Conversation: The conversation between human and AI assistant.
[|Human|] my husband has had a chronic skin rash for 8 months andnow ha pussy postules in the palm of his hands and his genitalia. very itchy all over body. has been to a dermatologist, but no help. he is a cll patient. can not figure what is causing the rash.60 years old.
[|AI|]  Hello, Looks like secondary cutaneous changes, manifesting like purpura, vasculitis, exfoliating erythroderma, etc. Avoid taking purine analogs & alkylating agents.  Get a follow-up physical examination done by your treating doctor to rule out skin infiltration with beta lymphocyte(Malignant/non-malignant disorder) often seen in CLL patients. Your husbands' treatment will depend upon the type of skin manifestation detected & investigated.  It can be harmless(insect bite/allergic rash) but if detected malignant it will require immediate treatment without delay.  Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor.