text stringlengths 0 197k |
|---|
* undergo either traditional or orthodontic extraction |
* be monitored for postoperative paresthesia. |
Researchers will compare traditional and orthodontic extraction methods to see if extraction methods affect postoperative nerve damage. conditions: Inferior Alveolar Nerve Injuries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked... |
<|newrecord|> nctId: NCT06270771 id: 5823 briefTitle: OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study acronym: OURA MDS overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-08-01 date: 2026-02-01 date: 2024-02-21 date: 2024-02-21 name: Sunnybrook Health Sciences Centre class... |
<|newrecord|> nctId: NCT06270758 id: 453/2023/Sper/IOR briefTitle: Clinical Validation of BBCT-hip acronym: ValidaBBCT-hip overallStatus: RECRUITING date: 2023-11-07 date: 2030-11-06 date: 2030-11-06 date: 2024-02-21 date: 2024-02-21 name: Istituto Ortopedico Rizzoli class: OTHER briefSummary: The clinical study is aim... |
<|newrecord|> nctId: NCT06270745 id: sdycllyy001 briefTitle: ICG Anastomotic Control in Digestive System Surgery overallStatus: RECRUITING date: 2018-01-01 date: 2024-02-01 date: 2024-06-01 date: 2024-02-21 date: 2024-02-23 name: Shandong Linglong Yingcheng Hospital class: NETWORK briefSummary: This was a parallel sing... |
<|newrecord|> nctId: NCT06270732 id: PID2021-125444OB-100-II-iM briefTitle: Efficacy of iMentalize and MISC-SA to Foster Parents' Mentalization and Children Mental Health in General Population. acronym: iMentalize overallStatus: RECRUITING date: 2024-02-05 date: 2025-02-21 date: 2025-03-03 date: 2024-02-21 date: 2024-0... |
PARTICIPANTS will randomly receive one of the 3 interventions, all based in 30 weekly online non-synchronic sessions extended across 1 year: the iMentalize program (based on parent-child sessions where they see and talk about cartoon shorts), the MISC-SA (self-administered MISC version based on guided video-feedback us... |
COMPARISONS: Researchers will compare all 3 groups among them to see to what extent: |
* iMentalize program shows efficacy in fostering mentalization compared with MISC-SA and TAU (control group). |
* iMentalize program shows efficacy in fostering children's mental health compared with TAU (control group). |
* MISC-SA shows efficacy in fostering parent's mentalization and children mental health compared with TAU (control group). conditions: Emotional Intelligence conditions: Social Interaction conditions: Mental Health Wellness 1 conditions: Well-Being, Psychological studyType: INTERVENTIONAL phases: NA allocation: RANDOMI... |
<|newrecord|> nctId: NCT06270719 id: SRP-9001-401 briefTitle: An Observational Study Comparing Delandistrogene Moxeparvovec With Standard of Care in Participants With Duchenne Muscular Dystrophy acronym: ENDURE overallStatus: RECRUITING date: 2024-02-07 date: 2029-12-31 date: 2038-12-31 date: 2024-02-21 date: 2024-04-1... |
<|newrecord|> nctId: NCT06270706 id: PLN-101095-ONC-101 briefTitle: A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors overallStatus: RECRUITING date: 2023-08-30 date: 2025-06 date: 2025-12 date: 2024-02-21 date: 2024-02-21 name: Pliant Therapeutics, Inc. class: INDUSTRY briefSummary: This... |
The study will consist of 2 main parts: |
* Part 1: Consecutive dose-escalation cohorts using a Bayesian optimal interval (BOIN) dose escalation design |
* Part 2: Dose-expansion cohorts using Simon's 2-stage design conditions: Metastatic Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 77 type: ESTIMATED name: PLN-101095 name: Pembrolizumab measure: Proportion of... |
<|newrecord|> nctId: NCT06270693 id: Dr Sushma briefTitle: hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical Periodontitis overallStatus: ACTIVE_NOT_RECRUITING date: 2022-11-01 date: 2024-02-01 date: 2024-04-01 date: 2024-02-21 date: 2024-02-21 name: Postgraduate Institute of Dental Sc... |
<|newrecord|> nctId: NCT06270680 id: STUDY00023019 briefTitle: Carotenoids for Collision Athletes overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2024-12-20 date: 2024-12-20 date: 2024-02-21 date: 2024-03-18 name: Penn State University class: OTHER name: MacuHealth name: Orlando Regional Medical Center briefSu... |
<|newrecord|> nctId: NCT06270667 id: LYMfit briefTitle: Effects of Exercise Training in Survivors of Lymphoma acronym: LYMfit overallStatus: RECRUITING date: 2024-03-20 date: 2028-09-01 date: 2028-09-01 date: 2024-02-21 date: 2024-03-22 name: Norwegian School of Sport Sciences class: OTHER name: Uppsala University brie... |
<|newrecord|> nctId: NCT06270654 id: 2023322-12280 briefTitle: Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery overallStatus: RECRUITING date: 2023-06-01 date: 2024-05-01 date: 2024-06-01 date: 2024-02-21 date: 2024-02-21 name: University of Malaya class: OTHER brief... |
