Conversation: The conversation between human and AI assistant.
[|Human|] Hi is there anythink I can take I m having really bad mood swing feeling hot bad head dr said it not the change could it be methotrexate been on it since 2007 I take eight tablets 20 mg weekly please help my partner saying he leave me as I m not nice person at min
[|AI|]  Hi. I had gone through your query. Long term Physical illness may associate psychiatric co-morbidity. Depression is the commonest psychiatric illness among those patients. Methotraxate can cause mood variability and mood swings. But It is not always or difficult to separate it from natural course of psychiatric illness. Detail evaluation will give more confirmatory diagnosis. Methotrexate can cause illness that mimic psychosis. It can be treated with reduce the dose of medicines or add another medicines that control psychological illness. So consult psychiatrist for detail assessment. I hope I have answered your query. Thank you.