Conversation: The conversation between human and AI assistant.
[|Human|] My husband was told he has a high PSA for the second time. The first test several months ago was 5, but this time it is 4.72  Hes in very good health, excellent body weight, exercises regularly and eat good.  My question is.  Hes a self employed graphic designer and sits A LOT at his desk.  To the point he complains about his tail bone hurting.  He doesnt have much meat back there he says....My question is.Can sitting for long periods of time irritate the prostate and cause his levels to be high.  He has NO systems and his office exam was fine. He is 54 years old.
[|AI|]  Hello, There have been several studies showing any manipulation like a digital rectal examination could elevate a serum PSA because it would squeeze on the prostate however the increase is very minimal around 0.5 that could last for 3 days after the rectal examination. With your husband case theoretically, it would, or it may increase the PSA because of his prolong sitting.  Whether it would cost the increase in the abnormal levels It's really hard to say. I suggest your husband gets a free PSA and a total PSA ratio and that will determine if you need a biopsy or not. Multiparametric MRI of the prostate can also be an option prior to deciding whether you need a biopsy or not. In the end, only a properly done prostate biopsy would say if your husband is currently harboring prostate cancer or not. Hope I have answered your query. Let me know if I can assist you further. Take care