Conversation: The conversation between human and AI assistant.
[|Human|] Hello sir, my ESR is 120, CRP is 98 and HLA B27 is positive. So doc suggested me to take 1. Saaz 500 mg 2times a day, Naproxen 500mfg 2 times a day, Methotrexate 15mg once a week, folic acid 5mg once a week and depo-medrole inj 80mg once a week for 4weeks. I have been taking this course for more then 1 month but there is no relief from cronic pain in both knees, ankles of both legs and middle finger with heavy swelling. So plz suggest me what should I do. Thanks and regards - Sachin
[|AI|]  From the test results that you have mentioned you have peripheral arthritis as seen in RA but the HLA b27 is typically positive in Ankylosing spondylitis. The 2 disease can occur together in a person but rarely. You have any other symptoms like urethritis, psoriasis,lower back pain?the treatment you are receiving it takes time to improve condition. Get your painful joints X-rays done. Keep taking the medicines and do not stop it in between. Visit a physiotherapist it will help as exercising is good,it'll release the stiffness. You might have given next appointment in 2-3 months and would have advised to carry recent blood tests that are advice by your doctor. For this it's always better to see a rheumatologist if you have not yet.