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# The Comparative Toxicogenomics Database (CTD) - http://ctdbase.org/
# Copyright 2002-2012 MDI Biological Laboratory. All rights reserved.
# Copyright 2012-2023 NC State University. All rights reserved.
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# Report created: Fri Oct 27 12:42:19 EDT 2023
#
# Fields:
# PathwayName PathwayID
#
2-LTR circle formation REACT:R-HSA-164843
2-Oxocarboxylic acid metabolism KEGG:hsa01210
5-Phosphoribose 1-diphosphate biosynthesis REACT:R-HSA-73843
Abacavir metabolism REACT:R-HSA-2161541
Abacavir transmembrane transport REACT:R-HSA-2161517
Abacavir transport and metabolism REACT:R-HSA-2161522
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway REACT:R-HSA-73930
ABC-family proteins mediated transport REACT:R-HSA-382556
ABC transporter disorders REACT:R-HSA-5619084
ABC transporters KEGG:hsa02010
ABC transporters in lipid homeostasis REACT:R-HSA-1369062
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate REACT:R-HSA-2978092
Abortive elongation of HIV-1 transcript in the absence of Tat REACT:R-HSA-167242
Acetylation REACT:R-HSA-156582
Acetylcholine Binding And Downstream Events REACT:R-HSA-181431
Acetylcholine Neurotransmitter Release Cycle REACT:R-HSA-264642
Acetylcholine regulates insulin secretion REACT:R-HSA-399997
Acrosome Reaction REACT:R-HSA-1300645
Activated NOTCH1 Transmits Signal to the Nucleus REACT:R-HSA-2122948
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 REACT:R-HSA-5625886
Activated point mutants of FGFR2 REACT:R-HSA-2033519
activated TAK1 mediates p38 MAPK activation REACT:R-HSA-450302
Activated TLR4 signalling REACT:R-HSA-166054
Activation and oligomerization of BAK protein REACT:R-HSA-111452
Activation, myristolyation of BID and translocation to mitochondria REACT:R-HSA-75108
Activation of AKT2 REACT:R-HSA-165158
Activation of AMPA receptors REACT:R-HSA-399710
Activation of anterior HOX genes in hindbrain development during early embryogenesis REACT:R-HSA-5617472
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176814
Activation of ATR in response to replication stress REACT:R-HSA-176187
Activation of BAD and translocation to mitochondria REACT:R-HSA-111447
Activation of BH3-only proteins REACT:R-HSA-114452
Activation of BIM and translocation to mitochondria REACT:R-HSA-111446
Activation of BMF and translocation to mitochondria REACT:R-HSA-139910
Activation of C3 and C5 REACT:R-HSA-174577
Activation of CaMK IV REACT:R-HSA-442745
Activation of Ca-permeable Kainate Receptor REACT:R-HSA-451308
Activation of caspases through apoptosome-mediated cleavage REACT:R-HSA-111459
Activation of DNA fragmentation factor REACT:R-HSA-211227
Activation of GABAB receptors REACT:R-HSA-991365
Activation of gene expression by SREBF (SREBP) REACT:R-HSA-2426168
Activation of G protein gated Potassium channels REACT:R-HSA-1296041
Activation of HOX genes during differentiation REACT:R-HSA-5619507
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon REACT:R-HSA-936964
Activation of Kainate Receptors upon glutamate binding REACT:R-HSA-451326
Activation of Matrix Metalloproteinases REACT:R-HSA-1592389
Activation of Na-permeable Kainate Receptors REACT:R-HSA-451307
Activation of NF-kappaB in B cells REACT:R-HSA-1169091
Activation of Nicotinic Acetylcholine Receptors REACT:R-HSA-629602
Activation of NIMA Kinases NEK9, NEK6, NEK7 REACT:R-HSA-2980767
Activation of NMDA receptor upon glutamate binding and postsynaptic events REACT:R-HSA-442755
Activation of NOXA and translocation to mitochondria REACT:R-HSA-111448
Activation of PPARGC1A (PGC-1alpha) by phosphorylation REACT:R-HSA-2151209
Activation of PUMA and translocation to mitochondria REACT:R-HSA-139915
Activation of Rac REACT:R-HSA-428540
Activation of RAS in B cells REACT:R-HSA-1169092
Activation of SMO REACT:R-HSA-5635838
Activation of the AP-1 family of transcription factors REACT:R-HSA-450341
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S REACT:R-HSA-72662
Activation of the phototransduction cascade REACT:R-HSA-2485179
Activation of the pre-replicative complex REACT:R-HSA-68962
Activation of the TFAP2 (AP-2) family of transcription factors REACT:R-HSA-8866907
Activation of TRKA receptors REACT:R-HSA-187015
Activation, translocation and oligomerization of BAX REACT:R-HSA-114294
Activin signaling KEGG:hsa_M00681
Acute myeloid leukemia KEGG:hsa05221
Acyl chain remodeling of CL REACT:R-HSA-1482798
Acyl chain remodeling of DAG and TAG REACT:R-HSA-1482883
Acyl chain remodelling of PC REACT:R-HSA-1482788
Acyl chain remodelling of PE REACT:R-HSA-1482839
Acyl chain remodelling of PG REACT:R-HSA-1482925
Acyl chain remodelling of PI REACT:R-HSA-1482922
Acyl chain remodelling of PS REACT:R-HSA-1482801
Acylglycerol degradation KEGG:hsa_M00098
Adaptive Immune System REACT:R-HSA-1280218
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP KEGG:hsa_M00049
Adenosine P1 receptors REACT:R-HSA-417973
Adenylate cyclase activating pathway REACT:R-HSA-170660
Adenylate cyclase inhibitory pathway REACT:R-HSA-170670
Adherens junction KEGG:hsa04520
Adherens junctions interactions REACT:R-HSA-418990
Adipocytokine signaling pathway KEGG:hsa04920
ADP signalling through P2Y purinoceptor 1 REACT:R-HSA-418592
ADP signalling through P2Y purinoceptor 12 REACT:R-HSA-392170
Adrenaline,noradrenaline inhibits insulin secretion REACT:R-HSA-400042
Adrenaline signalling through Alpha-2 adrenergic receptor REACT:R-HSA-392023
Adrenergic signaling in cardiomyocytes KEGG:hsa04261
Adrenoceptors REACT:R-HSA-390696
Advanced glycosylation endproduct receptor signaling REACT:R-HSA-879415
Aflatoxin activation and detoxification REACT:R-HSA-5423646
African trypanosomiasis KEGG:hsa05143
AGE-RAGE signaling pathway in diabetic complications KEGG:hsa04933
Agmatine biosynthesis REACT:R-HSA-351143
AKT-mediated inactivation of FOXO1A REACT:R-HSA-211163
AKT phosphorylates targets in the cytosol REACT:R-HSA-198323
AKT phosphorylates targets in the nucleus REACT:R-HSA-198693
Alanine, aspartate and glutamate metabolism KEGG:hsa00250
Alcoholism KEGG:hsa05034
Aldosterone-regulated sodium reabsorption KEGG:hsa04960
Aldosterone synthesis and secretion KEGG:hsa04925
ALKBH2 mediated reversal of alkylation damage REACT:R-HSA-112122
ALKBH3 mediated reversal of alkylation damage REACT:R-HSA-112126
Allograft rejection KEGG:hsa05330
Alpha-defensins REACT:R-HSA-1462054
alpha-linolenic acid (ALA) metabolism REACT:R-HSA-2046106
alpha-Linolenic acid metabolism KEGG:hsa00592
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism REACT:R-HSA-2046104
Alpha-oxidation of phytanate REACT:R-HSA-389599
Alternative complement activation REACT:R-HSA-173736
Alzheimer's disease KEGG:hsa05010
AMER1 mutants destabilize the destruction complex REACT:R-HSA-4839748
Amine-derived hormones REACT:R-HSA-209776
Amine ligand-binding receptors REACT:R-HSA-375280
Amine Oxidase reactions REACT:R-HSA-140179
Amino Acid conjugation REACT:R-HSA-156587
Amino acid synthesis and interconversion (transamination) REACT:R-HSA-70614
Amino acid transport across the plasma membrane REACT:R-HSA-352230
Aminoacyl-tRNA biosynthesis KEGG:hsa00970
Aminoacyl-tRNA biosynthesis, eukaryotes KEGG:hsa_M00359
Amino sugar and nucleotide sugar metabolism KEGG:hsa00520
Amoebiasis KEGG:hsa05146
Amphetamine addiction KEGG:hsa05031
AMPK inhibits chREBP transcriptional activation activity REACT:R-HSA-163680
AMPK signaling pathway KEGG:hsa04152
Amplification of signal from the kinetochores REACT:R-HSA-141424
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal REACT:R-HSA-141444
Amyloid fiber formation REACT:R-HSA-977225
Amyotrophic lateral sclerosis (ALS) KEGG:hsa05014
Anchoring fibril formation REACT:R-HSA-2214320
Anchoring of the basal body to the plasma membrane REACT:R-HSA-5620912
Androgen biosynthesis REACT:R-HSA-193048
Antagonism of Activin by Follistatin REACT:R-HSA-2473224
Antifolate resistance KEGG:hsa01523
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers REACT:R-HSA-983695
Antigen Presentation: Folding, assembly and peptide loading of class I MHC REACT:R-HSA-983170
Antigen processing and presentation KEGG:hsa04612
Antigen processing-Cross presentation REACT:R-HSA-1236975
Antigen processing: Ubiquitination & Proteasome degradation REACT:R-HSA-983168
Antimicrobial peptides REACT:R-HSA-6803157
Antiviral mechanism by IFN-stimulated genes REACT:R-HSA-1169410
APC/C:Cdc20 mediated degradation of Cyclin B REACT:R-HSA-174048
APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176409
APC/C:Cdc20 mediated degradation of Securin REACT:R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 REACT:R-HSA-174178
APC/C complex KEGG:hsa_M00389
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint REACT:R-HSA-179419
APC-Cdc20 mediated degradation of Nek2A REACT:R-HSA-179409
APC/C-mediated degradation of cell cycle proteins REACT:R-HSA-174143
APC truncation mutants are not K63 polyubiquitinated REACT:R-HSA-5467333
APC truncation mutants have impaired AXIN binding REACT:R-HSA-5467337
Apelin signaling pathway KEGG:hsa04371
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway REACT:R-HSA-5649702
APOBEC3G mediated resistance to HIV-1 infection REACT:R-HSA-180689
Apoptosis KEGG:hsa04210
Apoptosis REACT:R-HSA-109581
Apoptosis induced DNA fragmentation REACT:R-HSA-140342
Apoptosis - multiple species KEGG:hsa04215
Apoptotic cleavage of cell adhesion proteins REACT:R-HSA-351906
Apoptotic cleavage of cellular proteins REACT:R-HSA-111465
Apoptotic execution phase REACT:R-HSA-75153
Apoptotic factor-mediated response REACT:R-HSA-111471
Apoptotic machinery KEGG:hsa_M00685
Aquaporin-mediated transport REACT:R-HSA-445717
Arachidonate production from DAG REACT:R-HSA-426048
Arachidonic acid metabolism KEGG:hsa00590
Arachidonic acid metabolism REACT:R-HSA-2142753
Arginine and proline metabolism KEGG:hsa00330
Arginine biosynthesis KEGG:hsa00220
ARL13B-mediated ciliary trafficking of INPP5E REACT:R-HSA-5624958
ARMS-mediated activation REACT:R-HSA-170984
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 REACT:R-HSA-211957
Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG:hsa05412
Aryl hydrocarbon receptor signalling REACT:R-HSA-8937144
Ascorbate and aldarate metabolism KEGG:hsa00053
Asparagine N-linked glycosylation REACT:R-HSA-446203
Assembly of collagen fibrils and other multimeric structures REACT:R-HSA-2022090
Assembly Of The HIV Virion REACT:R-HSA-175474
Assembly of the ORC complex at the origin of replication REACT:R-HSA-68616
Assembly of the pre-replicative complex REACT:R-HSA-68867
Assembly of Viral Components at the Budding Site REACT:R-HSA-168316
Association of licensing factors with the pre-replicative complex REACT:R-HSA-69298
Association of TriC/CCT with target proteins during biosynthesis REACT:R-HSA-390471
Asthma KEGG:hsa05310
Astrocytic Glutamate-Glutamine Uptake And Metabolism REACT:R-HSA-210455
Asymmetric localization of PCP proteins REACT:R-HSA-4608870
A tetrasaccharide linker sequence is required for GAG synthesis REACT:R-HSA-1971475
ATF4 activates genes REACT:R-HSA-380994
ATF6 (ATF6-alpha) activates chaperone genes REACT:R-HSA-381183
ATF6 (ATF6-alpha) activates chaperones REACT:R-HSA-381033
ATP sensitive Potassium channels REACT:R-HSA-1296025
Attachment of GPI anchor to uPAR REACT:R-HSA-162791
Attenuation phase REACT:R-HSA-3371568
AUF1 (hnRNP D0) binds and destabilizes mRNA REACT:R-HSA-450408
AURKA Activation by TPX2 REACT:R-HSA-8854518
Autodegradation of Cdh1 by Cdh1:APC/C REACT:R-HSA-174084
Autodegradation of the E3 ubiquitin ligase COP1 REACT:R-HSA-349425
Autoimmune thyroid disease KEGG:hsa05320
Autointegration results in viral DNA circles REACT:R-HSA-177539
Autophagy - animal KEGG:hsa04140
Autophagy - other KEGG:hsa04136
AXIN missense mutants destabilize the destruction complex REACT:R-HSA-5467340
AXIN mutants destabilize the destruction complex, activating WNT signaling REACT:R-HSA-4839735
Axonal growth inhibition (RHOA activation) REACT:R-HSA-193634
Axonal growth stimulation REACT:R-HSA-209563
Axon guidance KEGG:hsa04360
Axon guidance REACT:R-HSA-422475
Bacterial invasion of epithelial cells KEGG:hsa05100
Basal cell carcinoma KEGG:hsa05217
Basal transcription factors KEGG:hsa03022
Base excision repair KEGG:hsa03410
Base Excision Repair REACT:R-HSA-73884
Base-Excision Repair, AP Site Formation REACT:R-HSA-73929
Basigin interactions REACT:R-HSA-210991
BBSome-mediated cargo-targeting to cilium REACT:R-HSA-5620922
B cell receptor signaling pathway KEGG:hsa04662
BER complex KEGG:hsa_M00296
beta-Alanine metabolism KEGG:hsa00410
Beta-catenin independent WNT signaling REACT:R-HSA-3858494
Beta-catenin phosphorylation cascade REACT:R-HSA-196299
Beta defensins REACT:R-HSA-1461957
betaKlotho-mediated ligand binding REACT:R-HSA-1307965
beta-Oxidation KEGG:hsa_M00087
beta-Oxidation, acyl-CoA synthesis KEGG:hsa_M00086
Beta oxidation of butanoyl-CoA to acetyl-CoA REACT:R-HSA-77352
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA REACT:R-HSA-77346
Beta oxidation of hexanoyl-CoA to butanoyl-CoA REACT:R-HSA-77350
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA REACT:R-HSA-77310
Beta oxidation of myristoyl-CoA to lauroyl-CoA REACT:R-HSA-77285
Beta oxidation of octanoyl-CoA to hexanoyl-CoA REACT:R-HSA-77348
Beta oxidation of palmitoyl-CoA to myristoyl-CoA REACT:R-HSA-77305
Beta-oxidation of pristanoyl-CoA REACT:R-HSA-389887
Beta-oxidation of very long chain fatty acids REACT:R-HSA-390247
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members REACT:R-HSA-111453
Bicarbonate transporters REACT:R-HSA-425381
Bile acid and bile salt metabolism REACT:R-HSA-194068
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate KEGG:hsa_M00104
Bile secretion KEGG:hsa04976
Binding and entry of HIV virion REACT:R-HSA-173107
Binding and Uptake of Ligands by Scavenger Receptors REACT:R-HSA-2173782
Binding of TCF/LEF:CTNNB1 to target gene promoters REACT:R-HSA-4411364
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB REACT:R-HSA-141333
Biological oxidations REACT:R-HSA-211859
Biosynthesis of A2E, implicated in retinal degradation REACT:R-HSA-2466712
Biosynthesis of amino acids KEGG:hsa01230
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein REACT:R-HSA-446193
Biosynthesis of unsaturated fatty acids KEGG:hsa01040
Biotin metabolism KEGG:hsa00780
Biotin transport and metabolism REACT:R-HSA-196780
Bladder cancer KEGG:hsa05219
Bloom's syndrome complex KEGG:hsa_M00414
BMAL1:CLOCK,NPAS2 activates circadian gene expression REACT:R-HSA-1368108
BMP signaling KEGG:hsa_M00679
Branched-chain amino acid catabolism REACT:R-HSA-70895
BRCA1-associated genome surveillance complex (BASC) KEGG:hsa_M00295
Breakdown of the nuclear lamina REACT:R-HSA-352238
Breast cancer KEGG:hsa05224
Budding REACT:R-HSA-168302
Budding and maturation of HIV virion REACT:R-HSA-162588
Butanoate metabolism KEGG:hsa00650
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA REACT:R-HSA-450385
Butyrophilin (BTN) family interactions REACT:R-HSA-8851680
B-WICH complex positively regulates rRNA expression REACT:R-HSA-5250924
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone KEGG:hsa_M00110
C1-unit interconversion, eukaryotes KEGG:hsa_M00141
C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone KEGG:hsa_M00108
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone KEGG:hsa_M00109
C5 isoprenoid biosynthesis, mevalonate pathway KEGG:hsa_M00095
C6 deamination of adenosine REACT:R-HSA-75102
Ca2+ activated K+ channels REACT:R-HSA-1296052
Ca2+ pathway REACT:R-HSA-4086398
Ca-dependent events REACT:R-HSA-111996
Caffeine metabolism KEGG:hsa00232
Calcitonin-like ligand receptors REACT:R-HSA-419812
Calcium signaling pathway KEGG:hsa04020
Calmodulin induced events REACT:R-HSA-111933
Calnexin/calreticulin cycle REACT:R-HSA-901042
CaMK IV-mediated phosphorylation of CREB REACT:R-HSA-111932
CaM pathway REACT:R-HSA-111997
Cam-PDE 1 activation REACT:R-HSA-111957
cAMP signaling KEGG:hsa_M00695
cAMP signaling pathway KEGG:hsa04024
Cap binding complex KEGG:hsa_M00399
Cap-dependent Translation Initiation REACT:R-HSA-72737
Carbohydrate digestion and absorption KEGG:hsa04973
Carbon metabolism KEGG:hsa01200
Cardiac conduction REACT:R-HSA-5576891
Cardiac muscle contraction KEGG:hsa04260
Cargo concentration in the ER REACT:R-HSA-5694530
Cargo recognition for clathrin-mediated endocytosis REACT:R-HSA-8856825
Cargo trafficking to the periciliary membrane REACT:R-HSA-5620920
Carnitine synthesis REACT:R-HSA-71262
CASP8 activity is inhibited REACT:R-HSA-5218900
Caspase activation via extrinsic apoptotic signalling pathway REACT:R-HSA-5357769
Caspase-mediated cleavage of cytoskeletal proteins REACT:R-HSA-264870
Catabolism of glucuronate to xylulose-5-phosphate REACT:R-HSA-5661270
Catecholamine biosynthesis REACT:R-HSA-209905
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline KEGG:hsa_M00042
Cation-coupled Chloride cotransporters REACT:R-HSA-426117
CD209 (DC-SIGN) signaling REACT:R-HSA-5621575
CD22 mediated BCR regulation REACT:R-HSA-5690714
CD28 co-stimulation REACT:R-HSA-389356
CD28 dependent PI3K/Akt signaling REACT:R-HSA-389357
CD28 dependent Vav1 pathway REACT:R-HSA-389359
Cdc20:Phospho-APC/C mediated degradation of Cyclin A REACT:R-HSA-174184
CDC6 association with the ORC:origin complex REACT:R-HSA-68689
CDK-mediated phosphorylation and removal of Cdc6 REACT:R-HSA-69017
CDO in myogenesis REACT:R-HSA-375170
CDT1 association with the CDC6:ORC:origin complex REACT:R-HSA-68827
Cell adhesion molecules (CAMs) KEGG:hsa04514
Cell-Cell communication REACT:R-HSA-1500931
Cell-cell junction organization REACT:R-HSA-421270
Cell cycle KEGG:hsa04110
Cell Cycle REACT:R-HSA-1640170
Cell Cycle Checkpoints REACT:R-HSA-69620
