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#version: 0.2 c c C C cc c ( = n c ] ( C c @ @ cc ccc N C ) [ CC C ( - O C C l ) ( N c cc cc O c CC N CC CC C N n H C Oc ) (= c n ) = O CC 1 2 n cc c nc CC c C O n n CC CCC ( [ CCC N 2 3 2 1 - ] @ ] s c B r C NC CC OCC o c @@ ] C OC C n + ] N Cc N CC nc nc O Cc C S N S cc nc -] ) ccc nc ( / 3 2 n nc 3 4 ) / CC OC cc n CC NC +] (= cn n cc ncc CC Oc cccc n N O CC CCN n ccc CCCC CCCC CC O CC Cc CCC NC cn cc nc n C Nc ]( [ . [ CCN CC S C n cccc 4 3 CC n S c @@ ]( n oc N CCC C OCC O CCN OC O c sc CCCC CC N CCN ccc s @ ]( CS c n o c s CCCC c ( \ N CCc CCC Oc ccc o CC S 1 3 4 5 ) - + ]([ CCC O O CCCN = [ F c N CCCC nn n Cl c + ]( N CCCN CCC n N a N N cc sc OCC O ncc n cn ccc ccc n CC Nc CCCC NC ncc s O P CCCC CCC o n CS C 3 1 CO Cc O CCC CO P CN CC cnc nc cnc n O CCCC )( [ cc oc / [ CO CCN F C S Cc s ccc OCC OCC O S CCC Nc S CC nccc n 5 4 c oc CN Cc OCC c N NC C F O O +] .[ nc nn cn ccn CN S o nc -] )[ CC SC ncc nc CCCC Oc NCC O ]( / cc nn -] .[ CCCCC N CCC S CCCC n NCC CCN \ [ CS CC cn nn 2 4 CCC OC CN CCO CC l CCCCC NC NCC Cc CCC l COCC Oc OCC Cc cn nc n sc CCCC Cc s cc OCC NC CCCCCCCC CCCC n s nc sc S i N CCOCC C P ccnc n O CCCO +] =[ NCC NC CCCC CCN OCC Oc NCC Oc CC Sc 3 5 CCCCCCCC CCCCCCCC O CCCOc cc on CCCC O nn nn Br c NCC Nc OCC n cnc s CCCCC n 5 6 6 5 CCCC OC CN CCc cs cn # [ CCCC CCc no nc N CCCCCC -] #[ CCCC CCCCC o ccc c o CCN S N OC N CCCCC CCN Cc N P CS SC ] ) CCCC Nc cnc o OCC OC 4 2 NCC S nn nc ncn s CCCN CC N CCCCCCCC -] [ OCC CCN OCC F CC F ns nc CN CCN CCCCCCCC CC ncc o NCCC Nc CCS CC s cnc CCO P CCC Sc N Nc O OC CO S NCCC n n ncc CCCC CCOc COCC n CCCC CCNC S CCCN CN CCC COCC O S CCN CCCCC OC CO CCCOc CCCCC Oc o cc OCCN S NC N OCCOCC OCCOCC OC OC CCCCCCCC CCC CCCC S NCC n ccc nn NCCC O COCC NC N CCCCc 1 4 S SC nc oc OCCCC Oc nc ncc ] % -] )([ CCCC CCCCN CO CCC CS Cc COCC Nc 1 0 ) \ CCCCCCCC c S e CC OCc O N 1 1 31 4 CCCC CCCN NCCCC Nc ] )([ o cnc S CCC O CCCCCC OCC CCC O CCCn N CCCNC ccn o 4 6 +] = nnc s CCCCCCCC CCCCC -] =[ NCCC Oc CC P N n 5 3 CO N -] . NCCCCCC Nc O CCCCCCCC nnc n (= [ cc nnc C Br O B s e L i CCCN Cc NCCCC NC s n OCC Nc CCS SC COCC OC CO NC S S ] / CCC F OCC CCCOc CCCCCCCC CCCCCC CCCN S NCCCN CCCCN NCCOCC OCCNC s ccn NCCCC CCC NCCOCC OCCNS CCCC CCn CS CCC CCC OCC CCCCC Nc CCCCCCCC CCCCCCC cs cc CCCC CCCNC COCC c O CCCCc S CCc CCCCC Sc CCCCN S OCC CCCN NCCCC CCNC O CCCNC s nc OCC OCCO CCCC CCCc CCCCCCCC NC CO CCCn NCC OC -] )= CCCCCCCC CCCCN CN CCCNc 6 4 CN CCCN N CCCCCN OC N CCN CCCCc CS CN OCCCC CCN ] [ CCOCC Oc CCS S CCCC CCCOc CCCN CCN CCCCCC Nc CCCCC S CCCCN Cc NCC