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Hello doctor, This is regarding my 87-year-old father who is physically fine perfectly. But, the whole day and night, he curses my mother and will not let her sleep. In his mind, he thinks that everyone is trying to cheat him and because of that he is not able to sleep. Sometimes he becomes violent also. Currently, he is on Clonazepam 5 mg. Please help. | urgent |
Hello, 6 months ago I had a manic depressive episode. I was put on Wellbutrin 300mg/day, it has worked well however I am feeling much better now and am starting to get back into social life activities. Being 18 and living in an apartment with 4 others we tend to enjoy drinking. My roomates smoke cannabis too however my phycologist told me that cannabis will depress my mood and flush out the Wellbutrin. However I do enjoy drinking and have been drinking about 4 times a week heavily. Sometimes blackouts occur, but drinking is what I enjoy to do sometimes. Of course my health is number one. What health risks are on the line when it comes to heavy drinking and Wellbutrin,, besides blackouts. | non-urgent |
my 13 year old daughter stayed home frim schookl yesterday since she was vomitingi figured it was the stomach virus going aroung, but tonight (after not throwing up since yesterday afternoon) she suddenly threw up grey, lumoy vomitshould I take her to the er? | urgent |
I have a friend that has mental issues she drinks she takes prescription drugs and now she admitted to me she is stealing for no reason she has money so she does not need to steal. She lost her daughter to cancer in March she does suffer from depression and I believe she has a eating disorder . How can I help her I dont think her pills are helping with her depression. | non-urgent |
The research results in the last two decades show the important role of pekarangan as a micro-scale landscape unit in providing space for growing various types of plants, i.e., multi-layers from the grasses to the trees, livestock, and fish. Pekarangan is defined with distinctive spatial patterns and elements as a representation of the harmonious relationship between the owner and the ecological character. Perceptions and preferences based on different social, cultural, and environmental factors shape the pekarangan pattern and function to become more diverse as a form of community local wisdom. The important role of pekarangan needs to be deeper elaborated in efforts to increase community immunity during the Covid-19 pandemic. Pekarangan has great potential to be developed as a mitigation and rehabilitation space by providing a variety of medicinal plants as well as outdoor activity spaces with a healthy environment quality. This research was designed for three years with three main approaches: (1) inductive method, which focuses on building theory from practices that have been known and carried out for generations, (2) implementation as an effort to actualize local knowledge, (3) multiplicative for the benefit of the important value of pekarangan. Studies start from basic research of pekarangan;research on the development of spatial planning and elements forming pekarangan;research on nutritional content contributed from pekarangan products. Data were obtained through pekarangan mapping, structured questionnaires at four selected locations in Cisadane, Citarum, Kali Progo, and Brantas Watersheds. The results of this research are expected to be implemented in public spaces on a meso scale and macro scales. | non-urgent |
Hello, for the past two days I ve been feeling as if a hair all has been stuck in the back of my throat. I keep swallowing but it feels stuck in there. I m also experiencing heartburn-like pain in middle of my chest. We just got two new puppies yesterday. What could this be? | urgent |
hello doctor. I am a 20 year old male with a strange condition and its a bit descriptive. Your help will be very valuable to me. So let me start. I was a smoker once. I used to smoke Marijuana from about July 2013 and left smoking after February 2014. I also smoked cigaretes from about December 2013 to February 2014. The reason I quit smoking was because I had a very bad hangover after smoking marijuana. When I was high I was thinking if it could kill me and all of a sudden I thought I am going to die and my heartbeat raced and I was full of fear, It might have been a panic attack but I thought it was a heart attack and I became restless and started running and splashing my face with water, I was terrified. after few hours I was normal but my fear remained for about 2 days and after that i became completely normal. Few weeks later(in march 15 approximately) at night I had a slightly sharp pain in my upper left abdomen and I thought it was a heart attack and I had another episode of that panic but this time it lasted only for a minute(may be even less and might have been due to gas) but after this episode I got very depressed thinking that I might have developed a heart condition or lung problem or even stomach cancer. I used to remain depressed all day and was also frightened at the same time for about a week. I used to search the internet about everything that could have caused it. After a week my paranoia reduced but was not completely gone. I had my exams that week and after the exams were over my paranoia reduced but was still there to cause me stress. after few months during my next exams my stress returned with a vengeance and I used to feel headache and inactive all day and I thought that I still might have some disease related to smoking and after the exams were over the symptoms were all gone. It has been almost 5 months now since that panic episode. but whenever I get mild chest pain mainly due to gas or mild heartburn I get anxious. Is there a way out? I know that I have no serious condition cause I didn t get any check-up after that episode and in these few months more symptoms should have appeared. Your help will be highly appreciated. Thank You. | non-urgent |
OK. Had sever tightening of chest. Took two nitros. Wound up extremely dizzy. Then my blood pressure was 70/40 and has been rising some but still low. I ve been treated for HBP and for my heart. Didn t call in time to reach my cardiologist. Now there is a slight metalic taste in my moth. | urgent |
What condition is suggested by the presence of myoglobinuria and hemoglobinuria? | non-urgent |
My 19 year old son is having the following | non-urgent |
Hello doctor, I am sweating too much I guess. I am not sure if it is because of the heat here but I sweat. Pleae sugget me something which I can apply to my body. So it does not sweat much and I look fresh and I do not smell. | non-urgent |
