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11,061,925 | Intraoperative pharmacological erection as an aid to pediatric hypospadias repair. | The Journal of urology | J Urol | 164 | 6 | null | eng | 2,000 | 12 | null | null | null | null | [PURPOSE] The intraoperative evaluation of erection is a major advance in hypospadias surgery. We determined the advantages of erections induced pharmacologically over those induced by intracorporeal saline injection for evaluating chordee during hypospadias surgery. [MATERIALS AND METHODS] During the repair of hypospa... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
11,061,058 | Assessment of left ventricular systolic function in patients with idiopathic mitral valve prolapse using dobutamine stress echocardiography. | Clinical cardiology | Clin Cardiol | 23 | 10 | 10.1002/clc.4960231017 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] Some previous studies performed with radionuclide ventriculography and thallium scintigraphy reported that patients with idiopathic mitral valve prolapse (MVP) had some degree of left ventricular (LV) systolic dysfunction and that this dysfunction was more commonly found in symptomatic patients. [HYPOTHESI... | null | 0.648 | 89 | Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
11,061,056 | Relationship between mean right atrial pressure and Doppler parameters in patients with right ventricular infarction. | Clinical cardiology | Clin Cardiol | 23 | 10 | 10.1002/clc.4960231015 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] The incidence of an inferior left ventricular infarction involving the right ventricle is very high, ranging from 14 to 84%. Isolated right ventricular infarction accounts for < 3% of all cases of infarction. [HYPOTHESIS] The aim of the present study was to assess the relationship between Doppler parameter... | null | 0.648 | 89 | Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
11,061,053 | Improved survival after acute myocardial infarction in patients with advanced Killip class. | Clinical cardiology | Clin Cardiol | 23 | 10 | 10.1002/clc.4960231012 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] The continuing applicability of the Killip classification system to the effective stratification of long-term and short-term outcome in patients with acute myocardial infarction (MI) and its influence on treatment strategy calls for reanalysis in the setting of today's primary reperfusion treatments. [HYPO... | null | 0.648 | 89 | Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,000 |
11,059,506 | Chiropractic through the eyes of physiotherapists, manual therapists, and osteopaths in The Netherlands. | Journal of alternative and complementary medicine (New York, N.Y.) | J Altern Complement Med | 6 | 5 | 10.1089/acm.2000.6.437 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] To identify current perceptions and levels of awareness of chiropractic among physiotherapists, osteopaths, and manual therapists in The Netherlands. In addition, to investigate how future communication and interprofessional collaboration between the four professions may be improved in the interests of pat... | null | 0.445 | 0 | Complementary and Alternative Medicine | Medicine | 2,000 |
11,059,438 | Outcomes of care and resource utilization among patients with knee or shoulder disorders treated by general internists, rheumatologists, or orthopedic surgeons. | The American journal of medicine | Am J Med | 108 | 1 | 10.1016/s0002-9343(99)00313-7 | eng | 2,000 | 1 | null | null | null | null | [PURPOSE] Previous studies have suggested that specialists may achieve better clinical outcomes for patients, albeit often at greater cost. We sought to compare outcomes of care and resource utilization among patients with shoulder or knee problems who were treated by general internists, rheumatologists, and orthopedic... | null | 1.609 | 262 | Medicine | Medicine | 2,000 |
11,058,492 | Open trial of psychodynamic psychotherapy for panic disorder: a pilot study. | The American journal of psychiatry | Am J Psychiatry | 157 | 11 | 10.1176/appi.ajp.157.11.1878 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] This report contains preliminary data from an open trial of brief psychodynamic psychotherapy for panic disorder. [METHOD] Fourteen patients with primary DSM-IV panic disorder completed a 24-session, twice-weekly course of psychodynamic psychotherapy. Other psychiatric treatment was not permitted throughout... | null | 3.887 | 405 | Psychiatry and Mental Health | Medicine | 2,000 |
11,057,748 | Effect of irradiation at the early fetal stage on adult brain function in the mouse: locomotor activity. | International journal of radiation biology | Int J Radiat Biol | 76 | 10 | 10.1080/09553000050151673 | eng | 2,000 | 10 | null | null | null | null | [PURPOSE] To study long-term changes in the adult locomotor activity of mice after exposure to gamma radiation at the early fetal stage of development. [MATERIALS AND METHODS] Pregnant Swiss albino mice were exposed locally on the abdominal area to a single dose of 0.25-1.5 Gy of 60Co gamma radiation at the dose rate o... | null | 1.055 | 104 | Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,000 |
11,057,703 | Children's experience of violence in China and Korea: a transcultural study. | Child abuse & neglect | Child Abuse Negl | 24 | 9 | 10.1016/s0145-2134(00)00175-7 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] There were two aims: First, to compare children's rates of being battered in home, by peers, and by teachers among students between China and Korea, and second, to identify particular risk factors for such violence. [METHODS] Children in grades four through six in Shanghai (238 cases) and Yanji (245 cases) ... | null | null | null | null | null | null |
11,056,768 | Cardiac marker point-of-care testing: evaluation of rapid on-site biochemical marker analysis for diagnosis of acute myocardial infarction. | Annals of the Academy of Medicine, Singapore | Ann Acad Med Singap | 29 | 4 | null | eng | 2,000 | 7 | null | null | null | null | [INTRODUCTION] Up to 40% of patients with acute myocardial infarction (AMI) present with non-diagnostic electrocardiograms (ECGs). The diagnosis in such cases is usually made with the aid of biochemical markers. Newer and more rapid assays for such markers have now enabled testing to be done on-site instead of in the l... | null | 0.199 | 70 | Medicine | Medicine | 2,000 |
11,056,593 | Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy: A randomized controlled trial. rhNGF Clinical Investigator Group. | JAMA | JAMA | 284 | 17 | 10.1001/jama.284.17.2215 | eng | 2,000 | 11 | 1 | null | null | null | [CONTEXT] Nerve growth factor is a neurotrophic factor that promotes the survival of small fiber sensory neurons and sympathetic neurons in the peripheral nervous system. Recombinant human nerve growth factor (rhNGF) has demonstrated efficacy as treatment for peripheral neuropathy in experimental models and phase 2 cli... | null | null | null | null | null | null |
11,056,592 | Assessing faculty financial relationships with industry: A case study. | JAMA | JAMA | 284 | 17 | 10.1001/jama.284.17.2209 | eng | 2,000 | 11 | 1 | null | null | null | [CONTEXT] A growing number of academic researchers receive industry funding for clinical and basic research, but little is known about the personal financial relationships of researchers with their industry sponsors. [OBJECTIVES] To assess the extent to which faculty researchers have personal financial relationships wi... | Biomedical and Behavioral Research; Empirical Approach; University of California, San Francisco | null | null | null | null | null |
