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Rowing performance test will be conducted at the beginning and at the end of the training camp. Participants will perform a test on a rowing ergometer (Concept II, USA); each subject will have to cover a distance of 2000 m in the shortest possible time which is the distance starting in rowing competitions. The results ... |
Hypotesis: |
The krill oil will infleunce the gut barier integrity. conditions: Endothelial Dysfunction studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: All competitors will be randomly divided into two groups (double-blind): |
A. supplemented (n = 15), who will receive one capsule of a supplement called THYROX (Atlantic krill oil) four times a day. |
B. control (n = 15) receiving placebo. The supplementation period will be six weeks. primaryPurpose: BASIC_SCIENCE masking: TRIPLE maskingDescription: Triple whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: THYROX (Atlantic krill oil name: Placebo measure: I-FA... |
<|newrecord|> nctId: NCT06271421 id: 01/24 briefTitle: NanoTherm In Adjuvant Therapy of Glioblastoma Multiforme acronym: ANCHIALE overallStatus: RECRUITING date: 2024-01-01 date: 2027-02-01 date: 2027-09-01 date: 2024-02-21 date: 2024-02-26 name: Poznan University of Medical Sciences class: OTHER name: MagForce USA bri... |
The goal of the trial is to evaluate the efficacy and tolerance of using the NanoTherm therapy system in recurrent GBM. |
The main questions it aims to answer are: |
1. how NanoTherm therapy influences overall survival, and progression free survival; |
2. what is the tolerance of NanoTherm therapy in terms of side effects (allergies, intracranial bleeding, infections, brain edema, increased intracranial pressure) and quality of life. |
Participants will undergo: |
* initial visit, considering the inclusion/exclusion criteria, neurological examination, and surveys regarding daily functioning and quality of life; |
* standard neurosurgical operation aimed, if possible, complete removal of the recurrent GBM and administration of NanoTherm ASI - a sterile suspension of iron oxide nanoparticles. A catheter will be implanted allowing for measurement of temperature during the first activation in the magnetic field; |
* between the 6th and 10th day after tumor resection, a standard computerized tomography (CT) scan of the head will be performed for routine postoperative evaluation; |
* after the first activation (10th day), the catheter will be removed; |
* subsequently, for 6 times, the patient will be subjected to the variable magnetic field of the NanoActivator® to induce hyperthermia - activations will be conducted on the 10th, 14th, 17th, 21st, 24th, and 28th day; |
* for up to 2 years post-procedure, a CT scan with an evaluation of treatment efficacy will be performed; |
* during follow-up visits for up to 2 years after the surgical procedure, a neurological examination, assessment of adverse symptoms, number of hospitalizations, number of medical visits, clinimetric assessment regarding quality of life, neurological deficit and degree of disability will be conducted. |
Researchers will compare NanoTherm group with patients undergoing Stupp protocol treatment for the abovementioned effects. conditions: Glioblastoma Multiforme studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A prospective longitudinal study will b... |
1. are included for NanoTherm therapy (group A), |
2. are included for standard Stupp protocol (surgery/chemo-radiotherapy) (group B) primaryPurpose: TREATMENT masking: NONE maskingDescription: ANCHIALE is open-label study count: 100 type: ESTIMATED name: NanoTherm therapy name: Glioma Resection name: radiotherapy according to Stupp protocol name: chemotherapy accordin... |
<|newrecord|> nctId: NCT06271408 id: POL-Xe-005 briefTitle: Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging overallStatus: RECRUITING date: 2024-02 date: 2024-04 date: 2024-04 date: 2024-02-21 date: 2024-02-21 ... |
Participants will: |
Receive a standard dose of albuterol delivered using each of 3 aerosol delivery devices. In total, participants will receive three treatments separated by at least 1 week each. |
Following each treatment, participants will have inhale an MRI contrast agent called hyperpolarized Xe 129 and will have images of their lungs taken with an MRI. |
Researchers will compare the different lung images taken after each treatment to see if there are differences in the distribution of air in the lungs (known as ventilation). conditions: Chronic Obstructive Pulmonary Disease studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: CROSSOVER... |
<|newrecord|> nctId: NCT06271395 id: Chaoshengqiunang briefTitle: Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction overallStatus: RECRUITING date: 2024-02-28 date: 2024-10 date: 2024-10 date: 2024-02-21 date: 2024-03-07 name: Zeng Changhao class: OTHER briefSummary: Ultrasound-guided in... |
