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Q: Validate Date in the request body I have a request body have date field and I want to validate the input of the date and return error code 400 BadRequest if the format is wrong. If I use the JsonFormat then it throws error 500: @JsonFormat(shape=JsonFormat.Shape.STRING, pattern="yyyy-MM-dd") private Date dateAt; So I changed the field to String and then parse and throw BadRequest format everywhere using the getDate() I am not really satisfied with this approach. Is there any other elegant way to achieve this validation? I think I will accept error 500 from JSON formatter and skip my custom exception. A: Since Java 8, you should avoid using Date. Java 8 brought an entirely new date and time API. According to your question, a suitable replacement for Date would be LocalDate, which is expected to be in the format yyyy-MM-dd. Jackson has a module supporting the new date and time API and an exception will be thrown if the date is not in the correct format. When serializing, you want to make sure the WRITE_DATES_AS_TIMESTAMPS feature is disabled, so the values will be written according to the ISO 8601 format.
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LG Cell Phone LG cell phones are the third most popular brand of cell phones in the world. But did you know that LG is actually one of the largest conglomerates in the world and that they make everything from LG cell phones to televisions to home appliances? LG Electronics, the maker of LG cell phones, is actually a subsidiary of LG Group, a company based in Yeouido, Seoul, South Korea. This huge conglomerate has 75 subsidiaries worldwide, that manufacture a wealth of personal, electronic and household goods. LG Electronics is also the current owner of Zenith Electronics. Zenith was a popular and well-known American electronics manufacturer headquartered out of Lincoln, Illinois before being bought by LG in part in 1995 and in whole by 1999. Though the Zenith brand still exists, they are now sold and serviced by LG Electronics. Aside from brining the LG cell phone to prominence as the third best selling cell phone brand, LG is also the world’s largest plasma panel manufacturer. Its affiliate LG Display, (of which it owns the majority share) is one of the largest manufacturers of liquid crystal displays. It’s no wonder that the LG logo is ubiquitous when visiting an electronics store or even just a department store. This giant electronics conglomerate has their corporate fingers in many different consumer electronics pies. In 2008, LG even announced that they were diving into the green and sustainability sphere by buying a major share in a company that creates solar panels. LG is the product of the merger of two South Korean companies during the 1950′s. The two companies, named “Lucky” and “GoldStar,” contributed to the “LG” acronym. Contrary to popular consensus and LG’s marketing, LG does not stand for “Life’s good.” Instead, that is an example of a “backronym,” (i.e. a phrase constructed, jokingly or otherwise, in order to imbue a word or set of letters with meaning after the fact.) LG cell phones came to prominence partly due in part to their small size and similarly low price. Most LG phones come in a clam shell format, where part of the phone covers the keys when the phone isn’t in use. Many users liked these phones because of their aesthetically pleasing look and the fact that they were easy to accessorize with covers, cases, charms, etc. It is perhaps for that reason that LG has a huge fan following, with many people professing brand loyalty. LG cell phones have, of course, jumped onto the G3 technology bandwagon. The LG Incite is a touch screen smart phone that still embraces the signature rounded LG aesthetic. This LG cell phone features all the G3 standards – touch screen, MP3 player, camera, WiFi, web navigation, Microsoft Office, Bluetooth technology, and the ability to add games, music, pictures, and various applications. One of its more interesting features is the vibration feedback included with the 3 inch touch screen. This feature is meant to emulate the feel of pushing a button, and users, who will now feel vibrations after pushing a button, will be spared tapping the screen over and over again wondering if the touch “took” or if the phone is just being slow. If you have ever jammed up your phone, iPod, or even ATM machine due to just such a malfunction, you will surely appreciate this thoughtful, inventive little piece of convenience technology. Whether in clam shell format or embracing the newest G3 technology, LG cell phones have risen to the top of the cell phone market. Eager LG fanatics out there are eagerly awaiting the new technologies that LG’s research and development team will come up with next. This LG Cell Phone Review is Written/Updated on Oct 2nd, 2009 and filed under Consumer Electronics. Both comments and pings are currently closed.
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Q: How should I sub class a class that constructs its objects primarily using Static methods I have a class, that takes a lot of esoteric parameters to construct an object. I didn't write the code and frankly speaking, I don't understand completely, all of it's nuances. There is a valueOf(String) method of this class, that is primarily used to construct objects of this class and it also does fairly complex computation to construct the object. I pass an array of objects of this class into a report generation package that calls the toString() method of each of these objects and constructs a header. I need to override the toString() method to get rid of some extra stuff that it returns, so that my headers look clean. What would be the best way to do this. I thought of subclassing this class, but even that is proving to be a bit painful, since I have to replicate valueOf() method for the subclass. A: I need to override the toString() method to get rid of some extra stuff This approach seems to be the main issue. When I read this sentence, it gave me an immediate warning sign, since you are trying to change the behaviour of a class in an incompatible fashion by using inheritance. This can easily become a violation of the LSP and can cause a lot of unforeseen issues. Instead of (ab)using inheritance, a better way might be to create something like a proxy or wrapper object for each of the objects in the returned array, which can be done after the construction of the original objects, there is no need to tweak the construction code itself. The wrapper class implements toString in the desired fashion, using calls to toString of the wrapped object, if necessary. It can also implement any other method required by your report generator in a similar fashion. Then pass the resulting array of wrapped objects into the report generation package. Note this solution is independent from the construction process, so it does not actually matter if there are mainly static methods involved or not. A: You can't. The usage of static methods makes your code, well, static. I would encourage you to create a builder for this class which calls protected but non-static methods. From there, you can easily extend that class and override the methods as you need to. You don't have to eliminate the static methods outright if you think there are those who use them. Instead consider deprecating them and in your following release, you can remove them then. Good luck to you!
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Hurricane shutters comprise a major portion of the hurricane protection industry. Hurricane shutters can be affixed to a structure in several different ways depending on the particular requirements of each job combined with the published test results of each individual shutter. Shutters can be affixed directly to the substraight or installed into various tracks (i.e. f track, u headers studded angle etc). In many cases, a sidewalk bolt is the preferred bolt be cause of its low head profile and large diameter head. The combination Sidewalk Bolt is the preferred bolt because it gives the advantage of using a phillips or slotted drive to install and remove these screws. In most cases, the sidewalk bolts need to be removed or loosened to hang the hurricane shutters. Combination sidewalk bolts are constructed with a large diameter and low profile head allowing the screw to be used on a floor or on a wall without being a hazard to the public. The large diameter head is usually preferred because the there is a larger portion of the fastener holding the shutters or tracks in place. Because of the thin profile of the head of the bolt, it has only been possible to construct these bolts with a slotted head. While advantages are obtained when bolts are provided with a head, particularly in the ease of use, it has not been possible to provide a combination sidewalk bolts with such a head following generally accepted design principles. In particular, the depth of the recess of the Phillips drive which is required for the Phillips drive exceeds accepted limits in comparison to the height of the bolt head. A need therefore has existed for a combination sidewalk bolt which is provided with a Phillips drive. The need for a combination sidewalk bolt constructed with a Phillips head has been satisfied by the present invention wherein in one aspect of the invention a combination sidewalk bolt is provided with a head portion having a threaded shaft portion extending perpendicularly outward from a first side. A Phillips head recess well is formed in a second side of said head portion wherein the depth of the recess well is at least eight tenths of the width between the first side and second side of the head portion. In another aspect of the invention the Phillips head recess well extends into the shaft of the bolt.
{ "pile_set_name": "USPTO Backgrounds" }
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Susan Fales-Hill Susan Fales-Hill (born August 15, 1962) is an American television producer, author, screenwriter and an advocate for the arts and education. Early years Fales-Hill is the daughter of Haitian-American actress Josephine Premice, who was well known for her work on the Broadway stage and to Timothy Fales, an American stockbroker, whose ancestors were pilgrims arriving in the Mayflower from England in 1620. She attended the Lycée Français de New York and graduated from Harvard University with a degree in literature and history. Career Fales-Hill was a writer for The Cosby Show and the lead writer and producer for A Different World. Personal life Fales-Hill married Aaron Hill, a New York banker, in 1997. Their daughter Bristol was born in 2003. In addition to her native English, Fales-Hill is able to speak French, Italian, Spanish, and speaks some Haitian Creole. References External links Category:Living people Category:1962 births Category:American people of English descent Category:American people of Haitian descent Category:Lycée Français de New York alumni Category:Harvard University alumni Category:American television executives Category:Television producers from New York City Category:American expatriates in Italy Category:Screenwriters from New York (state)
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Influence of age and nephrectomy on metastatic patterns in Wilms' tumors. Data from 194 autopsy cases of Wilms' tumor were analyzed statistically to investigate the mode of dissemination by classifying them according to the number of organs involved in metastasis, age and history of nephrectomy. Metastasis-free cases were more frequent in cases under two years of age, in bilateral cases, and in non-nephrectomized cases. The frequencies of metastasis to various organs were essentially similar among the various age groups, except those to the contralateral kidney and intestines in cases under two years of age, which were significantly more frequent. Nephrectomized cases showed a significantly higher incidence of metastasis to the peritoneum than non-nephrectomized cases. In cases with metastasis to one organ, metastasis to the lungs, lymph nodes and liver showed low frequencies (17%, 13% and 17%, respectively), but that to the peritoneum showed a rather high frequency (21%). Radiation therapy for the peritoneum after nephrectomy is recommended.
{ "pile_set_name": "PubMed Abstracts" }
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cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I). We have isolated and sequenced cDNA clones of bovine and murine p11 mRNAs. The nonpolyadenylated mRNAs are predicted to be 614 and 600 nucleotides, respectively. The p11 mRNAs both contain a 291 nucleotide open reading frame, preceded by a 5'-untranslated region of 73 nucleotides in bovine p11 mRNA and of 68 nucleotides in murine p11 mRNA. The deduced bovine p11 amino acid sequence is identical to the previously published partial bovine and complete porcine p11 protein sequence except for an additional COOH-terminal lysine residue. The bovine and murine p11 proteins are 92% homologous, whereas at the nucleotide level the conservation is 89% in the coding region and 75% in the 3'-untranslated region. Southern analysis of murine genomic DNA detected a single p11 gene, less than 10 kilobase pairs in size, containing as many as three introns. The p11 gene has been assigned to mouse chromosome 3 by analysis of interspecific hybrid cell panels and recombinant inbred mouse strains. The p11 gene is closely linked to the Xmmv-65 endogenous leukemia virus env gene and the guanylate binding protein-1 gene. Northern analyses of RNAs from mouse tissues and cell lines indicated that p11 mRNA levels vary widely. They are very low in liver, heart, and testes, moderate in brain, spleen, and thymus, and high in kidney, intestine, and lung. Analysis of the same RNA samples for p36 mRNA levels showed that expression of p11 and p36 mRNAs is not always coordinated. Brain and the mouse embryonal carcinoma cell line F9 contain moderate to high levels of p11 mRNA with very low levels of p36 mRNA. Sequence homology between p11 and the S100 proteins, and the serum-induced 2A9 gene product, as well as possible functions of p11 are discussed.
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Q: How to make ajax postback in form with list of check boxes I dynamically draw checkboxes in my form: @using (Html.BeginForm("Action", "Controller", FormMethod.Post, new { id="itemsList"})) { foreach (var lt in Model.MyList) { <li> <label id="label"> <input value="@lt.itemId" type="checkbox" /> @lt.Title</label> </li> } } JQuery function: $(document).ready(function () { $('#itemsList').ajaxForm({ success: Saved, error: HandleError }); }); ... But my action is not fired. Am I doing something wrong here? I am expecting that when I check checkbox make server call. A: I am expecting that when I check checkbox make server call. You should not expect that unless you've written handler for checkbox change $(document).ready(function () { $('#itemsList').ajaxForm({ success: Saved, error: HandleError }); $(':checkbox').change(function(){ $('#itemsList').submit(); }); });
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Nearly three months after a reauthorization deadline for the Children’s Health Insurance Program (CHIP) came and went, Congress voted on Thursday to provide piecemeal funding for the program before they left for the holidays. But the legislation passed did little to resolve the burgeoning crisis. And some state officials say that they are still planning to proceed as if the health care program for poor children will be fully out of funds in the near future. The bill that passed, which was tucked into a larger government funding measure, provided an additional $2.85 billion for CHIP as a means of propping up the program until the end of March 2018. Additionally, the bill extended a previous measure allowing the Centers for Medicare and Medicaid Services (CMS) to free up redistribution funds for states in dire need. The measure prevented a child health care tragedy from unfolding over the holidays. The Georgetown University Health Policy Institute had published a report on Wednesday which said that absent any kind of immediate funding from Congress, some 1.9 million children were posed to lose coverage in January, with another 1 million at risk by the end of February. But, in all, the legislation was a far cry from the five-year reauthorization that advocates and many lawmakers said Congress needs to pass. And even though states and advocates were happy to see a small-scale funding plan, there was immediate concern that the patchwork fix left administrators in an unstable position and families confused as to whether their coverage will continue. David Dearborn, communications director at the Connecticut Department of Social Services told The Daily Beast that the state was still reviewing financial options. Officials have warned that the state’s program, known as Husky B, which covers some 17,000 kids and teenagers, will end on Jan. 31 unless Congress reauthorizes funding. And, as of Thursday afternoon, prior to the vote, the Department of Social Services had no immediate plans to change their new-enrollment cutoff date of December 23, just two days away. “I work with the state officials trying to manage this program and for them this is chaotic,” Maureen Hensley-Quinn, Senior Program Director for the National Academy for State Health Policy told The Daily Beast. In Colorado, things were only slightly more certain. Late last month , the Colorado Department of Health Care Policy and Financing had sent a notice to families informing them that the program could end by the end of January absent a funding fix from Congress. Now, officials are waiting to determine next steps both from Congress and an independent request from Gov. John Hickenlooper (D) for more funding from the state’s Joint Budget Committee. State officials don’t want to send out a letter to CHIP enrollees that they may lose coverage only have to then backtrack. “You don’t want to be following up next week and saying “You’re fine, we don’t mean it. We want to be able to give people clear direction,” Luke Clarke, Director of Communications for Connect for Health Colorado told The Daily Beast on Thursday. “Anything that keeps the program going is better than nothing. But it needs to come fast because the families have to be notified.” For other states, like Alabama, the CHIP crisis is far more immediate and the short-term aid passed by Congress could very well prove helpful in pushing some difficult steps, such as sending out disenrollment letters to families right after Christmas. But even then, Congress’ intervention was a mere blip on the road to larger potential ruin. Alabama had planned on sending such notices on December 28 informing families that they would be freezing enrollment on January 1 and disenrolling children by February 1. State officials said they will likely now move back that timeline but they are pressed still to figure out next steps. “I talked with somebody in Alabama and if this passes, they would delay their January 1 enrollment freeze,” Hensley-Quinn told The Daily Beast. But she acknowledged, “That’s sort of kicking the can down the road a bit.” Cathy Caldwell, the director of the Bureau of Children’s Health Insurance at the Alabama Department of Public Health, did not immediately respond to a request for comment. Virginia's Department of Medical Assistance Services (DMAS) sent a letter to families on Dec. 12 informing them that the state’s program could be shut down on Jan. 31. But with this new influx of money, they're hopeful they can make it through the month. “The additional funding congress has provided will allow Virginia to keep children and pregnant women covered through January and maybe longer,” Nancy Malczewski, Public Information Officer for DMAS told The Daily Beast. “We will have to wait and hear from CMS how much of this funding will come to Virginia before we can determine how long we can continue to operate FAMIS. We hope to have that answer shortly after Christmas.” Among the problems states face even in the wake of Congress’ short-term CHIP fix is that it costs money and requires resources to develop contingency plans. Relying on a five-year funding window allows officials to easily budget. Working with funding on a month-to-month basis is exceptionally hard. Additionally, most states attempt to inform enrollees of impending outcomes with at least 30 days notice. And sending those notices isn’t free. In Colorado, Clarke said the cost of informing enrollees could be about $484,000. So while Congress stopped a major problem from becoming an abject crisis on Thursday, it did little to give states actual relief. “They’re going to continue to put states in this terrible position,” Joan Alker, Executive Director of Georgetown University Center for Children and Families told The Daily Beast. “They’re not giving families the piece of mind they need going into the holidays that their child’s health coverage is secure. And that’s what they should be doing.”
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Ask HN: Hackathon at Launch? - jasonmcalacanis Should we host a Hackathon at LAUNCH this week?<p>We have the San Francisco Design Concourse from Monday until Thursday night.<p>Q: What makes for a good hackathon? Q: What would we need to host it? ====== DTrejo Just semi-hosted a hackathon recently. Key elements: - good desks / places to sit and code - reliable internet - free dinner, midnight and/or 3am food - healthy food in addition to junky food - some like energy drinks - don't have people pitch their ideas - have an official wiki for people to post their team+idea - tell contestants your judging criteria before the hackathon starts (and make sure judges know it) - keep presentations speedy, with a gong to keep people honest (<5mins for final demos) - have a nice big central room for everyone to code in (don't spread people out across the building) - don't require judges to give feedback after each demo Some of these are lessons learned from the New England College Hackathon (<http://nech2011.com/>). ~~~ thegoleffect +1 for reliable internet. One dinky router is not enough to satisfy 200 hackers. I've been to half a dozen with internet issues and it destroys productivity. Even with iPhone tethering, if we had 200 tetherers the cross- interference would make it just as bad. In addition to internet though, do not forget adequate power - electricity. ~~~ petercooper +2. At a hack day I was at recently, it took the guy next to me 10 hours to install Git (from source), Ruby (from source), download some gems and get Rails running because the bandwidth was so in and out. His bad for not coming with a properly set up machine, but still.. Good Internet can undo a lot of miseries. ------ geoffclapp First, the answer is an absolute yes. Hackathon would be great. I would rather do that all night the first night than go to a party (realizing, of course I just posted this on the internet, and now look amazingly lame). I think the two most important things are internet access (which you have covered) and good working space - for example, folding tables, chairs, and powerstrips are more than fine (in fact, we can bring our own of the later), but places we can sit next to each other will be key. And energy drinks. ------ geoffclapp @Jason - might be good to take a look at the comments/frustrations on hackathons in this thread to get some ideas as well of what people liked/didn't like. <http://news.ycombinator.com/item?id=2240226> ------ jasonmcalacanis Maybe we can put the best three on stage? Angel invest in them? ~~~ il I was going to write something snarky about the bubble here, but after thinking about it, a half baked product of an all night hackathon getting angel investment is par for the course. Definitely put the top ones on stage in front of investors, and, if you can, give every participant some kind of freebie(free pass to the conference?). The people who participate in hackathons are exactly who you want to be putting in front of investors as much as possible. ~~~ jasonmcalacanis Yeah, a free pass wouldn't be a problem for some folks. we already gave 50 developers on HN free tickets, and Mahalo's 20 developers are coming. :-) ------ staunch Sounds awesome. I don't think anything is necessary beyond internets. I'd probably participate. Letting the best three on stage would be awesome as long as you ensure the code was written _during_ the hackathon (people tend to cheat a bit on this I think). ------ stefanobernardi I recently co-organized <http://hackitaly.org> and it was a great success mainly due to: \- focus on a set of predefined APIs, which key developers from the relating companies present in the room \- a shitload of prizes from those companies for the best projects (each company decided who to give the prizes to) \- free breakfast/lunch/dinner \- redbull \- huge room with tables of 6 people \- no ideas pitching, just coding ------ daimyoyo I think that Launch wouldn't be complete without a hackathon. What you'll need is enough Internet connections to let everyone who wants to get in have their own, and LOTS of pizza and energy drinks. Perhaps you could persuade a local pizzeria to throw in pies for a sponshorhip. Also, the winning team should be able to present their idea on stage. Do this and you'll have a great hackathon in addition to a great event. ~~~ jasonmcalacanis We have 400MBIT down and 40 mBIT up and 250 ethernet cables being run.... is that enough? :-) Considering we are spending $100k on the internet connections, I think we can afford to pick up the pizza tab no problem. :-) ~~~ daimyoyo It's not a question of being able to afford it(I assume you could give everyone who attends the entire conference a pizza and still have $ left over) it's what would be most effective for the most people. If you get a local place to do it for you you'll not only save on the cost of pizzas(more profits to invest in the winner of the event) you'll give a local place some much needed attention. Plus, since a lot of people who will go to the hackathon already live in the area, they'll get quite a few new customers as well. And if that's not a win-win, I don't know what is. ------ allanscu \-- Reliable Internet is important: I was at SuperHappyDevHouse 42 in San Jose last weekend and the wireless was slow... really.. slow \-- Energy Drinks: Rockstar and Red Bull! \-- Ice Breakers: It's great to have a bunch of people there, but it would be so much better if there was a timeout in the main room and we did a simple "get to know you" ------ keesj I'm in! Be sure to provide a way for people to team up in advance since a lot of people might come alone to the conference. (team up designers w/ developers) ------ keesj By the way, don't make it too long and give people enough time to rest/freshen up before the actual conference ;)
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Commit Media Commit Media is a socially entrepreneurial company that utilizes entertainment to advance the missions of non-profits and philanthropic organizations. The company also works with celebrities and public figures who have an authentic connection with a cause and want to achieve lasting impact. The CEO of Commit Media is Paul Katz, a long-time entertainment industry executive and two-time Grammy nominee. Founding Commit Media was founded in 2005 by Paul Katz with offices based in New York City. The company now employs consultants from around the world for a variety of professional tasks. Services Commit focuses on celebrity-to-cause matching, entertainment consulting, marketing and earned income generation. Utilizing music, film, television, print, online, mobile and social media, Commit Media supports causes ranging from the arts to education, the environment, health, children, human rights, poverty, animal welfare, and international development. Past projects American Dental Association Commit Media advised and facilitated the "Give Kids A Smile" campaign through cementing celebrity sponsorships and executive producing a PSA featuring three-time MVP Major League Baseball player Albert Pujols. American Diabetes Association Commit Media provided celebrity matching and marketing for American Diabetes Association's "I Decide to Fight Diabetes," a multi-year campaign. Celebrities involved in the campaign included Patti LaBelle, Sherri Shepherd, Maria Menounos, Donna Richardson Joyner, Mama Love, and Donnie McClurkin. The company also added a mobile component to the campaign and generally assisted with marketing. TJ Martell Foundation Organized and produced "Between the Covers", a benefit CD to support the work of the T.J. Martell Foundation, which supports research for leukemia, cancer and AIDS. Artists on the compilation included Eric Clapton, Madonna, Alicia Keys, Sheryl Crow, Lenny Kravitz, Norah Jones, Mick Jagger, David Bowie, The Dixie Chicks and Sarah McLachlan. "Between The Covers" was released by Sony BMG in the U.S. and Nettwerk in Canada. VH1 and VH1 Classic aired a "Between the Covers," television special hosted by actor/director Kevin Bacon and his brother Michael. The Bacon Brothers perform their rendition of the Beatles' "If I Needed Someone" on both the VH1 special and the album. The Rosa and Raymond Parks Institute Produced "A Tribute To Mrs. Rosa Parks," a compilation album project, honoring Rosa Parks and commemorating the 40th anniversary of the Montgomery bus boycott. The album was inspired by themes from Parks' book, Quiet Strength, and included award-winning Gospel acts, such as Yolanda Adams, Shirley Caesar, and Fred Hammond & Radical For Christ, to revive public interest in freedom. Mrs. Rosa Parks reads extracts from "Quiet Strength" on the album and also appears in the promotional video of the lead track, "(Something Inside) So Strong". The sales from the album raised more than $300,000 for the Rosa and Raymond Parks Institute for Self Development Environmental Defense Fund Brokered a relationship between the Environmental Defense Fund and Gibson. An initial collaboration took place at the Country Music Association Festival in Nashville, where Gibson hosted a tent on global warming. Alongside visual depictions of the impacts of climate change, Gibson displayed its custom Environmental Defense Fund-themed guitar. Commit Media also produced the film, Discovering Hetch Hetchy for the EDF, about America's first conservation battle which resulted in the loss of a valley in Yosemite National Park. Directed by David Vassar and narrated by Harrison Ford, the film and its PSA won a silver and gold medal respectively for Public Service Video at the Summit Awards, an organization that recognizes and celebrates the creative accomplishments of small and medium sized advertising agencies and other creative groups with annual billings of $25 million or less. The film also won "Best Short" at the 2006 Wild and Scenic Environmental Film Festival and was a finalist in the 2007 Jackson Hole Wildlife Film Festival awards. Selected current projects Rotary International Commit Media has conducted worldwide entertainment strategy for the "End Polio Now" marketing and communications campaign, including celebrity spokespersons for PSAs, media outreach, concert and event production. Commit also executive produced the "Concert to End Polio" with the New York Philharmonic and polio survivor and violinist Itzhak Perlman, which took place in December 2009 and raised six-figures for the cause. In 2011, Commit once again executive produced the second "Concert to End Polio" with the Chicago Symphony Orchestra, Itzhak Perlman and polio survivor and conductor James DePreist. Best Friends Animal Society Commit collaborated with Best Friends on marketing the “Puppies Aren’t Products” campaign. The company organized and produced the PSA associated with the campaign, which featured actress Rachelle Lefevre and has earned over $7.5 million of card rate air time on TV and radio, and over 495 million impressions. Rachelle continued her work with Best Friends by appearing at Oprah’s “Live Your Best Life” walk in May, 2009, walking alongside other Best Friends supporters Neko Case, Emmylou Harris, and Maggie Q. Selected celebrity involvement References Category:Companies established in 2005 Category:Social entrepreneurship Category:Media companies based in New York City
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Tips and suggestions are offered to help you participate in your own care and ensure a safer hospital stay. The French version of this pamphlet 1522, "Priorité aux patients: Patients hospitalisés", is also available. Tips and suggestions are offered to help you participate in your own care and ensure a safer hospital stay. The French version of this pamphlet 1522, "Priorité aux patients: Patients hospitalisés", is also available. Tips and suggestions are offered to help you participate in your own care and ensure a safer hospital visit. The French version of this pamphlet 1521, "Priorité aux patients: Patients externe", is also available. Tips and suggestions are offered to help you participate in your own care and ensure a safer hospital visit. The French version of this pamphlet 1521, "Priorité aux patients: Patients externe", is also available.
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原因は、「いつもより東に偏った太平洋高気圧」と「寒冷渦(かんれいうず)」 本来台風は、太平洋高気圧の縁に沿って進むのですが、今年の太平洋高気圧は日本の東に居座り続けていて、日本付近への張り出しが弱い状態。さらに、大陸からは「寒冷渦」が進んできました。今回、この寒冷渦が西日本の上空に居座ってしまいます。 そこに、台風10号が東日本に接近。寒冷渦の周りを回る反時計回りの風に乗ってしまい、北西の方面へ進む史上初のコースをとり、その結果、史上初の「東北太平洋側からの上陸」の可能性が高まっています。
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Van Jones: ‘The Oldest Terrorist Organization in the U.S. Is Not ISIS, It’s the KKK’ JONES: That’s real leadership. And it’s real leadership on the question of white supremacy but also we need leadership on the question of terrorism. The oldest terrorist organization in the United States is not ISIS. TURNER: That’s right. JONES: It’s the Ku Klux Klan. I mean, you have a terrorist organization who is publicly marching in our streets. I cannot manage imagine a situation — imagine Fort Hood where a Muslim terrorist shot down a bunch of Americans and the president comes out and says, well, there’s violence on many sides. There would have been pandemonium and justifiably so. When you have terrorism, white supremacist terrorism or any other kind, that is the time for clarity. And my problem with this president is he is very, very good at specifically going after his opponents. He goes after the media, over and over and over again. He goes after this politician, that politician. He doesn’t have — I denounced the media a year ago. I don’t have to denounce them today. No, he denounces them several times a day. So there was an opportunity for him to say, listen, I am opposed to terrorism in my country. I’m opposed to white supremacy, and he didn’t do it. And as a result, I’m concerned about these young white guys out there who, is this legitimate, is it not, I don’t know.
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Use of a water-based probiotic to treat common gut pathogens. This work reports the anti-pathogenic effect of a commercially available water-based probiotic suspension, Symprove™, against three commonly encountered infectious organisms; Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA) and Shigella sonnei. An isothermal calorimetric assay was used to the monitor growth of the species individually and in binary combinations, while colony plate counting was used to enumerate viable cell numbers. It was observed that all pathogenic species were faster growing than the probiotic bacteria in Symprove™ after inoculation into growth medium yet in all instances bacterial enumeration at the end of the experiments revealed a significant reduction in the pathogen population compared with the controls. A control population between 108 and 109 CFU/ml was obtained for E. coli and S. sonnei whilst approximately 106 CFU/ml was obtained for MRSA. Upon co-incubation for 48 h, no viable counts were obtained for E. coli; a 4-log reduction was obtained for S. sonnei whilst MRSA numbers were down to less than 10 cells/ml. The results show that Symprove™ has antipathogenic activity against E. coli, S. sonnei and MRSA.
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Dying to Kill (2016) Dying to Kill is a little indie film that received a brief run on Hulu in late 2016, but otherwise, I don’t think it’s available anywhere, so if you want to see it, maybe you can make a flip book of drawings based on my description to get a sense of what it’s like. The film’s promotional materials describe it fairly aptly as “Misery meets The King of Comedy” (the Martin Scorsese film, not the Kings of Comedy concert film, although that wouldn’t be the worst comparison either). It revolves around Shafer Jones (Dwayne Perkins), a standup comic who made a bit of a splash early in his career for having a ton of potential. When that potential didn’t translate into fame and fortune, however, he descended into a rut and has since resigned himself to performing at little clubs for little money telling cheesy, low-brow jokes that pander to the basest desires of the crowds. When one heckler calls him out on his mediocrity, Shafer attacks him, and his career really hits the skids. His manager Jeff, wife Tracy and friend Jenna all encourage him to make a comeback by returning to the more insightful, personal nature of his early material, but when he gets on stage, he chickens out and falls back on the dick and vagina jokes he knows will get a laugh. However, someone’s not laughing. A masked figure is keeping tabs on Shafer and decides to kidnap him and chain him to a stage, forcing him to tell a joke that makes his captor laugh. For every joke that bombs, the kidnapper brings out one of Shafer’s loved ones and kills them in front of him. So, the pressure’s on for him to deliver, or the blood will be on his hands. Like Perkins himself, Dying to Kill has a likability, even if the material doesn’t always land. It’s literate, with a good cast (although Perkins is better at standup than at acting) and has a good-natured, heartfelt script about the value of family and friends and being true to oneself, but given this is supposed to be a horror movie and not the Hallmark Channel, those qualities don’t necessarily translate. As a horror movie, it’s pretty bland and derivative, with a killer who resembles a cut-rate Ghostface from Scream with the voice of Jigsaw from Saw and the modus operandi of Annie Wilkes from Misery. The gore is tame, and the scares are nil. But in its defense, Dying to Kill doesn’t feel like it’s really committed to being a horror movie. It’s just as much a drama, a thriller and a comedy — and while it’s competent at each, it never truly excels in any genre. It actually feels kind of like its target audience is standup comedians, or entertainers in general, encouraging them to tap into their creativity and not “sell out” — which would make its appeal fairly narrow. Although race is not addressed a ton (Shafer is black and his wife is Asian, so there are a few mentions.), his go-to material about eating p*ssy is certainly familiar to those who’ve sat through some hacky black standup acts (think Dave Chappelle’s parody in The Nutty Professor). In the end, Dying to Kill is like a decent standup set; it has a few nice moments where you might find yourself chuckle, but you probably won’t remember it in the long run. Claude claimed selfie defense.“Banana! Oregano! Fandango! Damnit, what’s the safe word?!?”“I am the Ghost of IT Support Past.”Normal ActivityDeath hung up his scythe in favor of something more practical. We use cookies to provide social media options, and to give you a personalized, relevant experience on our website. Continuing to use this site signifies consent. If not, please disable cookies in your browser. Thanks!AgreedRead more
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January/February 2006 Frank Driggs and Chuck HaddixKansas City Jazz: From Ragtime to Bebop Despite the fact that Kansas City has long been recognized as one of the most important centers for jazz, this is the first in-depth history of the subject. Driggs and Haddix have worked on this project individually and collectively for decades, and their book is certain to stand as a reference for readers and researchers alike. The early chapters are problematic: The details that are given are mostly about things like turn-of-the-century brothels, while the fact that Kansas City was one of the most important centers for the incubation of ragtime in the 1890s is barely mentioned. But like a good Basie chart, the narrative gains momentum as it goes along. The authors give an impressive volume of detail about the great KC stylists, moving the spotlight from Bennie Moten, the Blue Devils and Count Basie to Harlan Leonard, Jay McShann and Charlie Parker--while pausing nicely for dozens of lesser figures. The tome culminates with McShann being tracked down on a KC bandstand by draft board officials in 1944 after keeping one step ahead of them for months. 1 Comment Re " this is the first in-depth history of the subject" -- please! Ross Russell's JAZZ STYLE IN KANSAS CITY AND THE SOUTHWEST was published over 30 years earlier, in 1973. Russell also gives, to quote the above review, "an impressive volume of detail about the great KC stylists, moving the spotlight from Bennie Moten, the Blue Devils and Count Basie to Harlan Leonard, Jay McShann and Charlie Parker--while pausing nicely for dozens of lesser figures."
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1. Field of the Invention The present invention relates to the preparation and use of modified zeolite catalyst compositions which are especially suitable for the conversion of substituted aromatic hydrocarbons to provide product mixtures enriched in the para-(or 1,4-) dialkyl substituted benzene isomer. 2. Description of the Prior Art Production of dialkyl substituted benzene compounds via disproportionation, alkylation and/or transalkylation of aromatic hydrocarbons is an important step in a number of commercial chemical manufacturing processes. Such reactions can be carried out over a variety of catalyst materials. Alkylation of aromatic hydrocarbons utilizing crystalline aluminosilicate catalysts has, for example, been described. U.S. Pat. No. 2,904,607 to Mattox refers to alkylation of aromatic hydrocarbons with an olefin in the presence of a crystalline metallic aluminosilicate having uniform openings of about 6 to 15 Angstrom units. U.S. Pat. No. 3,251,897 to Wise describes alkylation of aromatic hydrocarbons in the presence of X or Y-type crystalline aluminosilicate zeolites, specifically such type zeolites wherein the cation is rare earth and/or hydrogen. U.S. Pat. No. 4,086,287 to Kaeding et al discloses the use of ZSM-5 type zeolites as catalysts for the alkylation of aromatic hydrocarbons such as toluene. U.S. Pat. No. 3,751,504 to Keown et al. and U.S. Pat. No. 3,751,506 to Burress describe vapor phase alkylation of aromatic hydrocarbons with olefins, e.g., benzene with ethylene, in the presence of a ZSM-5 type zeolite catalyst. The disproportionation of aromatic hydrocarbons in the presence of zeolite catalysts has been described by Grandio et al in the Oil and Gas Journal, Vol. 69, No. 48 (1971), U.S. Pat. Nos. 3,126,422; 3,413,374, 3,598,878; 3,598,879 and 3,607,961 show vapor-phase disproportionation of toluene over various catalysts. In many of these prior art processes, the dialkylbenzene product produced contains more of the 1,3-isomer than either of the other two isomers. In the conventional methylation of toluene to form xylene, the product has the equilibrium composition of approximately 24 percent of 1,4-, 54 percent of 1,3- and 22 percent of 1,2-isomer. Of the dialkylbenzene isomers, 1,3-dialkylbenzene is often the least desired product, with 1,2- and 1,4-dialkylbenzene being the more useful products. 1,4-Dimethylbenzene, for example, is of particular value, being useful in the manufacture of terephthalic acid which is an intermediate in the manufacture of synthetic fibers such as "Dacron". Furthermore, 1,4-methylethylbenzene, i.e., para-ethyltoluene (PET), is useful for subsequent conversion to para-methylstyrene, and for this purpose ethyltoluene products containing as much as 97% of the para isomer are required. Mixtures of dialkylbenzene isomers, either alone or in further admixture with ethylbenzene, have previously been separated by expensive superfractionation and multistage refrigeration steps. Such processes, as will be realized, involve high operation costs and have a limited yield. Alternatively, various modified zeolite catalysts have been developed to alkylate or disproportionate toluene with a greater or lesser degree of selectivity to 1,4-dialkylbenzene isomers. Hence, U.S. Pat. Nos. 3,972,832, 4,034,053, 4,128,592, and 4,137,195 disclose particular zeolite catalysts which have been treated with compounds of phosphorus and/or magnesium to increase para-selectivity of the catalysts. Para selective boron-containing zeolites are shown in U.S. Pat. No. 4,067,920 and para-selective, antimony-containing zeolites in U.S. Pat. No. 3,979,472. Similarly, U.S. Pat. Nos. 3,965,208 and 4,117,026 disclose other modified zeolites useful for shape selective reactions. Notwithstanding the existence of such modified zeolite catalysts having para-selective properties, there is a continuing need to develop additional types of catalytic materials which are highly para-selective when used for the conversion of aromatic compounds to dialkylbenzene products. Accordingly, it is an object of the present invention to provide modified zeolite catalyst compositions which promote the conversion of aromatics to produce mixtures containing an exceptionally high percentage, e.g., 97% by weight or more, for alkylation of toluene, of para-dialkylbenzene isomer. It is a further object of the present invention to provide such highly para-selective catalysts without necessarily resorting to expensive and/or time consuming catalyst selectivation techniques such as steaming and/or precoking after each instance of catalyst regeneration. It is a further object of the present invention to provide highly para-selective alkylation, transalkylation and disproportionation processes employing the modified zeolite catalysts described herein.
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/* JPC: An x86 PC Hardware Emulator for a pure Java Virtual Machine Copyright (C) 2012-2013 Ian Preston This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License version 2 as published by the Free Software Foundation. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301 USA. Details (including contact information) can be found at: jpc.sourceforge.net or the developer website sourceforge.net/projects/jpc/ End of licence header */ package org.jpc.emulator.execution.opcodes.vm; import org.jpc.emulator.execution.*; import org.jpc.emulator.execution.decoder.*; import org.jpc.emulator.processor.*; import org.jpc.emulator.processor.fpu64.*; import static org.jpc.emulator.processor.Processor.*; public class fdivrp_ST0_ST3 extends Executable { public fdivrp_ST0_ST3(int blockStart, int eip, int prefices, PeekableInputStream input) { super(blockStart, eip); int modrm = input.readU8(); } public Branch execute(Processor cpu) { double freg0 = cpu.fpu.ST(0); double freg1 = cpu.fpu.ST(3); if (((freg0 == 0.0) && (freg1 == 0.0)) || (Double.isInfinite(freg0) && Double.isInfinite(freg1))) cpu.fpu.setInvalidOperation(); if ((freg0 == 0.0) && !Double.isNaN(freg1) && !Double.isInfinite(freg1)) cpu.fpu.setZeroDivide(); cpu.fpu.setST(0, freg1/freg0); cpu.fpu.pop(); return Branch.None; } public boolean isBranch() { return false; } public String toString() { return this.getClass().getName(); } }
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30
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Q: How can I update system controls setting on container running in ECS Fargate? Based on AWS doc: https://docs.aws.amazon.com/AmazonECS/latest/userguide/task_definition_parameters.html It says systemControls is not supported for Windows containers or tasks using the Fargate launch type.. I wonder how I can configure net.core.somaxconn for the container on Fargate. Is it not supported at all? Or is there any other ways to do that? A: In the above link, this is clearly mentioned that fargate does not support systemControls Note systemControls parameter is not supported for Windows containers or tasks using the Fargate launch type. There is a difference between in EC2 launch type and fargate launch type, consider fargate launch type a kind of serverless, so you can use EC2 launch type.
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Mariko Okubo is a Japanese model and actress based in Taiwan. Early life Okubo was born in Nagasaki Prefecture, Japan, on September 7, 1984. Career Okubo debuted as a gravure idol in 2003. She later started a career in acting, moving to Taiwan in 2011. In 2013, she won the Golden Bell Awards for Best Supporting Actress in Taiwan. Filmography Film SS (2008) La Lingerie (2015) The Bold, the Corrupt, and the Beautiful (2017) Television Toritsu Mizusho! (2006, NTV), Naomi Juken Sentai Gekiranger (2007, TV Asahi) GodHand Teru (2009, TBS), Kaori Hasegawa Orthros no Inu (2009, TBS) Substitute for Love (2012, PTS) Shia Wa Se (2015, TTV) References External links Category:1984 births Category:Japanese actresses Category:Japanese expatriates in Taiwan Category:Japanese gravure idols Category:Japanese television personalities Category:Living people Category:Actors from Nagasaki Prefecture Category:Models from Nagasaki Prefecture
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55
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Efficient organic photovoltaic diodes based on doped pentacene. Recent work on solar cells based on interpenetrating polymer networks and solid-state dye-sensitized devices shows that efficient solar-energy conversion is possible using organic materials. Further, it has been demonstrated that the performance of photovoltaic devices based on small molecules can be effectively enhanced by doping the organic material with electron-accepting molecules. But as inorganic solar cells show much higher efficiencies, well above 15 per cent, the practical utility of organic-based cells will require their fabrication by lower-cost techniques, ideally on flexible substrates. Here we demonstrate efficiency enhancement by molecular doping in Schottky-type photovoltaic diodes based on pentacene--an organic semiconductor that has received much attention as a promising material for organic thin-film transistors, but relatively little attention for use in photovoltaic devices. The incorporation of the dopant improves the internal quantum efficiency by more than five orders of magnitude and yields an external energy conversion efficiency as high as 2.4 per cent for a standard solar spectrum. Thin-film devices based on doped pentacene therefore appear promising for the production of efficient 'plastic' solar cells.
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Round Dining Table for 8 Round Dining Table for 8 – Each part entrance should have some other form and uniqueness. Including the living area at home. Not simply could be the dining-room a place to enjoy with your loved ones, you’ll find it becomes methods to gather and hang out with family. One important aspect in the dining area will be the dining table. Indeed, the development of the structure and model of the dining room table itself will vary, without considering the utilization and ergonomic aspects of the dining room table itself. Well, on this occasion Kania is evaluating a specialized table design and almost always is an inspiration to your dining room. Like what? Come see round dining table for 8 below!
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Bioequivalence of two lithium formulations in healthy volunteers. The purpose of this study was to compare the maximum exposure and extent of bioavailability of two lithium carbonate (CAS 554-13-2) containing 300 mg tablet formulations (test and reference) for oral administration. This bioequivalence study was conducted in a 2-period crossover design with a washout phase of 7 days. Plasma samples were obtained by blood sampling over 72 h in each period. Twenty-four healthy volunteers of both genders participated in the trial. Samples were analyzed by a flame atomic absorption spectrometer. Resulting Li+ concentrations were used for determination of the pharmacokinetic parameters AUC(last), AUC(inf) and C(max). 90 % confidence intervals for AUC(last), AUC(inf) and C(max) were 96.81-107.44%, 98.44-109.54% and 98.60-111.33%, respectively. All 90% and 95% confidence intervals were inside the limits defined by the FDA Guidance for Industry (80%-125%) and thus stated that test and reference formulation may be accepted as bioequivalent, with regard to both, maximum exposure and extent of bioavailability.
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Dynamos FC (Bahamas) Dynamos FC is a Bahamian football club based in Nassau. The club competes in the BFA Senior League, the top tier of Bahamian football. The club was founded in 1957, and play their home matches in the 1,700-capacity, Roscow A. L. Davies Soccer Field. Squad References External links BFA Club Profile Category:Football clubs in the Bahamas Category:1957 establishments in the Bahamas
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Q: Pass an @State variable to a Class so it can make changes to it The code below is what I'm trying to attempt. I want to pass the @State myName to the class, and allow changes to it when buttons are pressed. (There a whole bunch more, this is the only part I'm stuck on). When I run this, there are no errors, but it doesn't do anything. If I change it to self.helper.fieldBeingEdited = self.$myName, it gives an error. The class Helper has more code in it and it appears it has to be a class, not a struct. Is there an easy way to do this? I should also mention that in the end, multiple textFields will use the same Helper, each sending their @State var to the Helper to be changed by the changeField(). Updated question for clarification for what I'm trying to achieve: I want the TextField to change myName and I want to pass myName to a class that will be able to modify it (by pressing a button). But I also want to be able to pass otherName to the same helper class. class Helper: ObservableObject { @Published var fieldBeingEdited: String = "" func changeField() { fieldBeingEdited = "Something else" } } struct ContentView: View { @State var myName = "John" @State var otherName = "Paul" var helper = Helper() var body: some View { VStack { TextField("Your Name", text: $myName) .onTapGesture { self.helper.fieldBeingEdited = self.myName } TextField("Other Name", text: $otherName) .onTapGesture { self.helper.fieldBeingEdited = self.otherName } Button(action: { self.helper.changeField() }) { Text("Change") } } } } A: I think this will accomplish your (perhaps questionable) goals: class Helper: ObservableObject { var fieldBeingEdited: Binding<String> = .constant("init") func changeField() { fieldBeingEdited.wrappedValue = "Something else" } } struct ContentView: View { @State var myName = "John" @State var otherName = "Paul" var helper = Helper() var body: some View { VStack { TextField("Your Name", text: $myName) .onTapGesture { self.helper.fieldBeingEdited = self.$myName } TextField("Other Name", text: $otherName) .onTapGesture { self.helper.fieldBeingEdited = self.$otherName } Button(action: { self.helper.changeField() }) { Text("Change") } } } } Bear in mind that onTapGesture isn't the only way a text field could become active, so you might be better off using the TextField's editing callbacks to set the fieldBeingEdited.
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Q: Infinite loop while trying to read from file I wanted to read bytes from file and then rewrite them. I did like so: FILE *fp; int cCurrent; long currentPos; /* check if the file is openable */ if( (fp = fopen(szFileName, "r+")) != NULL ) { /* loop for each byte in the file crypt and rewrite */ while(cCurrent != EOF) { /* save current position */ currentPos = ftell(fp); /* get the current byte */ cCurrent = fgetc(fp); /* XOR it */ cCurrent ^= 0x10; /* take the position indicator back to the last position */ fseek(fp, currentPos, SEEK_SET); /* set the current byte */ fputc(cCurrent, fp); } After executing the code on a file, the size of the file is increasing within an infinite loop. What is the problem in my code? A: You are XOR-ing cCurrent with 0x10 even if it's equal to EOF. Once you XOR, it's no longer EOF, so your loop never terminates. Make the loop infinite, and exit from the middle when you see an EOF, like this: for (;;) { /* save current position */ currentPos = ftell(fp); /* get the current byte */ if ((cCurrent = fgetc(fp)) == EOF) { break; } /* XOR it */ cCurrent ^= 0x10; /* take the position indicator back to the last position */ fseek(fp, currentPos, SEEK_SET); /* set the current byte */ fputc(cCurrent, fp); /* reset stream for next read operation */ fseek(fp, 0L, SEEK_CUR); }
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South Ward School (Cresco, Iowa) The South Ward School was a historic building located in Cresco, Iowa, United States. It served as a grade school from 1897 to 1978. Because of low enrollment it was not used from 1949 to 1953. The 2½-story brick structure was built on a raised limestone basement, and it was capped with a hipped roof. It was significant as a good example of late Victorian-style school buildings with Romanesque influences. It was listed on the National Register of Historic Places in 1982. The school building has subsequently been torn down and replaced with a modern apartment building. It was removed from the NRHP in September of the same year. References Category:School buildings completed in 1896 Category:Victorian architecture in Iowa Category:Romanesque Revival architecture in Iowa Category:School buildings on the National Register of Historic Places in Iowa Category:Defunct schools in Iowa Category:Buildings and structures in Howard County, Iowa Category:National Register of Historic Places in Howard County, Iowa
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P1 is now webe ! | gainsinfo.com by Marc Soon Joo Yee April 16, 2016 Packet One Networks (Malaysia) Sdn Bhd (P1) today rebranded to webe on the 13 April 2016. webe is the a new digital mobility services provider soon to launch its LTE network in Malaysia. webe’s business and network services are approaching market readiness, on track for a commercial launch soon this year. CC Puan reveals P1 is now webe webe’s brand philosophy is unique – ‘start here. go anywhere’. This exemplifies the diversity of ways communities can come together to make things happen, for a better Malaysia. CC Puan, CEO of webe and James Chong, Chief Calibrator, webe community with the webe team As a testament to the company’s commitment to focusing on developing deeper relationships with the community, webe launched its online community platform called ‘webe community’.webe community is a unique crowd-backing platform to enable Malaysians to connect, collaborate and co-create and make what Malaysians care about happen together. webe community platform empowers individual groups and members of the local community to band together to make things happen with people who can make it happen.
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Q: Does 'can' express definite possibility? Consider a sentence Scotland can be very warm in September. Here, does it mean that Scotland will surely be very warm in September or does it mean that Scotland may or may not be very warm in September? A: Uncertainty is a poor term to describe what can expresses. It's true that can implies a kind of "uncertainty" about any future eventuality; it takes for granted that the future is inherently unknowable and cannot be predicted. But can doesn't address certainty: it is concerned with possibility. It asserts quite confidently that a hypothetical eventuality is not impossible. In many cases can implies that the eventuality has occurred in the past: John can bench-press 400 pounds. (I've seen him do it). Scotland can be quite warm in September. (When I was there in '05 it occasionally hit 80 degrees). In other cases can expresses contingent possibility: If you study diligently you can pass this test. Can stops short of predicting that a future eventuality will occur, but it emphatically denies the validity of any assertion that the eventuality cannot occur. A: In your context applies the definition #2 a. from the American Heritage® Dictionary of the English Language: can 2 a. Used to indicate a possibility or probability: I wonder if my long lost neighbor can still be alive. Such things can and do happen. This said, it means that Scotland may or may not be very warm in September, so the potential exists but we don't know for sure what is going to happen.
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Vitamin C reverses lead-induced deficits in hippocampal synaptic plasticity in rats. Lead (Pb) is a neurotoxic metal that is widely distributed in the environment. In experimental animals, chronic exposure to this neurotoxicant resulted in impaired synaptic plasticity and cognitive function. In this study, we examined the protective effects of vitamin C (ascorbic acid) against Pb exposure-induced impairment of long-term potentiation (LTP). Forty-four adult male Wistar rats were divided into six groups and subjected to the following treatments for three months: (1) vehicle (distilled water); (2) Pb; (3) ascorbic acid; (4) Pb+ascorbic acid; (5) Pb (two months) followed by ascorbic acid; and (6) ascorbic acid (one month) followed by Pb. After treatment, the population spike (PS) amplitude and slope of excitatory postsynaptic potentials (EPSP) were measured in the dentate gyrus(DG) of rats in vivo. Following these measurements, blood samples were collected for the following biochemical assays: malondialdehyde (MDA), total antioxidant capacity (TAC), and total oxidant status (TOS). There was a significant increase in plasma MDA and TOS in the Pb-intoxicated group compared to the control group. There was a significant increase in TAC levels in the ascorbic acid group. Our results also show that Pb exposure caused a decrease in the EPSP slope and PS amplitude when compared with the control group, whereas vitamin C increased these parameters. Co-administration of Pb with vitamin C inhibited the effects of Pb. These findings suggested that Pb exposure caused impairment in LTP, that may have been mediated through oxidative damage. Vitamin C ameliorated the Pb-induced impairment of synaptic plasticity in the DG via antioxidant activity.
{ "pile_set_name": "PubMed Abstracts" }
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The Advisory Committee on Immunization Practices (ACIP) from the Centers of Disease Control and Prevention (CDC) has issued its recommended immunization schedule for adults aged ≥19 years in the US. Changes in the 2018 adult immunization schedule from the previous year’s schedule include new ACIP recommendations on the use of recombinant zoster vaccine (RZV) to prevent shingles in adults aged ≥50 years and the use of an additional dose of measles, mumps, and rubella vaccine (MMR) in a mumps outbreak setting. The update includes the following recommendations: The change in recommendation to preferential use of RZV (Shingrix) is a large and exciting one. It is large because the recommendation begins at age 50, an age where we are not currently used to recommending vaccination, so it will take a concerted effort to integrate this into practice. It is also large because it has the potential to benefit many people given the much better efficacy of RZV in preventing shingles than the previous vaccine. Vaccination in adults is an important area to emphasize, as vaccination coverage rates for adults in the US are lower than they should be. For those eligible for vaccination, current rates of vaccination are: influenza (45%); Tdap (23%); zoster (31%). —Neil Skolnik, MD
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Lithium adduct as precursor ion for sensitive and rapid quantification of 20 (S)-protopanaxadiol in rat plasma by liquid chromatography/quadrupole linear ion trap mass spectrometry and application to rat pharmacokinetic study. A novel, rapid and sensitive liquid chromatography/quadrupole linear ion trap mass spectrometry [LC-ESI-(QqLIT)MS/MS] method was developed and validated for the quantification of protopanaxadiol (PPD) in rat plasma. Oleanolic acid (OA) was used as internal standard (IS). A simple protein precipitation based on acetonitrile (ACN) was employed. Chromatographic separation was performed on a Sepax GP-C18 column (50 × 2.1 mm, 5 μM) with a mobile phase consisting of ACN-water and 1.5 μM formic acid and 25 mM lithium acetate (90 : 10, v/v) at a flow rate of 0.4 ml/min for 3.0 min. Multiple-reaction-monitoring mode was performed using lithium adduct ion as precursor ion of m/z 467.5/449.4 and 455.6/407.4 for the drug and IS, respectively. Calibration curve was recovered over a concentration range of 0.5-100 ng/ml with a correlation coefficient >0.99. The limit of detection was 0.2 ng/ml in rat plasma for PPD. The results of the intraday and interday precision and accuracy studies were well within the acceptable limits. The validated method was successfully applied to investigate the pharmacokinetic study of PPD after intravenous and gavage administration to rat.
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Q: antd dropdown : selected value displaying outside the select I my code I am using ant Design (antd). In my drop down list I am using <span> tag to dispaly my listings as two columns. <Select value={'AccountID'} style={{'width':'212px','height':'32px'}} placeholder="Select An Accounts"> <Option disabled value='0'>Select An Account</Option> {this.props.accountList.length && this.props.accountList.map((value,index)=>( <Option value={value.AccountID} key={index}> {value.Name} <span style={{float:'right'}}> {value.TypeName} </span> </Option> ))} </Select> The problem is when I select a long option like Freight and Shipping Costs , after selecting CostOfGoodsSold is displayed outside the conttrol as shown below. As an alternate solution, If I increase the with of the select tag:- there is no space showing between the two values after selection. I need space between values. How to overcome this issue? PS: any other CSS not applied. Demo: sandbox A: As per your requirement I would like to use percentage to resolve your issue, there is one property called dropdownStyle in antd which you can use to design the options of the dropdown. so, by applying dropdownStyle={{ minWidth: "50%", height: "32px" }} You should be able to get the options added. Here is what your select looks like <Select placeholder="Select An Account" dropdownStyle={{ minWidth: "50%", height: "32px" }} style={{ minWidth: "50%", height: "32px" }} > <Option value="1"> Freight and Shipping Cost <span style={{ float: "right" }}> Cost of Goods Sold</span> </Option> <Option value="2"> Sales <span style={{ float: "right" }}> Income</span> </Option> </Select> after selecting the dropdown there is no property I can find to overwrite so you need to apply css to that. for selected item. .ant-select-selection-selected-value { width: 100%; } Demo of sandbox
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You got a new macbook? Why don't I show you what to do with it? 170 shares
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Comparative study between Wits appraisal and I line. By using a sample of 104 young people of both sexes, 17 of them with a good relation of tooth apical base and little or no incisor discrepancy, the authors tried to establish a possible relationship between the Wits appraisal and the I line and to examine the several correlations among selected groups. The authors find that the values obtained through the two methods together might give a rapid view of the cephalometric condition of the patient with regard to the relationship of the apical structures and discrepancy in the lower incisor relation to the maxillomandibular complex. Based on the findings, the following conclusions might be drawn: Nearly 16% of the sample had a good apical relation and little or no incisor discrepancy The majority of the male population was represented by individuals with a good relation of apical bases and negative discrepancy (dental protrusion) The majority of the female sample was represented by patients with deficient apical relation (slight mandibular protrusion) and negative incisor discrepancy (dental protrusion). The simultaneous usage of Wits appraisal and I line evaluation can offer a simple way to get an objective and rapid vision of the maxillomandibular relation and the incisor discrepancy. But only a meticulous complete clinical and cephalometric examination can establish the critical elements that compose a diagnosis, considering the aetiopathogenesis of the anomalies of the patient and the related data, to proceed with the execution of the correct therapy to be applied in orthodontic treatment.
{ "pile_set_name": "PubMed Abstracts" }
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I. Field of the Invention The present invention relates generally to a surgical implant and, more particularly, to an embroidered implant with resorbable flanges. II. Discussion of the Prior Art Various forms of disc replacement are in use, although historically the favored treatment particularly for a failed cervical disc has been disectomy followed by fusion, using a block or plug of bone inserted into the front of the disc space and abutting into the vertebrae above and below. This bone graft may or may not be stabilized using a plate fastened across the front of the disc space. Although fusion may relieve the symptoms for which the surgery was indicated, the loss in mobility of the particular spinal segment is undesirable, particularly in the cervical spine. The fusion of the disc segment also results in hypermobility of the motion segments above and below the fusion with increased strain on the adjacent discs, which can result in their accelerated degeneration, which will in turn require surgical intervention. Fusion using bone graft will have associated donor site morbidity if the bone is autograft or associated risks of infection if the bone is allograft. Alternatively, following the disectomy the disc space may be left empty, but this may lead to hypermobility problems at the operative level, kyphosis, spontaneous fusion and a loss in foraminal height. Disc prostheses based on either articulating metal plates or metal end plates supporting a polyethylene spacer are in clinical use. Articulating devices reduce the loss in spinal mobility and the degeneration of adjacent discs. However, optimal positioning of the articulating disc prosthesis can sometimes prove challenging. The articulation also tends to be non-viscoelastic, with a fixed axis of rotation and can be under-constrained in axial rotation and distraction such that it does not truly emulate normal motion. As well as the general geometry mismatch, such prosthesis can also be adversely affected by the ingrowth of scar tissue. The present invention is directed at overcoming, or at least improving upon, the disadvantages of the prior art.
{ "pile_set_name": "USPTO Backgrounds" }
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Calif. Wine Collector Convicted of Fraud NEW YORK (AP) — A California wine collector and influential peddler of rare vintages was convicted Wednesday of fraud for manufacturing fake old wine in his kitchen. Rudy Kurniawan, whose family gained wealth operating a beer distributorship in Indonesia, was expressionless after being convicted of mail and wire fraud for selling more than $1.3 million worth of counterfeit bottles to other wealthy collectors. The verdict was rendered by a Manhattan jury that deliberated less than two hours. U.S. District Judge Richard M. Berman set sentencing for April 24. After Kurniawan, 37, was led out of the courtroom by U.S. marshals, attorney Jerome Mooney said his client was disappointed. Mooney said the trial had revealed the "don't ask, don't tell" culture in the high-end vintage wine business over what was being sold. In closing arguments a day earlier, prosecutors said Kurniawan put on a "magic show" to fool aficionados into thinking he had access to the world's rarest wines. They said he made millions of dollars from 2004 to 2012 by manufacturing fake vintage wine in his Arcadia, Calif., kitchen. But Mooney said the government had discovered the suburban Los Angeles home of a hoarder when they arrested the Indonesian-born defendant last year, mistaking the hundreds of corks and other wine-making paraphernalia stuffed in drawers and closets as evidence that the home had been converted into a fake wine factory. Prosecutors said money from the fraud funded a lavish lifestyle in suburban Los Angeles that included luxury cars, designer clothing and fine food and drinks. Mooney said all of Kurniawan's assets have been seized or have had liens placed against them, including the Arcadia home where his 67-year-old mother resides after she obtained asylum.
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21c Museum Hotel Oklahoma City Oklahoma City, OK 21c Museum Hotel Oklahoma City is a 135-room hotel, contemporary art museum with 14,000 square feet of galleries, event space, bar, restaurant, and spa. Building on the mission of engaging the public with contemporary art and supporting the revitalization of American downtowns, 21c Oklahoma City transforms the 188,000 square foot historic Ford Motor Company Manufacturing Building that was originally designed by Albert Kahn, master of modern industrial architecture in the US. We cut through the concrete floorplate to insert new glass block lightwells that bring natural light into the core of the building. Many of our new spaces, including a distinctive round ballroom, were designed as freestanding objects set within the larger volume. Similarly, the loft-like guest rooms feature self-contained floating beds and dressers and spare modern furnishings that reflect the building’s industrial heritage.
{ "pile_set_name": "Pile-CC" }
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Texted Texted is an archive of single-work publications released online. For each issue, an artist is invited to simultaneously exhibit a work and a text piece that somehow connects to each other. These texts may appear in many forms; whether academic, as intuitive writing or simply as conceptual elements embedded in the work. By encouraging the artists to reconsider the relation between artwork and text, we wish to examine new ways of artistic communication in contemporary art, through an open platform of shifting form and content.
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Q: Formula to detect duplicate data in Excel (with a difficult variable!) I need to sanitise a mailing list, and am wondering if anyone knows of a formula to find out the following: I have an excel spreadsheet with two columns A and B, the formula I need to do is: if [value in column B is duplicated] has [blank in column A] AND [data in column A] then show the value of Column B in a new Column C. Example of data: COL A | COL B 11/11/12 | **name@example.com** 03/09/11 | different@example.com | **name@example.com** 06/01/12 | anothername@example.com The formula would detect name@example.com is duplicated & it has a date in column A & further on has no value in column A, and therefore displays: name@example.com in Column C. Hope that makes sense! A: This should work (obviously changing the ranges to cover all rows): =IF(AND(COUNTIF($B$2:$B$5,B2)>1,A2=""),B2,"")
{ "pile_set_name": "StackExchange" }
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/* * Licensed to the Apache Software Foundation (ASF) under one or more * contributor license agreements. See the NOTICE file distributed with * this work for additional information regarding copyright ownership. * The ASF licenses this file to You under the Apache License, Version 2.0 * (the "License"); you may not use this file except in compliance with * the License. You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ package org.apache.dolphinscheduler.common.utils; import org.apache.dolphinscheduler.common.Constants; import org.junit.Assert; import org.junit.Test; import static org.junit.Assert.assertNotNull; public class PropertyUtilsTest { @Test public void getString() { assertNotNull(PropertyUtils.getString(Constants.FS_DEFAULTFS)); } }
{ "pile_set_name": "Github" }
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Q: What's the worst that can happen from too much sleep deprivation? Can you die? It is well known that sleep deprivation causes considerable discomfort in humans (and has even used as a form of torture), but nevertheless there have been people who went through protracted sleep deprivation, apparently with no long term consequence. I've noticed that sleep deprivation seems to trigger an intense sense of "this is bad for me" - yet given the apparent lack of ill effects (beyond the obvious) I cannot say whether this is merely anxiety over discomfort, as opposed to a genuine perception of physiological damage. What if you were to go without sleep for as long as possible, despite the discomfort? Is it possible to commit suicide in this way (and what would be the cause of death)? Would you fail because you eventually ignore whatever stimulus was preventing sleep, and sleep anyway? Would artificially counteracting the temporary debilitating physiological effects (such as loss of body temperature) allow you to survive sleep deprivation of arbitrary length? A: The short answer is: Yes. Fatal familial insomnia is a genetically passed down disease that at some random point in a carriers life will suddenly stop them from sleeping, ever, they die within 7 to 18 months I know you did not ask about the disease, but it shows (even without illegal war tests) that it will kill you eventually, even in humans. I believe in humans without the disease a complete lack of sleep may kill them within weeks, but who knows? maybe it was the drug.
{ "pile_set_name": "StackExchange" }
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Background {#Sec1} ========== Cholangiocarcinoma (CCA) is the second most common hepatic malignancy after hepatocellular carcinoma (HCC) and has a very poor prognosis with the 5-year survival rate \< 10% \[[@CR1]\]. In terms of the location of the malignancy, CCA can be mainly divided into extrahepatic cholangiocarcinoma (ECC) and intrahepatic cholangiocarcinoma (ICC). In addition, ICC can also be categorized into mucin-producing and mucin-negative. The former arises from large bile duct cells and the latter from small bile duct cells or liver progenitor cells (LPC) \[[@CR2], [@CR3]\]. CD133 is a five-transmembrane cell-surface glycoprotein and a marker of stem cells or progenitor cells \[[@CR4]\]. It has been used for the identification of cancer stem cells (CSCs) in several types of cancers including CCA \[[@CR5]--[@CR7]\]. CD133 expression is related to poor prognosis of colon cancer and HCC \[[@CR8], [@CR9]\]. Two studies showed that CD133 positive CCA had poor prognosis, while another study demonstrated the opposite result \[[@CR10]--[@CR12]\]. How CD133 impacts progression of CCA remains unknown. Mucing-producing ICC and non-mucin producing ICC exhibit variable biological and clinicopathological features as well as different outcomes. Generally, non-mucin producing ICC is similar to cancer stem cells due to its possible origin from LPC. In this study, we enrolled patients with non-mucin producing and investigated the correlation between CD133 expression and disease prognosis. Methods {#Sec2} ======= Patients and specimens {#Sec3} ---------------------- A total of 59 non-mucin producing ICC patients confirmed by pathologically HE staining who received curative surgery from January 2004 to December 2014 (33 from Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China and 26 from University Medical Center Hamburg-Eppendorf, Hamburg, Germany) were enrolled. Two patients lost during the follow-up. Hence, 57 patients, 39 men and 18 women, were eventually included in the study. The mean follow-up duration was 25.7 ± 19.1 months. The tumor stage was determined according to the 2009 UICC TNM classification system \[[@CR13]\]. The clinical study was approved by the Ethics Committee of Shanghai General Hospital, Shanghai Jiaotong University School of Medicine and the ethics committee of Medical Association of Hamburg. Informed consent was obtained from all participants. Histology {#Sec4} --------- Liver tissues were fixed in 4% formaldehyde and embedded in paraffin. 4 μm sections was used for hematoxylin--eosin, Sirius red and immunohistochemistry (IHC) staining. The inflammation grades and fibrosis stages of the peri-tumoral tissues were examined by two experienced pathologists according to the Scheuer scoring system \[[@CR14]\]. For IHC, the sections were boiled in 10 mM sodium citrate buffer (pH 6.0) for 10 min for antigen unmasking. After cooling, the sections were incubated in peroxidase blocking reagent (Dako) for 1 h and then incubated with the following primary antibodies at 4 °C for overnight: anti-CK19 (Dako, Hamburg, Germany), 1:200; anti-CD133 (R&D Biotechnology, USA), 1:200; anti-TGF-β1 (Santa Cruz Biotechnology, USA), 1:200; anti-p-Smad2 (Santa Cruz Biotechnology, USA), 1:100; and anti-S100A4 (Sigma-Aldrich Biotechnology, Germany), 1:200; anti-E-Cadherin (1:200; Abcam) and anti-Vimentin (1:200; Abcam). Next day, the sections were incubated at room temperature with the secondary antibody and developed with diaminobenzidine for 5 min. For semiquantitative analysis, IHC scores were calculated as follows: grade 0, \< 1% positive cells; grade 1, ≥ 1% and \< 25% positive cells; grade 2, ≥ 25% and \< 50% positive cells; grade 3, ≥ 50% and \< 75% positive cells; and grade 4, ≥ 75% positive cells. Since p-Smad2 is commonly expressed in tumor cells, we also evaluated the intensity of p-Smad2 staining: grades 1--4: (1) weak positive staining: yellow; (2) moderate positive staining: brown; (3) strong positive staining: deep brown; (4) very strong: black. The final immune staining score for p-Smad2 was calculated as positive area \* staining intensity. For double-fluorescence immunostaining for E-Cadherin and Vimentin, the slides were washed with PBS and incubated with anti-E-Cadherin antibody (1:100; Abcam) at 4 °C overnight. Then, the slides were washed with PBS and incubated with anti-Vimentin antibody (1:100; Abcam) at 4 °C overnight. Next, the slides were incubated with secondary antibodies, Alexa 633 IgG and Alexa 488 IgG (Molecular Probes/Invitrogen, Karlsruhe, Germany) for 30 min at room temperature. The samples were mounted using Dako-Cytomation Fluorescence Mounting Medium. The slides were imaged with a confocal microscope (Leica, Heidelberg, Germany). Statistical analysis {#Sec5} -------------------- Data were analyzed using the SPSS version 13.0 for Windows (SPSS Inc, Chicago, IL, USA), and are presented as means and standard deviations (± SD). Student's t-test was used to compare the continuous quantitative data. A two-tailed Wilcoxon signed rank test was used to compare ranked variables. The Kaplan--Meier analysis was applied to evaluate overall and disease-free survival, and different groups were compared with the log-rank test. *p* \< 0.05 was considered to be statistically significant. Results {#Sec6} ======= CD133 expression in ICC {#Sec7} ----------------------- IHC staining showed that 30 patients (52.6%) had CD133 expression on the membrane of tumor cells. Besides cancer cells, CD133 was also expressed in peri-tumoral ductular reaction (DR). Interestingly, hepatocytes in two patients also expressed CD133 (Fig. [1](#Fig1){ref-type="fig"}a). Furthermore, we analyzed the relationship between CD133 expression and liver inflammation and fibrosis. CD133^+^ ICC displayed more severe liver inflammation and fibrosis in peri-tumoral areas than CD133^−^ ICC, although the difference was not statistically significant (*p* = 0.056 and 0.06, respectively, Fig. [1](#Fig1){ref-type="fig"}b).Fig. 1CD133 expression in tumor and peri-tumoral tissues. **a** CD133 expressed in tumor cells, peri-tumoral hepatocytes and ductular cells. **b** The relationship between CD133 expression in tumor and peri-tumoral liver inflammation and fibrosis ICC patients with CD133 expression had poor prognosis {#Sec8} ----------------------------------------------------- Next, we analyzed clinical outcome of ICC patients according to CD133 expression in tumor cells. The CD133^+^ patients had significantly higher metastasis rate than CD133^−^ patients at the time of diagnosis (36.7% vs. 10.1%, *p* = 0.03). We followed up these patients for 25.7 ± 19.1 months and found that 90.9% of CD133^+^ patients had ICC recurrence, as compared to 64.3% of CD133^−^ patients(*p* = 0.02, Table [1](#Tab1){ref-type="table"}). Survival analysis showed shorter overall and disease-free survival rates in CD133^+^ patients as compared to CD133^−^ patients (Fig. [2](#Fig2){ref-type="fig"}). These results suggested that CD133 expression was related to poor prognosis in non-mucin producing ICC patients.Table 1Comparison of clinicopathological parameters between CD133^−^ and CD133^+^ ICC patientsCD133^−^ (n = 27)CD133^+^ (n = 30)*P*Age57.4 ± 8.460.5 ± 11.50.47Gender0.76 Male19 (70.3%)20 (66.7%) Female8 (29.7%)10 (33.3%)TNM stages T0.37  1--214 (51.9%)12 (40.0%)  3--413 (48.1%)18 (60.0%) N0.41  019 (70.4%)18 (60.0%)  18 (29.6%)12 (40.0%) M0.03  024 (88.9%)19 (63.3%)  13 (10.1%)*11 (36.7%)*Differentiation0.89 1--214 (51.9%)15 (50.0%) 3--413 (48.1%)15 (50.0%)Recurrence0.02 010 (35.7%)3 (10.0%) 118 (64.3%)*27 (90.9%)* Fig. 2Survival analysis showed that overall and disease-free survival (DFS) were higher in the CD133 negative group than in the CD133 positive group CD133^+^ cancer cells demonstrated EMT markers {#Sec9} ---------------------------------------------- Given that tumor metastasis is closely associated with EMT, we performed IHC staining for S100A4, a marker of EMT, in liver tissue samples. CD133^+^ patients had higher levels of S100A4 in tumor cells than CD133^−^ patients (2.10 ± 0.21 vs. 1.12 ± 0.20, *p* = 0.001). S100A4 protein was localized in the cytoplasm, nucleus, or both. More patients had nuclear expression of S100A4 in the CD133^+^ group, although without statistical significance (65% vs. 40%, *p* = 0.193 Fig. [3](#Fig3){ref-type="fig"}a, b).Fig. 3CD133^+^ tumor cells showed EMT phenotype. **a** S100A4 expression in tumor cells. **b** Expression of total S100A4 and nuclear S100A4 was higher in the tumors of CD133^+^ patients than in CD133^−^ patients. **c** A representative patient with CD133 positive expression showed loss of E-Cadherin and expression of Vimentin as well as altered cell shape. **d** IHC staining showed the trend of higher expression of Vimentin and less expression of E-Cadherin in CD133^+^ patients than CD133^−^ patients To further verify the relationship between EMT and CD133 expression, we performed fluorescence co-immunostaining for E-Cadherin, an epithelial marker, and Vimentin, a mesenchymal marker, in CD133 positive and negative patients, respectively. As compared to CD133^−^ tumor cells, CD133^+^ ICC lost epithelial marker E-Cadherin and acquired mesenchymal marker Vimentin, indicating an EMT-like alteration in these tumor cells (Fig. [3](#Fig3){ref-type="fig"}c). IHC staining showed the trend of higher expression of E- cadherin and lower expression of Vimentin in CD133^−^ ICC than in CD133^+^ patients(*p* = 0.18 and *p* = 0.06, respectively) (Fig. [3](#Fig3){ref-type="fig"}d). Given a crucial role of TGF-β1 in EMT, we investigated the expression of TGF-β1 and its downstream protein p-Smad2 by IHC. Expression of TGF-β1 in tumor cells was seen in most ICC patients (Fig. [4](#Fig4){ref-type="fig"}a). However, CD133^+^ patients displayed higher levels of TGF-β1 expression in tumor cells than CD133^−^ patients (*p* = 0.017, Fig. [4](#Fig4){ref-type="fig"}b). Consistent with high levels of TGF-β1, CD133^+^ tumor cells also expressed higher levels of p-Smad2 than CD133^−^ tumor cells (p = 0.008, Fig. [4](#Fig4){ref-type="fig"}c, d).Fig. 4The relationship between CD133 expression and TGF-β1 signaling in tumor cells. **a** TGF-β1 expression in ICC cells. **b** CD133^+^ ICC cells had strong TGF-β1 expression; **c** p-Smad2 was expressed by CCA cells. **d** CD133^+^ ICC cells had robust p-Smad2 expression. **e** TGF-β1^+^ CCA had higher scores of p-Smad2 expression in tumor cells Discussion {#Sec10} ========== Several clinical studies had investigated the relationship between CD133 expression and clinical outcome of cholangiocarcinoma (Ref.). However, the results are controversial. Shimada and colleagues showed that CD133 expression in tumor cells was an indicator of poor prognosis for ICC patients. The 5-year survival rate was lower in CD133^+^ patients than in CD133^−^ patients (8% vs. 57%) \[[@CR10]\]. Another study with 34 ICC and perihilar CC patients also demonstrated that strong expression of CD133 in tumor was related to nodal metastasis and positive surgical margin status. Furthermore, CD133^+^ cells had a higher invasive ability in vitro \[[@CR11]\]. However, Fan et al. study with 25 ICC and 29 perihilar CC patients displayed opposite result \[[@CR12]\], wherein positive expression of CD133 in tumor cells was correlated with high or moderate tumor differentiation and predicted better prognosis of the disease. Notably, these studies included different subtypes of CCA and did not focus on ICC. ICC is divided into two groups according to the presence or absence of mucin products \[[@CR2]\]. The mucin-producing ICC arises from large bile duct epithelial cells similar to perihilar or extrahepatic CC, while the non-mucin producing ICC arises from small bile ducts or LPC. A study with 87 cases of ICC demonstrated that ICC from large ducts had significantly higher incidence of perineural invasion, lymph node metastasis, vascular invasion, intrahepatic metastasis and recurrence as well as worse survival as compared to ICC from small ducts \[[@CR15]\]. Therefore, the role of CD133 in different pathological types of CCA might be different. The current study focused on the relationship between CD133 expression and non-mucin producing ICC. We found that more than 50% of non-mucin producing ICC patients expressed CD133 in tumor cells. These CD133^+^ patients had higher metastasis and recurrence rate after surgery and worse overall and disease-free survival. These results suggested that CD133 is an indicator for poor prognosis of non-mucin producing ICC. CD133 is thought to be a marker of CSC also known as tumor-initiating cells, which are responsible for metastasis, chemotherapy resistance, and tumor recurrence \[[@CR16]\]. CSC exhibit EMT phenotype that facilitate tumor metastasis and recurrence. Thus, we investigated the relationship between CD133 expression and tumor EMT. We examined the expression of an EMT marker S100A4 in ICC tissue samples. CD133^+^ patients had higher total S100A4 and nuclear S100A4 expression. Fabris et al. showed that nuclear expression of S100A4 by CCA tumor cells was a strong predictor of metastasis and poor survival after resection by increasing CCA cell motility, invasiveness, and MMP-9 secretion \[[@CR17]\]. These findings partially explain why CD133^+^ ICC patients have poor prognosis. Next, we performed immunostaining for epithelial marker E-Cadherin and mesenchymal marker Vimentin and found that CD133^+^ ICC cells underwent EMT-like alteration characterized by lower E-Cadherin and higher Vimentin expression, indicating that EMT might be a mechanism linking CD133 expression with poor prognosis. TGF-β1 is a key cytokine for inducing EMT, which contributes to tumor metastasis and recurrence \[[@CR18]\]. Therefore, we evaluated the relationship between CD133 expression and activation of TGF-β1 signaling in ICC. As expected, CD133^+^ ICC displayed both higher levels of TGF-β1 and p-Smad2 expression. These results suggested a potential link between enhanced TGF-β1--Smad2 signaling and CD133 expression in non-mucin producing ICC. Our study demonstrated that CD133 expression in tumor cells is an indicator for poor prognosis of non-mucin producing ICC. CD133 expression in tumor cells might be associated with TGF-β1-p-Smad2-EMT axis in ICC. The underlying detailed mechanisms require further investigation in the future. Conclusions {#Sec11} =========== Our current work is the first attempt to evaluate the role of CD133 expression in tumor cells for the prognosis of non-mucin producing ICC, providing additional insights on the molecular events responsible for prognosis prediction and antitumor potency. Xiaobo Cai and Jun Li contributed equally to this work Conceived and designed the study: XJW, HLW, LGL. Collected and analyzed the data: XBC, JL, XDY. Interpreted the results and wrote the paper: XBC, JBX, SD. All authors read and approved the final manuscript. Acknowledgements {#FPar1} ================ We thank Medsci for its linguistic assistance during the preparation of this manuscript. Competing interests {#FPar2} =================== The authors declare that they have no competing interests. Availability of data and materials {#FPar3} ================================== Not applicable. Consent for publication {#FPar4} ======================= Not applicable. Ethics approval and consent to participate {#FPar5} ========================================== The clinical study was approved by the Ethics Committee of Shanghai General Hospital, Shanghai Jiaotong University School of Medicine and and ethics committee of Medical Association of Hamburg respectively. Informed consent was obtained from each participator. Funding {#FPar6} ======= Not applicable. Publisher's Note {#FPar7} ================ Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
{ "pile_set_name": "PubMed Central" }
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Q: Why do legal documents often have a place next to the date? I am talking about Switzerland. So why is there often a line for the place next to the date? Is it for some historic reason, to be easier to archive or is it to prevent fraud? Does anybody know more since when this is done and why? A: The validity of the execution of a contract is governed by the law of the place where it was signed. A location next to the date establishes that place and hence often, the governing law for the validity of that signature. If the contract does not expressly state what law governs, the contract itself is governed by the law of the place where the last signature that causes the contract to come into being, since that is where the contract was formed. The role this plays in allowing someone to prove or disprove forgery is secondary, but sometimes pertinent. The practice of noting a location as well as a date remains in place for notarized documents and court documents even in modern U.S. practice which has abandoned many of the conventions of Roman civil law and no longer routinely includes a locations next to a date line in ordinary contract executions. The location is also important in notarized documents in addition to the other reasons, because the location establishes whether the notary is acting within the notary's jurisdiction which historically involves very small geographical areas, although the modern trend has to expand the geographic range of a notary's jurisdiction. This is particularly important in a place like Switzerland, where there are relatively few good clues regarding where a contract was signed in the absence of a designation (since short distances can result in a change of jurisdiction and multiple countries share any likely language in which the contract is written) and where the substantive law that applies to the contract can vary from canton to canton even within the country. This practice proximately dates to the reception of Roman civil law in the late Middle Ages following a "lawless" period from the fall of the Roman empire through the early Middle Ages. This revived a practice that existed for most of the Roman Empire and predecessor Roman Republic in the middle Iron Age. A similar practice was used, however, in diplomatic and royal correspondence in the broad Eastern Mediterranean and Fertile Crescent region during the Bronze Age. This was done at that time partially for authentication, partially to provide context for a communication (at a time when messages wouldn't necessarily be delivered in sequence), and partially to create a historical record of a diplomat or aristocrat's travels.
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Q: How to post to a database from a form How to post the contents of a form to db? I know the database works. <form method="post" action="{{ action('UserController@registration') }}"> <h1>Please Name</h1> <textarea name="name"></textarea> <button type="submit">Access</button> </form> Route::post('/registration', 'UserController@registration'); public function registration(Request $request) { DB::table(‘user2s’)->insert([‘name’=> $request->name]); return 'success'; } A: Add this token in your form {!! Form::token() !!} or this <input type="hidden" name="_token" id="csrf-token" value="{{ Session::token() }}" />
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Q: Where to get godef binary? I'm trying to install godef binary using the command: go get -v code.google.com/p/rog-go/exp/cmd/godef However it keeps giving me error: package code.google.com/p/rog-go/exp/cmd/godef: unable to detect version control system for code.google.com/ path How do I install godef binary? A: The current source for godef is at https://github.com/rogpeppe/godef. Use the following command to install godef: go get github.com/rogpeppe/godef
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Cheese is made within block-shaped containers that are also used to ship or otherwise transport the cheese for further processing. Some of the containers are made of stainless steel with permanently joined sides, and others are made with plywood sides that are temporarily held together between metal corners by banding. These containers have approximately 80 gallons (i.e., 304 liters) of capacity for making blocks of cheese weighing nearly 700 pounds (or about 315 kilograms). The sides of the containers are assembled together to constitute a so-called "cheese hoop", which is used independently of a base and cover of the containers during the cheese-making process. The cheese is pressed from both the ends of the hoop to remove whey from the coagulated part of the cheese. The compressed cheese exerts large outward pressures against the cheese hoops, and the sides and joints between the sides of the cheese hoops must be especially strong to resist these pressures. Finished cheese is extruded in large blocks from the stainless steel containers for further processing, whereas the sides of the plywood containers can be taken apart to remove the blocks of cheese. Once removed from the containers, the blocks of cheese are further processed by forcing the blocks through a matrix of wire cutters for cutting the blocks into a number of smaller chunks. Any departure of the blocks from squareness and flatness, such as bowing, produces waste that is trimmed from the exterior of the blocks and discarded. Accordingly, the cheese containers must be made to exacting tolerances and be especially rigid. In fact, the containers are generally required to hold dimensions of the finished cheese blocks to within 3/16.sup.ths of an inch (or approximately 5 millimeters). However, the stainless steel containers tend to become dented with repeated use and produce increasing amounts of scrap. The dents also make extruding the blocks of cheese from the stainless steel containers more difficult. The plywood containers are much cheaper than the stainless steel containers and resist denting; but the plywood poses sanitation problems, and the containers are difficult to assemble. The plywood is waxed for sanitary reasons and must be refurbished before the container can be used again to make cheese.
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This invention relates generally to wellbore casings, and in particular to wellbore casings that are formed using expandable tubing. Conventionally, when a wellbore is created, a number of casings are installed in the borehole to prevent collapse of the borehole wall and to prevent undesired outflow of drilling fluid into the formation or inflow of fluid from the formation into the borehole. The borehole is drilled in intervals whereby a casing which is to be installed in a lower borehole interval is lowered through a previously installed casing of an upper borehole interval. As a consequence of this procedure the casing of the lower interval is of smaller diameter than the casing of the upper interval. Thus, the casings are in a nested arrangement with casing diameters decreasing in downward direction. Cement annuli are provided between the outer surfaces of the casings and the borehole wall to seal the casings from the borehole wall. As a consequence of this nested arrangement a relatively large borehole diameter is required at the upper part of the wellbore. Such a large borehole diameter involves increased costs due to heavy casing handling equipment, large drill bits and increased volumes of drilling fluid and drill cuttings. Moreover, increased drilling rig time is involved due to required cement pumping, cement hardening, required equipment changes due to large variations in hole diameters drilled in the course of the well, and the large volume of cuttings drilled and removed. Conventionally, at the surface end of the wellbore, a wellhead is formed that typically includes a surface casing, a number of production and/or drilling spools, valving, and a Christmas tree. Typically the wellhead further includes a concentric arrangement of casings including a production casing and one or more intermediate casings. The casings are typically supported using load bearing slips positioned above the ground. The conventional design and construction of wellheads is expensive and complex. The present invention is directed to overcoming one or more of the limitations of the existing procedures for forming wellbores and wellheads.
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As the size of integrated circuits shrinks, the number of devices within an integrated circuit has risen. For example, a rule of thumb common called Moore's Law states that the number of transistors in a state of the art integrated circuit generally doubles every eighteen months. For many years this rule of thumb has generally been true. Thus, the increase in the number of cells within an integrated circuit has grown exponentially rather than linearly. Obviously, over the past several years the number of cells within a single integrated circuit has virtually exploded. This tremendous and rapid increase in the number of active devices within an integrated circuit has come about as a result of innovation and changes in the way that the devices are designed and fabricated. Thus, many different issues have been overcome in accomplishing this increase in the capacity of integrated circuits. At the same time, however, this increase in the complexity and capacity of integrated circuits has created new challenges in regard to other aspects of integrated circuit fabrication, such as inspection. Integrated circuits are typically inspected throughout the fabrication process, both to ensure that the processes used to fabricate the integrated circuits are in control, and also to ensure that the structures formed by the various processes have the proper characteristics, and are not malformed, scratched, or contaminated. For a variety of reasons, inspections of the substrates used in integrated circuit fabrication, such as semiconductor wafers and masks and reticles, have become much more complex than they previously were. For example, the structures being formed are much smaller than they previously were, as described above. This has resulted in the inspection systems becoming commensurately more complex, so as to be able to adequately inspect the smaller structures. For this and other reasons, inspection systems require more set up and tuning than in times past, in order to provide the desired benefits. Unfortunately, training on such equipment typically requires that either the vendor travels to the customer site, or the customer travels to the vendor site. Additionally, set up or other maintenance of the equipment often requires the vendor to travel to the customer site, if the customer is unable to achieve the desired results on their own. Such travel is expensive and time consuming. What is needed, therefore, is a system by which an inspection tool can be operated remotely, so that setup, inspection, and training can be accomplished remotely, without having to be physically in front of the inspection tool.
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Field of the Invention The present invention relates to an antenna array, and in particular to an antenna array utilized in detection. Description of the Related Art Antenna technology is commonly utilized in the field of biomonitoring to help provide nursing aid the elderly persons, children, patients, and animals. For example, antenna technology may be utilized to remotely monitor whether an elderly person has fallen down, moves, or experiences potentially dangerous irregularities of breathing or heart rate. However, it is important that the signal used by the biomonitoring antenna device does not interfere with the signals of other electronic devices (the waveband of the signal of the biomonitoring antenna device cannot overlap with the waveband of the signal of other electronic devices). Therefore, conventional biomonitoring antenna devices use a narrow bandwidth, which can lead to inefficiency.
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/*************************************************************************** qgsserverlogger.h ----------------- begin : May 5, 2014 copyright : (C) 2014 by Marco Hugentobler email : marco dot hugentobler at sourcepole dot ch ***************************************************************************/ /*************************************************************************** * * * This program is free software; you can redistribute it and/or modify * * it under the terms of the GNU General Public License as published by * * the Free Software Foundation; either version 2 of the License, or * * (at your option) any later version. * * * ***************************************************************************/ #ifndef QGSSERVERLOGGER_H #define QGSSERVERLOGGER_H #include "qgsmessagelog.h" #include <QFile> #include <QObject> #include <QString> #include <QTextStream> #include "qgis_server.h" /** * \ingroup server * \brief Writes message log into server logfile * \since QGIS 2.8 */ class SERVER_EXPORT QgsServerLogger : public QgsMessageLogConsole { Q_OBJECT public: /** * Gets the singleton instance */ static QgsServerLogger *instance(); /** * Gets the current log level * \returns the log level * \since QGIS 3.0 */ Qgis::MessageLevel logLevel() const { return mLogLevel; } /** * Set the current log level * \param level the log level * \since QGIS 3.0 */ void setLogLevel( Qgis::MessageLevel level ); /** * Set the current log file */ void setLogFile( const QString &filename = QString() ); /** * Activates logging to stderr. * \since QGIS 3.4 */ void setLogStderr(); public slots: /** * Log a message from the server context * * \param message the message * \param tag tag of the message * \param level log level of the message */ void logMessage( const QString &message, const QString &tag, Qgis::MessageLevel level ) override; protected: QgsServerLogger(); private: static QgsServerLogger *sInstance; QFile mLogFile; bool mLogStderr = false; QTextStream mTextStream; Qgis::MessageLevel mLogLevel = Qgis::None; }; #endif // QGSSERVERLOGGER_H
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@noanno class Bug1155_B() { // Used for anonymous functions and method arguments shared void f(Anything(Nothing) fn) {} shared void binaryStar(String s, String* seq) { } shared void unaryPlus(String+ seq) { } shared void binaryOptStar(String s="", String* seq) { } shared void mva_callsite() { Anything(String, String*) binaryStarRef = binaryStar; f(void(String s, String* seq) {}); Anything(String+) unaryPlusRef = unaryPlus; Anything(String=, String*) binaryOptStarRef = binaryOptStar; // Illegal: Anything(String+) x = binaryStar; // Legal: Anything(String, String*) y = unaryPlus; } }
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Tanida Tanida (written: 谷田) is a Japanese surname. Notable people with the surname include: , Japanese volleyball player , Japanese curler See also "Mako Tanida", an episode of the American television series The Blacklist Category:Japanese-language surnames
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Q: Gradle build: does someone tried alternative build script with alternative setting.gradle? I am using gradle 1.4, and renamed a build.gradle to buildExpr.gradle and settings.gradle to settingExpr.gradle, both files are in the project root, and I am using following command to run gradle build. 'gradle C:\myProject>gradle -i -b buildExpr.gradle -c settingsExpr.gradle project' it seems command line option '-c' is not being honored and gradle is not picking settingsExpr.gradle file, hence it is not able to display all modules defined in settings.gradle file while executing project task. I am getting following log -------------------------------------LOG---------------------------------------------------- C:\ASM\asm_workspace\asm71\AutoLab>gradle -i -c settingsExpr.gradle -b buildExpr.gradle project Starting Build Settings evaluated using empty settings script. Projects loaded. Root project using build file 'C:\ASM\asm_workspace\asm71\AutoLab\buildExpr.gradle'. Included projects: [root project 'AutoLab'] Evaluating root project 'AutoLab' using build file 'C:\ASM\asm_workspace\asm71\AutoLab\buildExpr.gradle'. All projects evaluated. Selected primary task 'projects' Tasks to be executed: [task ':projects'] :projects Root project Root project 'AutoLab' No sub-projects it is very strange behavior by gradle command line shows. but if I change buildExpr.gradle to build.gradle and settingsExpr.gradle to settings.gradle, it executes normally and shows all sub-modules in log A: -b and -c can't be used together. When using a settings file, everything else (e.g. the locations of build files) is determined from the settings file.
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Teamwork makes the dream work! Posted On3:18 pmbylynnetta Teamwork makes the dream work!!! Apprentices helped load up another truck load of food donations at Local 255’s hall today. Again, we can’t thank the members enough for their generosity in giving back.
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Judge asserts his live streaming posed a danger to the trial integrity, and reports about the arrest were scrubbed from publications Tommy Robinson, the outspoken English activist who founded the English Defence League (EDL) only to later leave when it became too extreme, was arrested Friday while filming alleged child sex grooming gang members entering court for trial. One of the arresting officers told Robinson that he was being arrested for “suspicion of breach of peace.” Tommy Robinson has been arrested in Leeds court for reporting on grooming gangs. More updates to follow pic.twitter.com/iEPDoNOKHM — Caolan Robertson (@CaolanRob) May 25, 2018 That same day, Robinson, who was on a suspended sentence from a contempt of court arrest last year, had his suspended sentence revoked and was apparently immediately jailed. Details are sketchy because the judge ordered a complete blackout on reporting of the incident, and as a result, news media—including Breitbart News—were required to remove their stories. The resulting confusion about Robinson’s arrest, freedom of speech and of the press in the UK, varying reports of Robinson’s 13-, 14-, or 18-month prison term, and concerns about his safety in prison have flooded the internet with outrage and indignation, some righteous, some not. Fox News reports: U.K. right-wing activist and journalist Tommy Robinson was arrested and reportedly jailed Friday after he filmed members of an alleged child grooming gang entering a court for trial — but the details of his purported sentence remain murky after the judge ordered the press not to report on the case. Robinson, the former head of the English Defense League and a longtime activist against Islam and Islamic migration, was arrested after he was filming men accused of being part of a gang that groomed children. Britain has been rocked by a series of child sex scandals perpetuated by gangs of predominantly Muslim men. Video shows Robinson, whose real name is Stephen Lennon, being surrounded by as many as seven police officers as he livestreamed the incident on his phone. The police informed him he was being arrested for “breach of the peace.” The judge in Tommy Robinson's case, Denise Marson, pulled a neat trick today. She threw him in jail for 13 months, and banned anyone in the UK from talking about it. A thread on how she did it. (h/t @nickmon1112)#FreeTommy #FreeTommyRobinson pic.twitter.com/an8elg3OlB — Will Chamberlain (@willchamberlain) May 25, 2018 Fox News continues: . . . . The judge in the case on Friday slapped a reporting ban on the case. The order bans reporters from reporting on a case if there is reason to believe the reporting could prejudice a trial. The order prevents reporting until the conclusion of the trial Robinson was reporting on. The gag order led to news outlets in the U.K. removing their reporting from their websites to comply with the order. Most remaining reporting in the U.K. comments on Robinson’s arrest, but not on his purported sentencing. The really interesting question – how on earth the judge could BAN REPORTING on the trial – shows yet again how insane UK law is. Judge Marson's order cites section 4(2) of the 1981 Contempt of Court act justifying the reporting ban. pic.twitter.com/0IMfQdSoku — Will Chamberlain (@willchamberlain) May 25, 2018 The news blackout left many bewildered and angry. UPDATE: Breitbart forced to take down story about Tommy Robinson's arrest. Luckily archives are forever. Here's the story if you haven't seen it yet.https://t.co/vhkNpBUy6B pic.twitter.com/WpZgnD3MkN — Nick Monroe (@nickmon1112) May 25, 2018 UPDATE 2: Mirror's article on Tommy Robinson's arrest is ALSO GONE. Media stories are being SUPPRESSED. Again here's an archive of the story THAT WAS DELETED. https://t.co/lETdZLibxn pic.twitter.com/8RczEt3Lpd — Nick Monroe (@nickmon1112) May 25, 2018 Update 4: Russia Today (RT) article on Tommy Robinson arrest is GONE. Here's an archive of what was there. https://t.co/UeCvUfZd5X pic.twitter.com/H8eTW1M4Ml — Nick Monroe (@nickmon1112) May 25, 2018 The list goes on. The deep and abiding irony is that the judge’s decision to instate a news blackout has brought far more attention to the case than had it been treated with transparency. One aspect of all of this that has created a great deal of genuine concern is Robinson’s safety in prison. Fox News continues: Sources with knowledge of Robinson’s case spoke on condition of anonymity in part because of fear they would be arrested for contempt. One told Fox that Robinson’s lawyer warned that, considering the presence of Muslim gang members in prison, a 13-month sentence was tantamount to a death sentence. “Tommy’s lawyer said he will likely die in jail given his profile and previous credible threats, and the judge basically said he doesn’t care,” the source said. “He sentenced him to 13 months in prison.” These are not idle or unfounded concerns. In 2016, a man jailed in Britain for placing bacon sandwiches in front of the door of a mosque and a flag that had “no mosques” written on it was found dead in his jail cell. The Daily Mail reported at the time: A man jailed after leaving bacon sandwiches outside a mosque has been found dead in his cell. Kevin Crehan, 35, was halfway through a one-year prison sentence he received in July after admitting the racially-motivated attack on the Jamia Mosque in Bristol earlier this year. . . . . A St George flag with the words ‘no mosques’ was also tied to the fence outside the building in Totterdown, Bristol, and shouted racial abuse at a worshipper. In her ruling at Robinson’s sentencing last year, Judge Norton noted the defense’s concern about Robinson’s safety in prison but stated that “a very large part of me thinks, so what?” The judge ultimately suspended his sentence, but this is quite a chilling remark. Concerns about Robinson’s safety have been shared on Twitter, and a “free Tommy Robinson” petition has been started. Tommy Robinson latest: UKIP Peer Malcolm Lord Pearson has written to Home Secretary Sajid Javid today saying : if Tommy is murdered or injured in prison he and others will mount a private prosecution against Mr Javid as an accessory, or for misconduct in public office. pic.twitter.com/UMkXqBVLoR — Gerard Batten MEP (@GerardBattenMEP) May 27, 2018 Free Tommy protesters flooded Downing Street, demanding Robinson’s release. Watch: [Edited for clarity, FS. 5/27/18, 8:50 p.m.: Clarifying that the judge in the 2017 case is Judge Norton, not the same judge who ruled Friday, Judge Marson]
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The discussion below is merely provided for general background information and is not intended to be used as an aid in determining the scope of the claimed subject matter. Aspects of the invention relate to a system for mooring a vessel at an offshore site. For the offloading of tankers, in particular those that carry Liquefied Natural gas (LNG), it is at times advantageous if they can be moored offshore, in a safe and expedient manner, such that offloading can be performed well away from congested harbour and populated areas. Examples of such offshore offloading systems are known, e.g. the “Accelerate” on-board regasification project in the Gulf of Mexico. Such systems have not found application in a widespread manner. The major issues in offloading such LNG tanker offshore are many. For instance, to date, there are only a few (i.e. less than 1%) LNG tankers outfitted with re-gasification equipment. Gasification requires an expensive extension to each vessel such as to be able to re-gasify the cargo on board and this equipment is only required for typically 3 days per, say, 3 weeks and hence is cost-inefficient. It is much more efficient if LNG could be offloaded without the need for onboard re-gasification. Multibuoy moorings have been in use in the offshore oil industry for decades and various vendors supply these systems, but they all suffer from significant drawbacks if bigger ships have to be moored. It takes generally many hours to fit the mooring lines between the ship and the buoys. If any of those lines was to disconnect during the offloading a dangerous situation could occur which could even lead to collision between the vessel and any the offloading equipment near the water surface. For these reasons, most, if not all, present LNG terminals are located inside protected waters, some distance away from population centers. A standard quayside/pier arrangement is then used, such as shown in FIG. 1 of U.S. Pat. No. 6,886,611, employing rubber fenders and nylon or polyester mooring ropes to secure the vessel to the quay/pier. Since the amount of LNG import is rising dramatically, a significant shortage of suitable vessel berths will occur in the next decade, a shortage which can be mitigated by mooring and offloading such vessels offshore.
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Olive Township, Butler County, Nebraska Olive Township is one of seventeen townships in Butler County, Nebraska, United States. The population was 242 at the 2000 census. A 2006 estimate placed the township's population at 236. See also County government in Nebraska References External links City-Data.com Category:Townships in Butler County, Nebraska Category:Townships in Nebraska
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A comprehensive model describing conduction through the atrioventricular node. An algorithm which models conduction over two conduction pathways through the atrioventricular (AV) node has been derived and tested. Output from the node has been previously related to input, the coupling intervals of extrastimuli introduced during programmed atrial stimulation. An exponential model of conduction in a single pathway was used with the general form: A2 H2 = K1 + K2 exp (-A1 A2/K3) with K1, K2, K3 parameters The algorithm for identification of dual pathways minimised residual sums of squares from two such functions. Potential 'bifurcation' points were selected by significant deviation of the computed single curve of best fit. The algorithm was tested using data obtained during electrophysiology study. Three trials of programmed stimulation were performed in 15 patients after pacing at 100 bpm. Computations using the model suggested single and dual functions (and therefore pathways) respectively in 19 and 25 of 44 trials. An electrophysiologist independently examining the data usually agreed (83% of trials). As the reasons for discordance were minor the model was reasonably verified.
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When an alternating electromagnetic field, such as a high-frequency microwave, interacts with a fluid, a host of dynamic polarization processes take place within the fluid. These processes depend, in part, on the complexity of the fluid and on the physical properties of the components (e.g., the complex permittivity) that make up the fluid. Dielectric relaxation due to the electric dipole re-orientation of the fluid atoms and/or molecules, in addition to ion conductivity effects, manifest themselves in the frequency dependence of microwaves that are transmitted or reflected from the sample. The measured dielectric response is enhanced when the fluid under test passes through, or is housed within, a resonant cavity tuned to the desired measurement frequency, a process known as cavity-enhanced dielectric relaxation spectroscopy. Cavity-enhanced dielectric relaxation spectroscopy at high frequencies typically employs a metal-walled cylindrical resonator as the microwave cavity. The geometry of the resonator is chosen according to the desired operating frequency. Accordingly, the inner diameter of the cavity and, thus, the space available for a fluid sample under test is constrained by the chosen operating frequency. In a conventional metal resonator operating at 18 GHz, the peak of the resonant dielectric relaxation response of water, the presence of an opening for the fluid flow line or channel and the ohmic losses at the cavity metal walls limit the quality factor (Q-factor) of the cavity resonant mode to the order of 1,000. Dielectric interrogation of fluids at lower frequencies up to a few GHz typically does not employ resonant cavities but rather involve measurements across capacitor arms or measurements with electrodes invading the fluid volume. Optical measurements are also deployed but, like low frequency microwaves, do not involve the use of cavity resonators. Optical measurements probe the much faster electronic transitions or molecular vibrational transitions of the sample.
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The GeForce GTX 10 Series has been superseded by the revolutionary NVIDIA Turing™ architecture in the GTX 16 Series and RTX™ 20 Series. Upgrade today to experience groundbreaking features and performance for gamers and creators.
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GM1 expression in H-ras-transformed NIH3T3 results in the suppression of cell proliferation inducing the partial transfer of activated H-ras from non-raft to raft fraction. c-H-ras is located in lipid/rafts and undergoes cholesterol dependent regulation. To analyze the regulatory effects of ganglioside GM1 on the proliferation of fibroblasts transformed with mutated ras gene, GM1 synthase cDNA was transfected into NIH3T3/H-ras cells containing mutation. In the transient expression system with EGFP-fused GM1 synthase, the ratio of BrdU-positive cells among EGFP-positive cells was compared between GM1(+) transfectant cells and control cells, indicating that the transient GM1 expression suppresses cell proliferation. Then, established transfectant cells C21 and C34 expressed definite levels of GM1, and analyzed for the cell growth with the control cells D2 and D4 expressing no GM1. GM1(+) cells showed reduced proliferation compared with controls. Phosphorylation levels of ERK1/2 after FCS treatment were examined, showing that those on the GM1(+) transfectant cells increased slowly, while those in the controls rapidly reached the plateau. Fractionation of Triton X-100 extracts with sucrose density gradient ultra-centrifugation revealed that activated H-ras proteins from controls as well as NIH3T3/H-ras were completely localized in non-GEM/raft fraction. On the other hand, some portions of activated H-ras were transferred to GEM/raft fraction, i.e., 32% in C21, and 8% in C34. Since the Ras effector Raf-1 was localized in non-GEM/raft, the growth suppression might be caused, at least partly, by the movement of activated H-ras to GEM/raft fraction.
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"One should either write ruthlessly what one believes to be the truth, or else shut up." — Arthur Koestler Founded in 1823, the Union has hosted world leaders in virtually every field. These have included Presidents Nixon, Carter and Reagan, Michael Jackson, Clint Eastwood, Diego Maradona, the Dalai Lama, Benazir Bhutto and Mother Teresa. More recently we have been honoured by visits from speakers as varied as Shakira, Tony Benn, Martin Sheen, David Cameron, Sir Ian McKellen, General Petraeus, and Johnny Depp. Genius on display: One is stunned to think that, in stark contrast, some people find a certain teleprompted lightweight is a great thinker and speaker. Comments whig Ah yes. The famed Oxford Union that defeated a motion to defend their country in 1938 during their undergraduate debates. It appears that the Bertie Woosters of the Oxford Union invited an even bigger twit to speak. joethefatman Dude is correct. Good points even if he did bring up a certain former congress critter. http://theothermccain.com smitty Now, if you’re going to troll, do it right, a la whig. http://boogieforward.us/ K-Bob Yes, because obviously there’s a huge connection between a choice made by students in 1938 to roll over for the German Chancellor, and a man of today, defending the very thing Herr Hitler had hoped to destroy. Golf claps all around, old chap. Well done. What next? The connection between Rwandan Death Camps and Seattle’s legal marijuana shops? http://boogieforward.us/ K-Bob That was something I wish Romney had watched about a hundred times before steamrolling his way to a win in the primaries. Defending capitalism from the left is really that simple. Of course, I’m sure Joe Scarberry’s moment at #NRISummit had to be so, so, very much way more better. Hannan was respectfully received at Oxford, so that is something, although the young faces in the crowd were hardly understanding, by their expressions. But if you watch the EU “Parliament” when any of the critics speak, they point out failure after failure and all the broken promises, while the Euro-weenies sit silently shaking their heads and tut-tutting with their eyes. That’s disheartening – they aren’t embarrassed in the least, they think it utter rubbish to be criticized at all.