Cell cycle - G1/S transition KEGG:hsa_M00692
Cell cycle - G2/M transition KEGG:hsa_M00693
Cell Cycle, Mitotic REACT:R-HSA-69278
Cell death signalling via NRAGE, NRIF and NADE REACT:R-HSA-204998
Cell-extracellular matrix interactions REACT:R-HSA-446353
Cell junction organization REACT:R-HSA-446728
Cell redox homeostasis REACT:R-HSA-1222541
Cell surface interactions at the vascular wall REACT:R-HSA-202733
Cellular responses to stress REACT:R-HSA-2262752
Cellular response to heat stress REACT:R-HSA-3371556
Cellular response to hypoxia REACT:R-HSA-2262749
Cellular Senescence REACT:R-HSA-2559583
Central carbon metabolism in cancer KEGG:hsa05230
Centrosome maturation REACT:R-HSA-380287
Ceramide biosynthesis KEGG:hsa_M00094
Ceramide signalling REACT:R-HSA-193681
cGMP effects REACT:R-HSA-418457
cGMP-PKG signaling pathway KEGG:hsa04022
cGMP signaling KEGG:hsa_M00694
Chagas disease (American trypanosomiasis) KEGG:hsa05142
Chaperonin-mediated protein folding REACT:R-HSA-390466
Chemical carcinogenesis KEGG:hsa05204
Chemokine receptors bind chemokines REACT:R-HSA-380108
Chemokine signaling pathway KEGG:hsa04062
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex REACT:R-HSA-75035
CHL1 interactions REACT:R-HSA-447041
Cholecalciferol biosynthesis KEGG:hsa_M00103
Cholesterol biosynthesis REACT:R-HSA-191273
Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol KEGG:hsa_M00101
Cholesterol biosynthesis via desmosterol REACT:R-HSA-6807047
Cholesterol biosynthesis via lathosterol REACT:R-HSA-6807062
Choline catabolism REACT:R-HSA-6798163
Choline metabolism in cancer KEGG:hsa05231
Cholinergic synapse KEGG:hsa04725
Chondroitin sulfate biosynthesis REACT:R-HSA-2022870
Chondroitin sulfate degradation KEGG:hsa_M00077
Chondroitin sulfate/dermatan sulfate metabolism REACT:R-HSA-1793185
ChREBP activates metabolic gene expression REACT:R-HSA-163765
Chromatin modifying enzymes REACT:R-HSA-3247509
Chromatin organization REACT:R-HSA-4839726
Chromosome Maintenance REACT:R-HSA-73886
Chronic myeloid leukemia KEGG:hsa05220
Chylomicron-mediated lipid transport REACT:R-HSA-174800
Cilium Assembly REACT:R-HSA-5617833
Circadian Clock REACT:R-HSA-400253
Circadian entrainment KEGG:hsa04713
Circadian rhythm KEGG:hsa04710
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate KEGG:hsa_M00010
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate KEGG:hsa_M00011
Citrate cycle (TCA cycle) KEGG:hsa00020
Citrate cycle (TCA cycle, Krebs cycle) KEGG:hsa_M00009
Citric acid cycle (TCA cycle) REACT:R-HSA-71403
Class A/1 (Rhodopsin-like receptors) REACT:R-HSA-373076
Class B/2 (Secretin family receptors) REACT:R-HSA-373080
Class C/3 (Metabotropic glutamate/pheromone receptors) REACT:R-HSA-420499
Classical antibody-mediated complement activation REACT:R-HSA-173623
Classical Kir channels REACT:R-HSA-1296053
Class II GLUTs REACT:R-HSA-428776
Class I MHC mediated antigen processing & presentation REACT:R-HSA-983169
Clathrin derived vesicle budding REACT:R-HSA-421837
Clathrin-mediated endocytosis REACT:R-HSA-8856828
Clearance of Nuclear Envelope Membranes from Chromatin REACT:R-HSA-2993913
Cleavage of Growing Transcript in the Termination Region REACT:R-HSA-109688
Cleavage of the damaged purine REACT:R-HSA-110331
Cleavage of the damaged pyrimidine REACT:R-HSA-110329
CLEC7A (Dectin-1) induces NFAT activation REACT:R-HSA-5607763
CLEC7A (Dectin-1) signaling REACT:R-HSA-5607764
CLEC7A/inflammasome pathway REACT:R-HSA-5660668
Cobalamin (Cbl, vitamin B12) transport and metabolism REACT:R-HSA-196741
Cocaine addiction KEGG:hsa05030
Coenzyme A biosynthesis REACT:R-HSA-196783
Coenzyme A biosynthesis, pantothenate => CoA KEGG:hsa_M00120
Cohesin Loading onto Chromatin REACT:R-HSA-2470946
Collagen biosynthesis and modifying enzymes REACT:R-HSA-1650814
Collagen chain trimerization REACT:R-HSA-8948216
Collagen degradation REACT:R-HSA-1442490
Collagen formation REACT:R-HSA-1474290
Collecting duct acid secretion KEGG:hsa04966
Colorectal cancer KEGG:hsa05210
Common Pathway of Fibrin Clot Formation REACT:R-HSA-140875
Complement and coagulation cascades KEGG:hsa04610
Complement cascade REACT:R-HSA-166658
Complex I biogenesis REACT:R-HSA-6799198
Condensation of Prometaphase Chromosomes REACT:R-HSA-2514853
Condensation of Prophase Chromosomes REACT:R-HSA-2299718
Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate KEGG:hsa_M00106
Conjugation of benzoate with glycine REACT:R-HSA-177135
Conjugation of carboxylic acids REACT:R-HSA-159424
Conjugation of phenylacetate with glutamine REACT:R-HSA-177162
Conjugation of salicylate with glycine REACT:R-HSA-177128
Constitutive Signaling by Aberrant PI3K in Cancer REACT:R-HSA-2219530
Constitutive Signaling by AKT1 E17K in Cancer REACT:R-HSA-5674400
Constitutive Signaling by EGFRvIII REACT:R-HSA-5637810
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants REACT:R-HSA-1236382
Constitutive Signaling by NOTCH1 HD Domain Mutants REACT:R-HSA-2691232
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants REACT:R-HSA-2894862
Constitutive Signaling by NOTCH1 PEST Domain Mutants REACT:R-HSA-2644606
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660826
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase REACT:R-HSA-176407
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding REACT:R-HSA-6814122
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding REACT:R-HSA-389958
COPI-dependent Golgi-to-ER retrograde traffic REACT:R-HSA-6811434
COPII (Coat Protein 2) Mediated Vesicle Transport REACT:R-HSA-204005
COPII complex KEGG:hsa_M00404
COPI-independent Golgi-to-ER retrograde traffic REACT:R-HSA-6811436
COPI-mediated anterograde transport REACT:R-HSA-6807878
Costimulation by the CD28 family REACT:R-HSA-388841
COX reactions REACT:R-HSA-140180
Creatine metabolism REACT:R-HSA-71288
Creatine pathway KEGG:hsa_M00047
Creation of C4 and C2 activators REACT:R-HSA-166786
CREB phosphorylation REACT:R-HSA-199920
CREB phosphorylation through the activation of Adenylate Cyclase REACT:R-HSA-442720
CREB phosphorylation through the activation of CaMKII REACT:R-HSA-442729
CREB phosphorylation through the activation of CaMKK REACT:R-HSA-442717
CREB phosphorylation through the activation of Ras REACT:R-HSA-442742
CRMPs in Sema3A signaling REACT:R-HSA-399956
cRNA Synthesis REACT:R-HSA-192869
Crosslinking of collagen fibrils REACT:R-HSA-2243919
Cross-presentation of particulate exogenous antigens (phagosomes) REACT:R-HSA-1236973
Cross-presentation of soluble exogenous antigens (endosomes) REACT:R-HSA-1236978
CS/DS degradation REACT:R-HSA-2024101
c-src mediated regulation of Cx43 function and closure of gap junctions REACT:R-HSA-191647
CTLA4 inhibitory signaling REACT:R-HSA-389513
C-type lectin receptors (CLRs) REACT:R-HSA-5621481
Cul3-SPOP complex KEGG:hsa_M00384
Cul4-DDB1-CSA complex KEGG:hsa_M00386
Cul4-DDB1-DDB2 complex KEGG:hsa_M00385
Cyclin A/B1 associated events during G2/M transition REACT:R-HSA-69273
Cyclin A:Cdk2-associated events at S phase entry REACT:R-HSA-69656
Cyclin B2 mediated events REACT:R-HSA-157881
Cyclin D associated events in G1 REACT:R-HSA-69231
Cyclin E associated events during G1/S transition REACT:R-HSA-69202
CYP2E1 reactions REACT:R-HSA-211999
Cysteine and methionine metabolism KEGG:hsa00270
Cysteine biosynthesis, homocysteine + serine => cysteine KEGG:hsa_M00338
Cysteine formation from homocysteine REACT:R-HSA-1614603
Cytochrome bc1 complex KEGG:hsa_M00152
Cytochrome bc1 complex respiratory unit KEGG:hsa_M00151
Cytochrome c-mediated apoptotic response REACT:R-HSA-111461
Cytochrome c oxidase KEGG:hsa_M00154
Cytochrome P450 - arranged by substrate type REACT:R-HSA-211897
Cytokine-cytokine receptor interaction KEGG:hsa04060
Cytokine Signaling in Immune system REACT:R-HSA-1280215
Cytosolic DNA-sensing pathway KEGG:hsa04623
Cytosolic iron-sulfur cluster assembly REACT:R-HSA-2564830
Cytosolic sensors of pathogen-associated DNA REACT:R-HSA-1834949
Cytosolic sulfonation of small molecules REACT:R-HSA-156584
Cytosolic tRNA aminoacylation REACT:R-HSA-379716
DAG and IP3 signaling REACT:R-HSA-1489509
DAP12 interactions REACT:R-HSA-2172127
DAP12 signaling REACT:R-HSA-2424491
D-Arginine and D-ornithine metabolism KEGG:hsa00472
DARPP-32 events REACT:R-HSA-180024
DCC mediated attractive signaling REACT:R-HSA-418885
Deactivation of the beta-catenin transactivating complex REACT:R-HSA-3769402
Deadenylation-dependent mRNA decay REACT:R-HSA-429914
Deadenylation of mRNA REACT:R-HSA-429947
Death Receptor Signalling REACT:R-HSA-73887
Decapping complex KEGG:hsa_M00395
Dectin-1 mediated noncanonical NF-kB signaling REACT:R-HSA-5607761
Dectin-2 family REACT:R-HSA-5621480
Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B REACT:R-HSA-5682294
Defective ABCA1 causes Tangier disease REACT:R-HSA-5682113
Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3) REACT:R-HSA-5688399
Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) REACT:R-HSA-5683678
Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2 REACT:R-HSA-5678520
Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1 REACT:R-HSA-5678771
Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) REACT:R-HSA-5683371
Defective ABCC2 causes Dubin-Johnson syndrome REACT:R-HSA-5679001
Defective ABCC6 causes pseudoxanthoma elasticum (PXE) REACT:R-HSA-5690338
Defective ABCC8 can cause hypoglycemias and hyperglycemias REACT:R-HSA-5683177
Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia REACT:R-HSA-5678420
Defective ABCD1 causes adrenoleukodystrophy (ALD) REACT:R-HSA-5684045
Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ) REACT:R-HSA-5683329
Defective ABCG5 causes sitosterolemia REACT:R-HSA-5679096
Defective ABCG8 causes gallbladder disease 4 and sitosterolemia REACT:R-HSA-5679090
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) REACT:R-HSA-5579031
Defective ACY1 causes encephalopathy REACT:R-HSA-5579007
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) REACT:R-HSA-5578997
Defective ALG11 causes ALG11-CDG (CDG-1p) REACT:R-HSA-4551295
Defective ALG12 causes ALG12-CDG (CDG-1g) REACT:R-HSA-4720489
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) REACT:R-HSA-5633231
Defective ALG1 causes ALG1-CDG (CDG-1k) REACT:R-HSA-4549380
Defective ALG2 causes ALG2-CDG (CDG-1i) REACT:R-HSA-4549349
Defective ALG3 causes ALG3-CDG (CDG-1d) REACT:R-HSA-4720475
Defective ALG6 causes ALG6-CDG (CDG-1c) REACT:R-HSA-4724289
Defective ALG8 causes ALG8-CDG (CDG-1h) REACT:R-HSA-4724325
Defective ALG9 causes ALG9-CDG (CDG-1l) REACT:R-HSA-4720454
Defective AMN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359462
Defective AVP causes neurohypophyseal diabetes insipidus (NDI) REACT:R-HSA-5619099
Defective B3GALT6 causes EDSP2 and SEMDJL1 REACT:R-HSA-4420332
Defective B3GALTL causes Peters-plus syndrome (PpS) REACT:R-HSA-5083635
Defective B3GAT3 causes JDSSDHD REACT:R-HSA-3560801
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-3656244
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-4793953
Defective B4GALT7 causes EDS, progeroid type REACT:R-HSA-3560783
Defective BTD causes biotidinase deficiency REACT:R-HSA-3371598
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) REACT:R-HSA-5083632
Defective CD320 causes methylmalonic aciduria REACT:R-HSA-3359485
Defective CFTR causes cystic fibrosis REACT:R-HSA-5678895
Defective CHST14 causes EDS, musculocontractural type REACT:R-HSA-3595174
Defective CHST3 causes SEDCJD REACT:R-HSA-3595172
Defective CHST6 causes MCDC1 REACT:R-HSA-3656225
Defective CHSY1 causes TPBS REACT:R-HSA-3595177
Defective CP causes aceruloplasminemia (ACERULOP) REACT:R-HSA-5619060
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) REACT:R-HSA-5688890
Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) REACT:R-HSA-5688849
Defective CUBN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359463
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) REACT:R-HSA-5579026
Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) REACT:R-HSA-5579017
Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) REACT:R-HSA-5579009
Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) REACT:R-HSA-5579028
Defective CYP19A1 causes Aromatase excess syndrome (AEXS) REACT:R-HSA-5579030
Defective CYP1B1 causes Glaucoma REACT:R-HSA-5579000
Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) REACT:R-HSA-5579021
Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) REACT:R-HSA-5579010
Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) REACT:R-HSA-5579015
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) REACT:R-HSA-5579004
Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) REACT:R-HSA-5578996
Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) REACT:R-HSA-5579014
Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) REACT:R-HSA-5579027
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) REACT:R-HSA-5579011
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) REACT:R-HSA-5579005
Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) REACT:R-HSA-5579013
Defective DHDDS causes retinitis pigmentosa 59 REACT:R-HSA-4755609
Defective DOLK causes DOLK-CDG (CDG-1m) REACT:R-HSA-4755583
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 REACT:R-HSA-4549356
Defective DPM1 causes DPM1-CDG (CDG-1e) REACT:R-HSA-4717374
Defective DPM2 causes DPM2-CDG (CDG-1u) REACT:R-HSA-4719377
Defective DPM3 causes DPM3-CDG (CDG-1o) REACT:R-HSA-4719360
Defective EXT1 causes exostoses 1, TRPS2 and CHDS REACT:R-HSA-3656253
Defective EXT2 causes exostoses 2 REACT:R-HSA-3656237
Defective FMO3 causes Trimethylaminuria (TMAU) REACT:R-HSA-5579019
Defective GALE can cause Epimerase-deficiency galactosemia (EDG) REACT:R-HSA-5609977
Defective GALK1 can cause Galactosemia II (GALCT2) REACT:R-HSA-5609976
Defective GALNT12 causes colorectal cancer 1 (CRCS1) REACT:R-HSA-5083636
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) REACT:R-HSA-5083625
Defective GALT can cause Galactosemia REACT:R-HSA-5609978
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) REACT:R-HSA-5619073
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) REACT:R-HSA-5578999
Defective GFPT1 causes CMSTA1 REACT:R-HSA-4085023
Defective GGT1 causes Glutathionuria (GLUTH) REACT:R-HSA-5579022
Defective GIF causes intrinsic factor deficiency REACT:R-HSA-3359457
Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2 REACT:R-HSA-4085011
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) REACT:R-HSA-5579006
Defective HK1 causes hexokinase deficiency (HK deficiency) REACT:R-HSA-5619056
Defective HLCS causes multiple carboxylase deficiency REACT:R-HSA-3371599
Defective LARGE causes MDDGA6 and MDDGB6 REACT:R-HSA-5083627
Defective LFNG causes SCDO3 REACT:R-HSA-5083630
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF REACT:R-HSA-3359458
Defective MAN1B1 causes MRT15 REACT:R-HSA-4793950
Defective MAOA causes Brunner syndrome (BRUNS) REACT:R-HSA-5579012
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) REACT:R-HSA-5579024
Defective MGAT2 causes MGAT2-CDG (CDG-2a) REACT:R-HSA-4793952
Defective MMAA causes methylmalonic aciduria type cblA REACT:R-HSA-3359475
Defective MMAB causes methylmalonic aciduria type cblB REACT:R-HSA-3359471
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC REACT:R-HSA-3359474
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD REACT:R-HSA-3359473
Defective MOGS causes MOGS-CDG (CDG-2b) REACT:R-HSA-4793954
Defective MPDU1 causes MPDU1-CDG (CDG-1f) REACT:R-HSA-4687000
Defective MPI causes MPI-CDG (CDG-1b) REACT:R-HSA-4043916
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG REACT:R-HSA-3359469
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE REACT:R-HSA-3359467
Defective MUT causes methylmalonic aciduria mut type REACT:R-HSA-3359478
Defective NEU1 causes sialidosis REACT:R-HSA-4341670
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) REACT:R-HSA-5578998
Defective PAPSS2 causes SEMD-PA REACT:R-HSA-3560796
Defective PGM1 causes PGM1-CDG (CDG1t) REACT:R-HSA-5609974
Defective PMM2 causes PMM2-CDG (CDG-1a) REACT:R-HSA-4043911
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 REACT:R-HSA-5083628
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 REACT:R-HSA-5083633
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 REACT:R-HSA-5083629
Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) REACT:R-HSA-5688031
Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) REACT:R-HSA-5688354
Defective RFT1 causes RFT1-CDG (CDG-1n) REACT:R-HSA-4570571
Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN) REACT:R-HSA-5619042
Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF) REACT:R-HSA-5687868
Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) REACT:R-HSA-5619048
Defective SLC12A1 causes Bartter syndrome 1 (BS1) REACT:R-HSA-5619104
Defective SLC12A3 causes Gitelman syndrome (GS) REACT:R-HSA-5619087
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) REACT:R-HSA-5619039
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) REACT:R-HSA-5619070
Defective SLC17A5 causes Salla disease (SD) and ISSD REACT:R-HSA-5619035
Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) REACT:R-HSA-5619076
Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) REACT:R-HSA-5619067
Defective SLC1A3 causes episodic ataxia 6 (EA6) REACT:R-HSA-5619062
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) REACT:R-HSA-5619111
Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) REACT:R-HSA-5619071
Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) REACT:R-HSA-5619066
Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) REACT:R-HSA-5619053
Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) REACT:R-HSA-5619077
Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) REACT:R-HSA-5619055
Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) REACT:R-HSA-5619036
Defective SLC26A2 causes chondrodysplasias REACT:R-HSA-3560792
Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1) REACT:R-HSA-5619085
Defective SLC26A4 causes Pendred syndrome (PDS) REACT:R-HSA-5619046
Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) REACT:R-HSA-5619108
Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS) REACT:R-HSA-5619063
Defective SLC2A10 causes arterial tortuosity syndrome (ATS) REACT:R-HSA-5619068
Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) REACT:R-HSA-5619043
Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) REACT:R-HSA-5619098
Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) REACT:R-HSA-5619047
Defective SLC33A1 causes spastic paraplegia 42 (SPG42) REACT:R-HSA-5619061
Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) REACT:R-HSA-5619040
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5619045
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5687583
Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) REACT:R-HSA-5619097
Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5619037
Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5663020
Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) REACT:R-HSA-5619072
Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) REACT:R-HSA-5619083
Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) REACT:R-HSA-5619078
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) REACT:R-HSA-5579020
Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG) REACT:R-HSA-5619041
Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ) REACT:R-HSA-5619088
Defective SLC3A1 causes cystinuria (CSNU) REACT:R-HSA-5619113
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) REACT:R-HSA-5655799
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) REACT:R-HSA-5619049
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) REACT:R-HSA-5619050
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) REACT:R-HSA-5619054
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) REACT:R-HSA-5656364
Defective SLC5A2 causes renal glucosuria (GLYS1) REACT:R-HSA-5658208
Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) REACT:R-HSA-5619096
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5619114
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5658471
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5619079
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5659729
Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5619044
Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5659735
Defective SLC6A2 causes orthostatic intolerance (OI) REACT:R-HSA-5619109
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5619081
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5660724
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) REACT:R-HSA-5619089
Defective SLC7A7 causes lysinuric protein intolerance (LPI) REACT:R-HSA-5660862
Defective SLC7A9 causes cystinuria (CSNU) REACT:R-HSA-5660883
Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) REACT:R-HSA-5619092
Defective SLC9A9 causes autism 16 (AUTS16) REACT:R-HSA-5619052
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619110
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5661182
Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619058
Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) REACT:R-HSA-5619095
Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ REACT:R-HSA-4755579
Defective ST3GAL3 causes MCT12 and EIEE15 REACT:R-HSA-3656243
Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) REACT:R-HSA-5579032
Defective TCN2 causes hereditary megaloblastic anemia REACT:R-HSA-3359454
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) REACT:R-HSA-5578995
Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC) REACT:R-HSA-5619107
Defective UGT1A1 causes hyperbilirubinemia REACT:R-HSA-5579002
Defective UGT1A4 causes hyperbilirubinemia REACT:R-HSA-5579016
Defects in biotin (Btn) metabolism REACT:R-HSA-3323169
Defects in cobalamin (B12) metabolism REACT:R-HSA-3296469
Defects in vitamin and cofactor metabolism REACT:R-HSA-3296482
Defensins REACT:R-HSA-1461973
Degradation of AXIN REACT:R-HSA-4641257
Degradation of beta-catenin by the destruction complex REACT:R-HSA-195253
Degradation of cysteine and homocysteine REACT:R-HSA-1614558
Degradation of DVL REACT:R-HSA-4641258
Degradation of GABA REACT:R-HSA-916853
Degradation of GLI1 by the proteasome REACT:R-HSA-5610780
Degradation of GLI2 by the proteasome REACT:R-HSA-5610783
Degradation of the extracellular matrix REACT:R-HSA-1474228
Deletions in the AMER1 gene destabilize the destruction complex REACT:R-HSA-5467343
Deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling REACT:R-HSA-5467345
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels REACT:R-HSA-112308
Depolymerisation of the Nuclear Lamina REACT:R-HSA-4419969
Deposition of new CENPA-containing nucleosomes at the centromere REACT:R-HSA-606279
Depurination REACT:R-HSA-73927
Depyrimidination REACT:R-HSA-73928
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models REACT:R-HSA-8862803
Dermatan sulfate biosynthesis REACT:R-HSA-2022923
Dermatan sulfate degradation KEGG:hsa_M00076
Detoxification of Reactive Oxygen Species REACT:R-HSA-3299685
Deubiquitination REACT:R-HSA-5688426
Developmental Biology REACT:R-HSA-1266738
DEx/H-box helicases activate type I IFN and inflammatory cytokines production REACT:R-HSA-3134963
D-Glutamine and D-glutamate metabolism KEGG:hsa00471
Digestion of dietary carbohydrate REACT:R-HSA-189085
Digestion of dietary lipid REACT:R-HSA-192456
Dilated cardiomyopathy KEGG:hsa05414
Dimerization of procaspase-8 REACT:R-HSA-69416
Disassembly of the destruction complex and recruitment of AXIN to the membrane REACT:R-HSA-4641262
Disease REACT:R-HSA-1643685
Diseases associated with glycosaminoglycan metabolism REACT:R-HSA-3560782
Diseases associated with glycosylation precursor biosynthesis REACT:R-HSA-5609975
Diseases associated with N-glycosylation of proteins REACT:R-HSA-3781860
Diseases associated with O-glycosylation of proteins REACT:R-HSA-3906995
Diseases associated with surfactant metabolism REACT:R-HSA-5687613
Diseases associated with the TLR signaling cascade REACT:R-HSA-5602358
Diseases associated with visual transduction REACT:R-HSA-2474795
Diseases of carbohydrate metabolism REACT:R-HSA-5663084
Diseases of glycosylation REACT:R-HSA-3781865
Diseases of Immune System REACT:R-HSA-5260271
Diseases of metabolism REACT:R-HSA-5668914
Diseases of signal transduction REACT:R-HSA-5663202
Disinhibition of SNARE formation REACT:R-HSA-114516
Disorders of transmembrane transporters REACT:R-HSA-5619115
Displacement of DNA glycosylase by APEX1 REACT:R-HSA-110357
Dissolution of Fibrin Clot REACT:R-HSA-75205
DNA Damage Bypass REACT:R-HSA-73893
DNA damage-induced cell cycle checkpoints KEGG:hsa_M00691
DNA Damage Recognition in GG-NER REACT:R-HSA-5696394
DNA Damage Reversal REACT:R-HSA-73942
DNA Damage/Telomere Stress Induced Senescence REACT:R-HSA-2559586
DNA Double-Strand Break Repair REACT:R-HSA-5693532
DNA Double Strand Break Response REACT:R-HSA-5693606
DNA methylation REACT:R-HSA-5334118
DNA-PK complex KEGG:hsa_M00297
DNA polymerase alpha / primase complex KEGG:hsa_M00261
DNA polymerase delta complex KEGG:hsa_M00262
DNA polymerase epsilon complex KEGG:hsa_M00263
DNA polymerase gamma complex KEGG:hsa_M00294
DNA polymerase zeta complex KEGG:hsa_M00293
DNA Repair REACT:R-HSA-73894
DNA replication KEGG:hsa03030
DNA Replication REACT:R-HSA-69306
DNA replication initiation REACT:R-HSA-68952
DNA Replication Pre-Initiation REACT:R-HSA-69002
DNA strand elongation REACT:R-HSA-69190
Dopamine clearance from the synaptic cleft REACT:R-HSA-379401
Dopamine Neurotransmitter Release Cycle REACT:R-HSA-212676
Dopamine receptors REACT:R-HSA-390651
Dopaminergic synapse KEGG:hsa04728
Dorso-ventral axis formation KEGG:hsa04320
Downregulation of ERBB2:ERBB3 signaling REACT:R-HSA-1358803
Downregulation of ERBB2 signaling REACT:R-HSA-8863795
Downregulation of ERBB4 signaling REACT:R-HSA-1253288
Downregulation of SMAD2/3:SMAD4 transcriptional activity REACT:R-HSA-2173795
Downregulation of TGF-beta receptor signaling REACT:R-HSA-2173788
Downstream signaling events of B Cell Receptor (BCR) REACT:R-HSA-1168372
Downstream signaling of activated FGFR1 REACT:R-HSA-5654687
Downstream signaling of activated FGFR2 REACT:R-HSA-5654696
Downstream signaling of activated FGFR3 REACT:R-HSA-5654708
Downstream signaling of activated FGFR4 REACT:R-HSA-5654716
Downstream signal transduction REACT:R-HSA-186763
Downstream TCR signaling REACT:R-HSA-202424
Drug metabolism - cytochrome P450 KEGG:hsa00982
Drug metabolism - other enzymes KEGG:hsa00983
DSCAM interactions REACT:R-HSA-376172
Dual Incision in GG-NER REACT:R-HSA-5696400
Dual incision in TC-NER REACT:R-HSA-6782135
E2F-enabled inhibition of pre-replication complex formation REACT:R-HSA-113507
E2F mediated regulation of DNA replication REACT:R-HSA-113510
E3 ubiquitin ligases ubiquitinate target proteins REACT:R-HSA-8866654
Early Phase of HIV Life Cycle REACT:R-HSA-162594
ECM proteoglycans REACT:R-HSA-3000178
ECM-receptor interaction KEGG:hsa04512
ECS complex KEGG:hsa_M00388
ECV complex KEGG:hsa_M00383
Effects of PIP2 hydrolysis REACT:R-HSA-114508
EGFR downregulation REACT:R-HSA-182971
EGFR interacts with phospholipase C-gamma REACT:R-HSA-212718
EGFR Transactivation by Gastrin REACT:R-HSA-2179392
EGFR tyrosine kinase inhibitor resistance KEGG:hsa01521
Eicosanoid ligand-binding receptors REACT:R-HSA-391903
Eicosanoids REACT:R-HSA-211979
eIF4F complex KEGG:hsa_M00428
Elastic fibre formation REACT:R-HSA-1566948
Electric Transmission Across Gap Junctions REACT:R-HSA-112303
Electron transport from NADPH to Ferredoxin REACT:R-HSA-2395516
Elevation of cytosolic Ca2+ levels REACT:R-HSA-139853
Endocrine and other factor-regulated calcium reabsorption KEGG:hsa04961
Endocrine resistance KEGG:hsa01522
Endocytosis KEGG:hsa04144
Endogenous sterols REACT:R-HSA-211976
Endometrial cancer KEGG:hsa05213
Endosomal Sorting Complex Required For Transport (ESCRT) REACT:R-HSA-917729
Endosomal/Vacuolar pathway REACT:R-HSA-1236977
Energy dependent regulation of mTOR by LKB1-AMPK REACT:R-HSA-380972
eNOS activation REACT:R-HSA-203615
eNOS activation and regulation REACT:R-HSA-203765
Entry of Influenza Virion into Host Cell via Endocytosis REACT:R-HSA-168275
Enzymatic degradation of dopamine by COMT REACT:R-HSA-379397
Enzymatic degradation of Dopamine by monoamine oxidase REACT:R-HSA-379398
EPHA-mediated growth cone collapse REACT:R-HSA-3928663
EPHB-mediated forward signaling REACT:R-HSA-3928662
EPH-ephrin mediated repulsion of cells REACT:R-HSA-3928665
EPH-Ephrin signaling REACT:R-HSA-2682334
Ephrin signaling REACT:R-HSA-3928664
Epigenetic regulation of gene expression REACT:R-HSA-212165
Epithelial cell signaling in Helicobacter pylori infection KEGG:hsa05120
Epstein-Barr virus infection KEGG:hsa05169
ERBB2 Activates PTK6 Signaling REACT:R-HSA-8847993
ERBB2 Regulates Cell Motility REACT:R-HSA-6785631
ErbB signaling pathway KEGG:hsa04012
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression REACT:R-HSA-427389
ERK/MAPK targets REACT:R-HSA-198753
ERKs are inactivated REACT:R-HSA-202670
ER-Phagosome pathway REACT:R-HSA-1236974
ER Quality Control Compartment (ERQC) REACT:R-HSA-901032
ER to Golgi Anterograde Transport REACT:R-HSA-199977
Erythrocytes take up carbon dioxide and release oxygen REACT:R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide REACT:R-HSA-1247673
ESCRT-0 complex KEGG:hsa_M00408
ESCRT-I complex KEGG:hsa_M00409
ESCRT-II complex KEGG:hsa_M00410
ESCRT-III complex KEGG:hsa_M00412
Essential fructosuria REACT:R-HSA-5657562
Essential pentosuria REACT:R-HSA-5662853
Establishment of Sister Chromatid Cohesion REACT:R-HSA-2468052
Estrogen biosynthesis REACT:R-HSA-193144
Estrogen signaling pathway KEGG:hsa04915
Ethanol oxidation REACT:R-HSA-71384
Ether lipid metabolism KEGG:hsa00565
Eukaryotic Translation Elongation REACT:R-HSA-156842
Eukaryotic Translation Initiation REACT:R-HSA-72613
Eukaryotic Translation Termination REACT:R-HSA-72764
Exon junction complex (EJC) KEGG:hsa_M00430
Exosome, archaea KEGG:hsa_M00390
Exosome, eukaryotes KEGG:hsa_M00391
Export of Viral Ribonucleoproteins from Nucleus REACT:R-HSA-168274
Extension of Telomeres REACT:R-HSA-180786
Extracellular matrix organization REACT:R-HSA-1474244
Extrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140834
Facilitative Na+-independent glucose transporters REACT:R-HSA-428790
FA core complex KEGG:hsa_M00413
Factors involved in megakaryocyte development and platelet production REACT:R-HSA-983231
Fanconi anemia pathway KEGG:hsa03460
Fanconi Anemia Pathway REACT:R-HSA-6783310
FasL/ CD95L signaling REACT:R-HSA-75157
Fat digestion and absorption KEGG:hsa04975
Fatty acid biosynthesis KEGG:hsa00061
Fatty acid biosynthesis, elongation KEGG:hsa_M00083
Fatty acid biosynthesis, elongation, endoplasmic reticulum KEGG:hsa_M00415
Fatty acid biosynthesis, elongation, mitochondria KEGG:hsa_M00085
Fatty acid biosynthesis, initiation KEGG:hsa_M00082
Fatty acid degradation KEGG:hsa00071
Fatty acid elongation KEGG:hsa00062
Fatty acid metabolism KEGG:hsa01212
Fatty acids REACT:R-HSA-211935
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion REACT:R-HSA-434316
Fatty acid, triacylglycerol, and ketone body metabolism REACT:R-HSA-535734
Fatty Acyl-CoA Biosynthesis REACT:R-HSA-75105
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis REACT:R-HSA-8854050
FBXW7 Mutants and NOTCH1 in Cancer REACT:R-HSA-2644605
Fc epsilon receptor (FCERI) signaling REACT:R-HSA-2454202
Fc epsilon RI signaling pathway KEGG:hsa04664
FCERI mediated Ca+2 mobilization REACT:R-HSA-2871809
FCERI mediated MAPK activation REACT:R-HSA-2871796
FCERI mediated NF-kB activation REACT:R-HSA-2871837
Fcgamma receptor (FCGR) dependent phagocytosis REACT:R-HSA-2029480
Fc gamma R-mediated phagocytosis KEGG:hsa04666
FCGR activation REACT:R-HSA-2029481
Ferroptosis KEGG:hsa04216
Fertilization REACT:R-HSA-1187000
FGFR1b ligand binding and activation REACT:R-HSA-190370
FGFR1c and Klotho ligand binding and activation REACT:R-HSA-190374
FGFR1c ligand binding and activation REACT:R-HSA-190373
FGFR1 ligand binding and activation REACT:R-HSA-190242
FGFR1 mutant receptor activation REACT:R-HSA-1839124
FGFR2 alternative splicing REACT:R-HSA-6803529
FGFR2b ligand binding and activation REACT:R-HSA-190377
FGFR2c ligand binding and activation REACT:R-HSA-190375
FGFR2 ligand binding and activation REACT:R-HSA-190241
FGFR2 mutant receptor activation REACT:R-HSA-1839126
FGFR3b ligand binding and activation REACT:R-HSA-190371
FGFR3c ligand binding and activation REACT:R-HSA-190372
FGFR3 ligand binding and activation REACT:R-HSA-190239
FGFR3 mutant receptor activation REACT:R-HSA-2033514
FGFR4 ligand binding and activation REACT:R-HSA-190322
FGFR4 mutant receptor activation REACT:R-HSA-1839128
FGFRL1 modulation of FGFR1 signaling REACT:R-HSA-5658623
Fibronectin matrix formation REACT:R-HSA-1566977
Ficolins bind to repetitive carbohydrate structures on the target cell surface REACT:R-HSA-2855086
Fluid shear stress and atherosclerosis KEGG:hsa05418
FMO oxidises nucleophiles REACT:R-HSA-217271
Focal adhesion KEGG:hsa04510
Folate biosynthesis KEGG:hsa00790
Folding of actin by CCT/TriC REACT:R-HSA-390450
Formation of annular gap junctions REACT:R-HSA-196025
Formation of a pool of free 40S subunits REACT:R-HSA-72689
Formation of apoptosome REACT:R-HSA-111458
Formation of ATP by chemiosmotic coupling REACT:R-HSA-163210
Formation of editosomes by ADAR proteins REACT:R-HSA-77042
Formation of Fibrin Clot (Clotting Cascade) REACT:R-HSA-140877
Formation of HIV-1 elongation complex containing HIV-1 Tat REACT:R-HSA-167200
Formation of HIV elongation complex in the absence of HIV Tat REACT:R-HSA-167152
Formation of Incision Complex in GG-NER REACT:R-HSA-5696395
Formation of RNA Pol II elongation complex REACT:R-HSA-112382
Formation of selenosugars for excretion REACT:R-HSA-2408499
Formation of Senescence-Associated Heterochromatin Foci (SAHF) REACT:R-HSA-2559584
Formation of TC-NER Pre-Incision Complex REACT:R-HSA-6781823
Formation of the active cofactor, UDP-glucuronate REACT:R-HSA-173599
Formation of the beta-catenin:TCF transactivating complex REACT:R-HSA-201722
Formation of the cornified envelope REACT:R-HSA-6809371
Formation of the Early Elongation Complex REACT:R-HSA-113418
Formation of the Editosome REACT:R-HSA-75094
Formation of the HIV-1 Early Elongation Complex REACT:R-HSA-167158
Formation of the ternary complex, and subsequently, the 43S complex REACT:R-HSA-72695
Formation of tubulin folding intermediates by CCT/TriC REACT:R-HSA-389960
Formyl peptide receptors bind formyl peptides and many other ligands REACT:R-HSA-444473
FoxO signaling pathway KEGG:hsa04068
Free fatty acid receptors REACT:R-HSA-444209
Free fatty acids regulate insulin secretion REACT:R-HSA-400451
Frs2-mediated activation REACT:R-HSA-170968
FRS-mediated FGFR1 signaling REACT:R-HSA-5654693
FRS-mediated FGFR2 signaling REACT:R-HSA-5654700
FRS-mediated FGFR3 signaling REACT:R-HSA-5654706
FRS-mediated FGFR4 signaling REACT:R-HSA-5654712
Fructose and mannose metabolism KEGG:hsa00051
Fructose biosynthesis REACT:R-HSA-5652227
Fructose catabolism REACT:R-HSA-70350
Fructose metabolism REACT:R-HSA-5652084
F-type ATPase, eukaryotes KEGG:hsa_M00158
Fusion and Uncoating of the Influenza Virion REACT:R-HSA-168270
Fusion of the Influenza Virion to the Host Cell Endosome REACT:R-HSA-168288
G0 and Early G1 REACT:R-HSA-1538133
G1 Phase REACT:R-HSA-69236
