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The 41st US president and patriarch of the Bush political dynasty oversaw the Gulf War and the end of the Cold War. Former US President George HW Bush has died at the age of 94, his son has announced. Bush, the 41st president of the United States, died on Friday, about eight months after the death of his wife, Barbara Bush. “Jeb, Neil, Marvin, Doro and I are saddened to announce that after 94 remarkable years, our dear Dad has died,” his son, former president George W Bush, said in a statement. “George H.W. Bush was a man of the highest character and the best dad a son or daughter could ask for.” Jim McGrath, spokesman for the former president, said the elder Bush died at 10:10pm Central Time (04:10 GMT), adding that funeral arrangements had yet to be scheduled. Further details about the circumstances of his death were not immediately available. US President Donald Trump paid tribute to Bush senior in a statement on Twitter, hailing his “sound judgement, common sense and unflappable leadership”. Former President Barack Obama said: “America has lost a patriot and humble servant in George Herbert Walker Bush. While our hearts are heavy today, they are also filled with gratitude.” Bush served as president from 1989 to 1993, with the successful campaign to drive Saddam Hussein from Kuwait as his most significant accomplishment. The one-term president lost the 1992 election to Democrat Bill Clinton, but he went on to see his son, George W, win the White House in 2001. Another son, Jeb, made a presidential run in 2016 but dropped out in the primaries. ‘This will not stand’ The son of a wealthy Republican US Senator, Bush served in the second world war and was elected to two terms in the US Congress in the 1960s. President Richard Nixon became Bush’s mentor, appointing him ambassador to the United Nations in 1970. While Nixon later resigned in disgrace, Bush, a savvy political survivor, became head of the CIA in 1976. He served as Ronald Reagan’s vice president for eight years, before entering the White House in 1989, pledging to make the US a “kinder, gentler” nation. {articleGUID} Less than a year after taking office, Bush sent troops to invade Panama and overthrow Manuel Noriega, a corrupt military ruler who had turned against the US. The defining moment of Bush’s presidency came in August 1990, when Iraqi tanks rolled into Kuwait. Bush famously vowed: “This will not stand, this aggression against Kuwait.” He worked closely with the UN and assembled a coalition of 32 nations to drive Iraqi forces out. American troops flooded into Saudi Arabia and established bases – a development that was later cited by Osama Bin Laden to justify attacks against the US. Once under way, the war did not last long as Iraqi forces fled Kuwait. But Bush refused to order an advance towards Baghdad, opting not to topple Saddam. In the aftermath of the war, Bush’s popularity quickly began to fade and he lost the 1992 election amid criticism of his handling of domestic affairs, including a weak economy. ‘Mixed legacy’ Joe Watkins, former aide to Bush senior, told Al Jazeera that the former president will be “remembered very fondly, very warmly around the world” because of his foreign policy achievements. Under his watch, the Berlin Wall came down, the Warsaw Pact disintegrated and the Soviet satellites fell out of orbit. The other battles he fought as president, including a war on drugs and a crusade to make American children the best educated in the world, were not so decisively won. Bill Schneider, a Washington-based political analyst, called Bush’s legacy “very mixed”. “He had one of the greatest triumphs of foreign policy in US history, which was the Gulf War. He also had one of the greatest political collapses of US history,” Schneider told Al Jazeera. “About a year and a half after he won the Gulf War, he was finished politically because the country went into a deep recession, and he didn’t seem to have a plan to get the US out of it.” After retiring from public life, Bush fulfilled a wartime pledge to one day jump out of a plane for fun and famously went skydiving on his 75th, 80th, 85th and 90th birthdays. He joined Clinton to raise funds for victims of the 2004 Asian tsunami and the 2010 Haiti earthquake. In 2011, Obama awarded Bush the highest US civilian honour, the Medal of Freedom.
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Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. The N-methyl-d-aspartate (NMDA) receptors play critical roles in synaptic plasticity, neuronal development, and excitotoxicity. Tyrosine phosphorylation of NMDA receptors by Src-family tyrosine kinases such as Fyn is implicated in synaptic plasticity. To precisely address the roles of NMDA receptor tyrosine phosphorylation, we identified Fyn-mediated phosphorylation sites on the GluR epsilon 2 (NR2B) subunit of NMDA receptors. Seven out of 25 tyrosine residues in the C-terminal cytoplasmic region of GluR epsilon 2 were phosphorylated by Fyn in vitro. Of these 7 residues, Tyr-1252, Tyr-1336, and Tyr-1472 in GluR epsilon 2 were phosphorylated in human embryonic kidney fibroblasts when co-expressed with active Fyn, and Tyr-1472 was the major phosphorylation site in this system. We then generated rabbit polyclonal antibodies specific to Tyr-1472-phosphorylated GluR epsilon 2 and showed that Tyr-1472 of GluR epsilon 2 was indeed phosphorylated in murine brain using the antibodies. Importantly, Tyr-1472 phosphorylation was greatly reduced in fyn mutant mice. Moreover, Tyr-1472 phosphorylation became evident when hippocampal long term potentiation started to be observed, and its magnitude became larger in murine brain. Finally, Tyr-1472 phosphorylation was significantly enhanced after induction of long term potentiation in the hippocampal CA1 region. These data suggest that Tyr-1472 phosphorylation of GluR epsilon 2 is important for synaptic plasticity.
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My Sex Story I necessary to be touched and where didn't matter This story went out through a conversation with a ***or about my college experiences. This one is about a seductive, manipulative classmate whatsoever I would soon get to know better. --- I was waiting on the subway to go home after class when I was approached by a cute young guy asking my name. He got it pretty mangled but I appreciated the effort as my name gets mixed ahead all time. I was a little leery at first but he told me whatsoever he was in my class and whatsoever he sits behind me ... Read more
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This invention relates in general to sewing machines and in particular to a new and useful device for sensing the thickness of the material being sewn at a stitching point. German Pat. No. 33 23 214 discloses a sewing machine that has an optoelectronic sensing device to detect changes in the position of the material. All that the prior art solution does is to give off a switching pulse when there is a transition in material positions, and it cannot determine the actual height differential of the approaching difference in thickness.
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[Epidural buprenorphine under nitrous oxide-oxygen-enflurane anesthesia in elderly patients]. The effects of epidural buprenorphine (Bn) under nitrous oxide-oxygen-enflurane (E) anesthesia in elderly patients were examined. The subjects were older than 65 years (n = 82) and scheduled for abdominal surgery. They were divided randomly into two groups according to epidural drugs used. The first group received epidural Bn 0.1-0.2 mg (group B, n = 41). The second group received epidural Bn 0.1-0.2mg + 1% lidocaine (group BL, n = 41). The enflurane concentration was 1.13% in group B, and it was significantly higher than 0.78% of group BL (P < 0.01). There was no intra-group difference in the highest systolic blood pressure during operation. The lowest systolic blood pressure during operation was 92.0 +/- 2.1 mmHg in group BL and it was significantly lower than 100.2 +/- 2.9 mmHg of group B (P < 0.05). The percentage of patients who needed vasoconstrictor drugs was 12% in group B, and it was significantly smaller than 42% of group BL (P < 0.01). On the other hand the percentage of patients who needed vasodilator drugs was 39% in group B, and it was significantly larger than 17% of group BL (P < 0.05). There was no intra-group difference in arousing time from anesthesia. Concerning the postoperative respiratory state, there was no intra-group difference in the respiratory rate, tidal volume and PaO2. But the PaCO2 value was 44.7 +/- 0.8 (mean +/- SE) mmHg in group BL, and it was significantly higher than 40.7 +/- 0.7 mmHg of group B (P < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
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Q: How many children do you have? What if you can guess that THEY are adults? This actually happened with me. As I moved into my new apartment, the society was also new to me. There is an old couple (aged above 50, I guess). I asked the elderly person (after I became a bit familiar with them) how many kids he has. And he coolly replied, "Two sons, but they are not kids anymore!" Both of us laughed but this triggered a question to my mind. His answer is valid. How many kids do you have? This means now. The answer is 'NONE' because those two sons are not kids anymore! What should be an alternative way to express this question? How many kids/children did you have? ~ but then this means they are dead How many adults do you have? ~ lol! A neutral question that works for sure... How many sons and/or daughters you have? ~ But we generally don't ask this. How many kids/children do you have? is way more common. A: As many comments have said, "kids" can refer to children of any age, and the dictionaries support that. That said, it's peculiar how the meaning of the word can shift with the right pronoun or reference. If I saw your grown sons standing in the kitchen, but didn't know who they were, I would say, "There are two people in the kitchen" – I'd never refer to them as "kids" or "children". But if I'm aware of the relationship, everything changes. In that case, I would probably say, "Your two kids are in the kitchen," even if they stand taller than me, have successful careers, and have kids of their own. Incidentally, this makes "Two sons, but they are not kids anymore!" a valid answer to your properly-worded question. Your friend wasn't correcting the wording of your question, he was simply providing further information about the ages of his children.
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Nucleocytoplasmic transport under stress conditions and its role in HSP70 chaperone systems. In eukaryotic cells, molecular trafficking between the nucleus and cytoplasm is a highly regulated process related to cellular homeostasis and cellular signaling. However, various cellular stresses induce the perturbation of conventional nucleocytoplasmic transport pathways, resulting in the nucleocytoplasmic redistribution of many functional proteins. We describe the recent insights into the mechanism and functions of nuclear import of cytosolic chaperone HSP70 under stress conditions and the cellular distribution and functions of its co-chaperones. Hikeshi mediates the nuclear import of the molecular chaperone HSP70. A few of the regulators of the HSP70 chaperone system also accumulate in the nucleus under heat stress conditions. These proteins function collaboratively to protect cells from stress-induced damage and aid in the recovery of cells from stress. Studies on the regulation of nucleocytoplasmic transport under several cellular stresses should provide new insights into the fundamental principles of protein homeostasis (proteostasis) in both compartments, the nucleus and cytoplasm.
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Description This lovely 2/2 double wide home features an open concept living room and kitchen with wood flooring throughout PLUS a dedicated dining area that is perfect for entertaining your Florida guests! With plenty of natural light, tasteful cabinets and color schemes, you are sure to feel right at home! You will enjoy the spacious master, indoor laundry, and extra shade under the carport! Did you know that you can PRE-BUY? Call us today for more details! Features * Carpet * Carport * Central A/C * Land Lease * Laundry room inside * New Buyer Incentives * Parking - 2 Car * Pet Friendly under 40 lbs * Range/Stove * Refrigerator * Shingle Roof * Shower * Tub/Shower Combo * Vinyl Siding * Walk In Closet(s) * Wood Flooring Additional Details Information provided is provided by the seller and is thought to be reliable but is not guaranteed to be accurate; you are advised to verify facts that are important to you. No warranties, expressed or implied, are provided for the data herein, or for their use or interpretation by the user. This and other listings are by sellers and posted by Newby Realty, Inc., 3310 US Hwy 301 N, Ellenton, FL 34222. Call toll free 888-847-3700 or email sales@newbyrealty.com for more information. Newby Realty endorses the Fair Housing Act and qualify each application equally. We value every person: regardless of race, color, national origin, religion, sex, familial status or handicap (disability). Newby Realty uses a national agency to consistently qualify potential customers using a written guideline including credit reports, criminal background checks and public records available. We thank you for the opportunity to serve you.
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Autodesk, Flame and the art of virtual movie-making Autodesk, which makes 3D design software for the engineering and entertainment industries, has just launched a new product called Flame Premium. Flame lets you create 3D visual effects and handle editorial finishing in television, film and commercial post-production. An earlier version of the product was used in the Philip’s Carousel commercial shown below. Flame is used in the final stage of post-production to perform tasks like color correction. However, when I talked to Autodesk’s Entertainment Industry manager Maurice Patel, he was most excited about Autodesk’s work in virtual movie-making at the pre-production and shooting stages. Virtual movie-making is the use of CG (computer-generated) characters in live action movies, like Davy Jones in Pirates of the Carribean or Gollum in Lord of the Rings. While these characters were played by live actors wearing a special suit with embedded motion capture sensors, the appearance of the CG character was only added in post-production. Virtual movie-making begins with a motion-capture camera system. Sensing devices are arranged in a room or on a soundstage to create what’s called a tracking volume; this is the area being filmed virtually. A virtual camera is controlled by an operator moving a tracking controller within the tracking volume. This defines what can be seen in the virtual viewfinder. For example, the green icon in the image below represents the virtual camera and can be manipulated to get different views in the viewfinder perspective. Some virtual camera systems like the Gamecaster® GCS3™ do not require any sensing devices and can be panned, tilted, craned and zoomed in real-time with real-life camera hardware. Autodesk’s MotionBuilder product is 3D character animation software that was originally used in games. Autodesk is now rolling out a combination of MotionBuilder and Maya, a product for creating virtual 3D environments, which work with a virtual camera system. This combination allows a director to see the CG characters created by MotionBuilder through the virtual camera’s viewfinder on a rough approximation of the background (created by Maya) on which they will appear. Actors wearing motion capture suits can also be integrated into the view. The video below shows MotionBuilder and Maya being used in this way. The director can even combine multiple takes into a single shot so that the best take from an actor can be selected and “reshot” from a new camera angle, without the actor having to repeat the take. This makes creating CG animation and visual effects shots more like a live action shoot. Eventually, it will be possible to view live actors interacting with CG actors in real time, but that’s not yet available in a commercial product. Autodesk was founded in 1982 and has 7,800 employees. The company is based in California.
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The title was originally an anthology, until the Thor was introduced and became the main feature. The numbering for this series is a bit awkward. The series ran from issue #1 to #125. Then the series was continued as Thor (1966 series) #126 to #502. In 1996, Marvel published issues #503 through 521. They are listed as Journey Into Mystery (1996 series).
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Reliability and validity of a novel haemophilia-specific self-efficacy scale. Higher self-efficacy in chronic disease patients is associated with higher development of self-management skills and increased quality-of-life. Quantification and monitoring of self-efficacy is therefore of importance. Self-efficacy in haemophilia patients has received little attention due to lack of standardized scales. To validate the novel Haemophilia-specific Self-Efficacy Scale (HSES) in haemophilia patients on prophylactic home treatment, haemophilia patients aged 1-18 years on prophylactic treatment ≥1 year were included from three Dutch Haemophilia Treatment Centres. The HSES consists of 12 items, relating to perceptions of the ability to function on a day-to-day basis with regard to patient's disease. Retest was performed in a subsample. Validity was proven by the General Self-Efficacy Scale and by the health-related quality-of-life assessment tool Haemo-QoL. Data were analysed from 53 children (response 75%), with a mean age of 9.8 years (SD 4.0). Mean total scale score of HSES was 55.5 (SD 4.7; range 38-60), with a ceiling effect of 17%. The HSES showed adequate internal consistency (Cronbach's alpha 0.72) and good test-retest reliability (Intra-Class-Correlation coefficient 0.75; P < 0.01; n = 37). The convergent validity was adequate as haemophilia-specific self-efficacy correlated significantly with general self-efficacy (r = 0.38; P < 0.01). High HSES scores correlated significantly with quality-of-life as measured by the Haemo-QoL (r = -0.42; P ≤ 0.01). The novel HSES is a reliable and valid tool to assess self-efficacy in paediatric haemophilia patients on prophylactic home treatment. High self-efficacy correlated with higher quality-of-life, further underlining the importance to standardly assess, monitor and improve self-efficacy.
{ "pile_set_name": "PubMed Abstracts" }
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Let It Loose (song) "Let It Loose" is a song by the Rolling Stones which was released as the last song on side three of their 1972 double album Exile on Main St.. Background Written by Mick Jagger and Keith Richards, “Let It Loose” is an emotional gospel blues ballad with a fervent religious feeling, the song being one of the band’s prominent forays into soul and gospel during the Exile era after Jagger had attended the services of the Reverend James Cleveland and remained deeply impressed by the singing of the gospel choir. A portion of the lyrics were lifted from the song "Man of Constant Sorrow". In an interview with Uncut magazine in April 2010, Jagger was asked about this song’s lyrical content; he replied: “I think Keith wrote that, actually. That’s a very weird, difficult song. I had a whole other set of lyrics to it, but they got lost by the wayside. I don't think that song has any semblance of meaning. It’s one of those rambling songs. I didn’t really understand what it was about, after the event.” However, in the same article Richards says “I would never take Mick’s recollection of anything seriously.” Recording Recording began in June and July 1970 at Olympic Studio in London and at Nellcote in the summer of 1971 and with overdubs added at Sunset Sound in Los Angeles in early 1972,,. With Jagger on lead vocals, backing vocals are provided by Tami Lynn, Dr. John, Clydie King, Venetta Fields, Shirley Goodman and Joe Greene. Electric rhythm guitar is performed by Keith Richards using a Leslie speaker, and lead guitar is by Mick Taylor. Bass is performed by Bill Wyman, Charlie Watts on drums, Nicky Hopkins on piano, Bobby Keys on tenor saxophone, and Jim Price plays both trombone and trumpet. Reception Russell Hall in the 20 February 2008 edition of Gibson Lifestyle describes Jagger’s strident, heart-wrenching singing on “Let It Loose” as his finest vocal achievement. Live “Let It Loose” has never been performed live by the Rolling Stones. Phish covered the song as part of their “costume” album during Festival 8 in 2009, and then again on June 30, 2012. The song was featured in Martin Scorsese’s 2006 film The Departed and appears on its soundtrack. The song was also featured in Kevin Spacey’s 2004 film Beyond the Sea, but it is not included on the soundtrack. References Category:1972 songs Category:The Rolling Stones songs Category:Songs written by Jagger/Richards Category:Song recordings produced by Jimmy Miller
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Will America Ease Sanctions on Iran to Alleviate COVID-19 Concerns? Sign up here to get Politics & Power delivered to your inbox every Monday. 1. Iran is struggling to beat the pandemic. Is it time for sanction relief? With more than 55,000 cases and around 3,500 deaths, Iran is one of the countries hardest hit by the coronavirus pandemic. A deadly mixture of government neglect, large public gatherings and an attempt to hide the outbreak made the Islamic Republic the largest coronavirus hotspot in the Middle East. Iran also faces an additional complicating factor in battling the virus’s spread: A comprehensive set of U.S.-led international sanctions, which have crippled Iran’s economy, limited many services in the country, and imposed tough restrictions on the nation’s ties with the world and its ability to trade and import goods. The sanctions, part of the Trump administration’s “maximum pressure” campaign, follow America’s decision to withdraw from the nuclear deal. They are aimed at getting the leadership in Tehran to agree to a new nuclear deal, stop ballistic activity, put an end to its meddling in neighboring countries, and deter Iran from threatening free oil tanker passage in the region and ensure the safety of U.S. allies in the Gulf. The sanctions were designed to avoid any interference in the flow of humanitarian help and medical relief, but with trade, international banking and transportation all but fully forbidden, the sanctions have made dealing with the coronavirus outbreak all the more difficult. A UN report noted that due to the sanctions, Iran cannot access respirators and personal protective equipment for healthcare workers. Which is why a new and growing school of thought in the U.S. has been calling on the administration to take a step back and allow some sanctions relief, not because Iran has evolved into a positive player in the Middle East power struggle, but as a way of easing its struggle to stop the spread of the virus and help those in need of medical treatment. “Our many disputes with the government of Iran or others should not stand in the way of actions that can materially help innocent people weather a pandemic,” wrote a group of lawmakers in aletter to Secretary of State Mike Pompeo and Treasury Secretary Steve Mnuchin. Among the signatories was Senator Bernie Sanders. Former Vice President Joe Biden, who is leading the race for the Democratic nomination, also issued astatement calling on the Trump administration to release/ease some of the sanctions. Trump has not been oblivious to the dire situation in Iran and has publicly offered American help, which Iran has rejected. But at the same time, his administration has refused to enact any relief, and in fact imposed new sanctions. Specific measures, which would allow Iran easier access to medical supplies from abroad, are being debated in the administration, but no step has been taken thus far. 2. Will the pro-Israel community fight to keep the sanctions? The possibility of putting a crack in the otherwise iron-clad sanctions regime against Iran seems to run counter to everything many in the pro-Israel advocacy world have been fighting for in past years. Israel, AIPAC and many other Jewish and pro-Israel evangelical groups had cheered Trump’s decision to break the nuclear deal and re-impose sanctions and applauded Pompeo for following up with numerous actions aimed at tightening the screws and further pressuring Tehran. Now, they’re in a tough position. Israel and many of its U.S. supporters do not wish to see the sanctions fall apart, especially since the measures have proven effective in convincing the Iranian regime that there’s a clear economic price for their regional behavior. “At the very time Iranian-backed Shi’ite militias in Iraq are killing Americans and Brits and others, this would be exactly the wrong time to be providing any kind of economic relief to the regime,” Mark Dubowitz, of the Foundation for Defense of Democracies, toldReuters. Instead, he suggested America should provide direct medical aid to Iran. But the Israeli government and AIPAC have kept a relatively low profile on the issue, avoiding any public campaign aimed at blocking sanctions relief. After all, no one wants to pick a fight with a nation struggling to save its people from a deadly pandemic. But it’s more than a PR issue. Temporary and limited sanctions relief isn’t necessarily an idea Israel would oppose, as long as it is focused on COVID-19-related measures. The issue may have to do more with Trump than with the Iranians. The president has indicated many times in the past couple of years that he’s eager to sit down with the Iranians and cut a deal. Iran, to the relief of Israeli leaders, has thus far refused. But if the pandemic leads to an opening, even a limited one, Trump may be the one seeking to widen it and turn it into an opportunity for deal-making, just like he tried to do with North Korea. 3. Endorsing Andrew Cuomo In his sober yet reassuring daily briefings, and with his warm and witty dialogues with his brother, New York governor Andrew Cuomo has developed quite a following. Cuomo fans include many who are simply looking for a sane voice to lead them through these turbulent times and others who believed that Cuomo is just what the Democrats need right now–a leader who has both the charisma and the experience to take on Donald Trump. The call torecruit Cuomo to the Democratic presidential ticket, either as the nominee or as Joe Biden’s running mate, is gaining some momentum, despite the governor’s clear rejection of any presidential aspirations right now. Joining the call to get Cuomo into the race is at least one Jewish leader: Jack Rosen, a New York businessman and Democratic donor who leads the American Jewish Congress and the American Council for World Jewry,tweeted his endorsement: “@JoeBiden made an honorable pledge to pick a woman as a running mate, something which I support strongly, but he might want to also consider @NYGovCuomo. Governor Cuomo’s leadership during the#coronavirus outbreak shows that he would be ready to serve.” 4. Mounting pressure on Bernie to bow out The Democratic primary race, for those following, is still going on. Most upcoming elections were postponed due to the coronavirus outbreak. Currently, Biden is leading in the delegate count, though both he and Sanders are still a long way from clinching the nomination. Yet for the public, the race seems to be all but over. Biden has a commanding lead in polls, and with attention diverted elsewhere, most Democrats seem resigned to the reality that the former vice president will be the one facing Trump in November. Now, it seems that this understanding is beginning to hit close to Sanders’ inner circle. According to TheWashington Post, some of Bernie’s top aides, including campaign manager Faiz Shakir, are urging the Vermont senator to call it quits now, instead of dragging out a race he has no chance of winning. Sanders, according to the report, is not ruling out this idea. 5. Is Ron Dermer on his way out? It’s been more than six years since Ron Dermer became Israel’s ambassador to Washington. In this period, he has arguably been the most influential envoy Israel has had in the American capital, spearheading Netanyahu’s huge gamble to take on the Obama administration and congressional Democrats and to steer Israeli-American ties into partisan waters. Now, the Dermer era could be coming to an end. It’s not that Dermer has done anything wrong. On the contrary, it was Netanyahu who pleaded with the ambassador in this past year to stay on. It’s only a political calculation. According to reports from the ongoing coalition negotiations in Israel, Netanyahu simply needs the Washington spot to compensate Likud ministers who might end up with no cabinet portfolio when he forms his new coalition government. Top photo: Coronavirus patients at the Imam Khomeini Hospital in Tehran, Iran
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Timing is key in drawing social security Certified financial planner Laura Lyons joins us from Meridian Trust with some important information about the timing of Social Security benefits. http://www.wbir.com/video/3616466167001/39627146001/Timing-is-key-in-drawing-social-securityhttp://download.gannett.edgesuite.net/wbir/brightcove/29913744001/201406/321/29913744001_3616527497001_th-539784e2e4b0e69b7462b684-767904724001.jpg?pubId=29913744001Timing is key in drawing social securityCertified financial planner Laura Lyons joins us from Meridian Trust with some important information about the timing of Social Security benefits.wbirNews03:48
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Summary Notwithstanding the change of Prime Minister and Home Secretary, it appears that the December 2018 Immigration White Paper is still to form the basis of future immigration policy after Brexit. The government claim to have been guided by the Migration Advisory Committee (MAC) in drawing up these proposals and, following pressure from the corporate lobby, have now asked them to review the salary levels for work permits. However, a comparison of the White Paper and the advice that they had previously commissioned from the MAC demonstrates that the government have repeatedly ignored the MAC’s warnings when it suited them and misrepresented others. In drawing up their proposals for the future immigration system of this country (a policy reform that will have far-reaching consequences), they have failed to give adequate account to… advice by the MAC that the government needs to emphasise investment in British human capital while lessening employer dependence on migration. the downsides of an increasing population repeatedly referred to by the MAC. The MAC advice against a scheme for low-skilled workers. The MAC advice in favour of a primary £30,000 salary threshold (which the government have now asked them to review) Their evidence that migration has slightly reduced employment opportunities and wages for the lower paid. The government have also remarkably claimed that the White Paper proposals would help support ‘productivity improvements’ despite the MAC report finding that the evidence was inconclusive. Introduction After the EU referendum, the MAC was commissioned to look at the impact of immigration from the EU on the UK. The MAC’s report on this was published in September 2018. Instead of simply analysing the impact of EU migration, the MAC in fact went on to make far-reaching recommendations that would affect the level of non-EU inflows. The government followed this up with publication in December 2018 of its White Paper, outlining plans for the post-Brexit immigration system. However, there are a number of contradictions between the MAC’s advice and the White Paper. This note draws attention to them. Contradiction 1 – In 2016, the MAC said it ‘consistently emphasised the need to raise British human capital and thereby lessen employer dependence on immigration’. It added that ‘the IT, engineering and health sectors invest insufficiently in UK residents’. Despite this, in the years since 2016, the government has a) removed doctors and nurses from the Tier 2 cap b) ordered a large expansion of the migration list of shortage occupations c) outlined plans to make it much easier for non-EU workers to access the UK labour market after Brexit with much lower skills levels than at present d) proposed easier access to the UK for non-UK scientists. Although it appears to have innumerable ideas on how to further widen access to the UK for workers from outside the EU, the government and businesses’ commitment to improving training opportunities (as well as wages and working conditions) for UK young people is far less clear. Contradiction 2 – The MAC report noted that ‘higher population may lead to increased congestion’ (p.13), that ‘increases in population do lead to heightened demand for public services’ (p.82), that immigration has ‘increased house prices’ (p.3) and can ‘reduce access to social housing for the UK-born’ (p.95) and that, in 2014, 70% of the public wanted a reduction in immigration levels (p.106). However, the Immigration White Paper appears entirely to overlook these negative findings and instead proposes measures that are most unlikely to reduce immigration materially, let alone to the levels promised in successive Conservative manifestos – also see our estimate of post-Brexit migration levels under the White Paper proposals (April 2019). Contradiction 3 – The MAC report called for ‘a shift towards higher skilled migration’ and specifically said: ‘For lower-skilled workers, we do not see the need for a work-related scheme with the possible exception of a seasonal agricultural workers scheme’ . Despite this, the government’s White Paper proposes (at par.26) a ‘time-limited route for temporary short-term workers’ to be able to come to the UK to take up any kind of work (and switch between jobs), including low-skilled roles for periods of 12 months at a time. Such a proposal appears to contradict directly the MAC’s advice and to pander to employers’ claims that they cannot get by without continual inflows from abroad to fill the poorly paid jobs they are offering. The MAC has previously noted that the solution to hard-to-fill jobs is to raise the pay for the job. Contradiction 4 – The MAC report concluded (p.110) that ‘there is… some evidence suggesting that migration has slightly reduced employment opportunities for the UK-born especially for the lower-skilled. Some evidence shows a small negative effect of migration on earnings at the lower end of the wage distribution and a small positive effect at the upper end’. Opening a special route for lower-skilled migration (as the Immigration White Paper does) would be very unlikely to help the government to achieve its industrial strategy aim of creating ‘greater earning power for all’. This concern is exacerbated by the previous Home Secretary’s suggestion that the salary threshold is to be below £30,000. The White Paper’s proposals would likely have a negative impact on the wages of the lowest paid and on job opportunities for the lower-skilled. They may also adversely impact training opportunities, wages and job conditions for UK workers. Contradiction 5 – On productivity, the conclusion of the MAC report is that ‘while the evidence for a more beneficial impact of high-skilled migration on productivity is not extensive, we judge it likely’ (p.110). The MAC added however that ‘the results are subject to significant uncertainty [and] the evidence on overall migration is not entirely conclusive’ (p.2). There was no compelling evidence that immigration into jobs in the UK requiring less than degree-level qualifications was enhancing of productivity and the MAC noted that some academic claims were ‘implausible’. Thus there seems no basis whatsoever for the Immigration White Paper to claim that the changes to the Tier 2 skilled route would help support ‘productivity improvements’ (p.4 of White Paper). Indeed, reducing the primary Tier 2 salary threshold from the current £30,000, and the skills threshold to A-level equivalent, together with routes to continue inflows to even lower-skilled work, is highly unlikely to boost UK productivity. Another of the White Paper’s serious shortcomings was that, despite making estimates of the impact of proposals on future inflow from the EU, it made no attempt to estimate the impact of its proposals on the future level of non-EU immigration to the UK. This is a very serious omission on a matter of great public importance. The government should explain why it failed to provide such estimates and, prior to passage of the Immigration Bill before Parliament, set in train and publish such analysis. Given that the government very clearly promised to ‘bear down on non-EU immigration’ in its 2017 election manifesto, policy proposals that would increase it would have the effect of blatantly breaking that promise. It is to be hoped that the new Home Secretary will see that the White Paper is a simple capitulation to the narrow interests of some employers and urgently instruct her officials to think again and produce something more in line with the MAC’s more sensible recommendations.
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John Whitelaw John Whitelaw may refer to: John Whitelaw (footballer), player in the 1947 Scottish League Cup Final (October) John Whitelaw (general, born 1894), Australian major general John Whitelaw (general, born 1921), Australian major general, son of the above John Whitelaw (harpsichord), American harpsichordist See also Whitelaw (surname)
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U.S. continues efforts to force Apple’s help in accessing Brooklyn drug dealer’s iPhone The U.S government said in a court filing on Friday that it will continue to appeal a ruling in the Eastern District Court of New York that has distinct similarities to the recent high-profile legal battle between Apple and the FBI. Last month a judge ruled in favor of Apple, saying the U.S government lacked the authority to use the All Writs Act, a 200-year-old law used when other legislation doesn’t apply, to compel Apple to assist in extracting data from the locked iPhone 5C of a dead terrorist. The case is similar to the fight over the iPhone of San Bernardino shooter Syed Rizwan Farook, with a few key differences. The U.S. Department of Justice isn’t asking Apple to build a specialized version of their operating system that bypasses certain security measures, but to extract data from the phone and provide it to the government in an unencrypted format. The phone in question, which belonged to a convicted drug dealer who pleaded guilty, is also running iOS 7, which was released before Apple’s operating system automatically encrypted the phone’s hard drive. Apple has previously complied with similar requests to pull data off of unencrypted phones. In a call with reporters on Friday, a lawyer for Apple who asked not to be named railed against the notion from James Comey, director of the Federal Bureau of Investigation, that these cases are about one phone, and he said that the U.S government is again trying to set a legal precedent.