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Ever have a day when you’re not quite depressed, but you sure don’t feel up to par? While almost everyone will experience a little bit of the blues at some point in their lives, it isn’t always easy to know the best way to lift a mood that’s more or less in the dumps. When you are in recovery, it can be doubly important to learn effective methods you can use to brighten your day.One of the simplest is exercise. That’s right, exercise. If visions of sweaty bodies and working out to near exhaustion come to mind, take heart. It isn’t all that difficult to get involved in some sort of physical exercise that you can do regularly–and not worry that you need special training or you’ll be developing a bodybuilder’s physique.In fact, getting started on exercise is as simple as making the decision to do so and then acting upon that intention.First, however, here are some insights into how exercise can lift your mood in recovery.The Exercise Triple-Bundle Did you know that besides helping to stave off sadness, exercise can also reduce overall fatigue and help fight anxiety? Think of it as the exercise triple bundle–and it doesn’t cost you a penny.What is it about working out or getting out and taking a hike that results in these benefits? When you move your body, what’s really going on in there?Physically speaking, when you exercise, your brain starts producing endorphins. These are chemicals naturally found in the brain that help elevate mood, improve concentration and brain functioning, and result in an overall sense of well-being. Translation: you start to feel good.But there’s another process going on when you exercise and that is the reduction in the levels of cortisol. During stressful times, the human body exhibits a fight-or-flight syndrome. That’s due to cortisol, a steroid hormone produced under stress. You can balance out cortisol levels in the human body through exercise.And reduction in cortisol levels can help stabilize your mood and prevent an anxiety attack.What is Effective Exercising? While any exercise is better than no exercise, there is a way to ensure that you’re getting maximum benefits from your routine. Experts say that even moderate aerobic exercise, done three to four times a week, will result in a pronounced improvement in a relatively quick time frame.That’s good news for those who may be leery about having to take up a strenuous sport, engage in recreational pursuits that may require extensive conditioning, or who just want to start off easy.What you may find surprising is that different forms of exercise target different issues of depression or the blues. For example, you can recharge mentally and reduce stress with a long, peaceful walk. Whether it is in your neighborhood, up and down the sidewalks for a few-block radius of your home or at a nature preserve or a hiking trail, the location isn’t as important as the actual walk.If you are looking to maintain muscle tone and enhance your appearance at the same time you experience a greater sense of well-being, free weights might be the answer.For an immediate mood enhancement, try short, intense workouts: about 30 minutes of exercise to the point where you’re breathing hard. What this does is release pain-inhibiting endorphins that quickly go to work to lift your mood.Alternating aerobic exercise with free weights is a good workout regime for maximum overall benefit.Keep in mind that you need to start slow and work your way up to an ideal exercise routine level in order to avoid burnout. In addition, whatever you decide to do, be consistent. You don’t want to begin a routine only to put it on the back burner for weeks. After some period of time goes by, you’ll be less likely to want to return to your exercise schedule and it may be harder to get back into it due to a mental block that you’ve put in place.How to Get Started Exercising Without Killing Yourself If you want to begin a regular exercise routine, here are some tips to keep in mind so that you’re engaging in healthy exercise but not overdoing it. Be sure you’re OK to exercise. It goes without saying, but we’ll say it anyway. You need to be sure you’re fit enough to begin an exercise program. If you have any doubts about even mild forms of exercise, check with your doctor before you embark on that long, peaceful walk near your home or at the lake. Bring a friend. For some individuals, there is nothing so boring as exercising alone. That’s probably why gym memberships are so popular. But you don’t need to join an expensive gym to reap the benefits of exercising with others. When you’re going for a walk or a run or some other form of exercise where more than one can participate, bring a friend with you. Having someone to talk with while you exercise can even make exercising seem like fun. Get ready. Maybe you want or need a reminder that it’s time to exercise. This can be as simple as setting out the clothes you plan to wear the next day when you go on your walk or head out to the garden to engage in some power-weeding. You can also use post-it notes, or put alerts on your calendar or email program. As long as you get the message–when you get the message–you’ll be fine. The point is to remember to do some form of exercise daily. If a reminder will help, by all means, use it. Vary the routine. The way around certain boredom is to mix up your routine. Every other day, try walking a different route. Or, alternate free weights and aerobic exercise. Other ways to vary the routine include using different exercise machines at the gym, listening to different music, even wearing different colors or types of exercise clothing. Track schedule and progress. If you are diligent about recording your schedule and tracking your progress, great. If not, why not ask a friend or fellow workout/exercise buddy to check in with you weekly to see how much progress you’ve made toward your goals, how well you’re adhering to your exercise schedule, and to serve as a kind of mentoring pal to keep you motivated. If that friend is similarly engaged in an exercise routine or program, so much the better. You can coach and support one another. Give yourself credit – and don’t beat yourself up for missing a day. Let’s face it. There are going to be days when you just don’t feel up to your normal exercise routine. You might be under the weather, having come down with a bug that’s sweeping the office or school or that your kids brought home. Maybe you worked late at the office to finish an important project or stayed up with a sick child. At times like this, instead of feeling bad that you’re missing your workout, be encouraged by the times that you’ve met your goals in the last month and celebrate those victories. Set reasonably attainable goals. The idea here is to set goals that you can realistically expect to achieve, at least in the beginning. There’s no sense deciding that you’re going to run a marathon in one week’s time when you’ve never even walked a mile. That might be exaggerating a little, but the point is clear. You have to walk before you can run–in this case, literally. Reward yourself for goals achieved. Those reasonable goals that you can realistically achieve? You need to give yourself some accolade or reward each time you accomplish the goal that you’ve set for yourself. What the reward is should be special to you. For example, if you are diligent and consistent in your exercise routine for one week, without missing a day, a reward you consider special might be a massage or an evening out with a friend. Focus on short-term improvements. Looking for the long-term gains might result in a feeling of frustration. It’s tough to see the long view when you’re caught up in the moment – and feeling like you’ve already given it about as much as you’ve got. Instead of concentrating on how much better you look physically or how much more strength and stamina you have or how much weight you’ve lost or gained according to your goals, focus on the improvements you can see right away. These include more energy, a better mood and less stress. Other Ways Exercise Lifts Your Mood Besides working out stress and tension, there are other ways that exercise can lift your mood in recovery.First of all, when your mind is clear, it is easier to figure out solutions. Think about it. When you’re swamped with deadlines and trying to find extra hours in the day to devote to all the things you need to do–both for your recovery as well as for work, school and family–clearing your mind and allowing for a blank slate seems almost impossible. After all, aren’t your thoughts constantly churning, calculating what you have to do and how and when and most of all, can you get it all done in a single day?Exercising helps you sweep away those ceaseless and aggravating reminders that you’re not getting enough done. Here’s how to do it: Focus on your exercise. Count your breaths or your steps or repetitions. Visualize your way up the trail or around the lakeside path. Allow your mind to be swept clean of extraneous demands. You will find that once you’ve allowed room inside your head, simple and elegant solutions may manifest in the now-open space. Next, exercise gets you out of the house and the isolation trap that so many people in recovery–especially newcomers to sobriety–find themselves falling into. Aside from the benefits of being with others when you exercise, you’ll be getting out of the house and taking active steps to remove yourself from isolation. Maybe you are afraid to come into contact with others, fearful that you will make the wrong decisions or that you aren’t yet ready to communicate properly.Here is a little secret: Exercise is the great equalizer. You don’t have to say much to get benefit from it. If you’re shy and still vulnerable, you can be in a gym where others are exercising and keep to yourself. You’re still out and among people who are engaged in physical exercise. You’re getting a sense of community, even if you’re not yet ready to dive in and strike up a conversation. You’re also working on getting your body moving again, on doing something positive for yourself. You are taking action that will benefit your recovery.Establishing a regular exercise regimen means that there’s always something to look forward to. There’s no worry or wonder about what you’re going to do tomorrow morning. You already have your schedule figured out. It’s just a matter of doing it. You show up, literally, and you’re ready to go.Where this really makes an impact is on days when you’ve had a setback or disappointment and are feeling a little more down than usual. By getting back into your exercise routine, you can help lift yourself out of the doldrums in no time flat. You will wind up with a new perspective on whatever it was that bothered you to begin with and likely have more motivation and enthusiasm to tackle other items on your recovery to-do list.Ready, Set, Grow Just start somewhere. Go slow and take your time getting acquainted with the kind of exercise program or schedule that works best for you. Look at this as a fun project with incredible benefits.Bottom line: when you are ready–as in, you’ve made the decision to try exercise to help lift your mood–make a plan, spring into action, and watch yourself grow. In no time at all, you are likely to find that not only has your mood improved, but you have more energy, enthusiasm and joy in life. Even the everyday stresses and tensions won’t seem as high a hurdle, because now you have an effective tool to deal with them.Since there’s no time like the present, isn’t it time to consider incorporating some form of exercise into your daily routine?
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Q: Azure websites load takes very long time Hello I have recently deployed one of my application on azure portal and it is running fine as well but the issue it takes 15 SECONDS TO LOAD for the first time when site load. After site load successfully once than it runs fine but as I open after some interval time of 10 min or 20 min again it takes 15 SECONDS TO LOAD. I have read all the documents and applied the same below. Performance tips Traffic Manager Routine Azure Advisor Application Insights Azure Site Performance SOF Question Azure Resource Health Scheduler I have set Scheduler to call my application on 10 minutes of interval time but it is having the same issue as it was. The one issue I found is that, it is taking time to locate the server and than give the response so is there any routing mechanism I can provide in azure to locate the server faster? or anything else. A: Did you turn On the Always On knob in Application Settings? — https://docs.microsoft.com/en-us/azure/app-service/web-sites-configure#general-settings Always On — By default, web apps are unloaded if they are idle for some period of time. This lets the system conserve resources. In Basic or Standard mode, you can enable Always On to keep the app loaded all the time. If your app runs continuous WebJobs or runs WebJobs triggered using a CRON expression, you should enable Always On, or the web jobs may not run reliably.
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Q: Unix programming. Not sure how to use the passwd struct I've done some research and I'm still struggling with the passwd structure. http://www.opengroup.org/onlinepubs/000095399/basedefs/pwd.h.html I need to obtain the user ID however I dont think I'm using understanding it at all. int getpwuid_r(uid_t, struct passwd *, char *, size_t, struct passwd **); This method call returns a point to a structure that will contain all the data I need. I'm fairly confused on the parameters. struct passwd. Do I need to declare this first? struct passwd passwd? I'm just totally lost on how to use this. Lastly, once I fill my pointer. What calls will I use to get the data? Thanks for any help. A: In the getpwuid_r signature: int getpwuid_r(uid_t uid, struct passwd *pwbuf, char *buf, size_t buflen, struct passwd **pwbufp); uid is an input parameter - it is the UID of the user that you want to look up. The rest are essentially output parameters: the structure pointed to by pwbuf will be filled with the password information, and the pointer pointed to by pwbufp will be set to the value of pwbuf if the call was successful (and NULL if it was not). The buf and buflen pair of parameters specify a user-supplied buffer that will be used to store the strings pointed to by members of the struct passwd structure that is returned. You would use it like so (this looks up the user with UID 101): struct passwd pwent; struct passwd *pwentp; char buf[1024]; if (getpwuid_r(101, &pwent, buf, sizeof buf, &pwentp)) { perror("getpwuid_r"); } else { printf("Username: %s\n", pwent.pw_name); printf("Real Name: %s\n", pwent.pw_gecos); printf("Home Directory: %s\n", pwent.pw_dir); } If instread you want to look up a user by name to find their ID, use getpwnam_r and examine the pw_uid field of the returned struct.
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Books Will Young used to masturbate to gay porn in train toilets as a teenager while overcome with shame
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Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13.8). Average mean blood pressure while on aggressive therapy with conventional medication was 144 +/- 14 mm Hg; on minoxidil and propranolol it was 108 "/- 10 mm Hg (P less thator to optimum blood pressure control and required large doses of furosemide to control. Propranolol blunted the reflex tachycardia associated with arteriolar dilator therapy but all patients continued with a clinically hyperdynamic circulation. Seven of seven had elevated ejection fractions on echocardiogram, and two of three had elevated cardiac indices. Three of three who had heart catheterization had pulmonary hypertension which was aggravated by exercise. An additional three patients on hydralazine, propranolol, and furosemide also had pulmonary hypertension suggesting this is not unique to minoxidil. Two of thirteen developed pericardial effusions. Renal function improved in three and worsened in three.
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About “All Day” Originally mentioned in an interview with GQ on June 21st, 2014, “All Day” took all day to release, debuting 8 months later at the 2015 Brit Awards alongside grime artists Skepta, Novelist, Stormzy, Jammer, Krept & Konan, and “30 goons.” The track features little-known Minnesota artist Allan Kingdom, the ever present Theophilus London, and Sir Paul McCartney for his third collaboration with Ye. The melody of the song was inspired by a tune whistled by McCartney in a Parkinson Interview in 1999. This tune can be heard at the end of the song. “All Day” was the centerpiece of 2014’s So Help Me God before that album was scrapped. It may have inspired the album’s second title, SWISH, but had been removed from the album by the time the first SWISH (finally called The Life Of Pablo) tracklist was released in January 2016. The credits for the song were revealed on iTunes and contain a mammoth 19 names:
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Update on thiol status and supplements in physical exercise. Strenuous physical exercise represents a condition that is often associated with increased production of reactive oxygen species in various tissues. One of the most reliable indices of exercise-induced oxidant production is tissue glutathione oxidation. In humans, exercise-induced blood glutathione oxidation is rapid and subject to control by antioxidant supplementation. The objective of this brief review is to provide an update of our current understanding of cellular thiols and thiol antioxidants. Cellular thiols are critically important in maintaining the cellular antioxidant defense network. In addition, thiols play a key role in regulating redox-sensitive signal transduction process. Lipoic acid is a highly promising thiol antioxidant supplement. Recent studies have clarified that while higher levels of oxidants may indeed inflict oxidative damage, oxidants are not necessarily deleterious. Under certain conditions oxidants may function as cellular messengers that regulate a multitude of signal transduction pathways. In light of this, the significance of oxidants in various aspects of biology needs to be revisited.
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Q: Interface Builder Accessibility Label Spanning Multiple Elements Does anyone know of a way to have a single value for an accessibility label span across multiple elements? I have two labels that form a single title line and the screen reader reads them separately. I have tried selecting both and applying the setting and it doesn't work. EDIT: Here is a view of my storyboard... However, when the screen readers reaches this point, it reads the first label (not using the accessibility value) and then the second label. A: We can group elements using UIAccessibilityElement class and provide a combined frame of the elements you want to group using accessibilityFrameInContainerSpace property. //From Apple Docs let profileElement = UIAccessibilityElement(accessibilityContainer: headerView) profileElement.accessibilityLabel = profileNameLabel.text profileElement.accessibilityValue = openPostsLabel.text profileElement.accessibilityTraits |= UIAccessibilityTraitButton // Tells VoiceOver to treat our new view like a button let combinedLabelFrame = profileNameLabel.frame.union(openPostsLabel.frame) let profileElementFrame = combinedLabelFrame.union(profileImageView.frame) //providing union of frames. // This tells VoiceOver where the element is on screen so a user can find it as they touch around for elements profileElement.accessibilityFrameInContainerSpace = profileElementFrame Check apple docs Whats new in accessibility. Link for sample app explaining how to do it.
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Eddie, Old Bob, Dick and Gary Eddie, Old Bob, Dick and Gary is the debut album by UK punk rock band Tenpole Tudor. The title is a play on the phrase "any old Tom, Dick or Harry". A moderately successful seller, peaking at No. 44 in the UK Albums Chart, the album launched three singles: "Three Bells in a Row", "Wünderbar" and "Swords of a Thousand Men". "Wünderbar" rose to No. 16 on the UK Singles Chart. "Swords of a Thousand Men" was the most successful of Tenpole Tudor's singles, reaching No. 6 and remaining on the charts for 12 weeks. The album was reissued on CD in 2007 on the See label. Critical reception Ira Robbins of Trouser Press lauded the band's single releases as "classy trash", noting that on the better tracks of the album, Tenpole Tudor's "good humor and rock energy are undeniably infectious". AllMusic, expressing surprise at the album's number of "flat-out excellent songs", judges the album as "a thrillingly primitive rock & roll record". Track listing Unless otherwise indicated, all songs by Eddie Tudorpole. 1981 LP (SEEZ 31) "Swords of a Thousand Men" "Go Wilder" (Dick Crippen, Bob Kingston, Tudorpole) "I Wish" "Header Now" (Gary Long, Tudorpole) "There are Boys" "Wünderbar" "3 Bells in a Row" (Crippen, Kingston, Long, Tudorpole) "Tell Me More" "Judy Annual" (Long, Tudorpole) "I Can't Sleep" (Kingston, Long, Tudorpole) "Anticipation" "What Else Can I Do" "Confessions" 1991 CD reissue (REP 4220-WY) "Swords of a Thousand Men" - 2:57 "Go Wilder" - 2:37 "I Wish" - 3:27 "Header Now" - 2:44 "There are Boys" - 4:35 "Wunderbar" - 3:00 "3 Bells in a Row" - 3:02 "Tell Me More" - 3:09 "Judy Annual" - 2:32 "I Can't Sleep" - 2:08 "What Else Can I Do" - 2:21 "Confessions" - 3:50 "Fashion" (Live at the Marquee) - 2:44 "Rock and Roll Music" (Live at the Marquee) - 2:10 "Love and Food" - 2:47 "Wunderbar" (Hit Single Version) - 3:00 "Tenpole 45" - 4:09 "There Are Boys" (Son of Stiff Version) - 4:35 1993 CD reissue (STIFFCD 06) "Swords of a Thousand Men" - 2:57 "Go Wilder" - 2:37 "I Wish" - 3:27 "Header Now" - 2:44 "There are Boys" - 4:35 "Wunderbar" - 3:00 "3 Bells in a Row" - 3:02 "Tell Me More" - 3:09 "Judy Annual" - 2:32 "I Can't Sleep" - 2:08 "What Else Can I Do" - 2:21 "Confessions" - 3:50 "Love and Food" - 2:47 "There Are Boys" (Son Of Stiff Version) - 4:35 "Wunderbar" (Hit Single Version) - 3:00 "There are Boys" is mistitled as "There are the Boys" on both the 1991 and 1993 CD reissues. 2007 CD reissue (CDSEEZ 31) "Swords of a Thousand Men" - 2:57 "Go Wilder" - 2:37 "I Wish" - 3:27 "Header Now" - 2:44 "There are Boys" - 4:35 "Wunderbar" - 3:00 "3 Bells in a Row" - 3:02 "Tell Me More" - 3:09 "Judy Annual" - 2:32 "I Can't Sleep" - 2:08 "Anticipation" - 2:01 "What Else Can I Do" - 2:21 "Confessions" - 3:50 "3 Bells in a Row" (Original Single Version) - 3:02 "Fashion" (Live at the Marquee) - 2:44 "Rock and Roll Music" (Live at the Marquee) - 2:10 "Love and Food" - 2:47 "Wunderbar" (Hit Single Version) - 3:00 "Tenpole 45" - 4:09 "There Are Boys" (Son Of Stiff Version) - 4:35 "Wunderbar" (Live from London University - Son Of Stiff Tour) - 2:49 "Real Fun" (Live from London University - Son Of Stiff Tour) - 2:43 "Go Wilder" (Live from London University - Son Of Stiff Tour) - 2:18 Personnel Tenpole Tudor Dick Crippen – bass, vocals, producer Bob Kingston – guitar, vocals Gary Long – percussion, drums, vocals Eddie Tudorpole – guitar, saxophone, vocals Munch Universe – guitar, vocals Technical Bob Andrews – producer Alan Winstanley – producer References Category:1981 debut albums Category:Tenpole Tudor albums Category:Stiff Records albums Category:Albums produced by Alan Winstanley
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Champigny-sur-Marne is a banlieue about eight miles south-east of the centre of Paris. Algeria’s coach, Djamel Belmadi, was born there; Senegal’s coach, Aliou Cissé, moved there from Ziguinchor at the age of nine (Cissé is one day older). Since then they have performed an awkward dance, always threatening to meet and very rarely doing so. They played against each other at youth level. They came head-to-head in a league game between Marseille and Paris Saint-Germain in February 2001, and then with their national teams two months later. Belmadi was at Southampton when Cissé was at Portsmouth but they never played against each other in England. And on Friday, on the greatest stage either has yet trod, their sides will meet in the final of the Africa Cup of Nations. Aliou Cissé’s battling Senegal side stand one win away from greatness Read more Such are the complexities of nationality, though, that this is also the first time since 1998, and only the sixth time in the tournament’s history, that both finalists will be managed by a “home” coach. Both Cissé and Belmadi are in charge of squads made up of players whose experiences have been similar, who understand the life of a footballer who plays his club football in one country but plays international football often on another continent. There is no guarantee there will be another Cissé or Belmadi ready to replace them, but equally their achievements, and the fact that, with varying degrees of success, Ivory Coast, Ghana and DR Congo have eschewed the familiar list of itinerant Europeans (in total 14 of the 24 nations in Egypt were managed by foreigners) feels as if it is a step in the right direction. Algeria beat Senegal 1-0 in the group stage and, as the Nigeria manager, Gernot Rohr, acknowledged, they have been the most impressive side in the tournament. Given they finished bottom of their qualifying group for the 2018 World Cup, well-beaten by a Nigeria side they beat in the semi-final, that represents a remarkable improvement. For the Nottingham Forest midfielder Adlène Guédioura, the development is primarily attributable to Belmadi, who took over last August. “He really knows the players and really knows what he wants, and the good thing as well is he knows how to pass that on to the players,” he said. “It’s important because if you don’t have a good cook you won’t have a good meal.” Rohr has spoken enthusiastically of the tactical progress made by les Fennecs. Facebook Twitter Pinterest Youcef Belaili strikes to score the decisive goal in Algeria’s win against Senegal in the group stage of the Africa Cup of Nations. Photograph: NurPhoto/NurPhoto via Getty Images Algeria in recent years had developed a reputation for attractive football undermined by indiscipline, a lack of steel, and, at times, the absence of a tactical plan. “We used to have good individuals but now we feel very strong as a team,” Guédioura said. His inclusion in the side after almost two years in the wilderness is one of Belmadi’s triumphs as he has revelled in a conservative role protecting the back four. “He was really unfairly criticised – irrationally,” Belmadi said. “I insisted he’s at the press conference today, because I wanted to credit him in front of everyone. We spoke like men before the Cup of Nations. I would even say he’s undroppable now.” In their way stand a Senegal side who are undeniably talented, but talented in one particular area: pace out wide. That was a problem for them in the quarter-final two years ago, when Cameroon sat deep, denied them space, frustrated them and eventually won on penalties, and it is likely to be a problem on Friday given how efficiently Algeria closed down the space available to Nigeria’s wingers in the semi-final. Sadio Mané will operate on one flank but through the tournament Cissé has not settled on who plays on the other wing: it could be Keita Baldé, it could be Ismaïla Sarr, it could be Krépin Diatta. Or he may do what he did at times in qualifying, seek to sidestep whatever plans Belmadi has put in place for his wide men and abandon the 4-3-3 for a more direct 4-4-2. A bigger issue than who plays wide, though, is what Cissé does at the heart of his defence. Already without Salif Sané who was injured in Senegal’s first game, he must now also find cover for the Napoli centre-back Kalidou Koulibaly who is suspended after collecting an extremely harsh yellow card in the semi-final, after he failed to get his arm out of the way of a shot in conceding the penalty Tunisia missed. The centre-forward Baghdad Bounedjah, another surprise Belmadi selection who has thrived at this tournament, has just the sort of streetwise awkwardness to take advantage of a makeshift back four. Belmadi and Cissé feel like part of a new generation of coaches, African with significant European experience, who represent the future. Both have had a significant impact on their sides, sufficient that this feels like a battle between them more than it does between, say, Sadio Mané and Riyad Mahrez, or Guédioura and Idrissa Gueye. History looms for both sides – Senegal have never won the Cup of Nations; Algeria have not won it for 29 years; Champigny will win either way.
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It’s not possible to get legal recognition for your same-sex relationship in Syria.
