Jemma Simmons

*"The steps you take don't need to be big, they just need to take you in the right direction."*
―Jemma Simmons[src]
Doctor **Jemma Anne Simmons** is a genius biochemist and was one of the youngest and most prominent members of S.H.I.E.L.D.'s research division. Along with Leo Fitz, Simmons was recruited to Coulson's Team and worked with them on all of their missions. While on the team, Simmons became friends with Grant Ward and best friends with Skye. During the HYDRA Uprising, Simmons was an active participant in hunting for John Garrett and the rest of the Centipede Project. She was shocked and saddened to learn that Ward had been a member of HYDRA. Despite the events surrounding the Battle at Cybertek and Fitz's severe injury, Simmons stayed with the team to help rebuild S.H.I.E.L.D. as Nick Fury requested.

As Coulson began to rebuild S.H.I.E.L.D., she became aware that her presence was impeding Fitz's healing and took an undercover assignment to infiltrate HYDRA, but returned to S.H.I.E.L.D. when Raina broke her cover. She aided the team in their search for the Kree City and in other operations. When the Playground was attacked by another S.H.I.E.L.D. faction led by Robert Gonzales, she remained loyal to Coulson. After the War Against the Inhumans, Simmons found herself teleported to Maveth after being swallowed by the Monolith.

In the six months she spent there, Simmons met and fell in love with Will Daniels, until she was brought back to Earth by Fitz and S.H.I.E.L.D.. Simmons then dedicated her time to attempt to reopen the portal, determined to bring back Daniels, only to hear from Fitz that he was killed by Hive who managed to return to Earth. Fitz and Simmons tried to find a cure to Hive's power of controlling Inhumans' minds before S.H.I.E.L.D. eventually managed to kill Hive.

Jeffrey Mace was appointed S.H.I.E.L.D.'s new Director after the signing of the Sokovia Accords. Although she did not trust him, he appointed Simmons as his advisor in science and technology, which led to her becoming one of the superiors in the organization. Simmons investigated the existing of another dimension and helped S.H.I.E.L.D. to defeat Eli Morrow. With Holden Radcliffe's betrayal of S.H.I.E.L.D. and his kidnapping of most of her friends, Simmons and Daisy Johnson entered the Framework in order to rescue them. They succeeded and they all returned to the real world but had to face against the threat of the now living Aida. S.H.I.E.L.D. stopped the crazed Inhuman, but Simmons and others were sent to the year 2091 afterwards.

The team found themselves in a bunker located in the ruins of Earth called the Lighthouse and Simmons ended up becoming a servant of Kasius. She was later freed by Fitz who managed to come from the past to save her and the two engaged. Eventually, she and the others managed to return to the present, where she and Fitz would soon be married by Coulson. They worked to prevent the Destruction of Earth, came into conflict with HYDRA led by Hale and later with the Confederacy. They managed to kill Glenn Talbot, thus saving Earth; however, Fitz lost his life in the battle. Simmons followed Alphonso Mackenzie as S.H.I.E.L.D.'s new Director, searching for the present-day Fitz frozen in space.

The search lasted for a year to no prevail. However, Simmons forced the mission to continue which resulted in them being captured by the Chronicoms and be reunited with Fitz. The Chronicoms used them to help them achieve time travel, but they were able to escape and were recruited by Izel, who helped them get back to Earth. However, they learnt that Izel was intending to unleash her forces upon Earth, and they were rescued by S.H.I.E.L.D.. They continued to fight against Izel, as well as engage in an uneasy alliance with Sarge, who looked exactly like Coulson. While S.H.I.E.L.D stopped Izel and Sarge, Simmons and Fitz were ambushed by the Chronicom Hunters, and were saved by Enoch who helped them achieve time travel as well as create a Phil Coulson LMD to help them fight the Hunters.