MapPFN / README.md
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metadata
license: mit
language:
  - en
library_name: jax
tags:
  - perturbation-prediction
  - prior-data-fitted-networks
  - in-context-learning
  - single-cell
  - causal-inference
  - diffusion-transformer
datasets:
  - marvinsxtr/MapPFN
pipeline_tag: other

MapPFN Weights

Pre-trained and fine-tuned checkpoints for MapPFN: Learning Causal Perturbation Maps in Context (Sextro et al., 2026).

Checkpoints

  • model.ckpt — Pre-trained on synthetic biological prior (50 dimensions, 400k steps)
  • model_finetuned_frangieh.ckpt — Fine-tuned on Frangieh et al. (2021)
  • model_finetuned_papalexi.ckpt — Fine-tuned on Papalexi et al. (2021)

All checkpoints share the same MMDiT architecture (~25M parameters) and differ only in training data. See the GitHub repository for inference and fine-tuning code.

Citation

@article{sextro2026mappfn,
  title   = {{MapPFN}: Learning Causal Perturbation Maps in Context},
  author  = {Sextro, Marvin and K\l{}os, Weronika and Dernbach, Gabriel},
  journal = {arXiv preprint arXiv:2601.21092},
  year    = {2026}
}

Links: Paper | Code | Datasets | Project Page