Conversation: The conversation between human and AI assistant.
[|Human|] My husband was diagnosed with prostate cancer 6 years ago and has been on Zoladex and Casadex ever since. These were no longer doing the job and his PSA started rising to 11 in June 2010. So he had a bone scan and Pelvic MRI which showed no spread. He then had 19 doses of Radiotherapy. After 6 weeks he had a PSA test which has come back at 42.This seems very high to us, is this normal. What reading should we expect after Radiotherapy
[|AI|]  Thanks for your question on Chat Doctor. I can understand your concern. PSA (prostate specific antigen) is marker for prostate cancer. And its value correlates with activity of cancer. High PSA level suggests higher tumor burden. And after radiotherapy, PSA level should be decreased. But in his case, its value is increased. It suggests that tumor is not responding to radiotherapy. In my opinion, he should undergo PET scan to rule out local tumor size and distant metastasis. So better to consult oncologist and discuss all these. Hope I have solved your query. Wishing good health to your husband. Thanks.