I am suffering from nephrotic syndrome... my doctor have prescribed me all type of tablets.. finally i am taking renalog and losartan 50 mg tablet... due to my family background i cant able to buy renalog tablet instead of that can i take ranitide tablet given by gov.hospital? plz reply sir.. | urgent |
hellow doctor, i am married 3 years. i am trying to get a pregnant for the past 3 years.i have a problem of irregular periods(PCOS) and hyper thyroidism. By only taking a medicine (GLYCOMET 500MG thrice a day) i getting my period regular with 31-32 days cycle.my husband took a surgery for VERICOCEL on 8th dec 2009.Then we have no contact for one month.After that we have a contact on the date of 12 to the date of 20th (febr) i also took a tablet LETROZ 2.5mg,FOLIC ACID & M2TONE with doctor advice.now i have a little stomach pain too for coming menses.please tell me there is a posibilities to get a positive results. And also tell me when i getting MICROGEST(MICRONISED PRGESTERONE) tablet. i already use the tablet (twice a day) from 22nd onwards, is this correct or not? my age- 25,female | urgent |
BACKGROUND: Calf diarrhoea is the most serious issue in the livestock industry, resulting in significant financial losses. METHODS: A study was undertaken in 32 urban and peri‐urban dairy farms of Hawassa town to isolate E. coli from diarrhoeic calves, assess associated putative factors related to the occurrence, and the evaluate antibacterial susceptibility patterns of isolates. A convenience sampling technique was performed for the selection of these dairy farms and calf samples. A total of 68 faecal samples were collected directly from the rectum of diarrhoeic calves. The faecal samples were confirmed as E. coli O157: H7 positive using the latex agglutination test. RESULTS: In this study, 47(69.1%) samples were positive for E. coli, of which 22 (46.8%) were identified as E. coli O157:H7 strains based on their latex agglutination character. Factors such as frequency of calf house cleaning, type of supplement provided, and method of colostrum feeding were significantly correlated (p < 0.05) with calf diarrhoea, while the other risk factors had no significant association. Antibiogram of E. coli O157:H7 isolates showed that the isolates were highly sensitive to gentamycin, ceftriaxone, trimethoprim‐sulphamethoxazole, and ciprofloxacin and were found to be resistant to tetracycline, kanamycin and amoxicillin. CONCLUSION: Our findings revealed that calf diarrhoea is still a major health problem of calves in the study area. Hence, improved calf and farm management practice, an ad libitum quantity of colostrum, and good farm hygienic practices should be ensured. This study also revealed that some antibiotic‐resistant E. coli O157:H7 isolates need to be further investigated for their public health implications. | urgent |
Abstract Aims We assessed how altered diagnostic processes and criteria for gestational diabetes mellitus (GDM) recommended by the United Kingdom (UK), Canada and Australia for use during the COVID-19 pandemic would affect both GDM frequency and related adverse outcomes. Methods Secondary analysis of 5974 HAPO study women with singleton pregnancies who underwent 75g OGTTs and HbA1c assays between 24 and 32 weeks’ gestation and who received no treatment for GDM. Results All post COVID-19 modified pathways reduced GDM frequency - UK (81%), Canada (82%) and Australia (25%). Canadian women whose GDM would remain undetected post COVID-19 (missed GDMs) displayed similar rates of pregnancy complications to those with post COVID-19 GDM. Using UK modifications, the missed GDM group were at slightly lower risk whilst the women missed using the Australian modifications were at substantially lower risk. Conclusions The modifications in GDM diagnosis proposed for the UK, Canada and Australia result in differing reductions of GDM frequency. Each has both potential benefits in terms of reduction in potential exposure to COVID-19 and costs in terms of missed opportunities to influence pregnancy and postpartum outcomes. These factors should be considered when deciding which protocol is most appropriate for a particular context. | non-urgent |
I am 23 years old and i had transvaginal ultrasound for follicle maturation(dated 8 march 2011). my report is :para 0+0, The uterus is anteverted & normal size, measuring 6.2x2.4x3.6cm, The endometral thickness is approx 1.1cm, Right Ovary measuring: 3.3x2.4cm(Showing multiple follicles). Largest follicle measuring 1.2x1.0cm. Left Ovary: Left ovary measuring: 3.0x2.0cm(Showing multiple follicles). Largest follicle measuring 1.7x1.7cm. No adnexal mass & no free fluid seen in cul-de-sac. IMPRESSION: Mature follicles seen in left ovary. please tell me my report is ok or not.one year ago i married but no babby why i have any problem in my report please advice me if my report is ok tell me any advice for my husbant. if any english mistake in above mention detail please correct.i am waiting for your kind and soon reply. | non-urgent |
What does the term "anemia of chronic disease" mean? | non-urgent |
I have Mononucleosis and Group B Streptococcus,Here's what happened:- I was really tired for 4 or 5 days- After that, I got a sore throat and I was still kind of tired- Now, I have a horrible sore throat and I cringe every time I swallowI've had a sore throat for about 10 days, and all of my symptoms started about two weeks ago. About 3 days ago, I was diagnosed with Mononucleosis. Today, my doctor called and said I had Group B Streptococcus. What is this strep disease? My doctor said they didn't have any medication to treat this type of strep. The only stuff I can find online about group B strep is about when pregnant women have it. I'm 19 and I'm not pregnant. Can someone explain what all of this is? Thanks! | non-urgent |
What is the name of the leukodystrophy that is characterized by optic atrophy and the presence of globoid cells? | non-urgent |