F OCCCC O NCCOCC OCC CCCCCCCC Oc CCO CCN ( # 1 8 COCC Cc NCCCC CCCNc CCC SC CO CCCN CCOCC n CCO CCC NCCCN Cc OCCC Nc CN CCCC CCCC CCOC 4 1 nc on NCCCCC Nc )( / NCCCC CCN OCCC F NC P )= [ NCCOCC OCCOCC NCCCCCCCC Nc CCN CCc CN CCOc S Sc OCCC OC N CCCCCNC CCCCC O 6 7 nnc o OCCN Cc CCCCCCCCCCCCCCCC CC S CCS CCC OCCn N OCC CCOCC OCCOCC CCCC Sc O CCCCCCC CCCCCCCC CCCCn NCCOCCOCC OCCNS CO n COCC OCCOCC CCS Cc O CCNCC OCC SC CCCCCCCC CCOc - ]( CN CCNC CCCCCCCC n NCCCC O cs nn co cn ] )[ OC P CCCNCCN CCCNCC CCCCN CCCCN OCCC S CN CCNc N OCCO OCCCC Cc NCCCNCCCCN CCCNC c onc NCC Sc cn oc NCC SC NCCN S I c CCCCCCCC CCN CCCCCCCCCCCC CCCCN N CCNCC s nnc NCCC OCCOCCO COCC OCCNC C H NCCN CCO COCC S NCCCOCCOCCO CCCNC 7 6 CCC P OCC S CCOCC O CCCCN CC S CCCc OCC OCc @@] (= S CCO nn sc NCCCC Cc CCCC CCCn COC Oc NCCN Cc NCCCC Oc OCC OCCN CN CCCCCCN OCCCC CCNC C I N NS OC n -]) / OCCCO N NCCCCCCCC CCNc NCCCNCCCCN CCCN CCOCC OCCN NCCOCCOCCOCC NC 8 6 OCCOCCOCCOCC OCCOCCOCCOCC @@ +]([ CS CNC no cc CCN CCC CCCCCCCC Cc CCCCCCCCCCCCCCCC CCNC CN CCCc CCOC n CCCCCCCC CCCCc CCCCCCC Nc OCCCO P CCCCCCCCCCCCCCCCN OC N OCc S CCNC CC Br CO CCCNC @] (= CCOCC c 1 5 ] (= o ncc -] )( NCCCCCCCC NC N NCc CCCC l COC O CCCCCC Sc OCC Sc CCCCCCCC Nc CCN CCN CCN CCO CCCC CCCCCN +]( - OCCCC n NCCCCCC S 12 3 CCCCCC S OCCCC CCOc OCCOCC OCCF (- [ cn ncc CO CCCC CCCCCCCC OC CCCCCCN Cc CCS CCc CCCC F NCCCC CCCCC S CCCS OC F CS CCN CCCOC n COCC OCCOCCOCCOCC 1 6 @ +]([ s ncc CCCCCCCC CCc O NC NC NC CS CCNC NCCCC CCCCN NCCCC CCCNC P H CCCC OCCCCCCNC cn sc CCCCCCCC CCCCOc COCC OCC CCCCCCC OC CCN CCCN CN N CN CCn CCOC P CCCCCCCC CCNC NCCC l NCCCC n O CCCCCCCCCCC CCCC CCO CO CCCNc +] [ CCNCC Nc COCCN Cc CCCCCCCCCCCCCCCC NC CCCCCCCCC Oc N CCCCCCCCCCCC O CCCCCCCCCCCC ] )( s sc CN CCCCN CN CCCO CCCCC OCc OCO P 7 5 O CCCCNC 12 5 CN CCCOc CN CCS CCCN CCCNC CCO N NCCOCC OCCN CO B CCCCC NCc CCCCN CCOc OCCCN Cc COCCN S CCCCCCCCCCCC CCOc @ +] CN CCCCc CO CCCCn CCOCC OC CCO S CCCCCCCC CCCCNC CNCCC P 5 2 S CN CS S NCCC OC CCCCCCCCCCCC CCCCC cccc cc OCC CCCO CS SCCC CCCCCCCC CCCOc NCCCC CCn O n S CCCC CCCC OP NCC SCc CCO NC NCCCC CCCN N Oc S CCCO CN CCCNC (/ [ CCCCCCCC CCCNC OCCOCC F OCCOCC OCC s s CCC OCc CCCC B CCCN CCc CS CCCCCC CCO n CCCCCCCCCCCC CCNC F CCOc Z n CO Nc nn ccc ccn s CCCCN CCCN CCCCCCCCCCCCCCCC OCC NCCCCCCCC CCCCNC 1 7 8 7 n scc NCCCC CCc CCN CCOc CCCC CCNCC OCC CCCn CCOCC NC COC P CCCCCCCC S COCC CCN 31 5 OCCC SC OCCCC CCc NCCO NC 1 9 S CCOc Cl C CCN CCCc OCCOCC OCCNC CCCCCCCCCCCCCCCC CCOCC @ +]( n ncnc CCCC CCCCCNC CCCN CCC CS CCc CS CCNc OCCN CCOc NCCCC CCCCCNc OCCCC CCO OCCOCC OC OCCOCC OCCO O