Conversation: The conversation between human and AI assistant.
[|Human|] Hi my mother had operation PCNL on both kidney on 25.10.11. she had stone on right kidney with moderate palvicalyceal dilatation and stone on left kidney also with normal pc system.but her s.creatinine was 1.5. she had PCNL on both kidney with DJ stent on right which was removed on 8th POD.on 15.11.11 she has done a s. creatinine level which is 1.4.(normal value 1.2).she in 58 years ,Hypertensive (on Cavapro) and DM( Amaryl 2 mg) .she also had low dose ecosprin and vastaral mr as her ecg shows septal ischaemia.(echo: normal). is the creatinine level is worried . how long it take to normalize the creatinine level after relief of obstruction.what precaution she need to have
[|AI|]  Hi, Thanks for writing in. I suspect there was a large stone causing obstruction and HY Chat Doctor.  Subsequent percutaneous nephrolithotomy (PCNL) treatment was done to treat the stone. The serum creatinine level goes up due to urinary obstruction, probably the right kidney stone in your mother. Since the obstruction was present for some time in the past, the kidney function might have got affected. As per medical literature, a kidney stone causing obstruction for more than 10 days can cause obstructive myopathy which is form of permanent damage leading to the kidney being unable to function properly. The raised creatinine is a consequence of this obstruction and a level of 1.4 is borderline high. It is most likely that the kidney was not much affected by the duration of obstruction by the stone. Serum creatinine is to be repeated after 2 - 3 months, and it will most likely come down to normal. Since she is having diabetes and hypertension, regular kidney function tests should be done every 6 months. Creatinine can also rise due to hypertension and diabetes.