11,056,445 | Hyperoxic reperfusion exacerbates postischemic renal dysfunction. | Surgery | Surgery | 128 | 5 | 10.1067/msy.2000.109117 | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND] Hyperoxic reperfusion from global ischemia worsens functional outcome because of oxygen radical-mediated injury. This study tested the hypothesis that hyperoxic reperfusion would exacerbate postischemic renal dysfunction. [METHODS] Twenty-nine healthy, uninephrectomized, male mongrel rabbits (Oryctolagus c... | null | null | null | null | null | null |
11,056,259 | Atypical hatching of a human blastocyst leading to monozygotic twinning: a case report. | Fertility and sterility | Fertil Steril | 74 | 5 | 10.1016/s0015-0282(00)01554-5 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] To report a case of monozygotic twinning after atypical hatching of a human blastocyst. [DESIGN] Case report. [SETTING] University-based IVF program. [PATIENT(S)] A 33-year-old woman with tubal sterility. [INTERVENTION(S)] Embryo transfer of a human blastocyst with atypical hatching. [MAIN OUTCOME MEASURE(S... | null | 1.515 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,000 |
11,055,756 | The impact of directly-observed treatment on the epidemiology of tuberculosis in Beijing. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | Int J Tuberc Lung Dis | 4 | 10 | null | eng | 2,000 | 10 | null | null | null | null | [SETTING] Fully supervised chemotherapy, or directly observed treatment (DOT), for newly detected smear-positive cases in Beijing, has been successfully implemented for two decades. [OBJECTIVE] To evaluate the progress made in tuberculosis control, and in particular to evaluate the impact of DOT on tuberculosis epidemi... | null | 1.022 | 124 | Infectious Diseases; Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,000 |
11,055,449 | The outcome and cost of alcohol and drug treatment in an HMO: day hospital versus traditional outpatient regimens. | Health services research | Health Serv Res | 35 | 4 | null | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To compare outcome and cost-effectiveness of the two primary addiction treatment options, day hospitals (DH) and traditional outpatient programs (OP) in a managed care organization, in a population large enough to examine patient subgroups. [DATA SOURCES] Interviews with new admissions to a large HMO's chem... | null | 1.351 | 149 | Health Policy | Medicine | 2,000 |
11,054,978 | Olanzapine-induced acute pancreatitis. | The Annals of pharmacotherapy | Ann Pharmacother | 34 | 10 | 10.1345/aph.19390 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To report the first published case of olanzapine-induced acute pancreatitis. [CASE SUMMARY] A 72-year-old white woman was admitted to the intensive care unit (ICU) with acute hemorrhagic pancreatitis and unintentional verapamil overdose. The patient did not consume alcohol and had undergone a cholecystectom... | null | 0.598 | 125 | Medicine; Pharmacology | Medicine | 2,000 |
11,054,384 | 5-HT(3) and histamine H(1) receptors mediate afferent nerve sensitivity to intestinal anaphylaxis in rats. | Gastroenterology | Gastroenterology | 119 | 5 | 10.1053/gast.2000.19461 | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND AND AIMS] The mechanisms underlying brain stem activation during antigen challenge have not been resolved. Our aim was to characterize afferent nerve responses to intestinal anaphylaxis and determine the mediators involved in afferent activation. [METHODS] Mesenteric afferent discharge was recorded electrop... | null | 3.483 | 482 | Gastroenterology | Medicine | 2,000 |
11,054,229 | Transcommissural valvuloplasty: technique and results. | Journal of vascular surgery | J Vasc Surg | 32 | 5 | 10.1067/mva.2000.111006 | eng | 2,000 | 11 | null | null | null | null | [PURPOSE] The purpose of this study was to describe the technique of a variation of closed external venous valve repair (transcommissural valvuloplasty), its complication rate, and duplex scan durability. [METHODS] The "blind" transcommissural valve repair of the vein was performed by placing transluminal sutures along... | null | 2.213 | 225 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,000 |
11,053,944 | The history is important in patients with suspected acute appendicitis. | Digestive surgery | Dig Surg | 17 | 4 | 10.1159/000018880 | eng | 2,000 | null | null | null | null | null | [BACKGROUND/AIMS] The clinical diagnosis of acute appendicitis is incorrect in 20-30% of patients undergoing surgery. We analysed the clinical importance of nine commonly used symptoms and signs in 544 consecutive patients with regard to the correct diagnosis of acute appendicitis. [METHODS] Open population-based prosp... | null | 0.351 | 80 | Gastroenterology; Surgery | Medicine | 2,000 |
11,053,821 | Does aprotinin reduce lung reperfusion damage after cardiopulmonary bypass? | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | Eur J Cardiothorac Surg | 18 | 5 | 10.1016/s1010-7940(00)00518-2 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] The role of aprotinin in the prevention of lung reperfusion injury was investigated in the patients undergoing cardio-pulmonary bypass (CPB) for coronary artery bypass grafting (CABG) operations. [METHODS] The study was planned randomly and prospectively. Two hundred milliliters of physiological saline solu... | null | 0.86 | 158 | Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
11,052,517 | Functional outcomes in patients with mucosal ulcerative colitis after ileal pouch-anal anastomosis by the double stapling technique: is there a relation to tissue type? | Diseases of the colon and rectum | Dis Colon Rectum | 43 | 10 | 10.1007/BF02236636 | eng | 2,000 | 10 | null | null | null | null | [PURPOSE] The aim of this study was to evaluate any differences in functional outcome in patients with mucosal ulcerative colitis after restorative proctocolectomy and ileal pouch-anal anastomosis with use of the double stapling technique relative to the type of tissue in the stapled doughnut. [METHODS] Between Septemb... | null | 1.294 | 185 | Gastroenterology; Medicine | Medicine | 2,000 |
11,051,374 | Impact of KRAS and TP53 mutations on survival in patients with left- and right-sided Dukes' C colon cancer. | The American journal of gastroenterology | Am J Gastroenterol | 95 | 10 | 10.1111/j.1572-0241.2000.02327.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] It has been suggested that KRAS and TP53 mutated tumors might influence the phenotypic behavior of left- and right-sided colon tumors. We investigated the incidence of these mutations in left- and right-sided colon tumors and their possible influence on survival in a homogeneous group of patients with Dukes... | null | 1.058 | 296 | Gastroenterology; Hepatology | Medicine | 2,000 |
11,051,351 | Clinically significant gastrointestinal bleeding in critically ill patients in an era of prophylaxis. | The American journal of gastroenterology | Am J Gastroenterol | 95 | 10 | 10.1111/j.1572-0241.2000.03189.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] Clinical studies examining stress-related gastrointestinal bleeding in critically ill patients vary in their clinical definitions and assessment of clinical significance. Although there is evidence that routine prophylaxis decreases stress-related gastrointestinal bleeding, recent studies indicate a decreas... | null | 1.058 | 296 | Gastroenterology; Hepatology | Medicine | 2,000 |
11,051,340 | Application of topographical methods to clinical esophageal manometry. | The American journal of gastroenterology | Am J Gastroenterol | 95 | 10 | 10.1111/j.1572-0241.2000.03178.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] Topographical manometric methods have improved the understanding of esophageal peristalsis in research applications but require a large number of recording sensors. Commonly used methods limited to four sensors were compared to topographical methods to determine whether the latter also had significant clini... | null | 1.058 | 296 | Gastroenterology; Hepatology | Medicine | 2,000 |
