Conversation: The conversation between human and AI assistant.
[|Human|] Hi doctor...from past two months i developed a habit of chewing tobaco....because of which white patches have appeared inside my cheeks...i know this because of the tobacco i am consuming....so i am dropping the use of it now....and now i request u to suggest some medication or remedy for cessation of those white patches from my mouth..
[|AI|]  Heloo.pt.-A systematic review found that no treatments commonly used for leukoplakia have been shown to be effective in preventing malignant transformation. Some treatments may lead to healing of leukoplakia, but do not prevent relapse of the lesion or malignant change. Regardless of the treatment used, a diagnosis of leukoplakia almost always leads to a recommendation that possible causative factors such as smoking and alcohol consumption be stopped, and also involves long term review of the lesion, to detect any malignant change early and thereby improve the prognosis significantly. Removal of possible predisposing factors and reviewBeyond advising smoking cessation, many clinicians will employ watchful waiting rather than intervene. Recommended recall intervals vary. One suggested program is every 3 months initially, and if there is no change in the lesion, then annual recall thereafter. Some clinicians use clinical photographs of the lesion to help demonstrate any changes between visits. Watchful waiting does not rule out the possibility of repeated biopsies. If the lesion changes in appearance repeat biopsies are especially indicated. Since smoking and alcohol consumption also places individuals at higher risk of tumors occurring in the respiratory tract and pharynx, "red flag" symptoms (e.g. hemoptysis - coughing blood) often trigger medical investigation by other specialties. Surgical removalSurgical removal of the lesion is the first choice of treatment for many clinicians. However, the efficacy of this treatment modality cannot be assessed due to insufficient available evidence. This can be carried out by traditional surgical excision with a scalpel, with lasers, or with electrocautery or cryotherapy. Often if biopsy demonstrates moderate or severe dysplasia then the decision to excise them is taken more readily. Sometimes white patches are too large to remove completely, and instead they are monitored closely. Even if the lesion is completely removed, long term review is still usually indicated since leukoplakia can recur, especially if predisposing factors such as smoking are not stopped. MedicationsMany different topical and systemic medications have been studied, including anti-inflammatories, antibiotics (target Candida species), carotenoids (precursors to vitamin A, e.g. beta-carotene), retinoids (Chat Doctor.  Vitamins C and E have also been studied with regards a therapy for leukoplakia. Some of this research is carried out based upon the hypothesis that antioxidant nutrients, vitamins and cell growth suppressor proteins are antagonistic to oncogenes is. High doses of retinoids may cause toxic effects. Other treatments that have been studied include photodynamic therapy.