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10,983,941 | Postnasal maturation of the human endolymphatic sac. | The Laryngoscope | Laryngoscope | 110 | 9 | 10.1097/00005537-200009000-00008 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE/HYPOTHESIS] The objective of this study was to trace the postnatal development of the human endolymphatic sac. The endolymphatic sac starts as a pouch-like structure during the fetal period in the human but later develops into a complex network of tubules in its mature form. [STUDY DESIGN] Observational stud... | null | 1.349 | 183 | Otorhinolaryngology | Medicine | 2,000 |
10,983,645 | Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine. | AIDS (London, England) | AIDS | 14 | 11 | 10.1097/00002030-200007280-00014 | eng | 2,000 | 7 | 28 | null | null | null | [OBJECTIVE] To assess the HIV-1-RNA response and drug concentrations in cerebrospinal fluid (CSF) and serum during treatment with saquinavir (SQV)/ritonavir (RTV) or SQV/RTV plus stavudine (d4T) in HIV-1 -infected patients. [DESIGN] A multicentre, open-label, randomized controlled trial. [METHODS] A total of 208 protea... | null | 3.611 | 233 | Immunology; Immunology and Allergy; Infectious Diseases | Immunology and Microbiology; Medicine | 2,000 |
10,983,209 | Autoimmune diseases: a leading cause of death among young and middle-aged women in the United States. | American journal of public health | Am J Public Health | 90 | 9 | 10.2105/ajph.90.9.1463 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVES] This study assessed the effect of autoimmune diseases on mortality among women. [METHODS] Counts of autoimmune disease deaths were compared with frequencies of the 10 "official" leading causes of death among women in the United States in 1995. [RESULTS] Autoimmune disease deaths exceeded the frequency of t... | null | 2.126 | 321 | Public Health, Environmental and Occupational Health | Medicine | 2,000 |
10,982,571 | Can anti-smoking television advertising affect smoking behaviour? controlled trial of the Health Education Authority for England's anti-smoking TV campaign. | Tobacco control | Tob Control | 9 | 3 | 10.1136/tc.9.3.273 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVES] To evaluate the effectiveness of the Health Education Authority for England's anti-smoking television advertising campaign in motivating smokers to give up and preventing relapse in those who had already given up. [DESIGN] A prospective, controlled trial was conducted in four TV regions in central and nort... | null | 0.931 | 147 | Health; Public Health, Environmental and Occupational Health | Medicine; Social Sciences | 2,000 |
10,982,541 | Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men. | Circulation | Circulation | 102 | 11 | 10.1161/01.cir.102.11.1264 | eng | 2,000 | 9 | 12 | null | null | null | [BACKGROUND] Recent evidence supports differential effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the 2 major omega3 fatty acids of marine origin, on blood pressure in humans and vascular reactivity in adult spontaneously hypertensive rats. We investigated possible differences in the effects of ... | null | 5.669 | 691 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,000 |
10,980,772 | Design of a magnetically integrated microporous implant. | Archives of ophthalmology (Chicago, Ill. : 1960) | Arch Ophthalmol | 118 | 9 | 10.1001/archopht.118.9.1259 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To determine the orbital tolerance of a microporous implant fitted with an integrated stainless steel post and the enhanced motility associated with magnetic coupling of the prosthetic and the implant in a rabbit model. [METHODS] Six New Zealand white rabbits underwent primary enucleation with implantation ... | null | null | null | null | null | null |
10,979,349 | Carbohydrate malabsorption and the effect of dietary restriction on symptoms of irritable bowel syndrome and functional bowel complaints. | The Israel Medical Association journal : IMAJ | Isr Med Assoc J | 2 | 8 | null | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Carbohydrate malabsorption of lactose, fructose and sorbitol has already been described in normal volunteers and in patients with functional bowel complaints including irritable bowel syndrome. Elimination of the offending sugar(s) should result in clinical improvement. [OBJECTIVE] To examine the importanc... | null | null | null | null | null | null |
10,979,060 | Montelukast, a leukotriene receptor antagonist, in combination with loratadine, a histamine receptor antagonist, in the treatment of chronic asthma. | Archives of internal medicine | Arch Intern Med | 160 | 16 | 10.1001/archinte.160.16.2481 | eng | 2,000 | 9 | 11 | null | null | null | [BACKGROUND] Montelukast sodium, a potent, oral, specific leukotriene-receptor antagonist, has demonstrated clinical efficacy in the treatment of chronic asthma. Loratadine, a selective histamine type 1 (H(1))-receptor antagonist, has demonstrated antiallergic properties. Leukotriene-receptor antagonists given concomit... | null | null | null | null | null | null |
10,978,040 | Cerebral infarction in adult AIDS patients: observations from the Edinburgh HIV Autopsy Cohort. | Stroke | Stroke | 31 | 9 | 10.1161/01.str.31.9.2117 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND AND PURPOSE] Autopsy series of patients with AIDS have found a 4% to 29% prevalence of cerebral infarction. Little is known of the prevalence of cerebral infarction when not associated with non-HIV central nervous system (CNS) infection, lymphoma, or cardioembolic sources. Clinical correlation has seldom be... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,977,035 | Cardiovascular autonomic function is associated with (micro-)albuminuria in elderly Caucasian sujects with impaired glucose tolerance or type 2 diabetes: the Hoorn Study. | Diabetes care | Diabetes Care | 23 | 9 | 10.2337/diacare.23.9.1369 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To determine whether impaired cardiovascular autonomic function correlates with albuminuria in an age-, sex-, and glucose tolerance-stratified sample of an elderly (50-75 years of age) Caucasian population and to determine whether this association is independent of other determinants of albuminuria. [RESEAR... | null | 2.422 | 433 | Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine; Nursing | 2,000 |
10,977,026 | Personality correlates of glycemic control in type 2 diabetes. | Diabetes care | Diabetes Care | 23 | 9 | 10.2337/diacare.23.9.1321 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To determine whether traits of normal personality are associated with variations in glycemic control in patients with type 2 diabetes. [RESEARCH DESIGN AND METHODS] A longitudinal cohort study was conducted using data from 105 type 2 diabetic patients in a clinical trial of a stress management intervention.... | null | 2.422 | 433 | Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine; Nursing | 2,000 |
10,976,980 | Use of and attitudes about alternative and complementary therapies among outpatients and physicians at a municipal hospital. | Journal of alternative and complementary medicine (New York, N.Y.) | J Altern Complement Med | 6 | 4 | 10.1089/10755530050120709 | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVES] To survey outpatients and physicians about their use of, knowledge of, and interest in alternative therapies. [DESIGN] Anonymous self-administered survey. [SETTINGS/LOCATION] Outpatient clinics at a major municipal medical center. [SUBJECTS] Outpatients visiting clinics and staff physicians. [INTERVENTIONS... | null | 0.445 | 0 | Complementary and Alternative Medicine | Medicine | 2,000 |
