Conversation: The conversation between human and AI assistant.
[|Human|] Sir, i am suffering from psoriasis from last ten year. My dermatologist has recommended to take methotrexate by injection once in a week i.e.25 mg (1 ml). Is there any side effect of taking this medicine regularly? How much time it will take to cure psoriasis.- Deepak Salunke
[|AI|]  Hello, Welcome to Chat Doctor. I understand that you are having psoriasis and are concerned about the treatment. Methotrexate is a very effective Chat Doctor. The usual adult dose is 10-15 mg per week which is calculated based on the body weight. We usually start at 2.5 mg per week and if there are no side effects gradually escalate the dose. It usually takes 6 weeks (6 doses) for you to notice a significant reduction in scaling and redness. Methotrexate is a toxic