Conversation: The conversation between human and AI assistant.
[|Human|] my husband takes cymbalta and has for more than 10 years. He also takes three different meds for high blood pressure and two different blood thinners. Is there significant drug interactions that would cause him to stop taking the cymbalta or at the very least switch to something else. His depression has returned and he is having sleep issues.
[|AI|]  Hi. I understand your concern. Cymbalta contains duloxetine and it is one of the good medicines for depression. If you are taking antihypertensive medicine then need to do proper evaluation of class of that medicines. There are interactions with duloxetine but still it is safe to take it under observations .SSRI sertraline / Escitalopram are safely used in hypertensive patients. Sertraline is the safest among all in cardio vascular compromised patients. Lorazepam is safest benzodiazepine for sleep problems. You can discuss all these options with your treating doctor. Still if you have a query then feel free to ask. Thank you.