1850s

## 1850

* January 28 – Samuel Johnson Pugh born.
* March 7 – Champ Clark born.
* May 27 – Micah Taul died, aged 65.
* July 9 – Zachary Taylor died, aged 65.
* July 15 – Thomas Stivers born.
* July 22 – Manlius Valerius Thomson died, aged 47.
* July 31 – John J. Crittenden left office as Governor of Kentucky.
* July 31 – John L. Helm entered office as 18th Governor of Kentucky.
* September 8 – Henry Bidleman Bascom died, aged 54.
* September 12 – Presley Neville O'Bannon died, aged ~74.
* September 20 – Thomas Young Fitzpatrick born.
* October 30 – Robert Burns Wilson born.
* November 11 – Bishop Benedict Joseph Flaget died, aged 87.
* November 19 – Richard Mentor Johnson died, aged 70.

## 1851

* January 24 – Marcus Aurelius Smith born.
* February 22 – Richard Gruelle born.
* March 4 – James Leeper Johnson left office as US House of Representatives from Kentucky, 2nd District.
* March 4 – Finis McLean left office as US House of Representatives from Kentucky, 3rd District.
* March 4 – George Caldwell left office as US House of Representatives from Kentucky, 4th District.
* March 4 – John Burton Thompson left office as US House of Representatives from Kentucky, 5th District.
* March 4 – Daniel Breck left office as US House of Representatives from Kentucky, 6th District.
* March 4 – Charles S. Morehead left office as US House of Representatives from Kentucky, 8th District.
* March 4 – Benjamin E. Grey entered office as US House of Representatives from Kentucky, 2nd District.
* March 4 – Presley Underwood Ewing entered office as US House of Representatives from Kentucky, 3rd District.
* March 4 – William T. Ward entered office as US House of Representatives from Kentucky, 4th District.
* March 4 – James W. Stone entered office as US House of Representatives from Kentucky, 5th District.
* March 4 – Addison White entered office as US House of Representatives from Kentucky, 6th District.
* March 4 – John C. Breckinridge entered office as US House of Representatives from Kentucky, 8th District.
* April 25 – Joseph Lecompte died, aged 53.
* June 6 – Sister Elisabeth Wells died, aged unknown.
* September 2 – John L. Helm left office as Governor of Kentucky.
* September 2 – Lazarus W. Powell entered office as 19th Governor of Kentucky.
* October 22 – William P. Taulbee born.
* November 29 – William Worth Dickerson born.
* December 1 – Linn Boyd became 20th Speaker of the US House of Representatives.
* December 9 – Thomas Hanson Paynter born.
* December 18 – William E. Applegate born.

## 1852

* February 14 – Thomas Carlin died, aged 62.
* March 30 – Philip Triplett died, aged 52.
* May 5 – Julia Britton Hooks born.
* June 29 – Henry Clay died, aged 75.
* June 29 – Henry Clay left office as US Senator from Kentucky.
* July 5 – John W. Tibbatts died, aged 50.
* July 6 – David Meriwether entered office as US Senator from Kentucky.
* July 19 – John McKinley died, aged 72.
* July 21 – Stephen Chipley died, aged 67.
* August 4 – Humphrey Marshall left office as US House of Representatives from Kentucky, 7th District.
* August 14 – Margaret Taylor died, aged 63.
* August 18 – Margaret Mackall Smith Taylor died, aged 63.
* August 31 – David Meriwether left office as US Senator from Kentucky.
* September 1 – Archibald Dixon entered office as US Senator from Kentucky.
* September 21 – John Chambers died, aged 71.
* September 24 – Benjamin Hardin died, aged 68.
* October 3 – James Sprigg died, aged ~50.
* October 15 – John Calhoon died, aged 59.
* October 27 – Nathan T. Hopkins born.
* October 29 – Edward J. McDermott born.
* November 2 – Lorimer Johnston born.
* December 6 – William Preston entered office as US House of Representatives from Kentucky, 7th District.

## 1853

* February 19 – Elizabeth Hardin died, aged 66.
* March 4 – Joseph R. Underwood left office as US Senator from Kentucky.
* March 4 – William T. Ward left office as US House of Representatives from Kentucky, 4th District.
* March 4 – James W. Stone left office as US House of Representatives from Kentucky, 5th District.
* March 4 – Addison White left office as US House of Representatives from Kentucky, 6th District.
* March 4 – John C. Mason left office as US House of Representatives from Kentucky, 9th District.
* March 4 – John B. Thompson entered office as US Senator from Kentucky.
* March 4 – James Chrisman entered office as US House of Representatives from Kentucky, 4th District.
* March 4 – Clement S. Hill entered office as US House of Representatives from Kentucky, 5th District.
* March 4 – John Milton Elliott entered office as US House of Representatives from Kentucky, 6th District.
* March 4 – Leander Cox entered office as US House of Representatives from Kentucky, 9th District.
* May 27 – Francis Alexander Hopkins born.
* June 9 – James William Bryan born.
* July 21 – Thomas P. Moore died, aged ~56.
* September 5 – Bland Ballard died, aged 91.
* October 1 – Patty Prather Thum born.
* October 10 – William S. Taylor born.
* December 23 – Young E. Allison born.

## 1854

* February 4 – Andrew McConnell January Cochran born.
* February 6 – McLean County formed by Kentucky Legislature.
* March 9 – John Stockdale Rhea born.
* March 19 – William Pope Duval died, aged 69.
* May 1 – Richard French died, aged 61.
* June 4 – Ida Marie Honoré born.
* June 6 – John Speed Smith died, aged 61.
* June 24 – Henry Dixon Allen born.
* July 18 – Tom L. Johnson born.
* September 27 – Presley Ewing died, aged 32.
* September 27 – Presley Ewing left office as US House of Representatives from Kentucky, 3rd District.
* October 12 – London Ferrill died, aged ~65.
* December 4 – Francis Bristow entered office as US House of Representatives from Kentucky, 3rd District.
* December 19 – David Highbaugh Smith born.
* December 28 – James Turner Morehead died, aged 57.

## 1855

* January 5 – Johnson Newlon Camden, Jr. born.
* January 6 – Tunstall Quarles died, aged ~85.
* February 11 – S. Thruston Ballard born.
* March 4 – Archibald Dixon left office as US Senator from Kentucky.
* March 4 – Linn Boyd left Speaker of the US House of Representatives position.
* March 4 – Linn Boyd left office as US House of Representatives from Kentucky, 1st District.
* March 4 – Benjamin E. Grey left office as US House of Representatives from Kentucky, 2nd District.
* March 4 – Francis Bristow left office as US House of Representatives from Kentucky, 3rd District.
* March 4 – James Chrisman left office as US House of Representatives from Kentucky, 4th District.
* March 4 – Clement S. Hill left office as US House of Representatives from Kentucky, 5th District.
* March 4 – William Preston left office as US House of Representatives from Kentucky, 7th District.
* March 4 – John C. Breckinridge left office as US House of Representatives from Kentucky, 8th District.
* March 4 – Richard H. Stanton left office as US House of Representatives from Kentucky, 10th District.
* March 4 – John J. Crittenden entered office as US Senator from Kentucky.
* March 4 – Henry Cornelius Burnett entered office as US House of Representatives from Kentucky, 1st District.
* March 4 – John P. Campbell, Jr. entered office as US House of Representatives from Kentucky, 2nd District.
* March 4 – Warner Underwood entered office as US House of Representatives from Kentucky, 3rd District.
* March 4 – Albert G. Talbott entered office as US House of Representatives from Kentucky, 4th District.
* March 4 – Joshua Jewett entered office as US House of Representatives from Kentucky, 5th District.
* March 4 – Humphrey Marshall entered office as US House of Representatives from Kentucky, 7th District.
* March 4 – Alexander Marshall entered office as US House of Representatives from Kentucky, 8th District.
* March 4 – Samuel F. Swope entered office as US House of Representatives from Kentucky, 10th District.
* March 23 – George Mosby Davison born.
* June 25 – Gerard Fowke born.
* July 10 – Mitchell Cary Alford born.
* July 13 – Robert Young Thomas, Jr. born.
* August 6 – Bloody Monday, the Know-nothing riots in Louisville.
* August 18 – Thomas Metcalfe died, aged 75.
* September 4 – Lazarus W. Powell left office as Governor of Kentucky.
* September 4 – Charles S. Morehead entered office as 20th Governor of Kentucky.
* November 1 – Edward Mann Butler died, aged 71.

## 1856

* January 4 – William Geobel born.
* February 10 – Ingram Crockett born.
* February 11 – Eliza Calvert Hall born.
* February 16 – Byrd Spillman Dewey born.
* April 20 – James C. Crow died, aged ~66.
* May 24 – John Marhsall born.
* June 7 – Morris B. Belknap born.
* July 16 – James Greene Hardy died, aged 61.
* September 8 – Nannie Kelly Wright born.
* October 22 – William Hopkinson Cox born.
* November 13 – Louis Brandeis born.
* December 17 – John Telemachus Johnson died, aged 68.

## 1857

* March 4 – John P. Campbell, Jr. left office as US House of Representatives, 2nd District.
* March 4 – Alexander Marshall left office as US House of Representatives, 8th District.
* March 4 – Leander Cox left office as US House of Representatives, 9th District.
* March 4 – Samuel F. Swope left office as US House of Representatives, 10th District.
* March 4 – John C. Breckinridge entered office as 14th US Vice President.
* March 4 – Samuel Peyton entered office as US House of Representatives, 2nd District.
* March 4 – James Brown Clay entered office as US House of Representatives, 8th District.
* March 4 – John C. Mason entered office as US House of Representatives, 9th District.
* March 4 – John W. Stevenson entered office as US House of Representatives, 10th District.
* March 29 – Samuel Brenton died, aged 46.
* June 10 – Mrs. Leslie Carter born.
* November 4 – William Preston Kimball born.
* December 29 – Thomas Cruse born.

## 1858

* February 11 – Cattlettsburg incorporated.
* February 28 – Richard Pretlow Ernst born.
* March 3 – Monk Cline born.
* March 19 – Ben Johnson born.
* June 19 – John Eugene Osborne born.
* July 1 – James Montgomery Richardson born.
* July 15 – John Kerins born.
* August 9 – Christopher Tompkins died, aged 78.
* September 3 – Chilton Allan died, aged 72.

## 1859

* March 4 – John B. Thompson left office as US Senator from Kentucky.
* March 4 – Warner Underwood left office as US House of Representatives from Kentucky, 3rd District.
* March 4 – Albert G. Talbott left office as US House of Representatives from Kentucky, 4th District.
* March 4 – Joshua Jewett left office as US House of Representatives from Kentucky, 5th District.
* March 4 – John Milton Elliot left office as US House of Representatives from Kentucky, 6th District.
* March 4 – Humphrey Marshall left office as US House of Representatives from Kentucky, 7th District.
* March 4 – James Brown Clay left office as US House of Representatives from Kentucky, 8th District.
* March 4 – John C. Mason left office as US House of Representatives from Kentucky, 9th District.
* March 4 – Lazarus W. Powell entered office as US Senator from Kentucky.
* March 4 – Francis Bristow entered office as US House of Representatives from Kentucky, 3rd District.
* March 4 – William Clayton Anderson entered office as US House of Representatives from Kentucky, 4th District.
* March 4 – Green Adams entered office as US House of Representatives from Kentucky, 6th District.
* March 4 – Robert Mallory entered office as US House of Representatives from Kentucky, 7th District.
* March 4 – William E. Simms entered office as US House of Representatives from Kentucky, 8th District.
* March 4 – Laban T. Moore entered office as US House of Representatives from Kentucky, 9th District.
* April 13 – Henry Tureman Allen born.
* April 14 – George M. Bibb died, aged 82.
* April 18 – Charles H. Parrish born.
* April 21 – Joseph Bentley Bennett born.
* April 26 – James D. Porter died, aged 47.
* May 6 – Joseph B. Smith died, aged 35.
* June 27 – Mildred J. Hill born.
* August 30 – Charles S. Morehead left office as Governor of Kentucky.
* August 30 – Beriah Magoffin entered office as 21st Governor of Kentucky.
* September 22 – Mathilde Brundage born.
* October 29 – John Reccius born.
* November 17 – Linn Boyd died, aged 59.
* November 18 – Ninian Edwards Gray died, aged ~52.