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Q6.1552 | Q6 | What genes does Olaparib target when it's used to treat cancer? | When used to treat cancer, the drug Olaparib targets the genes PARP2, PARP1, and PARP3. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1553 | Q6 | What genes does Nitroglycerin target when it's used to treat congestive heart failure? | When used to treat congestive heart failure, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1554 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat attention deficit hyperactivity disorder? | When used to treat attention deficit hyperactivity disorder, the drug Lisdexamfetamine Dimesylate targets the genes SLC6A2, SLC18A2, and SLC6A3. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1555 | Q6 | What genes does Naproxen Sodium target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1556 | Q6 | What genes does Brexanolone target when it's used to treat postpartum depression? | When used to treat postpartum depression, the drug Brexanolone targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1557 | Q6 | What genes does Clozapine target when it's used to treat anxiety? | Clozapine has not been approved by the FDA as a treatment for anxiety, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DRD2 and HTR2A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1558 | Q6 | What genes does Octreotide Acetate target when it's used to treat carcinoid tumor? | When used to treat carcinoid tumor, the drug Octreotide Acetate targets the genes SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1559 | Q6 | What genes does Nilotinib Hydrochloride Monohydrate target when it's used to treat Parkinson disease? | Nilotinib Hydrochloride Monohydrate has not been approved by the FDA as a treatment for Parkinson disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1 and BCR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1560 | Q6 | What genes does Istradefylline target when it's used to treat Parkinson disease? | When used to treat Parkinson disease, the drug Istradefylline targets the gene ADORA2A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1561 | Q6 | What genes does Roflumilast target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Roflumilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1562 | Q6 | What genes does Aripiprazole target when it's used to treat Agitation? | When used to treat Agitation, the drug Aripiprazole targets the genes DRD2, HTR2A, and HTR1A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1563 | Q6 | What genes does Ketorolac Tromethamine target when it's used to treat inflammation? | When used to treat inflammation, the drug Ketorolac Tromethamine targets the genes PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1564 | Q6 | What genes does Dexamethasone target when it's used to treat Henoch-Schoenlein purpura? | Dexamethasone has not been approved by the FDA as a treatment for Henoch-Schoenlein purpura, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1565 | Q6 | What genes does Prednisone target when it's used to treat posterior uveitis? | When used to treat posterior uveitis, the drug Prednisone targets the gene NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1566 | Q6 | What genes does Celecoxib target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Celecoxib targets the gene PTGS2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1567 | Q6 | What genes does Celecoxib target when it's used to treat hepatocellular carcinoma? | Celecoxib has not been approved by the FDA as a treatment for hepatocellular carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1568 | Q6 | What genes does Ceritinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ceritinib targets the genes ALK, EML4, and NPM1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1569 | Q6 | What genes does Acetaminophen target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Acetaminophen targets the genes PTGS2, PTGS1, TRPV1, and FAAH. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1570 | Q6 | What genes does Aspirin target when it's used to treat thrombotic disease? | When used to treat thrombotic disease, the drug Aspirin targets the genes PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1571 | Q6 | What genes does Pemigatinib target when it's used to treat urogenital neoplasm? | Pemigatinib has not been approved by the FDA as a treatment for urogenital neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are FGFR1, FGFR3, and FGFR2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1572 | Q6 | What genes does Alectinib target when it's used to treat central nervous system cancer? | Alectinib has not been approved by the FDA as a treatment for central nervous system cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RET, ALK, and EML4. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1573 | Q6 | What genes does Venetoclax target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Venetoclax targets the gene BCL2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1574 | Q6 | What genes does Patisiran Sodium target when it's used to treat familial amyloid neuropathy? | When used to treat familial amyloid neuropathy, the drug Patisiran Sodium targets the gene TTR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1575 | Q6 | What genes does Ticagrelor target when it's used to treat stroke? | When used to treat stroke, the drug Ticagrelor targets the gene P2RY12. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1576 | Q6 | What genes does Lansoprazole target when it's used to treat gastroesophageal reflux disease? | When used to treat gastroesophageal reflux disease, the drug Lansoprazole targets the genes ATP4A and ATP4B. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1577 | Q6 | What genes does Everolimus target when it's used to treat gastric cancer? | Everolimus has not been approved by the FDA as a treatment for gastric cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1578 | Q6 | What genes does Axitinib target when it's used to treat head and neck squamous cell carcinoma? | Axitinib has not been approved by the FDA as a treatment for head and neck squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1579 | Q6 | What genes does Bupivacaine target when it's used to treat osteoarthritis? | Bupivacaine has not been approved by the FDA as a treatment for osteoarthritis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1580 | Q6 | What genes does Ponatinib target when it's used to treat non-small cell lung carcinoma? | Ponatinib has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1 and BCR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1581 | Q6 | What genes does Ixabepilone target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Ixabepilone targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1582 | Q6 | What genes does Thalidomide target when it's used to treat Central Nervous System Neoplasm? | Thalidomide has not been approved by the FDA as a treatment for Central Nervous System Neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1583 | Q6 | What genes does Bupivacaine Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Bupivacaine Hydrochloride targets the gene SCN4A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1584 | Q6 | What genes does Telmisartan target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Telmisartan targets the gene AGTR1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1585 | Q6 | What genes does Tramadol Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Tramadol Hydrochloride targets the gene OPRM1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1586 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1587 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat Parkinson disease? | When used to treat Parkinson disease, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1588 | Q6 | What genes does Doxepin Hydrochloride target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Doxepin Hydrochloride targets the gene SLC6A2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1589 | Q6 | What genes does Lenalidomide target when it's used to treat pancreatic carcinoma? | Lenalidomide has not been approved by the FDA as a treatment for pancreatic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1590 | Q6 | What genes does Duvelisib target when it's used to treat cancer? | When used to treat cancer, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1591 | Q6 | What genes does Montelukast target when it's used to treat Dengue Hemorrhagic Fever? | Montelukast has not been approved by the FDA as a treatment for Dengue Hemorrhagic Fever, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CYSLTR1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1592 | Q6 | What genes does Capsaicin target when it's used to treat pain? | When used to treat pain, the drug Capsaicin targets the gene TRPV1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1593 | Q6 | What genes does Testosterone target when it's used to treat Spinal cord injury? | Testosterone has not been approved by the FDA as a treatment for Spinal cord injury, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1594 | Q6 | What genes does Celecoxib target when it's used to treat Dysmenorrhea? | When used to treat Dysmenorrhea, the drug Celecoxib targets the gene PTGS2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1595 | Q6 | What genes does Dimethyl Fumarate target when it's used to treat obstructive sleep apnea? | Dimethyl Fumarate has not been approved by the FDA as a treatment for obstructive sleep apnea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is KEAP1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1596 | Q6 | What genes does Rosuvastatin Calcium target when it's used to treat Hypercholesterolemia? | When used to treat Hypercholesterolemia, the drug Rosuvastatin Calcium targets the gene HMGCR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1597 | Q6 | What genes does Cyclosporine target when it's used to treat infection? | Cyclosporine has not been approved by the FDA as a treatment for infection, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1598 | Q6 | What genes does Prednisone target when it's used to treat adrenocortical insufficiency? | Prednisone has not been approved by the FDA as a treatment for adrenocortical insufficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1599 | Q6 | What genes does Montelukast target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Montelukast targets the gene CYSLTR1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1600 | Q6 | What genes does Eribulin Mesylate target when it's used to treat lymphoma? | Eribulin Mesylate has not been approved by the FDA as a treatment for lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1601 | Q6 | What genes does Prednisone target when it's used to treat nephrotic syndrome? | When used to treat nephrotic syndrome, the drug Prednisone targets the gene NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1602 | Q6 | What genes does Topiramate target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Topiramate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, GABRA6, GRIK1, GRIK5, GRIK4, GRIK2, GRIK3, GRIA4, GRIA3, GRIA2, and GRIA1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1603 | Q6 | What genes does Isotretinoin target when it's used to treat epidermolysis bullosa? | Isotretinoin has not been approved by the FDA as a treatment for epidermolysis bullosa, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1604 | Q6 | What genes does Vemurafenib target when it's used to treat melanoma? | When used to treat melanoma, the drug Vemurafenib targets the gene BRAF. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1605 | Q6 | What genes does Siponimod Fumarate target when it's used to treat relapsing-remitting multiple sclerosis? | When used to treat relapsing-remitting multiple sclerosis, the drug Siponimod Fumarate targets the gene S1PR1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1606 | Q6 | What genes does Indomethacin target when it's used to treat pancreatitis? | Indomethacin has not been approved by the FDA as a treatment for pancreatitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1607 | Q6 | What genes does Duvelisib target when it's used to treat chronic lymphocytic leukemia? | When used to treat chronic lymphocytic leukemia, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1608 | Q6 | What genes does Cannabidiol target when it's used to treat heart failure? | Cannabidiol has not been approved by the FDA as a treatment for heart failure, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1609 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat small cell lung carcinoma? | When used to treat small cell lung carcinoma, the drug Topotecan Hydrochloride targets the gene TOP1MT. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1610 | Q6 | What genes does Dabrafenib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Dabrafenib targets the gene BRAF. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1611 | Q6 | What genes does Mifepristone target when it's used to treat Cushing syndrome? | When used to treat Cushing syndrome, the drug Mifepristone targets the genes NR3C1 and PGR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1612 | Q6 | What genes does Carbamazepine target when it's used to treat bipolar disorder? | When used to treat bipolar disorder, the drug Carbamazepine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1613 | Q6 | What genes does Vismodegib target when it's used to treat cancer? | When used to treat cancer, the drug Vismodegib targets the gene SMO. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1614 | Q6 | What genes does Lamotrigine target when it's used to treat epilepsy with generalized tonic-clonic seizures? | When used to treat epilepsy with generalized tonic-clonic seizures, the drug Lamotrigine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1615 | Q6 | What genes does Spironolactone target when it's used to treat cirrhosis of liver? | When used to treat cirrhosis of liver, the drug Spironolactone targets the gene NR3C2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1616 | Q6 | What genes does Venetoclax target when it's used to treat non-small cell lung carcinoma? | Venetoclax has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is BCL2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1617 | Q6 | What genes does Pemetrexed target when it's used to treat sarcoma? | Pemetrexed has not been approved by the FDA as a treatment for sarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1618 | Q6 | What genes does Tenapanor Hydrochloride target when it's used to treat constipation disorder? | When used to treat constipation disorder, the drug Tenapanor Hydrochloride targets the gene SLC9A3. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1619 | Q6 | What genes does Belinostat target when it's used to treat urothelial carcinoma? | Belinostat has not been approved by the FDA as a treatment for urothelial carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1620 | Q6 | What genes does Naproxen target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Naproxen targets the genes PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1621 | Q6 | What genes does Dasatinib target when it's used to treat melanoma? | Dasatinib has not been approved by the FDA as a treatment for melanoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1622 | Q6 | What genes does Mometasone Furoate target when it's used to treat Nasal polyposis? | When used to treat Nasal polyposis, the drug Mometasone Furoate targets the gene NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1623 | Q6 | What genes does Baclofen target when it's used to treat Rigidity? | When used to treat Rigidity, the drug Baclofen targets the genes GABBR1 and GABBR2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1624 | Q6 | What genes does Prednisone target when it's used to treat leukemia? | When used to treat leukemia, the drug Prednisone targets the gene NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1625 | Q6 | What genes does Megestrol Acetate target when it's used to treat intraepithelial neoplasia? | Megestrol Acetate has not been approved by the FDA as a treatment for intraepithelial neoplasia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PGR. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1626 | Q6 | What genes does Dexamethasone target when it's used to treat Waldenstrom macroglobulinemia? | Dexamethasone has not been approved by the FDA as a treatment for Waldenstrom macroglobulinemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1627 | Q6 | What genes does Cobicistat target when it's used to treat HIV infection? | When used to treat HIV infection, the drug Cobicistat targets the genes CYP3A4, CYP3A5, CYP3A43, and CYP3A7. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1628 | Q6 | What genes does Mometasone Furoate target when it's used to treat obstructive sleep apnea? | Mometasone Furoate has not been approved by the FDA as a treatment for obstructive sleep apnea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1629 | Q6 | What genes does Baricitinib target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Baricitinib targets the genes JAK1 and JAK2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1630 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat pain? | Levothyroxine Sodium has not been approved by the FDA as a treatment for pain, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are THRA and THRB. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1631 | Q6 | What genes does Zoledronic Acid target when it's used to treat bone disease? | When used to treat bone disease, the drug Zoledronic Acid targets the gene FDPS. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1632 | Q6 | What genes does Baclofen target when it's used to treat Spinal cord injury? | When used to treat Spinal cord injury, the drug Baclofen targets the genes GABBR1 and GABBR2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1633 | Q6 | What genes does Torsemide target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Torsemide targets the gene SLC12A1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1634 | Q6 | What genes does Edoxaban Tosylate target when it's used to treat pulmonary embolism? | When used to treat pulmonary embolism, the drug Edoxaban Tosylate targets the gene F10. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1635 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat severe combined immunodeficiency? | Fludarabine Phosphate has not been approved by the FDA as a treatment for severe combined immunodeficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1636 | Q6 | What genes does Cetirizine Hydrochloride target when it's used to treat urticaria? | When used to treat urticaria, the drug Cetirizine Hydrochloride targets the gene HRH1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1637 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat frozen shoulder? | When used to treat frozen shoulder, the drug Triamcinolone Acetonide targets the gene NR3C1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1638 | Q6 | What genes does Pomalidomide target when it's used to treat multiple myeloma? | When used to treat multiple myeloma, the drug Pomalidomide targets the genes CRBN, DDB1, CUL4A, and RBX1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1639 | Q6 | What genes does Colchicine target when it's used to treat prostate cancer? | Colchicine has not been approved by the FDA as a treatment for prostate cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1640 | Q6 | What genes does Vandetanib target when it's used to treat ovarian cancer? | Vandetanib has not been approved by the FDA as a treatment for ovarian cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA3, EPHB1, EPHA1, EPHB6, and EPHA10. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1641 | Q6 | What genes does Sumatriptan Succinate target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Sumatriptan Succinate targets the genes HTR1B and HTR1D. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1642 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat allergic disease? | When used to treat allergic disease, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1643 | Q6 | What genes does Spironolactone target when it's used to treat hypertension? | When used to treat hypertension, the drug Spironolactone targets the gene NR3C2. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1644 | Q6 | What genes does Ibuprofen target when it's used to treat orthostatic hypotension? | Ibuprofen has not been approved by the FDA as a treatment for orthostatic hypotension, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1645 | Q6 | What genes does Axitinib target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Axitinib targets the genes KDR, FLT1, and FLT4. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1646 | Q6 | What genes does Alogliptin Benzoate target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Alogliptin Benzoate targets the gene DPP4. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1647 | Q6 | What genes does Ondansetron target when it's used to treat Nausea? | When used to treat Nausea, the drug Ondansetron targets the gene HTR3A. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1648 | Q6 | What genes does Eribulin target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Eribulin targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1649 | Q6 | What genes does Acetaminophen target when it's used to treat T-lymphoblastic lymphoma? | Acetaminophen has not been approved by the FDA as a treatment for T-lymphoblastic lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2, PTGS1, TRPV1, and FAAH. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1650 | Q6 | What genes does Alendronate Sodium target when it's used to treat osteitis deformans? | When used to treat osteitis deformans, the drug Alendronate Sodium targets the gene FDPS. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
Q6.1651 | Q6 | What genes does Naproxen target when it's used to treat Dysmenorrhea? | When used to treat Dysmenorrhea, the drug Naproxen targets the genes PTGS2 and PTGS1. | Drug Disease Relations; Drug Gene Relations | Multi-Filter; Join |
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CARDBiomedBench
Dataset Summary
CARDBiomedBench is a biomedical question-answering benchmark designed to evaluate Large Language Models (LLMs) on complex biomedical tasks. It consists of a curated set of question-answer pairs covering various biomedical domains and reasoning types, challenging models to demonstrate deep understanding and reasoning capabilities in the biomedical field.
Data Fields
question
: string - The biomedical question posed in the dataset.answer
: string - The corresponding answer to the question.bio_category
: string - The biological category or categories associated with the question. Multiple categories are separated by a semicolon (;
).reasoning_category
: string - The reasoning category or categories associated with the question. Multiple categories are separated by a semicolon (;
).uuid
: string - Unique identifier for the question-answer pair.template_uuid
: string - Unique identifier of the original template question from which this instance was derived.
Citation
@article {Bianchi2025.01.15.633272,
author = {Bianchi, Owen and Willey, Maya and Avarado, Chelsea X and Danek, Benjamin and Khani, Marzieh and Kuznetsov, Nicole and Dadu, Anant and Shah, Syed and Koretsky, Mathew J and Makarious, Mary B and Weller, Cory and Levine, Kristin S and Kim, Sungwon and Jarreau, Paige and Vitale, Dan and Marsan, Elise and Iwaki, Hirotaka and Leonard, Hampton and Bandres-Ciga, Sara and Singleton, Andrew B and Nalls, Mike A. and Mokhtari, Shekoufeh and Khashabi, Daniel and Faghri, Faraz},
title = {CARDBiomedBench: A Benchmark for Evaluating Large Language Model Performance in Biomedical Research},
year = {2025},
publisher = {Cold Spring Harbor Laboratory},
URL = {https://www.biorxiv.org/content/early/2025/01/19/2025.01.15.633272},
journal = {bioRxiv}
}
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