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If there's one lame thing about Legos, it's the lack of firearms. Luckily, BrickArms is here to fill the void. The online store creates and sells Lego weapons ($1) and custom minifigs ($10-$15). You can get everything from an UZI to an RPG Rocket Grenade, and anyone from Bond to an Arab terrorist. All of the BrickArms toys are designed used professional CAD tools and are made with Lego-approved ABS plastic. [via]
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Mike Pringle (gridiron football) Michael A. Pringle (born October 1, 1967) is an American former professional gridiron football player. A running back, he had a successful career in the Canadian Football League (CFL), during which he set or tied almost every significant league records for the position. He played college football for the California State University, Fullerton Titans and was twice signed by National Football League (NFL) teams, though he never played a game in the NFL. Along with George Reed and Johnny Bright, Pringle is one of the players most often mentioned as being the greatest running back in CFL history. In November 2006, Pringle was voted one of the CFL's Top 50 players (#4) of the league's modern era by Canadian sports network TSN. In April 2008, Pringle was inducted into the Canadian Football Hall of Fame in his first year of eligibility. Early life Pringle was born in Los Angeles, California. He attended John F. Kennedy High School in Granada Hills, California and was a student and a letterman in football. College and NFL Pringle began his college career at Washington State University. Pringle transferred to California State University, Fullerton for his junior year, where he played on the Cal State Fullerton Titans football team.. At Cal State Fullerton, Pringle shared the NCAA single-game rushing record at one time with 357 yards against New Mexico State on November 4, 1989. He also led the nation that year in all-purpose yardage with a school-record 2,690 yards. Pringle played well enough to be selected 139th overall by the Atlanta Falcons in the 1990 NFL draft. However, he would never play a down in the National Football League, spending most of the 1990 NFL season on the practice roster (although he dressed for the final three games). The final cut from Atlanta's 1991 training camp, Pringle, like fellow Cal State Fullerton alumni Damon Allen and Allen Pitts, went on to the Canadian Football League, where he became one of the best players in league history at his position. Early Canadian Football League career Pringle entered the CFL in time for the 1992 CFL season, with the Edmonton Eskimos. In three games, Pringle received 22 carries for 129 yards, posting a respectable rushing average in limited action. However, like fellow import running back Robert Hardy, the Eskimos were not high on Pringle and released him. They opted to stick with their trio of Canadian ball carriers in Michael Soles, Blake Marshall and Brian Walling. Pringle spent the rest of 1992 with the Sacramento Surge of the World League of American Football. In 1993, Pringle resurfaced with the CFL's Sacramento Gold Miners, remaining in the same city but switching leagues. In Sacramento, Pringle became an everyday player, although not a frequent option in the ground game that was led by former NFL running back Mike Oliphant. Still he racked up 366 yards and four touchdowns in his only season with the Gold Miners, before being traded in the offseason to the team where he would make his most lasting mark, the then-Baltimore Football Club, later to become the Baltimore Stallions. Baltimore years Going into his third CFL season, Pringle had run the ball 82 times for less than five hundred yards: less than half a season's work for a starting CFL running back. Despite his lack of carries, however, Pringle became the starting back in Baltimore two games into the 1994 season replacing Sheldon Caney. Pringle immediately responded to the opportunity. The 27-year-old went loose in Baltimore, running for a record 1,972 yards and thirteen touchdowns, narrowly missing becoming the first CFL running back to reach the elusive 2,000 yards rushing milestone. He did however set a CFL record with 2,414 yards from scrimmage. He even returned 38 kicks for 814 yards and, in his first CFL playoff appearance, rang up 165 yards in two playoff games to lead Baltimore to their first Grey Cup appearance, where they lost the 82nd Grey Cup to the BC Lions 26-23 on Lui Passaglia's last-minute 38-yard field goal. It is widely heralded as one of the best CFL games ever. Compared to his remarkable 1994 season, 1995 was a slight dropoff for Pringle, but still a remarkable season by any standard. His rushing totals declined to a "mere" 1,791 yards, and while his yards-per-carry fell by .6 from 6.4 to 5.8, his statistics were still the best any back posted in the CFL that year. To top it off, Pringle was a playoff workhorse, as he ran for 484 playoff yards and four touchdowns in three games. On the strong, powerful legs of Pringle, the Baltimore Stallions made their second straight appearance in the Grey Cup. This time, the Stallions would not be denied, taking the famous "Wind Bowl" over the Calgary Stampeders 37-20. After his two seasons in Baltimore, Pringle began to attract more attention from the National Football League. The Denver Broncos signed Pringle to a free agent contract for the 1996 NFL season, but he was a late cut from training camp. Montreal Alouettes With no other NFL teams expressing interest in his abilities, Pringle returned to the CFL, following the relocated Baltimore franchise and joining the newly christened Montreal Alouettes late in the season. Pringle played only eight games but rushed for 825 yards and five touchdowns. It was in 1997 that Pringle once again took his place as the CFL's best running back. His 1,775 yard season was his worst in a full season as a starter, but it was still an extremely strong season. With the Alouettes lacking in playoff success and their attendance at Olympic Stadium flagging, Pringle was one of the team's few bright spots in a disappointing year. But for the 1998 season, the Als moved permanently to the smaller Percival Molson Stadium, where they regularly drew sell-out crowds. They came to watch the Alouettes, especially Pringle, and he would not disappoint. Pringle's 1998 CFL season stands out with Doug Flutie's 48-touchdown 1994 season, as one of the greatest CFL seasons an offensive player ever had. Pringle ran for only nine touchdowns but nobody in the league much cared: the story was his 2,065 rushing yards that year, a CFL record by a considerable margin. Pringle became the first, and so far only, man in CFL history to run for over 2,000 yards. He also tied his CFL record with 2,414 yards from scrimmage. At 31 years old, Pringle had hit his prime with a bang, and though he would never approach 2,000 yards again, he continued to be an elite back for several years. In 1999, Pringle ran for 1,656 yards, over 400 fewer than in his record-shattering 1998. Moreover, playoff failure continued to dog the Alouettes. Pringle had run for 522 yards in his last four playoff games over two seasons, but a disappointing East Division final exit to the eventual champion Hamilton Tiger-Cats had Alouettes fans confused and angry. In 2000, the Alouettes would finally get to play in the 88th Grey Cup but lost to the BC Lions, 28-26. Pringle's rushing totals increased to 1,778 yards, but, more significantly, he rushed for a CFL record 19 touchdowns, a mark almost 50% greater than his previous season high of 13. Pringle also had a touchdown in the Grey Cup game. By the end of the 2001 season, Pringle was 34 years old, an advanced age for a power running back. He was beginning to show wear and tear, as he ran for "only" 1,323 yards in that season while fighting nagging injuries all year. In 2002, the Alouettes would win the 90th Grey Cup over the Edmonton Eskimos 26-16, but Pringle would not be a big part of the game. Pringle was injured much of the year and feuded publicly with head coach Don Matthews, who believed Pringle was washed up and used running back Lawrence Phillips as his starter even when Pringle was healthy. Pringle, incensed at the treatment, left the Alouettes bitterly at the end of the season, signing with the team he had broken in with: the Edmonton Eskimos. Final seasons Pringle's 2003 season with the Eskimos was a return to form for the aging running back. Although he was not the man of 1998, Pringle was still a capable starter for a team on the rise, and with Ricky Ray at quarterback he did not have to be the main part of the team's offense. Pringle ran for 1,376 yards, his best total since 2000, and helped the Eskimos reach, and win, the 91st Grey Cup. Remarkably for a man whose first two seasons were spent largely on the bench, Pringle had George Reed's record 16,116 career rushing yards and 134 career rushing touchdowns well within his sights. Despite his age, most analysts believed Pringle breaking these records was not a matter of if, but when. 2004 proved these analysts right. Pringle ran for 1,141 yards, fourth in the CFL but a career low in a full, starting season. However, the yardage gave Pringle a total of 16,425 rushing yards, as Pringle broke the record in Vancouver, British Columbia against the BC Lions (he had been only a handful of yards short in the previous week's home game against the Calgary Stampeders, but despite receiving the ball on every play on the last few possessions Pringle did not set the mark in front of his home fans). The season ended on some bitterness for Pringle, however. In the last game of the season, the Eskimos were close to the goal line in a tight game. Pringle at the time had 137 touchdowns, tied for Reed's record, and needed only one more to break it. However, head coach Danny Maciocia called a quarterback sneak that resulted in a score, meaning that Pringle finished the season tied with Reed. Pringle was publicly upset with his head coach, and the controversy may have affected the Eskimos in their playoff loss to the Saskatchewan Roughriders. After the 2004 season, Pringle announced his retirement from professional football. He finished with 16,425 career rushing yards and 20,254 total yards from scrimmage, both CFL records. He also finished tied with George Reed with 137 career touchdowns. Pringle led the CFL in rushing yards six time during his career. On June 22, 2005, Pringle signed a contract with the Montreal Alouettes and then officially filed his retirement papers, so that he could retire as an Alouette. His jersey number 27 was retired by the Alouettes at their June 23 season opener. On April 2, 2008, Pringle was inducted into the Canadian Football Hall of Fame. Career regular season rushing statistics References Category:1967 births Category:Living people Category:Sportspeople from Los Angeles Category:Players of American football from California Category:African-American players of Canadian football Category:American football running backs Category:Canadian football running backs Category:Cal State Fullerton Titans football players Category:Atlanta Falcons players Category:Sacramento Surge players Category:Edmonton Eskimos players Category:Sacramento Gold Miners players Category:Montreal Alouettes players Category:Baltimore Stallions players Category:Grey Cup champions Category:Canadian Football League Most Outstanding Player Award winners Category:Canadian Football Hall of Fame inductees
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1. Field of the Invention The invention relates to board games and, more particularly, to a game apparatus having means to control the direction and nature of player movements about a game board. 2. Description of the Prior Art A great number of games employing boards and chance-taking apparatus already are known. In a typical prior game, the board includes indicia indicative of stations to which a player may move a piece controlled by the player. Stations on the board may include directions for performing certain acts, including drawing cards. The cards usually contain yet additional instructions to control the movement of the player's piece. The players sequentially advance their pieces about the board and, generally speaking, the first player to advance his piece to a particular position, or the first player to eliminate other pieces from the board, will be the winner. Although certain prior games have achieved great popularity, people often easily master a particular game and become bored with it. There is a continuing market for games which challenge individuals in new and different ways. A particular challenge which retains universal appeal is that of gambling on the outcome of a particular event or sequence of events. Although games employing chance-taking apparatus by their very nature involve an element of chance, such games generally do not permit the participants to take yet additional chances on the outcome of a particular event. That is, the direction and/or extent of player movements about the board may be determined at random, but players cannot speculate in a meaningful or ordered manner regarding the outcome of a given player's actions.
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War trauma has yet to be receive much attention in the NATO member state of Romania. Cases of psychologically affected soldiers returning home from war zones in Iraq and Afghanistan disappear inside desk drawers and filing cabinets, creating a host of new problems one Bucharest-based psychiatrist has called a “ticking time bomb”. Dr. Gabriel Diaconu is not a fragile person. Tall with broad shoulders, he laughs loudly and often. He often slams his fist down on the table to emphasize a point. He tells stories, eats and smokes cigarettes — often all three at the same time. But as a doctor, discussing the official numbers of cases of post-traumatic stress disorder (PTSD) in the Romanian army make him stop, and a pained expression appears on his face. The trauma specialist is aware of the reality, which the Romanian government and society have largely chosen to ignore. The withdrawal of Romanian troops from Afghanistan has just begun. Since 2002, Romanian soldiers have fought there as a part of NATO’s International Security Assistance Force, or ISAF. From 2003 to 2009, there were also Romanian troops stationed in Iraq. In total, 25 of these soldiers lost their lives in the two wars. In everyday speech, they are known as “heroes”. Many were wounded, and while some of their injuries were visible, others received wounds that remain invisible. But cases of traumatized soldiers returning from war are filed away, and rarely seen or spoken of again. According to official records, only two Romanian soldiers received a diagnosis of PTSD due to their deployment. As approximately 32,000 Romanian troops fought in the wars, that represents a total of just 0.006 percent. Meanwhile, the German Federal Armed Forces reported 149 new cases of PTSD in 2013 alone, with an additional 1274 soldiers were already receiving treatment during the same period. Research at the Technical University of Dresden revealed that three percent of German soldiers met the diagnostic criteria for PTSD after returning home from fighting in operation ISAF. And given that PTSD and other combat-related illnesses often go unreported, that number is likely considerably higher. The American military reports that seven percent of soldiers returning from Afghanistan have symptoms of PTSD. Among troops returning home from Iraq, the military says it’s about 25 percent. Dr. Diaconu is a psychiatrist, and he treats Romanian soldiers who have PTSD. “In my estimation, hundreds must suffer from it”, he says. Diaconu is not an army doctor, meaning his patients have to pay for their therapy themselves. His practice is in Bucharest, which often means he’s hundreds of kilometres away from the people who need his help. One of these people is Florian Jalaboi. He returned home from Afghanistan in 2012. Before that, in the 1990s, he was deployed as a peacekeeper in Bosnia and Herzegovina. The army is his profession, and always has been. But today, Jalaboi can no longer perform his duties, and the Romanian army has granted him early retirement. The fact that Jalaboi cannot continue working due to the debilitating symptoms he experiences as a consequence of PTSD isn’t mentioned anywhere in his discharge papers. As in most other cases, his story will probably be hushed up. Speaking publicly about his disease in the newspaper “Gândul” did not have the desired impact. And Romanian society doesn’t seem to have shown much of a reaction either. Jalaboi, who says he no longer wants to talk to the press, says his “confession” only caused him more trouble. It’s difficult to find an active soldier willing to talk about the inner workings of the Romanian military. “PTSD is not taken seriously,” says one anonymous member of the army. He served for three years in Kosovo and Afghanistan. While he did not develop PTSD, he knows about the problem. “People who get traumatized do not get the necessary support,” he says. After the fall of the Iron curtain, the Romanian military made the difficult transition from a militia to a professional army. It’s one of the few state institutions that can still count on the trust and support of the Romanian population: It stands alone amid the deterioration of political institutions, which have long been associated with corruption and scandals, since Romanian soldiers fight side-by-side with Western armies as equals. Weakness has no place in the image of this poor, but reliable NATO partner. Statements given by members of the Romanian army underline this fact: the Romanian soldier is “healthy, qualified, well prepared and shows no fear,” a military psychologist told the newspaper “Gândul”. Romanian humour is supposed to act as a psychological guard against the cruelties they witness, ruling out the possibility of traumatization. Dr. Diaconu, the psychiatrist in Bucharest, disagrees. He believes the Romanian army demonstrates a “dangerous level of neglect of their own employees”, because there is no place for people suffering from PTSD to go where they can – in his words — “mentally decontaminate themselves”. This fact becomes all the more important given that trauma can also be triggered months after the experience that caused it. For example, injuries sustained in a car accident may suddenly trigger memories of mine explosions. Veterans living with the symptoms of PTSD don’t just lack treatment options. They also may face financial problems. As cases of PTSD are not envisaged in the Romanian army, it does not offer sufferers any professional assistance. A traumatized professional soldier who has to retire from the army may find himself without financial help or employment prospects. Florian Jalaboi was granted a pension that amounts to roughly 150 euros. This is one of the reasons why Dr. Gabriel Diaconu believes traumatized soldiers may return to war. And because the Romanian army refuses to discuss the problem of PTSD publicly, he says it accepts the fact that “time bombs” are released back into civilian life. Liked it? Take a second to support Balkanist on Patreon!
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Q: Sherlock ActionBar Overflow Menu TextColor I am trying to change the textcolor of the overflow menu on my action bar but nothing seems to work <style name="Theme.MyTheme" parent="Theme.Sherlock.Light"> <item name="actionBarStyle">@style/Widget.MyTheme.ActionBar</item> <item name="android:actionBarStyle">@style/Widget.MyTheme.ActionBar</item> <item name="android:popupMenuStyle">@style/MyPopupMenuStyle</item> <item name="actionBarWidgetTheme">@style/MyActionWidgetTheme</item> <item name="android:actionMenuTextColor">@color/title</item> </style> <style name="MyPopupMenuStyle" parent="Widget.Sherlock.Light.ListPopupWindow"> <item name="android:textColor">@color/title</item> <item name="android:textAppearance">@style/TextAppearance.Sherlock.Widget.PopupMenu</item> </style> <style name="TextAppearance.Sherlock.Widget.PopupMenu" parent="Widget"> <item name="android:textColor">@color/title</item> A: Use android:actionBarWidgetTheme <style name="Theme.MyTheme" parent="Theme.Sherlock.Light"> <item name="actionBarStyle">@style/Widget.MyTheme.ActionBar</item> <item name="android:actionBarStyle">@style/Widget.MyTheme.ActionBar</item> <item name="android:actionBarWidgetTheme">@style/MyStyle</item> <item name="actionBarWidgetTheme">@style/MyStyle</item> </style> <style name="MyStyle" parent="Widget"> <item name="android:textColor">#ff0000</item> </style> The above will make the text red.
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1. Field of the Invention The present invention relates to a compressive sensing (CS) approach for reconstructing a signal x(t) that has been randomly and non uniformly sampled and digitized. More specifically, the present invention relates to an approach for reconstructing a signal obtained using a photonic TS ADC in conjunction with non uniform sampling (NUS) using CS techniques. 2. Discussion of the Related Art Digitizing high frequency and/or high bandwidth signals is a desired operation. Apparatus requiring such operations include test and measurement equipment in laboratories, high speed data communications systems, and electronic support measure systems (ESM) that can demonstrate a high probability of intercept (POI), large dynamic range, and good sensitivity over a signal having a wide Instantaneous BandWidth (IBW). Such operations are also applicable to software-defined radio architectures that can unify common back-end digital processing for transceiver operations in e.g. an automobile. A photonic TS ADC (Time-Stretch Analog-to-Digital Converter) can provide continuous time (CT) processing, while delivering a high Effective-Number-Of-Bits (ENOB) of >8 over an IBW of 10 GHz. FIG. 1 is a schematic diagram of a conventional (uniformly sampled) photonic TS ADC system. The system of FIG. 1 implements multiple λ-channels to accomplish signal de-serialization before A/D conversion. The number of parallel λ-channels needed to accomplish CT A/D conversion in such a system is directly proportional to the stretch ratio M, where M=1+D2/D1. In simulations, photonic TS ADC systems with a large stretch-ratio M of M around 41 resulted in a digitized output signal having an effective number of bits (ENOB) that is >8 for an input signal frequency (fsig) of 10 GHz. A large stretch ratio (M) is important to producing a high ENOB. However, a TS ADC system constructed with a stretch ratio of 41 may require a large number of parallel channels to accomplish continuous time (CT) operation. Specifically, the number of parallel ADC-channels required to form a CT TS ADC system is directly proportional to M as illustrated in FIG. 1. FIG. 2 is a schematic diagram of an ADC system termed a random demodulator (RD) described in a document from Tropp et al, entitled “Beyond Nyquist: Efficient Sampling of Sparse Bandlimited Signals”, IEEE Transactions on Information Theory, Vol. 56, No. 1, 2010”; for the compressive sensing of a wideband analog input-signal. In FIG. 2, an input signal f(t) is coupled to a first input terminal of a mixer 302, and a pseudorandom generator 304 is coupled to a second input terminal of the mixer 302. An input terminal of the pseudorandom generator 304 is coupled to a source of a seed value for controlling the pseudorandom sequence. An output terminal of the mixer 302 is coupled to an input terminal of an integrator 306. An output terminal of the integrator 306 is coupled to an input terminal of a sampler 308, where the components 306 and 308 behave the same way as a standard ADC. An output terminal of the analog-to-digital converter 306-308 generates a sampled digital output signal y[n]. To permit signal reconstruction via use of compressive sensing (CS), the analog input signal f(t) is assumed to be a frequency-sparse signal. As illustrated in FIG. 2, a pseudo-random chip-sequence pc(t) from pseudorandom generator 304, switched at a rate W between random amplitudes of ±1, is mixed in mixer 302 with the analog input signal f(t). The mixed signal is fed to integrator 306. The output of integrator 306 provides a randomized projection (i.e., a randomized linear combination) of the mixed product of f(t) and pc(t) over an integration time-interval of 1/R, where R is the clock rate of the cascaded ADC chip. Because the chip-rate of pc(t) is W, W/R randomized chips are mixed together (via integration) to form the input of a sampler chip 308 that follows the integrator 306 (the “chip-sequence” being the pseudorandom code-sequence pc(t) (typically ±1) generated by the Pseudorandom Generator in the figure and the chip-rate being the number of pulses/sec at which the code is generated.). It is to be noted that although there are Md row-elements in the “measured” output, each row-element is obtained, after integration, over successive sampling time-intervals nTs. The sampler 308 chip is clocked uniformly at a rate R. As detailed hereafter, CS based techniques are used to calculate sparse Fourier coefficients (‘a’ω of [a]) of f(t) from the measured output of the ADC 306, 308. As detailed in the Tropp et al. document, compressive sensing (CS) techniques can use a matrix form model of the random demodulator (RD) of FIG. 2. FIG. 3 is a matrix diagram illustrating a CS matrix formalism representing the RD system architecture depicted in FIG. 2. CS based techniques can be used to calculate sparse Fourier coefficients (“a′ω” of [a]) of f(t) from the measured output of the ADC. The input signal xn is eventually recovered via use of a W×W DFT that transforms the sparse vector (denoted [a] in FIG. 3) back to the time-domain. The compression ratio of this random demodulation scheme is given by W/R. Because the sampling rate R of the ADC-chip can be much lower than the Nyquist sampling rate of the input signal f(t), the CS compression ratio of a RD can be >10. For example, an input harmonic signal f(t) at 800 kHz may be recovered from ADC measurements that are clocked at 100 kHz, which was 1/16 the Nyquist sampling rate fN. The mixing of pc(t) and f(t) may randomize the amplitudes of the input signal (at the chip rate W) in the RD approach, and the sensing bandwidth of a RD architecture may be limited by that of the mixer. FIG. 4 is a schematic diagram of an all-electronic approach for implementing NUS via use of a S/H and Pseudo Random Bit (PSRB) timing generator, such as described for example in a document from M. Wakin, et al, entitled “A Non-Uniform Sampler for Wideband Spectrally-Sparse Environments”, to be published in JESTCS”. In FIG. 4, a signal input terminal of a main sample-and-hold (MSH) circuit 502 is coupled to a source of an analog input signal Ain. An output terminal of the MSH circuit 502 is coupled to a signal input terminal of a subsampling sample and hold (SSH) circuit 504. An output terminal of the SSH circuit 504 produces an analog output signal Aout and is coupled to a signal input terminal of an analog-to-digital converter (ADC) 508. An output terminal of the ADC 508 generates a digital output signal Dout. A first input terminal of a timing generator 506 is coupled to a source of a clock signal Cin, and a second input terminal of the timing generator 506 is coupled to a source of a sampling clock signal Nin. A first output terminal of the timing generator 506 is coupled to a timing input terminal of the MSH circuit 502; a second output terminal of the timing generator 506 is coupled to a timing input terminal of the subsampling S/H 504; and a third output terminal of the timing generator 506 is coupled to a timing input terminal of the ADC 508. One skilled in the art understands that other elements may be necessary for the proper operation of the system illustrated in FIG. 4, such as buffer amplifiers. The skilled practitioner will understand what those elements are, where they should be located, and how to design and build those elements. One skilled in the art further understands that the ADC 508 may be implemented by a commercial off-the-shelf component. In operation, the analog input signal Ain is a frequency fsig having a bandwidth of around 0.8-2 GHz. This signal is digitized by subsampling randomly at an average rate (fs)AV of 0.236 GHz. The input signal is reconstructed from the ADC 508 output via use of compressive sensing techniques. The all-electronic NUS approach illustrated in FIG. 4 is implemented with a sample/hold (S/H) frontend, i.e. the main sample and hold MSH circuit 502, samples the input signal Ain at the Nyquist rate or higher. Samples are then randomly discarded, e.g. keeping on the average of one of every 19 samples, by the SSH 504 in response to a synchronized pseudo-random bit (PSRB) sequence from the timing generator 506 to simulate randomized NUS. It is noted that the system of FIG. 4 is implemented with a Nyquist rate S/H, i.e. MSH 502, and it would be difficult to scale to a signal with a wider IBW without incurring clock jitter issues. In addition, the chip also uses on-grid A/D conversion, making it difficult to obtain performance advantages. Improvements may therefore be made over the conventional systems discussed above. More specifically, an ADC system which can produce a digital representation of a frequency sparse signal which may have a wide instantaneous bandwidth, while maintaining a suitable of equivalent number of bits with a minimum of circuitry, is desirable. A CT ADC system using CS techniques designed with reduced channel count may decrease data-throughput along with simplified hardware construction. This, in turn, may facilitate the deployment of digital channelized receivers, reduce costs, and produce improved computational results.
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GOP rivals gang up on Newt Gingrich in Iowa debate DES MOINES, Iowa — Republicans threw everything they could at Newt Gingrich in a fiery debate Saturday night, increasingly desperate to stop his momentum toward the 2012 presidential nomination in the final weeks before voting starts in less than 4 weeks. The former speaker of the House of Representatives responded with a combination of laughs and a steely determination not to let the charges go unanswered, particularly from chief rival Mitt Romney. The spirited, two-hour debate was the first since Gingrich shot to the lead in polls in Iowa, prompting a round of challenges to his record as a Washington insider, his well-paid consulting work for the semi-federal mortgage agency Freddie Mac, his marital infidelities, and his recent statement that the Palestinians are an "invented" people. "Speaker Gingrich has been in government for a long time... I spent my life in the private sector. I understand how the economy works," Romney said in an early criticism of the longtime politician. "Let's be candid," Gingrich fired back. "The only reason you didn't become a career politician is because you lost to Teddy Kennedy in 1994," he said, when Romney lost a Senate bid. "You'd have been a 17-year career politician by now if you'd won." Romney tried to turn that notion around. "If I would have been able to get into the NFL (National Football League) like I wanted to when I was a kid, I'd have been a football star...losing to Teddy Kennedy was probably the best thing I could have done for the job I'm seeking," he said. "It put me back in the private sector." That got applause. Rep. Michele Bachmann of Minnesota hit Gingrich as a Washington elitist, noting acidly that he's made more than $100 million since leaving Congress, some of it in consulting fees from the Freddie Mac housing agency that conservatives want to dismantle. "When you're talking about taking over $100 million, and when your office is on the Rodeo Drive of Washington D.C., which is K Street, and you're taking money to influence the outcome of legislation in Washington, that's the epitome of the establishment, that's the epitome of a consummate insider," said Bachmann. Gingrich chafed at the criticism, insisting that he was just making a living. "I was in the private sector," he said. "And when you're in the private sector, and you have a company and you offer advice...you're allowed to charge money for it....It's called free enterprise." Some also challenged Gingrich's recent statement that the Palestinians are an "invented" people. "That's just stirring up trouble," said Rep. Ron Paul of Texas. "That was a mistake," said Romney, adding that he would never make such an inflammatory statement. "I will exercise sobriety," he said, implicitly suggesting that Gingrich acts rashly. "I'm not a bomb thrower, rhetorically or literally." "These people are terrorists," responded Gingrich, in reference to Palestinians. "Sometimes it's helpful to have a president of the United States who tells the truth." He likened his statement to Ronald Reagan calling the Soviet Union an "evil empire." The candidates also talked about the importance of marriage vows, a clear slap at Gingrich, who is in his third marriage. Every other candidate is married to their first spouse. "If you cheat on your wife, you'll cheat on your business partner," said Texas Gov. Rick Perry, who said his marriage vow was made not only to his wife, but to God. "Character issues do count," said former Sen. Rick Santorum of Pennsylvania. "I would not say it's a disqualifier ...but certainly it's a factor...trust is everything." Gingrich conceded that "it is a real issue" and that candidates and voters have a right to ask. "In my case," he said, "I've made mistakes at times. I've had to go to God for forgiveness." Bachmann slammed both Gingrich and Romney for supporting government mandates that people buy health insurance, supporting "cap and trade" environmental legislation, the $700 billion TARP bank bailout, and an extension of the payroll tax cut. She referred to them as "Newt Romney." Gingrich reacted sternly. "Michele, a lot of what you say just isn't true, period." Romney was more jocular, protesting her tying the two together. "I know Newt Gingrich and Newt Gingrich is a friend of mine, but we are not clones," he said to laughter. It was the 12th debate of the campaign, held at Drake University and broadcast by ABC. The candidates will debate again Thursday in Iowa, the last debate before Iowa Republicans kick off the voting with precinct caucuses on Jan. 3. While the first 11 GOP debates in this campaign drew decent ratings, the holiday Saturday night airtime faced a challenge drawing viewers. The manager of the local ABC affiliate said the network chose the date because it was the first Saturday all fall that was free from either a televised NASCAR or college sporting event; ABC usually
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Q: TinyMCE links aren't including href Solved! The initial problem: I'm using TinyMCE for a text editor. Right now, I just have the default plugins applied. It appears that 'autolink' is one of those, as it turned a link into an 'a' tag. The problem I'm having is that it's not giving the 'a' tag an href. I tried applying the 'link' plugin, but it's giving me the same problem. It creates blue, underlined text in the form of an 'a' tag, but omits any kind of href. How can I get this to work correctly? I'm running on a Windows computer in Chrome, though I tried it in Microsoft Edge just to see if that did anything and it didn't. This was my initial configuration, copy-pasted form their website. <script>tinymce.init({selector: 'textarea'})</script> This is my most recent configuration. It's formed from a combination of a codepen I found and a few things I've tried. <script>tinymce.init({ selector: 'textarea', theme: 'modern', plugins: [ 'advlist autolink lists link image charmap print preview hr anchor pagebreak', 'searchreplace wordcount visualblocks visualchars code fullscreen', 'insertdatetime media nonbreaking save table contextmenu directionality', 'emoticons template paste textcolor colorpicker textpattern imagetools codesample toc help' ], toolbar1: 'undo redo | insert | styleselect | bold italic | alignleft aligncenter alignright alignjustify | bullist numlist outdent indent | link image', toolbar2: 'print preview media | forecolor backcolor emoticons | codesample help', image_advtab: true, templates: [ { title: 'Test template 1', content: 'Test 1' }, { title: 'Test template 2', content: 'Test 2' } ], relative_urls : true, remove_script_host : false });</script> Solution: I tried a different rich text editor to see if that would help and it was doing the same thing. After a little more digging, I found that express-sanitizer was the culprit. A: The problem was that I was sanitizing my hrefs (and probably a bunch of other stuff) out on the server. If you come across this, check your sanitizer.
