Emma Frost

* Abigail Brand - they cooperate since Breakworld (from Ast X-Men #19)
* Abomination - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Absorbing Man - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Amanda Sefton - Emma and the Hellfire club capture Amanda in X-Men #151-152
* Angel - they had to join forces (X-Men #281-282), later both X-Men (from #413)
* Anole - residents at the X-Mansion at the same time
* Armor - Armor was at the X-mansion, and both X-Men (from Ast X-Men #3.19)
* Artie Maddicks - he is adopted by Generation X
* Banshee - they brushed into each other when Emma was very young (retcon of Generation X #-1), in modern time he is co-headmaster at her institute, training Generation X
* Baron Mordo - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Batroc - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Beast *- Enemy:*conflicts with the X-Men *- Ally:* members of X-Men
* Bishop - they meet (X-Men #282-283) and they clash over the mutant Jeffrey Garrett (X-Treme X-Men #22-23)
* Black Bolt - Emma creates the image of Bolt in Ast X-Men #3.14
* Black Panther - Storm talks of Black Panther in Ast X-Men #3.25
* Blastaar - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Blindfold - residing at the X-Mansion at the same time
* Boom-Boom - they meet when X-Force visit the Massachussets academy (XF #42)
* Cable - Emma discusses Cable's merits when Warpath comes for a visit (X-Force #42), and they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Cannonball - *Enemy:* Emma and New Mutants battled in her Academy (NM #15-16) - *Ally*: he is enrolled in the Massachussets Academy (#38-40), later they meet on uncertain terms (New Mutants #53, 75)
* Captain America - Emma visualises Cap in Ast X-Men #3.14
* Celeste Cuckoo - Emma is biological mother and guardian of the sisters
* Chamber - in Generation X at her institute in Boston
* Charles Xavier - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129) - *Ally:* they have to join forces (X-Men #281-282), later cooperate around the institutes, even X-Men at the same time but in different teams (from around X-Men #409)
* Colossus - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129) - *Ally:* they have to join forces in U X-Men #281-282 and members from Ast X-Men #3.5
* Corsair - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Cyclops - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129) *- Ally:* members of X-Men. They have a psychic affair (New X-Men #136), and lovers
* Deadpool - Warpath talks about Deadpool when he visits Emma's institute (X-Force #42)
* Doctor Doom - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Doctor Octopus - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Doctor Strange - Nightmare talks about Strange when he comes to Emma for help (Generation X #22)
* Domino - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Doug Ramsey - *Enemy:* Doug was enrolled and manipulated in the Massachussets school (New Mutants #15) - *Ally*: again enrolled in the Massachussets Academy (NM #38-40), later they meet on uncertain terms in the Hellfire Club (#53)
* Dust - they meet outside the X-Mansion in All-New X-Men #10
* Electro - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Elixir - residents at the X-Mansion at the same time
* Firestar - Emma recruited Angelica to the Hellions as young kid (shown in New Warriors An. #1)
* Forge - they join forces in U X-Men #281-282, but clash in Forge's lair in Ast X-Men #3.29-3.30
* Franklin Richards - he is adopted by Generation X
* Gambit - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Genesis - they meet outside the X-Mansion in All-New X-Men #10
* Glob Herman - both residents at the X-Mansion
* Guardian - Emma is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Havok - they have met in Hellfire Club (X-Men #219), later both reside in the Xavier Institute (from #420)
* Hellion - residents at the X-Mansion at the same time
* Hepzibah - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* High Evolutionary - Armor mentions the Evolutionary in Ast X-Men #29
* Hobgoblin - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Human Torch - their two teams join forces against a monster in Ast X-Men #7
* Husk - she is member of Emma's Generation X, later both at the X-Mansion (from around X-Men #410)
* Iceman - they have to join forces (X-Men #281-282), but she also takes over his mind (#314), later both are X-Men (from #413)
* Iron-Man - alternate universe (Excalibur #21)
* J. Jonah Jameson - Emma talks about him in Ast X-Men #3.7
* Jean Grey - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129), later Jean inhabits Emma's body(#282) - *Ally*: Both members of X-Men
* Jubilee - Jubilee is in Generation X at Emma's institute
* Juggernaut - they both take part in the big fight of villains against Beyonder (Secret Wars II.7), and both residing at the X-Mansion (from X-Men #413)
* Kang - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Karma - first Shian is enrolled in the Massachussets Academy (#38-40), they also meet on uncertain terms in the Hellfire Club (New Mutants #53)
* Kid Omega - residents at the X-Mansion
* Kraven the Hunter - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Leech - he is adopted by Generation X
* Living Laser - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Magik - *Enemy:* Emma battled the New Mutants and Magik in the Mass. Academy (NM #15-16) - *Ally:* Magik joins the Academy (NM #39-40), they meet again on uncertain terms (#53, 75), later part of X-Men Extinction team (from All-New X-Men #3)
* Magma - *Enemy:* Emma battled the New Mutants in the Mass. Academy (NM #15-16) - *Ally*: Magma is enrolled in the Massachussets Academy several times (NM #38-40 and from #57). Nickname: "Amara Dear" (NM #62)