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New Ideas Into certified carpet Lancaster pa Never Before Revealed Picking the appropriate floor for your house is an important decision which will influence your family’s relaxation for a very long time to Life, Death, and carpet cleaning Decatur Ga Let’s see the 2 sorts of cleaning. Dependent on the services you ultimately opt to offer when you first begin your foreclosure cleaning and trash-out company, The Basic Principles of clean storm carpet extractor That You Can Learn From Beginning Immediately A carpeting extractor is a kind of carpet cleaning system is successful by spraying water on the carpet Carpet Cleansing Acworth Ga Bleeding concerned a long-term transference the place the carpeting regularly begins to fade. There are four important sorts of luxurious carpets to bear in mind while you’re designing the The Key to Successful carpet cleaning in canton ga Bleeding involved a long-term transference where the carpeting slowly starts to fade. Therefore it’s beneficial, to receive your carpet installed by an expert so
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Effects of streptozotocin-induced diabetes on low density lipoprotein receptor expression in rat adipose tissue. Low density lipoprotein (LDL) receptors are found in most cells, including adipose cells. LDL receptors are primarily regulated by cellular cholesterol content. Insulin and insulin deficiency have been reported to have varying effects on LDL receptors in various tissues. The present study was undertaken to assess the in vivo effects of streptozotocin-induced diabetes on LDL receptor expression and cholesterol content in adipose tissue and liver, Diabetes was induced by a single dose of streptozotocin. After 3 days, some animals were treated with insulin, and all animals were killed 10 days after induction of diabetes. Compared to control rats, 10 days of diabetes caused a decrease in adipose cell size and cellular unesterified cholesterol and cholesteryl esters, and insulin treatment returned these towards normal. No changes were observed in hepatic lipid content with diabetes or insulin treatment. Diabetes was associated with an approximately 50% reduction in immunoreactive LDL receptors in adipose cells (P < 0.01) that was returned to normal with insulin treatment. The levels of LDL receptor mRNA decreased approximately 80% (P < 0.001) in adipose cells isolated from streptozotocin-induced diabetic rats and returned to normal with insulin treatment. Hepatic LDL receptors and mRNA levels were unaffected by diabetes or insulin treatment. In conclusion, diabetes decreased LDL receptor expression in adipose cells while total cellular cholesterol content also declined.
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Deletion of the short arm of chromosome 3 in breast tumors. Deletions in the short arm of chromosome 3 have long been known to be common in many tumor types, including carcinomas of the lung and kidney. Small interstitial deletions of the proximal-central region of 3p, with band 3p14 as a minimal common deleted segment, have recently been shown to occur in as many as 10% of carcinomas of the breast, often as the only chromosomal change. Seemingly identical deletions may also be found in the epithelial cells of mixed-lineage benign tumors of the breast and even in diffuse proliferative breast disease, a disorder that would not normally be accepted as neoplastic, but never in completely normal breast tissue. The cytogenetic evidence therefore indicates that the putative tumor suppressor gene deleted from 3p14 influences cellular proliferation; evidently, its loss is often not sufficient for a fully malignant phenotype to emerge. The first information about FHIT, a candidate suppressor gene recently identified in the FRA3B fragile site in 3p14 and found to be abnormal or lost in a high percentage of carcinomas of various organs, including breast, is compatible with such a general proliferation-regulating role.
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Admin login A Critique of Generative Class Theories of Environmentalism and of the Labour–Environmentalist Relationship Author Year published Metadata Abstract Relations between the labour and environmental movements are believed to be prone to conflict stemming from the different class bases of the two movements. The generative class theories of the environmental movement and the labour-environmentalist relationship (LER) implicit in this belief are examined against research on the sociology of new social movements and cases of labour-environmentalist interaction, and rejected. Nonetheless, class in a dimensional sense remains important in terms of circumscribing social actors' abilities to shape, and respond to, environmental and economic change; rejection of generative class theories of the LER should not entail espousal of an 'environmentalism without class'.
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John Bel Edwards’ opponents should probably hope that January is the cruelest month and things will get better in the election by October. The incumbent governor is a Democrat in a Republican state. The virtues — and sometimes the pitfalls — of seeking reelection have been on display as Edwards formally announced his candidacy via an online video release. Typically in politics, this is a way to avoid pesky questions from reporters and others, but the governor can hardly be blamed in that regard. At one time, a fly around the state’s major media markets over a couple of days was standard practice. Today, the use of digital platforms for such announcements is ubiquitous. And the governor does not appear to be hiding from questions: He answered them for an hour at the Press Club of Baton Rouge and then kept a steady pace of appearances around the state, particularly where he can underline economic development “wins” for the state. These included the big DXC Technologies location on Poydras Street in vote-rich New Orleans. It’s better to be an incumbent with a growing economy. Just ask former Gov. Bobby Jindal, who similarly plugged every new plant or other business victory, sometimes several times, before his 2011 reelection victory. The governor’s fluency in the discussions of government is an asset but can also be a political liability, too. He sometimes verges on the wonkish, offhandedly referring once to the teacher pay raises he wants — a big populist issue — as going directly to school employees through Level 3 of the MFP. Say what? The MFP, which might as well be called the Mysterious Funding Process, is one of the abiding mysteries in the State Capitol. Officially known as the Minimum Foundation Program, it's the state-local funding formula for schools — and incredibly complex. Who knew there was a Level 3? Well, there apparently is, and Edwards’ casual references to these and other programs suggest difficulties for his challengers. Edwards is a formidable debater, and government is the subject about which he knows a great deal after two terms in the state House and four years as governor. So far, there are two challengers, Baton Rouge businessman Eddie Rispone and North Louisiana member of Congress Ralph Abraham. Both are relatively little-known around the state and have a hill to climb in terms of name recognition. Abraham drew some criticism when The Advocate reported that he had quietly backed away from his much-publicized first-term pledge not to take his pay, but to give it to good causes. Abraham apparently does donate generously, but by changing his position without sufficient care for appearances — he was still taking credit for the original pledge on his website — a clumsiness about politics was suggested to the Republican donors he is courting to fund his campaign. When Rispone and Abraham do raise their profiles, though, they will have to have something relevant to say. Maybe talk-radio slogans will work for a while, but some coherent argument about what the challengers want to do in office will then be needed. Edwards’ sophisticated arguments about government agencies and programs will have to be countered with something other than platitudes. All this doesn’t mean John Bel Edwards is in high cotton, as they might say in Abraham’s Mississippi Delta district. But it does suggest that he had a good January — and that his Republican opposition has not yet grappled effectively with its challenges. Email Lanny Keller at lkeller@theadvocate.com.
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Q: Javascript - closure in anonymous function referencing a global function using arguments - how do i use preventDefault? In the following code, where would I use preventDefault? I have been testing it to make it work but have not found a good way to cancel the default submit action. Which function needs to be capture the event object? Here is the code: f_name = 'someFunc' ; f_args(1,2,3) ; if(element.addEventListener) { element.addEventListener('submit',(function(name,args,element) { return function() { window[name].apply(element,args) ; } })(f_name,f_args,element) ,false) ; } A: f_name = 'someFunc'; f_args = [1, 2, 3]; if (element.addEventListener) { element.addEventListener('submit', (function (name, args, element) { return function (e) { // here e.preventDefault(); window[name].apply(element, args); }; })(f_name, f_args, element), false); }
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If this is your first visit, be sure to check out the Forum Rules by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. HO, look who is talking, a senior member. If I really use my ability, I will come to the root of your computer and take the BT3. "risking a kick" of what? of the WEB? or lose my internet connection? but the bad news I have recently read is that backtrack (and the related distros) is no longer legal in germany. YOU're an idiot, because supmodos can now track you, because fbi is monitoring this forums and others, and it's because of babies assholes like you that one day this forum will end.......... and btw i think you must think a little bit more before saying you will hack one of us..........just don't forget who you are talking to, we are not babies hackers, one day you may have pbs to talk like that....you can risk more....much more...than loosing your connection....destructive hacking is efficient...even if i don't practice it because it's illegal .........; purehate, again im agree with you, me too i wish we find a solution for kicking off this kind of script kiddies & l33tH4X0rs sorry about the delay in getting back to you, COX killed my internet for seeding linux distros (but not BT3!!!) anyways, no i'm using a pcmcia card withthe tiacx100 chipset, i think i'm just going to using isomaster tear apart the usr.lzm and copy and paste the scripts in there rightful place and then recompile the whole iso and reburn, half to get some more cd-r's but if anyone knows an easier way or if anyone with the acx cards has already sent in a completed report, go ahead and tell me cause i'm starting to feel like a failure/slacker. peace yeah so i tried my iso-method and that failed miserably and the only thing i manage to accomplish was a very efficent method for wasting cd-r's, upon boot up it said "created too many symbolic links" and promptly crashed, i also tried an irqpoll like "shamen..." said and as far as the computer can discern the hardware is there. i'm gonna burn another pure aka unmangled by me iso and try another route as i just installed a mini pci atheros ar 5212 card today and updated the madwifi drivers on my harddrive install of BT2. after doing that i noticed that there is a possible dependecy on the wlan scripts that cause the firmware to be flashed on boot up instead of using the "cd /usr/src/driver/acx100 && insmod acx.ko && cd && macchanger -a wlan0 && ifconfig wlan0 up" script i've been using. as always if i've left any information that anyone would need to help me, or if someone has figured out the problem already, drop me a line. take care all. peace I have common NIc adapter. I have no Wireless and it's quite enough. it too fast and not limited as you consider. I only need linux and internet connection to send raw packet around my switch(in my neighbourhood) and I can caught any input/output traffic(as I remember it's sniffing, olso snoofing it's too possible isn't it?). and why WireLess adapter is so well-known subject in your forum? have someone any refer to me why it is ? /sorry for my poor enlish ; simple report why wireless is most popular subject? what can you do using this one better then simple nic adapter? Nothing, but wireless is for the most part hidden. You don't have to have physical access to a network to do things to it. Of course, if you really wanted to have some fun, go to Wal-Mart late at night and ask the greeter if they could help you find trashbags, roll of carpet, rope, quicklime, clorox and a shovel. See if they give you any strange looks. --Streaker69 why do I need pysical access? expect them I can reach any information which is already shared by my nightboor. if it is not as I want then he/or/she will make me force to use some properlly exploit which makes his job excellently . or I will need some sniffer for ex:ettercap and then another time I will able to establish connection between us. what is different amoung this two adapter? wireless can do everything same as common nic and it's all. simple report why wireless is most popular subject? what can you do using this one better then simple nic adapter? When pentesting, you don't always have physical access to the target network, and wireless is generally the only point of entry available to you Originally Posted by vsotolkanachinaietsa why do I need pysical access? expect them I can reach any information which is already shared by my nightboor. if it is not as I want then he/or/she will make me force to use some properlly exploit which makes his job excellently . or I will need some sniffer for ex:ettercap and then another time I will able to establish connection between us. what is different amoung this two adapter? wireless can do everything same as common nic and it's all. This thread is not the place for this discussion, please start a thread in the general IT area and people will be happy to answer your questions. I would be able to help if you guys need another to test. I have a orinoco gold - atheros, senao 2511 -prism, and 1 laptop with 3945 intel and another i believe it has the intel 2200(been a while since i have used it but i think its the 2200).
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I’ve had thousands of dollars in credit card debt since 1997. I remember applying for a job in March of 2001 which I calculated would help me erase my credit card debt in about twelve months. I didn’t get that job. Nobody got that job, in fact, the entire web design sector was crashing, and I had just moved to Seattle. Almost two years ago on this very website I declared that I would be free of credit card debt six months later. That didn’t happen, either. I admit that this problem is almost entirely my fault, even though circumstances beyond my control have made the problem worse, like a 10% pay cut from last Spring that still hasn’t been fully restored (even though we’ve hired two new people). But in January of 2010, I decided (again) that enough was enough, and I started posting regular debt updates, and limited myself to spending only $100 a week. I thought it would be plenty, but on weeks that required gasoline or a haircut or car maintenance, well, it didn’t always work out as planned. On the upside, I have more than one source of income, and I’ve been able to maintain a regular schedule of paying about $1,300 a month toward that debt. It hasn’t been a joy funneling every dollar I could toward the ghost of debt that has been haunting me for thirteen years. We missed an entire growing season in the backyard because we didn’t have the money to pay someone to fix the faucet, to say nothing of every other home improvement project that was put on hold. Thanks to the obligation to post regular, detailed updates, I found places I could be saving more money, and on May 7th, I was able to completely pay off one of my two credit cards. Now here I am, on the cusp of paying off the second, and last, credit card that I ever hope to carry a balance on. No, I really mean it this time. I got paid today, and between that and the extra money from side jobs, I am able to bring the balance to just a couple hundred dollars. Now, even if I double my weekly budget for myself, and ignoring side jobs and the restoration of my proper salary, I’m still going to have $1,100 a month that I don’t owe to anybody. I can’t stress this enough: this is completely new territory for me. First, of course, I’m going to throw a party. There will be good wine and delicious snacks. You can’t talk me out of that. After the party, though, I’m conflicted about how best to deal with the extra income. We still have car loans and a mortgage, but I don’t feel a strong compulsion to pay those down faster than is scheduled. I know that most of our very smart readers will encourage me to start saving toward a three- or six-month emergency buffer. When I look at the three-month number of $12,820, I feel the same dread I used to feel when my credit card debt totaled a similar number. Suffice it to say that I’ve never saved even 10% of that amount in my life, and I’m shocked that we go through that many expenses in just three months, but we do. At present, mostly because of my previous credit card payments, my wife and I put 10% of our leftover income into a joint savings account. If we kept it to 10%, we’d meet our three-month buffer in twenty-six months. If we bumped it up to 50%, we’d meet the same goal in five months, and we’d have about $200 each for weekly expenses. In reality, we’ll probably settle on something higher than 25% but lower than 50%. There are still all those household projects to take care of, vet bills, maybe some occasional new clothes, etc. All of the above assumes that both of us want to stay at our current jobs, earning the same salaries, which isn’t necessarily true. We both have strong creative urges that are better fulfilled at the kind of projects you find outside of offices, and if we could still live without fear of homelessness, either one of us might be persuaded to seek a job with a lower salary and fewer hours and/or brain requirements, so that we might have more opportunities to pursue those creative projects. If you sympathize with that, or even if you don’t, I’d love to hear your story in the comments below. Somehow over the past several years, I’ve been increasingly finding myself in the position of an entrepreneur. Throughout my life, I have been a bit of a self-starter with the ability to inspire others to join my causes, whatever they may be. I’ve never considered myself an entrepreneur, however. I never thought I’d be using my creative tendencies to run and manage a business. Frankly, I’m not very good at it. I’m quite disorganized, and competing priorities always seem to be problems. And if my history of dead-end projects is any indication, while I may be a self-starter, I’m not always a self-finisher. To me, “entrepreneur” was a bad word, signaling a person whose specialty was business rather than the industry in which the business falls. Nevertheless, here I am, an accidental entrepreneur running and trying to manage a successful business. I don’t admire many entrepreneurs, but I am a fan of Aaron Patzer — at least what I know of him from his public persona and our interviews on the Consumerism Commentary Podcast. Aaron created the popular web-based personal finance management and budgeting software Mint.com, which was recently purchased by software behemoth Intuit, the makers of Quicken. This entrepreneur is a lecturer with The Founder Institute, a membership organization designed to support budding business-starters. He also recently wrote an article for CNN describing how the institute developed a test that can supposedly predict the success rate of an individual as an entrepreneur. The test is based on research that indicates that success is not correlated to traditional metrics like IQ, teamwork, and planning. Instead, the best entrepreneurs tend to be spontaneous, appreciative of aesthetics, passionate about art and literature, and older. Not everyone is destined to succeed as an entrepreneur, and that’s not a bad thing. A lot of people — and the programs they offer for sale — tend to treat entrepreneurship as the Holy Grail of personal finance or wealth-building, with complete control of your own financial destiny and the ability to create wealth rather quickly compared to buying and holding stocks for decades in order to become “rich.” But this lifestyle is not for everyone, and not everyone is interested in taking the entrepreneur’s path. If you take a look at our best online savings accounts page, you’ll notice EverBank resting in the number two slot. In terms of true online banking institutions, this bank is worth mentioning because EverBank offers a variety of money market, checking, and CD accounts that the first-listed bank, SmartyPig, does not have. To increase their appeal even more, EverBank has just announced a $75 cash promotion for anyone that signs up for a new money market and checking account. The bonus is split between the MMA, which offers a $50 bonus, and the checking account, which offers a $25 bonus. Here are the details on each of the two promotions. As of September 20th, 2010, the EverBank $75 Cash Bonus Promotion has expired. Yield Pledge Money Market Account – EverBank’s Yield Pledge Money Market Account currently sports a first-year interest yield of 1.51% APY, which includes a three month bonus interest rate of 2.25%. Every following year, customers will earn a 1.26% APY. A new customer who opens a new account and makes a $20,000 deposit will receive a $50 bonus on the fifth month’s statement. In order to receive the bonus, the initial deposit cannot be withdrawn before the fifth month. If your account’s balance drops below $5,000 in any month, you will be charged an $8.95 monthly maintenance fee. FreeNet Checking Account – High-yield checking accounts are tough to come by these days and EverBank offers one of the best you’ll find. Similar to the bank’s MMA, the FreeNet Checking Account has a bonus APY of 2.25% for the first three months, then a tiered interest rate in the following amounts: $100,000 and up: 1.26% APY $50,000 to $100,000: 1.20% APY $25,000 to $50,000: 1.16% APY $10,000 to $25,000: 0.70% APY Less than $10,000: 0.51% APY In order to receive the $25 bonus, customers must open a new account with a minimum of $10,000. The bank will pay the bonus on the fifth monthly statement. There is no monthly fee to maintain your FreeNet Checking Account regardless of the balance. A bonus of $75 on top of a $30,000 deposit might not be enough to make you leave your current banking institution. However, if you’ve been considering or have just heard of EverBank, now is the time to take advantage. To sign-up for this limited-time offer visit EverBank’s Official Website. This is a guest article by Ramit Sethi, author of the best-selling personal finance book, I Will Teach You to Be Rich. He recently launched a new program, Earn1k, to help people earn more money on the side. To get a free mini-course on earning more, sign up here. Ramit will also be our guest ... Continue reading this article… The 2009 economic stimulus, usually called the Making Work Pay tax credit, provided slightly bigger paychecks for the middle class throughout part of 2009 and all of 2010. This benefit is in danger of expiring if Congress does not act to extend or renew the credit. This stimulus took a different form than those previous. ... Continue reading this article… You’ve probably seen this sign hanging up in a shop or office: Rule 1: The customer is always right. Rule 2: If the customer is wrong, see Rule 1. This is not always right. I’ve had a lot of jobs I’ve been out of school and in the working world for thirteen years. That’s not ... Continue reading this article… How often do you visit the dentist for preventive care? Since graduating college, I’ve been getting regular check-ups and cleanings twice each year. I’ve seen the results of neglect, and I have no desire to lose my teeth any time soon. I’ve also seen results of bad dental work, so it’s imperative not only to ... Continue reading this article… On today’s episode of the Consumerism Commentary Podcast, Tom Dziubek talks to Richard Rosso, CFP and financial consultant at Charles Schwab. Richard discusses his advice on how to prevent a natural disaster from becoming a financial disaster and offers up many tips, including how to make sure you have the proper insurance coverage, taking inventory ... Continue reading this article… Gas prices are on their way back up again. When the economy tumbled in the past few years, gas prices dropped from their highs, but they are now increasing fairly steadily. It’s hard to imagine where the price of gas will be just one year from now, but it makes sense to continue preparing for ... Continue reading this article… I used to answer customer service calls for Bank of America, one of the nation’s biggest banks. Granted, I was near the bottom of the totem pole, but they generally treated everybody with respect there (I was in Washington State, your mileage may vary), and they wanted us to be able to give customers informed ... Continue reading this article… Several years ago, I decided to take advantage of an opportunity to pursue a master’s degree in business. I had been working in finance for a while, and as someone who believes in lifelong education, I figured it wouldn’t hurt to obtain an MBA. I took the relatively unpopular route of pursuing a degree where ... Continue reading this article… After some false starts, Congress has passed a bill to renew the extension to federal unemployment benefits. Federal benefits begin when state benefits end. With the extension in effect, jobless individuals qualify for benefits for a total of 99 weeks. The most recent extension expired on June 2, and this new bill extends the deadline ... Continue reading this article… Updated: The media are calling the new Wall Street Reform Law, recently signed by President Obama, the most significant reform of the financial industry since the Great Depression. It looks to tighten the reins on a industry that helped cause the recent recession by requiring the Federal Reserve to create and enforce regulations on the ... Continue reading this article… Editor’s Note: Thank you for your interest, this offer expired and is no longer available. One of the best cash back credit cards available today, the True® Earnings Card from Costco and American Express can earn cardholders an immense amount of rewards, just for everyday purchases. Now, with a $25 cash back bonus opportunity, just ... Continue reading this article… I enjoy a good glass of wine, but I don’t know how to find one. I haven’t been buying wine long enough to have memorized a group of “go to” bottles. I probably made the mistake of buying Bolla Pinot Noir three times before I finally learned that I don’t like it. Between my unreliable ... Continue reading this article… Here’s the message conservative lenders are sending: Don’t have a baby if you want to qualify for a mortgage. On maternity leave or paternity leave, it’s common for a family’s income to drop. If income during the leave is classified as disability income, mortgages look at this income as temporary, and they often don’t consider ... Continue reading this article… I’m not a skilled investor, particularly when it comes to short-term prognostication, and my long-term track record has yet to be established considering my first investing decision was less than ten years ago. I don’t invest in many individual stocks. My 401(k) includes company stock as part of my employer’s matching contribution, and I opted ... Continue reading this article… Today’s episode of the Consumerism Commentary Podcast features two interviews. In the first segment, Tom Dziubek speaks with Aaron Patzer, founder of Mint and Rob Garcia, Director of Product Strategy at Lending Club about Mint’s new “Goals” feature and their related partnership with Lending Club. Then, Tom talks with Consumerism Commentary founder Flexo about different ... Continue reading this article… Flexo posted a good review of the major changes in the Wall Street Reform bill that passed through Congress yesterday, and mentioned that it will be some time before we know exactly how the regulations which are now possible will be written. But there are some reasonable guesses we can make, and I thought it ... Continue reading this article… About Luke Landes Luke Landes founded Consumerism Commentary in 2003 and has been building online communities since 1990. Luke has contributed to PC World Magazine, US News, Forbes, and other publications. Read more about Luke and about Consumerism Commentary. Content on Consumerism Commentary is for entertainment purposes only. Rates and offers from advertisers shown on this website may change without notice; please visit referenced sites for current information. Per FTC guidelines, this website may be compensated by companies mentioned through advertising, affiliate programs or otherwise. Advertiser Disclosure: Many of the savings offers appearing on this site are from advertisers from which this website receives compensation for being listed here. This compensation may impact how and where products appear on this site (including, for example, the order in which they appear). These offers do not represent all deposit accounts available.
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535 U.S. 1011 MILLERv.FRANCIS, WARDEN. No. 01-9212. Supreme Court of the United States. April 15, 2002. 1 C. A. 6th Cir. Certiorari denied. Reported below: 269 F. 3d 609.
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5 Movers near Round Rock, TX Best Round Rock Movers Army Guys Moving. Hire a Veteran and Team! BIG MOVES / small moves...One or more item moves. We are local moving contractors for local stores with plenty of references. Trusted Prompt Professional Experienced movers Packing Loading Labor Unloading View more Moving is exhausting. If you have a full-time job you might just find yourself in a position where you need to take a day or two off work just to organize, pack, clean, move, unpack, and organize again. I created No Sweat Moving Helpers, because I believe moving should be a milestone in life you get to enjoy. View more Charles Family Services, Has Many great Reviews, We are affordable and professional. We provide Professional services such as: -Power Washing Sidewalks, FencDriveways, Houses and Fences -Fence repair or replacement For Stone, Chain link, and Privacy Fence -Patio whether it is Concrete Flagstone or Wooden… View more Round Rock, TX Garbage Removal •Moving Recent Reviews 5 3 months ago I was referred to No Sweat Movers by a friend who had highly recommended them. From the start, Nick, the owner got everything squared away and scheduled for me with about a week's notice. Nick gave me a call to let me know they were on their way the morning of the move and showed up a few minutes early. Good experience. We needed to move a lot of boxes with clothes and Round Rock Moving did it for 6 hours. Showed up on time, packed all stuff, were polite, worked very quickly and charged us exactly what they had said. Need Moving: Just a few things. Type of property: One-story house. Relocation distance: 5 - 10 miles. Additional services: Not specified. Number of boxes: No boxes. Stairs at primary location: No, the move is on the ground floor. Stairs at destination location: No, the move is on the ground floor. Stage of hiring process: Need some more information before hiring. Schedule of relocation: I'm flexible. Additional info: It's just a elliptical.
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Ketamin hy vọng mới cho bệnh nhân trầm cảm Trầm cảm là căn bệnh dẫn đến trào lưu tự hại Hiện nhiều người trẻ trên thế giới đang thực hiện một trào lưu đáng sợ gọi là “self-harm”, còn gọi là "tự hại", bắt nguồn từ chứng bệnh trầm cảm. Theo thống kê, cứ 10 người ở độ tuổi từ 11 - 25 thì có 1 người có xu hướng tự hại. Cắt tay, tự cứa thân thể dẫn đến ứa máu và cuối cùng là tự sát là những hành động tự hại, một biểu hiện rối loạn về hành vi đi kèm với căn bệnh rối loạn cảm xúc mang tên trầm cảm. Sang chấn tâm lý, trạng thái ức chế cảm xúc kéo dài và thiếu thốn tình cảm là nguyên nhân chủ yếu của hội chứng này. Khi những hành động tự hại không thể tiếp tục giúp giải tỏa tâm lý, người bệnh sẽ tự sát. Trong 80% trường hợp tự sát, nạn nhân đã từng tự hại trong khoảng thời gian một năm trước đó. Đáng sợ hơn, hội chứng này đã bắt đầu xuất hiện ngay cả ở trẻ em chỉ mới 7 tuổi hay những người vốn có cuộc sống rất thành công. Tuy nhiên, vì không biểu hiện ra bên ngoài, rất khó để người trầm cảm có thể nhận được sự giúp đỡ. Điều cần thiết nhất là gia đình, bạn bè quan tâm, dành nhiều thời gian cho họ hơn trong cuộc sống. Ketamin Hy vọng mới cho bệnh nhân trầm cảm Hiện nay, có nhiều loại thuốc được thử nghiệm để giúp bệnh nhân đẩy lùi căn bệnh trầm cảm, trong đó có Ketamine - loại thuốc vốn dùng để gây mê. Ketamine là "liệu pháp mang tính đột phá" trong việc điều trị những bệnh nhân có khuynh hướng tự sát. Thuốc có thể được hấp thụ tốt qua đường tĩnh mạch hoặc tiêm dưới da và có hiệu lực khoảng 4 giờ sau khi dùng. Thử nghiệm được các bác sỹ tại Đại học New South Wales (Australia) tiến hành trên 16 tình nguyện viên cao tuổi không có phản ứng với các phương pháp điều trị khác. Sau 6 tháng, gần nửa số bệnh nhân không còn triệu chứng trầm cảm - một tỷ lệ được coi là khá khả quan. Các chuyên gia sức khỏe cho biết trầm cảm là một bệnh lý nghiêm trọng, ảnh hưởng tới khoảng 300 triệu người trên thế giới. Nếu không được điều trị, bệnh không chỉ ảnh hưởng lớn đến đời sống mà còn dẫn đến nguy cơ tự tử. Nhiều nghiên cứu dự báo đến năm 2020, trầm cảm sẽ là căn bệnh xếp hạng 2 trong số những căn bệnh phổ biến toàn cầu. Trực tiếp tư vấn và điều trị nghiện rượu, nghiện heroin, các rối loạn tâm thần do sử dụng cần sa, ketamin, ma túy đá (nghiện đá, ngáo đá), thuốc lắc. Tiến sĩ Trần thị Hồng Thu 0988 079 038 - 0916 316 028
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U.S. military formally ends mission in Iraq Khalid Mohammed / Associated Press The U.S. and Iraqi flags and the U.S. Forces-Iraq colors are seen before they are carried in during ceremonies in Baghdad marking the end of U.S. military mission in Iraq. After nearly nine years, 4,500 American dead, 32,000 wounded and more than $800 billion, U.S. officials formally shut down a conflict that U.S. Defense Secretary Leon E. Panetta said was worth the price in blood and money, as it set Iraq on a path to democracy. The U.S. and Iraqi flags and the U.S. Forces-Iraq colors are seen before they are carried in during ceremonies in Baghdad marking the end of U.S. military mission in Iraq. After nearly nine years, 4,500 American dead, 32,000 wounded and more than $800 billion, U.S. officials formally shut down a conflict that U.S. Defense Secretary Leon E. Panetta said was worth the price in blood and money, as it set Iraq on a path to democracy. (Khalid Mohammed / Associated Press)
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At the Brexit Party campaign launch, Nigel Farage claimed that UKIP had ‘disproportionately hurt the Labour party in the 2015 general election’ and that the Brexit Party would do the same again in 2019. My colleagues on the British Election Study have shown that Farage is wrong: the Brexit Party – and UKIP before it – mainly draws voters away from the Conservatives, not Labour. The Conservatives won a majority in 2015 despite UKIP, not because of them. Likewise, the Conservatives lost their majority in 2017 despite the UKIP collapse, not because of it. That UKIP and the Brexit Party primarily draw their support from the Conservatives is not a new finding – Geoff Evans and Jon Mellon first pointed it out in 2015. Why then, does this idea continue to persist? One possibility is that politicians, journalists, canvassers, and ordinary citizens might talk to Labour-Leave voters and find that they are more likely defect to the Brexit Party than Conservative-Leave voters. But this doesn’t mean that the Brexit Party is more of a threat to Labour, because both of these things can be true at the same time: Labour-Leavers are more likely to defect to the Brexit Party than Conservative-Leavers. More Conservative voters are likely to defect to the Brexit Party than Labour voters. The reason that both of these things can be true at the same time is simply that there are lots more Conservative-Leave voters out there than Labour-Leave voters: the British Election Study data suggests the proportion of 2017 Labour voters who voted Leave was about 31% (and this doesn’t vary that much between constituencies), while about 73% of 2017 Conservatives voted Leave. Failing to take this ‘base rate’ into account is a very common mistake that people make when reasoning about probability – and the question of whether the Brexit Party is a threat to the Conservatives or Labour is, at its core, a question about probability. People are not making this mistake because they are stupid. As Professor Sir David Spiegelhalter – one of the top statisticians in the country – has said, people find probability unintuitive and difficult because it is unintuitive and difficult! Fortunately, however, statisticians have learned that people find probability much easier to understand when you express things in terms of expected frequencies rather than as probabilities and percentages. So, for the remainder of this blog I’m going to do just that, and try and explain why the Brexit Party is more of threat to the Conservatives than Labour, even if Labour-Leavers are more likely to defect to the Brexit Party. Imagine a seat with 100 voters. This seat is an ultra-marginal and last election, 51 people voted Labour and 49 voted Conservative. Then, let’s say about 35% of Labour voters in this seat voted Leave in the referendum, which means there are 18 Labour-Leavers. And let’s say 70% of Conservatives voted Leave, which means there are 34 Conservative-Leavers in our seat. This means that, like the country as a whole, this seat voted 52 Leave to 48 Remain in the referendum. To make the easier to follow, I’ve turned these numbers into a chart, which shows Leavers as solid circles and Remainers as shaded circles. Now let’s say the Brexit Party is better at recruiting Labour-Leavers than Conservative-Leavers. In my scenario, one in two Labour-Leavers defect to the Brexit Party but only one in three Conservative-Leavers do the same. With 18 Labour-Leavers that means nine people defect to the Brexit Party from Labour, while from 34 Conservative-Leavers 11 defect. The end result is that Labour win the seat again, 42 votes to 38 – an increase in the size of their majority. At this stage I should point out that these numbers are very generous to the ‘Brexit Party is a threat to Labour’ argument. At the 2019 European Parliament election, the British Election Study data suggest that Conservative-Leavers were more likely to defect to the Brexit Party than Labour-Leavers. This has changed since Boris Johnson (who was very popular with Brexit Party voters) became Prime Minister. More recent survey data suggests that Labour-Leavers might now be more likely to defect to the Brexit Party, but at a rate of about one in four, compared to one in five Conservative-Leavers – considerably less than the rate of defection in my example. Now let’s imagine another seat, again an ultra-marginal. However, this one has a Conservative incumbent who won 51 votes compared to Labour’s 49. To keep things simple I’ll keep the proportions voting Leave and Remain the same as last time. 35% of Labour voters voting Leave is 17 people, while 70% of Conservatives voting Leave is 36 people. In total, this seat is slightly more Leave-y than my other seat, with 53 people supporting Leave and 47 supporting Remain. Again one in two Labour-Leavers defect to the Brexit Party, which means nine defectors, and one in three Conservative-Leavers defect, which is 12 people. The end result of all this switching is that – despite the overall support for Leave being higher than my previous example – Labour wins the seat off the Conservatives, 40 votes to 39. Of course, this isn’t to say that the Brexit Party wouldn’t pose a threat to Labour if they recruit enough Labour-Leave voters. However, there are more than twice as many Conservative-Leave voters as there are Labour-Leave voters. So to pose a threat to Labour rather than the Conservatives, the Brexit Party would need to recruit Labour-Leavers at more than twice the rate they recruit Conservative-Leavers. The current polls suggest the Brexit Party are a long way from achieving that. Conservative-Leavers and Labour-Leavers seem to be defecting at similar rates – the net result being that more than twice as many Conservatives are switching to the Brexit Party compared to Labour voters. So to cut a long story short, if you’re a politician, journalist, canvasser, or just an ordinary citizen: you may well talk to Labour-Leavers and find that more of them are defecting to the Brexit Party than Conservative-Leavers. But you need to remember that there are many more Conservative-Leavers out there, which is why the Brexit Party poses a threat to the Conservatives. By Chris Prosser, Presidential Fellow at the University of Manchester and Co-Investigator of the British Election Study
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Age Requirement for Missionary Service Lowered By Heather Whittle Wrigley Church News and Events 10491_000_051 At the opening of the 182nd Semiannual General Conference, President Thomas S. Monson announced that, effective immediately, men may begin serving missions at age 18 and women at age 19. Later, at a press conference, Elder Russell M. Nelson of the Quorum of the Twelve Apostles emphasized that the change is an option: “Young men and young women should not begin their service before they are ready spiritually and temporally,” he said. Such things as schooling, family circumstances, and health still remain important considerations for the timing of missionary service. Elder Jeffrey R. Holland of the Quorum of the Twelve Apostles explained that prospective missionaries may be recommended by their bishop and stake president for full-time service 120 days prior to their 18th birthday or to their availability date. Young men may enter the missionary training center (MTC) after graduating from high school or its equivalent and reaching 18 years of age. Women may enter after their 19th birthday. Prospective missionaries are being asked to enhance their pre-mission preparation prior to their time at the MTC. “God is hastening His work,” Elder Holland said. “And He needs more and more willing and worthy missionaries to spread the light and the truth and the hope and the salvation of the gospel of Jesus Christ to an often dark and fearful world.” Elder Holland said it is likely that additional missions will be created. To help accommodate the anticipated increase in missionaries in missions around the world, time spent at the MTCs will be reduced by one-third for all missionaries. A recently implemented 12-week training course being administered in the mission field will help further prepare missionaries.