CCCCCCCCCCCCCCCC cn sn CO CCCS CS CCCN CCCCCCCC CCOC NCCC S CCCCCCC Sc OCCCC CCCN NCCCCCCCC CCC 7 8 S N S CCn OC S Cl CCN CCCN CCCN COC N CS SCC CCCCCCCC CCn COCC OCc CCCO P OCCCC Nc CCCS CCN NCCCCC O OCCOCCO CCC NC B CN P COCC OCCN NCCCC CCO +]( / OCCCC CCCCN NCCOCC O OCCCCCCCC CCCCCC S CSc CCCCC NCC CCOCC OCCO cnn s CCCCN CCc CCCCCCCC CCCc NCCCN CCCCCCN OCCOCC Oc CCCCCCCCCCCC OC CNCCCC CCCCCN NCCCCCCCCCCCC Nc 43 1 NCCC OCC COCC F NCCCC CCCCCNC 2 0 2 5 S CCCCCC CC I CCCC CCCCCn CN CCCn OCC Br CCCN CCOc )/ [ CCCCCCCC O CCCCCCCC CCNc CCCCCCCC CCCCCc OCCCC CCn CCCCCCCCCCCCCCCC CCOC NCCS SCCNC SS S S CCOP @@ +]( CCCC OCC CCCC CCCO CCCC OCCOc CN NC CN CCCCCCCCNc CCCCC l @] % CS CCO CCNCC S OCCC P OCCC Sc NCCOCC OCCOCCOCCOCC OCCOC P 1 32 5 7 O CCCCCCCCCC CCC Br CCCC OCc CN CCNCC CCCCC NS CCOCC OCCNC CCOCC OCCOc NCC SCC COCC OCCOc CCS CCCC CCS SCCC OCCCN CC NCCCN S NCCCN CCCCCCCN NCCCN CCCCCCCCCCCCN CCCCCCCCCCCCCCCC OCCCOP CCCCCCCCN CCCCCCNCc 10 9 OCCCCCC Nc F CCn OC Oc CCCC P CCCC Br CN CCOC CCOCC OCCOCCOCCOCC COC n CS N CCOC N NO CCCCCC COCC P COCC OCCOC OCCN CCc NCCCC CCOC +]( \[ OCCO CCC OCCC OCc CCCCCCCCCCCC Nc OCCCCCCCC NC COCCOC Oc CCCCNCCCCN CCCCNCCCCN NCCCNCCCCCCCN CCCNC 3 6 F CC OC OCCOC CN O CN CCCCCCNc CO CCCO NO S OCCN CCO NCCCN CCCN OCCOCC NC OCCOCC OCCOCCO NCCCCN CCCCN NCCOCC OCCNc CCCCCCCCCCCCCCCC OC CCCCCCCCC Nc NCCCCC Oc NCCCCCCCC c NCCOCCOCC OCCN CNCCCCCCN CCCCCCCCNCCCCCCNCc 6 3 A s B P cc sn NC S CO OC CO CCNCC CS CCCC CCCCCCCC CCCN CCCCCCCC CCO OCCN CCCOc CCS CCC CCCO N NCCCC CCOc CCCCCCCCCCCC S CCOCCOCCOCC NC CCNCCS SCCN - [ S CCCCC S CCCn S CCNS CCCC CCOCC CN Nc ncc nn CCCN CCNc CCOCC Nc CCOCC Sc CCOCC OCCOCCOCCOCCOCCOCCOCCOCC COC OC CS CCCNC NS C NO CCN CCO CCCNC NCCC F OCCCC CCCCC OO CCCO NCCOCC Oc CCCCCCCCC OC co cc NCCCCC OC COCCOCCOCC Oc NCCCNCCCCCCN CCCNC 2 2 S CSC CN CCNS CCCN CCCc CNC N CCOCC OCc NCC Br 34 1 CCCCCCCC CCS NCCN CCc OCCCN S OCCO P OCCC l OCCOCC OCCOC CCCCCCCCCCCC CCOC NCCCCCCCC CC OCCCCCCCC Oc CCOCCOCCOCC n CSS SSC OOCCCO O 6 8 8 9 S CCCCN CCC SCC CCN CCCC CCN CCCNCCN CN CCCCCC CCCCC OCC @]( / CCCO CCCOc OCCOCC n CCCCCCN S NCCCCCCCC CCN SCCC SCC NCCOCCOCCOCC n CSCCCCCC SC 9 8 O CCCCCCCCCCCCC CC B CN CCCCNc CN CCCCCCCNc CO CCCCc CCOCC Cc CS CCCc CCCCN CCN COCC CCCN CCCCCC SSc NCCCC CCNS NCCCN CCCNCCCNC CNCC F CCCS SCCCC NCCCCN CCCN NCCCCN CCCCNCc CCCCCCCCCCCC CCN CCCCCCCCCCCC CCc NCCOCC Nc CCCCCCCCCCCCCCCC CCC NCCCCCCCC n OCCOCCOCCOCC NC CNCCCCCCN Cc B H N CCCCCn S H @@ +] @@ ]([ CCN CCCOc CN CCCCNCCCCN CN CCCCCCCCCNc OCC CCCNC OCC CCCNc OCC SSC CCCCC F CCCN CCCNCC CCOCC OCC NCC OCc NO CCCOc CCCCCCCC Sc CCCCCCCC CCCO NCCCC