Infectious bronchitis virus (IBV), a gamma-coronavirus, causes infectious bronchitis (IB), a major respiratory disease of chicken. Its high mutation rate in conjunction with recombination of the RNA genome constantly creates IBV variants that are difficult to control by currently available vaccines. In this study, we addressed the question whether small-scale holdings might harbor IBV variants that serve as a reservoir for newly emerging variants. Egyptian IBV isolate EGY/NR725/2016 (NR725/16) from a small-scale broiler farm was assigned to genotype I, clade 23 (S1:GI-23), based on partial S1 gene sequences and corroborated by full genome sequencing. Analysis of the S1 gene established three subclades for historical IBV strains (S1:GI-23.1, S1:GI-23.2.1 and S1:GI-23.2.2) and confirmed NR725/16 as being part of a separate fourth subclade (S1:GI-23.3). Samples from the years 2018 and 2019 revealed that the new subclade prevails in Egypt, carrying fixed mutations within the hypervariable regions (HVR) 1-3 of the S1 protein that affect two neutralization sensitive epitopes at sites 294F, 297S and 306Y (48.2) and 329R (62.1). In addition, recombination was recognized in isolate NR 725/16, with intra-subtype mixing for the entire genes 3ab and E and inter-subtype mixing for the entire gene 6b with a close match to QX like viruses of genotype GI-19. Further analysis of gene 3ab detected the homologous gene pool to NR725/16 in samples from 2013 (3ab:C) and closely related 3ab genotypes in IBV Egyptian isolates from 2016, 2018 and 2019. These data prove a flourishing exchange between poultry holdings with a common gene pool. The continued circulation of viruses harboring genes S1:GI-23.3 and 3ab:C indicates an evolutionary advantage of this combination possibly by combining antigenic escape with modulated pathogenicity to facilitate IBV spread in the vaccinated poultry population in Egypt. | non-urgent |
I was recently diagnosed with cellulitis in my left breast. During the ultrasound a large mass was discovered. I go for follow up appointments.... The usual tests, mammogram, ultrasound, MRI and possible biopsies. What kind of wait time can I expect on my biopsies and MRI results? | non-urgent |
Hello doctor,There is a white discharge coming from my penis, please. | urgent |
I have been taking the contraception pill called Yaz for the past 2 months. i have gone straight onto the next pack with no period as recommended by my GP. This is because I get headaches at period time and painful breast tenderness. I have had no breast tenderness but have had a dark brown discharge every day, and several light headaches. The discharge is more concerning.....and annoying! Please help. Linda | non-urgent |
What is the association between non-ST elevation myocardial infarction and post-coronary artery bypass grafting (CABG)? | non-urgent |
What are the symptoms of Acute respiratory distress syndrome? | urgent |
I have 2 bad hips. Right one went first, better after cordizone shot. Left hip acted up, got a shot there but outcome was disappointing--technique was different and rushed through--left hip began getting much worse soon after. My question--when is joint damage too advanced to have replacement done? | non-urgent |
PLEASE HELP!! :( My 5year Old Son developed 3 red Bumps on his neck which resembled mosquito bites,but tonight as he was getting ready to take his shower i noticed the bumps spread to the back of his legs/thighs and his private area(including testicles) what could have caused this? This has never happened to him before | non-urgent |
Hi. I have had 5 episodes recently of severe abdominal pain. Each time the only thing in common is that I have eaten something containing almonds. I have been eating almonds for years...how is it possible that they suddenly are causing me so much pain?? | non-urgent |
my husband was out side yesterday on the front lawn bending over to pick something up off the ground suddenly he fell on the ground he said he could not move at all and his right leg felt very heavy like a block of wood, question should we be worried he is 55yold | non-urgent |
BACKGROUND AND AIM: DM patients' antibody response after the COVID-19 vaccine is still unknown amid the COVID-19 vaccination rollout. This study aimed to explore the SARS-CoV-2 antibody response or seropositivity among DM patients following the COVID-19 vaccine administration. METHODS: We performed a systematic review of the literature consisting of observational or cross-sectional studies, which reported the antibody serology or seropositivity among DM patients by following the PRISMA 2020 guidelines. RESULTS: Eight studies with a total of 64468 patients were identified, and 5156 (7.9%) of them had diabetes. Most studies showed that antibody response and seropositivity in DM patients were lower than healthy population after one until four weeks following full COVID-19 vaccination dose. CONCLUSION: The antibody response and seropositivity after the COVID-19 vaccine in DM patients were lower than in healthy subjects. Therefore, DM patients are expected to receive vaccines according to the dose and schedule appropriately and might be prioritized to receive vaccine boosters. | non-urgent |
Hi doctor, During masturbation I just rub the tip of the penis and not the entire penis. Is it a wrong way of doing? I do not get excited during sex and unable to ejaculate. Only, rubbing the tip of the penis gives me excitement. Also, two weeks ago, I have undergone circumcision as my foreskin did not retract. Before circumcision too, I have the same problem. Please help. | non-urgent |
I think I was misdiagnosed with MS. I was later diagnosed with LYmes Disease based on a blood test sent to a specialty lab. This diagnosis came after 10+ yrs. of my MS diagnosis. Is there still a possibility of the Lymes being treated and close to being cured? | non-urgent |
Hi, I've been feeling very hungry in the morning when I woke up. I'm not sure if this was hunger or if my stomach was hurting a lot however. So I took a stool softener after eating 2 sandwiches and felt slightly better for 3 hours. When I got home I had to run to the toilet all of a sudden. When I sat on the toilet, I was pooping a brown liquid at the same rate at which I urinate. I do not think a stool softener is supposed to do this. | non-urgent |
I have a sharp debilitating pain in my left shoulder blade. It came on all of a sudden about 2 days ago. Range of motion other than bending over is not affected and if I lay down or recline the pain goes away or at least to an ache. What could this be and what can I do to treat? | non-urgent |
Hello doctor, I am a 66 year old female with RA. Some years ago (about 13years ago) one of the options suggested to me was fusion. My new doctor has stated that I am a good candidate for wrist replacement. How long has this new procedure been used and is it safe? Will the whole wrist be replace? I want to know as much as possible before making a final decision. What are the replacement parts made of? Will I feel them moving and will I still have flexibility in my wrist and fingers still? | non-urgent |
