File size: 16,000 Bytes
af7726d
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
factor	influence_score	influence_score_raw	target_score	target_score_scaled	G_score	G_score_scaled	direct_targets	factor_fc
FOSB	1.0	20372.887953158137	20364.280950899836	0.976	8.607002258300781	0.9478260869565218	8551	8.607002258300781
FOSL1	0.9919354838709677	21196.517633552183	21190.54236518823	1.0	5.975268363952637	0.8869565217391305	9197	5.975268363952637
FOSL2	0.9838709677419355	20151.624214298306	20144.80811942297	0.96	6.816094875335693	0.9217391304347826	8340	6.816094875335693
NR1D1	0.9758064516129032	20285.81821760538	20280.145736068516	0.968	5.672481536865234	0.8608695652173913	8498	5.672481536865234
FOXQ1	0.967741935483871	16640.369857932197	16631.66479792701	0.856	8.705060005187988	0.9565217391304348	5407	8.705060005187988
HES1	0.9596774193548387	20477.103905416767	20472.02960226659	0.984	5.074303150177002	0.8173913043478261	8628	5.074303150177002
ATF3	0.9516129032258064	20956.436678578713	20951.83896558509	0.992	4.597712993621826	0.782608695652174	10762	4.597712993621826
NR4A1	0.9435483870967741	16561.431545611063	16555.269161101023	0.848	6.162384510040283	0.9043478260869566	5490	6.162384510040283
MEIS1	0.9354838709677419	17964.743204734354	17960.07128824952	0.92	4.671916484832764	0.791304347826087	6556	4.671916484832764
FOS	0.9274193548387096	17368.802999830423	17364.085163450418	0.904	4.717836380004883	0.8	8808	4.717836380004883
SMAD3	0.9193548387096774	19810.86716078272	19807.022343144323	0.952	3.844817638397217	0.7304347826086958	8799	3.844817638397217
PAX6	0.9112903225806451	13056.037407042633	13023.672886016022	0.656	32.36452102661133	1.0	2487	32.36452102661133
SNAI2	0.9032258064516129	14126.326903329942	14119.819754587266	0.72	6.507148742675781	0.9130434782608696	3376	6.507148742675781
IRF6	0.8951612903225806	14571.002343377537	14565.551127633518	0.744	5.451215744018555	0.8434782608695652	3845	5.451215744018555
GRHL2	0.8870967741935484	17004.983145477865	17001.518471481893	0.88	3.46467399597168	0.6608695652173914	5700	3.46467399597168
RORC	0.8790322580645161	12507.268530834119	12499.415104854505	0.6	7.853425979614258	0.9391304347826087	2018	7.853425979614258
NFE2L2	0.8709677419354839	18911.59550254352	18909.07611935146	0.9440000000000001	2.519383192062378	0.5565217391304348	7316	2.519383192062378
EHF	0.8629032258064516	12127.095182462643	12113.575751348446	0.496	13.519431114196776	0.991304347826087	1628	13.519431114196776
EGR1	0.8548387096774194	15615.486185811633	15611.817756913775	0.8	3.668428897857666	0.6782608695652175	5952	3.668428897857666
OVOL1	0.8467741935483871	12277.813796358769	12271.78652794904	0.552	6.027268409729004	0.8956521739130435	1768	6.027268409729004
NR4A2	0.8387096774193549	14451.439987663332	14447.650093797747	0.736	3.789893865585327	0.7043478260869566	3808	3.789893865585327
MAF	0.8306451612903225	16096.861494316965	16094.207115425974	0.8240000000000001	2.654378890991211	0.6000000000000001	4975	2.654378890991211
KLF6	0.8225806451612903	17212.14659689284	17209.924743159776	0.896	2.221853733062744	0.49565217391304345	7172	2.221853733062744
KLF3	0.814516129032258	17459.96068855336	17457.97929533532	0.912	1.9813932180404663	0.46956521739130436	8219	1.9813932180404663
