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HIV-V-SMILES

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You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(C)(C)CC(C)(C)c1cc2c(O)c(c1)Cc1cc(C(C)(C)CC(C)(C)C)cc(c1O)Cc1cc(C(C)(C)CC(C)(C)C)cc(c1O)Cc1cc(C(C)(C)CC(C)(C)C)cc(c1O)Cc1cc(C(C)(C)CC(C)(C)C)cc(c1O)C2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(CNc1ccc2c(=S)c3ccccc3[nH]c2c1)Nc1ccccc1-c1ccccc1NC(=O)CNc1ccc2c(=S)c3ccccc3[nH]c2c1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cc1nc(NN=Cc2ccccc2Cl)nc(O)c1CCO Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CN(C(=O)c1ccco1)C(=S)N1CCN(c2ccccn2)CC1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC1=C(C#N)C(=O)OC1(C)C(CC(=O)c1ccccc1)c1ccccc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC1CC(CC(C)=O)CN(C#N)CCc2c1[nH]c1ccccc21 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC(=O)C1(NC(=O)C(N)CC(=O)O)C(C)C1C Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(CNc1ccc(Cl)cc1)(CNc1ccc(Cl)cc1)[N+](=O)[O-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cl.NCCNCCNCc1c2ccccc2c(CNCCNCCN)c2ccccc12 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=S(=O)(O)c1ccc(N=Nc2cc(S(=O)(=O)O)c3ccccc3c2O)c2ccccc12 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CN1C2CCC1CC1(C2)SCCS1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=c1[nH]c(=O)n(C2CC(O)C(CO)C2)cc1I Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cn1cnc2ncnc-2c1N Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccccc1C1=Nc2ccccc2N=C(c2ccccc2O)C1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccc(C=CC(=O)C(C)C)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCC1CCC2C(CCC3(C)C(OC(C)=O)CCC23)C1C(=O)OC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CSc1n[n+](C)cc(N)c1N.[I-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C1NCN(c2ccccc2)C12CCN(CCCSc1ccc(F)cc1)CC2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(C)C(=Nc1ccc(Cl)c(Cl)c1)N(C)C Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=P(c1ccccc1)(c1ccccc1)c1ccc2c(c1)OCCOCCOCCOCCO2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=O)Nc1ccc2c(c1)nc1c3ccccc3ccn21 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCC(C)c1c(NS(=O)(=O)c2ccc(C)cc2)o[nH]c1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)c1nc2c(C)nc(N(C)C)nc2n(C)c1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC(=O)CCSC=CC(=O)O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCC12C=CCN3CCC4(C(=C(C(=O)OC)C1Nc1ncnc5c1ncn5C1OC(COC(C)=O)C(OC(C)=O)C1OC(C)=O)Nc1ccccc14)C32 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1cc2c(cc1OC)-c1cc3ccccc3c(=O)n1CC2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C1C(=Cc2ccccc2)CN(C(=O)C=Cc2ccccc2)CC1=Cc1ccccc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCCCCC1C2C(=O)NC(=O)C1C(=O)NC2=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC12OCCN(CCO)C1=CC(=O)C1(C)N=NC(C)C12 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CNC(=O)c1nn[nH]c1O.[NaH] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=O)c1ccc(NC(=O)C(=O)C(C#N)CC(C)(C)C=O)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: C[N+](C)(C)CC(CC(=O)[O-])C1CC1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)c1ccc(-n2nc(C)cc(Cl)c2=O)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCCCCCCCCCCCCCCCCCSCC(C)(COP(=O)(O)OP(=O)(O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1N=[N+]=[N-])OC(=O)CCCCCCCCCCCCCCC.[NaH] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(c1ccco1)N(C(=S)N1CCN(c2ccccc2)CC1)C1CCCCC1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Nc1ncnc2c1ncn2C1CC(CO)C(CO)O1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C1CC2C(CN(OCc3ccccc3)C2COC(=O)c2ccccc2)O1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: ClC1=NN=C(c2c[nH]c3ccccc23)CC1NCc1ccccc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccc(C(=O)CCN(C)C)cc1.Cl Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC(=O)Cc1c(-c2[nH]c3ccccc3c2CC(=O)OC)[nH]c2ccccc12 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC12CCC3C(CCC4=CC(=O)CCC43C)C1Cc1cnn(-c3ccccc3)c1N2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CSCCC(N)C(=O)NCCS(=O)(=O)O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CNc1c(Cl)cccc1S(=O)(=O)c1ccccc1[N+](=O)[O-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cc1ccc(NC(=O)C(CC2Nc3c(ccc4c3C(=O)c3ccccc3C4=O)NC2O)=NNC(C)(C)C)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)c1nc(C)c(-c2ccccc2)c(-c2ccccc2)c1C Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(CNC(=O)c1ccccc1)(CNC(=O)c1ccccc1)[N+](=O)[O-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)NC(Nc1ccc(C(=O)O)cc1)(C(F)(F)F)C(F)(F)F Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC1(C)COC(c2cccc(C3=NC(C)(C)CO3)c2)=N1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=S)NC=C1C(=O)NC(=O)NC1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=NNC(=S)Nc1cccc(C)c1)c1ccccn1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCCCOC(=O)NC(Nc1cccc(C(F)(F)F)c1)(C(F)(F)F)C(F)(F)F Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CSc1c(C#N)c(O)n(-c2ccc(Cl)cc2)c(=O)c1C(C)=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccccc1NC(=S)Nc1cccc(C)n1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCP(=O)(CC)C(Cl)(Cl)C(=O)NC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Clc1ccc(OCc2nnc3n2N=C(c2ccc(Br)cc2)CS3)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCN(CC)c1c(-c2c(OC(C)C)c(=O)c2=O)c(=O)n2ccsc2c1OC(C)=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CN(C)CCOC1(Cc2ccc(F)cc2)CCC(C(C)(C)C)CC1.O=C(O)C=CC(=O)O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCC12C=CCN3CCC4(c5cc(C6(C(=O)OC)CC7CN(CCc8c6[nH]c6ccccc86)CC6CCCCC67)c(OC)cc5N(C)C4C(O)(C(=O)OC)C1OC(C)=O)C32.COS(=O)(=O)O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: NNc1ncnc2cccc(Cl)c12 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1cccc(C=C2Sc3scc(-c4ccccc4)[n+]3C2=O)c1O.[Cl-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCc1cccc(C(C)CC)c1NC(=O)CC1C(=O)Nc2ccccc2S1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CN(N=Cc1ccnc2ccccc12)c1c([N+](=O)[O-])cc([N+](=O)[O-])cc1[N+](=O)[O-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccc(C=CC(=O)c2ccccc2)cc1OC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(CCC(CC(=O)c1ccc(Cl)cc1)=NO)Nc1cccc(Cl)c1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC1(C)OC2OC(CO)C(OS(C)(=O)=O)C2O1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC=CC=Cc1nc(C#N)c(N)o1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COC1c2ccccc2C2C(Cl)(Cl)C23c2ccccc2C13 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cc1cc(N=Nc2c(C)ccc3ncccc23)ccc1N Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: N=C1NN(c2ccccc2)C(=O)C1C(=O)C(=O)Nc1ccc(Cl)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(Nc1ccccc1)n1cc(-c2ccccn2)c(N2CCOCC2)n1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=O)N(C(C)=O)c1c(C)cc(-c2ccccc2)oc1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)C=Cc1ccccc1Cl Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)NC(=S)N(C)P(=S)(OCC)N(C)C(=S)NC(=O)OCC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC(=O)[O-].COc1ccc(-[n+]2nc(S(=O)(=O)O)c(C=Cc3ccc(N(C)C)cc3)cc2C#N)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(Nc1ccc(O)cc1)C(Cl)(Cl)Cl Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cl.O=C(OCCN1CCCCC1)C(c1ccccc1)C1(O)CCSCC1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cn1c2c(c3ccccc31)CCN(CCN1CCN(c3ccccc3)CC1)C2=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1cc(OC)c2c(-c3ccc(O)cc3)cc(=O)oc2c1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC1CCOS(=O)O1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Cn1cc[n+]([Pt-2]2([n+]3ccn(C)c3)[n+]3ccccc3-c3cccc[n+]32)c1.[O-][Cl+3]([O-])([O-])[O-] Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCN(CC)CCC12CC(C)OC1=Nc1ccccc1NC2=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCCCSCCC(N)P(=O)(O)O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccc(C=NC23CC4CC(CC(C4)C2)C3)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)N1C2c3ccccc3C(c3ccccc32)N1C(=O)OCC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=S(c1ccccc1O)S(=O)c1ccccc1O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: Nc1cccc(N=Nc2c(S(=O)(=O)O)cc3cc(NC(=O)Nc4ccc5c(O)c(N=Nc6cccc(N)c6)c(S(=O)(=O)O)cc5c4)ccc3c2O)c1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