10,976,978 | Alternative/complementary medicine: wider usage than generally appreciated. | Journal of alternative and complementary medicine (New York, N.Y.) | J Altern Complement Med | 6 | 4 | 10.1089/10755530050120682 | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] To test the hypothesis that there is substantial use of a practitioner of alternative/complementary medicine by patients traditionally considered to be underserved. [DESIGN] Cross-sectional, self-administered survey study. [SETTINGS] Three university hospital-affiliated general ambulatory clinics serving pa... | null | 0.445 | 0 | Complementary and Alternative Medicine | Medicine | 2,000 |
10,976,729 | Quantification of hepatic and renal cortical echogenicity in clinically normal cats. | American journal of veterinary research | Am J Vet Res | 61 | 9 | 10.2460/ajvr.2000.61.1016 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To quantitatively determine echogenicity of the liver and renal cortex in clinically normal cats. [ANIMALS] 17 clinically normal adult cats. [PROCEDURE] 3 ultrasonographic images of the liver and the right kidney were digitized from video output from each cat. Without changing the ultrasound machine setting... | null | 0.796 | 105 | Medicine; Veterinary | Medicine; Veterinary | 2,000 |
10,976,550 | Slow chloroguanide metabolism in Tanzanians compared with white subjects and Asian subjects confirms a decreased CYP2C19 activity in relation to genotype. | Clinical pharmacology and therapeutics | Clin Pharmacol Ther | 68 | 2 | 10.1067/mcp.2000.108583 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] We have previously found decreased CYP2C19 activity in Tanzanians tested with mephenytoin and omeprazole in relation to genotype when compared with white and Asian subjects. [OBJECTIVE] We investigated the impact of CYP2C19 genotype and phenotype on chloroguanide (INN, proguanil) metabolism to its metaboli... | null | null | null | null | null | null |
10,976,415 | FISH analysis of six chromosomes in unfertilized human oocytes after polar body removal. | Journal of assisted reproduction and genetics | J Assist Reprod Genet | 17 | 5 | 10.1023/a:1009462400708 | eng | 2,000 | 5 | null | null | null | null | [PURPOSE] To develop an improved technique for estimating chromosomal abnormalities in human oocytes by fluorescence in situ hybridization (FISH) and to correlate the position of single chromatids with the chromosomal status of the oocytes. [METHODS] Oocytes that were at metaphase II about 17-20 hr after insemination o... | null | 0.707 | 101 | Medicine; Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology; Genetics; Genetics | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,974,292 | Immunohistochemical and immunogenetic analyses of ocular adnexal lymphoid proliferation. | Japanese journal of ophthalmology | Jpn J Ophthalmol | 44 | 4 | 10.1016/s0021-5155(00)00181-7 | eng | 2,000 | null | null | null | null | null | [PURPOSE] To compare polymerase chain reaction (PCR) results with histological, immunohistochemical, and clinical findings to understand the nature of ocular adnexal lymphoid proliferation. [METHODS] We examined 20 cases (21 specimens) of ocular adnexal lymphoid proliferation, using histological, immunohistochemical, a... | null | 0.445 | 70 | Medicine; Ophthalmology | Medicine | 2,000 |
10,973,846 | Myocardial strain by Doppler echocardiography. Validation of a new method to quantify regional myocardial function. | Circulation | Circulation | 102 | 10 | 10.1161/01.cir.102.10.1158 | eng | 2,000 | 9 | 5 | null | null | null | [BACKGROUND] Myocardial strain is a measure of regional deformation, and by definition, negative strain means shortening and positive strain, elongation. This study investigates whether myocardial strain can be measured by Doppler echocardiography as the time integral of regional velocity gradients, using sonomicrometr... | null | 5.669 | 691 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,000 |
10,973,545 | Role of nitric oxide in a temperature dependent regulation of systemic vascular resistance in cardiopulmonary bypass. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | Eur J Cardiothorac Surg | 18 | 3 | 10.1016/s1010-7940(00)00455-3 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVES] Nitric oxide is the most potent vasodilator among inflammation-mediated vasoactive substances. Tepid cardiopulmonary bypass has been known to maintain low vascular resistance and nitric oxide may also be involved. There has been no previous clinical study elucidating a role of nitric oxide in a temperature... | null | 0.86 | 158 | Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
10,972,700 | IF-LCM: laser capture microdissection of immunofluorescently defined cells for mRNA analysis rapid communication. | Kidney international | Kidney Int | 58 | 3 | 10.1046/j.1523-1755.2000.00295.x | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] The next phase of the molecular revolution will bring functional genomics down to the level of individual cells in a tissue. Laser capture microdissection (LCM) coupled with reverse transcription-polymerase chain reaction (RT-PCR) can measure gene expression in normal, cancerous, injured, or fibrotic tissu... | null | null | null | null | null | null |
10,972,630 | Use of direct thrombin inhibitors in acute coronary syndrome. | Clinical therapeutics | Clin Ther | 22 | 8 | 10.1016/S0149-2918(00)80065-X | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] This paper examines the rationale for using direct thrombin inhibitors in the management of acute coronary syndrome (ACS). [BACKGROUND] With traditional management of ACS using aspirin and unfractionated heparin (UH), refractory angina and new myocardial infarction (MI) continue to develop. Growing understa... | null | 0.768 | 153 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,000 |
10,972,217 | Laparoscopic live donor nephrectomy--is it safe? | Transplantation | Transplantation | 70 | 4 | 10.1097/00007890-200008270-00012 | eng | 2,000 | 8 | 27 | null | null | null | [BACKGROUND] Laparoscopic live donor nephrectomy (LDN) is a less invasive alternative to open nephrectomy (ODN) for living kidney donation. Concerns have been raised regarding the safety of LDN, the short and long term function of kidneys removed by LDN, and a potential higher incidence of urologic complications in LDN... | null | 2.115 | 224 | Transplantation | Medicine | 2,000 |
10,971,684 | Solubility, absorption, and anti-Helicobacter pylori activity of bismuth subnitrate and colloidal bismuth subcitrate: In vitro data Do not predict In vivo efficacy. | Helicobacter | Helicobacter | 5 | 3 | 10.1046/j.1523-5378.2000.00028.x | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVES] The aim of this study was to compare the dissolution, bioavailability, and anti-Helicobacter pylori activity of bismuth subnitrate and colloidal bismuth subcitrate. This could, first, provide insights into the mechanism of action of bismuth and, second, help to develop optimal therapeutic strategies. [METH... | null | 0.692 | 94 | Gastroenterology; Medicine; Infectious Diseases | Medicine | 2,000 |
10,971,056 | High body mass index, dry scaly leg skin and atopic conditions are highly associated with keratosis pilaris. | Dermatology (Basel, Switzerland) | Dermatology | 201 | 1 | 10.1159/000018425 | eng | 2,000 | null | null | null | null | null | [BACKGROUND] In a previous study we have found that young patients with insulin-dependent diabetes mellitus had a higher prevalence of keratosis pilaris (KP) than healthy controls, with a high correlation with body mass index (BMI) and ichthyosiform skin changes of the legs. [OBJECTIVES] To investigate whether BMI, dry... | null | 0.597 | 110 | Dermatology | Medicine | 2,000 |