* Magneto - Emma pays a surprise visit to Xavier's mansion (New Mutants #38), Magneto then forges a pact with Hellfire Club (from X-Men #210), later members of X-Men Extinction team (from All-New X-Men #3). Nickname: "Old Man" (NM #38)
* Marvel Boy - Emma had met with New Warriors (shown in NW An. #1)
* Mastermind - *Ally:* they were in Hellfire Club together (from before X-Men #129). *Enemy:* he destroyed Emma telepathically (XM #175)
* Mephisto - Mephisto recruits her to fight against The Beyonder (Secret Wars II.7)
* Mercury - residents at the X-Mansion at the same time
* Mindee Cuckoo - Emma is biological mother and guardian of the sisters
* Mirage - *Enemy:* Emma battled the New Mutants in the Mass. Academy (NM #15-16), later they meet on uncertain terms (#38, 53, 75)
* Moira MacTaggert - she knows Moira through Banshee (e.g. Excalibur #115)
* Mole Man - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Monet - she is member of Emma's Generation X teen academy
* Multiple Man - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Namorita - Emma had met with New Warriors (shown in NW An. #1)
* Nick Fury - Fury is guardng Emma's Breakworld adventures with X-Men (from Ast X-Men #3.1)
* Nightcrawler - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129) - *Ally:* both X-Men (from #413)
* Nightmare - Nightmare visits Emma at her academy to ask for help (Generation X #22)
* Night Thrasher - Emma had met with New Warriors (shown in NW An. #1)
* Northstar - members of X-Men (from #414)
* Nova (Richard Rider) - Emma had met with New Warriors (shown in NW An. #1)
* Oya - they meet outside the X-Mansion in All-New X-Men #10
* Phoebe Cuckoo - Emma is biological mother and guardian of the sisters
* Pixie - residents at the X-Mansion at the same time
* Polaris - Emma sees Lorna as she studies Banshees memories (Generation X #28), later both are briefly residents at the X-Mansion (X-Men #418-421)
* Psylocke - Emma feels the global psionic pulse Psylocke emits when tricked by Shadow King (X-Men #2.77)
* Puck - Emma is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Quicksilver - they possibly meet at the wedding of Havok and Polaris (X-Men #425)
* Rachel Summers - alternate universe (Excalibur #22)
* Reed Richards - young Emma hears about a Richards patent (as retold in Generation X #-1), Emma is with Franklin after his parents "died", later their two teams join forces against a monster in Ast X-Men #7
* Rhino - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Rockslide - residents at the X-Mansion at the same time
* Rogue - Emma and X-Men have conflicts
* Sabretooth - Hellfire Club see Sabretooth slain at the X-Mansion (New Mutants #75)
* Sasquatch - Emma is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Sauron - the X-Men discuss Sauron in Ast X-Men #3.34
* Scarlet Witch - they possibly meet at the wedding of Havok and Polaris (X-Men #425), later Beast talks of Scarlet Witch (Ast X-Men #3.25)
* Sebastian Shaw - they were in Hellfire Club together (from before X-Men #129 to New Mutants #75)
* Selene - Selene joins Hellfire Club (New Mutants #22), later Emma gets mixed up in her new schemes against the X-Men (U X-Men #283)
* Shadowcat *- Enemy:* archenemy ever since Kitty was discovered (X-Men #129) *- Ally:* members of X-Men (from Astonishing XM #3.1). Nicknames: "Dear Heart" (New Mutants #15, 16), "Kitten" (#17)
* Siryn - they meet when X-Force visit the Massachussets academy (XF #42)
* Skin - Emma is principal and team leader for the kids in Generation X
* Snowbird - Emma is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Speedball - Emma had met with New Warriors (shown in NW An. #1)
* Spider-Man - Emma talks about him in Ast X-Men #3.7
* Storm - *Enemy:* iconic foe starting with the Dark Phoenix saga (X-Men #129). Emma even forced a mind-swap (#151) - *Ally:* Storm accompanies Magneto into Hellfire Club (New Mutants #51), they join forces in #281-282, later both members of X-Men (first on rival teams, later from Ast X-Men #25)
* Sunspot - *Enemy:* Emma battled the New Mutants in the Mass. Academy (NM #15-16), later they meet at the ruins of the X-Mansion (#75)
* Surge - residents at the X-Mansion at the same time
* Susan Richards - Emma is with Franklin after his parents "died", later their two teams join forces against a monster in Ast X-Men #7
* Synch - he is member of Emma's Generation X teen academy
* Tessa - they must have been in Hellfire Club together in the early days (before X-Men #132). An old photo of them together is shown (X-Treme X-Men #21[retcon]). Later they are on rival X-Men teams and clash over the mutant Jeffrey Garrett (X-Treme X-Men #22)
* The Thing The Thing - *Enemy*: Thing fights against all the villains that attack The Beyonder (Secret Wars II.7) - *Ally:* their two teams join forces against a monster in Ast X-Men #7
* Titania - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Vanisher - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Vindicator - Emma is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Vulture - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Warlock - they meet when the other New Mutants depart her academay (NM #40), again at the ruins of the X-Mansion (New Mutants #75)
* Warpath - he was in her Hellions group
* Wizard - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)
* Wolfsbane - *Enemy:* Emma battled the New Mutants in the Mass. Academy (NM #15-16 - *Ally*: Rahne is enrolled in the Massachussets Academy (NM #38-40), later they meet on uncertain terms (#53, 75). Nickname: "Little One" and "Young Lady" (NM #39)
* Wolverine - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129) *- Ally:* Wolverine visits the Massachussets institute several times (W #94, 141), later members of X-Men. Nickname: "Mad Man" (XM #152)
* Wrecker - they both take part in the big fight of villains against Beyonder (Secret Wars II.7)