11,049,097 | Validity of the hospital discharge diagnosis in epidemiologic studies of biliopancreatic pathology. PANKRAS II Study Group. | European journal of epidemiology | Eur J Epidemiol | 16 | 6 | 10.1023/a:1007692408457 | eng | 2,000 | 6 | null | null | null | null | [BACKGROUND] The aim was to analyse the magnitude, direction and predictors of change in the main hospital discharge diagnosis (HDD) after a clinical expert review, among patients included in a multicentre molecular epidemiologic study of biliopancreatic diseases. [METHODS] A total of 602 patients with a suspicion diag... | null | null | null | null | null | null |
11,049,014 | The consumption of drugs by 75-year-old individuals living in their own homes. | European journal of clinical pharmacology | Eur J Clin Pharmacol | 56 | 6-7 | 10.1007/s002280000157 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To examine the drug consumption and the extent of polypharmacy (defined as daily intake of three or more drugs) among 75-year-old persons living in their own homes and to point out potential problems associated with it. [METHODS] Information on the intake of all drugs was collected from 492 subjects randoml... | null | 0.632 | 126 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,000 |
11,048,955 | Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond. | Chemistry & biology | Chem Biol | 7 | 8 | 10.1016/s1074-5521(00)00005-3 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] The microscopic events of ribonuclease (RNase) catalyzed phosphoryl transfer reactions are still a matter of debate in which the contenders adhere to either the classical concerted acid-base mechanism or a more sequential triester-like mechanism. In the case of RNase A, small thio-effects of the nonbridgin... | null | null | null | null | null | null |
11,046,201 | Role of pump prime in the etiology and pathogenesis of cardiopulmonary bypass-associated acidosis. | Anesthesiology | Anesthesiology | 93 | 5 | 10.1097/00000542-200011000-00006 | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND] The development of metabolic acidosis during cardiopulmonary bypass (CPB) is well recognized but poorly understood. The authors hypothesized that the delivery of pump prime fluids is primarily responsible for its development. Accordingly, acid-base changes induced by the establishment of CPB were studied u... | null | null | null | null | null | null |
11,045,854 | Heritability of the blood pressure response to acute ethanol exposure in five inbred strains of mice. | Alcoholism, clinical and experimental research | Alcohol Clin Exp Res | 24 | 10 | null | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] Chronic alcohol consumption is a major risk factor for hypertension. There is evidence in humans that the susceptibility to alcohol-related hypertension may vary based on genotype. As a first step in investigating the genetic basis for alcohol-related hypertension, the current study was designed to assess ... | null | null | null | null | null | null |
11,045,651 | Rapamycin induces transforming growth factor-beta production by lymphocytes. | Transplantation | Transplantation | 70 | 7 | 10.1097/00007890-200010150-00020 | eng | 2,000 | 10 | 15 | null | null | null | [BACKGROUND] Under certain conditions rapamycin and transforming growth factor- (TGF) beta have similar immunoregulatory effects, suggesting a potential functional link between rapamycin and TGF-beta. [METHODS] Splenic leukocytes were stimulated in vitro with anti-CD3 or with allogeneic cells in vivo in the presence or... | null | 2.115 | 224 | Transplantation | Medicine | 2,000 |
11,045,640 | Pharmacodynamics of mycophenolic acid in heart allograft recipients: correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology. | Transplantation | Transplantation | 70 | 7 | 10.1097/00007890-200010150-00009 | eng | 2,000 | 10 | 15 | null | null | null | [BACKGROUND] Assays of drug blood levels are used for therapeutic immunosuppressive drug monitoring (pharmacokinetics, PK). We monitored lymphocyte functions (pharmacodynamics, PD) in allograft recipients treated with mycophenolic acid (MPA) to determine its mechanisms and the relationships among dose levels, PK, PD, a... | null | 2.115 | 224 | Transplantation | Medicine | 2,000 |
11,044,222 | Salutary role for angiotensin in partial urinary tract obstruction. | Kidney international | Kidney Int | 58 | 5 | 10.1111/j.1523-1755.2000.00374.x | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND] In the neonatal period, angiotensin II (Ang II) is up-regulated and induces a timely development of the renal pelvis and ureteral peristalsis, thereby protecting the kidney from hydronephrosis. We tested the possibility that in adulthood, Ang II may act salutarily on the kidney structure during partial uri... | null | null | null | null | null | null |
11,044,205 | Citrate therapy for polycystic kidney disease in rats. | Kidney international | Kidney Int | 58 | 5 | 10.1111/j.1523-1755.2000.00357.x | eng | 2,000 | 11 | null | null | null | null | [BACKGROUND] Few treatments are available to slow the progression to renal failure in autosomal dominant polycystic kidney disease (PKD). In an animal model of PKD, the male heterozygous Han:SPRD rat, intake of a solution of potassium citrate plus citric acid (KCitr) from age one to three months prevented a decline in ... | null | null | null | null | null | null |
11,042,758 | Access to substance abuse treatment services under the Oregon Health Plan. | JAMA | JAMA | 284 | 16 | 10.1001/jama.284.16.2093 | eng | 2,000 | 10 | 25 | null | null | null | [CONTEXT] The shift to Medicaid managed care has raised numerous concerns about access to publicly funded substance abuse treatment. The implementation of a capitated chemical dependency benefit within the Oregon Health Plan in 1995 provided an opportunity to study the impact of funding mechanisms on access. [OBJECTIVE... | null | null | null | null | null | null |
11,042,703 | Growth in the first year in children following IAP Policy on Infant Feeding. | Indian pediatrics | Indian Pediatr | 37 | 10 | null | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To study the growth pattern in the first year in children fed according to recommendations of IAP Policy on Infant Feeding. [DESIGN] Longitudinal. [SETTING] Department of Pediatrics, S.C.B. Medical College Hospital, Cuttack, Orissa. [SUBJECTS AND METHODS] 114 infants (68 boys and 46 girls) with birth weight... | null | 0.203 | 63 | Pediatrics, Perinatology and Child Health | Medicine | 2,000 |
11,041,466 | Fibrin sheath stripping versus catheter exchange for the treatment of failed tunneled hemodialysis catheters: randomized clinical trial. | Journal of vascular and interventional radiology : JVIR | J Vasc Interv Radiol | 11 | 9 | 10.1016/s1051-0443(07)61351-7 | eng | 2,000 | 10 | null | null | null | null | [PURPOSE] To compare the effectiveness of two treatments for tunneled hemodialysis catheter malfunction: percutaneous fibrin sheath stripping (PFSS) and over-the-wire catheter exchange (EX). [MATERIALS AND METHODS] Adult patients with poorly functioning tunneled hemodialysis catheters (flow rates < 200 mL/min) were ran... | null | 1.111 | 150 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
11,041,310 | Patterns of opiate use in a heroin maintenance programme. | Psychopharmacology | Psychopharmacology (Berl) | 152 | 1 | 10.1007/s002130000492 | eng | 2,000 | 9 | null | null | null | null | [RATIONALE] Little is known about patterns of opiate use by heroin addicts. [OBJECTIVES] To describe opiate use over time among heroin addicts who had access to legally prescribed intravenous heroin and oral opiates. [METHODS] Analysis of daily drug administration records of 37 patients enrolled in the Geneva heroin ma... | null | 1.409 | 218 | Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,000 |
