Abstract:
This sealed container ( 200 ) is provided with: a multi-chamber container ( 210 ) provided with eight containers ( 2100 ) arranged in an X direction; and an integral film ( 220 ) which seals openings ( 211 ) of all of the eight containers ( 2100 ). A tip ( 230 ) is accommodated in each of the containers ( 2100 ). The film ( 220 ) seals the openings ( 211 ) using sections including first folding lids and second folding lids which are capable of being folded towards sides of the containers ( 2100 ) by being pressed from an exterior. A sealed-container set ( 100 ) is configured by causing a plurality of the sealed containers ( 200 ) to engage with a support frame ( 300 ).

Description:
TECHNICAL FIELD 
       [0001]    The present invention relates to a sealed container and a sealed container set suitable for allowing a packaged substance housed in a clean condition to be taken out in a clean condition. 
       BACKGROUND ART 
       [0002]    In pharmaceutical tests, diagnoses, and treatments, it is important that instruments to be used and pharmaceuticals are not contaminated. For example, in such tests, liquid housed in a container in an endotoxin-free clean condition may be collected with a micropipette and used. 
         [0003]    As the above-mentioned container, for example, a liquid container illustrated in  FIGS. 1A and 1B  has been known. Liquid container  10  includes container body  12  provided with liquid supply part  11 , sealing sheet  14  disposed on frame  13  surrounding the opening of container body  12 , evaporation prevention sheet  15  disposed on sealing sheet  14 , and cover  17  that: is made of metal; has a plurality of through holes; and covers evaporation prevention sheet  15 . Evaporation prevention sheet  15  has a plurality of cross-shaped slits at positions corresponding to through holes  16 . Chip  20  of a micropipette is inserted from through hole  16  to press evaporation prevention sheet  15  to be bent by slit  18 , and reaches liquid housed in container body  12 . Thus, the liquid housed in container body  12  is collected into the micropipette (e.g., PTL 1). 
       CITATION LIST 
     Patent Literature 
       [0004]    PTL 1 
         [0005]    Japanese Patent Application Laid-Open No. 2007-263869 
       SUMMARY OF INVENTION 
     Technical Problem 
       [0006]    Evaporation prevention sheet  15  has slits  18 . Therefore, the inside of container body  12  is constantly in communication with the outside of liquid container  10  through slits  18 . Accordingly, the inside of container body  12  is contaminated from the outside of container body  12  through slits  18 , and as a result contaminated liquid may be collected. Thus, liquid container  10  has room for improvement in that a packaged substance housed in container body  12  in a clean condition is taken out from container body  12  in a clean condition. 
         [0007]    A first object of the present invention is to provide a sealed container which enables a packaged substance housed in a container in a clean condition to be taken out from the container in a clean condition. 
         [0008]    A second object of the present invention is to provide a sealed container set which is convenient for allowing the packaged substance to be taken out from the container in a clean condition. 
       Solution to Problem 
       [0009]    The present invention provides a sealed container including at least one container each having an opening, and a film adhered to the container to seal the opening, in which: the film includes a first film layer adhered to the container and a second film layer adhered to the first film layer; the first film layer has a first bendable lid part shaped by a first cut line at a portion corresponding to the opening, the first bendable lid part being bent toward the container when being pressed toward the container; the second film layer has a second bendable lid part shaped by a second cut line at a portion corresponding to the opening, the second bendable lid part being bent toward the container when being pressed toward the container; the first cut line and the second cut line do not overlap each other over the opening in a layered direction of the film; at least a part of the first bendable lid part and the second bendable lid part overlap each other in the layered direction; and both the second bendable lid part and the first bendable lid part are bent toward the container when the second bendable lid part is pressed toward the container. 
         [0010]    Further, the present invention provides a sealed container set including the sealed container including a multi-chamber container in which a plurality of the containers are arranged in one direction, and a support frame for supporting the sealed container. 
       Advantageous Effects of Invention 
       [0011]    In the sealed container according to the present invention, a two-layer structured film is pressed toward the container from the outside of the film to thereby form an opening which communicates between the inside and the outside of the container, and a packaged substance inside the container is extracted through the opening, thereby allowing the packaged substance to be taken out from the container while being in contact with a clean portion of the film. Thus, the present invention enables a packaged substance housed in a container in a clean condition to be taken out in a clean condition. The sealed container set according to the present invention can support a plurality of the containers. Thus, according to the present invention, it becomes possible to provide a sealed container set convenient for allowing the packaged substance to be taken out in a clean condition from the container. 