CCCCCN NCCCN CCCNc NN NN CCCCCCCCCCCC CCCc NCCOCC OCCOCCOCCC NCCCCCCCC Oc OCCOCCOCCOCC Oc SS SSS OCCNCC Nc OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCC CCCCCCCCCCCCCCCCCCOCC OP NCCCNCCCCCCCCCCCCN CCCNC 6 9 N NCCO N OCCNC T e NC SC CCC OCCc CN CCCCNCc CN CCCCNCC CCOCC OCCn @@] % NCC OCCN CCCCCCCC CCCOC CCO CCCC CCO CCCN CCO CCCO COCC CCC OCCN CCCc cs sc NCCCC CCCc OCCOCC OCCN CCCCCCCCCCCC CCCN CCCCCCCCCCCC CCO CCCCCCCCCCCC CCCCCNC NCCCCCCCC CCNC NCCCCCCCC CCCCN CCCCCCCCN Cc CCCCCCCN Cc O CCCCCCCCc S CCCCCCCC S CCCCCc Cl CCl CCN CCCNc CCCC SC CN OC OCC SS CCCCC Br Br C CCOCC OCCNS SC F COCC Sc OCCN CCN OCCN CCCCN OCCN CCCCc cs nc CCCO S CCCO n NCCCC CCNCc NCCCN CC OCCO S OCCC OCC OCCC Br OCCCC F OCCCC OC CCCCCCCN S OCCCCCCCC n OCCCCCCCC CCOc CCOCCOCCOCC Oc NCCNCC Nc OCCS CCOC COCCOCCOCCOCCOCC OCCOCC NCCCCCCCCN CCCCNC CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCNC S CCOC S CCCCCN CCC OCCCc OC SC CCN CCCCN CCN CCCCCc CCCC SCC CCCC OCCCOc CN CCCCOc CCCCC SC CCCN NC CCCN CCCNc CCCN CCCCNCCCN 21 3 CCOCC S CS CCSC CCCCCCCC CCCCCCCCCCCC CCCCCCCC CCNCc NCCC SC CCCCCC P CCS SCC CCCO CCCN NCCCC l NCCCN CCCCNC NCCCN CCCCCN OCCCC Br SCC SC NCCCCN S NCCCCN Cc CCCCCCCCCCCC CCCNC CCCCCCCCCCCCCCCC S CCCCCCCCCCCCCCCC OP CCCCCCCCC O NCCCCC S NCCCCC NCCCCCCCNC NCCCCCCCC CCCN OCCCCCCCC CCN CCCNCCN CCNCCC NCCOCCOCCOCC Oc CCCCCO NC CCOCCOCCOCC OCCNC CCOCCOCCOCC OCCOCCC COCCOCCOCC OC COCCOCCOCC OCCOCc CSCCCCCC SCC CCNCCSSCCN CCC NCCCNCCCCCN CCCNC O H S CCCOC S CCCCCSc o ccn CCC I CCN NC CCN CCCCOc CCN CCCCNCCCCN CN CCCCC CN CCCCNC CN CCCS OCC P OCC CCCOC CCCN CCCCNc CCOCC F CCOCC OCCOCCN +] / +] #[ NCC OP CS CCOc CS CSC CCOC Oc ncn o CCNCC n NCCC P NCCC Sc COCC OCCO NCCN CCN CCS CCn OCCCN CCc NCCCC CCCn NCCCN CCCCCCCCNC CCCCCCC OCC CNCC Sc OCCCC CCOC OCCCC Sc OCCOCC Nc OCCOCC OCCn NCCOCC OCCOCCOCCOCCOCCOCCOCCOCC CCCCCCN CCOc CCCCCCCCCCCCCCCC CCCCC CCCCCCCCCCCCCCCC CCOP CCCCO N OCCOC n OCCCCCCCC O CNCCCC CCNCCSSCCN NCCCCCCCCN CCCCCCCCNC COCCCO CCCCOCCCOc NCCCNCCCN CCCCNCCCN CNCCCCCCNCCSSCCN CCCCCCNCc 3 7 6 1 C B F Cc O Nc S NC S CCCCO S CCCCCCCCc CCC OCCOc OC Sc CN CCCNCc CO CCCOC CCCCC P CCCN CCNS +] # CS CO CS CCCCC CCOC OC CCCCCCCC CCCn CCCCCCCC OP CCO CCCOc NCCC OP CCS Sc NCCCC P NCCCN CCCNC OCCCC CCCOc OCCCC CCCCCN SCC OCc CCCCCCCCCCCC O CCCCCCCCCCCC CCCO CCCCCCCCCCCCCCCC CCN CCCCCCCCCCCCCCCC SCC NCCCCCCCC O OCCCCCCCC CCCCOc CCCCCCCCCCCCN CC CNCCCC CCOCCOCc CCOCCOCCOCC OCCn COCCOCCOCC OCC CCNCCCN CCCNCCCNCC CNCCCCN CCCCNC CCCNCCCN CCCCNCCCN NCCCCNCCCCN CCCCNC CCCCCCCCCCCCCCCN OC - % 3 21 F CCCOc N NCCc S NCc S NCCc S SCC s scc t e OC OCC CCN CCCCC