Conversation: The conversation between human and AI assistant.
[|Human|] About 10 years ago I had a chancre in my genital area which went away on its own, about a year later I was sick for a week with high fever, I lost weight and had rash in my hands now after 10 years I think I have a syphilis infection left untreated I had an RPR that came back non reactive and I am now waiting on the results of a second test called Anti-nuclear antibody, my question is will this test detect dormant syphilis?
[|AI|]  Hi, Welcome to Chat Doctor. Antinuclear antibodies are abnormal antibodies present which have the ability to bind to certain structures within the nucleus of body cells. These antibodies are more common in autoimmune disorders like SHE, Rheumatoid arthritis, Graves disease and Hashimoto Thyroiditis. These antibodies do not detect dormant syphilis. RPR is a screening test which detects regain antibodies seen in syphilis. These tests have to be confirmed by specific tests like TPA, ELISA and Fluorescent treponemal antibody test. Thanks.