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Cancer cells reprogram their metabolism to fuel anabolic processes required for their proliferation and survival. One way by which cancer cells reprogram metabolism is by hijacking the evolutionarily conserved metabolic function of the PI3K/Akt/mTORC1 signaling pathway. Another way is by markedly elevating the expression of the hexokinase isoform, HK2, which catalyzes the first committed step in glucose metabolism. The long-term goal of this grant application is to overcome challenges in targeting cancer metabolism and Akt for cancer therapy. Although cancer cells can be selectively detected because of their high glucose metabolism (FDG-PET scan), exploiting this property for selective targeting is challenging because interference with glucose metabolism could have adverse consequences. We overcame this roadblock by showing that hexokinase 2, which catalyzes the first committed step in glycolysis, and is selectively expressed in cancer cells, can be systemically deleted in mice without any adverse consequences. The proposal is based on findings made in my laboratory at the cellular and organismal levels, and address the following paradigm shifts: (i) Germ-line deletion of hexokinase 2, which is markedly elevated in cancer cells, is embryonic lethal. However, we found that its systemic deletion in adult mice is well tolerated, and therapeutic in several mouse models of cancer. This grant application will specifically address the role of hexokinase 2 in metastasis. We will investigate the role of hexokinase 2 in EMT and metastasis through a novel mechanism. (ii) Akt is perhaps the most frequently activated oncoprotein in human cancer. However, we found that, paradoxically, hepatic deletion of Akt1 and Akt2 in mice induces liver injury, inflammation, and early onset of hepatocellular carcinoma. We will determine how the HCC cells survive and proliferate in the absence of Akt. (iii) We found that systemic deletion of Akt1 and Akt2 in adult mice elicits rapid mortality, and that Akt2 deficiency in mice could be pro-tumorigenic and increased metastasis of chemically- induced HCC, possibly because of hyperinsulinemia. Therefore, we launched a comprehensive approach in which Akt1 or Akt2 or both can be conditionally deleted either in a cell autonomous manner or systemically, after tumor onset, to follow tumor growth and metastasis. Our findings showed marked and unexpected differences between cell autonomous versus systemic deletions of Akt isoforms with respect to tumor initiation and progression. (iv) The inhibition of AMPK is considered pro-tumorigenic. Paradoxically, we found that AMPK activation is required for cell survival during solid tumor formation and possibly metastasis. We will delineate the role of AMPK during metastasis in human cells and mouse models of breast and prostate cancer. We anticipate that the proposed studies will uncover new mechanisms of tumorigenesis associated with cancer metabolism, yield strategies that exploit cancer metabolism for cancer therapy, and uncover vulnerabilities of cancers displaying hyperactivation of PI3K/Akt signaling.

All-trans-retinoic acid (ATRA) and its stereoisomer, 9-cis-retinoic acid (9-cis-RA), are two active metabolites of vitamin A which are known to regulate a broad range of biological processes, including vertebrate development, growth, proliferation and cell differentiation. Retinoids are understood to induce cell differentiation by binding to distinct families of ligand-activated nuclear receptors (RARs) and retinoid X receptors (RXRs). Naturally occurring retinoids, including ATRA, 9-cis-RA (9CRA) and 13-cis-retinoic acid (13CRA), can be described as chromophores since they selectively absorb light. Such molecules are essentially composed of three structurally distinct regions: a hydrophobic end, a polyene linker and an acidic group. The polyene linker in naturally occurring retinoids is highly conjugated and it is this region that gives it the ability to absorb light (at a frequency of 300-400 nm depending on the solvent). It is due to this feature that these molecules are particularly susceptible to photoisomerisation and can degrade into a mixture of different retinoic acid isomers. The resulting concentration of retinoid levels has also been shown to decrease markedly over time in culture and this could be a consequence of both their degradation and metabolism. Moreover, retinoids such as ATRA are temperature sensitive and are known to oxidise readily. Isomerisation of ATRA is understood to be an important part of its metabolic pathway because the resulting isomers have different mechanisms of action. This is an important point that is all too often over-looked by users of ATRA in the cell culture laboratory. It has been reported that the isomers of ATRA differentially affect the ability of mammalian stem cells to differentiate along alternative lineages and stated that extreme care should be taken to protect retinoic acids from isomerisation in such experiments (Murayama et al J. Nutr. Sci. Vitaminol 43(167) 1977. This is particularly relevant when the cellular response is determined by the concentration(s) of the isomer(s) present in solution. For example, the induction of the differentiation of pluripotent stem cells using retinoids is quite often variable, resulting in the formation of heterogeneous cultures of cells composed of different proportions of alternative cell types. To reduce such variability in differentiation response and improve reproducibility, it is essential that whatever is used to induce cell differentiation is in the same form and concentration every time it is used. Currently, this cannot be guaranteed when using reagents such as ATRA and its stereoisomers, all of which are light and heat sensitive and are prone to undergo isomerisation under sample preparation conditions, under storage of stock solution conditions and in culture conditions. It is because the different isomers have diverse effects on cells that some attempts have been made to control ATRA's sensitivity and tendency to isomerise. For example, a number of additives preventing cis-trans interconversions or oxidation of retinoic acids have been evaluated, including bovine serum albumin (BSA), fibrogen, lysozyme, phosphatidylcholine N-ethylmaleimide and vitamin C (Chen et al. J. Am. Chem. Soc. 126 (410) 1995; Wang et al. J Chromatogr 796, 283, 2003). However, the addition of such molecules to cell culture media is not desirable; for example, the use of BSA would not be possible in serum free culture media. There is a need for improved alternatives to ATRA that do not suffer from the aforementioned stability problems and which can readily be used in cell culture applications.

This invention relates generally to the providing or supplying of inflation gas. More particularly, the invention relates to assemblies for providing or supplying an inflation gas such as may be desired for certain inflatable passive restraint systems for use in vehicles for restraining the movement of an occupant in the event of a vehicular collision as well as methods of forming or making such inflator assemblies. It is well known to protect a vehicle occupant by means of safety restraint systems which self-actuate from an undeployed to a deployed state without the need for intervention by the operator, i.e., “passive restraint systems.” Such systems commonly contain or include an inflatable vehicle occupant restraint or element, such as in the form of a cushion or bag, commonly referred to as an “airbag cushion.” In practice, such airbag cushions are typically designed to inflate or expand with gas when the vehicle encounters a sudden deceleration, such as in the event of a collision. Such airbag cushions may desirably deploy into one or more locations within the vehicle between the occupant and certain parts of the vehicle interior, such as the doors, steering wheel, instrument panel or the like, to prevent or avoid the occupant from forcibly striking such parts of the vehicle interior. For example, typical or customary vehicular airbag cushion installation locations have included in the steering wheel, in the dashboard on the passenger side of a car, along the roof line of a vehicle such as above a vehicle door, and in the vehicle seat such as in the case of a seat-mounted airbag cushion. Other airbag cushions such as in the form of knee bolsters and overhead airbags also operate to protect other or particular various parts of the body from collision. In addition to one or more airbag cushions, inflatable passive restraint system installations also typically include a gas generator, also commonly referred to as an “inflator.” Upon actuation, such an inflator device desirably serves to provide an inflation fluid, typically in the form of a gas, used to inflate an associated airbag cushion. Various types or forms of inflator devices have been disclosed in the art for use in inflating an inflatable restraint system airbag cushion. One particularly common type or form of inflator device used in inflatable passive restraint systems is commonly referred to as a pyrotechnic inflator. In such inflator devices, gas used in the inflation of an associated inflatable element is derived from the combustion of a pyrotechnic gas generating material. Typically, pyrotechnic inflators include a pressure vessel housing so as to be able to withstand the 10 MPa to 30 MPa internal pressures created during combustion of the pyrotechnic gas generating material contained within the inflator. In practice, such pressure vessels are commonly made by welding together two or more metal, e.g., steel or aluminum, components after the loading therein of the inflator internal contents, such as the pyrotechnic gas generating material, for example. The automotive industry, however, continues to seek inflatable restraint systems that are smaller, lighter, and less expensive to manufacture. As industry constraints regarding factors such as the weight and size of vehicle components continue to evolve, corresponding changes to associated inflatable restraint systems are desired and required in order to better satisfy such constraints.

Many swimmers use swimming caps to cover their heads during swimming. Swimming caps generally cover the upper portion of the swimmer's ears and contain the swimmer's hair during swimming. In competitive swimming where winning margins are often measured in hundredths of a second, a swim cap may be particularly important for reducing the hydrodynamic drag on the swimmer. A conventional swim cap covers the crown of a swimmer's head, a portion of the swimmer's forehead and the ears, and the upper portion of the nape of the neck. The wearer's hair is generally tucked inside the cap during use. Conventional swim caps are typically generally hemispherical in shape and are made from a relatively thin, pliant, stretchable, and resilient material, such as a manmade fabric (e.g., spandex), silicone, or latex. Silicone and latex are convenient materials for swim caps due to their relative toughness, flexibility, and easy manufacturability. The pliability of the conventional swim cap is particularly important when the swimmer is engaging in strokes requiring a high degree of arch in the back and neck, such as the butterfly stroke, so that the swim cap does not interfere when the swimmer's neck is arched back. A disadvantage of conventional swim caps, however, is that the upper portion of the swim cap tends to deform during use, forming transverse wrinkles, particularly over the crown of the swimmer's head. These transverse wrinkles result from a variety of factors, including the highly flexible and stretchable materials used to form the swim cap, the swimmer's hair enclosed by the swim cap, the motion of the swimmer's head and neck, and hydrodynamic and other forces acting on the swim cap during entry into the water and swimming. The transverse wrinkling reduces the efficiency of the swimmer by increasing the hydrodynamic drag as the water flows about the swim cap. In addition, during use a conventional swim cap typically covers only the upper portion of the swimmer's ears, leaving a portion of the ears in the flow stream. It would therefore be beneficial to provide a swim cap that adequately covers portions of the swimmer's head and hair, including all of the swimmer's ears, but that does not tend to form wrinkles or otherwise deform to reduce the efficiency of the swimmer in the water.

"For God's sake, look at the state of my curtain." "Look at you." "If I've told you once, I've told you umpteen times." "Keep your trousers tucked in your boots." "Ryan Quinn!" "Are you listening to me?" "Come here." " Ma, can I go out and play?" " You can go out after." "Ma, leave it." "I'll do it." "I look like a spaz with them tucked in." "You won't say that when you trip and fall on your backside." "I look stupid." "You keep 'em tucked in." "Is your foot in?" " Yes." "I'll do it myself." "Ma, can I go out and play?" " No, you can't." " Ma, where are you going?" "Ma, can I go out and play, please?" "You're going to see your dad." "Don't you want to see your dad?" "James, what are you up to?" "What are you doing?" "You fucking bastard!" "Did you shit yourself?" "I got you one there, huh?" "I think this is what I'm looking for." " Hi, how you doing?" " Fine." "How are you?" " Just going to Susan's." " Say hello for me." "See you later." "I thought it was you." "To the little man." "Get the fuck away from there!" "Hey, beat it!" "This is me." "You're not going to let me /walk up here by myself." "Look, why don't you come up /to my place for a little coffee?" "George, what you need /is a good woman to look after you." "George!" "Where have you been?" "Go back to sleep." "Watch where you're going!" "A little mouse!" "Don't be touching it, darling." "No, no, no." "Give me your hand." "Don't, please." "You can't touch it." "It's vermin." " It's just a little mouse." "Well, these conditions /speak for themselves." "You can't possibly deny" "that there is a very considerable /health risk under which" "many of the good people /of Glasgow are at present living." "There's a risk in the form /of decomposition of this material," "a risk of fire," "a risk of it being spread by rats," "which are notorious vectors /of disease." "Remember Pete Connelly?" "He waited months before he heard anything." "You've told me already." "Well, they ended up with a great house, didn't they?" "They were going to throw this stuff out at work." "What's that for?" "It's brand-new." "Hasn't even been opened." "What color is it?" "It's a kind of pastel shade." "You've got to be joking." "It's gray!" " It's pale blue." " Your ass it is." "Look at it in the light." "It's pale blue." "Definitely." " You're not putting that up in here." " Why not?" "It's good-quality paint." " It's bloody horrible!" "Look, give this place a couple of coats, cheer it up a little bit, it's going to look beautiful." "What's the point?" "We're moving." "Yeah, maybe." "There's tea in the pot if you want some." "All right, I'm off." "It's good-quality paint." "James, don't you go near that canal." "Do you hear me?" "What are you staring at, you little pervert?" " That's my ma's." " So?" "What's it got to do with you?" "Do you want a photo?" " Of you?" "Stop making a mess of that table." "Shut up." "Hey, gorgeous!" "Where are you going?" "Don't you have a pal or something?" "Where are you going?" "Nowhere." "Make yourself useful." "Get me a can of beer from the fridge." "What?" "Go on, do what I tell you." "Move." "Yes!" "You beauty!" "Go on, son!" "Beautiful, Celtic, beautiful!" "I'm telling my dad on you." "My head!" " Big girls don't cry." "Go away." " You gonna tell my da?" " Yes, I'm telling." "And I'll tell him you drank his beer as well." "Anne Marie, shut up!" "Okay, I won't tell." " So you're not gonna tell my da?" " No, I won't tell." "Where's my beer?" "Dad?" "Where were you?" "You gonna watch football?" "It's an old firm game." " I don't like football." " I like football, Dad." "Can I watch it?" "You come over here and watch it with me." "I've got it." "Over here!" "Where's the little mouse?" "Remember that little mouse you put down the toilet?" "The little mouse." "It's gone out to sea, darling." "The seaside?" "Yes." "It went for a swim." "Da, James hurt me." "He drank your beer as well." "Did he now?" "I'll see to that later." "Now let me watch." "Go on, son." "Jump for it!" " You killed my mouse, Dad." "Yes, yes!" "Goal!" "Attack!" "Give them back, you bastard." " Say pretty please." " Pretty please." " Pretty please with a cherry on top." " Pretty please with a cherry on top." "What will you give me if I give you them?" " Anything." " No." "Fuck off." " The stupid cow can't see a thing." " Have you lost your panties as well?" "Just give me them back." "See you later, darling." "You bastard!" "Fucking cow." " Asshole!" " Fuckin' bitch!" "Can you see my glasses in there?" "Can you?" " No." " Are you sure?" " Yes." " Come and sit over here." " What?" " Sit here." " What's your name?" " James." " You want a drag?" " No." "I'll kill that bastard Matt Monroe." "That canal gives me the creeps." "Did you know that boy who drowned down here?" "Ryan Quinn?" "You wanna touch it?" "See you later, James." " It's heavy." " Help me get it on." "Don't tilt it too much." "Have you got it?" " Yes." "Hurry up." "Hold on a minute." "Okay, push it in." "Lift it up." "What did you let go for?" " It's your fault." " What are you talking about?" " It's all your fault!" "You want to calm down?" "What's the matter with you?" "You killed my boy." "What are you fucking talking about?" "That was my boy as well." "I loved him just as much as you, and you know it." "You killed him." "You weren't there!" "Come on, get a grip on yourself." "Please." "Get away from me, you bastard." "I hate you!" "Get away!" "I can't deal with you anymore." "Every time I come near you, we argue." "He left us." "He left my boy." "I couldn't watch him myself." "I hate him." "He killed my boy." "Where is James going?" "James, get my packages." "Leaving them lying in the middle of the street." "Hurry up." " James, come here, son." " Where are you going?" " I was gonna take the packages up." " Just do what you're told." "Would you give me a little hug?" "He's the double of my Ryan, isn't he?" "The same eyes." "Yes." "Maybe a little." "Will you do me a little favor?" "Will you go up to Ryan's room for me and get the little box on Ryan's bed?" "Will you do that for me?" "Go on, James." "It's all right." "Oh, fuck." "They look great." " They're hurting me." " Shut up, you." "What do you say?" "Say thanks to Mrs. Quinn." " They're too small." "Thanks." "James, look what I've got." "Ah, it's lovely." "What's its name?" " Suzy." "She's a she." " It's nice." "I've got budgies and gerbils in the house." "On my birthday I'm getting rats, tigers, bears, and mouse-eating snakes." "That's good." "When I'm older, I'm going to have the biggest zoo in the world." "Look." "I'm a member of the RSPCA." "That's good, man." " What are you looking for?" " Nothing." "Wow, look at all the little tadpoles in there." " Have you ever seen a perch?" " A peach?" "A perch." "It's about that size, with spiky, jagged fins." "I saw a guy catch one the other day." " Was it big?" "About that size." " You want to catch one?" " It's not that easy, Kenny." "I've got a net in the house." "It would pull you under." " I'm a great swimmer." " Another time, Kenny." "See you later." "James, what am I?" "Are you a bird?" "No, I'm an ostrich." "An ostrich can't fly." "See you later, Kenny." "James, are you coming to my zoo tomorrow?" " Maybe." "Bye." " See you later." "Is your mommy home, sweetheart?" "She just went out to see my auntie at the hospital." "Because I thought I saw her coming up the road there." "She came up and then she went back out." "I see." "Will you give her this?" "Your mom's never in, is she?" "Here, give her this from me." "Tell her the rent is due." "Has he gone away?" "You could get 50 pence for this." "A nice one there." "The smell in this place!" "What's that?" "Somebody's tossed out a perfectly good dog." " The smell of it!" " It's full of maggots." " Fancy a swim?" " Fuck off." " Fancy a Ryan Quinn?" " Fuck off." "You first, mate." "Are you a good swimmer?" "In you go." " Piss off." " What?" "Hey, leave him alone." "Don't do that to the little guy." " You shit yourself." " Just joking." "Hey, Stephen!" "All right!" "Big man." "How are you doing?" "We're off to Margaret Anne's." "Keep a look out the window in case her ma comes." " "All right, Margaret Anne, guess who. " - "Billy? "" "Try harder." "Who is it, Margaret Anne?" "Stephen." "Okay, I don't know, but you better /get my glasses back, you prick." "Who is it, Margaret Anne?" "It's you, Tommy." "Just fuck off." " "Not bad, girl." "One out of four. " - "Leave me alone. "" "Your breath stinks." "Piss off." "Piss off." "Don't you want a shot, man?" " Go on." " Come on, on you go." "Hurry up." "Go for it." "Go for it." "Go on." "Scared of the bird?" "Whip it out." " We've been there, done that." " Got the T-shirt." "Hey, man, you okay?" "What's it like down there?" "He boldly went where no man's gone before." "Call an ambulance for that guy." "Feather duster." "Push the cobwebs away." " What was that?" " He stuck his two fingers up at us." "Hi, Lisa." "Hi, Leanne." "Margaret, is it all right if I leave her here?" "My ma will be back soon." "Lisa, don't play in the rubbish." "Where are you going?" "Piss off." "I'm telling my ma on you." "I can do what I like." "It's a free country." "There's no way you're getting on this bus with me." "Go home." "Beat it." " Have you got a boyfriend?" " It's none of your business." "Look at the state of your knees." "They're pure black." "No, they're not." "Look, go home." "You're not getting on this bus with me." " Just tell me where you're going." " No, I'm not telling you nothing." " Can I have a ten pence, please?" " Where are you going?" " Can I have a ten pence, please?" " Where are you going, son?" "Here." "Just go on." "Go on." "Okay, son, that's as far as I go." "This is the end of my line." "Are you getting off or what?" " You know I love you, don't you?" " Oh, go away." "Come here, gorgeous." "I'm always gorgeous when you're half drunk." "Your ma..." "is one in a million." "Da, shut up." "I'm trying to watch this." "Your ma is one in a million." "Look at him." "Anne, have you seen my cigarettes?" "Ow, it's stinging!" "It's nowhere near your eyes." "Get up." "They're not here." " "Scottish League Division Two, "" " I was watching that." "Stirling Albion 20, Selkirk 0." "You jerk." "What?" "Come here, you." "You've been scratching and all." "No, I haven't." " Your head's crawling." " No, it's not." "James, sit." "Where are my cigarettes?" "Has anyone seen my cigarettes?" "If you'd open your eyes, you might find them." "They're over there." "I looked there." "There's your wages, sweetheart." "You want me to leave a couple of cigarettes for you?" "No, that's all right." "I've got some." "Okay, see you later." "James, take this trash down." "You take it down!" "I got them from you, you little cow." "Shut up!" "Ma, he was scratching before me." "Take her out now and get her ready, will you?" "Ma, have you heard anything about the new house yet?" "No, sweetie, we're still waiting." "Keep your head down." " Can I see it?" " Stay still." "What do they look like?" "I can't see anything." " Look." "Is that it?" "James, you're gonna catch lung cancer." " Is that right, Kenny?" " I'm not allowed to play down there." "It's an envir... an enviro..." "A really mental health hazard." "What?" "Guess what." " What?" " It's my birthday today." "Happy birthday." "Want to see my present?" "Two minutes." "Are you still here?" " Yeah." "Are you all right in there, Snowball?" "Happy birthday, Kenny." " "Who's your pal, James? " - "Look, it's animal boy. "" " What's that you've got?" " Stop it." " I'm not doing anything." " Stop it." " Look, it's a rat." " It's not a rat." " What's its name, Kenny?" " Snowball." " Ah, that's lovely." " Let's see it out." "No." "OnlyJames can see it." "Let me see it." "It's lovely." " Let me see it." " No." "Come on, you're one of the boys." "Am I, James?" "Yeah, so is James." "He's one of us." "Okay, then, but only for a minute." "The little bastard bit me." "Give me my mouse back." "The fucking thing cut my finger." "Give it back!" "Give me my fucking mouse back!" "Move." "I want it back!" "You're going to kill it." "Throw it on the ground." "It can fly, Kenny." "Let it fly toJames." "Go on." " All right, James!" "My mouse can fly." " Where's it gonna fly to?" " Go on, James." "Fucking kill it." " Where will it fly to, James?" "Just fling it at the wall." " The moon." " That's sad." "My mouse is going to the moon?" "You better put it back in its cage." "It's done enough flying today." "My ma's gonna slap you for this." "Your mother only wears panties to keep her ankles warm." " "Is that a friend of yours, James? " - "You going to the moon with him? "" " "Look, James. " - "He's a fuckin'psycho. "" ""I'm going to the moon. "" "Look, everybody." "Bye-bye, Snowball." "Hi, James." "Hi, Kenny." "What are you doing?" " What?" " What are you doing?" " I'm gonna catch a perch." " How are you gonna do that?" " I'll show you." "You see this bread?" "I'm going to throw it in like that." "When they come up, I'm going to do this and catch it." "I'll catch one, James." "Watch this." "I've got it, I've got it!" " Do some more." "See that, man?" " What was that, Kenny?" " They're bitin'." " Aren't there any down there?" " Don't know." "Must be." " You want a hand?" " No, James." "I want to do it all myself." "Okay." "I'm gonna go, Kenny." "See you later." "Is he stupid or something?" "He's all right." "I've got one." "Oh, it got away." "Ow, you're hurting me." "You wanna see 'em?" "I can't see anything." "There's the little beast." "See?" "You need your glasses back." "Hang on." "I'll find another one." "A bigger one." "I've got it." "See it?" "Yes, I think so." "The big beast." "You're done." "Did you kill them all?" "I think so." "You need to go wash it now." "George!" "George, you have to help me." "It's my boy... he's in the canal!" "You've got to wet your hair first." "Fifty-seven!" "I can get up to 7 0 if I count faster." " Where's the soap?" " I don't know." "I need to pee." "Although neither side /is willing to say so openly," "it's clear the threat to bring in troops /made the strike leaders back down." "Clearing up all this mess will mean /thousands of pounds" "in bonuses and overtime /for the refuse collectors," "compensating them for the nine weeks /they've been on strike." "The threat of someone else /doing the work" "and the fact they'd lose /all the extra money" "produced an abrupt /change of heart." "Your da's a hero." " "Is your mother or father in? " - "My da's in, but he's sleeping. "" " "We're from the council." "Can we come in? " - "Is it about our new house? "" "Come on in." "Da." "It's the new house people." "Wake up." " Fuck off." " It's the new house people." " What?" "Who the fuck are you?" "I'm Miss McDonald." "This is Mr. Mohan." "We're from the council." "We've come to inspect the condition of your property and assess your standard of living." "Have we caught you at a bad time?" "We just want to look around." " Mrs. Fowler's boy was in the canal." "I had to go in the canal, and I can't even swim." "I had to go through the rubbish out back." "Have you seen out there?" "It's a fucking disgrace." "I see it's a three-bedroom property you're looking for, Mr. Gillespie." "That's right." "Are we getting a big house with a bath, a toilet and a field?" "Are we, Da?" "You'd better come back when the wife's here." "We've got all the information we need." "Thanks very much, Mr. Gillespie." "Bye-bye now." "Sorry about the mess." "Come here, you." "Can't you fucking do anything right?" "What did you let them in for?" " 'Cause I thought that..." " 'Cause you thought." "Are we still getting the new house?" "If we don't, it's your fucking fault." "Now get out of my sight." "Would you hold still a minute?" "What's the matter with you?" "I'm itchy." "Are you about finished?" "I think you caught something in that canal." "All right, you're all done." "Margaret says the council inspectors were up to see her house today." "They didn't come here, did they?" " Who?" "This place was a mess." "Dad, here." "Mr. Mullen never took the money for it." "He didn't?" " Tell you what:" "You keep it, sweetie." " Really?" "Thanks, Da." "He told me to tell you you're a hero." " Did he?" "Look at the face on you." "Here's your shoes, Daddy." "That's brilliant." "Can I have 50 pence?" "That's Mom's!" "Where does that boy go?" "Ladies and gentlemen, /boys and girls," "it's a great pleasure for me /as Lord Provost" ""to welcome you here"..." "Check out that guy's sideburns." "James, do you think Snowball's on the moon yet?" "You be quiet." "I don't want to hear another word about that mouse." "Now shut up." " Even the McKays are moving soon." " Yes, I heard, sweetie." " When are we going to be moving?" " We'll hear soon." "You always say that." "I will now hand out the certificates and the medals as awards for your acts of bravery." "Thank you very much, ladies and gentlemen." "As I call your name, will you please come forward?" "Thanks, George." "Don't know what I would have done." "I can't thank you enough." "What have you got to say to Mr. Gillespie, Kenny?" "We sent Snowball to the moon." "Didn't we, James?" "What did I tell you to say?" "Look at the man when you're speaking!" "Thanks for saving my wife..." "I mean life." " My da's a hero." " That's right, sweetheart." "Look, there he is up there." "See him?" " Alan McCallen." " George Gillespie." "Da, it's lovely." "Can I keep it?" "I'm going for a quick drink, meeting the boys at the pub." "Don't be too long." "See you later, sweetie." "Ma, remember:" "Put Tom Jones on." "Ma, I asked you to put Tom Jones on." "You weren't listening." "I told you to put Tom Jones on." "You guys wouldn't know a good tune if it came up and bit you." " Put Tom Jones on!" " Stop screaming in my ear." "Tom Jones is shit, Anne Marie." "You're a big shit." "Hey, you two, that's enough of that language in my house." " He said it first." " You hear me, young lady?" " Da swears all the time." " Okay, who's dancing?" "Come on, who's gonna dance?" "I'll dance by myself." "Me and your da were the best jivers at the Lindella." "She's mad." "Is that right?" "Bet you couldn't do it." "Are you dancing?" "You're supposed to say, "Are you asking?" Are you dancing?" " No way." " Come on, James." "One dance for your Ma." "James can't jive." "James can't jive." "Watch this move." "James can jive." "Let's try a double." " James can't jive." " Yes, he can." "James is a good jiver." "I'll dance with you, Ma." "One drink, one little drink." "That's all." "Then you can go home." "You're a lovely woman, but I need to go." "I don't have any money." "Come on." "I've got to go." "Buy yourself a drink, okay?" "You're a lovely woman." "See you later, darling." "Look after yourself." "You too." "Bye." "Mister, can you hold my cat for me so I can go to the ice cream van?" "Sure I can." "Be careful crossing the street." " Yes, dear?" " Can I get one of these?" "Where'd you get the cat, you pussy?" "Fuck off, all of you." "Who do you think you're talking to?" "Try them on." "I don't want to." "I bought them for you, you ungrateful little bastard." "Now get 'em on." "Look at 'em." "They're too big." "Let me see." "I don't fuckin' like football!" "I thought I heard a noise." "What are you doing up here, son?" "Who are you looking for?" "Don't you have a tongue in your head?" "Oh, my God, they're getting younger and younger." "Another one." "Shit." "There's your ma." "Don't worry, she won't come in." "Just turn the light out." "I'm freezing." "Aren't you coming in?" "James, do you love me?" "Yes." "Come on, let's go." "Don't forget that mask." "Get those masks on!" "Scabs!" "You're nothing but a bunch of scabs." "Every last one of you." " "Shut your face. "" "It's about time /these bags were cleared." "You mind your own business, /you old cow!" "Hey, come on." "Beat it!" "James!" "Look!" " Can I get up?" " No, we're too busy." "James, look." "I killed it." "I thought you were a member of the RSPCA." "My ma says they're verm... verm..." "They're pests." "You're ma's looking for you." " Is she?" "Yes." "Look at the moon." "Hello, Snowball." "Snowball's dead, Kenny." "You killed him." "Calm down, for fuck's sake." "Go for it." "Poor cow, poor cow, poor cow, poor cow." "Come on, it's my turn." "Remember, be nice to him." "I'm not your pal anymore." "Fuck off, fuck off." " Fucking spastic!" " I saw you, I saw you, I saw you." "You killed Ryan Quinn." "You killed him." "Where have you been?"

