Conversation: The conversation between human and AI assistant.
[|Human|] My sister just had an MRI and it states the ill-defined high T@/Flair signal areas in cerebral white matter bilateraly, especially in the frontal lobes. Would you put this in simple terms. She was diagnosed w/a grade II astrocytoma in June 2011 & underwent radiation. Currently on Avastin.
[|AI|]  Hello, I think you have a typo in your statement. You may have meant to say T2 flair signal areas in the cerebral white matter.  In plain terms? Well, your sisters brain lobes in the front (on both sides) are demonstrating what is referred to as white matter degeneration which means that either the capillaries feeding the deeper parts of the brain are clotting off and causing the very smallest of infarcts or that the neurons are losing their protein insulation coverings which is technically referred to as declination.  Radiation therapy to the brain is known to cause radiographic signs of white matter degeneration within 18 months of receiving the treatments so I'm not surprised at the read given her treatment that was given.  It is not suggesting that there is any recurrence of a tumor if that's what you may be concerned about right now. Hope I have answered your query. Let me know if I can assist you further. Take care.  Chat Doctor.