<|newrecord|> nctId: NCT06271382 id: AIBU-SBF-SA-05 briefTitle: The Effect Of Acupressure and Foot Exercise on Ankle Brachial Index in Individuals With Type 2 Diabetes overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2025-02-15 date: 2025-02-15 date: 2024-02-21 date: 2024-02-21 name: Abant Izzet Baysal Universi... |
<|newrecord|> nctId: NCT06271369 id: CCTL019CUS13 briefTitle: Real-World HRU and Costs in DLBCL Pts With Tisa-cel and Axi-cel, a Medicare Study. overallStatus: COMPLETED date: 2022-08-11 date: 2023-02-15 date: 2023-02-15 date: 2024-02-21 date: 2024-02-21 name: Novartis Pharmaceuticals class: INDUSTRY briefSummary: This... |
Eligible adult patients with r/r DLBCL who were treated with CAR-T therapy were identified from the CMS 100% Medicare data. Patients who received chimeric antigen receptor modified T cell (CAR-T) therapy were further classified into tisa-cel and axi-cel cohorts based on the type of CAR-T treatment received. The index d... |
<|newrecord|> nctId: NCT06271356 id: STU00220278 briefTitle: Breast Cancer - Navigate - Prospective Cohort overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-04 date: 2024-02-21 date: 2024-02-21 name: Northwestern University class: OTHER name: The Chrysalis Initiative briefSummary: The Chrysalis I... |
TCI a nonprofit, breast cancer education and navigation organization is developing methods to address health inequities in cancer care delivery. TCI and its new academic/clinical partner, The Robert H. Lurie Comprehensive Cancer Center of Northwestern University, propose to apply TCI's developed patient navigation supp... |
Therefore, the purpose of this study is to apply TCI's patient navigation-and-coaching program and its website/mobile app (Breast Cancer-Navigate) platform to improve timely initiation to patient adjuvant treatment among WOC breast cancer patients and evaluate the feasibility and preliminary efficacy of this approach. ... |
<|newrecord|> nctId: NCT06271343 id: RC23_0394 briefTitle: Kidney Graft Tolerance KTOL acronym: KTOL overallStatus: RECRUITING date: 2024-03-20 date: 2026-03-01 date: 2026-06-01 date: 2024-02-21 date: 2024-03-21 name: Nantes University Hospital class: OTHER name: Institut National de la Santé Et de la Recherche Médical... |
The study will be carried out on PBMC from both donors and recipients, collected during visits scheduled as part of the clinical management of the donor/recipient pair. |
The study will test the hypothesis that DP8α Tregs expressing CD73, whose frequency in blood increases stably after non-rejected kidney transplants, but not when patients have undergone or will subsequently undergo rejection, are enriched in donor-specific cells, which would be a strong argument in favor of a direct ro... |
<|newrecord|> nctId: NCT06271330 id: AP_JBD_FarWest_004 briefTitle: Multicenter Real-life Observational Study Switched Aflibercept or Ranibizumab to Faricimab in Patients With AMD. acronym: FAR-WEST overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2026-09 date: 2024-02-21 date: 2024-02-21 name: Nante... |
The patients included in the faricimab Phase III study were all naïve to any anti-VEGF treatment. In practice, faricimab is likely to offer hope to patients already treated with anti-VEGF with a short injection interval to lengthen the number of weeks between injections. |
As the treatment will be on sale in pharmacies from October 2023, a switch study from previous anti-VEGF drugs to faricimab would contribute to an initial real-life evaluation of the drug in this indication. conditions: AMD studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 100 ty... |
<|newrecord|> nctId: NCT06271317 id: AP_CL_001 briefTitle: Evaluation of Possible Postoperative Complications After Nissen Sleeve Gastrectomy. French Multicenter Study overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2027-03 date: 2027-03 date: 2024-02-21 date: 2024-02-21 name: Nantes University Hospital class: OT... |
<|newrecord|> nctId: NCT06271304 id: BLUES briefTitle: Stabilizing Mood and Sleep With Blue Blocking Eyewear in Bipolar Disorder acronym: BLUES overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2026-03-01 date: 2026-06-01 date: 2024-02-21 date: 2024-04-17 name: Mental Health Services in the Capital Region, Denma... |
When in a hypomanic or manic phase, participants will be randomized to receive add-on treatment with either blue blocking or low filtration eyewear from 18 PM to 8 AM daily for 7 days. |
After this initial intervention phase, the eyewear is used daily for 3 months in either antimanic dose (14 hours) or maintenance dose (2 hours before bedtime). conditions: Bipolar Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Outcome asses... |