11,040,190 | Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum. | Gastroenterology | Gastroenterology | 119 | 4 | 10.1053/gast.2000.18147 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND AND AIMS] Substance P, a member of the tachykinin family, is a prosecretory neuropeptide distributed widely throughout the enteric nervous system. Implicated in inflammatory states, its role in enterotoxigenic water and electrolyte secretion is unclear. We assessed the effect of substance P antagonists and ... | null | 3.483 | 482 | Gastroenterology | Medicine | 2,000 |
11,039,741 | Conjunctival dysfunction and mitomycin C-induced hypotony. | Journal of glaucoma | J Glaucoma | 9 | 5 | 10.1097/00061198-200010000-00008 | eng | 2,000 | 10 | null | null | null | null | [PURPOSE] To determine the role of a physically intact conjunctiva in the development of chronic hypotony after mitomycin C-enhanced trabeculectomy. [METHOD] Three patients with mitomycin C-related hypotonic maculopathy, but without a leak on Siedel test, had a thorough evaluation of the bleb area and an anterior segme... | null | 1.308 | 105 | Ophthalmology | Medicine | 2,000 |
11,039,554 | Effect of all-trans and 9-cis retinoic acid on growth and metastasis of xenotransplanted canine osteosarcoma cells in athymic mice. | American journal of veterinary research | Am J Vet Res | 61 | 10 | 10.2460/ajvr.2000.61.1241 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To determine effects of all-trans and 9-cis retinoic acid (RA) on tumor growth and metastatic ability of canine osteosarcoma cells transplanted into athymic (nude) mice. [ANIMALS] Forty-five 5-week-old female BALB/c nude mice. [PROCEDURE] 1 X 10(7) POS osteosarcoma cells were transplanted subcutaneously int... | null | 0.796 | 105 | Medicine; Veterinary | Medicine; Veterinary | 2,000 |
11,039,415 | Results of macular hole surgery in patients over 80 years of age. | Retina (Philadelphia, Pa.) | Retina | 20 | 5 | 10.1097/00006982-200009000-00001 | eng | 2,000 | null | null | null | null | null | [PURPOSE] To evaluate the results of macular hole surgery in patients over 80 years of age to determine if surgery is beneficial in an elderly patient population. [METHODS] Twenty consecutive patients over age 80 with idiopathic macular holes and 20 nonconsecutive controls younger than 80 years treated for idiopathic m... | null | 0.771 | 149 | Medicine; Ophthalmology | Medicine | 2,000 |
11,038,300 | Glycation induced crosslinking of link proteins, in vivo and in vitro. | The Journal of surgical research | J Surg Res | 94 | 1 | 10.1006/jsre.2000.6000 | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] Reducing sugars have the ability to crosslink proteins through creation of advanced glycosylated end products (AGE). In this study, we determined the ability of AGE to induce crosslinking of link proteins and aggrecan proteoglycans. [METHODS] Aggrecan proteoglycans and link proteins were purified from adult... | null | 0.786 | 131 | Surgery | Medicine | 2,000 |
11,037,894 | Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs. | Arthritis and rheumatism | Arthritis Rheum | 43 | 10 | 10.1002/1529-0131(200010)43:10<2335::AID-ANR22>3.0.CO;2-W | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To test for linkage between the HLA region and juvenile rheumatoid arthritis (JRA), with stratification by onset and course types, in a cohort of affected sibling pairs (ASPs). [METHODS] Eighty pairs of siblings with JRA who were registered with the Research Registry for JRA ASPs (sponsored by the National ... | null | null | null | null | null | null |
11,037,842 | Accuracy, utility, and cost of frozen section margins in head and neck cancer surgery. | The Laryngoscope | Laryngoscope | 110 | 10 Pt 1 | 10.1097/00005537-200010000-00039 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] Intraoperative frozen section analysis of surgical margins is widely used in head and neck cancer surgery. This study evaluates frozen section accuracy relative to permanent controls and final margins from the entire specimen, the rate at which frozen sections impact intraoperative management, and the resu... | null | 1.349 | 183 | Otorhinolaryngology | Medicine | 2,000 |
11,037,839 | New options for aerodigestive tract replacement after extended pharyngolaryngectomy. | The Laryngoscope | Laryngoscope | 110 | 10 Pt 1 | 10.1097/00005537-200010000-00036 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] Assess the results of a new type of reconstruction of the aerodigestive tract after extended pharyngolaryngectomy. [STUDY DESIGN] Follow-up of a total of eight patients who had surgery using ileocolic free graft. [METHODS] The surgical technique is described. Five patients underwent pharyngolaryngectomy/ce... | null | 1.349 | 183 | Otorhinolaryngology | Medicine | 2,000 |
11,037,301 | Sickness absence with psychiatric disorders--an increased risk for marginalisation among men? | Social psychiatry and psychiatric epidemiology | Soc Psychiatry Psychiatr Epidemiol | 35 | 8 | 10.1007/s001270050247 | eng | 2,000 | 8 | null | null | null | null | [BACKGROUND] Sickness absence with psychiatric disorders is a major public health problem with serious consequences for the individual, the employer and society. The aim was to assess the occurrence of psychiatric sickness absence with special focus on sex differences. [METHODS] A nationwide sickness insurance register... | null | 1.293 | 152 | Health; Psychiatry and Mental Health; Social Psychology; Epidemiology | Medicine; Psychology; Social Sciences | 2,000 |
11,035,822 | Carotid artery distensibility and cardiac function in adolescents with type 1 diabetes. | The Journal of pediatrics | J Pediatr | 137 | 4 | 10.1067/mpd.2000.109002 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To determine the presence and correlates of early heart and blood vessel dysfunction in adolescents with type 1 diabetes mellitus (DM) of relatively short duration. [STUDY DESIGN] A total of 33 patients with DM (20 male, mean age 15.8 +/- 1.3 years, mean DM duration 9.3 +/- 3.9 years) and 16 healthy subject... | null | 1.544 | 246 | Pediatrics, Perinatology and Child Health | Medicine | 2,000 |
11,035,820 | Delayed diagnoses of Turner's syndrome: proposed guidelines for change. | The Journal of pediatrics | J Pediatr | 137 | 4 | 10.1067/mpd.2000.107390 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To measure the delays in diagnosis of Turner's syndrome (TS) and to propose strategies for earlier screening and diagnosis. [METHODS] The medical records of 81 girls with TS were reviewed for age at diagnosis, reason(s) for karyotype analysis, and clinical features including growth failure. Delay in diagnos... | null | 1.544 | 246 | Pediatrics, Perinatology and Child Health | Medicine | 2,000 |
11,035,569 | Neonatal bilirubin testing practices: reports from 312 laboratories enrolled in the Colege of American Pathologists Excel Proficiency Testing Program. | Archives of pathology & laboratory medicine | Arch Pathol Lab Med | 124 | 10 | 10.5858/2000-124-1425-NBTP | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To characterize laboratory practices for neonatal bilirubin testing and to identify opportunities for improvement. [DESIGN] A voluntary self-assessment questionnaire was used to assess the laboratory practices of 312 laboratories subscribing to the College of American Pathologists (CAP) Excel Chemistry Prof... | null | null | null | null | null | null |
11,035,533 | Pupillography as an objective indicator of fatigue. | Current eye research | Curr Eye Res | 21 | 1 | null | eng | 2,000 | 7 | null | null | null | null | [PURPOSE] To determine whether parameters calculated from pupillary activity can identify subjects with sleep deprivation, and whether the objective values correlate with a subjective feeling of fatigue. [METHODS] pupil size in the dark was recorded continuously for 10 minutes in 12 healthy volunteers using an infrared... | null | 0.831 | 94 | Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience | Medicine; Neuroscience | 2,000 |
