recursal/Fanatic-Fandom huggingface dataset:
Gello

**Gello** is an unlockable activated item added in *The Binding of Isaac: Repentance*.

## Effects

* Spawns a demon familiar that's attached to Isaac, moving in the direction Isaac shoots, and automatically shooting (whenever Isaac is shooting) in the direction of the closest enemy to it, using Isaac's damage, tears, range, shot speed, and special tear effects.
	+ The item is initially held over Isaac's head until he fires, which launches the familiar, dealing 3x Isaac's damage.
	+ If Isaac has any tear modifier that requires him to charge his shots (like ), Gello will automatically "release" the fire button for himself every time he is fully charged. If Isaac releases the charge button himself, Gello will do that too, regardless of his current charge of an attack.
	+ Gello's tears deal 0.75x Isaac's damage, or 1.0x if used by  Lilith or  Tainted Lilith.

## Notes

* Tainted Lilith attacks in a way nearly identical to this item, except she can recall it and launch it again.
* If used multiple times in the same room, the Gellos will eventually overlap perfectly and appear as one after some movement, but all remain functional. This makes Gello exceptionally powerful in Greed Mode, Boss Rush, and against The Beast.

## Synergies

* : Spawns a red wisp on the middle ring. The wisps will orbit Gello instead of Isaac while it's active.
* Tainted Azazel: Each time Gello starts charging an attack, he will "sneeze" just like Tainted Azazel does, cursing enemies in front of him. This allows Tainted Azazel to keep enemies cursed without needing to come up to a dangerously close distance to them.

* Tainted Lazarus: The familiar persists when switching states.

* : When the baby is launched, any enemies it kills in its trajectory will freeze and any frozen enemies the baby is launched into slide if Isaac is moving, similarly to when kicked by Isaac.

## Trivia

* Gello is a revenant in Greek mythology who causes infertility, miscarriages, and infant mortality.
* It is implied to be a fetal .
Heartbreak

**Heartbreak** is an unlockable passive item added in *The Binding of Isaac: Repentance*.

## Effects

* Grants +0.25 damage for every broken heart Isaac has.
* Immediately grants 3 broken hearts.
	+ Every otherwise fatal hit will add 2 more, replacing other types of hearts if necessary, and deal 40 damage to all enemies in the room.
	+ Once Isaac has no non-broken hearts left, he dies. Extra lives will apply at this point.
	+ The effect does not save Isaac from fatal Devil deals.
		- However, by placing a bomb, taking an otherwise lethal Devil deal, then dying from said bomb during the pickup animation, the Devil item can be taken at the cost of some broken hearts.

## Interactions

* : Heartbreak does not protect Isaac from Damocles.
* : The ghost gains 2 extra hits per floor, and every hit they take will damage all enemies in a room as well.
* : Guppy's collar has a chance to respawn Isaac with an extra half soul heart on death, even if Isaac has already reached 12 broken hearts.
* Keeper: Keeper will gain 1 broken heart instead of 3. Taking fatal damage will only grant Keeper 1 broken heart.
* / : Heartbreak does not protect Isaac from these effects.
* Tainted Keeper: Tainted Keeper will gain 1 broken heart instead of 3. Taking any damage will kill him.
* The Lost /  Tainted Lost: The Lost has full benefit of the item. This lets him survive 4 extra hits, each hit adding 1 damage, and the 5th is fatal.
	+ **The Lost** / **Tainted Lost** +  / : No broken hearts are added by the item/card, thus having no effect on Heartbreak.
* Tainted Eden: The starting broken hearts are removed when Heartbreak is rerolled; however, any broken hearts gained from lethal damage will persist.
* Tainted Isaac: The starting broken hearts are removed when Heartbreak is dropped; however, any broken hearts gained from lethal damage will persist.
* Tainted Jacob: This effect will save Tainted Jacob while he is in his Lost form, adding two broken hearts to his regular health.
Golden Razor

**Golden Razor** is an unlockable activated item added in *The Binding of Isaac: Repentance*.

## Effects

* Grants 5 Pennies on first pickup.
* When used, consumes 5 Pennies and grants +1.2 damage for the rest of the room.
	+ The effect can be stacked.
	+ If Isaac has fewer than 5 coins, nothing happens.

## Notes

* Using the item will give Isaac's tears a golden tint that becomes more noticeable with each use, up to a maximum of three times. This effect is purely cosmetic.
* When unlocking the item, coins do not actually have to be spent, just removed. Actions such as donating to a Donation Machine or items like  will also count as long as the coin amount goes from 99 to 0.

## Synergies

* +  as  Judas /  Dark Judas: Also invokes the effect of  when used, which occurs after the damage increase and deals an additional +5 damage; non-boss enemies killed by this effect also have a chance to drop 1-2 pennies.
* : Spawns yellow wisps on the middle ring, looking like coins. Wisps' tears have a 15% chance of inflicting  effect on enemies.
* : The increased money capacity can allow the Golden Razor to be used more than 10 times as much before the player runs out of money.
* : The damage bonus from each use will be permanently locked at the highest achieved value in a single room.

## Trivia

* This item is similar to , the only difference being the cost in coins instead of hearts.
* The item is based on the Golden Razor Blade from *The Binding of Isaac: Four Souls* card game.
Gurglings

This article is about the boss. For the enemy, see Gurgling (Enemy).

Double Trouble

(with another pair of Gurglings, Turdlings, or  C.H.A.D.)