German Patent Application Nos. DE 100 19 416 A1, DE 100 19 417 A1, and DE 100 19 418 A1 describe general concepts for rollover sensing using methods and devices based on the analysis of a yaw rate sensor and two acceleration sensors which are integrated in the central airbag control unit. The yaw rate sensor ascertains, by the gyroscopic principle, the rotation rate about the longitudinal axis of the vehicle; in addition, the acceleration sensors measure the acceleration of the vehicle in the direction of the transverse and vertical axes of the vehicle. The yaw rate is analyzed in the main algorithm. Using the measured values of the acceleration sensors, the type of rollover may be recognized, and these values are also used for plausibility checking. If the yaw rate algorithm detects a rollover, safety measures are activated only if they are enabled by the plausibility check at the same time. A timely deployment decision in the event of a rollover at a high lateral acceleration by taking into account a float angle and a transverse velocity of the vehicle, as well as a vehicle tipping motion, is described in German Patent Application No. DE 101 49 112 A1. However, the float angle and therefrom the lateral velocity as needed for rollover detection are not determinable by conventional methods such as used in vehicle dynamics control, for example, in an angle range greater than 20°. These methods, such as those using a model from tire characteristics and lateral force, for example, are suitable only for angle ranges of less than 10°. The reason for the small validity range is that vehicle dynamics control may no longer be successfully performed at larger float angles. German Patent Application No. DE 102 39 406 A1 describes a device for determining float angles greater than 20° and the lateral velocity for rollover detection. This device divides the vehicle's state into chronologically consecutive phases and determines the float angle and the vehicle's transverse velocity from the vehicle dynamics data differently in the individual phases. The disadvantage here is that the initial float angle for “setting up” the algorithm is a constant parameter, which is a function of the application and of the vehicle.

A measurement device has already been disclosed by German Patent Publication 195 24 634 A1, which includes a plate-shaped sensor element with a dielectric membrane that is inserted into a recess of a sensor support. The sensor element is made of a semiconductor material, e.g. silicon, and is manufactured in a micromechanical construction. The membrane is comprised of a dielectric material, for example silicon nitride or silicon oxide. A measurement resistor and a heating resistor are disposed on the dielectric membrane, which are to a large extent thermally insulated from a silicon frame that encompasses the membrane due to the thin embodiment of the membrane and the low heat conductivity of the dielectric membrane. Between the dielectric membrane and the sensor support, there is a hollow space in the plate-shaped sensor element, which extends from a bottom face adjoining the sensor support to the dielectric membrane and is manufactured, for example, by means of an etching process. The sensor element is fixed in the recess of the sensor support by means of a glue. Since the relatively thin membrane must be protected from excess pressure peaks, a ventilation of the hollow space provided underneath the membrane cannot be omitted. The ventilation of the recess in the measurement sensor or the rear of the membrane, however, must take place so that a flow of the medium is kept away from the rear of the membrane in order to prevent the rear flow from contributing to the measurement signal. In order to prevent the penetration of glue into the hollow space adjoining the membrane, the gluing region does not extend over the entire sensor element, but the sensor element is glued into the recess of the sensor support on only half of its surface and the region of the sensor element which has the electric membrane is disposed freely in the recess. In order to prevent underflow of the membrane, i.e. a flow of the medium to the hollow space embodied underneath the membrane, or to at least counteract this, a flow conduit is provided, which is embodied in the sensor support as a channel-shaped recess and extends around the sensor element. At the same time, the provision is made that the recess embodied in the sensor support is matched to the dimensions of the sensor element so that only a small gap respectively remains between the lateral boundary of the sensor element and the lateral boundary of the recess in the sensor support, which permits only a throttled flow of the medium to the hollow space disposed underneath the dielectric membrane. However, it is disadvantageous in this embodiment that the sensor element must be aligned with high precision in regard to the recess of the sensor support during mounting in order to produce the extremely narrow gap. But this task cannot always be reliably fulfilled for tolerance reasons and due to manufacturing variations so that not insignificant losses in efficiency occur during manufacture. A measurement device can be inferred from German Patent Publication 42 19 454 A1, in which a sensor element with a dielectric membrane is inserted into the recess of a cooling body. The cooling body has a ventilation bore between the cooling ribs in order to assure the ventilation of the rear of the membrane.

NEW DELHI: Congress on Saturday said that institutions have weakened under BJP government as judiciary was not intervening promptly on important matters involving citizens’ rights such as Article 370 , leading to anxiety among citizens.It said that on the issue of Article 370, the Supreme Court has constituted a constitutional bench but has not started the hearing.Addressing a press conference, AICC spokesman Anand Sharma said, “There has been institutional subversion and the institutions which I expected to administer and deliver justice to uphold India’s constitutional democracy and fundamental rights of citizens have been weakened. We have expected throughout that the judiciary of this country, being the custodian of the statute, shall protect its foundational values and citizens’ fundamental rights. There are concerns that timely intervention and delivery is not taking place.”The former Union minister and deputy leader of opposition in Rajya Sabha said, “When serious constitutional matters come up, those should be taken up promptly. You cannot delay issues pertaining to the Constitution by months. We hope that will not happen and the judiciary will rise to the occasion to reassure the citizens that the foundational values of the Indian Constitution shall remain protected and secured.”He said delay in timely intervention on many constitutional matters leads to questions marks in the global community while also disheartening the people it concerns.At the same time, Sharma accused the BJP government of persecuting opposition leaders, referring to the legal troubles of former home minister and Rajya Sabha MP P Chidambaram and of Karnataka leader D K Shivakumar and other opposition leaders. “There can be differences of views but in a democracy, the rights of all citizens which are guaranteed under the Constitution should be protected. These concerns are bonafide concerns,” he said.“Are there two sets of rules and two sets of laws in the Republic of India — one that governs the opposition and one that benefits ruling party leaders,” Sharma asked.

This invention relates generally to methods for modulating light and more specifically to methods and arrangements for producing modulated light having linear gray scale in light modulating systems with a plurality of states, wherein the response time for the light modulator to modulate between the states may be longer than the duration of at least one of the time periods used to produce a desired gray scale intensity. It is well known that humans viewing successive images within short time intervals may perceive the images as a single or continuous image. For instance, cinematic motion pictures include a series of individual images; however, the individual images appear as a continuous image when viewed in succession above a certain frame frequency. This frequency has been called the critical flicker frequency and in many systems, the critical flicker frequency is roughly 60 hertz. Thus, in most situations, when the time interval for each image in a series is on the order of {fraction (1/60)}th of a second, the individual images become indiscernible. Certain display systems exploit this concept to produce images. For example, consider a display system consisting of an array of pixels, each pixel having only two states, ON and OFF. This type of display system is know as a binary display system. In such a system, the pixels switch between the two states, thus modulating light so as to produce images. Binary display systems are used in a variety of applications, including head-mounted, hand-held, desk-top and projection devices. Consider further that this display system is capable of switching the individual pixels between the two states at frequencies much greater than the critical flicker frequency. If a specific pixel is ON for half of the time and OFF for half of the time and the frequency of modulation is less than the critical flicker frequency, the pixel appears to flash. However, if the pixel modulates between ON and OFF at a frequency greater than the critical flicker frequency, then the pixel appears to be ON continuously, but the intensity appears to be half as great as the intensity if the pixel was in the ON state. Likewise, a pixel that is ON for one-fourth of the time and OFF for three-fourths of the time appears to have one-fourth the intensity of the pixel being always in the ON state, assuming the frequency of modulation is greater than the critical flicker frequency. This intensity variation in light modulating systems such as the one described above is known as gray scale. The greater the number of different intensities the system is able to produce, the greater the level of gray scale the system is said to have. In order to maximize the number of different intensity levels a system produces, the framexe2x80x94the time period during which a single image is producedxe2x80x94is typically divided into time segments or slots. In one common example, the duration of each slot is determined such that each slot is twice as long as the next shortest slot, and the total duration of all slots combined is equal to the frame duration. Each slot is then assigned to be either ON or OFF. Thus, if the frame is divided into eight slots of unequal duration as explained above, (e.g., having duration ratios of 1:2:4:8:16:32:64:128), the slots may be assigned ON or OFF in 256 ways (28=256) to produce 256 unique intensities. Such a system is called an eight-bit gray scale system since the eight slots may be represented by eight binary bits with, for example, a 1 representing the ON state and a 0 representing the OFF state. The demand to produce systems with more intensities, or greater levels of gray scale, is increasing as display system applications become more pervasive. However, if the system is incapable of modulating between states instantaneously, the speed with which the system switches between states may limit the level of gray scale the system is able to produce. For instance, if the response timexe2x80x94the time the light modulator takes to changes statesxe2x80x94is longer than the shortest slot, then the light may not be displayed for the correct amount of time during that slot to produce the desired intensity. Display systems are not the only systems that encounter the gray scale limitation caused by the light modulating speed. Any multi-state light modulating system that has a non-zero response time to switch between states may experience this restriction. For example, referring initially to FIG. 1, one example of a basic system for modulating light and generally designated by reference numeral 10 is illustrated. Light modulating system 10 includes a light source 12, a light polarizer 14 and a light modulator 16. Light source 12 is configured to direct light 18 toward polarizer 14. Polarizer 14 is configured to pass light of one polarization state, for instance horizontally polarized light (i.e., horizontal with respect to the orientation of the polarizer). Horizontally polarized light H is then directed toward light modulator 16. For this example, light modulator 16 may be any binary light modulating system that has a non-zero response time to switch between states. In the present example, light modulator 16 has an ON state, wherein horizontally polarized light 20 is allowed to pass through to a viewing area 22, and an OFF state, wherein no light passes through to viewing area 22. The state of light modulator 16 is controlled by a drive signal from controller 24. Thus, light modulating system 10 is configured to produce a temporal pattern of light directed toward viewing area 22. Having generally described the configuration and operation of light modulating system 10, a more detailed method for operating the system will now be described, continuing to refer to FIG. 1. As previously stated, light modulating system 10 is configured to produce a temporal pattern of modulated light directed toward viewing area 22. Depending upon the frequency with which the light is modulated, the pattern may appear to a human viewer as a series of flashes. This would occur, for instance, if the frequency of modulator 16 is less that the critical flicker frequency of the human eye. However, if the frequency is greater than the critical flicker frequency, then modulated light 20 would appear continuous and have an intensity corresponding to the fraction of time that modulator 16 is in the ON state. Thus, light modulating system 10 has the ability to vary the intensity of light 20 directed toward viewing area 22, even though the intensity of light source 12 remains constant. Light modulating systems such as system 10 and methods for operating them are well known in the art. For example, light modulating system 10 may be a miniature display system of the type disclosed in U.S. Pat. No. 5,596,451, which is incorporated herein by reference. Further, U.S. Pat. No. 5,748,164, which is incorporated herein by reference, discloses several methods for using such a system to produce images having gray scale and/or color. However, as described above, if any slots are deficientxe2x80x94have duration shorter than the response time of the light modulatorxe2x80x94the system may not produce the desired intensity when the specific intensity level requires the light to be ON during that slot. Thus, the system may not produce a linear gray scale response. A linear gray scale response occurs when the ratio of any two input signals is equal to the ratio of the output intensities resulting from the two input signals. For example, consider a four-bit gray scale system, including bits A, B, C, and D, each bit corresponding to a slot. Bit A, the least significant bit (LSB), determines the state (ON or OFF) of the shortest slot and has a time weight of 1; bit D, the most significant bit (MSB), determines the state of the longest slot and has a time weight of 8. The system is capable of providing 16 different intensities (24=16). Assuming a frame time period of {fraction (1/60)}th of a second, or 16.7 milliseconds, the duration of the slots associated with each bit are as follows: Bit Axcx9c1.1 milliseconds; Bit Bxcx9c2.2 milliseconds; Bit Cxcx9c4.4 milliseconds; and Bit Dxcx9c8.8 milliseconds. If the light modulator has a response time greater than 1.1 milliseconds, then the system will not properly display all 16 gray scale intensities. The reason for this is explained below. Referring to FIGS. 2a-d, the drive signal and light modulator response for each of the four slots is illustrated for a system that has a response time greater than the LSB. FIG. 2a illustrates drive signal 30 and light modulator response 32 for bit D. In this example, drive signal 30 is in the OFF state prior to bit D, and bit D requires the light modulator to be in the ON state. Therefore, at the start 33 of the bit D slot, drive signal 30 transitions from the OFF state to the ON state. The transition in drive signal 30 causes the light modulator, as indicated by light modulator response 32, to begin transitioning from the OFF state to the ON state. The light modulator is not yet completely switched into the ON state for a period of time equal to the response time, indicated by reference numeral 34. In this example, drive signal 30 is in the OFF state after bit D. Therefore, at the end 35 of the bit D slot, drive signal 30 switches from the ON state to the OFF state, causing the light modulator to begin transitioning from the ON state to the OFF state as indicated by light modulator response 32. The light modulator is not yet fully switched into the OFF state until a period of time equal to response time 34 has passed. Although it may appear that response time 34 would limit the light modulator""s ability to produce the desired optical response, this is not the case. The light modulator""s optical response as a result of bit D includes the entire period influenced by bit D drive signal 30, not just the light modulator response during the bit D slot. In other words, the optical response as a result of bit D is the integral of light modulator response 32 over the entire period influenced by bit D drive signal 30. This response equals the desired optical response that corresponds to the gray scale intensity represented by bit D being ON. FIGS. 2b and 2c provide similar illustrations for bits C and B, respectively. FIG. 2d illustrates drive signal 36 for bit A and corresponding light modulator response 38. As indicated by drive signal 36, the desired light modulator state is OFF both before and after the bit A slot. At the beginning 40 of the bit A slot, the drive signal switches to the ON state, at which time the light modulator begins to transition to the ON state, as indicated by light modulator response 38. However, because the light modulator has a response time 34 greater than the duration of the bit A slot, the light modulator is not able to switch completely to the ON state before the end 42 of the bit A slot. Thus, at the end 42 of the bit A slot, the drive signal switches to the OFF state and causes the light modulator to begin transitioning back to the OFF state. In this case, however, the light modulator does not produce the desired optical response, as explained next. In the three previous cases, the ON delay in the light modulator""s response at the end of the slot compensated for the OFF delay at the beginning of the slot. In the present case, the delays essentially overlap in time and the light modulator never reaches the fully ON state. Therefore, even though the delay at the end of the bit A slot partially compensates for the delay at the beginning of the slot, the two segments together are not of sufficient duration to produce the desired optical response. That is, the integral of light modulator response 38 over the period influenced by bit A drive signal 36 is less than the desired optical response that corresponds to the gray scale intensity represented by bit A being ON. Thus, conventional methods of producing gray scale such as this are limited in their ability to correctly produce linear binary gray scale in cases where the LSB slot time is shorter than the light modulator response time. Referring now to FIGS. 3a and b, another factor is illustrated that further complicates efforts to produce linear gray scale in a binary system where, for illustration, the LSB slot time is shorter than the light modulator response time. FIGS. 3a and b illustrate timing diagram 50, drive signal 52 and light modulator response 54 for a case where the LSB, bit A, is positioned in time between bits D and C. In FIG. 3a bits D and C have a value of 0, representing the OFF state, while bit A has a value of 1, representing the ON state. As described above with reference to FIG. 2d, the light modulator, as indicated by light modulator response 54, is unable to completely transition to the ON state within the bit A slot time. Thus, the integral of the light modulator""s response over the period influenced by the bit A drive signal does not produce the desired optical response that corresponds to the gray scale intensity represented by bit A being in the ON state. The integral of the light modulator""s optical response in this case is represented by the region designated by reference letter X. In FIG. 3b bit D has a value of 0, while bits C and A have a value of 1, as indicated by drive signal 56. When drive signal 56 reaches the point in time 57 when it represents bit C, the light modulator is still responding to the bit A signal. However, because bits A and C have the same value, the light modulator continues to transition toward the ON state. The integral of the light modulator""s response over the period influenced by the bit A drive signal is represented by reference letter Y. Although the LSB, bit A, has the same state in each of FIGS. 3a and 3b, the integrals of the light modulator""s response in each case, X and Y, are not equal. Thus, the light modulator""s response to the drive signal for bit A depends on the state of the light modulator before and after bit A. This factor further complicates the ability of conventional methods of producing linear gray scale in binary systems where the LSB slot time is shorter than the light modulator response time. The present invention overcomes the aforementioned limitations and provides a method of producing light having linear gray scale in multi-state systems where at least one slot is shorter than the light modulator response time. As will be described in more detail hereinafter, methods and arrangements for producing modulated light having grayscale are herein disclosed. The method includes providing a light modulator having grayscale based on a series of time intervals and having a plurality of light modulator states. The method also includes establishing the duration of each time interval such that the time intervals in the series have progressively varying duration. The method further includes determining a drive signal for each time interval that causes the light modulator to assume a specific light modulator state. The method further includes causing the light modulator to produce a desired time-averaged light level over the series of time intervals by in part driving the light modulator using the drive signal that corresponds to a particular time interval for a duration that is longer than the duration of the particular time interval, the particular time interval having duration shorter than the response time of the light modulator. The method may also or alternatively include sensing the temperature of the light modulator and determining the duration by which the drive signal corresponding to the particular time interval exceeds the duration of the particular time interval based in part on the sensed temperature. The method may also or alternatively include arranging the series of time intervals such that the light modulator is in the same state immediately prior to the particular time interval as the light modulator is in immediately after the particular time interval. The method may also or alternatively include arranging the time intervals such that the particular time interval immediately follows a first part of a longer one of the time intervals and immediately precedes a second part of the longer time interval. The method may also or alternatively include reducing the duration of the drive signal corresponding to the longer time interval by an amount of time that is related to the amount of time by which the drive signal corresponding to the particular time interval exceeds the duration of the particular time interval. In one embodiment of the invention, a light modulator has grayscale based on a series of time intervals. The light modulator also has a plurality of light modulator states. The time intervals have progressively varying duration and each time interval has an associated drive signal that causes the light modulator to assume a specific light modulator state. The light modulator includes a controller that causes the light modulator to produce a desired time-averaged light level over the series of time intervals by in part driving the light modulator using the drive signal that corresponds to a particular time interval for a duration that is longer than the duration of the particular time interval, the particular time interval having duration shorter than the response time of the light modulator. The light modulator also or alternatively includes a first arrangement that senses the temperature of the light modulator and a second arrangement responsive to the first arrangement that determines the duration by which the drive signal corresponding to the particular time interval exceeds the duration of the particular time interval based in part on the sensed temperature. The light modulator also or alternatively includes a controller that arranges the series of time intervals such that the light modulator is in the same state immediately prior to the particular time interval as the light modulator is in immediately after the particular time interval. The light modulator also or alternatively includes a controller for arranging the time intervals such that the particular time interval immediately follows a first part of a longer one of the time intervals and immediately precedes a second part of the longer time interval. The light modulator also or alternatively includes a controller for reducing the duration of the drive signal corresponding to the longer time interval by an amount of time that is related to the amount of time by which the drive signal corresponding to the particular time interval exceeds the duration of the particular time interval. The light modulator may be a ferroelectric liquid crystal display. Alternatively, the light modulator may be a nematic liquid crystal display, a plasma display or a micro-mechanical deformable mirror device.