11,035,347 | The fate of rectus fascia suburethral slings. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 183 | 4 | 10.1067/mob.2000.107091 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] Autologous rectus fascia is commonly used to construct suburethral slings for the treatment of genuine stress incontinence. This fascia performs well and has not been associated with clinical problems related to its choice as a sling material. However, the histologic appearance of such slings after implanta... | null | 1.624 | 274 | Obstetrics and Gynecology | Medicine | 2,000 |
11,034,030 | Effect of placement of a speech appliance on levator veli palatini muscle activity during speech. | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association | Cleft Palate Craniofac J | 37 | 5 | 10.1597/1545-1569_2000_037_0478_eopoas_2.0.co_2 | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] The purposes of this electromyographic study were to examine whether levator veli palatini muscle activity during speech can be changed with placement of a speech appliance and to clarify whether or not the change is related to the type of speech appliance used. [DESIGN] Electromyography (EMG) was performed... | null | 0.685 | 96 | Oral Surgery; Otorhinolaryngology | Dentistry; Medicine | 2,000 |
11,033,188 | Oxygen tension in primary gynaecological tumours: the influence of carbon dioxide concentration. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | Radiother Oncol | 57 | 1 | 10.1016/s0167-8140(00)00277-2 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND AND PURPOSE] To assess the effect of inhalation of various high oxygen content gases (HOCG) with different carbon dioxide concentrations on the tumour oxygen tension in patients with primary gynaecological malignancies. [MATERIALS AND METHODS] Tumour oxygen tension was assessed on two protocols in those pat... | null | 1.283 | 189 | Hematology; Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
11,033,108 | The role of L-type calcium current in the generation of repolarization-induced contraction in cardiac myocytes. | Cardiovascular research | Cardiovasc Res | 48 | 1 | 10.1016/s0008-6363(00)00148-6 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] Early experiments into the arrhythmogenic transient inward current frequently showed apparent coupling of this current to repolarization from a depolarizing voltage clamp step. Calcium transients have subsequently been shown to couple to such repolarization and are the result of calcium release from the sar... | null | null | null | null | null | null |
11,032,597 | Phase I and pharmacokinetic study of docetaxel and irinotecan in patients with advanced solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Clin Oncol | 18 | 20 | 10.1200/JCO.2000.18.20.3545 | eng | 2,000 | 10 | 15 | null | null | null | [PURPOSE] We conducted a phase I and pharmacokinetic study of docetaxel in combination with irinotecan to determine the dose-limiting toxicity (DLT), the maximum-tolerated dose (MTD), and the dose at which at least 50% of the patients experienced a DLT during the first cycle, and to evaluate the safety and pharmacokine... | null | 3.972 | 646 | Cancer Research; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,031,152 | Quantifying the literature of computer-aided instruction in medical education. | Academic medicine : journal of the Association of American Medical Colleges | Acad Med | 75 | 10 | 10.1097/00001888-200010000-00021 | eng | 2,000 | 10 | null | null | null | null | [PURPOSE] To characterize the literature about computer-aided instruction (CAI) as it relates to medical education. [METHOD] A descriptive study using the Medline and ERIC databases, reviewing articles pertaining to CAI for medical professionals. The literature was evaluated with respect to type of article, journal, la... | null | 0.742 | 199 | Education; Medicine | Medicine; Social Sciences | 2,000 |
11,030,498 | Sleep apnea syndrome in chronic spinal cord injury: associated factors and treatment. | Archives of physical medicine and rehabilitation | Arch Phys Med Rehabil | 81 | 10 | 10.1053/apmr.2000.9398 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To determine the prevalence of sleep apnea in a sample of persons with chronic spinal cord injury (SCI) of varying injury levels and degrees of impairment. [DESIGN] Cross-sectional study. [SETTING] Inpatient SCI rehabilitation unit. [PARTICIPANTS] Twenty men with SCI (motor complete and incomplete; American... | null | 0.838 | 225 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science | Health Professions; Medicine | 2,000 |
11,030,497 | Acquisition versus retrieval deficits in traumatic brain injury: implications for memory rehabilitation. | Archives of physical medicine and rehabilitation | Arch Phys Med Rehabil | 81 | 10 | 10.1053/apmr.2000.9390 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To examine whether impaired memory in persons with traumatic brain injury (TBI) is caused by impaired initial acquisition or compromised retrieval from long-term storage. [DESIGN] Prospective matched controlled trial. [SETTING] Postacute rehabilitation institute. [PARTICIPANTS] Patients with moderate to sev... | null | 0.838 | 225 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science | Health Professions; Medicine | 2,000 |
11,030,376 | Anti-FcepsilonRIalpha serum autoantibodies in different subtypes of urticaria. | Allergy | Allergy | 55 | 10 | 10.1034/j.1398-9995.2000.00445.x | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] In recent years, a histamine-releasing anti-FcepsilonRIalpha autoantibody has been demonstrated in about one-third of patients with chronic urticaria. However, its clinical significance is still unclear. The objective was to detect a possible correlation between the occurrence of the anti-FcepsilonRIalpha ... | null | 0.882 | 213 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,000 |
11,030,277 | Body composition and growth in asthmatic children treated with inhaled steroids. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | Ann Allergy Asthma Immunol | 85 | 3 | 10.1016/S1081-1206(10)62470-2 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Prolonged treatment with inhaled steroids is recommended for long-term control of asthma in children; however, it can interfere with growth and body composition. [OBJECTIVE] The aim of this study is to answer the question whether 6 months treatment with inhaled steroids causes body fat accumulation and gro... | null | null | null | null | null | null |
11,030,187 | Incidence of post-endoscopic retrograde-cholangiopancreatography/sphincterotomy pancreatitis depends upon definition criteria. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver | Dig Liver Dis | 32 | 5 | 10.1016/s1590-8658(00)80262-5 | eng | 2,000 | null | null | null | null | null | [BACKGROUND] The reported incidence of post-endoscopic retrograde-cholangiopancreatography/sphincterotomy pancreatitis ranges between 1.3% and 12.8%. This may likely reflect different definitions of pancreatitis and methods of data collection, rather than differences in patient populations, indications and endoscopic e... | null | 0.398 | 113 | Gastroenterology; Hepatology | Medicine | 2,000 |
11,030,184 | Left ventricular volumes in liver cirrhosis. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver | Dig Liver Dis | 32 | 5 | 10.1016/s1590-8658(00)80259-5 | eng | 2,000 | null | null | null | null | null | [BACKGROUND] Patients with alcoholic cirrhosis have left ventricular dimensions similar to controls. Few data have been reported in patients with cirrhosis of viral origin. [AIM] To assess left ventricular dimensions in patients with pure viral cirrhosis. [PATIENTS AND METHODS] Thirty patients with virus-related cirrho... | null | 0.398 | 113 | Gastroenterology; Hepatology | Medicine | 2,000 |
