Eachan Johnson
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metadata
license: mit
task_categories:
  - fill-mask
  - text-classification
  - text2text-generation
  - translation
  - zero-shot-classification
tags:
  - chemistry
  - biology
  - synthetic
  - SMILES
size_categories:
  - 10M<n<100M
pretty_name: Cyclic peptides (70 million)
configs:
  - config_name: full
    data_files: '*/*.csv.gz'
    default: true
  - config_name: split
    data_files:
      - split: train
        path: train/*.csv.gz
      - split: test
        path: test/*.csv.gz
      - split: validation
        path: validation/*.csv.gz

cyc-pep-6-12mer-70M-2024

Set of 70 million (almost) unique cyclic and linear peptides comprising 6-12 amino acids, each with some calculated molecular properties.

Dataset Details

Dataset Description

  • Curated by: @eachanjohnson
  • Funded by: The Francis Crick Institute
  • License: MIT

Dataset Sources

  • Repository: https://huggingface.co/datasets/scbirlab/cyc-pep-6-12mer-70M-2024

    Dataset Structure

    • linear_id: Identifier for linear peptide
    • peptide_sequence: Amino acid sequence of linear peptide
    • SMILES: SMILES string of linear peptide
    • cyclic_id: Identifier for cyclic peptide
    • cyclic_inchikey: Unique identifier for cyclic peptide
    • cysteine_to_N_cyclization: SMILES string of cyclic peptide
    • cyclic_scaffold: Murcko scaffold of cyclic peptide
    • cyclic_mwt: Molecular weight of cyclic peptide
    • cyclic_clogp: Crippen LogP of cyclic peptide
    • cyclic_tpsa: Topological polar surface area of cyclic peptide

    Dataset Creation

    Curation Rationale

    To develop a large dataset of SMILES strings for peptides.

    Data Collection and Processing

    Data were generated using schemist, a tool for processing chemical datasets.

    Who are the source data producers?

    Eachan Johnson (@eachanjohnson).

    Personal and Sensitive Information

    None

    Dataset Card Contact

    @eachanjohnson