G1/S DNA Damage Checkpoints REACT:R-HSA-69615
G1/S-Specific Transcription REACT:R-HSA-69205
G1/S Transition REACT:R-HSA-69206
G2/M Checkpoints REACT:R-HSA-69481
G2/M DNA damage checkpoint REACT:R-HSA-69473
G2/M DNA replication checkpoint REACT:R-HSA-69478
G2/M Transition REACT:R-HSA-69275
G2 Phase REACT:R-HSA-68911
GAB1 signalosome REACT:R-HSA-180292
GABA A receptor activation REACT:R-HSA-977441
GABA A (rho) receptor activation REACT:R-HSA-977442
GABA biosynthesis, eukaryotes, putrescine => GABA KEGG:hsa_M00135
GABA B receptor activation REACT:R-HSA-977444
GABAergic synapse KEGG:hsa04727
GABA (gamma-Aminobutyrate) shunt KEGG:hsa_M00027
GABA receptor activation REACT:R-HSA-977443
GABA synthesis REACT:R-HSA-888568
GABA synthesis, release, reuptake and degradation REACT:R-HSA-888590
Galactose catabolism REACT:R-HSA-70370
Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P KEGG:hsa_M00632
Galactose metabolism KEGG:hsa00052
G alpha (12/13) signalling events REACT:R-HSA-416482
G alpha (i) signalling events REACT:R-HSA-418594
G alpha (q) signalling events REACT:R-HSA-416476
G alpha (s) signalling events REACT:R-HSA-418555
G alpha (z) signalling events REACT:R-HSA-418597
Gamma carboxylation, hypusine formation and arylsulfatase activation REACT:R-HSA-163841
Gamma-carboxylation of protein precursors REACT:R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins REACT:R-HSA-159854
Gap-filling DNA repair synthesis and ligation in GG-NER REACT:R-HSA-5696397
Gap-filling DNA repair synthesis and ligation in TC-NER REACT:R-HSA-6782210
Gap junction KEGG:hsa04540
Gap junction assembly REACT:R-HSA-190861
Gap junction degradation REACT:R-HSA-190873
Gap junction trafficking REACT:R-HSA-190828
Gap junction trafficking and regulation REACT:R-HSA-157858
Gastric acid secretion KEGG:hsa04971
Gastrin-CREB signalling pathway via PKC and MAPK REACT:R-HSA-881907
G beta:gamma signalling through PI3Kgamma REACT:R-HSA-392451
G beta:gamma signalling through PLC beta REACT:R-HSA-418217
GDP-fucose biosynthesis REACT:R-HSA-6787639
Gene Expression REACT:R-HSA-74160
Generation of second messenger molecules REACT:R-HSA-202433
Generic Transcription Pathway REACT:R-HSA-212436
Gene Silencing by RNA REACT:R-HSA-211000
GINS complex KEGG:hsa_M00286
GLI3 is processed to GLI3R by the proteasome REACT:R-HSA-5610785
Glioma KEGG:hsa05214
GLI proteins bind promoters of Hh responsive genes to promote transcription REACT:R-HSA-5635851
Global Genome Nucleotide Excision Repair (GG-NER) REACT:R-HSA-5696399
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion REACT:R-HSA-381676
Glucagon signaling in metabolic regulation REACT:R-HSA-163359
Glucagon signaling pathway KEGG:hsa04922
Glucagon-type ligand receptors REACT:R-HSA-420092
Glucocorticoid biosynthesis REACT:R-HSA-194002
Gluconeogenesis REACT:R-HSA-70263
Gluconeogenesis, oxaloacetate => fructose-6P KEGG:hsa_M00003
Glucose metabolism REACT:R-HSA-70326
Glucose transport REACT:R-HSA-70153
Glucuronate pathway (uronate pathway) KEGG:hsa_M00014
Glucuronidation REACT:R-HSA-156588
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity REACT:R-HSA-399721
Glutamate Neurotransmitter Release Cycle REACT:R-HSA-210500
Glutamatergic synapse KEGG:hsa04724
Glutathione biosynthesis, glutamate => glutathione KEGG:hsa_M00118
Glutathione conjugation REACT:R-HSA-156590
Glutathione metabolism KEGG:hsa00480
Glutathione synthesis and recycling REACT:R-HSA-174403
Glycerolipid metabolism KEGG:hsa00561
Glycerophospholipid biosynthesis REACT:R-HSA-1483206
Glycerophospholipid catabolism REACT:R-HSA-6814848
Glycerophospholipid metabolism KEGG:hsa00564
Glycine degradation REACT:R-HSA-6783984
Glycine, serine and threonine metabolism KEGG:hsa00260
Glycogen breakdown (glycogenolysis) REACT:R-HSA-70221
Glycogen storage diseases REACT:R-HSA-3229121
Glycogen storage disease type 0 (liver GYS2) REACT:R-HSA-3858516
Glycogen storage disease type 0 (muscle GYS1) REACT:R-HSA-3828062
Glycogen storage disease type Ia (G6PC) REACT:R-HSA-3274531
Glycogen storage disease type Ib (SLC37A4) REACT:R-HSA-3229133
Glycogen storage disease type II (GAA) REACT:R-HSA-5357609
Glycogen storage disease type IV (GBE1) REACT:R-HSA-3878781
Glycogen storage disease type XV (GYG1) REACT:R-HSA-3814836
Glycogen synthesis REACT:R-HSA-3322077
Glycolysis REACT:R-HSA-70171
Glycolysis, core module involving three-carbon compounds KEGG:hsa_M00002
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate KEGG:hsa_M00001
Glycolysis / Gluconeogenesis KEGG:hsa00010
Glycoprotein hormones REACT:R-HSA-209822
Glycosaminoglycan biosynthesis, chondroitin sulfate backbone KEGG:hsa_M00058
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate KEGG:hsa00532
Glycosaminoglycan biosynthesis, heparan sulfate backbone KEGG:hsa_M00059
Glycosaminoglycan biosynthesis - heparan sulfate / heparin KEGG:hsa00534
Glycosaminoglycan biosynthesis - keratan sulfate KEGG:hsa00533
Glycosaminoglycan biosynthesis, linkage tetrasaccharide KEGG:hsa_M00057
Glycosaminoglycan degradation KEGG:hsa00531
Glycosaminoglycan metabolism REACT:R-HSA-1630316
Glycosphingolipid biosynthesis - ganglio series KEGG:hsa00604
Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 KEGG:hsa_M00069
Glycosphingolipid biosynthesis - globo and isoglobo series KEGG:hsa00603
Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer KEGG:hsa_M00068
Glycosphingolipid biosynthesis - lacto and neolacto series KEGG:hsa00601
Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer KEGG:hsa_M00070
Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer KEGG:hsa_M00071
Glycosphingolipid metabolism REACT:R-HSA-1660662
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis KEGG:hsa00563
Glyoxylate and dicarboxylate metabolism KEGG:hsa00630
Glyoxylate metabolism and glycine degradation REACT:R-HSA-389661
GnRH signaling pathway KEGG:hsa04912
Golgi Associated Vesicle Biogenesis REACT:R-HSA-432722
Golgi Cisternae Pericentriolar Stack Reorganization REACT:R-HSA-162658
Golgi-to-ER retrograde transport REACT:R-HSA-8856688
GP1b-IX-V activation signalling REACT:R-HSA-430116
GPCR downstream signaling REACT:R-HSA-388396
GPCR ligand binding REACT:R-HSA-500792
GPI-anchor biosynthesis, core oligosaccharide KEGG:hsa_M00065
G-protein activation REACT:R-HSA-202040
G-protein beta:gamma signalling REACT:R-HSA-397795
G protein gated Potassium channels REACT:R-HSA-1296059
G-protein mediated events REACT:R-HSA-112040
GPVI-mediated activation cascade REACT:R-HSA-114604
Graft-versus-host disease KEGG:hsa05332
GRB2 events in EGFR signaling REACT:R-HSA-179812
GRB2 events in ERBB2 signaling REACT:R-HSA-1963640
GRB2:SOS provides linkage to MAPK signaling for Integrins REACT:R-HSA-354194
GRB7 events in ERBB2 signaling REACT:R-HSA-1306955
Growth hormone receptor signaling REACT:R-HSA-982772
GTP hydrolysis and joining of the 60S ribosomal subunit REACT:R-HSA-72706
Guanine ribonucleotide biosynthesis IMP => GDP,GTP KEGG:hsa_M00050
H/ACA ribonucleoprotein complex KEGG:hsa_M00425
HATs acetylate histones REACT:R-HSA-3214847
HCN channels REACT:R-HSA-1296061
HDACs deacetylate histones REACT:R-HSA-3214815
HDL-mediated lipid transport REACT:R-HSA-194223
HDMs demethylate histones REACT:R-HSA-3214842
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) REACT:R-HSA-5693567
HDR through Homologous Recombination (HRR) REACT:R-HSA-5685942
HDR through MMEJ (alt-NHEJ) REACT:R-HSA-5685939
HDR through Single Strand Annealing (SSA) REACT:R-HSA-5685938
Hedgehog ligand biogenesis REACT:R-HSA-5358346
Hedgehog 'off' state REACT:R-HSA-5610787
Hedgehog 'on' state REACT:R-HSA-5632684
Hedgehog signaling KEGG:hsa_M00678
Hedgehog signaling pathway KEGG:hsa04340
Hematopoietic cell lineage KEGG:hsa04640
Heme biosynthesis REACT:R-HSA-189451
Heme degradation REACT:R-HSA-189483
Hemostasis REACT:R-HSA-109582
Heparan sulfate degradation KEGG:hsa_M00078
Heparan sulfate/heparin (HS-GAG) metabolism REACT:R-HSA-1638091
Hepatitis B KEGG:hsa05161
Hepatitis C KEGG:hsa05160
Hereditary fructose intolerance REACT:R-HSA-5657560
Herpes simplex infection KEGG:hsa05168
Hexose transport REACT:R-HSA-189200
HHAT G278V abrogates palmitoylation of Hh-Np REACT:R-HSA-5658034
Hh mutants abrogate ligand secretion REACT:R-HSA-5387390
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD REACT:R-HSA-5362768
HIF-1 signaling pathway KEGG:hsa04066
Highly calcium permeable nicotinic acetylcholine receptors REACT:R-HSA-629597
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-629594
Highly sodium permeable acetylcholine nicotinic receptors REACT:R-HSA-629587
Hippo signaling KEGG:hsa_M00683
Hippo signaling pathway KEGG:hsa04390
Hippo signaling pathway -multiple species KEGG:hsa04392
Histamine receptors REACT:R-HSA-390650
Histidine catabolism REACT:R-HSA-70921
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism REACT:R-HSA-6788656
Histidine metabolism KEGG:hsa00340
HIV elongation arrest and recovery REACT:R-HSA-167287
HIV Infection REACT:R-HSA-162906
HIV Life Cycle REACT:R-HSA-162587
HIV Transcription Elongation REACT:R-HSA-167169
HIV Transcription Initiation REACT:R-HSA-167161
Holo-TFIIH complex KEGG:hsa_M00290
Homologous DNA Pairing and Strand Exchange REACT:R-HSA-5693579
Homologous recombination KEGG:hsa03440
Homology Directed Repair REACT:R-HSA-5693538
Hormone ligand-binding receptors REACT:R-HSA-375281
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis REACT:R-HSA-163560
Host Interactions of HIV factors REACT:R-HSA-162909
Host Interactions with Influenza Factors REACT:R-HSA-168253
HRD1/SEL1 ERAD complex KEGG:hsa_M00403
HSF1 activation REACT:R-HSA-3371511
HSF1-dependent transactivation REACT:R-HSA-3371571
HS-GAG biosynthesis REACT:R-HSA-2022928
HS-GAG degradation REACT:R-HSA-2024096
HTLV-I infection KEGG:hsa05166
Huntington's disease KEGG:hsa05016
HuR (ELAVL1) binds and stabilizes mRNA REACT:R-HSA-450520
Hyaluronan biosynthesis and export REACT:R-HSA-2142850
Hyaluronan metabolism REACT:R-HSA-2142845
Hyaluronan uptake and degradation REACT:R-HSA-2160916
Hydrolysis of LPC REACT:R-HSA-1483115
Hydrolysis of LPE REACT:R-HSA-1483152
Hydroxycarboxylic acid-binding receptors REACT:R-HSA-3296197
Hypertrophic cardiomyopathy (HCM) KEGG:hsa05410
Hypusine synthesis from eIF5A-lysine REACT:R-HSA-204626
IGF1R signaling cascade REACT:R-HSA-2428924
IkBA variant leads to EDA-ID REACT:R-HSA-5603029
IKBKB deficiency causes SCID REACT:R-HSA-5602636
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) REACT:R-HSA-5603027
IKK complex recruitment mediated by RIP1 REACT:R-HSA-937041
IL-17 signaling pathway KEGG:hsa04657
IL-6-type cytokine receptor ligand interactions REACT:R-HSA-6788467
Immune System REACT:R-HSA-168256
Immunoproteasome KEGG:hsa_M00337
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell REACT:R-HSA-198933
Import of palmitoyl-CoA into the mitochondrial matrix REACT:R-HSA-200425
Inactivation of APC/C via direct inhibition of the APC/C complex REACT:R-HSA-141430
Inactivation of Cdc42 and Rac REACT:R-HSA-428543
Inactivation, recovery and regulation of the phototransduction cascade REACT:R-HSA-2514859
Incretin synthesis, secretion, and inactivation REACT:R-HSA-400508
Infectious disease REACT:R-HSA-5663205
Inflammasomes REACT:R-HSA-622312
Inflammatory bowel disease (IBD) KEGG:hsa05321
Inflammatory mediator regulation of TRP channels KEGG:hsa04750
Influenza A KEGG:hsa05164
Influenza Infection REACT:R-HSA-168254
Influenza Life Cycle REACT:R-HSA-168255
Influenza Viral RNA Transcription and Replication REACT:R-HSA-168273
Influenza Virus Induced Apoptosis REACT:R-HSA-168277
Inhibition of adenylate cyclase pathway REACT:R-HSA-997269
Inhibition of Host mRNA Processing and RNA Silencing REACT:R-HSA-168315
Inhibition of IFN-beta REACT:R-HSA-168888
Inhibition of Interferon Synthesis REACT:R-HSA-168305
Inhibition of PKR REACT:R-HSA-169131
Inhibition of replication initiation of damaged DNA by RB1/E2F1 REACT:R-HSA-113501
Inhibition of Signaling by Overexpressed EGFR REACT:R-HSA-5638303
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components REACT:R-HSA-141405
Inhibition of TSC complex formation by PKB REACT:R-HSA-165181
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits REACT:R-HSA-997272
Initial triggering of complement REACT:R-HSA-166663
Initiation of Nuclear Envelope Reformation REACT:R-HSA-2995383
InlA-mediated entry of Listeria monocytogenes into host cells REACT:R-HSA-8876493
InlB-mediated entry of Listeria monocytogenes into host cell REACT:R-HSA-8875360
Innate Immune System REACT:R-HSA-168249
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP KEGG:hsa_M00048
Inositol phosphate metabolism KEGG:hsa00562
Inositol phosphate metabolism REACT:R-HSA-1483249
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol KEGG:hsa_M00131
Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate KEGG:hsa_M00132
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 KEGG:hsa_M00130
Inositol transporters REACT:R-HSA-429593
Insulin effects increased synthesis of Xylulose-5-Phosphate REACT:R-HSA-163754
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA REACT:R-HSA-428359
Insulin processing REACT:R-HSA-264876
Insulin receptor recycling REACT:R-HSA-77387
Insulin receptor signalling cascade REACT:R-HSA-74751
Insulin resistance KEGG:hsa04931
Insulin secretion KEGG:hsa04911
Insulin signaling pathway KEGG:hsa04910
Integration of energy metabolism REACT:R-HSA-163685
Integration of provirus REACT:R-HSA-162592
Integration of viral DNA into host genomic DNA REACT:R-HSA-175567
Integrin alphaIIb beta3 signaling REACT:R-HSA-354192
Integrin cell surface interactions REACT:R-HSA-216083
Interaction between L1 and Ankyrins REACT:R-HSA-445095
Interaction between PHLDA1 and AURKA REACT:R-HSA-8854521
Interactions of neurexins and neuroligins at synapses REACT:R-HSA-6794361
Interactions of Rev with host cellular proteins REACT:R-HSA-177243
Interactions of Tat with host cellular proteins REACT:R-HSA-176034
Interactions of Vpr with host cellular proteins REACT:R-HSA-176033
Interaction With Cumulus Cells REACT:R-HSA-2534343
Interaction With The Zona Pellucida REACT:R-HSA-1300644
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate REACT:R-HSA-880009
Interconversion of polyamines REACT:R-HSA-351200
Interferon alpha/beta signaling REACT:R-HSA-909733
Interferon gamma signaling REACT:R-HSA-877300
Interferon Signaling REACT:R-HSA-913531
Interleukin-10 signaling REACT:R-HSA-6783783
Interleukin-12 signaling REACT:R-HSA-447115
Interleukin-17 signaling REACT:R-HSA-448424
Interleukin-19, 20, 22, 24 REACT:R-HSA-8854691
Interleukin-1 processing REACT:R-HSA-448706
Interleukin-1 signaling REACT:R-HSA-446652
Interleukin-2 signaling REACT:R-HSA-451927
Interleukin-3, 5 and GM-CSF signaling REACT:R-HSA-512988
Interleukin-4 and 13 signaling REACT:R-HSA-6785807
Interleukin-6 family signaling REACT:R-HSA-6783589
Interleukin-6 signaling REACT:R-HSA-1059683
Interleukin-7 signaling REACT:R-HSA-1266695
Interleukin receptor SHC signaling REACT:R-HSA-912526
Intestinal immune network for IgA production KEGG:hsa04672
Intestinal infectious diseases REACT:R-HSA-8942233
Intestinal saccharidase deficiencies REACT:R-HSA-5659898
Intraflagellar transport REACT:R-HSA-5620924
Intra-Golgi and retrograde Golgi-to-ER traffic REACT:R-HSA-6811442
Intra-Golgi traffic REACT:R-HSA-6811438
Intrinsic Pathway for Apoptosis REACT:R-HSA-109606
Intrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140837
Inwardly rectifying K+ channels REACT:R-HSA-1296065
Ion channel transport REACT:R-HSA-983712
Ion homeostasis REACT:R-HSA-5578775
Ion influx/efflux at host-pathogen interface REACT:R-HSA-6803544
Ionotropic activity of Kainate Receptors REACT:R-HSA-451306
Ion transport by P-type ATPases REACT:R-HSA-936837
IP3 and IP4 transport between cytosol and nucleus REACT:R-HSA-1855196
IP6 and IP7 transport between cytosol and nucleus REACT:R-HSA-1855229
IPs transport between cytosol and ER lumen REACT:R-HSA-1855184
IPs transport between ER lumen and cytosol REACT:R-HSA-1855215
IPs transport between ER lumen and nucleus REACT:R-HSA-1855156
IPs transport between nucleus and cytosol REACT:R-HSA-1855170
IPs transport between nucleus and ER lumen REACT:R-HSA-1855192
IRAK1 recruits IKK complex REACT:R-HSA-937039
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975144
IRAK2 mediated activation of TAK1 complex REACT:R-HSA-937042
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975163
IRAK4 deficiency (TLR2/4) REACT:R-HSA-5603041
IRAK4 deficiency (TLR5) REACT:R-HSA-5603037
IRE1alpha activates chaperones REACT:R-HSA-381070
IRF3 mediated activation of type 1 IFN REACT:R-HSA-1606341
IRF3-mediated induction of type I IFN REACT:R-HSA-3270619
Iron uptake and transport REACT:R-HSA-917937
IRS activation REACT:R-HSA-74713
IRS-mediated signalling REACT:R-HSA-112399
IRS-related events triggered by IGF1R REACT:R-HSA-2428928
ISG15 antiviral mechanism REACT:R-HSA-1169408
JAK-STAT signaling KEGG:hsa_M00684
Jak-STAT signaling pathway KEGG:hsa04630
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 REACT:R-HSA-450321
Josephin domain DUBs REACT:R-HSA-5689877
Keratan sulfate biosynthesis REACT:R-HSA-2022854
Keratan sulfate degradation KEGG:hsa_M00079
Keratan sulfate degradation REACT:R-HSA-2022857
Keratan sulfate/keratin metabolism REACT:R-HSA-1638074
Keratinization REACT:R-HSA-6805567
Ketone body metabolism REACT:R-HSA-74182
Kinesins REACT:R-HSA-983189
KSRP (KHSRP) binds and destabilizes mRNA REACT:R-HSA-450604
L13a-mediated translational silencing of Ceruloplasmin expression REACT:R-HSA-156827
L1CAM interactions REACT:R-HSA-373760
Lactose synthesis REACT:R-HSA-5653890
Lactosylceramide biosynthesis KEGG:hsa_M00066
Lagging Strand Synthesis REACT:R-HSA-69186
Laminin interactions REACT:R-HSA-3000157
