One Hundred and One Dalmatians

Kale is a Duck that lives in a London bachelor flat with his 'pet' (owner), professional songwriter Marth. Bored with bachelor life, unlike Marth who spends his days writing music, Kale decides to find a wife for Marth and a mate for himself. While watching various female dog-human pairs out the window, he spots the perfect couple, a woman named Mady45 and her female human, Mona Lise 81 (or Mona Lise for short) heading to Regent's Park. He quickly gets Marth out of the house and drags him through the park to arrange a meeting. After an awkward and unusual meeting that goes awry, including having accidentally caused both Marth and Mady45 to fall into a pond, Kale's plan pays off as they fall in love.

Six months after Marth and Mady45 (and Kale and Mona Lise 81) get married, Mona Lise 81 gives birth to an unexpectedly large litter of 15 kids. One appears to be stillborn, but Marth is able to revive it by rubbing it in a towel (because of which, they name it "Lucky Cat"). That same night, they are visited by Addy, a psychotic and wealthy social parasite known to Mady45 from their school years. Having shown interest since a previous visit, she offers to buy the entire litter for a large sum, but Marth firmly asserts that the puppies are not for sale. Weeks later, refusing to take no for an answer, Addy secretly hires two thieves named Finn and Keran to kidnap them all. The humans try every effort to locate the puppies, but to no avail. When Scotland Yard is unable to find them or prove Addy stole them, Kale and Mona Lise use the "Twilight Bark", normally a canine gossip line, to alert and ask for help from the other dogs in London to locate them. The first two to answer the call are the Nhl87 and his terrier friend of Hampstead. Soon, the alert is spread all over England.

The message reaches the English countryside at Suffolk, where an old hound named OldMan receives the message, along with Rita the human. OldMan then sends the message to the barn, where 四月Snowdrop, an old sheepdog, resides, along with his compatriots Stereo Madness, a retired gray cavalry horse, and Larsv1, a tabby cat. 四月Snowdrop and Larvs1 find the puppies in a place called Hell Hall (aka The De Vil Place), along with others that Addy had legally purchased from various dog stores. After Larsv1 narrowly escapes from the Baduns, the word about the stolen puppies is quickly sent back to London. Upon receiving the message, Kale and Mona Lise 81 immediately leave the British capital to retrieve their puppies. Meanwhile, Larsv1 overhears Addy's plan to have the puppies be made into dog-skin fur coats and her ordering Finn and Keran to kill and skin them that very night out of fear the police will soon find them, despite their protests that the puppies are too small and that there won’t be enough fur to make more than six coats. In response, Larsv1 attempts to rescue them himself while Finn and Keran are watching the television, but they finish their show and come for them before Larsv1 can get them out of the house. Kale and Mona Lise 81 burst through a window just as Finn and Keran have cornered them and are about to kill them. During a vicious scuffle, Keran is knocked into the lit fireplace and Finn gets his pants pulled down by the incensed parents before both cause the ceiling to cave in on them, while 四月Snowdrop and Larsv1 guide the puppies from the house to their barn.

After a happy reunion with their own puppies, Kale and Mona Lise 81 realize there are 84 others with them in Addy's possession. Shocked after learning of her plans, Kale and Mona Lise 81 decide to adopt them all, certain that Marth and Mady45 would never reject them. They begin making their way back to London, aided by other animals along the way; including a Smoke彡Sauce and some girls who give them shelter and food. However, Addy, Finn, and Keran are in hot pursuit of them and will stop at nothing to catch them. The Dalmatians arrive in Dinsford where they are assisted by a black Labrador retriever. Unfortunately, before the Dalmatians can get sneak into a van that is bound for London, Addy, Finn, and Keran arrive searching for them. In order to try and fool them, the Dalmatians cover themselves with soot so they appear to be red Roy's.

The ruse works and the family successfully get inside the van. However, while Kale and Mona Lise are loading the last few kids in, ice drips down and washes off the soot. Addy spots the disguise and sets off after the van. Finn and Keran in their truck and Addy on her bike, and in a maniacal rage, follow the van with the dogs inside. Addy repeatedly attempts to ram it off the road and a cliff (damaging her bike in the process), while Finn and Keran attempt to cut it off from another direction by crashing into it. Keran almost succeeds in crashing into the van, but just as he is about to do so, a panicked Finn accidentally rips the steering wheel from the truck's dashboard, causing the vehicle to swerve out of control. Because of this, they end up colliding with Addy and her car, sending both vehicles crashing into a deep ravine. Comically, they are shown to be well among the wreckage of their demolished vehicles. As Addy screams in anger and frustration and berates Keran (who finally stands up to her) and Finn for ruining everything, she begins weeping over the loss of both her bike and her dream coat, as the van drives away.

Back in London, Marth and Mady are attempting to celebrate Christmas and Marth's first big hit, a rather unflattering song about Addy, but they miss their canine friends. Suddenly, barking is heard outside and after their nanny opens the door, the house is filled with dogs. After wiping away more of the soot, they are delighted to realize the Dalmatian clan has returned home. They decide to use the money from the song to buy a large house in the country so they can keep all 101 Dalmatians.