A vehicle behavior control, a vehicle stability control (VSC) and the like, which controls a behavior of a vehicle by controlling at least braking power, performs a control assuming that a center of gravity of a vehicle, one of a parameter determining a controlled variable, is constant. Among the vehicles, there is a loading vehicle whose load significantly changes between a light load and the maximum load and whose center of gravity position changes between front and rear of the vehicle. Even if the vehicle behavior control is performed on such loading vehicle assuming that the center of gravity position is constant, there is a possibility of failing to provide sufficient control performance. Conventionally, considering the change in the center of gravity position between front and rear of the vehicle caused by the load change between the light load and the maximum load, there is an apparatus that performs braking power control. For example, as disclosed in Patent Literature 1, when the rear wheel braking power reaches the rear wheel braking power in the ideal front-rear braking power distribution during the light load, if the rear wheel is not in a slip state, there is an apparatus that performs the braking power control to increase a distribution proportion of the rear wheel braking power.

[A case of stage IV gastric cancer with multiple liver metastases surviving for more than 4 years by treatment with chemotherapies without surgery]. A 75-year-old male who with type 3 gastric cardia cancer with multiple liver metastases was initially treated with S-1 in July of 2005. After 4 courses of the treatment, the liver metastases became undetectable on abdominal CT scan, with reduction in size of the primary tumor of the stomach. After 7 months of S-1 treatment, however, the progression of the primary lesion was endoscopically detected, and irinotecan was administered, demonstrating primary tumor regression. When re-growth of the primary tumor was observed, 3 courses of paclitaxel treatment showed little effect and was replaced by docetaxel treatment for 5 months, which had a grade 3 adverse effect. The next 10 courses of 5-FU combined with methotrexate were applied for one year until the primary tumor showed enlargement. Then 12 courses of CDDP with S-1 were administered until now, and the size of the primary carcinoma is under control. The patient is being followed on an outpatient basis without any surgical treatment, while the liver metastases have not relapsed on abdominal imaging.

AR.OUND CITY HALL P OPULAR predictions last year that hIstory would remember the nineteen-eighties as a Republican decade, in which the Democrats could only hunker down and repent their sins, have now been stashed away by many Americans, along with such dated items as WIN buttons and alleg- edly authentic splinters from Amy Carter's tree house. However, in the face of a faltering economy and other developments that many believe have ominous implications for the Grand Old Party, Washington continues, for the short run at least, to be a Republi- can show. Or, at any rate, that is the word from local politicians who regu- larly travel back and forth between N ew York and the capital. This inter- city traffic is naturally nowhere near as heavy as it was in the era when Presi- dent Carter was eager to reward New York political leaders for having pro- vided the decisive bloc of electoral votes that put him over in 1976. Four years later, he was even more eager to have the favor repeated, and during some weeks in the summer and early fall of 1980 it would have been a chal- lenge to try to locate aNew York poli- tician of any importance-a Demo- crat, that is-who had not recently had a meal of some kind at the White House. Nowadays, the people invited to break bread at 1600 Pennsylvania Avenue are likely to be Republicans from the Sun Belt, leaving most Democrats feeling out of things, even as they scheme to improve their party's position in this fall's congres- sional and gubernato- rial elections. Last month, when Connect- icut Senator Christo- pher Dodd was seen serving as a gofer, fetching a drink for New York producer Joseph Papp at the Washington opening of Papp's "Pirates of Penzance," Dodd ex- plained, "There's not much of anything bet- ter or more important for me to do these days. I'm a Democrat" If he had been urged to had been "puffing" -as he described it-some of his credentials; specifical- ly, he had told reporters that during the Vietnam W ar he had been drafted and had ultimately served as a second lieutenant, whereas Pentagon records revealed that he had never been in the Army. Caputo eventually said that he was sorry "if I misspoke," resorting to a term that has been put to frequent use lately by White House aides trying to account for the President's occa- sionally imaginative use of figures Caputo's misspeaking was deemed to be beyond political indulgence, but it took so long for him to realize this that one local political pollster com- mented, "He's actually dead, but he's like a soldier shot in the middle of a charge who takes a few steps before he falls on his face," indicating the de- gree to which some people in the poli- ticians' world come to think of their trade in life-and-death terms-but failing to acknowledge the irony of knocking off the unfortunate Caputo metaphorically in a military setting. On March 12th, four days after Caputo finally withdrew, State Comp- troller Edward Regan, who had had the strong backing of State Chairman Clark in seeking the Republican nomi- nation for Governor, took himself out of that race, saying that he would prefer to run for reëlection to his pres- ent office. Regan, an attractive, easy- going Irish-American from upstate Erie County, had been routinely re- ferred to as the front-runner among the Republican guber- natorial candidates since he had entered that race, on Decem- ber 30th, and recent polls had shown that he would do better than any other Repub- lican against Mayor Edward Koch, who, from the time he an- nounced that he would be a candidate for Gov- ernor, on February 22nd, had been treated by most political com- mentators as if he had the Democratic nomi- nation locked up. Regan had said that he would "relish" the prospect of running against the Mayor, but he now gave as the ma10r reason for his wi hdrawal the drying CASTING PR.OBLEMS be serious, Dodd would probably have added, "Wait till next year." U NDER the circumstances, it is a matter for particular astonish- ment here-and, one would think, at the Republican National Committee- that in the second-most-populous American state, which Reagan carried in 1980, the President's party and its plans for this fall's elections should currently present a spectacle of footless disorder that one Democratic district leader happily described the other day as "pitiful." Sudden shifts in personae or plot can, of course, turn a political scene on end overnight. At the mo- ment, it seems that for N ew York Republicans almost any change could only be a big improvement. As of last week, the Republican state chairman, George Clark, had not come up with a senatorial candidate to run against Daniel Patrick Moynihan, the Democratic incumbent, who is up for reëlection this year, although it was over a month since Clark's origi- nal choice for the nomination, former New York Representative Bruce Caputo, had pulled out of the race. Caputo had had the backing of fifty- three of the state's sixty-two Republi- can county leaders, but this support had fallen to almost nothing late in February after it was revealed that he LEISURE T/M 85

Motor vehicle crashes are the leading cause of death for children from 1 to 14 years of age. The odds of motor vehicle crash injury to children aged 4 to 7 are 59% lower when riding in belt-positioning booster seats than when riding in safety belts alone, and rear seating can reduce the risk of death to child motor vehicle passengers by as much as 46%. Despite these facts, 90% of booster-age children are prematurely graduated to adult safety belts and 30% of children are permitted to ride in the front seats of vehicles. The proposed project will develop and evaluate an efficient process for disseminating preventive messages regarding booster-seats and rear seating to large numbers of parents via partnership with community preschool and daycare programs. Considerable research on other health topics indicates that persuasive and risk communication tactics have a greater likelihood of motivating the adoption of protective behaviors than do traditional messages. The current research will expand upon this premise by developing a novel five-minute video that is framed according to such efficacious risk communication guidelines. Specifically, the video will include crash test footage, portraying the power of crash forces and evoking high emotion by means of vivid imaging. Such communication tactics are known to motivate maximum behavioral change; however, the literature indicates that this method has not yet been employed in child passenger safety programming. The effectiveness of the video-based program will be piloted at two large and representative preschool/daycare programs, using two similar control sites for comparison. The program will engage the assistance of community-based coalitions and will include incentives for participating preschool/daycare staff. As part of the evaluativeprocess, caregivers will complete (a) pre-post knowledge and practice surveys regarding back-seat and booster-seat use and (b) pre-post risk estimations related to childhood motor vehicle hazards. In addition, researchers will observe booster seat and rear seat use in preschool parking lots before, during, and after program implementation. It is hypothesized that families exposed to the video-based program, compared to those in the control schools, will have (a) increased knowledge about causes of injury and reasons for booster seat and rear seat use; (b) a more realistic assessment of personal risk; and (c) greater use of booster seats and rear vehicle seats when age-appropriate. Long-term goals for the program, if effective, are to package it for district-wide adoption and broad-scale dissemination.

Description: Jamal Jeffries and his trash-talking, ball-hogging, team-hating ways get him booted out of the league. When his fancy accessories--crib, cars, ultra-fine girlfriend--dribble away as quickly as his career, a desperate, financially-strapped Jamal takes his last shot at crashing the boards. Transforming himself into female power forward "Juwanna Mann," Jamal scores a tryout with the only pro organization that will take him--the women's league. It's tough enough for Jamal/Juwanna to contend with fierce competition on the court and proper protocol in the ladies' locker room, but his identity crisis hits another snag when he falls for team captain Michelle Langford. Too bad Michelle is already tight with smooth-talking lady killer Romeo, a dawg with moves sprung straight from Jamal's old bad boy playbook. And when rapper Puff Smokey Smoke tries to score with Juwanna, there are more balls in play than Jamal knows how to handle. It's gonna take more than a heavily-padded sports bra for Jamal to bounce back, but by the buzzer, he'll learn that to be a better man--and ballplayer--he's gotta get in touch with his feminine side.

171My spirit is broken,my days are cut short,the grave awaits me.2Surely mockers surround me;my eyes must dwell on their hostility.3“Give me, O God, the pledge you demand.Who else will put up security for me?4You have closed their minds to understanding;therefore you will not let them triumph.5If anyone denounces their friends for reward,the eyes of their children will fail.6“God has made me a byword to everyone,a man in whose face people spit.7My eyes have grown dim with grief;my whole frame is but a shadow.8The upright are appalled at this;the innocent are aroused against the ungodly.9Nevertheless, the righteous will hold to their ways,and those with clean hands will grow stronger.10“But come on, all of you, try again!I will not find a wise man among you.11My days have passed, my plans are shattered.Yet the desires of my heart12turn night into day;in the face of the darkness light is near.13If the only home I hope for is the grave,if I spread out my bed in the realm of darkness,14if I say to corruption, ‘You are my father,’and to the worm, ‘My mother’ or ‘My sister,’15where then is my hope—who can see any hope for me?16Will it go down to the gates of death?Will we descend together into the dust?”

The present invention relates generally to the field of protector devices that protect a phlebotomist and the like from accidental puncture by an exposed needle. Specifically, the invention relates to a needle protector having two engageable halves that enclose the needle of a catheter assembly following use of the needle in a patient. Phlebotomists represent one sector of the health care industry exposed to risks arising from accidental skin puncture by used needles. Accidental skin puncture can introduce viruses, bacteria, and other elements present in the circulatory system. An increased awareness of the hazards of skin punctures has arisen with the advent of AIDS in the health care sector, since AIDS is reportedly transmitted via the circulatory system. In normal practice, using a terminal needle a phlebotomist draws blood from an individual to deliver blood into an attached syringe, directly into sampling tubes, or via a catheter assembly to collection bags for storage and subsequent use. Once the blood is drawn and the phlebotomist removes the needle from the patient's arm, there is risk of puncture from the exposed contaminated needle. During subsequent blood sampling, a phlebotomist risks needle puncture while inserting a vacutainer on the receiving end of the same or an in-line needle assembly. A phlebotomist also risks accidental puncture while replacing the old needle cover. Exemplary art protection devices, consist of a hollow cylinder having a large top flange designed to protect the phlebotomist from impalement. The needle point is guided and inserted into a small hole in the flange and the needle hub is snapped into place. Thus positioned, that pointed end of the needle extends into the hollow cylinder. A vacutainer, or other similar sample tube, can then be inserted into the opposite end of the device so that the needle point punctures the vacutainer stopper and a blood sample drawn from the patient is directed into the vacutainer. The sampling procedure may then be repeated, replacing the vacutainer for multiple sampling, or the entire device is discarded. This disposable device is then used to retain/contain the needle assembly for disposal. However, with such a design, it is difficult to insert the needle tip into the entry hole of the flange. The phlebotomist who does not have keen eyesight may take a long time in positioning the needle into the flange, or may miss the flange and receive a skin puncture. There is also risk of damaging the tip of the needle if the phlebotomist does miss the flange opening. The damaged needle tip may result in impaired flow through the tip, and other undesirable results. Thus, there is a need for a protection device that protects a phlebotomist from puncture by a used needle. Such a device may be utilized prior to sampling, for safe transport of the exposed needle, for sampling prior to disposal of the used needle, and for containing the used needle for disposal.

Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation. In recent experiments on isogenetic cancer cell lines, it was observed that exposure to high doses of anticancer drugs can induce the emergence of a subpopulation of weakly proliferative and drug-tolerant cells, which display markers associated with stem cell-like cancer cells. After a period of time, some of the surviving cells were observed to change their phenotype to resume normal proliferation and eventually repopulate the sample. Furthermore, the drug-tolerant cells could be drug resensitized following drug washout. Here, we propose a theoretical mechanism for the transient emergence of such drug tolerance. In this framework, we formulate an individual-based model and an integro-differential equation model of reversible phenotypic evolution in a cell population exposed to cytotoxic drugs. The outcomes of both models suggest that nongenetic instability, stress-induced adaptation, selection, and the interplay between these mechanisms can push an actively proliferating cell population to transition into a weakly proliferative and drug-tolerant state. Hence, the cell population experiences much less stress in the presence of the drugs and, in the long run, reacquires a proliferative phenotype, due to phenotypic fluctuations and selection pressure. These mechanisms can also reverse epigenetic drug tolerance following drug washout. Our study highlights how the transient appearance of the weakly proliferative and drug-tolerant cells is related to the use of high-dose therapy. Furthermore, we show how stem-like characteristics can act to stabilize the transient, weakly proliferative, and drug-tolerant subpopulation for a longer time window. Finally, using our models as in silico laboratories, we propose new testable hypotheses that could help uncover general principles underlying the emergence of cancer drug tolerance.

Five subtypes of receptors have been cloned and characterized in the melanocortin family. These G-protein coupled receptors (GPCR) stimulate the cAMP signal transduction pathway in many different tissues, mediating a wide range of physiological functions. Melanocortin 1 receptor (MC1R) is mainly expressed in melanocytes, monocytes, and mast cells, to mediate pigmentation of the hair and skin and to block inflammation. MC2R is expressed in adipocytes and adrenal cells, to mediate steroidogenesis in the adrenal gland. MC3R is present in the brain, hyphothalamus, heart, gut, and placenta, and has been associated with energy homeostasis and inflammation. MC4R is uniquely expressed in the brain, and controls feeding behavior, energy homeostasis, and erectile function. MC4R knock-out mice revealed the phenotype of hyperphasia and obesity. MC5R is found in a wide range of tissues and is considered to play a role for the exocrine gland system. With a plethora of physiological functions of melanocortin receptors, a large number of compounds have been designed and synthesized in search for potent agonists and antagonists. Early examples are synthetic peptides and peptide analogues that have been identified on the basis of endogenous agonist such as αMSH. These peptide agonists have been used to characterize the function of these receptors. NDP-αMSH is a highly potent and nonselective agonist of MC1R, 3R, 4R and 5R, and has been reported to attenuate food intake and body weight gain in rat models. A cyclic heptapeptide MT-II is an agonist with a similar non-selective profile, and its therapeutic use has been proven in clinical trials for the treatment of erectile dysfunction. HP-228, a peptide analogue with similar affinity for all four receptors, was in clinical trials for the treatment of pain and inflammation associated with surgery. Several small molecule agonists for the melanocortin receptors have been discovered to have significant activity in drug trials to search MC4R agonists for the treatment of obesity, sexual dysfunction or inflamation. For example, the Merck research group has discovered a series of potent and selective MC4R agonists, one of which demonstrated significant effect for augmenting erectile response in mice (J. Med. Chem. 2002, 45, 4849). The Chiron research group has discovered a series of guanidine compounds as agonists that have hyphophasic activity and thus anti-obesity effect in the ob/ob mouse model (WO 02/18327). On the other hand, the Bristol-Myers Squibb group has discovered a highly potent selective MC 1R agonist, which showed efficacy in an acute mouse model of inflammation (J. Med. Chem. 2003, 46, 1123). In view of the unresolved deficiencies of the various pharmaceutical compounds as discussed above, there is continuing need in the art for small molecule MCR agonists and pharmacological compositions that have improved pharmacological profiles. It is, therefore, an object of the present invention to provide novel compounds that are useful for the treatment of obesity, diabetes, sexual dysfunction, and inflammation. Specifically, the present invention provides a compound of formula 1 having agonistic effect against MCRs, in particular selective agonistic effect against MCR4, and pharmaceutically acceptable salt, hydrate, solvate, and isomer thereof. Another object of the present invention is to provide a melanocortin receptor agonistic composition comprising the compound of formula 1, and pharmaceutically acceptable salt, hydrate, solvate, and isomer thereof, as active ingredients, together with pharmaceutically acceptable carrier. In particular, the composition according to the present invention has potent effect for the prevention and treatment of diabetes, erectile dysfunction, obesity, and inflammation.

Five Arrested Over Killing of Policeman in Lagos The Lagos State Police Command said it has arrested five people in connection with the murder of a policeman at College Road, Ifako-Ijaiye area of Lagos, on Wednesday. Irate mob had killed a policeman and vandalised a patrol vehicle following the death of a youth who was said to have had scuffle with the police two weeks ago and died early Wednesday. Police Public Relations Officer (PPRO), Chike Oti, said that five people had been arrested in connection with the incident. Oti said the suspects had been transferred to the Homicide section at the State Criminal Investigation and Intelligence Department. He added that they would be charged for murder at the conclusion of investigation. Irate mob had descended on some policemen inside a packed police vehicle and succeeded in clubbing one of them to death. Oti had disclosed this in a statement, Wednesday, adding that “at about 1100hrs, at College Road, Ifako Ijaiye, Ogba, Lagos, a police patrol team stationed at a black spot in the location was attacked by an irate mob for a yet to be determined reason. “In the process, Sergeant Esiabor Collins with service number 260326, was attacked and killed. Also, the patrol vehicle was not spared by the rampaging mob which they vandalised.” Oti said preliminary investigation into the incident revealed that the mob, mainly youths had earlier that morning gone to Area ‘G’ Command, Ogba with the intention to overrun the police formation and commit arson but found it impregnable. “However, the Area Commander in-charge, spoke to them, promising to cause an investigation into their grievances which bothered on the death of a youth who allegedly died today 29/08/18, two weeks after an alleged encounter with some policemen. “At this juncture, it must be clearly stated that the police authorities in the state are unaware of any encounter with the deceased as no formal complaint was received to that effect,” he said. According to Oti, the Commissioner of Police, Edgal Imohimi noted that the penchant to take laws into own hands by some people who easily constituted themselves into a mob was becoming worrisome to say the least. “The Command wishes state that the deceased officer and indeed the entire patrol team had the option of defending themselves with their firearms against the mob but chose to show restraint in the face of provocation but unfortunately the rampaging mob never allowed them that option hence Sgt. Collins paid the supreme price. “The Commissioner of Police, Lagos State, CP Edgal Imohimi, notes that policemen in the state had on several occasions shown restraints in the face of provocative actions. He therefore warns that policemen may be forced to use their firearms to defend themselves, other people about being killed by a mob and in the protection of government assets. “He urges parents to warn their children to refrain from such acts which according to him may lead to a breach of the peace and unnecessary bloodletting,” Oti stated.

