Conversation: The conversation between human and AI assistant.
[|Human|] looking for symptoms of MS, ESPECIALLY LIKE A POSITIVE MRI OF THE BRAIN SHOWING LESIONS SLIGHTLY ENLARGING YEAR AFTER YEAR...T2 FLAIR ALSO HAVE ENLARGED OPTIC NERVE BLURRY VISION SLURRED SPEECH AT TIMES, SEVERAL FALLS DO TO NUMBNESS WHILE STANDING UP? I WOULD LIKW UR OPINION
[|AI|]  Hi, Thank you for your query. I can understand your concerns. Multiple sclerosis (MS)-Visual blurring occurs from ON (Optic neuritis). ON is common at the onset of disease but uncommon during the later course of the disease. Visual symptoms are generally monocular but may be bilateral. Speech problem (slurred speech) & Ataxia (recurrent falls) may occur from cerebellar lesions. Brain-stem involvement can cause vertigo, vertebro-basilar insufficiency again contributing to recurrent falls. Brain-stem lesions can also cause paroxysmal symptoms like dysarthria (speech problem).MRI brain in MS-characteristic abnormalities are found in >95% of patients although more than 90% of the lesions visualized by MRI are asymptomatic. Lesions larger than 6 mm located in the corpus callosum, periventricular white matter, brain stem, cerebellum, or spinal cord are particularly helpful diagnostically. Evidence for dissemination in space in the brain (lesions slightly enlarging year after year) based on T2+ lesions in the characteristic periventricular, juxtacortical, or infratentorial regions -suggest insidious neurologic progression of MS [Primary progressive MS (PPM)]. T2-images inflammation and declination better. FLAIR(fluid attenuated inversion recovery) image-edema and gloss appear hyper-intense. Regards