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chrom
string
pos
int64
ref
string
alt
string
label
int64
CADD
float64
phyloP-100v
float64
phyloP-241m
float64
phastCons-100v
float64
GPN-MSA
float32
NT
float64
NT-v2
float64
HyenaDNA
float32
Evo2-1B
float64
Evo2-7B
float64
GENERator-1B
float64
GENERator-3B
float64
GENERator-v2-1B
float64
GENERator-v2-3B
float64
1
69,511
A
G
0
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-4.694194
-2.464122
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1
953,279
T
C
0
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G
C
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973,929
T
C
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C
G
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C
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G
A
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G
C
1
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G
A
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A
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T
C
0
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G
A
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A
C
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G
A
0
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1,212,042
C
T
0
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1
1,212,898
C
T
0
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1,213,738
G
A
1
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1
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A
G
1
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1
1,232,280
T
C
1
2.745302
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G
A
1
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1
1,232,471
A
G
1
2.945049
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1
1,232,478
C
T
1
3.931606
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1
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G
A
1
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1
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1
1,232,754
C
A
1
4.121125
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1
1,232,800
G
C
0
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1
1,232,834
T
C
1
4.516843
3.777
3.569
1
7.078125
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1
1,232,896
C
G
1
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1
1,232,897
G
C
1
4.542989
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1
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1
1,232,927
G
A
1
4.493109
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0
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1
1,233,044
C
T
1
4.400743
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1
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1
1,233,177
G
C
1
4.25814
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1
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8.733045
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10.721902
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10.594989
1
1,233,203
T
A
1
3.938952
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1
8.8125
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7.855516
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1
1,243,102
A
G
0
1.275063
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G
A
0
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1
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C
G
0
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1
1,285,621
A
G
0
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1
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G
C
0
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G
A
0
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G
A
0
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C
T
1
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G
A
1
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G
A
0
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G
A
1
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C
T
1
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C
A
1
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G
A
0
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G
A
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C
A
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C
T
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A
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C
T
0
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A
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T
