Only One Setting/Anime and Manga

* The first 23 episodes of Kill la Kill are mostly set in Honno Town. The 24th episode subverts this, and in the 25th (the OVA), Honno Town, the primary setting for most of the episodes, sinks into the ocean.
* Soul Eater takes place almost entirely in Death City. Needless to say, there are some exceptions to this trope in that anime...
* Lucky Star in manga form takes place almost entirely in the girls' hometown, but their school is the most prominent setting in the series. This is lessened a little in the anime.
* Aggretsuko takes place almost entirely at Retsuko's workplace or the karaoke bar (depending on Retsuko's feelings). Keep in mind, this is only for most of the 2016 shorts. The Netflix series as a whole subverts this due to being an expansion of some of the original shorts and actually showing why Retsuko is the way she is.
* Had Ruby not been careless during Cleaning Day, the entirety of *Jewelpet* might've only taken place in Jewel Land.
* Mon Colle Knights has only two established settings: the hometown of Mondo and Rockna (with sub-settings being their school, the lab, and Prince Ludwig Von Monsterstein Eccentro's castle), and Mon World.
* Digimon as a whole averts this. But it seems outside of the Digital World, the Chosen Children of both *Adventure* and *Adventure 02* don't go outside their hometown. Averted by Tri, due to the Digimon franchise shifting towards Level 2 of the Cartoon Appropriateness Scale by that point.
* While averted in the games (and the original Japanese order for the anime), in the English dub of the anime, each specific region in Pokémon (prior to the end of Sun & Moon Ultra Legends, that is) is the only setting of a given season.
	+ Played even more straight for the "Sun & Moon" seasons. Granted, this is more due to Gyms being replaced with Island Trials and the amount of characters the anime has now.
	+ Last but not least, this got so bad that *Journeys* actually *averts* this by showcasing *every* region featured up to that point. As does the send-off series of specials showcasing the end of Ash's quest.
	+ According to what little information was available at the time, the anime after *Journeys* seemed to take place entirely in Paldea. However, this has since been headed for a potential aversion; more info released over the following months revealed that *Horizons* (the English title for the new series) is also destined to be a series similar to *Journeys*.
* *Angel Beats!* takes place almost entirely at a school that just happened to be part of the characters' afterlife.
	+ In fact, a lot of works by Key are most prominently set at a school. The only exception thus far is *Air*, since it takes place during summer.
* *Himouto! Umaru-chan* takes place almost entirely in Umaru's hometown. But not the entire story, since it would get too formulaic.
* The first season of *Maple Town* takes place almost entirely at the titular town. Likewise, its second season takes place in Palm Town.
* *Prison School* took place almost entirely at Hachimitsu Academy's prison block.
* *Bakuman* never could've really focused on story settings outside of Tokyo, since the Chiyoda ward is where Shueisha is located- averted with actual locations, at any rate.
* One of Kokoro's biggest obstacles to keeping her secret is the fact that her hometown is the most prominent setting in the entire show.
* *One Piece* only has one specific setting for each arc. As of 2019, that specific setting is Wano Country. Averted for the series as a whole.
* Namek in *Dragon Ball Z* is the most predominant setting in the entire Frieza saga- every other arc after tends to be one that can change location and scenery.
	+ In *Dragon Ball Z Abridged*, Krillin lampshades this by saying "We're *still* on Namek!".
* Not counting the dreams Yume and Mew enter, *Mewkledreamy* takes place almost exclusively in Yume's hometown.
* Doraemon: The Japanese version (especially for the 1979 anime) tends to avert it, running so long that the characters have obviously been outside of their hometown before. The 52 half-hour English dub, where most of the dubbed episodes took place entirely in Noby's hometown, *still* averts this at times, especially if the plot of the episode required going to space.
	+ The Moving Map *can* count as a tool used to avert this. Quote Sneech, "We could even bring stuff here from other countries." What he meant, of course, were said countries' landmarks.