(with Chub, The Stain, or Gurdy)

(with Gurdy and Gurdy Jr.)
Degraded Boss

**Gurglings** are a boss that can appear:

* Only in the Basement.
* In the Basement and the Burning Basement.

They each have  90 HP /  60 HP.

## Behavior

The Gurglings spawn as a pair and wander around the room. Each individual Gurgling has one attack in total which is performed independently of the other:

* Rushes towards the player when aligned in any cardinal direction, leaving behind damaging Red Creep until she has run into a wall.
	+ After rushing into a wall, she pauses for a brief moment, and then spawns 0-2 Attack Flies.
	+ Her dash can be interrupted if she runs into an Attack Fly.

## Champion Versions

 **Black**: Gurglings spawn Troll Bombs at regular intervals instead of Red Creep when rushing towards the player. They take only 5 damage from their own bombs. They don't spawn any Attack Flies.
* While petrified, the Gurglings take full damage from own bombs.

 **Yellow**: Three Gurglings will appear instead of two. They are faster but do not leave any Creep. They don't spawn any Attack Flies.
## Gallery

* A Gurgling in-game.
* A Black Champion Gurgling.
* A Yellow Champion Gurgling.
* A Gurgling as one of Delirium's forms before Repentance.

## Arena

Gurglings can spawn in normal or tiny rooms.
When fighting Gurglings, the following obstacles can spawn:

* Nothing
* 2 rocks (1 in top-right and 1 in bottom-left corners)
* 2 urns (1 near top-left and 1 near bottom-right corners)
* 7 Red Poops & 6 pits in the bottom of the room
* 4 Red Poops (2 in top-right and 2 in bottom-left corners, covered with 3 rocks and 1 metal block each)

In tiny rooms, one Gurgling will appear behind pits.

* Tiny boss rooms no longer appear.

## Trivia

* Gurglings appear to be the first stage of the "Gurdy" boss line, with the second stage as Gurdy Jr., third as Gurdy, and final as Mama Gurdy.
* The Gurglings and  their poop-themed variant, the Turdlings, spawn in groups of three during the Boss Rush.
* If the Gurglings audio is slowed down or if one spawns with the gigantic modifier, the audio reveals that it is a little kid saying "Rawr!"
* Unlike the regular Gurgling, boss Gurglings have a one-second death animation.
Guardian Angel

**Guardian Angel** is an unlockable passive item.

## Effects

* Spawns an orbital familiar that blocks enemy shots and deals 7 damage per tick or  105 /  52.5 damage per second on contact.
* Increases the speed of all orbital familiars.
* This item belongs to the Seraphim set. Collecting three items from this set will transform Isaac into an angel.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into a three-faced version of himself.

## Notes

* The increased orbital speed improves odds of being protected from enemy shots.

## Synergies

* : This familiar will also reward 2 Black Hearts when sacrificed.
* : The orbital speed boost from Guardian Angel can be combined with that of Spin to Win, causing all the orbital familiars to spin extremely fast around Isaac.

## Interactions

* : Guardian Angel counteracts most of the slower orbiting speed.

## Trivia

* A guardian angel is a type of angel that is assigned to guide or protect a particular person/group.
Homunculus

### Found In

**Homunculi** attempt to chase Isaac but have a limited range of movement due to spawning attached to a wall or an  Obstacle. Given enough time it will detach, spawning a small pool of Red Creep and shooting 6 projectiles in all directions and chasing quickly after Isaac. It also leaves a small pool of Red Creep upon death.

Destroying the obstacle that a Homunculus is attached to will prematurely release it.

#### Notes

* The Homunculi encountered in the Mr. Fred boss fight can only detach under Mr. Fred's command, not at free will. If there are any remaining Homunculi after Mr. Fred is killed they will remain permanently attached.

## Variations

### Stage HP

 60
 0

### Found In

Spawned by  Sisters Vis

**Begottens** behave like Homunculi but do not spawn any Red Creep. When it detaches from the wall or  Obstacle, it fires 6 blood shots in all directions, turns the room dark and becomes invisible. Attacking it causes it to temporarily become visible.

### Notes

* They can spawn in unique Devil Room layouts if Isaac is holding the .

## Gallery

* Unused pre-release sprite of Begotten found among the Room Editor files.

## Trivia

* A homunculus is a very small human or humanoid creature.
	+ In medieval art, the infant Jesus Christ was often portrayed as a homunculus, with a man's face on a baby's body, to signify being perfectly formed at birth.
* Similar to Frowning Gapers and Nulls, Homunculi and Begottens are seen in a sleep-like state at the start of a room before they immediately open their eyes and attempt to pursue the player.
* Begottens are the only non-boss enemies that can cast a "curse of darkness" effect.
* Homunculi will still leave behind creep if re-rolled with .

## References

1. ↑ https://factsandhistory.com/why-do-babies-in-medieval-art-look-like-creepy-adults/
Gurgling (Enemy)

This article is about the enemy. For the boss, see Gurglings.

### Found In

**Gurglings** are ordinary enemies that behave slightly differently from their boss counterparts. They have significantly less HP, leave a constant trail of Red Creep, and after dashing, shoot out six blood projectiles instead of spawning Attack Flies.

## Gallery

* Unused pre-release sprite of a Gurgling found among the Room Editor files.

