Conversation: The conversation between human and AI assistant.
[|Human|] Have you ever seen a patient who was allergic to titanium?  I had a knee replacement 3 years ago and am plagued with severe swelling and an ugly red rash on that leg.  I had the Melissa test and it showed I was allergic to titanium.  Yet, several doctors have told me this is impossible and that what I have is an infection.  I do not have pain, but stiffness when the swelling gets severe.  My Dr. has drained it several times and found the fluid full of "rice bodies".  I do NOT have Rheumatoid Arthritis.  In general, I am not an allergic person, but I am allergic to eye shadow.  I consulted a doctor who specializes in "revisions" and he declared it to be an infection and wants to replace it with another titanium prothesis.  I just need some answers.  The fluid from my knee has been cultured 8 times and never shown any infection.  Any advice would be welcome.
[|AI|]  Hello, I have studied your case. It can be metalloid or infections pre your history infection needs to ruled out by tests DO NOT IGNORE INFECTION IN POST TAR. You may need to investigate like CRP, CBC, ESR,three-phase bone scan PCR culture is very useful to find culprit organism. If infection is confirmed then debridement is required. Persistent infection revision operation is required. If metalloid confirms we will discuss again Hope this answers your query. If you have additional questions or follow-up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Wishing you good health. Take care