The present invention relates to an apparatus for sorting coins, in which a plurality of differently sized rectangular coin sorting slots are formed in a coin sorting plate, and a plurality of almost elliptical coin carrying slots are formed in a coin carrying vessel. Each of the coin carrying slots consists of a large arc and a small arc, and therefore, a large coin is settled into the large arc, while a small coin is settled into the small arc of the coin carrying slot. Accordingly, when the coin carrying vessel with the coin carrying slots formed therein revolves, a large coin drops into a large coin sorting slot, while a small coin drops into a small coin sorting slot. Thus the sorted and dropped coins are guided by a plurality of guides respectively, thereby making it possible to sort coins according to their sizes. Generally, in the commercial transactions and in the financial transactions, large quantities of coins are required at the transaction sites or at the financial organizations. Accordingly, there are the requirements that coins be accurately sorted, and these requirements are being increased day by day. Generally, the conventional coin sorting apparatus, such as disclosed in U.S. Pat. No. 4,275,751, includes: a coin carrying vessel for carrying the coins; and a coin sorting device for sorting the coins thus carried. The coins which are carried by the coin carrying vessel to the coin sorting device are sorted in the following manner. That is, when the coin sorting device revolves together with the coins, if the coins encounters a sorting hole, then the coins are discharged owing to the centrifugal force. The coins which are sorted in this manner are received into receiving vessels respectively according to their sizes. In this apparatus, the coin sorting device which sorts the coins according to their sizes are the principal part. In the above described conventional coin sorting apparatus, within the passage through which the coins rollingly pass, there are formed a plurality of coin sorting slots having different sizes respectively. Thus when the coins rollingly move through the above mentioned passage, if the coins fall into the coin sorting slots, then these coins are dropped and sorted. That is, a coin orbiting plate has a plurality of differently sized elongate slots, and when the coin orbiting plate revolves, the orbiting coins drop after passing through the elongate slots according to their sizes. The coin sorting apparatus in which the coin sorting slots are formed in the coin passage shows a slow sorting speed. Meanwhile, the coin sorting apparatus in which the coin orbiting plate having the plurality of coin sorting slots shows a low accuracy of the sorting. The present invention is intended to overcome the above described disadvantages of the conventional techniques. Therefore it is an object of the present invention to provide an apparatus for sorting coins, in which the sorting speed is high, and the sorting accuracy is also superior. In achieving the above object, the apparatus for sorting coins according to the present invention is constituted such that the sorting of coins is realized as soon as the coins are carried. Accordingly, the structure of the coin carrying device and the structure of the coin sorting device are different from those of the conventional coin sorting apparatus. The coin carrying device includes a plurality of coin carrying slots, and each of the coin carrying slots consists of: an arcuate portion of a large radius, and an arcuate portion of a small radius. Thus in the large radius arcuate portion, there can be settled a large coin, while a small coin can be settled in the small radius arcuate portion. Further, a plurality of coin sorting slots are formed on a coin sorting plate, and the coin carrying slots revolvingly pass over the coin sorting slots. The coin sorting slots are arranged around the coin sorting plate, and the sizes of the circularly arranged coin sorting slots become larger as advancing clockwise. The first coin sorting slot allows the smallest coins to be dropped through it, while the last coin sorting slots allows the largest coins to be dropped through it. The lower portion of the coins are supported at the round supporting lines until the last moment when the coins are dropped. So as to make sure for the coins to be supported at the round supporting lines, the large or small coins are made to contact with the small radius arcuate portion. As described above, the apparatus of the present invention ensures that the coins are sorted simultaneously with the their carrying. Therefore, the coins are put into the coin carrying vessel at a constant rate, and one coin can be put into each of the coin carrying slots. Accordingly, the thickness of the shell of the coin carrying vessel is made to be same as or smaller than the thickness of the thinnest coin. Even if two or more coins are stacked in one slot, the stacked coins are dropped when the coin carrying slot orbits to be overlapped with the next coin sorting slot.

As we know, at present, power generation is a production process of converting, using a power generation device, thermal energy and nuclear energy of petrochemical fuel (such as coal, oil and natural gas) into electrical energy supplied for needs of various departments of national economy and people's life. However, petrochemical fuel can produce large amounts of carbon dioxide, which exacerbates the global greenhouse effect. Besides, nuclear energy faces great challenges of source of raw materials and environmental protection. Those skilled in the art have begun to use solar energy, wind energy, geothermal energy, water energy (including marine energy) and other clean energies for power generation. However, solar energy and wind energy are seriously affected by climatic conditions, and geothermal energy and water energy (including ocean energy) are subject to harsh geographical conditions as well. Therefore, these energies cannot be popularized on a large scale. Furthermore, long-term development of the ocean energy is prone to result in ecological disasters. Therefore, a kind of energy which is cheap and can be widely collected is needed. As a result, ubiquitous air, oceans, lakes and rivers come into people's sight. As all the energies on the surface of the earth substantially come from the sun (energy caused by volcanic eruption is relatively weak and can be negligible), the energy of the sun's rays is heating air, oceans, lakes and rivers all the time. If the energy can be extracted for human use, it will no longer have the problem of emissions of carbon dioxide, ecological disasters and the problem of scarcity of resources. Besides, the energy will no longer be subject to climatic conditions and geographical conditions. For the above reasons, a variety of power generation devices making use of air or liquid have been developed, where air or liquid thermal energy is used to make working fluids having a low boiling point in a vessel be gasified, and then high pressure steam generated is used to drive a generator to generate power through a turbine. However, at present, such devices are basically required to realize liquefaction recycling of the working fluids by means of a refrigeration compressor and a booster pump. The problems lie in that, on one hand, as the refrigeration needs to face enormous liquefaction potential, it is infeasible to use the refrigeration compressor to liquefy the working fluids, and on the other hand, even if there is a ready-made cold source, using the booster pump to make the working fluids back into a high pressure area costs highly. Therefore, the devices have too low overall efficiency and cannot be applied in practice. In addition, such devices have special requirements on working conditions, that is, they require a temperature difference, and the greater temperature difference the better. The devices cannot work in the case of no temperature difference. In view of the above situations, it is necessary to improve the power generation devices, to improve the efficiency of power generation and finally realize all-weather, all-earth and full-time power generation and even provide power under no temperature difference conditions.

This invention relates to methods for embossing a pattern in a piece of glass. Hot glass is a relatively sticky material that tends to adhere to hot embossing tools. In the manufacture of glass articles, this sticking tendency is controlled by working the hot glass with chilled tools. Fine detail however, cannot be embossed in glass with chilled tools because a skin forms on the surface of the glass, which limits the fineness of the pattern than can be impressed. This skin inhibits the flow of the glass into the small detail of the embossing die. If the die temperature is increased to permit a greater glass flow, a condition will be reached where the glass will adhere to the tool making the embossing impossible. The adherence of molten glass to mold surfaces has been reduced by vibrating the mold while the glass was in contact with the mold as shown in U.S. Pat. No. 1,482,760 issued on Aug. 9, 1922 to J. A. Milliken. This vibration was heretofore used to eliminate the necessity for cooling the mold between separate molding operations. Carbon and graphite die materials have nonstick properties that permit their utilization in glass forming. However, these materials cannot be employed to emboss fine patterns because the details in the patterns are destroyed by the oxidation of the materials at high temperature.

Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion. 3,4-Methylenedioxymethamphetamine (MDMA) affects both dopamine and serotonin (5-HT) systems. One of its acute actions is to cause a reversible fall in steady-state brain 5-HT concentrations. To investigate the chemical basis of this acute effect, the brain levels of the parent compound and three major metabolites, 3,4- 3,4-methylenedioxyamphetamine (MDA), 3,4-dihydroxymethamphetamine (DHMA) and 6-hydroxy-3,4-methylenedioxymethamphetamine (6-OHMDMA), were monitored, together with 5-HT levels, over a period of 6 hr in male Sprague-Dawley (SD) rats. The temporal relationships between drug concentrations of both stereoisomers and depletions were evaluated first. There was no correlation between the concentrations of the compounds measured and the extent of 5-HT depletion. Brain levels of MDMA and MDA were higher than plasma levels and exhibited a stereoselectivity in that (-)-MDMA and (+)-MDA levels were higher than those of enantiomers. The relationship between the dose of ((+)-MDMA and reduction in 5-HT levels was next investigated in SD male, SD female, and Dark Agouti (DA) female rats. These animals exhibit different capabilities of MDMA metabolism. There is a lower level of MDA, the N-demethylated metabolite of MDMA, in female SD rats than in males. Female DA rats are deficient in CYP2D isozymes, one of the enzymes responsible for demethylenation of MDMA to DHMA at pharmacological concentrations of substrate. there was a significant accuulation of MDMA in the brain and plasma of DA rats, but their 5-HT depletion was somewhat attenuated. The results indicated that MDMA ++ was apparently not the single, causative agent for the acute 5-HT depletion, which may also involve a metabolite formed by CYP2D.

The Neural Correlates of Similarity- and Rule-based Generalization. The idea that there are multiple learning systems has become increasingly influential in recent years, with many studies providing evidence that there is both a quick, similarity-based or feature-based system and a more effortful rule-based system. A smaller number of imaging studies have also examined whether neurally dissociable learning systems are detectable. We further investigate this by employing for the first time in an imaging study a combined positive and negative patterning procedure originally developed by Shanks and Darby [Shanks, D. R., & Darby, R. J. Feature- and rule-based generalization in human associative learning. Journal of Experimental Psychology: Animal Behavior Processes, 24, 405-415, 1998]. Unlike previous related studies employing other procedures, rule generalization in the Shanks-Darby task is beyond any simple non-rule-based (e.g., associative) account. We found that rule- and similarity-based generalization evoked common activation in diverse regions including the pFC and the bilateral parietal and occipital lobes indicating that both strategies likely share a range of common processes. No differences between strategies were identified in whole-brain comparisons, but exploratory analyses indicated that rule-based generalization led to greater activation in the right middle frontal cortex than similarity-based generalization. Conversely, the similarity group activated the anterior medial frontal lobe and right inferior parietal lobes more than the rule group did. The implications of these results are discussed.

"Sync:" "Vayger :)" "Ah, the T-7 chip." "Digital gold." "Sweet." "Not this time, guys." "What's your hurry, handsome?" "Relax!" "I've gotcha!" "Scratch three losers." "Did you see that?" "Amazing!" "Terrific!" "Who are those guys?" "Magma, Freon and the 2-D Man." "Who is this terrific trio?" "Tonight we got the exclusive inside story." "Several months ago in the Beywritch Research Center prize winning physicist Dr. Mike Morgan, his fiance Merry Michels and lab assistent Stevard Low, were accidently exposed to dangerous levels of radiation during a partical fusion experiment." "We warn viewers, that the tape we're about to show, may be to intense for children." "Turn it up." "Cool." "The results." "There bodies underwent dramatic changes." "Now, these heros have promised to use there incredible abilities, to clean up Gotham." "The government has speared no expense in establishing there new base of operation." "The Trio tower." "United in there war of crime, here comes the Terrific Trio." "Looks like, I'll be having more time to do my homework now." "We'll see." "Wait, just a little more time." "That's all I'm asking." "Hope you have better luck." "This is Gordon." "Finally." "Someone with a real line of credit." "No deals, until I know, the hostages are safe." "Sweetheart, I've already been through this with your cub scouts." "I'm lookin' at my foreign account right now and still no donations." "Better hurry, love." "Telefon's over in 5 minutes." "Should we go in?" "We can't take the chance." "That's counselor Green's family in there." "Guess who?" "Hey!" "What's the matter, boys?" "Cold feet?" "Wrong door, Einstein." "Move in!" "Let's go!" "Let's go!" "Freeze!" "Been there, done that." "Don't let 'em hurt me!" "We'll take it from here." "Right." "Hey, that's police property." "You tell 'em." "You saw the way, she looked at me." "We're freaks." "Michael, please." "I can't even hold you in my arms anymore." "It's hard for all of us." "I can imagine, my dear." "You would have to imagine, if you'd been there." "Yeah, I'm still trying to figure out that budget meeting, you went to that night." "What are you implying?" "Calm down, Mike." "It's not like he knew, this was going to happen." "Marry, you know, how much I care for you." "All of you and we're doing everything we can, to find a cure." "You should let me help." "Michael, you can't even touch a test tube without melting it." "Better you stay here, where you can do some real good." "How are they?" "Angry, frustrated, confused." "You promised, you could control them." "Give them time." "It's a big adjustment." "I hope your right, Dr. Hodges." "'Cus heaven help us, if you're not." "Hey, Magma underwear." "Shway." "Yeah, it's great to finally have clean holesome heroes, that kids can look up to." "Those guys are twips." "Batman rips." "You think?" "Big time!" "How about an ice cream?" "My treat." "Sure." "What's the catch?" "These are the Trio's latest DNA scans." "Has anyone seen this?" "No, sir." "Run them again." "We've gotta be absolutely certain." "Yes, sir." "General Norman." "We've got a problem." "I don't know, why you even bothered to send me out." "With a Terrific Trio around, there's not even a purse snatcher in site." "Hold on." "I'm picking up a hot spot on the infrared." "A fire." "Or a weenie roast." "I'll check it out." "What is it?" "It ain't Smokey the Bear." "Magma." "Working solo tonight?" "Out of my way." "How about showing a fellow civil servent some profesional courtesy." "And I thought, he was one of the good guys." "I can't believe you broke into the lab." "Why would you take such a risk?" "I had to know the truth." "But, Hodges said..." "Hodges lied." "See for yourself." "We'll be like this forever." "No." "It's worse then that." "What happened?" "We're under attack!" "It's general Norman!" "We've been double crossed!" "Hit 'em hard!" "Don't let 'em get away!" "Now, the army's attacking." "I thought they were the good guys too." "McGinnis, get out of there now!" "Fire!" "Terry!" "Fire!" "After 'em!" "Stand back!" "They're heading for the hanger!" "I see them!" "Let's take them down, major!" "This is Eagle One." "Target has been eliminated." "Station your men at all the entrances." "I want that tower secured." "You heard the general." "Those freaks ar history." "I don't think so." "The car was just a decoy?" "See for yourself." "It's not ovet yet." "I know they were your friends, Dr. Hodges." "But you, yourself, said, there condition was deteriorating and eventually they would have become dangerously psychotic." "Hello, Howard." "We have to talk." "We've been reviewing the data on the particle fusion experiment." "According to your notes, you knew about the danger." "No!" "I had no idea, this would happen!" "Just a freak accident?" "Yes." "One in a million." "Wait!" "Wha..." "What are you doing?" "Finishing, what we started." "But, you can't." "Why not?" "You'll kill us all!" "Once it reaches critical mass, the radiation can't be contained!" "Then you knew all along." "Yes." "That's why you weren't there that night." "Yes and you're not suppose to be either." "What?" "Michael had it all." "The brains, the success, your affection." "I figured, with him out of the way, I'd have a chance." "You figured wrong." "Please, turn it off." "No." "But the whole city will become a hot zone." "You're crazy." "I believe, your words were, dangerously psychotic." "We are, what you made us." "Party's over." "Finish it." "Now!" "No!" "Michael!" "I gotta shut that thing off!" "Thousands of people will die!" "Ma..." "Dr. Morgan." "You can't let that happen." "You're a hero, remember?" "No." "I'm an accident." "Where heroes, they make a choice." "I never did." "No." "You're staying for this." "Satisfied?" "No." "You don't understand." "I was there friend." "Right." "Sync:" "Vayger :)"

Intermediary Nodes or proxies are important and necessary in many deployments of various application layer protocols such as e.g. Hypertext Transfer Protocol (HTTP), Hypertext Transfer Protocol Secure (HTTPS), Message Session Relay Protocol (MSRP), Session Initiation Protocol (SIP), Constrained Application Protocol (CoAP), etc. One of the most important use cases are HTTP proxies which are universally deployed in e.g. enterprises, operator networks, hotels, and airports. Another example is MSRP proxies which are abundant in MSRP deployments. Intermediary Nodes, which may alternatively be referred to as intermediate nodes, perform services, such as e.g. traffic optimization, caching, antivirus protection, downlink content screening and filtering in e.g. schools, uplink content screening and filtering in enterprises, and message storage in the case of messaging protocols, such as e.g. MSRP. There exist solutions for the Secure Real-time Transport Protocol (SRTP), such as e.g. in WO2010/003713 A1. However, these known solutions are not applicable for the mentioned scenario, since these solutions target another trust model where the proxy is simply not trusted to access content at all. Thus, in these solutions the proxy will not gain any access to desired content. Secondly, the aforementioned SRTP solutions use tunnel-in-tunnel and multiplexing mechanisms with additional (in our case unwanted) overhead. Thirdly, these types of solutions are SRTP-specific and do not work with TLS. Known 3GPP IMS related mechanisms as disclosed in 3GPP TS 33.828, by which an IMS network may add/replace a Client offer for e2e security with a “hop-by-hop” security, do not offer any control or consent from the endpoints. Also, they are tightly integrated with IMS protocols (SIP, SRTP) and do not work for TLS. Many of these application layer protocols are protected with Transport Layer Security (TLS), or Datagram Transport Layer Security (DTLS), since they can provide strong security and represent “standard” ways to protect TCP or UDP traffic implemented in most Clients and Servers. In most cases TLS or DTLS is setup before the application protocol is used. With TLS, we hereby mean all versions of TLS and its derivatives like DTLS. When the communication is not protected with TLS, an Intermediary Node may in most cases insert itself into the communication path, i.e. by interposing itself it can potentially eavesdrop, inject, or modify traffic between sender and receiver, causing what can be referred to as “traffic intervention”. When TLS is used, each Intermediary Node has only three choices, let the Client setup TLS end-to-end with the Server, break the TLS security model, or attempt to block the traffic. Common to the three options is that in most cases the Client and the Server are not aware that there is any Intermediary Node in the communication path. If an Intermediary Node has “silently” broken the TLS (end-to-end) security model, how does the TLS Client/Server know that their traffic is not subject to unauthorized access? Furthermore, one or more “friendly” Intermediary Nodes in the communication path still have no way of making their presence known to the TLS Client or TLS Server even if it wants to. As neither the Client nor the Server is aware of the Intermediary Node/s and their identities, they cannot include them in its communication, meaning the Intermediary Node/s must either resort to block the traffic, i.e. disabling the Client/Server communication, or it can let the traffic pass, but then it cannot fulfil the service as intended. Even though we have referred to TLS Clients and TLS Servers above, it will be evident from the following text that corresponding, intermediary related problems can be relevant also in scenarios where TLS is, not used, or at least initially not used.

[Tuberculosis in 0-14 year-olds in Cuba (1994-2003)]. Tuberculosis in infants and children is a sign of continuous transmission. The present article describes the distribution and the trend in incidence rates of new tuberculosis cases in 0-15-year-olds in Cuba. Incidence rates and their trend were estimated by provinces and age groups for the 1994-2003 period. Distribution and overall variation percentages, annual average rates, and rates and percentages according to classification were determined. The incidence rate decreased from 0.76 x 10(5) in 1994 to 0.31 in 2003 (59.2% of the overall reduction and 6.6% of the annual average reduction). The highest rate (1.06 x 10(5)) was found in 1995 (26 cases). In almost all provinces, the incidence trend decreased, except in the City of Havana, Sancti Spíritus, Santiago de Cuba, and the Isle of Youth. Childhood tuberculosis was mainly pulmonary (69.6%). Among the affected population, the highest percentages were found in the groups aged 10-14 years (35.6%) and 1-4 years (35.2%). Tuberculosis is infrequent and is extremely uncommon in infants. Notification is low throughout the country and the overall trend shows a steady decrease.

ABSTRACT Periodontal disease is a chronic inflammatory condition associated with gingival tissue breakdown and alveolar bone loss. No single organism has been implicated as the etiologic agent of periodontal disease, rather it is thought to be mediated by a dysbiotic oral community. Immune system dysregulation is hypothesized to be involved in driving the microbial community toward a dysbiotic state. As well, ecological succession and cell- to-cell interactions are hypothesized to play critical roles in community assembly in states of both health and disease. Molecular sequencing based methods provide exhaustive lists of organisms and genes present in a community such as that in the human oral cavity. However, these methods provide little information on how microbes are arranged in space in states of health and how the structure of complex oral microbial communities contributes to community function and disease progression. The goal of the research proposed here is to further develop a microbial imaging technology for mapping the systems level spatial structure of human oral microbial communities. Spectral imaging, combined with fluorescence in situ hybridization will be employed to map the spatial distribution of 8-15 different taxa of microbes in intact subgingival biofilms on teeth and in laboratory-grown mixed species cultures. An in vitro dental plaque microcosm model system will be developed to test the hypothesis that Fusobacterium nucleatum functions as an important bridge organism that unites early colonizing bacteria with late colonizing species. Dental plaque and saliva samples will be collected from 10 healthy volunteers after giving informed consent. Plaque samples will be used to seed microcosm cultures that will be grown in the laboratory. Oral microcosm communities will be supplemented with cultivated isolates of F. nucleatum to assay its effect on biofilm structure and complexity. This study will lay the groundwork for future controlled experiments to understand the effect that specific organisms have on the systems level spatial structure of complex oral microbial communities.

Chemotherapy-induced neutropenia as a prognostic factor in patients with metastatic pancreatic cancer treated with gemcitabine. Chemotherapy-induced neutropenia (CIN) is a common side effect of chemotherapy and an important dose-limiting factor. However, an association between CIN development and longer survival was recently reported in several solid cancers. In the present study, we aimed to assess whether CIN could be a prognostic factor and clarify other prognostic factors for patients with metastatic pancreatic cancer. We retrospectively analyzed the medical records of 84 patients who received gemcitabine monotherapy as first-line chemotherapy for metastatic pancreatic cancer to assess whether CIN could be a prognostic factor. Potential prognostic factors of survival were examined by univariate and multivariate analyses using the log-rank test and Cox proportional hazard model, respectively. Median survival time was 170 days [95% confidence interval (CI), 147-193] in patients without CIN (grade 0), 301 days (95% CI, 152-450) in patients with grade 1-2 CIN, and 406 days (95% CI, 271-541) in patients with grade 3 CIN. The multivariate analysis revealed that a pretreatment C-reactive protein level of <0.50 mg/dL [hazard ratio (HR), 0.534; 95% CI, 0.323-0.758, P = 0.015] and grade 3 CIN (HR, 0.447; 95% CI, 0.228-0.875, P = 0.019) were independent favorable prognostic factors in patients with metastatic pancreatic cancer treated with gemcitabine. Neutropenia during chemotherapy was associated with increased survival of patients with metastatic pancreatic cancer. Monitoring of CIN could be used to predict treatment responsiveness.

X-ray devices used in the medical field contain an X-ray tube which typically includes a cathode which is heated to emit electrons, a (typically rotating) anode having a target surface facing the cathode, and a surrounding glass and/or metal frame containing an X-ray-transparent window secured by a window mount. Some emitted electrons strike the target surface at a focal point and produce X-rays, and some of the X-rays exit the frame as an X-ray beam through the X-ray-transparent window. Other emitted electrons do not produce X-rays and are backscattered when they strike the focal point on the target surface. Many of the backscattered electrons go on to strike and heat the frame including the X-ray-transparent window and the window mount. It is known to place an electron collector between the focal point and the X-ray-transparent window to capture backscattered electrons that would otherwise strike and heat the X-ray-transparent window, wherein the electron collector has a central hole to permit passage of the X-ray beam. The heated frame is typically cooled by a liquid coolant, such as oil or water, located between the frame and a surrounding casing. The dissimilar coefficients of thermal expansion of the X-ray-transparent window and the window mount generate mechanical stresses which can cause tube failure. Additionally, high temperatures in the X-ray-transparent window itself can induce boiling of the adjoining liquid coolant. Such coolant boiling will degrade the quality of the X-ray beam which exits the frame through the X-ray-transparent window. Existing grounded metal frame tubes include those having high-cost components to mechanically join the window to the rest of the frame while reducing thermal stresses to acceptable levels. Some known tubes have enhanced cooling applied to the window region. It is also known that the backscattered electrons can create a thermal hot spot on the frame and can burn a hole through a glass frame. Such hot spot is located on the frame apart from the X-ray-transparent window and the window mount. Reducing the power of the X-ray beam and/or increasing cooling to the thermal hot spot region are known techniques used to overcome this problem. What is needed is an improved X-ray tube design which reduces heating of the X-ray-transparent window and the window mount from backscattered electrons.

The present invention relates to a method and system for incremental database maintenance, and in particular to updating materialized views in a database. In a data warehouse, views are computed and stored in the database to allow efficient querying and analysis of the data. These views stored at the data warehouse are known as materialized views. In order to keep the views in the data warehouse up to date, it is necessary to maintain the materialized views in response to the changes at the sources. The view can be either recomputed from scratch, or incrementally maintained by propagating the base data changes onto the view so that the view reflects the changes. Incrementally maintaining a view can be significantly cheaper than recomputing the view from scratch, especially if the size of the view is large compared to the size of the changes. The problem of finding such changes at the views based on changes to the base relations has come to be known as the view maintenance problem and has been studied extensively. Traditional maintenance techniques propagate insertions and deletions from the base relations to the view through each of its operations. Several improved schemes have been proposed for incremental maintenance of view expressions. However, problems arise with traditional techniques and with prior improved schemes. For example, none of the previously known schemes efficiently handles the case of general view expressions involving aggregate and outerjoin operators. As another example, most of the incremental maintenance approaches compute and propagate insertions and deletions at each node in a view expression tree, which is often inefficient. A need arises for an incremental maintenance technique which efficiently handles general view expressions involving aggregate and outerjoin operators. The present invention is a method and system for incrementally maintaining a database having at least one materialized view based on at least one table. When changes to the table are received, a change table based on the received changes is generated. The generated change table is propagated upwards to form a higher-level change table and the materialized view is updated by applying the higher-level change table to the materialized view using a refresh operation. In one aspect of the present invention, the change table includes a plurality of tuples representing the changes and the materialized view includes a plurality of tuples. The refresh operation has two parameters, a join condition and an update function specification. The materialized view is updated by finding all tuples in the materialized view that match the tuple in the change table, using the join condition, for each tuple in the change table and updating each found tuple in the materialized view by performing operations indicated by the update function specification. In one embodiment of the present invention, the materialized view is an aggregated materialized view. In this embodiment, each tuple in the materialized view and in the change table includes at least one aggregated attribute and may include one or more non-aggregated attributes. Tuples in the materialized view that match the tuple in the change table are found, using the join condition, by matching the non-aggregated attribute of a tuple in the change table, if any, with the non-aggregated attribute of a tuple in the view. Each found tuple in the materialized view is updated by updating the aggregated attribute of the tuple in the view using the aggregated attribute of the tuple in the change table. In one aspect of this embodiment, the materialized view is further updated by inserting a tuple from the change table into the materialized view, if no tuples are found in the materialized view that match the tuple from the change table, and deleting a tuple from the materialized view, if an aggregated attribute representing a count of a number of tuples in a group represented by a the tuple becomes zero. In another embodiment of the present invention, the materialized view is an outerjoin materialized view based on a plurality of tables. In this embodiment, there is a tuple in the materialized view corresponding to each value of at least one selected attribute in any of the plurality of tables. Each tuple in the materialized view comprises at least one selected attribute and at least one other attribute. Tuples in the materialized view that match the tuple in the change table are found, using the join by matching the at least one selected attribute of a tuple in the change table with the at least one selected attribute of a tuple in the view. Each found tuple in the materialized view is updated by updating the at least one other attribute of the tuple in the view using the at least one other attribute of the tuple in the change table. In one aspect of this embodiment, the materialized view is further updated by inserting a tuple from the change table into the materialized view, if no tuples are found in the materialized view that match the tuple from the change table and deleting a tuple from the materialized view, if a value of the at least one selected attribute of the tuple is no longer present in any table.

Various approaches have been suggested to address various thermal management issues (e.g., inlet air cooling, waste heat recovery) in gas turbines, gas turbine engines, internal combustion engines and other industrial processes. Such approaches include those discussed in the report entitled Experimental and Theoretical Investigations of New Power Cycles and Advanced Falling Film Heat Exchangers by the U.S. Department of Energy in conjunction with the University of New Mexico. In this report two new thermodynamic cycles were proposed and investigated based on the second law of thermodynamics. Two computer programs were developed to find effect of important system parameters on the irreversibility distribution of all components in the cycle: (1) the first cycle was based on a combined triple (Brayton/Rankine/Rankine)/(Gas/steam/ammonia) cycle capable of producing high efficiencies; and (2) the second cycle is a combined (Brayton/Rankine)/(gas/ammonia) cycle with integrated compressor inlet air-cooling capable of producing high power and efficiency. The proposed cycles and the results obtained from the second law analyses of the cycles were published in Energy Conversion and Management and ASME proceedings (IMEC&E 2001). Given the above, there is a need in the art for systems that are designed to address various thermal management issues for various devices (e.g., gas turbines, gas turbine engines, industrial process equipment and/or internal combustion engines). In one instance, there is a need for a system that is able to address various thermal management issues (e.g., inlet air cooling) in gas turbines, gas turbine engines, internal combustion engines and/or other industrial process equipment.

A device for producing beer is known, containing a system of communicated pipe-lines, a mash wort brewing unit and a low pressure steam-generator connected thereto, a filtrating chan, a hydrocyclone unit, cylindrical reservoirs arranged vertically for fermentation and after-fermentation with cooling jackets, a unit for cooling wort, a tank for hot water, a container for gathering brewers' yeast (See patent document RU No2039801 cl. C12C 11/00 05.07.93). However, the known device is not designated for operational delivery to the consumer of beer without loss of taste properties and its realization will cost much. The closest prior art for the claimed device is a device for producing beer comprising interconnected by a communicating system a device for beer wort brewing, a cooler, N units for fermentation, where N is an integer, K units for after-fermentation, where K is an integer and a cooling system (see patent SU 1817791 cl. C12C 13/00, 12.03.92). However, the known device requires great expenses to deliver and store finished non-filtrated beer to the consumer, and to organize its sale, and it does not guarantee preservation of the natural taste properties, as the time of storage of non-filtrated beer without strict temperature regime is limited to 3-4 days. A unit for after-fermentation is known, used in the said known device, comprising an isothermal vessel in insulated enclosure, having a cooling jacket and functional valves (See Patent document SU 1817791, cl.C12C 13/00, 12.03.92). However, the structure of the known device is of stationary type, which makes it impossible to use for operational delivery of non-filtrated beer at a point of dispense and sale. The basis of the invention is the problem of creation of a device that can reduce expenses for beer realization to the consumer, preserving its taste properties with the help of exclusion of intermediate operations of non-filtrated beer delivery, transfer procedures and providing optimal regime for its storage. Another problem is to create the structure of a unit for after-fermentation, which makes possible qualitative non-filtrated beer dispensing from it not only in the place of production, but also in any beer-dispensing section within a region or a city. The problem is solved in that a device for producing beer, comprising a device for beer wort brewing, a cooler, N units for fermentation, where N is an integer, K units for after-fermentation, where K is an integer, and a cooling system, interconnected by a communicating system, according to the invention, further comprises i-number of communication units, necessary for operational connection and disconnection of i-number of said K units for after-fermentation, where i—is an integer, equal to or less than K, and each of i-number of units for after-fermentation is embodied in such a way so that it is transportable, thermally insulated, hermetic, protected from deposited yeast mixing with non-filtrated beer during transportation, and can be connected to a cooling system, arranged at a point of dispense and/or sale, and the inner volume of each of i-number units for after-fermentation does not exceed 0,8 of inner volume of a unit for fermentation. According to another subject of the invention, a unit for after-fermentation comprises an isothermal vessel with a cooling jacket and is made with the possibility for operational connection, disconnection and transportation with finished beer at a point of sale and/or dispense, or beer at the stage of after-fermentation to another place of after-fermentation with the possibility for its dispense and/or realization. The bottom of an isothermal vessel comprises deposit space, which can have a conical shape with an angle between generatrixes in an axial plane of its cross section, constituting ≦90° or it can have the form of a cylinder, and the volume of deposit space may be equal to 0,01÷0,1 of the isothermal vessel's volume, and the isothermal vessel can be arranged on a common base on supports in an insulation shell with a housing. Furthermore, it can be provided by a fitting box with measuring devices, functional valves and joints for operational connection and disconnection, communicated by corresponding pipe-lines to the inner space of the isothermal vessel and to its cooling jacket. The essence of the invention is in the fact that the implementation in the above mentioned manner of units for after-fermentation and the introduction of necessary quantity of additional communication units makes possible the realization of operational connection and disconnection of units for after-fermentation, and transportation of non-filtrated beer with the possibility to connect them to cooling system at the place of sale and/or dispense, to provide preservation of taste properties for a long time. No intermediate operations on delivery and dispense procedure are made, which leads to reduction of expenses for beer-realization to the consumer.

Arm and leg substrate utilization and muscle adaptation after prolonged low-intensity training. This review will focus on current data where substrate metabolism in arm and leg muscle is investigated and discuss the presence of higher carbohydrate oxidation and lactate release observed during arm compared with leg exercise. Furthermore, a basis for a possible difference in substrate partitioning between endogenous and exogenous substrate during arm and leg exercise will be debated. Moreover the review will probe if differences between arm and leg muscle are merely a result of different training status rather than a qualitative difference in limb substrate regulation. Along this line the review will address the available studies on low-intensity training performed separately with arm or legs or as whole-body training to evaluate if this leads to different adaptations in arm and leg muscle resulting in different substrate utilization patterns during separate arm or leg exercise at comparable workloads. Finally, the influence and capacity of low-intensity training to influence metabolic fitness in the face of a limited effect on aerobic fitness will be challenged.

I'm campaigning for the local Labour party. Hello Peterborough! This is a very big political moment for the country. It's quite crazy, obviously, growing up here to see it in the national spotlight, it's quite scary. It's like the barometer of the whole nation really, like the last bastion of hope type of thing. I've seen the way this town has been shafted over the years, to be honest. … this isn't even about Brexit, this is about the kind of country we live in. … people transform our society, so we won't be one that's so divided, we won't be one where we walk by on the other side for those that are unfortunate. I mean, with the odd break, this is about 14 days on the road now. Frimley, Manchester, Swindon, Thornbury on the edge of the Cotswolds. Look at that, we've got to go and get a shot of that. That was post apocalyptic. GPS: At the roundabout, take the third exit. Peterborough has got everything really that sort of denotes modern Britain for good and ill. It's got loads and loads of warehouses and distribution centres. It has got a huge population of people from EU countries, and other countries besides, and it voted by a pretty heflty majority for Brexit. You know there's a giant bird cack down your windscreen I've kept that there for symbolic purposes. It's to indicate the fact we're being that we're being shat on. I wanted to send a message, because we are sick and tired of the establishment. I am here to support it and teach the elite a lesson. Tell me about your idea of the elite, who are the elite? Well, the elite are the same people who control the Guardian now and are putting through your neocon agenda. Wow! So where are you coming from politically? Well, it depends, I'm a supporter of Julian Assange, which the Guardian isn't, I'm a supporter of Bradley Manning, which the Guardian isn't. Left and right all joins. Right. I also blame the free markets, but I don't think they have the free markets anymore. We have crony capitalism. Big queue. In any given political situation, someone's got a big queue, you know, It was sort of, Corbyn two years ago, wasn't it? And it was Scottish independence, a year or two before that. These MPs are payed about £75,000, they voted in to do what … ... our bidding. But they're not doing it ... What we tell them to do, but they don't ... They're going off on a tangent ... Respect the people. I've watched some of these on the internet and I thought: 'oh, this sounds intersting' and he's got a very, very powerful message. The British political class is rotten to the core. Parliament has abolished the referendum and declared war on the British people. Welcome to the stage, Nigel Farage! And trust me, trust me, there are shitloads, a lot more people feel like this. A lot more people. And don't think this movement, and it is a movement now, that means nothing still, that's what they think, it means nothing still. Wait until after this European election, and then Peterborough, when we win that too. Who are you fighting? Everybody. This part of Manchester is at the other end of the Brexit spectrum. I'm just freestyling here, guys. You're sort of freestyling about topical things… I obviously, you know, share the concern about Brexit but at the same time, I am not knowledgable enough to share, you know, a prevalent opinion. What's your sense of the future? Are you feeling optimistic or pessimistic? Optimistic, absolutely. You know, my journey now is just to carry on creating, that's cool with me. I don't… You don't see any sort of… I'm a bit older than you, I feel there's a lot of dark clouds on the horizon, the world's not going in a very nice direction. Yeah, but for what I can do as an individual, I just think it's about being, you know, on an individual to individual basis, just being positive with one another, that's sort of the easiest way to effect change. You are the one man antidote to the bleak mood. I've stopped watching the news because it's like, what's the point, it's just the same stuff, different day. You tuned out? Yeah. Just because I've got more important things to think about now. What like, one on the way? Yeah. What kind of world do you think you're bringing your baby into? I don't know. You're talking to the wrong guy. You must have an opinion. My opinion is, don't worry about the country, worry about yourself. Really? There's nothing else you can do. If you worry about the country, what can we do about it? This is where vox pops are simultaneously completely unscientific and random ... But also, very revealing. About three days ago we were in Surrey, at a Nigel Farrage rally. and I know exactly what they want, Brexit now, right? The people I've spoken to here seem much more … I'm just politically confused. Do you know about Change the UK, the independent group? Yeah, don't start ... Why you're laughing? You know why I'm laughing. Speaking of being politically confused, there's an event in the centre of town put on by the other new party, trying to use these elections to make a big breakthrough. No queue here as yet. It's like a gate at an airport. The Change UK flight to Romania is now ready for boarding. We've decided that we could no longer put up with politics as it was. We'll come to that, we are just whetting your appetite for it. That's what we're going to do in a second. So … ah! While we find our wi-fi connection… I want to stand on a platform to rebuild something, to reshape and to change our politics. We are campaigning, if we're going to go off the cliff in October to revoke article 50. It's not quite funny but it's not bad. It's the way in which my community is dismissed, the way which is smeared as some liberal metropolitan elite, it's disgusting. We have to walk, otherwise I am going to miss this train, and I'm going to be killed if I miss it. You should have called yourself the remain party, shouldn't you? No, because the broken nature of our politics is far beyond Brexit. You're not going to out with a whimper, you don't worry about that? No, God no. I mean, I wouldn't… Apparently were these narcissistic, egotistical careerists ... we've done like the most non-careerist thing you can think of. Hi mate, are you alright? So what happens next? I hear there's infinite possibilities so … Infinite possibilities. Right, go and get your train. I am going as well! There they go. Change UK. Well considering how het up everyone's got about this election, it's a little bit tumbleweedy. Not by the look of it. What, because two people have got in to vote? It's not exactly South Africa. It's not like Nelson Mandela. You can't tell us how you voted, could you? I wish I could. Who did you vote for? Brexit. Did you? Yeah. I mean, you know the fella in charge of of the Brexit party, Nigel Farage? A great fan of Mrs Thatcher and all that. Well aren't they the people who did for Merthyr not that long ago. You can't keep going back in history, can you? What do people say leave the EU to make things even worse? I don't believe it. They said the day we voted out. Everyone said that the European Union has put so much into Merthyr, and they have. You know, we've got a nice bridge, you know, we've had a lot of funding, but it doesn't help us. Do you work? Yeah. What do you do? I'm a gardener. What do you do? Healthcare. You know, there's always a struggle. I don't know, it's the same as it's always been. And that's why we need to change. Radio presenter: It's Friday for most of us today, Some warm sunshine around as well. There'll be some changes coming in to the south-west … We drove across the social spectrum on election day, and went a bit mad in the process. John, what are you doing to my car? What have we done? Two things were pretty constant. However low trust in politics was before the referendum, it's worse now. Brexit party or no Brexit party. I don't believe Farage for one minute he's for the working people. And no one likes the media either. Every time you switch on the telly, it's Nigel Farage. Yeah, I agree, I agree. That's media driven, with respect to you guys. In fact, no one seems to trust anything anymore. We don't know where we are. Feels good though. This is the sort of place where vox pops could be. What have we got here? Blair Parade! I'm liking it! Can I talk to you for a minute? I ain't got time. Come one, one quick question. What? Are you going to vote today? No. You're not? No. Wow! Blair Parade. - Blair Parade. What do you think of the state of the country? Last question. It's not very good, is it? So why don't you vote then? They will do what they want to do anyway. Not this time, maybe. Yeah, right … They are corrupt, got to go. All the bankers, mate, all the top bankers, the Rothschilds and all them lot mate The politicians, they're all under their cuff now, They all give them money. The entrails of this modern internet politics are everywhere, aren't they? Everyone is a conspiracy theorist now. Which is why, in retrospect, holding a referendum just as technology completely changed the way millions of people thought about politics was always going to turn everything on its head. Do you know what it is? The beauty of representative democracy and I include myself in this, right ... Is you don't have to have a detailed opinion about fuck all you can vote on the basis of whatever you like and it just goes in a big mincing machine, and out comes the government … If you don't want them you can vote them out. The idea that everybody's got to be an expert, it's ridiculous. Look at that lorry mate Why, what's wrong with it? It's on zigzags and he knows that. They ought to take your license away He just blocked someone in. So, have you voted yet? Yes. I'm going now, mate. And who are you going to vote for? Have a guess. Brexit party? Yeah. Why do I need to be in Europe? You give me an answer to that. Well, because it's a series of trading arrangements. How did we trade it before? Different world then, no? Different world? Yeah, it's a different world now. What needs to change about the country to make you feel better about all of this? You don't want it on there ... Go on. Have you been up Swindon town? No, go on. Well, I will tell you what, on a hot day like today. When I go to town ... it feels like I've already gone on holiday, and you know what that means. They are not the people who do all the work? Keep the place ticking over? Who's not all the people who…? Well, the immigrants you're talking about. You're trying to put words into my mouth. What I am going to say is, look at our town, mate, Primark's all we've got here, Primarks and a charity shop, look at me. Right? Primarks and a charity shop. These old jeans. I am not a Primark or a charity shop shopper. I worked hard. There's a lot that's going on for my age to be truthfully honest, like, not many of my friends my age vote or to be truthfully honest, so, it's one of these things that I try to get information relevant to it but I don't know… What if I said though that by not participating you lose to people like the gentleman we've just met. Who's that? Who thinks Swindon isn't Britain anymore, doesn't want immigration and he's going down there to vote for the Brexit party. OK. And you and your friends aren't really engaging on politics and therefore, he's winning. I know, I can see why you're saying that. I am more concerned for what my daughter and my kids growing up and what it's going to be like for them, to be truthfully honest… I don't know, I really don't know. But I literally need to go. Go, go. Who did you vote for just now? Where is this going? On the Guardian's website. Right. Put it this way, democracy is broken. Go on. That's it. Work out from there. It's the Saturday before the Peterborough byelection. Activists have come from all over this part of England and beyond, to help Labour get their vote out. We need a Labour government. How do you feel about the state of the country, right now? It's dying. The far right is on the rise, racism is almost as bad as it was on the 70s. Thanks to all of the constituencies that are here today. and of course the danger is if I start mentioning them I'll leave somebody out, and be told off forever more, but I'm used to that kind of problem with the mainstream media. And I don't care! The one-trick pony Farage is in town today. What does he know about education, what does he know about police cuts? What does he know about the pain of trying to survive on universal credit? He's not talking about Brexit. The B word is unmentioned. We're going to go because we have stuff to do. Can we follow you around? Sorry to disturb you … She's voting Labour. Can you tell me what you think about Brexit? Is this your business? It's my aunty's. So you're from a Portuguese family. I am. But were you born in Peterborough? I've been here for 20 years. How do you feel about the state of the country right now? Brexit and all that… Shit. Sorry, I don't know if I am allowed to use that, but yes, it is, it's really bad. I work at Pizza Hut in town, and we are all foreigners. And we get quite a lot of, you know, abusive … And we've noticed it more since Brexit. Like you know, that we're worthless, really. Nigel Farage, I've just tried to have a bet on him He's 200-1 for the next prime minister and I'm going to have £10 on him. Do you mean that's a good or bad thing if he was the prime minister? I think it would be a good thing. But what's the point if it's all corrupted? They listen to the English people, they don't listen to the foreigners. We've got no say here. It's called democracy It's corruption, really, it really is. Well with democracy we should be allowed to vote for the Brexit as well because we pay the taxes. It's amazing how for Brexit only the older generation voted and not the younger generation. If you think about it, it's the younger generation that's going to be here, not the older generation. See, you're judging me already. God, but the atmosphere has got worse in Peterborough ... you say. Are you canvassing for the Conservative … Oh, no, you're Brexit party people. Only the Brexit party can bring about the change in politics that Peterborough desperately needs. Well, I was into Ukip but that relationship ended. But I've got from left to right, you see. I stood for Labour in West ward here. I did. - Isn't politics weird these days? It was a question of democracy and sovereignty. What Nigel said is that he's going to bring direct democracy, like the Five Star Movement, his aim is to make the Brexit party like the Five Star Movement in Italy, which has direct democracy, where members vote on the policies electronically. God, what a funny old state the country is in, eh? That he wants direct democracy. Beppe Grillo. Well, you better bring back hanging then, that's the thing. See, what I think this is all about is something we've only just started to understand, you know, it's really about what the internet does to politics. Because everywhere is open to everything. Who would have though that we would meet people in with a shout of getting an MP who go on about Beppe Grillo's direct democracy. You know, people who are sensibly on the right of politics who support Julian Assange ... And then Corbyn comes out and says … makes reference to the mainstream media. And it's sort of out of anyone's control. And it's still going. And the crowd here is different. It's more diverse, there's more women, there's more young people… Probably shows you that the Brexit party is spreading. Well I think its the realignment of politics, isn't it? Left and right is in the past. This is about a call for people to try and you know, reconnect with you know, where power is actually… Do you feel like that yourself? Yeah. Thursday, in Peterborough, is democracy day!

