Conversation: The conversation between human and AI assistant.
[|Human|] hi my sister has been uder a doctors care here in santa maria (laggattuda) pain management she has cronic back pain and now has developed adema he has perscribed methadone for pain but she can not function when on it she has swollen ankels due to the adema. can you help? thank you
[|AI|]  Everybody's chemistry is different, and your sister may have a reaction to Methadone that results in edema. Ankle edema is often a side effect of anti-inflammatory medications, or NSAIDs (such as Ibuprofen or Naproxen). There are many pain medicines to choose from beyond Methadone. And it sounds like the Methadone might be too sedating? Another newer option that has been well tolerated is Junta, whicChatDoctores in long and short-acting form. I would give that a try. Non-pharmaceutical options should have been tried also, including a TENS unit, or even a lumbar traction unit.