Lori Grimes/Season 1

When the camp received on the radio an emergency broadcast from a man on his way to Atlanta, Lori suggested that perhaps they should post signs on the road to warn people away from the city. After Shane disagreed with her idea saying that it was very dangerous, Lori headed to her tent and he followed her to remind her that she couldn't risk her life because of her son, and then they ended up reconciling with a passionate kiss. ("Days Gone Bye")

Some hours later, Lori asked Dale to watch Carl with the excuse of looking some mushrooms and met with Shane secretly in the woods to have sex, although for a moment they felt uncomfortable after noticing Rick's wedding ring in a locket around her neck. Later that day, while doing the laundry, the camp received T-Dog's distorted distress message. Lori listened as Shane refused to send a rescue team and went after Amy to comfort her. ("Guts")

When Rick reappeared in the camp with the group that had traveled to the city for supplies, Lori was surprised to see her husband alive and well and embraced him, although she began to feel confused and guilty over her romance with Shane. That night, Lori returned to Rick his wedding ring and they made love after reconciling. The next day, while Rick and some group members returned to Atlanta to rescue Merle Dixon despite her protests, Lori confronted Shane and warned him to stay away from her family due to lying to her about her husband's death, claiming he had lost his right to talk to her. ("Tell It to the Frogs")

Lori congratulated Andrea and Amy when they arrived back from the lake with several caught fish for dinner. After Dale informed everyone at the camp about a paranoid Jim digging holes without an explanation, Lori witnessed as Shane subdued him and tied him to a tree until he would feel better. Shortly after, Jim apologized to Lori for his behavior but ominously warned that she had to protect Carl. That night, everyone was reunited around a campfire as they listened to Dale's stories. When the camp was attacked by several walkers, Lori and Carl were protected by Shane until Rick and the others returned in time to help defend the place. ("Vatos")

The next morning, Lori was against Rick's idea of ​​going to the CDC to find a cure for Jim, who had been bitten during the attack, since she didn't know if she could blindly follow him. After Rick told her the only thing he was certain of was his love for her, Lori decided to support his decision and his role as the new leader. Although Shane later criticized her for only thinking about her marriage, Lori refused to listen to him. The next day, Lori was present in the last camp meeting where she said goodbye to the Morales family. While the remaining group of survivors departed towards the CDC, they left an agonizing Jim under a tree by the road as his last wish. Upon arriving at their destination, they found everything abandoned. As some walkers began to approach them, Lori tried to convince Rick to leave when suddenly the doors opened in time. ("Wildfire")

Upon entering the CDC, Lori and the others were reluctantly welcomed by the sole remaining employee, Dr. Edwin Jenner, who allowed them to stay in exchange for some blood tests. That night, the group had a feast in the cafeteria and enjoyed all the luxuries the facility had to offer, beyond happy about having found a safe place. Lori and Rick shared a hot shower and then they each decided to go explore the place. While visiting the library alone, Lori was confronted by a drunken Shane, who kept insisting that they belonged together, and was forced to scratch him in his neck when he attempted to sexually abuse her. The next morning, Lori and the group learned that the virus that had caused the outbreak erased any conscious human traits from someone infected.

When the power generators began to ran out of fuel, Jenner revealed that the facility would explode due to a self-destruct protocol and then sealed everyone inside the control room, explaining that it would be a quick and painless death. Lori comforted a crying Carl while pleading him to allow them to leave, claiming that they deserved another chance to survive as long as they could. After Rick eventually made Jenner change his mind, the survivors ran in a hurry to escape. Upon finding the top doors locked, Carol handed Rick a grenade she had found in his uniform and everyone took cover as he used it to blast one of the windows. Lori and the group escaped as the CDC exploded and then continued their journey towards a new destination. ("TS-19")