RARG	0.8064516129032258	13713.63773857686	13710.474510303467	0.704	3.163228273391724	0.6434782608695653	3042	3.163228273391724
NR1D2	0.7983870967741935	18582.843030535736	18580.929611289062	0.928	1.913419246673584	0.41739130434782606	7033	1.913419246673584
ZBTB7A	0.7903225806451613	14933.413487176836	14930.881865482272	0.76	2.53162169456482	0.5739130434782609	4604	2.53162169456482
CUX1	0.782258064516129	15441.53849651921	15439.1156230222	0.784	2.4228734970092773	0.5391304347826088	4565	2.4228734970092773
KLF5	0.7741935483870968	16921.05056595566	16919.101653692742	0.872	1.948912262916565	0.43478260869565216	8153	1.948912262916565
ELF1	0.7661290322580645	16011.638546738099	16009.422191414307	0.8160000000000001	2.216355323791504	0.48695652173913045	5669	2.216355323791504
KLF4	0.7580645161290323	16388.510568023037	16386.531031012844	0.84	1.979537010192871	0.4608695652173913	7302	1.979537010192871
BHLHE40	0.75	11838.671931120536	11833.312899920127	0.456	5.359031200408936	0.8347826086956522	1280	5.359031200408936
IRF2	0.7419354838709677	12205.575953460348	12201.125885463369	0.512	4.45006799697876	0.773913043478261	1742	4.45006799697876
HIVEP2	0.7338709677419355	12327.45900164385	12323.664857967093	0.56	3.794143676757813	0.7130434782608697	1884	3.794143676757813
ZKSCAN1	0.7258064516129032	15591.685101496932	15589.69085561013	0.792	1.9942458868026731	0.4782608695652174	4476	1.9942458868026731
MAFF	0.717741935483871	10330.853373941693	10323.17012971333	0.336	7.683244228363037	0.9304347826086957	802	7.683244228363037
ELF3	0.7096774193548387	12622.66421297847	12619.679598844636	0.624	2.984614133834839	0.6347826086956523	2049	2.984614133834839
STAT1	0.7016129032258065	16240.870465861562	16238.933569775823	0.832	1.936896085739136	0.4260869565217391	5077	1.936896085739136
ZBTB33	0.6935483870967741	16693.83762897081	16692.023683796593	0.864	1.813945174217224	0.3826086956521739	6244	1.813945174217224
NKX3-1	0.6854838709677419	12049.306495545521	12045.447767851963	0.48	3.8587276935577393	0.7391304347826088	1631	3.8587276935577393
ZNF24	0.6774193548387096	18786.102068295157	18785.40998362509	0.936	0.6920846700668335	0.2434782608695652	7232	0.6920846700668335
HES5	0.6693548387096774	9466.56540176604	9457.270412180163	0.2	9.294989585876465	0.9652173913043479	294	9.294989585876465
ETS2	0.6612903225806451	12846.85942900999	12844.52653373106	0.648	2.332895278930664	0.5130434782608696	2197	2.332895278930664
TP63	0.6532258064516129	9390.125929709446	9380.702275153171	0.184	9.423654556274414	0.9739130434782609	296	9.423654556274414
OSR2	0.6451612903225806	12689.801164137809	12687.499054181068	0.64	2.302109956741333	0.5043478260869566	2199	2.302109956741333
MYC	0.6370967741935484	13593.856439215708	13591.885417205858	0.6880000000000001	1.9710220098495483	0.45217391304347826	2899	1.9710220098495483
MAFB	0.6290322580645161	11890.776717463623	11887.21203831781	0.464	3.5646791458129883	0.6695652173913044	1557	3.5646791458129883
NFKB1	0.6209677419354839	12124.979935602949	12122.032523112104	0.504	2.9474124908447266	0.6173913043478262	1697	2.9474124908447266
IRF1	0.6129032258064516	12085.95316971872	12082.994850293137	0.488	2.9583194255828857	0.6260869565217392	1936	2.9583194255828857