     
    
     
       BRIEF DESCRIPTION OF DRAWINGS 
         [0012]      FIG. 1A  is an exploded perspective view of a conventional liquid container, and  FIG. 1B  is a cross-sectional view schematically illustrating a structure of the liquid container when collecting liquid; 
           [0013]      FIG. 2  is a perspective view of a sealed container set according an embodiment of the present invention; 
           [0014]      FIG. 3A  is a plan view of the sealed container set according an embodiment of the present invention, and  FIG. 3B  is a cross-sectional view of the sealed container set taken along line B-B in  FIG. 3A ; 
           [0015]      FIG. 4  is a perspective view of a sealed container according an embodiment of the present invention; 
           [0016]      FIG. 5A  is a front view of the sealed container according to an embodiment of the present invention,  FIG. 5B  is a cross-sectional view of the sealed container taken along line B-B in  FIG. 3A , and  FIG. 5C  is a plan view of the sealed container; 
           [0017]      FIG. 6  is an enlarged view of portion C in  FIG. 5B ; 
           [0018]      FIGS. 7A, 7B, and 7C  are, respectively, a perspective view, a plan view, and a front view of a film according to an embodiment of the present invention; 
           [0019]      FIG. 8A  is an enlarged view of portion A in  FIG. 7B , and  FIG. 8B  is a cross-sectional view of the film according to an embodiment of the present invention taken along line B-B in  FIG. 8A ; 
           [0020]      FIG. 9A  is a cross-sectional view schematically illustrating the film and a pipetter, with a second bendable lid part being slightly pressed by the pipetter,  FIG. 9B  is a cross-sectional view schematically illustrating the film and the pipetter, with the second bendable lid part being further pressed by the pipetter,  FIG. 9C  is a cross-sectional view schematically illustrating the film, the pipetter and a chip, with the pipetter entering the container and being attached to the chip inside the container, and  FIG. 9D  is a cross-sectional view schematically illustrating the film, and the chip, with the chip that is attached to the pipetter being taken out from the container; 
           [0021]      FIG. 10A  illustrates a modification of an engaging part,  FIG. 10B  is an enlarged plan view of a main part of a modification of a support frame which engages with the engaging part, and  FIG. 10C  is an enlarged side view of a main part of a modification of the support frame; 
           [0022]      FIG. 11A ,  FIG. 11B , and  FIG. 11C  schematically illustrate, respectively, a first modification, a second modification, and a third modification of a first cut line and a second cut line in the present invention; 
           [0023]      FIG. 12A  and  FIG. 12B  schematically illustrate, respectively, a fourth modification and a fifth modification of a first cut line and a second cut line in the present invention; and 
           [0024]      FIG. 13  is an enlarged view of a main part of a modification of a sealed container according to the present invention. 
       
    
    
     DESCRIPTION OF EMBODIMENTS 
       [0025]    In the following, embodiments of the present invention will be described in detail with reference to the accompanying drawings. 
       Configuration 
       [0026]      FIG. 2  is a perspective view of sealed container set  100  according a first embodiment of the present invention.  FIG. 3A  is a plan view of sealed container set  100 , and  FIG. 3B  is a cross-sectional view of sealed container set  100  taken along line B-B in  FIG. 3A . Sealed container set  100  includes sealed container  200  and support frame  300 . 
         [0027]      FIG. 4  is a perspective view of sealed container  200 .  FIG. 5A  is a front view of sealed container  200 ,  FIG. 5B  is a cross-sectional view of sealed container  200  taken along line B-B in  FIG. 3A , and  FIG. 5C  is a plan view of sealed container  200 .  FIG. 6  is an enlarged view of portion C in  FIG. 5B . Sealed container  200  includes multi-chamber container  210  and film  220 . 
         [0028]    Multi-chamber container  210  includes eight containers  2100  arranged in a row in X direction ( FIG. 4 ). Containers  2100  each have opening  211  ( FIG. 5C ). In multi-chamber container  210 , containers  2100  are arranged such that openings  211  are arranged in a row in X direction. 
         [0029]    Each container  2100  is a slender bottomed container, with Z direction perpendicular to X direction being depth direction. Each container  2100  houses chip  230  for a micropipette ( FIG. 5B ). Chip  230  is, for example, housed in each container  2100  in an endotoxin-free clean condition. 