<|newrecord|> nctId: NCT06270641 id: STUDY00018628 briefTitle: Increasing Physical Activity for Adults With Multiple Sclerosis (MS) overallStatus: RECRUITING date: 2024-02-16 date: 2025-04-30 date: 2026-09-30 date: 2024-02-21 date: 2024-02-22 name: University of Washington class: OTHER briefSummary: This study aims to ... |
<|newrecord|> nctId: NCT06270628 id: NL85029.018.23 briefTitle: Personalized Live-remote Exercise Training for Cancer Survivors acronym: LION overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2026-10-31 date: 2027-10-31 date: 2024-02-21 date: 2024-02-21 name: UMC Utrecht class: OTHER name: German Cancer Research... |
Many people with cancer face ongoing problems from their disease and treatments, like fatigue, reduced physical fitness, feeling anxious or down, and neuropathy. While exercise might help with these problems, most studies did not focus on tailoring exercise to address these specific complaints. Exercise programs under ... |
Goal of the study: |
The main goal of this study is to assess the effectiveness of a personalized, live-remote exercise intervention for cancer survivors on quality of life and the patients' main complaint. The four complaints tackled in this study are: 1) fatigue, 2) reduced physical functioning, 3) anxiety and/or depressive symptoms, and... |
Design of the study |
In the LION study, 350 cancer patients will be randomly divided into the exercise group or control group. These patients all have at least one of these complaints: 1) fatigue, 2) reduced physical functioning, 3) anxiety and/or depressive symptoms, and/or 4) neuropathy. Patients cannot participate in the study if they a... |
The exercise group will start a 12-week exercise program right away, and the other group will wait for 12 weeks before starting. The exercise program consists of three sessions per week. Two sessions per week include aerobic training and strength training. These sessions will be followed by all patients; and aim to imp... |
Participants will get an app and a fitness tracker to help them stay on track with their exercises. Furthermore, patients get information on the effects of exercise for cancer patients and why exercise is important for specific complaints. |
Measurements |
The main outcomes of this study are quality of life and the main side-effect of the patient. Other measurements include all kind of patient reported outcomes (like sleep problems and pain), physical fitness, muscle strength, balance, anthropometrics, and (inflammatory) markers in blood. |
Conclusion: |
This study investigates if personalized exercises done at home, with video guidance, can make cancer survivors feel better and manage their side effects more effectively. conditions: Neoplasms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: RCT with ... |
<|newrecord|> nctId: NCT06270615 id: CRCBDD1712 briefTitle: Prospective Validation of the SHOCKMATRIX Hemorrhage Predictive Model acronym: SHOCKMATRIX overallStatus: RECRUITING date: 2022-07-01 date: 2024-06 date: 2024-06 date: 2024-02-21 date: 2024-02-21 name: Assistance Publique - Hôpitaux de Paris class: OTHER name:... |
<|newrecord|> nctId: NCT06270602 id: ONCOCAMP id: 6/23 oss type: OTHER domain: IRCCS I.N.T. "G. Pascale" briefTitle: The ONCOCAMP Study overallStatus: RECRUITING date: 2023-07-14 date: 2024-07 date: 2026-07 date: 2024-02-21 date: 2024-02-21 name: National Cancer Institute, Naples class: OTHER briefSummary: The present ... |
<|newrecord|> nctId: NCT06270589 id: IRB-2023-1684 briefTitle: Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-05 date: 2026-05 date: 2024-02-21 date: 2024-02-21 name: Purdue University class: ... |
Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest |
Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest |
Participants will visit the laboratory on 5 separate days (\> 2-day washout between days) in which they have not previously participated in structured physical activities. |
Participants will complete the testing and/or receive treatments below: |
Day 1: |
* Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient |
* Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption) |
Days 2-5 |
* Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting) |
* Participants' heart rate and self-reported affect and rating of physical exertion will be measured |
* Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility |
* Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance |
Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF. |
Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: NA allocation: RA... |
<|newrecord|> nctId: NCT06270576 id: HS3131 briefTitle: Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma acronym: Nasal-LPS overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-04 date: 2028-06 date: 2024-02-21 date: 2024-02-21 name: National Jewish Health class: OTHER briefSummary: A phas... |
