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[|Human|] so my mom went to her DR (NP) and had some blood work done and came back with a low WBC. She had her thyroid removed and on synthroid and I believe on metformin. She had been tire and fatigued lately and I know she really does eat well and she does smoke. Her NP told her that leukemia my be a reason for the low WBC and would refer her to a CA specialist if needed. I told her to get a second opinion. I do know that leukemia increases the WBC and they are not productive in this sense. I also know my mom has been sick with colds and not feeling well so maybe this could be of some reason to the low WBC and fatigue. So would the synthroid and metformin cause a low WBC count I cant remember all meds shes on. Also has RA, and recent neck fusion, kidney problems to name a few
[|AI|]  Thanks for posting on ChatDoctorNOrmally leukemia will show as high white cell count & not low (unless leukemic patient had aggressive chemotherapy)You are quite right that recurrent viral infections can lead to low WBC & subsequent fatigue. Due to her being on metformin & also having some other chronic medical conditions (RA, kidney problems etc.) - she must undergo few other blood tests if not already done - FBE, Fe ferritin, it D, ESR CRP, Lots, kidney tests, TFT. Hope this is helpfulThanks