         [0030]    The shape of opening  211  can be set depending on the shape of a packaged substance housed in containers  2100 , and is a circular shape, for example, when the packaged substance is chip  230 . Multi-chamber container  210  further has protrusion  212  that protrudes toward film  220  in Z direction around opening  211  ( FIG. 6 ). The shape of protrusion  212  in a plan view is a circular shape which is the same as the shape of opening  211 . The protruded length of protrusion  212  in Z direction (h in  FIG. 6 ) is, for example, 0.5 mm. 
         [0031]    Multi-chamber container  210  further has breakable thin wall part  240  that connects containers  2100  which are adjacent to each other in X direction ( FIGS. 5A and 6 ). Thin wall part  240  is a part between outer peripheral walls of adjacent containers  2100 . 
         [0032]    The length of thin wall part  240  in Z direction is 5.0 mm, and the length (width) of thin wall part  240  in Y direction perpendicular to X and Z directions is 0.5 mm, and the length (thickness) of thin wall part  240  in X direction is 0.5 mm. 
         [0033]    Multi-chamber container  210  further has engaging parts  250  disposed at both ends of multi-chamber container  210  ( FIG. 4 ). Engaging part  250  has protruding part  251  that further protrudes outward from the end of multi-chamber container  210  along X direction, and rod  252  that extends in a direction opposite to film  220  from protruding part  251  along Z direction. 
         [0034]    Multi-chamber container  210  can be obtained, for example, by injection molding of resin. Examples of the resin include polyolefin resins, polyamide resins, polystyrene resins, methyl polymethacrylate resins, polycarbonates, and cycloolefin copolymer resins. Examples of the polyolefin resins include polypropylene resins such as homopolypropylene, random polypropylene, and block polypropylene; and polyethylene resins such as high-density polyethylene, and low-density polyethylene. Examples of the polyamide resins include nylon. Examples of the polystyrene resins include polystyrene in which a rubber component for reinforcement may be compounded. 
         [0035]      FIGS. 7A, 7B, and 7C  are, respectively, a perspective view, a plan view, and a front view of film  220 .  FIG. 8A  is an enlarged view of portion A in  FIG. 7B , and  FIG. 8B  is a cross-sectional view of film  220  taken along line B-B in  FIG. 8A . 
         [0036]    Film  220  has first film layer  221  adhered to multi-chamber container  210 , and second film layer  222  adhered to first film layer  221  ( FIGS. 6 and 7C ). 
         [0037]    First film layer  221  has first bendable lid part  225  shaped by first cut line  223  at a portion corresponding to each of openings  211 . Second film layer  222  has second bendable lid part  226  shaped by second cut line  224  at a portion corresponding to each of openings  211  ( FIGS. 8A and 8B ). 
         [0038]    As illustrated in  FIG. 5C and 8A , the shape of first cut line  223  is a curve convex toward one side in Y direction. Further, the shape of second cut line  224  is a curve convex toward the other side in Y direction. Z direction is a direction in which film  220  is layered. Y direction is a first direction perpendicular to Z direction. Note that X direction is a second direction crossing (in the present embodiment, perpendicular to) Y direction, and is also a direction in which openings  211  are arranged. 
         [0039]    First cut line  223  and second cut line  224  do not overlap in Z direction. Further, the positions of both ends of first cut line  223  in X direction are outside the positions of both ends of second cut line  224  ( FIG. 8A ). Further, all of the positions of both ends of first cut line  223  and the positions of both ends of second cut line  224  in X direction are inside opening  211  in X direction ( FIG. 5C ). 
         [0040]    Second bendable lid part  226  overlaps first bendable lid part  225  in Z direction ( FIG. 8A ). First bendable lid part  225  is a part, of first film layer  221 , which is bent toward container  2100  when being pressed toward container  2100 . Second bendable lid part  226  is a part, of second film layer  222 , which is bent toward container  2100  when being pressed toward container  2100 . For example, first bendable lid part  225  is a part, of first film layer  221 , sandwiched by first cut line  223  and second cut line  224  when viewed in a plan view. For example, second bendable lid part  226  is a part, of second film layer  222 , sandwiched by first cut line  223  and second cut line  224  when viewed in a plan view. Thus, film  220  is configured such that both second bendable lid part  226  and first bendable lid part  225  are bent toward container  2100  when second bendable lid part  226  is pressed toward container  2100 . 
