Conversation: The conversation between human and AI assistant.
[|Human|] Hello,Since being diagnosed with Hypogammaglobulemia @ 53 yo , Im trying to figure out the cause: Chronic pylonephritis resulting in nephrectomy 20yrs agoFocal segmental glomersclerosis in remaining kidneyAnkylosing Spondylitis + (spinal stenosis)FibromyalgiaOsteo-Arthritis (hands, feet, knees, etc...)Any ideas?
[|AI|]  Hello and welcome to Chat Doctor, Gamma globulin is a protein produced by the liver. Hypogammaglobulinemia can be congenital or it can be acquired. Congenital hypogammaglobulinemia is due to congenital absence of production of gamma globulin and acquired can be due to liver disease. All the diseases mentioned by you-chronic pyelonephritis, glomersclerosis, ankylosing spondylitis, fibromyalgia and osteoarthritis are not directly responsible for hypogammaglobulinemia. Treatment consists of replacement with gammaglobulins. Thanks and take care Chat Doctor.