Conversation: The conversation between human and AI assistant.
[|Human|] The flesh of My left palm itch, (not the skin, but beneath it) especially the area adjacent to the thumb and between the index finger and the thumb.  It feels like a deep seated urticaria. This happens especially after i exert pressure with my left hand eg. Lifting a heavy frying pan by the handle, squeezing dry thick rough cloths, or hitting something with the left palm. The itch can last for hours, it lasts longer if i can not resist scratching or massaging it. The palm can swell up and causes numbness of the fingers, especially at night. The numbness can turn to pain and it wakes me up at night. My palm and fingers can swell and at times, i cant wear my wedding ring. This has been going on for 6 months now.
[|AI|]  Hi, It seems that you are having pressure urticaria. If it occurs immediately after pressure, it should not be confused with dermatographism. It should not be confused with vasculitic urticaria., in which the lesion remains for long time, more than 48 hours. There may be severe itching, tingling and numbness and pain in pressure urticaria. If it occurs after 4 to 6 hours, then it is considered delayed pressure urticaria. You should attempt to limit pressure stimuli. The results of pharmacologic treatment of delayed pressure urticaria (DPU) are somewhat disappointing. Besides antihistamines, you may use systemic corticosteroids, non-steroidal anti-inflammatory Chat Doctor. Consult a dermatologist or allergist for evaluation for other causes of urticaria. I hope you might be satisfied with my answer. Regards.