EGR3	0.6048387096774194	10582.628351277885	10578.2604261108	0.344	4.36792516708374	0.7652173913043478	983	4.36792516708374
ETV6	0.5967741935483871	14280.948301927872	14279.175697700806	0.728	1.77260422706604	0.3739130434782609	3463	1.77260422706604
FOXA1	0.5887096774193549	9947.763239968624	9942.807845700589	0.288	4.955394268035889	0.8086956521739131	600	4.955394268035889
FOXC1	0.5806451612903226	12241.991968581595	12239.602819869437	0.544	2.389148712158203	0.5304347826086957	1797	2.389148712158203
NR3C1	0.5725806451612903	14721.204984471167	14719.949259564246	0.752	1.2557249069213867	0.3217391304347826	4278	1.2557249069213867
ASCL2	0.564516129032258	13132.573691056405	13130.759162471924	0.672	1.8145285844802856	0.391304347826087	2513	1.8145285844802856
AHR	0.5564516129032258	9636.429228579385	9631.271456515176	0.23199999999999998	5.157772064208984	0.8260869565217392	404	5.157772064208984
ARNTL	0.5483870967741935	11780.129382641966	11777.376685889418	0.448	2.7526967525482178	0.6086956521739131	1340	2.7526967525482178
BHLHE41	0.5403225806451613	9286.432622698307	9280.751999643802	0.16	5.6806230545043945	0.8695652173913044	234	5.6806230545043945
HLF	0.532258064516129	8081.744454450985	8070.847499914547	0.04	10.896954536437988	0.982608695652174	43	10.896954536437988
SMAD2	0.5241935483870968	15913.809409832025	15913.297005330587	0.808	0.5124045014381409	0.20869565217391303	5915	0.5124045014381409
JUN	0.5161290322580645	9802.807450994474	9798.589393362028	0.264	4.218057632446289	0.7478260869565218	506	4.218057632446289
JUNB	0.5080645161290323	9969.04536595242	9965.33244671719	0.304	3.712919235229492	0.6956521739130436	562	3.712919235229492
ETV2	0.5	9680.706161861699	9676.883085851949	0.24	3.823076009750366	0.7217391304347827	348	3.823076009750366
RXRA	0.49193548387096775	12235.942282314449	12234.09289598003	0.528	1.8493863344192505	0.40869565217391307	1937	1.8493863344192505
KLF2	0.4838709677419355	15112.187523081357	15111.786580636555	0.768	0.4009424448013305	0.16521739130434782	4713	0.4009424448013305
TGIF1	0.47580645161290325	17203.194420550833	17203.056196649442	0.888	0.1382239013910293	0.04347826086956522	6384	0.1382239013910293
ZBTB7B	0.46774193548387094	10670.488008317057	10667.967920359675	0.36	2.520087957382202	0.5652173913043479	650	2.520087957382202
ELK4	0.4596774193548387	12365.327413757665	12363.906955083234	0.576	1.4204586744308472	0.3391304347826087	1801	1.4204586744308472
IKZF2	0.45161290322580644	7663.60463097237	7657.699969316944	0.032	5.904661655426025	0.8782608695652174	23	5.904661655426025
SP3	0.4435483870967742	13680.518285004815	13680.048388420066	0.696	0.4698965847492218	0.2	2693	0.4698965847492218
FOXN3	0.43548387096774194	12558.122937526308	12557.187026943766	0.616	0.9359105825424194	0.26956521739130435	1692	0.9359105825424194
ATF4	0.4274193548387097	15177.986846401944	15177.718597367062	0.776	0.2682490348815918	0.10434782608695652	4306	0.2682490348815918
TFAP2A	0.41935483870967744	819.3433444707309	813.692679664365	0.008	5.650664806365967	0.8521739130434783	6	5.650664806365967
ELK3	0.41129032258064513	11135.651283377816	11133.701029295136	0.4	1.9502540826797483	0.4434782608695652	941	1.9502540826797483
