Conversation: The conversation between human and AI assistant.
[|Human|] What treatment is suggested for a mast cell tumor that was a grade 2 mitotic index 9?  The tumor was on his back leg and they were unable to get better margins because of location.  Would you recommend radiation, chemo, palladia, or just let it heal?  I have a 10 yr old chocolate lab.  Just wondering statistical outcomes on each treatment.Thanks for your information.
[|AI|]  Thanks for your question on Chat Doctor. I can understand your situation and problem. Mast cell tumor is aggressive skin tumor. Without treatment, it will surely worsen. The best treatment is unblock surgical removal of involved skin. Since you have unresectable margins, we can try preoperative radiotherapy and chemotherapy to decrease the size of tumor. By doing this, we can achieve good margins and thus surgery can be possible. With unblock surgery, life expectancy is almost 3-4 years.  Five year survival rate is 50-60%. So better to first go for chemotherapy and radiotherapy to decrease the size of tumor and then go for unblock surgery for better outcome.