unchanged Medium       O43681   J16ab2   arsA arsenite transporter; ATP-bi   540.3448   724   595.3348   620.0089   1.40E−01   4.23E−01   2   Unchanged Medium       Q9ULX3   E02ef4   ART-4 protein   728.7274   595   509.3934   611.0757   −5.17E−01   −2.92E−01   2   Unchanged Medium       O96030   H16ab2   artemin   881.7849   728   638.2016   749.363   −4.66E−01   −2.76E−01   2   Unchanged Medium       P15289   F24ab2   arylsulfatase A   1639.546   1230   1012.121   1294.172   −6.96E−01   −4.14E−01   2   Unchanged Medium       P08243   J18ab2   asparagine synthetase   891.3027   643   1540.113   1024.719   7.89E−01   −4.72E−01   2   Unchanged Medium       O95630   L17ab2   associated molecule with the SH:   660.3522   872   729.2383   753.7548   1.43E−01   4.01E−01   2   Unchanged Medium       O95135   B09ab2   ataxin 2 related protein   902.4529   345   342.3299   530.0852   −1.40E+00   −1.39E+00   2   Unchanged Medium       O14530   N15ab2   ATP binding protein associated v   827.4646   1390   766.257   993.482   −1.11E−01   7.45E−01   2   Unchanged Medium       P30049   N20ab2   ATP synthase; H+ transporting; r   625.0408   468   441.4691   511.6658   −5.02E−01   −4.16E−01   2   Unchanged Medium       Q9UII2   I10ef2   ATPase inhibitor precursor   776.4612   1220   641.2787   878.5341   −2.76E−01   6.49E−01   2   Unchanged Medium       Q9Y5K8   F17ef2   ATPase; H+ transporting; lysoso             998.0597   1670   1029.886   1232.91   4.53E−02   7.43E−01   2   Unchanged Medium       O75787   P15ab2   ATPase; H+ transporting; lysoso             815.707   945   1081.688   947.5842   4.07E−01   2.13E−01   2   Unchanged Medium       P05023   P09ef5   ATPase; Na+/K+ transporting; al             1299.236   517   709.0882   841.8422   −8.74E−01   −1.33E+00   2   Unchanged Medium       P45844   P13ef5   ATP-binding cassette; sub-family   863.8068   381   606.1642   616.8957   −5.11E−01   −1.18E+00   2   Unchanged Medium       Q9HAP7   M08gh5   baculoviral IAP repeat-containing   1507.175   1740   1945.196   1730.54   3.68E−01   2.07E−01   2   Unchanged Medium       O94812   G09ab3   BAI1-associated protein 3   1073.67   983   826.6524   961.2437   −3.77E−01   −1.27E−01   2   Unchanged Medium       P35613   B14ef7   basigin (OK blood group)   603.4821   474   865.2409   647.414   5.20E−01   −3.50E−01   2   Unchanged Medium       Q9BSR6   A20gh8   BBP-like protein 1   816.219   1320   914.1927   1015.173   1.64E−01   6.88E−01   2   Unchanged Medium       O00512   K01ab3   B-cell CLL/lymphoma 9   1357.15   76.7   80.36541   504.741   −4.08E+00   −4.15E+00   2   Unchanged Medium       Q12983   E19ab5   BCL2/adenovirus E1B 19 kD inte             763.7046   548   991.4529   767.5569   3.77E−01   −4.80E−01   2   Unchanged Medium       Q92934   K24ef1   BCL2-antagonist of cell death   538.8191   727   603.5103   623.2249   1.64E−01   4.33E−01   2   Unchanged Medium       Q07817   E10ef8   BCL2-like 1   2062.673   2510   1097.372   1890.905   −9.10E−01   2.85E−01   2   Unchanged Medium       O43892   M23ab3   Bicaudal D homolog 1 (Drosophil   654.9397   414   548.7409   539.1375   −2.55E−01   −6.63E−01   2   Unchanged Medium       P53004   O19ab3   biliverdin reductase A   490.0724   569   512.2807   523.696   6.39E−02   2.15E−01   2   Unchanged Medium       O60629   G21ab3   bladder cancer associated protei             607.9847   1180   1083.411   956.1289   8.33E−01   9.53E−01   2   Unchanged Medium       Q9HBX3   N21gh6   brain and nasopharyngeal carcin   1672.876   54   44.02379   590.2997   −5.25E+00   −4.95E+00   2   Unchanged Medium       P56945   H23ef3   breast cancer anti-estrogen resis   1334.88   1300   1304.356   1312.13   −3.34E−02   −4.14E−02   2   Unchanged Medium       O15255   G21cd6   CAAX box 1   733.6878   577   1202.182   837.48   7.12E−01   −3.48E−01   2   Unchanged Medium       P12830   C16ef5   cadherin 1; type 1; E-cadherin (e   1094.64   924   489.5012   835.8959   −1.16E+00   −2.45E−01   2   Unchanged Medium       P19022   E03ef7   cadherin 2; type 1; N-cadherin (n   337.5528   540   747.1198   541.7151   1.15E+00   6.79E−01   2   Unchanged Medium       P22223   K19ef7   cadherin 3; type 1; P-cadherin (p   896.8467   1200   372.3054   823.6929   −1.27E+00   4.22E−01   2   Unchanged Medium       P22676   N07ab5   calbindin 2; (29 kD; calretinin)   1781.134   1500   2116.438   1797.589   2.49E−01   −2.52E−01   2   Unchanged Medium       Q99828   O19gh1   calcium and integrin binding 1 (c             1130.551   1320   838.3709   1096.979   −4.31E−01   2.26E−01   2   Unchanged Medium       P02593   I18ab4   calmodulin 1 (phosphorylase kin             1076.299   787   983.6302   949.1389   −1.30E−01   −4.51E−01   2   Unchanged Medium       Q13942   L01ab5   calmodulin 3 (phosphorylase kin             902.667   464   871.1455   746.0174   −5.13E−02   −9.59E−01   2   Unchanged Medium       P27824   I05ef1   calnexin   1492.644   1370   1543.709   1470.4   4.85E−02   −1.19E−01   2   Unchanged Medium       P17655   C20ef6   calpain 2; (m/ll) large subunit   671.5939   837   549.4365   685.847   −2.90E−01   3.17E−01   2   Unchanged Medium       P04632   C22ef6   calpain; small subunit 1   1565.935   1650   1258.047   1490.643   −3.16E−01   7.36E−02   2   Unchanged Medium       Q15417   P17ab5   calponin 3; acidic   911.495   603   737.1204   750.6841   −3.06E−01   −5.95E−01   2   Unchanged Medium       Q9UEG5   D17ef8   capicua homolog ( Drosophila )   629.0213   486   439.6052   518.1163   −5.17E−01   −3.73E−01   2   Unchanged Medium       P52907   O08ab4   capping protein (actin filament) n             848.0436   684   584.7035   705.5063   −5.36E−01   −3.11E−01   2   Unchanged Medium       Q9GZX3   N16gh1   carbohydrate (N-acetylglucosami   793.1054   929   751.3352   824.5253   −7.81E−02   2.28E−01   2   Unchanged Medium       Q16619   K01ab4   cardiotrophin 1   1478.249   1220   1559.477   1420.784   7.72E−02   −2.72E−01   2   Unchanged Medium       Q9UBD9   I24cd8   cardiotrophin-like cytokine; neur             361.4077   893   489.6592   581.3157   4.38E−01   1.30E+00   2   Unchanged Medium       Q15699   M16cd4   cartilage paired-class homeoprot   747.0317   596   1109.834   817.569   5.71E−01   −3.26E−01   2   Unchanged Medium       P48729   A22ab6   casein kinase 1; alpha 1   690.8551   1150   902.9474   914.9218   3.86E−01   7.36E−01   2   Unchanged Medium       P48730   L07ab4   casein kinase 1; delta   951.5238   1160   1111.571   1073.796   2.24E−01   2.84E−01   2   Unchanged Medium       P19138   L08ef5   casein kinase 2; alpha 1 polypep   483.6062   597   461.8036   513.9702   −6.66E−02   3.03E−01   2   Unchanged Medium       P49662   C12ef6   caspase 4; apoptosis-related cys   2013.957   2460   1017.425   1831.485   −9.85E−01   2.90E−01   2   Unchanged Medium       P21964   F19ef6   catechol-O-methyltransferase   697.5886   1170   1268.869   1046.831   8.63E−01   7.51E−01   2   Unchanged Medium       P26232   K01ef7   catenin (cadherin-associated pro   797.8639   717   810.257   774.9896   2.22E−02   −1.54E−01   2   Unchanged Medium       P35222   G07ef7   catenin (cadherin-associated pro   969.252   1290   1103.619   1121.277   1.87E−01   4.14E−01   2   Unchanged Medium       P07339   N23ef7   cathepsin D (lysosomal aspartyl              1253.01   947   1133.879   1111.314   −1.44E−01   −4.04E−01   2   Unchanged Medium       Q99967   C18cd6   Cbp/p300-interacting transactivar   1293.915   1600   2245.133   1711.366   7.95E−01   3.02E−01   2   Unchanged Medium       P49715   N17ef6   CCAAT/enhancer binding protein   882.9323   884   1045.45   937.3612   2.44E−01   1.26E−03   2   Unchanged Medium       P53567   N22ab5   CCAAT/enhancer binding protein   826.9569   1160   1584.869   1191.643   9.38E−01   4.92E−01   2   Unchanged Medium       O95627   B21cd8   CCR4-NOT transcription comple             606.4629   851   692.4535   716.7046   1.91E−01   4.89E−01   2   Unchanged Medium       Q04900   G02cd4   CD164 antigen; sialomucin   750.3086   570   673.7234   664.5986   −1.55E−01   −3.97E−01   2   Unchanged Medium       P07766   P07ab3   CD3E antigen; epsilon polypepti             1808.209   1410   2643.721   1953.844   5.48E−01   −3.59E−01   2   Unchanged Medium       P34810   A21ab4   CD68 antigen   2460.227   1100   1293.961   1617.586   −9.27E−01   −1.16E+00   2   Unchanged Medium       P18582   B21ab5   CD81 antigen (target of antiprolif   1303.144   938   1598.276   1279.761   2.95E−01   −4.75E−01   2   Unchanged Medium       Q16181   F09ef5   CDC10 cell division cycle 10 hon   426.6642   443   751.3623   540.3444   8.16E−01   5.42E−02   2   Unchanged Medium       Q16543   H01ef5   CDC37 cell division cycle 37 hon   1085.897   1050   1336.155   1158.574   2.99E−01   −4.35E−02   2   Unchanged Medium       O14735   I14cd6   CDP-diacylglycerol-inositol 3-ph   241.7793   1180   311.7422   579.4931   3.67E−01   2.29E+00   2   Unchanged Medium       P30260   F13ef5   cell division cycle 27   1060.812   1470   1469.824   1334.733   4.70E−01   4.74E−01   2   Unchanged Medium       P49427   B12ef7   cell division cycle 34   762.5808   1300   766.6843   942.0784   7.74E−03   7.66E−01   2   Unchanged Medium       P29373   F01ef7   cellular retinoic acid binding prot             1226.236   803   1350.177   1126.373   1.39E−01   −6.11E−01   2   Unchanged Medium       P41208   F09ab5   centrin; EF-hand protein; 2   539.1633   672   676.8582   629.3345   3.28E−01   3.18E−01   2   Unchanged Medium       O00522   F05ab4   cerebral cavemous malformation   870.4309   631   723.1482   741.4854   −2.67E−01   −4.64E−01   2   Unchanged Medium       O15183   B12cd3   CGG triplet repeat binding protei   402.949   610   883.3283   632.0808   1.13E+00   5.98E−01   2   Unchanged Medium       Q9Y2Z5   D07ef2   CGI-06 protein   721.6709   674   1177.641   857.6492   7.06E−01   −9.94E−02   2   Unchanged Medium       Q9Y3C3   J05ef2   CGI-120 protein   1229.537   1360   2124.304   1572.302   7.89E−01   1.49E−01   2   Unchanged Medium       Q9Y3D0   J11ef2   CGI-128 protein   1592.767   2370   2011.685   1992.502   3.37E−01   5.75E−01   2   Unchanged Medium       Q9Y3E5   J17ef2   CGI-147 protein   532.425   788   567.0634   629.3057   9.09E−02   5.66E−01   2   Unchanged Medium       Q9Y3E8   C08ef2   CGI-150 protein   785.276   924   778.0449   829.1206   −1.33E−02   2.35E−01   2   Unchanged Medium       Q9Y320   A19ef2   CGI-31 protein   745.0314   932   703.7829   793.4541   −8.22E−02   3.22E−01   2   Unchanged Medium       Q9Y357   P16ef1   CGI-40 protein   817.7272   769   418.6337   668.441   −9.66E−01   −8.87E−02   2   Unchanged Medium       Q9Y360   A10ef2   CGI-45 protein   786.0567   914   796.6229   832.2061   1.93E−02   2.17E−01   2   Unchanged Medium       Q9Y512   B04ef3   CGI-51 protein   967.3508   859   1045.638   957.4201   1.12E−01   −1.71E−01   2   Unchanged Medium       Q9Y390   K21ef2   CGI-81 protein   1391.902   802   1140.01   1111.152   −2.88E−01   −7.96E−01   2   Unchanged Medium       P40227   N20ab4   chaperonin containing TCP1; sut   1011.613   436   592.4944   679.9043   −7.72E−01   −1.22E+00   2   Unchanged Medium       Q99832   H07cd6   chaperonin containing TCP1; sut   1190.644   1090   1548.874f   1274.983   3.79E−01   −1.33E−01   2   Unchanged Medium       Q9UBR5   I23ef4   chemokine-like factor 1   1047.63   1800   1059.437   1303.992   1.62E−02   7.85E−01   2   Unchanged Medium       Q9UHN8   N05ef4   chemokine-like factor 1   1568.851   2030   1237.728   1611.343   −3.42E−01   3.70E−01   2   Unchanged Medium       P54105   L07ef5   chloride channel; nucleotide-sen:   471.0775   487   640.6855   532.9217   4.44E−01   4.80E−02   2   Unchanged Medium       Q14781   F09ef1   chromobox homolog 2(Pc class I   795.873   749   713.815   753.0305   −1.57E−01   −8.68E−02   2   Unchanged Medium       Q9BXS4   K12cd5   chromosome 1 open reading frar   874.0189   1370   904.3066   1050.603   4.91E−02   6.52E−01   2   Unchanged Medium       Q9NPA0   H07gh4   chromosome 11 hypothetical pro   998.8577   834   858.794   897.3389   −2.18E−01   −2.60E−01   2   Unchanged Medium       Q9UKR5   G14cd7   chromosome 14 open reading fra   1181.962   1160   1285.11   1207.747   1.21E−01   −3.18E−02   2   Unchanged Medium       P56378   M16cd5   chromosome 14 open reading fra   503.5233   690   890.9975   694.9486   8.23E−01   4.55E−01   2   Unchanged Medium       O95433   B22cd7   chromosome 14 open reading fra   656.1775   563   438.9755   552.8428   −5.80E−01   −2.20E−01   2   Unchanged Medium       Q9NV31   J23gh3   chromosome 15 open reading fra   853.8367   832   861.2221   848.9729   1.24E−02   −3.76E−02   2   Unchanged Medium       Q9NVE2   D09gh3   chromosome 2 open reading frar   648.49   671   468.6352   596.0999   −4.69E−01   4.96E−02   2   Unchanged Medium       Q9UI05   L04gh4   chromosome 20 open reading fra   2518.951   2140   1201.051   1952.881   −1.07E+00   −2.36E−01   2   Unchanged Medium       Q9P0A7   M09ef8   chromosome 20 open reading fra   581.9098   1080   1200.665   954.524   1.04E+00   8.93E−01   2   Unchanged Medium       Q9Y3B1   H22ef1   chromosome 20 open reading fra   1691.864   1230   783.7799   1235.108   −1.11E+00   −4.60E−01   2   Unchanged Medium       Q9BQ89   C01gh8   chromosome 20 open reading fra   1460.875   952   1221.732   1211.641   −2.58E−01   −6.17E−01   2   Unchanged Medium       Q96C58   J19gh7   chromosome 6 open reading frar   1254.647   1080   480.9999   940.0036   −1.38E+00   −2.10E−01   2   Unchanged Medium       Q9Y5Z4   K12ef3   chromosome 6 open reading frar   915.3818   988   372.3119   758.6366   −1.30E+00   1.10E−01   2   Unchanged Medium       Q00610   I12cd5   clathrin; heavy polypeptide (Hc)   1639.759   1210   1437.44   1427.503   −1.90E−01   −4.44E−01   2   Unchanged Medium       P56749   F04cd7   claudin 12   2262.278   2480   1233.472   1992.755   −8.75E−01   