Legendary Pokémon's

1. Articuno - Found in the Kanto region, usually residing in icy and mountainous areas. In the anime, it is encountered in the Orange Islands and in the Kanto region.
2. Zapdos - Found in the Kanto region, usually residing in thunderous areas. In the anime, it is encountered in the Orange Islands and in the Kanto region.
3. Moltres - Found in the Kanto region, usually residing in volcanic and fiery areas. In the anime, it is encountered in the Orange Islands and in the Kanto region.
4. Mewtwo - Created in the Kanto region by Team Rocket in the anime, and then escaped to reside on New Island. Later, it was found in the Johto region.
5. Mew - Resides in the Kanto region, but is only obtainable through event distributions in the games. In the anime, it is encountered in the Kanto region.
6. Raikou - Roams the Johto region and is difficult to find. In the anime, it is seen in the Johto region and encountered by protagonist Ash Ketchum.
7. Entei - Roams the Johto region and is difficult to find. In the anime, it is seen in the Johto region and encountered by protagonist Ash Ketchum.
8. Suicune - Roams the Johto region and is difficult to find. In the anime, it is seen in the Johto region and encountered by protagonist Ash Ketchum.
9. Lugia - Resides in the Whirl Islands in the Johto region. In the anime, it is encountered in the Johto region and plays a significant role in the movie "The Power of One."
10. Ho-Oh - Resides in the Johto region and is said to appear only to those with pure hearts. In the anime, it is encountered in the Johto region and plays a significant role in the first episode of the anime.
11. Celebi - Resides in the Johto region, in the Ilex Forest. In the anime, it is encountered in the Johto region and plays a significant role in the movie "Celebi: Voice of the Forest."
12. Regirock - Resides in the Hoenn region, in the Desert Ruins. In the anime, it is encountered in the Hoenn region.
13. Regice - Resides in the Hoenn region, in the Island Cave. In the anime, it is encountered in the Hoenn region.
14. Registeel - Resides in the Hoenn region, in the Ancient Tomb. In the anime, it is encountered in the Hoenn region.
15. Latias - Resides in the Hoenn region and can disguise itself as a human. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Pokémon Heroes."
16. Latios - Resides in the Hoenn region and can disguise itself as a human. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Pokémon Heroes."
17. Kyogre - Resides in the Hoenn region, in the Cave of Origin. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Pokémon: Destiny Deoxys."
18. Groudon - Resides in the Hoenn region, in the Cave of Origin. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Pokémon: Jirachi Wish
19. Rayquaza - Resides in the Hoenn region, in the Sky Pillar. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Destiny Deoxys."
20. Jirachi - Resides in the Hoenn region and is only awakened every 1000 years. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Pokémon: Jirachi Wish Maker."
21. Deoxys - Resides in the Hoenn region and is a DNA Pokemon that can change forms. In the anime, it is encountered in the Hoenn region and plays a significant role in the movie "Destiny Deoxys."
22. Uxie - Resides in the Sinnoh region, in Lake Acuity. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
23. Mesprit - Resides in the Sinnoh region, in Lake Verity. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
24. Azelf - Resides in the Sinnoh region, in Lake Valor. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
25. Dialga - Resides in the Sinnoh region and controls time. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
26. Palkia - Resides in the Sinnoh region and controls space. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
27. Giratina - Resides in the Distortion World and can control dimensions. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "Giratina and the Sky Warrior."
28. Cresselia - Resides in the Sinnoh region and is the Lunar Pokémon. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "The Rise of Darkrai."
29. Heatran - Resides in the Sinnoh region, in the Stark Mountain. In the anime, it is encountered in the Sinnoh region.
30. Regigigas - Resides in the Sinnoh region and is known as the Colossal Pokémon. In the anime, it is encountered in the Sinnoh region.
31. Shaymin - Resides in the Sinnoh region and is known as the Gratitude Pokémon. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "Giratina and the Sky Warrior."
32. Arceus - Resides in the Sinnoh region and is known as the Alpha Pokémon. In the anime, it is encountered in the Sinnoh region and plays a significant role in the movie "Arceus and the Jewel of Life."
33. Reshiram - Resides in the Unova region and is known as the Vast White Pokémon. In the anime, it is encountered in the Unova region and plays a significant role in the movie "Pokémon the Movie: White - Victini and Zekrom."
34. Zekrom - Resides in the Unova region and is known as the Deep Black Pokémon. In the anime, it is encountered in the Unova region and plays a significant role in the movie "Pokémon the Movie: Black - Victini and Reshiram."
35. Kyurem - Resides in the Unova region and is known as the Boundary Pokémon. It has two alternate forms, Black Kyurem and White Kyurem. In the anime, it is encountered in the Unova region and plays a significant role in the movie "Pokémon the Movie: Kyurem vs. the Sword of Justice."
36. Keldeo - Resides in the Unova region and is known as the Colt Pokémon. In the anime, it is encountered in the Unova region and plays a significant role in the movie "Pokémon the Movie: Kyurem vs. the Sword of Justice."
37. Xerneas - Resides in the Kalos region and is known as the Life Pokémon. In the anime, it is encountered in the Kalos region and plays a significant role in the movie "Pokémon the Movie: Diancie and the Cocoon of Destruction."
38. Yveltal - Resides in the Kalos region and is known as the Destruction Pokémon. In the anime, it is encountered in the Kalos region and plays a significant role in the movie "Pokémon the Movie: Diancie and the Cocoon of Destruction."
39. Zygarde - Resides in the Kalos region and is known as the Order Pokémon. It has three alternate forms, 10% Forme, 50% Forme, and Complete Forme. In the anime, it is encountered in the Kalos region and plays a significant role in the series "Pokémon the Series: XYZ."
40. Solgaleo - Resides in the Alola region and is known as the Sunne Pokémon. In the anime, it is encountered in the Alola region and plays a significant role in the series "Pokémon the Series: Sun and Moon."
41. Lunala - Resides in the Alola region and is known as the Moone Pokémon. In the anime, it is encountered in the Alola region and plays a significant role in the series "Pokémon the Series: Sun and Moon."
42. Necrozma - Resides in the Alola region and is known as the Prism Pokémon. It has two alternate forms, Dusk Mane Necrozma and Dawn Wings Necrozma. In the anime, it is encountered in the Alola region and plays a significant role in the series "Pokémon the Series: Sun and Moon."
43. Zacian - Resides in the Galar region and is known as the Warrior Pokémon. It has two alternate forms, Hero of Many Battles Zacian and Crowned Zacian. In the anime, it is encountered in the Galar region and plays a significant role in the series "Pokémon Journeys: The Series."
44. Zamazenta - Resides in the Galar region and is known as the Warrior Pokémon. It has two alternate forms, Hero of Many Battles Zamazenta and Crowned Zamazenta. In the anime, it is encountered in the Galar region and plays a significant role in the series "Pokémon Journeys: The Series."
45. Eternatus - Resides in the Galar region and is known as the Gigantic Pokémon. In the anime, it is encountered in the Galar region and plays a significant role in the series "Pokémon Journeys: The Series."
46. Calyrex - Resides in the Galar region and is known as the King Pokémon. It has two alternate forms, Ice Rider Calyrex and Shadow Rider Calyrex. In the anime, it is encountered in the Galar region and plays a significant role in the series "Pokémon Journeys: The Series."

*Note that the sightings of the legendary Pokémon can vary between different sources of the anime, such as movies, episodes, and specials, and may not be comprehensive. Additionally, some legendary Pokémon may not have appeared in the anime yet.*