Conversation: The conversation between human and AI assistant.
[|Human|] I WOULD LIKE TO KNOW ABOUT BIPOLAR THAT IS UN TREATED WITH MEDS AND HE ALSO HAS PTSD NON MILITARY AND WHAT ARE THE SIDE EFFECTS OR HOW DOES VICODIN EFFECT HIM HE HIS TAKING THIS FOR A KNEE INJURY THAT IS RATHER PAINFUL HE IS IN ALOT OF PAIN I HAVE NOTICED SOME CHANGES IN HIS MOOD WITH ME LATELY IS THIS DUE TO THE PAIN ??
[|AI|]  Hi, As you describe your dear one is suffering from Knee pain, Bipolar disorder and PTSD. The Vicodin contains codeine which is an opioid. Opioids are known to precipitate mania. The stressors due to pain, due to medicine and due to PTSD all may additively fuel up an affective episode. May it be depression or mania. You have not mentioned the eat reason for not taking medicines for Bipolar disorder. My suggestion is to start him on a prophylactic dose of mood stabilizer like Sodium valproate or carbamazepine. These may also have added effect on controlling pain apart from preventing a relapse of mood symptoms. Visit a psychiatrist before starting medicines as the dose needs to be set depending on the dose of Vicodin.