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Herbal tea Herbal teas—less commonly called tisanes (UK and US , US also )—are beverages made from the infusion or decoction of herbs, spices, or other plant material in hot water. The term "herbal tea" is often used in contrast to true teas (e.g., black, green, white, yellow, oolong), which are prepared from the cured leaves of the tea plant, Camellia sinensis. Besides coffee and true teas (they are also available decaffeinated), most other tisanes do not contain caffeine. History Camellia sinesis, the tea plant, has been grown for around 5000 years. The plant is a member of the family Theaceae, its origins dating back to China and Southeast Asia. According to ancient Chinese legend, the drink was made accidentally by King Shen Nong (around 2700 b.c.e). Despite the legend, it is documented that the Chinese have been using herbal tea as a medicine dating back to around 2000 years ago. The habitual consumption of tea grew in Asia and eventually European explorers brought it home to Europe in the 17th century. Herbal tea then became a staple in British and Irish culture during that time. Tea is widely consumed all over the world today. Etymology Some feel that the term tisane is more correct than herbal tea or that the latter is even misleading, but most dictionaries record that the word tea is also used to refer to other plants beside the tea plant and to beverages made from these other plants. In any case, the term herbal tea is very well established and much more common than tisane. The word tisane was rare in its modern sense before the 20th century, when it was borrowed in the modern sense from French. (This is why some people feel it should be pronounced as in French, but the original English pronunciation continues to be more common in US English and especially in UK English). The word had already existed in late Middle English in the sense of "medicinal drink" and had already been borrowed from French (Old French). The Old French word came from the Latin word ptisana, which came from the Ancient Greek word πτισάνη (ptisánē), which meant "peeled" barley, in other words pearl barley, and a drink made from this that is similar to modern barley water. Health risks While most herbal teas are safe for regular consumption, some herbs have toxic or allergenic effects. Among the greatest causes of concern are: Comfrey, which contains alkaloids which may be harmful to the liver from chronic use, and particularly is not recommended during pregnancy or when prescription drugs are used; comfrey is not recommended for oral use. Lobelia, which contains alkaloids and has traditional medicine uses for smoking cessation, may cause nausea, vomiting, or dizziness at high doses. Herbal teas can also have different effects from person to person, and this is further compounded by the problem of potential misidentification. The deadly foxglove, for example, can be mistaken for the much more benign (but still relatively toxic to the liver) comfrey. The US does not require herbal teas to have any evidence concerning their efficacy, but does treat them technically as food products and require that they be safe for consumption. Fruit or fruit-flavored tea is usually acidic and thus may contribute to erosion of tooth enamel. Contamination Depending on the source of the herbal ingredients, herbal teas, like any crop, may be contaminated with pesticides or heavy metals. According to Naithani & Kakkar (2004), "all herbal preparations should be checked for toxic chemical residues to allay consumer fears of exposure to known neuro-toxicant pesticides and to aid in promoting global acceptance of these products". During pregnancy In addition to the issues mentioned above which are toxic to all people, several medicinal herbs are considered abortifacients, and if consumed by a pregnant woman could cause miscarriage. These include common ingredients like nutmeg, mace, papaya, bitter melon, verbena, saffron, slippery elm, and possibly pomegranate. It also includes more obscure herbs, like mugwort, rue, pennyroyal, wild carrot, blue cohosh, tansy, and savin. Composition Herbal teas can be made with fresh or dried flowers, fruit, leaves, seeds or roots. They are made by pouring boiling water over the plant parts and letting them steep for a few minutes. The herbal tea is then strained, sweetened if desired, and served. Many companies produce herbal tea bags for such infusions. Major varieties While varieties of tisanes can be made from any edible plant material, below is a list of those commonly used for such: Anise tea, made from either the seeds or the leaves Asiatic penny-wort leaf, in South Asia and Southeast Asia Artichoke tea Bael Fruit tea, utilized for its antibacterial properties which can be effective in treating diarrhea, dysentery, ulcers, as well as respiratory infections. Bee Balm Boldo, used in South America Burdock, the seeds, leaves, and roots have been used to increase blood circulation and treat skin disorders in addition to some cancers, diabetes, and AIDS Cannabis tea, used in the preparation of Bhang Caraway, tea made from the seeds Catnip, tea used as a relaxant, sedative, and to calm Chamomile, commonly used for sore stomach, irritable bowel syndrome, and as a gentle sleep aid. It is also used as a mild laxative and is anti-inflammatory and bactericidal. Che Dang, very bitter tea made from Ilex causue leaves Chinese knot-weed tea Chrysanthemum tea, made from dried flowers, is popular with Chinese Dim sum Cinnamon Coca tea, infusion made from coca leaves. Contains trace amounts of cocaine and similar alkaloids. In some countries where coca is illegal, products marketed as "coca tea" are supposed to be decocainized, i.e., the pharmacologically active components have been removed from the leaf using the same chemicals used in manufacturing cocaine. Cacao bean tea Coffee-leaf tea, coffee fruit tea, and coffee blossom tea are herbal teas made using the leaves, fruits and flowers of the coffee plant Coffee bean tea, or simply coffee, a tisane made from the seeds of the coffee plant Cerasse, bitter Jamaican herb Citrus peel, including bergamot, lemon and orange peel Dandelion coffee Dill tea Dried lime tea, made from dried limes, is popular in western Asia Echinacea tea Elderberry European Mistletoe (Viscum album), (steep in cold water for 2–6 hours) Essiac tea, blended herbal tea Fennel Gentian Ginger root, can be made into herbal tea, known in the Philippines as salabat Ginseng, popular tea in China and Korea, commonly used as a stimulant and as a caffeine substitute. Goji, popular and very simple to prepare tea Hawthorn Hibiscus (often blended with rose hip), a popular tea alternative in the Middle East which is drunk hot or cold. Hibiscus tea is also consumed in Okinawa, and used in Chinese and Ayurvedic medicine (see Hibiscus health benefits). It is also used in Roselle (see below.) Honeybush, similar to rooibos and grows in a nearby area of South Africa, but tastes slightly sweeter. Has a low tannin content, no caffeine. Horehound Houttuynia Hydrangea tea, dried leaves of hydrangeas; considerable care must be taken because most species contain a toxin. The "safe" hydrangeas belong to the Hydrangea serrata Amacha ("sweet tea") Cultivar Group. Jiaogulan, (also known as xiancao or poor man's ginseng) Kapor tea, dried leaves of fireweed Kava root, from the South Pacific, commonly used for its effects in promoting talkativeness and relaxation. As well, kava extracts may be an effective alternative to tricyclic antidepressants and benzodiazepines for the treatment of anxiety disorders. Kratom, dried leaves of the Kratom tree, drank for its medicinal and stimulant effects. Kuzuyu, is a thick white Japanese tea made by adding kudzu flour to hot water Labrador tea, made from the shrub by the same name, found in the northern part of North America. Lemon Balm Lemon and ginger tea Lemon grass Luo han guo Licorice root Lime blossom, dried flowers of lime tree (Tilia in Latin). Mint, especially peppermint (also mixed with green tea to make mint tea) Moringa Mountain Tea, a very popular tea in the Balkans and other areas of the Mediterranean region. Made from a variety of the Sideritis syriaca plant which grows in warm climates above 3,000 feet. Records of its use date back 2,000 years. Neem leaf Nettle leaf New Jersey Tea Noni tea Oksusu cha, traditional roasted corn tea found in Korea. Olive leaf tea Osmanthus tea, dried flowers of the sweet olive tree are used alone or blended with tea leaves in China. Pandan Tea Patchouli tea Pennyroyal leaf, an abortifacient Pine tea, or tallstrunt, made from needles of pine trees Poppy tea, drank for its sedative and analgesic properties Qishr, Yemeni drink with coffee husks and ginger Red clover tea Red raspberry leaf Barley tea, East Asian drink with roasted barley Roasted wheat, used in Postum, a coffee substitute Rooibos (Red Bush), reddish plant used to make an infusion and grown in South Africa. In the US it is sometimes called red tea. It has many of the antioxidant characteristics of green tea, but because it does not come from tea leaves, it has no caffeine. Rose hip (often blended with hibiscus) Roselle petals (species of Hibiscus; aka Bissap, Dah, etc.), consumed in the Sahel and elsewhere Rosemary Sagebrush, California Sagebrush Sage Sakurayu, Japanese herbal tea made with pickled cherry blossom petals Salvia Sassafras roots were steeped to make tea and were used in the flavoring of root beer until being banned by the FDA. Scorched rice, known as hyeonmi cha in Korea Skullcap Serendib (tea), tea from Sri Lanka Sobacha Spicebush (Lindera benzoin) leaves used to make a tea by some native peoples of eastern North America Spruce tea, made from needles of spruce trees Staghorn sumac, fruit can be made into a lemonade Stevia, can be used to make herbal tea, or as a sweetener in other beverages St. John's Wort Thyme, contains thymol, an antiseptic used in mouthwashes such as Listerine. Tulsi, or Holy Basil, in English Turmeric tea Uncaria tomentosa, commonly known as Cat's Claw Valerian is used as a sedative. Verbena (Vervain) Vetiver Wax gourd in East Asia and Southeast Asia. Wong Lo Kat, recipe for herbal tea from Guangdong, China since the Qing Dynasty Woodruff Yarrow See also Health food store List of hot beverages Tea culture Tincture, the often more concentrated plant extracts made in pure grain alcohol, glycerin, or vinegar Traditional Chinese medicine References External links hu:Gyümölcstea
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# Set the warning/log level to 3 -W3 # output grf -ftr #bitmap mode -gb # Set the bit depth to 4 (16 colors) -gB4 #The Transperant colour of 0xFF00FF -gT FF00FF ################## # Old Parameters #-W3 # disable alpha and set opaque bit for all pixels #-gT! # use lz77 compression #-gzl # 16 bit bitmap #-gB16 ##################
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Arthur Percy Noyes Arthur Percy Noyes, M.D. (1880-1963) was a physician, psychiatric hospital administrator and medical educator, In his career he published a number of textbooks and articles that relate to the modernization of psychiatric practices, outpatient care and the need for life-long education for medical staff. He was born in Enfield, New Hampshire, of Puritan stock who emigrated to the American colonies from England in 1633. His early education was in a one-room schoolhouse and later at the Kimball Union Academy in Meriden, New Hampshire. He entered Dartmouth College in 1899 and worked his way through college by teaching in rural areas. After his college graduation in 1902, he entered the University of Pennsylvania medical school. He graduated in 1906. He interned for one year at the City Hospital in New York City and then spent several years in general practice in New York and Connecticut. Noyes returned to Philadelphia for one year of graduate study in internal medicine and neurology, and then entered the field of psychiatry at the Boston Psychopathic Hospital. From 1916 to 1920, he was an assistant physician and executive officer at the hospital. In 1920, Noyes moved to Washington, D.C., to join the medical staff at the St. Elizabeths Hospital. He served under William A. White, the superintendent, who was a leader in psychiatry and in the administration of psychiatric hospitals. In 1929, Noyes moved to Rhode Island to become the superintendent of the state's mental hospital. He stayed until 1936 when he moved to the state mental hospital in Norristown, Pennsylvania, where he remained for 19 years until he retired. He had a productive tenure at these hospitals: modernizing the facilities, developing teaching curricula for medical students from the University of Pennsylvania and the Jefferson Medical School. He is also credited with creating a psychiatric residency training programs which last for over fifty years. Noyes wrote A Textbook on Psychiatry for Students and Graduates in Schools of Nursing in 1936. Noyes's teaching activities led to publication of his textbook Modern Clinical Psychiatry. His textbook was widely used in medical schools when it was first published in 1934. He was president of the Philadelphia Psychiatric Society and the Pennsylvania Psychiatric Society. At the American Psychiatric Association, he served on the Committees of Nursing Standards and Policies, the Council, the Executive Committee, and as president from 1954 to 1955. His Presidential Address stressed the importance of studying the humanities in psychiatric education. Select Works and Publications Noyes, Arthur Percy. A Textbook of Psychiatry for Students and Graduates in Schools of Nursing. New York, Macmillan, 1927 Noyes, Arthur Percy. Modern Clinical Psychiatry. Philadelphia: W.B. Saunders, 1934 Noyes, Arthur Percy. A Textbook of Psychiatry. New York, Macmillan, 1936 References Bookhammer, Robert S. "Arthur Percy Noyes, M.D., President, 1954-1955: A Biographical Sketch," American Journal of Psychiatry 112 (1 July 1955): 8-10 External links Category:1880 births Category:1963 deaths Category:American psychiatrists Category:People from Enfield, New Hampshire Category:Physicians from New Hampshire Category:Dartmouth College alumni Category:Perelman School of Medicine at the University of Pennsylvania alumni Category:American Psychiatric Association Category:Textbook writers
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Q: If li has ul inside <ul> <li> <ul></ul> </li> <li></li> <li></li> <li></li> <li> <ul></ul> </li> </ul> How do I add class="parent" only for li, which has ul inside it? A: You can use :has() in your selector, like this: $("li:has(ul)").addClass("parent")
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This world health day, celebrated on 7^th^ April, the World Health Organization (WHO) has brought food safety to the centre stage with the theme 'Food safety - from farm to plate, make food safe'. This is a call for increased attention to food safety and its potential impact on public health, food security, and food trade competitiveness of countries[@ref1]. From the days of policies working towards sheer food security as a solution to the problems of malnutrition to broad basing them to take cognizance of nutrition security, food safety was always considered an addendum to nutrition[@ref2]. Today, in the context of the challenges posed by the changing patterns of food production, distribution and consumption in the increasingly globalizing economies such as ours, food safety has come to be top on priority[@ref3]. Now is the time nutrition is integrated inextricably with food safety and both should be seen as integral parts of nutrition as well as food safety promotion policies and programmes. Given the background of the current nutritional problems in India, we propose that the scope of food safety or the term safe food should be expanded to include what we call 'nutrition safety'. Here we also argue why India needs a more culture and context sensitive perspective for ensuring food safety. Defining nutritionally safe {#sec1-1} =========================== Nutrition safety is hard to define. But given the fact that there is sufficient evidence to link high consumption of energy-dense food to rising rates of obesity and associated non-communicable diseases, the terms High fat, salt and sugar (HFSS) and nutrient-poor food are commonly used to characterize foods perceived as unhealthy[@ref4][@ref5] and to distinguish these from more nutritious options. However, it is not always the individual food that is healthy or unhealthy but it is the overall diet and the activity pattern of the population that decides this. Nutrient poor food items are largely those found at the top of the Food Pyramid of Indian Dietary Guidelines[@ref6]. These are called nutritionally unsafe just because these are recommended to be consumed 'sparingly'. Today, the food systems have undergone considerable changes and physical activity among population has lowered. All of these pose serious threat to nutrition safety, worsening the dual burden of malnutrition. There are increasing demands for restricting certain foods usually considered energy-dense and nutrient poor. This calls for making a distinction between nutrient-dense foods and discretionary calories as suggested by the Dietary Guidelines for Americans - 2005[@ref7]. Discretionary calories could be consumed later, in proportion to energy needs. The recent guidelines also suggested that by selecting the nutrient-dense food first, consumers will meet the recommended nutrient intakes without exceeding their energy allowance[@ref8]. However, compared to the West, consumer awareness on monitoring nutrient quality of food is minimal in countries like India. Creating a healthy retail and sales environment through policy changes can lead to changes in the food ecosystem. An attempt to promote not only safe but healthy food choices is being attempted through the food labelling regulation of the Food Safety and Standards Authority of India (FSSAI), which mandates that nutrition and ingredients related information is provided to the consumer alongside safety information like best-before/use-by date, storage instructions, allergens, quality symbols, *etc*[@ref9]. Food safety - The need to revisit {#sec1-2} ================================= While the regulatory and administrative framework taken up by FSSAI since 2006, is critically important for ensuring that safe food is made available to the consumers, food safety should not be constructed as an attribute reliant on producers, retailers, handlers and regulators. Positioning them thus makes these concerns concentrate mostly on the 'supply side' of food safety from food production to distribution. Food safety is determined not only by how food is produced and delivered, but also by issues on the 'demand side' - how consumers acquire, cook, store, and consume food. Food safety cannot be ensured only with stricter regulation, compliance with global standards of manufacturing, distribution and competitiveness. There is a need to consider behavioural, structural and cultural issues along the continuum of food from farm to plate and then to consumption[@ref10]. The 'five keys for safer food' campaign of WHO is being used to spread the food hygiene message among the food manufacturers and handlers throughout the world. This campaign promotes personal hygiene, adequate cooking, avoiding cross-contamination, keeping food at safe temperatures, and avoiding food from unsafe sources[@ref11]. Such campaigns may however, result in limited protection unless food safety is also understood and promoted at the household level. In India, diverse food habits, hygiene practices and centuries-old traditions co-exist alongside the changes introduced by globalization. In addition, the scarcity of resources at the household level make food safety promotion a daunting public health task. Food-borne illnesses continue to be prevalent; a nation-wide study in 2006 revealed that about 13 per cent of households reported food-borne illnesses in the previous fortnight (of the survey)[@ref12]. Such routine food-borne illnesses may relate to a host of practices at individual and household levels, including behaviours pertaining to how food is procured (what quantity/quality and from whom), stored (for example, without refrigeration), prepared (household processing, extent of cooking, fuel used, *etc*.), and consumed (without washing hands, freshly cooked or reheated). These are, in turn, influenced not only by cultural factors (like cooking practices) but also by structural (like availability of safe fuel, clean water, *etc*.) and individual factors (*e.g*. people\'s knowledge and beliefs)[@ref10]. Unlike many western countries, in India, semi-processed primary agricultural produce and raw materials are procured from the market before these are further processed and made suitable for cooking at home. In this situation, adulteration becomes a major food safety concern. Adulteration may be intentional or unintentional. In both forms, the quality or the nature of the food is altered and may even become harmful[@ref13]. This problem is sufficiently normalized that most people do not consider it to be a health hazard, and there is little drive on the part of the public to resist deliberate adulteration[@ref14]. In addition, a relative lack of public awareness of existing food regulations has further accentuated the problems. As only a small percentage of Indian homes own refrigerators, the campaigns about cross-contamination, reheating, or thawing tend to be of limited relevance. Even without powered refrigeration, many Indians practice indigenous ways of storing leftover foods. It is also common to cook as and when required in small quantities to avoid storage[@ref14][@ref15]. The safety implications of commonly employed food storage and consumption practices need to be better understood so that the associated risks could be effectively communicated and feasible alternatives encouraged. Hand washing, a behaviour closely linked with food safety, is relatively routine in India, and it is often customary to wash hands before handling food[@ref12]. Approximately 75 per cent of individuals wash hands only with water and often do not use soap. Even after defecation, only 50 per cent use soap when washing hands[@ref12][@ref14]. Usage of soap can reduce the risk of diarrhoeal diseases by 42-47 per cent[@ref16]. The customary practice of hand washing can be strengthened by encouraging routine and universal access and use of soap for hand washing. One of the common threats to food safety is inadequate cooking. This may not, however, pose as large a threat to food safety in India, as in other countries. Food in India is generally cooked and served hot. This cultural practice can be strengthened with education regarding the scientific basis for thorough heating rather than simple warming[@ref14]. In India, with an estimated 37 per cent of Indians living in poverty, most homes do not have a separate designated kitchen, such that living, cooking and eating occur in a common place[@ref12][@ref17]. Availability of safe drinking water is an important factor that affects food safety. For many episodes of diarrhoeal diseases among adults and the estimated 3,00,000 deaths among children (\< 5 yr), lack of protected water supply was an important reason apart from other factors such as sanitation and environmental conditions[@ref18]. The way forward {#sec1-3} =============== Many food safety challenges faced by people in India need multi-dimensional approach. In order to motivate self-directed changes in practices at individual or household level, people need to be given not only the scientific rationale to alter the established food related practices but also the means and resources to practice the safe ones. Food safety policies and programmes should aim to address the entire farm-to-plate-to-consumption continuum using culturally sensitive and adaptive approaches. Creating evidence and popularizing intelligent food synergies is required to overcome the dueling effects of malnutrition and food safety. [^1]: This editorial is published on the occasion of World Health Day - April 7, 2015.
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Occurrence of multidrug resistant Salmonella in antimicrobial-free (ABF) swine production systems. This cross-sectional study was conducted to determine the prevalence and antimicrobial resistance of Salmonella species in swine reared in the intensive (indoor) and extensive (outdoor) ABF production systems at farm and slaughter in North Carolina, U.S.A. We sampled a total of 279 pigs at farm (extensive 107; intensive 172) and collected 274 carcass swabs (extensive 124; intensive 150) at slaughter. Salmonella species were tested for their susceptibility against 12 antimicrobial agents using the Kirby-Bauer disk diffusion method. Serogrouping was done using polyvalent and group specific antisera. A total of 400 salmonellae were isolated in this study with a significantly higher Salmonella prevalence from the intensive (30%) than the extensive farms (0.9%) (P<0.001). At slaughter, significantly higher Salmonella was isolated at the pre- and post-evisceration stages from extensively (29% pre-evisceration and 33.3% post-evisceration) than the intensively (2% pre-evisceration and 6% post-evisceration) reared swine (P<0.001). The isolates were clustered in six serogroups including B, C, E1, E4, G and R. Highest frequency of antimicrobial resistance was observed against tetracycline (78.5%) and streptomycin (31.5%). A total of 13 antimicrobial resistance patterns were observed including the pentaresistant strains with ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, tetracycline resistance pattern observed only among isolates from the intensive farms (n=28) and all were serotype Salmonella typhimurium var. Copenhagen. In conclusion, this study shows that multidrug resistant Salmonella are prevalent in ABF production systems despite the absence of antimicrobial selection pressure. In addition, it also highlights the possible role played by slaughterhouse and other environmental factors in the contamination and dissemination of antimicrobial resistant Salmonella in ABF production systems.
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Q: Was the name for the Shōwa era a voluntary pun? According to dictionaries, the WA 和 in 昭和 has both the meaning of peace, harmonious and Japan, japanese (although mostly as the first kanji of a compound, such as in 和語). So I wonder how Japanese of those times perceived the announcement and the phrase. Did it carry immediately a meaning of (luminous) Peace for Japan, or was the national or identity element not present for a native speaker? A: Whether the emperor meant it as a "pun" (or something similar) is pretty hard to know. But it is doubtful. 昭和 means harmony for the same reason that 和 is associated to Japan: in both cases, 和 represents the very specifically-Japanese conception of "social harmony" (which is different enough from the western word, for many scholars to use "Wa", even in English texts). It is not a coincidence, but it predates our era by a good 13 centuries. The use of 和 in the spelling of 大和【やまと】(old name for Japan) has a long and complex history, but the gist of it is that it was picked as a replacement for a previous kanji used by the Chinese (倭), which the Japanese did not find flattering. 和 did have a positive association with a philosophical concept that the Japanese considered at the heart of their culture, hence the entanglement and how it became to be both "harmony" and "japan". To answer your question of whether it carried a meaning of Harmony specifically for Japan: yes, in a way, since "Wa" is the Japanese conception of harmony, and foreigners (particularly of this era) would definitely not be expected to grasp its meaning, let alone have it.
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R Markdown – Dynamic documents, presentations and reports for R - michaelsbradley http://rmarkdown.rstudio.com/ ====== minimaxir R Markdown is very powerful. That being said, I still find myself using Jupyter notebooks instead due to first-class language kernel support of non-R languages (which was not the case at Rmarkdown's launch, when Jupyter was still IPython), and GitHub integration for rendering notebooks. The dynamic aspect of Rmarkdown is done through HTMLWidgets, which also works with Jupyter notebooks too. (But not via the GitHub integration mentioned earlier.) ~~~ nicolewhite I've almost fully switched from Jupyter to RMarkdown after discovering RMarkdown supports Python. And about publishing / rendering, do you not like RPubs? ~~~ geomark As well as a number of other rather useful languages [1]. Now days I use RMarkdown even for experiments because it's nice to document my line of thinking as I write the code and get a nicely formatted output when I'm finished. [1] [http://yihui.name/knitr/demo/engines/](http://yihui.name/knitr/demo/engines/) ------ mistercow This sounds a lot like how literature coffeescript works.