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Masters champion Mark Allen delights fans in Antrim as he completes a maximum 147 at his homecoming event in Northern Ireland. Allen beat Kyren Wilson 10-7 in January's final, becoming the first Northern Irishman to win one of snooker's three major titles since Dennis Taylor in 1987. After a opening shot slip-up from local council mayor Paul Hamill, Allen went on to hit a 147 in front of a packed Antrim Forum.
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Antitumor pathway of Rhizoma Paridis Saponins based on the metabolic regulatory network alterations in H22 hepatocarcinoma mice. Rhizoma Paridis Saponins (RPS), which is the effective part of Rhizoma Paridis, showed strong anti-lung cancer and anti-hepatocarcinoma activities. In this research, a gas chromatography/mass spectrometry (GC/MS) method was developed and validated for the metabolic profiling of RPS intervention in H22 hepatocarcinoma mice. Data were analyzed with partial least-squares discrimination analysis (PLS-DA). As a result, RPS displayed different pathway to decrease energy production of the mice. For the normal mice, RPS significantly decreased the concentration of lipid, glycerate, succinate and lactate, but increased glucose and valine levels. All these indicated that RPS inhibited glucose and valine to transform ketones which participated in the ATP production. For the H22 cancer mice, RPS increased the concentration of lipid and glycerate, but significantly decreased glucose, glycine and alanine levels in the serum. This phenomenon indicated that RPS inhibited the oxidation of fatty acids pathway and the gluconeogenesis pathway which participated in the energy supply for the body. RPS also inhibited glycine and alanine production to block the tumor growth. This selective effect of RPS to different condition of mice would improve understanding of the antitumor pathway of RPS involved in H22 hepatocarcinoma mice.
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Probing nascent structures in peptides using natural abundance 13C NMR relaxation and reduced spectral density mapping. The main chain motional properties for a series of peptides that appear to have preferred conformations in solution have been systematically studied using solution-state nuclear magnetic resonance spectroscopy. The series of peptides were derived from the N-termini of pro-inflammatory chemokine proteins and HoxB1, a transcriptional regulator. As an unstructured control, a ten residue peptide was designed, synthesized, and found to be minimally structured from solution NMR data. The dynamic properties of the main chain for the peptides were assessed through longitudinal and transverse main chain (13)Calpha relaxation rates and the heteronuclear nuclear Overhauser effect. Motional parameters were interpreted using reduced spectral density mapping and compared with those derived from an extended Lipari-Szabo model in which the rotational correlation time was calculated for each main chain site of the peptide. Comparison of spectral density and Lipari-Szabo analyses for the peptides to those of the unstructured control peptide reveals significant differences in the dynamic behavior of the peptides. The amplitude of picosecond to nanosecond timescale motions for the main chain is observed to decrease for all of the chemokine peptides and HoxB1 over the regions that show partial structure at low temperatures. Comparatively, changes in picosecond to nanosecond timescale motions for the unstructured control peptide show no correlation with sequence position. These results indicate that there are distinguishable low temperature motional differences between an intrinsically unstructured peptide and peptides that have an inherent propensity to structure.
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Following attacks by Islamic terrorists that killed hundreds of people in Sri Lanka, BBC News expressed concern for “nervous and afraid” Muslims. BBC News’ live coverage of the aftermath of the bombings, which primarily targeted Catholic Christians, made a point of highlighting how “Sri Lankan Muslims are left nervous and afraid.” This would be as absurd as worrying about the safety of white people following the Christchurch mosque massacre. As we highlighted yesterday, instead of focusing on the perpetrators, some media outlets chose to make the issue about the reaction of the ‘far-right’. The Washington Post published a story entitled Christianity under attack? Sri Lanka church bombings stoke far-right anger in the West. Another article published by UK outlet LBC cites an analyst who worries that the Sri Lanka massacre “may lead to further violence against Muslims”. Given that nearly 800 people, many of them Catholics, have just been killed or injured by Muslim extremists, is anyone concerned about Christians? This is Paul Joseph Watson with a special message to my supporters. Big Tech wants to stop us from communicating. Don’t let them. Get the inside track and bypass the censorship by signing up for the Summit newsletter right here.
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CKPR-DT CKPR-DT is a privately owned television station serving as an affiliate of CTV in Thunder Bay, Ontario, Canada. It broadcasts a high-definition digital signal on VHF channel 2 from a transmitter in Shuniah. Owned by Dougall Media, it is sister to Global affiliate CHFD-DT and both stations share studios located on Hill and Van Norman Streets in central Thunder Bay. This station can also be seen on Shaw Cable channel 5 and in high definition on digital channel 210. On Shaw Direct, the channel is available in high definition on channel 037 (Classic) or 537 (Advanced). In June 2014, Dougall Media announced that the station would disaffiliate from CBC Television (with which it was affiliated since its 1954 sign-on) in September to become a CTV affiliate, bringing CTV back to the Thunder Bay market for the first time since sister station CHFD switched its affiliation from CTV to Global in 2010. History CKPR-DT began broadcasting on October 4, 1954 as CFPA-TV. The "PA" stood for Port Arthur, where the station was licensed until it merged with Fort William to form Thunder Bay in 1970. The station was then owned by Ralph H. Parker Ltd along with CFPA radio (AM 1230, now CKTG-FM). Three years later on July 20, 1957, Thunder Bay Electronics, owned by the Dougall family, bought CFPA-TV and changed its callsign letters to CFCJ-TV. They changed again ten years later in 1967, to CKPR-TV. In 1972, Thunder Bay Electronics launched the CTV affiliate CHFD-TV (which switched to Global in 2010) and thus CKPR-TV and CHFD-TV became one of the first private twinstick stations in Canada. In March 2010, CKPR announced it was unable to come to an agreement with CBC to continue to operate as an affiliate. CKPR filed an application with the Canadian Radio-television and Telecommunications Commission (CRTC) seeking to remove its condition of licence which mandates affiliation with CBC Television. The affiliation agreement would expire on August 31, 2011 and, according to the station would not be renewed by the CBC after that date. CKPR said that it was tentatively planning to disaffiliate as of September 1, 2010, but that it had yet to find a new programming source, and that it would be reserving the right to remain a CBC affiliate through the end of the 2010-2011 season, even if the relevant condition of licence was removed. CKPR did not disaffiliate and continued negotiations with CBC. In March 2011, CKPR announced they had come to a programming agreement, under which the station would continue to provide CBC programming in Thunder Bay, which at the time was described as having a five-year term. In early 2014, the station filed a new application to disaffiliate, indicating that it had the ability under its current agreement to opt out in September 2014. In June 2014, the CRTC approved CKPR's request to disaffiliate from CBC while suggesting to both CKPR and CBC to "consider alternate solutions" in order to "ensure the availability of the CBC's service over-the-air" in the Thunder Bay area. On September 1, 2014, CKPR-DT disaffiliated from the CBC to become an affiliate of the CTV Television Network, which returned to local terrestrial television after sister station CHFD-TV disaffiliated from that network in 2010. Despite the affiliation change, all TV service providers serving Thunder Bay, like all service providers across Canada, will continue to be required to include a CBC Television signal as part of their basic services. Shortly before the affiliation change, CBC confirmed that CBLT Toronto would be added to the basic packages of Shaw Communications cable systems in the area (channel 2 in Thunder Bay), and Tbaytel TV (channels 210 [SD] and 802 [HD]). On January 27, 2016, Dougall Media officials revealed that CKPR and CHFD are both being sustained by the payouts from life insurance policies on former owner Fraser Dougall and a former general manager who both died in 2015, and said that the stations were likely to sign off for good by September 1, barring a favourable change in CRTC policies. Both stations, however, are still in operation. Distribution CKPR-DT broadcasts on channel 2 and cable 5 in Thunder Bay, and formerly via a transmitter owned by the CBC in the Nipigon area (CBLK-TV, channel 16 with an ERP of 4.3 kW). It can also be seen on the Bell TV (channel 211) and Shaw Direct (channel 304) satellite services. The station is also available over the air and also to cable television viewers in Keweenaw County, Michigan and in parts of Cook County, Minnesota. As part of the CBC's budget cuts, the operation of CBLK-TV and the other CBC-owned analog rebroadcasters of private affiliates was discontinued on July 31, 2012. Programming As one of CTV's independently-owned affiliates, CKPR-DT currently clears the vast majority of the CTV schedule (as it did as a CBC affiliate), with a handful of preemptions in daytime and overnight for locally-sold paid programming, sometimes varying from day to day. Most notably, The Daily Show is not carried at all by CKPR in favour of infomercials, as well as the Monday edition of Dr. Phil. However, in the absence of a local noon newscast of its own, CKPR carries CTV Ottawa's lunch-hour newscast in the noon timeslot. In many cases during its CBC affiliation (as of fall 2008, up to five times per day) CBC network shows broadcast during daytime or late-night on CKPR were preempted by paid programming. For example, with the Kids' CBC block having expanded to five hours on August 31, 2009, CKPR did not air the final hour of the expanded block, just like Corus-owned CBC affiliates (at the time) in Peterborough (CHEX-DT), Oshawa (CHEX-TV-2) and Kingston (CKWS-DT), opting for an hour of paid programming instead. Also, as of February 2010, CKPR also pre-empted a half-hour of Kids' CBC at 7 a.m. for a local morning newscast (which has since been cancelled with the affiliation switch in favor of Canada AM). Furthermore, in September 2011, as more programming toward adults, CKPR began pre-empting the 9-11 am and the Saturday 11:30 am block of Kids' CBC and a few months later in 2012, CKPR also began to pre-empt the 7:30 a.m. portion of Kids' CBC for more local and paid programming. The 9-11 a.m. block of Kids' CBC eventually returned in February 2012 but CKPR continued to decline the 7:30-8 a.m., 11 a.m.-noon and the Saturday 11:30 a.m.-noon blocks of Kids' CBC. CKPR also signs off most nights after the late-night talk show Conan on Monday to Thursday and the late network movie on weekends. When CHFD was primarily a CTV affiliate, Global programs that could not be cleared by CHFD-DT, such as Survivor, would occasionally air on CKPR-DT instead. In the past, some CTV programming not cleared by CHFD may have also aired on CKPR. Digital television and high definition CKPR-DT flash cut to digital in early August 2011 alongside sister station CHFD. Through the use of PSIP, digital television receivers will display CKPR-DT's virtual channel as 2.1. In January 2011, Dougall Media applied with the CRTC to broadcast its digital signal instead on channel 2, following the digital conversion date. See also CKPR-FM CHFD-DT References External links KPR-DT Category:Media in Thunder Bay Category:Television channels and stations established in 1954 KPR-DT Category:1954 establishments in Ontario
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Q: Every time I close tab in IE, Windows displays 'Internet Explorer has Stopped Working' Every time I close tab in IE, Windows displays 'Internet Explorer has Stopped Working' _ Dugh.... How to fix it? Additional information: IE: 8.0 OS: Windows 2008 x32 in Desktop mode It started happening after I moved computer to different domain Problem resolution displays: data execution prevention I turned off DEP for Internet Explorer - it didn't help. A: Standard troubleshooting: Go into Control Panel, and choose "Internet Options". Switch to the Advanced tab. Click the Reset Internet Explorer Settings button. Click Reset to confirm the operation. Click Close when the resetting process finished. Uncheck Enable third-party browser extensions. Click Apply, click OK. If the situation has improved, try returning third-party browser extensions.
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**3 - 4*u**2 + 2*u - 3. Suppose -5*g = -4*d + 41, 2*d = 4*d - g - 13. Let w be b(d). Solve w*j + 8 = -h, -2*h = 3*j - h + 6 for j. -1 Suppose v + 73 = 5*u - 0*v, 40 = 2*u - 4*v. Solve 5*s + 9 = -b - 10, -3*s - u = -2*b for b. 1 Suppose 0 = -4*m + 31 - 7. Solve 2*g + 2*r = 6, -m*r = -5*g - 2*r + 6 for g. 2 Let x(m) = 2*m**2 + 2*m + 2. Let k be x(-2). Suppose 5*l - 7*y = -2*y - 5, 6 = -4*l + 5*y. Suppose -t = -2 - l. Solve 2*f + 12 = i, -i + t*f + 10 = -k for i. 4 Let z be (-10)/(-35) + 26/7. Let b(i) = -4*i + 7 + 3*i - 2. Let o be b(z). Solve -5*u + 3*n + 10 = 0, 2*n = 2*u + o - 5 for u. 2 Let k = 3 - 2. Suppose 13 = 2*c + k. Let g = c - 1. Solve 3*d + 15 = 5*y, -g + 0 = d + 5*y for d. -5 Suppose 3 = c - 7. Let v be 8/20 + (-4)/c. Solve 15 = 3*p, v*u + 4*u + 1 = p for u. 1 Let v(o) = 4*o**3 - 2*o**2 + 1. Let u be v(1). Let c be (1/2)/(u/12). Let t be c/(-6) - 146/(-6). Solve -4*r - 3 = -3*m + t, 2*r + m + 1 = 0 for r. -3 Let y = 4 + -4. Suppose 4*f - 6 = 2*f. Let t be ((-3 - f)/1)/(-2). Solve -16 = 3*i - o, y*o - t*o = -5*i - 32 for i. -4 Suppose 3*m = -0*m - 3. Let w be (-1 + m)*(-10 - -9). Suppose -x - w*i - 3 = 0, 0*x = x - 3*i - 17. Solve 0*j + 2*h - x = j, 2*h = -5*j + 23 for j. 3 Let y = 128 + -65. Suppose -4*t = -t - y. Let v(l) = -l**2 - 34*l + 114. Let z be v(-37). Solve -2*n - t = -3*c, 9 = -0*n - z*n for c. 5 Let k(l) = -4*l**3 + l. Let t be k(-1). Solve -o + 3*o - 5*j - 11 = 0, -4*j = -t*o + 6 for o. -2 Let m(g) = 8*g**2 + 2*g + 4. Let b be m(-3). Let o be b/4 - (-1)/2. Let t = -13 + o. Solve 30 = -t*f + 5*q, -3*f + 0*f + 5*q - 28 = 0 for f. -1 Let q = 2 + -3. Let y(p) be the third derivative of 11*p**5/60 + p**4/24 + p**3/6 - 2*p**2. Let n be y(q). Solve 2*d + 8 = 4*r - 18, -n = 2*d - r for d. -3 Let f(h) = -h**2 - 4*h + 1. Let x be f(-4). Solve 3*u = 4*b - 10, 4*b + 2*u - x = 19 for b. 4 Let b be 13/(-1*(-1 - 0)). Let p = b + -7. Solve -3 + 11 = 4*g + 4*a, 3*g - a - p = 0 for g. 2 Suppose y + 10 = 2*y. Let l(c) = -c**3 + 5*c**2 + 3*c + 12. Let o be l(6). Let x = o + y. Solve -5*j + 16 = -x*b, -4*j + 11 = -2*b - 3*b for j. 4 Let g(l) = l**2 + l - 1. Let s(o) = -6*o**2 - 5*o + 6. Let q(u) = -4*g(u) - s(u). Let k be q(2). Solve -6*y = -i - 4*y - k, -2*i - 6 = -2*y for i. 2 Let g(x) = -x**2 + 10*x + 9. Let t(c) = 2*c**2 - 11*c - 10. Let f(d) = -3*g(d) - 2*t(d). Let s be f(-6). Solve 0 = 4*w + 5*j - s, 3*w - 9 = j - 3*j for w. 5 Let t = 5 + -2. Let x(w) = -w**2 + 10*w - 7. Let g be x(9). Suppose -6 + 0 = -g*v. Solve 2*z = 4*p + 16, -4*z - v = t*p + 9 for p. -4 Suppose -2*g + 18 = -2*u + 2, -4*g + 5*u = -35. Solve 5*c = -g*y, 18 = -4*c - 2*y + 7*y for c. -2 Let s(t) = -7 - 2 + 10*t - 8*t. Let v be s(8). Let x be (-2)/(-1) - (5 - v). Solve -x*d - 4 = 0, 5*q + 0 = 5*d - 5 for q. -2 Let i be 5 + -2 - 21/7. Solve i = 4*w + 4*f, 5*w + 3*f + 3 + 3 = 0 for w. -3 Let k be 3*1 - (6 + -5). Suppose 2 - 34 = -3*p - 4*w, -3*p - k*w + 22 = 0. Solve 5*g + 3*x + p = 7*x, -2*g + 3*x = -4 for g. -4 Let k be ((-28)/(-5))/((-24)/420). Let s be (-378)/k - (-1)/7. Solve f = 2, 0 = -s*p - f + 6*f - 14 for p. -1 Let u(n) = 3*n - 10. Let h be u(4). Solve -h*l = -3*v - 3*l - 14, 4*v - 3*l = -10 for v. -4 Let m be (-4)/10 + (-54)/(-10). Suppose 2*t - 3*o = -0*t + 6, 4*t + m*o + 10 = 0. Let n be (6/(-9))/((-2)/36). Solve -5*q = 2*s - n, -2*s - 3*q + t = -4 for s. -4 Suppose 139 = -2*n - 61. Let x = n + 60. Let k = x + 68. Solve 0 = -5*p - 3*g - k, 4*p - 5*p + 5*g = 0 for p. -5 Let v be 3/5 - 117/(-5). Let o = v - 10. Let c be 4/o + (-78)/(-21). Solve -4*n - 2 - 6 = 5*h, -c*h + 2*n + 4 = 0 for h. 0 Suppose 0 = 2*r - 3*o, o + o + 11 = 5*r. Suppose 0 = -2*a - z - r + 5, 5*a - 8 = -z. Solve -14 = -a*u + 5*x, 0 = -4*u - 3*x + 4*x + 10 for u. 2 Let f(k) = -k + 3. Let q be f(0). Solve 5*x - 40 = -0*x - 3*y, q*y = x + 10 for x. 5 Suppose -2*d + 0 = -30. Solve 0 = -c - 2*y + 3*y + 5, 5*c = -5*y + d for c. 4 Let q(p) = 4*p + 4. Let n be q(6). Let j(s) = -s**2 + 2*s + 2. Let w be j(4). Let k be n/6 - (-4)/w. Solve -f - k*f - m = -5, m - 5 = 0 for f. 0 Let x = -60 - -62. Solve -4*i + 10 = -z, x*i - 2 = -i - 2*z for i. 2 Suppose -4*h - h + 45 = 0. Let i = h + -5. Suppose -x + i*x = 15. Solve 3*v = -d - 12, -v + 4*v = x*d + 6 for d. -3 Let v = -6 + 9. Let r(c) = c**2 - 4*c + 6. Let w be r(5). Suppose -7*f + 5*h + 17 = -v*f, 5*h + w = 2*f. Solve -8*o = -4*j - f*o + 31, -2*o = -2*j + 14 for j. 4 Let f be (-4)/(-2)*(-3)/(-2). Let r be ((-3)/2)/(2/(-4)). Let s be r/(-4)*(-7 - -3). Solve 12 = -4*y, -f*y - 15 = s*v - y for v. -3 Suppose -2*f - 3*f = 55. Let d = 11 + f. Solve 3*t = -5*o - d*o - 22, -15 = 5*t + 4*o for t. 1 Suppose 0 = 3*d + 2*d. Suppose -g + 3*g - 8 = d. Suppose 5*c = -3*k + 10, -g*k = -9*k + c + 26. Solve -6 = -5*m + 5*v + 4, 40 = -5*m - k*v for m. -3 Suppose r = 2*r - s - 2, 0 = -2*r + s + 3. Suppose -5*x = -2*a - 2, 3*a + r + 2 = -2*x. Solve -6 = 4*k + 2*m, x*k + 4*k - 4*m + 24 = 0 for k. -3 Suppose m = -y + 6, -5*y + y + 5*m - 12 = 0. Suppose 0 = 2*n - 0*n - y. Suppose 0 = -t + 4, 2*t = 3*a - 0*a - n. Solve -4*d - 12 = 2*j, -1 = -d - a*j + 1 for d. -4 Let o = -1 - -1. Let s = -2 - -7. Suppose -30 = -8*f + 2*f. Solve -f = -s*z - a, -3*z + 2*a = -o*z + 10 for z. 0 Let w = -9 - -12. Solve -5*m - 15 = -3*o, 5 = -w*m + m + o for m. 0 Suppose b + 2*b = 69. Suppose 4*k - i - 14 = -2*i, -5*k + 2*i + 24 = 0. Solve 2 + b = -d + k*c, 30 = -5*d + c for d. -5 Let o(f) = f**2 + 2*f + 3. Suppose 6 = 5*d - 8*d. Let q be o(d). Suppose 5*i - 9 - 11 = 0. Solve p = -i*l - 4, -2*l - 10 = q*p + 2 for l. 0 Suppose 2*m + 18 = 4*i - 0, i = 5. Let z(h) = -h**2 + h. Let t be z(m). Let x = t + 0. Solve -4*s = -3*r - 3, -4 = 3*s - x*r - r for s. -3 Let h be 0/(-3) - (3 - 0). Let f = 8 + h. Suppose o + s + 5 = 4*o, 6 = f*o - 4*s. Solve 2*g + 16 = -4*a, -g - 4*g = -o*a + 4 for g. -2 Let n = 14 - 20. Let q be (-16)/n - (-36)/(-54). Solve 4*p + q*z = -18, 0 = -3*p + 2*z + z - 9 for p. -4 Let w = -46 + 46. Solve -q + 1 = -4*k - 21, w = 2*q + 3*k + 11 for q. 2 Suppose -56 = -26*u + 22*u. Solve 3*m + 18 = -3*k, 5*k - 4*k + 5*m = -u for k. -4 Suppose 2*k - 3 = k. Suppose o - 4 = 4*i, 0*i = -k*i - 3*o + 12. Solve i = 2*x + x + 2*w + 2, 2*x - 5*w = 5 for x. 0 Suppose -5*h = 4*o - 13, h = 4*o - 9 + 26. Solve -h*m + 26 = l + l, -l - 9 = -3*m for m. 4 Let m(r) = -r**2 - 9*r + 1. Let g be m(-8). Let q = g - 2. Let z = -9 - -14. Solve -4*k - 4 + q = -3*b, -3*k = z*b - 24 for k. 3 Let f(c) = -4*c**3 + 2*c + 1. Let y be f(-1). Let h be 8/y*(-6)/(-4). Solve -v = -2*o + 3, 0 = -v - h*o + 28 - 7 for v. 5 Suppose 0 = -0*v + 5*v + 35. Let j be v/(-3) + (-2)/6. Solve -h - 2*u + 19 = j*h, 4*h - 2*u - 16 = 0 for h. 5 Let p be -1 - 5/((-5)/6). Let o be ((-3)/(-2))/((-1)/2). Let j(v) = -v**3 + 2*v - 4. Let a be j(o). Solve -5*w = -20, p*t + a = -4*w + 58 for t. 5 Suppose 0 = -3*z + 17 - 2. Suppose -z*v + 10 + 20 = 0. Let t be (-2 + 0)*v/(-4). Solve 0 = 5*g - 4*k - 20, g + t*k - 3 = 1 for g. 4 Let a = -15 + 25. Suppose 0*l + 172 = 5*l - 3*f, 5*f + 135 = 4*l. Solve -4*o - l = 3*q, 4*q - 2*o + a = -0*o for q. -5 Let t be 3*(-2)/((-18)/15). Solve -o + 2*p = 7*p + 10, -5*o = t*p + 30 for o. -5 Let i(d) = -d**3 + d**2 + d + 7. Let c be i(0). Suppose 0 = z - 3 + 1. Let q be 2*z/(-4)*-2. Solve 3*y = -12, c*y - q*y + 36 = 4*u for u. 4 Let a be ((-266)/(-18) - (-4)/18) + 4. Solve -2 = -3*s + 4*l - 3, -5*s - 2*l - a = 0 for s. -3 Suppose -l + 8 = l. Suppose 23*q = 10*q. Solve q = 3*u - 5*h + 4 - 6, 9 = -5*u - l*h for u. -1 Let h be (4/10)/(2/10). Suppose h*g + 2*g = 2*z + 4, -5*g = -z - 8. Suppose 3*p = -2*k - 3*k + 22, -g*p = 5*k - 23. Solve k = 5*x + 4*w, 4*w = -2*x - 2*x for x. 5 Let j = 18 + -12. Suppose -l - 10 = -j*l. Suppose 0*b + 12 = 3*b. Solve b*g + l*m - 5 = -3, g = -m - 1 for g. 2 Let q = 7 + -10. Let o be ((3 + q)/(-3))/(-2). Suppose o = 2*n + 4*k, 4*n + 3*k - 4 - 6 = 0. Solve -s = -5*p + 3*s + 11, -5*p - n*s = 21 for p. -1 Let w be (6 - -6)*(-3)/(-9). Solve h + 10 = w*n, -h + 3*h - 4*n + 12 = 0 for h. -2 Suppose 4*a = -b - 4*b + 17, -3*a = 6. Let h = -5 + b. Suppose 2*v - 14 = -2*y - h, -3*y + 17 = v. Solve -17 = 5*p + v*k, 5*p - 4*k + 2 = -9 for p. -3 Suppose -3 - 1 = -x, 26 = 2*s + 4*x. Suppose 7 = 4*z + h, s*h - 3*h + 22 = 4*z. Solve 0*y - 3*y = 5*g - 12, -z*g + 11 = -2*y for y. -1 Let o(m) = -m - 4. Let h b
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111
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1.0 Field of the Invention The invention relates to compositions and methods for the cryopreservation of cellular vaccines. More specifically, the invention relates to the use of particular compositions comprising cryoprotective media that includes hydroxyethyl starch (HES) and glycerol or DMSO together with recombinant live cancer cells. The compositions can be frozen and thawed, when desired, for use as a cellular vaccine for the treatment of cancer. 2.0 Background of the Invention At certain periods of time in a tumor's cell growth, the patient's immune system has the ability to recognize the growth as abnormal (or non-self). As a result, various methods have been developed which take advantage of the patient's own immune system to fight cancer. Exemplary methods include the use of polyclonal and monoclonal antibodies, non-specific immune system stimulants, such as cytokines, protein or peptide subunit vaccines (e.g., using antigens that are often associated with cancer cells, such as tumor-specific antigens and tumor-associated antigens), adoptive immunotherapy or cellular therapy, gene therapy, cellular vaccines, etc. See, e.g., WO 00/33871. Cellular vaccines wherein cells (or derivatives thereof) are the therapeutic agent are currently in clinical testing for treatment of cancer. Such cellular vaccines provide advantages over isolated protein vaccines in that whole cells are the vehicle for a broad range of antigens, e.g., on the cell surface. See, for example, Dranoff et al. WO 93/06867, Gansbacher et al., WO 94/18995, Jaffee et al. WO 97/24132, Mitchell et al. WO 90/03183 and Morton et al. WO 91/06866, each of which is expressly incorporated by reference herein. Cells for use in such cellular vaccines can be modified, e.g., to express a protein which modulates the immune response to the cell. For example, a gene encoding a cytokine or costimulatory molecule may be introduced into cells derived from, e.g., a primary tumor taken from a patient, to create recombinant cancer cells. When the cytokine or costimulatory molecule is expressed, it is capable of modulating the immune response to the cell. The recombinant cancer cells may be expanded in vitro, treated to prevent further growth and returned to the patient. Appropriate timing of administration(s) and good cell viability are required for effective treatment with a cellular vaccine. Thus, it is important to be able to store recombinant cancer cells for use at selected time points, appropriate to particular treatments. Storage and maintenance of viability are important in order to allow for transportation, to decrease the amount of cell divisions the cells undergo before use in treatment and to ensure that an adequate and reproducible dose is delivered to the patient. Freezing of cell compositions with maintenance of viability has been the subject of considerable research. Maintenance of cell viability following freezing and thawing continues to be a challenge. In the freezing process as the liquid component of a cell is changed to a solid, ice crystals are formed and damage can occur to the cells. At least two types of damage to cells is possible when ice crystals are formed. Rapid growth of ice crystals may physically disrupt membranes and subcellular organelles and may even lyse cells. Slow growth of ice crystals may result in cellular dehydration (because of the exclusion of electrolytes from the ice crystals) and extra-cellular ice formation. See, e.g., Gorlin, (1996) Journal of Infusional Chemotherapy, 6(1):23–27. In an attempt to minimize the effects of ice crystal formation, cells are typically frozen in medium with cryoprotectants. Cryoprotectants protect the cells during freezing in a variety of ways. Collagiative cryoprotectants penetrate the cell and decrease the osmotic gradient across membranes. Vitrifying cryoprotectants increase the glass formation of the solution thereby creating a glass wall around the cell, which prevents dehydration. Cryoprotectants can also work by inhibiting ice crystal formation. See, e.g., Gorlin, (1996) Journal of Infusional Chemotherapy, 6(1):23–27. Different cell types vary in their permeability to water and in their sensitivity to solute concentration. Leibo et al., (1970) Cryobiology, 6(4): 315–332. As a result, different types and combinations of cryoprotectants have been found to be effective to preserve specific types of cells. For example, human bone marrow committed stem cells have been shown to be preserve by a cryoprotectant combination of dextran, glycerol, and dimethyl sulfoxide (Odavic et al. (1980) Experienta 36:1122–1124), and mouse marrow stem cells have been shown to be preserved by polyvinylpyrolidone (PVP), sucrose or glycerol. See, e.g., Stiff et al. (1987) Blood, 70(4): 974–978; Venkataraman, (1997) Cryobiology, 34:276–283; Wang et al., (1998) Cryobiology, 37:22–29; Merten et al., (1995) Biologicals, 23:185–189; and, Yoshida and Takeuchi, (1991) Cytotechnology 5:99–106. Polymers, such as hydroxyethyl starch (HES), have been used to cryoprotect human monocytes and unfractionated cells for use in bone marrow transplantation. See, e.g., Takashi et al., (1988) Biophysical Journal, 54:509–518; and Stiff et al. (1987) Blood, 70(4): 974–978. Cryoprotective media for cellular vaccines has not been reported. Thus, there remains a need for cryoprotective media and procedures that can be used to successfully preserve cellular vaccines for use as therapeutic agents. In view of the above, materials and methods that would provide for successful preservation and recovery of cells with a high percentage viability following freezing and thawing would be highly desirable for use in cellular vaccines. The present invention addresses this need, as will be apparent from the detailed description provided herein.