10,969,431 | Success rates of formocresol pulpotomy and indirect pulp therapy in the treatment of deep dentinal caries in primary teeth. | Pediatric dentistry | Pediatr Dent | 22 | 4 | null | eng | 2,000 | null | null | null | null | null | [PURPOSE] This study was performed to retrospectively evaluate treatment of deep caries in primary molars with formocresol pulpotomy (FP) and indirect pulp therapy (IPT). [METHODS] 133 primary molars with deep caries approaching the pulp were treated with FP (N = 78) or IPT (N = 55) and followed 2-7 years. All IPTs rec... | null | null | null | null | null | null |
10,969,316 | Stereospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells. | Anesthesiology | Anesthesiology | 93 | 3 | 10.1097/00000542-200009000-00032 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Surprising clinical evidence suggests a block of sympathetic transmission by ketamine. The action of ketamine on nicotinic acetylcholine receptors (nAChRs) in human ganglions is unknown. Because ganglionic transmission depends on nAChRs, such information may help to clarify whether ketamine impairs ganglio... | null | null | null | null | null | null |
10,969,302 | Efficacy of preoxygenation with tidal volume breathing. Comparison of breathing systems. | Anesthesiology | Anesthesiology | 93 | 3 | 10.1097/00000542-200009000-00018 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Preoxygenation before tracheal intubation is intended to increase oxygen reserves and delay the onset of hypoxemia during apnea. Various systems are used for preoxygenation. Designed specifically for preoxygenation, the NasOral system uses a small nasal mask for inspiration and a mouthpiece for exhalation.... | null | null | null | null | null | null |
10,969,102 | Functional limitations and special health care needs of 10- to 14-year-old children weighing less than 750 grams at birth. | Pediatrics | Pediatrics | 106 | 3 | 10.1542/peds.106.3.554 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To examine the health status, functioning, and special health care needs of children 10 to 14 years old weighing 750 g at birth. [METHODS] We compared outcomes of a regional cohort of 59 children born from 1982 through 1986 weighing 750 g at birth (mean: 665 g; gestational age: 26 weeks) to matched groups o... | null | 2.062 | 409 | Pediatrics, Perinatology and Child Health | Medicine | 2,000 |
10,968,662 | Ethanol in human brain by magnetic resonance spectroscopy: correlation with blood and breath levels, relaxation, and magnetization transfer. | Alcoholism, clinical and experimental research | Alcohol Clin Exp Res | 24 | 8 | null | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Proton magnetic resonance spectroscopy (1H MRS) allows measurement of alcohol in the human brain after alcohol consumption. However, the quantity of alcohol that can be detected in the brain by 1H MRS pulse sequences has been controversial, with values ranging from about 24% to 94% of the temporally concor... | null | null | null | null | null | null |
10,967,584 | Peripheral arterial embolism. Report of hospitalized cases. | Arquivos brasileiros de cardiologia | Arq Bras Cardiol | 74 | 4 | 10.1590/s0066-782x2000000400003 | eng | 2,000 | 4 | null | null | null | null | [OBJECTIVE] We analyzed the frequency of peripheral embolisms, the underlying heart disease,triggering factors, the sites of the emboli, and evolution of the patients. [METHODS] We analyzed 29 cases of peripheral arterial embolism out of a total of 20,211 hospitalizations in a cardiology center in the city of São Paulo... | null | 0.133 | 66 | Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
10,967,266 | Bone mineral density in lung-transplant recipients before and after graft: prevention of lumbar spine post-transplantation-accelerated bone loss by pamidronate. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | J Heart Lung Transplant | 19 | 8 | 10.1016/s1053-2498(00)00132-7 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Lung-transplant recipients are at risk of osteoporosis. They may have low bone mass even before posttransplantation immunosuppressive therapy. We studied bone mineral density (BMD) before and after lung transplantation and compared the efficacy of antiresorptive therapies to calcium and vitamin D supplemen... | null | 1.162 | 162 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery; Transplantation | Medicine | 2,000 |
10,966,532 | Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin. | American heart journal | Am Heart J | 140 | 3 | 10.1067/mhj.2000.108514 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Between 10% and 30% of patients with symptoms similar to angina and sufficient to justify cardiac catheterization are found to have normal coronary angiograms. Treatment of patients with chest pain with no apparent cardiac cause is a major clinical problem. Our hypothesis was that sertraline would reduce t... | null | 1.441 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
10,966,287 | Development of a survey to measure parent satisfaction in a pediatric intensive care unit. | Critical care medicine | Crit Care Med | 28 | 8 | 10.1097/00003246-200008000-00055 | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] To use classic survey methodology to develop a specific survey tool that can assess parent satisfaction with medical care in a pediatric intensive care setting. [DESIGN] Application of survey design methodology to develop and analyze a parent satisfaction survey. [SETTING] A pediatric intensive care unit (P... | null | 0.691 | 315 | Critical Care and Intensive Care Medicine | Medicine | 2,000 |
10,966,187 | Near drowning: thin-section CT findings in six patients. | Journal of computer assisted tomography | J Comput Assist Tomogr | 24 | 4 | 10.1097/00004728-200007000-00009 | eng | 2,000 | null | null | null | null | null | [PURPOSE] The purpose of this study was to assess the thin-section CT findings of near drowning in six patients. [METHOD] Thin-section (1 mm collimation) CT scans of six patients who experienced near drowning were retrospectively analyzed. The CT scans were performed 0-5 days (median 1 day) after near drowning. [RESULT... | null | null | null | null | null | null |
10,965,232 | Strain-dependent association between lateralization and lipopolysaccharide- induced IL-1beta and IL-6 production in mice. | Neuroimmunomodulation | Neuroimmunomodulation | 8 | 2 | 10.1159/000026456 | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] The brain modulates the immune system in an asymmetrical way, as shown by the association between paw preference and immune response in the mouse. We predicted that the production of cytokines, which are one of the molecular pathways for brain-immune interactions, should be linked to lateralization in a str... | null | 0.736 | 76 | Endocrine and Autonomic Systems; Endocrinology; Immunology; Neurology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Neuroscience | 2,000 |
10,965,097 | Potential salvage therapy for accidental intrathecal vincristine administration: a preliminary experimental study. | Chemotherapy | Chemotherapy | 46 | 5 | 10.1159/000007305 | eng | 2,000 | null | null | null | null | null | [BACKGROUND] Accidental intrathecal vincristine (VCR) administration results in severe neurotoxicity, usually fatal in outcome. No specific therapy for initrathecal VCR toxicity has been reported so far. In our recent report, complete in vitro degradation of VCR by hypochlorous acid (HOCl) was demonstrated. [METHODS] I... | null | 0.406 | 63 | Medicine; Pharmacology; Pharmacology; Drug Discovery; Infectious Diseases; Oncology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,000 |
10,964,818 | Screening for amblyopia in preverbal children with photoscreening photographs: II. Sensitivity and specificity of the MTI photoscreener. | Ophthalmology | Ophthalmology | 107 | 9 | 10.1016/s0161-6420(00)00293-1 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To determine the sensitivity and specificity of vision screening using the Medical Technology and Innovations (MTI), Inc., PhotoScreener. [DESIGN] Cross-sectional study. PARTICIPANTS AND TESTING: Three hundred ninety-two children less than 4 years of age received a complete ophthalmologic examination and we... | null | 2.651 | 297 | Ophthalmology | Medicine | 2,000 |