1.34E−01   2   Unchanged Medium       O43809   M15cd7   cleavage and polyadenylation sp   640.2301   503   683.3467   608.9825   9.40E−02   −3.47E−01   2   Unchanged Medium       O96005   G05ab4   cleft lip and palate associated tra   1353.338   1170   1394.845   1304.597   4.36E−02   −2.15E−01   2   Unchanged Medium       Q16740   E20cd4   ClpP caseinolytic protease; ATP-   625.8711   528   475.0848   543.0367   −3.98E−01   −2.45E−01   2   Unchanged Medium       P55085   O24ab5   coagulation factor II (thrombin) re   829.7537   979   392.7495   734   −1.08E+00   2.39E−01   2   Unchanged Medium       P13726   B05ab4   coagulation factor III (thrombopla   1079.841   880   442.6212   800.9723   −1.29E+00   −2.94E−01   2   Unchanged Medium       Q9Y678   D14ef8   coat protein gamma-cop   815.7993   738   1009.756   854.5161   3.08E−01   −1.45E−01   2   Unchanged Medium       Q15363   M11ef3   coated vesicle membrane protein   706.3054   804   870.2118   793.6589   3.01E−01   1.88E−01   2   Unchanged Medium       O43513   N06cd4   cofactor required for Sp1 transcri   591.8619   481   798.8706   623.9284   4.33E−01   −2.99E−01   2   Unchanged Medium       Q9Y281   N18cd8   cofilin 2 (muscle)   671.9394   270   1093.534   678.6369   7.03E−01   −1.31E+00   2   Unchanged Medium       P04141   G22gh6   colony stimulating factor 2 (gra             116.2139   1290   165.718   522.783   6.12E−01   3.47E+00   2   Unchanged Medium       P02745   L06ef1   complement component 1; q sub             683.4431   1650   798.2366   1042.465   2.24E−01   1.27E+00   2   Unchanged Medium       p29279   I16ab4   connective tissue growth factor   596.4123   537   1071.517   734.8489   8.45E−01   −1.52E−01   2   Unchanged Medium       O43191   B02cd3   COP9 constitutive photomorphog   855.8616   1030   1302.334   1062.925   6.06E−01   2.68E−01   2   Unchanged Medium       Q99627   C01cd7   COP9 homolog   788.2297   968   1195.497   984.0634   6.01E−01   2.97E−01   2   Unchanged Medium       O15387   G21cd7   COP9 subunit 6 (MOV34 homolo   590.9973   382   628.5041   533.8251   8.88E−02   −6.30E−01   2   Unchanged Medium       Q9ULV4   K18ef3   coronin; actin binding protein; 1C   1594.037   1200   1362.545   1385.839   −2.26E−01   −4.09E−01   2   Unchanged Medium       Q9BR76   I14gh7   coronin; actin-binding protein; 1E   708.5653   1080   690.8568   827.7864   −3.65E−02   6.13E−01   2   Unchanged Medium       Q41061   B22cd5   COX17 homolog; cytochrome c c   889.1581   1440   745.8658   1026.374   −2.54E−01   7.00E−01   2   Unchanged Medium       Q9Y6B2   E02ef8   CREBBP/EP300 inhibitory protei   946.9513   1030   1988.725   1323.308   1.07E+00   1.27E−01   2   Unchanged Medium       Q9NY68   C06gh4   CTL2 gene   1381.821   804   788.5002   991.4995   −8.09E−01   −7.81E−01   2   Unchanged Medium       P24385   O04ef5   cyclin D1 (PRAD1: parathyroid a             1214.611   2150   1100.478   1486.769   −1.42E−01   8.21E−01   2   Unchanged Medium       Q9NXT4   K09gh2   cyclin M2   1560.659   1720   1582.768   1620.99   2.03E−02   1.40E−01   2   Unchanged Medium       P01034   I11ab6   cystatin C (amyloid angiopathy a   1067.127   970   1366.396   1134.612   3.57E−01   −1.37E−01   2   Unchanged Medium       Q15828   I13ab4   cystatin E/M   967.1669   2790   451.3932   1404.267   −1.10E+00   1.53E+00   2   Unchanged Medium       P01036   C02ab6   cyctatin S   1261.605   466   1069.756   932.4892   −2.38E−01   −1.44E+00   2   Unchanged Medium       P52943   I05ab4   cysteine-rich protein 2   874.1939   499   1277.819   883.82   5.48E−01   −8.08E−01   2   Unchanged Medium       P13498   G18ab3   cytochrome b-245; alpha polyper   708.9954   1050   359.3156   707.7483   −9.81E−01   5.73E−01   2   Unchanged Medium       P00167   C04ab6   cytochrome b-5   2187.128   1480   1034.311   1565.893   −1.08E+00   −5.67E−01   2   Unchanged Medium       P00001   N24gh6   cytochrome c   547.6708   442   517.6125   502.4788   −8.14E−02   −3.09E−01   2   Unchanged Medium       P10606   I24gh6   cytochrome c oxidase subunit Vb   1364.01   2100   2087.456   1851.225   6.14E−01   6.24E−01   2   Unchanged Medium       P08574   P10ab5   cytochrome c-1   667.9346   443   441.6771   517.7383   −5.97E−01   −5.93E−01   2   Unchanged Medium       Q99426   C17gh1   cytoskeleton-associated protein   560.9411   684   777.3269   673.9633   4.71E−01   2.85E−01   2   Unchanged Medium       Q07065   G13cd7   cytoskeleton-associated protein   602.5101   575   1785.415   987.5887   1.57E+00   −6.78E−02   2   Unchanged Medium       Q15038   L13ef3   DAZ associated protein 2   808.0755   890   564.7611   754.4305   −5.17E−01   1.40E−01   2   Unchanged Medium       Q9H2L4   B18gh8   DC32   408.0427   702   780.2878   630.0414   9.35E−01   7.82E−01   2   Unchanged Medium       Q9NPA8   G22gh7   DC6 protein   944.3094   1570   1514.164   1342.189   6.81E−01   7.32E−01   2   Unchanged Medium       O60231   H13cd3   DEAD/H (Asp-Glu-Ala-Asp/His) t   753.8815   873   799.6561   808.7915   8.50E−02   2.11E−01   2   Unchanged Medium       Q9GZR7   E02gh4   DEAD/H (Asp-Glu-Ala-Asp/His) t   803.42   984   774.3765   854.0965   −5.31E−02   2.93E−01   2   Unchanged Medium       P17844   F04ab4   DEAD/H (Asp-Glu-Ala-Asp/His) t   1482.642   1440   1670.104   1530.749   1.72E−01   −4.26E−02   2   Unchanged Medium       Q08211   M03ab4   DEAD/H (Asp-Glu-Ala-Asp/His) t   907.5859   658   907.4343   824.2193   −2.41E−04   −4.65E−01   2   Unchanged Medium       Q9UJV9   D08ef2   DEAD-box protein abstrakt   976.8378   1230   870.3672   1024.437   −1.66E−01   3.28E−01   2   Unchanged Medium       P51398   G18ef6   death associated protein 3   920.3044   981   814.3518   905.1904   −1.76E−01   9.20E−02   2   Unchanged Medium       Q13437   G22cd4   Deleted in split-hand/split-foot 1             1565.344   1500   1721.872   1596.672   1.37E−01   −5.88E−02   2   Unchanged Medium       O60735   O06cd6   dendritic cell protein   858.6375   502   467.3432   609.2393   −8.78E−01   −7.75E−01   2   Unchanged Medium       Q16854   M06ab5   deoxyguanosine kinase   858.1918   885   989.3036   910.8082   2.05E−01   4.43E−02   2   Unchanged Medium       Q9Y295   H04ab8   developmentally regulated GTP I   736.3786   634   660.7023   676.9267   −1.56E−01   −2.17E−01   2   Unchanged Medium       P00387   F09ab3   diaphorase(NADH) (cytochrome   1402.134   1030   1435.74   1290.593   3.42E−02   −4.40E−01   2   Unchanged Medium       Q9UHY9   I08ef2   dicarbonyl/L-xylulose reductase   544.2125   740   938.7807   741.1   7.87E−01   4.44E−01   2   Unchanged Medium       P36957   C06ab6   dihydrolipoamide S-succinyltrans   625.9037   713   393.7165   577.6196   −6.69E−01   1.88E−01   2   Unchanged Medium       Q99075   M12ef7   diphtheria toxin receptor (heparir   721.8431   638   197.117   518.9525   −1.87E+00   −1.78E−01   2   Unchanged Medium       Q9UFN1   H10gh6   DKFZP564B147 protein   966.5927   947   1469.105   1127.658   6.04E−01   −2.91E−02   2   Unchanged Medium       O95882   C13ef8   DKFZP564C1940 protein   941.4076   865   804.639   870.3185   −2.26E−01   −1.22E−01   2   Unchanged Medium       Q9Y269   C07ef8   DKFZP564M082 protein   675.8991   1110   1208.543   998.4411   8.38E−01   7.17E−01   2   Unchanged Medium       Q9NWE3   J11ef8   DKFZP566C243 protein   419.5607   770   625.8483   605.084   5.77E−01   8.76E−01   2   Unchanged Medium       Q9H6Y7   H04gh6   DKFZP566H073 protein   1390.389   1480   1191.195   1352.292   −2.23E−01   8.55E−02   2   Unchanged Medium       Q9Y3X0   P23ef8   DKFZP586M1019 protein   588.3603   505   672.4872   588.5767   1.93E−01   −2.21E−01   2   Unchanged Medium       O60762   G19cd4   dolichyl-phosphate mannosyltran   407.0059   581   605.8353   531.3373   5.74E−01   5.14E−01   2   Unchanged Medium       P53805   B11ab5   Down syndrome critical region g             370.0907   663   511.9248   515.0794   4.68E−01   8.42E−01   2   Unchanged Medium       Q13597   N13ef3   downregulated in ovarian cancer   594.6931   693   623.702   636.966   6.87E−02   2.20E−01   2   Unchanged Medium       Q9C005   J05gh8   dpy-30-like protein   810.4585   1210   1174.001   1064.132   5.35E−01   5.76E−01   2   Unchanged Medium       Q13448   J03cd6   DR1-associated protein 1 (negati             1240.359   1140   2382.895   1586.247   9.42E−01   −1.27E−01   2   Unchanged Medium       Q9UHF9   K01ef4   dual oxidase 2   1146.14   648   316.6462   703.5318   −1.86E+00   −8.23E−01   2   Unchanged Medium       P61452   N22ab4   dual specificity phosphatase 3 (v             649.6813   605   473.5652   576.1845   −4.56E−01   −1.02E−01   2   Unchanged Medium       Q14203   A13ab6   dynactin 1 (p150; glued homolog   507.5942   529   623.6948   553.5576   2.97E−01   6.06E−02   2   Unchanged Medium       Q13561   D19cd6   dynactin 2 (p50)   1585.567   1380   1173.024   1372.261   −4.16E−01   −1.84E−01   2   Unchanged Medium       Q13409   I16ef1   dynein; cytoplasmic; intermediate   793.3207   604   464.9675   620.6506   −7.71E−01   −3.94E−1   2   Unchanged Medium       Q09472   C18ab4   E1A binding protein p300   1496.409   2120   1342.944   1651.644   −1.56E−01   5.00E−01   2   Unchanged Medium           D20gh8   EAF1 protein   642.1587   652   469.6834   588.0816   −4.51E−01   2.28E−02   2   Unchanged Medium       P78365   N19ab4   early development regulator 2 (p             894.3715   1070   761.5923   907.5945   −2.32E−01   2.54E−01   2   Unchanged Medium       Q99848   G11cd7   EBNA1 binding protein 2   977.8671   611   818.6583   802.3778   −2.56E−01   −6.79E−01   2   Unchanged Medium       Q12805   A21ab6   EGF-containing fibulin-like extra             1002.82   332   458.9563   597.7783   −1.13E+00   −1.60E+00   2   Unchanged Medium       Q9Y6I3   D21cd8   EH domain-binding mitotic phosp             736.8984   500   629.1845   621.9752   −2.28E−01   −5.60E−01   2   Unchanged Medium       Q15717   C04ab4   ELAV (embryonic lethal; abnorm             850.8493   800   843.4463   831.3485   −1.26E−02   −8.94E−02   2   Unchanged Medium       P13804   I24ab3   electron-transfer-flavoprotein; alp             916.8391   545   529.5868   664.3533   −7.96E−01   −7.54E−01   2   Unchanged Medium       Q14247   K17ef6   ems1 sequence (mammary tumo             1135.188   1050   1002.084   1063.9   −1.80E−01   −1.06E−01   2   Unchanged Medium       P42892   O21ab4   endothelin converting enzyme 1   602.4294   799   809.7071   737.1982   4.27E−01   4.08E−01   2   Unchanged Medium       P30084   A17ab6   enoyl Coenzyme A hydratase; sh   802.3114   1210   741.2226   917.9548   −1.14E−01   5.93E−01   2   Unchanged Medium       P07099   I20ab3   epoxide hydrolase 1; microsomal   1231.48   1840   1198.169   1424.661   −3.96E−02   5.83E−01   2   Unchanged Medium       P29692   H04ab5   eukaryotic translation elongation   1329.758   744   1110.87   1061.631   −2.59E−01   −8.37E−01   2   Unchanged Medium       P20042   L05cd4   eukaryotic translation initiation fa   1489.433   603   956.276   1016.24   −6.39E−01   −1.30E+00   2   Unchanged Medium       P41091   A20ab4   eukaryotic translation initiation fa   742.5843   474   478.7249   565.2535   −6.33E−01   −6.46E−01   2   Unchanged Medium       Q99613   L16cd3   eukaryotic translation initiation fa   1140.022   853   998.7488   997.2011   −1.91E−01   −4.19E−01   2   Unchanged Medium       P78344   C02ab4   eukaryotic translation initiation fa   1562.952   1520   1177.845   1419.665   −4.08E−01   −4.19E−02   2   Unchanged Medium       P23588   A24ab4   eukaryotic translation initiation fa   1343.019   1010   1125.825   1160.659   −2.54E−01   −4.07E−01   2   Unchanged Medium       Q13541   C03ab5   eukaryotic translation initiation fa   1655.926   1060   2293.236   1669.873   4.70E−01   −6.43E−01   2   Unchanged Medium       Q13542   A19ab6   eukaryotic translation initiation fa   1620.111   1850   1663.197   1712.605   3.79E−02   1.95E−01   2   Unchanged Medium       O60573   G16cd5   eukaryotic translation initiation fa   799.7789   883   819.3679   833.9147   3.49E−02   1.42E−01   2   Unchanged Medium       Q16394   K02ab3   exostoses (multiple) 1   513.7526   428   813.2693   584.9471   6.63E−01   −2.64E−01   2   Unchanged Medium       P37268   C17ab6   famesyl-diphosphate famesyltra             726.0862   455   649.0518   610.2023   −1.62E−01   −6.73E−01   2   Unchanged Medium       P55899   L22ab5   Fc fragment of IgG; receptor; tra             450.8629   771   476.1039   566.0193   7.86E−02   7.74E−01   2   Unchanged Medium       Q9UK73   P05ef3   fem-1 homolog b ( C. elegans )   548.2677   547   530.801   541.9489   −4.67E−02   −3.93E−03   2   Unchanged Medium       P21333   G14ab4   filamin A; alpha (actin binding pr             946.0465   675   1277.458   966.2982   4.33E−01   −4.86E−01   2   Unchanged Medium       P26885   P07ab4   FK506 binding protein 2 (13 kD)   814.6357   510   661.4593   662.0387   −3.01E−01   −6.76E−01   2   Unchanged Medium       Q13451   F15ab4   FK506 binding protein 5   1366.905   1110   812.8568   1097.248   −7.50E−01   −2.98E−01   2   Unchanged Medium       O95633   M01cd6   folllstatin-like 3 (secreted glycop             1312.174   1280   1092.99   1227.557   −2.64E−01   −3.86E−02   2   Unchanged Medium       P15407   A20cd4   FOS-like antigen 1   1696.135   1350   1218.491   1421.01   −4.77E−01   −3.31E−01   2   Unchanged Medium       Q14192   G02ab4   four and a half LIM domains 2   309.9219   591   1210.635   703.7424   1.97E+00   9.30E−01   2   Unchanged Medium       Q9NZA0   N17gh8   fuse-binding protein-interacting              924.2347   911   1110.468   981.791   2.65E−01   −2.13E−02   2   Unchanged Medium       P35637   P19ab4   fusion; derived from t(12; 16) mall             866.3996   654   1159.792   893.3381   4.21E−01   −4.06E−01   2   Unchanged Medium           E21gh7   FXYD domain-containing ion tra             942.6126   1060   