Mister Sinister

## Nathaniel Essex / Mister Sinister

* Angel - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* Apocalypse - they cross paths in X-Cutioner's Song (U X-Men #294-295)
* Banshee - Sinister has his DNA in his collection (X-Men #2.52)
* Beast - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), later they clash over the fate of Threnody in Los Angeles (X-Men #2.27) and several other battles
* Bishop - *Enemy:* they fight in the X-Mansion in X-Cutioner's Song (X-Force #16) and later (X-Men #2.52)
* Cable - he holds the baby Nathan captive during Inferno (X-Men #239-243)
* Caliban - they maybe cross paths in X-Cutioner's Song (U X-Men #294-295)
* Charles Xavier - Sinister talks of Xavier many times (X-Men #240 and #2.27, X-Force #16)
* Colossus - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), and X-Men battle Sinister again on the space station of the High Evolutionary (X-Men #380)
* Cyclops - *Enemy:* Sinister manipulated Scott's youth, later the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* Dazzler - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* Gambit - *Enemy:* they have an early fight (X-Men #2.52), and X-Men battle Sinister again on the space station of the High Evolutionary (X-Men #380) - *Ally:* apparently Remy had been the link between Sinister and the Marauders (X-Men UL #18)
* Havok - *Enemy:* Sinister manipulated Alex's youth (retold in X-Factor #-1), later the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* High Evolutionary - apparently they have worked together as young men (X-Men #380[retcon]), but later Sinister holds him captured on his space station (#380)
* Iceman - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), later they clash over the fate of Threnody in Los Angeles (X-Men #2.27), and in space (X-Men #380)
* Jean Grey - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), and X-Men battle Sinister again on the space station of the High Evolutionary (X-Men #380)
* Jubilee - *Enemy:* they fight in the X-Mansion in X-Cutioner's Song (X-Force #16)
* Longshot - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* Madelyne Pryor - he originally created her, they are finally confronted in Inferno (#240-243)
* Marrow - *Enemy*: X-Men defeat Sinister on the space station of the High Evolutionary (X-Men #380)
* Multiple Man - *Enemy*: Sinister spies and plots against the new team X-Factor (#72)
* Nightcrawler - *Enemy*: X-Men defeat Sinister on the space station of the High Evolutionary (X-Men #380)
* Polaris - Lorna becomes leader of his Marauders while possessed (X-Men #219-243)
* Psylocke - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39)
* Quicksilver - *Enemy*: Sinister spies and plots against the new team X-Factor (#72), and they cross paths in X-Cutioner's Song (U X-Men #294-295)
* Rogue - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), later they clash over the fate of Threnody in Los Angeles (X-Men #2.27) and in space (X-Men #380)
* Sabretooth - Sabretooth was employed in Sinister's Marauders (from before X-Men #212 to #243). Nickname: "Little Man" (XM #221)
* Shadowcat - *Enemy*: X-Men defeat Sinister on the space station of the High Evolutionary (X-Men #380)
* Siryn - Sinister has her DNA in his collection (X-Men #2.52)
* Storm - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), later X-Men defeat Sinister on the space station of the High Evolutionary (X-Men #380).Nickname: Wind-rider (#243)
* Strong Guy - *Enemy*: Sinister spies and plots against the new team X-Factor (#72)
* Sub-Mariner - Sinister has his DNA in his collection (X-Men #2.52)
* Valerie Cooper - *Enemy*: Sinister spies and plots against the new team X-Factor (#72), and he holds her ransom in X-Cutioner's Song (X-Force #16)
* Wolfsbane - *Enemy*: Sinister spies and plots against the new team X-Factor (#72)
* Wolverine - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), later X-Men defeat Sinister on the space station of the High Evolutionary (X-Men #380)