|
--- |
|
annotations_creators: |
|
- expert-generated |
|
language: |
|
- en |
|
language_creators: |
|
- expert-generated |
|
license: |
|
- apache-2.0 |
|
multilinguality: |
|
- monolingual |
|
pretty_name: clinical_trial_reason_to_stop |
|
size_categories: |
|
- 1K<n<10K |
|
source_datasets: |
|
- original |
|
tags: |
|
- bio |
|
- research papers |
|
- clinical trial |
|
- drug development |
|
task_categories: |
|
- text-classification |
|
task_ids: |
|
- multi-class-classification |
|
- multi-label-classification |
|
--- |
|
|
|
# Dataset Card for Clinical Trials's Reason to Stop |
|
|
|
## Table of Contents |
|
- [Table of Contents](#table-of-contents) |
|
- [Dataset Description](#dataset-description) |
|
- [Dataset Summary](#dataset-summary) |
|
- [Supported Tasks and Leaderboards](#supported-tasks-and-leaderboards) |
|
- [Languages](#languages) |
|
- [Dataset Structure](#dataset-structure) |
|
- [Data Instances](#data-instances) |
|
- [Data Fields](#data-fields) |
|
- [Data Splits](#data-splits) |
|
- [Dataset Creation](#dataset-creation) |
|
- [Curation Rationale](#curation-rationale) |
|
- [Source Data](#source-data) |
|
- [Annotations](#annotations) |
|
- [Personal and Sensitive Information](#personal-and-sensitive-information) |
|
- [Considerations for Using the Data](#considerations-for-using-the-data) |
|
- [Social Impact of Dataset](#social-impact-of-dataset) |
|
- [Discussion of Biases](#discussion-of-biases) |
|
- [Other Known Limitations](#other-known-limitations) |
|
- [Additional Information](#additional-information) |
|
- [Dataset Curators](#dataset-curators) |
|
- [Licensing Information](#licensing-information) |
|
- [Citation Information](#citation-information) |
|
- [Contributions](#contributions) |
|
|
|
## Dataset Description |
|
|
|
- **Homepage:** https://www.opentargets.org |
|
- **Repository:** https://github.com/LesyaR/stopReasons |
|
- **Paper:** |
|
- **Point of Contact:** data@opentargets.org |
|
|
|
### Dataset Summary |
|
|
|
This dataset contains a curated classification of more than 5000 reasons why a clinical trial has suffered an early stop. |
|
The text has been extracted from clinicaltrials.gov, the largest resource of clinical trial information. The text has been curated by members of the Open Targets organisation, a project aimed at providing data relevant to drug development. |
|
|
|
All 17 possible classes have been carefully defined: |
|
- Business_Administrative |
|
- Another_Study |
|
- Negative |
|
- Study_Design |
|
- Invalid_Reason |
|
- Ethical_Reason |
|
- Insufficient_Data |
|
- Insufficient_Enrollment |
|
- Study_Staff_Moved |
|
- Endpoint_Met |
|
- Regulatory |
|
- Logistics_Resources |
|
- Safety_Sideeffects |
|
- No_Context |
|
- Success |
|
- Interim_Analysis |
|
- Covid19 |
|
|
|
### Supported Tasks and Leaderboards |
|
|
|
Multi class classification |
|
|
|
### Languages |
|
|
|
English |
|
|
|
## Dataset Structure |
|
|
|
### Data Instances |
|
|
|
```json |
|
{'text': 'Due to company decision to focus resources on a larger, controlled study in this patient population."', |
|
'label': 'Another_Study'} |
|
``` |
|
|
|
|
|
### Data Fields |
|
|
|
`text`: contains the reason for the CT early stop |
|
`label`: contains one of the 17 defined classes |
|
|
|
### Data Splits |
|
|
|
[More Information Needed] |
|
|
|
## Dataset Creation |
|
|
|
### Curation Rationale |
|
|
|
[More Information Needed] |
|
|
|
### Source Data |
|
|
|
#### Initial Data Collection and Normalization |
|
|
|
[More Information Needed] |
|
|
|
#### Who are the source language producers? |
|
|
|
[More Information Needed] |
|
|
|
### Annotations |
|
|
|
#### Annotation process |
|
|
|
[More Information Needed] |
|
|
|
#### Who are the annotators? |
|
|
|
[More Information Needed] |
|
|
|
### Personal and Sensitive Information |
|
|
|
[More Information Needed] |
|
|
|
## Considerations for Using the Data |
|
|
|
### Social Impact of Dataset |
|
|
|
[More Information Needed] |
|
|
|
### Discussion of Biases |
|
|
|
[More Information Needed] |
|
|
|
### Other Known Limitations |
|
|
|
[More Information Needed] |
|
|
|
## Additional Information |
|
|
|
### Dataset Curators |
|
|
|
[More Information Needed] |
|
|
|
### Licensing Information |
|
|
|
This dataset has an Apache 2.0 license. |
|
|
|
### Citation Information |
|
|
|
[More Information Needed] |
|
|
|
### Contributions |
|
|
|
Thanks to [@ireneisdoomed](https://github.com/<github-username>) for adding this dataset. |