802.8679   935.6666   −2.32E−01   1.71E−01   2   Unchanged Medium       Q9Y653   B02cd5   G protein-coupled receptor 56   2010.489   2160   1501.617   1889.081   −4.21E−01   1.00E−01   2   Unchanged Medium       Q9H1C0   E18gh4   G protein-coupled receptor 92   712.1007   750   719.7999   727.2869   1.55E−02   7.47E−02   2   Unchanged Medium       P15170   L13ab4   G1 to S phase transition 1   2042.425   1410   1109.721   1521.226   −8.80E−01   −5.33E−01   2   Unchanged Medium       O95166   D09cd7   GABA(A) receptor-associated pr             1280.495   2210   1227.378   1572.36   −6.11E−02   7.87E−01   2   Unchanged Medium       O08765   D21cd7   GABA(A) receptor-associated pr             1241.27   1130   918.8337   1095.839   −4.34E−01   −1.39E−01   2   Unchanged Medium       P16278   O05ef1   galactosidase; beta 1   539.4222   800   656.0518   665.3025   2.82E−01   5.69E−01   2   Unchanged Medium       P78537   J23ab4   GCN5 general control of amino-             813.3309   637   919.5196   790.0409   1.77E−01   −3.52E−01   2   Unchanged Medium       P31150   F14ab4   GDP dissociation inhibitor 1   633.6157   894   640.108   722.7008   1.47E−02   4.97E−01   2   Unchanged Medium       P08396   B23ab3   gelsolin (amyloidosis; Finnish typ             330.1567   577   633.2269   513.4286   9.40E−01   8.05E−01   2   Unchanged Medium       P52657   E03ab6   general transcription factor IIA; 2   538.6557   685   700.1857   641.1721   3.78E−01   3.46E−01   2   Unchanged Medium       Q00403   F08ef6   general transcription factor IIB   500.4565   791   454.8328   582.2035   −1.38E−01   6.61E−01   2   Unchanged Medium       P48060   I23cd7   glioma pathogenesis-related pro             676.4844   692   752.7928   707.2232   1.54E−01   3.35E−02   2   Unchanged Medium       P06744   B19ab3   glucose phosphate isomerase   900.9772   553   726.4749   726.7688   −3.11E−01   −7.05E−01   2   Unchanged Medium       P30101   G13ab5   glucose regulated protein; 58 kD   1708.658   1250   2220.105   1726.668   3.78E−01   −4.50E−01   2   Unchanged Medium       O43836   I22ef1   glutamate receptor; ionotropic; N   1729.777   1890   1655.131   1758.853   −6.36E−02   1.29E−01   2   Unchanged Medium       P15104   H22ab5   glutamate-ammonia ligase (gluta   1170.59   1040   1180.088   1130.151   1.17E−02   −1.71E−01   2   Unchanged Medium       Q06210   A23ab5   glutamine-fructose-6-phosphate              869.494   600   863.157   777.6585   −1.06E−02   −5.34E−01   2   Unchanged Medium       Q9Y3D4   M19ef2   glutaredoxin 2   888.5406   894   1099.209   960.4756   3.07E−01   8.32E−03   2   Unchanged Medium       Q9Y2Q3   C24ef2   glutathione S-transferase subunit   841.3959   346   414.7892   533.8957   −1.02E+00   −1.28E+00   2   Unchanged Medium       P48637   D01ab3   glultathione synthatase   650.8496   429   488.6663   522.9685   −4.13E−01   −6.00E−01   2   Unchanged Medium       P78417   E20cd5   glutathione-S-transferase like; g             1983.626   2020   1805.489   1937.888   −1.36E−01   2.95E−02   2   Unchanged Medium       P49840   J14ef4   glycogen synthase kinase 3 alph             1057.368   1460   1247.816   1254.087   2.39E−01   4.63E−01   2   Unchanged Medium       P13224   F23ab3   glycoprotein lb (platelet): beta pc   487.4684   530   653.4727   557.0977   4.23E−01   1.22E−01   2   Unchanged Medium       Q9UBQ7   L08cd7   glyoxylate reductase/hydroxypyn             947.0262   977   997.593   973.9926   7.50E−02   4.55E−02   2   Unchanged Medium       Q9P2T1   C02ef2   GMPR2 for guanosine monopho             762.0126   1070   817.0496   882.4154   1.01E−01   4.87E−01   2   Unchanged Medium       Q9H4A6   I04gh5   golgi phosphoprotein 3 (coat-pro   1027.603   1210   1209.783   1148.94   2.35E−01   2.35E−01   2   Unchanged Medium       P28789   B19ab5   granulin   1611.298   1750   1238.745   1532.188   −3.79E−01   1.16E−01   2   Unchanged Medium       Q14393   H10ab3   growth arrest-specific 6   484.489   563   739.1661   595.5619   6.09E−01   2.17E−01   2   Unchanged Medium       P29354   H06ef5   growth factor receptor-bound pro   721.5894   854   663.0587   746.3732   −1.22E−01   2.44E−01   2   Unchanged Medium       Q14451   D20ab4   growth factor receptor-bound pro   712.3296   846   636.8962   731.6029   −1.61E−01   2.47E−01   2   Unchanged Medium       Q9Y6G2   E04ef8   growth hormone inducible trans             1289.256   1020   974.263   1093.42   −4.04E−1   −3.43E−01   2   Unchanged Medium       P04899   J09ab4   guanine nucleolide binding prote             860.9208   1390   1748.649   1334.01   1.02E+00   6.94E−01   2   Unchanged Medium       P11016   M13ef5   guanine nucleotide binding prote             758.629   773   836.6295   789.4586   1.41E−01   2.73E−02   2   Unchanged Medium       Q13905   G09ab6   guanine nucleotide-releasing fac   410.0949   569   535.1889   504.61   3.84E−01   4.71E−01   2   Unchanged Medium       Q16774   L16ab3   guanylate kinase 1   968.5867   1340   975.8911   1095.967   1.08E−02   4.72E−01   2   Unchanged Medium       Q9Y649   K16ef4   GW128 protein   1663.305   2420   1834.174   1971.464   1.41E−01   5.39E−01   2   Unchanged Medium       P07305   G13ab5   H1 histone family; member 0   1780.353   1870   1746.555   1797.448   −2.77E−02   6.73E−02   2   Unchanged Medium       O75367   M14cd5   H2A histone family; member Y   1065.311   837   455.5967   786.0181   −1.23E+00   −3.48E−01   2   Unchanged Medium       P17317   C24ab6   H2A histone family; member Z   591.0013   461   1570.489   874.2269   1.41E+00   −3.58E−01   2   Unchanged Medium       P02278   M16gh6   H2B histone family; member G   586.8773   852   684.6287   707.973   2.22E−01   5.38E−01   2   Unchanged Medium       Q9NS37   A03gh5   HCF-binding transcription factor   857.3143   717   601.7268   725.1835   −5.11E−01   −2.59E−01   2   Unchanged Medium       O96004   E02cd5   heart and neural crest derivatives   705.5163   612   621.033   646.3401   −1.84E−01   −2.04E−01   2   Unchanged Medium       P10809   M11ef5   heat shock 60 kD protein 1 (chap             1693.23   1020   1276.41   1330.235   −4.08E−01   −7.30E−01   2   Unchanged Medium       P34932   I11ef1   heat shock 70 kD protein 4   1402.505   1610   1042.113   1352.283   −4.28E−01   2.01E−01   2   Unchanged Medium       P07900   G18ef7   heat shock 90 kD protein 1; alpha   2405.793   1430   1512.258   1783.374   −6.70E−01   −7.48E−01   2   Unchanged Medium       P08238   B20ab7   heat shock 90 kD protein 1; beta   2781.462   1950   979.1145   1903.993   −1.51E+00   −5.11E−01   2   Unchanged Medium       O75506   H17ab6   heat shock factor binding protein   1132.126   1300   1081.748   1171.256   −6.57E−02   1.99E−01   2   Unchanged Medium       Q9UHG4   K18ef4   heme-regulated initiation factor 2   413.2841   659   576.3971   549.5035   4.80E−01   6.73E−01   2   Unchanged Medium       P09105   J21ab4   hemoglobin; theta 1   702.445   484   769.2336   651.9692   1.31E−01   −5.37E−01   2   Unchanged Medium       O43504   D23cd6   hepatitis B virus x interacting pro   1008.655   1340   949.0116   1097.672   −8.79E−02   4.05E−01   2   Unchanged Medium       Q9H2I6   N10gh5   hepatitis C virus core-binding pro   676.7297   620   473.9328   590.1783   −5.14E−01   −1.27E−01   2   Unchanged Medium       P51858   K16ef7   hepatoma-derived growth factor              894.1008   1170   490.7458   850.7213   −8.65E−01   3.85E−01   2   Unchanged Medium       Q04150   A08ab7   heterogeneous nuclear ribonucle   943.3857   870   1065.597   959.787   1.76E−01   −1.16E−01   2   Unchanged Medium       Q13151   E15cd7   heterogeneous nuclear ribonucle   906.986   944   1143.552   998.1703   3.34E−01   5.77E−02   2   Unchanged Medium       P22626   N09ab6   heterogeneous nuclear ribonucle   1021.87   1010   1584.855   1206.298   6.33E−01   −1.38E−02   2   Unchanged Medium       P07910   A10ab7   heterogeneous nuclear ribonucle   747.5309   718   1059.349   841.6601   5.03E−01   −5.79E−02   2   Unchanged Medium       O14979   L09cd5   heterogeneous nuclear ribonucle   1057.699   1990   1646.172   1563.717   6.38E−01   9.10E−01   2   Unchanged Medium       P52597   G06ab7   heterogeneous nuclear ribonucle   1902.939   1280   1517.274   1567.536   −3.27E−01   −5.69E−01   2   Unchanged Medium       Q07244   N13ab6   heterogeneous nuclear ribonucle   847.6967   667   684.4978   733.1055   −3.09E−01   −3.46E−01   2   Unchanged Medium       Q15584   P03ab7   heterogeneous nuclear ribonucle   725.3651   569   858.2829   717.4409   2.43E−01   −3.51E−01   2   Unchanged Medium       P12081   J12ab4   histidyl-iRNA synthetase   555.5578   565   424.3904   514.8575   −3.89E−01   2.34E−02   2   Unchanged Medium       Q9UBN7   E11cd6   histone deacetylase 6   685.5336   407   695.1552   595.8457   2.01E−02   −7.53E−01   2   Unchanged Medium       Q13838   M07cd4   HLA-B associated transcript 1   681.4666   604   921.7532   735.5784   4.36E−01   −1.75E−01   2   Unchanged Medium       Q99873   H02ef7   HMT1 hnRNP methyltranferase-   890.1184   836   1209.872   978.6584   4.43E−01   −9.05E−02   2   Unchanged Medium       Q9H063   M14gh8   homolog of yeast MAF1   744.9951   921   1013.86   893.139   4.45E−01   3.05E−01   2   Unchanged Medium       P51610   L21ab5   host cell factor C1 (VP16-access   583.7478   580   735.1691   632.9786   3.33E−01   −9.25E−03   2   Unchanged Medium       O00165   I04cd6   HS1 binding protein   1482.068   1490   2425.818   1800.489   7.11E−01   1.12E−02   2   Unchanged Medium       Q9Y2Q5   P24ef7   HSPC003 protein   620.7783   1010   825.6574   752.165   1.13E−02   7.02E−01   2   Unchanged Medium       Q9Y2R0   A05ef8   HSPC009 protein   1507.005   1720   1784.568   1668.909   2.44E−01   1.87E−01   2   Unchanged Medium       Q9Y2T0   A17ef8   HSPC022 protein   453.0964   733   326.4215   504.1821   −4.73E−01   6.94E−01   2   Unchanged Medium       Q9UNZ5   C17ef8   HSPC023 protein   825.3888   1310   1347.488   1159.538   7.07E−01   6.62E−01   2   Unchanged Medium       Q9P032   O19ef8   HSPC125 protein   558.8905   602   843.0953   668.1435   5.93E−01   1.08E−01   2   Unchanged Medium       Q9P019   A06ef8   HSPC141 protein   717.9096   1700   1519.292   1312.254   1.08E+00   1.24E+00   2   Unchanged Medium       Q9P004   A24ef8   HSPC160 protein   1182.006   1070   545.8523   932.7666   −1.11E+00   −1.43E−01   2   Unchanged Medium       Q9P003   C04ef8   HSPC163 protein   801.5204   1410   1148.378   1118.827   5.19E−01   8.11E−01   2   Unchanged Medium       Q9P000   C06ef8   HSPC166 protein   508.2074   921   523.3806   650.7428   4.24E−02   8.57E−01   2   Unchanged Medium       Q9Y684   N09ef2   HSPCO34 protein   569.9533   628   797.4819   665.044   4.85E−01   1.39E−01   2   Unchanged Medium       Q9NRG2   D01gh4   HTGN29 protein   1276.132   1470   1639.451   1462.8   3.61E−01   2.07E−01   2   Unchanged Medium       Q16775   G15ab6   hydroxyacyl glutathione hydrolas   511.3412   676   407.0538   531.4885   −3.29E−01   4.03E−01   2   Unchanged Medium       P40939   D07ab3   hydroxacyl-Coenzyme A dehydr   1814.498   1770   1617.578   1733.575   −1.66E−01   −3.69E−02   2   Unchanged Medium       P55084   D09ab3   hydroxacyl-Coenzyme A dehydr   539.2691   890   1218.105   882.3271   1.18E+00   7.22E−01   2   Unchanged Medium       Q14526   B13ab5   hypermethylated in cancer 1   918.3678   904   1008.759   943.6552   1.35E−01   −2.30E−02   2   Unchanged Medium       Q9UBS2   A15ef1   hyperpolarization activated cyclic   676.9289   688   520.6835   628.6277   −3.79E−01   2.40E−02   2   Unchanged Medium       Q96EW8   P08gh8   hypothetical gene ZD52F10   727.4433   605   223.8014   518.5858   −1.70E+00   −2.67E−01   2   Unchanged Medium       Q9Y2S6   D01ef2   hypothtetical protein   1188.199   1490   1593.015   1423.596   4.23E−01   3.26E−01   2   Unchanged Medium       Q9UKZ1   I23gh3   hypothetical protein C40   657.2427   614   506.0272   592.3978   −3.77E−01   −9.84E−02   2   Unchanged Medium       Q9UJJ9   D21gh8   hypothetical protein CAB56184   432.491   695   601.25   576.3525   4.75E−01   6.85E−01   2   Unchanged Medium       O95891   D08ef8   hypothetical protein CL25022   1675.198   2070   1477.523   1741.841   −1.81E−01   3.07E−01   2   Unchanged Medium       Q9UJI9   F08gh6   hypothetical protein DJ328E19.C   1119.481   935   1005.691   1019.924   −1.55E−01   −2.60E−01   2   Unchanged Medium       Q9H0U3   K20gh8   hypothetical protein DKFZp564K   1287.049   1080   1145.302   1169.228   −1.68E−01   −2.59E−01   2   Unchanged Medium       Q9NWD8   N05gh2   hypothetical protein FLJ10099   754.9838   758   710.8818   741.1753   −8.68E−02   5.11E−03   2   Unchanged Medium       Q9NW90   P21gh2   hypothetical protein FLJ10211   492.5962   551   601.7235   548.3816   2.89E−01   1.61E−01   2   Unchanged Medium       Q9NW61   B18gh2   hypothetical protein FLJ10297   772.0358   844   620.8513   745.7235   −3.14E−01   1.29E−01   2   Unchanged Medium       Q9NW16   G04gh3   hypothetical protein FLJ10374   756.2846   543   467.9722   589.0741   −6.93E−01   −4.78E−01   2   Unchanged Medium       Q9NVZ3   G14gh3   hypothetical protein FLJ10420   437.615   702   362.923   500.7932   −2.70E−01   6.81E−01   2   Unchanged Medium       Q9NVC3   D23gh3   hypothetical protein FLJ10815   1402.842   928   598.595   976.6359   −1.23E+00   −5.95E−01   2   Unchanged Medium       Q9H9K7   B10gh5   hypothetical protein FLJ12681   446.1454   657   593.5606   565.6072   4.12E−01   5.59E−01   2   Unchanged Medium       Q9H8H4   H06gh5   hypothetical protein FLJ12800   1058.023   775   1421.894   1084.852   4.26E−01   −4.50E−01   2   Unchanged Medium       Q9P0R5   L02ef1   hypothetical protein FLJ14868   702.1841   684   1117.168   834.4521   6.70E−01   −3.78E−02   2   Unchanged Medium       Q9NXQ4   M07gh3   hypothetical protein FLJ20113   1503.987   1520   1545.141   1521.653   3.89E−02   