| { |
| "CO2H-tBu deprotection": [ |
| 1309, |
| 228, |
| 51, |
| 1518, |
| 563 |
| ], |
| "Triflyloxy Sonogashira coupling": [ |
| 31, |
| 28, |
| 17, |
| 94, |
| 13 |
| ], |
| "CO2H-Me deprotection": [ |
| 44348, |
| 48540, |
| 35741, |
| 5697, |
| 38698 |
| ], |
| "Grignard + acid chloride ketone synthesis": [ |
| 54, |
| 4, |
| 3, |
| 11, |
| 27 |
| ], |
| "Friedel-Crafts acylation": [ |
| 238, |
| 517, |
| 27, |
| 203, |
| 429 |
| ], |
| "Bromo Grignard reaction": [ |
| 1805, |
| 3679, |
| 4827, |
| 2278, |
| 6630 |
| ], |
| "Pinner reaction": [ |
| 26, |
| 653, |
| 1731, |
| 1393, |
| 1138 |
| ], |
| "Sulfanyl to sulfonyl": [ |
| 39, |
| 55, |
| 195, |
| 86, |
| 26 |
| ], |
| "Ester Schotten-Baumann": [ |
| 1519, |
| 6224, |
| 1584, |
| 5881, |
| 5635 |
| ], |
| "Weinreb ketone synthesis": [ |
| 2472, |
| 1083, |
| 177, |
| 1881, |
| 2196 |
| ], |
| "Isocyanate + amine urea coupling": [ |
| 4090, |
| 12403, |
| 2582, |
| 9606, |
| 11850 |
| ], |
| "Sulfonamide Schotten-Baumann": [ |
| 12601, |
| 4558, |
| 3003, |
| 14935, |
| 18965 |
| ], |
| "Mitsunobu sulfonamide reaction": [ |
| 81, |
| 238, |
| 103, |
| 389, |
| 284 |
| ], |
| "Iodo N-alkylation": [ |
| 7428, |
| 5977, |
| 2664, |
| 6065, |
| 5820 |
| ], |
| "Hydroxy to chloro": [ |
| 858, |
| 2745, |
| 1093, |
| 2874, |
| 2799 |
| ], |
| "Ketone Dess-Martin oxidation": [ |
| 2654, |
| 292, |
| 2495, |
| 2600, |
| 700 |
| ], |
| "Iodo Miyaura boration": [ |
| 273, |
| 373, |
| 125, |
| 83, |
| 236 |
| ], |
| "SNAr ether synthesis": [ |
| 24867, |
| 17691, |
| 41943, |
| 36500, |
| 14392 |
| ], |
| "Bromination": [ |
| 11216, |
| 5313, |
| 13809, |
| 12588, |
| 12713 |
| ], |
| "CO2H-Et deprotection": [ |
| 3665, |
| 15010, |
| 2103, |
| 20673, |
| 26290 |
| ], |
| "N-Cbz deprotection": [ |
| 548, |
| 135, |
| 432, |
| 1161, |
| 1470 |
| ], |
| "Sulfonic ester Schotten-Baumann": [ |
| 10311, |
| 6967, |
| 16358, |
| 12964, |
| 15035 |
| ], |
| "Fischer-Speier esterification": [ |
| 585, |
| 1084, |
| 571, |
| 1010, |
| 3051 |
| ], |
| "Bromo Buchwald-Hartwig amination": [ |
| 9197, |
| 8830, |
| 4304, |
| 9577, |
| 7019 |
| ], |
| "Darzens bromination": [ |
| 74, |
| 51, |
| 46, |
| 28, |
| 17 |
| ], |
| "Iodination": [ |
| 2087, |
| 2021, |
| 372, |
| 3095, |
| 192 |
| ], |
| "Methyl esterification": [ |
| 1796, |
| 2504, |
| 2621, |
| 6916, |
| 1040 |
| ], |
| "Iodo Sonogashira coupling": [ |
| 3152, |
| 3126, |
| 3834, |
| 2059, |
| 94 |
| ], |
| "Ketone to alcohol reduction": [ |