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Lindsey Stirling releases deluxe edition of ‘Warmer in the Winter’ Acclaimed violinist and artist Lindsey Stirling has released a deluxe version of her 2017 Christmas album Warmer in the Winter. The new repackaged version of the album includes five additional tracks, such as ‘I Wonder as I Wander’, ‘Santa Baby’ and ‘Hallelujah’. A Target exclusive version is also available which includes an extra two offerings, ‘Mary Did You Know’ and ‘Home For The Holidays’. ‘Time to Fall in Love’ featuring Alex Gaskarth of All Time Low (original) ‘Jingle Bell Rock’ ‘Silent Night’ Bonus Tracks: ‘I Wonder As I Wander’ ‘We Three Gentlemen’ (Medley of “We Three Kings”, “God Rest Ye Merry Gentlemen” and “Carol Of The Bells”) ‘Santa Baby’ ‘Main Title from Home Alone (Somewhere in My Memory)’ ‘Hallelujah’ 2018 Target Super Deluxe Edition Bonus Tracks Include: ‘Mary Did You Know’ ‘Home For the Holidays’ Alongside the deluxe edition of the album, Lindsey has also unveiled a music video for ‘I Wonder as I Wander’. Switching between a beach setting at sunset and a snow filled winter scene, the stunning visual sees Lindsey passionately singing and playing the violin. The visual and its striking changing backdrops add a dramatic and powerful element to proceedings, which works perfectly for the song. Check out the visual for ‘I Wonder as I Wander’ below. To coincide with the release of the deluxe edition of Warmer in the Winter, Lindsey will be heading out on The Wanderland Tour. Kicking off in Reno, NV on November 23, the tour will stop off at numerous cities including New York, Philadelphia, and Washington DC. The tour will feature a “fully revamped stage production with elaborate Holiday themes, as well as, Stirling’s signature brand of dance routines and on-stage visuals”. * Buffalo, NY is a benefit show for the Ronald McDonald House and there is no club/VIP pre-sale available. For full ticket information, head to Lindsey’s website. A range of VIP and meet and greet packages are also available, including an invitation to Lindsey’s Christmas Workshop. Click here for more information on VIP packages. Warmer in the Winter (Deluxe Edition) is available to purchase or stream now. Are you feeling in the festive spirit thanks to Lindsey Stirling and her deluxe edition of Warmer in the Winter? Let us know on Twitter @CelebMix
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Q: Is there a better way to finish the activity from another activity? I have 3 activities FirstActivity, SecondActivity and ThirdActivity. FirstActivity leads to SecondActivity which leads to ThirdActivity. I would like to be able to move back and forth between FirstActivity and SecondActivity , FirstActivity and ThirdActivity. Here is what I have implemented : FirstActivity : In FirstActivity I have an onClick method 'goToSecondActivity', which starts SecondActivity public void goToSecondActivity(View view){ Intent i = new Intent(this, SecondActivity.class); final EditText firstText = (EditText) findViewById(R.id.firstText); String userMessage = firstText.getText().toString(); if(!"".equals(userMessage)) i.putExtra("firstMessage",userMessage); startActivity(i); } SecondActivity : In SecondActivity again I have an onClick method 'goToThirdActivity', which starts ThirdActivity public void goToThirdActivity(View view){ Intent i = new Intent(this , ThirdActivity.class); startActivity(i); } ThirdActivity : In ThirdActivity I have two onClick method 'backToFirstActivity' and 'backToPreviousActivity' on two different buttons On ThirdActivity when I click On 'Back To First Activity' button , I want to go back to the FirstActivity. What I have Done : SecondActivity : I have declared static variable static SecondActivity secondActivityMain; And assign it in onCreate method : protected void onCreate(Bundle savedInstanceState) { --- --- secondActivityMain = this; --- --- } ThirdActivity : Using static variable finishes the SecondActivity "SecondActivity.secondActivityMain.finish();" public void backToFirstActivity(View view) { Toast.makeText(getApplicationContext(), "Third: finished second activity ", Toast.LENGTH_SHORT).show(); new Handler().postDelayed(new Runnable() { @Override public void run() { SecondActivity.secondActivityMain.finish(); ThirdActivity.this.finish(); } }, 2000); } My Questions Are : 1. Is there a better way to finish the activity from another activity? 2. Is this way is correct? A: If you want to go FirstActivity from ThirdActivity use this this intent with flag "FLAG_ACTIVITY_CLEAR_TOP" it will clear Third and second Activity Intent intent = new Intent(ThirdActivity.this, MainActivity.class); intent.addFlags(Intent.FLAG_ACTIVITY_CLEAR_TOP); startActivity(intent); For FirstActivity In Manifeast file if you are specified android:launchMode="singleTop" then OnCreate() method will not be called when you are came from ThirdActivity to FirstActivity if you are not specified lanuhMode in manifeast file then OnCreate will be called Again A: Is there a better way to finish the activity from another activity? Yes, What you have done is used static instace on Activity which could easily lead to memory leak issues. Its always good practice to use static keyword only if necessary and very carefully as well. Better way would use BroadCastreceiver So, what you need to do is create broadcast receiver in your first and second activity and whenver you wants to finish those activity. use sendBroadCast(..) method. you need to search it out how Broadcastreceiver works in android. Is this way is correct? No, The way you did is not correct.
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Pines Trail at Pembrey Forest0300 065 3000workWalking RouteThe Pines trail is a circular walk that starts at Pembrey Country Park Visitor Centre, turning right from the beach path to follow the wide, straight woodland ride. The walk is very well waymarked and can be done with or without the accompanying leaflet that is available from the Visitor Centre.PembreyNr Burry PortSA16 0EJUnited Kingdom51.682147182500-4.296221821670http://www.showmewales.co.uk/southwestwales Pines Trail at Pembrey Forest Walking Route, free entry Pembrey Forest Pembrey Forest Details The Pines trail is a circular walk that starts at Pembrey Country Park Visitor Centre, turning right from the beach path to follow the wide, straight woodland ride. The walk is very well waymarked and can be done with or without the accompanying leaflet that is available from the Visitor Centre. Access: Pembrey Country Park Visitor Centre Duration: 2Hours Miles: 4 Occasionally the site is closed in extreme weather, such as high winds or snow and ice due to the risk of injury to visitors or to undertake maintenance work or forest operations. Please always follow any instructions onsite and make sure you follow any temporary diversion signs in place. Contact Address Location Directions By Car: Follow signs to Pembrey Country Park from the A484 road on the Kidwelly side of Pembrey, near Burry Port. Continue from the Park entrance to the Visitor Centre car park. There is a charge at the park entrance. Pembrey is the nearest town or village. Parking: free Nearby Facilities Children welcome Dogs accepted Occasionally the site is closed in extreme weather, such as high winds or snow and ice due to the risk of injury to visitors or to undertake maintenance work or forest operations. Please always follow any instructions onsite and make sure you follow any temporary diversion signs in place.
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Disney's "Frozen" has been a phenomenon. It's been in the top 10 at the box office for 16 straight weeks, bringing in over $1 billion worldwide. It won two Academy Awards, including Best Animated Feature. And it has been analyzed and picked apart by its fans. We've already looked at some of the "easter eggs" hidden in the film — including a Mickey Mouse doll and a cameo from Rapunzel — but there's one more subtle reference few have ever noticed. In fact, even the person it's based on wasn't told about it. [Related: Play 'Frozen' Find-It With Our Exclusive Guide to Film's Easter Eggs] The song "Love Is an Open Door," which you can see in its entirety above exclusively here on Yahoo Movies, contains a brief moment where Prince Hans, belting out a high note under a waterfall, closes his eyes and raises his arm in an exact copy of a signature move by '70s singing sensation Donny Osmond. And it was put there by a Disney animator who just happens to be Osmond's nephew. View photos Hyrum Osmond is a Disney veteran who has been animating features at the studio since 2008's "Bolt." On "Frozen," he was the supervising animator for Olaf, the lovable snowman, but he stepped in to animate Prince Hans for that one particular moment. In a phone conversation with Yahoo Movies, Osmond said, "I requested that shot, just because I knew that that was the perfect moment to kind of pepper in that Donny Osmond feel to it." After all, the song between Hans and Princess Anna is the kind of bubblegum pop number that made the Osmonds famous. Hyrum's father is George Virl Osmond Jr., the eldest of Donny's seven brothers, who was born with a hearing impairment and did not perform on stage with his siblings. But he did work behind the scenes, and Hyrum said he spent time watching his uncle and aunt Marie working on their variety show. "Obviously we were exposed to the 'Donny and Marie' show. We were on set a lot," Hyrum said. "And me and my brothers and sisters almost playfully mocked our uncles with their signature move, which was basically sort of a tilted head, eyes squinting, with the raising of their arm or arms as they belt out that note." So when it was time for Hans to hit his high note, the younger Osmond wanted to pay tribute to that move: "I just thought it was a perfect moment to kind of hit the Donny Osmond pose there." View photos
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Eating for health & testing my taste buds one bite at a time… Holiday festivities… and food! Hi everyone! I hope y’all had a fun and relaxing weekend. Jeff and I started a serious journey towards finding out perfect home this weekend and let me tell you…. STRESSFUL. I don’t know if I ever pictured house hunting to be this stressful, but boy do I see why we have avoided it until now. With that said, yesterday I was in dire need of a little relaxation and down time. Jeff worked through the afternoon, which gave me time to plan a nice little Memorial Day dinner for both of us. No, I didn’t pull out the grill (although I’d highly recommend it if you make the burgers!) because sitting in front of a hot grill in 100 degree weather just didn’t seem all that appealing. When it comes to festive foods, you know I like to keep it simple, flavorful, and fun! I had been thinking about making sliders for a while so I went with mini turkey burger sliders as our main dish and a unique, tangy “potato salad” for our side. Who doesn’t love burgers and potato salad?! The potato salad is definitely not your traditional potato salad. I added a little roasted corn and sauteed green beans for added color and flavor. The dressing is super delicious, tangy, and easy to make. It can also be used to marinate chicken, other meats, or dress other salads/veggies! Make it ahead of time to save yourself some extra work if planning for a party or barbecue! For the turkey burgers, I decided to do a few sliders wrapped in romaine lettuce for myself and mini buns for Jeff. I like the added crunch of the lettuce and found this to be a great alternative to a regular bun if you tend to eat gluten-free or want to minimize your carbs for other health reasons. The burgers were flavored with green chile and shredded cheddar cheese, nut other flavor combos such as feta and basil or blue cheese and bacon would also be great to try! I hope you give these recipes a try and maybe add them in to your next barbecue. The 4th of July is right around the corner, so planning ahead will help minimize stress and hopefully lead to a fun and relaxing party! Directions In a large bowl, mix all ingredients with hands or roughly with a fork. Roll and press patties about the size of a larger, thick cookie or muffin top. Place on parchment paper until ready to cook. In a large pan (or on a grill), spray the surface to prevent sticking. Heat the pan to medium heat and place about 4-5 patties in the pan. Cook about 4-5 minutes on each side or until juices run clear and there is a golden brown color on the surface. Serve with toppings of choice.
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Q: impute missing values using minimum of a class in R I'm new to R and need help with imputing missing values in one of the columns in a dataset that I'm currently working on. The below image shows the missing value I want to impute along with few of the columns. I want to fill in the value with the minimum qty for a customer using its previous entries as I think this best fits my situation and data. For example, in the image I should be able to fill in the missing value with 1 (min of 1,5,2). During my search, I mainly came across methods that use mean for a given class, and not minimum or maximum. Any help or pointers would really be appreciated. Edit: Here is the output from dput. structure(list(YEAR = c(2011L, 2012L, 2014L, 2015L, 2011L, 2012L ), CustomerId = c("00000063", "00000063", "00000063", "00000063", "00000065", "00000065"), MemberType = structure(c(2L, 2L, 2L, 2L, 2L, 2L), .Label = c("GROUP", "INDIVIDUAL", "PARTNER"), class = "factor"), MembershipTypeCode = structure(c(6L, 6L, 6L, 10L, 6L, 6L), .Label = c("EGROUP", "EINDIV", "EINDIV2", "EPARTNER", "GROUP", "INDIV", "INDIV2", "INDIV3", "PARTNER", "PLUS", "PLUS2", "PLUS20", "PLUS3", "PLUSENTERPRI", "PLUSGROUP", "PLUSGROUP2", "PROF_ENTERPR", "PROF_GROUP", "PROF_GROUP2", "PROF_INDIV", "PROF_INDIV2", "PROF_INDIV3"), class = "factor"), MembershipPeriodBegin = structure(c(15279, 15677, 16071, 16436, 15006, 15371), class = "Date"), MembershipPeriodEnd = structure(c(15644, 16070, 16435, 16800, 15370, 15736), class = "Date"), ConsecutiveYearsAsMember = c(14L, 15L, 17L, 18L, 8L, 9L), AllocationUsage = c(0, 0, 0, 0, 0, 0), SetCOPPreference = structure(c(2L, 2L, 2L, 2L, 2L, 2L ), .Label = c("Y", "N"), class = "factor"), Purchase.Qty = c(2L, 5L, 1L, NA, 7L, 27L), Webcast.Registration = c(0L, 0L, 0L, 0L, 0L, 1L), Web.Visits = c(0L, 0L, 42L, 0L, 0L, 0L), Web.Page.Views = c(0L, 0L, 98L, 0L, 0L, 0L), Blog.Visits = c(0L, 0L, 3L, 0L, 0L, 0L), Blog.Page.Views = c(0L, 0L, 4L, 0L, 0L, 0L), Forum.Visits = c(0L, 0L, 45L, 0L, 0L, 0L), Forum.Page.Views = c(0L, 0L, 102L, 0L, 0L, 0L), ParatureTickets = c(0L, 0L, 0L, 0L, 0L, 0L), ParatureChats = c(0L, 0L, 0L, 0L, 0L, 0L), Registered.for.Edu = c(0L, 0L, 0L, 0L, 0L, 0L), Attended.ICE = structure(c(2L, 2L, 2L, 2L, 2L, 2L), .Label = c("Y", "N"), class = "factor"), Attended.TK = structure(c(2L, 2L, 2L, 2L, 2L, 2L), .Label = c("Y", "N"), class = "factor"), Frugal = structure(c(2L, 2L, 2L, 2L, 2L, 2L), .Label = c("Y", "N"), class = "factor"), Chapter.Board = structure(c(2L, 2L, 2L, 2L, 2L, 2L), .Label = c("Y", "N"), class = "factor"), Retained = structure(c(5L, 5L, 5L, 1L, 5L, 5L), .Label = c("Active", "Awaiting Renewal", "Future Dated", "Lost", "Retained"), class = "factor"), ProfileCompletion = c(60, 60, 60, 60, 60, 60), NumberofLogins = c(1L, 1L, 15L, 0L, 0L, 4L), Downloads = c(NA_integer_, NA_integer_, NA_integer_, NA_integer_, NA_integer_, NA_integer_), ForumMember = structure(c(NA_integer_, NA_integer_, NA_integer_, NA_integer_, NA_integer_, NA_integer_ ), .Label = "N", class = "factor"), FreeUpgrade = structure(c(1L, 1L, 1L, 1L, 1L, 1L), .Label = c("Y", "N"), class = "factor")), .Names = c("YEAR", "CustomerId", "MemberType", "MembershipTypeCode", "MembershipPeriodBegin", "MembershipPeriodEnd", "ConsecutiveYearsAsMember", "AllocationUsage", "SetCOPPreference", "Purchase.Qty", "Webcast.Registration", "Web.Visits", "Web.Page.Views", "Blog.Visits", "Blog.Page.Views", "Forum.Visits", "Forum.Page.Views", "ParatureTickets", "ParatureChats", "Registered.for.Edu", "Attended.ICE", "Attended.TK", "Frugal", "Chapter.Board", "Retained", "ProfileCompletion", "NumberofLogins", "Downloads", "ForumMember", "FreeUpgrade"), row.names = c(NA, 6L), class = "data.frame") Thanks, Pratik A: Since you provide no data, here a toy example how I would do it in base R: # simple sample data data <- data.frame( a = rep( 10:12, each = 4 ), b = 12:1 ) data[ c( 3, 5, 12 ), 2 ] <- NA # for each unique a value, get the row index with the min b value, # and write that min value to col b where b is NA for( i in unique( data$a ) ) data[ which( is.na( data$b ) & data$a == i ), "b" ] <- min( data[ data$a == i, "b" ], na.rm = TRUE ) data a b 1 10 12 2 10 11 3 10 9 4 10 9 5 11 5 6 11 7 7 11 6 8 11 5 9 12 4 10 12 3 11 12 2 12 12 2
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Money & Banking Prince Harry’s $35 million fortune under threat It has come to light that Prince Harry’s $35 million trust fund, set up for him by his late mother Princess Diana and the Queen Mother, could be targeted for tax reasons thanks to a US legal loophole. Despite Harry and Meghan marrying in May this year, the new Duchess of Sussex is still technically a US citizen. While it’s believed she has officially applied to become a British citizen, apparently – even though she is a royal now – her application process doesn’t receive any special treatment and could take several years before she is granted UK citizenship. Which means, in the meantime, the former actress is legally required to pay US income tax on any earnings or allowances she receives whilst residing in Britain. But now that she is married to Prince Harry, it could mean his own earnings could be affected too. Royal aides speaking to the Sunday Express in the UK, stated, “We’re looking at a level of financial exposure the royal family has never had to face before.” They added, “It’s the royal household’s worst nightmare … Everything has to be declared.” Along with Meghan’s own $7 million fortune she amassed during her acting career, British media has reported that the US taxman could also have his eye on her designer clothes, jewellery, homes and gifts the new Duchess has received as royal proceeds. The Duke of Sussex lives off his $35 million trust fund inheritance, earning an annual salary of around $525,000 a year. But the US government could potentially count that towards Meghan’s income in the UK too. Do you think Harry and Meghan should have to pay US tax on their royal earnings? Share your thoughts in the comments below.
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We have seen so far how the exchange interaction between localized electrons spins leads to ferromagnetism and other form of magnetic ordering as a result of the Dirac Isenberg exchange interaction. But of course, this is somewhat not our going to limited interest, because we know that the well-known ferromagnets do not have localized spins. Namely the ferromagnetic metals, such as iron, cobalt and nickel are metals with delocalized, not localized electrons. So in order to account for the ferromagnetic ordering in these metals, it is necessary to consider exchange interaction between itinerant or conduction electrons in a d band metals. We can use the same concept that we consider for the exchange interaction between a pair of electrons and build in the idea of the electron wave function for itinerant electron. So we can write the effective wave function for such a pair of electrons i and j as one by root two V e to the power i k i r i e to the power i k j dot r j minus e to the power i k i dot r j e to the power i k j dot r i. This is the positions at r i and r j, the electrons at r i and r j and wave vector k and k i and k j. Now this is the exchange because of the in disguise visibility of the electrons this is the exchanged term and the two electron wave function should be anti-symmetry with respect to the spatial part in order to give raise to a ferromagnetic or spin parallel wave function. So rewriting this, we can write this as into one minus… Therefore, psi i j square, mod psi i j square dr i dr j will be from this, we can easily see that this will have the form taking r i minus r i j as the separation r between the two electrons. We can now write the probability for two spin being parallel, two electrons spin being parallel, and being separated as just this. Now this should be multiplied by d r here, and this will giving you n up. Where n up is the number of electrons spins. In this spin up sign band which is equal to n by 2, so that using this we can write this exchange charge density as by multiplying the electronic charge and… We take this average, this dash, this dash over this form – bracketed term is just the average, now we average over the Fermi sphere, so that we have rho exchange over r as. So that would be the form of this exchange charge density. Now to this of course, we must add the charge density e n by 2 due to anti parallel plus the charge density, due to anti parallel spin. Doing this, we finally arrive at the effective charge density as… So that would be the form of the effective charge. And this is shown in the form of a plot of this effective charge normalized by e n versus as a function of k F r and that shows so called the exchange hole. This means that the presence of the exchange interaction leads to a situation where the effective charge density is reduced because of this exchange correlation. So this leads to a renormalization of the electron energies, which is the stating points of the Hahree -Fock approximation. We will not go into details of this, but use this idea to discuss the so called band model of ferromagnetism. This was first proposed by Stoner and Wohlfarth, effectively that means that the energy of the electrons in the spin up band and in the spin down band can be written as basic original energy minus I into n up divided by N, and this is minus I down by N. Where N is of course, n up plus n down that is the total number of electrons, and I is the Stoner parameter, which describes the energy reduction due to electron correlation. We define a parameter R which is n up minus n down by N. So this is the difference between the number of electrons with up and down spins and therefore, this should be proportional to the magnetization. In order to put this electron energy, which we have written in a slightly more transparent form, we redefine the zero of energy with respect to by subtracting. I times n up plus n down by 2 N, so subtract, this from the energy. And redefine the energy, so we denote this by e tilt minus I R by 2. This can be easily verified and similarly e down turns out to be given by… Where e tilt of k equals e of k minus this quantity. So starting with these, these are the renormalized electrons sub band energies and our aim is to calculate the magnetization, which is proportional to parameter R. So we can write R as 1 by N sigma f up k minus f down k the summation over, all k values, where f k is the Fermi Dirac distribution function which we have discussed already. So substituting for this, R turns out to be one by N sigma over K writing the actual form of the Fermi Dirac distribution function and substituting for e up and e down values the energies. So this will be e minus e tilt minus e F minus I R by 2 by k B T, because there is a negative sign there plus 1 minus 1 by… So we simplify this by noting that we have a function f of X minus delta x here, and the function with f of X plus delta x. So this is given because of the exponential, we can write this as plus higher order term involving delta x cube into f x by 3 factorial etcetera. So using this, and applying it to this, we get the parameter R as 1 by N sigma K d f k by d e k times I R, neglecting the other terms, which is necessarily positive, the times f dash. So this is we know the Fermi Dirac distribution function has a negative sign here, whereas the next term involving the third order derivative is positive. So if we want a positive magnetization, a non-zero magnetization, which means that R should be positive. We arrive at the Stoner criterion for ferromagnetism, we can see readily from this, this criterion to be… This will have a maximum value at t equal to 0, and it will have a particularly simple form at absolute 0. So you will evaluate this at absolute 0 over the summation can be written as… And we know this is going to give you a delta function, therefore, we can simplify this as… So that would become, where D of e f is the electron density of states of the Fermi energy. So from this, we get Stoner criterion as… And we can redefine V by 2 N D of E F as some D tilt of E F, in which case we get particularly compact form for this Stoner criterion for ferromagnet. Now this has been calculated, the electronic density of states at the Fermi level for the various metal have been calculated and using these values, the product I times D tilt of E F can be calculated and that is shown in the picture. And it can be seen that the Stoner criterion is fulfilled only for iron, cobalt and nickel, so that is a very remarkable result predicting ferromagnetism according to the simple Stoner criterion in D band metals namely iron, cobalt and nickel, which are well-known to be metallic ferromagnets. So that is how this simple Stoner model accounts for ferromagnetism in these metals. Now the next question is what happens in an external magnetic field. It is quite simple and straight forward, so this Stoner parameter the R becomes… Where this is the two mu B B is the Zeeman splitting in the presence of the applied magnetic field. So instead of I R, it becomes I R plus two mu B B and the magnetization is nothing but N by V times R. So that can be written straight a way in the form, so the magnetization therefore we get the magnetization is given in this form in the presence of an applied field. Therefore, we can define the susceptibility as the ratio between M and B which is given by, so it has the form chi 0 by 1 minus I times D tilt e F, so this is known as an enhancement factor, this is called a Stoner enhancement of the magnetic susceptibility. So this is the Stoner enhancement factor, which increases the magnetic susceptibility. Next, we would like to calculate the spontaneous magnetization and its temperature dependence. You know to calculate this, we assume a delta function behavior for the electron density of states, D electron density of states at the Fermi energy. In order to keep the calculation simple and with that assumption, we get the parameter R as we have same as before exponential mu B B naught minus I R by 2 plus 1 minus 1 by exponential mu B B naught plus I R by 2 plus 1. We set to bring it to a simpler form, we make the following substitution, we set T c, a parameter T c as I and mu B effective by mu B into 4 k B. We also take R tilt as mu B effective by mu B times R, so that in terms of this, the R tilt becomes simply 1 by exponential two R T c by T plus 1 minus… This shows the correct behavior, this tends to equals to 1 for T equal to 0 and equal to 0 for T equal to T c. So T c defined in this way is the Curie temperature of this ferromagnet. In addition for T very small compared to T c, it is well below the Curie temperature, this R tilt is given by 1 minus 2 e to the power minus 2 T c by T. And the neighborhood of T c, this is given by root three times 1 minus T by T c. So this gives a number of things to compare with experiment, the figure shows the factor parameter R tilt as the function of T by T c. So this is the near the critical temperature, the expected behavior according to this model is root 3 times 1 minus T by T c to the power half, giving rise to a so called a critical exponent of half. But what is experimentally observed is one-thirds has can be seen from the next figure. So the critical exponent magnetization goes as one minus T by T c to the power one-thirds in the neighborhood of the critical temperature, so there is a strong deviation in the critical behavior at the ferromagnetic Curie temperature. Also the low temperature behavior, there is considerable deviation of the experimental results data points from the expected theoretical curve. So these are due to the shortcomings of the Stoner model, especially that gives Stoner model does not take proper account of the excited states. Because in addition to spin flips, a cumbering the excitation from band to another, other element excitation with a smaller quantum of energy or possible and they can also cause spin flip. This is not taken into account in the Stoner model. Now for T above the Curie temperature, T greater than T c, we can expand the exponentials and write R as mu B by 2 K B T into B naught plus T c by T into R, so that is leads to a susceptibility which goes as C by T minus T c. And this we can readily recognizes as the Curie Weiss behavior. So in short, we have described in terms of the simple Stoner model, how one can account for ferromagnetism in a d-band metal, such as iron, cobalt and nickel and how this leads to features, which predict the correct Curie Weiss behavior and also leads to a Stoner enhancement of the susceptibility. The temperature dependence of the spontaneous magnetization of course you have the correct overall behavior for the order parameter namely the magnetization, but the critical behavior as well as the low temperature behavior are not very well described by Stoner model, because of the improper treatment of the excited states. So with we have some idea of how band of model of ferromagnetism can be used to describe magnetic ordering in metals. With this we conclude our discussion of magnetism.
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Characterization and 3D correction of geometric distortion in low-field open-magnet MRI. In this paper, we present a method to characterize and correct geometric image distortion in 0.2 T MR images. A large 3D phantom with spherical balls was used to characterize geometric distortion on an AIRIS Mate 0.2 T MR Scanner (Hitachi). MR images of the phantom were acquired in axial, sagittal and coronal planes using 2D Fast Spin Echo (FSE) sequence and distortions were measured at each control point. Two piecewise interpolation methods were then applied to correct geometric distortion. Distortion was characterized and corrected in any axial, sagittal or coronal slice within an effective FOV of 330(LR) x 180(AP) x 210(HF) mm(3). The distortion was reduced from 16 mm to 1.2 mm at 180 mm from the magnet center. A fast and accurate method for correction of geometric distortion was performed within large distances from the magnet isocenter.
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