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NGC 4631 NGC 4631 (also known as the Whale Galaxy or Caldwell 32) is a barred spiral galaxy in the constellation Canes Venatici. This galaxy's slightly distorted wedge shape gives it the appearance of a herring or a whale, hence its nickname. Because this nearby galaxy is seen edge-on from Earth, professional astronomers observe this galaxy to better understand the gas and stars located outside the plane of the galaxy. Starburst and superwind NGC 4631 contains a central starburst, which is a region of intense star formation. The strong star formation is evident in the emission from ionized hydrogen and interstellar dust heated by the stars formed in the starburst. The most massive stars that form in star formation regions only burn hydrogen gas through fusion for a short period of time, after which they explode as supernovae. So many supernovae have exploded in the center of NGC 4631 that they are blowing gas out of the plane of the galaxy. This superwind can be seen in X-rays and in spectral line emission. The gas from this superwind has produced a giant, diffuse corona of hot, X-ray emitting gas around the whole galaxy. Nearby galaxies and galaxy group NGC 4631 has a nearby companion dwarf elliptical galaxy, NGC 4627. NGC 4627 and NGC 4631 together were listed in the Atlas of Peculiar Galaxies as an example of a "double galaxy" or a galaxy pair. NGC 4631 and NGC 4627 are part of the NGC 4631 Group, a group of galaxies that also includes the interacting galaxies NGC 4656 and NGC 4657. However, exact group identification is problematic because this galaxy and others lie in a part of the sky that is relatively crowded. Estimates of the number of galaxies in this group range from 5 to 27, and all studies identify very different member galaxies for this group. See also NGC 891, a similar edge-on spiral galaxy NGC 4565, a similar edge-on spiral galaxy NGC 5907, a similar edge-on spiral galaxy References External links APOD (2004-01-23) – The Whale Galaxy APOD (2010-05-17) – The Whale Galaxy (a better image) Category:Barred spiral galaxies Category:NGC 4631 Group Category:Canes Venatici 4631 07865 42637 281 032b
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Dunbar Tank The perfect sweater tank. The Dunbar is a knit tank with a stripe pattern, higher neckline and an easy fit. Pair the Dunbar with the Caesar Pants or your favourite denim shorts for the perfect summer look.
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DFT, QTAIM, and NBO investigations of the ability of the Fe or Ni doped CNT to absorb and sense CO and NO. The structures and intramolecular interactions of complexes (FeCNT-CO, FeCNT-NO, NiCNT-CO, and NiCNT-NO) formed by the Fe or Ni doped single-wall carbon nanotube (FeCNT or NiCNT) and gas CO or NO were studied using density functional theory, quantum theory of atom in molecule (QTAIM), and natural bond orbital methods. The adsorption processes of CO and NO on surfaces of FeCNT and NiCNT are chemisorption, energetically favored, exothermic, and spontaneous. High temperature is not good for adsorption. Introducing NO more obviously elongates the distances between Fe/Ni and C atoms and decreases ∠CFe(Ni)C than adding CO. QTAIM analysis shows that the covalent bonding interactions of FeCNT-NO (NiCNT-NO) are stronger than that of FeCNT-CO (NiCNT-CO). NO plays a role of electron acceptor while CO is electron donator in complexes. Electrostatic interaction of FeCNT-NO (NiCNT-NO) is stronger than that of FeCNT-CO (NiCNT-CO). The stronger intramolecular interactions of FeCNT-NO and NiCNT-NO reveal that FeCNT and NiCNT are more effective to adsorb and sense NO than CO. CO and NO considerably change the electronic properties of FeCNT and NiCNT, which is useful for designing sensors for CO and NO.
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1. Field of the Invention The present invention relates in general to the field of catheters for use in exploratory procedures, diagnosis and treatment of biologic conditions, and more particularly, to a catheter meter for determining spacial quantities such as linear distance in a vessel or other comparable environment. 2. Related Art Catheters are well known in the art and are commonly introduced or inserted into canals, vessels, passageways or body cavities to inspect a region of interest or inject or withdraw fluids from the region or to treat the region, such as to keep a restricted passage open. One medical procedure is known as angioplasty, which has become widely accepted as a safe and effective method for treating various types of vascular diseases. For example, angioplasty has been used for opening stenoses throughout the vascular system, and particularly for opening stenoses in coronary arteries. One common form of angioplasty is called percutaneous transluminal coronary angioplasty. This procedure uses a dilation catheter having an inflatable balloon at is distal end. Using a fluoroscope and radiopaque dyes for visualization, the distal end of the dilation catheter is guided into position across the stenosis and the balloon is inflated for a brief period to reopen the artery and reestablish adequate blood flow. A number of balloon catheter designs have been developed and have contributed to the safety and acceptability of percutaneous transluminal coronary angioplasty and similar medical procedures. The most common design is known as an "over the wire" balloon catheter. This prior art device typically uses a relatively large lumen for passing a guide wire and injecting angiographic visualization dye to assist in placing the device. A second parallel lumen is provided for inflation and deflation of the balloon. Typically, a steerable guide wire is positioned within the larger lumen and the entire assembly is maneuvered into an initial position within the target artery through a previously positioned large diameter guide catheter. Once near the sight of the stenosis, the guide wire can be rotated and axially extended or retracted into position across the lesion. The catheter is then advanced along the guide wire to position its balloon end across the lesion prior to inflation of the balloon and dilation of the stenosis. Typically, the vascular stenosis is located and the dilation balloon positioned by fluoroscopy. In that procedure, the radiopaque dyes are injected into the vessel after the catheter has been introduced into the vessel. The stenosis is then located and the end of the catheter is determined relative to the stenosis. The inflatable balloon can then be moved across the stenosis and inflated to open the stenosis. While fluoroscopy is a well accepted procedure and can be properly carried out by an experienced physician, it nonetheless requires injection of the radiopaque dyes and use of x-rays to be able to view the remote area of interest. Once the stenosis is located, dilating the stenotic lesion requires a substantial effort, which is not always entirely successful. For example, successful treatment requires a properly sized inflation balloon to be placed across the stenosis and inflated to remove the stenosis. Determining the proper balloon size is often difficult and not always correct on the first try, requiring a second procedure with a different sized balloon. In one procedure for estimating the size of the stenotic lesion, sufficient radiopaque dye must be kept in the vessel to permit viewing by fluoroscope. In order to obtain sufficient information about the stenotic lesion to estimate its size, the patient must be turned through various positions to obtain a series of different views of the vessel. If the patient remains sufficiently immobile, sufficient views of the vessel taken, even though the vessel such as a cardiac artery may be moving, and the radiopaque dye is maintained in the vessel, it is nonetheless difficult to accurately estimate the size and form of the stenotic lesion. If the inflatable balloon chosen to open the stenotic lesion is too small, the stenosis will not be sufficiently opened, and a larger balloon must be used after the first procedure. If the inflatable balloon is too larger, the vessel may reflexively reconstrict, limiting adequate blood flow through the vessel. Repeated processes result in trauma to the patient and possible harm to the vessel receiving the catheter, thereby increasing the risk of complications. Therefore, it is not only difficult to accurately measure linear distances using catheters but it is also difficult to adequately measure other quantifiable parameter such as size and shape. This inability to adequately measure and quantify unknown quantities and the possibility of repeated procedures may ultimately lead to complications during certain medical procedures. In the past these duel lumen catheters, however, have been relatively bulky and stiff, making their use difficult for any lesions except those proximal and localized in non-tortuous, easily accessible vessels. Accordingly, it is an object of the present invention to provide a catheter depth gauge which can measure linear distance from the top or proximal of the catheter device to an object of interest at the distal end. It is an additional object of the present invention to provide a device which will allow a physician to quantify distances and other spacial parameters in order to provide a reference point for surgery, data for diagnosis and treatment of symptoms and to minimize the number of procedures and steps necessary to achieve the desired result. It is a further object of the present invention to provide a device which allows a physician to determine the size and extent of conditions such as vascular stenosis for purposes of diagnosis and treatment of vascular disease. It is an additional object of the present invention to provide a device which allows a physician to determine which vascular areas of a particular vessel should be treated and which areas may be passed over. These and other objects are achieved by the device of the present invention.
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Q: CSS3 Box Shadow Direction I'm a total CSS3 noob, so please bear with me. I have the following HTML: <input name="firstName" id="firstName" type="text"><span class="tip">Just a tip</span> ... with the following CSS applied to the "input" field and "span" tag: input[type="text"], input[type="password"], textarea { border-top:1px solid #5F5F5F; border-left:1px solid #5F5F5F; border-bottom:1px solid #5F5F5F; border-right:1px solid #5F5F5F; border-top-left-radius:5px; border-bottom-left-radius:5px; padding:10px; width:200px; } input[type="text"]:hover, input[type="password"]:hover, textarea:hover { border: 1px solid #22C3EB; -webkit-box-shadow: 0 0 5px #22C3EB; -moz-box-shadow: 0 0 5px #22C3EB; box-shadow: 0 0 5px #22C3EB; } input[type="text"]:focus, input[type="password"]:focus, textarea:focus { border: 1px solid #972324; -webkit-box-shadow: 0 0 5px #972324; -moz-box-shadow: 0 0 5px #972324; box-shadow: 0 0 5px #972324; } .tip { font-size:11px; border-top:1px solid #22C3EB; border-right:1px solid #22C3EB; border-bottom:1px solid #22C3EB; border-left:1px solid #5F5F5F; border-bottom-right-radius:5px; border-top-right-radius:5px; padding:12px 10px 10px 10px; width:200px; } .tip:hover { border: 1px solid #22C3EB; -webkit-box-shadow: 0 0 5px #22C3EB; -moz-box-shadow: 0 0 5px #22C3EB; box-shadow: 0 0 5px #22C3EB; } Basically, it is a rounded text field, with another span tag on the right, which also has rounded outer edges. It looks similar to the Twitter sign-up page. If you click on each input field field, you will get a general idea of the way my input and span tags are styled. Is there a way to prevent the "box-shadow" from casting a shadow between the "input" and "span" fields? So, no shadow on the right side of the "input" field, and no shadow on the left side of the "span" tag? Please note I am trying to support both Mozilla and Webkit rendering engines in this CSS. Thank you for your time, spryno724 A: use inner-wrap and use box-shadow: -5px 0 0px #FFFFFF; http://jsfiddle.net/pramendra/y67Yt/3/
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Problem: An estimated 31,000 new HIV diagnoses occur each year among men who have sex with men (MSM), representing more than half (56%) of all new HIV infections in the U.S., and MSM are the only group with an increasing incidence of new HIV infections. Additionally, receiving an HIV diagnosis is a traumatic event for many-Over 40% of people living with HIV have posttraumatic stress disorder and as many as 40% these individuals report being diagnosed with HIV as their index trauma. Finally, the first year following an HIV diagnosis is a critical period for prevention as over 50% of newly diagnosed MSM report HIV transmission risk behavior within 3 to 12 months of diagnosis. Despite these statistics, and CDC's efforts to promote HIV prevention among people living with HIV, few "positive prevention" interventions exist, particularly for MSM. Aims: The proposed research will develop and pilot test an integrated risk reduction intervention for reducing traumatic stress and sexual HIV transmission risk behavior among newly HIV diagnosed men suitable for implementation in the medical care setting by staff commonly available in such settings. The intervention will (1) address the acute stress of receiving an HIV diagnosis to maximize men's ability to attend to risk reduction and health promotion messages and adapt to a new diagnosis;(2) integrate risk reduction into multidisciplinary care;(3) assist newly diagnosed men in the transition into medical care;and (4) take advantage of the teachable moment presented by the HIV diagnosis to change sexual risk behavior. Methods: Eighty newly HIV diagnosed men (within the previous three months) will be randomly assigned to either: (1) the trauma-focused risk reduction intervention experimental condition, or (2) a usual care comparison condition. Following intervention completion, study providers and participants will be interviewed and logistics evaluated to determine the feasibility and acceptability of the intervention. The following hypotheses will be tested to establish preliminary evaluations of efficacy: (1) Traumatic stress and sexual HIV transmission risk behavior will be reduced across the nine-month study period in the risk reduction intervention condition in relation to the usual care comparison condition, and (2) Depressive symptoms will be reduced and utilization of medical and social services will be increased among newly diagnosed men in the risk reduction intervention condition in relation to the usual care comparison condition. Significance: Positive prevention delivered in the "teachable moment" following an HIV+ diagnosis and seamlessly integrated within medical care will take advantage of a singular window of opportunity to reduce emotional distress and risk behavior, routinize prevention in the care setting, and establish a trajectory of safer sexual behavior for newly diagnosed men. If successful, this research will provide an HIV positive prevention intervention model that can be translated into a sustainable model of care for newly diagnosed MSM, which will meet an urgent need for care programs that identify, treat, and prevent HIV infections. PUBLIC HEALTH RELEVANCE: An estimated 31,000 new HIV diagnoses occur each year among men who have sex with men (MSM), representing more than half (56%) of all new HIV infections in the U.S., and MSM are the only group with an increasing incidence of new HIV infections. The first year following an HIV diagnosis is a critical period for prevention as over 50% of newly diagnosed MSM report HIV transmission risk behavior within 3 to 12 months of diagnosis. The proposed research will develop and pilot test an integrated, care-based risk reduction intervention to address the acute stress of receiving an HIV diagnosis to maximize newly diagnosed men's ability to attend to risk reduction and health promotion messages and adapt to a new diagnosis.
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This brilliant video shows just how much Mohamed Salah's penalty for Egypt on Sunday meant to some people - and, hopefully, he will have Liverpool fans doing the same thing next weekend when his side take on Manchester United. The 25-year-old was the hero of the hour for Egypt they beat Congo 2-1 to secure their place in the World Cup for the first time since 1990. And it was the Liverpool forward who opened the scoring midway through the second half with a neat, close-range finish at the Borg El Arab Stadium. However, Congo levelled with just three minutes of normal time remaining when Arnold Bouka volleyed home. This had dampened spirits in Alexandria but Salah held his nerve after Egypt were awarded a spot kick deep into stoppage-time.
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There are different types of HIIT but an easy one to begin with is to simply warm up for 3 minutes on an elliptical machine or by walking. Then work out for 30 seconds so that at the end of the exercise you feel satisfied. Reduce the speed to slow down to a moderate pace. Do this 7 more times or for total 8 intervals. Start with one interval and as your body is ready to take more increase the intervals. Studies show that HIIT to be the absolute premier cardio for weight loss and optimal health as compared to longer, traditional cardio. It’s stunning how often we eat out of boredom, nervousness, habit, or frustration—so often, in fact, that many of us have actually forgotten what physical hunger feels like. If you’re hankering for a specific food, it’s probably a craving, not hunger. If you’d eat anything you could get your hands on, chances are you’re truly hungry. Learn how to recognize these feelings mistaken for hunger, then find ways other than eating to express love, tame stress, and relieve boredom. But talk to your doctor if you think you’re always hungry for a medical reason. Here are 10 medical reasons you might be hungry. You can blame biology for your sweet tooth. We’re hardwired to have a preference for sweets, and this drive is universal and begins early on, according to research on the subject. Sugar makes food taste good, so food companies add it to everything from breads to soups to salad dressings to cereals, yogurts and more. This adds up to way too much sugar! Whole foods include fruits, vegetables, beans, nuts, seeds, whole grains, eggs, seafood, chicken and so on. Food philosophies may differ around which of these foods to emphasize, but that’s okay, since the evidence shows that there isn’t a single best way to lose weight. The goal is to select an approach that feels sustainable to you. If you can easily live without pasta, perhaps a low-carb method centered around veggies and quality proteins, like seafood, chicken, and lean beef would be a good fit. Vegans and vegetarians can lose weight by choosing fruits, vegetables, whole grains and plant proteins. Nut lovers may do well shedding pounds with a Mediterranean-style menu. Whatever diet appeals to your appetite and way of life, focusing on whole foods is something that all plans promote. The secret to a slimmer stomach in no time? A whole lot of fiber in your diet. Although many people are loath to add carbs to their diet when they’re trying to lose weight, adding the right, fiber-rich ones can have inches off your belly in a hurry. In fact, researchers at Wake Forest Baptist Medical Center found that every 10-gram daily increase in soluble fiber was associated with a 3.7 percent decrease in dangerous visceral fat over five years. Those who were active got even leaner, shaving off twice that much fat in the same amount of time. To start ditching that extra belly fat today, add the 30 Best Foods For Fiber to your menu! Drink at least 2 liters (0.53 US gal) of water each day. Water has the double effect of both hydrating your body and filling your stomach with a certain volume of a liquid that has zero calories. The Institute of Medicine determined that an adequate intake (AI) for men is roughly 3 liters (0.8 US gal) (about 13 cups) of total beverages a day. The AI for women is 2.2 liters (about 9 cups) of total beverages a day.[12] Want to lose that belly fat fast? In your dreams! Seriously, though: a good night’s sleep is one of the best ways to get rid of that extra fat around your waist for good. Among the 60,000 women participating in the Nurses’ Health Study, those who snoozed for fewer than five hours a night were at the greatest risk of becoming obese and gaining 30 or more pounds over the course of the 16-year study period when compared to those who slept for seven or more hours. There are so many products designed to help you drop a few pounds. Keto Shred Pills are just one of the many. We’ve looked at a lot of these products, and we will tell you: from what we’ve seen of Keto Shred Supplement, we like it, but it doesn’t beat out our favorite. So, we’ll tell you what we’ve learned, but we would really recommend that you look at our favorite one as well! We think you’ll like it. We’ve linked it in the image below this paragraph, so it’s easy to get to. Now, back to Keto Shred XR. 5. Stand up. Researchers at the Mayo Clinic found that lean people spend two more hours per day on their feet than overweight people. Participants in the study who stood, paced, and fidgeted burned as many as 350 extra calories a day and were much leaner than those who didn’t move as much. Get up from your desk at work, talk on the phone while standing, and stay on your feet in waiting rooms—the simplest effort will yield an extra calorie burn that may help you shed those remaining pounds. 2. Decline Bench Sit Up Ceiling Touches: This great exercise works on your shoulder, abs and lower back. Sit on the bench with the weight on your lap. As you move backwards, lock your arms and raise the weight above your body. Touch your back to the bench and use your abs to sit up. As you sit up you should keep your arms and weight pointed to the ceiling. Weight loss ultimately comes back to the concept of calories in, calories out: Eat less than you burn and you’ll lose weight. And while it’s possible to lose water weight quickly on a low-carb diet, I certainly wouldn’t advocate for it. The diet itself can trick you into thinking that this eating style is working — when really, you might gain back what you lost as soon as you eat carbs again. That can feel incredibly dispiriting if you want results that last longer than a week. In a way, moderate-intensity physical activity is that "magic pill" a lot of people are looking for, because the health benefits go beyond keeping your waistline trim: Not only can it reduce your risk of cancer, stroke, diabetes and heart attacks, but studies have shown that physical activity can significantly improve the moods of patients with major depressive disorders.
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Q: How to edit mysql table to auto enable created_at and updated_at fields? I have a table consisting of created_at and updated_at fields. I've already created the table without enabling default values. How do I make the 'created_at' field record the datetime of creation(writing will occur only once at time of creation) and 'updated_at' field to fill in the datetime of the moment of the table update. A: create trigger is good solution, but this is for me better ALTER TABLE `table_name` ADD `created_at` timestamp NULL DEFAULT CURRENT_TIMESTAMP, ADD `updated_at` timestamp NULL ON UPDATE CURRENT_TIMESTAMP AFTER `created_at`;
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Ikemen desu ne is a 2011 Japanese television series and a remake of the 2009 South Korean series You're Beautiful. Plot Miko is a 20-year-old girl. She is pure but prone to make mistakes. Since her father, who was a composer, died, grew up at an orphanage with her twin brother Mio Sakuraba. Now, Miko is at a convent dreaming of becoming a nun. But one day, a strange man named Mabuchi asks her to join a famous band called A*N*Jell due to her brother being out of the country. Once she agrees, something bigger than a love triangle starts to evolve, along with other people intertwined in this story. Episodes Cast A*N*Jell Miori Takimoto as Miko Sakuraba / Gemma (female) & Mio Sakuraba (for disguised as male and playing as the real one too); A*N*Jell new vocalist/pianist Yura Furutachi as young Miko Kuu Furutachi as young Mio Yuta Tamamori as Ren Katsuragi A*N*Jell lead vocal & guitarist Riu Tanaka as young Ren Taisuke Fujigaya as Shu Fujishiro A*N*Jell bassist Hikaru Yaotome as Yuuki Hongo A*N*Jell rapper & drummer A*J Entertainment Takashima Masanobu as Ando Hiroshi (president of A*J Entertainment) Yanagisawa Shingo as Mabuchi Hajime (Mio's manager) Katase Nana as RINA Nose Anna as Sawagi Yumiko Others Kojima Haruna as NANA (actress & idol) Tanoshingo as Toru (assistant) Imori Miyuki as Sakuraba Shigeko (Miko & Mio's aunt) Manda Hisako as Mizusawa Reiko (solo singer & Ren's mother) Paparazi reporters Rokkaku Seiji as Deguchi Yamazaki Shigenori as Hashimoto Shimizu Yutaka as Baba A*N*Jell's fans Takahashi Maiko as Misaki Aoi as Nanami Aizumi Moeri as Ayumi Guests Koda Kumi as herself (ep. 1) Aoki Yuko as one of the guests in Mio's welcome party (ep. 1) Kato Sylwia as one of the guests in Mio's welcome party (ep. 1) Tanaka Minami as one of the guests in Mio's welcome party (ep. 1) Ishizaka Koji as Harada (ep. 1) Tani Kanon as a child from the Aozora Gakuen (ep. 1) Honda Miyu as a child from the Aozora Gakuen (ep. 1) Nagashima Terumi as a child from the Aozora Gakuen (ep. 1) Uchida Junki as a child from the Aozora Gakuen (ep. 1) Kasuga Kanon as a child from the Aozora Gakuen (ep. 1) Sasahara Naoki as a child from the Aozora Gakuen (ep. 1) Aoyama Kazuya as a child from the Aozora Gakuen (ep. 1) Yoshida Akane as a child from the Aozora Gakuen (ep. 1) Yashiba Toshihiro as an A.J Entertainment security guard (ep. 2) Uchida Mikako (内田三香子) as a waitress (ep. 3) Yabe Yukiko as a shop assistant (ep. 3) Fujimoto Ryo (藤本涼) as a street clerk (ep. 3) Tsujimoto Yuto (辻本優人) as a photographer (ep. 3) Aoki Kazuyo Masuda Naohiro (升田尚宏) as a newscaster (ep. 4) Katori Shingo as himself Jang Keun-suk as himself (special act ep. 8) Music It was announced that the band A.N.JELL from the TBS drama Ikemen desu ne will make their official debut on October 5, 2011. This band was originally a fictional band for the drama with Johnny’s Entertainment members Tamamori Yuta (Kis-My-Ft2) as Katsuragi Ren, Fujigaya Taisuke (Kis-My-Ft2) as Fukishiro Shu, Hikaru Yaotome (Hey! Say! JUMP) as Hongo Yuki, and actress Takimoto Miori as Sakuraba Mio / Miko. Their debut CD temporary titled A.N.JELL with TBS "Ikemen desu ne" Music Collection, will contain two discs – one including all four songs from the band and the other focusing on the OST of the drama with a special package to add. It will be released in two versions of Limited Edition and Regular Edition with the limited version including an original PV and a unique CD jacket. Also, the first print version of this regular version will enclose a rare CD jacket before Sakuraba was a member. Disc 1 promise futari (ふたり) alone Miss You Disc 2 Ikemen desu ne Main Theme (美男ですね メインテーマ) Girl's Soul Sunrise Shower Youphoria Pursuer Aenaku naru mae ni (会えなくなる前に) Ashita hareru kana (アシタハレルカナ) Moon Knows Run and Dive Sky Sky Sky Let's Play Tag Bad Relations Akegata no niji (明け方の虹) You Are Not My Angel My Formal Crisis The Story Has Not Ended Yet Tobikkiri no ai o komete (とびっきりの愛をこめて) Asagi-iro no yoru (浅葱色の夜) Someone's Sorrow He Is My Hero Yousei no kattou (妖精の葛藤) Kokoro no oku no kata e (心の奥の方へ) Ikemen desu ne Main Theme (美男ですね メインテーマ) (Strings ver.) Aenaku naru mae ni (会えなくなる前に) (Strings ver.) Akegata no niji (明け方の虹) (Strings ver.) References External links Category:Kin'yō Dorama Category:2011 Japanese television series debuts Category:2011 Japanese television series endings Category:Musical television series Category:Japanese television series based on South Korean television series
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Mitogen-activated protein kinase is required for bryostatin 1-induced differentiation of the human acute lymphoblastic leukemia cell line Reh. Bryostatin 1 (bryo 1) is known to induce the differentiation and cell cycle arrest of human lymphoid leukemia cells in vitro. The extracellular signal-regulated kinase (ERK), originally identified as a participant in mitogenic signaling, has recently been implicated in the signaling of cellular differentiation. To examine the role of the ERK/mitogen-activated protein (MAP) kinase pathway in B-lymphoid cell differentiation of the Reh Acute Lymphoblastic Leukemia cell line, the effects of bryo 1 on ERK activation were determined. On bryo 1 treatment, the activity of ERK2 (p42) rapidly increased, with ERK1 (p44) protein levels remaining constant. p44/42 immunoprecipitates from lysates of bryo 1-treated cells had increased their ability to phosphorylate the transcription factor Elk-1. Constitutive AP-1 activity was shown to be potentiated after bryo 1 treatment using electrophoretic mobility shift assays. The protein composition of the AP-1 transcription factor complex activated by bryo 1 was analyzed using supershift analysis with specific antibodies against c-Fos, Fos B, c-Jun, Jun B, and Jun D proteins. Supershift analysis revealed that the bryo 1-induced AP-1 complex was composed predominantly of Fos B and Jun D. Therefore, we evaluated the effects of inhibiting MAP/ERK kinase (MEK) on both DNA binding and cellular differentiation. Treatment of Reh cells with 20 microM PD98059, a specific inhibitor of MEK, inhibited bryo 1-induced ERK activity and DNA binding. Furthermore, PD98059 blocked the bryo 1-induced differentiation of Reh cells, as assessed by a number of features associated with lymphoid differentiation, including changes in morphology, cell growth arrest, attachment, and increased expression of the leukocyte integrin CD11c. Moreover, transient transfection of Reh cells with antisense MAP kinase oligonucleotides blocked bryo 1-induced expression of CD11c. Our analysis also shows that CD11c's gene promoter activity is augmented by bryo 1. Therefore, we conclude that activation of the MEK/ERK signaling pathway is necessary for bryo 1-induced differentiation of the pre-B Acute Lymphoblastic Leukemia cell line Reh.
{ "pile_set_name": "PubMed Abstracts" }
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/** * Copyright (C) 2011 JTalks.org Team * This library is free software; you can redistribute it and/or * modify it under the terms of the GNU Lesser General Public * License as published by the Free Software Foundation; either * version 2.1 of the License, or (at your option) any later version. * This library is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU * Lesser General Public License for more details. * You should have received a copy of the GNU Lesser General Public * License along with this library; if not, write to the Free Software * Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301 USA */ package org.jtalks.jcommune.service.transactional; import org.jtalks.jcommune.model.dao.BranchDao; import org.jtalks.jcommune.model.dao.PostDao; import org.jtalks.jcommune.model.entity.Branch; import org.jtalks.jcommune.model.entity.Post; import org.jtalks.jcommune.service.BranchLastPostService; /** * An implementation of {@link BranchLastPostService} that based * on working with database. It provides an ability to find the * last post in database for branch and save it in the branch field. * * @author Anuar_Nurmakanov * */ public class TransactionalBranchLastPostService implements BranchLastPostService { private PostDao postDao; private BranchDao branchDao; /** * Constructs an instance with required fields. * * @param postDao for getting the last post of the branch * @param branchDao it's needed to update branch */ public TransactionalBranchLastPostService(PostDao postDao, BranchDao branchDao) { this.postDao = postDao; this.branchDao = branchDao; } /** * {@inheritDoc} */ @Override public void refreshLastPostInBranch(Branch branch) { Post lastPostOfBranch = postDao.getLastPostFor(branch); branch.setLastPost(lastPostOfBranch); branchDao.saveOrUpdate(branch); } }
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Q: Query working in SQL client returns no row using PHP and PDO I am really scratching my head because I am trying to figure out why a query that works perfectly in MySQL Client and returns the proper results, has no effect when feeded by PDO. My query is: SELECT id, title, img FROM blog_posts JOIN blog_img ON blog_posts.id = blog_img.id_post WHERE id='1'; and my PHP/PDO code is: $query = $this->dbconn->get_db_access()->prepare("SELECT id, title, img FROM blog_posts JOIN blog_img ON blog_posts.id = blog_img.id_post WHERE id=:id"); $query->bindParam(":id", $id); $result = $query->fetch(PDO::FETCH_ASSOC); print_r($result); No PDOException is thrown and yet the $result array is empty. Can anyone come up with an explaination, please? Is there anything I am doing wrong? Is there a way to "check" the "final" SQL code after the binding and before it gets thrown in so that I make sure everything is ok? A: You are not actually executing the prepared statement. You have to execute it before you try to retrieve data. Try something like this: $sql = "SELECT id, title, img FROM blog_posts JOIN blog_img ON blog_post.id = blog_img.id_post WHERE id=:id"; $stmt = $this->dbconn->get_db_access()->prepare($sql); $stmt->bindParam(':id', $id); $stmt->execute(); $result = $stmt->fetch(PDO::FETCH_ASSOC); Note that prepare() will return a PDOStatement object. You then bind the parameter to the PDOStatment object and execute() the prepared statement. Finally you get the result using fetch().
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Paul Ionescu, County Emergency Hospital of Bacau Masked hypertension is a relatively new entity in the high blood pressure, for which the only way to high­light it is the ambulatory blood pressure ...
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[Biodegradation of [omim][PF6]]. Acclimatized the activated sludge with [omim][PF6] which was used as the C, N, P resources for microbe, the biodegradation ratio of [omim][PF6] with different inoculants which were acclimatized or not was investigated. And the influence of appending an ester in the side chain of the imidazolium cation on the biodegradation of [omim][PF6] was discussed in the same conditions. The biodegradation pathways of [omim]+ were analyzed. The results showed that the biodegradation of ionic liquids was improved by appending an ester in the side chain; the biodegradation rate of [omim][PF6] was less than 20% when the inoculant was original activated sludge, which was not referred as "readily biodegradable"; [omim][PF6] would stay in environment for a long time; the biodegradation ratio reached 60% when the inoculant was acclimatized activated sludge; 1-methyl-imidazolium was residual in the course of biodegradation of [omim]+, the semifinished products of biodegradation of [omim]+ was analyzed by HPLC-MS/MS and the pathways were presumed.