G
1
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A
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T
G
1
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G
A
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A
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T
C
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T
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C
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C
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8.845664
13.063226
10.637304
12.680113
10.869285
1
1,806,514
A
T
1
3.207073
2.553
-1.389
1
9.609375
2.066875
2.518185
-0
9.046723
8.532066
13.651877
11.124712
12.070015
10.546722
1
1,806,515
T
C
1
4.491082
7.815
5.859
1
11.578125
3.729162
4.305667
0.000001
8.921301
8.063851
12.797464
11.192427
12.523984
12.027575
1
1,815,796
G
C
1
1.810245
-0.022
0.045
0.933
8.492188
0.129889
0.150908
-0.000002
4.575043
8.139518
12.744521
8.933823
10.626151
10.952718
1
1,916,540
T
C
0
1.204282
-0.175
-1.396
0
-2.607422
-1.156277
-1.685189
0
-5.322034
-5.989702
-5.261201
-7.359232
-5.373526
-6.650831
1
1,918,090
A
G
0
0.828084
1.22
0.809
0.013
3.164063
0.653571
0.434833
-0.000001
1.469493
3.368572
2.147663
4.615465
3.810565
4.863924
1
1,918,091
T
C
0
0.067017
-0.082
-0.16
0.001
2.382813
-0.823844
-0.971521
-0.000001
0.170221
2.232852
3.770611
4.006744
3.056837
4.361003
1
1,918,484
C
A
0
0.529345
-0.094
-0.465
0.014
2.439453
0.745362
0.920779
-0.000001
1.5949
1.318548
1.276761
5.03856
1.617617
4.373536
1
1,923,107
C
T
0
2.031239
0.55
5.883
0.438
3.990234
0.194937
0.242315
-0.000003
2.3892
5.47671
3.979481
6.004083
3.529667
5.201937
1
1,923,833
C
G
1
3.512015
2.846
8.659
1
7.753906
-0.196059
0.020362
0
5.735404
5.990971
6.877297
6.706469
5.194876
6.077383
1
1,927,024
C
T
1
0.783969
0.382
0.03
0
1.996094
0.378825
0.270885
0.000002
1.096279
2.139229
3.595587
2.430351
3.766405
1.018811
1
1,927,692
C
T
0
-1.649318
-3.588
-5.924
0
-0.583008
-0.025471
0.046523
-0
0.641412
-0.504747
0.198315
1.137317
-0.105217
0.758907
1
1,927,737
T
C
0
0.435867
-0.144
3.951
0
-1.25293
-0.551825
-0.595555
0
-0.61533
-0.898816
-1.002217
-0.132375
-0.776046
-2.621941
1
1,930,143
C
T
0
3.552757
3.98
6.968
1
6.273438
0.25559
0.545018
-0.000002
5.057544
6.089229
3.504193
6.471041
6.050732
5.810993
1
1,942,086
T
C
0
1.532497
2.516
1.494
0.999
-3.904297
-0.125047
-0.336852
0
-2.138956
1.322391
-5.997955
-2.457267
-5.342058
-1.975613
1
1,944,419
C
G
0
2.364683
1.874
4.094
0.939
7.394531
-0.410565
-0.383748
-0.000004
4.469774
4.34293
6.236044
6.269704
5.755176
6.10647
1
1,968,793
T
C
0
-0.478732
0.054
0.904
0.001
-2.328125
0.331844
0.760876
-0
0.693147
0.276094
-1.694331
-0.408094
-1.776515
-0.537003
1
1,970,722
C
T
1
3.017338
3.879
8.484
0.98
6.839844
-0.757549
-0.503136
-0
-0.591364
-3.304095
4.59937
3.922136
4.443548
2.947781
1
1,974,047
G
A
1
0.650387
-1.589
-0.894
0
0.416016
1.782265
0.490918
-0
0.047402
2.128431
4.841298
2.747596
4.379221
1.032501
1
2,025,598
T
C
0
1.082832
-1.217
0.193
0
-3.611328
-3.545675
-3.586224
0.000001
-3.741761
-3.490737
-4.20991
-4.325091
-3.763447
-3.886728
1
2,029,197
C
G
1
3.146233
2.655
5.777
1
9.546875
-0.056515
4.209748
-0.000006
7.777823
8.238629
9.081068
7.677629
8.121512
7.423055
1
2,029,235
C
T
0
0.219853
-0.476
-1.463
0.112
0.580078
0.574805
3.325427
-0.000001
2.872455
3.960751
1.841202
2.293186
3.682693
0.81415
1
2,193,733
G
A
0
0.285874
-0.118
0.297
0
1.341797
1.296382
1.07931
-0.000001
0.92587
2.161359
0.987351
2.121108
0.953787
1.873307
1
2,228,825
C
T
1
3.865474
6.406
5.785
1
7.746094
-0.857549
-0.779931
-0.000002
4.938682
4.904568
5.901509
6.513581
6.689042
7.955806
1
2,228,828
T
G
1
3.488515
4.895
3.829
1
10.546875
1.431248
1.491518
0.000001
8.872511
7.401475
11.123493
9.920112
10.833296
8.392279
1
2,228,848
T
A
1
2.8778
1.305
3.824
1
7.722656
-0.34151
-0.390475
0
5.647832
3.35451
11.133122
7.351341
10.475573
7.54264
End of preview. Expand in Data Studio

Updates

[2025-09-09] We have added ClinVar variant effect prediction results to the repository. The evaluation dataset was sourced from SongLab. The benchmark includes comparisons of GENERator against Evo2, NT, NT-v2, HyenaDNA, GPN-MSA, CADD, phyloP, and phastCons.

Abouts

The human reference genome data is sourced from the NCBI website.

We have applied minor formatting adjustments to the dataset to facilitate streamlined data analysis.

How to use

from datasets import load_dataset

datasets = load_dataset("GenerTeam/variant-effect-prediction")
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