Conversation: The conversation between human and AI assistant.
[|Human|] Doing well Now 6 weeks on Ceritinib for stage IV NSCLC with some bone and marrow involvment. dx 2/15/14 alk pos.previous tx crizotinib 22month before progression, I am chemo; radiation naive; had total hyst for adenocarcinoma 1 year after dx 9/1011 T1A ... Labs from 8/4/14 liver enzymes starting to rise..ast 72, alt 78, Alk phos 372....new this last month immature granulocyte .90 absolute .10. neuts 77.8 lymps 11.5, absolute neuts 8.8 absolutes monocytes 0.7. labs taken at tail end of a week long virus..fever 101, cough malaise...now resolved. Cerritinib is more toxic but doing well in general...ca125 860 six weeks ago now 44. WBC 11.2 should I be concerned for any underlying other issues? thanks CJD
[|AI|]  Hi, GOT and SGPT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests.  So the next step is to look for certain liver damage and most common case is fatty liver disease.  It should be confirmed by ultrasound. Other causes are viral hepatitis, cirrhosis, medications, alcohol intake or autoimmune diseases.  To verify exact cause, US, bilirubin levels and tumor markers should be additionally done Then appropriate treatment can be started. Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor.