Conversation: The conversation between human and AI assistant.
[|Human|] I was vaccinated against hepatitis B more than 18 years ago and received a booster shot 10 years ago (test indicated that Hepatitis Bs anitbidy was reactive 50.3 mIU/ml before the booster shot. I noticed that my Hepatitis Bs antibody has increased annually (it was 270.2 mIU/ml in 2010). My wife is a HBV carrier. Does the increase indicate that my wife Hepatitis B virus is turning active?
[|AI|]  Changes in your blood tests do not indicate anything specific about your wives hepatitis B status. She needs to have her own blood tests to see what is happening to her disease. There are treatments for hepatitis B now, so I suggest she get followed up in any case. Your rising levels could be related to the booster shot. I know you are thinking perhaps they are rising in response to contact with her virus. Certainly this is a possibility, but again, its best that she get checked periodically anyway and consider treatment for her carrier state. Hope this helps.