         [0041]    Distance in X direction (Dx) from one end of first cut line  223  in X direction to one end of second cut line  224  in X direction ( FIG. 8A ) can be appropriately determined from such a range that: first cut line  223  and second cut line  224  do not overlap each other in Z direction; an opening of an intended size is formed when first bendable lid part  225  and second bendable lid part  226  are bent toward container  2100 ; and both first bendable lid part  225  and second bendable lid part  226  are bent toward container  2100  when second bendable lid part  226  is pressed toward container  2100 . For example, distance Dx is −2 to 2 mm when a case where the position of one end of second cut line  224  is closer to the edge of opening  211  than the position of one end of first cut line  223  is set as positive. 
         [0042]    Distance in Y direction (Dy) from one end of first cut line  223  in X direction to one end of second cut line  224  in X direction ( FIG. 8A ) can be appropriately determined from such a range that: first cut line  223  and second cut line  224  do not overlap each other in Z direction; and both first bendable lid part  225  and second bendable lid part  226  are bent toward container  2100  when second bendable lid part  226  is pressed toward container  2100 . For example, distance Dy is preferably 0 mm or more. 
         [0043]    The shortest distance in X-Y plane from one end of first cut line  223  or one end of second cut line  224  to the edge of opening  211  (distance in X direction in the present embodiment) can be appropriately determined from the intended size of the opening formed by the bending of second bendable lid part  226  and first bendable lid part  225  toward container  2100 . The shortest distance is, for example, 7.0 to 10.0 mm from the viewpoint of taking out a packaged substance having substantially the same size as that of opening  211 . 
         [0044]    Both first film layer  221  and second film layer  222  are obtained, for example, by cutting a film made of resin. Examples of the resin include polyester resins, polyolefin resins, polyamide resins, polycarbonates, ethylene copolymer, and combinations thereof. Examples of the polyester resins include polyethylene terephthalate and polyethylene naphthalate. Examples of the polyolefin resins include high-density polypropylene, low-density polyethylene, linear low-density ethylene-a-olefin copolymer, homopolypropylene, and random copolymer polypropylene formed by polymerized monomers including ethylene and propylene. The ethylene copolymer is a copolymer formed by polymerized monomers including ethylene and (meth)acrylic acid alkyl ester or vinyl ester. First film layer  221  and second film layer  222  may contain a material other than a resin, such as a layered product of metal foil and a resin-made film, in such a range that first film layer  221  and second film layer  222  can function properly. 
         [0045]    The thickness of first film layer  221  and second film layer  222  can be appropriately determined in such a range that first bendable lid part  225  and second bendable lid part  226  can achieve intended functions, respectively. For example, the thickness of first film layer  221  and second film layer  22  is 10 to 200 μm, respectively. 
         [0046]    Film  220  can be configured by forming first cut line  223  on first film layer  221  and forming second cut line  224  on second film layer  222  by half-cutting each of first and second film layers  221  and  222 , which are weakly adhered to each other, of two-layer structured film (easy-peel film). 
         [0047]    The adhesion of film  220  to an end face, on the side of opening  211 , of multi-chamber container  210  is performed, for example, by thermal fusion. By pressing film  220  toward multi-chamber container  210 , for example, with a suitable force using an elastic body made of a silicone rubber during the thermal fusion of film  220 , it becomes possible to adhere film  220  to multi-chamber container  210  as well as to the peripheral wall surface of protrusion  212 . 
         [0048]    Support frame  300  is a frame which is rectangular when viewed in a plan view, as illustrated in  FIGS. 2, 3A, and 3B . Support frame  300  has twelve holes  310  on one end face, in Z direction, of each of pairs of long side portions along Y direction. Hole  310  has a size that allows rod  252  to be inserted therein. The material for support frame  300  is not limited. Support frame  300  can be obtained, for example, by resin molding. Examples of the resin include polyolefin resins, polyamide resins, polystyrene resins, methyl polymethacrylate resins, polycarbonates, and cycloolefin copolymer resins. 
       Action 
       [0049]    Each rod  252  of engaging parts  250  at both ends of sealed container  200  is inserted into each of pairs of holes  310  disposed at corresponding positions in the pairs of long side portions of support frame  300 . This insertion allows engaging part  250  to be engaged with support frame  300  detachably, so that sealed container  200  is supported by support frame  300 , with opening  211  facing one side in Z direction ( FIG. 3B ). 
         [0050]    For example, when twelve pairs of holes  310  of support frame  300  support twelve sealed containers  200  therein, with the center-to-center distance of opening  211  in X direction being set at 9 mm and the center-to-center distance of hole  310  of support frame  300  in Y direction being set at 9 mm, the position of openings  211  of twelve sealed containers  200  supported by support frame  300  is the same as the arrangement of wells in a 96-well microplate ( FIGS. 2  A and  3 A). 