10,964,300 | Temporal bone necrosis: diagnosis, classification, and management. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 123 | 3 | 10.1067/mhn.2000.107459 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] The goal of this study was to analyze temporal bone necrosis and classify its diagnosis and treatment according to extent of necrosis and cause. [METHODS AND MATERIAL] Twenty-six cases of temporal bone necrosis were retrospectively reviewed between 1988 and 1997 at the University of British Columbia. [RESUL... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,964,084 | Neurophysiological follow-up of motor cortical output in stroke patients. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | Clin Neurophysiol | 111 | 9 | 10.1016/s1388-2457(00)00373-4 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND AND PURPOSE] Transcranial magnetic stimulation (TMS) has been employed in following up a population of 20 stroke patients in a post-acute, apparently stabilized stage. Neurophysiological and clinical data were recorded in 5 different recording sessions, from the beginning of a neuro-rehabilitation treatment... | null | 0.606 | 230 | Neurology; Neurology; Physiology; Sensory Systems | Medicine; Neuroscience | 2,000 |
10,963,488 | Are coagulation studies necessary before percutaneous nephrostomy? | Techniques in urology | Tech Urol | 6 | 3 | null | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] Performance of coagulation studies for patients undergoing percutaneous nephrostomy (PCN) has been advocated by some investigators. We performed a retrospective study to assess this practice. [MATERIALS AND METHODS] The medical records of 180 patients subjected to PCN for various reasons between October 1991 ... | null | null | null | null | null | null |
10,962,783 | Social variation in reasons for contacting general practice out-of-hours: implications for daytime service provision? | The British journal of general practice : the journal of the Royal College of General Practitioners | Br J Gen Pract | 50 | 455 | null | eng | 2,000 | 6 | null | null | null | null | [BACKGROUND] Contact with general practice out-of-hours services increases with socioeconomic deprivation. The reasons for this association are unclear but may include variations in access to daytime services or differences in morbidity. [AIM] To identify the reasons for contact with the Glasgow Emergency Medical Servi... | null | 1.089 | 125 | Family Practice; Medicine | Medicine | 2,000 |
10,962,623 | Arrowroot as a treatment for diarrhoea in irritable bowel syndrome patients: a pilot study. | Arquivos de gastroenterologia | Arq Gastroenterol | 37 | 1 | 10.1590/s0004-28032000000100005 | eng | 2,000 | null | null | null | null | null | [OBJECTIVES] Arrowroot is an old-fashioned remedy for diarrhoea, but no clinical studies have been done to evaluate its effectiveness. The aim of this pilot study was to assess its efficacy as a treatment for diarrhoea in 11 patients, all of whom had irritable bowel syndrome with diarrhoea as a feature. [METHODS] The p... | null | 0.143 | 40 | Gastroenterology | Medicine | 2,000 |
10,962,304 | Noninvasive urodynamic evaluation of bladder outlet obstruction using Doppler ultrasonography. | Urology | Urology | 56 | 3 | 10.1016/s0090-4295(00)00684-1 | eng | 2,000 | 9 | 1 | null | null | null | [OBJECTIVES] Previously we had developed a new method of noninvasive urodynamics using color Doppler ultrasound. Using this technique, we attempted to identify parameters that would diagnose bladder outlet obstruction (BOO). [METHODS] Twenty-two men who underwent pressure-flow urodynamic studies were included. Color sc... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,962,041 | Clinical application of three-dimensional ultrasound in fetal brain assessment. | Croatian medical journal | Croat Med J | 41 | 3 | null | eng | 2,000 | 9 | null | null | null | null | [AIM] To clarify the usefulness of three-dimensional (3D) ultrasound in the assessment of the fetal head and brain, according to 3D ultrasound surface reconstruction, multiplanar image analysis, three-dimensional angiography, and volume calculation. [METHODS] We examined 326 normal fetuses between 10 and 40 weeks of ge... | null | null | null | null | null | null |
10,960,750 | Splints and stress transmission to teeth: an in vitro experiment. | Journal of dentistry | J Dent | 28 | 7 | 10.1016/s0300-5712(00)00026-9 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To determine the influence of hard and soft splints with two thicknesses on the stress transmission to the tooth supporting the splint and the opposite tooth. [METHODS] Continuous vertical forces up to 500N were applied to two opposite first molar phantom teeth using a universal loading machine. Deformation... | null | 0.975 | 146 | Dentistry | Dentistry | 2,000 |
10,960,523 | Infectious disease markers in young blood donors. Retrovirus Epidemiology Donor Study. | Transfusion | Transfusion | 40 | 8 | 10.1046/j.1537-2995.2000.40080954.x | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] To evaluate whether the active recruitment of young donors of high school and college age could affect the safety of the blood supply, prevalence and incidence rates of infectious disease markers among donors aged 17 to 18 and 19 to 22 were compared to those in donors 23 years of age and older. [STUDY DESI... | null | 1.209 | 153 | Hematology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,000 |
10,959,837 | Forkhead transcription factors, Fkh1p and Fkh2p, collaborate with Mcm1p to control transcription required for M-phase. | Current biology : CB | Curr Biol | 10 | 15 | 10.1016/s0960-9822(00)00618-7 | eng | null | null | null | null | null | null | [BACKGROUND] The 'CLB2 cluster' in Saccharomyces cerevisiae consists of approximately 33 genes whose transcription peaks in late G2/early M phase of the cell cycle. Many of these genes are required for execution of the mitotic program and then for cytokinesis. The transcription factor SFF (SWI5 factor) is thought to re... | null | null | null | null | null | null |
10,959,836 | A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. | Current biology : CB | Curr Biol | 10 | 15 | 10.1016/s0960-9822(00)00610-2 | eng | null | null | null | null | null | null | [BACKGROUND] The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors into nuclear foci. Recently it has been reported that a member of the histone H2A family, H2AX, becomes extensively phosphorylated within 1-3 minutes of DNA damage and forms foci at break site... | null | null | null | null | null | null |
10,956,297 | Clinical and angiographic outcome in patients with in-stent restenosis and repeat target lesion revascularisation in small coronary arteries. | Heart (British Cardiac Society) | Heart | 84 | 3 | 10.1136/heart.84.3.307 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To evaluate the clinical and angiographic outcome in patients with in-stent restenosis in small coronary arteries and repeat target lesion revascularisation. [DESIGN] Patients with in-stent restenosis in coronary arteries or = 2.85 mm were eligible for the study and underwent target lesion revascularisatio... | null | 0.675 | 214 | Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
10,955,852 | Morphine antinociception is enhanced in mdr1a gene-deficient mice. | Pharmaceutical research | Pharm Res | 17 | 6 | 10.1023/a:1007546719287 | eng | 2,000 | 6 | null | null | null | null | [PURPOSE] Previous studies have suggested that P-glycoprotein (P-gp) modulates opioid antinociception for selected mu-and delta-agonists. This study was undertaken to assess morphine antinociception in mice lacking the mdr1a gene for expression of P-gp in the CNS. [METHODS] Morphine (n = 4-5/group) was administered as ... | null | 1.067 | 235 | Biotechnology; Organic Chemistry; Pharmaceutical Science; Pharmacology; Pharmacology; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,000 |