MXI1	0.4032258064516129	8841.610278935912	8837.291846604827	0.07999999999999999	4.318432331085205	0.7565217391304349	146	4.318432331085205
CREB3L2	0.3951612903225806	11647.308816845785	11645.484324152838	0.432	1.824492692947388	0.4	1634	1.824492692947388
ZNF652	0.3870967741935484	13897.820437554092	13897.567410502405	0.712	0.2530270516872406	0.09565217391304348	3409	0.2530270516872406
ZBTB47	0.3790322580645161	9203.018463288345	9199.700863753356	0.144	3.3175995349884038	0.6521739130434783	228	3.3175995349884038
CEBPG	0.3709677419354839	13105.923285513953	13105.647292136982	0.664	0.2759933769702911	0.11304347826086956	2611	0.2759933769702911
HBP1	0.3629032258064516	9412.19266703132	9409.647375369104	0.192	2.5452916622161865	0.582608695652174	262	2.5452916622161865
JUND	0.3548387096774194	12034.001356810246	12032.888151854191	0.472	1.1132049560546875	0.28695652173913044	1732	1.1132049560546875
CREB5	0.3467741935483871	12399.379242349802	12398.939384628473	0.584	0.4398577213287353	0.17391304347826086	2012	0.4398577213287353
SOX9	0.3387096774193548	8141.193508607512	8137.510741216307	0.048	3.682767391204834	0.6869565217391305	35	3.682767391204834
STAT2	0.33064516129032256	12630.842544782416	12630.616104546443	0.632	0.2264402359724044	0.08695652173913043	2062	0.2264402359724044
HIVEP1	0.3225806451612903	11774.871195354766	11773.762370386428	0.44	1.1088249683380127	0.2782608695652174	1428	1.1088249683380127
NFE2L1	0.31451612903225806	13135.06491998564	13134.950372859645	0.68	0.1145471259951591	0.034782608695652174	2587	0.1145471259951591
REL	0.3064516129032258	10211.478239146529	10209.862205592452	0.32	1.6160335540771484	0.3565217391304348	677	1.6160335540771484
CEBPB	0.29838709677419356	10598.229052005143	10596.982763705582	0.352	1.2462882995605469	0.3130434782608696	828	1.2462882995605469
RFX5	0.2903225806451613	12216.664917041173	12216.315432448497	0.52	0.3494845926761627	0.1391304347826087	1682	0.3494845926761627
SOX15	0.282258064516129	11055.742749474082	11054.887590787444	0.384	0.8551586866378784	0.2608695652173913	787	0.8551586866378784
PBX2	0.27419354838709675	12486.759918052087	12486.620412814746	0.592	0.1395052373409271	0.052173913043478265	2298	0.1395052373409271
MAFK	0.2661290322580645	8922.01485800654	8919.564351319375	0.088	2.450506687164306	0.5478260869565218	140	2.450506687164306
NR2F2	0.25806451612903225	8994.961794341647	8992.58021136626	0.11199999999999999	2.381582975387573	0.5217391304347827	149	2.381582975387573
ETV5	0.25	2568.5240172244867	2565.9709707595666	0.024	2.553046464920044	0.591304347826087	25	2.553046464920044
MTF1	0.24193548387096775	12531.936686998815	12531.936686998815	0.608	0.0	0.0	2051	0.5452552437782288
FOXP1	0.2338709677419355	10966.060098934133	10965.536469507177	0.376	0.5236294269561768	0.21739130434782608	957	0.5236294269561768
FOXK1	0.22580645161290322	11133.094333575384	11132.625442312376	0.392	0.4688912630081177	0.19130434782608696	653	0.4688912630081177
ETV3	0.21774193548387097	9836.96820548821	9835.776334918028	0.272	1.1918705701828003	0.30434782608695654	447	1.1918705701828003
MAX	0.20967741935483872	12328.513028897563	12328.513028897563	0.5680000000000001	0.0	0.0	1415	0.1332650035619735