This Program Project is designed to provide funds for four projects and one core facility. The studies of the four projects will focus on the intra- and extra-cellular signals which determine the fate of lymphocytes at various stages of their life history. Particular attention will be paid to the factors which affect whether lymphocytes live or die, since the phenomena which control the proliferation and differentiation versus tolerance of lymphocytes are absolutely crucial to the health of the animal. The investigators on the first project have developed a method for isolation of very early lymphocyte progenitors. They will use these cells to find out which transcription factors they express, and how these transcription factors may affect cell development. The functions of these cells and their descendants will also be studied. The studies of the second project will deal with the effect of antigen valency on the fate of lymphocytes. The third project will concentrate on the properties of memory T cells and will study the properties which distinguish these cells from other types of T cells. The investigatory on the last project have discovered that the fate of antigen activated T cells in animals is affected by inflammatory processes. Experiments will be done to find out why antigen- activated T cells die in animals, and how inflammation prevents this death.

In a network environment, a packet needs to be forwarded from a source node to a destination node along a forwarding path, so that a data packet is forwarded, and data is transmitted. The source node is also referred to as an ingress node (Ingress Node), and the destination node is also referred to as an egress node (Egress Node). For a network environment that supports multiprotocol label switching (MPLS), different mechanisms may be selected to forward packets, such as an Internet Protocol (IP) routing mechanism, an MPLS mechanism, and a segment routing (SR) mechanism. In packet forwarding mechanisms such as the MPLS mechanism and the segment routing mechanism, the forwarding path is also referred to as a label switched path (LSP). In a process of forwarding a packet in a network, some service processing needs to be performed on the packet sometimes. For example, when a forwarding node on a forwarding path of the packet has multiple links for selection, to implement load balance on the forwarding node, the forwarding node needs to select, according to a load status of each link, a link to forward the packet. In the prior art, for a forwarding equivalence class (FEC), to perform service processing on a packet corresponding to the FEC in a forwarding process of the packet, some forwarding nodes on a forwarding path of the FEC need to be statically configured, so that these forwarding nodes can process, in a statically configured service processing manner, the packet corresponding to the FEC. However, because there are a large quantity of FECs in the network environment, and a service processing manner of each FEC needs to be configured for different forwarding nodes, a large quantity of forwarding nodes in the network need to be statically configured. Consequently, work of configuring and maintaining service processing for the network environment is extremely complex, and it is difficult to flexibly implement various service processing in the network environment.

Psychological study of cleft palate children with or without cleft lip by kinetic family drawing. To clarify how cleft palate children with or without cleft lip perceive their family, we applied the Kinetic Family Drawing (KFD) technique to 60 cleft palate children (with or without cleft lip). The children were aged 7-9 years (in the 1-3 grade of elementary school) and attended the Department of Oral Surgery, Nagoya University Hospital, between 1990 and 1997. Controls consisted of 100 normal elementary school children of the same age. Major findings were: (1) Compared with normal children, cleft lip and palate boys and cleft palate only girls drew their self-images significantly more often in region D (lower right) and in region A (upper left), respectively. (2) Cleft palate children with or without cleft lip felt anxiety and fear toward their family, rarely viewing their homes as a restful place; this suggested insecurity. Uniquely dynamic relations were also suggested in their homes. (3) Cleft palate children with or without cleft lip often perceived their father or mother as persons easily acceptable in society. Rather remote psychological distance between parents and cleft palate children with or without cleft lip was suggested.

This invention relates generally to a heat actuated fuse and to an apparatus which incorporates such a fuse for protecting electrical circuitry. The invention is particularly useful for interrupting current flow to thick film circuits and components. A heat actuated fuse has an important advantage over the more common current actuated fuse. Although both types of fuses ultimately open at a predetermined temperature, a heat actuated fuse can be positioned such that it responds directly to the temperature of a protected component or circuit, and temperature is often a better indicator of imminent failure than current. Examples of known heat actuated fuses are described in Great Britain Patent 2,145,295A and U.S. Pat. Nos. 4,533,896, 5,084,691, and 5,097,247. Great Britain Patent 2,145,295A discloses a thermal fuse disposed on a substrate nearby a resistor, which is also disposed on the substrate. The fuse includes a pair of electrodes defining a gap between them, a gold fuse link extending across the gap to electrically interconnect the electrodes, and a film of solder overlying the gold fuse link and overlapping at least one of the electrodes. When the temperature of the substrate exceeds the melting point of the solder film, the solder is intended to melt, dissolve the gold fuse link, and then retreat from the gap with the dissolved gold to sever the electrical connection between the electrodes. This fuse is relatively simple to manufacture, but its reliability depends on thorough dissolution of the gold fuse link by the process of leaching. This is a gradual process which begins after the film of solder melts. The gold fuse link then dissolves and is attracted to tin in the solder. The speed of opening of this fuse is relatively slow, and the solder material is limited to a composition containing tin or whatever material will effectively leach the gold or other metal chosen for the fuse link. U.S. Pat. No. 4,533,86 discloses a fuse for protecting thick film devices deposited on a substrate. The fuse includes two terminal clocks, each including a hole, which are mounted to the substrate in close proximity to each other and with the holes aligned. An electrically conductive fusible link (e.g., solder) is suspended across a space between the terminal blocks and extends into the holes to complete an electrical circuit. The holes are larger than necessary to accept the fusible link so that, when the fusible link melts because of excessive heat, molten material from the fusible link will be drawn into the holes. Manufacture of this fuse is a complicated and labor intensive process. Manufacture requires boring of holes in the terminal blocks, coating the inner surfaces of the holes and the end surfaces of the terminal blocks with solder, assembling the blocks and fusible link, and then positioning and soldering the assembled fuse onto electrodes provided on the substrate. U.S. Pat. No. 5,084,691 discloses a thermal fuse comprising a pair of silver conductive pads and a solderable and/or meltable electrically conductive bar extending between the conductive pads. When a conductive bar is applied between the conductive pads, a solder mass structure is applied to the conductive pads, a solder paste is applied through a stencil, and the solder is then heated to provide a connection to the conductive pads. In alternate cases, a solder preform is applied as the fuse element. In this case, the ends of the solder preform are soldered directly to the conductor pads, without the use of a layer of solder paste on the electrodes. Again, the reliability of this fuse substantially depends on the dissolution of the conductive pads by the process of leaching of the silver material. This is a gradual process which begins only after the fuse is activated. The silver in the pads dissolves to increase the gap when the fuse is activated. The speed of opening of this fuse, therefore, is relatively slow. Furthermore, both the solder material and conductive pad materials are limited to certain defined compositions. U.S. Pat. No. 5,097,247 discloses an arrangement of materials which function as a fuse and can be deposited on an electrically insulating substrate, using standard printed circuit fabrication techniques. First and second electrodes are disposed on the substrate, defining a gap therebetween. A layer of first solder paste material, having a melting temperature higher than the actuation temperature of the fuse is disposed on at least one of the electrodes. A conductive link disposed on at least a portion of each electrode and on the substrate extends across the gap to provide an electrical connection between the electrodes. The conductive link is comprised of a second solder paste material which has a melting temperature substantially corresponding to the actuation temperature of the fuse. The melting temperature of the second solder paste, however, necessitates an inert, nitrogen or otherwise non-oxidizing atmosphere during manufacture. Depending upon the circuit board to which the fuse is attached and how the board is processed, the paste may reflow and inadvertently open the fuse. Accordingly, there are a number of problems and drawbacks to the present technology. There is a need for a fuse and/or a method of manufacture to meet the requirements described above, as well as others known to those skilled in the art. It is an object of the invention to provide a heat actuated fuse which opens reliably and quickly, but not at process temperatures. It is another object of the invention to provide such a fuse which can be manufactured simply to open within a wide range of temperatures. It is yet another object of the invention top provide apparatus incorporating one or more of such fuses for protecting circuitry including one or more electrical elements. It can also be an object of the present invention to provide a thermal fuse using a solder paste to tin an underlying metal pattern and/or to control the dimensional coverage of the paste and permit further screen printing. It can also be an object of this invention to provide a thermal fuse prepared using a solder paste and a solder portion and/or chip using standard and/or modified thick film high bred printing technology. It can also be an object of the present invention to provide a thermal fuse and/or method of preparing the same, such that circuit density is increased. It can also be an object of the present invention to provide a thermal fuse and/or method of preparing the same, such that the thermal characteristics of the fuse are improved and the solder contact with the substrate is enhanced. It can also be an object of the present invention to provide a thermal fuse having a preformed solder portion. It can also be an object of the present invention to provide a method for preparing a thermal fuse without manual attachment of a solder wire and/or without a fluxing operation. It can also be an object of the present invention to provide a method for preparing a thermal fuse using a removable solder to bond a second solder portion and/or chip to a substrate. It will be understood by those skilled in the art that one or more aspects of this invention can meet certain objectives, while one or more other aspects can meet certain other objectives. Each objective may not apply equally, in all instances, to every aspect of the present invention. In this regard, the aforementioned objectsxe2x80x94as well as those aspects and features which followxe2x80x94can be viewed in the alternative with respect to any one aspect of the present invention. Other objects, features and advantages of the present invention will be apparent from this summary and will be readily apparent to those skilled in the art having knowledge of thermal fuse and thick film technology. Other objects, features, benefits and advantages will be apparent from the above as taken into conjunction with the accompanying examples, figures, tables, data and all reasonable inferences to be drawn therefrom. In accordance with the invention, a heat actuated fuse for opening at a predetermined temperature comprises an arrangement of materials which can be deposited on an electrically insulating substrate by commonly used printed circuit fabrication techniques. First and second electrodes of electrically conductive material are disposed on the substrate in a spaced relationship to define a gap between the electrodes. A layer of a first solder material is disposed on at least one of the electrodes. A conductive solder portion and/or chip is disposed on at least a portion of each electrode and on the substrate and extends across the gap to provide an electrical connection between the electrodes. The conductive portion/chip comprises a predetermined preformed quantity of a non-paste solder material preferably comprising a flux core solder material, which is in contact with the first solder layers on the electrodes. In alternate applications, a second attachment layer of solder can also be used to attach the conductive solder portion and/or chip to the first layer of solder. Because different solder materials having a large range of respective melting temperatures are readily available, the fuse can be constructed to open at any temperature within a correspondingly large range. The melting temperature of the conductive portion/chip corresponds to the actuation temperature of the fuse. In some applications, the melting temperature of the first layer and optional second layer of solder material used in constructing the thermal fuse are the same or substantially the same as the actuation temperature of the fuse. In alternate applications, the first and optional second layers of solder can have melting temperatures lower than or greater than the actuation temperature of the fuse. A quantity of flux-containing material can be disposed in contact with the conductive solder portion/chip to effect a rapid and reliable flow of the conducting portion/chip to the first and second electrodes, when the fuse is heated to its actuation temperature. As noted above, however, the conductive solder portion and/or chip can comprise a flux core material. When material of this type is used, the amount of external flux used can be reduced or the external flux can be eliminated. In another embodiment of the invention, a resistive device is disposed proximate the fuse for effecting heating of the fuse in response to an electrical current passed through the device. Various advantages can be achieved by utilizing such means, independent of the protected circuit element(s), for heating the fuse. For example, by electrically connecting and physically disposing the resistive device such that it is subjected to the same electrical and environmental conditions as the circuitry protected by the fuse, freedom is achieved in the placement of the circuit element(s). Also, types of circuit elements which cannot, without destruction, produce sufficient heat to melt the fusible portion/chip may be protected. The non-paste solder portion/chip of this invention precludes the need for an inert, nitrogen or otherwise non-oxidizing atmosphere during manufacture. The higher melting point associated with such a solder material can prevent opening the fuse during reflow of the circuit board associated therewith.

American plastic surgery and global health: a brief history. Access to essential surgical care in resource-poor settings is gaining recognition as a major component of international public health efforts. As evidence is mounting about the burden of surgically treatable disease in low- and middle-income countries, so too is the evidence for the significant need for plastic surgery treatment of disease rising in these areas. American plastic surgery has a long history with international surgical efforts in resource-poor regions around the world. Early experiences were not formalized until after World War II, when a foundation partnership provided a venue for interested plastic surgeons to volunteer. These efforts progressed and advanced throughout the 1960s-1970s, but were ultimately devastated by the Vietnam War. Subsequent international plastic surgical experiences by American surgeons over the last 40 years have been largely through several nongovernmental organizations. American plastic surgical involvement in global surgery has changed significantly over the last 70 years. Although quality care is being delivered to resource-poor regions around the world, many of the challenges of regionally appropriate, sustainable care persist today.

Depression imposes a very high societal burden in terms of cost, morbidity, suffering, and mortality. It is the leading cause of disability in the Unted States and the fourth leading cause worldwide. Current methods of treatment are insufficient to combat such a widespread health problem. Therefore, addressing this mental health epidemic requires significant changes in intervention strategies. A growing body of research is examining the use of behavioral intervention technologies (BITs), such as mobile phones to deliver behavioral and mental health interventions. The delivery of interventions via mobile phones offers the potential to provide a near continuous connection between a care system and the patient. However, currently available mobile applications (apps) for depression lack evidence regarding their efficacy. App stores currently offer apps for depression that are designed based on cognitive therapy (CT) interventions, some with behavioral activation (BA), some with mood monitoring only, and many with no discernable psychological approach. Even when based on psychological theory, there is no evidence that the translation of these theories, developed for face- to-face treatment, work the same way for people with depression when delivered through an app. Given the quickly evolving nature of mobile apps, conducting research on every available app will never be possible, nor very useful. The proposed research plan takes an innovative approach to investigating BITs for depression by incorporating principles from psychology, engineering, and design to examine two primary psychological principles, CT and BA, delivered by mobile apps. The project will include two stages. First, the most usable elements of existing apps will be identified to create two apps, one using CT and the other BA, targeting depressive symptoms. This usability process will use a clear, model-driven approach to identify the most usable and useful characteristics for three app elements: information delivery, tools, and visual feedback. Following usability testing and improvements, the two apps will be subjected to a small comparative trial. Secondary aims will include an examination of usage of the apps, defined as how many times the apps are opened on the mobile devices. Results will provide information that can be broadly used by developers of apps for depression and may also have implications for apps aimed at treating other mental health disorders.

