Conversation: The conversation between human and AI assistant.
[|Human|] My sister has been fighting bile duct cancer for 3+ years. She has been retaining fluid in her abdomen, which I believe is called ascites. She has been to the doctor and has had her abdomen drained twice, 5.1 liters and 6 liters respectively. She has lost a lot of weight, is fatigued, and seems very uncomfortable. She has recently had a home health nurse drain 1.0 liter (twice) from a drain in her abdomen and is on schedule to have it drained every other day. I m sure she is nearing the end, and was wondering how much longer she may have considering the fluid can not be drained fast enough. Thank you
[|AI|]  Thanks for your question on Chat Doctor. Bile duct cancer most commonly involves liver. Almost 90% bile duct cancer metastasize to liver by the time of diagnosis. And it starts deteriorating liver function. So synthetic functions of liver like albumin production decreased Chat Doctor.  This is the main reason for ascites in this kind of patients. Another possibility is malignant spread in peritoneum. So in both ways' ascites can develop. And both carries the worst prognosis. Life expectancy with ascites in bile duct cancer patients is less than 1 year.