## Trivia

* Gurglings appear to be the first stage of the "Gurdy" boss line, with the second stage as Gurdy Jr., third as Gurdy, and final as Mama Gurdy.
* If the Gurglings audio is slowed down or if one spawns with the gigantic modifier, the audio reveals that it is a little kid saying "Rawr!"
Guppy's Hair Ball

**Guppy's Hair Ball** is an unlockable passive item.

## Effects

* Spawns a hairball familiar that loosely follows behind Isaac, blocks shots, and can be swung like a flail to damage enemies.
	+ The ball deals 5 damage per tick, but grows, increasing damage by 2 each time it kills an enemy — up to 5 times for a maximum of 13 damage. The damage it deals per tick (each half-second) is `(level × 2) + 3`.
	+ The hairball level decreases upon entering a new floor: if level 2, it reverts to level 1. If level 3 or 4, it reverts to level 2. If level 5, it reverts to level 3.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into Guppy.

## Notes

* The hairball's hitbox is the same size regardless of level.
* If Isaac has transformed into , Guppy's Hair Ball spawns Blue Flies when it deals damage.
* If Blindfolded, the ball occasionally spawns a Blue Fly while it's damaging an enemy.

## Trivia

* This item is used in Cat Got Your Tongue (challenge #8).
* The function and flavor text of this item might reference the idioms "no room to swing a cat" and "can't swing a dead cat without hitting...".
* In the original *The Binding of Isaac*, Guppy's Hairball did not count towards the Guppy transformation.
Globin

### Found In

**Globins** chase after Isaac, similar to Gapers but are much faster. Instead of dying, they will collapse into goo and then regenerate after a few moments unless destroyed in their goo form. Each time a Globin is turned into goo form, it will have its total health decreased. Globins will do 1 full heart of damage on contact.

## Variations

### Stage HP

 33
 0

### Found In

Chance to replace Globins

**Gazing Globins** are an alternate version of the Globin which can sometimes replace regular Globins. Gazing Globins run towards Isaac with increased speed and slide away when they collapse into goo, but otherwise function identically to regular Globins.

### Stage HP

 33
 0

### Found In

Chance to replace Globins and Gazing Globins in the Dank Depths

**Dank Globins** behave identically to regular Globins. Each time they collapse, they leave behind a puddle of slowing Black Creep and spawn a Spider. They spawn another puddle of Black Creep when finished off.

### Stage HP

 33
 0

### Found In

**Cursed Globins** are a variant of Globin that chase Isaac at a pace similar to a Gazing Globin. However, they will split into two piles of goo instead of one, and unless killed in this goo form, they will regenerate quickly into two Cursed Globins.

There is a maximum number of times the Cursed Globin can split.

Champion Cursed Globins will split into non-champion enemies.

### Stage HP

 33
 0

### Found In

**Black Globins** walk towards Isaac, launching Spiders towards Isaac every time it takes damage. Upon death, they spawn another spider and split into a Black Globin's Head and a Black Globin's Body. This makes them the only Globin variant that doesn't have a goo form.

### Stage HP

 20
 3

### Found In

**Clickety Clacks** are a bony version of Globins that alternate between chasing Isaac and wandering around the room. They turn into a pile of bones that can block Isaac's tears when killed, and will eventually regenerate if any other Clickety Clacks in the room are still alive. Only when all Clickety Clacks in the room are dead will the piles of bone disappear.

## Gallery

* A Cursed Globin's appearance in Gehenna.

## Notes

* Dark Red Champion Globins will turn into goo twice.
* To prevent softlocks, Clickety Clacks cannot spawn as White Champions.
* 3 Clickety Clacks spawn at the beginning of the Clutch boss fight

## Trivia

* Sloth is a recolored Globin.
* Super Sloth is a recolored Gazing Globin with a large head.
* The name of the monster is a type of protein and is also similar to a goblin.
* Globins appear to be based on the Red Skeletons from the *Castlevania* series since they reform from their pile of bones after being killed. They can only be killed using a special weapon or spell.
* Clickety Clacks seem to be based on Dry Bones, a *Mario* enemy that has a similar mechanic.
* The Cursed Globins first appeared in the *Antibirth* mod where they regenerated at a slower rate.
* Cursed Globins act similarly to Cursed Crystal Spiders from *Nuclear Throne*.
Jar of Wisps

**Jar of Wisps** is an unlockable activated item added in *The Binding of Isaac: Repentance*.

## Effects

* Spawns a wisp that orbits Isaac, fires tears, blocks enemy shots, and deals contact damage to enemies, much like the ones spawned by .
	+ The jar initially spawns only one wisp, but spawns an additional wisp each time the jar is used, up to a maximum of 12 per use. The number of wisps that will be spawned by the jar is indicated by both a counter and the jar visually filling up with wisps.
	+ The wisps spawned by the jar can be ones created by any Book of Virtues synergy, although basic wisps are much more common than special variants.
* Isaac can have up to 3 rings of wisps; an inner, counter-clockwise spinning ring of 6 wisps, a center, clockwise-spinning ring of 8 wisps, and an outer, counter-clockwise spinning ring of 12 wisps, for a total of 26.

## Synergies

* +  as  Judas /  Dark Judas: Will only spawn  wisps that increase Judas' Devil Room chance by 10% for each one he has.
* : Triples the wisps which are spawned including any special wisps spawned.
* : The number of wisps spawned is doubled.
	+ **Car Battery** + : The number of wisps spawned is multiplied by 6.

## Notes

* While most wisps that can be given act similarly to normal wisps, there are some with effects that can potentially harm Isaac.
	+ Wisps look like bombs and spawn Troll Bombs when destroyed.
		- wisps look like gold tinted bombs, and will spawn Golden Troll Bombs.
		- Bomb wisps with a gray tint are not dangerous;  wisps only invoke their special effect when said item is used.
	+ Wisps that look like gray cubes will invoke the effect of the  when they take damage.
	+ / Wisps fade into and out of existence and have a chance to teleport non-boss enemies to a random spot in the current room when their tears hit them.
* Switching the jar with other active items and then picking it up again does not reset the number of wisps that will be spawned on use.

## Trivia

* This item functions similarly to  and .
Guts

### Found In

**Guts** is a monster that attaches itself to a wall or obstacle, such as a rock, rolling around the contour of the terrain.
If the obstacle it is attached to is destroyed, then it will continue rolling in the direction it was previously traveling until it meets another wall or obstacle.

They make up for their limited movement by being very fast, and in numbers they can tighten movement space (especially in layouts containing narrow passages). Two of them are spawned by Mama Guts upon death.

## Variations

### Stage HP

 28
 0

### Found In

Chance to replace Guts in the Scarred Womb

**Scarred Guts** are paler versions of the regular Guts. They have a chance of replacing normal Guts in the Scarred Womb. They behave identically to regular Guts but leave behind a trail of damaging Red Creep and move slightly faster than their regular counterparts.

### Stage HP

 28
 0

### Found In

**Slogs** roll around, while leaving a trail of slowing Black Creep. However, when Isaac is in their line of sight, they charge at him. While Guts and Scarred Guts rotate counter-clockwise, Slogs rotate clockwise.

### Stage HP

 25
 0

### Found In

**Cysts** behave like normal Guts but they will occasionally shoot 1 blood shot towards Isaac if he is close enough.

Two of them will be spawned if a Dead Meat is killed.

## Notes

* Guts and their variants are immune to 's effect.

## Trivia

* The Cyst first appeared in the *Antibirth* mod.
* Cysts in real life are abnormal growths, usually non-cancerous, filled with fluid or other semi-solid substances. Some even develop in organs or contain pores.
Gyro

### Found In

**Gyros** were introduced in *The Binding of Isaac: Repentance*. They look like a piece of meat with a bone right through the middle.

They move themselves by rolling — similar to how a wheel moves. When Isaac is in their line of sight, they will charge at him quickly and can rotate to continue pursuing him for a short time. Afterward, the Gyro will briefly quit chasing Isaac and slowly roll around as if in exhaustion before resuming its normal behavior. Gyros will convert into Grilled Gyros, if in contact with fire.

## Variations

### Stage HP

 20
 0

### Found In

**Grilled Gyros** function relatively the same to normal Gyros, but they move at a faster pace and leave some damaging flames in its trail, but only when chasing Isaac.

## Trivia

* Both Gyro variants first appeared in the *Antibirth* mod.
* Edmund has expressed that this enemy doesn't fit in the game because it does not have a face like the other enemies.
Gurdy Jr.

Double Trouble

Degraded Boss

**Gurdy Jr.** is a boss that can appear in all environments of Chapter 2 (Caves, Catacombs, Flooded Caves).

## Behavior

### Phase 1

* Spawns a Pooter.
* Jumps and shoots a radial of 8 tears in all directions on landing.
* Charges towards Isaac at high speeds, sliding while bouncing off obstacles and walls, She gradually loses speed before coming to a full stop.
	+ Any Pooters caught in her charge will be killed.
	+ The course of her charge can be affected by Tear knockback
	+ If Gurdy Jr. charges into an active bomb, she is slowed down tremendously.

### Phase 2

* When she has less than 50% health, she uses her charge attack continuously.

## Champion Versions

**Blue**: Instead of one Gurdy Jr., there will be two 42% smaller ones. This version has 45% less HP than the original (137.5) and only uses the charging attack. It drops a Soul Heart upon death.
**Yellow**: 15% larger than the regular, with 25% more HP (312.5). She spawns Super Pooters instead of regular Pooters. Does not shoot projectiles of any sort.
## Gallery

* Gurdy Jr. in-game.
* Blue Champion Gurdy Jr.
* Yellow Champion Gurdy Jr before.
* Gurdy Jr. as one of Delirium's forms.

## Notes

* Slowing Gurdy Jr. will, for the most part, render her charge attack useless.
* Piercing tears lack knockback and cannot be used to divert or stop Gurdy Jr.'s charge attack.
* If Gurdy Jr. is feared/stunned during her charge attack after the effect wears off, she will immediately charge at Isaac.
* Gurdy Jr's charge attack has no telegraphing, making it very dangerous to stay close due to the lack of a warning.

## Trivia

* Gurdy Jr. was added in the *Wrath of The Lamb* DLC for the original *The Binding of Isaac*.
	+ Gurdy Jr. from *Wrath of the Lamb* is larger than Gurdy Jr. in Rebirth.
	+ In the original game, Gurdy Jr. could be encountered in the Cellar.
* Gurdy Jr. appears to be the second stage of the "Gurdy" boss line, with the first stage as Gurglings, third as Gurdy, and final as Mama Gurdy.
* Gurdy Jr. is female. [*citation needed*]
* Edmund McMillen has referred to the double Gurdy Jr. champion room in an interview as "double Gurditration".
Guppy's Head

**Guppy's Head** is an activated item.

## Effects

* Spawns 2-4 friendly Blue Flies.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into Guppy.

## Synergies

* : Summons wisps in the outer ring instead of flies. Wisps summon Blue Flies when destroyed. One wisp contains one Blue Fly.
* : Increases range of flies spawned to 4-8.
* : Doubles flies spawned.
* 9 Volt: Guppy's Head slowly gains charge while in a hostile room.

## Trivia

* This item is used in Cat Got Your Tongue (challenge #8).
* The item is a reference to Edmund McMillen's cat also named Guppy.
* is essentially the spider equivalent to Guppy's Head.

## Gallery

* 3DS The icon of Guppy's Head as seen on the lower 3DS screen.
IBS

**IBS** is an unlockable passive item added in *The Binding of Isaac: Repentance*.

## Effects

After dealing enough damage to an enemy, Isaac begins to flash red. Releasing the fire button gives the effect of one of  Tainted ???'s unique poops.

### Throwable

Holds up one of the following types of poop, which he can throw with the fire buttons. All thrown poops deal 15 damage to enemies they hit when thrown (up to 3 times in the case of stone poop).

### Non-Throwable

 Black Poop: the creep also slows enemies and gives Tainted ??? slowing tears.
 Toxic cloud from Stinky poop: the creep poisons enemies and gives Tainted ??? poison tears.
 Flaming Poop: the creep burns enemies and gives Tainted ??? .
 White Poop & its Aura: the creep grants homing and triples Tainted ???'s fire rate and damage.
 Stone Poop: the creep will keep all the extra effects of other poops, even if they are destroyed.

## Notes

* The chance for IBS to activate is dependent on the damage Isaac deals to enemies; the more damage an attack deals, the more likely it is to activate IBS.
* If IBS triggers while Isaac is charging a shot (with items such as , , , etc.), the charged shot will only fire after IBS's effect activates. In the case of thrown poops, the charged shot only fires after Isaac throws the poop IBS gives him.
* Poops spawned by IBS can give pickups.
* If Isaac is currently holding a poop, IBS cannot activate until he throws it.
* Isaac can carry poop he is holding between rooms.
* If Isaac takes damage while holding a poop/bomb, he will drop it where he is standing.
* If Isaac hits an enemy with a thrown poop, it will immediately break.

## Trivia

* IBS stands for Irritable Bowel Syndrome.
* This item was added after Edmund stated on Twitter that Isaac has IBS.
Holy Water

**Holy Water** is a passive item.

## Effect

* Spawns a familiar that follows Isaac. If Isaac takes damage, it will shatter and create a pool of damaging blue creep, similar to .
	+ The pool lasts for ~9 seconds and deals 8 damage per tick to non-flying enemies (24 damage per second).
	+ After breaking, Holy Water will reappear in the next room.
* Spawns a familiar that follows Isaac and launches itself in the direction Isaac shoots. Upon hitting an enemy, it will deal 7 damage and shatter, creating a pool of damaging blue creep that also petrifies enemies that touch it.
	+ Once the pool disappears completely, Holy Water will respawn and can be fired again. Holy Water does not immediately respawn upon entering a new room.

## Notes

* Familiars that follow behind Isaac have a certain priority in how close their position is to him over other familiars, with Holy Water having 5th priority.

## Interactions

* : Familiar is bigger but no effect on damage.
	+ Doubles the initial damage and causes it to also spawn a blue flame on point of impact that blocks shots and deals 6 contact damage per tick to enemies (36 damage per second). The fire can hit flying enemies, persists for the same amount of time as the creep, and cannot be destroyed.
* : Upon killing an enemy while they are inside the puddle of holy water, The enemy bursts into a cluster of petrifying tears.

## Trivia

* The item is a reference to the sub-weapon of the same name from the Castlevania series of games.
* In the original *The Binding of Isaac,* holding Holy Water will turn one of your shooting familiars into , and it will change back when the Holy Water breaks. It will turn back into Brother Bobby after entering the next room.
* The in-game description for Holy Water in the original game was 'Don't Spill It'.
Halo of Flies

**Halo of Flies** is a passive item.

## Effects

* Spawns two Pretty Flies that block enemy shots.
	+ Pretty flies kill some fly enemies upon contact.
	+ The orbital limit of three flies cannot be surpassed with this item, reducing its effectiveness if Isaac has two or more orbitals.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into a giant humanoid fly.

## Notes

* Orbital flies can also be obtained by other means, such as Slot Machines and Pretty Fly pills.
* The following types of flies are instantly killed when they come in contact with the orbitals:
	+ Army Fly
	+ Attack Fly
	+ Dart Fly
	+ Fly
	+ Hush Fly
	+ Moter
	+ Pooter
	+ Ring Fly
	+ Super Pooter
	+ Swarm
* Having multiple copies of Halo of Flies, (such as by ) does not increase the fly cap of 3, unlike .

## Synergies

* : When Isaac uses Abyss to absorb Halo of Flies two gray locusts are created dealing half of Isaac’s damage per tick each.

## Trivia

* This item is used in Solar System (challenge #6).
* This item is a reference to Halo of Flies, by Alice Cooper.
* Halo of Flies was the first orbital item that Edmund McMillen ever implemented into The Binding of Isaac.
* Halo of Flies shares its name with a level from Edmund's previous game Super Meat Boy.

## References

1. ↑ Isaac lore stream https://youtu.be/kby0rXT7qYQ?t=1454
Immaculate Heart

*For the other Angel item with a similar name, see Sacred Heart.*

**Immaculate Heart** is a passive item added in *The Binding of Isaac: Repentance*.

## Effects

* Isaac will frequently fire extra spectral tears that orbit around him until they hit the ground, similar to . These tears mimic Isaac's in most cases.
* x1.2 damage multiplier. This multiplier does not stack with multiple Immaculate Hearts.
* Adds one Red Heart Container and fully replenishes Isaac's health.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into an angel.

## Synergies

* : The extra tears share the same orbit as Angelic Prism, making them very easy to split.
* : Some of the orbiting tears will gain Chemical Peel's 2 flat damage bonus.
* : Death's Touch tear modification will also affect the orbiting tears.
* : Orbiting tears get piercing and homing on nearby enemies on contact, and return orbiting after no targets left.
* : The orbiting tears will be affected by Haemolacria but the tears created upon hit will not orbit.
* : Lachryphagy will affect the orbiting tears and become bigger when in contact with other tears. The Lachryphagy tears will split upon hit and the split shots will orbit around the point where the original tear had split.
* : Isaac will frequently shoot tears that orbit around him, even without pressing any fire buttons.
* : Fires a large number of extra tears alongside the burst that begin orbiting Isaac once they reach the orbit range.
* : Each individual flame shot from the Urn has a chance to spawn an orbiting tear.

## Interactions

* : Tears will orbit very close and fast around Isaac's body, and return to normal orbit once he stops firing.
* /  /  /  /  /  / : No unique interactions; regular tears are generated which orbit Isaac normally.
* : The orbiting tears will not scale with the charge of the tears.
* //: Orbiting tears that stick to an enemy will return to the ring if the enemy cannot be stuck to anymore before the tear's duration ends.
* : Orbiting tears cannot be controlled.
* : The damage multiplier does not stack with that from a white poop.
* : The orbiting tears will orbit whoever fired it, whether it be Isaac or the Incubus.
* : Orbiting tears explode.
* Tainted Bethany: On pickup, grants 12 blood charges.
* : The laser does not contribute in generating orbiting tears.

## Trivia

* Immaculate Heart is from the *Antibirth* mod.
Goat Head

**Goat Head** is a passive item.

## Effects

* A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Chapter 4.
* The spawned door will not disappear when leaving and re-entering the boss room.

## Notes

* The precise effect involves setting the Devil Room chance to 100%, regardless of other effects.
	+ Even if taken after a boss is killed, Goat Head will force a Devil / Angel Room door to spawn on that floor.
* Accepting a deal with the Devil will prevent any Angel Rooms from appearing, meaning that Isaac needs to acquire the Goat Head in a Curse Room,  Locked Chest,  Red Chest, from The Fallen or with , which would allow Angel Rooms to open.
* Goat Head will not force a Devil / Angel Room door to open if the boss fight was in a narrow room.
* Goat Head has no effect in Greed mode and is not normally available.
	+ It can still be a starting item for  Eden, a bonus item from , and is obtainable with  and .
* By touching the white fire in Downpour II and Dross II, Isaac will temporarily become  The Lost. After defeating the boss, Goat Head will always keep the devil deal door open, allowing the Lost to take one Devil Deal item for free.

## Synergies

* : Grants a damage boost
* : Both Angel and Devil Room doors spawn after every boss, and the selected door will never disappear.

## Interactions

* : Overrides Goat Head.
* Tainted Lazarus: The door will only be guaranteed to spawn when the character holding Goat Head enters the room. If the door doesn't spawn after fighting the boss, reentering the room as the correct character will still spawn the door. Once the door spawns, it will never disappear.

## Trivia

* This item is a reference to how goats and their blood were often used as a common sacrifice proxy. This is even more evident by the pickup quote.
* This item actually sets devil deal chance to 6660% under the hood, but the value is truncated in the HUD.
God's Flesh

### Collection Grid

*(page 4, column 13, row 2)**(page 4, column 13, row 2)**(page 4, column 14, row 2)*

**God's Flesh** is a passive item added in *The Binding of Isaac: Afterbirth*.

## Effects

* Tears now have a 10% chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac.
	+ Shrunk enemies can be crushed and killed by walking over them.
* The shrinking effect lasts 5 seconds.
* This item belongs to the  set. Collecting three items from this set will transform Isaac into a walking mushroom.

## Notes

* The shrinking effect does not affect bosses or mini-bosses.
* Any enemies that are spawned from the death of a shrunken enemy do not carry over the shrunken effect.
* Champions and enemies that explode upon death will damage Isaac if crushed.
* Shrinking the heart of a Mask + Heart will cause its corresponding Mask to shrink as well. The Mask can be crushed and killed separately.
* The chance to fire a shrinking tear does not scale with Luck.

## Synergies

* : If an angry Blood Puppy is shot with a God's Flesh tear, Isaac can instantly change it back to a tamed Blood Puppy by touching it.
* /  / : Split tears will retain shrinking effect if main tear had shrinking effect. With Compound Fracture and The Parasite, tears with a shrinking effect look like normal tears.
* : Finger can also apply the shrinking effect.
* : Will occasionally fire tears with shrinking effect. All burst tears have a chance to apply the shrinking effect.
* : Tear flickers blue, capable of shrinking enemies when it does.
* : Electricity connected to tears with shrinking effect has a chance to shrink enemies.

## Interactions

* : Only main tear has a chance to apply a shrinking effect.
* / Azazel: Brimstone shot becomes blue.