10,955,343 | The assessment of functional impairment in fibromyalgia (FM): Rasch analyses of 5 functional scales and the development of the FM Health Assessment Questionnaire. | The Journal of rheumatology | J Rheumatol | 27 | 8 | null | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] Functional assessment by self-report questionnaire plays an important role in most rheumatic conditions, but psychometric properties of questionnaires have not been studied in fibromyalgia (FM), particularly by Rasch analysis, which allows for examining adequacy of the questionnaire scale. To assess current... | null | 1.162 | 201 | Immunology and Allergy; Rheumatology; Immunology | Immunology and Microbiology; Medicine | 2,000 |
10,955,330 | Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjögren's syndrome-like autoimmune exocrinopathy. | The Journal of rheumatology | J Rheumatol | 27 | 8 | null | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] NOD mice exhibit at least 2 overlapping autoimmune diseases: autoimmune endocrinopathy (Type I, insulin dependent diabetes) and autoimmune exocrinopathy (Sjogren's syndrome, SS). To date, 18 chromosomal regions have been identified that contribute to development of diabetes in NOD mice; however, genetic map... | null | 1.162 | 201 | Immunology and Allergy; Rheumatology; Immunology | Immunology and Microbiology; Medicine | 2,000 |
10,954,662 | Low-dose adjunctive spironolactone in the treatment of acne in women: a retrospective analysis of 85 consecutively treated patients. | Journal of the American Academy of Dermatology | J Am Acad Dermatol | 43 | 3 | 10.1067/mjd.2000.105557 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Despite advances in acne therapy in recent years, treatment failures are common, especially in adult women. Spironolactone, an established androgen receptor blocker, is successful in treating adult women with acne, but side effects are common at the doses reported in published studies to date. [OBJECTIVE] ... | null | 1.201 | 256 | Dermatology | Medicine | 2,000 |
10,954,639 | Reliability of magnetic resonance imaging in detecting posterior ligament complex injury in thoracolumbar spinal fractures. | Spine | Spine (Phila Pa 1976) | 25 | 16 | 10.1097/00007632-200008150-00012 | eng | 2,000 | 8 | 15 | null | null | null | [STUDY DESIGN] Prospective study of 34 patients with thoracolumbar spinal fractures. [OBJECTIVES] To assess the reliability of magnetic resonance imaging (MRI) for posterior ligament complex injury in thoracolumbar spinal fractures. [SUMMARY OF BACKGROUND DATA] Some researchers have studied posterior ligament complex i... | null | 1.319 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,000 |
10,954,387 | Mental health disorders in children and young people: scope, cause and prevention. | The Australian and New Zealand journal of psychiatry | Aust N Z J Psychiatry | 34 | 4 | 10.1080/j.1440-1614.2000.00703.x | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] To review the scope and characteristics of mental health disorders in children and young people in Australia; detail some emerging concepts of the causal pathways of mental health disorders in children and young people; and discuss aspects of the prevention of mental health disorders and the promotion of me... | null | 0.548 | 140 | Medicine; Psychiatry and Mental Health | Medicine | 2,000 |
10,954,286 | The pterygopalatine fossa: postoperative MR imaging appearance. | AJNR. American journal of neuroradiology | AJNR Am J Neuroradiol | 21 | 7 | null | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND AND PURPOSE] The pterygopalatine fossa (PPF) is an important anatomic location of the deep portion of the face. It is essential to review this area on both pre- and posttreatment studies of head and neck malignancies to assess local extent of disease or recurrence and perineural tumor spread. The purpose of... | null | null | null | null | null | null |
10,954,102 | Current trends in the management of adamantinoma of long bones. An international study. | The Journal of bone and joint surgery. American volume | J Bone Joint Surg Am | 82 | 8 | 10.2106/00004623-200008000-00009 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Adamantinoma of long bones is a rare tumor. Published reviews of the orthopaedic management of adamantinoma have involved limited follow-up of small numbers of patients. The oncological aggressiveness of this tumor is unknown. Limb salvage is currently the treatment of choice for most adamantinomas. The pu... | null | null | null | null | null | null |
10,954,007 | Pilot study of combined blockade of the renin-angiotensin system in essential hypertensive patients. | Journal of hypertension | J Hypertens | 18 | 8 | 10.1097/00004872-200018080-00020 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Additive hemodynamic effects of combined blockade of the renin-angiotensin system by an angiotensin I converting enzyme inhibitor and an angiotensin II antagonist have been observed in sodium-depleted normotensive volunteers and in patients with congestive heart failure. [OBJECTIVE] To investigate whether ... | null | 1.333 | 198 | Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,953,853 | Applying some UK Prospective Diabetes Study results to Switzerland: the cost-effectiveness of intensive glycaemic control with metformin versus conventional control in overweight patients with type-2 diabetes. | Schweizerische medizinische Wochenschrift | Schweiz Med Wochenschr | 130 | 27-28 | null | eng | 2,000 | 7 | 11 | null | null | null | [OBJECTIVE] The results of the metformin substudy of the United Kingdom Prospective Diabetes Study (UKPDS) were applied through modelling techniques to the Swiss setting, allowing a cost-effectiveness analysis of the management of overweight type-2 diabetes patients with either conventional glycaemic control or intensi... | null | null | null | null | null | null |
10,953,708 | Continuing education needs assessment for on-farm food safety services. | Journal of the American Veterinary Medical Association | J Am Vet Med Assoc | 217 | 4 | 10.2460/javma.2000.217.479 | eng | 2,000 | 8 | 15 | null | null | null | [OBJECTIVE] To identify the perceived market or client demand for dairy on-farm food safety services by veterinarians, the need for a food safety continuing education program, and the educational issues that might be addressed in an on-farm food safety curriculum. [DESIGN] Survey. [STUDY POPULATION] Consulting dairy ve... | null | 0.731 | 137 | Veterinary | Veterinary | 2,000 |
10,953,326 | Reduction in p53 gene dosage diminishes differentiation capacity of osteoblasts. | Anticancer research | Anticancer Res | 20 | 4 | null | eng | 2,000 | null | null | null | null | null | [BACKGROUND] Loss of p53 function is seen in a large number of human tumors including osteosarcoma, and in previous studies we have demonstrated a close relationship between wild type p53 and osteoblasts differentiation. In the present study we attempted to understand the relationship of bone growth and differentiation... | null | null | null | null | null | null |
10,953,168 | Solid-state 13 C and 31 P NMR analysis of urinary stones. | The Journal of urology | J Urol | 164 | 3 Pt 1 | 10.1097/00005392-200009010-00062 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] We investigated the applicability of solid-state nuclear magnetic resonance (NMR) spectroscopy to obtain information about the structure and composition of renal calculi. [MATERIALS AND METHODS] Various types urinary and bladder stones as well as a variety of presumed constituents were investigated using 13C ... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
