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[|Human|] my mother recently had thymectomy,her biopsy report came as stage 1 BUT B3/b2 VARIANT....she had a myasthenia crisis postop and on ventilator now....based on staging and histology variant as B3 is consuidered to be a invasive variant..did she require radiation therapy..kindly help me sir
[|AI|]  Stage 1 Thomas is one which is completely encapsulated without any trans-capsular invasion or extension. Completely resected stage 1 Thomas does not require post-operative radiation therapy even in B2/B3 histological subtype. Radiation therapy is required in incomplete resection, margin positive disease on histopathology report, stage 2 to 4 disease or in thy mic carcinoma. I hope your query has been answered. If you any further question I will be happy to answer. Thank you for choosing Chat Doctor.