Conversation: The conversation between human and AI assistant.
[|Human|] my father is having cronic infection in kednieys for which treatment is going on..last overdose of some medicine reduce wbc count to 500 and he was in ICU..now wbc count is 5000 and he is better but he is continually having fever..what could be the reason
[|AI|]  Hello, Most time fever suggestive of infection in body somewhere, but not always. Sometimes due to inflammatory response of body show temperature. In your case, the Kidney infection could be the main cause of fever. But you also mentioned the TLC count was very low initially. This low count itself causes fever called neurogenic fever. Mostly seen in chemotherapy induced or in Malignancy. In your case, it may be due to antibiotics. As you asked about duration of fever regarding kidney disease. Actually it depends on the type of pathology in kidney. The infection in kidney for prolonged time itself is a very high risk condition. Because this will lead to damage if kidney irreversibly and patient may develop chronic kidney disease and dialysis. Or may sometimes this infection spread all over body called sepsis and may be life-threatening. So proper work up is necessary to find out the extant of kidney infection and to find out exert pathology with organisms. So that proper treatment should be initiated according to severity and specificity of antibiotics depends on organism. So go for CT Abdomen for Extent of damage and Urine culture for specific organism and specific Chat Doctor.  In this case better start Clindamycin and antifungal