10,953,156 | Long-term efficacy of simple behavioral therapy for daytime wetting in children. | The Journal of urology | J Urol | 164 | 3 Pt 1 | 10.1097/00005392-200009010-00048 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] Behavioral therapy has proved benefit for children with daytime wetting but most studies have used biofeedback techniques and provide no long-term assessment of results. We previously reported similar results using simple behavioral therapy without biofeedback. We report the long-term efficacy of behavioral t... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
10,952,245 | Epidermal growth factor is decreased in liver of rats with biliary cirrhosis but does not act as paracrine growth factor immediately after hepatectomy. | Journal of hepatology | J Hepatol | 33 | 2 | 10.1016/s0168-8278(00)80368-2 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND/AIMS] Epidermal growth factor, a potent mitogen for hepatocytes and cholangiocytes, is thought to act as an immediate-early gene after partial hepatectomy. Since regeneration is impaired in cirrhosis, we explored the expression of epidermal growth factor in cirrhotic rat liver immediately after partial hepa... | null | 1.219 | 319 | Hepatology | Medicine | 2,000 |
10,952,234 | Volume-sensitive purinergic signaling in human hepatocytes. | Journal of hepatology | J Hepatol | 33 | 2 | 10.1016/s0168-8278(00)80357-8 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND/AIMS] Purinergic signaling potentially contributes to many liver functions. Therefore, the purpose of these studies was to characterize adenosine 5'-triphosphate (ATP) release from human hepatocytes, and to determine the role of extracellular ATP in the autocrine regulation of Cl- permeability and cell volu... | null | 1.219 | 319 | Hepatology | Medicine | 2,000 |
10,951,988 | Use of a nonionic detergent (Triton WR 1339) in healthy cats to assess hepatic secretion of triglyceride. | American journal of veterinary research | Am J Vet Res | 61 | 8 | 10.2460/ajvr.2000.61.941 | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] To determine whether a nonionic detergent (Triton WR 1339) can be used in cats to assess hepatic secretion of triglyceride. [ANIMALS] 28 healthy cats. [PROCEDURE] Triton WR 1339 was administered IV according to the following schedule: 5, 50, 150, and 250 mg/kg of body weight. Control cats did not receive an... | null | 0.796 | 105 | Medicine; Veterinary | Medicine; Veterinary | 2,000 |
10,951,546 | The relationship between body mass index and waist circumference: implications for estimates of the population prevalence of overweight. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity | Int J Obes Relat Metab Disord | 24 | 8 | 10.1038/sj.ijo.0801359 | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] Body mass index (BMI) based on self-reported height and weight is a systematically biased, but acceptable measure of adiposity and is commonly used in population surveys. Recent studies indicate that abdominal obesity is more strongly associated with obesity-related health problems than is adiposity measure... | null | null | null | null | null | null |
10,951,544 | Functional and histological characteristics of skeletal muscle and the effects of leptin in the genetically obese (ob/ob) mouse. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity | Int J Obes Relat Metab Disord | 24 | 8 | 10.1038/sj.ijo.0801357 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Skeletal muscle mass in genetically obese (ob/ob) mice displays a reduced mass compared with their normal lean counterpart mice. However, the functional capacity of the available skeletal muscle mass in these animals has not yet been determined. [OBJECTIVE] To investigate the properties of skeletal muscle ... | null | null | null | null | null | null |
10,951,492 | Antibacterial activity of human prostasomes. | The Prostate | Prostate | 44 | 4 | 10.1002/1097-0045(20000901)44:4279::aid-pros43.0.co;2-2 | eng | 2,000 | 9 | 1 | null | null | null | [BACKGROUND] Prostasomes are prostate-derived organelles in semen exhibiting pluripotent properties. The present study deals with their possible antibacterial effects. [METHODS] Antibacterial activity was assessed by growth inhibition of bacteria in an incubation medium containing prostasomes, after which the incubate ... | null | 1.503 | 138 | Oncology; Urology | Medicine | 2,000 |
10,951,299 | Treatment of nasolacrimal duct obstruction in children with trisomy 21. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus | J AAPOS | 4 | 4 | 10.1067/mpa.2000.105272 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Nasolacrimal duct (NLD) obstruction and tear film abnormalities occur frequently in children with trisomy 21. This study describes the outcomes of treatment for NLD obstruction in this population. [METHODS] The records of 15 children with trisomy 21 treated for NLD obstruction were reviewed. Eight patients... | null | 0.521 | 82 | Pediatrics, Perinatology and Child Health; Ophthalmology | Medicine | 2,000 |
10,951,147 | Randomized double-blind study of cyclosporin in chronic 'idiopathic' urticaria. | The British journal of dermatology | Br J Dermatol | 143 | 2 | 10.1046/j.1365-2133.2000.03664.x | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Histamine-releasing activity (HRA) is detectable in up to 50% of patients with chronic ordinary urticaria. [OBJECTIVES] To determine the effect of cyclosporin on clinical features and HRA in patients with chronic urticaria. [METHODS] Thirty patients with severe unremitting disease, responding poorly to ant... | null | 1.037 | 214 | Dermatology; Medicine | Medicine | 2,000 |
10,950,900 | Recent trends in physician diagnosed COPD in women and men in the UK. | Thorax | Thorax | 55 | 9 | 10.1136/thorax.55.9.789 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Recent trends in physician diagnosed chronic obstructive pulmonary disease (COPD) in the UK were estimated, with a particular focus on women. [METHODS] A retrospective cohort of British patients with COPD was constructed from the General Practice Research Database (GPRD), a large automated database of UK g... | null | 0.995 | 259 | Pulmonary and Respiratory Medicine | Medicine | 2,000 |
10,950,898 | Salmeterol in paediatric asthma. | Thorax | Thorax | 55 | 9 | 10.1136/thorax.55.9.780 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] The addition of long acting inhaled beta(2) agonists is recommended at step 3 of the British guidelines on asthma management but a recent study suggested no additional benefit in children with asthma. [METHODS] The aim of this study was to compare, in a double blind, three way, crossover study, the effects... | null | 0.995 | 259 | Pulmonary and Respiratory Medicine | Medicine | 2,000 |
10,950,052 | Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: a hemodynamic evaluation. | The American journal of gastroenterology | Am J Gastroenterol | 95 | 8 | 10.1111/j.1572-0241.2000.02266.x | eng | 2,000 | 8 | null | null | null | null | [OBJECTIVE] In the present study, we attempted to complete the hemodynamic assessment of propranolol response in cirrhotics with esophageal varices at high risk of bleeding, in one sitting, so as to identify nonresponders at the earliest. Some noninvasive indicators of this response were also evaluated. [METHODS] Hepat... | null | 1.058 | 296 | Gastroenterology; Hepatology | Medicine | 2,000 |
10,949,723 | Anti-cardiolipin antibody from a patient with antiphospholipid syndrome (APS) recognizes only an epitope expressed by cardiolipin/beta 2-glycoprotein-I (beta 2GPI) complex and induces APS. | Clinical and experimental rheumatology | Clin Exp Rheumatol | 18 | 4 | null | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] As the antiphospholipid syndrome (APS) is characterized by antibodies which bind negatively charged phospholipids either directly or mainly through different target epitopes located on the beta-2-glycoprotein-I (beta 2GPI) molecule, the aim of this study is to describe an additional target epitope for anti-... | null | 0.56 | 112 | Immunology and Allergy; Rheumatology; Immunology | Immunology and Microbiology; Medicine | 2,000 |
