File size: 7,296 Bytes
fb4710e
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
from datetime import datetime
from dotenv import load_dotenv
from img2table.document import Image
from langchain.chains.combine_documents.map_reduce import MapReduceDocumentsChain
from langchain.chains.combine_documents.reduce import ReduceDocumentsChain
from langchain.chains.combine_documents.stuff import StuffDocumentsChain
from langchain.chains.llm import LLMChain
from langchain.prompts import PromptTemplate
from langchain_openai import ChatOpenAI
from pdf2image import convert_from_path
from prompt import prompt_entity_gsd_chunk, prompt_entity_gsd_combine, prompt_entity_summ_chunk, prompt_entity_summ_combine, prompt_entities_chunk, prompt_entities_combine, prompt_entity_one_chunk, prompt_table
from table_detector import detection_transform, device, model, ocr, outputs_to_objects

import io
import json
import os
import pandas as pd
import re
import torch

load_dotenv()

llm = ChatOpenAI(temperature=0, model_name="gpt-4-0125-preview")
llm_p = ChatOpenAI(temperature=0, api_key=os.environ['PERPLEXITY_API_KEY'], base_url="https://api.perplexity.ai")

prompts = {
    'gsd': [prompt_entity_gsd_chunk, prompt_entity_gsd_combine],
    'summ': [prompt_entity_summ_chunk, prompt_entity_summ_combine],
    'all': [prompt_entities_chunk, prompt_entities_combine]
}

def get_entity(data):

    chunks, types = data

    map_template = prompts[types][0]
    map_prompt = PromptTemplate.from_template(map_template)
    map_chain = LLMChain(llm=llm, prompt=map_prompt)

    reduce_template = prompts[types][1]
    reduce_prompt = PromptTemplate.from_template(reduce_template)
    reduce_chain = LLMChain(llm=llm, prompt=reduce_prompt)

    combine_chain = StuffDocumentsChain(
        llm_chain=reduce_chain, document_variable_name="doc_summaries"
    )

    reduce_documents_chain = ReduceDocumentsChain(
        combine_documents_chain=combine_chain,
        collapse_documents_chain=combine_chain,
        token_max=100000,
    )

    map_reduce_chain = MapReduceDocumentsChain(
        llm_chain=map_chain,
        reduce_documents_chain=reduce_documents_chain,
        document_variable_name="docs",
        return_intermediate_steps=False,
    )

    result = map_reduce_chain.invoke(chunks)['output_text']
    print(types)
    print(result)
    if types != 'summ':
        result = re.findall('(\{[^}]+\})', result)[0]
        return eval(result)
    
    return result

def get_entity_one(chunks):

    result = llm.invoke(prompt_entity_one_chunk.format(chunks)).content

    print('One')
    print(result)
    result = re.findall('(\{[^}]+\})', result)[0]

    return eval(result)

def get_table(path):

    start_time = datetime.now()
    images = convert_from_path(path)
    print('PDF to Image', round((datetime.now().timestamp() - start_time.timestamp()) / 60, 2), "minutes")
    tables = []

    # Loop pages
    for image in images:

        pixel_values = detection_transform(image).unsqueeze(0).to(device)
        with torch.no_grad():
            outputs = model(pixel_values)

        id2label = model.config.id2label
        id2label[len(model.config.id2label)] = "no object"
        detected_tables = outputs_to_objects(outputs, image.size, id2label)

        # Loop table in page (if any)
        for idx in range(len(detected_tables)):
            cropped_table = image.crop(detected_tables[idx]["bbox"])
            if detected_tables[idx]["label"] == 'table rotated':
                cropped_table = cropped_table.rotate(270, expand=True)

            # TODO: what is the perfect threshold?
            if detected_tables[idx]['score'] > 0.9:
                print(detected_tables[idx])
                tables.append(cropped_table)

    print('Detect table from image', round((datetime.now().timestamp() - start_time.timestamp()) / 60, 2), "minutes")
    genes = []
    snps = []
    diseases = []

    # Loop tables
    for table in tables:

        buffer = io.BytesIO()
        table.save(buffer, format='PNG')
        image = Image(buffer)
        
        # Extract to dataframe
        extracted_tables = image.extract_tables(ocr=ocr, implicit_rows=True, borderless_tables=True, min_confidence=0)

        if len(extracted_tables) == 0:
            continue

        # Combine multiple dataframe
        df_table = extracted_tables[0].df
        for extracted_table in extracted_tables[1:]:
            df_table = pd.concat([df_table, extracted_table.df]).reset_index(drop=True)

        df_table.loc[0] = df_table.loc[0].fillna('')

        # Identify multiple rows (in dataframe) as one row (in image)
        rows = []
        indexes = []
        for i in df_table.index:
            if not df_table.loc[i].isna().any():
                if len(indexes) > 0:
                    rows.append(indexes)
                indexes = []
            indexes.append(i)
        rows.append(indexes)

        df_table_cleaned = pd.DataFrame(columns=df_table.columns)
        for row in rows:
            row_str = df_table.loc[row[0]]
            for idx in row[1:]:
                row_str += ' ' + df_table.loc[idx].fillna('')
            row_str = row_str.str.strip()
            df_table_cleaned.loc[len(df_table_cleaned)] = row_str

        # Ask LLM with JSON data
        json_table = df_table_cleaned.to_json(orient='records')
        str_json_table = json.dumps(json.loads(json_table), indent=2)

        result = llm.invoke(prompt_table.format(str_json_table)).content
        print('table')
        print(result)
        result = result[result.find('['):result.rfind(']')+1]
        try:
            result = eval(result)
        except SyntaxError:
            result = []

        for res in result:
            res_gene = res['Genes']
            res_snp = res['SNPs']
            res_disease = res['Diseases']

            for snp in res_snp:
                genes.append(res_gene)
                snps.append(snp)
                diseases.append(res_disease)

    print('OCR table to extract', round((datetime.now().timestamp() - start_time.timestamp()) / 60, 2), "minutes")
    print(genes, snps, diseases)
    
    return genes, snps, diseases

def validate(df):

    df = df.fillna('')
    df['Genes'] = df['Genes'].str.upper()
    df['SNPs'] = df['SNPs'].str.lower()

    # Check if there is two gene names
    sym = ['-', '/', '|']
    for i in df.index:
        gene = df.loc[i, 'Genes']
        for s in sym:
            if s in gene:
                genes = gene.split(s)
                df.loc[len(df)] = df.loc[i]
                df.loc[i, 'Genes'] = genes[0]
                df.loc[len(df) - 1, 'Genes'] = genes[1]

    # Check if there is SNPs without 'rs'
    for i in df.index:
        safe = True
        snp = df.loc[i, 'SNPs']
        if not re.fullmatch('rs(\d)+|', snp):
            if not re.fullmatch('s(\d)+', snp):
                if not re.fullmatch('(\d)+', snp):
                    safe = False
                    df = df.drop(i)
                else:
                    snp = 'rs' + snp
            else:
                snp = 'r' + snp

        if safe:
            df.loc[i, 'SNPs'] = snp

    df.reset_index(drop=True, inplace=True)

    # TODO: How to validate genes and SNPs?

    # TODO: Validate genes and diseases with LLM
    result = llm_p.invoke(model='mistral-7b-instruct', input='How many stars?')

    return df