BACKGROUND: A novel avian-origin influenza A(H7N9) caused a major outbreak in Mainland China in early 2013. Exposure to live poultry was believed to be the major route of infection. There are limited data on how the general public changes their practices regarding live poultry exposure in response to the early outbreak of this novel influenza and the frequency of population exposure to live poultry in different areas of China. METHODOLOGY: This study investigated population exposures to live birds from various sources during the outbreak of H7N9 in Guangzhou city, China in 2013 and compared them with those observed during the 2006 influenza A(H5N1) outbreak. Adults were telephone-interviewed using two-stage sampling, stratified by three residential areas of Guangzhou: urban areas and two semi-rural areas in one of which (Zengcheng) A(H7N9) virus was detected in a chicken from wet markets. Logistic regression models were built to describe practices protecting against avian influenza, weighted by age and gender, and then compare these practices across residential areas in 2013 with those from a comparable 2006 survey. PRINCIPAL FINDINGS: Of 1196 respondents, 45% visited wet markets at least daily and 22.0% reported buying live birds from wet markets at least weekly in April-May, 2013, after the H7N9 epidemic was officially declared in late March 2013. Of those buying live birds, 32.3% reported touching birds when buying and 13.7% would slaughter the poultry at home. Although only 10.1% of the respondents reported raising backyard birds, 92.1% of those who did so had physical contact with the birds they raised. Zengcheng respondents were less likely to report buying live birds from wet markets, but more likely to buy from other sources when compared to urban respondents. Compared with the 2006 survey, the prevalence of buying live birds from wet markets, touching when buying and slaughtering birds at home had substantially declined in the 2013 survey. CONCLUSION/SIGNIFICANCE: Although population exposures to live poultry were substantially fewer in 2013 compared to 2006, wet markets and backyard poultry remained the two major sources of live bird exposures for the public in Guangzhou in 2013. Zengcheng residents seemed to have reduced buying live birds from wet markets but not from other sources in response to the detection of H7N9 virus in wet markets. | non-urgent |
Hi my 6 year old son visited the doc today for discoloration of his cheeks. Both side have white blotches with the left side more blotchy. The doc said it was some fungus that happens in march? He said to put lamisil cream on it, I have read many bad things about the cream? What are your thoughts | non-urgent |
Who should avoid the administration of MMRV and influenza (intranasal) vaccines due to contraindications, and what is the reason for this? | non-urgent |
Among the various human attitudes toward a pandemic, along with fear, despair and anger, there is also an urge to praise the catastrophe or imbue it with some sort of hope In 2020 such hopes were voiced in the stream of all the other COVID-19 reactions and interpretations in the form of predictions of imminent social, political or economic changes that may or must be brought on by the pandemic, or as calls to “rise above” the common human sentiment and see the pandemic as some sort of cruel-but-necessary bitter pill to cure human depravity or social disorganization Is it really possible for a plague of any kind to be considered a relief ? Or perhaps a just punishment? In order to assess the validity of such interpretations, this paper considers the artistic reactions to the pandemics of the past, specifically the images of the plague from Alexander Pushkin’s play Feast During the Plague, Antonin Artaud’s essay “The Theatre and the Plague” and Albert Camus’s novel The Plague These works in different ways explore an attitude in which a plague can be praised in some respect The plague can be a means of self-overcoming and purification for both an individual and for society At the same time, Pushkin and Camus, each in his own way and by different means, show the illusory nature of that attitude A mass catastrophe can reveal the resources already present in humankind, but it does not help either the individual or the society to progress © 2021, Gaidar Institute Press All rights reserved | non-urgent |
i have been suffering from chronic neck and spine pain for 8 or more years ive been to pain management few times in the past and until i can get a Dr that can help me and not just give me a lot of medication how can i get some relief of the pain off my neck and spine | non-urgent |
My son is 10 and goes on 3-4 mile runs with me a couple times a week. He does not get winded, and has incredible endurance. Is this ok? Some people have told me it is not good for him. Obviously if he complained of pain or exhaustion I would not let him. He loves it! | non-urgent |
Hi! I been having yellow liquids coming out from both of my foot.At first they looked like bug bites and they itch, but eventually some yellow/white liquid will come out!After a while the skin around the bump area will turn black.I don't know what it is... | urgent |
Hi. I m a 19 yr old female. For about 3 or 4 years I ve been having this problem. First I feel like all my blood rushes to my head &I get light headed &feel butterflies . Then my heart starts beating fast. I don t just mean fast as in just ran a half mile but probably double that. Like 5 or 6 beats per second. You can see my chest beating. I ve had other people feel it as well. It also gives me very sharp pains in my chest. It hurts to breathe or swallow. It feels like there is a truck tire sitting on my chest. Then it just stops. Not gradually. Just instantly stops. This happens very randomly. I could be working or lying down or folding laundry. I ve been to the hospital multiple times&they ve never found anything wrong. I need to know what s wrong. | non-urgent |
my name is hafiz from pakistan i asked you for i used my hand frome 16 years to 25 years when without women now i get marriage i was a problems of doing with myh wife at night what should i do tell me simple answer for me my english is verey weak sorry. | non-urgent |
sir am a allergy patient now am suffering from urticaria also. i am taking cetrizine from last 5 years and i cannot stop this . sir am 24 yrs old am tensed that is this tab leads me to impotent. sir is there ant problem for taking this tab or is there any solutn 4 me to stop this | non-urgent |