{ "pile_set_name": "PubMed Abstracts" }
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The Covenant Chain and Aboriginal-Crown Relations This book holds up the Covenant Chain, the historical treaty relationship between the British Crown and indigenous people in North America, as a model for building an ethic of mutual respect to guide modern treaty disputes and land claims. This book holds up the Covenant Chain, the historical treaty relationship between the British Crown and indigenous people in North America, as a model for building an ethic of mutual respect to guide modern treaty disputes and land claims.
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MagnificentKaaboom Crowdfunding: You haven't seen a Kickstarter until you've seen the incredibly surreal Magnificent Kaaboom campaign. Legal: NECA/WizKids has obtained a Consent Permanent Injunction against Tree House Kids, which prohibits the use of their "Heroics" minifigure brand...
{ "pile_set_name": "Pile-CC" }
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Ive got a engineer that dispatches a team to repair them when they are damaged. But what are they and how do I even know when they are damaged? Do I just assume that when my hull reaches a certain damage threshold that Im taking system damage? Ive never seen any of my weapons or tech go offline no matter how much damage I took so what exactly is going on with Auxiliary Damage? the engineer repairs disabled subsystems, in this case auxiliary. So if a player or npc uses skills like "disable subsystem XXX" or phaser weapons that can do that too you can get them online again. Auxiliary is needed for many scientific skills, they get better the higher aux, also some engineering skills (auxiliary power to ...). It also increases your turnrate and improves your sensors (when you want to detect cloaked ships), and improves your cloak (when you don't want to get detected) Ive got a engineer that dispatches a team to repair them when they are damaged. But what are they and how do I even know when they are damaged? Do I just assume that when my hull reaches a certain damage threshold that Im taking system damage? Ive never seen any of my weapons or tech go offline no matter how much damage I took so what exactly is going on with Auxiliary Damage? The battery will boost your current power level in Auxiliary. Anything that's affected by your current Aux power will benefit. The four main systems on your ship are not affected by 'normal' damage, but there are several abilities and weapon effects that can disable one or more of them temporarily. If that occurs, your engineering ability should get them up and running again.
{ "pile_set_name": "Pile-CC" }
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Q: How to prune a cherry tree that was left alone since being planted I recently moved into a house with lots of horticultural learning opportunities :) This semi-dwarf cherry was planted at least two years ago and (as far as I can tell) has never been pruned. The picture shows two different angles. For scale, the lowest branches are about knee level: My goal is to have it eventually develop into a healthy, fruit-bearing, backyard-type tree. I don't need to get a harvest any time soon. How should I proceed to get this tree into shape? I've done a lot of reading, but haven't actually done any tree pruning. Also, when should I do this initial pruning? A: SFGATEadvises: Prune approximately 10 percent of the limbs each winter to increase sunlight to the center of the tree and to encourage new growth, which in turn will produce more fruit. Cut damaged, older and the least-productive stems back from where they originate, using pruning shears, loppers or a pruning saw. Thin crowded areas as well. Evenly distribute pruned branches to maintain a nicely shaped tree. In your case ~10% at present seems to mean at most two (whole) branches. The level at which low branches near the trunk will be an obstruction will rise with age but since planted in grass you presumably will be mowing and so may appreciate reasonable headroom, so might want to end up with about 4' of bare trunk. Unless ease of protecting the fruit from birds and harvesting is more important for you (assuming you do not have access to the equipment Woodyatt Cherry Farms has!) in which case you would presumably prefer the canopy as low as possible – see for instance How do I prune a cherry tree to keep it short?. For timing, Stark Bro's advises (about pruning in general): Plan to prune your fruit trees during every dormant season. In Zone 6 and farther north, you should wait until late winter. though also mentions You can have confidence in knowing that not everyone will prune the exact same way (including the “experts”) and with their video (which shows some relevant practical details, like aiming to allow light and air into the centre) offer late winter and early spring, while they are dormant and before their buds break. Pruning is never normally a good idea in a growing season as when the tree is most active the flow of sap is greater, so more energy to waste from leaks and more to attract pests.
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Q: How to synchronize data-attr and select box vaule? I have two elements like: <select id="data"> <option value=1>hoge</option> <option value=2>fuga</option> <option value=3>hogehoge</option> </select> <a href="#1" data-id="1">hoge</a> <a href="#2" data-id="2">fuga</a> <a href="#3" data-id="3">hogehoge</a> if I pick hoge on select box, I want data-id="1" to be selected and do some stuff (changing background etc.) using jQuery. If I click a[data-id="3"], select box option 'hogehoge' to be selected vice versa. any help would be appreciated. A: Have a look at the last line in the click listener. You can trigger a change on an element which will call the corresponding listener instead of duplicating code. $(function() { $("#data").on("change", function() { $("a").removeClass("active"); // remove active class from all <a> $("a[data-id='" + $(this).val() + "']").addClass("active"); // add active class to link with corresponding data-id }); $("a").on("click", function() { $("#data option[value='" + $(this).data("id") + "']").prop("selected", true); // change the selected value $("#data").trigger("change"); // trigger change on #data to keep active link synced }); }); .active { background-color: cornflowerblue; color: white; } <script src="https://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js"></script> <select id="data"> <option value=1>hoge</option> <option value=2>fuga</option> <option value=3>hogehoge</option> </select> <a href="#1" data-id="1" class="active">hoge</a> <a href="#2" data-id="2">fuga</a> <a href="#3" data-id="3">hogehoge</a>
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Q: How to mark posts as edited? I would like to have questions marked as "Edited", but I dont know what the best way to do this would be. Users post a question, people answer/comment on the question, and if necessary the user edits/updates the question (just like SO). I would like to note that the user edited the question, but I'm not sure of the best way to do this. I was going to add a last_edited column in the table (because thats all thats really important to me), but I'm not sure if I should just split the edit times (and whatever else) into another table and record everytime the question gets edited. EDIT: UIf I were to use a timestamp, what time would be used? Is there any way to insert a unix timestmap on update? A: If all what you want is a mark Edited or not, you can just add a Timestamp column in the same table, populated to NULL by default, then populated by last update timestamp. On the page if its populated then display its value, otherwise don't display the Edited icon/symbol.
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19 Mich. App. 266 (1969) 172 N.W.2d 550 PEOPLE v. HUMMEL Docket No. 4,324. Michigan Court of Appeals. Decided October 1, 1969. Frank J. Kelley, Attorney General, Robert A. Derengoski, Solicitor General, S. Jerome Bronson, Prosecuting Attorney, Dennis Donohue, Chief Appellate Counsel, and Bruce T. Leitman, Assistant Prosecuting Attorney, for the people. Philip G. Ingraham, for defendant. Before: LESINSKI, C.J., and QUINN and MOODY,[*] JJ. *268 MOODY, J. On March 2, 1953, the defendant Harold Hummel was convicted by jury verdict of the first-degree murders[1] of Joseph Vinokurow and Vidos Vinokurow. Certain oral admissions were introduced at trial, as well as a written confession which was given to the Oakland county prosecutor. The defendant filed an application for leave to appeal, and this Court granted his motion and remanded the case to the Oakland county circuit court for a Walker hearing[2] concerning the voluntariness of the confessions. On July 5, 1967, the judge who conducted the hearing filed an opinion in which he concluded that the admissions and confessions were voluntarily made and were properly admitted into evidence during the defendant's trial. On this appeal the problem presented is what standard of review will be used when defendant contests the outcome of a Walker hearing. In People v. Walker (1967), 6 Mich App 600, 602, this Court stated it would only reverse a finding that the confession was voluntary, if the trial court's finding was "clearly erroneous". The reason was based on an interpretation of GCR 1963, 785.1 and GCR 1963, 517.1. In two later cases, People v. Pallister (1968), 14 Mich App 139, 141, and People v. Summers (1968), 15 Mich App 346, 348, the Court stated it must "`examine the entire record and make an independent determination of the ultimate issue of voluntariness'". While this may appear to differ from the "clearly erroneous" test, in fact they are the same. The relation between the two verbal formulations is made quite clear in 2 Honigman & Hawkins, Michigan Court Rules Annotated, (2d ed), Rule 517, where the authors note at p 596: *269 "Formerly in chancery cases, although it was commonly said that issues of fact were tried de novo on appeal or that the Supreme Court must weigh the evidence and reach an independent conclusion on review of the facts, this did not mean that the findings of the trial judge were entitled to no consideration. Notwithstanding the right and duty of the Supreme Court to make its independent evaluation of the evidence, it would not set aside the findings of the trial judge unless it was convinced that a clear showing of error had been made. Running through the opinions are phrases such as `clear error', `manifest error', `palpably erroneous'. See MLP, Appeal, § 382 and Michigan decisions infra. Especially when there was a sharp conflict in the evidence, the reviewing court would not disturb the trial court's determination of fact questions, unless it was clear that a wrong conclusion had been reached. The Supreme Court was most reluctant to disturb the findings of a trial judge based on credibility, since the trial judge, as the trier of facts, had the advantage of observing the witness. "Thus it is clear that Rule 517 accurately restates former practice in the review of chancery cases in Michigan, although the language itself is borrowed from Federal Rule 52. The most frequently quoted explanation of the `clearly erroneous' standard in Federal Rule 52(a) is contained in United States v. United States Gypsum Co. (1948), 333 US 364, 395 (68 S Ct 525, 542, 92 L Ed 746), reh. den. 333 US 869 (68 S Ct 788, 92 L Ed 1147): "`Since judicial review of findings of trial courts does not have the statutory or constitutional limitations of findings by administrative agencies or by a jury, this Court may reverse findings of fact by a trial court where "clearly erroneous". The practice in equity prior to the present rules of civil procedure was that the findings of the trial court, when dependent upon oral testimony where the candor and credibility of the witnesses would best be judged, had *270 great weight with the appellate court. The findings were never conclusive, however. A finding is "clearly erroneous" when although there is evidence to support it, the reviewing court on the entire evidence is left with the definite and firm conviction that a mistake has been committed.'" (See People v. Summers at p 348.) Thus, this Court will give deference to trial courts' findings, especially where the demeanor of the witnesses is important, as where credibility is a major factor. However, while the trial court's findings will guide us, we are not bound by them.[3] It is apparent that the Court in Pallister and Summers was applying the "clearly erroneous" standard as set forth above. In Pallister the Court wrote, beginning at p 141: "We are left with the `definite and firm conviction' the trial judge erred * * * and, accordingly, have concluded that the trial judge's finding of voluntariness was clearly erroneous." And in Summers at p 356 it was concluded: "we are convinced that the confession * * * was involuntary". Defendant appeals, claiming the trial court erred in finding upon conclusion of the evidentiary hearing that his statements and confessions were freely and voluntarily made. This Court takes the view, however, that the dispositive issue is whether the judge who presided over the Walker hearing used the proper standard in judging defendant's credibility. The transcript shows that the judge asked Hummel whether he was guilty of the murders. Hummel refused *271 to answer and the trial judge made the following statement: "The Court: Let me say this to you, Mr. Hummel, I am aware of the fact that your refusal to answer this question will be contempt of court, and I am also aware of the fact that there is no punishment which I could administer to one in your position at the present time to enforce your compliance with the court order, or to aid you in purging yourself of contempt. So I will not repeat the question further unless you choose to answer it voluntarily as I have directed you. But I will say this to you and I think you should know it, if you choose not to follow the instructions of the court, if you choose not to answer the question after I have told you that your action would be contemptuous, then I will have to consider this as going to the credibility of your entire testimony today, for when a witness is unwilling to testify and flouts the direction of the court, this impenges [sic] upon the credibility of that witness in my judgment." It is our view that the sole function of a Walker hearing is to determine the voluntariness of a confession, and it is improper to weigh defendant's credibility in light of his innocence or guilt. This follows from the language of People v. Walker (On Rehearing, 1965), 374 Mich 331, 338, which construed Jackson v. Denno (1964), 378 US 368 (84 S Ct 1774, 12 L Ed 2d 908), as follows: "We therefore release our jursdiction of the cause and direct the recorder's court to assume jurisdiction to make a determination upon a separate record upon the issue of the voluntariness of the confession only. At this hearing, we hold the defendant may take the stand and testify for the limited purpose of making of record his version of the facts and circumstances under which the confession was obtained. We hold further that by so doing defendant does *272 not waive his right to decline to take the stand on trial in chief, if retrial is ordered. Neither does he waive any of the other rights stemming from his choice not to testify. This we believe comports with the apparent intention of Jackson, supra, to require the issue of the voluntariness of a confession to be determined completely apart from and independent of the consideration of that issue by the jury which is considering guilt or innocence under established procedures." It was error for the trial judge to allow the issue of guilt to enter into the evidentiary hearing on the issue of voluntariness of the defendant's statements and confessions. In view of the fact that credibility of the defendant is of great importance at such a hearing and an improper standard was employed in judging defendant's credibility, we hereby remand the cause to the trial court for a new evidentiary hearing on the issues as previously ordered. It might be argued that in the course of our independent determination we can ignore the errors made below, thus making a new Walker hearing unnecessary. However, since we are guided by the findings of the trial court, we should have an opinion by it before us which is based on a hearing free of substantial error. Under the circumstances of this case we deem it advisable that some other judge of this multi-judge circuit conduct the rehearing. It is ordered that the presiding judge of the circuit designate the judge for the rehearing. Remanded for proceedings consistent with this opinion. We retain no further jurisdiction in this cause. All concurred. NOTES [*] Circuit Judge, sitting on the Court of Appeals by assignment. [1] CL 1948, § 750.316 (Stat Ann 1954 Rev § 28.548). [2] People v. Walker (On Rehearing, 1965), 374 Mich 381. [3] This, of course, is a significantly different test than the standard of review of a jury's finding. A jury's finding of fact will be affirmed if there is sufficient evidence to lead a reasonable man to come to the same conclusion. Under the "clearly erroneous" standard, however, a trial judge can be reversed even though there was sufficient evidence to lead a reasonable man to the same result, if we are of "the definite and firm conviction that a mistake has been committed".
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Occupational exposure to non-artificial UV-light and non-melanocytic skin cancer - a systematic review concerning a new occupational disease. Although UV exposure is the most important risk factor for cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), a systematic review analyzing the risk of occupational UV exposure is missing. Based on a systematic literature search in PubMed (until 05/2009) supplemented by hand search, the association between occupational UV exposure and SCC and BCC was analyzed. Literature search and data abstraction was done independently by 2 reviewers. The association between occupational UV exposure and cancer risk is presented as odds ratios (OR). We identified 25 relevant epidemiologic studies (5 cohort studies, 17 case-control studies, 3 cross-sectional studies). 12 studies described a positive association between occupational UV exposure and risk of SCC with OR > 3 in 6 studies and OR 1.5-2.0 in another 6 studies. 3 studies did not find a relevant association (OR: 1.0-1.4). A significant positive association between occupational UV exposure and BCC was reported in 5 studies; 11 studies did not find a significant association. The association between occupational UV exposure and SCC is well and consistently documented epidemiologically (approximately 2-fold increased risk), so that the criteria for a new occupational disease are fulfilled. The association with BCC is unclear due to significant methodological limitations in the published studies.
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Dear all: A few words about Tom. He is a power engineer type who has previously worked at northwestern US and New Zealand utilities on various projects including asset planning and hydro scheduling. He was hired by EI Structuring to oversee modeling efforts using SDDP, Henwood, etc. Because of the recent implosion at EI APACHE, Tom's group has effectively evaporated, and thus he is looking for a new home. He has some finance background from having to do asset evaluation for utility rate filings. He has almost no options experience. He seems to have quite a bit of experience in some classes of OR problems. Clearly the most obvious fit is with my group, but the idea is for you all to see if Tom has a tool set that may be of use to other research projects. And, as usual, the personality fit is the other aspect to examine. This is meant to be casual. If the consensus is positive, then I will explore the formalities of such a transfer. Thanks, Grant.
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Q: Searching for date range or null/no field in Solr I want to perform a search on a text field in Solr. I want to return all matches in a range or where there is no value. The two searches word independently: myfield:[start TO finish] -myfield:[* TO *] The first returns all matches in the range. The second returns all matches that have no value for the "myfield" field. The problem is combining these two. This returns no matches: myfield:[start TO finish] OR -myfield:[* TO *] This returns matches between start and finish, but not null entries: myfield:[start TO finish] OR (-myfield:[* TO *]) A: The solution from Mauricio Scheffer worked for me until I've included it into full query. The query itself may contain up to three fields with ranges and somewhere in the middle Solr failed to process it. I have managed to solve it with next query: (myfield:[start TO finish] OR (*:* NOT myfield:[* TO *])) It woked even in my complex query, so maybe it will help someone else.
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Fifty-nine of New Jersey’s wealthiest school districts would receive no direct state aid for their operations next year — in effect, a 100 percent cut — under the governor’s proposed budget, according to state figures released on Wednesday. The state would seek to reduce direct aid to nearly 600 districts by an amount equivalent to as much as 5 percent of their individual operating budgets, for an overall reduction of $820 million from the year before. The education cuts were revealed in detail for the first time since being proposed on Tuesday by Gov. Christopher J. Christie as part of his $29.3 billion budget plan. For wealthier districts like Ridgewood, Millburn and Glen Ridge, that would mean losing the direct state aid that they receive for their classrooms — a relatively small percentage of their operating budget — forcing them to rely almost exclusively on local property taxes. “It is by no means a death blow, but it is a heavy burden,” said Elisabeth Ginsburg, the school board president in Glen Ridge, which received $1.2 million in state aid this year, most of which paid for mandated special-education services. “You have to think carefully about how you’re going to go forward.”
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Germany has extradited back to Sweden a convicted killer known as “the laser man” for using a precision-scope rifle to target immigrants. John Ausonius, 65, a Swedish far-right extremist, has been found guilty of murder in both countries, most recently receiving a life term in Germany in February last year that was upheld on appeal in November. He previously received a life sentence in Sweden for a six-month shooting spree in 1991-92. Using the laser-scoped rifle, he killed a 34-year-old Iranian man and wounded 10 other people from countries including Brazil, Greece, Syria and Zimbabwe. In a sign of Ausonius’s notoriety, the Norwegian white supremacist mass murderer Anders Behring Breivik mentioned the “laser man” as a figure who shared the same goals during his own trial. Ausonius was extradited to Germany in late 2016, and in February 2018 he was found guilty of the 1992 murder of a 68-year-old Jewish Holocaust survivor, Blanka Zmigrod, in Frankfurt. Having now received life terms in two countries, Ausonius is considered almost certain to spend the rest of his life locked up without parole.
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fantasy sports advice Main Menu Ace Picks: 2016 Wild Card This was a great season for picks, even though there were more surprises than a few. Picking the Cowboys (without Tony Romo) to beat the Redskins, and the Eagles to take out the Patriots, were two of my favorites of the year. And the last week of the year was no different, with several picks going my way, like the Broncos beating the Chargers, the Vikings taking out the Packers, and the Chiefs emerging victorious against the Raiders. But now we’re dealing with a different kind of beast — the playoffs. This is the time when a #6 seed can run the tables and win the whole thing, or they can lose in the first round to the #3 and go home early. It’s also the time when the loss of a running game can be most important (Pittsburgh), and when even strong defenses are tested (Houston). The Patriots are lucky they have another week to get healthy, but the Bengals are starting AJ McCarron again this week hoping to get their first playoff win in five tries. Here are my Ace Picks for the Wild Card Round… AFC #5 KANSAS CITY @ #4 HOUSTON – Both teams are hot right now, and the Texans get Brian Hoyer back as they host the Chiefs in Houston. These teams are well-matched with two excellent defenses and offenses that are good enough without being great. The Chiefs have been here before and not done well, but this year they have Jeremy Maclin, who stretches the field, and a two-headed running back system that can pound it inside. Pick: KANSAS CITY. #6 PITTSBURGH @ #3 CINCINNATI – A.J. Green plays for the Bengals, and he seems to have already developed a good rapport with AJ McCarron, but the team from Cincinnati runs through its backs, and Jeremy Hill is rounding into form at the right time. The Steelers laid a big egg in week 16, and weren’t great in week 17, so they’re trending the wrong way right now. They’re a trendy pick to advance, but the Bengals will force a few turnovers that will be the difference in the end. Pick: CINCINNATI. NFC #6 SEATTLE @ #3 MINNESOTA – Speaking of trendy picks, apparently most experts have forgotten how poorly the Seahawks played to start the season, and the egg they laid of their own in week 16. The Vikings come in hot off a demolition of the Packers in Green Bay, but Seattle has the superior defense, and their offense isn’t one-dimensional. I want to call this a win for the Vikings, but short of a few turnovers I don’t see it happening, even in an “early” game. Pick: SEATTLE. #5 GREEN BAY @ #4 WASHINGTON – The Redskins are one of the hottest teams in the NFL right now, and even though they play in the NFC East I think they the game suited for a bit of a playoff run. On the reverse side, the Packers have just not been “right” of late, and I don’t see anything changing here. The key is that they’ve been dysfunctional offensively, and even against that Redskins defense I don’t see them outslinging Kirk Cousins and his high wire show. Pick: WASHINGTON.
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While Americans were freezing their Tebows off watching playoff football, the first major tennis tournament of the year kicked off in Australia, with temperatures in Melbourne hitting 92 on day one. Dylan Stableford, Deadspin's tennis editor, has a preview of the action Down Under.»1/16/12 2:05pm 1/16/12 2:05pm
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*(9*a - 2)**2/3 Factor -54*o**2/7 - 158*o/7 + 12/7. -2*(o + 3)*(27*o - 2)/7 Factor 4*z**5 - 28*z**4 - 4*z**3 + 28*z**2. 4*z**2*(z - 7)*(z - 1)*(z + 1) Factor -4*o**2/5 + 5896*o/5 - 2172676/5. -4*(o - 737)**2/5 Let 3*y**3 - 9*y**2 - 39*y + 45 = 0. What is y? -3, 1, 5 Factor 2*o**3 + 1478*o**2 - 2*o - 1478. 2*(o - 1)*(o + 1)*(o + 739) Let 4*q**4/9 - 1132*q**3/9 - 760*q**2/3 = 0. Calculate q. -2, 0, 285 Suppose -2*n**3/5 + 42*n**2/5 + 248*n/5 + 312/5 = 0. What is n? -3, -2, 26 Factor 2*k**3 - 258*k**2 + 11094*k - 159014. 2*(k - 43)**3 Find c such that -2*c**4 - 100*c**3 - 1706*c**2 - 11400*c - 25992 = 0. -19, -6 Find q, given that -4*q**5/5 - 7*q**4/5 + 14*q**3/5 + 29*q**2/5 + 8*q/5 - 4/5 = 0. -2, -1, 1/4, 2 Solve -5*x**3/7 + 12*x**2/7 - 9*x/7 + 2/7 = 0 for x. 2/5, 1 Factor 75*n**4/7 + 960*n**3/7 + 3432*n**2/7 + 2304*n/7 + 432/7. 3*(n + 6)**2*(5*n + 2)**2/7 Solve -2*s**4 - 1566*s**3 - 305760*s**2 + 307328*s = 0. -392, 0, 1 Factor w**4 - 3*w**3 - 2*w**2 + 12*w - 8. (w - 2)**2*(w - 1)*(w + 2) Determine z, given that -3*z**2 + 27*z - 60 = 0. 4, 5 Determine r so that 5*r**2/2 + 8175*r/2 = 0. -1635, 0 Factor 10*s**2/9 + 128*s/3 + 152/9. 2*(s + 38)*(5*s + 2)/9 Factor 3*o**3 - 18*o**2 - 75*o - 54. 3*(o - 9)*(o + 1)*(o + 2) Let 12*f**4 - 880*f**3 + 17512*f**2 - 49840*f + 14700 = 0. Calculate f. 1/3, 3, 35 Suppose -q**5 - 11*q**4 + 15*q**3 + 35*q**2 - 14*q - 24 = 0. What is q? -12, -1, 1, 2 Factor -3*v**3 + 168*v**2 - 1188*v + 1728. -3*(v - 48)*(v - 6)*(v - 2) Suppose -3*s**5/5 - 33*s**4/5 - 126*s**3/5 - 42*s**2 - 159*s/5 - 9 = 0. Calculate s. -5, -3, -1 Factor 3*n**2/7 + 1581*n. 3*n*(n + 3689)/7 Factor 4*o**3/3 - 180*o**2 + 528*o. 4*o*(o - 132)*(o - 3)/3 Solve z**3/3 - 14*z**2/3 + 35*z/3 - 22/3 = 0. 1, 2, 11 Let 3*w**4/4 + 3*w**3/4 - 171*w**2/4 - 3*w/4 + 42 = 0. Calculate w. -8, -1, 1, 7 Factor 3*f**4 - 6*f**3 - 369*f**2 - 1740*f - 2100. 3*(f - 14)*(f + 2)*(f + 5)**2 Find q, given that -5*q**3/3 - 2265*q**2 - 1026045*q - 154932795 = 0. -453 Solve -2*n**3/7 - 46*n**2/7 - 268*n/7 - 32 = 0 for n. -14, -8, -1 Factor 3*f**3 - 13*f**2 + 55*f/3 - 25/3. (f - 1)*(3*f - 5)**2/3 Find w, given that -3*w**4/5 - 132*w**3/5 - 1314*w**2/5 + 3036*w/5 - 1587/5 = 0. -23, 1 Solve -h**5/6 + h**4/2 - h**3/6 - h**2/2 + h/3 = 0 for h. -1, 0, 1, 2 Factor -6*v**3 - 237*v**2 - 99*v + 702. -3*(v + 2)*(v + 39)*(2*v - 3) Determine b, given that b**4/2 + 47*b**3/2 - 51*b**2 - 9920*b - 19456 = 0. -32, -2, 19 Factor -5*w**2/6 - 10*w/3 - 5/2. -5*(w + 1)*(w + 3)/6 Factor -3*c**2/8 + 1779*c/8 - 1773/4. -3*(c - 591)*(c - 2)/8 Factor 2*g**4 + 18*g**3 - 2*g**2 - 18*g. 2*g*(g - 1)*(g + 1)*(g + 9) Let j**2 - 122*j + 3721 = 0. What is j? 61 Solve h**2/5 + 31*h/5 - 32/5 = 0. -32, 1 Factor -2*f**4/3 + 2*f**3/3 + 8*f**2. -2*f**2*(f - 4)*(f + 3)/3 Factor -25*m**2 + 10*m. -5*m*(5*m - 2) Factor 4*d**3 - 68*d**2 + 56*d + 128. 4*(d - 16)*(d - 2)*(d + 1) Suppose 3*i**5/2 - 119*i**4 + 271*i**3 - 114*i**2 - 233*i/2 + 77 = 0. Calculate i. -2/3, 1, 77 Factor r**2/4 + 885*r/4. r*(r + 885)/4 Factor 2*q**5/5 + 8*q**4 - 42*q**3/5. 2*q**3*(q - 1)*(q + 21)/5 Factor 2*b**2 + 192*b + 4608. 2*(b + 48)**2 What is t in 20*t**5 + 176*t**4 - 836*t**3 - 560*t**2 + 3024*t - 576 = 0? -12, -2, 1/5, 2, 3 Factor 33*j**3/2 - 162*j**2 + 366*j + 72. 3*(j - 6)*(j - 4)*(11*j + 2)/2 Solve 2*l**5/5 + 11*l**4/10 - 79*l**3/10 + 7*l**2/10 + 15*l/2 - 9/5 = 0. -6, -1, 1/4, 1, 3 Factor 3*q**2 - 228*q + 225. 3*(q - 75)*(q - 1) Factor -u**5 - 7*u**4 + 3*u**3 + 55*u**2 - 50*u. -u*(u - 2)*(u - 1)*(u + 5)**2 Find y such that -2*y**4 + 6*y**3 + 22*y**2 - 6*y - 20 = 0. -2, -1, 1, 5 Factor 4*o**2 - 3540*o - 3544. 4*(o - 886)*(o + 1) Factor 4*s**5 - 93*s**4 + 23*s**3. s**3*(s - 23)*(4*s - 1) Factor 5*n**2 + 2650*n + 351125. 5*(n + 265)**2 Let -26*w**5/3 - 158*w**4/3 + 274*w**3/3 + 1582*w**2/3 - 2480*w/3 - 200/3 = 0. Calculate w. -5, -1/13, 2 Solve -3*o**3 + 189*o**2 + 390*o = 0. -2, 0, 65 Factor s**3 - 64*s**2/3 + 319*s/3 + 242/3. (s - 11)**2*(3*s + 2)/3 Find u, given that -2*u**3/3 + 522*u**2 - 101920*u - 307328/3 = 0. -1, 392 Determine d, given that -4*d**2/3 - 1120*d + 3372 = 0. -843, 3 Factor -k**2 - 259*k. -k*(k + 259) Factor 6*m**3 - 596*m**2 + 194*m + 396. 2*(m - 99)*(m - 1)*(3*m + 2) Factor -3*p**3 + 144*p**2 - 2304*p + 12288. -3*(p - 16)**3 Factor -4*p**2/7 - 40*p/7. -4*p*(p + 10)/7 Let 5*a**5 + 420*a**4 - 4535*a**3 + 15310*a**2 - 18720*a + 7520 = 0. Calculate a. -94, 1, 4 Factor 28*g**2 - 10060*g + 2872. 4*(g - 359)*(7*g - 2) What is c in -2*c**2/7 + 542*c/7 + 544/7 = 0? -1, 272 Determine m, given that m**2/5 + 2*m/5 + 1/5 = 0. -1 Let -b**2/7 + 60*b/7 - 900/7 = 0. Calculate b. 30 Factor -3*h**2 + 2421*h + 2424. -3*(h - 808)*(h + 1) Find p, given that 2*p**4/13 - 176*p**3/13 - 548*p**2/13 + 176*p/13 + 42 = 0. -3, -1, 1, 91 Factor 4*x**5 + 16*x**4 + 24*x**3 + 16*x**2 + 4*x. 4*x*(x + 1)**4 Solve 20*k**5 - 368*k**4 + 1104*k**3 - 1304*k**2 + 668*k - 120 = 0 for k. 2/5, 1, 15 Factor -3*w**2 + 12*w. -3*w*(w - 4) Factor 4*x**3/3 - 32*x**2/3 + 20*x/3 + 56/3. 4*(x - 7)*(x - 2)*(x + 1)/3 What is l in l**3/4 + 367*l**2/4 + 34571*l/4 + 163805/4 = 0? -181, -5 Factor -g**2/4 - 119*g/4 + 30. -(g - 1)*(g + 120)/4 Factor -o**3/2 + 11*o**2 + o/2 - 11. -(o - 22)*(o - 1)*(o + 1)/2 Factor 2*j**2/9 + 4*j/3. 2*j*(j + 6)/9 What is q in 224*q**4 + 2600*q**3 - 1076*q**2 - 236*q + 48 = 0? -12, -1/4, 1/7, 1/2 Factor -r**3/4 - 37*r**2/4 - 41*r - 32. -(r + 1)*(r + 4)*(r + 32)/4 Find w such that w**2 + 19*w - 42 = 0. -21, 2 Determine d so that 4*d**5/5 - 17*d**4/5 + 12*d**3/5 + 14*d**2/5 - 16*d/5 + 3/5 = 0. -1, 1/4, 1, 3 Factor u**4/6 - u**3/3 + u/3 - 1/6. (u - 1)**3*(u + 1)/6 Factor 3*s**2 + 87*s + 570. 3*(s + 10)*(s + 19) Factor 3*f**2/4 + 375*f + 46875. 3*(f + 250)**2/4 Determine a so that -2*a**5/7 - 22*a**4/7 + 60*a**3/7 + 100*a**2/7 - 58*a/7 - 78/7 = 0. -13, -1, 1, 3 Factor y**5/4 + 5*y**4/2 + 39*y**3/4 + 37*y**2/2 + 17*y + 6. (y + 1)*(y + 2)**3*(y + 3)/4 Factor 2*q**2 + 96*q - 98. 2*(q - 1)*(q + 49) Suppose 2*v**3/17 + 14*v**2 + 7198*v/17 + 6962/17 = 0. What is v? -59, -1 Factor -u**3 + 5*u**2 + 14*u. -u*(u - 7)*(u + 2) Let 26*d**5 - 186*d**4 + 158*d**3 + 162*d**2 - 184*d + 24 = 0. Calculate d. -1, 2/13, 1, 6 Factor -o**3/4 + 31*o**2/4 - 255*o/4 + 225/4. -(o - 15)**2*(o - 1)/4 Find i, given that -2*i**4 + 12*i**3 - 18*i**2 = 0. 0, 3 Solve -4*r**2 + 140*r + 800 = 0 for r. -5, 40 Solve -4*r**3/5 - 84*r**2/5 - 152*r/5 = 0 for r. -19, -2, 0 Suppose 3*a**5/2 - 303*a**4 + 1782*a**3 - 3540*a**2 + 2352*a = 0. Calculate a. 0, 2, 196 Factor 3*o**3 - 39*o**2 - 270*o. 3*o*(o - 18)*(o + 5) Let -7*t**4 + 772*t**3 - 9971*t**2 + 35714*t - 9408 = 0. What is t? 2/7, 7, 96 Factor -3*u**5 + 24*u**3 - 48*u. -3*u*(u - 2)**2*(u + 2)**2 Factor 4*v**5/3 + 404*v**4/3 + 796*v**3/3 + 132*v**2. 4*v**2*(v + 1)**2*(v + 99)/3 Determine b, given that 9*b**4/5 - 34*b**3/5 - 8*b**2/5 = 0. -2/9, 0, 4 Suppose 2*k**2/7 - 216*k/7 + 214/7 = 0. What is k? 1, 107 Solve -4*w**5 + 76*w**4 - 124*w**3 - 236*w**2 + 560*w - 272 = 0 for w. -2, 1, 2, 17 Let -2*j**4 - 2*j**3 + 60*j**2 = 0. Calculate j. -6, 0, 5 What is h in -48*h**4/7 - 242*h**3/7 - 346*h**2/7 - 158*h/7 - 6/7 = 0? -3, -1, -1/24 Determine a, given that 95*a**3/7 + 258*a**2/7 - 227*a/7 - 18 = 0. -63/19, -2/5, 1 Factor 4*u**3/5 - 1032*u**2/5 + 88752*u/5 - 2544224/5. 4*(u - 86)**3/5 Factor -2*p**4/17 + 16*p**3/17 + 18*p**2/17. -2*p**2*(p - 9)*(p + 1)/17 Factor -5*i**5 - 5*i**4 + 5*i**3 + 5*i**2. -5*i**2*(i - 1)*(i + 1)**2 Find r, given that -12*r**5 + 432*r**4 + 1377*r**3 + 1053*r**2 = 0. -3/2, 0, 39 Factor 3*h**3/5 + 51*h**2/5 + 237*h/5 + 189/5. 3*(h + 1)*(h + 7)*(h + 9)/5 Solve 2*f**4/3 - 8*f**3 - 40*f**2 + 1600*f/3 = 0. -8, 0, 10 Suppose 8*x**5/5 + 56*x**4/5 - 294*x**3/5 - 544*x**2/5 - 22*x/5 + 36 = 0. What is x? -10, -1, 1/2, 9/2 Solve -5*b**5 - 415*b**4 - 10310*b**3 - 71730*b**2 - 194805*b - 184815 = 0. -37, -3 Let 4*d**5 + 52*d**4 + 180*d**3 - 100*d**2 - 1000*d = 0. What is d? -5, 0, 2 Factor -4*q**2/5 - 96*q - 476/5. -4*(q + 1)*(q + 119)/5 Factor -y**4/4 + y**3/4 + 3*y**2/4 - 5*y/4 + 1/2. -(y - 1)**3*(y + 2)/4 Factor h**3/4 + 45*h**2/4 + 271*h/2 + 228. (h + 2)*(h + 19)*(h + 24)/4 Factor -3*w**5 + 54*w**4 - 312*w**3 + 816*w**2 - 1008*w + 480. -3*(w - 10)*(w - 2)**4 Determine o so that -o**2 + 8*o + 20 = 0. -2, 10 Solve 3*h**3/7 - 57*h**2/7
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Deuterophysa purpurealis Deuterophysa purpurealis is a moth in the family Crambidae. It was described by George Hampson in 1913. It is found in Colombia. References Category:Moths described in 1913 Category:Pyraustinae
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Show HN: PWA, SSR for a demo modern web app - revskill https://www.resta.us ====== sotaan can you show your code please? seems like you are using Vue 2
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ESA/Hubble heic1401: Pandora's magnifying glass — First image from Hubble's Frontier Fields. This image of Abell 2744 is the first to come from Hubble's Frontier Fields observing programme, which is using the magnifying power of enormous galaxy clusters to peer deep into the distant Universe. Abell 2744, nicknamed Pandora's Cluster, is thought ... This image of Abell 2744 is the first to come from Hubble's Frontier Fields observing programme, which is using the magnifying power of enormous galaxy clusters to peer deep into the distant Universe. Abell 2744, nicknamed Pandora's Cluster, is thought to have a very violent history, having formed from a cosmic pile-up of multiple galaxy clusters. 7 January 2014: Three-dimensional (3D) printers are transforming the business, medical, and consumer landscape by creating a vast variety of objects, including aeroplane parts, lamps, jewellery, and even artificial human bones. Now astronomers ...