1.13E−02   2   Unchanged Medium       Q9NXI2   M21gh3   hypothetical protein FLJ20234   643.4985   877   178.0291   566.3149   −1.85E+00   4.47E−01   2   Unchanged Medium       Q9NXD5   E18gh2   hypothetical protein FLJ20309   617.1482   1420   758.0334   932.5386   2.97E−01   1.20E+00   2   Unchanged Medium       Q9NX64   I16gh2   hypothetical protein FLJ20419   938.8958   825   981.6359   915.2399   6.42E−02   −1.86E−01   2   Unchanged Medium       Q9NWX1   A20gh3   hypothetical protein FLJ20552   1366.306   1800   1533.352   1565.249   1.66E−01   3.95E−01   2   Unchanged Medium       Q9NWT8   D11gh2   hypothetical protein FLJ20608   980.6383   915   907.2393   934.2965   −1.12E−01   −9.99E−02   2   Unchanged Medium       Q9NWM3   C20gh3   hypothetical protein FLJ20739   381.202   593   689.893   554.671   8.56E−01   6.37E−01   2   Unchanged Medium       Q9H7C7   D05gh5   hypothetical protein FLJ21044 si   551.5395   708   585.1487   615.0164   8.53E−02   3.61E−01   2   Unchanged Medium       Q9H6R6   J23gh5   hypothetical protein FLJ21952   425.3152   396   679.1125   500.0538   6.75E−01   −1.04E−01   2   Unchanged Medium       Q9H673   F11gh5   hypothetical protein FLJ22548 si   1394.825   1220   530.5646   1047.134   −1.39E+00   −1.98E−01   2   Unchanged Medium       O95476   H15efB   hypothetical protein HSA011916   1310.097   1040   1485.684   1279.962   1.81E−01   −3.27E−01   2   Unchanged Medium       Q9Y244   B23ef2   hypothetical protein HSPC014   1668.101   1530   1243.802   1481.658   −4.23E−01   −1.22E−01   2   Unchanged Medium       Q9P022   P04ef2   hypothetical protein HSPC138   666.1765   521   643.5979   610.0993   −4.97E−02   −3.56E−01   2   Unchanged Medium       Q9P013   P06ef2   hypothetical protein HSPC148   916.5214   1450   1133.279   1167.03   3.06E−01   6.63E−01   2   Unchanged Medium       Q9P009   P14ef2   hypothetical protein HSPC155   1031.658   1330   662.2481   1008.218   −6.40E−01   3.67E−01   2   Unchanged Medium       Q9P0S9   A19ef3   hypothetical protein HSPC194   1336.172   1570   1957.055   1622.151   5.51E−01   2.36E−01   2   Unchanged Medium       Q9NPI0   A23ef3   hypothetical protein HSPC196   280.0356   644   672.086   532.0086   1.26E+00   1.20E+00   2   Unchanged Medium       Q95887   C18ef2   hypothetical protein LOC51061   777.5591   709   551.8354   679.3596   −4.95E−01   −1.34E−01   2   Unchanged Medium       Q9P0T9   K02ef2   hypothetical protein LOC51234   1224.056   1290   1457.544   1322.295   2.52E−01   7.04E−02   2   Unchanged Medium       Q9P0Q1   K10ef2   hypothetical protein LOC51248   376.8259   933   1014.441   774.623   1.43E+00   1.31E+00   2   Unchanged Medium       Q9P0P0   K20ef2   hypothetical protein LOC51255   1301.286   2190   1904.375   1798.292   5.49E−01   7.50E−01   2   Unchanged Medium       Q9P0N9   K22ef2   hypothetical protein LOC51256   540.326   374   604.1319   506.0883   1.61E−01   −5.32E−01   2   Unchanged Medium       Q9NZD9   M23ef2   hypothetical protein LOC51323   600.1582   715   506.8479   607.2015   −2.44E−01   2.52E−01   2   Unchanged Medium       O75207   M02gh4   hypothetical protein LOC57019   663.8685   644   680.7704   663.0017   3.63E−02   −4.30E−02   2   Unchanged Medium       Q9BWL0   L24gh7   hypothetical protein MGC: 5244;   569.8856   436   732.9891   579.5932   3.63E−01   −3.87E−01   2   Unchanged Medium       Q9BW61   C09gh6   hypothetical protein MGC2594   1446.395   2460   1354.586   1754.667   −9.46E−02   7.68E−01   2   Unchanged Medium       Q9BQ49   K05gh6   hypothetical protein MGC2747   527.9287   679   677.2851   628.1009   3.59E−01   3.63E−01   2   Unchanged Medium       Q9BQD3   E17gh6   hypothetical protein MGC2479   841.5499   889   899.9017   876.8925   9.67E−02   7.95E−02   2   Unchanged Medium       Q9BQ61   A09gh6   hypothetical protein MGC2803   1234.395   2170   1980.421   1794.728   6.82E−01   8.13E−01   2   Unchanged Medium       Q9BTV4   O23gh6   hypothetical protein MGC3222   561.6572   502   583.5781   548.9637   5.52E−02   −1.63E−01   2   Unchanged Medium       Q9BVX2   C17gh6   hypothetical protein MGC5576   747.2479   762   604.3725   704.7101   −3.06E−01   2.91E−02   2   Unchanged Medium       Q9H773   I17gh6   hypothetical protein MGC5627   799.182   819   584.0079   734.1306   −4.53E−01   3.57E−02   2   Unchanged Medium       Q9BPX5   L02gh7   hypothetical protein similar aci   583.4076   424   632.4101   546.6359   1.16E−01   −4.60E−01   2   Unchanged Medium       Q9UJX8   B09ef3   hypothetical protein estradiol-inc   1184.334   948   1116.899   1083.179   −8.46E−02   −3.21E−01   2   Unchanged Medium       P00492   P12cd6   hypoxanthine phosphoribosyltrar   1210.895   233   566.0945   669.9473   −1.10E+00   −2.38E+00   2   Unchanged Medium       P22304   I04ab6   iduronate 2-sulfatase (Hunter syr   1197.3   1320   1095.895   1205.085   −1.28E−01   1.43E−01   2   Unchanged Medium       Q03827   F02ef6   immediate early protein   850.6538   537   536.2705   574.4895   −2.79E−01   −2.78E−01   2   Unchanged Medium       P12268   F11ab6   IMP (inosine monophosphate) de   1254.916   567   1293.693   1038.44   4.39E−02   −1.15E+00   2   Unchanged Medium       Q9Y6K9   P03cd3   inhibitor of kappa light polypeptic   822.3859   788   807.6888   805.9933   −2.60E−02   −6.78E−02   2   Unchanged Medium       Q14573   F04ab6   inositol 1;4;5-triphosphate recepl   555.9397   646   627.6143   609.9521   1.75E−01   2.17E−01   2   Unchanged Medium       O15357   L09ab6   inositol polyphosphate phosphat             997.7512   1150   1290.473   1146.828   3.71E−01   2.08E−01   2   Unchanged Medium       O15503   B05ab7   insulin induced gene 1   472.0202   428   615.7553   505.2037   3.84E−01   −1.42E−01   2   Unchanged Medium       P52945   L13gh8   insulin upstream factor 1   1437.285   3700   746.514   1961.135   −9.45E−01   1.36E+00   2   Unchanged Medium       P51460   B07ab7   insulin-like 3 (Leydig cell)   1227.459   1290   1040.851   1184.891   −2.38E−01   6.76E−02   2   Unchanged Medium       P46977   D20ab6   integral membrane protein 1   1693.474   1790   2514.977   1998.711   5.71E−01   7.81E−02   2   Unchanged Medium       Q13418   H08ef5   integrin-linked kinase   1340.442   962   1599.336   1300.502   2.55E−01   −4.79E−01   2   Unchanged Medium       P48551   O21ef7   interferon (alpha; beta and omeg   605.1613   669   389.178   554.33   −6.37E−01   1.44E−01   2   Unchanged Medium       P15260   A02ef7   interferon gamma receptor 1   1165.784   2600   1179.083   1648.504   1.64E−02   1.16E+00   2   Unchanged Medium       P38484   D12ef5   interferon gamma receptor 2 (Int             593.8133   773   550.2878   638.9669   −1.10E−01   3.80E−01   2   Unchanged Medium       O14896   K05ef6   interferon regulatory factor 6   495.9782   951   406.9438   617.9736   −2.85E−01   9.39E−01   2   Unchanged Medium           G13ef5   interferon-gamma receptor (IFNG   616.4461   474   457.8757   515.9592   −4.29E−01   −3.80E−01   2   Unchanged Medium       Q14116   L03ab6   interleukin 18 (Interferon-gamma   1525.444   1610   556.9614   1230.533   −1.45E+00   7.71E−02   2   Unchanged Medium       O75874   H11ab7   isocitrate dehydrogenase 1 (NA             660.9773   496   904.897   687.2716   4.53E−01   −4.14E−01   2   Unchanged Medium       P51553   I21gh1   isocitrate dehydrogenase 3 (NA             815.5318   899   784.1063   832.7908   −5.67E−02   1.40E−01   2   Unchanged Medium       P41252   P23ab6   isoleucine-IRNA synthetase   643.6728   316   992.267   650.6946   6.24E−01   −1.03E+00   2   Unchanged Medium       Q9UE89   J07ef7   jagged 2   657.9935   460   696.5019   604.7722   6.21E−01   −5.17E−01   2   Unchanged Medium       P52292   J14ab6   karyopherin alpha 2 (RAG cohor             1105.911   1270   1670.406   1350.126   5.95E−01   2.04E−01   2   Unchanged Medium       P24390   E07cd7   KDEL (Lys-Asp-Glu-Leu) endopl             1556.771   1210   1411.383   1392.342   −1.41E−01   −3.65E−01   2   Unchanged Medium       P08779   D03ab7   keratin 16 (focal non-epidermalyl   815.5106   786   663.0228   754.7055   −2.99E−01   −5.39E−02   2   Unchanged Medium       Q04695   O24ab6   keratin 17   580.3123   1180   1056.274   937.9159   8.64E−01   1.02E+00   2   Unchanged Medium       Q07666   B04cd6   KH domain containing: RNA bind   1212.816   780   1103.092   1031.926   −1.37E−01   −6.37E−01   2   Unchanged Medium       Q14165   O16gh1   KIAA0152 gene product   285.0232   348   1374.81   669.3755   2.27E+00   2.89E−01   2   Unchanged Medium       Q12765   F03gh1   KIAA0193 gene product   951.658   1000   981.6527   979.0013   4.48E−02   7.68E−02   2   Unchanged Medium       O43310   F11gh1   KIAA0427 gene product   482.1741   589   556.0999   542.3144   2.06E−01   2.88E−01   2   Unchanged Medium       O43167   J03gh1   KIAA0441 gene product   1398.244   982   1102.589   1160.899   −3.43E−01   −5.10E−01   2   Unchanged Medium       Q9H7D5   I18gh7   KIAA1191 protien   886.4026   1930   1061.302   1291.483   2.60E−01   1.12E+00   2   Unchanged Medium       Q9HD96   L03cd8   LAG1 longevity assurance homol   1319.272   798   1016.572   1044.592   −3.76E−01   −7.25E−01   2   Unchanged Medium       O00182   P04ab6   lectin; galactoside-binding: solub   760.6622   1300   527.6081   864.4149   −5.28E−01   7.79E−01   2   Unchanged Medium       Q99538   B04ef7   legumain   464.5   517   1105.037   695.3901   1.25E+00   1.53E−01   2   Unchanged Medium       O95751   G01cd8   leucine zipper; down-regulated ir   874.8344   274   970.9239   706.7407   1.50E−01   −1.67E+00   2   Unchanged Medium       O15468   P03ef4   leukocyte immunoglobulin-like re   828.8073   939   1120.204   962.0679   4.38E−01   1.84E−01   2   Unchanged Medium       Q9UBB4   I06cd8   like mouse brain protein E46   877.3997   623   692.5911   731.0054   −3.41E−01   −4.94E−01   2   Unchanged Medium       Q9UFW4   N17ef8   likely ortholog of rat golgi stackin   1680.361   1700   2121.05   1834.238   3.36E−01   1.79E−02   2   Unchanged Medium       Q14847   P09ab7   LIM and SH3 protein 1   664.6143   758   895.1972   772.769   4.30E−01   1.91E−01   2   Unchanged Medium       O00158   M09ef3   LIM domain only 4   457.4088   299   1353.355   703.0924   1.56E+00   −6.16E−01   2   Unchanged Medium       Q9HAP6   M16gh5   Lin-7b protein: likely ortholog of              2114.229   1550   2175.236   1945.862   4.10E−02   −4.50E−01   2   Unchanged Medium       P38571   K08ab6   lipase A; lysosmal acid; cholest,   604.0401   587   512.8879   568.1283   −2.36E−01   −4.02E−02   2   Unchanged Medium       Q99732   I18cd5   LPS-induced TNF-alpha factor   680.3876   893   449.4711   674.31   −5.98E−01   3.92E−01   2   Unchanged Medium       Q9Y4Z1   O21ef4   Lsm3 protein   1841.224   1300   1596.905   1511.517   −3.95E−02   −3.40E−01   2   Unchanged Medium       O75896   D05cd7   lung cancer candidate   690.6061   772   601.3296   688.0098   −2.00E−01   1.61E−01   2   Unchanged Medium       Q06843   O07ef6   lymphotoxin beta (TNF superfam   405.7368   1040   298.9254   582.7217   −4.41E−01   1.36E+00   2   Unchanged Medium       O95372   J04ef7   lysopholipase II   480.0562   737   752.7079   656.485   6.49E−01   6.18E−01   2   Unchanged Medium       P13473   N06ab6   lysosomal-associated membrane   952.6393   2000   1277.773   1408.92   4.24E−01   1.07E+00   2   Unchanged Medium       Q08397   F09ab7   lysyl oxidase-like 1   1391.453   1630   2243.025   1753.531   6.89E−01   2.25E−01   2   Unchanged Medium       Q15046   B17ab7   lysyl-tRNA synthetase   900.8177   556   539.813   665.5485   −7.39E−01   −6.96E−01   2   Unchanged Medium       Q13312   D17cd3   MAD1 mitotic arrest deficient-like   807.7627   503   574.4266   628.231   −4.92E−01   −6.85E−01   2   Unchanged Medium       Q09160   A05ab6   majar histocompatibility complex;   1524.076   2710   1290.783   1841.106   −2.40E−01   8.30E−01   2   Unchanged Medium       P40925   J23ab7   malate dehydrogenase 1; NAD (             1144.218   788   1089.134   1007.157   −7.12E−02   −5.38E−01   2   Unchanged Medium       P40926   L01ab7   malate dehydrogenase 2; NAD (             1525.837   1020   1212.544   1251.158   −3.32E−01   −5.88E−01   2   Unchanged Medium       Q16826   J15ef3   male-enhanced antigen   1253.21   1530   1827.301   1536.52   5.44E−01   2.87E−01   2   Unchanged Medium       Q9NQG1   C06gh5   mannosidase; beta A; lysosomal             533.2883   800   736.627   689.9075   4.66E−01   5.85E−01   2   Unchanged Medium       P26572   G11ab7   mannosyl (alpha-1;3-)-glycoprote   619.6733   369   887.6535   625.3732   5.18E−01   −7.49E−01   2   Unchanged Medium       Q10469   G15ab7   mannosyl (alpha-1:6-)glycoprote   600.1049   583   636.621   606.4146   8.52E−02   −4.29E−02   2   Unchanged Medium       P41223   L09cd4   maternal G10 transcript   372.2443   563   575.7695   503.5179   6.29E−01   5.96E−01   2   Unchanged Medium       Q9Y5V3   G13cd6   melanoma antigen: family D; 1   397.4495   952   1674.881   1008.268   2.08E+00   1.26E+00   2   Unchanged Medium       P43121   I22ef5   malanoma cell adhesion molecu             886.0756   795   432.1718   704.4837   −1.04E+00   −1.56E−01   2   Unchanged Medium       Q92494   D11ef1   membrane cofactor protein (CD4   973.362   1050   834.044   952.9144   −2.23E−01   1.11E−01   2   Unchanged Medium       Q14444   H15ab7   membrane component; chromos   549.4803   666   464.8174   560.0583   −2.41E−01   2.77E−01   2   Unchanged Medium       Q9NPE2   O12ef2   mesenchymal stem cell protein C   749.8938   932   1085.26   922.5469   5.33E−01   3.14E−01   2   Unchanged Medium       Q92571   G07ab7   mesoderm specific transcript hon   617.581   446   537.1735   533.4868   −2.01E−01   −4.71E−01   2   Unchanged Medium       O95204   N11ef3   metalloprotease 1 (pitrilysin fam             735.157   349   478.8153   520.899   −6.19E−01   −1.08E+00   2   Unchanged