         [0051]    First bendable lid part  225  and second bendable lid part  226  usually overlap each other. In addition, first cut line  223  and second cut line  224  do not overlap each other in Z direction. Accordingly, opening  211  is usually sealed by film  220 . Chip  230  housed in each container  2100  is usually kept in an endotoxin-free clean condition. Chip  230  is, for example, taken out as follows. 
         [0052]      FIG. 9A  is a cross-sectional view schematically illustrating film  220  and pipetter  400 , with second bendable lid part  226  being slightly pressed by pipetter  400 , and  FIG. 9B  is a cross-sectional view schematically illustrating film  220  and pipetter  400 , with second bendable lid part  226  being further pressed by pipetter  400 . 
         [0053]    When second bendable lid part  226  is pressed by the tip of pipetter  400 , second bendable lid part  226  starts to be bent toward container  2100 . As second bendable lid part  226  starts to be bent, first bendable lid part  226  is bent toward container  2100  while being peeled off from second bendable lid part  226 . When first bendable lid part  225  is peeled off from second bendable lid part  226  and first and second bendable lid parts  225  and  226  are bent together toward container  2100 , an opening is formed on second film layer  222 , with second cut line  224  being a part of the end edge of the opening, and an opening is formed on first film layer  221 , with first cut line  223  being a part of the end edge of the opening. Thus, pipetter  400  is inserted into container  2100  through the opening formed in each of first and second film layers  221  and  222 . 
         [0054]      FIG. 9C  is a cross-sectional view schematically illustrating film  220 , pipetter  400  and chip  230 , with pipetter  400  being inserted into container  2100  and being attached to chip  230  inside container  2100 . When chip  230  is attached to pipetter  400 , pipetter  400  is extracted. 
         [0055]    It is possible that, when the surface of second film layer  222  is contaminated with endotoxin, a portion, at the tip of pipetter  400 , which contacts with second bendable lid part  226  may also be contaminated. However, liquid to be sucked into chip  230  when using chip  230  does not usually contact with pipetter  400 . Accordingly, chip  230  is attached to pipetter  400  in a substantially non-contaminated clean condition, regardless of the presence/absence of the contamination of pipetter  400 . 
         [0056]      FIG. 9D  is a cross-sectional view schematically illustrating film  220  and chip  230 , with chip  230  that is attached to pipetter  400  being taken out from container  2100 . Each of second and first bendable lid parts  226  and  225  bent toward containers  2100  contacts with inserted pipetter  400 . That is, the surfaces of second and first film layers  222  and  221  abut pipetter  400 . 
         [0057]    When extracting pipetter  400  from container  2100 , both first and second bendable lid parts  225  and  226  contact with pipetter  400 . Then, the friction thereof with pipetter  400  or the abutment of the tips of first and second bendable lid parts  225  and  226  with the base end of chip  230  allows first and second bendable lid parts  225  and  226  to be reversed in association with the extraction of pipetter  400 . 
         [0058]    Chip  230  attached to the tip of pipetter  400  contacts with reversed first and second bendable lid parts  225  and  226  when extracting pipetter  400 . That is, chip  230  contacts with clean rear surfaces of first and second bendable lid parts  225  and  226  when extracting pipetter  400 . 
         [0059]    Accordingly, chip  230  is taken out from each container  2100  in a clean condition without being contaminated with endotoxin. Chip  230  taken out in a clean condition is already attached to pipetter  400 , and is thus used as in the clean condition. Thus, sealed container  200  according to the present embodiment is suitable for allowing a solid material housed in a clean condition supported at the tip of a member inserted into each container  2100  from the outside of film  220  to be taken out in a clean condition. 
         [0060]    Sealed container  200  is supported by support frame  300 , and thus chip  230  is attached to all the tips of eight consecutive pipetters as described above when the eight consecutive pipetters are inserted into all of eight consecutive containers  2100 . 
         [0061]    When film  220  is cut along Y direction immediately above thin wall part  240  to break thin wall part  240 , a separate sealed container, i.e., single container  2100  sealed with a single lid made of a film including first bendable lid part  225  and second bendable lid part  226  is obtained. 
       Effect 
       [0062]    Sealed container set  100  includes sealed container  200  and support frame  300 , as described above. Accordingly, it is possible to handle sealed container  200  with opening  211  of each container  2100  facing upward, and thus it is convenient to take out chip  230  in a clean condition from each container  2100 . 