<|newrecord|> nctId: NCT06270563 id: P.T.REC/012/003967 briefTitle: High Intensity Laser Therapy Versus Scapular Stabilization Exercises on Ventilatory Function in Forward Head Posture overallStatus: COMPLETED date: 2022-10-01 date: 2023-12-01 date: 2023-12-01 date: 2024-02-21 date: 2024-02-21 name: Cairo University cl... |
<|newrecord|> nctId: NCT06270550 id: DMI in Spastic Diplegia briefTitle: Role of Dynamic Movement Intervention in Children With Spastic Diplegia overallStatus: RECRUITING date: 2024-03-01 date: 2024-11-01 date: 2024-12-01 date: 2024-02-21 date: 2024-02-21 name: Cairo University class: OTHER briefSummary: The study aims... |
<|newrecord|> nctId: NCT06270537 id: Dominus PMCF briefTitle: Post-market Clinical Trial of the Dominus® Stent-Graft acronym: DominusPMCF overallStatus: RECRUITING date: 2023-10-24 date: 2025-07-30 date: 2029-02-28 date: 2024-02-21 date: 2024-02-21 name: Braile Biomedica Ind. Com. e Repr. Ltda. class: INDUSTRY briefSum... |
<|newrecord|> nctId: NCT06270524 id: RCAPHM21_0433 briefTitle: Study of the C5a/C5aR1 Axis in IgG4-associated Disease: a Potential Therapeutic Target acronym: C5-MAG4 overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-12-31 date: 2024-02-21 date: 2024-02-21 name: Assistance Publique Hopitaux... |
<|newrecord|> nctId: NCT06270511 id: 2222T1412 briefTitle: A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants overallStatus: RECRUITING date: 2024-03-13 date: 2024-05-31 date: 2024-06-19 date: 2024-02-21 date: 2024-03-19 name: Shionogi class: INDUSTRY briefSummary: The aim of this s... |
<|newrecord|> nctId: NCT06270498 id: 24811 briefTitle: Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure acronym: RISE-HF overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-06-01 date: 2024-02-21 date: 2024-02-21 name: Raffaele De Caterin... |
The main question the study aims to answer is whether oral sucrosomial iron improved exercise capacity, assessed by six-minute walk test, and quality of life, assessed by Kansas City Cardiomyopathy Questionnaire, compared with placebo. |
One group of participants will receive treatment with oral sucrosomial iron and the other group will receive treatment with placebo. conditions: Chronic Heart Failure conditions: Iron-deficiency conditions: Left Ventricular Systolic Dysfunction studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventio... |
<|newrecord|> nctId: NCT06270485 id: EA2/224/23 briefTitle: Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children acronym: IPCOM overallStatus: RECRUITING date: 2023-11-27 date: 2024-12 date: 2025-06 date: 2024-02-21 date: 2024-02-21 name: Charite University, Berlin,... |
<|newrecord|> nctId: NCT06270472 id: tipp technique briefTitle: Transinguinal Periperitoneal Technique in Inguinal Hernioplasty overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-04-01 date: 2024-02-21 date: 2024-02-21 name: Assiut University class: OTHER briefSummary: evaluation of feasibil... |
<|newrecord|> nctId: NCT06270459 id: DSRB 2023/00954 briefTitle: Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke acronym: TRUST overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2025-08-14 date: 2025-08-14 date: 2024-02-21 date: 2024-02-21 name: Tan Tock Seng Hospital class: OTHER name: Na... |
In this study, the investigators plan to address the low dosage of therapy in the post-acute discharge phase for stroke survivors. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The study is a multi-site prospective clinical trial, wi... |
<|newrecord|> nctId: NCT06270446 id: DSRB 2019/01135 briefTitle: Community Based Rehabilitation Model After Total Knee Replacement overallStatus: COMPLETED date: 2021-01-01 date: 2022-07-01 date: 2022-07-01 date: 2024-02-21 date: 2024-02-21 name: Tan Tock Seng Hospital class: OTHER briefSummary: To investigate the clin... |
<|newrecord|> nctId: NCT06270433 id: 2023-KY142-01 briefTitle: Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder overallStatus: RECRUITING date: 2024-02-19 date: 2024-... |
<|newrecord|> nctId: NCT06270420 id: 2022.04 briefTitle: Technological Devices and Home Automation System in Neurological Rehabilitation acronym: SMART overallStatus: RECRUITING date: 2023-02-05 date: 2024-03-31 date: 2024-05-30 date: 2024-02-21 date: 2024-02-21 name: IRCCS San Camillo, Venezia, Italy class: OTHER brie... |
The main goal of this longitudinal pilot study is to define the productivity of the rehabilitation room (i.e., HoSmartAI room) in the IRCCS San Camillo Hospital (Venice, Italy) service, where the investigators will install home automation sensors and treat patients with neurological disease using technological devices ... |
<|newrecord|> nctId: NCT06270407 id: 270777 id: 2022-001580-28 type: EUDRACT_NUMBER id: 2023-510381-28-00 type: REGISTRY domain: CTIS European Clinical Trial Identification System briefTitle: The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery. overallStat... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.