CCN CCCCNc CCN CCCNCC CCCC CCOP CN CCNCc CN CCCCCCCCCCNCc cn on CO CCCCOc CO CCCNCc CCCN N CCCN CCCOc CCCN CCCCCCNc 23 1 CCOCC P CCOCC OCCOCc COC OCCOCCOCCOCCO CS CCn CS CCCCCCCCN CCO CCCCOc COCC OCCNc COCC OCCCCCCNC NCCN CCNC CCS CCO CCCO CCCNC OCCCN CCOc OCCCN CCO NCCCC OC NCCCN CCN COCCN CCOc OCCOCC c OCCOCC OCCCN CCCCCCCCCCCC P NCCOCC OCCO NCCOCC OCCOc OCCCO NC OCCCO CCCC OCCCO CCCOc CCCCCCCCCCCCCCCC n OCCOCCOCCOCC n CCCCCCCCN CC CCCCCCCCN CCCCCCN CCCCCCCCCCCCC O OCCCCCCCC CCCCCCC CCSS CCNC CCOCCOCCOCC F NCCCCCCCCN CCCN CNCCCCN CCCCNCc CSS SCc OCCOCCOCCO CCC 3 12 5 1 F CCC F CCc F CCCN S CO S CCCCCn ] = NC O NC n CCC OCCNC OC OCc OC OCCO CCN N CCCC I CN n CN CCCNCC CN CCCCCCCCNCc OCC I CO CCCCCC CCCN CCCCN CCCN CCO ncnc n CS CCOC CS Sc CS SCCNC NO CCCO CCCCN P CCCCCCCC CCOCC CCCCCCCC CCNCC CCCCCCCC CCCCCN CCO CCCn NCCC OCCOCCOCCCN CCCCCC F CCCCCC l CCCCCC Br CCCCCC SCC CCS CCNC CCCO NC NCCCN CCCCCC NCCCN CCCCCCCCN CNCC P OCCCC CCCn OCCOCC OCCOc NCCO B NCCCCN CCCNc CCCCCCCCCCCC SC NCCOCC NC CCCCCCCCCCCCCCCC c CCCCCCCCCCCCCCCC CCSCC CCCCCCCCC NCC NCCS CCN NCCCCCCCC CCc NCCCCCCCC CCCNC CCCCCCCCN S COCCC SC OCCCCCCCC OC OCCCCCCCC Nc OCCCCCCCC CCOC SS SS NCCOCCOCCOCC OCCOCCOCCC COCCOCCOCC OCCOc COCCOCCOCC OCCOC COCCOCCOCC OCCNc CCNCCN CCNCC CNCCS CCCNCCc OCCCCCCCCCCCCCC Br CCCCNCCCCNCCCCNCCCCN CCCCNCCCCNCCCCNCCCCN COCCNCC n OCCSS CCO 7 2 7 4 F CCOCCOCCOc N H N NCC N NCCN N OCCOc S CCNc S CCCCCCC S SCc S SCCC S CCOCCN S CCOCCSc NC Nc NC Oc CCC SCc OC OCO Cl CC CCN P CCN n CCN CCNC CCN CCCCNC CCN CCCS CCN CCNS CCCC OCCN CCCC SCc CCCC OS CCCC OCCCc CN CCCCO CN CCCCCNCc CN CCCCCCCCCCNc OCC CCCSc OCC CCCNCc cnc nn CO NS CCCCC NCCc CCCCC SCC CCCCC SS CCCN CCCC CCCN CCCCc CCCN CCCCCCCCC -] / CNC P CCOCC CCN CCOCC OCCOC COC OCCC +] % NCC CCNCC CS CSc CS CCCNc 34 5 CCOC O CCCCN CCC CCCCN CCCc CCCCCCCC P CCCCCCCC CCSC CCO B CCO NCCCOc NCCC Br NCCC OCCOCCOCCNC COCC OCO COCC OCCC COCC OCCn COCC OCCOCCO COCC CCCP OCCN CCC CCCCCC SC NCCN CCC NCCN CCOC NCCN CCNCCNc CCS CN CCS SCCN NCCCC CCCS NCCCC CCCNS NCCCC CCCCNS +]( /[ NCCCN CCO NN N OCCO NC CCCCCCC P CCCCCCC S OCCCC CCCc OCCCC SC OCCCC CCCCCOc COCCN CCN OCCOCC OCc NCCCCN CCCNC CSCC F CCCCCCCCCCCC CCn CCCCCCCCCCCC CCCOc NCCOCC n NCCOCC OCCC NCCOCC OCCOCCO NCCOCC OCCOCCC OCCCO CCCN CCCCCCCCCCCCCCCC O CCCCCCCCCCCCCCCC Oc CCCCO B CCCCCCCCC S CCCCCCCCC OCC CCCCCCCCC Sc NCCCCC NCc NCCCCC NS NCCCCC Sc NCCCCCCCC CCOCC NCCCCCCCC CCCCCCC CNCCN CCCN CNCCN CCNCc COCCO n OCCOCCOCCOCC OC OCCOCCOCCOCC OCc OCCOCCOCCOCC OCCOc CCCCCCCCN CCCNCc NCCCNCCCCN Cc NCCCNCCCCN CCCNCc CCCCCCCCCCCCN Cc CNCCCN CCCCCCCCNCCCNCc CCCNCCN CCCN CNCCCC