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An automated analyzer for clinical laboratory test dispenses fixed amounts of a specimen and a reagent to cause a reaction, measures the absorbance of a reaction solution for a fixed period of time, and obtains a laboratory test value (the concentration or activity value) of a substance to be measured and the like on the basis of a measurement result. A rate method that is one of measurement methods for clinical laboratory test is mainly used to measure the activity value of an enzyme component contained in a specimen. The measurement method includes adding a fixed amount of a substrate as a reagent and measuring an element that changes when an enzyme consumes the substrate. Generally, a reagent contains a sufficient amount of a substrate. For this reason, if a reaction between a specimen and a reagent is normally being carried out, the reaction is generally such that absorbance changes linearly with time in increments of a fixed amount. In the rate method, the activity value of a substrate to be measured is obtained from the slope of such a straight line (reaction rate). However, there may be a curve part called a lag phase before a reaction rate becomes constant (linear) due to factors such as a measurement item, the concentration of a sample, stirring status, and reaction temperature. In the case of, e.g., a high-activity sample, a reaction may progress fast. In this case, the amount of a substrate in a reagent may become insufficient during measurement, and a reaction rate in a second half may be inconstant. That is, the reaction rate in the second half may change non-linearly (in a curved manner). As described above, a curve part may appear in reaction curve data at the beginning and at a later part of a reaction. For this reason, a conventional device adopts a process of setting a time range used for laboratory test value conversion and an absorbance limit value (Abs limit) for each item. Some of conventional devices have a function for checking linearity called a linearity check. In a linearity check, the difference between amounts of change in absorbance in a first half and a second half of a fixed photometric range is calculated, and change in absorbance is determined to be not linear if the difference is above a designated linearity check value. If the change in absorbance is determined to be not linear, a conventional device makes a notification of “abnormality.” Methods for determining a time range (line range) used for laboratory test value conversion include the methods disclosed in Patent Literatures 1 and 2. Patent Literature 1 discloses a process of calculating an absorbance difference between each pair of adjacent photometric points, setting as a reference point a range between one having the largest absorbance difference (dmax) among the pairs, and determining as a line range sections having absorbance differences that are not less than 80% of the absorbance difference (dmax) of the reference point among sections within a measurement range straddling the reference point. Patent Literature 2 discloses a process of setting the width of a range used for conversion to a fixed width, calculating a coefficient of correlation among absorbance corresponding to the range by the least squares method while shifting the range by one point at a time, starting from a top photometric point, and determining a range with the best correlation as a line range. In recent years, there has been a need to report a result of measuring patient samples as soon as possible in the field of clinical laboratory testing in hospitals. The reaction time period during measurement of an automated analyzer is about 10 minutes. However, simply shortening a measurement time period prevents acquisition of precise results. For example, if measurement is ended at a time when a reaction is incomplete, and a laboratory test value is measured from the absorbance at the time, a precise result is not obtained. To cope with this, it is conceivable to predict the absorbance at the end of a reaction and convert the absorbance to a laboratory test value. As a method for predicting the absorbance at the end of a reaction, Patent Literature 3 is publicly known. A process of approximating reaction curve data using an approximation formula indicated by (Expression 1) and obtaining, in the case of a rate method, the slope of a straight line from two predetermined points or one predetermined point after differentiation of the approximation formula with respect to time is disclosed in Patent Literature 3. Note that, in (Expression 1), t represents a time, y represents absorbance, and that A, B, and K are parameters.y=A+(B−A)/eKt  (Expression 1)
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Transconjunctival sutureless vitrectomy has gained popularity in recent years. The use of 25-gauge or 23-gauge instruments showed many advantages over the conventional 20-gauge vitrectomy system, and there were many reports on the safety and efficacy of 25-gauge or 23-gauge vitrectomy for a variety of vitreoretinal diseases.\[[@CIT1][@CIT2]\] However, the complications involving those small-gauge instruments remain problematic.\[[@CIT3]--[@CIT5]\] We experienced presumed sclerotomy site hemorrhage inflowing into the anterior chamber following the removal of the 23-gauge microcannula in 23-gauge sutureless vitrectomy. Case Reports {#sec1-1} ============ Case 1 {#sec2-1} ------ A 57-year-old man with diabetes was diagnosed with inferotemporal pseudophakic rhegmatogenous retinal detachment with a retinal tear at the 11 o'clock position in the right eye. Best-corrected visual acuity (BCVA) was 20/200 and the axial length was 22.86 mm. Vitreous surgery was carried out using a 23-gauge vitreous cutter driven by a vitrectomy unit (Associate 2500, DORC International, The Netherlands) and the DORC two-step system (DORC International). The procedure was started with a scleral tunnel incision radial to the limbus, as Eckardt described.\[[@CIT2]\] During the surgery, there were no specific events such as hemorrhages. Endolaser photocoagulation and air-gas (12% C~3~F~8~) exchange were performed. At the end of the surgery, the three microcannulae were withdrawn from the scleral tunnel and the immediate postoperative tactile intraocular pressure (IOP) felt normal \[[Fig. 1A](#F0001){ref-type="fig"}\]. About 15 s after removal of the cannulae, the anterior chamber hemorrhage was noticed \[[Fig. 1B](#F0001){ref-type="fig"}\]. It was rapidly inflowing from inferotemporal area of the chamber into the whole space. In addition, there were severe subconjunctival hemorrhages and chemosis in the inferotemporal sclerotomy site \[[Fig. 1C](#F0001){ref-type="fig"}\]. Surgery was completed without any additional procedure. Postoperatively, we could not find any vitreous hemorrhages and the sclerotomy was well closed. The anterior chamber hemorrhage and subconjunctival hemorrhage were completely absorbed within 14 days \[[Fig. 1D](#F0001){ref-type="fig"}\] and the IOP maintained was 14 mmHg. Six months after the surgery, BCVA was 20/40 and fundus examination revealed a flat retina. ![Sequential intraoperative photographs (A--C). (A) Microscopic overview showing no hemorrhagic sign at the end of vitrectomy. (B) About 15 s after the removal of the cannulae, hemorrhage was found inflowing into the anterior chamber from the inferotemporal area of the limbus. (C) Anterior chamber hemorrhage, severe subconjunctival hemorrhages and chemosis in the inferotemporal sclerotomy site. (D) Slit-lamp photograph at postoperative 14 days shows that the hemorrhage was completely absorbed](IJO-58-543-g001){#F0001} Case 2 {#sec2-2} ------ A 46-year-old man without diabetes was diagnosed with superior pseudophakic rhegmatogenous retinal detachment with a retinal tear at the 12 o'clock position in the right eye. BCVA was 20/100 and the axial length was 24.05 mm. Vitreous surgery was carried out using a 23-gauge vitreous cutter and the DORC two-step system. During the surgery, there were no specific events. Endolaser photocoagulation and air-gas (12% C~3~F~8~) exchange were performed. At the end of the surgery, the three microcannulae were withdrawn from the scleral tunnel and the immediate postoperative tactile IOP felt normal \[[Fig. 2A](#F0002){ref-type="fig"}\]. About 20 s after the removal of the cannulae, the anterior chamber hemorrhage was noticed \[[Fig. 2B](#F0002){ref-type="fig"}\]. It was slowly inflowing from the superonasal area of the chamber \[[Fig. 2C](#F0002){ref-type="fig"}\]. Meanwhile, there was neither subconjunctival hemorrhage nor chemosis in the superonasal sclerotomy site. Surgery was completed without any additional procedure. Postoperatively, we could not find any vitreous hemorrhages and the sclerotomy was well closed. The anterior chamber hemorrhage was completely absorbed within 7 days \[[Fig. 2D](#F0002){ref-type="fig"}\] and the IOP maintained was 17 mmHg. Six months after the surgery, BCVA was 20/40 and fundus examination revealed a flat retina. ![Sequential intraoperative photographs (A--C). (A) No hemorrhagic sign at the end of vitrectomy. (B) About 20 s after the removal of the cannulae, hemorrhage starts inflowing into the anterior chamber from the superonasal area of the limbus (yellow arrow). (C) Anterior chamber hemorrhage. (D) Slit-lamp photograph at the postoperative 7 days showing a clear anterior chamber](IJO-58-543-g002){#F0002} Discussion {#sec1-2} ========== The scleral incision with the 23-gauge or 20-gauge stiletto blade could frequently lead to bleeding from episcleral vessels or sclerotomies. Even though it is only mild bleeding, diathermy has usually been used in conventional 20-gauge vitrectomy. However, it is unavailable in transconjunctival sutureless vitrectomy. Experienced surgeons have noticed that the placement of the microcannula within the tunnel always resulted in the stoppage of the bleeding and the withdrawal of the cannula sometimes resulted in minor subconjunctival bleeding in the area of sclerotomy.\[[@CIT2]\] In a study of endoscopic observation, Koch *et al*.\[[@CIT6]\] reported sclerotomy site microbleeding, which stopped spontaneously. In this study, both patients had two-step 23-gauge sutureless vitrectomy and gas tamponade for pseudophakic rhegmatogenous retinal detachment. Intraoperatively, we could not find any intraocular or periocular hemorrhage except for minor subconjunctival bleeding in the area of sclerotomy. Soon after the removal of the microcannulae at the end of the surgery, we noticed significant subconjunctival bleeding just in one eye. Furthermore, the hemorrhage inflowing into the anterior chamber is considered as intraocular hemorrhage. Therefore, we suppose that the anterior chamber bleeding might come from the sclerotomies rather than from episcleral vessels. The posterior pressure in the gas-filled pseudophakic eye might have pushed the sclerotomy site bleeding into the anterior chamber. Although anterior chamber bleeding after sutureless vitrectomy is a rare complication, clinicians should be aware of this inevitable adverse event when preparing patients for pseudophakic rhegmatogenous retinal detachment surgery.
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The global problem of antimicrobial resistance. Along with other multidrug-resistant pathogens previously identified, Streptococcus pneumoniae is becoming a serious concern in hospital and ambulatory care settings. The AIDS pandemic has increased the threat of resistance in Mycobacterium tuberculosis. Antimicrobial drug resistance involves three molecular mechanisms drug inactivation, altered cell permeability, and alteration of target sites. Surveillance and multidisciplinary approaches will be key to containing the threat of global antimicrobial resistance.
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LISTEN: Class of 2014 Media teleconference COLORADO SPRINGS, Colo. - Karyn Bye Dietz (River Falls, Wis.), Brian Rafalski (Dearborn, Mich.), Jeff Sauer (St. Paul, Minn.) and Lou Vairo (Brooklyn, N.Y.) will be inducted into the United States Hockey Hall of Fame as the Class of 2014, it was announced today by USA Hockey. “The class of 2014 is an extraordinary collection of individuals that have had an immensely positive impact on hockey in our country,” said Ron DeGregorio, president of USA Hockey. “Cumulatively, they have been involved at every level of hockey and this group is a big reason why our sport has advanced to the point it has in the United States." Karyn Bye Dietz Karyn Bye Dietz, a pioneer in women's hockey in the United States, has had a significant impact on the sport's continued growth and evolution. She was one of the world's elite forwards during her time on the U.S. Women’s National Team from 1992-2002. During that span she represented the United States at both the 1998 and 2002 Olympic Winter Games. An alternate captain in 1998, Bye Dietz helped Team USA win the first gold medal ever awarded in women’s ice hockey at the Olympic Winter Games in Nagano, Japan. In that tournament she led the U.S. with five goals in six games, while her eight points were tied for first on the team. At the 2002 Olympic Winter Games, Bye Dietz registered three goals and six points in a silver-medal showing in Salt Lake City, Utah. She participated in six International Ice Hockey Federation Women’s World Championships (1992, ‘94, ‘97, ‘99, 2000, ‘01), receiving a silver medal at each tournament. She also skated in the 1995 and 1996 IIHF Pacific Women’s Hockey Championships, at which the U.S. placed second both years. Bye Dietz accumulated 84 points (47-37) over 51 career games in a Team USA jersey. In 1995 and 1998, she was honored as USA Hockey’s Bob Allen Women’s Player of the Year. In 2011, Bye Dietz became just the fifth woman to be inducted into the International Ice Hockey Federation Hall of Fame. A native of River Falls, Wisconsin, who currently resides in Hudson, Wisconsin, Bye Dietz played college hockey at the University of New Hampshire from 1989-93, racking up 164 points in 87 games. She was enshrined into the UNH Hall of Fame in 1998. Brian Rafalski Brian Rafalski played 15 seasons of professional hockey, including 11 in the National Hockey League. The defenseman, who grew up in the Detroit suburbs, began his NHL career in 1999-2000, helping the New Jersey Devils win the Stanley Cup and receiving NHL All-Rookie Team honors. Three years later in 2003, he hoisted the Stanley Cup yet again with the Devils. In 541 regular-season games with New Jersey, Rafalski racked up 44 goals and 311 points. He was selected to play in the 2004 and 2007 NHL All-Star Games. He spent the last four seasons of his career with the Detroit Red Wings, helping them win the Stanley Cup in 2008. He recorded 204 points (35-169) over 292 regular-season contests for the Red Wings. Overall, the 515 career points he accumulated in the NHL are 10th-best among American defensemen. Rafalski began his professional career playing from 1995-99 in Sweden and Finland. Internationally, Rafalski was a member of the U.S. Olympic Men’s Ice Hockey Team at the 2002, 2006 and 2010 Olympic Winter Games. He helped Team USA earn the silver medal at the 2002 and 2010 Olympics. At the 2010 Games in Vancouver, British Coumbia, Rafalski was named to the media all-star team and was honored as the tournament's best defenseman by the directorate after tallying four goals and eight points in six games. Across three Olympics, he tallied five goals and eight assists in 17 games. He also played for the 2004 U.S. World Cup of Hockey Team, 1995 U.S. Men’s National Team, and 1992 and 1993 U.S. National Junior Teams. During his four-year career at the University of Wisconsin, Rafalski amassed 20 goals and 98 points in 146 games. As a senior in 1994-95, he received a number of accolades, including American Hockey Coaches Association West All-America First Team, Western Collegiate Hockey Association Defensive Player of the Year and All-WCHA First Team. Rafalski spent two seasons playing junior hockey in the U.S., including one year (1990-91) with the Madison Capitols of the United States Hockey League and the other campaign (1989-90) in the North American Hockey League as a member of the Melvindale Blades. Jeff Sauer Jeff Sauer, who grew up in St. Paul, Minn., and now calls Middleton, Wis., home, has spent more than 40 years coaching hockey, and has had nothing but success in his varied endeavors. Sauer’s 31-year NCAA Division I men’s college coaching career featured 655 wins (seventh all-time) and two national championships, both of which came at the University of Wisconsin (1983, 1990). Sauer led Wisconsin to three NCAA Men's Frozen Four appearances, 12 NCAA tournament berths, six Western Collegiate Hockey Association playoff titles and two WCHA regular-season crowns in 20 seasons (1982-2002). He also spent 11 years (1971-82) as head coach of the men's ice hockey team at his alma mater, Colorado College, where he was twice named WCHA Coach of the Year (1972, 1975). Throughout his college career, he served as head coach for multiple U.S. squads, including the 1995 U.S. Men’s National Team and U.S. teams that participated in the 1990 Goodwill Games, 1989 Pravada Cup and 1997 Tampere Cup. The 2014-15 season is Sauer’s fourth campaign as head coach of the U.S. National Sled Hockey Team. He led the U.S. to the gold medal at the 2012 International Paralympic Committee Ice Sledge Hockey World Championship. Two years later, he was at the helm of the gold-medal winning 2014 U.S. Paralympic Sled Hockey Team in Sochi, Russia. Additionally, Sauer is president of the American Hearing Impaired Hockey Association. He helped select the last five U.S. Deaflympic Ice Hockey Teams, while leading the team as head coach in the last three Winter Deaflympics, including a gold medal at the 2007 Deaflympics in Salt Lake City, Utah. Sauer has been honored with USA Hockey’s Distinguished Achievement Award (2000), the American Hockey Coaches Association’s John “Snooks” Kelly Founders Award (2004) and the NHL’s Lester Patrick Trophy (2011). He has also been inducted into the Wisconsin Hockey Hall of Fame, Wisconsin Athletic Hall of Fame, the Colorado Springs Sports Hall of Fame and the Colorado College Athletic Hall of Fame. Lou Vairo Lou Vairo, who has coached players at every level in the game, has been instrumental in the development of hockey in the United States for parts of the past six decades. In the 1960s, he was a leader in building grassroots programs in New York City. During the 1970s he transitioned to coaching, highlighted by a 1976 national championship while directing the Austin (Minn.) Mavericks of the United States Hockey League. Vairo’s coaching career expanded to USA Hockey in 1979. He served as head coach of the U.S. National Junior Team from 1979-82 and once again in 2003. On five occasions (1983, 2000-03), he was head coach of the U.S. Men’s National Team. After contributing as a scout to the gold medal-winning 1980 U.S. Olympic Men’s Ice Hockey Team, he served as head coach of the 1984 U.S. Olympic Men’s Ice Hockey Team and was an assistant coach for the 2002 U.S. Olympic Men’s Ice Hockey Team that received the silver medal in Salt Lake City, Utah. From 1984-86, Vairo moved to the National Hockey League and was an assistant coach for the New Jersey Devils. He then spent the next six seasons coaching in Holland and Italy, including stints working with both countries national teams. Vairo, USA Hockey’s director of special projects since 1992, was the driving voice in the formation of the Diversity Task Force that began in 1992 to help introduce hockey to inner city and minority children. He was at the forefront of helping develop many of USA Hockey’s most successful programs, including in coaching education and player development. Vairo was at the forefront of introducing European concepts of training and playing to the United States in 1972, including methods he learned when studying with legendary Soviet coach Anatoly Tarasov. A long-time member of the IIHF Coaching Committee, Vairo concepted the current IIHF Development Camp that brings together players, coaches, and support staff from all IIHF members each summer in both Europe and Asia to foster the continued growth of the game. He was honored twice in 1994 for his lifetime commitment to hockey, receiving both the John “Snooks” Kelley Founders Award from the American Hockey Coaches Association, and the Walter Yaciuk Award from USA Hockey’s Coaching Education Program. Vairo received the NHL's Lester Patrick Trophy in 2000 and in 2010 was named the recipient of the International Ice Hockey Federation’s Paul Loicq Award. In May of 2014, he was inducted into the New York State Hockey Hall of Fame. The Class of 2014 will be formally enshrined on Dec. 4 in Minneapolis/St. Paul. More details on the induction celebration will be released over the next several weeks at USHockeyHallofFame.com. U.S. Hockey Hall of Fame inductees are chosen on the basis of extraordinary contribution to the sport of hockey in the United States. NOTES: The U.S. Hockey Hall of Fame was incorporated in 1969 and inducted its first class in 1973. To date, there are 161 enshrined members in the Hall. For information on the members of the U.S. Hockey Hall of Fame, visit USHockeyHallofFame.com ... The U.S. Hockey Hall of Fame Museum, located in Eveleth, Minn., is open daily. For hours of operation and admission prices, visit USHockeyHallMuseum.com or call 800-443-7825. COLORADO SPRINGS, Colo. - Karyn Bye Dietz (River Falls, Wis.), Brian Rafalski (Dearborn, Mich.), Jeff Sauer (St. Paul, Minn.) and Lou Vairo (Brooklyn, N.Y.) will be inducted into the United States Hockey Hall of Fame as the Class of 2014, it was announced today by USA Hockey. “The class of 2014 is an extraordinary collection of individuals that have had an immensely positive impact on hockey in our country,” said Ron DeGregorio, president of USA Hockey. “Cumulatively, they have been involved at every level of hockey and this group is a big reason why our sport has advanced to the point it has in the United States." LISTEN: Class of 2014 Media teleconference Karen Bye Dietz Karyn Bye Dietz, a pioneer in women's hockey in the United States, has had a significant impact on the sport's continued growth and evolution. She was one of the world's elite forwards during her time on the U.S. Women’s National Team from 1992-2002. During that span she represented the United States at both the 1998 and 2002 Olympic Winter Games. An alternate captain in 1998, Bye Dietz helped Team USA win the first gold medal ever awarded in women’s ice hockey at the Olympic Winter Games in Nagano, Japan. In that tournament she led the U.S. with five goals in six games, while her eight points were tied for first on the team. At the 2002 Olympic Winter Games, Bye Dietz registered three goals and six points in a silver-medal showing in Salt Lake City, Utah. She participated in six International Ice Hockey Federation Women’s World Championships (1992, ‘94, ‘97, ‘99, 2000, ‘01), receiving a silver medal at each tournament. She also skated in the 1995 and 1996 IIHF Pacific Women’s Hockey Championships, at which the U.S. placed second both years. Bye Dietz accumulated 84 points (47-37) over 51 career games in a Team USA jersey. In 1995 and 1998, she was honored as USA Hockey’s Bob Allen Women’s Player of the Year. In 2011, Bye Dietz became just the fifth woman to be inducted into the International Ice Hockey Federation Hall of Fame. A native of River Falls, Wisconsin, who currently resides in Hudson, Wisconsin, Bye Dietz played college hockey at the University of New Hampshire from 1989-93, racking up 164 points in 87 games. She was enshrined into the UNH Hall of Fame in 1998. Brian Rafalski Brian Rafalski played 15 seasons of professional hockey, including 11 in the National Hockey League. The defenseman, who grew up in the Detroit suburbs, began his NHL career in 1999-2000, helping the New Jersey Devils win the Stanley Cup and receiving NHL All-Rookie Team honors. Three years later in 2003, he hoisted the Stanley Cup yet again with the Devils. In 541 regular-season games with New Jersey, Rafalski racked up 44 goals and 311 points. He was selected to play in the 2004 and 2007 NHL All-Star Games. He spent the last four seasons of his career with the Detroit Red Wings, helping them win the Stanley Cup in 2008. He recorded 204 points (35-169) over 292 regular-season contests for the Red Wings. Overall, the 515 career points he accumulated in the NHL are 10th-best among American defensemen. Rafalski began his professional career playing from 1995-99 in Sweden and Finland. Internationally, Rafalski was a member of the U.S. Olympic Men’s Ice Hockey Team at the 2002, 2006 and 2010 Olympic Winter Games. He helped Team USA earn the silver medal at the 2002 and 2010 Olympics. At the 2010 Games in Vancouver, British Coumbia, Rafalski was named to the media all-star team and was honored as the tournament's best defenseman by the directorate after tallying four goals and eight points in six games. Across three Olympics, he tallied five goals and eight assists in 17 games. He also played for the 2004 U.S. World Cup of Hockey Team, 1995 U.S. Men’s National Team, and 1992 and 1993 U.S. National Junior Teams. During his four-year career at the University of Wisconsin, Rafalski amassed 20 goals and 98 points in 146 games. As a senior in 1994-95, he received a number of accolades, including American Hockey Coaches Association West All-America First Team, Western Collegiate Hockey Association Defensive Player of the Year and All-WCHA First Team. Rafalski spent two seasons playing junior hockey in the U.S., including one year (1990-91) with the Madison Capitols of the United States Hockey League and the other campaign (1989-90) in the North American Hockey League as a member of the Melvindale Blades. Jeff Sauer Jeff Sauer, who grew up in St. Paul, Minn., and now calls Middleton, Wis., home, has spent more than 40 years coaching hockey, and has had nothing but success in his varied endeavors. Sauer’s 31-year NCAA Division I men’s college coaching career featured 655 wins (seventh all-time) and two national championships, both of which came at the University of Wisconsin (1983, 1990). Sauer led Wisconsin to three NCAA Men's Frozen Four appearances, 12 NCAA tournament berths, six Western Collegiate Hockey Association playoff titles and two WCHA regular-season crowns in 20 seasons (1982-2002). He also spent 11 years (1971-82) as head coach of the men's ice hockey team at his alma mater, Colorado College, where he was twice named WCHA Coach of the Year (1972, 1975). Throughout his college career, he served as head coach for multiple U.S. squads, including the 1995 U.S. Men’s National Team and U.S. teams that participated in the 1990 Goodwill Games, 1989 Pravada Cup and 1997 Tampere Cup. The 2014-15 season is Sauer’s fourth campaign as head coach of the U.S. National Sled Hockey Team. He led the U.S. to the gold medal at the 2012 International Paralympic Committee Ice Sledge Hockey World Championship. Two years later, he was at the helm of the gold-medal winning 2014 U.S. Paralympic Sled Hockey Team in Sochi, Russia. Additionally, Sauer is president of the American Hearing Impaired Hockey Association. He helped select the last five U.S. Deaflympic Ice Hockey Teams, while leading the team as head coach in the last three Winter Deaflympics, including a gold medal at the 2007 Deaflympics in Salt Lake City, Utah. Sauer has been honored with USA Hockey’s Distinguished Achievement Award (2000), the American Hockey Coaches Association’s John “Snooks” Kelly Founders Award (2004) and the NHL’s Lester Patrick Trophy (2011). He has also been inducted into the Wisconsin Hockey Hall of Fame, Wisconsin Athletic Hall of Fame, the Colorado Springs Sports Hall of Fame and the Colorado College Athletic Hall of Fame. Lou Vairo Lou Vairo, who has coached players at every level in the game, has been instrumental in the development of hockey in the United States for parts of the past six decades. In the 1960s, he was a leader in building grassroots programs in New York City. During the 1970s he transitioned to coaching, highlighted by a 1976 national championship while directing the Austin (Minn.) Mavericks of the United States Hockey League. Vairo’s coaching career expanded to USA Hockey in 1979. He served as head coach of the U.S. National Junior Team from 1979-82 and once again in 2003. On five occasions (1983, 2000-03), he was head coach of the U.S. Men’s National Team. After contributing as a scout to the gold medal-winning 1980 U.S. Olympic Men’s Ice Hockey Team, he served as head coach of the 1984 U.S. Olympic Men’s Ice Hockey Team and was an assistant coach for the 2002 U.S. Olympic Men’s Ice Hockey Team that received the silver medal in Salt Lake City, Utah. From 1984-86, Vairo moved to the National Hockey League and was an assistant coach for the New Jersey Devils. He then spent the next six seasons coaching in Holland and Italy, including stints working with both countries national teams. Vairo, USA Hockey’s director of special projects since 1992, was the driving voice in the formation of the Diversity Task Force that began in 1992 to help introduce hockey to inner city and minority children. He was at the forefront of helping develop many of USA Hockey’s most successful programs, including in coaching education and player development. Vairo introduced the United States to European concepts of training and playing in 1972, including methods he learned when studying with legendary Soviet coach Anatoly Tarasov. A long-time member of the IIHF Coaching Committee, Vairo concepted the current IIHF Development Camp that brings together players, coaches, and support staff from all IIHF members each summer in both Europe and Asia to foster the continued growth of the game. He was honored twice in 1994 for his lifetime commitment to hockey, receiving both the John “Snooks” Kelley Founders Award from the American Hockey Coaches Association, and the Walter Yaciuk Award from USA Hockey’s Coaching Education Program. Vairo received the NHL's Lester Patrick Trophy in 2000 and in 2010 was named the recipient of the International Ice Hockey Federation’s Paul Loicq Award. In May of 2014, he was inducted into the New York State Hockey Hall of Fame. The Class of 2014 will be formally enshrined on Dec. 4 in Minneapolis/St. Paul. More details on the induction celebration will be released over the next several weeks at USHockeyHallofFame.com. U.S. Hockey Hall of Fame inductees are chosen on the basis of extraordinary contribution to the sport of hockey in the United States. NOTES: The U.S. Hockey Hall of Fame was incorporated in 1969 and inducted its first class in 1973. To date, there are 161 enshrined members in the Hall. For information on the members of the U.S. Hockey Hall of Fame, visit USHockeyHallofFame.com ... The U.S. Hockey Hall of Fame Museum, located in Eveleth, Minn., is open daily. For hours of operation and admission prices, visit USHockeyHallMuseum.com or call 800-443-7825.