Hallo dr I have been married for 8 months... My inlaws are very eager for me to conceive After marriage I had regular periods for 5 months After that i missed period for one month Since then i am having irregular bleeding For 15 to 16 days and then after a week or two again i am having bleeding I got an ultrasound done..and it says pco And horseshoe kidneys Actually after 3 months of my marriage i had taken duphaston for 3 months and clomid for five days My husband stays abroad So he was coming for 15 days I took clomid right after my periods stopped. then i wasnt feeling much well So after medical examination i came to know that i dint have proper intercourse Now i have stomach cramps and headaches all the time And my periods wont stop Its 17th day today I was undergoing unani treatment from a certain dr But it wasnt effective Then last week i met a gynacologist and shes giving me herbal treatment..still periods dint stop So she is suggesting me duoleton Which i am scared of taking after all this What should i do Please help | non-urgent |
hi, i had unprotected sex with my 26 yr old wife last month. she has missed her periods last month. Is she expecting and if yes then how to confirm it. She is in Philadelphia alone right now n is bit shy to consult a dr alone. Is there any procedure to check at home.? We are very excited about it and are ready to increase our family. please suggest. | non-urgent |
I have a friend that thinks he has lung cancer and is afraid to go to the dr for fear of what he will find out. His symptoms include a chronic pain in his back left side, diarrhea, nausea, a cough that is intermittent and a couple of spots on his skin that are discolored. Are these typical symptoms? | non-urgent |
Hi doctor, I am a 22 year old female. I have a dusky skin that is brown skin. I want to become fair. Can I use Kojivit gel? Or any other dermoatology cream can I use? My hands are also brown in color and full of tan. Do you suggest any creams to get fair? I want to become fair as my marriage is going to get fixed by next year. Please suggest me some creams, so that it should not show any side effects. Also, how long I should use it? If I use anything, then will it have any effect in case of pregnancy, etc? Please help me. Thanks in advance. | non-urgent |
was digging and shoveling 3 days ago and next day started having pain in my upper stomach area. pain comes and goes and has not kept me from normal activity. i'm 75 and very active. non smoker and drinker. i'm concerned about possible aorta anyuerism. I have 2 iliac anyuerism 2.6 and 2.8 as of last testing 2017. could my pain be just muscle strain or worse? I am concerned. mike | non-urgent |
There is an unmet need for pre-clinical models to understand the pathogenesis of human respiratory viruses; and predict responsiveness to immunotherapies. Airway organoids can serve as an ex-vivo human airway model to study respiratory viral pathogenesis; however, they rely on invasive techniques to obtain patient samples. Here, we report a non-invasive technique to generate human nose organoids (HNOs) as an alternate to biopsy derived organoids. We made air liquid interface (ALI) cultures from HNOs and assessed infection with two major human respiratory viruses, respiratory syncytial virus (RSV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Infected HNO-ALI cultures recapitulate aspects of RSV and SARS-CoV-2 infection, including viral shedding, ciliary damage, innate immune responses, and mucus hyper-secretion. Next, we evaluated the feasibility of the HNO-ALI respiratory virus model system to test the efficacy of palivizumab to prevent RSV infection. Palivizumab was administered in the basolateral compartment (circulation) while viral infection occurred in the apical ciliated cells (airways), simulating the events in infants. In our model, palivizumab effectively prevented RSV infection in a concentration dependent manner. Thus, the HNO-ALI model can serve as an alternate to lung organoids to study respiratory viruses and testing therapeutics. | non-urgent |
Hello doctor, My fiancee and I had unprotected sex a few days back, but I did not ejaculate inside her. Just to be on the safer side, we wanted to use the emergency contraceptive pill. But due to some restriction in the country where we live, Plan B or emergency contraceptive pills are not available. I read that Yasmin, which is used as a regular contraceptive pill can be used as an emergency contraceptive pill at a higher dosage. Can Yasmin be used as an emergency contraceptive pill? And at what dosage? | non-urgent |
Q:An 18-year-old primigravid woman comes for her initial prenatal visit at 16 weeks' gestation. She is not sure about the date of her last menstrual period but says that the pregnancy probably occurred immediately after she stopped taking oral contraceptives 5 months ago. Maternal serum α-fetoprotein (MSAFP) concentration is increased to 3 multiples of the median. Which of the following is the most appropriate next step in management??
A:Repeat measurement of MSAFP concentration;B:Triple screening for MSAFP, serum β-hCG, and serum estriol concentrations;C:Ultrasonography;D:Amniocentesis for measurement of α-fetoprotein concentration | non-urgent |
Hi.....i got my periods on the 19th of November. I had unprotected sex on the 23rd of November and took postinor 2. A few days later i got my periods again.i had unprotected sex immediately after the bleeding. What are my chances of conceiving?. Thanks | non-urgent |
Who is at highest risk for Mesothelioma ? | non-urgent |
Hi. My son was in football practice and hit his nose to another players jaw. He was knocked out - saw black and woke up staring at the grass. He is complaining of a slight headache and a little dizzy, however his nose just stared bleeding again. Should I take him to the ER? | urgent |
What happens to the total resistance when a blood vessel is added to a system in series? | non-urgent |
Hello, I m inquiring about a mystery medical case. I think maybe if I research some it may help in some way...these are the symptoms my friend is experiencing: Roaring infection in her body, liver enzymes really high, fever of over103, dehydration , platelet cell counts very low, eyes and skin turned yellow, fluid around gall bladder enlarged spleen , iron level 3000. They said they can t find the source of the infection and right now all they could think of is that they suspect it could be the liver, hepatitis, gall bladder, Epstein barre, cmv , parvo or tick, and they may want to do a bone marrow test if not better soon...please help she s very young. ::(( | urgent |
Scan results, Uterus bulky with homogeneous myometrialechotenture no focal lesion noted, single regular intrauteine gessational sac with uniform decidual reaction noted yolk sac visualised and foetal pole with Google cardiac activity noted. CRL: 29mm 9w5d, LMP 9w1d | non-urgent |
Hi doctor, I am a 26 year old male. I am 5 feet and 9 inches tall and weigh 255 pounds. When I eat spicy food, I poop blood. Sometimes when I have constipation as well, I poop a little bit of blood. I am really scared that I have colon cancer. I do have diarrhea often. I do not have a family history of colon cancer. I got blood tests done last night. Please find my reports attached. | non-urgent |
