Jean Grey

* Alex Power - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Alicia Masters - X-Men are manipulated into attacking Alicia and Fantastic Four (FaFo #28) and they meet at the Richards engagement party (#36) and wedding (An. #3)
* Amanda Sefton - first met for New Years in New York (X-Men #98), and Amanda was at the wedding of Jean and Scott (X-Men #2.30)
* Ancient One - the X-Men hear of the Ancient One in X-Men #33
* Angel - original X-Men (XM #1-94) and X-Factor members, and in X-Men again (from UXM #375). Nickname: "Blondie" (UXM #132)
* Anole - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Ant-Man - many team crossovers (since X-Men #9)
* Apocalypse - *Enemy:* major villain of X-Factor (from #6)
* Armor - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Artie Maddicks - Artie was adopted by X-Factor (from XF #3). Nickname: "Artie Baby" (XF #15)
* Attuma - *Enemy*: Attuma abducts Jean and her sister in an attempt to use them as breeders (Bizarre Adventures #27), and they battle in Atlantis again as Attuma abducts her one more time (X-Factor An. #4)
* Avalanche - their two teams clash over Rusty Collins in Central Park (X-Factor #9) and in Dallas over the fate of Nathan Christopher (#31), but also meet on more amicable terms (#33)
* Banshee - clashed in X-Men #28 but allies since Krakoa (GSX#1), members of X-Men (#97-129, again from U X-Men #280)
* Beast - founders of X-Men (#1-66) and X-Factor, and in X-Men again (from #375). Nickname: "Fuzzball" (X-Factor #1), "Fuzzy" (#46)
* Beetle - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Bishop - members of X-Men (from #287)
* Black Bolt - they join forces to free Franklin Richards from Maximus in Attilan (X-Factor An. #2)
* Black Knight - they met at the wedding of Wasp and Ant-Man (Avengers #60), also X-Factor battle a set of alien fake Avengers (XF #32)
* Black Panther - they clash in the fortress of Magneto (Avengers #53), later again battle but then join forces against the mind-control of Magneto (#110-111)
* Black Widow - Avengers and X-Men battle but then join forces against the mind-control of Magneto (A #111), later their teams join forces in Onslaught (X-Men #2.55), and they are involved in the chaotic battles leading to Wolverine marrying Viper (W #125)
* Blindfold - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Blob - *Enemy:* classic foe of the X-men (from #3)
* Boom-Boom - she was trainee in X-Factor (from #12), and X-Force move into the X-mansion (from X-Force #44)
* Cable - Scott first shows Jean a picture of baby Nathan (X-Factor #8), then X-Factor liberates and adopts baby Nathan after Inferno (#37-39), later they battle Ahab (An. #5), and work together (Cable #21), X-Force live in the mansion (from XF #44), finally members of X-Men (from #375). Nickname (for baby Nathan): "My Precious" (XF #48), "Babydoll" (#59)
* Caliban - *Ally*: Caliban becomes trainee in X-Factor after being saved from the Mutant Massacre (Power Pack #27), and also X-Force reside in the mansion (from XF #44) - *Enemy*: adversaries in the Apocalypse Twelve event (X-Men #377-379)
* Callisto *- Ally:* they join forces against Masque (X-Men #263) and Genoshans (#264) - *Enemy:* Callisto again attacks the X-Men (U #293)
* Cannonball - the New Mutants are based on X-Factor's "Ship" (from NM #76) and X-Force also reside with the X-Men (X-Force #18-19), finally X-Men (from XF #44)
* Captain America - many team crossovers (since X-Men #9)
* Captain Britain - they brief each other by video over the Kings of Pain disaster in Edinburgh (X-Factor An. #6)
* Celeste Cuckoo - residing at the X-Mansion at the same time (in New X-Men and from All-New X-Men #5)
* Chamber - members of X-Men (#407-423)
* Charles Xavier - they met when she was young (retcon of Bizarre Adventures #27 and X-Men #-1). Original X-Men (#1-137 and later). Became his closest confidante in the team ever since he secretly trained her in telepathy (#40)
