Conversation: The conversation between human and AI assistant.
[|Human|] My dad has been diagnosed with colon cancer and it mestatized to his liver. he had a liver ablasion and is now on blood thinners (Proxaparin shots and Warfarin) but his levels are not at a therapeutic level. What could be the cause of the blood thinners not working/
[|AI|]  Himost of the blood thinners have an action for meatbolisation as well as degradation in the liver. All the clotting factors are also dependent on the liver functioning, with liver metastasis and ablation with diagnosed colon cancer, the whole hemopoietic system of the body remains deranged. Hence there is discrepancy with the achievement of therapeutic levels of the blood thinners. Regular coagulation profile studies with dose adjustment of blood thinners will be of help. All the best take care