10,949,099 | Tryptophan levels, excessive exercise, and nutritional status in anorexia nervosa. | Psychosomatic medicine | Psychosom Med | 62 | 4 | 10.1097/00006842-200007000-00012 | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] It has been hypothesized that reduced dietary availability of tryptophan may be the cause of impaired serotonin activity in underweight anorexics. The study reported here evaluated the relationship between tryptophan availability in the blood and nutritional status in anorexia nervosa. [METHODS] The total a... | null | 1.882 | 214 | Applied Psychology; Developmental and Educational Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,000 |
10,949,000 | Overuse injuries in the elite rock climber. | Medicine and science in sports and exercise | Med Sci Sports Exerc | 32 | 8 | 10.1097/00005768-200008000-00002 | eng | 2,000 | 8 | null | null | null | null | [UNLABELLED] Closed rupture of the flexor tendon sheath has been known to occur in the elite rock climbing population. However, only one study has investigated the prevalence of this entity. [PURPOSE] To examine an elite climbing group in this country for the prevalence of pulley rupture and report on other commonly oc... | null | 1.292 | 271 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,000 |
10,948,294 | Bile duct injury during laparoscopic cholecystectomy: myth or reality of the learning curve? | Surgical endoscopy | Surg Endosc | 14 | 7 | 10.1007/s004640000103 | eng | 2,000 | 7 | null | null | null | null | [BACKGROUND] Bile duct injury (BDI) is a severe complication of laparoscopic cholecystectomy (LC) that is probably related to the effects of the learning curve. The aim of this prospective, institutional, and longitudinal study is to compare the incidence of BDI during LC in relation to the progressive experience of su... | null | 1.428 | 178 | Surgery | Medicine | 2,000 |
11,071,583 | Pyarthrosis in patients with rheumatoid arthritis: a detailed analysis of 10 cases and literature review. | Seminars in arthritis and rheumatism | Semin Arthritis Rheum | 30 | 2 | 10.1053/sarh.2000.9205 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] 1) To analyze the clinical features and outcome of patients with rheumatoid arthritis and pyarthrosis seen in a rheumatology department during a 9-year period; 2) To review the available literature about this association in the last decade. [METHODS] From the database of our department, we collected all ho... | null | 1.038 | 139 | Anesthesiology and Pain Medicine; Rheumatology | Medicine | 2,000 |
11,071,108 | Visual evoked potentials in cerebral white matter hyperintensity on MRI. | Acta neurologica Scandinavica | Acta Neurol Scand | 102 | 4 | 10.1034/j.1600-0404.2000.102004230.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] To investigate the correlation of the cerebral white matter hyperintensities (WMH) on MRI, and latency and amplitude of visual evoked potentials (VEPs) in elderly subjects. [PATIENTS AND METHODS] Pattern VEP (PVEP) and flash VEP (FVEP) were recorded in 25 patients with WMH consisting of 12 patients with fr... | null | 0.711 | 114 | Medicine; Neurology; Neurology | Medicine; Neuroscience | 2,000 |
11,069,725 | Visually-guided irrigation in patients with early knee osteoarthritis: a multicenter randomized, controlled trial. | Osteoarthritis and cartilage | Osteoarthritis Cartilage | 8 | 6 | 10.1053/joca.1999.0316 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] To determine if visually-guided arthroscopic irrigation is an effective therapeutic intervention in patients with early knee osteoarthritis. [DESIGN] Ninety patients with knee osteoarthritis were randomized in a double-blind fashion to receive either arthroscopic irrigation with 3000 ml of saline (treatment... | null | 1.025 | 197 | Biomedical Engineering; Orthopedics and Sports Medicine; Rheumatology | Engineering; Medicine | 2,000 |
11,069,400 | Preoperative simulation of partial nephrectomy with three-dimensional computed tomography. | BJU international | BJU Int | 86 | 7 | 10.1046/j.1464-410x.2000.00898.x | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] To evaluate prospectively the accuracy of computer-aided three-dimensional (3D) volume-rendered computed tomography (CT) in determining the appropriate anatomical limits (tumour size, tumour location, multifocality and vascular supply) and as a potential tool in the preoperative simulation of nephron-sparin... | null | 0.469 | 174 | Urology | Medicine | 2,000 |
11,069,388 | Allogeneic whole-tumour cell vaccination in the rat model of prostate cancer. | BJU international | BJU Int | 86 | 6 | 10.1046/j.1464-410x.2000.00887.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To investigate cancer immunotherapy using whole allogeneic (differing tissue-type) tumour cells as vaccines in the rat prostate cancer model. Materials and methods Two rat models of prostate cancer were used; MAT-LyLu tumours which grow in Copenhagen rats and PAIII tumours which grow in Lobund-Wistar rats, ... | null | 0.469 | 174 | Urology | Medicine | 2,000 |
11,068,311 | Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia. | Urology | Urology | 56 | 5 | 10.1016/s0090-4295(00)00776-7 | eng | 2,000 | 11 | 1 | null | null | null | [OBJECTIVES] To validate with an independent study that simple atrophy/postatrophic hyperplastic lesions (proliferative inflammatory atrophy [PIA]) often merge directly with high-grade prostatic intraepithelial neoplasia (PIN). [METHODS] Using radical prostatectomies (n =14), all high-grade PIN and adenocarcinoma lesio... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
11,067,374 | Clinical and cost implications of new technologies for cervical cancer screening: the impact of test sensitivity. | The American journal of managed care | Am J Manag Care | 6 | 7 | null | eng | 2,000 | 7 | null | null | null | null | [OBJECTIVE] To compare the available techniques for cervical cancer screening, including several new technologies, using actual program utilization patterns. [STUDY DESIGN] Longitudinal cohort model. [PATIENTS AND METHODS] The model followed a cohort of 100,000 women who underwent screening from age 20 through 65 years... | null | 0.304 | 110 | Health Policy; Medicine | Medicine | 2,000 |
11,067,373 | Comparing the medical expenses of children with Medicaid and commercial insurance in an HMO. | The American journal of managed care | Am J Manag Care | 6 | 7 | null | eng | 2,000 | 7 | null | null | null | null | [BACKGROUND] In recent years, growing numbers of children with Medicaid have been enrolled in managed care plans nationwide. Yet, large, commercial managed care plans are increasingly discontinuing their participation in Medicaid because of low Medicaid payment rates. [OBJECTIVE] To compare the healthcare utilization a... | null | 0.304 | 110 | Health Policy; Medicine | Medicine | 2,000 |