<|newrecord|> nctId: NCT06271291 id: 23-000161 id: NCI-2024-00504 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 23-000161 type: OTHER domain: Mayo Clinic in Rochester id: P30CA015083 type: NIH link: https://reporter.nih.gov/quickSearch/P30CA015083 id: U01CA210138 type: NIH link: https://reporter.ni... |
<|newrecord|> nctId: NCT06271278 id: 2023-17 briefTitle: The Effect of Emotional Freedom Techniques Application on Nurses overallStatus: RECRUITING date: 2023-11-02 date: 2024-02-28 date: 2024-02-28 date: 2024-02-21 date: 2024-02-22 name: Gurkan KAPIKIRAN class: OTHER briefSummary: Nurses working in surgical intensive ... |
<|newrecord|> nctId: NCT06271265 id: 402-C-125 briefTitle: Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-07 date: 2025-07 date: 2024-02-21 date: 2024-02-21 name: Pacira Pharmaceut... |
<|newrecord|> nctId: NCT06271252 id: OriCAR-017 US-P1 briefTitle: A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-12-01 date: 2026-04-01 date: 2024-02-21 date: 2024-04-16 name: OriCell Therapeutics Co., Ltd. class: ... |
RIGEL Study conditions: Neoplasms, Plasma Cell conditions: Neoplasms by Histologic Type conditions: Neoplasms conditions: Hemostatic Disorders conditions: Vascular Diseases conditions: Cardiovascular Diseases conditions: Paraproteinemias conditions: Blood Protein Disorders conditions: Hematologic Diseases conditions: H... |
<|newrecord|> nctId: NCT06271239 id: U1111-1299-9167 id: 65318722.0.0000.5336 type: OTHER domain: IRB-Pontifical Catholic University of Rio Grande do Sul id: RBR-2tq2jky type: OTHER domain: The Brazilian Registry of Clinical Trials (ReBEC) briefTitle: Effect of Multicomponent Exercises VIVIFRAIL® in Older Adults overal... |
In the intervention group (ViviFrail), 25 participants will be instructed to engage in tailored physical exercises outlined in the VIVIFRAIL® protocol within the confines of their homes, with adaptations made according to their clinical conditions and functional performance. |
Conversely, the Group Suggestions for a Healthy Life (CG) comprising 25 participants will receive exercise suggestions and guidance to maintain a healthy routine for a duration of three months. Subsequently, participants in the CG will undergo the VIVIFRAIL® program intervention for an additional three months. conditio... |
The Group Suggestions for a Healthy Life (CG) will receive exercise suggestions and guidance for maintaining a healthy routine for three months. After, they will undergo a three-month intervention using the VIVIFRAIL® protocol. |
Sample size determination was based on Casas-Herrero et al. (2022). The study assessed the impact of multicomponent training on intrinsic functional capacity, utilizing the Short Physical Performance Battery (SPPB) to gauge balance, gait speed, and lower limb strength on a 0 to 12 scale. Control group: -0.33±1.60 point... |
Considering a 5% alpha and 80% power, 20 participants per group are required. Anticipating a 25% dropout rate, as observed by Tiecker (2021), we plan to enroll 25 participants per group. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: The assessments will be conducted by trained researchers whoMasked: OU... |
<|newrecord|> nctId: NCT06271226 id: OMUKAEK 2022/75 id: OMUKAEK 2022/75 type: OTHER domain: ONDOKUZ MAYIS UNIVERSTY briefTitle: The Effect of Acupressure Applied to Icu on Pain and Physiological Parameters acronym: EFFECTOFACU overallStatus: RECRUITING date: 2023-03-20 date: 2024-06-30 date: 2024-12-31 date: 2024-02-2... |
The main questions that the study aims to answer are: |
Acupressure applied to intensive care patients has no effect on pain. Acupressure applied to intensive care patients has an effect on pain. Acupressure applied to intensive care patients has no effect on physiological parameters. |
Acupressure applied to intensive care patients has an effect on physiological parameters. |
Participants will be included in the study after obtaining consent from patients who were treated in the intensive care unit, who scored 9 and above on the glaskow coma scale by evaluating their consciousness status, and had pain after evaluating their pain. conditions: Intensive Care Patients conditions: Pain studyTyp... |
<|newrecord|> nctId: NCT06271213 id: 303841 briefTitle: The Gut-Lung Axis and Respiratory Illness in Children overallStatus: RECRUITING date: 2024-02-04 date: 2027-11-01 date: 2028-05-01 date: 2024-02-21 date: 2024-02-21 name: NHS Greater Glasgow and Clyde class: OTHER name: University of Glasgow briefSummary: The goal... |
Part A is a cross-sectional study design investigating the postulated bidirectional link between the gut and lung microbiomes in children suffering from respiratory or gastrointestinal conditions. Children with no GI or respiratory issues attending for orthopaedic care will be used as a benchmark for a healthy gut-lung... |
* What does a healthy gut-lung axis look like? |
* Do children with respiratory issues show an altered gut microbiome? |
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