Newsgroup: it.economia.borsa
Titolo: Cell Therapeutics says Xyotax has future

Cell Therapeutics says Xyotax has future
Tue Feb 21, 2006 5:07 PM ET
By Deena BeasleyLOS ANGELES (Reuters) -
Cell Therapeutics Inc. <CTIC.O>, whose experimental lung cancer drug Xyotax
failed in two key clinical trials, still sees promise for the drug and
expects to file for U.S. regulatory approval in the fourth quarter of this
year, the company's chief executive said on Tuesday.
While Cell Therapeutics failed to show that Xyotax was superior to standard
chemotherapy, the company did find a survival benefit in women taking the
drug and has launched a separate trial to test its effectiveness.
CEO James Bianco said at the Reuters Biotechnology Summit in Los Angeles
that the company will begin submitting Xyotax data to the U.S. Food and Drug
Administration in the fourth quarter of this year and hopes to have a
decision from the agency by the second quarter of next year, based on the
previous studies and interim results from the latest trial focused on women.
"Our goal is to take data from interim analysis and feed it into the new
drug application in the fourth quarter of this year, which will be based on
observations made in the two (earlier late-stage) studies," Bianco said.
The CEO said the company expects to meet with high-level FDA officials in
the second quarter of this year to finalize the filing strategy.
Under the best-case scenario, Cell Therapeutics would be able to launch
Xyotax in the fourth quarter of 2007, he said.
If the company has to wait until the latest trial is complete, the
regulatory filing would happen in 2008, Bianco said.
Xyotax links the chemotherapy drug paclitaxel to a substance that binds to
tumors, with the goal of reducing damage to healthy cells as well as side
effects like nausea and hair loss.
The drug is believed to work better in women because enzymes regulated by
the hormone estrogen break down the protein binding, enhancing effectiveness
of the treatment.
"The data in women deserves its day in front of the FDA," Bianco said.
He said a few multinational pharmaceutical companies have been particularly
interested in the drug's gender-specific effect and the company hopes to
sign up a commercial partner.
In order to do that, Cell Therapeutics would like to regain rights to the
drug in Japan and other Asian countries that are now held by Chugai
Pharmaceutical Co. Ltd. <4519.T>.
Such an announcement is likely "within the next few weeks," Bianco said.


e' questa ultima parte che fara skizzare il titolo dopo la primavera io ne
ho in cassa 20.000 a 1.65? e le tengo fino a dicembre poi ne riparleremo
;o)..

 ;o)..
la parte più interessante è indubbiamente l'ultima
e questo solo per lo Xyotax ( più vicina è la registrazione in Europa)

 ha scritto nel messaggio 
news:43fc2adc$0$5990$4faf...@reader2.news.tin.it...

Però mi sorge un dubbio, possibile che quelli che non le hanno siano tutti 
fessi?
Non che io abbia una grande opinione dei gestori del risparmio italiani, ma 
quelli americani saranno mica fessi come gli italiani?
Saluti dubbiosi. 

 Saluti dubbiosi.
č un titolo sottile
ci sono in giro poche azioni
 č adatto per pochi istituzionali


gli istituzionali non lo hanno in portafoglio
(chiedi se a me non credi) 

  è adatto per pochi istituzionali
UAHUHAUHAUA sottile... pochi istituzionali...
Shares Outstanding: 71.85M
Float: 68.82M
% Held by Insiders4: 20.64%
% Held by Institutions4: 35.90%
Shares Short (as of 10-Jan-06)3: 8.27M
Short Ratio (as of 10-Jan-06)3: 15.7
Short % of Float (as of 10-Jan-06)3: 12.40%
Shares Short (prior month)3: 9.74M
AHAHAHHAHAHAHAHAH
AHAHAHAA
AHAHAHAAHAHAHA
HAHAH
AHA
AHAH
AHAH
AHAHAH
AAHHA
AA
HAAH
AHA

 
Come quelle  a 2 che tenevi fino ad agosto dell'anno scorso?
Bello sto titolo!
MUAH UHA UHA UHA UHA UHA 