* Ch'od - joined forces on the nameless planet in the Phoenix saga (X-Men #107-108)
* Cobra - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Colossus - joined forces on Krakoa (GSX#1), members of X-Men (#97-137 and until #390). Nickname: Dark Phoenix calls him "Little Brother" in #136, presumably to mock him (Ororo began calling him Little Brother in #119)
* Corsair - joined forces on the nameless planet in the Phoenix saga (X-Men #107-108)
* Count Nefaria - *Enemy:* Nefaria abducted the X-Men in #22-23
* Crystal - they met at the wedding of Wasp and Ant-Man (Avengers #60) and Jean's own wedding (X-Men #2.30) and their teams join forces in Onslaught (X-Men #2.55)
* Cyclops - original X-Men (#1-137) and X-Factor members, then again X-Men. Life partner (from X-Men #53), he proposes (XF #53) and spouse (XM #2.30). Nickname: "My Darling" (XM #35 privately), "Lover" (#242), "Slim" (#2.35 to 2.71), "Fearless Leader" (#2.38), "Husband-o-mine" (Wolverine #116)
* Daredevil - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3) and the wedding of Wasp and Ant-Man (Avengers #60), and Daredevil battles and frees X-Men from the mind-control of Magneto (#111)
* Dazzler - joined forces when Alison was first discovered (X-Men #130), during Inferno (#242-243), and against Magneto in Genosha (#392-393)
* Doctor Druid - X-Factor battle a set of alien fake Avengers (XF #32)
* Doctor Strange - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3), allies several times (since X-Men #33)
* Domino - Domino was at the wedding of Jean and Scott (X-Men #2.30), they work together in the ruins of Murderworld (Cable #21), and X-Force reside in the mansion (from XF #44)
* Dormammu - Jean and Scott use Dormammu's name in an incantation learned from Doctor Strange (X-Men #33)
* Doug Ramsey - Jean discusses the death of Doug in X-Factor #65
* Dust - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Edwin Jarvis - they met at the wedding of Wasp and Ant-Man (Avengers #60), and he is there when she bursts her cocoon (FF #286)
* Electro - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Elektra - Jean senses her presence in the battle against Ozymandias (Wolverine #101)
* Emma Frost - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129), later Jean inhabits Emma's body (#282) - *Ally*: Both members of X-Men
* Enchantress - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Executioner - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Firelord - Firelord attacks the X-Men in #105-106. Nickname: "Herald" (#105)
* Foggy Nelson - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3), Nelson visits the mansion to read the final will of the professor (X-Men #46)
* Forge - Jean first sees Forge on TV from Dallas (X-Factor #27), they join forces against Ahab from the future (An. #5), later X-Men members (from XM #263)
* Franklin Richards - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2) adn several times more
* Frenzy - *Enemy:* Frenzy and Alliance of Evil are major foes of X-Factor (from #4) - *Ally:* Frenzy joins the X-Men in battle against Magneto in Genosha (U X-Men #392-393)
* Galactus - she first hears of Galactus from Firelord in X-Men #104, and later again in X-Men UL #13
* Gambit - they join forces against Ahab and his hounds (X-Men An. #14), and X-Men members (#280-350). Nickname: "Mon Brave" (#382)
* Genesis - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Gladiator - they fought over Majestrix Lilandra in X-Men #107-108 and over Phoenix in #137
* Glenn Talbot - Major Talbot clashes with the X-Men over Hulk in X-Men #66
* Glob Herman - both residents at the X-Mansion
* Gorgon - they join forces to free Franklin Richards from Maximus in Attilan (X-Factor An. #2)
* Grey Gargoyle - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Guardian - both are at the X-Mansion when Hudson is studying Wolverine (W #92-95)
* Havok - allies through X-Men many times since #54, full members from #65-94, and brother-in-law
* Hawkeye - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3), occasional team crossover (e.g. Avengers #53 and X-Men #2.55)
* Hela - Wolfsbane tells X-Factor members of Hela's attempted coup (New Mutants #88)
* Hellion - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Hepzibah - joined forces on the nameless planet in the Phoenix saga (X-Men #107-108)
* Hercules - he aids Jean after she bursts out of her cocoon (FF #286)
* High Evolutionary - the X-Men liberate the Evolutionary from Sinister's capture (X-Men #379)
* Hulk - first hears of Hulk from Iron-Man (Avengers #3), they have clashed (X-Men #66), later their two teams meet at the X-Mansion in All-New X-men #8
* Human Torch - many team meetups (since Fantastic Four #28)
* Husk - both residing at the X-Mansion (from around X-Men #410)
* Iceman - founders of X-Men (#1-94) and X-Factor, again X-Men (from #377)
* Iron-Man - many team crossovers (since Tales of Suspense #49)
* Jack Power - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Jubilee - allies since X-Tinction (U X-Men #272) and as X-Men (from #2.5)
* Juggernaut - *Enemy:* arch enemy since X-Men #12 - *Ally:* against Onslaught (X-Men #2.54), and then both residing at the X-Mansion (from #413)
* Julia Carpenter - their two teams battle over Rusty Collins in Central Park (X-Factor #9)
* Julie Power - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Kang - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Karen Page - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Karnak- they join forces to free Franklin Richards from Maximus in Attilan (X-Factor An. #2)
* Katie Power - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Ka-Zar - friends and allies ever since X-Men #10
* Kid Omega - residing at the X-Mansion at the same time
* Kingpin - they collide in Hong Kong in X-Men #2.63-2.64
* Lady Deathstrike - Banshee tells Jean about Deathstrike and the Reavers (X-Men #262), they have a meet-up with Wolverine just when Yuriko becomes possessed (W #114)
* Leech - Leech is adopted by X-Factor after being saved from the Mutant Massacre (Power Pack #27)
* Lilandra - allies, sometime foes, since Lilandra first came to Earth in the Phoenix saga (X-Men #105)
* Longshot - Jean first sees him on TV from Dallas (X-Factor #27), they join forces during Inferno (X-Men #242-243)
* Luna Maximoff - they meet in Attilan when Lockjaw brings X-Men there (X-Factor An. #2), and the X-Men work to save Luna in Bloodties (X-Men #2.26)
* Madelyne Pryor - *Enemy:* she is a clone of Jean, who first hears about Maddie from the X-Factor guys (#7), sees her picture (#8) and watches her on TV from Dallas (#27), they battle during Inferno (X-Factor #37-39). Nickname: "Witch" (#38)
* Mad Thinker - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Magik - Jean hears Colossus talk about Illyana in X-Men #2.108
* Magma - Jean sees Magma at the Xavier Institute after she has been assaulted (X-Men #423)
* Magneto - *Enemy:*archenemy of the X-Men - *Ally*: against Apocalypse in the Apocalypse Twelve event (X-Men #377)
* Mandarin - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3), later she hears of Mandarin when in Hongkong (#2.104)
* Marrow - members of X-Men (from #2.70)
* Mastermind - *Enemy:* classic foe of the X-Men (from #4) and orchestrated her personal downfall (from #122)
* Maximus - *Enemy*: X-Men attack Maximus to free Franklin Richards in Attilan (X-Factor An. #2)
* Medusa - they join forces to free Franklin Richards from Maximus in Attilan (X-Factor An. #2)
* Meggan - Brian Braddock tells Meg about Jean, and Meg goes on to impersonate her (Excalibur #33)
* Mercury - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Mindee Cuckoo - residing at the X-Mansion at the same time (in New X-Men and from All-New X-Men #5)
* Mirage - the New Mutants are briefly based on X-Factor's "Ship" (around NM #76), and they also meet at the wedding of Havok and Polaris (X-Men #425)