| 11145, |
| 1876, |
| 11169, |
| 8797, |
| 4371 |
| ], |
| "Iodo N-methylation": [ |
| 12592, |
| 10501, |
| 5573, |
| 1827, |
| 4808 |
| ], |
| "Aldehyde Dess-Martin oxidation": [ |
| 3561, |
| 1295, |
| 3716, |
| 26, |
| 2157 |
| ], |
| "Ketone reductive amination": [ |
| 8201, |
| 2927, |
| 8317, |
| 1743, |
| 10244 |
| ], |
| "Keto alpha-alkylation": [ |
| 2444, |
| 4158, |
| 4988, |
| 1629, |
| 1252 |
| ], |
| "Triflyloxy Miyaura boration": [ |
| 191, |
| 390, |
| 82, |
| 276, |
| 398 |
| ], |
| "Chlorination": [ |
| 4, |
| 2655, |
| 4002, |
| 159, |
| 916 |
| ], |
| "Chloro Miyaura boration": [ |
| 371, |
| 314, |
| 245, |
| 59, |
| 246 |
| ], |
| "Ester hydrolysis": [ |
| 1798, |
| 1161, |
| 161, |
| 175, |
| 1498 |
| ], |
| "O-TBDPS deprotection": [ |
| 995, |
| 1671, |
| 141, |
| 2002, |
| 1557 |
| ], |
| "Grignard ester substitution": [ |
| 136, |
| 32, |
| 121, |
| 140, |
| 42 |
| ], |
| "Bromo Suzuki coupling": [ |
| 8685, |
| 17290, |
| 19876, |
| 13865, |
| 6940 |
| ], |
| "Iodo Stille reaction": [ |
| 138, |
| 176, |
| 51, |
| 182, |
| 79 |
| ], |
| "Bromo Sonogashira coupling": [ |
| 3268, |
| 3059, |
| 3588, |
| 4239, |
| 3698 |
| ], |
| "O-Bn deprotection": [ |
| 495, |
| 1015, |
| 920, |
| 262, |
| 1384 |
| ], |
| "Chloro Sonogashira coupling": [ |
| 21, |
| 235, |
| 225, |
| 7, |
| 72 |
| ], |
| "Alcohol + amine condensation": [ |
| 1449, |
| 1292, |
| 120, |
| 468, |
| 138 |
| ], |
| "O-TBS deprotection": [ |
| 7417, |
| 257, |
| 7042, |
| 2706, |
| 580 |
| ], |
| "Mitsunobu aryl ether synthesis": [ |
| 8423, |
| 3899, |
| 4562, |
| 10960, |
| 7953 |
| ], |
| "Chloro Buchwald-Hartwig amination": [ |
| 3510, |
| 2167, |
| 7744, |
| 3981, |
| 7749 |
| ], |
| "Weinreb amide synthesis": [ |
| 3307, |
| 1667, |
| 779, |
| 386, |
| 397 |
| ], |
| "Iodo Grignard reaction": [ |
| 168, |
| 110, |
| 90, |
| 108, |
| 105 |
| ], |
| "Bromo Miyaura boration": [ |
| 7651, |
| 887, |
| 1612, |
| 993, |
| 6596 |
| ], |
| "Bromo Stille reaction": [ |
| 745, |
| 347, |
| 819, |
| 111, |
| 254 |
| ], |
| "Chloro Suzuki coupling": [ |
| 3139, |
| 3116, |
| 8786, |
| 7350, |
| 2296 |
| ], |
| "Carboxylic acid + amine condensation": [ |
| 110593, |
| 48100, |
| 73018, |
| 121275, |
| 65485 |
| ], |
| "Darzens chlorination": [ |
| 617, |
| 3630, |
| 4508, |
| 802, |
| 414 |
| ], |
| "Wohl-Ziegler bromination": [ |
| 333, |
| 276, |
| 7, |
| 47, |
| 121 |
| ], |
| "Esterification": [ |
| 1362, |
| 3329, |
| 3978, |