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Glucose tolerance status and 20 year cancer incidence. Type 2 diabetes, an extreme state of glucose intolerance, has been found to be associated with cancer mortality; less is known about impaired glucose tolerance and cancer incidence. To examine the association between fasting and post-load plasma glucose and insulin, and the 20 year incidence of cancer. We followed a sample of the Jewish Israeli population (n = 2780), free of cancer at baseline, from 1977-1980 to 1999 for cancer incidence and mortality. Baseline fasting and 1 and 2 hour post-load plasma glucose levels were recorded, as was insulin, in 1797 of them. During 20 years, 329 individuals (11.8%) developed cancer. Cancer incidence for all sites differed between men and women (13.0% and 10.7%, P = 0.03), and among different glucose tolerance status groups (P = 0.01). Cancer incidence hazard ratio, by glucose status adjusted for gender, age, ethnicity, smoking and body mass index, was 1.24 (95% CI 0.96-1.62, P = 0.10) for impaired fasting glucose or impaired glucose tolerance, and 1.32 (95% CI 0.96-1.81, P = 0.09) for type 2 diabetes mellitus, compared with those who were normoglycemic at baseline. Fasting insulin and cancer incidence were not associated. An increased long-term cancer risk for individuals with impaired fasting glucose or glucose tolerance, or diabetes, is suggested. Even this modest association could have substantial public health consequences.
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# Copyright 2018 DeepMind Technologies Limited. # # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, software # distributed under the License is distributed on an "AS IS" BASIS, # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. # See the License for the specific language governing permissions and # limitations under the License. """Combinatorics utility functions.""" from __future__ import absolute_import from __future__ import division from __future__ import print_function import math import random # Dependency imports from six.moves import range from six.moves import zip def uniform_positive_integers_with_sum(count, sum_): """Returns list of size `count` of integers >= 1, summing to `sum_`.""" assert sum_ >= 0 if count > sum_: raise ValueError('Cannot find {} numbers >= 1 with sum {}' .format(count, sum_)) if count == 0: return [] # Select `count - 1` numbers from {1, ..., sum_ - 1} separators = random.sample(list(range(1, sum_)), count - 1) separators = sorted(separators) return [right - left for left, right in zip([0] + separators, separators + [sum_])] def uniform_non_negative_integers_with_sum(count, sum_): """Returns list of size `count` of integers >= 0, summing to `sum_`.""" positive = uniform_positive_integers_with_sum(count, sum_ + count) return [i - 1 for i in positive] def log_number_binary_trees(size): """Returns (nat) log of number of binary trees with `size` internal nodes.""" # This is equal to log of C_size, where C_n is the nth Catalan number. assert isinstance(size, int) assert size >= 0 log = 0.0 for k in range(2, size + 1): log += math.log(size + k) - math.log(k) return log
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Comment Wall (3 comments) You need to be a member of CoreDJRadio to add comments! whats good i go by the name of Los Haas coming through to show you some love to your page check me ou imt somethin fresh you should definlety hit up my page and listen to some of my songs.20 ten lets get it in! follow me on twitter http://www.twitter.com/loshaas Please Share with a friend and feel free to add it to your profile. I could really use your support to get THIS POSITIVE VIBE TO THE WORLD. Here are a couple of videos from the album as well to check out. God Bless! PEEP THE VIDEOS BELOW FOR SOME SAMPLES OF MY NEW ALBUM
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Q: How to create Particles structure from text in AS3? I want to take any Text sting and form from it text formed by particles in actionscript 3 (In flash \ flex) I see I need some lib for this. but all libs Ive seen do not have such functionalyty by default... So I want to get something like this So Is there any sych lib? or way of doing it with some lib? It should be Free and Opensource (any license like GPL, LGPL etc will be ok). A: There's a method for doing this described here: http://blog.soulwire.co.uk/laboratory/flash/as3-alphabet-particles There are some other ready-made components here: http://www.flashcomponents.net/component/advanced_text_particles.html http://www.blogaboutflash.com/2008/08/using-particles-to-fill-dynamic-content.html ... but they might be less useful to you than the first link. Hope this helps.
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// ***************************************************************************** // // Filename : MouseSystem.h // // Purpose : Defines and typedefs for the "mousesystem" mouse region handler // // Modification history : // // 30jan97:Bret -> Creation // // ***************************************************************************** #ifndef _MOUSE_SYSTEM_H_ #define _MOUSE_SYSTEM_H_ #include "JA2Types.h" #include "Types.h" #include <string_theory/string> #define _JA2_RENDER_DIRTY // Undef this if not using the JA2 Dirty Rectangle System. // Mouse Region Flags #define MSYS_NO_FLAGS 0x00000000 #define MSYS_MOUSE_IN_AREA 0x00000001 #define MSYS_REGION_EXISTS 0x00000010 #define MSYS_REGION_ENABLED 0x00000040 #define MSYS_FASTHELP 0x00000080 #define MSYS_GOT_BACKGROUND 0x00000100 #define MSYS_HAS_BACKRECT 0x00000200 #define MSYS_FASTHELP_RESET 0x00000400 #define MSYS_ALLOW_DISABLED_FASTHELP 0x00000800 struct MOUSE_REGION; typedef void (*MOUSE_CALLBACK)(MOUSE_REGION*, INT32); struct MOUSE_REGION { void ChangeCursor(UINT16 crsr); void Enable() { uiFlags |= MSYS_REGION_ENABLED; } void Disable() { uiFlags &= ~MSYS_REGION_ENABLED; } void SetFastHelpText(const ST::string& str); void AllowDisabledRegionFastHelp(bool allow); void SetUserPtr(void* ptr) { user.ptr = ptr; } template<typename T> T* GetUserPtr() const { return static_cast<T*>(user.ptr); } INT16 X() const { return RegionTopLeftX; } INT16 Y() const { return RegionTopLeftY; } INT16 W() const { return RegionBottomRightX - RegionTopLeftX; } INT16 H() const { return RegionBottomRightY - RegionTopLeftY; } INT8 PriorityLevel; // Region's Priority, set by system and/or caller UINT32 uiFlags; // Region's state flags INT16 RegionTopLeftX; // Screen area affected by this region (absolute coordinates) INT16 RegionTopLeftY; INT16 RegionBottomRightX; INT16 RegionBottomRightY; INT16 MouseXPos; // Mouse's Coordinates in absolute screen coordinates INT16 MouseYPos; INT16 RelativeXPos; // Mouse's Coordinates relative to the Top-Left corner of the region INT16 RelativeYPos; UINT16 ButtonState; // Current state of the mouse buttons UINT16 Cursor; // Cursor to use when mouse in this region (see flags) MOUSE_CALLBACK MovementCallback; // Pointer to callback function if movement occured in this region MOUSE_CALLBACK ButtonCallback; // Pointer to callback function if button action occured in this region union // User Data, can be set to anything! { INT32 data[4]; void* ptr; } user; //Fast help vars. INT16 FastHelpTimer; // Countdown timer for FastHelp text ST::utf32_buffer FastHelpText; // Text string for the FastHelp (describes buttons if left there a while) BACKGROUND_SAVE* FastHelpRect; MOUSE_REGION* next; // List maintenance, do NOT touch these entries MOUSE_REGION* prev; }; // Mouse region priorities #define MSYS_PRIORITY_LOWEST 0 #define MSYS_PRIORITY_LOW 15 #define MSYS_PRIORITY_NORMAL 31 #define MSYS_PRIORITY_HIGH 63 #define MSYS_PRIORITY_HIGHEST 127 // Mouse system defines used during updates #define MSYS_NO_ACTION 0 #define MSYS_DO_MOVE 1 #define MSYS_DO_LBUTTON_DWN 2 #define MSYS_DO_LBUTTON_UP 4 #define MSYS_DO_RBUTTON_DWN 8 #define MSYS_DO_RBUTTON_UP 16 #define MSYS_DO_LBUTTON_REPEAT 32 #define MSYS_DO_RBUTTON_REPEAT 64 #define MSYS_DO_WHEEL_UP 0x0080 #define MSYS_DO_WHEEL_DOWN 0x0100 #define MSYS_DO_MBUTTON_DWN 0x0200 #define MSYS_DO_MBUTTON_UP 0x0400 #define MSYS_DO_MBUTTON_REPEAT 0x0800 #define MSYS_DO_BUTTONS (MSYS_DO_LBUTTON_DWN | MSYS_DO_LBUTTON_UP | MSYS_DO_RBUTTON_DWN | MSYS_DO_RBUTTON_UP | MSYS_DO_RBUTTON_REPEAT | MSYS_DO_LBUTTON_REPEAT | MSYS_DO_WHEEL_UP | MSYS_DO_WHEEL_DOWN | MSYS_DO_MBUTTON_DWN | MSYS_DO_MBUTTON_UP | MSYS_DO_MBUTTON_REPEAT) // Mouse system button masks #define MSYS_LEFT_BUTTON 1 #define MSYS_RIGHT_BUTTON 2 #define MSYS_MIDDLE_BUTTON 0x04 // Mouse system special values #define MSYS_NO_CALLBACK NULL #define MSYS_NO_CURSOR 65534 // Mouse system callback reasons #define MSYS_CALLBACK_REASON_NONE 0 #define MSYS_CALLBACK_REASON_MOVE 2 #define MSYS_CALLBACK_REASON_LBUTTON_DWN 4 #define MSYS_CALLBACK_REASON_LBUTTON_UP 8 #define MSYS_CALLBACK_REASON_RBUTTON_DWN 16 #define MSYS_CALLBACK_REASON_RBUTTON_UP 32 #define MSYS_CALLBACK_REASON_BUTTONS (MSYS_CALLBACK_REASON_LBUTTON_DWN|MSYS_CALLBACK_REASON_LBUTTON_UP|MSYS_CALLBACK_REASON_RBUTTON_DWN|MSYS_CALLBACK_REASON_RBUTTON_UP|MSYS_CALLBACK_REASON_MBUTTON_DWN|MSYS_CALLBACK_REASON_MBUTTON_UP) #define MSYS_CALLBACK_REASON_LOST_MOUSE 64 #define MSYS_CALLBACK_REASON_GAIN_MOUSE 128 #define MSYS_CALLBACK_REASON_LBUTTON_REPEAT 256 #define MSYS_CALLBACK_REASON_RBUTTON_REPEAT 512 #define MSYS_CALLBACK_REASON_MBUTTON_DWN 0x2000 #define MSYS_CALLBACK_REASON_MBUTTON_UP 0x4000 #define MSYS_CALLBACK_REASON_MBUTTON_REPEAT 0x8000 //Kris: Nov 31, 1999 //Added support for double clicks. The DOUBLECLICK event is passed combined with //the LBUTTON_DWN event if two LBUTTON_DWN events are detected on the same button/region //within the delay defined by MSYS_DOUBLECLICK_DELAY (in milliseconds). If your button/region //supports double clicks and single clicks, make sure the DOUBLECLICK event is checked first (rejecting //the LBUTTON_DWN event if detected) #define MSYS_CALLBACK_REASON_LBUTTON_DOUBLECLICK 1024 #define MSYS_CALLBACK_REASON_WHEEL_UP 0x0800 #define MSYS_CALLBACK_REASON_WHEEL_DOWN 0x1000 // Internal Functions void MSYS_SetCurrentCursor(UINT16 Cursor); // External void MSYS_Init(void); void MSYS_Shutdown(void); void MSYS_DefineRegion(MOUSE_REGION *region,UINT16 tlx,UINT16 tly,UINT16 brx,UINT16 bry,INT8 priority, UINT16 crsr,MOUSE_CALLBACK movecallback,MOUSE_CALLBACK buttoncallback); void MSYS_RemoveRegion(MOUSE_REGION *region); /* Set one of the user data entries in a mouse region */ void MSYS_SetRegionUserData(MOUSE_REGION*, UINT32 index, INT32 userdata); /* Retrieve one of the user data entries in a mouse region */ INT32 MSYS_GetRegionUserData(MOUSE_REGION const*, UINT32 index); // This function will force a re-evaluation of mous regions // Usually used to force change of mouse cursor if panels switch, etc void RefreshMouseRegions(void); // Now also used by Wizardry -- DB void RenderFastHelp(void); // Hook to the SGP's mouse handler void MouseSystemHook(UINT16 Type, UINT16 Xcoord, UINT16 Ycoord); class MouseRegion : private MOUSE_REGION { public: MouseRegion(UINT16 const x, UINT16 const y, UINT16 const w, UINT16 const h, INT8 const priority, UINT16 const cursor, MOUSE_CALLBACK const movecallback, MOUSE_CALLBACK const buttoncallback) { MOUSE_REGION* const r = this; *r = MOUSE_REGION{}; MSYS_DefineRegion(r, x, y, x + w, y + h, priority, cursor, movecallback, buttoncallback); } ~MouseRegion() { MSYS_RemoveRegion(this); } MOUSE_REGION const& Base() const { return *this; } // XXX hack using MOUSE_REGION::ChangeCursor; using MOUSE_REGION::Disable; using MOUSE_REGION::Enable; using MOUSE_REGION::MouseXPos; using MOUSE_REGION::MouseYPos; using MOUSE_REGION::PriorityLevel; using MOUSE_REGION::RegionBottomRightX; using MOUSE_REGION::RegionBottomRightY; using MOUSE_REGION::RegionTopLeftX; using MOUSE_REGION::RegionTopLeftY; using MOUSE_REGION::RelativeXPos; using MOUSE_REGION::RelativeYPos; using MOUSE_REGION::SetFastHelpText; using MOUSE_REGION::SetUserPtr; using MOUSE_REGION::uiFlags; }; #endif
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<?xml version="1.0" encoding="utf-8"?> <LinearLayout xmlns:android="http://schemas.android.com/apk/res/android" android:layout_width="fill_parent" android:layout_height="fill_parent" android:gravity="center_vertical" android:paddingBottom="4.0dip" android:paddingLeft="4.0dip" android:paddingRight="4.0dip" android:paddingTop="4.0dip" > <ImageView android:id="@+id/notification_icon" android:layout_width="50.0dip" android:layout_height="50.0dip" android:src="@drawable/ic_launcher" android:scaleType="centerInside" /> <LinearLayout android:id="@+id/general_notice" android:layout_width="fill_parent" android:layout_height="fill_parent" android:layout_marginLeft="12.0dip" android:gravity="center_vertical" android:orientation="vertical" > <TextView android:id="@+id/notification_title" android:layout_width="wrap_content" android:layout_height="wrap_content" android:ellipsize="marquee" android:fadingEdge="horizontal" android:gravity="center_vertical" android:paddingLeft="4.0dip" android:text="way" android:textAppearance="@style/TextAppearance.StatusBar.EventContent.Title" /> <TextView android:id="@+id/notification_content" android:layout_width="wrap_content" android:layout_height="wrap_content" android:ellipsize="marquee" android:fadingEdge="horizontal" android:gravity="center_vertical" android:paddingLeft="4.0dip" android:text="new message" android:singleLine="true" android:textAppearance="@style/TextAppearance.StatusBar.EventContent" /> <LinearLayout android:id="@+id/notif_pro_bar_layout" android:layout_width="fill_parent" android:layout_height="fill_parent" android:visibility="gone" > <ProgressBar android:id="@+id/notif_pro_bar" style="?android:attr/progressBarStyleHorizontal" android:layout_width="fill_parent" android:layout_height="5.0dip" android:layout_gravity="center_vertical" /> </LinearLayout> </LinearLayout> </LinearLayout>
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CiteAs.org: Discovering and Improving software requests for citation CiteAs.org links between pieces of software and their requested citations. It enables moving from the name of a piece of software, its webpage URL, or a DOI, directly to the machine-readable metadata (e.g., BibTex, Zotero auto-import) for the citation the author of the software package wants you to use. CiteAs.org is funded by the Digital Science program at the Sloan Foundation (Grant Number 8028), and conceived and developed by Heather Piwowar and Jason Priem at ImpactStory, together with James Howison from the Information School at the University of Texas at Austin. Great software work &rightarrow; Clear requests for citation &rightarrow; More visibility in publications &rightarrow; More credit &rightarrow; Better Software &rightarrow; Better Research Getting credit for useful software in science is important, yet it is rarely clear how the authors of a piece of software would like to be cited. Howison and Bullard, 2013 found that less than half of the times in which publications actually mentioned software were formal, traceable, citations. At least part of the reason is that software very rarely contains citation information, and even when software does, that information is certainly not as obvious as it is in a paper. With a paper, if you have the paper you have the metadata right there in front of you: But if you have a piece of software, you very likely don’t have the metadata needed to cite it. You know the name of the code, you might know the homepage of the project that creates it, but you don’t know how to cite it. In part this is because with software there is no standard place to “write” the information, but the problem is compounded because authors sometimes want their users to cite something other than the piece of software directly. Examples include citing a paper that introduces the software (or demonstrated its potential), a published software manual or book, a “software paper” created specifically as a citation target, or a benchmarking paper. Great work is being done to guide best practices (including the FORCE11 Working Group on Software Citation) which recommends always including a direct citation to the software itself, including version numbers—something key for reproducibility—in addition to papers. We don’t disagree, but we think it’s important to let the authors decide how their contribution should be acknowledged and to link users with those requests. One approach to making this link is to create a new standard format and location to make clear requests, such as including a free text request in a CITATION file or a machine readable set of requests in a CodeMeta file or CITATION.cff file file. These have the advantage of being easy to locate and read, but the disadvantage of requiring everyone to adopt a new practice before this approach can work. We know that people already make requests for citation in a whole range of places, including requests on project web-pages that provide bibtex or DOIs, metadata associated with DOIs or repositories (such as Github and Gitlab), and in language specific formats (such as R’s citation() method, which reads from a DESCRIPTION file). CiteAs includes a web-scraper that seeks out requests wherever they might be, following a set of logical rules based on how we’ve seen people ask for a citation. We ask users to start with something they know about the software, such as the project name, a project “landing page” (e.g., SciPy’s requests for citations), or a project’s repository URL. We then have plugins arranged in a sequence that obtain data from out on the web and seek the best citation request, prioritizing metadata by its imputed intentionality, such as CITATION.cff file, CITATION file, citation() calls, DOAP metadata, and metadata registered associated with a DOI (e.g., Zenodo’s software DOIs). Of medium priority is metadata discovered through natural language requests on webpages (such as bibtex or other formats on landing pages). Finally we fall back to creating a simple citation to a repository or even web-page. We want to discover and honor author’s requests and simultaneously educate authors about how to make clearer or more specific citation requests, encouraging them to make use of more expressive formats. We do that by showing our discovery process and highlighting missing, higher intentionality, opportunities to make requests. Examples Example 1: YT YT is a python package for analyzing and visualizing volumetric data. Entering the YT webpage URL into the CiteAs.org search field retrieves the correct citation in a variety of different common citation formats as well as in structured data that can be imported into Zotero in one click: Since a key goal of CiteAs is education, the process used to find this citation is also highlighted on the results page: From this list we can see the steps the application took to find the citation—which both helps establish provenance and also educate users about better ways to register and discover software citation metadata. Example 2: Stringr The Stringr package provides wrappers for common string operations in R. Given the URL for the package’s CRAN page, CiteAs finds and displays the correct citation for this package. CiteAs takes quite a few hops to finally figure out where the canonical citation metadata is, but it does eventually find it in the R DESCRIPTION file. Again, the display of all these steps helps users understand more about the possible approaches to software citation. The icon next to each step links users to additional documentation. Challenges and next steps Locating requests Eventually we plan to incorporate an additional source: the manner in which packages are already being mentioned in publications. We plan to obtain this through machine learning of the literature (“entity recognition” for software). Towards this, we have trained content analytic coders labeling a randomly chosen set of publications and are making the labelled dataset available at Softcite Dataset. Using that system we plan to add “Here’s your current request and here’s how we see your software mentioned in the literature. If you’d like to change those practices you could start with a clear, standardized, machine-readable request.” Presenting information We have encountered plenty of challenges in designing the output of CiteAs to simultaneously realize our practical goals and our goal of educating users on clearer ways to make citations. We are still working towards better visualizations of the search process and ways of dealing with finding multiple different requests. We considered allowing users to “claim” their project and then to mark their preferred citation, but we want to improve existing infrastructure, rather than become centralized infrastructure ourselves. The system will therefore make recommendations about how to write clearer requests that everyone can read, rather than host those requests onsite. Sustainability CiteAs faces a key challenges that any grant-funded piece of software faces: how to continue after the end of the grant. Handling “bit rot” (or “software collapse”) will be a challenge, but in addition any web-hosted service has on-going financial needs for server space. Our by-no-means-perfect approach is to demonstrate the feasibility of the approach and seek partners to whom to pass off the service. Please try CiteAs and report issues We would love to hear your experiences with the CiteAs.org service. We are especially interested in hearing about requests that CiteAs is not currently finding, as well as feedback on the presentation of the results, and the position of CiteAs within the ecosystem of related services. We are also very interested in efforts within software ecosystems or fields to provide requests for citation that we could collect. Report issues or opportunities on our GitHub issues page. Great software work &rightarrow; Clear requests for citation &rightarrow; More visibility in publications &rightarrow; More credit &rightarrow; Better Software &rightarrow; Better Research
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The present invention relates to methods of controlling the particle size of titanium dioxide produced by oxidizing a titanium halide in the vapor phase. The production of rutile titanium dioxide by reacting a gaseous titanium halide such as titanium tetrachloride with oxygen (often referred to as the “chloride process”) is well known. Heated streams of gaseous titanium halide and oxygen (or an oxygen-containing gas) are combined at high flow rates in a reaction zone of a tubular vapor phase oxidation reactor. Aluminum chloride, typically generated on-site, is often added to the titanium halide stream to promote rutilization of the titanium dioxide. A high temperature oxidation reaction takes place whereby particulate solid titanium dioxide and gaseous reaction products are produced. The titanium dioxide and gaseous reaction products are cooled, and the titanium dioxide particles are recovered. The solid titanium dioxide is very useful as a pigment. The pressure at which the oxidation reaction is carried out can vary from atmospheric pressure to about 50 psig. It is often desirable to carry out the reaction at a relatively high pressure, i.e., at a pressure that is at least about 15 psig. For example, at a pressure above about 30 psig, the need to recompress recycle chlorine gas is eliminated. The mean particle size of the resulting titanium dioxide can be important, for example, when the titanium dioxide is to be used as a pigment. The particle size has a direct impact on the optical properties of the pigment. Certain plastics grade pigments require a relatively low particle size. Unfortunately, the particle size of the titanium dioxide can be difficult to control, particularly when the oxidation reaction is carried out at a relatively high pressure. As the reaction pressure increases, the mean particle size of the titanium dioxide tends to increase as well. The increased pressure increases the density of the particles in the vapor phase in the reactor, which leads to a higher number of particle collisions. The higher number of particle collisions results in coalescence and growth of the particles. It is known that the particle size of the titanium dioxide in a vapor phase oxidation reactor can be controlled by adding ionizing metals to the reactor. U.S. Pat. No. 3,208,866, assigned to E.I. du Pont de Nemours and Company, teaches that the particle size of the titanium dioxide can be controlled by introducing a metal ion nucleant to the reactor. The metal ion nucleant can be charged to the oxidation reactor either in its elemental state (as a vapor, liquid or solid) or in the form of various inorganic and organic compounds containing the metal. The nucleant is preferably introduced into the reactor by adding it to the oxygen or oxygen-containing gas stream being charged to the reactor. The nucleant prevents the particles from colliding and coalescing. In accordance with U.S. Pat. No. 5,204,083, assigned to Kerr-McGee Chemical Company LLC, a metal ion-containing compound is introduced into the reaction zone of the oxidation reactor in at least two separate and discrete increments. The first increment is introduced into the reaction zone at a point therein prior to the onset of the reaction between the titanium halide and the oxidizing gas within the reaction zone. A second increment is introduced into the reaction zone at a point therein subsequent to the reaction of at least about 20 weight percent of the titanium halide and the oxidizing gas. The addition of the metal ion-containing compound in separate and discrete increments allows for improved particle size control and avoids certain processing problems associated with the use of metal ion-containing compounds. U.S. Pat. No. 5,536,487, assigned to Kronos, Inc., describes a process for manufacturing titanium dioxide by the chloride process wherein the metal used to make aluminum trichloride and a particle control additive are introduced by way of two separately-controllable addition branches (a main branch and a subsidiary branch) into the aluminum chloride generator. The particle control additive, an alkali metal salt, is introduced by way of the subsidiary branch in a controlled addition provided by a “dilution” mixture of the salt in aluminum powder. Additional agents are included which improve the free-flowing properties of the mixture. While the approaches used heretofore for controlling the particle size of the titanium dioxide have been effective, they are limited in certain respects. For example, it can be labor intensive to mix the alkali metal salt, powdered aluminum, and additional agents in accordance with U.S. Pat. No. 5,536,487. Powdered aluminum is pyrophoric and thus hazardous, and the use of multiple mixing devices is cumbersome. Furthermore, the effectiveness of any ionizing agent can be diminished when the pressure at which the oxidization reaction is carried out is increased. It becomes difficult at high operating pressures to achieve titanium dioxide pigment particle sizes suitable for plastics applications. At such pressures, different mechanisms are needed in order to achieve effective particle size control.
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Transitions 2017-2-84 minutes to readContributors In this article CSS transitions enable you to change CSS property values over a specified duration of time, animating the property changes, rather than having them occur immediately. CSS3 Transitions are defined by the World Wide Web Consortium (W3C) in the CSS Transitions Module Level 3 specification. CSS Transitions are now supported for use on SVG elements in Microsoft Edge. The transition-property property You use the transition-property property to identify one or more CSS properties to which the transition effect(s) will be applied when a new property value is specified. The transition-property property can either be set to a comma-separated list of CSS properties or to one of the following values: none: No transition effect is applied when a new property value is specified. All transition properties are ignored. all: This is the default value. Every property that supports transitions has the transition effect applied when a new value for the property is specified. The transition-duration property The transition-duration property defines the length of time that a transition takes, specifying one or more comma-separated time values indicating the length of time for the transition from the old value to the new value. Each value is in the form of a floating-point number, followed by a time unit designator (ms or s). .example { transition-duration: 3s; } The transition-timing-function property The transition-timing-function property enables a transition to change speed over its duration by describing how the intermediate values used during a transition will be calculated. You do this by specifying one or more comma-separated animation timing functions based on a cubic bézier curve, which takes four parameters. You can either specify the curve explicitly by using the cubic-bezier function and entering the four values manually, or you can choose from several function keywords, each of which corresponds to a commonly used timing function. The possible values can be any of the following. See the transition-timing-function reference page for descriptions of each function. cubic-bezier(*x₁*,*y₁*,*x₂*,*y₂*) The four parameters of this function must be floating point values between 0 and 1, inclusive. The values correspond to the x- and y-coordinates of the P₁ and P₂ points of the cubic bézier curve. For properties other than opacity and color, the cubic-bezier curve function accepts y-coordinates outside the standard range of between 0 and 1. This enables you to create "elastic" or "bounce" transition effects. ease This is the default value. This timing function gradually increases in speed at the start, animates at full speed, and then gradually decreases in speed at the end. linear This timing function has a consistent speed from start to end. ease-in This timing function gradually increases in speed at the start. ease-out This timing function gradually decreases in speed at the end. ease-in-out This timing function gradually increases in speed at the start and then gradually decreases in speed at the end. steps This timing function defines a stepped timing function, and takes two parameters. The first parameter specifies the number of intervals; the optional second parameter specifies the point in the interval where the property value changes. The second parameter is constrained to the values start or end, which is the default. The transition-delay property The transition-delay property enables you to delay the start of a transition, or make it appear as if the transition is already in progress. If the value for the transition-delay property is a negative value, the transition will execute as soon as it is applied, but will appear to have begun execution at the specified offset, or during its play cycle. .example:hover { transition-delay: 3s; } In the example above, the user would have to hover over the element for more than 3 seconds in order to see the transition effect begin. The transition property The transition shorthand property combines the four transition properties described previously into a single property. The transition property values must be set in the following order:
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do you mean you changed it to PPT - it looks like that's what's in there already... Kerri Thompson@ENRON 03/01/2001 09:04 AM To: Kate Symes/PDX/ECT@ECT cc: Subject: ch deal 534053 to ppt
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Bestwick-led majority authorized lawsuit, police complaint and instigated citizens court action against mayor -- but all have now collapsed The City of Nanaimo has dropped its headline-grabbing lawsuit against mayor Bill McKay a year after trashing his reputation and costing taxpayers an undisclosed sum in legal fees. Dropping the civil suit is an embarrassing retreat for councillor Bill Bestwick and his council majority, who have campaigned with city manager Tracy Samra to oust the mayor since taking control of the city in late 2015. With Ms. Samra’s position under pressure due to a union-led revolt over her management, the collapse of the city’s case against the mayor is likely to deepen tensions between her and the Bestwick-led majority. ‘Vengeful politics’ The decision to call a halt to the court proceedings, which was filed on Friday, comes two months after the RCMP and a special prosecutor dismissed a related complaint the council majority authorized Ms. Samra to file against Mr. McKay. The mayor has all along maintained his innocence, slamming the actions against him as “vengeful politics.” It’s believed that he has spent more than $10,000 out of his own pocket defending himself against the city’s actions. City officials have so far refused to disclose how much taxpayers have spent on the civil suit and police complaint against the mayor. The decisions to launch the unusual legal actions were made at a secret council meeting on November 7, 2016 by councillors Bestwick, Jim Kipp, Gord Fuller, Bill Yoachim and Jerry Hong. At the time, the council majority and Ms. Samra were mired in a series of controversies just as council was debating plans to build a $100 million ice arena that was being championed by Mr. Bestwick and his council allies. The allegations had the effect of shifting media attention to the mayor and undermining his credibility as an opponent of the multiplex plan, which was ultimately defeated by 80.3% of voters in a referendum last March. Bestwick group instigated citizens’ suit At the November 2016 closed meeting, the five-man majority also approved issuing a hard-hitting news release outlining several allegations of conflict of interest involving the mayor. The release (PDF) was issued with the specific purpose of encouraging citizens to file their own lawsuit to have the mayor disqualified from office, released in-camera minutes show. On December 22, 2016, a group of 10 citizens with links to the council majority and Ms. Samra filed a sloppily worded lawsuit asking the court to disqualify the mayor from office. The citizens were Tim McGrath, Robert Fuller, Beverly Jarvis, Louise Gilfoy, Leslie Barclay, Bill McCallum, Brian Naylor, Brian Main, Terry Lee Wagar and Mary Montague. The citizens’ suit was never served on the mayor and expired last Friday. National headlines The following week, on December 28, 2016, the city filed its unusual legal action against Mr. McKay in the BC Supreme Court in Nanaimo. News of the lawsuit made headlines across the country. It was believed to be the first time in BC that a city had sued a sitting mayor for damages. The city alleged that the mayor had breached confidentiality to help 42-year veteran administrative assistant Marilyn Smith in her wrongful dismissal case against the city and Ms. Samra. Mr. McKay denied any wrongdoing in comments to the media but never formally responded to the city’s court claim because it wasn’t served on him. Censure hearing proposed In a news release today, Nanaimo city council said it had unanimously decided to file a Notice of Discontinuance at its December 18 in-camera meeting and would pursue the matter further through a censure hearing in early 2018. The statement blamed “delays in the judicial system as well as the delays to address the issues by the (mayor) and his legal team” for the lawsuit being dropped. “Council has chosen the alternative route of a censure hearing to achieve a meaningful outcome,” said the statement. However, it’s unlikely that a censure hearing will be held or that it will be able to rule on the issues. Councillors have yet to issue a ruling on a censure hearing last month related to respectful workplace complaints that Ms. Samra filed against Mr. McKay and councillor Diane Brennan. It is understood that councillors have been advised by the city’s lawyers that they are too conflicted to be able to stand in judgment of their colleagues. McKay hits back In statement, Mr. McKay said: “While the city’s news release says the justice system requires complaints be acted on within a 12 month window, that requirement at issue was simply that the city serve its notice of claim on me. I do not understand why the city was unable to do that within the 12 months it had. I am easy to find at City Hall.” The mayor also rejected the claim in the city’s news release that he and his legal team has caused delays, saying the case “never got to the stage of me being required to do anything.” Added the mayor: “I remain of the belief that the city’s proceeding against me was completely without substance, and an attempt to abuse the process of the court. “While I welcome what should be an end to the city incurring unnecessary legal fees in this matter, I regret that I will not be able to defend my name against the city’s allegations in a court of law where the process is fair, transparent and unbiased.” Mr. McKay called on council to publicly disclose the legal costs to date and what will be spent on a future censure hearing. News Nanaimo has requested comment from council members and will update this article if and when they respond.