         [0063]    Sealed container  200  includes containers  2100  each having opening  211 , and film  220  adhered to containers  2100  to seal opening  211 , as described above. Each container  2100  houses chip  230 , and film  220  includes first film layer  221  adhered to containers  2100  and second film layer  222  adhered to first film layer  221 . First film layer  221  has first bendable lid part  225  which is shaped by first cut line  223  at a portion corresponding to opening  211  and which is bent toward container  2100  when being pressed toward container  2100 , and second film layer  222  has second bendable lid part  226  which is shaped by second cut line  224  at a portion corresponding to opening  211  and which is bent toward container  2100  when being pressed toward container  2100 . Further, first cut line  223  and second cut line  224  do not overlap over opening  211  in Z direction, and at least a part of first bendable lid part  225  overlaps second bendable lid part  226  in Z direction. Both second and first bendable lid parts  226  and  225  are bent toward container  2100  when second bendable lid part  226  is pressed toward container  2100 . Due to the friction with pipetter  400 , the abutment with the end portion of chip  230 , or other causes, first and second bendable lid parts  225  and  226  are, for example, dragged and reversed in association with the extraction of pipetter  400 . Accordingly, even when chip  230  taken out from each container  2100  contacts with first and second bendable lid parts  225  and  226 , chip  230  contacts only with clean surfaces, i.e., rear surfaces of first and second bendable lid parts  225  and  226 . Therefore, according to sealed container  200 , chip  230  housed in each container  2100  in a clean condition can be taken out from each container  2100  in a clean condition. 
         [0064]    It is more effective that first bendable lid part  225  is shaped by first cut line  223  in such a shape as to protrude toward one side in Y direction and second bendable lid part  226  is shaped by second cut line  224  in such a shape as to protrude toward the other side in Y direction, from the viewpoint of forming in film  220  an opening of a size closer to that of opening  211 . 
         [0065]    It is more effective for the positions of both ends of first cut line  223  in X direction to be outside the positions of both ends of second cut line  224 , from the viewpoints of disposing first and second cut lines  223  and  224  so as not to overlap in Z direction, and of forming a larger opening in film  220  in Y direction. 
         [0066]    By positioning all of both ends of first cut line  223  and both ends of second cut line  224  in X direction inside opening  211  in X direction, it becomes possible to employ the entire part of a virtual line connecting both ends of first cut line  223  as a base end portion along which first bendable lid part  225  is bent and the entire part of a virtual line connecting both ends of second cut line  224  as a base end portion along which second bendable lid part  226  is bent, respectively. Accordingly, it is more effective for first and second cut lines  223  and  224  to be in the above-described positional relationship, from the viewpoint of forming an opening in film  220  more easily than a case where the first and second cut lines extend outside of opening  211 . 
         [0067]    It is more effective that containers  2100  constitute multi-chamber container  210  in which eight containers  2100  are arranged in one direction, and that film  220  integrally seals all openings  211  of multi-chamber container  210 , from the viewpoints of further enhancing the productivity of sealed container  200  compared to a case where containers  2100  are sealed separately with a film, and of significantly reducing the risk of contamination in the production process of sealed container  200 . 
         [0068]    It is more effective that multi-chamber container  210  further has breakable thin wall part  240  connecting containers  2100  which are adjacent to each other, from the viewpoint of allowing eight consecutive sealed containers to be separately available. 
         [0069]    It is more effective that multi-chamber container  210  further has engaging part  250 , disposed at both ends of multi-chamber container  210 , for engaging with support frame  300 , from the viewpoint of enhancing the convenience of taking out chip  230  in a clean condition from each container  2100 . 
         [0070]    It is more effective for multi-chamber container  210  to further has protrusion  212  around each opening  211 , from the viewpoint of further enhancing the adhesive strength of film  220  with respect to multi-chamber container  210  due to an enlarged area for adhesion between film  220  and multi-chamber container  210  compared to a case where multi-chamber container  210  does not have protrusion  212 . 
       Modification 
       [0071]    Moreover, the embodiment of the present invention may include a further modification in such a range as to enable the effects of the present invention to be achieved. 