* Mister Hyde - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Mister Sinister - *Enemy:* the pantheon of mutants defeat Sinister after Inferno (X-Factor #39), and later X-Men defeat Sinister again on the space station of the High Evolutionary (X-Men #380)
* Misty Knight - roommates in Greenwich Village (before X-Men #102 until #117)
* Moira MacTaggert - Jean first mentions Moira (X-Men #97), and X-allies ever since, also lived on Muir Island (#119-129)
* Mole Man - *Enemy:* X-Men battle Mole Man in the Baxter Building (Fantastic Four An. #3) and in the underground realms (X-Men #34)
* Morbius - *Enemy:* they battle over Spider-Man in Marvel Team-up #4
* Multiple Man - friends and allies since they lived on Muir Island together (X-Men #119-129)
* Mystique - their two teams battle over Rusty Collins in Central Park (X-Factor #9) and in Dallas over the fate of Nathan Christopher (#31), also meet on amicable terms (#33), finally join forces in the Muir Island Saga (#69)
* Nick Fury - they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3), later they join forces several times (e.g. X-Men #2.2-3 and #35)
* Nightcrawler - joined forces on Krakoa (GSX#1), members of X-Men (#97-137) and again later
* Northstar - he joins the X-Men in battle against Magneto in Genosha (X-Men #392-393), and soon both are members of X-Men (from #414)
* Oya - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Phoebe Cuckoo - residing at the X-Mansion at the same time (in New X-Men and from All-New X-Men #5)
* Pixie - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Polaris - allies ever since X-Men #49, members of X-Men (from #60-94 and #377-379)
* Psylocke - Jean first sees her on TV from Dallas (X-Factor #27), they join forces during Inferno (X-Men #242-243), later X-Men members (from #280)
* Puck - Jean is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Punisher - the X-Men talk about Punisher in X-Men #2.104
* Puppet Master - *Enemy:* Mad Thinker and Puppet Master manipulate X-Men and Fantastic Four to fight each other (FaFo #28), later they battle again (XM #27)
* Pyro - their two teams battle over Rusty Collins in Central Park (X-Factor #9) and in Dallas over the fate of Nathan Christopher (#31), but also meet on more amicable terms (#33)
* Quicksilver - many meetings both ally and foe since the first Brotherhood vs X-Men (from X-Men #4)
* Rachel Summers - her daughter from a future timeline, in our time they meet on Liberty Island after Rachel's fight with future Franklin (X-Factor An. #5)
* Raza - joined forces on the nameless planet in the Phoenix saga (X-Men #107-108)
* Reed Richards - many team meetups (since Fantastic Four #28)
* Rick Jones - they meet at the Richards engagement party (Fantastic Four #36)
* Rictor - he was trainee in X-Factor (from XF #17)
* Rockslide - residing at the X-Mansion at the same time (from All-New X-Men #5)
* Rogue - Jean first sees Forge on TV from Dallas (X-Factor #27), they join forces during Inferno (X-Men #242-243), later X-Men members (from #280)
* Roma - Jean hears Madelyne Pryor talk about Roma during Inferno (X-Factor #38)
* Sabretooth - *Enemy:*  Jean is there when Sabretooth is "killed" at X-Mansion (X-Factor #39), and X-Men later hold him captured at the mansion (X-Men #2.33-38)
* Sasquatch - Jean is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Sauron - *Enemy:* classic foe ever since X-Men #60
* Scarlet Witch - many meetings both ally and foe since the first Brotherhood vs X-Men (from X-Men #4)
* Sebastian Shaw - *Enemy:* iconic foe of the Dark Phoenix years (X-Men #129)
* Selene - *Enemy:* Selene plots against the X-Men (U X-Men #283)
* Shadowcat - Kitty was first saved by Jean and the X-Men (in #131), later both X-Men (until #390, and from All-New X-Men #5)
* Shaman - Dr. Twoyoungmen treats Jean in Anchorage in U X-Men #359
* Shang-Chi - they join forces in Hong Kong (X-Men #2.62-2.63)
* Sharon Ventura - they meet when they defeat Ahab from the future together (X.Factor An. #5)
* Shatterstar - their two teams clash in X-Cutioner's Song (U X-Men #295), but X-Force also reside with the X-Men (X-Force #18-19 and from #44)
* She-Hulk - X-Factor battle a set of alien fake Avengers (XF #32), later Jennifer seeks to represent the mutants in the Genosha trials in (X-Men #272)
* Silver Surfer - they join forces against the Inciters in X-Men UL #13
* Siryn - they join forces against Proteus (X-Factor An. #6), battle on Muir Island (U X-Men #280) and X-Cutioner's Song (#295), but X-Force also briefly stay with the X-Men (X-Force #18-19)
* Skin - she sees the corpse of Skin at the Xavier Institute after he has been assaulted (X-Men #423)
* Snowbird - Jean is presumably at the Xavier Institute when Alpha Flight show up to collect Sammy Paré (X-Men #422)
* Spider-Man - some team meetups since X-Men first heard of Spidey (An. SM #1) and they meet at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Spider-Woman (JD) - they are involved in the chaotic battles leading to Wolverine marrying Viper (W #125), and their two teams meet at the X-Mansion in All-New X-men #8
* Spiral - *Enemy:* Jean sees Spiral briefly in Central Park (X-Factor #8) and they clash in Dallas over the fate of Nathan Christopher (#31), but also meet on more amicable terms (#33)
* Storm - first joined forces on Krakoa (GSX#1), members of X-Men (#97-137), and best friends (from #100). Storm is her maid of honour (X-Men #2.30)
* Strong Guy - Guido joins forces with the X-Men several times (U X-Men #278-295)
* Sub-Mariner - Namor meets the X-Men on Magneto's island (XM #6) and meets X-Factor on "Ship" after the Kraken has been defeated (New Mutants #76)
* Sunfire - Sunfire first battled against the X-Men in Manhattan (#64), but allies in GSX#1 and U X-Men #284
* Sunspot - the New Mutants are based on X-Factor's "Ship" (from NM #76), allies in Genosha (X-Men #272), they clash in X-Cutioner's Song (#295), but X-Force also reside with the X-Men (X-Force #18-19 and from #44)
* Super-Skrull - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Susan Richards - many team meetups (since Fantastic Four #28)
* Tessa - they met when Jean was at Hellfire Club (X-Men #132-133), and again at the Xavier Institute (X-Treme X-Men #23)
* The Thing - many team meetups (since Fantastic Four #28)
* The Watcher - in Attilan, Karnak mentions the Watcher (X-Factor An. #2)
* Thor - many team crossovers (since X-Men #9)
* Toad - *Enemy:* classic foe of the X-Men (from #4)
* Trish Tilby - they meet as she covers X-Factor (from #7) and at the mansion in X-Men #2.70-2.71
* Triton - they join forces to free Franklin Richards from Maximus in Attilan (X-Factor An. #2)
* Valerie Cooper - Valerie sends X-Factor on special mission to Genosha (XF #60), they also join forces in X-Cutioner's Song (U X-Men #295)
* Vanisher - *Enemy:* classic foe of the X-men (from #2)
* Vindicator - both are at the X-Mansion when Hudson is studying Wolverine (W #92-95)
* Viper - they are involved in the struggles leading to Wolverine marrying Viper (W #125)
* Vision - they meet at the wedding of Wasp and Ant-Man (Avengers #60), Avengers and X-Men battle but then join forces against the mind-control of Magneto (#110-111), and join forces in Onslaught (X-Men #2.55)
* Warlock - the New Mutants are based on X-Factor's "Ship" (from NM #76)
* Warpath - their two teams clash in X-Cutioner's Song (U X-Men #295), but X-Force also reside with the X-Men (X-Force #18-19 and from #44)
* Wasp - many team crossovers (since X-Men #9)
* Whirlwind - *Enemy*: they take part in the big battle at the wedding of Reed and Susan Richards (Fantastic Four An. #3)
* Wolfsbane - the New Mutants are based on X-Factor's "Ship" (from NM #76), they also meet during the Genosha X-Tinction events (X-Men #272)
* Wolverine - first joined forces on Krakoa (GSX#1), then X-Men (#97-137, again later). Nickname: "Short-stuff" (XM #134)
* X-Man - they travel together in Alaska after Age of Apocalypse (X-Man #54), also briefly members of X-Men (#375-379)