11,028,831 | Effect of tropisetron on circulating catecholamines and other putative biochemical markers in serum of patients with fibromyalgia. | Scandinavian journal of rheumatology. Supplement | Scand J Rheumatol Suppl | 113 | null | 10.1080/030097400446634 | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] The aim of the study was to assess the influence of the 5HT3-receptor antagonist tropisetron on circulating catecholamines as biochemical markers of the activity of the sympathoadrenal system in fibromyalgia. Moreover, serum concentrations of serotonin, somatomedin C, oxytocin, calcitonin-gene-related-pepti... | null | null | null | null | null | null |
11,028,732 | Effects of oxygen and nitric oxide inhalation in a porcine model of recurrent microembolism. | Acta anaesthesiologica Scandinavica | Acta Anaesthesiol Scand | 44 | 9 | 10.1034/j.1399-6576.2000.440913.x | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] Inhalation of nitric oxide (iNO) has been proposed for the treatment of acute pulmonary embolism. The present study evaluates the effects of oxygen (O2) and nitric oxide inhalation in a porcine model of sustained pulmonary hypertension induced by recurrent pulmonary microembolism. [METHODS] Twelve pigs wer... | null | 0.896 | 126 | Anesthesiology and Pain Medicine; Medicine | Medicine | 2,000 |
11,028,570 | Postpartum depression: identification of women at risk. | BJOG : an international journal of obstetrics and gynaecology | BJOG | 107 | 10 | 10.1111/j.1471-0528.2000.tb11609.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To identify and test the predictive power of demographic, obstetric, and psychosocial risk factors of postpartum depression. [DESIGN] Community-based, prospective follow up study based on questionnaires on past history of psychiatric disease, psychological distress and social support during pregnancy and de... | null | 1.395 | 195 | Obstetrics and Gynecology | Medicine | 2,000 |
11,028,143 | Unjustified variations in patient management for acute myocardial infarction in the Rhône-Alpes region of France. PRIMA Group. | International journal of technology assessment in health care | Int J Technol Assess Health Care | 16 | 3 | 10.1017/s0266462300102156 | eng | 2,000 | null | null | null | null | null | [OBJECTIVES] To examine determinants of use of cardiac procedures after acute myocardial infarction and identify variation factors. [METHODS] Observational prospective cohort study of 2,519 patients in 48 centers with a two-level logistic-regression analysis. [RESULTS] Elderly patients were less likely to undergo pre- ... | Empirical Approach; Health Care and Public Health | 0.554 | 79 | Health Policy | Medicine | 2,000 |
11,028,137 | Estimating the microvascular benefits of screening for type 2 diabetes mellitus. | International journal of technology assessment in health care | Int J Technol Assess Health Care | 16 | 3 | 10.1017/s0266462300102090 | eng | 2,000 | null | null | null | null | null | [OBJECTIVE] To define the relative benefits of screening for diabetes and improved treatment programs and ways of improving the efficiency of screening for a population-based cohort derived from the Third National Health and Nutrition Examination Survey (NHANES III). [METHODS] A Markov decision model is used to estimat... | null | 0.554 | 79 | Health Policy | Medicine | 2,000 |
11,025,768 | The effect of halofuginone, an inhibitor of collagen type i synthesis, on urethral stricture formation: in vivo and in vitro study in a rat model. | The Journal of urology | J Urol | 164 | 5 | null | eng | 2,000 | 11 | null | null | null | null | [PURPOSE] Urethral strictures are narrowing of the urethra caused by fibrosis due to excessive collagen production in response to an insult. We evaluated the effects of halofuginone, a potent inhibitor of collagen alpha1(I) gene expression, on experimentally induced urethral strictures in vivo and on rat urethral fibro... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
11,025,717 | Value of routine evaluation of the voiding phase when performing urodynamic testing in women with lower urinary tract symptoms. | The Journal of urology | J Urol | 164 | 5 | null | eng | 2,000 | 11 | null | null | null | null | [PURPOSE] Lower urinary tract symptoms in women are often evaluated by cystometrography. We only assessed the bladder response to filling and not the impact of abnormal voiding, which is known to cause lower urinary tract symptoms. We determined the prevalence of voiding abnormalities in women with lower urinary tract ... | null | 1.751 | 291 | Urology | Medicine | 2,000 |
11,024,384 | Mid-term results of the valve-on-valve technique for bioprosthetic failure. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | Eur J Cardiothorac Surg | 18 | 4 | 10.1016/s1010-7940(00)00509-1 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] Redo operations for bioprosthesis malfunction can sometimes be technically very demanding and cardiac structures may be damaged. Excising only the leaflets of the damaged bioprosthesis and leaving the old ring in situ on which the 'new' mechanical valve is sutured can, in very selected cases, represent a so... | null | 0.86 | 158 | Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
11,024,375 | Endothelial function of human vena saphena magna prepared with different minimally invasive harvesting techniques. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | Eur J Cardiothorac Surg | 18 | 4 | 10.1016/s1010-7940(00)00549-2 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] Minimally invasive saphenous harvesting techniques have been shown to reduce post-operative morbidity. However, when applying new techniques of vein harvesting, endothelial integrity should be preserved in order to guarantee graft quality. We investigated the impact of two different minimally invasive saph... | null | 0.86 | 158 | Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
11,023,143 | Intentional weight loss and mortality among overweight individuals with diabetes. | Diabetes care | Diabetes Care | 23 | 10 | 10.2337/diacare.23.10.1499 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To estimate the effect of intentional weight loss on mortality in overweight individuals with diabetes. [RESEARCH DESIGN AND METHODS] We performed a prospective analysis with a 12-year mortality follow-up (1959-1972) of 4,970 overweight individuals with diabetes, 40-64 years of age, who were enrolled in the... | null | 2.422 | 433 | Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine; Nursing | 2,000 |
11,023,007 | Nutritional contribution of eggs to American diets. | Journal of the American College of Nutrition | J Am Coll Nutr | 19 | 5 Suppl | 10.1080/07315724.2000.10718980 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] The main purposes of this study were (1) to assess the nutritional significance of eggs in the American diet and (2) to estimate the degree of association between egg consumption and serum cholesterol concentration. [METHODS] Data from the most recent National Health and Nutritional Examination Survey (NHA... | null | 0.552 | 0 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,000 |
11,022,991 | Primary spontaneous pneumothorax: treatment practices in Australia. | Respirology (Carlton, Vic.) | Respirology | 5 | 3 | 10.1046/j.1440-1843.2000.00264.x | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] The aim of the present study was to determine treatment practices for spontaneous pneumothorax (PTX) in Australia. [METHODOLOGY] A questionnaire regarding treatment of PTX was posted to all medically qualified members of the Thoracic Society of Australia and New Zealand resident in Australia. [RESULTS] Fift... | null | 0.165 | 113 | Pulmonary and Respiratory Medicine | Medicine | 2,000 |