         [0072]    For example, an engaging part illustrated in  FIG. 10A  is composed of quadrangular prism-shaped protruding part  551  that protrudes in X direction. Further, support frame  600  illustrated in  FIGS. 10B and 10C  has recess parts  610  cut out in a quadrangular prism shape in one end portion of the inner wall surface of support frame  600 . Protruding part  551  is fit into recess  610 . Thus, the engagement of the sealed container with the support frame can adopt various modes such as a mode in which a rod is inserted into a hole, or a mode in which a convex part is fitted into a recess part. 
         [0073]    In the above-described embodiment, while both the ends of the first cut line are outside both the ends of the second cut line in the arrangement direction of the openings, it is also possible to adopt a reverse configuration, i.e., to position both the ends of the second cut line to be outside both the ends of the first cut line in the arrangement direction of the openings. This configuration also achieves the same effects of the above-described configuration in which both ends of the first cut line are outside both ends of the second cut line. 
         [0074]    The first and second cut lines may be either the above-mentioned portions which cut the film, or structures to cut the film when the second bendable lid part is pressed toward the container, for example, a break line such as perforation, and a half cut line such as a half-cut part. 
         [0075]    The shapes of the first and second cut lines in a plan view do not need to be curved. For example, as illustrated in  FIG. 11A , the shapes of first cut line  723  and second cut line  724  both may be shapes composed of two straight lines forming an angle therebetween. 
         [0076]    Both ends of one of the first and second cut lines do not need to be positioned outside both ends of the other. For example, as illustrated in  FIG. 11B , one end and the other end of first cut line  823  may be positioned in a manner to be shifted toward one side in X direction away from one end and other end of second cut line  824 , respectively. 
         [0077]    Both ends of the first and second cut lines do not need to be positioned inside opening  211  in X direction. For example, as illustrated in  FIG. 11C , both ends of first cut line  923  and both ends of second cut line  924  may be both positioned outside opening  211  in X direction. 
         [0078]    The first and second cut lines both may be disposed over opening  211 , and the second cut line may surround the first cut line. For example, as illustrated in  FIG. 12A , first cut line  1023  may be formed into a circular arc shape, and second cut line  1024  may be formed into a circular arc shape which is outside first cut line  1023 , the circular arc shape of second cut line  1024  having a larger diameter than that of first cut line  1023 . Thus, it is more effective for first cut line  1023  to be surrounded by second cut line  1024  from the viewpoint of forming a large opening of an intended shape in film  220 , because it becomes possible to form in film  220  an opening of substantially the same shape as that of the first bendable lid part. 
         [0079]    As illustrated in  FIG. 12B , the first bendable lid part may substantially overlap the second bendable lid part. Both the planar shapes of the first and second bendable lid parts are rectangular, and both the planar shapes of first cut line  1123  and second cut line  1124  are shapes each composed of three sides of the rectangle. Two opposite sides of the three sides of each of first and second cut lines  1123  and  1124  are both parallel to Y direction, and one sides between the opposite sides thereof are parallel to X direction. The one side therebetween of first cut line  1123  is positioned slightly outside both ends of second cut lien  1124 , but the two opposite sides of first cut line  1123  are positioned inside second cut line  1124 . Thus, even when second cut line  1124  is positioned outside first cut line  1123  at least in X direction, the first and second bendable lid parts substantially overlap each other, so that it becomes possible to form in film  220  an opening of substantially the same shape as that of the first bendable lid part. Therefore, in the present invention, even when one smaller bendable lid part overlaps the other larger bendable lid part in most part of the other bendable lid part (e.g., 90% or more), it can be said that the cut line of the other bendable lid part “surrounds” the cut line of one bendable lid part. Accordingly, the modification as described above is more effective from the viewpoint of forming a larger opening of an intended shape in film  220 . 
         [0080]    While  FIGS. 12A and 12B  illustrate embodiments in which the outer second bendable lid parts are larger than the inner first bendable lid part, the first bendable lid part may be larger than the second bendable lid part. Further, the direction in which the first bendable lid part is bent and the direction in which the second bendable lid part is bent may be orthogonal to each other, as in the case where the first bendable lid part is bent in X direction while second bendable lid part is bent in Y direction. 
         [0081]    While, in the above-described embodiment, the planar shape of each of the first and second cut lines is the shape of an arc having a chord along X direction, the orientation of the chord either may be in Y direction perpendicular to X direction, instead of X direction; or may be in W direction which is oblique both to X and Y directions. Further, the orientation of the chord either may be the same for all the cut lines or may be different. 