Medium       P80297   H20ab7   metallothionein 1L   589.6327   502   656.4441   582.747   1.55E−01   −2.32E−01   2   Unchanged Medium       Q99735   C18ef7   microsomal glutathione S-transfe   527.4698   686   373.9779   529.1741   −4.96E−01   3.79E−01   2   Unchanged Medium       Q98XW5   D13gh8   microtubule-associated protein 1   247.2817   692   887.6299   609.0447   1.84E+00   1.49E−00   2   Unchanged Medium       Q9Y6C9   M14ef3   mitochondrial carrier homolog 2   1874.893   1910   1893.062   1892.145   1.39E−02   2.56E−02   2   Unchanged Medium       Q9Y3B7   E07ef2   mitochondrial ribosomal protein 1   401.0368   421   732.113   517.9208   8.68E−01   6.88E−02   2   Unchanged Medium       Q9P015   A12ef8   mitochondrial ribosomal protein 1   553.658   760   589.0617   634.2498   8.94E−02   4.57E−01   2   Unchanged Medium       Q9NX20   M06gh2   mitochondrial ribosomal protein 1   642.9143   496   701.1442   613.4293   1.25E−01   −3.74E−01   2   Unchanged Medium       Q9H0U6   O13ef8   mitochondrial ribosomal protein 1   741.5383   1000   826.8816   856.3674   1.57E−01   4.32E−01   2   Unchanged Medium       Q9NZE8   O04ef2   mitochondrial ribosomal protein 1   914.9722   910   956.7888   927.2731   6.45E−02   −7.77E−03   2   Unchanged Medium       Q9P0P3   K18ef2   mitochondrial ribosomal protein 1   1217.101   891   1196.143   1101.306   −2.51E−02   −4.50E−01   2   Unchanged Medium       Q9Y317   M15ef2   mitochondrial ribosomal protein 1   799.6979   1020   1372.352   1063.499   7.79E−01   3.49E−01   2   Unchanged Medium       Q9Y6G3   C19ef8   mitochondrial ribosomal protein 1   571.7264   810   689.3229   690.2211   2.70E−01   5.02E−01   2   Unchanged Medium       Q9BYC7   K12gh8   mitochondrial ribosomal protein              490.5463   685   619.0928   591.6118   3.36E−01   4.39E−01   2   Unchanged Medium       Q9Y3D3   B12ef1   mitochondrial ribosomal protein              966.7611   1020   1006.958   997.1495   5.88E−02   7.41E−02   2   Unchanged Medium       Q9Y676   C15ef8   mitochondrial ribosomal protein              683.2889   580   761.9887   674.9976   1.57E−01   −2.37E−01   2   Unchanged Medium       Q9Y3D5   G19ef2   mitochondrial ribosomal protein              696.3306   1080   825.557   865.8021   2.46E−01   6.27E−01   2   Unchanged Medium       P82921   O11gh7   mitochondrial ribosomal protein              748.082   1190   1115.5   1019.33   5.76E−01   6.75E−01   2   Unchanged Medium       P82850   D07gh4   mitochondrial ribosomal protein              554.1784   515   470.683   513.1921   −2.36E−01   −1.07E−01   2   Unchanged Medium       Q9Y2Q9   A03ef8   mitochondrial ribosomal protein              1439.076   1420   1329.749   1395.534   −1.14E−01   −2.15E−02   2   Unchanged Medium       Q9NP92   F02ef3   mitochondrial ribosomal protein              669.1652   532   817.3223   606.105   −1.16E−01   −3.31E−01   2   Unchanged Medium       Q02750   J08ef5   mitogen-activated protein kinase   615.689   701   453.8702   590.1129   −4.40E−01   1.87E−01   2   Unchanged Medium       Q02779   K09ab7   mitogen-activated protein kinase   597.1743   423   509.6637   510.095   −2.29E−01   −4.96E−01   2   Unchanged Medium       Q12851   N10ab8   mitogen-activated protein kinase   988.0971   1020   976.7391   994.1804   −1.67E−02   4.26E−02   2   Unchanged Medium       P49137   J06ef5   mitogen-activated protein kinase   942.7459   1000   1068.579   1004.624   1.81E−01   8.87E−02   2   Unchanged Medium       Q9BYG3   O02gh8   MKI67 (FHA domain) Interacting   791.8688   407   307.4404   502.0002   −1.36E+00   −9.61E−01   2   Unchanged Medium       Q15014   C17cd8   MORF-related gene X   1146.48   1030   1262.273   1144.777   1.39E−01   −1.61E−01   2   Unchanged Medium           F22ef4   mRNA; clone: PO2ST9   1052.442   1040   905.2614   999.5166   −2.17E−01   −1.60E−02   2   Unchanged Medium       Q15773   M18ef5   myeloid leukemia factor 2   577.4585   467   766.6809   603.749   4.09E−01   −3.06E−01   2   Unchanged Medium       P35579   O01ef1   myosin; heavy polypeptide 9; no             1426.003   1150   1203.964   1261.007   −2.44E−01   −3.07E−01   2   Unchanged Medium       Q9Y6D2   C21ef2   N-acetyltransferase 5 (ARD1 ho             531.5485   708   274.9715   504.9319   −9.51E−01   4.14E−01   2   Unchanged Medium       P41227   G13gh1   N-acetyltransferase; homolog of   800.6676   905   818.2554   841.2057   3.13E−02   1.76E−01   2   Unchanged Medium       Q13510   H20ab2   N-acylsphingosine amidohydrola   752.1534   1680   677.5006   1028.456   −1.51E−01   1.14E+00   2   Unchanged Medium       O43678   O09ab7   NADH dehydrogenase (ubiquino             1366.754   1930   2137.906   1810.699   6.45E−01   4.96E−01   2   Unchanged Medium       O95167   E24ab7   NADH dehydrogenase (ubiquino             1431.655   1770   1506.934   1570.238   7.39E−02   3.08E−01   2   Unchanged Medium       P56556   O11ab7   NADH dehydrogenase (ubiquino             1650.612   916   795.8725   1120.973   −1.05E+00   −8.49E−01   2   Unchanged Medium       O95182   K06ab7   NADH dehydrogenase (ubiquino             750.0893   777   725.1711   750.6457   −4.87E−02   5.03E−02   2   Unchanged Medium       P51970   L04cd8   NADH dehydrogenase (ubiquino             554.1995   728   1021.163   767.6928   8.82E−01   3.93E−01   2   Unchanged Medium       O96000   J10ab8   NADH dehydrogenase (ubiquino             1110.197   1440   1111.615   1219.156   1.84E−03   3.71E−01   2   Unchanged Medium       O95178   J06ab8   NADH dehydrogenase (ubiquino             925.3926   768   815.266   836.3224   −1.83E−01   −2.68E−01   2   Unchanged Medium       O95139   M03ab8   NADH dehydrogenase (ubiquino             1392.873   1480   2182.279   1678.472   6.34E−01   8.78E−02   2   Unchanged Medium       P17568   H02ab8   NADH dehydrogenase (ubiquino             787.0681   587   591.1924   648.3703   −4.13E−01   −4.74E−01   2   Unchanged Medium       Q9Y6M9   P16ab8   NADH dehydrogenase (ubiquino             1299.803   1450   746.8017   1164.524   −7.99E−01   1.55E−01   2   Unchanged Medium       O43677   M05ab8   NADH dehydrogenase (ubiquino             586.5059   601   532.551   573.2205   −1.39E−01   3.43E−02   2   Unchanged Medium       O00217   M09ab8   NADH dehydrogenase (ubiquino             1383.411   1130   1194.001   1234.615   −2.12E−01   −2.96E−01   2   Unchanged Medium       P19404   M07ef1   NADH dehydrogenase (ubiquino             1151.224   443   356.308   650.0945   −1.69E+00   −1.38E+00   2   Unchanged Medium       O76008   A12cd6   Nef-associated factor 1   720.2744   951   424.04   698.4474   −7.64E−01   4.01E−01   2   Unchanged Medium       Q9UPY4   K22ef3   nesca protein   425.9149   469   621.9336   505.6782   5.46E−01   1.40E−01   2   Unchanged Medium           L19gh8   neurabin II   1241.544   862   1023.077   1042.081   −2.79E−01   −5.27E−01   2   Unchanged Medium       Q99742   O07ab8   neuronal PAS domain protein 1   1076.259   405   606.3589   695.8521   −8.28E−01   −1.41E+00   2   Unchanged Medium       O60448   P20ef3   neuronal thread protein   1831.592   1660   1490.624   1662.051   −2.97E−01   −1.38E−01   2   Unchanged Medium       Q9UNW9   O05ab8   neuro-oncological ventral antiger   1049.959   1050   1219.792   1106.982   2.16E−01   1.70E−03   2   Unchanged Medium       Q9UGL9   C09gh3   NICE-1 protein   1026.838   1360   381.058   923.3423   −1.43E+00   4.08E−01   2   Unchanged Medium       Q9UGL6   M09ef4   NICE-5 protein   912.7542   1390   955.016   1086.502   6.53E−02   6.09E−01   2   Unchanged Medium       Q92982   I09ef7   ninjurin 1   458.23   689   412.0181   519.6952   −1.53E−01   5.88E−01   2   Unchanged Medium       Q9BPW8   N19cd3   nipsnap homolog 1 ( C. elegans )   829.4266   529   562.9689   640.3075   −5.59E−01   −6.50E−01   2   Unchanged Medium       Q9NQR4   B13gh4   Nit protein 2   S19.1587   868   665.8632   684.4701   3.59E−01   7.42E−01   2   Unchanged Medium       Q9UF10   L08ef2   non-canonical ubquitin conjugati             1336.406   2000   1488.008   1608.811   1.55E−01   5.83E−01   2   Unchanged Medium       Q9Y385   H11ef2   non-canonical ubquitin conjugati             625.6356   808   669.812   701.1992   9.84E−02   3.69E−01   2   Unchanged Medium       Q15233   O02ef1   non-POU domain containing; oct.   1083.363   1210   1234.216   1174.503   1.88E−01   1.55E−01   2   Unchanged Medium       Q13137   A03cd6   nuclear domain 10 protein   910.7725   914   944.6079   923.1712   5.26E−02   5.31E−03   2   Unchanged Medium       Q16236   M03cd1   nuclear factor (erythroid-derived   1233.751   1180   1043.638   1153.088   −2.41E−01   −6.20E−02   2   Unchanged Medium       P08651   B07ef1   nuclear factor I/C (CCAAT-bindin   726.0476   624   659.6305   669.8575   −1.38E−01   −2.19E−01   2   Unchanged Medium       O95134   P10cd3   nuclear localization signal delete   465.2933   522   536.7333   508.0938   2.06E−01   1.67E−01   2   Unchanged Medium       Q15772   N19ab2   nuclear protein; marker for differ             1473.704   923   1157.202   1184.738   −3.49E−01   −6.75E−01   2   Unchanged Medium       Q9UHY1   L15cd8   nuclear receptor binding protein   515.949   948   619.7512   694.4539   2.64E−01   8.77E−01   2   Unchanged Medium       Q9UPC9   H23ab2   nuclear receptor coactivator 3   822.7768   1190   932.9058   982.77   1.81E−01   5.36E−01   2   Unchanged Medium       Q15325   N22cd2   nuclease sensitive element bind             1644.614   1720   2064.24   1808.771   3.28E−01   6.25E−02   2   Unchanged Medium       O00567   D05cd6   nucleolar protein 5A (56 kD with              659.4335   608   623.2536   630.2325   −8.14E−02   −1.17E−01   2   Unchanged Medium       Q9NX24   A10gh3   nucleolar protein family A; memb   466.2539   625   594.8443   581.9547   3.51E−01   4.22E−01   2   Unchanged Medium       P06748   K06gh6   nucleophosmin (nucleolar phosp             1605.368   1080   1136.972   1275.358   −4.98E−01   −5.67E−01   2   Unchanged Medium       P50583   B01ab2   nudlx (nucleoside diphosphate              1590.763   211   251.3768   684.354   −2.66E+00   −2.91E+00   2   Unchanged Medium       Q9UHM6   N20gh8   opsin 4 (malanopsin)   1076.73   1200   1643.887   1305.239   6.10E−01   1.50E−01   2   Unchanged Medium       Q9Y218   P22gh1   optinueurin   1014.697   1980   912.1917   1302.823   −1.54E−01   9.66E−01   2   Unchanged Medium       Q16612   O01cd5   P311 protein   322.7444   349   2231.846   967.7934   2.79E+00   1.12E−01   2   Unchanged Medium       P55771   J21cd7   paired box gene 9   692.506   380   573.135   548.4374   −2.73E−01   −8.67E−01   2   Unchanged Medium       Q9UKJ1   N21cd8   paired immunoglobulin-like rece             674.1862   450   558.3225   560.9087   −2.72E−01   −5.83E−01   2   Unchanged Medium       Q15165   P24ab7   paraoxonase 2   338.5244   891   583.7771   604.4337   7.86E−01   1.40E+00   2   Unchanged Medium       Q07002   P06ef5   PCTAIRE protein kinase 3   836.5659   916   632.7298   795.1858   −4.03E−01   1.31E−01   2   Unchanged Medium       Q9Y3C6   J07ef2   peptidylprolyl isomerase (cyclop             548.5938   731   526.6097   602.0621   −5.90E−02   4.14E−01   2   Unchanged Medium       P30405   F14cd5   peptidylprolyl isomerase F (cyclo   843.1834   925   467.6738   745.2396   −8.50E−01   1.33E−01   2   Unchanged Medium       O43924   G24ab8   phosphodiesterase 6D; cGMP-s             373.1208   630   699.1887   567.4949   9.06E−01   7.56E−01   2   Unchanged Medium       P17858   K10ab8   phosphofructokinase; liver   950.5746   525   774.727   750.1835   −2.95E−01   −8.56E−01   2   Unchanged Medium       Q01813   C17ef1   phosphofructokinase; platelet   573.5211   646   555.9236   591.6879   −4.50E−02   1.71E−01   2   Unchanged Medium       Q00511   N20cd3   phosphoprotein enriched in astrc   1330.005   1500   2288.098   1704.656   7.83E−01   1.70E−01   2   Unchanged Medium       P11216   B16ab8   phosphorylase; glycogen; brain   516.7884   495   988.163   666.5476   9.35E−01   −6.30E−02   2   Unchanged Medium       P00749   P19ef7   plasminogen activator; urokinase   1096.052   3440   1051.513   1861.568   −5.98E−02   1.65E+00   2   Unchanged Medium       P13797   C13cd1   plastin 3 (T isoform)   990.1173   804   1393.037   1062.438   4.93E−01   −3.00E−01   2   Unchanged Medium       Q15102   E16ab8   platelet-activating factor acetylhy   469.9778   674   468.9765   537.6672   −3.08E−03   5.20E−01   2   Unchanged Medium       P01127   A08ef5   platelet-derived growth factor bel   500.6466   674   456.4576   543.5869   −1.33E−01   4.28E−01   2   Unchanged Medium       Q15795   C19ef6   pleckstrin homology; Sec7 and              578.295   740   518.8327   612.22   −1.57E−01   3.55E−01   2   Unchanged Medium       O43660   O18ab8   pleiotropic regulator 1 (PRL 1hor             743.7263   933   804.3456   827.0995   1.13E−01   3.27E−01   2   Unchanged Medium       Q15155   G12ef3   pM5 protein   664.2511   423   490.295   525.8869   −4.38E−01   −6.51E−01   2   Unchanged Medium       Q9H361   L04gh7   poly(A) binding protein; cytoplas             759.4566   491   710.9543   653.8288   −9.52E−02   −8.29E−01   2   Unchanged Medium       Q15366   A11cd1   poly(rC) binding protein 2   1951.241   1490   2128.585   1857.745   1.26E−01   −3.86E−01   2   Unchanged Medium       P19388   B15ab8   polymerase (RNA) II (DNA direct   552.3545   529   698.4965   593.4201   3.39E−01   −6.12E−02   2   Unchanged Medium       P52434   F05gh6   polymerase (RNA) II (DNA direct   949.7064   1480   1210.411   1211.761   3.50E−01   6.35E−01   2   Unchanged Medium       P36954   A20cd1   polymerase (RNA) II (DNA direct   1603.557   1820   1413.573   1613.004   −1.82E−01   1.84E−01   2   Unchanged Medium       P53803   C17cd1   polymerase (RNA) II (DNA direct   437.9544   893   528.0144   619.6184   2.70E−01   1.03E+00   2   Unchanged Medium       Q9UQQ3   J08cd6   POP4 (processing of precursor;   480.5848   645   551.3661   558.9966   1.98E−01   4.25E−01   2   Unchanged Medium       Q13670   B07ab8   postmelotic segregation increase   812.7865   779   532.0548   708.0473   −6.11E−01   −6.07E−02   2   Unchanged Medium       Q9P0J7   L07gh4   potassium channel modulatory fa   1401.591   1720   1192.204   1438.482   −2.33E−01   2.97E−01   2   Unchanged Medium       O60925   K02ab8   prefoldin 1   1631.996   1720   1860.632   1737.289   1.89E−01   7.51E−02   2   Unchanged Medium       Q9UHV9   J15ef4   prefoldin 2   514.4897   882   833.1525   743.3158   6.95E−01   7.78E−01   2   Unchanged Medium       Q13519   J07ef6   prepronociceptin   564.2079   464   887.4522   638.4071   6.53E−01   −2.83E−01   2   Unchanged Medium       P04156   A13ab8   prion protein (p27-30) Creutzfel             797.9495   631   701.8217   710.1438   −1.85E−01   −3.39E−01   2   Unchanged Medium       Q9UI73   K03ef8   PRO0246 protein   430.412   535   546.8599   504.0018   3.45E−01   3.13E−01   2   Unchanged Medium       Q9P0T3   D14ef1   proapoptotic caspase adaptor p             1261.463   1650   2553.652   1820.221   1.02E+00   3.83E−01   2   Unchanged Medium       Q02809   P20ab7   procollagen-lysine; 2-oxoglutarat   503.7557   477   1993.232   991.2271   1.98E+00   −7.97E−02   2   Unchanged Medium       P07237   G13ab8   procollagen-proline; 2-oxoglutar             633.8309   406   575.6635   538.3489   −1.39E−01   −6.44E−01   2   Unchanged Medium       P09466   E12ab8   progestagen-associated endome   367.0939   625   708.8717   567.0247   9.49E−01   7.68E−01   2   Unchanged Medium       Q16342   G22ef6   programmed cell death 2   735.0961   759   490.3938   661.3332   −5.84E−01   4.52E−02   2   Unchanged Medium       O75340   I02cd8   programmed cell death 6   1055.888   1090   1358.597   1167.782   3.62E−01   4.70E−02   2   Unchanged Medium       P35232   C22ef5   porhibitin   2045.693   1810   1600.236   1818.121   −3.54E−01   −1.78E−01   2   Unchanged Medium       Q9UQ80   O03cd1   proliferation-associated 2G4; 38             1902.387   1390   2003.135   1763.59   7.44E−02   −4.58E−01   2   Unchanged Medium       Q12796   E05ab3   proline rich 2   1927.78   1530   1475.973   1643.691   −3.85E−01   −3.36E−01   2   Unchanged Medium       Q15188   P20cd2   proline-rich protein BstNI subfa             997.5582   1290   1404.4   1232.034   4.93E−01   3.76E−01   2   Unchanged Medium       P35998   L09ab8   proteasome (prosome; macropa             1010.463   1200   1059.594   1090.401   6.65E−02   2.49E−01   2   Unchanged Medium       P47210   N16cd2   proteasome (prosome; macropa             1037.339   1150   1193   1127.919   2.02E−01   1.53E−01   2   Unchanged Medium       O00495   N03ab8   proteasome (prosome; macropa             1043.875   498   563.7775   701.7628   −8.89E−01   −1.07E+00   2   Unchanged Medium       O75831   N07ab8   proteasome (prosome; macropa             763.7632   622   506.8297   630.7237   −5.92E−01   −2.97E−01   2   Unchanged Medium       Q13200   L15ab8   proteasome (prosome; macropa             644.3008   594   331.4288   523.3702   −9.59E−01   −1.16E−01   2   Unchanged Medium       O43242   L17ab8   proteasome (prosome; macropa             2159.327   1230   1637.67   1675.386   −3.99E−01   −8.13E−01   2   Unchanged Medium       P55036   N18cd2   proteasome (prosome; macropa             460.8093   724   588.5346   591.0419   3.53E−01   6.51E−01   2   Unchanged Medium       P48556   L21ab8   proteasome (prosome; macropa             1240.243   1030   1685.116   1317.42   4.42E−01   −2.72E−01   2   Unchanged Medium       Q92530   G07cd6   proteasome (prosome; macropa             1804.777   1570   1800.731   1724.253   −3.24E−03   −2.04E−01   2   Unchanged Medium       P28066   J13ab8   proteasome (prosome; macropa             766.589   767   775.2704   769.7417   1.62E−02   1.46E−03   2   Unchanged Medium       O14818   J15ab8   proteasome (prosome; macropa             1242.517   1540   1139.994   1308.162   −1.24E−01   3.12E−01   2   Unchanged Medium       P49721   J19ab8   proteasome (prosome; macropa             1832.921   2110   1617.062   1853.89   −1.81E−01   2.04E−01   2   Unchanged Medium       P28062   H18ab8   proteasome (prosome; macropa             797.3912   905   505.3638   735.864   −6.58E−01   1.82E−01   2   Unchanged Medium       P28065   B06ef7   proteasome (prosome; macropa             771.1998   1630   1002.72   1133.626   3.79E−01   1.08E+00   2   Unchanged Medium       P10619   A07ab8   protective protein for beta-galac             1539.157   907   980.3046   1142.279   −6.51E−01   −7.62E−01   2   Unchanged Medium       Q9UNN8   F03cd6   protein C receptor, endothelial (E   892.1589   702   488.5084   694.2014   −8.69E−01   −3.46E−01   2   Unchanged Medium       Q15084   H02cd5   protein disulfide isomerase-relat             1081.309   407   859.0228   782.4339   −3.32E−01   −1.41E+00   2   Unchanged Medium       Q9Y2B9   C22cd7   protein kinase (cAMP-dependent   650.9588   1040   754.6101   814.4047   2.13E−01   6.73E−01   2   Unchanged Medium       Q13517   A09ef5   protein kinase C binding protein   380.9448   587   630.5497   532.9442   7.27E−01   6.25E−01   2   Unchanged Medium       P54619   F15ab8   protein kinase; AMP-activated; g             482.8359   572   841.1746   632.0976   8.01E−01   2.45E−01   2   Unchanged Medium       P17612   F13ab8   protein kinase; cAMP-dependent   643.0385   629   901.5293   724.5168   4.87E−01   −3.19E−02   2   Unchanged Medium       P09131   F10gh1   Protein P3   529.0069   607   617.0621   584.2407   2.22E−01   1.98E−01   2   Unchanged Medium       O60927   P02gh1   protein phosphatase 1; regulator   1728.646   1760   1404.955   1630.486   −2.99E−01   2.42E−02   2   Unchanged Medium       P41236   C08cd1   protein phosphatase 1; regulator   532.1136   621   583.7663   576.9436   1.34E−01   2.23E−01   2   Unchanged Medium       Q15435   D15ab8   protein phosphatase 1; regulator   634.9759   963   753.9046   784.0242   2.48E−01   6.01E−01   2   Unchanged Medium       P05323   E13ef6   protein phosphatase 2 (formerly              1058.276   1120   796.6526   992.192   −4.10E−01   8.39E−02   2   Unchanged Medium       Q15257   G01ef5   protein phosphatase 2A; regulator   925.4458   905   1160.437   996.8116   3.26E−01   −3.29E−02   2   Unchanged Medium       P33172   F01ab8   protein phosphatase 4 (formerly              1791.171   1220   1064.665   1357.256   −7.51E−01   −5.59E−01   2   Unchanged Medium       O00743   F03ab8   protein phosphatase 6; catalytic              998.7   1070   738.4815   936.2693   −4.35E−01   1.02E−01   2   Unchanged Medium       P38391   E21cd7   protein translocation complex be             1049.306   1050   1428.451   1175.447   4.45E−01   −9.93E−04   2   Unchanged Medium       P78324   M17cd4   protein tyrosine phosphatase; no   639.2381   741   591.4877   657.1953   −1.12E−01   2.13E−01   2   Unchanged Medium       Q13332   P21ab8   protein tyrosine phosphatase; re             1882.284   1880   2019.865   1928.827   1.02E−01   1.57E−03   2   Unchanged Medium       Q9HAD6   C08gh6   protocadherin 16 dachsous-like (   987.2552   906   1070.494   981.1143   1.46E−01   −9.50E−02   2   Unchanged Medium       O43445   E11cd5   PRP4 pre-mRNA processing fact   777.1081   549   569.3749   631.8368   −4.49E−01   −5.01E−01   2   Unchanged Medium       Q9Y6B3   L19ef2   PTD013 protein   652.1251   701   1031.739   794.9108   6.62E−01   1.04E−01   2   Unchanged Medium       Q9HAN1   P19gh6   pumillo homolog 1 ( Drosophila )   842.4925   1170   1047.18   1019.233   3.14E−01   4.71E−01   2   Unchanged Medium       Q9NQA4   C23ef4   putative acid-sensing Ion channe   742.723   762   678.3813   727.7123   −1.31E−01   3.70E−02   2   Unchanged Medium       O43598   J05cd6   putative c-Myc-responsive   473.6498   621   459.383   517.9666   −4.41E−02   3.90E−01   2   Unchanged Medium       O43257   M12cd6   putative cyclin G1 interacting pro   1118.374   1190   1238.925   1183.655   1.48E−01   9.40E−02   2   Unchanged Medium       Q9NY06   M07ef4   putative integral membrane trans   966.4384   544   569.8565   693.4947   −7.62E−01   −8.29E−01   2   Unchanged Medium       P17152   H21cd4   putative receptor protein   399.9305   650   591.3162   547.029   5.64E−01   7.00E−01   2   Unchanged Medium       Q9Y6I9   B13ef2   putative secreted protein   373.307   485   742.537   533.7168   9.92E−01   3.79E−01   2   Unchanged Medium       P54886   B12ab8   pyrroline-5-carboxylate syntheta             406.7128   302   905.8993   538.0842   1.16E+00   −4.31E−01   2   Unchanged Medium       Q13876   B03ef7   quiescin Q6   745.299   585   842.2489   718.0657   1.45E−01   −3.50E−01   2   Unchanged Medium       O14679   K24ef5   quinone oxidoreductase homolo             710.5753   1160   651.2257   839.1208   −1.26E−01   7.02E−01   2   Unchanged Medium       P53611   N16ab8   Rab geranylgeranyltransferase; t   758.1496   727   938.6179   807.7755   3.08E−01   −8.14E−02   2   Unchanged Medium       P47224   D06ab8   RAB interacting factor   645.5902   859   577.3956   693.8748   −1.61E−01   4.11E−01   2   Unchanged Medium       Q15907   H04cd4   RAB11B; member RAS oncogen             926.8757   1030   1224.758   1060.693   4.02E−01   1.53E−01   2   Unchanged Medium       P51153   D04ab8   RAB13; member RAS oncogene   619.0867   935   1131.86   895.2783   8.70E−01   5.95E−01   2   Unchanged Medium       P35287   J24ef2   RAB14; member RAS oncogene   543.7425   584   586.1635   571.2023   1.08E−01   1.02E−01   2   Unchanged Medium       Q9NP72   P02ef8   RAB18; member RAS oncogene   459.4786   794   634.6616   629.3713   4.66E−01   7.89E−01   2   Unchanged Medium       P11476   H22ab8   RAB1A; member RAS oncogene   1039.455   767   993.588   933.4801   −6.51E−02   −4.38E−01   2   Unchanged Medium       Q9H0U4   L08gh7   RAB1B; member RAS oncogene   526.9882   691   696.5292   638.0939   4.02E−01   3.90E−01   2   Unchanged Medium       P08886   B22ab8   RAB2; member RAS oncogene f             1483.703   1900   2195.304   1858.384   5.65E−01   3.54E−01   2   Unchanged Medium       O95716   P04cd4   RAB3D; member RAS oncogene   908.9015   638   556.2242   701.181   −7.08E−01   −5.10E−01   2   Unchanged Medium       P35239   D02ab8   RAB5B; member RAS oncogene   598.5113   708   393.3892   566.5496   −6.05E−01   2.42E−01   2   Unchanged Medium       P20340   C07ef6   RAB6A; member RAS oncogene   503.1507   655   416.7552   524.9788   −2.72E−01   3.81E−01   2   Unchanged Medium       P43487   D16ab8   RAN binding protein 1   1438.305   1180   1786.177   1468.585   3.13E−01   −2.84E−01   2   Unchanged Medium       Q9UI26   B20ef1   Ran binding protein 11   1505.224   1180   1273.677   1319.368   −2.41E−01   −3.52E−01   2   Unchanged Medium       P47736   D18ab8   RAP1; GTPase activating protei             875.8692   414   461.3322   583.6391   −9.25E−01   −1.08E+00   2   Unchanged Medium       Q15382   F17cd2   Ras homolog enriched in brain 2   1435.587   2190   1635.792   1754.23   1.88E−01   6.10E−01   2   Unchanged Medium       P52199   B18ab2   ras homolog gene family; memb             534.6169   1520   399.0517   816.6152   −4.22E−01   1.50E+00   2   Unchanged Medium       P35238   B20ab2   ras homolog gene family; memb             1022.646   872   1019.472   971.4616   −4.48E−03   −2.29E−01   2   Unchanged Medium       Q14644   J08ef7   RAS p21 protein activator (GTPa   615.946   623   627.059   622.1475   2.58E−02   1.74E−02   2   Unchanged Medium       Q15404   A10cd8   Ras suppressor protein 1   1543.953   1920   2317.155   1925.544   5.86E−01   3.11E−01   2   Unchanged Medium       Q13283   H14cd5   Ras-GTPase-activating protein S   846.7267   789   571.1476   735.5498   −5.68E−01   −1.02E−01   2   Unchanged Medium       Q9NVQ9   M05gh1   Rec8p; a meiotic recombination              1334.371   1200   1325.85   1286.027   −9.24E−03   −1.56E−01   2   Unchanged Medium       O60895   K17cd6   receptor (calcitonin) activity modi   572.8174   519   899.2606   663.6562   6.51E−01   −1.43E−01   2   Unchanged Medium       P35244   I22ef6   replication protein A3 (14 kD)   544.0212   502   924.5385   656.7974   7.65E−01   −1.16E−01   2   Unchanged Medium       Q99623   D03cd7   repressor of estrogen receptor a             1139.283   689   1233.151   1020.486   1.14E−01   −7.25E−01   2   Unchanged Medium       Q9UMQ4   C01gh1   ret proto-oncogene (multiple end   769.2484   602   803.931   725.1999   6.36E−02   −3.53E−01   2   Unchanged Medium       Q9NQC3   M19cd7   reticulon 4   1459.586   586   927.9776   991.1835   −6.53E−01   −1.32E+00   2   Unchanged Medium       P47804   P03cd1   retinal G protein coupled recepto   403.1219   497   627.4176   509.1489   6.38E−01   3.02E−01   2   Unchanged Medium       Q16576   P07ef8   retinoblastoma binding protein 7   1539.006   1410   798.8744   1250.347   −9.46E−01   −1.23E−01   2   Unchanged Medium       O95357   D02cd4   retinoic acid induced 3   678.1926   713   206.6352   532.4837   −1.71E+00   7.14E−02   2   Unchanged Medium       Q15299   D20ef1   retinoic acid receptor-beta assoc   1060.232   979   1013.444   1017.603   −6.51E−02   −1.15E−01   2   Unchanged Medium       Q9UMY1   P05ef2   retinoic acid repressible protein   610.5279   726   588.2413   641.044   −5.86E−02   2.51E−01   2   Unchanged Medium       Q13017   M15ef6   Rho GTPase activating protein 5   560.443   807   514.6138   627.5049   −1.23E−01   5.27E−01   2   Unchanged Medium       O43182   B24ab2   Rho GTPase activating protein 6   1257.146   806   895.7191   988.3979   −4.89E−01   −6.41E−01   2   Unchanged Medium       O60274   F04gh6   Rho-specific guanine nucleotide   651.9484   577   366.4761   531.8448   −8.31E−01   −1.76E−01   2   Unchanged Medium       P07998   P21cd1   ribonuclease; RNase A family; 1   1294.476   3040   