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Q: can jquery and javascript co-exist in a file? can i use javascript and jquery both in a page? like: <script type="text/javascript"> $(document).ready(function(){ //some jquery }); function xyz(){ //javascript statements //some jquery statements } </script> A: Yes. jQuery is JavaScript. jQuery simply provides some very convenient functions that takes care of some of the pain of writing JavaScript. A: jQuery == javascript so Yes, javascript functions can co-exist with jQuery functions, just use the correct namespace for the function you want to call... A: jQuery is a Javascript library so whenever you're using it on a page, you're already using Javascript. So yes, you can.
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Jagan Mohan Reddy led his party to a resounding victory in the recent Assembly and Lok Sabha elections. Jagan Mohan Reddy, who led the YSR congress, to a thumping victory in the assembly elections, took oath as the chief minister of Andhra Pradesh. Mr Reddy took oath of office and secrecy at a grand public function at the IGMC Stadium in nearby Vijayawada, becoming the second chief minister of Andhra Pradesh after its bifurcation. Mr Reddy was administered the oath by Governor ESL Narasimhan at 12:23 pm. 46-year-old Jagan led his party to a resounding victory in the recent Assembly and Lok Sabha elections. The YSR Congress won 151 of the 175 seats in the state Assembly, decimating the TDP headed by N Chandrababu Naidu, who became the first chief minister of the state after it was bifurcated to carve out Telangana five years ago. YSRC won 22 of the 25 Lok Sabha seats. Only Mr Reddy took oath Thursday and his council of ministers is expected to be sworn in on June 7. Telangana Chief Minister K Chandrasekhar Rao, DMK chief M K Stalin and Puducherry Health Minister Malladi Krishna Rao were the special guests. Telugu Desam Party (TDP) chief N Chandrababu Naidu has turned down invitation to attend Jagan Mohan Reddy's swearing-in ceremony, news agency ANI has reported. Here are the HIGHLIGHTS of the Jagan Mohan Reddy's swearing-in ceremony: May 30, 2019 15:01 (IST) Telangana Chief Minister KC Rao attended the ceremony. "He is a young leader, he has a big responsibility, only with mutual understanding between the two Telugu states the people can be developed. Jagan should continue as the chief minister for 3-4 terms," he said. May 30, 2019 14:52 (IST) Congratulations to @ysjagan on taking oath as Andhra Pradesh's Chief Minister. I assure full cooperation from the Centre. We will work together to take Andhra Pradesh to new heights. - Narendra Modi (@narendramodi) May 30, 2019 May 30, 2019 14:48 (IST) Jagan Mohan Reddy had quit the Congress and floated YSR Congress in 2011, one-and-a-half year after his father died in a helicopter crash. May 30, 2019 14:19 (IST) Jagan Mohan Reddy will not attend Prime Minister Narendra Modi's swearing-in. May 30, 2019 14:11 (IST) Both Telugu states (Andhra Pradesh & Telangana) need to be developed with mutual understanding, Jagan Mohan Reddy said today. May 30, 2019 13:48 (IST) Best wishes to Shri YS Jagan Mohan Reddy on taking oath as the Chief Minister of Andhra Pradesh. @ysjagan - Arun Jaitley (@arunjaitley) May 30, 2019 May 30, 2019 13:33 (IST) Telangana Deputy Chief Minister Mahmood Ali, Assembly Speaker Pocharam Srinivasa Reddy, minister Talasani Srinivasa Yadav also attended the swearing-in ceremony. Mr Reddy's mother and YSRC honorary president Y S Vijayamma, his wife Bharati and sister Sharmila and other members of the family were specially seated on the dais. May 30, 2019 13:15 (IST) Congratulations to Jagan Reddyji on being sworn in as the CM of Andhra Pradesh. My best wishes to him, his new team of ministers and to all the people of the state. - Rahul Gandhi (@RahulGandhi) May 30, 2019 May 30, 2019 13:10 (IST) Only Mr Reddy took oath Thursday and his council of ministers is expected to be sworn in on June 7. May 30, 2019 13:06 (IST) Nagaland chief minister Neiphiu Rio congratulates Jagan Mohan Reddy. Congratulations, Y. S Jagan Mohan Reddy @ysjagan on taking oath as the Chief Minister of #AndhraPradesh. My best wishes for a successful tenure. May the state forge ahead under your leadership. @AndhraPradeshCM@YSRCParty - Neiphiu Rio (@Neiphiu_Rio) May 30, 2019 May 30, 2019 12:53 (IST) Christian, Islamic and Hindu prayers were recited by priests on stage as Jagan prayed after formally taking up the top job. May 30, 2019 12:44 (IST) Among the VIPs in attendance were Telangana Chief Minister K Chandrashekar Rao and DMK chief MK Stalin from Tamil Nadu. Mr Reddy and Mr Rao will fly to Delhi for Prime Minister Narendra Modi's swearing-in this evening for a second term. May 30, 2019 12:41 (IST) Jagan Mohan Reddy took oath at a grand public function at the IGMC Stadium in nearby Vijayawada May 30, 2019 12:03 (IST) Andhra Pradesh: Local priests meet CM designate YS Jagan Mohan Reddy and bless him, in Vijayawada, ahead of his swearing-in ceremony today. pic.twitter.com/isCHmwiyee - ANI (@ANI) May 30, 2019 May 30, 2019 12:00 (IST) KCR, MK Stalin to attend ceremony Telangana Chief Minister K Chandrasekhara Rao and DMK president MK Stalin are among the dignitaries who will attend the swearing-in ceremony. The YSR Congress chief has also invited Prime Minister Narendra Modi when he met him Sunday. May 30, 2019 11:52 (IST) Jagan Reddy will address specially invited dignitaries through video link After taking oath, Jagan Mohan Reddy is expected to specially address the invited dignitaries through the video link and present his vision and mission for building a new Andhra Pradesh. May 30, 2019 11:49 (IST) For the first time, special arrangements have been made at the Andhra Pradesh Bhavan in New Delhi for live streaming of the swearing-in ceremony. Ambassadors of various countries, representatives from unilateral and multi-lateral agencies, international donor agencies, industry associations, multinational corporations and international media have been invited to witness the event at the AP Bhavan, according to Resident Commissioner Praveen Prakash. May 30, 2019 09:58 (IST) Secunderabad MP Kishan Reddy is likely to get a Union Cabinet berth May 30, 2019 09:42 (IST) Venue of Jaganmohan Reddy's swearing-in-ceremony as Andhra Pradesh CM in Vijayawada was damaged due to heavy rain and strong winds. May 30, 2019 09:13 (IST) Vijayawada: Visuals from the venue of Jaganmohan Reddy's swearing-in-ceremony as Andhra Pradesh CM, heavy rain & strong winds lashed the area last night. pic.twitter.com/5XfrDdyghC - ANI (@ANI) May 30, 2019 May 30, 2019 08:31 (IST) Jagan Mohan Reddy alone will take oath today, says sources Jagan Mohan Reddy alone will take oath on Thursday while his Council of Ministers is likely to be constituted on June 7, party sources said. Jagan Mohan Reddy alone will take oath on Thursday while his Council of Ministers is likely to be constituted on June 7, party sources said. May 30, 2019 08:29 (IST) The YSR Congress won 151 of the 175 seats in the state Assembly, decimating the TDP headed by N Chandrababu Naidu,who became the first chief minister of the state after it was bifurcated to carve out Telangana five years ago. YSRC won 22 of the 25 Lok Sabha seats.
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Q: Order by pivot column I have two models, students and languages. Each student can speak n languages with a certain skill via pivot table student_language. For example Mike speaks English with a skill of 3 and german with a skill of 7. Here is the student model: class Student extends \Eloquent { public function languages() { return $this->belongsToMany('Language')->withPivot('skill'); } } And here is the language model: class Language extends \Eloquent { public function students() { return $this->belongsToMany('Student')->withPivot('quality'); } } How can I get a list of students that speaks a language, and sort them by their skill level? In Fluent it would be something like this, but I cannot use joins and need to write it in Eloquent: $students = DB::table('students') ->join('student_language', 'students.id', '=', 'student_language.student_id') ->where('student_language.language_id', '=', '1') ->orderBy("student_user.skill", "desc") ->get(); Thank you for any inputs. Edit: update A: I haven't check this but you can try this Student::with(['languages' => function($q) { $q->orderBy('pivot_skill', 'ASC'); }])->get();
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Bitcoin (BTC) tanked in November on the back of high volumes, raising the possibility that the market has, to some extent, capitulated. The largest cryptocurrency by market capitalization is currently trading at $4,000 – down 36 percent from its monthly opening price of $6,318 – according to CoinMarketCap data. That drop marks the biggest monthly loss of the year so far. Amid the losses, trading volumes jumped by 33 percent month-on-month to $158.48 billion – the highest level since May. It is worth noting that, at the start of the month, BTC was already down close to 70 percent from the record high of almost $20,000 reached in December 2017. So, November’s losses essentially mark an extension of the bear market (which had supposedly bottomed out near $6,000) with a high-volume drop to 14-month lows below $3,500. But BTC’s failure to produce a meaningful bounce despite the repeated defense of the 21-month EMA in five months to October might have left investors disappointed, resulting in the increased sell-off as they left the market. Amid these signs of capitulation, it is still too early to call a long-term bottom. In the last few days, however, prices have recovered from lows below $3,500 – possibly just bargain hunting after the sell-off, but potentially the start of a corrective rally, as the 14-day relative strength index (RSI) was reporting record oversold conditions a few days ago. Monthly chart On the monthly chart, BTC is set to close below the former support (now resistance) of the 21-month EMA for the first time since October 2015. A long-term bullish reversal would only be confirmed if and when prices clear the EMA, currently lined up at $5,977. 4-hour chart On the 4-hour chart, BTC has fallen back below the double top neckline support at $4,120, having faced rejection at the falling trendline. As a result, the immediate bullish outlook has been neutralized. The recent low of $3,474 could come into play if the immediate support at $3,771 (low of Wednesday’s bullish reversal candle) is breached. A break above the falling trendline, if confirmed, would bolster the already bullish technical setup and could yield a stronger rally toward $5,000. View The bitcoin market is likely showing signs of capitulation. A break below the neckline support of $4,120 has neutralized the immediate bullish outlook put forward by the double bottom breakout yesterday. A move below $3,771 (Wednesday’s low) would invalidate the bullish setup on the daily chart and allow re-test of the recent low of $3,474. A break above $4,250 (falling trendline resistance) would open up upside towards $4,761 (resistance as per the 4-hour chart). Disclosure: The author holds no cryptocurrency assets at the time of writing. Bitcoin image via Shutterstock; price charts by Trading View
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Stable oil-water emulsions have been a problem in many areas of the petroleum industry. In the production of oil under water-flood conditions, oil-water emulsions are obtained from the production wells. These emulsions must be broken in order to recover the oil in useful form. When cleaning oil tanker bilges, oil-water emulsions frequently form and present disposal problems. In the processing of crude oils, such as by desalting, stable emulsion layers are formed in the desalter resulting in the waste of valuable oil and the creation of a disposal problem. The stability of oil-water emulsions such as those described above is increased by the presence of fine suspended particles. It is recognized that the stability of oil-water-solid emulsions is a function of the composition, i.e., the relative amounts of oil, water and solids in the mixture as well as the type of oil and solids. The breaking of such emulsions requires alteration of this ratio. If the emulsion is classified as "water-in-oil", then the addition of miscible hydrocarbons to the emulsion generally only serves to swell the emulsion phase and does not lead to emulsion breaking. Thus, simple techniques such as diluting the emulsion with naphtha does not lead to the desired result. Removal of solids by filtration has a tendency to break the emulsion, but generally, since the emulsions are so viscous, filtration is extremely difficult. Centrifugation of oil-water-solid emulsions results in rather poor separation. U.S. Pat. No. 2,235,639 describes a procedure for the resolution of oil and water emulsions by adding a liquefied gas (such as ethane, butane, propane, etc.) to the emulsion. A liquefied gas is added to the emulsion under sufficient pressure to prevent vaporization of the gas. While the mixture is under pressure, the emulsion breaks, and water settles from the emulsion leaving the oil in a purified condition. While still under pressure, water is withdrawn and the oil is transferred to a secondary zone where it is heated to volatilize the hydrocarbon gas. U.S. Pat. No. 2,383,362 and 2,383,363 describe processes for the separation of water from hydrocarbon-water emulsions. More particularly, these patents relate to the breaking of tar emulsions and the separation of the water from the tar component by mixing a liquefied normally gaseous hydrocarbon solvent with the emulsions. The '362 patent is directed primarily to the use of propane whereas the '363 patent utilizes pentane as the liquid phase hydrocarbon. U.S. Pat. No. 3,696,021 describes the separation of oily sludges by mixing the sludges with a light hydrocarbon to form an oil-hydrocarbon phase and a water-solids phase. The oil-hydrocarbon phase then is heated to an elevated temperature to remove the light hydrocarbons which may be recycled, and the oil is recovered for further use. The light hydrocarbons disclosed as being suitable for use in the process include propane, butane, pentane, as well as mixtures and isomers thereof.
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package org.adempiere.ui.notifications; /* * #%L * de.metas.adempiere.adempiere.client * %% * Copyright (C) 2015 metas GmbH * %% * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as * published by the Free Software Foundation, either version 2 of the * License, or (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public * License along with this program. If not, see * <http://www.gnu.org/licenses/gpl-2.0.html>. * #L% */ /** * {@link NotificationItemPanel} callback. * * @author tsa * */ interface INotificationItemPanelCallback { /** Called when the notification was closed by the user */ void notificationClosed(NotificationItem item); }
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Why modularity emerges in evolution By simulating 25,000 generations of evolution within computers, Cornell University engineering and robotics researchers have discovered why biological networks tend to be organized as modules -- a finding that will lead to a deeper understanding of the evolution of complexity. The new insight also will help evolve artificial intelligence, so robot brains can acquire the grace and cunning of animals. From brains to gene regulatory networks, many biological entities are organized into modules -- dense clusters of interconnected parts within a complex network. The team discovered that evolution produces modules not because they produce more adaptable designs, but because modular designs have fewer and shorter network connections, which are costly to build and maintain. As it turned out, it was enough to include a "cost of wiring" to make evolution favor modular architectures. "Once you add a cost for network connections, modules immediately appear. Without a cost, modules never form. The effect is quite dramatic," says Clune. [emphasis mine]
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Ioannis Hatzopoulos Ioannis Hatzopoulos (, 1862–1918) was a Greek army officer, who commanded the IV Army Corps in 1916 and was interned with his men in Görlitz, Germany. Hatzopoulos was born in Patras in 1862. A career artillery officer, he fought in the Greco-Turkish War of 1897 and the Balkan Wars of 1912–13. In 1916, he was commander of the IV Army Corps in eastern Macedonia, with his headquarters at Kavala. The corps had been demobilized by the royal Greek government in Athens and numbered a fraction of its full strength. When the Bulgarian Army, with some German units, invaded eastern Macedonia in August 1916, Hatzopoulos was forbidden by the Greek government to offer any resistance. As a result, he and the bulk of his men—464 officers and 6373 soldiers—surrendered to the Germans and were interned for the rest of the war at Görlitz. These events provoked immediate reaction among the Greek officer corps, with the outbreak of a French-backed military revolt in Thessaloniki and the establishment of the Provisional Government of National Defence there, eventually leading to Greece's formal entry into World War I on the side of the Entente. Hatzopoulos never saw Greece again, as he died at Görlitz on 28 April 1918. References Category:1862 births Category:1918 deaths Category:20th-century Greek people Category:Hellenic Army officers Category:Greek military personnel of the Balkan Wars Category:Greek military personnel of the Greco-Turkish War (1897) Category:Greek military personnel of World War I Category:Greek prisoners of war Category:People from Patras Category:World War I prisoners of war held by Germany Category:Greek colonels
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To Mr. Theobald (Upon His Return to Providence) In Providence at fringèd eve Old Theobald takes his cap and cane, And where the antique shadows weave, Dreams his Colonial dreams again. Sees the pale periwigs that pass Pause delicately by, then far Past balustrades that shine like glass To seek his eighteenth century there. Dream, Theobald—close your tired eyes, Forget the ruder world around; Only these by-gone folks were wise, Only the vaniquish’d world was sound. Hold them an instant if you will, Shadows of perfume, light and flowers— We never knew their grace until You, by your genius, made them ours! —Samuel Loveman, The United Amateur (July 1926) Reprinted in Out of the Immortal Night (2004), 111-112 It seems very likely that Samuel Loveman was H. P. Lovecraft’s first Jewish friend, and his first homosexual one. Loveman was a great link in the web of correspondence among weird writers in the early 20th century; he traded letters with Ambrose Bierce, George Sterling, Clark Ashton Smith, and in 1917 answered the call of H. P. Lovecraft to return to amateur journalism. Upon acceptance, Lovecraft wrote: Loveman has become reinstated in the United through me. Jew or not, I am rather proud to be his sponsor for the second advent to the Association. His poetical gifts are of the highest order, & I doubt if the amateur world can boast his superior. —H. P. Lovecraft to Rheinhart Kleiner, 8 Nov 1917 Letters to Rheinhart Kleiner 119 This began an association that lasted the rest of Lovecraft’s life, mostly carried out through letters and the occasional visit. In the dream that became “The Statement of Randolph Carter” (1919), the character of Harley Warren was based on Loveman; the manuscript of Lovecraft’s Grecian fable “Hypnos” (1923) is dedicated “To S.L.”; together in 1922-1923 Loveman and Lovecraft edited The Poetical Works of Jonathan E. Hoag. Lovecraft’s praise of Loveman’s poetry in the pages of the National Amateur (Mar 1922) led to a critical battle in the columns of the Oracle and the Conservative between Lovecraft, Michael Oscar White, Frank Belknap Long, and Alfred Galpin. Through Loveman, H. P. Lovecraft met Hart Crane, and got his one and only job during his stay in New York City—stuffing envelopes, for a couple of weeks. They were both key members of the Kalem Club, a group of writers in New York so-called because the founding member’s last names all began with K, L, or M. One might add a hundred more little details and connections; they were close friends, booklovers, and fellow-poets. Loveman wrote at least three poems specifically dedicated to H. P. Lovecraft: “To Satan” (1923), “Bacchanale” (1924), and “To Mr. Theobald” (1926). This last poem refers specifically to Lovecraft’s pseudonym “Lewis Theobald, Jr.”, which in Lovecraft’s letters was sometimes shortened to “Theobaldus” or “Grandpa Theobald.” The occasion of the poem was Lovecraft leaving New York to return to Providence. In 1924, Lovecraft had quietly eloped to Brooklyn to marry Sonia H. Greene—a friend and fellow amateur journalist. Sonia had even invited both of them down to visit, in 1922, and would later write in her memoirs: Long before H. P. and I were married he said to me in a letter when speaking of Loveman, “Loveman is a poet and a literary genius. […] The only discrepancy I find in him is that he is of the Semitic race, a Jew.” Then I replied that I was a little surprised at H. P.’s discrimination in this instance—that I thought H. P. to be above such a petty fallacy—and that perhaps our friendship might find itself on the rocks under the circumstances, since I too am of the Hebrew people—but that surely, he, H. P., could not have been serious, that elegance of manner, cultural background, social experience and the truly artistic temperament, intellectuality and refinement surely do not choose any particular color, race or creed; that these attributes should be highly appreciated no matter where they may be found! It was only after several such exchanges of letters that he put the “pianissimo” on his thoughts (perhaps) and curtailed his outbursts of discrimination. In fact, it was after this that our own correspondence became more frequent and more intimate until, as I then believed, H. P. became entirely rid of his prejudices in this direction, and that no more need have been said about them. —Sonia H. Davis, The Private Life of H. P. Lovecraft 26 By 1926, however, the marriage had fallen apart. Loss of her job and ill-health had forced Sonia to relocate to the midwest, where Lovecraft would not follow. Living alone in the city, unable to find steady employment, and finally robbed of his clothes (and an expensive radio set that Lovecraft had been holding for Loveman), the Old Gent returned to Providence in April of that year. Hence Loveman’s letter; a cheery, intimate portrait of his friend, who he knew well enough to emphasize the Colonial architecture and history of Providence that Lovecraft so loved. A silver lining on a dark cloud that spelled the end of Lovecraft’s marriage, and a long absence from their physical company; meetings of the Kalem Club for Lovecraft would become fewer and farther between. In a memoir to his friend after his death, Loveman would write: Lovecraft’s stay in New York, after the separation from his wife (a tragedy to those who knew the inside of the affair), was one of complete rebellion against everything that the huge city had to offer. He hated the noise, the interminable rudeness of the inhabitants, the rowdy and rancid slums. […] He declaimed with flushed cheeks and a rising voice against (so he called it) “the mixed mongrel population—the very scum and dregs of Europe and the Near East,” that filled and permeated the area of the entire city. He anticipated with a heart-breaking intensity and longing that only his closest friends knew—a liberation and return to New England—back to his beloved Providence with its antique gables and narrow streets, to the Colonial reconstruction of what is now known to the readers of his weird fiction as “Arkham country.” —Samuel Loveman, “Howard Phillips Lovecraft” (1948) Reprinted in Out of the Immortal Night 221 Later in Loveman’s life, when Lovecraft’s letters began to be published and after correspondence with Sonia H. Davis, he became aware of the depths of the Old Gent’s antisemitism in the 1930s and roughly denounced his old friend: During that period I believed Howard was a saint. Of course, he wasn’t. […] Lovecraft had a hypocritical streak to him that few were able to recognize. Sonia, his wife, was indubitably his innocent victim. Her love for him blinded her to many things. Among the things he said to her was, “Too bad Loveman’s a Jew; he’s such a nice guy.” I was, in the early phase of our friendship, an easy mark. He was, however, loyal in his appreciation of me as a poet. —Samuel Loveman, “Of Gold and Sawdust” in The Occult Lovecraft (1975) 22 It is impossible to appreciate “To Mr. Theobald” without understanding the larger context of how it came to be rewritten, the nature of their friendship at that point…a friendship that Loveman would later look back on with such evident disappointment, in himself and in Lovecraft. Fans of Lovecraft’s fiction and poetry can certainly relate; too close a look at one’s literary heroes often reveals flaws that were not immediately apparent on that first happy exposure to their work. Loveman’s focus in later life is on Lovecraft’s antisemitism. No comment from Lovecraft was ever made in print about Loveman’s homosexuality, and it is not clear if he was even aware that Loveman was gay, although there are certainly hints in the letters that Lovecraft knew about Hart Crane, so it is possible. Still, there is something in these poems dedicated to Lovecraft—and the poems that Lovecraft wrote dedicated to Loveman—which are melancholy today, pressed flowers of a real friendship. Lovecraft was serious when he wrote: So like in name, in art so much the less, Let Lovecraft lines to Loveman’s Muse address: How blest art thou, who thro’ thy pow’r of song Beside Pierus’ sacred fount belong. —H. P. Lovecraft, “To Samuel Loveman, Esquire, on his Poetry and Drama, Writ in the Elizabethan Style” (1915) Reprinted in The Ancient Track 94 Bobby Derie is the author of Weird Talers: Essays on Robert E. Howard & Others (2019) and Sex and the Cthulhu Mythos (2014).
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Denmark at the 2019 World Beach Games Denmark competed at the inaugural World Beach Games in Doha, Qatar from 12 to 16 October 2019. In total athletes representing Denmark won one gold medal and the country finished in 14th place in the medal table. Medal summary Medalists References Category:Nations at the 2019 World Beach Games World Beach Games
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There has been a lot of speculation around the tech blogosphere about what firmware Google Glass is running. Most people have assumed that Google had created a proprietary firmware to run what is obviously a unique hardware set up. But today during Google's quarterly earnings call CEO Larry Page confirmed that Google Glass does indeed run a modified version of Android. Page said "obviously, Glass runs on Android, so [Android] has been pretty transportable across devices, and I think that will continue." Among other things this certainly speaks to the flexibility and adaptability of Android. It is one thing to see Android run on cameras, laptops, smart phones, tablets and even one refrigerator. But it is quite another to see Android powering this type of wearable computing device. This is great news for Android developers who might be looking to port their application over to Glass in the near future. Glass running Android means that the two will share a common language and this should aid in the speedy development of a vibrant third-party developer community around Glass. Of course nothing will motivate creative developers to come up with innovative ways to use Google Glass like popularity among consumers. At the end of the day no matter how hard Google works to promote Glass it will be up to the early adopters among us, as well as the average consumer to make the Google Glass ecosystem viable. We can also assume that the rumored Google smart watch will almost certainly run a version of Android as well. Since a smart watch won't necessarily be as wildly different in terms of hardware from a smart phone, I would think that porting an app over to a smart watch should be more simple than developing an app for Google Glass. It will be interesting to see how consumers react to the wearable computing devices that will be hitting the market over the next couple of years. Do you see yourself purchasing either Google Glass or a Google smart watch? Let us know in the comments section.
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It is generally desirable in modern radiotelephone communications to maintain a relatively high average carrier modulation level while not exceeding a predetermined maximum modulation level. When a modulated carrier signal is detected in a radio receiver, the output of the receiver detector follows the deviation of the received modulated carrier. It is desirable to modulate the carrier at as high a level as possible (consistent with bandwidth limitations imposed by law and by transmitter and receiver design) to increase the useful receiver output level, and thus increase communications range and decrease degradation of received signal quality due to noise fading and other factors. Transmitted carrier modulation level is determined by the amplitude of the intelligence (e.g., voice) signal applied to the modulating circuits (typically, the oscillator or frequency synthesizer in frequency modulation transmitters). Signal processing such as amplitude compression, amplitude limiting and the like can be used to increase the average carrier modulation level. Ideally, average carrier modulation level during useful signal transmission should remain relatively constant at or near the maximum permitted modulation level despite changes in parameters that may affect transmitter modulation level (e.g., carrier frequency, modulating signal characteristics, rf power output, etc.). Variation in modulation level with change in carrier frequency has not been a major problem in past frequency modulation transceivers because transceivers have generally been incapable of operating outside a relatively narrow operating bandwidth. Hence, most existing FM digital frequency-synthesized transmitters do not provide compensation of carrier modulation level for changes in transmitter operating frequency. A typical prior-art synthesized transceiver is capable of operating anywhere within a 20 MHz range, and has a maximum carrier deviation level which varies between about 3 and 5 kHz as carrier frequency is changed. In such prior-art transceivers, modulation level (i.e., the effective gain of the modulating circuits) is set to a fixed level such that a predetermined maximum modulation deviation level (e.g.. 5 kHz for narrow-band FM) is never exceeded. U.S. laws governing radio communications do not require a minimum deviation level, but do set a maximum permissible modulation level (and associated envelope bandwidth)--so that adjustment of maximum modulation level is sufficient to guarantee that the transceiver always operates within the modulation level limits set by law no matter what the carrier frequency is set to. This solution unfortunately has the severe disadvantage that the transceiver carrier modulation level is at or near the maximum permissible level only for a few of the many frequencies at which the transceiver is capable of operating, and is far less than this maximum level at many (if not most) transceiver operating frequencies. Communications range and signal quality and intelligibility are degraded on many transmitter operating frequencies as a result. FIG. 1 is a graphical illustration of carrier modulation deviation level of an exemplary frequency-modulated radio transmitter plotted against transmit frequency for various methods of modulation deviation level compensation. As the curves marked "A" in FIG. 1 shows variations in modulation deviation level of an uncompensated transmitter can be as much as 3 dB with a change in operating frequency of 20 MHz. To add to this problem, variations in modulation deviation level between different production units may vary by as much as 1 dB or more (as is depicted by three different curves A-1. A-2 and A-3). Thus, the modulation deviation of a completely uncompensated transmitter might fall anywhere within the limits between curves A-1 and A-3. By adjusting the deviation at center band (460 MHz in the example shown) with a variable circuit component such as a potentiometer, the total variation is limited to that indicated by curve A-2 (still 3 dB for a change in operating frequency of .+-.10 MHz). Some countries of the world regulate minimum as well as maximum FM deviation levels, so that some correction of modulation level with change in transmitter operating frequency is necessary if legal requirements are to be complied with. For example, some transceivers provide a non-linear circuit within the transmitter modulator which adjusts the audio modulation level as a function of synthesizer tuning voltage. This non-linear circuit provides some degree of modulation level correction, but the deviation level is not programmable for individual operating frequencies. The curve of FIG. 1 marked "B" shows the variation in modulation deviation level for a transmitter having additional non-linear circuit components as described above. Such additional compensation circuit components can reduce variation in modulation level to less than plus or minus 0.5 dB. Unfortunately unit-to-unit variations in modulation deviation level requires overall modulator circuit gain to be adjusted (e.g.. by adjusting a variable resistor controlling the gain of one of the modulator stages) so that the average modulation level is as high as possible consistent with legal requirements. Such adjustments are difficult and time-consuming to make, and must be individually performed for each unit. A technique which provides constant transmitter modulation deviation level over a wide range of transmit frequencies and which also compensates for variations between transmitter units would increase effective transmission range and ensure compliance with pertinent legal requirements, and would therefore be highly useful. Another problem which often plagues modern digital mobile radio transceivers is the generation, by the internal circuitry of the transceiver itself, of signals which interfere with reception of desired signals. Sophisticated modern communications devices generally employ high-speed synchronous digital circuitry (e.g.. microprocessors) driven by clock synchronizing signals. To obtain the speed performance such digital circuitry is capable of providing, it is necessary to generate one or more clock synchronizing signals of relatively high frequency (e.g.. 4 MHz). Harmonics of the clock frequency sometimes fall within the receiver operating frequency band, causing spurious responses which may interfere with the operation of the radio transceiver. For instance, suppose a radio transceiver capable of operating in the 400 MHz range with a receiver bandwidth of 12 kHz is controlled by an internal microprocessor driven by a crystal oscillator operating at 4 MHz. If the receiver of this transceiver is tuned to an operating frequency of 464.000 MHz, a clear-channel spectrum of 463.994 MHz to 464.006 MHz must be maintained to avoid interference with signals to be received. Unfortunately, an on-channel spurious response may be caused by the 116th harmonic of the microprocessor oscillator (4.0 MHz.times.116=464.000 MHz). One solution to the problem described above is to significantly improve the shielding between the radio frequency circuitry and the digital circuitry of the transceiver so that no signals generated by the digital circuitry can find their way into the RF circuitry. Because of the high sensitivity and the compactness of modern radio transceivers, it is extremely difficult to provide sufficient shielding to guarantee complete freedom from receiver interference. Another method sometimes used to reduce interference of received signals caused by spurious signals generated by a microprocessor clock oscillator is to select an oscillator frequency which is not harmonically related to any frequencies desired to be received. Although this solution works well for transceivers having only a few fixed operating frequencies, modern microprocessor-controlled radio transceivers are capable of operating on a large number of channels and can be programmed (or reprogrammed) in the field to operate on new or different channels than those selected at time of production. It is sometimes impossible to locate a clock oscillator frequency which is not harmonically related to any of a large number of possible operating frequencies. Moreover, the clock oscillator frequency may have to be changed every time the transceiver is programmed to operate on new or different operating frequencies, thereby increasing field servicing time, cost and complexity. An arrangement which guarantees complete freedom from internal oscillator-generated receiver interference regardless of receive frequency would be very valuable and useful.
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