Have you heard of parasites that can clog arteries? I have symptoms of a possible blocked artery (pain in left arm, in neck) and am going for some tests (echo, etc). However, I have been tested 6 months ago on standard tests and all were fine. I've been taking a parasite cleanse as a 2 were identified in a previous test. | urgent |
my right leg got affected with hyparesthesia after I had to take a bedrest for about 6 weeks,after I had undergone a femur-neck surgery due to an accident on my room floor for a hill skid. What is the indian allopathic remedy for a cure? In fact I cant stand or walk through the right leg as I experience severe pain form the right waist to the foot. | urgent |
Morning! I had the gastric sleeve sleeve done on August 6, 2012. I have also carry antigens hepatitis B for the last 16 years and the infection has not been active. My husband has been tested and was negative for the virus as well. I had bloodwork done and was told my liver enzymes was elevated. Any reasons why this could be? | non-urgent |
Digital technologies have the potential to empower individuals with autism and their families. The COVID-19 pandemic emphasized and accelerated the drive towards technology for information, communication, training, clinical care and research, also in the autism community. However, 95% of individuals with autism live in low- and middle-income countries (LMIC) where access to electricity, internet and the ever-increasing range of digital devices may be highly limited. The World Bank coined the term ‘the digital divide’ to describe the disparities in access to digital technologies between high-income and LMIC contexts. Here we evaluated the feasibility of six emerging technologies for autism spectrum disorders, and reflected on key considerations for implementation in LMIC contexts to ensure that we do not inadvertently widen the pre-existing digital divide. | non-urgent |
Dear sir,I am a married man for approx 1 year.i am finding some itchin in the edge of my penis. I can see some red dots at the tip and around it. every morning when I weak up i see some white covering over it. when i wash it clears, but it seems like the upper layer is going out. after washing I can see some red spots seems like scratches. its happening from last few weeks. I occassionaly do masterbution, but have never gone for sex with any kind of sex worker. i am little worried as it looks purple now and feels little itchy. I can see the red dots also. kindly suggest and guide. | non-urgent |
Hi. I have had a dry mouth with coated tongue for about a week. Had a yeast infection (oral about a month ago and used nystatin) . now have also red pustules (looks like acne, but I am sixty and female) erupting on my face. Is this another yeast infection or something else? | non-urgent |
What is the major risk factor for osteoarthritis and what are some additional risk factors? | non-urgent |
Sudden itchy bump on right hand while at work. Next day woke up with another bump right next to it. Over the course of a few days, new bumps will randomly appear on my arms, neck, lower back. And today, they have appesred on my shins. They are either single bumps, or maybe two or three in a straight line. Very tiny and clear. Once one bump goes away, it seems like a new bump appears elsewhere. No changes in diet, detergents, hygiene products, ect. Although we do use wood heat, but this has never been a problem before. Took cipro for uti a month ago. Currently take one 50mg tramadol a day(since 2008). I work at a hospital and was afraid i contacted scabies . Spoke with er doctor who said it is in no way scabies, but looks like some sort of bug bite or allegy. Was prescribed lindane , but will not use it! When these bumps appear, it is very sudden. With a sting/intense itch sensation. Itching will last a few moments, then fade for a few hours to days. No bed bugs or other insects that i am aware of are present. | non-urgent |
Hello Doctor, My husband is 63 yrs old ,and had started taking Krislow 100 mg alongwith some other medicines,beta blockers etc,as he was diagnosed with about 70% blockage in a couple of major arteries. in April this year.He is wondering if he should continue to take Krislow,as he has no symptoms otherwise and does not want to be over-medicated.He has already been put off 2 medicines...Atorvastatin,and Nicorandil. | non-urgent |
Hi. I had a chair thrown into me last night to my arm and it is now swollen, brushed & grazed. I have cleaned the graze with tap water and coated it in Germolene, it stops hurting when that is applied but without it, it starts to hurt. What is the best way to treat it? Thankyou. | non-urgent |
Female, African-American, 58 years old, recently diagnosed stage 2 diabetes, taking metformin 500mg / amitriptyline 10mg / lisinopril 12.5mg. Symptoms: tight band headache on forehead, cold chill with hot skin, extreme fatigue, diarrhea, unproductive deep cough, frequent urination, muscle ache, no appetite | urgent |
What is the recommended empirical antibiotic treatment for children suspected of having bacterial meningitis? | urgent |
I do not have a gallbladder but I am having pain in the middle of my breast bone in the lower area I also have burning in my throat all the way down my chest and I have vomit that keeps coming up in my throat but goes back down I never throw up completely and the pain can be unbearable at times | non-urgent |
I have been in cipro for 10 days. Told I had a kidney infection. My white blood cell count was at 12,000. They. are now back into the 6,000. My urine is clean. Ct scan showed no stones but I am still having left midnto lower back pain also some on right side. Had fever last night now is gone.my Dr. Continued my cipro for five more days. They can t figure out what this is. | non-urgent |
i have been having palpations daily, they are short, cause me stress and sometimes come with a sharp quick pain in the upper left chest. my ecg came back showing slighltly overworked but doctor was not concerned, should i be???? i am also prone to ocd and having anxiety over my health | non-urgent |
The article focuses on the legal aspects of surrogate motherhood and the factors that cause increasing attention to these issues. © 2021, Media Sphera Publishing Group. All rights reserved. | non-urgent |