1592.811   1976.991   2.99E−01   1.23E+00   2   Unchanged Medium       P04843   B12cd1   ribophorin I   1493.814   1360   2248.214   1700.316   5.90E−01   −1.37E−01   2   Unchanged Medium       P04844   B14cd1   ribophorin II   1574.181   1170   1880.047   1540.461   2.56E−01   −4.32E−01   2   Unchanged Medium       P26373   D11cd1   ribosomal protein L13   2091.256   1200   1924.546   1739.922   −1.20E−01   −7.97E−01   2   Unchanged Medium       P40429   H12ef1   ribosomal protein L13a   1928.024   2060   1091.46   1694.794   −8.21E−01   9.89E−02   2   Unchanged Medium       P39019   J05cd1   ribosomal protein S19   1794.644   1480   2253.771   1841.785   3.29E−01   −2.81E−01   2   Unchanged Medium       P78317   B04cd1   ring finger protein 4   756.2395   661   668.8027   695.4611   −1.77E−01   −1.93E−01   2   Unchanged Medium       Q99942   F04cd2   ring finger protein 5   1016.837   949   1126.187   1030.595   1.47E−01   −1.00E−01   2   Unchanged Medium       O43148   A15cd4   RNA (guanine-7-) methyltransfer             572.6495   730   390.498   564.3647   −5.52E−01   3.50E−01   2   Unchanged Medium       O02916   F06ab8   RNA binding motif protein 4   533.7121   628   430.5298   530.87   −3.10E−01   2.36E−01   2   Unchanged Medium       Q9Y580   J10gh6   RNA binding motif protein 7   368.8423   710   558.043   545.5838   5.97E−01   9.45E−01   2   Unchanged Medium       Q14621   H07cd7   RNA binding protein (autoantige             499.5699   737   506.822   581.142   2.08E−02   5.61E−01   2   Unchanged Medium       Q93062   K17cd7   RNA binding protein gene with r             845.0994   659   640.4514   714.6837   −4.00E−01   −3.60E−01   2   Unchanged Medium       Q99497   B15cd7   RNA-binding protein regulatory s   1914.86   1400   2563.974   1958.111   4.21E−01   −4.56E−01   2   Unchanged Medium       Q99584   L17cd2   S100 calcium binding protein A1             492.6196   421   675.1457   529.713   4.55E−01   −2.25E−01   2   Unchanged Medium       P23526   A06ef1   S-adenosylhomocysteine hydorl             550.6181   603   478.692   544.258   −2.02E−01   1.32E−01   2   Unchanged Medium       O43865   H21ab2   S-adenosylhomocysteine hydorl             1460.581   526   466.4887   817.8431   −1.65E+00   −1.47E+00   2   Unchanged Medium       O14828   D02cd5   secretory carrier membrane prot             661.3976   460   481.9262   534.3923   −4.57E−01   −5.24E−01   2   Unchanged Medium       O75326   L05cd3   sema domain; immunoglobulin d             795.0564   768   943.1132   835.2276   2.46E−01   −5.09E−02   2   Unchanged Medium       O43278   I16cd2   serine protease inhibitor; Kunitz I   1295.263   1260   641.0775   1066.162   −1.01E+00   −3.74E−02   2   Unchanged Medium       O00271   C05ef5   serine protease inhibitor; Kunitz I   1379.545   1740   876.4128   1332.552   −6.55E−01   3.36E−01   2   Unchanged Medium       Q9UEW8   N22ef5   serine threonine kinase 39 (STE             1230.117   1030   841.1872   1032.185   −5.48E−01   −2.63E−01   2   Unchanged Medium       Q13043   P15cd2   serine/threonine kinase 4   750.7132   838   756.1662   781.5546   1.04E−02   1.58E−01   2   Unchanged Medium       Q9Y282   F01ef2   serologically defined breast canc   1279.414   1160   1907.544   1448.986   5.76E−01   −1.41E−01   2   Unchanged Medium       P35542   A02gh1   serum amyloid A4; constitutive   754.5041   1310   811.5701   959.3499   1.05E−01   7.98E−01   2   Unchanged Medium       O75790   I22cd6   seven transmembrane domain pr             761.3872   778   799.0998   779.5745   6.97E−02   3.16E−02   2   Unchanged Medium       Q9P0V3   H17ef3   SH3-domain binding protein 4   1204.005   1710   1539.363   1483.624   3.54E−01   5.04E−01   2   Unchanged Medium       Q99519   C13ab8   stalidase 1 (lysosomal stalidase)   712.4593   680   498.7449   630.4426   −5.15E−01   −6.70E−02   2   Unchanged Medium       Q92185   J20cd1   stalytransferase 8A (alpha-N-ac             622.4236   478   462.7941   520.9105   −4.28E−01   −3.82E−01   2   Unchanged Medium       Q9Y6A9   C05ef8   signal peptidase 12 kDa   449.125   742   887.4615   692.8575   9.83E−01   7.24E−01   2   Unchanged Medium       P21378   I04ef3   signal peptidase complex (18 kD)   630.5817   515   732.1592   626.0198   2.16E−01   −2.91E−01   2   Unchanged Medium       O15302   P10ab3   signal recognition particle 72 kD   1040.23   818   841.5078   899.9534   −3.06E−01   −3.47E−01   2   Unchanged Medium       O76094   J02cd2   signal recognition particle 72 kD   1473.56   965   1422.2   1286.822   −5.12E−02   −6.11E−01   2   Unchanged Medium       Q9UNL2   J10cd2   signal sequence receptor; gamm   1150.724   450   1654.744   1085.128   5.24E−01   −1.35E+00   2   Unchanged Medium       P40763   K09ef5   signal transducer and activator o   671.5038   545   348.0347   521.4351   −9.48E−01   −3.02E−01   2   Unchanged Medium       Q92783   M24cd3   signal transducing adaptor moie             827.9851   1020   725.7017   857.8322   −1.90E−01   3.01E−01   2   Unchanged Medium       Q9H723   N01gh5   similar to rat nuclear ubiquitous              749.7661   530   1258.65   846.2392   7.47E−01   −5.00E−01   2   Unchanged Medium       O15258   A04cd7   similar to  S. cerevisiae  RER1   710.8499   635   933.6382   759.8427   3.93E−01   −1.63E−01   2   Unchanged Medium       O14834   A11cd7   similar to  S. pombe  dim1+   701.2292   753   903.8926   786.0877   3.66E−01   1.03E−01   2   Unchanged Medium       O43617   H05ef3   similar to yeast BET3 (S. cerevis   1759.348   1750   1443.578   1650.871   −2.85E−01   −7.94E−03   2   Unchanged Medium       Q04837   G11cd2   single-standed DNA binding pro   1264.277   894   1034.75   1064.292   −2.89E−01   −5.00E−01   2   Unchanged Medium       P05455   E19gh1   sjogren syndrome antigen B (aut             850.9691   744   930.6428   841.9268   1.29E−01   −1.93E−01   2   Unchanged Medium       P43331   K08cd2   small nuclear ribonucleoprotein              916.3597   1260   1042.335   1073.82   1.86E−01   4.63E−01   2   Unchanged Medium       P09012   M12cd2   small nuclear ribonucleoprotein              546.0261   310   685.6636   514.5708   3.23E−01   −8.22E−01   2   Unchanged Medium       P08579   A03cd2   small nuclear ribonucleoprotein              502.6355   570   669.9879   581.0279   4.15E−01   1.83E−01   2   Unchanged Medium       P09234   A05cd2   small nuclear ribonucleoprotein              1054.327   1450   1302.742   1269.64   3.05E−01   4.62E−01   2   Unchanged Medium       P08578   A07cd2   small nuclear ribonucleoprotein              1901.214   1740   1818.557   1819.876   −6.41E−02   −1.28E−01   2   Unchanged Medium       Q15357   A11cd2   small nuclear ribonucleoprotein              382.4892   734   593.847   570.2015   6.35E−01   9.41E−01   2   Unchanged Medium       P14678   C23cd3   small nuclear ribonucleoprotein              2036.574   1280   1737.398   1686.175   −2.29E−01   −6.65E−01   2   Unchanged Medium       Q13487   P08cd1   small nuclear RNA activating co             517.5819   684   648.0121   616.6789   3.24E−01   4.03E−01   2   Unchanged Medium       P35326   E17cd3   small proline-rich protein 2A   290.6174   1030   839.3072   721.2318   1.53E+00   1.83E+00   2   Unchanged Medium       P55854   H04cd2   SMT3 suppressor of mif tow 3 ho   791.7437   658   962.4453   804.107   2.82E−01   −2.67E−01   2   Unchanged Medium       P14648   P19cd5   SNRPN upstream reading frame   1581.907   2270   1670.964   1839.36   7.90E−02   5.18E−01   2   Unchanged Medium       P55011   L17cd1   solute carrier family 12 (sodium             591.8676   740   517.2382   616.497   −1.94E−01   3.23E−01   2   Unchanged Medium       O95258   P15cd4   solute carrier family 25 (mitochor   476.3075   518   577.8319   523.9535   2.79E−01   1.20E−01   2   Unchanged Medium       O15431   A21ab5   solute carrier family 31 (copper t             1227.872   1010   1769.026   1336.855   5.27E−01   −2.77E−01   2   Unchanged Medium       P04920   L04cd1   solute carrier family 4; anion exc             1614.362   1560   1704.134   1624.765   7.81E−02   −5.33E−02   2   Unchanged Medium       Q01650   J11ef5   solute carrier family 7 (cationic a             832.6996   632   1032.106   832.1088   3.10E−01   −3.99E−01   2   Unchanged Medium       Q07890   H23cd2   son of sevenless homolog 2 (Dro   476.9505   568   680.8529   575.1528   5.14E−01   2.51E−01   2   Unchanged Medium       O60749   A19cd2   sorting nexin 2   364.9343   931   769.5782   688.5915   1.08E+00   1.35E+00   2   Unchanged Medium       O60493   A09cd4   sorting nexin 3   1008.916   1350   1180.469   1180.399   2.27E−01   4.22E−01   2   Unchanged Medium       Q9Y5X3   G06ef4   sorting nexin 5   676.0975   647   688.5568   670.591   2.63E−02   −6.32E−02   2   Unchanged Medium       Q01082   E09cd2   spectrin; beta; non-erythrocytic 1   571.4909   679   387.0403   545.8922   −5.62E−01   2.49E−01   2   Unchanged Medium       P52788   M10cd2   spermine synthase   895.1994   854   770.002   839.7693   −2.17E−01   −6.78E−02   2   Unchanged Medium       P17947   C19cd2   spleen focus forming virus (SFF             1307.418   1150   1646.278   1366.573   3.32E−01   −1.90E−01   2   Unchanged Medium       Q14818   D10ef6   splicing factor 1   547.0998   499   782.2929   609.3662   5.16E−01   −1.34E−01   2   Unchanged Medium       Q15427   K11cd6   splicing factor 3b; subunit 4; 49k             441.2394   612   540.0723   530.9445   2.92E−01   4.71E−01   2   Unchanged Medium       Q15815   M06cd2   splicing factor; arginine/serine-ri             738.2591   553   551.9082   614.261   −4.20E−01   −4.18E−01   2   Unchanged Medium       Q01130   H22cd1   splicing factor; arginine/serine-ri             553.5808   527   488.5465   522.9409   −1.80E−01   −7.18E−02   2   Unchanged Medium       P23152   H24cd1   splicing factor; arginine/serine-ri             1547.474   1460   1428.273   1480.13   −1.16E−01   −7.94E−02   2   Unchanged Medium       Q13503   L22cd4   SRB7 suppressor of RNA polym             712.8859   574   725.0591   670.5377   2.44E−02   −3.13E−01   2   Unchanged Medium       Q9P2R9   C23ef2   SRp25 nuclear protein   495.796   558   515.095   522.8318   5.51E−02   1.69E−01   2   Unchanged Medium       Q9H6I2   F07gh5   SRY (sex determining region Y)-             774.5162   970   714.8666   819.674   −1.16E−01   3.24E−01   2   Unchanged Medium       Q9BT81   I13gh8   SRY (sex determining region Y)-             497.0608   530   550.1706   525.7297   1.46E−01   9.25E−02   2   Unchanged Medium       O60526   M03cd6   STIP1 homology and U-Box cont             706.6078   538   543.7559   596.1019   −3.78E−01   −3.93E−01   2   Unchanged Medium       Q9Y6X1   A21ef4   stress-associated endoplasmic              1683.36   1220   2201.647   1700.636   3.87E−01   −4.68E−01   2   Unchanged Medium       P31948   M15ef3   stress-induced-phosphoprotein 1   438.1143   549   517.5834   500.9139   2.47E−01   3.32E−01   2   Unchanged Medium       P21912   E09gh1   succinate dehydrogenase compl             701.7228   902   751.7357   785.3111   9.93E−02   3.63E−01   2   Unchanged Medium       O14521   H04cd1   succinate dehydrogenase compl             628.8405   505   672.375   601.9355   9.66E−02   −3.18E−01   2   Unchanged Medium       P53597   I09gh1   succinate-CoA ligase; GDP-form             704.4006   491   553.293   582.7447   −3.48E−01   −5.22E−01   2   Unchanged Medium       O95605   P15cd5   SUMO-1 activating enzyme subu             776.4199   499   433.2742   569.4163   −8.42E−01   −6.39E−01   2   Unchanged Medium       Q16550   K01cd2   suppressor of Ty 4 homolog 1 (S   813.5735   1440   991.3588   1081.744   2.85E−01   8.24E−01   2   Unchanged Medium       Q15526   K07cd2   surfelt 1   468.3614   522   583.8097   524.7026   3.18E−01   1.56E−01   2   Unchanged Medium       O43539   P02cd1   SWI/SNF related; matrix associa             1047.14   1280   1212.614   1178.519   2.12E−01   2.85E−01   2   Unchanged Medium       Q9UPX1   D23cd7   synaptopodin   683.4973   536   421.1841   546.8885   −6.98E−01   −3.51E−01   2   Unchanged Medium       O95721   O09cd5   synaptosomal-associated protein   830.7721   1030   686.6755   849.1506   −2.75E−01   3.10E−01   2   Unchanged Medium       O43391   H09cd2   syndecan binding protein (synter   625.6962   640   379.1899   548.1569   −7.23E−01   3.17E−02   2   Unchanged Medium       Q15833   J04cd2   syntaxin binding protein 2   661.0175   556   840.6951   686.0183   3.47E−01   −2.49E−01   2   Unchanged Medium       Q92804   O20cd3   TAF15 RNA polymerase II; TAT             873.5584   605   1063.778   847.4936   2.84E−01   −5.30E−01   2   Unchanged Medium       Q9Y490   B04cd2   talin 1   1342.238   1170   2365.625   1625.187   8.18E−01   −2.01E−01   2   Unchanged Medium       O94797   H20ef7   Tara-like protein   899.0807   448   496.1404   614.3777   −8.58E−01   −1.01E+00   2   Unchanged Medium       Q13311   C05cd6   Tax1 (human T-cell leukemia vir             899.9979   1190   926.2314   1004.505   4.15E−02   4.00E−01   2   Unchanged Medium       Q16650   F08cd6   T-box; brain; 1   1407.309   1750   1777.889   1645.184   3.37E−01   3.15E−01   2   Unchanged Medium       P51864   O04ef7   teratocarcinoma-derived growth I   2037.212   1590   1447.46   1690.282   −4.93E−01   −3.61E−01   2   Unchanged Medium       P55061   O19cd2   testis enhanced gene transcript (   1540.968   1330   1972.323   1615.143   3.56E−01   −2.10E−01   2   Unchanged Medium       Q15569   P21cd2   testis-specific kinase 1   837.6269   796   708.1178   780.661   −2.42E−01   −7.31E−02   2   Unchanged Medium       O60636   F08cd5   tetraspan 2   468.1664   702   375.3225   515.2157   −3.19E−01   5.85E−01   2   Unchanged Medium       O60637   F06cd5   tetraspan 3   1025.362   742   545.9662   770.9441   −9.09E−01   −4.68E−01   2   Unchanged Medium       O95857   F13ef3   tetraspan NET-6 protein   