11,066,050 | Implication of telomerase activity and alternations of telomere length in the histologic characteristics of intracranial meningiomas. | Cancer | Cancer | 89 | 10 | 10.1002/1097-0142(20001115)89:10<2092::aid-cncr9>3.0.co;2-n | eng | 2,000 | 11 | 15 | null | null | null | [BACKGROUND] Telomerase activity and telomere length have been shown to be involved in the control of cell proliferation and regulation of cell senescence. The expression of telomerase activity may endow cells with the capacity of unlimited proliferation and immortality. The authors examined the telomerase activity and... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,066,042 | Sporadic colorectal adenocarcinomas with high-frequency microsatellite instability. | Cancer | Cancer | 89 | 10 | null | eng | 2,000 | 11 | 15 | null | null | null | [BACKGROUND] Widespread microsatellite instability (MSI) occurs in nearly 15% of sporadic colorectal cancers. Large bowel carcinomas with high-frequency MSI (MSI-H) (instability at > or = 30% of microsatellite loci) are believed to display distinctive pathologic features and to behave less aggressively than microsatell... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,064,394 | Bone metastases from squamous cell carcinoma of the head and neck. | Journal of surgical oncology | J Surg Oncol | 75 | 2 | 10.1002/1096-9098(200010)75:2<136::aid-jso11>3.0.co;2-d | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND AND OBJECTIVES] Carcinoma of the head and neck is an uncommon primary source of bone metastases. The increasing duration of survival of these patients, however, increases the probability of late bone involvement. The objective was to identify the frequency, clinical presentation, and clinical course of meta... | null | 0.731 | 136 | Medicine; Surgery; Oncology | Medicine | 2,000 |
11,064,360 | Increasing levels of hypoxia in prostate carcinoma correlate significantly with increasing clinical stage and patient age: an Eppendorf pO(2) study. | Cancer | Cancer | 89 | 9 | 10.1002/1097-0142(20001101)89:9<2018::aid-cncr19>3.3.co;2-p | eng | 2,000 | 11 | 1 | null | null | null | [BACKGROUND] The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. [METHODS] Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,063,657 | Surgical stapling technique for radical hysterectomy: survival, recurrence, and late complications. | Gynecologic oncology | Gynecol Oncol | 79 | 2 | 10.1006/gyno.2000.5948 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] The aim of this study was to conduct a long-term follow-up of the surgical stapling technique of radical hysterectomy to determine survival, recurrence, and late complications. [METHODS] One hundred consecutive eligible patients treated with the surgical stapling technique of radical hysterectomy were prosp... | null | 0.979 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,000 |
11,063,339 | Expression of angiotensin II type I receptor on erythroid progenitors of patients with post transplant erythrocytosis. | Transplantation | Transplantation | 70 | 8 | 10.1097/00007890-200010270-00011 | eng | 2,000 | 10 | 27 | null | null | null | [BACKGROUND] The pathogenesis of posttransplant erythrocytosis (PTE) has been elusive. Angiotensin converting enzyme inhibitors (ACEI) are efficacious in lowering the hematocrit of patients with PTE and angiotensin II (AII) type I receptors (AT1R) were recently detected on red blood cell precursors, burst-forming unit-... | null | 2.115 | 224 | Transplantation | Medicine | 2,000 |
11,063,336 | Long-term oral ganciclovir prophylaxis for prevention of cytomegalovirus infection and disease in cytomegalovirus high-risk renal transplant recipients. | Transplantation | Transplantation | 70 | 8 | 10.1097/00007890-200010270-00008 | eng | 2,000 | 10 | 27 | null | null | null | [BACKGROUND] Although specific therapy is available with ganciclovir, cytomegalovirus (CMV) disease remains a major problem after renal transplantation especially in CMV seronegative recipients of organs of seropositive donors (D+R-). [METHODS] In an open-labeled prospective controlled trial we evaluated the effect of ... | null | 2.115 | 224 | Transplantation | Medicine | 2,000 |
11,063,109 | Soleus neurotomy for treatment of the spastic equinus foot. Groupe d'Evaluation et de Traitement de la Spasticité et de la Dystonie. | Neurosurgery | Neurosurgery | 47 | 5 | 10.1097/00006123-200011000-00027 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] This prospective, nonrandomized, noncontrolled study was performed to evaluate the results of a new type of neurotomy, namely the soleus neurotomy, for treatment of the spastic equinus foot. [METHODS] Between May 1996 and March 1998, 46 patients were treated for a spastic equinus foot. Clinical status, spas... | null | 1.741 | 229 | Neurology; Surgery | Medicine | 2,000 |
11,062,853 | Very low sperm count affects the result of intracytoplasmic sperm injection. | Journal of assisted reproduction and genetics | J Assist Reprod Genet | 17 | 8 | 10.1023/a:1009413201849 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] The aim was to examine the influence of extremely low sperm count on intracytoplasmic sperm injection (ICSI) outcome. [METHODS] Over 1000 consecutive unselected ICSI cycles were divided into four groups according to sperm concentration of their patients: A, cryptozoospermia, 107 patients; B, sperm concentrati... | null | 0.707 | 101 | Medicine; Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology; Genetics; Genetics | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,062,790 | Potential roles for quantitative ultrasound in the management of osteoporosis. | The Medical journal of Australia | Med J Aust | 173 | 7 | 10.5694/j.1326-5377.2000.tb125686.x | eng | 2,000 | 10 | 2 | null | null | null | [OBJECTIVE] To assess the validity of four models for the role of quantitative ultrasound (QUS) in the management of osteoporosis. [DESIGN] Cross-sectional survey and review of literature. [SETTINGS] Nuclear medicine departments of three teaching hospitals in Sydney. [SUBJECTS] 1000 women aged 22 to 88 years (mean, 59 ... | null | 0.617 | 156 | Medicine | Medicine | 2,000 |
11,062,382 | Comparative study of the clinical efficacy of two dosing regimens of flutamide. | Molecular urology | Mol Urol | 4 | 3 | null | eng | 2,000 | null | null | null | null | null | [PURPOSE] We performed a randomized trial to compare the efficacy and toxicity of a new dose of flutamide (500 mg QD) with the currently recommended dose (250 mg q8h) in the treatment of advanced prostate cancer. The primary endpoints were percent of patients having normalization of prostate specific antigen (PSA), tim... | null | null | null | null | null | null |
11,062,294 | Heritability of intracerebral hemorrhagic lesions and cerebral aneurysms in the rat. | Stroke | Stroke | 31 | 11 | 10.1161/01.str.31.11.2678 | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND AND PURPOSE] Under certain conditions, the Brown Norway (BN) rat is susceptible to intracerebral hemorrhagic vascular (ICV) lesions within the cerebral cortex, whereas the Long-Evans (LE) rat is prone to develop aneurysms in the circle of Willis. The incidence of these 2 pathological phenotypes was studied ... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
11,062,231 | Impact of a computer-based patient record system on data collection, knowledge organization, and reasoning. | Journal of the American Medical Informatics Association : JAMIA | J Am Med Inform Assoc | 7 | 6 | 10.1136/jamia.2000.0070569 | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] To assess the effects of a computer-based patient record system on human cognition. Computer-based patient record systems can be considered "cognitive artifacts," which shape the way in which health care workers obtain, organize, and reason with knowledge. [DESIGN] Study 1 compared physicians' organization ... | null | 0.989 | 184 | Health Informatics | Medicine | 2,000 |
11,061,942 | Identification by quantitative chromatin pattern analysis of patients at risk for recurrence of superficial transitional bladder carcinoma. | The Journal of urology | J Urol | 164 | 6 | 10.1097/00005392-200012000-00078 | eng | 2,000 | 12 | null | null | null | null | [PURPOSE] Based on the actual clinical outcomes of 132 fully documented patients with superficial transitional cell carcinoma of the bladder, we characterize the risk of recurrence and/or progression by computer assisted image microscopy applied to Feulgen stained nuclei. [MATERIALS AND METHODS] Each tumor was characte... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
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