              Institutional Holdings  Description | Show Summary
            Owner Name
            Select a name below for more information.  Date  Shares Held
Change
            (Shares)  % Change
            (Shares)  Value
            ($1000)
            STATE STREET CORP  12/31/2005  723,559  54,142  8.09%  $1,404
            MORGAN STANLEY  12/31/2005  697,073  322,053  85.88%  $1,352
            NORTHERN TRUST CORP  12/31/2005  531,782  20,925  4.10%  $1,032
            CITADEL L P  12/31/2005  517,165  29,239  5.99%  $1,003
            TIAA CREF INVESTMENT...  12/31/2005  506,318  70,272  16.12%
$982
            SEEMORE ADVISORS LLC  12/31/2005  300,000  0  0.00%  $582
            MELLON FINANCIAL COR...  12/31/2005  286,235  13,900  5.10%
$555
            SHAW D E & CO INC  12/31/2005  248,249  24,350  10.88%  $482
            BARCLAYS PLC  12/31/2005  206,852  -  -  $401
            JANE STREET HOLDING,...  12/31/2005  196,494  (441,639)
(69.21%)  $381
            CALIFORNIA PUBLIC EM...  12/31/2005  173,900  0  0.00%  $337
            MERRILL LYNCH ASSET ...  12/31/2005  140,836  9,900  7.56%  $273
            AMVESCAP PLC/LONDON/  12/31/2005  129,112  0  0.00%  $250
            PUBLIC EMPLOYEES RET...  12/31/2005  116,912  12,278  11.73%
$227
            CREDIT SUISSE ASSET ...  12/31/2005  110,498  0  0.00%  $214
            FUND ASSET MANAGEMEN...  12/31/2005  91,937  (15,400)  (14.35%)
$178
            STATE BOARD OF ADMIN...  12/31/2005  89,612  0  0.00%  $174
            WITTER WILLIAM D INC  12/31/2005  87,200  0  0.00%  $169
            BEAR STEARNS & CO IN...  12/31/2005  84,940  (700)  (0.82%)
$165
            GOLDMAN SACHS GROUP ...  12/31/2005  82,036  11,760  16.73%
$159
      Select a name below for more information.  Date  Shares Held   Change
      (Shares)  % Change
      (Shares)  Value
      ($1000)
      STICHTING PENSIOENFO...  12/31/2005  64,700  64,700  New  $126
      CREDIT SUISSE  12/31/2005  61,710  8,400  15.76%  $120
      UBS AG  12/31/2005  60,762  (30,903)  (33.71%)  $118
      ATTICUS MANAGEMENT L...  12/31/2005  50,000  (100,000)  (66.67%)  $97
      CREDIT SUISSE/  12/31/2005  49,666  28,062  129.89%  $96
      AMERICAN INTERNATION...  12/31/2005  49,001  2,235  4.78%  $95
      LEHMAN BROTHERS HOLD...  12/31/2005  48,122  48,122  New  $93
      DEUTSCHE BANK AG\  12/31/2005  42,159  (1,391)  (3.19%)  $82
      TEACHERS ADVISORS IN...  12/31/2005  36,178  1,200  3.43%  $70
      MILLENNIUM MANAGEMEN...  12/31/2005  32,740  (134,545)  (80.43%)  $64
      GEODE CAPITAL MANAGE...  12/31/2005  31,761  0  0.00%  $62
      PUBLIC EMPLOYEES RET...  12/31/2005  25,500  0  0.00%  $49
      SG AMERICAS SECURITI...  12/31/2005  25,175  (7,257)  (22.38%)  $49
      HOFFMAN GABE  12/31/2005  24,340  -  -  $47
      CITIGROUP INC  12/31/2005  21,580  (62,496)  (74.33%)  $42
      MFC GLOBAL INVESTMEN...  12/31/2005  20,602  2,463  13.58%  $40
      PROFUND ADVISORS LLC  12/31/2005  20,192  3,440  20.53%  $39
      MUNDER CAPITAL MANAG...  12/31/2005  19,731  1,226  6.63%  $38
      AXA  12/31/2005  19,661  (6,000)  (23.38%)  $38
      BANK OF AMERICA CORP...  12/31/2005  15,500  0  0.00%  $30
      Select a name below for more information.  Date  Shares Held   Change
      (Shares)  % Change
      (Shares)  Value
      ($1000)
      US BANCORP \DE\  12/31/2005  14,189  150  1.07%  $28
      RHUMBLINE ADVISERS  12/31/2005  12,995  12,995  New  $25
      DRESDNER BANK AG /FI  12/31/2005  12,000  (26,000)  (68.42%)  $23
      SCHRODER INVESTMENT ...  12/31/2005  11,500  0  0.00%  $22
      PRICE T ROWE ASSOCIA...  12/31/2005  10,400  0  0.00%  $20
      BANK OF NEW YORK /NY...  12/31/2005  7,015  3,200  83.88%  $14
      QUANTLAB CAPITAL MAN...  12/31/2005  5,408  5,408  New  $10
      RBC DAIN RAUSCHER IN...  12/31/2005  5,000  0  0.00%  $10
      WELLS FARGO & CO/MN  12/31/2005  2,440  1,500  159.57%  $5
      MERRILL LYNCH & CO I...  12/31/2005  1,580  (162,446)  (99.04%)  $3
      SCHWAB CHARLES INVES...  12/31/2005  1,400  0  0.00%  $3
      TD ASSET MANAGEMENT ...  12/31/2005  1,350  0  0.00%  $3
      UNIONBANCAL CORP  12/31/2005  1,000  1,000  New  $2
      DAVIDSON D A & CO  12/31/2005  500  500  New  $1
      LOS ANGELES CAPITAL ...  12/31/2005  500  0  0.00%  $1
      PUTNAM INVESTMENT MA...  12/31/2005  400  0  0.00%  $1
      TRUST CO OF VERMONT  12/31/2005  100  0  0.00%  $0
      TORONTO DOMINION BAN...  12/31/2005  0  (35)  Sold Out  $0
      LEGG MASON INC  12/31/2005  0  (600)  Sold Out  $0
      PADCO ADVISORS II IN...  12/31/2005  0  (9,087)  Sold Out  $0