"♪♪" "Tracy?" "Hey, sorry i'm late." "It took me 40 minutes to park, And then the store was a madhouse." "Tracy?" "♪♪" "Hey." "♪♪" "Why aren't you cooking?" "Scott and meryl will be here in an hour." "I was late." "Late?" "There's only one stripe." "That means you're not pregnant." "Don't look so happy." "I'm not." "I" "Look, you were the one who said that" "You didn't want to have a baby until we were able to move." "Ok." "So, let's go." "let's get out of here." "Let's go somewhere where we can have some space" "And, you know, see some trees." "You know, that'd be great, but how are we going to do that?" "All i know is that i want to have a baby," "And i don't want to raise it here." "The suburbs." "are you sure?" " No." " uh, no." "We're just going to check it out." "What about the commons?" "Oh, don't." "Don't put them through that." "Why?" "What is it?" "A couple of years ago, we started looking," "Found this place-- fell in love with it." "A bunch of uptight snobs." "Incredible schools, the best sports programs," "And the homes are amazing." "So what happened?" "They loved us." "and scott thinks i'm crazy," "But i swear they lost interest" "Whene started blabbing that we didn't want to have a second child." "Excuse me for being honest, you know?" "Go ahead and check it out." "I wouldn't live there now if you paid me." "The commons, huh?" "I have a really good feeling?" "Even after what scott and meryl said?" "It wasn't right for them." "That does not mean it won't be right for us." "Maybe." "I just can't get used to living in the suburbs." "Keep an open mind." "You may end up loving it." "This must be it." "Now what?" "Is there a doorbell or something?" "Ok. that's weird." "I guess that means we go in." "Sync:" "FRS@¹âÏË" "fear itself S01 ep07" "The commons was created on the basis of a growing need For family values." "Now, i'm sure you grew up in a neighborhood like we did" "Where neighbors look out for one other" "And crime is something that happens in another part of town." "These ideals are the cornerstone Of what we're all about." "That sounds amazing." "So why'd the previous owners leave?" "business." "he was transferred." "Here we are." "come on." "Hey." "Don't get your heart set on this, ok?" "Come on." "Did i mention, the previous owners Couldn't take their furnishings," "So if you like it, comes with the house." "Take your time." " explore." " Thanks." "Look. look at this kitchen." "Look at this kitchen!" "Bet you the closet space is just amazing!" "There's fireplace!" "Look!" "Come on." "Sit." "Sit." "We do not belong here." "Yeah." "That's right." "Ok." "I'm going to call you later." "They're coming back." "Well, what did you think?" "I'm sorry, but i think we've wasted your time." "we were just wondering if maybe there was something a little bit smaller." "I'm afraid this is the only home available." "You guys are, what, 25?" "26?" "No kids, but you want to start a family someday?" "Yeah, that's why we're here." "But it's-- this is just too much." "We've helped a lot of couples buy new homes here," "Couples just like you." "Do me a favor?" "fill out an application." "What have yotsu elgoft to lose?" "Tracy, i'm home." "We did it!" "we got the house!" " ?" " Yes!" "Yes!" "It's going to be so amazing." "It's going to be amazing." "Wait a sec." "These great loans," "Way more house than we could afford anywhere else." "What's the catch?" "Ok, bobby, what are you doing?" "Oh, no, no." "It's ok." "i understand." "Buying your first home is a little scary," "Buyers jumping through hoops And eryone making a quick profit." "We'll make our profit, too." "But buying a house is not about money." "It's about security And comfort and family." "You want a catch, bobby?" "here it is:" "We can't survive without people like you investing in our carom imutsnieltyf." "And that investment is the life you create here." "Now, here's a socioeconomic breakdown of our residents." "When i said this was a planned community, it was an understatement." "We are a finely tuned microcosm" "Based on hundreds of years of research In communal living," "From african tribes to medieval villages To the american suburb." "The commons has thrived for the last 20 years" "Because we know precisely what it takes to make a community work." "And right now, that's you." "Based on 73 separate criteria," "You as a couple meet our needs 97%." "So if we don't do this right now," "What are the chances of us meeting your needs again?" "You're more likely to be struck by lightning" "While holding a winning lottery ticket." "Are you sure this is what you want?" "I want this for us." "Welcome to your new home!" "We're happy to call you neighbor." "thank you!" " Ready?" " yeah!" "Hi!" "Think they'll do this every day?" "Well, here we go." "Listen!" "do you hear that?" "No." "What is it?" "Nothing." " Isn't it great?" " yes." "We did it." "it's our house." "?" "I'm going to go put my thing in." "Ok?" "i'll be right back." "what?" "What are you doing?" "Trying to make a baby with my wife." "Are you sure?" " Yes?" " yeah." "Hello?" " Hey!" " hi!" "Oh, see?" "They did keep the furniture." "Now i'm second-guessing my gift." "Well, they'll prably return it anyway." "Who cares?" " Hi." " hi!" "We're the fabers, your next-door neighbors." "Try to say that after a few martinis." " Stop it." " a mew fartinis." "Stop it!" "Hi, i'm debra, and this smart aleck is phil." "I'm bobby." "this is my wife, tracy." "Hi." "You think we looked that young and cute when we moved in?" "Well, i did." "How long have you guys lived here?" "12 years august." "Worst 12 years of my life." "Philip, stop it!" "They don't know you well enough yet." "Oh, come on, honey, they know i'm just kidding." "I'm not kidding." "Well, bobby, you got a beer?" "no, i don't, sorry." "It's still a little early for us." "Have one of mine." " Come on in." " come on in." "Thank you!" "Hey." "You pay whatever you want" "One of the little perks of the commons." "I'm leaving." "Sit here." "ok." "my goodness." " This place is amazing." " I'm spoiled rotten." "Arlene." "Hi." "I'm tracy." "we just moved in yesterday." "I know." "You getting settled?" "yeah." "I mean, i already feel like i belong." "Any kids?" "You want mine?" "she's house-broken." "I'm joking." "Well, i got to go." "I'm in charge of our subdivision's residents committee," "So i'm going to hit you up to volunteer soon." "Please." "please, do that." " Great." "Bye!" " ok." "Bye." "Ok." "Bye!" "see you tomorrow!" "Wave at the nice lady." "?" "She's beautiful." "Bye!" "I think you've had enough." "My love, there's never enough." "You play golf, bobby?" "it's been years." "When it gets warmer, we'll get you out there." "Hey." "hey." "How's it going?" "You having a good time at the party?" " I'm all right." " yeah?" "But i think i got to make a liquor run." " These people drink a lot." " You can dress it up, but it's rotten and stinking to the core." " Will you please be quiet?" " no, i won't be quiet!" "What, do you want to cut my balls off?" " Will someone stop him?" " They're all just afraid to say anything." "They had no right!" "Don't worry, kids." "Uncle phil's is okey-doke." "Let me help you up." "It's ok, bobby." "We know how to take care of him." "Hi, debra." "oh, sorry." "I just haven't seen you and phil since the party." "How's he doing?" "i thought you knew." "his brother died." "He had tgo take care of it." "Oh, no." "Well, give him our best." "You're so beautiful, sandra." "Hey, isn't that sandra from across the street?" "What is this?" "sandra!" "Oh, god!" " How could you be so stupid?" " ?" " Do you realize what you've done?" " I'm sorry!" "No!" "No!" "Hey, you see that?" "What's going on here?" "♪♪" "?" "In a while." "We're wondering how you're doing over there in yuppie heaven." "Give us a call." "Hi, tracy. it's arlene." "I got you an appointment with my ob." "She's amazing." "I told her all about your problems conceiving, so..." "Call me back!" "Tracy, arlene just left you a message." "Why are you sharing our sex life with your friends?" "Because they're my friends?" "I don't know. they're moms." "They've been through this." "why are you asking me this?" "Because, i don't need their judgment." "We've only been trying for 3 months." "♪♪Un let's just keep it between us, ok♪" "I think you're being a little sensitive." "I'm going for a run." "Oh, wait." "I forgot to tell you that candace called." "You've got a meeting with the resident's group tonight." "Ron and sandra, What we do is arbitrate." "We offer solutions to everyday problems." "It's how villages and tribes have functioned for thousands of years." "And it's what community is all about." "Trust her." "it won't happen again." "Everyone in town saw her." "We can't just ignore it, ron." "That wouldn't be fair to everyone." "Infidelity rips at the very fabric The commons is created from." "What divides a single couple divides us all." "Now, in cases like this," "The offending spouse is sentenced by the partner From a prescribed list." "Ron, do you understand that?" "I choose her punishment." "Hold on." "what are we doing here?" "This is between sandra and ron." "We're not talking about someone who left their garbage cans out." "Why is this any of our business?" "Because we're their neighbors." "And we care." "Make me want to puke!" "Harlot!" " Whore!" " Disgusting!" " just a whore!" " Why does she have to stand there?" "She broke a rule, sweetie." "She's in a grown-up time out." "was it worth it?" "Hey, how can you let this happen?" "This is sick." "this is medieval." "It's only for a few hours." "What would you do if you caught your wife screwing around?" "Divorce her?" "Kill her?" "pretend it didn't happen?" "We'd deal with it privately." "They will, too." "But first, she's has to deal With what she's done to the rest of us." "Her neighbors will help her through it." "And it'll strengthen the community." "And i guaran-damn-tee she won't screw around again." "This is how you chose to punish your wife?" "No." "She chose it." "I'm so sorry, sandra." "No!" "Don't interfere. please!" "Bobby, stay out of this!" "Bobby." " Sandra?" " i just wanted to say" "If the community hadn't stepped in when they did," "Our marriage would be over." "Bless you." "And you two keep trying." "Don't give up on that baby." "Thanks." "Tracy?" "I just ran into ron and sandra" "Heather and candace came by." "We like to check in?" "After they've been here a while to see how they're adjusting." "Oh, and we're doing great, aren't we?" "Yeah, great." "It's obvious." "your house is wonderful." " ?" "Pride of ownership." " absolutely." "Ok." "I don't mean to be rude," "But if you want something from me" "You want me to volunteer for another committee" "They're concerned about us." "Because?" "Because we haven't gotten pregnant yet." "There's no need to panic." "It happens to lots of couples." "We just want you to know that we can help." "Oh, we don't want your help." "Our private life is none of your business." "We really are fine." "I know. i just want you To explore every possibility." "We have fertility specialists." "We have donors." "Ok." "You need to leave." "Now." "We truly want to help." "Now, i suggest you take a look at the resident's agreement That you both signed." "We have every right to be concerned." "Your house is lovely." ""child shall be conceived within a period of up to and including, but not to exceed," ""6 months from the first day of residency." ""failure to do so will result In the foreclosure of your property-- "" "♪♪Can they do that♪" "I don't want to leave." "I don't either." "But..." "They're trying to control us." "Tell us when to have a baby?" "C'mon!" "I-- i know, but that's why we're here," "To raise a family in a safe environment." "They made that possible." "Look at their success rate." "It obviously works." "It does!" "i want this for us." "What are we going to do?" "We want to do everything we can to uphold the contract." "But what if we're unable to conceive?" "Oh, well, that's highly unlikely given your combined genetics," "But you would be in default." "You'd lose the house, any equity," "Your credit would be damaged for years." "It would be unpleasant." "What if we had a miscarriage, Or we just wanted to move?" "Sorry, no." "That's all covered in your agreement." "So, basically, we're trapped here," "Expected mate on demand." "No." "You make it sound like it's a zoo." "You're saying that every couple for the last 20 years" "Has spit out babies on your schedule" "And lived happily ever after?" "It's a delicate biosocial balance." "We have singles." "We have couples without children." "We've never asked anyone to conceive" "Who wasn't already planning on doing so." "Now, in the application that you signed," "You stated that you wanted to become pregnant Within 6 months." "I can show you, if don't rember." "That's ok." "We've been doing this a long time." "We're very good at choosing our neighbors." "We have faith in you." "Yeah, i'm looking at this contract." "Why would you sign this?" "Why didn't you call me first?" "Is it legal." "It's a legal document." "It's a ridiculous breach of civil liberties," "But you sign it." "I just want some control." "Move." "I mean, there'd be consequences." "No, we can't." "tracy doesn't want to go." "She doesn't know i'm doing this." "But if we have a baby, we're stuck in this place." "Tell me what you want me to do." "Help me find the previous owners." "Run a credit check." "get a number." "They got out." "i want to know how." "I can't believe we may lose this." "All i want to do is raise a family here." "Don't give up." "it's all worth it." "Once you feel your baby growing inside of you," "You know you're not just living for yourself anymore." "Your priorities change completely." "I love my house, but what's important," "Why we're really here, is for our kids." "And unless your kid's a complete freak," "They'll be offered the best schools, the highest-paying jobs." "It's an unwritten rule of the commons." "We're not just neighbors in here." "We're neighbors anywhere we go." "20 years of ex-residents" "Highly placed in virtually every sector of government and industry." "Connections from this little neighborhood run scary deep." "Realize how lucky you are to be here." "And girl, do whatever you can to hold onto it." "No." "He's not feeling well." "I just need to ask him a few questions." "I'm sorry about your brother, phil, but i need to know" "What happened to the couple who owned our house?" "Leave him alone, bobby." "This agreement we signed, we didn't realize" "It's insane, and i need to know how that family got out." "Phil." "what happened to you?" "Go home." "we can't help you." "He disappeared." "What do you mean he disappeared?" "All his credit accounts, his bank accounts, closed." "It's like your previous owner fell off the planet." "What do you think that means?" "Eithere's dead, or he's pretending to be." "Why would he do that?" "What the hell's going on over there, bobby?" "We're worried about you two." "We're ok." "Don't let meryl say anything to tracy." "Thanks, scott." "Hey." "hey." "What's that?" "I got you something." " Can i open it?" " Yes.?" "I got 2 stripes." "Bobby, i love you so much." "We did it." "Yeah." "I mean, i want to, you know, get officially checked out by the ob," "But arlene, she said that these ings are pretty much foolproof." " So, i think that we're ok." " You told her before you told me?" "I know." "I just didn't want to tell you over the phone," "And i had to-- no." "Hey, listen." "Don't get mad, ok?" "This is our dream, and it's happening," "So let's just enjoy it, ok?" "you know what?" "I think it's my parents calling." "Hello?" "I know!" "It's so exciting, isn't it?" "Yeah. he just can't wait." "He's-- he's thrilled." "Look." "Yeah." "Oh-- check it out." "But yeah. this is, um..." "That's a photo of our baby." "You're so beautiful." "I think i'm going to like this pregnancy thing." " ?" "You know so?" " yeah." "No." "Sandra!" "What" "She jumped in front of the car!" "I saw it." "She was definitely drunk." "No, no, no!" "she was terrified." "She wanted help." "Someone was chasing her." " Did you see?" "She was" " No." "She jumped in front of the car." "It was suicide." "we all saw it." " These people are insane." " Oh, my god." "What do you mean that thedisappeared?" "'Cause candace, she said-- she said that they" "Candace lied, ok?" "Something is very wrong here." "Will you just please, stop?" "please, stop?" "Because you're scaring me." "You should be scared because" "'Cause why..." "Come on.?" "Phil, debra!" "open up!" " Hello?" " Tell us what's happening." "We're scared. ?" "out of this?" "We have a daughter." "leave us alone!" "Is that what they do?" "they go after your family?" "Phil-- phil, what happened to your brother?" "What did they do to you?" "I'm sorry, honey." "Everyone needs to find out on their own." "Actually, it's kind of liberating." "We're all in this together." "did i tell you about gracie's report card?" "She did great." "I'm so proud of her." "The teachers want to put her into the advanced learning classes." "She's already reading at the fourth grade level." "And she's the best speller in the class." "Bobby, get the hell out of there." "No." "I have to get tracy and the baby safe first" "Hide them, get them new identities." "They'll come after us." "they won't stop." "They own us." "How can we help?" "I have an idea." "We're going to need meryl." "We should call your doctor." "Oh, no, no." "It's probably just heartburn." "I just need to rest." "I promised arlene i'd help her organize tomorrow." "I'm so excited about this fundraiser." "The school library's going to throw a dinner for all the volunteers." "We need as many people to contribute as possible." "I think we need about 10 volunteers to work the phones." "Tracy, you look pale." "Do you want something?" "yeah." "Maybe i should just get some water." "Well, i'll take care of the emailing," "And make sureteod." "?" "the baby!" " Someone call 911!" " No, no, no. just, please" "Just call bobby. please.." "Just call bobby." "One of us will go with you." "No, that's ok." "I'll call you just as soon as i can." "Ok, meryl." "ok." "How you doing, meryl?" "nervous." "?" "Here we go." "If the tv cuts to you, just cover up, ok?" "We can't let them recognize you." "Hello?" "Hi, arlene." "Yeah, no, tracy and the baby are fine." "She's just confined to the bed for a little while." "No, no, no." "no visitors." "Thanks." "Bye." "Just stay covered." "Thank you." "thanks." "I'll give tracy your kind words." "Just let us know." "They're suspicious." "We've been on tv for 2 days straight." "Why hasn't scott called?" "Tracy and her parents should be reaching the cabin at any time." "They'll let scott know, and as soon as he calls us," "We're out of here." "Maybe that's him." "Hey, scott." "Hey." "she's better." "No, no, no." "no visitors tonight." "Ok. we'll give you a call." "Tonight." "Let's go." "?" "Bobby." "Who the hell are you?" "where's your wife?" "Run!" "get out of here!" "It'll be ok, meryl." " No meryl, it won't." " bobby!" "And you can thank your friend bobby for that." "Where's tracy?" "♪♪" "Where is she?" "You can kill me, but tracy and the baby are safe." "And everyone will know what happens here." "Kill you?" "Why would we kill you?" "You're our neighbor." "We just want you to be happy." "But your family and friends," "They may have a little accident, like meryl." "What is that?" "Something to help you talk." "Don't worry, bobby." "We're your friends." "Welcome back." "You've had quite the nap." "You must feel horrible." "i'm sorry." " Are you up for a ride?" " Where?" "♪♪" "To see tracy." "she came back." "You're lying." "she wouldn't." "Where's bobby?" "I'm going to knock some sense..." " ...into that son of a bitch." " Will somebody get him out of here?" "Come on, phil." "bobby's ok now." "What, he's ok?" "Bobby's staying?" "Bobby's staying!" "Oh, bobby, you're staying." "That's so great." "That's great that you're staying." "That's so great." "This is for you." "Ron, will you do something about this?" "What are you doing?" "Oh, my god!" "Candace!" "run!" " Hey!" " run!" "Bobby?" "Bobby!" "♪♪" "Come on back!" "Bobby!" "Bobby!" "Bobby?" "Bobby!" "Bobby?" "Bobby?" "Bobby!" "It's me!" "Hey, bobby!" " Bobby?" " bobby, it's scott!" "Tracy!" " bobby!" " What are you doing?" "you were safe." "I had to come back for you." "♪♪" "They've got meryl." "we have to get out of here." "No." "Bobby." "Bobby." "i love you so much." "I am doing this for us." "?" "Scott." " ?" " It's an amazing house, bobby." "The schools are incredible." "We're going to be neighbors." "It's going to be great." "No!" "No!" "No, no!" "No!" "No!" "No!" "?" "Stop!" "It really is a lovely community." "Everybody watches out for each other." "and if you're planning on having kids," "There's no better place to raise a family." "That's why we're here." "he's adorable." "He's a handful." "So, i'm looking forward to meeting your husband." "Yeah. he's working right now." "there he is." "So why'd the previous owners leave?" "Business." "he was transferred." "We feel so fortunate to be here." "It really is a wonderful community." "Bye." "♪♪"

Zippers have a long and rich history, from their invention over 150 years ago, to the latest shapes, configurations and materials, where development continues today. The market for these fasteners has developed so that zippers are commonly sold in sets: left and right tapes with interlocking teeth, and one or more sliders accurately sized and constructed of compatible materials to assure an acceptably long life of the set. However, between the wide range of sizes, shapes, configurations and colors, and the typically lengthy service life of a zipper, it is often difficult or impossible to find suitable replacement parts for a broken zipper—more often, one must disassemble the garment or item and replace all the parts of the broken zipper when any part fails. This is inconvenient, and the repair cost often exceeds the value of the remaining service life of the item. What is needed is a universal, or one-size-fits-many, replacement zipper slider. This could extend the useful life of many items with zippers, and when the item finally fails from some other cause, the replacement slider can be recovered and used to repair something else. Some replacement sliders are known (see, for example, U.S. Pat. No. 7,313,847, co-invented by the present applicant) but new designs that improve the function or manufacturability of these repair devices may be of value in this field.

Electronic circuits typically include a number of components. These components can be discrete devices, or provided as part of integrated circuits. Whether provided as discrete devices or integrated circuits, multiple electronic components are often interconnected to one another by placing those components on a common printed circuit board. In addition to providing a structural member to which components can be attached, a printed circuit board typically provides traces on one or more layers to conduct power and signals to and between attached components. When used in connection with implementing complex circuits, the design of the individual circuit boards can also become quite complex. In addition, where a large number of components are to be interconnected to a printed circuit board, the area of the board can become quite large, and a relatively large number of layers may be required to provide the necessary connective traces. In addition to providing conductive traces, certain electronic components can be integrated directly into a printed circuit board. One consideration in the design of electronic circuits is the size of those circuits. In particular, by making devices smaller, certain performance parameters can be improved, and the device can be easier to package and transport. Also, it can be desirable to maintain electronic circuitry within size limits that are defined by certain components of a device implemented using the electronic circuitry or a component of that circuitry. One example of electronic circuitry that can be quite complex, but that is desirably deployed within a relatively small area, is a phased array antenna. In a phased array antenna, multiple antenna elements or radiators are deployed across a surface. The size of each antenna element is generally determined by the intended operating frequency or frequencies of the antenna. Furthermore, as more antenna elements are provided, the antenna beam can be more narrowly focused and directed by applying selected phase delays to the signal comprising the beam that is delivered to (or received from) each of the antenna elements. That is, by varying the delay of a signal, the corresponding beam can be scanned along one dimension for a one dimensional array of antenna elements and along two dimensions for a two dimensional array of elements. In addition, the maximum scanning angle that can be provided by an antenna will increase as the space between antenna elements is decreased. Accordingly, the radiator or antenna elements of a phased array antenna generally occupy an area that is defined by the size of the individual antenna elements, the number of antenna elements, and the spacing between antenna elements. Within the area defined by the antenna elements of a phased array antenna, on a side of a circuit board opposite the side on which the antenna elements are formed, circuits have been developed that allow the phase delay of two separate beams to be controlled. However, where a phased array antenna is intended for simultaneous communications with or tracking of a larger number of targets, it is desirable to increase the number of beams that can be individually controlled. This has been difficult or impossible to achieve using conventional techniques in connection with the circuit board on which the antenna elements are formed. In addition, because higher frequencies generally require a smaller antenna element, it has been especially difficult to provide supporting circuitry for systems designed to operate at high frequencies. In order to provide the area necessary for complex beam forming networks, additional circuit boards containing components of the beam forming network can be placed behind the board on which the antenna elements are formed, for example on circuit boards arranged perpendicular to the antenna element boards. That is, the space available for circuitry can be expanded into three dimensions. Although such systems provide a place for the circuitry required to provide a number of steered beams, they do not address issues of design difficulty and ease of expansion. In particular, each board or other unit of circuitry typically includes elements that are unique to that board.

[Changes in the lipid-accumulating cells of the liver during experimental hypervitaminosis A]. Changes of the fat-storing cells (FSC) in the liver have been studied after oil solution of vitamin A have been injected to intact rats, when Kupffer's cells have been blocked with colloid silver and stimulated with prodigiosan. During these experiments (on the 4th, 7th, 14th days) the amount of FSC does not change, and their size increases. The blockade of Kupffer's cells does not influence the dynamics of the FSC changes, and their stimulation contributes to lipid accumulation in their cytoplasm and to earlier revealing of these elements (on the 2d day of the experiment). In parallel with increasing size of FSC, fatty infiltration of hepatocytes disappears and reticular fibers accumulate in the perisinusoid space. Participation of FSC in lipid metabolism and in synthesis of the III type collagen is proved, as well as existence of intercellular interactions of these elements with endotheliocytes, Kupffer's cells and hepatocytes.

One of the methods currently used for the in-flight refueling of aircraft comprises the use of a boom provided with an internal section with capacity for telescopic extension via which aircraft fuel is transferred by means of an internal line from the tanker aircraft to the receiving aircraft. The boom is connected to the tanker aircraft by means of a hinged system provided with two degrees of freedom and is equipped with a set of movable aerodynamic surfaces or fins which, by means of independent variations of the incidence of each of them relative to the incident air flow, enables the operator of the system to position the boom in the conditions of desired attitude. The limit of the attitude envelope attainable depends on the maximum capacity of said fins for generating forces that make it possible to balance the set of aerodynamic, inertial and gravitational effects relative to the linkage of the system. Movement of the boom from one position of equilibrium in space to another is effected by using these fins, with their initial and final positions corresponding to those that balance the boom in both spatial conditions. Said movement is a movement of rotation about each of the two axes defined by the two degrees of freedom of the linkage (elevation-roll or elevation-azimuth). The dynamic characteristics of said system correspond to a modal description characterized by a very low damping ratio. Consequently this movement generated by a direct change of fins from that corresponding to equilibrium in one spatial position to another spatial position involves an oscillatory movement of the boom with very little damping. To accomplish the precise and predictable operation of tracking of the refueling socket or receiver of the receiving aircraft, without running the risk of causing an impact between the recipient and the boom, it is necessary for the movement of the latter to be sufficiently damped. For achieving this aim, the prior art employs electrical control systems (fly-by-wire), with functions for increasing stability and control, in such a way that the dynamics of movement, by means of said control system, has the desired characteristics for performing the task of tracking the receiver. An electrical flight control system comprises: Elements for measuring movement and/or position of the platform to be controlled, called sensors. A control element in the operator's cabin, generally a joystick, for controlling the movements required by the operator. Actuating elements that generate the movement of the control elements of the platform, in this case the aerodynamic surfaces. An on-board computer or calculating system with on-board software that includes algorithms which, when supplied with the orders generated by the operator, together with the measurements of movement and/or position of the equipment, generate a command for movement of the control elements, via their actuating systems. The algorithms implemented in the on-board computer are directed towards modification of the natural dynamics of the equipment to be controlled as well as provision of other functions such as a manoeuvre or position demand system. In the case of the in-flight refueling boom system, the control algorithms must perform a basic function of increasing the damping of the basic equipment, from a very low value, close to zero, up to a value compatible with a rapid and predictable response without oscillations or exceeding of the final value demanded. This desired response is associated with appropriate operating conditions for performing the task without requiring significant compensation of the dynamics of the equipment by the operator. The increase in damping is achieved by means of a command for movement of the aerodynamic fins so that they generate a load, producing an overall force on the boom that tends to oppose the angular movement of the latter. The damping effect is achieved by means of a fin movement of a magnitude related to the angular velocity (normally a proportional relation) and opposite in direction to this angular movement. The basic characteristics of the refueling system necessitate increased damping of the angular movements defined by both linkages (elevation-roll or elevation-azimuth). Owing to the fact that in the design of the refueling probe the length of the probe predominates, as well as its lowest possible weight, the structural characteristics of the boom are characterized by particular modes with extremely low frequencies. These frequencies are close to the natural frequencies that define the movement of the boom as a rigid solid about the linkage and the frequency of control thereof used by the operator for controlling said movement. These flexible modes are also characterized by a very low damping ratio, exhibiting a very characteristic resonance frequency with a high level of amplification of the response if excited at said natural frequency. The flexible modes of the probe are excited when subjected to external loads, such as the forces generated by the fins in the process for controlling the position of the boom. The excitation through movement of the aerodynamic surfaces has two origins: one due to the change in aerodynamic load on changing its angle of incidence, the other due to the inertial loads caused by rotation about its axis of rotation. In the case of the in-flight refueling boom, the effect of generation of aerodynamic load is dominant. The elements of the flight control system that detect the movement of the boom measure the movement of the section of the boom where the measuring elements are located, detecting both the movement as a rigid solid, the control object thereof, and the movement associated with the flexible vibration of the structure. Therefore the control algorithms are fed with the rigid and elastic movements, which are converted by these algorithms into a demand for movement of the aerodynamic fins. By their movement, these in their turn generate new forces which in addition to acting on the movement of the boom as a rigid solid, once again excite the structural modes. This combination of rigid and elastic movements is fed again to the control system, and a coupling effect is produced. The effect of coupling of the flexible movement of the structure with a control function as a rigid solid is called “structural coupling”. The excitation of the structure through movement of the aerodynamic fins decreases as the frequency increases, owing to the natural attenuation of the actuating system, as well as the intrinsic capacity for generation of aerodynamic force. This effect of feedback of the movement must be such that the resultant dynamics are stable, and must moreover guarantee a margin relative to the condition of instability of the complete system, formed by the equipment to be controlled plus its control system. In the qualification of system airworthiness, minimum stability margins are specified both in the control of the rigid modes, and in the stability of the flexible modes. In the phenomenon of structural coupling, the closeness of the rigid and the flexible control frequencies is critical, therefore the first flexible modes are of low frequency and are relevant to the phenomenon. The dominant flexible mode will be regarded as that having greatest influence on the problem of structural coupling, i.e. by its frequency, by a low damping ratio, by excitation due to the deflection of aerodynamic fins or by its detection by means of the elements for measuring movement or position. A first measure for reducing this phenomenon is to locate the measuring systems in positions that are not altered by the movement due to the flexible modes relevant to the phenomenon, or even to locate the control surfaces at a point of less excitation of the structure. Whereas the location of the elements for measuring movement can at times have some flexibility during design, the positioning of the control surfaces has to satisfy the capacity for control and balancing of the equipment. In any case, positioning of the measuring elements in a position that is not altered by the movement due to the relevant flexible modes is not a robust solution owing to the change of these modes with possible changes in configuration of the equipment, as is the case with the movement of extension of the telescopic tube in the case of the refueling boom. In the case of the boom, the aerodynamic fins must be positioned to be sufficiently remote from the linkage to produce a balancing moment about the linkage by means of a force that is as small as possible. The measuring elements can be located in the sections that interfere as little as possible with the transverse section of the boom, so that the aerodynamic drag does not increase significantly. These can be positioned at the root of the boom and in the section with the fins. The usual techniques for avoiding the phenomenon of structural coupling are based on performing signal filtering, whether those obtained via the measuring systems, and the signals for command of fin movement, in such a way that there is no change in content of the signal with respect to measurement of rigid movement. The negative effect of said filtering is that the more we wish to attenuate the content of the flexible signal at high frequency, the more phase lag is induced in the signal in the range of control frequencies as a rigid solid. This phase lag means that the maximum damping ratio that could be obtained by means of feedback is limited. The greater the phase lag, the lower will be the maximum damping ratio attainable by means of feedback, and therefore the handling qualities that can be achieved will be poorer. In the case of the in-flight refueling probe, the closeness of the flexible frequencies and the control frequencies means that the usual method of filtering cannot be used for simultaneously achieving the objectives of guaranteeing the required stability margins and providing adequate handling characteristics for performing the task of tracking of the receiver. The present invention aims to correct this shortcoming.