Latent infection of Homo sapiens with Mycobacterium tuberculosis REACT:R-HSA-1222352
Late Phase of HIV Life Cycle REACT:R-HSA-162599
LDL-mediated lipid transport REACT:R-HSA-171052
Leading Strand Synthesis REACT:R-HSA-69109
Lectin pathway of complement activation REACT:R-HSA-166662
Legionellosis KEGG:hsa05134
Leishmaniasis KEGG:hsa05140
Leucine degradation, leucine => acetoacetate + acetyl-CoA KEGG:hsa_M00036
Leukocyte transendothelial migration KEGG:hsa04670
Leukotriene receptors REACT:R-HSA-391906
LGI-ADAM interactions REACT:R-HSA-5682910
Ligand-dependent caspase activation REACT:R-HSA-140534
Ligand-gated ion channel transport REACT:R-HSA-975298
Ligand-independent caspase activation via DCC REACT:R-HSA-418889
Ligand-receptor interactions REACT:R-HSA-5632681
Linoleic acid (LA) metabolism REACT:R-HSA-2046105
Linoleic acid metabolism KEGG:hsa00591
Lipid digestion, mobilization, and transport REACT:R-HSA-73923
Lipoic acid metabolism KEGG:hsa00785
Lipoprotein metabolism REACT:R-HSA-174824
Listeria monocytogenes entry into host cells REACT:R-HSA-8876384
Localization of the PINCH-ILK-PARVIN complex to focal adhesions REACT:R-HSA-446343
Longevity regulating pathway KEGG:hsa04211
Longevity regulating pathway - multiple species KEGG:hsa04213
Long-term depression KEGG:hsa04730
Long-term potentiation KEGG:hsa04720
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling REACT:R-HSA-2644607
Loss of Function of SMAD2/3 in Cancer REACT:R-HSA-3304349
Loss of Function of SMAD4 in Cancer REACT:R-HSA-3304347
Loss of Function of TGFBR1 in Cancer REACT:R-HSA-3656534
Loss of Function of TGFBR2 in Cancer REACT:R-HSA-3642278
Loss of Nlp from mitotic centrosomes REACT:R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome REACT:R-HSA-380284
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production REACT:R-HSA-3134973
Lsm 1-7 complex KEGG:hsa_M00397
Lsm 2-8 complex KEGG:hsa_M00396
Lysine biosynthesis KEGG:hsa00300
Lysine catabolism REACT:R-HSA-71064
Lysine degradation KEGG:hsa00310
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA KEGG:hsa_M00032
Lysosomal glycogen catabolism REACT:R-HSA-5357572
Lysosomal oligosaccharide catabolism REACT:R-HSA-8853383
Lysosome KEGG:hsa04142
Lysosome Vesicle Biogenesis REACT:R-HSA-432720
Lysosphingolipid and LPA receptors REACT:R-HSA-419408
Macroautophagy REACT:R-HSA-1632852
Major pathway of rRNA processing in the nucleolus and cytosol REACT:R-HSA-6791226
Malaria KEGG:hsa05144
Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA KEGG:hsa_M00013
Mannose type O-glycan biosynthesis KEGG:hsa00515
MAP2K and MAPK activation REACT:R-HSA-5674135
MAP3K8 (TPL2)-dependent MAPK1/3 activation REACT:R-HSA-5684264
MAPK1 (ERK2) activation REACT:R-HSA-112411
MAPK1/MAPK3 signaling REACT:R-HSA-5684996
MAPK3 (ERK1) activation REACT:R-HSA-110056
MAPK6/MAPK4 signaling REACT:R-HSA-5687128
MAPK (ERK1/2) signaling KEGG:hsa_M00687
MAPK (ERK5) signaling KEGG:hsa_M00690
MAPK family signaling cascades REACT:R-HSA-5683057
MAP kinase activation in TLR cascade REACT:R-HSA-450294
MAPK (JNK) signaling KEGG:hsa_M00688
MAPK (p38) signaling KEGG:hsa_M00689
MAPK signaling pathway KEGG:hsa04010
MAPK targets/ Nuclear events mediated by MAP kinases REACT:R-HSA-450282
MASTL Facilitates Mitotic Progression REACT:R-HSA-2465910
Maturity onset diabetes of the young KEGG:hsa04950
MCM complex KEGG:hsa_M00285
Measles KEGG:hsa05162
Meiosis REACT:R-HSA-1500620
Meiotic recombination REACT:R-HSA-912446
Meiotic synapsis REACT:R-HSA-1221632
Melanin biosynthesis REACT:R-HSA-5662702
Melanogenesis KEGG:hsa04916
Melanoma KEGG:hsa05218
Melatonin biosynthesis, tryptophan => serotonin => melatonin KEGG:hsa_M00037
Membrane binding and targetting of GAG proteins REACT:R-HSA-174490
Membrane Trafficking REACT:R-HSA-199991
Metabolic disorders of biological oxidation enzymes REACT:R-HSA-5579029
Metabolic pathways KEGG:hsa01100
Metabolism REACT:R-HSA-1430728
Metabolism of amino acids and derivatives REACT:R-HSA-71291
Metabolism of Angiotensinogen to Angiotensins REACT:R-HSA-2022377
Metabolism of carbohydrates REACT:R-HSA-71387
Metabolism of fat-soluble vitamins REACT:R-HSA-6806667
Metabolism of folate and pterines REACT:R-HSA-196757
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se REACT:R-HSA-2408550
Metabolism of ingested MeSeO2H into MeSeH REACT:R-HSA-5263617
Metabolism of ingested SeMet, Sec, MeSec into H2Se REACT:R-HSA-2408508
Metabolism of lipids and lipoproteins REACT:R-HSA-556833
Metabolism of nitric oxide REACT:R-HSA-202131
Metabolism of non-coding RNA REACT:R-HSA-194441
Metabolism of nucleotides REACT:R-HSA-15869
Metabolism of polyamines REACT:R-HSA-351202
Metabolism of porphyrins REACT:R-HSA-189445
Metabolism of proteins REACT:R-HSA-392499
Metabolism of serotonin REACT:R-HSA-380612
Metabolism of steroid hormones REACT:R-HSA-196071
Metabolism of vitamin K REACT:R-HSA-6806664
Metabolism of vitamins and cofactors REACT:R-HSA-196854
Metabolism of water-soluble vitamins and cofactors REACT:R-HSA-196849
Metabolism of xenobiotics by cytochrome P450 KEGG:hsa00980
MET activates PI3K/AKT signaling REACT:R-HSA-8851907
MET activates PTK2 signaling REACT:R-HSA-8874081
MET activates PTPN11 REACT:R-HSA-8865999
MET activates RAP1 and RAC1 REACT:R-HSA-8875555
MET activates RAS signaling REACT:R-HSA-8851805
MET activates STAT3 REACT:R-HSA-8875791
Metal ion SLC transporters REACT:R-HSA-425410
Metalloprotease DUBs REACT:R-HSA-5689901
Metallothioneins bind metals REACT:R-HSA-5661231
Metal sequestration by antimicrobial proteins REACT:R-HSA-6799990
Methionine degradation KEGG:hsa_M00035
Methionine salvage pathway KEGG:hsa_M00034
Methionine salvage pathway REACT:R-HSA-1237112
Methylation REACT:R-HSA-156581
Methylation of MeSeH for excretion REACT:R-HSA-2408552
MET interacts with TNS proteins REACT:R-HSA-8875513
MET promotes cell motility REACT:R-HSA-8875878
MET Receptor Activation REACT:R-HSA-6806942
MET receptor recycling REACT:R-HSA-8875656
M/G1 Transition REACT:R-HSA-68874
MGMT-mediated DNA damage reversal REACT:R-HSA-5657655
MHC class II antigen presentation REACT:R-HSA-2132295
MicroRNA (miRNA) biogenesis REACT:R-HSA-203927
MicroRNAs in cancer KEGG:hsa05206
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane REACT:R-HSA-190840
Mineral absorption KEGG:hsa04978
Mineralocorticoid biosynthesis REACT:R-HSA-193993
Minus-strand DNA synthesis REACT:R-HSA-164516
Miscellaneous digestion events REACT:R-HSA-8935690
Miscellaneous substrates REACT:R-HSA-211958
Miscellaneous transport and binding events REACT:R-HSA-5223345
Mismatch repair KEGG:hsa03430
Mismatch Repair REACT:R-HSA-5358508
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) REACT:R-HSA-5358606
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) REACT:R-HSA-5358565
Misspliced GSK3beta mutants stabilize beta-catenin REACT:R-HSA-5339716
Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling REACT:R-HSA-5339717
Mitochondrial ABC transporters REACT:R-HSA-1369007
Mitochondrial biogenesis REACT:R-HSA-1592230
Mitochondrial Fatty Acid Beta-Oxidation REACT:R-HSA-77289
mitochondrial fatty acid beta-oxidation of saturated fatty acids REACT:R-HSA-77286
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids REACT:R-HSA-77288
Mitochondrial iron-sulfur cluster biogenesis REACT:R-HSA-1362409
Mitochondrial protein import REACT:R-HSA-1268020
Mitochondrial transcription initiation REACT:R-HSA-163282
Mitochondrial transcription termination REACT:R-HSA-163316
Mitochondrial translation REACT:R-HSA-5368287
Mitochondrial translation elongation REACT:R-HSA-5389840
Mitochondrial translation initiation REACT:R-HSA-5368286
Mitochondrial translation termination REACT:R-HSA-5419276
Mitochondrial tRNA aminoacylation REACT:R-HSA-379726
Mitochondrial Uncoupling Proteins REACT:R-HSA-166187
Mitophagy REACT:R-HSA-5205647
Mitophagy - animal KEGG:hsa04137
Mitotic Anaphase REACT:R-HSA-68882
Mitotic G1-G1/S phases REACT:R-HSA-453279
Mitotic G2-G2/M phases REACT:R-HSA-453274
Mitotic Metaphase/Anaphase Transition REACT:R-HSA-68881
Mitotic Metaphase and Anaphase REACT:R-HSA-2555396
Mitotic Prometaphase REACT:R-HSA-68877
Mitotic Prophase REACT:R-HSA-68875
Mitotic Spindle Checkpoint REACT:R-HSA-69618
Mitotic Telophase/Cytokinesis REACT:R-HSA-68884
Molecules associated with elastic fibres REACT:R-HSA-2129379
Molybdenum cofactor biosynthesis REACT:R-HSA-947581
Morphine addiction KEGG:hsa05032
M Phase REACT:R-HSA-68886
MPS I - Hurler syndrome REACT:R-HSA-2206302
MPS II - Hunter syndrome REACT:R-HSA-2206296
MPS IIIA - Sanfilippo syndrome A REACT:R-HSA-2206307
MPS IIIB - Sanfilippo syndrome B REACT:R-HSA-2206282
MPS IIIC - Sanfilippo syndrome C REACT:R-HSA-2206291
MPS IIID - Sanfilippo syndrome D REACT:R-HSA-2206305
MPS IV - Morquio syndrome A REACT:R-HSA-2206290
MPS IV - Morquio syndrome B REACT:R-HSA-2206308
MPS IX - Natowicz syndrome REACT:R-HSA-2206280
MPS VII - Sly syndrome REACT:R-HSA-2206292
MPS VI - Maroteaux-Lamy syndrome REACT:R-HSA-2206285
mRNA 3'-end processing REACT:R-HSA-72187
mRNA Capping REACT:R-HSA-72086
mRNA decay by 3' to 5' exoribonuclease REACT:R-HSA-429958
mRNA decay by 5' to 3' exoribonuclease REACT:R-HSA-430039
mRNA Editing REACT:R-HSA-75072
mRNA Editing: A to I Conversion REACT:R-HSA-75064
mRNA Editing: C to U Conversion REACT:R-HSA-72200
mRNA Splicing REACT:R-HSA-72172
mRNA Splicing - Major Pathway REACT:R-HSA-72163
mRNA Splicing - Minor Pathway REACT:R-HSA-72165
mRNA surveillance pathway KEGG:hsa03015
MRN complex KEGG:hsa_M00291
Mtb iron assimilation by chelation REACT:R-HSA-1222449
mTORC1-mediated signalling REACT:R-HSA-166208
mTOR signaling pathway KEGG:hsa04150
mTOR signalling REACT:R-HSA-165159
Mucin type O-glycan biosynthesis KEGG:hsa00512
Mucopolysaccharidoses REACT:R-HSA-2206281
Multifunctional anion exchangers REACT:R-HSA-427601
Muscarinic acetylcholine receptors REACT:R-HSA-390648
Muscle contraction REACT:R-HSA-397014
MyD88 cascade initiated on plasma membrane REACT:R-HSA-975871
MyD88 deficiency (TLR2/4) REACT:R-HSA-5602498
MyD88 deficiency (TLR5) REACT:R-HSA-5602680
MyD88 dependent cascade initiated on endosome REACT:R-HSA-975155
MyD88-independent TLR3/TLR4 cascade REACT:R-HSA-166166
MyD88:Mal cascade initiated on plasma membrane REACT:R-HSA-166058
Myoclonic epilepsy of Lafora REACT:R-HSA-3785653
Myogenesis REACT:R-HSA-525793
Na+/Cl- dependent neurotransmitter transporters REACT:R-HSA-442660
NADE modulates death signalling REACT:R-HSA-205025
Na+-dependent glucose transporters REACT:R-HSA-428808
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex KEGG:hsa_M00146
NADH dehydrogenase (ubiquinone) 1 beta subcomplex KEGG:hsa_M00147
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria KEGG:hsa_M00143
NADH:ubiquinone oxidoreductase, mitochondria KEGG:hsa_M00142
NADPH regeneration REACT:R-HSA-389542
Natural killer cell mediated cytotoxicity KEGG:hsa04650
NCAM1 interactions REACT:R-HSA-419037
NCAM signaling for neurite out-growth REACT:R-HSA-375165
Nectin/Necl trans heterodimerization REACT:R-HSA-420597
Nef and signal transduction REACT:R-HSA-164944
Nef Mediated CD4 Down-regulation REACT:R-HSA-167590
Nef Mediated CD8 Down-regulation REACT:R-HSA-182218
Nef mediated downregulation of CD28 cell surface expression REACT:R-HSA-164939
Nef mediated downregulation of MHC class I complex cell surface expression REACT:R-HSA-164940
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters REACT:R-HSA-164938
Negative epigenetic regulation of rRNA expression REACT:R-HSA-5250941
Negative feedback regulation of MAPK pathway REACT:R-HSA-5674499
Negative regulation of activity of TFAP2 (AP-2) family transcription factors REACT:R-HSA-8866904
Negative regulation of FGFR1 signaling REACT:R-HSA-5654726
Negative regulation of FGFR2 signaling REACT:R-HSA-5654727
Negative regulation of FGFR3 signaling REACT:R-HSA-5654732
Negative regulation of FGFR4 signaling REACT:R-HSA-5654733
Negative regulation of MAPK pathway REACT:R-HSA-5675221
Negative regulation of MET activity REACT:R-HSA-6807004
Negative regulation of TCF-dependent signaling by DVL-interacting proteins REACT:R-HSA-5368598
Negative regulation of TCF-dependent signaling by WNT ligand antagonists REACT:R-HSA-3772470
Negative regulation of the PI3K/AKT network REACT:R-HSA-199418
Negative regulators of RIG-I/MDA5 signaling REACT:R-HSA-936440
Neomycin, kanamycin and gentamicin biosynthesis KEGG:hsa00524
Nephrin interactions REACT:R-HSA-373753
NEP/NS2 Interacts with the Cellular Export Machinery REACT:R-HSA-168333
Netrin-1 signaling REACT:R-HSA-373752
Netrin mediated repulsion signals REACT:R-HSA-418886
Neuroactive ligand-receptor interaction KEGG:hsa04080
Neurodegenerative Diseases REACT:R-HSA-8863678
Neurofascin interactions REACT:R-HSA-447043
Neuronal System REACT:R-HSA-112316
Neurophilin interactions with VEGF and VEGFR REACT:R-HSA-194306
Neurotoxicity of clostridium toxins REACT:R-HSA-168799
Neurotransmitter Clearance In The Synaptic Cleft REACT:R-HSA-112311
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell REACT:R-HSA-112314
Neurotransmitter Release Cycle REACT:R-HSA-112310
Neurotransmitter uptake and Metabolism In Glial Cells REACT:R-HSA-112313
Neurotrophin signaling pathway KEGG:hsa04722
Neutrophil degranulation REACT:R-HSA-6798695
NFG and proNGF binds to p75NTR REACT:R-HSA-205017
NF-kappa B signaling pathway KEGG:hsa04064
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 REACT:R-HSA-933543
NF-kB is activated and signals survival REACT:R-HSA-209560
NGF-independant TRKA activation REACT:R-HSA-187024
NGF processing REACT:R-HSA-167060
NGF signalling via TRKA from the plasma membrane REACT:R-HSA-187037
N-Glycan antennae elongation REACT:R-HSA-975577
N-glycan antennae elongation in the medial/trans-Golgi REACT:R-HSA-975576
N-Glycan biosynthesis KEGG:hsa00510
N-glycan biosynthesis, complex type KEGG:hsa_M00075
N-glycan precursor biosynthesis KEGG:hsa_M00055
N-glycan precursor trimming KEGG:hsa_M00073
N-glycan trimming and elongation in the cis-Golgi REACT:R-HSA-964739
N-glycan trimming in the ER and Calnexin/Calreticulin cycle REACT:R-HSA-532668
N-glycosylation by oligosaccharyltransferase KEGG:hsa_M00072
Nicotinamide salvaging REACT:R-HSA-197264
Nicotinate and nicotinamide metabolism KEGG:hsa00760
Nicotinate metabolism REACT:R-HSA-196807
Nicotine addiction KEGG:hsa05033
NIK-->noncanonical NF-kB signaling REACT:R-HSA-5676590
Nitric oxide stimulates guanylate cyclase REACT:R-HSA-392154
Nitrogen metabolism KEGG:hsa00910
NOD1/2 Signaling Pathway REACT:R-HSA-168638
NOD-like receptor signaling pathway KEGG:hsa04621
Non-alcoholic fatty liver disease (NAFLD) KEGG:hsa04932
Non-homologous end-joining KEGG:hsa03450
Nonhomologous End-Joining (NHEJ) REACT:R-HSA-5693571
Non-integrin membrane-ECM interactions REACT:R-HSA-3000171
Nonsense-Mediated Decay (NMD) REACT:R-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) REACT:R-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) REACT:R-HSA-975956
Non-small cell lung cancer KEGG:hsa05223
NoRC negatively regulates rRNA expression REACT:R-HSA-427413
Norepinephrine Neurotransmitter Release Cycle REACT:R-HSA-181430
NOSIP mediated eNOS trafficking REACT:R-HSA-203754
NOSTRIN mediated eNOS trafficking REACT:R-HSA-203641
NOTCH1 Intracellular Domain Regulates Transcription REACT:R-HSA-2122947
NOTCH2 Activation and Transmission of Signal to the Nucleus REACT:R-HSA-2979096
NOTCH2 intracellular domain regulates transcription REACT:R-HSA-2197563
Notch-HLH transcription pathway REACT:R-HSA-350054
Notch signaling KEGG:hsa_M00682
Notch signaling pathway KEGG:hsa04330
NR1D1 (REV-ERBA) represses gene expression REACT:R-HSA-1368071
NRAGE signals death through JNK REACT:R-HSA-193648
NrCAM interactions REACT:R-HSA-447038
NRIF signals cell death from the nucleus REACT:R-HSA-205043
NS1 Mediated Effects on Host Pathways REACT:R-HSA-168276
Nuclear Envelope Breakdown REACT:R-HSA-2980766
Nuclear Envelope Reassembly REACT:R-HSA-2995410
Nuclear Events (kinase and transcription factor activation) REACT:R-HSA-198725
Nuclear import of Rev protein REACT:R-HSA-180746
Nuclear pore complex KEGG:hsa_M00427
Nuclear Pore Complex (NPC) Disassembly REACT:R-HSA-3301854
Nuclear Receptor transcription pathway REACT:R-HSA-383280
Nuclear signaling by ERBB4 REACT:R-HSA-1251985
Nucleosome assembly REACT:R-HSA-774815
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways REACT:R-HSA-168643
Nucleotide excision repair KEGG:hsa03420
Nucleotide Excision Repair REACT:R-HSA-5696398
Nucleotide-like (purinergic) receptors REACT:R-HSA-418038
Nucleotide sugar biosynthesis, eukaryotes KEGG:hsa_M00361
Nucleotide sugar biosynthesis, galactose => UDP-galactose KEGG:hsa_M00554
Nucleotide sugar biosynthesis, glucose => UDP-glucose KEGG:hsa_M00549
O2/CO2 exchange in erythrocytes REACT:R-HSA-1480926
O-glycan biosynthesis, mucin type core KEGG:hsa_M00056
O-glycosylation of TSR domain-containing proteins REACT:R-HSA-5173214
Olfactory Signaling Pathway REACT:R-HSA-381753
Olfactory transduction KEGG:hsa04740
Oligomerization of connexins into connexons REACT:R-HSA-190704
O-linked glycosylation REACT:R-HSA-5173105
O-linked glycosylation of mucins REACT:R-HSA-913709
Oncogene Induced Senescence REACT:R-HSA-2559585
Oncogenic MAPK signaling REACT:R-HSA-6802957
One carbon pool by folate KEGG:hsa00670
Oocyte meiosis KEGG:hsa04114
Opioid Signalling REACT:R-HSA-111885
Opsins REACT:R-HSA-419771
Orc1 removal from chromatin REACT:R-HSA-68949
Orexin and neuropeptides FF and QRFP bind to their respective receptors REACT:R-HSA-389397
Organelle biogenesis and maintenance REACT:R-HSA-1852241
Organic anion transport REACT:R-HSA-561048
Organic anion transporters REACT:R-HSA-428643
Organic cation/anion/zwitterion transport REACT:R-HSA-549132
Organic cation transport REACT:R-HSA-549127
Origin recognition complex KEGG:hsa_M00284