Was told by a doctor after a slight changes in an ECG test following chest pains to call an ambulance if I experienced more chest pain. I did this last week, rushed to hospital but multiple ECGs and blood test all ok (doctor thought it was indigestion). Saw cardiologist two days later and she thought it might a blockage and is arranging a nuclear stress test but told me to ring 999 again if more pains. Pains returned, quite severe the following day so again went to hospital, stayed overnight. ECGs and blood test all ok, different cardiologist thinks it might be costochronitis (but wants me to still do the stress test). Seems unlikely to be an issue with my heart, but do I call an ambulance for a third time if it gets bad again? | urgent |
my son age 15 was diagnosed tuesday with IgA deficiency his level is <6 now a month ago it was <7...we were told he would not beable to have blood transfusion if he ever needed one..can he store his own blood in a blood bank or can he..what are the options for blood transfusion.. | urgent |
What is the effect of blockage of the mesocortical dopamine pathway on the symptoms of schizophrenia? | non-urgent |
To understand the dysfunctional mechanisms underlying maladaptive reasoning of psychosis, computational models of decision making have widely been applied over the past decade. Thereby, a particular focus has been on the degree to which beliefs are updated based on new evidence, expressed by the learning rate in computational models. Higher order beliefs about the stability of the environment can determine the attribution of meaningfulness to events that deviate from existing beliefs by interpreting these either as noise or as true systematic changes (volatility). Both, the inappropriate downplaying of important changes as noise (belief update too low) as well as the overly flexible adaptation to random events (belief update too high) were theoretically and empirically linked to symptoms of psychosis. Whereas models with fixed learning rates fail to adjust learning in reaction to dynamic changes, increasingly complex learning models have been adopted in samples with clinical and subclinical psychosis lately. These ranged from advanced reinforcement learning models, over fully Bayesian belief updating models to approximations of fully Bayesian models with hierarchical learning or change point detection algorithms. It remains difficult to draw comparisons across findings of learning alterations in psychosis modeled by different approaches e.g., the Hierarchical Gaussian Filter and change point detection. Therefore, this review aims to summarize and compare computational definitions and findings of dynamic belief updating without perceptual ambiguity in (sub)clinical psychosis across these different mathematical approaches. There was strong heterogeneity in tasks and samples. Overall, individuals with schizophrenia and delusion-proneness showed lower behavioral performance linked to failed differentiation between uninformative noise and environmental change. This was indicated by increased belief updating and an overestimation of volatility, which was associated with cognitive deficits. Correlational evidence for computational mechanisms and positive symptoms is still sparse and might diverge from the group finding of instable beliefs. Based on the reviewed studies, we highlight some aspects to be considered to advance the field with regard to task design, modeling approach, and inclusion of participants across the psychosis spectrum. Taken together, our review shows that computational psychiatry offers powerful tools to advance our mechanistic insights into the cognitive anatomy of psychotic experiences. | non-urgent |
COVID-19 has caused a shortage of healthcare workers and has strained healthcare systems globally. Pre-registered healthcare students with training have a duty of care and can support the healthcare workforce. This study explored factors influencing the willingness of final-year nursing students to volunteer during the COVID-19 pandemic, the role of professional identity in volunteering as healthcare workers, and strategies to improve future volunteering uptakes and processes. A qualitative study using focus-group discussions was conducted. Final-year nursing students who volunteered, students who did not volunteer, and lecturers who supervised student volunteers were recruited. Interviews were conducted online, video-recorded, and transcribed verbatim. A thematic analysis was used. The themes were "wavering thoughts on volunteering", "bringing out 'the nurse' in students through volunteering" and "gearing up to volunteer". Findings suggested the need to look beyond the simplicity of altruism to the role of professional identity, operational, and motivational factors to explain nursing students' decision to volunteer and their volunteer behavior. Providing accommodation, monetary and academic-related incentives, supporting the transitionary phase from students to "professional volunteers", promoting cohesive and positive staff-student volunteer relationships, and establishing a volunteer management team are strategies identified to improve volunteering uptake and operational processes. Our findings advocate strategic partnerships between hospitals/communities and academic institutions in providing various healthcare services during pandemics. | non-urgent |
I have numbness in my legs, that has migrated from my arms. I have been to a number of doctors and none of them, not one, has launched an investigation into my symptoms. Is there a reason for this? It s a much longer story, but this is the short version | non-urgent |
I am suffering from Gout as per Doctor's investigation. My uric acid level lie between 5.0 to 5.5. I am on Zyloric medication. there are hardenig of vein on foot region (above ankle & below knee) & on toe ,knee area with swelling & acute pain. This things are happen when high proein diet taken. What shall i do? | non-urgent |
I AM 45 y.o. and suffering from severe back pain.MRI shows I have diffuse disc bulging L3/L4 to L5/S1 w/ posterior annular tear at L4/L5 level. and also mild dextroscoliosis dorsal spine.DO I really need to undergo an operation to correct it? THANK YOU. | non-urgent |
What type of disorder is Factor V Leiden and what is the underlying cause of thrombosis in this disorder? | non-urgent |
pain with every deep breath -sharp, painful. also a cough started over last week. i fell down a flight of stairs on my back3 weeks ago. had back x-ray no breaks or fractures. i dont understand this new pain 2 weeks after the fall or the sudden cough. could my lungs be bruised or something else? | urgent |
What is the typical initial manifestation of Kaposi sarcoma? | non-urgent |
What are the initial steps recommended for managing Ménière disease? | non-urgent |
Our findings seem suggest that improving muscular fitness as well as an adherence to the SEADiet could be an important strategy to reduce clustered cardiometabolic risk in youth. | non-urgent |
What causes Yaws? | non-urgent |
OBJECTIVES: To document lessons from the Global Polio Eradication Initiative (GPEI) by determining factors associated with successful surveillance programme globally as well as at national and subnational levels. The process of conducting surveillance has been previously recognised in the literature as important for the success of polio surveillance activities. DESIGN: A cross-sectional survey with closed and open-ended questions. SETTINGS: Survey of persons involved in the implementation of surveillance activities under the GPEI at the global level and in seven low-income and middle-income countries. PARTICIPANTS: Individuals (n=802) with ≥12 months of experience implementing surveillance objective of the GPEI between 1988 and 2019. MAIN OUTCOME MEASURES AND METHODS: Quantitative and qualitative analyses were conducted. Logistic regression analyses were used to assess factors associated with implementation process as a factor for successful surveillance programme. Horizontal analysis was used to analyse qualitative free-text responses on facilitators and barriers identified for conducting surveillance activities successfully. RESULTS: Overall, participants who reported challenges relating to GPEI programme characteristics had 50% lower odds of reporting implementation process as a factor for successful surveillance (adjusted OR (AOR): 0.50, 95% CI: 0.29 to 0.85). Challenges were mainly perceptions of external intervention source (ie, surveillance perceived as ‘foreign’ to local communities) and the complexity of surveillance processes (ie, surveillance required several intricate steps). Those who reported organisational challenges were almost two times more likely to report implementation process as a factor for successful surveillance (AOR: 1.89, 95% CI: 1.07 to 3.31) overall, and over threefolds (AOR: 3.32, 95% CI: 1.14 to 9.66) at the national level. CONCLUSIONS: Programme characteristics may have impeded the process of conducting surveillance under the GPEI, while organisational characteristics may have facilitated the process. Future surveillance programmes should be designed with inputs from local communities and frontline implementers. | non-urgent |
Hello, I have penis problem. When my penis is getting hard, to erection, some liquid drop from it and it`s just transparent. different from white sperms. Especially it drops when my penis is getting to be soft, back to flaccid state. Is it normal or do I have any problems? Thanks for your attention. | non-urgent |
my daughter three an a half month old,before 16 days(1st feb) she has start grennish watery stool at 7-8 times a day,than my ped says to give sporlac to her but not stopped.than they started enterogermina & zinc powder& pedialite for 3 days.but stool consistency nigther change nor colour.after that stool test done & on report pus cell 35-40 are found.than we deside to change ped, than new ped give to her tufpro,collostine,vitazyme..then i see change in stool its consistency semi solid,mild yellow colour.but again after 2 day she has started watery greenish stool with frothy and smelling.again we call to our new ped than he chang medicine & give zifi,neopeptine, bifilac,zocon 50,vitazyme.& dr says if no changes r seen so he started soya milk/rice preparation. sir its all running last 2 days but colour is grenish and frothy stool pass out again & again.i cant understand what is running please help. and another prob is my baby has due vaccine for 14 wk all +rota g &pnumococal also.due date is 13 feb,but due to her sickness we not go. sir how many days we can delay vaccine. plz help | non-urgent |
Hello,I believe that my son has been using meth-amphetamine for approx 6 months now,and i would like to take him in for a drug test. I have not yet decided whetherto get a hair, urine or blood test, but because he is legally responsible, imust have his consent to test him, therefore, i am wondering if there is anywayhe could cheat the test that i should watch for, or how soon i should get itdone. I have inquired about this with a couple physicians, and they have eachtold me different opinions, but i would also like to know how long it wouldtakehim to clean his system before the test. he is 5'10, about 125lbs, hashypoglycemia, is highly active with a high metabolism, and is 18yrs old. ThankyouConcerned Parent | urgent |
I have a hard dime sized bump in the crease of my leg near my pelvic area. It doesn t hurt and doesn t seem irritated. I ve never had this before and am a little freaked out. I do however have cysts along my jaw line and was wondering if it could possibly be the same thing? | non-urgent |
I have been experiencing a bad cough and rhinitis. My latest symptoms today is a sharp pain in my upper ribs front side of my body. Hard to breath in deeply. Was at doctor last week no pneumonia lung were clear. I saw something on pleurisy? Not sure 54 yr old female. Thanks mtrudy3742jc@yahoocom | non-urgent |
26 month grandchild unab;e to put right leg on floor. Unable to walk for 3 hours this morning but is now running around 4 times since leg gave away for a few seconds. Brought him to hospital no pain allingment is normal xray are all normal Any ideas This all started about 16 months ago | non-urgent |
My son has a removable brace on his top teeth which he has to enlarge twice a week. His gums are looking very slightly inflamed but th today he pointed out a flap of skin between two teeth which are being moved. Is this a normal part of teeth movement or do I need to take him to the orthodontist to get it checked | non-urgent |
I had a a small lump that felt like a hard pea, I squeezed it a couple of times and notice it got larger and more tender to touch, I began to apply heat to the area which is on my right lower side above the buttock for about 2 weeks and today when I squeezed it a watery/pus come from the area. do you think I need to see a doctor, it is still a little tender and still a little hard when I squeeze this area to help it drain more. thank you for your answer. | urgent |
Hello Sir, I am 28 years old married guy and below are the particulars of my sperm test report. Please have a look into this and interpret the results to me.. I am concerned whether I am sexually normal or do I need to consult a doctor for a baby. Volume: 0.5 ml Viscosity: Thin Reaction: Alkaline Sperm Count: 65 million/ml Active Motile: 60% Sluggish: 10% Non Motile: 30% Epithelial Cells: NIL Pus Cells: 2-3/HPF Erythrocytes: 0-1/HPF Morphology Normal: 80% Abnormal: 20% Others: NIL I am waiting for a quick reply. Thanks in advance for your support. | non-urgent |