702.1579   676   359.1921   578.9636   −9.67E−01   −5.58E−02   2   Unchanged Medium       Q99614   M03cd3   tetratricopeptide repeat domain 1   706.3536   891   635.5379   744.2616   −1.52E−01   3.35E−01   2   Unchanged Medium       Q13118   L05cd2   TGFB inducible early growth res             445.9691   601   679.2931   575.4732   6.07E−01   4.31E−01   2   Unchanged Medium       Q15583   A16cd2   TGFB-induced factor (TALE fami             885.9   1290   1140.439   1105.268   3.64E−01   5.42E−01   2   Unchanged Medium       Q9H3N1   N03gh7   thioredoxin domain-containing   409.6333   426   686.7997   507.428   7.46E−01   5.60E−02   2   Unchanged Medium       O43396   O17cd5   thioredoxin-like; 32 kD   1821.595   1710   1548.596   1693.179   −2.34E−01   −9.18E−02   2   Unchanged Medium       P04216   B02cd2   Thy-1 cell surface antigen   169.8064   298   4157.367   1541.609   4.61E+00   8.10E−01   2   Unchanged Medium       P12956   K10ef6   thyroid autoantigen 70 kD (Ku an             1172.56   1490   1395.803   1353.001   2.51E−01   3.46E−01   2   Unchanged Medium       P16035   P11ef7   tissue inhibitor of metalloprotein             360.2533   354   913.1351   542.4517   1.34E+00   −2.54E−02   2   Unchanged Medium       Q9H2X8   I08gh8   TLH29 protein precursor   710.2447   1000   1386.102   1033.648   9.65E−01   5.00E−01   2   Unchanged Medium       Q13077   L11cd2   TNF receptor-associated factor 1   1265.054   1270   756.401   1097.404   −7.42E−01   6.49E−03   2   Unchanged Medium       Q9NZ34   P08gh4   TPA regulated locus   1074.319   1090   1284.44   1148.575   2.58E−01   1.69E−02   2   Unchanged Medium       Q15369   D18ef6   transcription elongation factor B              771.5598   1100   693.1767   854.8396   −1.55E−01   5.11E−01   2   Unchanged Medium       Q15906   P11ef6   transcription factor-like 1   436.5561   510   878.9083   608.5936   1.01E+00   2.25E−01   2   Unchanged Medium       P50616   H08cd5   transducer of ERBB2; 1   888.8059   874   518.1816   760.3803   −7.78E−01   −2.40E−02   2   Unchanged Medium       Q13595   N04ef7   transformer-2 alpha (htra-2 alph             247.4437   612   698.379   519.219   1.50E+00   1.31E+00   2   Unchanged Medium       P37802   F05cd3   transgelin 2   1986.716   2240   1173.434   1798.473   −7.60E−01   1.70E−01   2   Unchanged Medium       Q9Y5Z9   D01cd8   transitional epithelia response pr             1324.284   875   1126.793   1108.824   −2.33E−01   −5.97E−01   2   Unchanged Medium       Q99595   K10cd6   translocase of inner mitochondri             450.6578   665   448.5161   521.2602   −6.87E−03   5.60E−01   2   Unchanged Medium       O60830   A09cd6   translocase of inner mitochondri             1646.564   1590   1992.925   1744.175   2.75E−01   −4.77E−02   2   Unchanged Medium       O14925   I24cd6   translocase of inner mitochondri             745.8102   813   653.4301   737.451   −1.91E−01   1.25E−01   2   Unchanged Medium       Q9Y5J9   E08cd8   translocase of inner mitochondri             1641.377   1550   1653.524   1615.991   1.06E−02   −7.98E−02   2   Unchanged Medium       Q15629   G18ef3   translocating chain-associating n             1003.031   1060   624.4499   897.0752   −6.84E−01   8.48E−02   2   Unchanged Medium       Q99442   C10cd2   translocation protein 1   526.8783   772   1065.397   788.001   1.02E+00   5.51E−01   2   Unchanged Medium       Q99805   A18cd5   transmembrane 9 superfamily m             1023.368   1260   957.2601   1081.028   −9.63E−02   3.03E−01   2   Unchanged Medium       Q9Y2B0   C20ef3   transmembrane protein 4   681.3857   1320   985.8397   995.6424   5.33E−01   9.54E−01   2   Unchanged Medium       P49755   J05ef4   transmembrane trafficking protei             1311.203   469   700.7243   827.066   −9.04E−01   −1.48E+00   2   Unchanged Medium           F03gh4   transmembrane; prostate androg   1287.98   841   662.4165   930.4505   −9.59E−01   −6.15E−01   2   Unchanged Medium       Q03519   B07cd1   transporter 2; ATP-binding casse             851.2148   573   680.8519   701.534   −3.22E−01   −5.72E−01   2   Unchanged Medium       Q9NWF9   P02gh2   TRIAD3 protein   665.9772   444   688.6646   599.4053   4.83E−02   −5.86E−01   2   Unchanged Medium       Q15656   O07ef7   TRK-fused gene   1878.254   1640   1858.307   1792.501   −1.54E−02   −1.95E−01   2   Unchanged Medium       Q92734   J17cd7   TRK-fused gene   1450.307   1810   1609.067   1624.429   1.50E−01   3.23E−01   2   Unchanged Medium       Q12815   A21ef7   trophinin associated protein (last   821.5601   1100   722.8644   879.96   −1.65E−01   4.15E−01   2   Unchanged Medium       P09493   O02cd1   tropomyosin 1 (alpha)   988.1694   429   1004.982   807.373   2.43E−02   −1.20E+00   2   Unchanged Medium       P49411   M11cd3   Tu translation elongation factor;              525.8572   555   476.4592   519.255   −1.42E−01   7.90E−02   2   Unchanged Medium       P05217   F03gh6   tubulin; beta; 2   1203.686   705   920.1831   942.8088   −3.87E−01   −7.73E−01   2   Unchanged Medium       P23258   K03cd3   tubulin; gamma 1   1733.971   1220   2149.365   1702.331   3.10E−01   −5.03E−01   2   Unchanged Medium       Q9UBN6   A16ef6   tumor necrosis factor receptor su   470.7412   751   531.524   584.4772   1.75E−01   6.74E−01   2   Unchanged Medium       Q13829   L22ef4   tumor necrosis factor; alpha-indu             849.276   792   552.7776   731.2933   −6.20E−01   −1.01E−01   2   Unchanged Medium       O00496   K21cd3   tumor suppressing subtransferab   628.3509   554   800.8751   661.0848   3.50E−01   −1.62E−01   2   Unchanged Medium       Q99816   G04cd4   tumor susceptibility gene 101   723.8133   766   627.1295   705.4904   −2.07E−01   8.08E−02   2   Unchanged Medium       P16422   C03ab7   tumor-associated calcium signal   1448.512   791   373.663   870.9367   −1.95E+00   −8.73E−01   2   Unchanged Medium       Q9NP84   K03ef2   type I transmembrane protein Fn   691.89   498   560.2824   583.2792   −3.04E−01   −4.75E−01   2   Unchanged Medium       Q9UJ47   O09cd8   type I transmembrane receptor (             792.9873   819   809.9056   807.3703   3.05E−02   4.69E−02   2   Unchanged Medium       P31946   K21ef6   tyrosine 3-monooxygenase/tryp             1220.989   955   724.9898   966.9847   −7.52E−01   −3.55E−01   2   Unchanged Medium       P35214   J19ef4   tyrosine 3-monooxygenase/tryp             881.0131   989   682.5327   850.9964   −3.68E−01   1.67E−01   2   Unchanged Medium       P27348   G15cd7   tyrosine 3-monooxygenase/tryp             2196.334   1540   1104.855   1615.078   −9.91E−01   −5.08E−01   2   Unchanged Medium       O60704   J01cd3   tyrosylprotein sulfotransferase 2   658.3761   299   686.1339   547.7036   5.96E−02   −1.14E+00   2   Unchanged Medium       Q9Y4Z0   G09cd8   U6 snRNA-associated Sm-like pr   837.5087   689   914.9547   813.8478   1.28E−01   −2.81E−01   2   Unchanged Medium       P14927   G06cd4   ubiquinol-cytochrome c reductas             995.1237   817   954.3085   922.1475   −6.04E−02   −2.85E−01   2   Unchanged Medium       Q9UI02   P18ef7   ubiquinol-cytochrome c reductas             953.6884   1460   1546.568   1320.75   6.97E−01   6.16E−01   2   Unchanged Medium       P31930   A22cd3   ubiquinol-cytochrome c reductas             846.6396   849   686.9864   794.0747   −3.01E−01   3.33E−03   2   Unchanged Medium       P22695   A24cd3   ubiquinol-cytochrome c reductas             468.5936   636   581.791   562.0633   3.12E−01   4.40E−01   2   Unchanged Medium       P07919   E08cd4   ubiquinol-cytochrome c reductas             1328.532   1810   1005.378   1382.391   −4.02E−01   4.49E−01   2   Unchanged Medium       P47985   E06cd4   ubiquinol-cytochrome c reductas             1519.763   1270   1127.575   1306.086   −4.31E−01   −2.58E−01   2   Unchanged Medium       Q9NZ09   N17ef1   ubiquitin associated protein   1588.177   1820   1392.592   1598.619   −1.90E−01   1.93E−01   2   Unchanged Medium       Q9UNP0   F09gh6   ubiquitin specific protease 15   525.3364   492   597.7817   538.3523   1.86E−01   −9.48E−02   2   Unchanged Medium       Q9UHP3   L21cd8   ubiquitin specific protease 25   554.0657   724   561.5817   613.0845   1.94E−02   3.85E−01   2   Unchanged Medium       P22314   O07cd3   ubiquitin-activating enzyme E1 (             1857.238   1640   1863.316   1788.503   4.71E−03   −1.75E−01   2   Unchanged Medium       Q13404   O23cd3   ubiquitin-conjugating enzyme E2   1073.414   1210   1128.962   1138.559   7.28E−02   1.77E−01   2   Unchanged Medium       P51669   D05cd4   ubiquitin-conjugating enzyme E2   1266.25   1300   1173.73   1247.427   −1.09E−01   4.05E−02   2   Unchanged Medium       P47986   O11cd3   ubiquitin-conjugating enzyme E2   616.3689   520   567.7317   567.8765   −1.19E−01   −2.47E−01   2   Unchanged Medium       O14933   H14cd4   ubiquitin-conjugating enzyme E2   717.4244   893   596.6415   735.6835   −2.66E−01   3.16E−01   2   Unchanged Medium       Q16781   D07cd4   ubiquitin-conjugating enzyme E2   923.6537   816   533.7389   757.984   −7.91E−01   −1.78E−01   2   Unchanged Medium       Q93068   A02cd3   ubiquitin-like 1 (sentrin)   1376.087   1530   1294.307   1399.48   −8.84E−02   1.51E−01   2   Unchanged Medium       Q15386   I10gh1   ubiquitin-protein isopeptide ligas             531.8659   630   628.2454   596.8686   2.40E−01   2.45E−01   2   Unchanged Medium       Q9UBK9   I15cd4   ubiquitously-expressed transcrip             936.2619   1060   1384.764   1125.743   5.65E−01   1.74E−01   2   Unchanged Medium       O60512   E11ab3   UDP-Gal:betaGlcNAc beta 1:4-             436.7634   610   542.39   529.5839   3.12E−01   4.81E−01   2   Unchanged Medium       P78383   P20cd5   UDP-galactose transporter relat             1570.135   1700   2180.117   1818.963   4.74E−01   1.15E−01   2   Unchanged Medium       Q16851   I24cd4   UDP-glucose pyrophosphorylase   1324.08   1260   1318.78   1302.468   −5.79E−03   −6.64E−02   2   Unchanged Medium       Q9NZ45   L02gh3   uncharacterized hematopoietic s             652.0685   670   696.5692   672.9895   9.52E−02   3.98E−02   2   Unchanged Medium       Q9NZ32   L20gh4   uncharacterized hypothalamus p   1035.575   1250   1354.231   1214.412   3.87E−01   2.75E−01   2   Unchanged Medium       Q9NZ29   L16gh4   uncharacterized hypothalamus p   659.53   992   1118.776   923.516   7.62E−01   5.89E−01   2   Unchanged Medium       Q15853   C02cd3   upstream transcription factor 2; c   601.6839   635   698.0128   644.9023   2.14E−01   7.78E−02   2   Unchanged Medium       Q92528   D02ef7   uridine monophosphate kinase   560.3976   685   623.5243   623.0076   1.54E−01   2.90E−01   2   Unchanged Medium       P15692   M04ef7   vascular endotheliai growth facto   460.9257   539   857.3853   619.202   8.95E−01   2.27E−01   2   Unchanged Medium       P50552   C08cd3   vasodilator-stimulated phosphop             468.4573   648   392.5569   502.9122   −2.55E−01   4.67E−01   2   Unchanged Medium       O60763   H16cd3   vesicle docking protein p115   639.538   543   745.4806   642.7624   2.21E−01   −2.35E−01   2   Unchanged Medium       Q15836   A15ef5   vesicle-associated membrane pn   804.2648   1370   1060.211   1076.578   3.99E−01   7.63E−01   2   Unchanged Medium       Q9UEU0   O22cd6   vesicle-associated soluble NSF              468.6024   697   698.3534   621.1953   5.76E−01   5.72E−01   2   Unchanged Medium       P14921   E24ef5   v-ets erythroblastosis virus E26              913.893   765   291.1538   656.6528   −1.65E+00   −2.57E−01   2   Unchanged Medium       P18206   C14cd3   vinculin   580.3315   857   865.7505   767.5496   5.77E−01   5.62E−01   2   Unchanged Medium       P00540   G08ef5   v-mos Moloney murine sarcoma   1115.145   728   663.6747   835.5051   −7.49E−01   −6.16E−01   2   Unchanged Medium       P01106   E18ef5   v-myc myelocytomatosis viral on             537.8131   601   405.1047   514.7639   −4.09E−01   1.61E−01   2   Unchanged Medium       P21796   C16cd3   voltage-dependent anion channe   483.8969   510   584.201   525.9036   2.72E−01   7.47E−02   2   Unchanged Medium       Q15765   C12cd3   von Hippel-Lindau binding prote             689.743   705   891.2621   762.0788   3.70E−01   3.20E−02   2   Unchanged Medium       P10398   D01ab4   v-raf murine sarcoma 3611 viral              1061.812   639   532.2153   744.4583   −9.96E−01   −7.32E−01   2   Unchanged Medium       P11233   A19ef6   v-ral simian leukemia viral oncog   848.7099   1060   1081.428   995.8044   3.50E−01   3.17E−01   2   Unchanged Medium       Q9Y6W5   A22gh1   WAS protein family; member 2   1283.077   1630   1493.145   1468.514   2.18E−01   3.45E−01   2   Unchanged Medium       Q9UPY6   L06cd6   WAS protein family; member 3   1503.584   1210   2151.643   1623.108   5.17E−01   −3.09E−01   2   Unchanged Medium       O75083   D15cd5   WD repeat domain 1   892.4425   977   983.3448   944.1492   1.10E−01   1.30E−01   2   Unchanged Medium       O76071   A24cd5   WD40 protein Clao1   609.8821   898   730.5311   746.1814   2.60E−01   5.58E−01   2   Unchanged Medium       Q9HCN4   H11gh6   XPA binding protein 1; putative              1199.21   1070   507.3277   923.9753   −1.24E+00   −1.71E−01   2   Unchanged Medium       Q9UM05   N17ef3   yeast Sec31p homolog   1887.447   1590   1542.778   1672.59   −2.91E−01   −2.50E−01   2   Unchanged Medium       Q9UQR1   P06gh1   zinc finger protein 148 (pHZ-52)   513.8639   737   563.7625   604.9201   1.34E−01   5.21E−01   2   Unchanged Medium       Q14119   G21ef5   zinc finger protein 161   1199.558   1760   1197.34   1387.253   −2.67E−03   5.57E−01   2   Unchanged Medium       Q9NW07   F06gh2   zinc finger protein 358   402.8342   575   684.7069   554.3431   7.65E−01   5.15E−01   2   Unchanged Medium       P20694   D04ef6   zinc finger protein 9 (a cellular re   1042.65   1010   856.5924   969.9823   −2.84E−01   −4.49E−02   2   Unchanged Medium