| 3943, |
| 1751 |
| ], |
| "Mitsunobu ester synthesis": [ |
| 410, |
| 60, |
| 168, |
| 388, |
| 2 |
| ], |
| "Bromo Grignard preparation": [ |
| 99, |
| 67, |
| 200, |
| 116, |
| 73 |
| ], |
| "O-TIPS deprotection": [ |
| 433, |
| 569, |
| 498, |
| 158, |
| 194 |
| ], |
| "N-Cbz protection": [ |
| 1215, |
| 891, |
| 3967, |
| 239, |
| 2372 |
| ], |
| "Bechamp reduction": [ |
| 8883, |
| 998, |
| 5138, |
| 936, |
| 821 |
| ], |
| "Bromo N-alkylation": [ |
| 38284, |
| 31246, |
| 32954, |
| 60252, |
| 55883 |
| ], |
| "Isocyanate + alcohol reaction": [ |
| 2175, |
| 644, |
| 232, |
| 2080, |
| 328 |
| ], |
| "Carboxylic ester + amine reaction": [ |
| 6089, |
| 2245, |
| 19498, |
| 2226, |
| 7707 |
| ], |
| "Mitsunobu imide reaction": [ |
| 826, |
| 245, |
| 1166, |
| 504, |
| 1185 |
| ], |
| "Carboxy to carbamoyl": [ |
| 4870, |
| 325, |
| 5073, |
| 671, |
| 3434 |
| ], |
| "Claisen-Schmidt condensation": [ |
| 2692, |
| 2390, |
| 2315, |
| 2141, |
| 1295 |
| ], |
| "Amide Schotten-Baumann": [ |
| 17089, |
| 13386, |
| 43891, |
| 46936, |
| 20590 |
| ], |
| "Carbamate Schotten-Baumann": [ |
| 3910, |
| 4351, |
| 6484, |
| 2144, |
| 11004 |
| ], |
| "Chloro Stille reaction": [ |
| 330, |
| 153, |
| 234, |
| 161, |
| 37 |
| ], |
| "Mesyloxy N-alkylation": [ |
| 76, |
| 3754, |
| 5088, |
| 4612, |
| 819 |
| ], |
| "Methoxy to hydroxy": [ |
| 600, |
| 4404, |
| 1746, |
| 4144, |
| 2172 |
| ], |
| "Knoevenagel condensation": [ |
| 271, |
| 1911, |
| 714, |
| 1804, |
| 140 |
| ], |
| "Ester to alcohol reduction": [ |
| 14405, |
| 4002, |
| 6054, |
| 4669, |
| 2584 |
| ], |
| "Wittig olefination": [ |
| 3589, |
| 6830, |
| 4450, |
| 5763, |
| 2478 |
| ], |
| "Steglich esterification": [ |
| 2505, |
| 3305, |
| 2678, |
| 2166, |
| 32 |
| ], |
| "Aldehyde reductive amination": [ |
| 21884, |
| 26774, |
| 18173, |
| 9810, |
| 30531 |
| ], |
| "Chloro N-alkylation": [ |
| 6788, |
| 8800, |
| 17332, |
| 7564, |
| 7014 |
| ], |
| "Chloro Grignard reaction": [ |
| 1133, |
| 318, |
| 557, |
| 577, |
| 1238 |
| ], |
| "Williamson ether synthesis": [ |
| 107, |
| 367, |
| 175, |
| 104, |
| 351 |
| ], |
| "Iodo Buchwald-Hartwig amination": [ |
| 540, |
| 1035, |
| 1000, |
| 514, |
| 104 |
| ], |
| "Iodo Suzuki coupling": [ |
| 756, |
| 3469, |
| 2266, |
| 361, |
| 29 |
| ], |
| "N-Boc protection": [ |
| 10929, |
| 4286, |
| 8583, |
| 5294, |
| 14478 |
| ], |
| "N-Boc deprotection": [ |
| 72309, |
| 92493, |
| 56057, |
| 73519, |
| 1267 |
| ] |
| } |