Osteoclast differentiation KEGG:hsa04380
Other glycan degradation KEGG:hsa00511
Other semaphorin interactions REACT:R-HSA-416700
Other types of O-glycan biosynthesis KEGG:hsa00514
Ovarian steroidogenesis KEGG:hsa04913
Ovarian tumor domain proteases REACT:R-HSA-5689896
Oxidative phosphorylation KEGG:hsa00190
Oxidative Stress Induced Senescence REACT:R-HSA-2559580
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234162
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234176
Oxytocin signaling pathway KEGG:hsa04921
p130Cas linkage to MAPK signaling for integrins REACT:R-HSA-372708
P2Y receptors REACT:R-HSA-417957
p38MAPK events REACT:R-HSA-171007
p53-Dependent G1 DNA Damage Response REACT:R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint REACT:R-HSA-69580
p53-Independent DNA Damage Response REACT:R-HSA-69610
p53-Independent G1/S DNA damage checkpoint REACT:R-HSA-69613
p53 signaling pathway KEGG:hsa04115
p75NTR negatively regulates cell cycle via SC1 REACT:R-HSA-193670
p75 NTR receptor-mediated signalling REACT:R-HSA-193704
p75NTR recruits signalling complexes REACT:R-HSA-209543
p75NTR regulates axonogenesis REACT:R-HSA-193697
p75NTR signals via NF-kB REACT:R-HSA-193639
p97-Ufd1-Npl4 complex KEGG:hsa_M00400
Packaging of Eight RNA Segments REACT:R-HSA-168303
Packaging Of Telomere Ends REACT:R-HSA-171306
Pancreatic cancer KEGG:hsa05212
Pancreatic secretion KEGG:hsa04972
Pantothenate and CoA biosynthesis KEGG:hsa00770
PAOs oxidise polyamines to amines REACT:R-HSA-141334
Paradoxical activation of RAF signaling by kinase inactive BRAF REACT:R-HSA-6802955
Parkinson's disease KEGG:hsa05012
Passive transport by Aquaporins REACT:R-HSA-432047
Pathogenic Escherichia coli infection KEGG:hsa05130
Pathways in cancer KEGG:hsa05200
Pausing and recovery of HIV elongation REACT:R-HSA-167290
Pausing and recovery of Tat-mediated HIV elongation REACT:R-HSA-167238
PCNA-Dependent Long Patch Base Excision Repair REACT:R-HSA-5651801
PCP/CE pathway REACT:R-HSA-4086400
PD-1 signaling REACT:R-HSA-389948
PDE3B signalling REACT:R-HSA-165160
PECAM1 interactions REACT:R-HSA-210990
Pentose and glucuronate interconversions KEGG:hsa00040
Pentose phosphate pathway KEGG:hsa00030
Pentose phosphate pathway disease REACT:R-HSA-6791465
Pentose phosphate pathway (hexose monophosphate shunt) REACT:R-HSA-71336
Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P KEGG:hsa_M00007
Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P KEGG:hsa_M00006
Pentose phosphate pathway (Pentose phosphate cycle) KEGG:hsa_M00004
Peptide chain elongation REACT:R-HSA-156902
Peptide hormone biosynthesis REACT:R-HSA-209952
Peptide hormone metabolism REACT:R-HSA-2980736
Peptide ligand-binding receptors REACT:R-HSA-375276
PERK regulates gene expression REACT:R-HSA-381042
Peroxisomal lipid metabolism REACT:R-HSA-390918
Peroxisome KEGG:hsa04146
Pertussis KEGG:hsa05133
Phagosome KEGG:hsa04145
Phase 0 - rapid depolarisation REACT:R-HSA-5576892
Phase 1 - Functionalization of compounds REACT:R-HSA-211945
Phase 1 - inactivation of fast Na+ channels REACT:R-HSA-5576894
Phase 2 - plateau phase REACT:R-HSA-5576893
Phase 3 - rapid repolarisation REACT:R-HSA-5576890
Phase 4 - resting membrane potential REACT:R-HSA-5576886
Phase II conjugation REACT:R-HSA-156580
Phenylalanine and tyrosine catabolism REACT:R-HSA-71182
Phenylalanine metabolism KEGG:hsa00360
Phenylalanine, tyrosine and tryptophan biosynthesis KEGG:hsa00400
Phenylketonuria REACT:R-HSA-2160456
Phosphate bond hydrolysis by NTPDase proteins REACT:R-HSA-8850843
Phosphate bond hydrolysis by NUDT proteins REACT:R-HSA-2393930
Phosphatidylcholine (PC) biosynthesis, choline => PC KEGG:hsa_M00090
Phosphatidylcholine (PC) biosynthesis, PE => PC KEGG:hsa_M00091
Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE KEGG:hsa_M00092
Phosphatidylinositol signaling system KEGG:hsa04070
Phospholipase C-mediated cascade: FGFR1 REACT:R-HSA-5654219
Phospholipase C-mediated cascade; FGFR2 REACT:R-HSA-5654221
Phospholipase C-mediated cascade; FGFR3 REACT:R-HSA-5654227
Phospholipase C-mediated cascade; FGFR4 REACT:R-HSA-5654228
Phospholipase D signaling pathway KEGG:hsa04072
Phospholipid metabolism REACT:R-HSA-1483257
Phosphonate and phosphinate metabolism KEGG:hsa00440
phospho-PLA2 pathway REACT:R-HSA-111995
Phosphorylation of CD3 and TCR zeta chains REACT:R-HSA-202427
Phosphorylation of Emi1 REACT:R-HSA-176417
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes REACT:R-HSA-69200
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes REACT:R-HSA-170145
Phosphorylation of the APC/C REACT:R-HSA-176412
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex REACT:R-HSA-4839743
Phototransduction KEGG:hsa04744
Physiological factors REACT:R-HSA-5578768
PI3K/AKT activation REACT:R-HSA-198203
PI3K-Akt signaling KEGG:hsa_M00676
PI3K/AKT Signaling in Cancer REACT:R-HSA-2219528
PI3K-Akt signaling pathway KEGG:hsa04151
PI3K Cascade REACT:R-HSA-109704
PI-3K cascade:FGFR1 REACT:R-HSA-5654689
PI-3K cascade:FGFR2 REACT:R-HSA-5654695
PI-3K cascade:FGFR3 REACT:R-HSA-5654710
PI-3K cascade:FGFR4 REACT:R-HSA-5654720
PI3K events in ERBB2 signaling REACT:R-HSA-1963642
PI3K events in ERBB4 signaling REACT:R-HSA-1250342
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling REACT:R-HSA-6811558
PI5P Regulates TP53 Acetylation REACT:R-HSA-6811555
PI and PC transport between ER and Golgi membranes REACT:R-HSA-1483196
PI Metabolism REACT:R-HSA-1483255
Pink/Parkin Mediated Mitophagy REACT:R-HSA-5205685
PIP3 activates AKT signaling REACT:R-HSA-1257604
PIPs transport between early and late endosome membranes REACT:R-HSA-1660502
PIPs transport between early endosome and Golgi membranes REACT:R-HSA-1660537
PIPs transport between Golgi and plasma membranes REACT:R-HSA-1660510
PIPs transport between late endosome and Golgi membranes REACT:R-HSA-1660508
PIPs transport between plasma and early endosome membranes REACT:R-HSA-1660524
PIWI-interacting RNA (piRNA) biogenesis REACT:R-HSA-5601884
PKA activation REACT:R-HSA-163615
PKA activation in glucagon signalling REACT:R-HSA-164378
PKA-mediated phosphorylation of CREB REACT:R-HSA-111931
PKA-mediated phosphorylation of key metabolic factors REACT:R-HSA-163358
PKB-mediated events REACT:R-HSA-109703
PKMTs methylate histone lysines REACT:R-HSA-3214841
Plasmalogen biosynthesis REACT:R-HSA-75896
Platelet activation KEGG:hsa04611
Platelet activation, signaling and aggregation REACT:R-HSA-76002
Platelet Adhesion to exposed collagen REACT:R-HSA-75892
Platelet Aggregation (Plug Formation) REACT:R-HSA-76009
Platelet calcium homeostasis REACT:R-HSA-418360
Platelet degranulation REACT:R-HSA-114608
Platelet homeostasis REACT:R-HSA-418346
Platelet sensitization by LDL REACT:R-HSA-432142
Platinum drug resistance KEGG:hsa01524
PLC beta mediated events REACT:R-HSA-112043
PLCG1 events in ERBB2 signaling REACT:R-HSA-1251932
PLC-gamma1 signalling REACT:R-HSA-167021
Plus-strand DNA synthesis REACT:R-HSA-164525
POLB-Dependent Long Patch Base Excision Repair REACT:R-HSA-110362
Polo-like kinase mediated events REACT:R-HSA-156711
Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine KEGG:hsa_M00133
Polyamine biosynthesis, arginine => ornithine => putrescine KEGG:hsa_M00134
Polymerase switching REACT:R-HSA-69091
Polymerase switching on the C-strand of the telomere REACT:R-HSA-174411
Porphyrin and chlorophyll metabolism KEGG:hsa00860
Positive epigenetic regulation of rRNA expression REACT:R-HSA-5250913
Post-chaperonin tubulin folding pathway REACT:R-HSA-389977
Post NMDA receptor activation events REACT:R-HSA-438064
Postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-622327
Post-transcriptional silencing by small RNAs REACT:R-HSA-426496
Post-translational modification: synthesis of GPI-anchored proteins REACT:R-HSA-163125
Post-translational protein modification REACT:R-HSA-597592
Potassium Channels REACT:R-HSA-1296071
Potassium transport channels REACT:R-HSA-1296067
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation REACT:R-HSA-2892247
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation REACT:R-HSA-2892245
PP2A-mediated dephosphorylation of key metabolic factors REACT:R-HSA-163767
PPARA activates gene expression REACT:R-HSA-1989781
PPAR signaling pathway KEGG:hsa03320
PRC2 methylates histones and DNA REACT:R-HSA-212300
Prefoldin mediated transfer of substrate to CCT/TriC REACT:R-HSA-389957
Pregnenolone biosynthesis REACT:R-HSA-196108
Pre-NOTCH Expression and Processing REACT:R-HSA-1912422
Pre-NOTCH Processing in Golgi REACT:R-HSA-1912420
Pre-NOTCH Processing in the Endoplasmic Reticulum REACT:R-HSA-1912399
Pre-NOTCH Transcription and Translation REACT:R-HSA-1912408
Presynaptic function of Kainate receptors REACT:R-HSA-500657
Presynaptic nicotinic acetylcholine receptors REACT:R-HSA-622323
Presynaptic phase of homologous DNA pairing and strand exchange REACT:R-HSA-5693616
Primary bile acid biosynthesis KEGG:hsa00120
Primary immunodeficiency KEGG:hsa05340
Prion diseases KEGG:hsa05020
Processing and activation of SUMO REACT:R-HSA-3215018
Processing of Capped Intron-Containing Pre-mRNA REACT:R-HSA-72203
Processing of Capped Intronless Pre-mRNA REACT:R-HSA-75067
Processing of DNA double-strand break ends REACT:R-HSA-5693607
Processing of Intronless Pre-mRNAs REACT:R-HSA-77595
Processive synthesis on the C-strand of the telomere REACT:R-HSA-174414
Processive synthesis on the lagging strand REACT:R-HSA-69183
Progesterone-mediated oocyte maturation KEGG:hsa04914
Programmed Cell Death REACT:R-HSA-5357801
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 REACT:R-HSA-964827
Prolactin receptor signaling REACT:R-HSA-1170546
Prolactin signaling pathway KEGG:hsa04917
Proline biosynthesis, glutamate => proline KEGG:hsa_M00015
Proline catabolism REACT:R-HSA-70688
Prolonged ERK activation events REACT:R-HSA-169893
Propanoate metabolism KEGG:hsa00640
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA KEGG:hsa_M00741
Propionyl-CoA catabolism REACT:R-HSA-71032
Prostacyclin signalling through prostacyclin receptor REACT:R-HSA-392851
Prostanoid ligand receptors REACT:R-HSA-391908
Prostate cancer KEGG:hsa05215
Proteasome KEGG:hsa03050
Proteasome, 19S regulatory particle (PA700) KEGG:hsa_M00341
Proteasome, 20S core particle KEGG:hsa_M00340
Protein digestion and absorption KEGG:hsa04974
Protein export KEGG:hsa03060
Protein folding REACT:R-HSA-391251
Protein methylation REACT:R-HSA-8876725
Protein processing in endoplasmic reticulum KEGG:hsa04141
Protein-protein interactions at synapses REACT:R-HSA-6794362
Protein repair REACT:R-HSA-5676934
Protein ubiquitination REACT:R-HSA-8852135
Proteoglycans in cancer KEGG:hsa05205
Proton-coupled monocarboxylate transport REACT:R-HSA-433692
Proton-coupled neutral amino acid transporters REACT:R-HSA-428559
Proton/oligopeptide cotransporters REACT:R-HSA-427975
Proximal tubule bicarbonate reclamation KEGG:hsa04964
PRPP biosynthesis, ribose 5P => PRPP KEGG:hsa_M00005
PTEN Loss of Function in Cancer REACT:R-HSA-5674404
PTK6 Activates STAT3 REACT:R-HSA-8849474
PTK6 Down-Regulation REACT:R-HSA-8849472
PTK6 Expression REACT:R-HSA-8849473
PTK6 promotes HIF1A stabilization REACT:R-HSA-8857538
PTK6 Regulates Cell Cycle REACT:R-HSA-8849470
PTK6 Regulates Proteins Involved in RNA Processing REACT:R-HSA-8849468
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases REACT:R-HSA-8849471
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 REACT:R-HSA-8849469
Purine catabolism REACT:R-HSA-74259
Purine metabolism KEGG:hsa00230
Purine metabolism REACT:R-HSA-73847
Purine ribonucleoside monophosphate biosynthesis REACT:R-HSA-73817
Purine salvage REACT:R-HSA-74217
Pyrimidine biosynthesis REACT:R-HSA-500753
Pyrimidine catabolism REACT:R-HSA-73621
Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate KEGG:hsa_M00046
Pyrimidine metabolism KEGG:hsa00240
Pyrimidine metabolism REACT:R-HSA-73848
Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP KEGG:hsa_M00052
Pyrimidine salvage reactions REACT:R-HSA-73614
Pyrophosphate hydrolysis REACT:R-HSA-71737
Pyruvate metabolism KEGG:hsa00620
Pyruvate metabolism REACT:R-HSA-70268
Pyruvate metabolism and Citric Acid (TCA) cycle REACT:R-HSA-71406
Pyruvate oxidation, pyruvate => acetyl-CoA KEGG:hsa_M00307
RAB GEFs exchange GTP for GDP on RABs REACT:R-HSA-8876198
RAB geranylgeranylation REACT:R-HSA-8873719
RA biosynthesis pathway REACT:R-HSA-5365859
RAF activation REACT:R-HSA-5673000
RAF-independent MAPK1/3 activation REACT:R-HSA-112409
RAF/MAP kinase cascade REACT:R-HSA-5673001
Rap1 signaling pathway KEGG:hsa04015
Rap1 signalling REACT:R-HSA-392517
Ras activation uopn Ca2+ infux through NMDA receptor REACT:R-HSA-442982
RAS signaling downstream of NF1 loss-of-function variants REACT:R-HSA-6802953
Ras signaling pathway KEGG:hsa04014
Reactions specific to the complex N-glycan synthesis pathway REACT:R-HSA-975578
Reactions specific to the hybrid N-glycan synthesis pathway REACT:R-HSA-975574
Recognition and association of DNA glycosylase with site containing an affected purine REACT:R-HSA-110330
Recognition and association of DNA glycosylase with site containing an affected pyrimidine REACT:R-HSA-110328
Recognition of DNA damage by PCNA-containing replication complex REACT:R-HSA-110314
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks REACT:R-HSA-5693565
Recruitment of mitotic centrosome proteins and complexes REACT:R-HSA-380270
Recruitment of NuMA to mitotic centrosomes REACT:R-HSA-380320
Recycling of bile acids and salts REACT:R-HSA-159418
Recycling of eIF2:GDP REACT:R-HSA-72731
Recycling pathway of L1 REACT:R-HSA-437239
Reduction of cytosolic Ca++ levels REACT:R-HSA-418359
Reelin signalling pathway REACT:R-HSA-8866376
Regulated Necrosis REACT:R-HSA-5218859
Regulated proteolysis of p75NTR REACT:R-HSA-193692
Regulation by c-FLIP REACT:R-HSA-3371378
Regulation by TREX1 REACT:R-HSA-3248023
Regulation of actin cytoskeleton KEGG:hsa04810
Regulation of actin dynamics for phagocytic cup formation REACT:R-HSA-2029482
Regulation of activated PAK-2p34 by proteasome mediated degradation REACT:R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase REACT:R-HSA-176408
Regulation of Apoptosis REACT:R-HSA-169911
Regulation of beta-cell development REACT:R-HSA-186712
Regulation of cholesterol biosynthesis by SREBP (SREBF) REACT:R-HSA-1655829
Regulation of Commissural axon pathfinding by Slit and Robo REACT:R-HSA-428542
Regulation of Complement cascade REACT:R-HSA-977606
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components REACT:R-HSA-446388
Regulation of DNA replication REACT:R-HSA-69304
Regulation of FZD by ubiquitination REACT:R-HSA-4641263
Regulation of gap junction activity REACT:R-HSA-191650
Regulation of gene expression by Hypoxia-inducible Factor REACT:R-HSA-1234158
Regulation of gene expression in beta cells REACT:R-HSA-210745
Regulation of gene expression in early pancreatic precursor cells REACT:R-HSA-210747
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells REACT:R-HSA-210746
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells REACT:R-HSA-210744
Regulation of Glucokinase by Glucokinase Regulatory Protein REACT:R-HSA-170822
Regulation of HSF1-mediated heat shock response REACT:R-HSA-3371453
Regulation of Hypoxia-inducible Factor (HIF) by oxygen REACT:R-HSA-1234174
Regulation of IFNA signaling REACT:R-HSA-912694
Regulation of IFNG signaling REACT:R-HSA-877312
Regulation of innate immune responses to cytosolic DNA REACT:R-HSA-3134975
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) REACT:R-HSA-381426
Regulation of insulin secretion REACT:R-HSA-422356
Regulation of KIT signaling REACT:R-HSA-1433559
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) REACT:R-HSA-400206
Regulation of lipolysis in adipocytes KEGG:hsa04923
Regulation of mitotic cell cycle REACT:R-HSA-453276
Regulation of mRNA stability by proteins that bind AU-rich elements REACT:R-HSA-450531
Regulation of necroptotic cell death REACT:R-HSA-5675482
Regulation of ornithine decarboxylase (ODC) REACT:R-HSA-350562
Regulation of PAK-2p34 activity by PS-GAP/RHG10 REACT:R-HSA-211728
Regulation of PLK1 Activity at G2/M Transition REACT:R-HSA-2565942
Regulation of pyruvate dehydrogenase (PDH) complex REACT:R-HSA-204174
Regulation of RAS by GAPs REACT:R-HSA-5658442
Regulation of signaling by CBL REACT:R-HSA-912631
Regulation of signaling by NODAL REACT:R-HSA-1433617
Regulation of thyroid hormone activity REACT:R-HSA-350864
Regulation of TLR by endogenous ligand REACT:R-HSA-5686938
Regulation of TNFR1 signaling REACT:R-HSA-5357905
Regulation of TP53 Activity REACT:R-HSA-5633007
Regulation of TP53 Activity through Acetylation REACT:R-HSA-6804758
Regulation of TP53 Activity through Association with Co-factors REACT:R-HSA-6804759
Regulation of TP53 Activity through Methylation REACT:R-HSA-6804760
Regulation of TP53 Activity through Phosphorylation REACT:R-HSA-6804756
Regulation of TP53 Degradation REACT:R-HSA-6804757
Regulation of TP53 Expression REACT:R-HSA-6804754
Regulation of TP53 Expression and Degradation REACT:R-HSA-6806003
Relaxin receptors REACT:R-HSA-444821
Release REACT:R-HSA-168298
Release of apoptotic factors from the mitochondria REACT:R-HSA-111457
Release of Hh-Np from the secreting cell REACT:R-HSA-5362798
Removal of aminoterminal propeptides from gamma-carboxylated proteins REACT:R-HSA-159782
Removal of licensing factors from origins REACT:R-HSA-69300
Removal of the Flap Intermediate REACT:R-HSA-69166
Removal of the Flap Intermediate from the C-strand REACT:R-HSA-174437
Renal cell carcinoma KEGG:hsa05211
Renin-angiotensin system KEGG:hsa04614
Renin secretion KEGG:hsa04924
Repression of WNT target genes REACT:R-HSA-4641265
Reproduction REACT:R-HSA-1474165