CCO NCCOCCOCCOCC OCCN CCOCCOCCOCC OCCOc COCCOCCOCC OCCO OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCNC CCNCCN CCN COCCOCCOCCOCCOCC F COCCOCCOCCOCCOCC OC COCCOCCOCCOCCOCC Oc CCNCCCN CCNCC OCCCCCCCCCCCC O OCCCCCCCCCCCC OC OCCCCCCCCCCCC CCOC NCCOCCOCCOCCOCCOCC OCCOCCNC NCCCNCCCCCCCCCCCCN CCCN NCCCNCCCCCCCCCCCCN CCCNc OCCOCCOCCOCCO P NCCCCNCCCCN CCCCNCc NCCCCNCCCN CCCCNC CCOCCOCC OCCNS CCOCCCC CCOCCc COCCOCCOCCOCCOCCOCCOCC OCCNc CCCCCSS CCCCC ) # 1 42 8 5 A l C a F CCN F CCCC F CCOCCOc N OCCCc O OCCC S CS S CCCNC S CCNCC S CCCCc S CCCCNC S CCCCOc S CCCCSc S CCCCCCCSc cc s NC OCc NC NS CCC OCCN OC OCCN OC OCCn Cl CCOc CCN CCCNC CCN CCCCCC CCN CCCO CCN CCCCCN CCN CCCCNCCN CCN CCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCN CN CCCCCN CN CCCCCc CN CCCCCCNC CN CCCCCOc CN CCCCCCCN CN CCCCCNc CN CCCCCCCCCCN CN CCCCCCCCCCCCNCc OCC l OCC OCCCN CO O CO NCc CO NCCOc CO CCCNS CO CCCCCCP CCCCC NCCNS CCCN CCCCCCCCN CCCN CCCCCCCCCCCCN Br CC CCOCC OP CCOCC OCCF CCOCC OCCNc NCC OS CS COc CS CCCCN CS CCCOc CS CCNCc CS SSC CCOC Sc NO P CCCCN NC CCCCN CCCCCNC CCCCCCCC OCC CCCCCCCC SC CCCCCCCC SCC CCCCCCCC CCCCCn CCCCCCCC CCOP CCCCCCCC CCCCCOC CCCCCCCC CCCCCCCCCCCCOC CCO OC CCO NCc CCO CCCNc CCO CCCF CCNCC F SC P @@]( / NCCC OCCO NCCC OCCCC COCC CCCn COCC OCCOCc COCC OCCOCCN COCC OCCOCCOCCOCCOCCOCCOCCOCC OCCN CCCNc CCCCCC OCc NCCN CCCN CCCO B CCCO CCC CCCO Nc CCCO NCCOc NCCCC S NCCCC OCc NCCCC CCCOc NCCCC CCCCNCc NCCCN CCNc NN CCCCC OCCO N OCCC OCCCCC OCCCC l OCCOCC OCCOCCN SCC F SCC l CCCCCN OC CCCS CCC NCCCCN CCCNCc NCCCCN CCCCNCCCCN NCCCCN CCCCCNCc CCCCCCCCCCCC CCCn CCCCCCCCCCCC OS CCCCCCCCCCCC CCCCCNOC NCCOCC OCCn NCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCCO CCC CCCCCCN CCCCCCN CCCCCCCCCCCCCCCC Nc CCCCCCCCCCCCCCCC CCO CCCCCCCCCCCCCCCC CCS CCCCCCCCCCCCCCCC OCCO CCCCCCCCCCCCCCCC OS CCCCCCCCCCCCCCCC OCCOP CCCCO n CCCCCCCCC NCc NCCS CCC OCCOCCOCCOCC F OCCOCCOCCOCC OCC NCCCO CCCNC CCCCCCCCN CCOc SCCC F CCCCCCCCCCCCC I OCCCCCCCC Cc OCCCCCCCC CCCNC OCCCCCCCC CCCOc OCCCCCCCC CCCCCc SS Sc CCCCCCCCCCCCCC S CCCCCCCCCCCCCC Sc NCCCNCCCCN CCC CCCCCCCCCCCCN CCOc CCCCCCCCCCCCN CCCCCCN CCCCCCCCCCCCN CCCCCCNCc CNCCCN CCCCCCCN NCCCCCN CCCCCN NCCOCCOCCOCC OCCn COCCOCCOCC NC COCCOCCOCC OCCOCCO CCCCCCCCCCN CCOc CCCCCCCCCCCCCCCCN CCOc COCCOCCOCCOCCOCC OCC OCCCCCCCCCCCC S NCCCCCCCN CCCCCCCNC OCCOCCOCC CCCNC OCCCCCCCCCCCCCCCC OC NCCOCCOCCOCCOCCOCC OCC CCOCCOCCOCCOCCOCC n CCOCCOCCOCCOCCOCC OCCOCCC CCCCNCCCCNCCCCNCCCCN CC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC CCCCCCCCCCCCCCO CCCOP OCCSS CCOC COCCOCCOCCOCCOCCOCCOCC OCCOCc CCNCCCCNCCCCN CCCCN CNCCCS