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[|Human|] I stopped taking Letrozole 2 weeks ago. I had been taking it since Feb 2014. In April, my Alkaline phosphatase was 71 U/L. Today, it was 125 U/L, my AST/SGOT is 1450 U/L and ALT/SGPT is 682. I have had multiple symptoms-muscle aches in legs, arm, shoulders to the point my gait was altered and I started limping, cold flashes sometimes with hot flashes and last night pain between my breasts, a back ache and nausea. I had a complete workup with CT on my lungs, Chest x-ray, Ultrasound of my liver, right kidney and large bile duck and EKG monitoring overnight. Everything was negative and the medical team at our local hospital diagnosed the adverse drug reaction. How long before the Letrozole is out of my system and is there anyway to predict how long b/4 my liver tests are more normal? I am 67 with a history of breast CA, both breasts removed. Drs. plan to monitor my liver tests and I am calling the oncologist tomorrow am. Many thanks
[|AI|]  Welcome to Chat Doctor. Thank you for posting your question. I can understand your concern. I can understand that you are very anxious about your health. Jaundice can be due to many causes like Hepatitis, gall stone disease(acute cholecystitis), pancreatitis - to name a few. Mere dietary adjustments often cannot cure it. It would have been great had I examine you on my own. You need to undergo a few tests to find out the exact cause. I would suggest you to - Avoid oily, fatty food- Chat Doctor. Stop alcohol-Have a BLAND DIET.- Repeat the abdominal ultrasound, Complete blood count, Liver function test, platelets, urea, creatinine, electrolytes done - This will help in the diagnosisVisit a gastroenterologist. He or she can examine you and correlate clinically. Consult with your oncologist. Do not worry. Hope this answers your question. If you have additional questions or follow-up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health.