Alex Power

* Angel - *Enemy*: Power Pack fight with Angel when he has become Death (X-Factor #25)
* Annihilus - *Enemy:* they are antagonists in the FF Family Freakout storyline
* Apocalypse - *Enemy*: Power Pack discuss Apocalypse with members of X-Factor (XF #25)
* Artie Maddicks - they know each other after the Mutant Massacre (X-Factor An. #2) and meet in Central Park (X-Factor An. #2), later they are both members of Future Foundation
* Beast - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2)
* Ben Reilly - Ben works together with New Warriors
* Captain Britain - Alex gets the help of Excalibur to free his family (Excalibur #29)
* Caliban - Power Pack save Caliban from the Mutant Massacre (#27)
* Callisto - they have been allies (PP #11-12, X-Men #195)
* Cloak - they become friends when bringing justice to the drug lord Diangelo (Power Pack #6-8)
* Collector - Marrina tells Alex about The Collector when they meet on Coney Island (Power Pack #9)
* Cyclops - they join forces in the tunnels during the Mutant Massacre (Power Pack #27), against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Dagger - they become friends when bringing justice to the drug lord Diangelo (Power Pack #6-8), later briefly in New Warriors together (until #51)
* Darkhawk - briefly in New Warriors together (until #51)
* Doctor Doom - *Enemy:* they are antagonists in the FF Family Freakout storyline
* Dragon Man - they joined forces in defeating the drug lord Diangelo (Power Pack #7-8), later members of Future Foundation
* Edwin Jarvis - Alex hears Franklin Richards talk of Jarvis (Power Pack #27)
* Fandral - Power Pack and Warriors 3 combine forces to defeat Bogeyman in Central Park (PP #15)
* Firestar - in New Warriors together
* Franklin Richards - Franklin joins the Power Pack and lives with them, and later Alex lives with FF
* Hogun - Power Pack and Warriors 3 combine forces to defeat Bogeyman in Central Park (PP #15)
* Human Torch - the PP kids first discuss the Fantastic Four at home (PP #5), later both are part of the Fantastic Four extended family
* Human Torch (Android) - Hammond is caretaker of the Future Foundation kids for SHIELD (Fantastic Four #5.5)
* Iceman - they join forces in the tunnels during the Mutant Massacre (Power Pack #27) and against Quicksilver and Maximus (X-Factor An. #2)
* Jack Power - sibling
* Jean Grey - they join forces in the tunnels during the Mutant Massacre (Power Pack #27), against Quicksilver and Maximus (X-Factor An. #2) and Pestilence (XF # 25)
* Julie Power - sibling
* Katie Power - sibling. Nickname: "Katie Baby" (#Power Pack #9), "Baby" (#25)
* Leech - they became friends when Power Pack were captured (X-Men #195), also saves Leech from the Mutant Massacre (PP #27), later they are members of Future Foundation
* Luna Maximoff - they are members of Future Foundation
* Marvel Boy - in New Warriors together
* Maximus - they are antagonists in the FF Family Freakout storyline
* Medusa - both live in the Baxter Building as part of the Fantastic Four extended family
* Meggan - Alex gets the help of Excalibur to free his family (Excalibur #29)
* Namorita - briefly in New Warriors together (until #51)
* Nightcrawler - they have allied early on, and later Alex gets the help of Excalibur to free his family (Excalibur #29)
* Nightmare - *Enemy:* they do battle in Excalibur #29
* Night Thrasher - briefly in New Warriors together (until #51)
* Nova (Richard Rider) - briefly in New Warriors together (until #51)
* Quicksilver - they fight in Central Park as Quicksilver kidnaps Franklin Richards (X-Factor An. #2)
* Rachel Summers - X-Men and Power Pack are friends (e.g. X-Men #195), later Alex gets the help of Excalibur to free his family (Excalibur #29)
* Rage - briefly in New Warriors together (until #51)
* Reed Richards - the Power Pack kids first discuss the Fantastic Four at home (PP #5), and Franklin early on tells PP about his parents, later both become part of the Fantastic Four extended family
* Rogue - X-Men and Power Pack are friends (e.g. X-Men #195)
* Sabretooth - *Enemy:* they battle during the Mutant Massacre (Power Pack #27)
* Scott Lang - both live in the Baxter Building as part of the Fantastic Four extended family
* Shadowcat - X-Men and Power Pack are friends (e.g. X-Men #195)
* She-Hulk - both live in the Baxter Building as part of the Fantastic Four extended family
* Silhouette - briefly in New Warriors together (until #51)
* Speedball - in New Warriors together (Speedball impostor until #51). Nickname: "Spazball" (#67)
* Spider-Man - the kids first talk of Spider-Man at home (Power Pack #5), then become allies (#6)
* Sub-Mariner - the Future Foundation kids watch Namor guide them in the deep sea (Fantastic Four #5.3)
* Susan Richards - the Power Pack kids first discuss the Fantastic Four at home (PP #5), and Franklin early on tells PP about his parents, later both become part of the Fantastic Four extended family
* The Thing - the Power Pack kids first discuss the Fantastic Four at home (PP #5), later both become part of the Fantastic Four extended family
* The Watcher - the entire extended Fantastic Four circus invades Uatu's Moon dwelling (FF #2.13)
* Thor - The Warriors Three talk of Thor after they have met in Central Park (Power Pack #15)
* Valeria Richards - both become part of the Fantastic Four extended family
* Volstagg - Power Pack and Warriors 3 combine forces to defeat Bogeyman in Central Park (PP #15)
* Wolverine - X-Men and Power Pack are friends (e.g. X-Men #195)