Yes

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: OCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(Nc1sccc1S(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)NC(CCC(N)=O)C(=O)O.N Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1nc2c(c(=O)n1C)NC1C(N2)OCC(O)C1O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: c1cc2sc1CSCCSCCSC2 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(O)CC1CCCCC12CCOC2=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CC1(C)OC(=O)C(C#N)=C1C=Cc1coc2ccc(Cl)cc2c1=O Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CC1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(Nc1ccc(Cl)cc1Cl)c1cc(=NO)c2ccc(O)cc2o1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: COc1ccc(OC)c(C(Nc2ccc3cn[nH]c3c2)P(=O)(c2ccccc2)c2ccccc2)c1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: O=C(O)CCCCC1CCSS1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)c1cc2c(C(=O)c3ccc([N+](=O)[O-])cc3)c(C(C)=O)ccc2[nH]1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: N#CC=Cc1ccc(F)cc1 Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No

You are an expert chemist, your task is to predict the property of molecule using your experienced chemical property prediction knowledge. Please strictly follow the format, no other information can be provided. Given the SMILES string of a molecule, the task focuses on predicting molecular properties, specifically inhibition of HIV replication based on the SMILES string representation of each molecule. You will be provided with several example molecules, each accompanied by a binary label indicating whether a molecule can inhibit (Yes) or cannot inhibit (No) HIV replication. The task is to precisely predict the binary label for a given molecule considering its properties and its potential to impede HIV replication. Please answer with only Yes or No for binary label. SMILES: O=C(C=Cc1ccc(O)c(O)c1)OCc1ccccc1 Inhibit: Yes SMILES: CCN(Cc1cccc(S(=O)(=O)O)c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)O)c3)C=C2)c2ccccc2)cc1 Inhibit: Yes SMILES: CCCN(CCC)C1CCc2c(ccc3cc[nH]c23)C1 Inhibit: No SMILES: CCC1(N)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 Inhibit: No Below is the molecule whose property you have to predict. Along with is the image structure of the molecule. SMILES: CCOC(=O)C(=Cc1ccc(Br)cc1)C(=O)OCC Inhibit: You have to predict whether it inhibits HIV with answer Yes or No.

No