Conversation: The conversation between human and AI assistant.
[|Human|] MY TWO UNCLES FROM A FAMILY OF SEVEN SIBLINGS , DEVELOPED A HEREDITY  PARALISING CONDITION WHEN THEY BEGAN PUBERTY, 15/17 YRS OF AGE,  IT BEGAN IN THEIR HIPS AND LOWER LIMBS,(ARMS)   SHOULDERS AND UPPER LIMBS (ARMS) PRIOR TO THIS TIME THEY WERE BOTH OUTSTANDING ATHLETES,THEY EVENTUALLY BECAME WHEELCHAIR BOUND,     iT NEVER EFFECTED THEIR HEALTH IN ANY OTHER FORM, AND BOTH LIVED LONG LIVES, INTO THEIR 70/80s, I WAS VERY YOUNG AT THE TIME OF ALLTHIS OCCURENCE, AND DO KNOW A LOT FROM FAMILY MEMBERS BESIDES WITNESSING MIDDLE YEARS,   I DEFNITELY KNOW IT WAS HEREDITY, AND WAS CARRIED BY THE FEMALE AND PASSED ON TO THE MALES , IN VERY RARE CASES THE FEMALE COULD ALSO INHERIT. IAM CURIOUS TO KNOW  A DIAGNOSIS AS TO THIS AFFLICTION THIS WAS MANY YEARS AGO AND NOBODY SEEMED TO HAVE A NAME FOR THE CONDITION AT THE TIME.
[|AI|]  Hi, Thank you for posting your query. There are two common naturopathies that are hereditary in nature. The first one is called as HMSN- hereditary motor sensory neuropathy. In this condition, the weakness and numbness are more in legs, as compared to the hands. Thinning of muscles is also noted. The other type of inherited neuropathy is called as SAN- hereditary sensory autonomic neuropathy. In this condition, numbness is associated with autonomic symptoms such as postural giddiness, bladder symptoms, erectile dysfunction, etc. Motor weakness is not a feature in SAN. So, I feel they had a form of HMSN. I hope it helps. Please get back if you require any additional information. Wishing you good health, Chat Doctor. Ly/