11,022,772 | Evaluation of a new bioabsorbable barrier for recession therapy: a feasibility study. | Journal of periodontology | J Periodontol | 71 | 9 | 10.1902/jop.2000.71.9.1433 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] The objective of this study was to evaluate the feasibility of a new polylactic acid bioabsorbable barrier in the treatment of gingival recession. [METHODS] Twenty patients with buccal recession defects (Miller class I, II, and III; mean recession: 4.0 +/- 1.2 mm; range: 2.0 to 6.8 mm) participated. After ... | null | 0.952 | 186 | Periodontics | Dentistry | 2,000 |
11,022,400 | Association and linkage studies of candidate genes involved in GABAergic neurotransmission in lithium-responsive bipolar disorder. | Journal of psychiatry & neuroscience : JPN | J Psychiatry Neurosci | 25 | 4 | null | eng | 2,000 | 9 | null | null | null | null | [OBJECTIVE] To test for genetic linkage and association with GABAergic candidate genes in lithium-responsive bipolar disorder. [DESIGN] Polymorphisms located in genes that code for GABRA3, GABRA5 and GABRB3 subunits of the GABAA receptor were investigated using association and linkage strategies. [PARTICIPANTS] A total... | null | null | null | null | null | null |
11,022,205 | Percutaneous coronary intervention in the elderly: a comparison of procedural and clinical outcomes between the eighth and ninth decades. | The Journal of invasive cardiology | J Invasive Cardiol | 12 | 10 | null | eng | 2,000 | 10 | null | null | null | null | [AIMS] To compare short-term safety and outcome of percutaneous coronary intervention (PCI) in the elderly in their ninth decade with those in their eighth decade. [METHODS] Five-hundred and eighty-nine patients aged 70 years undergoing coronary angioplasty were stratified into two groups, those 80 years old (Group 1, ... | null | 0.305 | 66 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
11,022,085 | Extracellular pH, Ca(2+) influx, and response of vascular smooth muscle cells to 5-hydroxytryptamine. | Stroke | Stroke | 31 | 10 | 10.1161/01.str.31.10.2500 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND AND PURPOSE] Cerebral vascular smooth muscle cells (VSMCs) contract on extracellular pH (pH(o)) increases and relax on pH(o) decreases. These changes in tone are believed to result from changes in [Ca(2+)](i), although the responsible mechanisms are not fully understood. VSMCs also contract in response to 5... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
11,020,848 | Association between common bile duct stones and treated hypothyroidism. | Hepato-gastroenterology | Hepatogastroenterology | 47 | 34 | null | eng | 2,000 | null | null | null | null | null | [BACKGROUND/AIMS] The purpose of this study was to investigate the frequency of diagnosed hypothyroidism in patients with common bile duct stones. [METHODOLOGY] The common bile duct stone group (Group I) consisted of all the patients who had verified gallstones in the common bile duct in endoscopic retrograde cholangio... | null | 0.504 | 84 | Gastroenterology; Medicine; Hepatology | Medicine | 2,000 |
11,020,759 | Effects of isoflurane, sevoflurane, and halothane on myofilament Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in rat ventricular myocytes. | Anesthesiology | Anesthesiology | 93 | 4 | 10.1097/00000542-200010000-00027 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] The aim of this study was to describe and compare the effects of isoflurane, sevoflurane, and halothane at selected concentrations (i.e., concentrations that led to equivalent depression of the electrically evoked Ca2+ transient) on myofilament Ca2+ sensitivity, sarcoplasmic reticulum (SR) Ca2+ content, an... | null | null | null | null | null | null |
11,020,748 | Transcranial Doppler ultrasonography as a screening technique for detection of a patent foramen ovale before surgery in the sitting position. | Anesthesiology | Anesthesiology | 93 | 4 | 10.1097/00000542-200010000-00016 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] Venous air embolism has been reported to occur in 23-45% of patients undergoing neurosurgical procedures in the sitting position. If venous air embolism occurs, a patent foramen ovale (PFO) is a risk factor for paradoxical air embolism and its sequelae. Preoperative screening for a PFO is therefore recomme... | null | null | null | null | null | null |
11,020,615 | Diffuse lamellar keratitis associated with epithelial defects after laser in situ keratomileusis. | Journal of cataract and refractive surgery | J Cataract Refract Surg | 26 | 9 | 10.1016/s0886-3350(00)00570-8 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] To describe the association between the presence of epithelial defects and the development of diffuse lamellar keratitis (DLK), "Sands of the Sahara" syndrome, following laser in situ keratomileusis (LASIK). [SETTING] Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texa... | null | 1.883 | 169 | Ophthalmology; Sensory Systems; Surgery | Medicine; Neuroscience | 2,000 |
11,020,613 | Surgical correction of severe myopia with an angle-supported phakic intraocular lens. | Journal of cataract and refractive surgery | J Cataract Refract Surg | 26 | 9 | 10.1016/s0886-3350(00)00543-5 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] To evaluate the effectiveness, predictability, and safety of a fourth-generation angle-supported anterior chamber phakic intraocular lens (IOL) in patients with severe myopia. [SETTING] Refractive Surgery and Cornea Unit, Alicante Institute of Ophthalmology, Miguel Hernández University School of Medicine, Ali... | null | 1.883 | 169 | Ophthalmology; Sensory Systems; Surgery | Medicine; Neuroscience | 2,000 |
11,020,507 | Analysis of 104 twin pregnancies conceived with assisted reproductive technologies and 193 spontaneously conceived twin pregnancies. | Fertility and sterility | Fertil Steril | 74 | 4 | 10.1016/s0015-0282(00)01491-6 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVE] To evaluate pregnancy outcome of assisted reproductive technology (ART)-conceived twin pregnancies. [DESIGN] Retrospective study. [SETTING] A tertiary obstetric care center. [PATIENT(S)] All twin pregnancies delivered > or = 24 weeks of gestation from January 1, 1996, to December 31, 1997. [INTERVENTION(S)]... | null | 1.515 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,000 |
11,020,107 | Visual field defects in children with congenital glaucoma. | Journal of pediatric ophthalmology and strabismus | J Pediatr Ophthalmol Strabismus | 37 | 5 | null | eng | 2,000 | null | null | null | null | null | [PURPOSE] To determine visual field defects in a cohort of children with congenital glaucoma. [METHODS] Monocular visual fields were measured in 24 meridians for targets V4e, I4e, I2e, and I1e, using a Goldmann perimeter in a group of 13 children between the ages of 4 and 14 years with congenital glaucoma and 10 age-ma... | null | 0.652 | 55 | Medicine; Pediatrics, Perinatology and Child Health; Ophthalmology | Medicine | 2,000 |
11,020,057 | Characteristics of pediatric urolithiasis in south-east Anatolia. | International journal of urology : official journal of the Japanese Urological Association | Int J Urol | 7 | 9 | 10.1046/j.1442-2042.2000.00207.x | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] Urolithiasis is endemic in Turkey and characteristics of urolithiasis vary in different regions of the world. The aim of the present study was to evaluate the etiological and clinical characteristics and course of pediatric urolithiasis in south-east Turkey. [METHODS] The study population consisted of 81 c... | null | 0.513 | 83 | Urology | Medicine | 2,000 |
