Conversation: The conversation between human and AI assistant.
[|Human|] Hi, My mother is 57 years old and she is suffering from schizophrenia for last 35 years. she had been taking olanzapin 7.5 mg for last three years.because of no improvement in auditory hallucination , she has been advised by doctor to start taking clozapine along with olanzapin. doctor has advised to start clozapin from 12.5 mag and increase it to 50 mg within 2 weeks and also take olanzapine same does. another doctor has told me that olanzapine and clozapine should not be given simultaneously because of same group. I dont know what should be done. I dont know whether my doc wants to replace olan with clozapine or he wants a combination of both. My mother has started taking clozapine for last 3 days. Please advice. please advice.
[|AI|]  HI suit.pH. THANKS FOR YOUR QUESTION. CLOZAPINE IS A ANTIPSYCHOTICS WHICH USUALLY GIVEN TO A CASES OF RESISTANT SCHIZOPHRENIA BUT BEFORE THAT IT IS RULE THAT LEAST TWO ANTIPSYCHOTICS WITH ADEQUATE DOSES HAVE TO BE TAKEN BY THE PATIENT BUT I THINK IN YOUR MOTHER THAT Was not DONE.BUT IF YOUR DOCTOR START CLOZAPINE THEN It's OK.YOU SHOULD CONTINUE IT.DOSE CAN BE INCREASED UNTO 225-300 MG AND THERE IS AS SUCH NO CONTRAINDICATION OF GIVING IT WITH OLANZAPINE BUT WHAT WE PSYCHIATRIST USUALLY DO WE GRADUALLY Increase THE DOSES OF CLOZAPINE AND AS HALLUCINATION REDUCES WE GRADUALLY STOP THE OLANZAPINE BY TAMPERING ITS DOSES AND KEEP THE PATIENT IN ONLY CLOZAPINE.BUT YOU PROBABLY KNOW CLOZAPINE HAS GOT A VERY BONE MARROW SUPPRESSING EFFECT SO EVERY PATIENT ON CLOZAPINE SHOULD DO A BLOOD HE, WBC COUNT EVERY WEEK FOR FIRST 6 MONTHS AND THEN EVERY TWO WEEKLY STILL THE THERAPY CONTINUE. THANKS Chat Doctor.