## Trivia

* The term *God's flesh* is a nickname for psychedelic mushrooms.
* In Aztec culture, hallucinogenic mushrooms were eaten during religious ceremonies. The Aztec name for these mushrooms translates to "god's flesh".
* It may also be a reference to Industrial/Experimental Metal band Godflesh.
* Using God's Flesh on a Rag Man head will shrink it and reveal that there is a very small, nearly invisible body underneath.
* The effects of this item are similar to the Shrinker from Duke Nukem 3D, including the ability to kill shrunken enemies by stepping on them.
* God's Flesh can shrink the skull that The Siren leaves behind on death. It can still be destroyed by walking over it, and will pull from the usual skull drop table.
Ghost Bombs

**Ghost Bombs** is an unlockable passive item added in *The Binding of Isaac: Repentance*.

## Effects

* Gives Isaac 5 Bombs.
* Isaac's bombs create ghosts when they explode, which rapidly chase and deal contact damage to enemies.
	+ The ghost deals contact damage equal to half of Isaac's damage per tick (2x Isaac's damage per second).
* After 10 seconds, the ghost explodes, dealing 7 damage to nearby enemies up to 3 times and destroying nearby projectiles. Isaac does not take damage from the explosion.
	+ If there are no enemies in the room, the ghost follows Isaac. However, it cannot follow Isaac between rooms.

## Notes

* Friendly enemies can be killed by the ghosts.

## Synergies

* : Has a chance to shoot a Ghost Bomb that also has spectral properties and can travel through objects.
* : Split bombs create ghosts that instantly launch themselves at enemies and explode, similar to . They each deal 2x Isaac's damage, up to 4 times.
* : Ghosts appear larger and do extra damage only upon exploding.

## Trivia

* Defeating Delirium as most tainted characters will unlock their gameplay characteristic. Interestingly, Tainted Lost's passive ability to reroll low quality items () is unlocked through defeating The Beast instead.
* This item may be a reference to "Super Ghost Kamikaze Attack" from *Dragon Ball Z*.
Guppy

After picking up 3 items from the following list Isaac turns into his cat **Guppy**.

 As Guppy, Isaac gains flight, and when one of his tears or one of his familiar's tears hit an enemy, a Blue Fly spawns.

 As Guppy, Isaac gains flight, and when one of his tears hit an enemy, there is a 50% chance to spawn a Blue Fly.

## Notes

* spawns flies only very rarely.
* If all the 9 extra lives have been consumed,  is removed from Isaac's inventory. This causes the transformation to be removed.
* Duplicated Guppy items count towards the transformation.

## Unlockable Achievements

* Guppy's Hairball - Become **Guppy**.

* Cat Got Your Tongue - Become **Guppy**.

## Trivia

* This transformation is a reference to Edmund's first cat, as seen in some of his early videos on his personal channel.
	+ Guppy the cat passed away in 2014.
* Guppy appears to be a Maine Coon, due to the white blob on the head and the white marking ending around the chest.
* In the original Binding of Isaac, this transformation was called "Cursed?"
* Transforming into Guppy as  The Forgotten will give him the appearance of a cat's skeleton.
* The `guppy` item tag determines if an item counts towards the transformation, except for  which seems to be hard-coded to count as a Guppy item despite not having the tag.

## References

1. ↑ https://www.youtube.com/watch?v=trUCcvtN1lA
2. ↑ https://twitter.com/edmundmcmillen/status/501914984285077504
IV Bag

**IV Bag** is an activated item.

## Effects

* Upon use, causes Isaac to lose half a heart of health (or a full heart in Chapter 4 onward) while spawning coins.
	+ Each use pays out with 1-2 coins.
	+ Each use pays out with 1-2 coins on Normal mode or 1 coin on Hard mode.
	+ Spawns 0-1 coins instead when used by  Keeper.
	+ IV Bag takes Red Hearts before other heart types.

## Notes

* This item can be found when causing a Blood Donation Machine to explode by donating Hearts to it.
* This effect is counted as inflicted damage for items that spawn pickups upon said inflicted damage, such as  or , but does not decrease the chance of encountering the Devil Room / Angel Room.
* Invulnerability will not prevent Isaac from losing hearts.
* Can be used before taking damage (getting hit, walking over spikes, going through a Curse Room, etc.) to grant coins without inflicting extra damage.
	+ Also allows Isaac to avoid damage taken by using a Blood Donation Machine or Devil Beggar.
	+ Does not allow Isaac to avoid damage taken by using a Blood Donation Machine or Devil Beggar.
* Using this item as  The Lost will kill him.
* Using this item in Mirrored World kills Isaac.

## Synergies

* +  as  Judas /  Dark Judas: Gives a temporary +0.66 damage up with each use.
* : Spawns wisps in the outer ring, resembling coins. The wisps only have one health.
* : Rerolling the coins generated by IV bag can be used to generate unlimited pickups and items.
* + /: The damage from IV Bag has a chance to spawn 2 hearts, which can be picked up to create further coins and possibly even heal hearts with enough Luck.
	+ Humbleing Bundle only has a 50% chance to double the hearts dropped, but Old Bandage may still drop 1 heart.
* : Can be used without taking damage, resulting in an infinite amount of coins.
	+ Isaac still takes damage from this during  The Guardian (challenge #30).
* : Increases each payout to 2-3 coins.
	+ : Increases each payout to 2-3 coins on Normal mode and 2 on Hard mode.
* : Can be alternated between to gain ridiculous amounts of pickups from only a few initial coins or hearts.
* : Allows for infinite coins once Isaac is at half a red heart (or full red heart in Chapter 4 onward) by moving between rooms to reset Scapular's effect.

## Interactions

* : No effect.
* and similar items: IV Bag ignores the shield's protection, resulting in Isaac taking damage regardless.

## Gallery

* The icon of IV Bag as seen on the lower 3DS screen.

