license: mit
pipeline_tag: token-classification
widget:
- text: >-
Background: Coronaviruses have been the cause of 3 major outbreaks during
the last 2 decades. Information on coronavirus diseases in pregnant women
is limited, and even less is known about seriously ill pregnant women.
Data are also lacking regarding the real burden of coronavirus disease
2019 (COVID-19) infection in pregnant women from low/middle-income
countries. The aim of this study was to determine the characteristics and
clinical course of COVID-19 in pregnant/puerperal women admitted to ICUs
in Turkey. Methods: This was a national, multicenter, retrospective study.
The study population comprised all SARS-CoV-2-infected pregnant/puerperal
women admitted to participating ICUs between 1 March 2020 and 1 January
2022. Data regarding demographics, comorbidities, illness severity,
therapies, extrapulmonary organ injuries, non-COVID-19 infections, and
maternal and fetal/neonatal outcomes were recorded. LASSO logistic
regression and multiple logistic regression analyses were used to identify
predictive variables in terms of ICU mortality. Results: A total of 597
patients (341 pregnant women, 255 puerperal women) from 59 ICUs in 44
hospitals were included and of these patients, 87.1% were unvaccinated.
The primary reason for ICU admission was acute hypoxemic respiratory
failure in 522 (87.4%), acute hypoxemic respiratory failure plus shock in
14 (2.3%), ischemic cerebrovascular accident (CVA) in 5 (0.8%),
preeclampsia/eclampsia/HELLP syndrome in 6 (1.0%), and post-caesarean
follow-up in 36 (6.0%). Nonsurvivors were sicker than survivors upon ICU
admission, with higher APACHE II (p < 0.001) and SOFA scores (p < 0.001).
A total of 181 (30.3%) women died and 280 (46.6%) had received invasive
mechanical ventilation (IMV).
- text: >-
Importance: Atrial cardiopathy is associated with stroke in the absence of
clinically apparent atrial fibrillation. It is unknown whether
anticoagulation, which has proven benefit in atrial fibrillation, prevents
stroke in patients with atrial cardiopathy and no atrial fibrillation.
Objective: To compare anticoagulation vs antiplatelet therapy for
secondary stroke prevention in patients with cryptogenic stroke and
evidence of atrial cardiopathy. Design, setting, and participants:
Multicenter, double-blind, phase 3 randomized clinical trial of 1015
participants with cryptogenic stroke and evidence of atrial cardiopathy,
defined as P-wave terminal force greater than 5000 μV × ms in
electrocardiogram lead V1, serum N-terminal pro-B-type natriuretic peptide
level greater than 250 pg/mL, or left atrial diameter index of 3 cm/m2 or
greater on echocardiogram. Participants had no evidence of atrial
fibrillation at the time of randomization. Enrollment and follow-up
occurred from February 1, 2018, through February 28, 2023, at 185 sites in
the National Institutes of Health StrokeNet and the Canadian Stroke
Consortium. Interventions: Apixaban, 5 mg or 2.5 mg, twice daily (n = 507)
vs aspirin, 81 mg, once daily (n = 508). Main outcomes and measures: The
primary efficacy outcome in a time-to-event analysis was recurrent stroke.
All participants, including those diagnosed with atrial fibrillation after
randomization, were analyzed according to the groups to which they were
randomized. The primary safety outcomes were symptomatic intracranial
hemorrhage and other major hemorrhage.
Model Card for Model longluu/Clinical-NER-NCBI-Disease-GatorTronS
The model is an NER LLM algorithm that can classify each word in a text into different clinical categories.
Model Details
Model Description
The base pretrained model is GatorTronS which was trained on billions of words in various clinical texts (https://huggingface.co/UFNLP/gatortronS). Then using the NCBI Disease dataset (https://www.sciencedirect.com/science/article/pii/S1532046413001974?via%3Dihub), I fine-tuned the model for NER task in which the model can classify each word in a text into one of the categories ['no disease', 'disease', 'disease-continue'].
Model Sources [optional]
The github code associated with the model can be found here: https://github.com/longluu/LLM-NER-clinical-text.
Training Details
Training Data
This dataset contains the disease name and concept annotations of the NCBI disease corpus, a collection of 793 PubMed abstracts fully annotated at the mention and concept level to serve as a research resource for the biomedical natural language processing community. Details are here https://www.sciencedirect.com/science/article/pii/S1532046413001974?via%3Dihub.
The preprocessed data for LLM training can be found here https://huggingface.co/datasets/ncbi_disease.
Training Hyperparameters
The hyperparameters are --batch_size 24 --num_train_epochs 5 --learning_rate 5e-5 --weight_decay 0.01
Evaluation
Testing Data, Factors & Metrics
Testing Data
The model was trained and validated on train and validation sets. Then it was tested on a separate test set. Note that some concepts in the test set were not available in the train and validatin sets.
Metrics
Here we use several metrics for classification tasks including macro-average F1, precision, recall and Matthew correlation.
Results
{'f1': 0.876008064516129, 'precision': 0.9052083333333333, 'recall': 0.8486328125}
Model Card Contact
Feel free to reach out to me at thelong20.4@gmail.com if you have any question or suggestion.