CCNCCc NCCNCCN CCNC NCCOCCOCCOCCOCCOCCOCCOCCOCCOCC NC OCCCOCCCC OCCCOCC NCCCNCCCCCCCCN CCCNC CCCNCCCCCCCCC NCCCN CCCNCCCCCCCCCCCCN CCCN NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC 2 6 5 8 5 43 5 13 7 3 = % F CCNC F CCCc F CCOCCO I C M g N CCCCCCCCCCCCCCCCCC N OCCOCCOCCOCCC O OCCCC O NCCCOc O OCCCCCCO S Nc S CNC S COC S NCC S CCCOc S CCCCn S CCCl S CCNCc S CCCSc S CCCCCCCCN S CCCCCNc S CCOCCOCCOCC S CCCCCCCCCc S CCCCCCS S CCOCP S CCCCCCO s snc NC OC NC Sc NC OCN NC NCCCCS CCC OCCOC OC B OC NC Cl CCC Cl CCCN Cl CCCc Cl CCn Cl CCNc CCN CCOC CCN SC CCN CCCCCCC CCN CCCCCCc CCN CCCCCNc CCN CCCCCCNc CCN CCCCNCC CCN CCCCNCCCN CCCC OCCn CCCC OCCOC CCCC CCCNCC CCCC OCCF CCCC OCCCCC CCCC OCCCCCN CCCC OCCOCCOCCOCCOCC CN CCCCn CN CCCl CN CCCSc CN CCCCCCCCN CN CCOCCOc CN CCCCCO CN CCOCCO CN CCOCCOCCNC CN CCCCCCCCCCCCNc CN CCOCCOCCNc CN CCCCNCCCCNCCCCNCCCCNCC OCC CCCS OCC CCCNCC OCC OCCNCc CO CCCCNC CO CCCCCCC CO CCCNCC CO CCCCCCNC CO CCCCCCCCCCC CO CCCCCCCN CO CCCCCCCCCCCCCCC CO CCCCCCCCNC CO CCCCCCCOc CCCCC B CCCCC NCCCN CCCCC OP CCCCC SCc CCCCC NCCOc CCCCC SCCCN CCCCC OCCCCCN CCCCC OCCCCCCCCCc CCCN P CCCN CCCCCC CCCN CCCO CCCN CCCCCc CCCN CCCCCCCCCCN -] )(= CNC O CCOCC I CCOCC CCCN CCOCC CCCO COC NC COC Nc COC OCC COC OCc COC OCCS NCC P CS COC CS CCCCCCCC CS CCS CS CCCS CS CSCC CS CCCCCc CS CCCCCCCCC CS CCNS CS CCSCC CS SCCN CS CCCCl CS CCCCCSC CCOC S CCOC OCCOC NO NC NO CCC CCCCN CCCC CCCCN CCO CCCCN CCCNCC CCCCCCCC F CCCCCCCC OS CCCCCCCC CCNS CCCCCCCC CCF CCCCCCCC CCSCC CCCCCCCC CCCCCOc CCCCCCCC OCCCCCN CCCCCCCC OCCCOP CCO CCNCC CCO CCCCCCC CCO CCCCCCCCCCCC CCNCC P 43 5 NCCC OCc COCC CCCNC COCC CCCOc COCC OP COCC OCCCc COCC OCCS COCC OCCSc COCC OCCCNCc OCCN CCCC OCCN CCCO OCCN CCCSc OCCN CCOCCNc NCCN CCCc NCCN CCCNC NCCN CCCCCC NCCN CCCCCCC CCS CS CCS CCOC CCS CCNc CCS CCCCNC CCS CCCCCCCCCCCC CCS CCSCC CCS SSC CCCO OC CCCO CCCC CCCO CCCCCCCNC OCCCN CCC OCCCN OC OCCCN CCN NCCCC CCNCC NCCCC CCOP NCCCC CCCSc NCCCC CCOS NCCCN CCC NCCCN CCNC NCCCN CCCCCCCCC NCCCN CCCCCNCc NCCCN CCCNCCCN NCCCN CCNCCCNc OCCO CCCC OCCO CCCCO CCCCCCC Br CCCCCCC SCc CCCCCCC SCC CCCCCCC OCCCCCN OCCCC CCNCC OCCCC CCNS OCCCC CCCCCOC OCCCC CCCCCNc OCCCC CCCCCO COCCN CCC COCCN CCc SCC Sc OO CCCCCC CCSC F CCCCCN P CCCS S CCCS CCCC CCCS SC NCCCCN N NCCCCN CCCCC NCCCCN CCCCNC NCCCCN CCCCCCCN CCCOC OC CNCCO NC CCCCCCCCCCCC CCOCC CCCCCCCCCCCC CCNCC CCCCCCCCCCCC Sc CCCCCCCCCCCC OP CCCCCCCCCCCC SCC CCCCCCCCCCCC CCOP CCCCCCCCCCCC OCCCOP CCCCCCCCCCCC CCNCCOc NCCOCC c NCCOCC Cc NCCOCC OCCNCc NCCOCC OCCNCC OCCCO n OCCCO CCCOCCCOc CCCCCCN CCC CCCCCCN CCCCCCNCc CCCCCCN CCCCCCCCNCCCCCCN 35 1 