11,018,691 | Erythrocyte protoporphyrins in hepatitis C viral infection. | Clinical biochemistry | Clin Biochem | 33 | 5 | 10.1016/s0009-9120(00)00149-1 | eng | 2,000 | 7 | null | null | null | null | [OBJECTIVES] Protoporphyrin is the immediate precursor of the heme molecule. Due to a spillover from hemaotopoietic tissue it is regularly found in small amounts in erythrocytes and excreted into the bile. In hereditary erythropoietic protoporphyria excess protoporphyrin accumulates and can cause severe liver damage bo... | null | 0.568 | 130 | Medicine; Clinical Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,018,499 | Determinants of physiologic tremor in a large normal population. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | Clin Neurophysiol | 111 | 10 | 10.1016/s1388-2457(00)00384-9 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] It has been well established that peripheral mechanical resonant factors as well as central mechanisms may play a role in the generation of physiological tremor (PT). Furthermore it has been postulated that subject's attributes like age and sex might influence PT. The present study was designed to quantify... | null | 0.606 | 230 | Neurology; Neurology; Physiology; Sensory Systems | Medicine; Neuroscience | 2,000 |
11,018,490 | Excitability recovery curve of the sympathetic skin response in healthy volunteers and patients with palmar hyperhidrosis. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | Clin Neurophysiol | 111 | 10 | 10.1016/s1388-2457(00)00394-1 | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] Patients with primary palmar hyperhidrosis (PPH) might exhibit hyperexcitability of the reflex circuits involved in sweating. We hypothesized that this hyperexcitability could become evident in the study of the excitability recovery curve of the sympathetic sudomotor skin response (SSR). [METHODS] In 10 pa... | null | 0.606 | 230 | Neurology; Neurology; Physiology; Sensory Systems | Medicine; Neuroscience | 2,000 |
11,018,093 | Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines. | Journal of the National Cancer Institute | J Natl Cancer Inst | 92 | 19 | 10.1093/jnci/92.19.1573 | eng | 2,000 | 10 | 4 | null | null | null | [BACKGROUND] HER2 is a membrane receptor whose overexpression is strongly associated with poor prognosis in breast carcinomas. Inhibition of HER2 activity can reduce tumor growth, which led to the development of Herceptin, an anti-HER2 monoclonal antibody (MAb) that is already in clinical use. However, the objective re... | null | 3.237 | 394 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,017,929 | Transferrin polymorphism influences iron status in blacks. | Clinical chemistry | Clin Chem | 46 | 10 | null | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] Genetic variants of human transferrin (TF) have been described, but little is known about their functional differences. We studied iron status according to TF phenotype in a healthy Zimbabwean population and in subjects at risk of African iron overload. [METHODS] The study population consisted of 483 nondr... | null | 1.222 | 248 | Biochemistry; Clinical Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,016,765 | Differentiation of vascular birthmarks by MR imaging. An investigation of hemangiomas, venous and lymphatic malformations. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 41 | 5 | 10.1080/028418500127345677 | eng | 2,000 | 9 | null | null | null | null | [PURPOSE] To evaluate the use of MR imaging using standard sequences in the differentiation of common vascular birthmarks of soft tissues in childhood. [MATERIAL AND METHODS] Forty-three lesions in 37 children (median age 33 months) with hemangiomas (n=25), venous (n=8) and lymphatic (n=10) malformations were retrospec... | null | 0.681 | 82 | Medicine; Radiology, Nuclear Medicine and Imaging; Radiological and Ultrasound Technology | Health Professions; Medicine | 2,000 |
11,016,752 | Quality of life after adjuvant chemotherapy for breast cancer. | Breast cancer research and treatment | Breast Cancer Res Treat | 62 | 2 | 10.1023/a:1006401914682 | eng | 2,000 | 7 | null | null | null | null | [PURPOSE] To evaluate the quality of life of breast cancer patients previously treated with adjuvant chemotherapy. [METHOD] Registry data were used to recruit a sample of breast cancer patients (N = 61; mean age = 51.6 years) with no current evidence of disease who had completed adjuvant chemotherapy between 3 and 36 m... | null | 1.151 | 184 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,016,720 | Sentinel node biopsy for malignant melanoma: analysis of a four-year experience. | Tumori | Tumori | 86 | 4 | 10.1177/030089160008600421 | eng | 2,000 | null | null | null | null | null | [AIMS AND BACKGROUND] Sentinel node (SN) biopsy has been introduced to solve the controversy concerning the effectiveness of prophylactic lymphadenectomy in intermediate thickness melanoma. The aim of this study was to evaluate the rate of metastases, the technical details of the procedure, and the main reasons of fail... | null | 0.243 | 59 | Medicine; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
11,016,386 | Hemodynamic effects of carbon dioxide insufflation during endoscopic vein harvesting. | The Annals of thoracic surgery | Ann Thorac Surg | 70 | 3 | 10.1016/s0003-4975(00)01780-x | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] A prospective study was performed assessing the hemodynamic effects of carbon dioxide (CO2) insufflation during endoscopic vein harvesting (EVH) using the Guidant Vasoview Uniport system. [METHODS] Five hemodynamic and respiratory parameters (end-tidal carbon dioxide, arterial partial pressure of carbon di... | null | 1.356 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
11,016,316 | Right Y-graft, a new surgical technique using mammary arteries for total myocardial revascularization. | The Annals of thoracic surgery | Ann Thorac Surg | 70 | 3 | 10.1016/s0003-4975(00)01500-9 | eng | 2,000 | 9 | null | null | null | null | [BACKGROUND] We report a new technique that consists of a right Y-graft using only skeletonized internal mammary arteries (IMA) for total arterial myocardial revascularization. [METHODS] This technique consists of anastomosing the in situ left IMA (LIMA) and right IMA (RIMA) to the left anterior descending and obtuse m... | null | 1.356 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,000 |
11,015,250 | Low plasma thiamine levels in elder patients admitted through the emergency department. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | Acad Emerg Med | 7 | 10 | 10.1111/j.1553-2712.2000.tb01268.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] To determine the prevalence of thiamine deficiency in a high-risk group of elder emergency department (ED) patients who reside in nursing homes and need admission to the hospital, and to determine the effect of patients' diets on this prevalence. [METHODS] This was an observational pilot study of 75 consec... | null | 0.851 | 148 | Emergency Medicine; Medicine | Medicine | 2,000 |
11,015,240 | The efficacy of nebulized racemic epinephrine in children with acute asthma: a randomized, double-blind trial. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | Acad Emerg Med | 7 | 10 | 10.1111/j.1553-2712.2000.tb01258.x | eng | 2,000 | 10 | null | null | null | null | [OBJECTIVES] Recent work in bronchiolitis has demonstrated a significant clinical improvement in children treated with epinephrine over nebulized salbutamol. The objective of this study was to determine whether nebulized epinephrine, as compared with nebulized salbutamol, causes a greater clinical improvement in childr... | null | 0.851 | 148 | Emergency Medicine; Medicine | Medicine | 2,000 |
11,015,102 | Dynamic helical computed tomography scan accurately detects hemorrhage in patients with pelvic fracture. | Surgery | Surgery | 128 | 4 | 10.1067/msy.2000.108219 | eng | 2,000 | 10 | null | null | null | null | [BACKGROUND] The purpose of this study was to evaluate the use of dynamic helical computed tomography (CT) scan for screening patients with pelvic fractures and hemorrhage requiring angiographic embolization for control of bleeding. [METHODS] Patients admitted to the trauma service with pelvic fractures were identified... | null | null | null | null | null | null |
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