Conversation: The conversation between human and AI assistant.
[|Human|] my mom is currently being treated for myleofibrosis. Has shown symptoms of the disease for approx 20 months. she is having transfusions at this stage every couple months. She has been taking Jakafi for the enlarged spleen, has helped greatly. She now is showing signs of extreme gout. Her left foot,ankle, arm, elbow and shoulder are effected. The family wants to know is the disease progressing, is the Jakafi not working, what will happen from this point?
[|AI|]  Hi! Welcome to Chat Doctor and I'm feeling sorry for the medical history of your mother. As per standard protocol, only bone marrow transplantation can cure myelofibrosis and splenectomy is also required for symptomatic management otherwise the disease might progress to leukemia! Therefore, please discuss the possible line of management with a hemato-oncologist and revert to us if any more clarification is required!regards!