CCCCCCCCCCCCCCCC Cc CCCCCCCCCCCCCCCC CCOc CCCCCCCCCCCCCCCC CCn CCCCCCCCCCCCCCCC CCCCCC CCCCCCCCCCCCCCCC CCOCCO CCCCCCCCCCCCCCCC CCOS CCCCO CCCCc NCCCCCC Sc CCCCCCCCC OP CCCCCCCCC SCC CCCCCCCCC OCCCCCN NCCCCC F NCCCCC OCCN NCCCCC NCCCCN NCCCCC NCCCCCCN 42 5 NCCS CCCC NCCS CCc NCCS CCNC NCCS CCO NCCS CCCc NCCS SCCC NCCCCCCCC CCCCC NCCCCCCCC CCCCCC NCCCCCCCC CCNS OCCCCN CCc CNCCN CCNC CCCCCCCCCC P CNCCC F CNCCC OCCNCCc CNCCC OCCOCCc SCCN CCCc SCCN CCCOc OCCOCCOCCOCC Nc OCCOCCOCCOCC OCCOCCOC OCCOCCOCCOCC OCCOCCOc CCCCCCCCCCC SC CCCCS SC NCCCO N 10 8 Se H 11 8 CCCCCCCN CCNS SCCC OCC OCCCCCC F OCCCCCC Br OCCCCC Br OCCCCC SC CCCCCCCCCCCCC Sc CCCCCCCCCCCCC NCCCCCCNCc OCCCCCCCC CCO OCCCCCCCC CCn OCCCCCCCC CCNc OCCCCCCCC CCCCn COCCOC N COCCOC OCC COCCOC OCCN SS CCO NCCCNCCCCN CC NCCCNCCCCN CCCn NCCCNCCCCN CCCNc CNCCCN CCc CNCCCN CCNCCCN CCCCCS Sc CCCCCS CCCCCCCCCC CNCCCC CCCNCC NCCCCCCN CCCCCN CCOCCOCCOCC OCc CCOCCOCCOCC CCCNC CCOCCOCCOCC OCCN CCOCCOCCOCC OCCSSC COCCOCCOCC F COCCOCCOCC OCCNC CCCCCCCCCCN CCCCCCNCc CCCCCCCCCCCCCCCCN CC OCCS SCCN CNCCCCCCN S CNCCCCCCN CCCCC CNCCCCCCN CCCCCCCN CNCCCCCCN CCCCCCCCCCCN CNCCCCCCN CCCCCCCCCCCCNCCCCCCNCc CNCCCCCCN CCCCCCNCCCCCCNCc CNCCCCCCN CCCCCCCCCCCCCNCCCCCCNCc CNCCCCCCN CCCCCCCCCCNCCCCCCNCc NCCCNCCCCNCCCN CCCCN NCCCNCCCCNCCCN CCCCNC OCCOCCOCCOCCOCCOCCOCCOCC OC COCCCC P NCCCCCCCCC NCCN COCCOCCOCCOCCOCC OCc COCCOCCOCCOCCOCC OCCO COCCOCCOCCOCCOCC OCCOC COCCOCCOCCOCCOCC OCCOCCO COCCOCCOCCOCCOCC OCCOCc COCCOCCOCCOCCOCC OCCOCCOCCOCCO CCNCCCN CCCNCCCNC CCNCCCN CCCCNCCCN CCNCCCN CCCNCCCN CCCCCCO CCCCCCCC CCCCCCO CCCCc OCCCCCCCCCCCC CCOc SCCCC P NCCCCCCCN CCCCN NCCCCCCCN CCCCCCCN CCCNCCCN CCCNc CCCCCNCC CCNCC NCCCNCCCCCCN CCCCCCCCNCCCCCCNCc NCCCNCCCCCCN CCCCCCCCNCCCCCCN NCCCNCCCCCCN CCCCCCCCCCCCNCCCCCCN CCCCOCC CCCNC NCCOCCOCCOCCOCCOCC NC NCCOCCOCCOCCOCCOCC Nc NCCOCCOCCOCCOCCOCC OCCOCCOCCC CCOCCOCCOCCOCCOCC OCCNC CCOCCOCCOCCOCCOCC OCCOCCOCCNC CCOCCOCCOCCOCCOCC OCCOCCOCCOCCC NCCCNCCCN CCCNCc CSCCCC SC CCCCCCOCC CCCN CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCNC CNCCCCNCCCCN CCCCNCC OCCSS CCNC CCNCCCCNCCCCN CCCCNC CNCCCS CCOCCc COCCOCCO CCCNC NCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCC NCCCNCCCNCCCCNCCCN CCCNS OCOCC OCO NCCCNCCN CCCNC CCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCN CCCCNCC CCNCCCS CCNC CNCCNCCCN CCNC CNCCCCCCO CCCCc CCNCCCO CCCNCC CCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCN CCCCN CCCNCCCCCCCCN CCCN NCCCOCCO OCCCCCNC NCCCOCCCC OCCCNC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCC CNCCCNCCCCCCCN CCCNCc CCNCCCCNCCCCNCCCCN CCCCNC CNCCCCCCNCCCCCCCCCCCN CCCCCCNCc |