Conversation: The conversation between human and AI assistant.
[|Human|] Hi dr. my name is David, age 22. i love a girl who has sickle cell anemia . she has mucChatDoctorplications, she had regular pain in legs and hands, swellings, pain killer do not relief her? what is the better treatment ? how much is the possibilities that my child will have sickle cell anemia?? i need your help...
[|AI|]  Hi welcome to Chat Doctor, I am Chat Doctor Sickle cell anemia is an inherited abnormality in production of hemoglobin. In this disease the normal biconcave shape of RBC is changed into Sickle shape due to mutation in the gene responsible for hemoglobin synthesis. It leads to obstruction of microcirculation and hemolytic anemia.  Now, there are 2 conditions related to this disease. One is homozygous state where patient has total inability to form normal hemoglobin and a heterozygous state where patient has mild inability to form normal Hemoglobin.  Transmission of this disease depends on both the parents. If one is homozygous and other is normal then chance of the baby to have the disease is 100%. If one is heterozygous and other is normal then chance of the baby to get the disease is 50%.  So, you have to know the genetic status of you and your girlfriend. Only then the chance of your baby to have this disease can be said.  Regards.