Conversation: The conversation between human and AI assistant.
[|Human|] I suffer from chronic kidney disease. I have only one kidney that has had a consistent gfr of 39 but it has now dropped to 23.5 in two weeks. CT scan shows cortical atrophy and an ultrasound shows cortical lobulation. I previously was diagnosed with FSGS. Could all this be happening as a result of the FSGS. I should mention my BUN was 33 and creatinine is 2.4 Thanks!
[|AI|]  Dear Patient, FSGS is a though disease, and it is just a histological diagnosis since may belong to several etiologies. Was it secondary to hypertension? Was it defined as primary? Please send me every detail that can be useful to give you an opinion, included serum albumin, urinalysis, actual 24h proteinuria, autoimmunity, etc. In general, the only validated approach is ACE inhibitors or Spartans at the highest tolerable dose. Moreover, avoid NSAIDs, control hypertension, make sure the general risk factors for cardiovascular disease does not apply to you. Let me know,