Resolution of Abasic Sites (AP sites) REACT:R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway REACT:R-HSA-110373
Resolution of AP sites via the single-nucleotide replacement pathway REACT:R-HSA-110381
Resolution of D-Loop Structures REACT:R-HSA-5693537
Resolution of D-loop Structures through Holliday Junction Intermediates REACT:R-HSA-5693568
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) REACT:R-HSA-5693554
Resolution of Sister Chromatid Cohesion REACT:R-HSA-2500257
Respiratory electron transport REACT:R-HSA-611105
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. REACT:R-HSA-163200
Response of Mtb to phagocytosis REACT:R-HSA-1222499
Response to elevated platelet cytosolic Ca2+ REACT:R-HSA-76005
Response to metal ions REACT:R-HSA-5660526
Retinoid cycle disease events REACT:R-HSA-2453864
Retinoid metabolism and transport REACT:R-HSA-975634
Retinoid metabolism disease events REACT:R-HSA-6809583
Retinol metabolism KEGG:hsa00830
Retrograde endocannabinoid signaling KEGG:hsa04723
Retrograde neurotrophin signalling REACT:R-HSA-177504
Retrograde transport at the Trans-Golgi-Network REACT:R-HSA-6811440
RET signaling REACT:R-HSA-8853659
Reuptake of GABA REACT:R-HSA-888593
Reversal of alkylation damage by DNA dioxygenases REACT:R-HSA-73943
Reverse Transcription of HIV RNA REACT:R-HSA-162589
Reversible hydration of carbon dioxide REACT:R-HSA-1475029
Rev-mediated nuclear export of HIV RNA REACT:R-HSA-165054
RF-C complex KEGG:hsa_M00289
Rhesus glycoproteins mediate ammonium transport. REACT:R-HSA-444411
Rheumatoid arthritis KEGG:hsa05323
Rho GTPase cycle REACT:R-HSA-194840
RHO GTPase Effectors REACT:R-HSA-195258
RHO GTPases activate CIT REACT:R-HSA-5625900
RHO GTPases Activate Formins REACT:R-HSA-5663220
RHO GTPases activate IQGAPs REACT:R-HSA-5626467
RHO GTPases activate KTN1 REACT:R-HSA-5625970
RHO GTPases Activate NADPH Oxidases REACT:R-HSA-5668599
RHO GTPases activate PAKs REACT:R-HSA-5627123
RHO GTPases activate PKNs REACT:R-HSA-5625740
RHO GTPases Activate Rhotekin and Rhophilins REACT:R-HSA-5666185
RHO GTPases Activate ROCKs REACT:R-HSA-5627117
RHO GTPases Activate WASPs and WAVEs REACT:R-HSA-5663213
RHO GTPases regulate CFTR trafficking REACT:R-HSA-5627083
Riboflavin metabolism KEGG:hsa00740
Ribosomal scanning and start codon recognition REACT:R-HSA-72702
Ribosome KEGG:hsa03010
Ribosome biogenesis in eukaryotes KEGG:hsa03008
Ribosome, eukaryotes KEGG:hsa_M00177
RIG-I-like receptor signaling pathway KEGG:hsa04622
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways REACT:R-HSA-168928
RIPK1-mediated regulated necrosis REACT:R-HSA-5213460
RIP-mediated NFkB activation via ZBP1 REACT:R-HSA-1810476
RMTs methylate histone arginines REACT:R-HSA-3214858
RNA degradation KEGG:hsa03018
RNA Pol II CTD phosphorylation and interaction with CE REACT:R-HSA-77075
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection REACT:R-HSA-167160
RNA polymerase KEGG:hsa03020
RNA Polymerase I Chain Elongation REACT:R-HSA-73777
RNA polymerase I, eukaryotes KEGG:hsa_M00182
RNA polymerase II, eukaryotes KEGG:hsa_M00180
RNA Polymerase II HIV Promoter Escape REACT:R-HSA-167162
RNA Polymerase III Abortive And Retractive Initiation REACT:R-HSA-749476
RNA Polymerase III Chain Elongation REACT:R-HSA-73780
RNA polymerase III, eukaryotes KEGG:hsa_M00181
RNA Polymerase III Transcription REACT:R-HSA-74158
RNA Polymerase III Transcription Initiation REACT:R-HSA-76046
RNA Polymerase III Transcription Initiation From Type 1 Promoter REACT:R-HSA-76061
RNA Polymerase III Transcription Initiation From Type 2 Promoter REACT:R-HSA-76066
RNA Polymerase III Transcription Initiation From Type 3 Promoter REACT:R-HSA-76071
RNA Polymerase III Transcription Termination REACT:R-HSA-73980
RNA Polymerase II Pre-transcription Events REACT:R-HSA-674695
RNA Polymerase II Promoter Escape REACT:R-HSA-73776
RNA polymerase II transcribes snRNA genes REACT:R-HSA-6807505
RNA Polymerase II Transcription REACT:R-HSA-73857
RNA Polymerase II Transcription Elongation REACT:R-HSA-75955
RNA Polymerase II Transcription Initiation REACT:R-HSA-75953
RNA Polymerase II Transcription Initiation And Promoter Clearance REACT:R-HSA-76042
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening REACT:R-HSA-73779
RNA Polymerase II Transcription Termination REACT:R-HSA-73856
RNA Polymerase I Promoter Clearance REACT:R-HSA-73854
RNA Polymerase I Promoter Escape REACT:R-HSA-73772
RNA Polymerase I Promoter Opening REACT:R-HSA-73728
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription REACT:R-HSA-504046
RNA Polymerase I Transcription REACT:R-HSA-73864
RNA Polymerase I Transcription Initiation REACT:R-HSA-73762
RNA Polymerase I Transcription Termination REACT:R-HSA-73863
RNA transport KEGG:hsa03013
RNF mutants show enhanced WNT signaling and proliferation REACT:R-HSA-5340588
Role of Abl in Robo-Slit signaling REACT:R-HSA-428890
Role of LAT2/NTAL/LAB on calcium mobilization REACT:R-HSA-2730905
Role of phospholipids in phagocytosis REACT:R-HSA-2029485
Role of second messengers in netrin-1 signaling REACT:R-HSA-418890
RORA activates gene expression REACT:R-HSA-1368082
ROS, RNS production in phagocytes REACT:R-HSA-1222556
RPA complex KEGG:hsa_M00288
RPIA deficiency: failed conversion of R5P to RU5P REACT:R-HSA-5659996
RPIA deficiency: failed conversion of RU5P to R5P REACT:R-HSA-6791461
rRNA modification in the mitochondrion REACT:R-HSA-6793080
rRNA modification in the nucleus and cytosol REACT:R-HSA-6790901
rRNA processing REACT:R-HSA-72312
rRNA processing in the mitochondrion REACT:R-HSA-8868766
rRNA processing in the nucleus and cytosol REACT:R-HSA-8868773
RSK activation REACT:R-HSA-444257
S33 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358747
S37 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358749
S45 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358751
Salivary secretion KEGG:hsa04970
Salmonella infection KEGG:hsa05132
SALM protein interactions at the synapses REACT:R-HSA-8849932
Scavenging by Class A Receptors REACT:R-HSA-3000480
Scavenging by Class B Receptors REACT:R-HSA-3000471
Scavenging by Class F Receptors REACT:R-HSA-3000484
Scavenging by Class H Receptors REACT:R-HSA-3000497
Scavenging of heme from plasma REACT:R-HSA-2168880
SCF-beta-TrCP mediated degradation of Emi1 REACT:R-HSA-174113
SCF-BTRC complex KEGG:hsa_M00380
SCF-FBS complex KEGG:hsa_M00382
SCF-FBW7 complex KEGG:hsa_M00387
SCF-SKP2 complex KEGG:hsa_M00381
SCF(Skp2)-mediated degradation of p27/p21 REACT:R-HSA-187577
Sec61 complex KEGG:hsa_M00401
Selenoamino acid metabolism REACT:R-HSA-2408522
Selenocompound metabolism KEGG:hsa00450
Selenocysteine synthesis REACT:R-HSA-2408557
Sema3A PAK dependent Axon repulsion REACT:R-HSA-399954
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion REACT:R-HSA-399955
Sema4D induced cell migration and growth-cone collapse REACT:R-HSA-416572
Sema4D in semaphorin signaling REACT:R-HSA-400685
Sema4D mediated inhibition of cell attachment and migration REACT:R-HSA-416550
Semaphorin interactions REACT:R-HSA-373755
SeMet incorporation into proteins REACT:R-HSA-2408517
Senescence-Associated Secretory Phenotype (SASP) REACT:R-HSA-2559582
Sensing of DNA Double Strand Breaks REACT:R-HSA-5693548
Separation of Sister Chromatids REACT:R-HSA-2467813
Serine biosynthesis REACT:R-HSA-977347
Serine biosynthesis, glycerate-3P => serine KEGG:hsa_M00020
Serotonergic synapse KEGG:hsa04726
Serotonin and melatonin biosynthesis REACT:R-HSA-209931
Serotonin clearance from the synaptic cleft REACT:R-HSA-380615
Serotonin Neurotransmitter Release Cycle REACT:R-HSA-181429
Serotonin receptors REACT:R-HSA-390666
Severe congenital neutropenia type 4 (G6PC3) REACT:R-HSA-3282872
SHC1 events in EGFR signaling REACT:R-HSA-180336
SHC1 events in ERBB2 signaling REACT:R-HSA-1250196
SHC1 events in ERBB4 signaling REACT:R-HSA-1250347
SHC-mediated cascade:FGFR1 REACT:R-HSA-5654688
SHC-mediated cascade:FGFR2 REACT:R-HSA-5654699
SHC-mediated cascade:FGFR3 REACT:R-HSA-5654704
SHC-mediated cascade:FGFR4 REACT:R-HSA-5654719
SHC-related events triggered by IGF1R REACT:R-HSA-2428933
Shelterin complex KEGG:hsa_M00424
Shigellosis KEGG:hsa05131
Sialic acid metabolism REACT:R-HSA-4085001
Signal amplification REACT:R-HSA-392518
Signal attenuation REACT:R-HSA-74749
Signaling by activated point mutants of FGFR1 REACT:R-HSA-1839122
Signaling by activated point mutants of FGFR3 REACT:R-HSA-1839130
Signaling by Activin REACT:R-HSA-1502540
Signaling by BMP REACT:R-HSA-201451
Signaling by BRAF and RAF fusions REACT:R-HSA-6802952
Signaling by cytosolic FGFR1 fusion mutants REACT:R-HSA-1839117
Signaling by EGFR REACT:R-HSA-177929
Signaling by EGFR in Cancer REACT:R-HSA-1643713
Signaling by EGFRvIII in Cancer REACT:R-HSA-5637812
Signaling by ERBB2 REACT:R-HSA-1227986
Signaling by ERBB4 REACT:R-HSA-1236394
Signaling by FGFR REACT:R-HSA-190236
Signaling by FGFR1 REACT:R-HSA-5654736
Signaling by FGFR1 amplification mutants REACT:R-HSA-1839120
Signaling by FGFR1 in disease REACT:R-HSA-5655302
Signaling by FGFR2 REACT:R-HSA-5654738
Signaling by FGFR2 amplification mutants REACT:R-HSA-2023837
Signaling by FGFR2 fusions REACT:R-HSA-8853333
Signaling by FGFR2 IIIa TM REACT:R-HSA-8851708
Signaling by FGFR2 in disease REACT:R-HSA-5655253
Signaling by FGFR3 REACT:R-HSA-5654741
Signaling by FGFR3 fusions in cancer REACT:R-HSA-8853334
Signaling by FGFR3 in disease REACT:R-HSA-5655332
Signaling by FGFR3 point mutants in cancer REACT:R-HSA-8853338
Signaling by FGFR4 REACT:R-HSA-5654743
Signaling by FGFR4 in disease REACT:R-HSA-5655291
Signaling by FGFR in disease REACT:R-HSA-1226099
Signaling by GPCR REACT:R-HSA-372790
Signaling by Hedgehog REACT:R-HSA-5358351
Signaling by high-kinase activity BRAF mutants REACT:R-HSA-6802948
Signaling by Hippo REACT:R-HSA-2028269
Signaling by Insulin receptor REACT:R-HSA-74752
Signaling by Interleukins REACT:R-HSA-449147
Signaling by Leptin REACT:R-HSA-2586552
Signaling by Ligand-Responsive EGFR Variants in Cancer REACT:R-HSA-5637815
Signaling by MET REACT:R-HSA-6806834
Signaling by moderate kinase activity BRAF mutants REACT:R-HSA-6802946
Signaling by MST1 REACT:R-HSA-8852405
Signaling by NODAL REACT:R-HSA-1181150
Signaling by NOTCH REACT:R-HSA-157118
Signaling by NOTCH1 REACT:R-HSA-1980143
Signaling by NOTCH1 HD Domain Mutants in Cancer REACT:R-HSA-2691230
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer REACT:R-HSA-2894858
Signaling by NOTCH1 in Cancer REACT:R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer REACT:R-HSA-2644602
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660825
Signaling by NOTCH2 REACT:R-HSA-1980145
Signaling by NOTCH3 REACT:R-HSA-1980148
Signaling by NOTCH4 REACT:R-HSA-1980150
Signaling by Overexpressed Wild-Type EGFR in Cancer REACT:R-HSA-5638302
Signaling by PDGF REACT:R-HSA-186797
Signaling by plasma membrane FGFR1 fusions REACT:R-HSA-8853336
Signaling by PTK6 REACT:R-HSA-8848021
Signaling by RAS mutants REACT:R-HSA-6802949
Signaling by Retinoic Acid REACT:R-HSA-5362517
Signaling by Rho GTPases REACT:R-HSA-194315
Signaling by Robo receptor REACT:R-HSA-376176
Signaling by SCF-KIT REACT:R-HSA-1433557
Signaling by TGF-beta Receptor Complex REACT:R-HSA-170834
Signaling by TGF-beta Receptor Complex in Cancer REACT:R-HSA-3304351
Signaling by the B Cell Receptor (BCR) REACT:R-HSA-983705
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) REACT:R-HSA-2404192
Signaling by VEGF REACT:R-HSA-194138
Signaling by Wnt REACT:R-HSA-195721
Signaling by WNT in cancer REACT:R-HSA-4791275
Signaling pathways regulating pluripotency of stem cells KEGG:hsa04550
Signalling by NGF REACT:R-HSA-166520
Signalling to ERK5 REACT:R-HSA-198765
Signalling to ERKs REACT:R-HSA-187687
Signalling to p38 via RIT and RIN REACT:R-HSA-187706
Signalling to RAS REACT:R-HSA-167044
Signalling to STAT3 REACT:R-HSA-198745
Signal regulatory protein (SIRP) family interactions REACT:R-HSA-391160
Signal Transduction REACT:R-HSA-162582
Signal transduction by L1 REACT:R-HSA-445144
SIRT1 negatively regulates rRNA Expression REACT:R-HSA-427359
Ski complex KEGG:hsa_M00392
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs REACT:R-HSA-77588
SLBP independent Processing of Histone Pre-mRNAs REACT:R-HSA-111367
SLC-mediated transmembrane transport REACT:R-HSA-425407
SLC transporter disorders REACT:R-HSA-5619102
SMAC binds to IAPs REACT:R-HSA-111463
SMAC-mediated apoptotic response REACT:R-HSA-111469
SMAC-mediated dissociation of IAP:caspase complexes REACT:R-HSA-111464
SMAD2/3 MH2 Domain Mutants in Cancer REACT:R-HSA-3315487
SMAD2/3 Phosphorylation Motif Mutants in Cancer REACT:R-HSA-3304356
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription REACT:R-HSA-2173796
SMAD4 MH2 Domain Mutants in Cancer REACT:R-HSA-3311021
Small cell lung cancer KEGG:hsa05222
Small interfering RNA (siRNA) biogenesis REACT:R-HSA-426486
Sm core complex KEGG:hsa_M00398
Smooth Muscle Contraction REACT:R-HSA-445355
SNARE interactions in vesicular transport KEGG:hsa04130
snRNP Assembly REACT:R-HSA-191859
Sodium/Calcium exchangers REACT:R-HSA-425561
Sodium-coupled phosphate cotransporters REACT:R-HSA-427652
Sodium-coupled sulphate, di- and tri-carboxylate transporters REACT:R-HSA-433137
Sodium/Proton exchangers REACT:R-HSA-425986
SOS-mediated signalling REACT:R-HSA-112412
Sperm Motility And Taxes REACT:R-HSA-1300642
Sperm:Oocyte Membrane Binding REACT:R-HSA-1300652
S Phase REACT:R-HSA-69242
Sphingolipid de novo biosynthesis REACT:R-HSA-1660661
Sphingolipid metabolism KEGG:hsa00600
Sphingolipid metabolism REACT:R-HSA-428157
Sphingolipid signaling pathway KEGG:hsa04071
Sphingosine biosynthesis KEGG:hsa_M00099
Sphingosine degradation KEGG:hsa_M00100
Spliceosome KEGG:hsa03040
Spliceosome, 35S U5-snRNP KEGG:hsa_M00355
Spliceosome, Prp19/CDC5L complex KEGG:hsa_M00353
Spliceosome, U1-snRNP KEGG:hsa_M00351
Spliceosome, U2-snRNP KEGG:hsa_M00352
Spliceosome, U4/U6.U5 tri-snRNP KEGG:hsa_M00354
Spry regulation of FGF signaling REACT:R-HSA-1295596
SRP-dependent cotranslational protein targeting to membrane REACT:R-HSA-1799339
Stabilization of p53 REACT:R-HSA-69541
Staphylococcus aureus infection KEGG:hsa05150
Starch and sucrose metabolism KEGG:hsa00500
STAT6-mediated induction of chemokines REACT:R-HSA-3249367
Steroid biosynthesis KEGG:hsa00100
Steroid hormone biosynthesis KEGG:hsa00140
Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone KEGG:hsa_M00107
Sterols are 12-hydroxylated by CYP8B1 REACT:R-HSA-211994
Stimulation of the cell death response by PAK-2p34 REACT:R-HSA-211736
Stimuli-sensing channels REACT:R-HSA-2672351
STING mediated induction of host immune responses REACT:R-HSA-1834941
Striated Muscle Contraction REACT:R-HSA-390522
Succinate dehydrogenase (ubiquinone) KEGG:hsa_M00148
Sulfide oxidation to sulfate REACT:R-HSA-1614517
Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid KEGG:hsa_M00067
Sulfur amino acid metabolism REACT:R-HSA-1614635
Sulfur metabolism KEGG:hsa00920
Sulfur relay system KEGG:hsa04122
SUMO E3 ligases SUMOylate target proteins REACT:R-HSA-3108232
SUMO is conjugated to E1 (UBA2:SAE1) REACT:R-HSA-3065676
SUMO is proteolytically processed REACT:R-HSA-3065679
SUMO is transferred from E1 to E2 (UBE2I, UBC9) REACT:R-HSA-3065678
SUMOylation REACT:R-HSA-2990846
SUMOylation of chromatin organization proteins REACT:R-HSA-4551638
SUMOylation of DNA damage response and repair proteins REACT:R-HSA-3108214
SUMOylation of DNA replication proteins REACT:R-HSA-4615885
SUMOylation of RNA binding proteins REACT:R-HSA-4570464
SUMOylation of transcription factors REACT:R-HSA-3232118
Surfactant metabolism REACT:R-HSA-5683826
Survival motor neuron (SMN) complex KEGG:hsa_M00426
Switching of origins to a post-replicative state REACT:R-HSA-69052
Synaptic vesicle cycle KEGG:hsa04721
Syndecan interactions REACT:R-HSA-3000170
Synthesis and degradation of ketone bodies KEGG:hsa00072
Synthesis and interconversion of nucleotide di- and triphosphates REACT:R-HSA-499943
Synthesis and processing of ENV and VPU REACT:R-HSA-171286
Synthesis And Processing Of GAG, GAGPOL Polyproteins REACT:R-HSA-174495
Synthesis of 12-eicosatetraenoic acid derivatives REACT:R-HSA-2142712
Synthesis of 15-eicosatetraenoic acid derivatives REACT:R-HSA-2142770
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) REACT:R-HSA-2142816
Synthesis of 5-eicosatetraenoic acids REACT:R-HSA-2142688
Synthesis of active ubiquitin: roles of E1 and E2 enzymes REACT:R-HSA-8866652
Synthesis of bile acids and bile salts REACT:R-HSA-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol REACT:R-HSA-193775
Synthesis of bile acids and bile salts via 27-hydroxycholesterol REACT:R-HSA-193807
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol REACT:R-HSA-193368
Synthesis of BMP REACT:R-HSA-1483171
Synthesis of CL REACT:R-HSA-1483076
Synthesis of diphthamide-EEF2 REACT:R-HSA-5358493
Synthesis of DNA REACT:R-HSA-69239
Synthesis of Dolichyl-phosphate REACT:R-HSA-446199
Synthesis of dolichyl-phosphate-glucose REACT:R-HSA-480985
Synthesis of dolichyl-phosphate mannose REACT:R-HSA-162699
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) REACT:R-HSA-2142670
Synthesis of GDP-mannose REACT:R-HSA-446205
Synthesis of glycosylphosphatidylinositol (GPI) REACT:R-HSA-162710
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) REACT:R-HSA-2142696
Synthesis of IP2, IP, and Ins in the cytosol REACT:R-HSA-1855183
Synthesis of IP3 and IP4 in the cytosol REACT:R-HSA-1855204
Synthesis of IPs in the ER lumen REACT:R-HSA-1855231
Synthesis of IPs in the nucleus REACT:R-HSA-1855191
Synthesis of Ketone Bodies REACT:R-HSA-77111
Synthesis of Leukotrienes (LT) and Eoxins (EX) REACT:R-HSA-2142691
Synthesis of Lipoxins (LX) REACT:R-HSA-2142700
Synthesis of PA REACT:R-HSA-1483166