## Trivia

* A glitch in the original *The Binding of Isaac* existed where the player could leave a room and activate the item during the invincibility frames offered during recovery of using the items, effectively spawning infinite coins.
Meat Cleaver

Defeat The Witness as Isaac.

**Meat Cleaver** is an active item.

## Effects

* Splits all enemies in the room into 2 smaller versions of themselves with lower health.
	+ If their health is low enough, they will die instead.

## Notes

* The Meat Cleaver has special interactions when used on certain bosses or enemies.
	+ If used against Loki, he will split into two Lokiis instead of splitting into 2 smaller versions.
	+ If used against The Fallen during its first phase, it will split and instantly go into its second phase.
	+ If used against Chub, she will instantly die. This may be referred to as cutting her three segments apart.
	+ If used against a Mask + Heart, the mask will be destroyed, but the heart will be split. This can lead to a much easier time killing the heart, without needing to worry about the mask.
	+ If used against Mom, the cleaver will do nothing on her. However, the enemies she spawns will be split. The same thing applies to every other major final boss fight aside from The Witness in his second phase.
	+ If used against a Tinted Rock Spider, both resulting ennemies will drop a soul heart. This essentially doubles the reward.
	+ If used against a Moter, Squirt, Big Spider, Mama Guts, or MemBrain, they will instantly split into two Attack Flies, two Dips, two Spiders, two Guts, and two Brains, respectively.

## Gallery

* Meat Cleaver splitting Gaper in two smaller ones.

## Seeds

* FELT G16Q (First floor treasure room)
* 1JQ7 J3HH (Second floor treasure room)
Hungry Soul

**Hungry Soul** is an unlockable passive item added in *The Binding of Isaac: Repentance*.

## Effects

* Grants Isaac a chance to spawn a friendly ghost upon killing an enemy, which rapidly chases down and deals contact damage to enemies.
	+ The chance to spawn a ghost is 33% and is not affected by luck.
	+ Ghosts deal contact damage equal to half of Isaac's damage, 4 times per second (2x Isaac's damage per second).
* After 7 seconds, the ghost explodes, dealing 7 flat damage to nearby enemies up to 3-4 times.
	+ The explosion cannot damage Isaac or the environment.

## Notes

* Enemies killed by ghosts are unable to spawn more ghosts, except for those killed by the ghost's final explosion.
* The ghost's explosion is capable of damaging friendly monsters, such as Bonies summoned by .
* Ghosts cannot be taken outside the room they spawned in.
* The ghosts are not considered to be familiars and as such aren't affected by any items that modify the behavior of familiars.
	+ This also means that Isaac can have more than 64 ghosts at a time and this won't override other familiars.

## Interactions

* Ace Cards: Enemies that are turned into pickups can’t spawn ghosts.
* : No effect.
* /: Enemies that are turned into poop can’t spawn ghosts.
* : Ghosts cannot be sacrificed.
Hold

### Collection Grid

**Hold** is an activated item added in *The Binding of Isaac: Repentance*. It is available solely for  Tainted ??? as his starting item.

## Effects

* Removes  Tainted ???'s leftmost poop, storing it inside of Hold and cycling to the next poop.
* Using Hold again while a poop is inside it will remove the poop and use it as expected.

## Notes

* The item is unavailable for anyone except  Tainted ???.
	+ It can, however, activate when using . This does nothing with most characters; however, it *will* count as a use of the item when activated as  Tainted ???.
Hot Bombs

**Hot Bombs** is a passive item.

## Effects

* Isaac gains +5 Bombs on pickup.
* Placed bombs deal damage to enemies on contact and will leave behind a fire that damages enemies on contact upon exploding for 10 seconds.
	+ The fire does 22 damage per tick (66 damage per second).
	+ The fire can block four shots and/or deal four ticks of contact damage before expiring. It deals 23 damage at full durability, 17.25 damage after taking one hit, and 11.5 damage otherwise for a maximum damage of 63.25 damage.
	+ Fire from a Hot Bomb doesn't damage Isaac.
	+ Bombs deal 1 point of contact damage to enemies.
	+ Bombs deal 16 contact damage to enemies.
* Isaac can no longer take contact damage from static fires such as Fire Places. Fire projectiles still damage Isaac.
* Isaac produces a large circle of light, mitigating Curse of Darkness.

## Notes

* If a Hopper touches a Hot Bomb, it will become a Flaming Hopper.
* The contact damage does not scale with Isaac's damage and is completely removed if Isaac acquires another bomb item that overrides the flaming bomb graphic such as  or .
* Big Horn will throw Hot Bombs at Isaac that deal contact damage.
* If eaten by a boss such as Chub, a Hot Bomb will continously deal damage to the boss until it explodes.
* Negates the damage from the floor of lava in The Beast's chamber, but not from its fire inhalation attack.

## Synergies

* /  /  /  / : These explosions are affected by Hot Bombs.
* : Bombs leave behind nine fires in a cross shaped pattern.
* /  / : Bombs/missiles are affected by Hot Bombs.
* Red Locusts: Red locust explosions are affected.
* : Allows for maximization of contact damage, especially if an enemy gets stuck on a bomb.
* : Each additional explosion creates a fire.
	+ Fires from extra bombs now start with 1 less durability.

## Interactions

* /  / : Bombs/missiles are not affected by Hot Bombs.
* : Ipecac shots are unaffected.

## Trivia

* Orange champion  Little Horn summons bombs that are identical in function, but given the Troll Bomb sprite and colored orange.