Newsgroup: it.scienza.biologia
Titolo: Acqua idrogenata = elisir di lunga vita?

 dai miei ricordi. Non mi appassionava pi� di tanto :-\
Perch� non ti vendichi sostituendo gli antiossidanti inefficaci
e quelli pericolosi (in quanto distruttivi dell'ossido nitrico)
con il banalissimo e inorganico (di)idrogeno H2 ? Guarda qua:
 
http://www.ncbi.nlm.nih.gov/pubmed?term=hydrogen%20Ohta%20S
Qui di seguito ne riporto una dozzina di titoli (completati da un paio
di abstract e due articoli di cui si pu� scaricare gratis il full text):
  1. Hydrogen Therapy Attenuates Irradiation-induced Lung Damage
     by Reducing Oxidative Stress.  (2011)
  2. Recent Progress Toward Hydrogen Medicine: Potential of Molecular
     Hydrogen for Preventive and Therapeutic Applications.
   Abstract: Persistent oxidative stress is one of the major causes
   of most lifestyle-related diseases, cancer and the aging process.
   Acute oxidative stress directly causes serious damage to tissues.
   Despite the clinical importance of oxidative damage, antioxidants
   have been of limited therapeutic success. We have proposed that
   molecular hydrogen (H(2)) has potential as a "novel" antioxidant
   in preventive and therapeutic applications [Ohsawa et al., Nat Med.
   2007: 13; 688-94]. H(2) has a number of advantages as a potential
   antioxidant: H(2) rapidly diffuses into tissues and cells, and
   it is mild enough neither to disturb metabolic redox reactions
   nor to affect reactive oxygen species (ROS) that function in cell
   signaling, thereby, there should be little adverse effects of
   consuming H(2). There are several methods to ingest or consume H(2),
   including inhaling hydrogen gas, drinking H(2)-dissolved water
   (hydrogen water), taking a hydrogen bath, injecting H(2)-dissolved
   saline (hydrogen saline), dropping hydrogen saline onto the eye,
   and increasing the production of intestinal H(2) by bacteria. Since
   the publication of the first H(2) paper in Nature Medicine in 2007,
   the biological effects of H(2) have been confirmed by the publication
   on more than 38 diseases, physiological states and clinical tests
   in leading biological/medical journals, and several groups have
   started clinical examinations. Moreover, H(2) shows not only effects
   against oxidative stress, but also various anti-inflammatory and
   anti-allergic effects. H(2) regulates various gene expressions and
   protein-phosphorylations, though the molecular mechanisms underlying
   the marked effects of very small amounts of H(2) remain elusive.
  3. Molecular hydrogen is a novel antioxidant to efficiently reduce
     oxidative stress with potential for the improvement of
     mitochondrial diseases.
  5. Molecular Hydrogen Improves Obesity and Diabetes by Inducing
     Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice.
  6. Protection of the retina by rapid diffusion of hydrogen:
     administration of hydrogen-loaded eye drops in retinal
     ischemia-reperfusion injury.  (2010)
   Free article: 
http://www.iovs.org/content/51/1/487.full.pdf
  7. Are the effects of alpha-glucosidase inhibitors on cardiovascular
     events related to elevated levels of hydrogen gas in the
     gastrointestinal tract?  (2009)
  8. Molecular hydrogen is protective against 6-hydroxydopamine-induced
     nigrostriatal degeneration in a rat model of Parkinson's disease.
 10. Molecular hydrogen alleviates nephrotoxicity induced by an
     anti-cancer drug cisplatin without compromising anti-tumor
     activity in mice.
 11. Consumption of hydrogen water prevents atherosclerosis
     in apolipoprotein E knockout mice.  (2008)
 14. Consumption of molecular hydrogen prevents the stress-induced
     impairments in hippocampus-dependent learning tasks during
     chronic physical restraint in mice.
   Free article: 
www.nature.com/npp/journal/v34/n2/pdf/npp200895a.pdf
 15. Inhalation of hydrogen gas reduces infarct size in the rat model
     of myocardial ischemia-reperfusion injury.
 17. Hydrogen acts as a therapeutic antioxidant by selectively
     reducing cytotoxic oxygen radicals.  (2007)
   Abstract: Acute oxidative stress induced by ischemia-reperfusion
   or inflammation causes serious damage to tissues, and persistent
   oxidative stress is accepted as one of the causes of many common
   diseases including cancer. We show here that hydrogen (H(2))
   has potential as an antioxidant in preventive and therapeutic
   applications. We induced acute oxidative stress in cultured cells
   by three independent methods. H(2) selectively reduced the hydroxyl
   radical, the most cytotoxic of reactive oxygen species (ROS), and
   effectively protected cells; however, H(2) did not react with other
   ROS, which possess physiological roles. We used an acute rat model
   in which oxidative stress damage was induced in the brain by focal
   ischemia and reperfusion. The inhalation of H(2) gas markedly
   suppressed brain injury by buffering the effects of oxidative stress.
   Thus H(2) can be used as an effective antioxidant therapy; owing to
   its ability to rapidly diffuse across membranes, it can reach and
   react with cytotoxic ROS and thus protect against oxidative damage.
Bye,
  *GB* 

 con il banalissimo e inorganico (di)idrogeno H2 ? Guarda qua:
non ho capito la intro ... ma veramente interessante. 
L'avrei detto un gas inerte e non assorbito. A volte siamo 
ingenui :)
Appena ho tempo mi leggo qualcosa
ciao
Soviet
CUT ALL

 A volte siamo ingenui :)
Le cose troppo semplici possono anche essere le pi� difficili da pensare.
Bye,
  *GB*