         [0082]    For example, as illustrated in  FIG. 13 , it is also possible for multi-chamber container  510  not to have the above-described protrusion, and for film  220  to be adhered to the end face of multi-chamber container  510  on opening  211  side and the end portion of the inner peripheral wall of container  5100  on opening  211  side to seal opening  211 . The length in Z direction of film  220  adhered to the end portion of the inner peripheral wall portion of container  5100  on opening  211  side (i.e., distance in Z direction of the inner peripheral wall portion to which film  220  is adhered, from opening  211 ; d in  FIG. 13 ) is, for example, 0.5 to 1.0 mm. Film  220  can be adhered to multi-chamber container  510  as described above, for example, by pressing film  220  toward multi-chamber container  510  with a suitable force using a heat-resistant elastic body such as a silicone rubber-made elastic body during the thermal fusion of film  220 . 
         [0083]    As described above, by adhering film  220  to the inner peripheral wall end portion of container  5100 , it becomes possible to adhere film  220  to multi-chamber container  510  with sufficient adhesion area, even when multi-chamber container  510  does not have the protrusion. Thus, it is more effective for film  220  to be adhered to the end face of multi-chamber container  510  on opening  211  side and the end portion of the inner peripheral wall of container  5100  on opening  211  side to seal opening  211 , from the viewpoint of enhancing the adhesive strength of film  220  with respect to multi-chamber container  510 . 
         [0084]    Containers  2100  and  5100  may be empty. Even when containers  2100  and  5100  are empty, it is possible to use opened containers  2100  and  5100  as endotoxin-free clean instruments. 
         [0085]    At least a part of the surface of the first or second bendable lid part may be composed of a resin material that exhibits strong frictional force such as rubber. This configuration is advantageous from the viewpoint of surely reversing the first and second bendable lid parts when taking out a packaged substance from the container. 
         [0086]    The film may further have a break line in the film at a position between the openings. Such a configuration is more convenient for dividing the containers into separate containers, since the film can also be teared when the thin wall part is broken. 
         [0087]    The support frame either may be bottomed, or may further has a lid. Further, the above-described shape of the break line either may be a straight line, or may be a non-straight line including a curved portion. 
         [0088]    Note that film  220  does not need to be an easy-peel film. For example, film  220  can also be formed by overlapping a film for first film layer  221  having preformed first cut line  223  and a film for second film layer  222  having preformed second cut line  224  and by thermally fusing both the films directly to the end face of multi-chamber container  210  on opening  211  side. 
         [0089]    While a mode including multi-chamber container  210  in which eight containers  2100  are arranged in a row is described above as an embodiment of the present invention, it is also possible to compose the sealed container according to the present invention of container  2100  and a portion of film  220  corresponding to opening  211 . Further, the configuration of the multi-chamber container is not limited to the configuration in which containers are arranged in a row, and the multi-chamber container may be configured such that the containers are arranged in multiple rows, or such that the openings are collected toward one side in Z direction (e.g., collected in a bundle). 
         [0090]    This application is entitled to and claims the benefit of Japanese Patent Application No. 2013-239764 filed on Nov. 20, 2013, the disclosure of which including the specification, drawings and abstract is incorporated herein by reference in its entirety. 
       INDUSTRIAL APPLICABILITY 
       [0091]    The sealed container according to the present invention enables a packaged substance housed in a container in a clean condition to be taken out from the container in the clean condition. The sealed container and the sealed container set according to the present invention are expected to be applied to technical fields where contamination by endotoxin is not permitted, such as medical tests and experiments, and pharmaceutical preparations to contribute to the further progress of the technical fields. 
       REFERENCE SIGNS LIST 
       [0000]    
       
           10  Liquid container 
           11  Liquid supply part 
           12  Container body 
           13  Frame 
           14  Sealing sheet 
           15  Evaporation prevention sheet 
           16  Through hole 
           17  Cover 
           18  Slit 
           20  Chip 
           100  Sealed container set 
           200  Sealed container 
           210 ,  510  Multi-chamber container 
           211  Opening 
           212  Protrusion 
           220  Film 
           221  First film layer 
           222  Second film layer 
           223 ,  723 ,  823 ,  923 ,  1023 ,  1123  First cut line 
           224 ,  724 ,  824 ,  924 ,  1024 ,  1124  Second cut line 
           225  First bendable lid part 
           226  Second bendable lid part 
           230  Chip 
           240  Thin wall part 
           250  Engaging part 
           251 ,  551  Protruding part 
           252  Rod 
           300 ,  600  Support frame 
           310  Hole 
           400  Pipetter 
           610  Recess part 
           2100 ,  5100  Container