Conversation: The conversation between human and AI assistant.
[|Human|] Is it safe to occasionally 1-2 times monthly take Cialis while taking daily regiment of 50mg Losartan 1x daily with 50mg Metropolol 2x daily? This medication is being taken for controlling a High blood pressure in conjunction with irregular heart beats in 50 yr male.
[|AI|]  Hello! Thank you for asking on Chat Doctor! I understand your concern and would explain that calls interacts with both metoprolol and losartan by pharmacological synergism, leading to an increase of their effect on lowering blood pressure. This means that you may be at risk of low blood pressure when taking Calls while on this antihypertensive therapy. Although, Calls intake is not contraindicated in this case. It should be used with caution. I recommend to closely monitor your blood pressure during taking Calls. If your blood pressure doesn't decrease in a noticeable way, there is nothing to worry about it. Hope to have been helpful! Best wishes!