io parlavo di Italia......

 ha scritto nel messaggio 
news:43fc4f2c$0$5988$4faf...@reader2.news.tin.it...


> io parlavo di Italia......
saranno sotto il 2% e quindi non segnalati

 io parlavo di Italia...... 

 -- 
evidentemente stai dicendo una cazzata. 


hai letto? 

 presenti....
io parlavo di Italia infatti

 saranno sotto il 2% e quindi non segnalati
e state certi che prima dei risultati saliranno ben sopra il 2% (e non è 
escluso che piano piano lo stiao già facendo in silenzio... e quando lo 
avranno segnalato sarù già tardi)

in America l'associazione Donne contro il cancro, WALC, con le Dott. sse
SCHILLER ed ALBAIN, ha  inviato una petizione anche al Presidente BUSH.
sperano anche loro nello Xyotax
http://www.womenagainstlungcancer.org/
Dear Mr. President, Senators and Representatives:
It is a little known and much ignored fact that LUNG CANCER kills more women
in the United States of America each year than any other cancer. Over
160,000 Americans will die this year from lung cancer and nearly 70,000 of
those will be our mothers, sisters and daughters. To put this in
perspective, lung cancer will be responsible for more deaths than breast
cancer, ovarian cancer, and uterine cancer combined.
Women Against Lung Cancer is a unique non-profit organization of leading
scientists, physicians, nurses and advocates dedicated to DECREASING DEATHS
DUE TO LUNG CANCER, AND HELPING PATIENTS LIVE LONGER AND BETTER, THROUGH
RESEARCH, AWARENESS AND ADVOCACY. As our country's representatives and
leaders, we need your help to increase awareness of, improve education
about, and support research funding for this disease. A marked increase in
research funding specifically for LUNG CANCER is urgently needed. As you
know, improvements in survival will only come through increased research. We
believe that an up-front investment of research dollars is critical to raise
awareness and increase research efforts to at least the level of achievement
currently being expended on other common types of cancer.
Signed,
Women Against Lung Cancer and the People of America whose lives have been
changed forever by LUNG CANCER