Conversation: The conversation between human and AI assistant.
[|Human|] My father has been on Seroquol for 12 months. He also has been diagnosed with demina.  He now is rarely getting out of bed and never wants to leave the house. He is 75.  After researching this drug I feel he shouldnt not be on this drug  he takes 200 mg. At bedtime. How should he come off this drug.  He was put on the drug after an episode of anger and was hospitalized in a local faculty.
[|AI|]  Hello, Unwillingness on the part of patient on Seroquel can be due to two reasons:1. The sedative effect if seriously may lead to lethargy and the patient is not willing to fight back and sleep all time, 200 mg is a high dose for someone of his age.2. Due to depression creeping up and causing lethargy and weakness and reduced interest to do any work or talk to anyone. So, just by ruling out depression we can conclude that it is a sedative effect of Seroquel and can try to reduce it. Start the reduction after discussing the possibility with his treating team.  I prefer doing it by taking out 50 mg at a time and monitoring the response. Hope this helps you.