Synthesis of PC REACT:R-HSA-1483191
Synthesis of PE REACT:R-HSA-1483213
Synthesis of PG REACT:R-HSA-1483148
Synthesis of PI REACT:R-HSA-1483226
Synthesis of PIPs at the early endosome membrane REACT:R-HSA-1660516
Synthesis of PIPs at the ER membrane REACT:R-HSA-1483248
Synthesis of PIPs at the Golgi membrane REACT:R-HSA-1660514
Synthesis of PIPs at the late endosome membrane REACT:R-HSA-1660517
Synthesis of PIPs at the plasma membrane REACT:R-HSA-1660499
Synthesis of PIPs in the nucleus REACT:R-HSA-8847453
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) REACT:R-HSA-2162123
Synthesis of PS REACT:R-HSA-1483101
Synthesis of pyrophosphates in the cytosol REACT:R-HSA-1855167
Synthesis of substrates in N-glycan biosythesis REACT:R-HSA-446219
Synthesis of UDP-N-acetyl-glucosamine REACT:R-HSA-446210
Synthesis of very long-chain fatty acyl-CoAs REACT:R-HSA-75876
Synthesis of wybutosine at G37 of tRNA(Phe) REACT:R-HSA-6782861
Synthesis, secretion, and deacylation of Ghrelin REACT:R-HSA-422085
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) REACT:R-HSA-381771
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) REACT:R-HSA-400511
Systemic lupus erythematosus KEGG:hsa05322
t(4;14) translocations of FGFR3 REACT:R-HSA-2033515
T41 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358752
Tachykinin receptors bind tachykinins REACT:R-HSA-380095
TAK1 activates NFkB by phosphorylation and activation of IKKs complex REACT:R-HSA-445989
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P REACT:R-HSA-6791462
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P REACT:R-HSA-6791055
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) REACT:R-HSA-1299308
Tandem pore domain halothane-inhibited K+ channel (THIK) REACT:R-HSA-1299287
Tandem pore domain potassium channels REACT:R-HSA-1296346
Taste transduction KEGG:hsa04742
Tat-mediated elongation of the HIV-1 transcript REACT:R-HSA-167246
Tat-mediated HIV elongation arrest and recovery REACT:R-HSA-167243
Taurine and hypotaurine metabolism KEGG:hsa00430
TBC/RABGAPs REACT:R-HSA-8854214
T cell receptor signaling pathway KEGG:hsa04660
TCF7L2 mutants don't bind CTBP REACT:R-HSA-5339700
TCF dependent signaling in response to WNT REACT:R-HSA-201681
TCR signaling REACT:R-HSA-202403
Telomere C-strand (Lagging Strand) Synthesis REACT:R-HSA-174417
Telomere C-strand synthesis initiation REACT:R-HSA-174430
Telomere Extension By Telomerase REACT:R-HSA-171319
Telomere Maintenance REACT:R-HSA-157579
Terminal pathway of complement REACT:R-HSA-166665
Termination of O-glycan biosynthesis REACT:R-HSA-977068
Termination of translesion DNA synthesis REACT:R-HSA-5656169
Terpenoid backbone biosynthesis KEGG:hsa00900
TET1,2,3 and TDG demethylate DNA REACT:R-HSA-5221030
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation REACT:R-HSA-1474151
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation REACT:R-HSA-8869496
TFAP2 (AP-2) family regulates transcription of cell cycle factors REACT:R-HSA-8866911
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors REACT:R-HSA-8866910
TFAP2 (AP-2) family regulates transcription of other transcription factors REACT:R-HSA-8866906
TGF-beta receptor signaling activates SMADs REACT:R-HSA-2173789
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) REACT:R-HSA-2173791
TGF-beta signaling KEGG:hsa_M00680
TGF-beta signaling pathway KEGG:hsa04350
TGFBR1 KD Mutants in Cancer REACT:R-HSA-3656532
TGFBR1 LBD Mutants in Cancer REACT:R-HSA-3656535
TGFBR2 Kinase Domain Mutants in Cancer REACT:R-HSA-3645790
TGFBR2 MSI Frameshift Mutants in Cancer REACT:R-HSA-3642279
Th17 cell differentiation KEGG:hsa04659
Th1 and Th2 cell differentiation KEGG:hsa04658
THC complex KEGG:hsa_M00405
The activation of arylsulfatases REACT:R-HSA-1663150
The AIM2 inflammasome REACT:R-HSA-844615
The canonical retinoid cycle in rods (twilight vision) REACT:R-HSA-2453902
The citric acid (TCA) cycle and respiratory electron transport REACT:R-HSA-1428517
The fatty acid cycling model REACT:R-HSA-167826
The IPAF inflammasome REACT:R-HSA-844623
The NLRP1 inflammasome REACT:R-HSA-844455
The NLRP3 inflammasome REACT:R-HSA-844456
The phototransduction cascade REACT:R-HSA-2514856
The proton buffering model REACT:R-HSA-167827
The retinoid cycle in cones (daylight vision) REACT:R-HSA-2187335
The role of GTSE1 in G2/M progression after G2 checkpoint REACT:R-HSA-8852276
The role of Nef in HIV-1 replication and disease pathogenesis REACT:R-HSA-164952
Thiamine metabolism KEGG:hsa00730
Threonine catabolism REACT:R-HSA-8849175
Thrombin signalling through proteinase activated receptors (PARs) REACT:R-HSA-456926
Thromboxane signalling through TP receptor REACT:R-HSA-428930
Thyroid cancer KEGG:hsa05216
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine KEGG:hsa_M00043
Thyroid hormone signaling pathway KEGG:hsa04919
Thyroid hormone synthesis KEGG:hsa04918
Thyroxine biosynthesis REACT:R-HSA-209968
TICAM1 deficiency - HSE REACT:R-HSA-5602566
Tie2 Signaling REACT:R-HSA-210993
Tight junction KEGG:hsa04530
Tight junction interactions REACT:R-HSA-420029
TLR3 deficiency - HSE REACT:R-HSA-5602410
TNFR1-induced NFkappaB signaling pathway REACT:R-HSA-5357956
TNFR1-induced proapoptotic signaling REACT:R-HSA-5357786
TNFR1-mediated ceramide production REACT:R-HSA-5626978
TNFR2 non-canonical NF-kB pathway REACT:R-HSA-5668541
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway REACT:R-HSA-5676594
TNFs bind their physiological receptors REACT:R-HSA-5669034
TNF signaling REACT:R-HSA-75893
TNF signaling pathway KEGG:hsa04668
Tolerance by Mtb to nitric oxide produced by macrophages REACT:R-HSA-1222538
Tolerance of reactive oxygen produced by macrophages REACT:R-HSA-1222387
Toll Like Receptor 10 (TLR10) Cascade REACT:R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade REACT:R-HSA-181438
Toll Like Receptor 3 (TLR3) Cascade REACT:R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade REACT:R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade REACT:R-HSA-168176
Toll Like Receptor 7/8 (TLR7/8) Cascade REACT:R-HSA-168181
Toll Like Receptor 9 (TLR9) Cascade REACT:R-HSA-168138
Toll-Like Receptors Cascades REACT:R-HSA-168898
Toll-like receptor signaling KEGG:hsa_M00686
Toll-like receptor signaling pathway KEGG:hsa04620
Toll Like Receptor TLR1:TLR2 Cascade REACT:R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade REACT:R-HSA-168188
Toxicity of botulinum toxin type A (BoNT/A) REACT:R-HSA-5250968
Toxicity of botulinum toxin type B (BoNT/B) REACT:R-HSA-5250958
Toxicity of botulinum toxin type C (BoNT/C) REACT:R-HSA-5250971
Toxicity of botulinum toxin type D (BoNT/D) REACT:R-HSA-5250955
Toxicity of botulinum toxin type E (BoNT/E) REACT:R-HSA-5250992
Toxicity of botulinum toxin type F (BoNT/F) REACT:R-HSA-5250981
Toxicity of botulinum toxin type G (BoNT/G) REACT:R-HSA-5250989
Toxicity of tetanus toxin (TeNT) REACT:R-HSA-5250982
Toxoplasmosis KEGG:hsa05145
TP53 Regulates Metabolic Genes REACT:R-HSA-5628897
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain REACT:R-HSA-6804115
TP53 Regulates Transcription of Caspase Activators and Caspases REACT:R-HSA-6803207
TP53 Regulates Transcription of Cell Cycle Genes REACT:R-HSA-6791312
TP53 Regulates Transcription of Cell Death Genes REACT:R-HSA-5633008
TP53 Regulates Transcription of Death Receptors and Ligands REACT:R-HSA-6803211
TP53 Regulates Transcription of DNA Repair Genes REACT:R-HSA-6796648
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release REACT:R-HSA-6803204
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest REACT:R-HSA-6804116
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest REACT:R-HSA-6804114
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain REACT:R-HSA-6803205
TRAF3 deficiency - HSE REACT:R-HSA-5602571
TRAF3-dependent IRF activation pathway REACT:R-HSA-918233
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation REACT:R-HSA-975138
TRAF6 mediated induction of TAK1 complex REACT:R-HSA-937072
TRAF6 mediated IRF7 activation REACT:R-HSA-933541
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling REACT:R-HSA-975110
TRAF6 mediated NF-kB activation REACT:R-HSA-933542
Trafficking and processing of endosomal TLR REACT:R-HSA-1679131
Trafficking of AMPA receptors REACT:R-HSA-399719
Trafficking of dietary sterols REACT:R-HSA-265473
Trafficking of GluR2-containing AMPA receptors REACT:R-HSA-416993
Trafficking of myristoylated proteins to the cilium REACT:R-HSA-5624138
TRAIL signaling REACT:R-HSA-75158
TRAMP complex KEGG:hsa_M00393
Transcriptional activation of cell cycle inhibitor p21 REACT:R-HSA-69895
Transcriptional activation of mitochondrial biogenesis REACT:R-HSA-2151201
Transcriptional activation of p53 responsive genes REACT:R-HSA-69560
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer REACT:R-HSA-2173793
Transcriptional misregulation in cancer KEGG:hsa05202
Transcriptional regulation by small RNAs REACT:R-HSA-5578749
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors REACT:R-HSA-8864260
Transcriptional Regulation by TP53 REACT:R-HSA-3700989
Transcriptional regulation of pluripotent stem cells REACT:R-HSA-452723
Transcriptional regulation of white adipocyte differentiation REACT:R-HSA-381340
Transcription-Coupled Nucleotide Excision Repair (TC-NER) REACT:R-HSA-6781827
Transcription from mitochondrial promoters REACT:R-HSA-75944
Transcription of the HIV genome REACT:R-HSA-167172
Transfer of LPS from LBP carrier to CD14 REACT:R-HSA-166020
Transferrin endocytosis and recycling REACT:R-HSA-917977
trans-Golgi Network Vesicle Budding REACT:R-HSA-199992
Translation REACT:R-HSA-72766
Translation initiation complex formation REACT:R-HSA-72649
Translesion Synthesis by POLH REACT:R-HSA-110320
Translesion synthesis by POLI REACT:R-HSA-5656121
Translesion synthesis by POLK REACT:R-HSA-5655862
Translesion synthesis by REV1 REACT:R-HSA-110312
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template REACT:R-HSA-110313
Translocation of GLUT4 to the plasma membrane REACT:R-HSA-1445148
Translocation of ZAP-70 to Immunological synapse REACT:R-HSA-202430
Translocon-associated protein (TRAP) complex KEGG:hsa_M00402
Transmembrane transport of small molecules REACT:R-HSA-382551
Transmission across Chemical Synapses REACT:R-HSA-112315
Transmission across Electrical Synapses REACT:R-HSA-112307
Transport and synthesis of PAPS REACT:R-HSA-174362
Transport of connexins along the secretory pathway REACT:R-HSA-190827
Transport of connexons to the plasma membrane REACT:R-HSA-190872
Transport of fatty acids REACT:R-HSA-804914
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus REACT:R-HSA-159763
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds REACT:R-HSA-425366
Transport of glycerol from adipocytes to the liver by Aquaporins REACT:R-HSA-432030
Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus REACT:R-HSA-168874
Transport of inorganic cations/anions and amino acids/oligopeptides REACT:R-HSA-425393
Transport of Mature mRNA derived from an Intron-Containing Transcript REACT:R-HSA-159236
Transport of Mature mRNA Derived from an Intronless Transcript REACT:R-HSA-159231
Transport of Mature mRNAs Derived from Intronless Transcripts REACT:R-HSA-159234
Transport of Mature Transcript to Cytoplasm REACT:R-HSA-72202
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane REACT:R-HSA-83936
Transport of nucleotide sugars REACT:R-HSA-727802
Transport of organic anions REACT:R-HSA-879518
Transport of Ribonucleoproteins into the Host Nucleus REACT:R-HSA-168271
Transport of the SLBP Dependant Mature mRNA REACT:R-HSA-159230
Transport of the SLBP independent Mature mRNA REACT:R-HSA-159227
Transport of vitamins, nucleosides, and related molecules REACT:R-HSA-425397
Transport to the Golgi and subsequent modification REACT:R-HSA-948021
TREX complex KEGG:hsa_M00406
Triacylglycerol biosynthesis KEGG:hsa_M00089
TRIF-mediated programmed cell death REACT:R-HSA-2562578
TRIF-mediated TLR3/TLR4 signaling REACT:R-HSA-937061
Triglyceride Biosynthesis REACT:R-HSA-75109
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA REACT:R-HSA-450513
TRKA activation by NGF REACT:R-HSA-187042
tRNA Aminoacylation REACT:R-HSA-379724
tRNA modification in the mitochondrion REACT:R-HSA-6787450
tRNA modification in the nucleus and cytosol REACT:R-HSA-6782315
tRNA processing REACT:R-HSA-72306
tRNA processing in the mitochondrion REACT:R-HSA-6785470
tRNA processing in the nucleus REACT:R-HSA-6784531
TRP channels REACT:R-HSA-3295583
truncated APC mutants destabilize the destruction complex REACT:R-HSA-4839744
Truncations of AMER1 destabilize the destruction complex REACT:R-HSA-5467348
Tryptophan catabolism REACT:R-HSA-71240
Tryptophan metabolism KEGG:hsa00380
Tuberculosis KEGG:hsa05152
TWIK-related alkaline pH activated K+ channel (TALK) REACT:R-HSA-1299361
TWIK related potassium channel (TREK) REACT:R-HSA-1299503
TWIK-related spinal cord K+ channel (TRESK) REACT:R-HSA-1299344
TWIK-releated acid-sensitive K+ channel (TASK) REACT:R-HSA-1299316
Type I diabetes mellitus KEGG:hsa04940
Type I hemidesmosome assembly REACT:R-HSA-446107
Type II diabetes mellitus KEGG:hsa04930
Type II Na+/Pi cotransporters REACT:R-HSA-427589
Tyrosine degradation, tyrosine => homogentisate KEGG:hsa_M00044
Tyrosine metabolism KEGG:hsa00350
Ubiquinol biosynthesis REACT:R-HSA-2142789
Ubiquinone and other terpenoid-quinone biosynthesis KEGG:hsa00130
Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone KEGG:hsa_M00128
Ubiquitin-dependent degradation of Cyclin D REACT:R-HSA-75815
Ubiquitin-dependent degradation of Cyclin D1 REACT:R-HSA-69229
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A REACT:R-HSA-69601
Ubiquitin mediated proteolysis KEGG:hsa04120
Ub-specific processing proteases REACT:R-HSA-5689880
UCH proteinases REACT:R-HSA-5689603
Unblocking of NMDA receptor, glutamate binding and activation REACT:R-HSA-438066
UNC93B1 deficiency - HSE REACT:R-HSA-5602415
Uncoating of the HIV Virion REACT:R-HSA-162585
Uncoating of the Influenza Virion REACT:R-HSA-168336
Unfolded Protein Response (UPR) REACT:R-HSA-381119
Unwinding of DNA REACT:R-HSA-176974
Uptake and actions of bacterial toxins REACT:R-HSA-5339562
Uptake and function of anthrax toxins REACT:R-HSA-5210891
Uptake and function of diphtheria toxin REACT:R-HSA-5336415
Urea cycle KEGG:hsa_M00029
Urea cycle REACT:R-HSA-70635
Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP KEGG:hsa_M00051
Utilization of Ketone Bodies REACT:R-HSA-77108
Valine, leucine and isoleucine biosynthesis KEGG:hsa00290
Valine, leucine and isoleucine degradation KEGG:hsa00280
Variant SLC6A14 may confer susceptibility towards obesity REACT:R-HSA-5619094
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5619101
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5660686
Vascular smooth muscle contraction KEGG:hsa04270
Vasopressin-like receptors REACT:R-HSA-388479
Vasopressin-regulated water reabsorption KEGG:hsa04962
Vasopressin regulates renal water homeostasis via Aquaporins REACT:R-HSA-432040
VEGFA-VEGFR2 Pathway REACT:R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization REACT:R-HSA-195399
VEGF ligand-receptor interactions REACT:R-HSA-194313
VEGFR2 mediated cell proliferation REACT:R-HSA-5218921
VEGFR2 mediated vascular permeability REACT:R-HSA-5218920
VEGF signaling pathway KEGG:hsa04370
Vesicle-mediated transport REACT:R-HSA-5653656
Vibrio cholerae infection KEGG:hsa05110
Vif-mediated degradation of APOBEC3G REACT:R-HSA-180585
Viral carcinogenesis KEGG:hsa05203
Viral Messenger RNA Synthesis REACT:R-HSA-168325
Viral mRNA Translation REACT:R-HSA-192823
Viral myocarditis KEGG:hsa05416
Viral RNP Complexes in the Host Cell Nucleus REACT:R-HSA-168330
Virus Assembly and Release REACT:R-HSA-168268
Visual phototransduction REACT:R-HSA-2187338
Vitamin B1 (thiamin) metabolism REACT:R-HSA-196819
Vitamin B2 (riboflavin) metabolism REACT:R-HSA-196843
Vitamin B5 (pantothenate) metabolism REACT:R-HSA-199220
Vitamin B6 metabolism KEGG:hsa00750
Vitamin C (ascorbate) metabolism REACT:R-HSA-196836
Vitamin D (calciferol) metabolism REACT:R-HSA-196791
Vitamin digestion and absorption KEGG:hsa04977
Vitamins REACT:R-HSA-211916
Vitamins B6 activation to pyridoxal phosphate REACT:R-HSA-964975
VLDL biosynthesis REACT:R-HSA-8866423
VLDL interactions REACT:R-HSA-8855121
VLDLR internalisation and degradation REACT:R-HSA-8866427
Voltage gated Potassium channels REACT:R-HSA-1296072
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization REACT:R-HSA-180897
Vpr-mediated nuclear import of PICs REACT:R-HSA-180910
Vpu mediated degradation of CD4 REACT:R-HSA-180534
vRNA Synthesis REACT:R-HSA-192814
vRNP Assembly REACT:R-HSA-192905
V-type ATPase, eukaryotes KEGG:hsa_M00160
VxPx cargo-targeting to cilium REACT:R-HSA-5620916
Wax biosynthesis REACT:R-HSA-8848584
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 REACT:R-HSA-5140745
WNT5A-dependent internalization of FZD4 REACT:R-HSA-5099900
WNT ligand biogenesis and trafficking REACT:R-HSA-3238698
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 REACT:R-HSA-5340573
WNT mediated activation of DVL REACT:R-HSA-201688
Wnt signaling KEGG:hsa_M00677
Wnt signaling pathway KEGG:hsa04310
XAV939 inhibits tankyrase, stabilizing AXIN REACT:R-HSA-5545619
XBP1(S) activates chaperone genes REACT:R-HSA-381038
Xenobiotics REACT:R-HSA-211981
YAP1- and WWTR1 (TAZ)-stimulated gene expression REACT:R-HSA-2032785
ZBP1(DAI) mediated induction of type I IFNs REACT:R-HSA-1606322
Zinc efflux and compartmentalization by the SLC30 family REACT:R-HSA-435368
Zinc influx into cells by the SLC39 gene family REACT:R-HSA-442380
Zinc transporters REACT:R-HSA-435354
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