Conversation: The conversation between human and AI assistant.
[|Human|] Yes maybe...my Dad just told me he has non cancerous m spikes...and will be monitored for the next 2 years via blood test and they did an full skelital x ray of him. What does this really mean and what are the chances of this becoming cancerous...and if it is, is it treatable? Thanks! Lori Kiel
[|AI|]  Thanks for your question on Chat Doctor. M spike on electrophoresis is the diagnostic criteria for multiple myeloma. This is due to high levels of immunoglobulin (protein s), which gives positive spike on electrophoresis. But when the level of immunoglobulin s are high but not very high as seen in multiple myeloma, it gives non-specific (non-cancerous) M spike. It is seen commonly in infection and inflammation.  So this is not cancer. So no need to worry much for non-cancerous spike. Very fewer chances of it to turn into malignancy. Regular follow up with electrophoresis and bone scan is needed to diagnose multiple myeloma in such cases.