Straight from the Heart

To start this quest you must have completed, "Tower of Ethereal Light", "In the Eye of the Mist", "Fang of the Wyvern", "A Cruel Fate" and "Showdown at Sundown". You also need 60 Magic, 75 Extracting, 73 Digging, 65 Divality, 71 Reaping and 59 Mandala Making.

1. Start by talking to the Mayor of Valeska who will explain the Grand Venom Root which harnesses the life essence of all the people of Valeska is being threatened by a mysterious force. A cutscene will play explaining the feud between the Vampites and the resistance. After the cutscene, an alarm will sound and the mayor will grab his gun and ask you to follow him.
2. Follow the mayor outside and you will see 3 Vampite Sorcerers Lv 108, they will glare at you and realize that the Grand Venom Root is right behind you and will attack you. They mostly use melee so using an Ethereal Light Rod with your best Light based spell will dispatch them easily.
3. After the fight, some guards will rush to the mayor and another cutscene will play where a vampite with a blood red trimmed cloak will attack you and the guards. The vampite will then explain that it is the Lord of all Vampites. He will reveal his name is Lord Drexiat and that the Grand Venom Root will be his to control and kill all humans in Valeska and disappear. After he disappears, talk to the mayor and the mayor will reply that you will need a special shield to defend against Drexiat as his claws penetrate any normal shield.
4. You will need to head to the Sun Worshipper that you talked to to start "Showdown at Sundown". When you walk to up to her and she will recognize you and she will ask what the trouble is. Tell her about fighting Lord Drexiat and she will reply you need a Blood Warden Shield in order to block his claws. To get this, you must make a batch of 50 Blood Mandalas, bury the shield in the dirt of Valeska for 2 minutes(Game time) and bless it (requires 65 Divality).
5. After finishing making the Blood Warden Shield, head back to the mayor and tell him that you are ready. As soon as you end the conversation a cutscene will play where a giant Skeletal Dragon Lv 273 will appear and it will attempt to eat the mayor but will be blocked by 3 guards who get eaten up instead. The dragon will exhale a Shadow based breath that hits the 5 squares in front of in a column. To avoid this simply step 2 squares away. Other then this attack, it mostly uses melee so ranged or magic work.
6. When the dragon is completed, pick up it's bones and give it to the mayor. The mayor will then tell you that he can use this to forge a special vampite slaying weapon to give you even more of an edge. Another alarm will sound and an entire horde of vampites will appear and the mayor will tell you that you need to protect him while he makes the weapon. The horde has 5 waves, you will have 30 seconds between each wave to heal or bank (talk to the mayor after the wave and he will give you an instant bank scroll which will let you withdraw or deposit items in the bank).
7. The vampites in the waves are as following:

Wave 1=3 Vampite Knights Lv 85, 2 Vampite Sorcerers Lv 108

Wave 2=5 Vampite Knights Lv 85, 1 Vampite Guardian Lv 151

Wave 3= 2 Vampite Guardians Lv 151, 7 Vampite Rangers Lv 73

Wave 4= 10 Vampite Rangers Lv 73

Wave 5= 5 Vampite Knights Lv 85, 5 Vampite Rangers Lv 73, 1 Vampite Sorcerer Lv 108, 1 Skeletal Dragon Lv 273. If things get too difficult, you can exploit their weakness to Light by using a handful of items made by the Alchemy skill.

1. After finishing the waves, talk to the mayor and he will give you a Bloodbreaker which is a sacred axe that is used to kill off any vampite. Talk to the mayor again and he will inform you that Lord Drexiat is hiding in his throneroom of his castle. To get there you will have to head northeast of Valeska.
2. As soon as you walk towards the entrance, the 2 Vampite Guardians Lv 151 will glare at you and lunge at you. Expose their weakness to Light based damage to end this fight quickly. Shortly after you dispatch them a cutscene will play where Drexiat's maiden will appear and inform you that she doesn't want him alive anymore. Comfort her that you are there to end his life and tell her to head to Valeska and to give the mayor your approval. She will thank you and run off.
3. Now your main goal is to get to throne room, which is barricaded by 3 gates. The First gate being Red, the second one being black and the 3rd one being yellow. You will need to defeat Vampite Sorcerers Lv 108 to obtain the Red key, Vampite Rangers Lv 73 for the Black key and Vampite Knights Lv 85 for the Yellow key. As soon as you get the keys head up to his throne room and use them.
4. If you haven't done so already equip the Bloodbreaker and Blood Warden Shield before you enter. Once you enter a cutscene will play, after the cutscene you will be attacked by Drexiat's pet Cerberus Lv 200. Cerberus will be a tough opponent as each head conveys an attack style. The one on the left will bite you for melee damage, the one in the middle will exhale a breath which will do magical damage and the one on the right will spit fire at you for ranged damage. Each head has 75,000 life points. Focus on the head on the right first as this will make it easier. To avoid the bite attack just move away from the head, you will tell when the left head is about to bite cause it will growl at you. To avoid the breath attack move 2 squares away like you did with the Skeletal Dragons the middle head will start to inhale for it's attack. To avoid the spitfire attack just move on the side of the line of fire you will be able to tell when the ground the head is about to spit turns a greenish yellow color.
5. After defeating Cerberus, Drexiat will get mad and jump off his throne ensuing the fight beginning. He will summon Vampite Knights Lv 85 to aid him when his health is reduced by 25%. Each time will increase the amount by 1. He has 3 main attacks, the first one will be to summon a cloud of bats which will do periodic Blood damage by 10% for each interval of time. This attack isn't the easiest to avoid but it isn't the hardest. The second attack is the hardest to avoid, he will shout "I sacrifice my blood to end you!" he will lose 1/25 of his healthy making things a little easier for you but a bunch of blood pillars will appear on spots on the ground and do 40% of your max hp damage. The way you can indicate where one will appear is if the square is blood red. His easiest attack to avoid is his claw attack which he will slash in a circle around him, just simply move out of the circle (although with the Blood Warden Shield the damage is reduced by 75% making it unnecessary to even dodge.
6. After defeating Drexiat, strike him down with the Bloodbreaker and he will shatter to pieces. Talk to the mayor again and tell him you defeated Drexiat. He will inform you that the city is safe for now and will inform you when new threats are lurking.
7. Quest finished!