Conversation: The conversation between human and AI assistant.
[|Human|] hi ,i am 28 yr female.i am suffering from psoriasis from more than last 15 yrs. already hve tried all the forms of medicines like ayurveda ,homeopathy ,& allopathy out of which homeopathy lead to severe flaring up of disease.plz tell if i ever be able to get rid of this disease,.right now i have this disease in both of my soles & on leg also.plz suggest me the best possible treatment for psoriasis in delhi.
[|AI|]  Hello and welcome to Chat Doctor I can understand your concern and frustration regarding the chronicity of psoriasis. Psoriasis has a chronic course, the course being fluctuated by remissions and relapses, however there is no permanent cure for psoriasis. Psoriasis is characterized by the presence of well-defined, thick scaly plaques mainly involving the scalp, and extensor surfaces like hands, feet/soles, elbow, knee, lower back etc. Specific topical treatment options for psoriasis plaques affecting the soles and legs includes potent topical steroid, either plain or in combination with salicylic acid. Topical vitamin D analogues like calcitriol, calcipotriene etc. are also effective for localized plaque psoriasis affecting the soles and legs. Oral agents include Immunosuppressive like methotrexate, Oral retinoids(Accretion). Although they are mainly indicated for widespread disease involvement, however, they can be used for limited yet disabling disease involving the palms and soles. Biologics like Infliximab, Golimumab, Evanescent are newer remedies and includes monoclonal antibodies, interleukin, interferons and colony stimulating factors etc. Treatment depends on the severity of the disease. While limited disease can be managed with just topical, widespread or extensive disease may require hospitalization. I would suggest that you seek an appointment with a dermatologist in your vicinity, who would be able to assess the severity of your disease and advice accordingly. Hope this helpsRegards