Conversation: The conversation between human and AI assistant.
[|Human|] My Husband blood pressure was very high 214/114 he went to the E.R.  Our family Doctor put him on 5mgs of amlodipine. Hes been on it for about 10 days. His blood pressure flucuates on day its 136/79 the next day its 154/95. How long does it take for the meds to work???
[|AI|]  Hello! Welcome and thank you for asking on Chat Doctor! I carefully passed through your question and would explain that it takes up to a week for the changes in antihypertensive therapy to show their real effect. But, as he has been on this therapy more than 10 days, no further changes to his blood pressure are expected. So, I recommend discussing with his attending physician the possibility of making some changes to his actual therapy (increase the dose to 10 mg daily or add another antihypertensive agent, for ex. an ACE inhibitor). Hope to have been helpful! Kind regards,