RUNX1	0.20161290322580644	12236.945648523031	12236.84108188188	0.536	0.104566641151905	0.026086956521739132	1776	0.104566641151905
RARA	0.1935483870967742	9042.464255023195	9040.8464760067	0.12	1.617779016494751	0.3652173913043478	178	1.617779016494751
HES4	0.18548387096774194	9794.920739665073	9794.37647940163	0.256	0.5442602634429932	0.22608695652173913	618	0.5442602634429932
MEF2A	0.1774193548387097	9855.874243320057	9855.420488626787	0.28	0.4537546932697296	0.1826086956521739	544	0.4537546932697296
ATF6	0.16935483870967744	9066.376875083406	9064.985608260591	0.128	1.3912668228149414	0.33043478260869563	185	1.3912668228149414
TCF7L1	0.16935483870967744	10288.145607858332	10287.859384655389	0.328	0.2862232029438019	0.13043478260869565	778	0.2862232029438019
BBX	0.16129032258064516	8973.556227092324	8972.10594356495	0.10400000000000001	1.4502835273742676	0.34782608695652173	148	1.4502835273742676
STAT3	0.1532258064516129	9492.427333728052	9491.73715515492	0.208	0.6901785731315613	0.23478260869565218	282	0.6901785731315613
ZNF768	0.14516129032258066	11583.836729313252	11583.788727003155	0.424	0.0480023100972175	0.01739130434782609	1263	0.0480023100972175
MYPOP	0.13709677419354838	9955.452277563461	9955.167713843235	0.296	0.2845637202262878	0.1217391304347826	394	0.2845637202262878
RFX2	0.12903225806451613	11467.005377397109	11467.005377397109	0.416	0.0	0.0	1156	1.2413601875305176
FOXJ3	0.12096774193548387	11300.215614383971	11300.215614383971	0.40800000000000003	0.0	0.0	849	0.7743796110153198
PPARD	0.11290322580645162	8956.835701906968	8955.716085398484	0.096	1.1196165084838867	0.2956521739130435	104	1.1196165084838867
FOXJ2	0.10483870967741934	9536.43415180546	9536.080515689671	0.224	0.3536361157894134	0.14782608695652175	382	0.3536361157894134
ZNF784	0.0967741935483871	10715.623067426455	10715.623067426455	0.368	0.0	0.0	1009	0.5689424872398376
ZFX	0.08870967741935484	9715.57830483135	9715.373475987875	0.248	0.2048288434743881	0.07826086956521738	277	0.2048288434743881
RFX7	0.08064516129032259	9973.319302195405	9973.319302195405	0.312	0.0	0.0	518	0.7982768416404724
TCF7L2	0.07258064516129031	8207.606399353203	8206.75229352301	0.056	0.8541058301925659	0.25217391304347825	55	0.8541058301925659
CREB3	0.06451612903225806	9507.374572410652	9507.17574785597	0.216	0.1988245546817779	0.06956521739130435	330	0.1988245546817779
ZNF219	0.056451612903225805	8617.948887554541	8617.573283103839	0.07200000000000001	0.3756044507026672	0.15652173913043477	85	0.3756044507026672
RFX3	0.04838709677419355	9359.930452937617	9359.930452937617	0.176	0.0	0.0	260	1.1874786615371704
ZNF524	0.04032258064516129	9327.358261129031	9327.358261129031	0.16799999999999998	0.0	0.0	202	0.7021344900131226
MEF2D	0.03225806451612903	9229.895723460364	9229.895723460364	0.152	0.0	0.0	277	0.7373666763305664
CREBZF	0.024193548387096774	9155.656934578283	9155.648682633726	0.136	0.0082519445568323	0.008695652173913044	153	0.0082519445568323
E2F2	0.016129032258064516	8555.951278196888	8555.76237523766	0.064	0.1889029592275619	0.06086956521739131	69	0.1889029592275619
TBX19	0.008064516129032258	2552.263719105496	2552.263719105496	0.016	0.0	0.0	24	0.9727347493171692
TEAD1	0.0	35.21135154538013	35.21135154538013	0.0	0.0	0.0	4	0.2711718380451202