Conversation: The conversation between human and AI assistant.
[|Human|] I have CKD/FSGS with a GFR of 37 and creatinine of 1.7 as of 2/2012. The last 2-3 weeks I have noticed that my urine is darker, more of an orange color, I have decreased urine output and my hands and feet are peeling. Could this mean that there is something going wrong that I need to discuss with my Neph?
[|AI|]  Hello, FSGS/CKD is progressive condition. But serum great of 1.7 is not a very serious issue. But we have to see if serum creatinine is progressively rising or the proteinuria is increasing. Such situation requires urgent measures. Dark urine does not signify severity of disease. Decrease urine with peeling f skin can occur due to persistent swelling as a part of the FSGS (nephrotic syn Chat Doctor.  Definitely you should consult the nephrologist.