Change in career aspirations and job values from study time to working life. The main aim of this paper is to uncover whether the actual career choices and job values of newly qualified nurses are in accordance with the predictions they made at the commencement of their nursing education. A cohort of Norwegian nurse students was followed from the beginning of their education in 1998 through nursing school and 2,years after graduating. Questionnaire data from 221 nursing students at three points in time: 1998, 2001 and 2003 were analysed with frequency distributions and paired samples t-tests. For 140 respondents data from all three points were available. Initially motives like human contact, helping others, job security were important, and 92% had a wish for further education. Career preferences were often midwifery, public heath and nursing practice in high tech areas. Towards the end of the bachelor course (2001), there was more ambiguity in the helping motives. On one hand, the students wanted to be altruistic but on the other hand, they wanted gratitude in return when giving help to patients. Seventy five per cent of the students had plans for further education within a period of about 2 years after graduation. Midwifery, public health work and high tech practice were still preferred. Findings from 2003 indicated only 16% had started or finished further education 2 years after graduation. When appraising future job challenges in 2001 and 2003, there is a decrease in emphasis on the values human contact and part-time work and an increase in emphasis on high salary and job security. During the student period, the bachelor programme was regarded as a basis for further education, but 2 years after graduation only 16% had realized further education. Preferences related to job values regarding a prospective job reveal a decrease in the importance of human contact and an increase in the importance of a high salary and job security from 2001 to 2003.

"Holy shit." "You all right?" " Yeah." " Hershel?" "Let's head back." "Car." "Car." "Get down." "Dave?" "Tony?" "They said over here?" "Yeah." "I'm telling you, man, I heard shots." "I saw roamers, two streets over." "Might be more around here." "It's hot." "We gotta get out of here." "Dave!" "Tony!" "Shut up, idiot!" "You wanna attract them?" "Just stick close." "We're gonna find them." "Dude, he said to stay close." "Tony." " They should've been back by now." " Yeah." "They just got holed up somewhere." "We'll head out first thing in the morning." " Thank you." " Welcome." "Thanks." "Carl, I want you to keep your head up, okay?" "Your old man, he's the toughest son of a..." "No cussing in the house." "Sorry." " Lori, dinner." " She's not in there." "Where is she?" "Carl, when's the last time you saw your mom?" "This afternoon." "She was worried about Rick, asked me to look in on Carl." " She went after them?" " She didn't say that." "Nobody panic." "Gonna be around here somewhere." " Why won't they leave?" " Would you?" "We can't sit here any longer." "Let's head out the back and make a run to the car." " What happened?" " Roamers." "I nailed them." " They disappeared, but their car's still there." " I cleared those buildings." " You guys get this one?" " No." "Me neither." "We're looking for Dave and Tony and no one checks the damn bar?" "What?" "Someone pushed that shut." "There's someone in there." "Yo, is someone in there?" "Yo, if someone's in there, we don't want no trouble." "We're just looking for our friends." "What do we do?" "Bum rush the door?" "No, we don't know how many are there." "Just relax." "We don't want any trouble." "We're just looking for our friends." "If something happened, tell us." "This place is crawling with corpses." "If you can help us not get killed, I'd appreciate it." "Dude, you're bugging." "I'm telling you nobody's in there." "Someone guard the door." "If they're in there, they might know where Dave and Tony are." "They drew on us!" "Dave and Tony in there?" "They alive?" " RICK:" "No." " They killed Dave and Tony." "Come on, man, let's go." "No, I'm not leaving, I'm not telling Jane." "I'm not gonna go back and tell them that Dave and Tony got shot" " by some assholes in a bar." " Your friends drew on us!" "They gave us no choice!" "I'm sure we've all lost enough people, done things we wish we didn't have to, but it's like that now." "You know that!" "So let's just chalk this up to what it was, wrong place, wrong..." "Get outta here!" "Go!" "We can't find Lori." "And the others aren't back yet either." "That dumb bitch must've gone off looking for them." " What?" " Yeah, she asked me to go." "I told her I was done being an errand boy." "And you didn't say anything?" "Don't do this." "Please." "I've already lost my girl." "Yeah, that wasn't my problem neither." " She's not at the barn." " I checked the yards." "Well, where is she?" "She asked Daryl to go into town." "Must've gone herself." "Hey." "Carl." " Did you know about this?" " No." "Look, just, did she take a gun?" "I don't know." "I wouldn't let her go out there alone." "Hey!" "We all know this is not gonna end well!" "There's nothing in it for any of us!" "You guys, just back off, no one else gets hurt!" "Shit!" "Glenn!" "Glenn!" "I'm all right." "I'm all right." "Lori!" "I'll hold them here." "You cover Glenn." "See if you can make it to your car." "Tell him..." "Tell him to pull up back." "We'll run for it, get the hell out of here." "You want me to cover Glenn?" "You missed all that gun training." "It could've come in handy now." "I can shoot." "I just don't like to." "Sorry." "Sorry." "Rick wants you to try for the car." " Try?" " You'll try and succeed." " I'll cover you." " That's a great plan." " What happened?" " He fired." "He must've hit Glenn." "He's behind the dumpster." " Doesn't look like he's moving." " Help!" "You hit?" "Are you hit?" "No." "No." " It's all right." "The car's right there." " Okay." "We're almost home." " You good?" " I'm good." "Let's go." "Get back." "Let's get out of here!" "Roamers all over the place!" "Hurry up!" " We gotta get out of here!" " What about Sean?" " They shot him." " We gotta go." "Roamers are everywhere." " We're leaving?" " Jump!" "Hurry up, jump already." "Dude didn't make it." " Help me!" "Help me!" " I've gotta go." "I'm sorry!" "No, no, don't leave!" "Help me!" "No!" "No!" " Get Hershel." " Help!" "Help!" "Help!" "Help me!" "Hershel!" "No!" "Help!" "Hershel." "Hershel." "The gunfire must've attracted the walkers." "Where's Rick?" "He ran across." "Well, hell, we can't go without him." "Rick!" " We have to go now." " No!" " I'm sorry, son." "We have to go." " No, no, don't leave me, please." " We have to go." " We can't." " He was just shooting at us!" " He's a kid." " Please help me." " This place is crawling with walkers!" "We can't leave him!" "The fence went clean through." "There's no way we can get the leg off in one piece." " Shut up or I will shoot you!" " That may be the answer." "We're not gonna get that leg off without tearing the muscle to shreds." "He certainly can't run." "He may bleed out." "Shut up." "I'm sorry." "Shut up." "Shut up." "Maybe we should put him down." "I don't wanna see any more killing, but this is cruel." "Can't we just take the leg off?" "That hatchet still in the car?" "No, no." "Don't cut my leg off, please." " Please, not my leg." " Will this cut through the bone?" "I'll have to sever the ligaments below the kneecap, out above the tibia." "He's going to lose his lower leg." " No, don't." "No." " When we get clear of here, we're gonna have to find some tinder, cauterize the wound so he doesn't bleed out." " All right, no choice." "Hurry up." " Oh, God." "Oh, God." "Hand me that stick." "Here." "Guys, walkers." " Shut up!" " Oh, my God." "Hurry up!" "Shut up." "Oh, God!" "They're everywhere." " Hershel, how we doing over there?" " I need more hands!" "Easy, easy." "No, don't cut my leg off, please." "Come on, we gotta go!" "I'm almost out of ammo!" "We don't have much time!" "Come on, we've gotta go!" "Can't hold them off!" "Hershel, do it now!" " Come on, Hershel!" " There is no time!" "Hershel, come on!" "Please don't leave me!" "Please!" "No!" "Don't leave me!" "Please!" "Please don't leave me!" " Are you all right?" " I'm fine." "You're not fine." "I saw the wreck." "Let me look at you." " What happened?" " Looked down at the map and hit a walker." "Next time stay put, you won't need a map." " Come on, I gotta get you back." " No, we gotta find Rick." "He's back." "They're all back." "They're all safe and sound." " Really?" " Yeah." "Oh, thank God." " What are you doing?" " God." " Keeping an eye on you." " Ain't you a peach?" "I'm not gonna let you pull away." "You've earned your place." "If you spent half your time minding your daughter's business instead of sticking your nose in everybody else's, she'd Still be alive!" "Go ahead." "Go ahead and what?" "I mean, just go!" "I don't want you here!" "You're a real piece of work, lady." "What, are you gonna make this about my daddy or some crap like that?" "Man, you know jack." "You're afraid." "You're afraid 'cause you're all alone." "You got no husband, no daughter." "You don't know what to do with yourself." "You ain't my problem!" "Sophia wasn't mine!" "All you had to do was keep an eye on her!" "Hmm." "Yeah." "Oh, my God, are you all right?" "What happened?" " I was in an accident." "I'm fine, I'm fine." " She was attacked." "I really am." "Where's Rick?" "They're not back?" "Where are they?" "Look, I had to get you back here." " You asshole." " Lon." " He's my husband." " Lori, I will go after him." "I will find him." "Hey!" "Now, look, first things first." "I gotta..." "I gotta look after you." "I gotta make sure the baby's all right, okay?" "You're having a baby?" "Why didn't you tell me?" "Come on." "Let's make sure you're all right." "Come on." "Thank you." "Hey." "I am so sorry that I left without telling you." "It's okay." "I wasn't scared." "When's Dad getting back?" "Let's hope soon." "I wanna be there when you tell him about the baby." "He already knows." "We were just trying to find the right time to tell you." "Is it a boy or a girl?" "Well, we won't know that until it's born." " Will I be able to feel it?" " Not for a while." "You must have a lot of questions, huh?" "We never had the talk." "I guess we forgot." "Don't look at me." "That's your father's job." "If the baby's a girl, can we name her Sophia?" "Hey, dude." "Hey, I'm sorry, bud." "Okay?" "I thought you knew." "Big brother Carl." "Pretty cool, huh?" "I say that's very cool." "You mind if I talk to your mom a sec?" "How about a little later after she's had some rest?" "Lori, I had to get you back here." "You wouldn't have come otherwise." "How about you..." "How about you just hear me out, please?" "It's okay." "Can you give me a minute?" "Thanks, bud." "Okay." "Lori, it was a lie." "It was one little white lie." "But I think that..." "I think you ought to be thinking about how lucky we are that your baby's safe." "You just can't stop lying, can you?" "My husband is back safe and sound." "My husband is dead in some hospital." "When are you gonna..." "When are you gonna stop throwing that in my face, huh?" "I thought that he was..." "The point here, Lor, is that you cannot keep running off like that." "What are you thinking about?" "I was thinking we needed Rick here to keep us safe." "Rick?" "I keep you safe." "Like you did with Otis?" "What happened that night?" "You haven't been the same since." "You wanna know what happened with Otis?" "What happened with Otis happened because I love you." "I love you and I love Carl." "I told Rick." "What?" "You told him what?" "Did you tell him that you thought you were a widow?" "That you were grieving and that the world was coming to an end?" "That you needed comforting?" "Did you tell him it was a mistake?" "Mmm-hmm." "You know, Lori, that ain't true." "What we had, it was real." " It was not." " It was a long time coming." " It was real, Lori." " It was not." "It was you and it was me and Carl, and it was real." "It was right." "Don't say it wasn't." "It wasn't." "Just think about what you felt, just for a second." "What you felt." "Everything falling apart all around us, but it..." "It was the one good thing." "And you know it's true." "How is she?" "Dehydrated." "I'll set up an IV." "Best I can do without Hershel." "Hey." "Can I get you anything?" "I just wish my dad was here." "She'll be okay." "You just need to be strong for her." "I was just reminding her about..." "Never mind." "No, no." "I'd love to hear." "My dad would die if he heard this." "My first summer back from college," "I drove home, dumped my stuff off, went straight out to the stable for a ride." "My family comes back from church and Beth grabs my things and starts unpacking my stuff upstairs." "That's sweet." "Yeah, until this one here starts rifling through my backpack." "She finds this little plastic container with these pink and green candies inside." "She didn't even know I was on the pill." "She was so freaked out by the idea of me and boys and sex, that she runs outside and chucks them in the duck pond." "And I ride up, I see this, I'm screaming." "She's crying and Shawn runs outside, thinks one of us is drowning." "Soon as he figures out what's going on, the jerk busts out laughing so loud that my horse rears up and gets mud all over the three of us." "My dad comes out, "What the heck is going on out here?"" "And she turns around, bats her eyelids and says," ""We're just swimming, Daddy."" "In her Sunday dress, all covered in snot and mud." "Rick and Glenn will get your dad back." "Glenn's a good guy." "Yeah." "He is." "Are you sure you wanna risk it?" "You might not make it back." "I'll be fine." "And with Shane at the helm, I wouldn't be too sure." "He's lost people before." "And he's had my back." "What are you insinuating?" "He doesn't want Rick back, or Hershel." "With them gone, he's got everything he wants and no one to tell him otherwise." "Shane has done more to keep this group alive than anybody," " including Rick." " You can't possibly believe that." "I do." "Guys." "Dad!" "You're okay." "Patricia, prepare the shed for surgery." " Are you hurt?" " No, but what happened to you?" " I was in a car accident." " Accident?" "How?" " I went looking for you." " Snuck out on her own." " I brought her back." " Are you crazy?" "You could've..." "Who the hell is that?" "That's Randall." "We couldn't just leave him behind." "He would've bled out, if he lived that long." "It's gotten bad in town." "What do we do with him?" "I repaired his calf muscle as best I can, but he'll probably have nerve damage." "Won't be on his feet for at least a week." "When he is, we give him a canteen, take him out to the main road, send him on his way." "Isn't that the same as leaving him for the walkers?" " He'll have a fighting chance." " Just gonna let him go?" "He knows where we are." "He was blindfolded the whole way here." "He's not a threat." "Not a threat." "How many of them were there?" "You killed three of their men, you took one of them hostage," " but they just ain't gonna come looking?" " They left him for dead." "No one is looking." "We should still post a guard." "He's out cold right now, will be for hours." "You know what?" "I'm gonna go get him some flowers and candy." "Look at this, folks!" "We back in fantasy land!" "We haven't even dealt with what you did at my barn yet." "Let me make this perfectly clear once and for all." "This is my farm." "I wanted you gone." "Rick talked me out of it, but that doesn't mean I have to like it." "So do us both a favor." "Keep your mouth shut." "Look, we're not gonna do anything about it today." "Let's just cool off." "Can I talk to you?" "What's going on with you?" "Your dad saved my life today, and Rick saved us both." "And I..." " I froze." " Well, you were being shot at." "I know, but..." "You don't have anything to prove." "All I've done, and this, okay?" "It's because of what you said." "That I love you?" "Yeah." "A bullet hit the wall behind me and I thought of you, losing me, hurting." "And I couldn't take it, so I hid to stay alive." "Glenn." "No, no, no, you don't get it." "Rick, your dad, they were counting on me, and I only thought of myself." "Has she eaten?" "I'll give her a sedative, stop her body from working too hard." "You were drinking." "That was the least of my worries." "You left and I didn't know what to do!" " Want me to take watch?" " Yeah." "Relieve T in a few hours." "I'm gonna take the graveyard." "And then what?" "We just send him on his merry way?" "According to Rick and Hershel." "If he finds his people and leads them here, we'll have a war on our hands." "You know you're preaching to the choir, girl." "You ever consider a lighter touch?" "Abandoning the search for Sophia, taking out the walkers in the barn, lying to Lori today." "Those were all the right calls." "It's your presentation that leaves something to be desired." "Dale send you?" "I see you pushing everyone away." "For what?" "They need you." "I'll always be the odd man out." "The same as you." " I've made my peace." " Have you?" "The way I see it, you and me, we're treated the same way." "Everyone's always trying to take the gun out of your hand." "These folks, they want to play house." "They wanna pretend that Rick and Hershel, they know what they're doing." "Let me tell you something, they bound to get us all killed." " Then we have to stop that." " They don't listen." "They're gonna give this kid a care package." "They're gonna send him on his way." "And you're right, that's gonna bring on a war or something worse, and We're just gonna..." "We're gonna sit here and wait for it." "But you and me, we're the only ones who see it coming." "I should've left with you when I had the chance." "Oh, man." "Thank you." " Little help." " Come here." "Ow!" "Ow!" "We're like a couple of old people." "We need to talk about Shane." "What's he done now?" "He thinks the baby's his." "No matter what, it's yours." "He'll accept that." "You're gonna have to make him." "He won't listen to me." "He's delusional and he's dangerous." "When I went looking for you, he came after me." "Well, of course he did." "And lied to me to get me back here, said you were already back." "Wha..." "You saw what he did at the barn." "He's threatened Dale and Hershel." "He's scaring people and he's scaring me." "And I think he killed Otis." "I think he left him behind and I think..." "I think he did it not just to save Carl, but because he loves me." "But you don't know that." "And he thinks that we're supposed to be together no matter what." "Those gunmen left that kid behind today." "I killed two people myself because of you, and Carl and the baby." "It was gonna be me and not them no matter what." "You killed the living to protect what's yours?" " That's right." " Shane thinks I'm his." "He thinks the baby's his." "And he says you can't protect us, that you're gonna get us killed." "He's dangerous, Rick, and he won't stop."

Vitrification of in vitro produced bovine blastocysts: methodological studies and developmental capacity. Methodological studies were undertaken to test the validity of a three-step vitrification procedure for bovine in vitro produced embryos using glycerol and ethylene glycol as cryoprotectants. Embryos were produced in a low-phosphate culture system (medium VT1 + 10% foetal calf serum) and vitrified at day 7 post-insemination either in a mixture of 25% glycerol--25% ethylene glycol or a mixture of 10% glycerol--40% ethylene glycol. In the first mixture 67% (n = 283) of blastocysts were re-expanded after 72 h of culture and 53% were hatched while in the second one (n = 65) only 5% survived. The mean number of cells of the surviving blastocysts was correlated with the rate of survival (R2 = 0.47; P = 0.0024). Embryo size (diameter < or > to 180 microm) did not influence blastocyst survival or cell number, but hatching rate was higher for embryos > 180 microm. Embryo survival, hatching rate and cell number 72 h post-warming were not affected by the mode of vitrification (direct plunging into nitrogen liquid or vitrification into nitrogen liquid vapour), the mode of preparation of the vitrification solutions (molar or molal basis) or by the concentration of galactose used as a diluent (0 to 0.85 M). Only one calf was born after transfer of 22 vitrified blastocysts. These results confirm the apparent lack of correlation for cryopreserved embryos between in vitro survival or hatching and viability after transfer.

[Surgical treatment of pain syndrome in lumbar spine in patients with obesity]. To analyze the reduction of pain severity, time of surgery, intraoperative blood loss, incidence of unintentional lesion of dura mater, infectious complications and hospital-stay after lumbar microdiscectomy. The study included 104 patients aged 24-58 years (37 men and 67 women, mean age 45 years) who underwent lumbar microdiscectomy within January 2015 - June 2016. The main and control groups consisted of 48 and 56 patients with and without obesity respectively. In all cases lumbar microdiscectomy was made. Pain syndrome was assessed by visual analogue scale and Oswestry questionnaire. In 6 weeks, 6 and 12 months after surgery significant improvement of both lumbar and leg pain was observed. Significantly reduced pain was stable and similar in both groups within follow-up although there was a tendency to increased pain in long-term period in group 1. Blood loss and infections were slightly higher in obese group while surgery time and hospital-stay were significantly higher in these patients. Features of patients with excessive body weight should be considered prior to elective surgery. Probably, implants are advisable to stabilize spinal motion segment and improve the outcomes among patients with excessive body weight.

The long-term goal is to gain a better understanding of the biological roles of gamma (immune) interferon (IFN-gamma) and of a functionally related class of cytotoxic proteins, termed "cytotoxins". Cytotoxins include lymphotoxin (LT), monocyte/macrophage-derived cytotoxin(s) (MCT) and tumor necrosis factor. Our broad working hypothesis is that IFN-gamma and cytotoxins mutually amplify their actions and that this synergism is important in inhibiting tumor cell growth and in limiting the spread of viruses and other intracellular infectious agents. The first specific aim is to gain a better understanding of the nature, multitude and mutual relationships of the various cytotoxin proteins produced by human lymphocytes and monocytes/macrophages. To answer these questions we shall perfect the methods of production of lymphocyte-derived LT and monocyte/macrophage-derived MCT from human cells, complete the purification of these proteins and produce specific polyclonal and monoclonal antibodies against them. The second specific aim is to elucidate the mechanism by which IFN-gamma produces enhanced monocyte cytotoxicity for tumor cells and to determine the possible role of cytotoxins in this process. This part of the project is based mainly on the recently established fact that IFN-gamma is uniquely active as a modulator of monocyte/macrophage functions, including activation of monocytes for tumor cell cytotoxicity. The third specific aim is to advance our understanding of the mechanisms of action of LT and MCT and of their synergism with IFN-gamma. The study of these questions will rely mainly on the analysis of the role of cellular receptors for cytotoxins and IFN-gamma and of the fate of cytotoxins and IFN-gamma after their binding to target cells. The proposed studies are likely to provide biologically relevant and medically significant information on host defenses in malignancies and virus infections.

In a magnetic recording and reproducing device such as a tape recorder or a video tape recorder, a magnetic tape is run to be in sliding contact with a magnetic head so as to convert an electric signal to a magnetic signal or a magnetic signal to an electric signal. However, if a magnetic recording and reproducing device such as mentioned above is continued to be utilized, foreign substances adhere to a sliding surface of the magnetic head, and decrease of reproduced signals occurs by the adhesion layer. The adhering foreign substances are a whited substance generated in accordance with sliding between the magnetic head and the magnetic tape, and are regarded as being mainly composed of oxides produced by adhesion and oxidation of silicone, which is present in a slight amount in air, by frictional heat at the time of sliding or by minute energy of static electricity. Conventionally, such adhesion of foreign substances was not so large a problem; however, in recent years, according as the signal of the magnetic recording and reproducing device changes from analog to digital, or according as the recording density of the magnetic tape increases, the design precision of the magnetic head or the like is becoming severer, so that even if a minute foreign substance adheres to the magnetic head, it will have a large influence on the reading precision of the magnetic data. Particularly, if a metal vapor deposition tape capable of high-density recording is used as the magnetic tape, the adhesion of foreign substances to the magnetic head will be much, and often has an influence on the data reading precision. This seems to be due to the fact that, since the magnetic head and the metal vapor deposition tape are both made of metal materials, the heat generated by friction is large, and the amount of generated oxide is large. For this reason, prevention or reduction of adhesion of foreign substances to the magnetic head is an objective to be achieved. Restraint of the adhesion of oxides is disclosed also in Publication of Unexamined Japanese Patent Application No. 5-86005; however, the oxides herein referred to are a blacked substance produced by oxidation of an organic substance being present in air and having an unsaturated bond by an extremely large energy such as a spark at an electric contact point between a brush and a commutator, and degrade the electrical conduction state of the electric contact point. As compared with this blacked substance, the aforesaid whited substance is extremely smaller, and does not have a large influence on the electrical conductivity even if it is generated at the electric contact point, so that the problem caused by the whited substance is different from that caused by the blacked substance. The object of the present invention is to provide a magnetic recording and reproducing device that can restrain the adhesion of foreign substances to the magnetic head.

1. Field of the Invention The present invention relates to a power supply interrupting apparatus which interrupts a dark current of a battery installed on a vehicle such as an automobile, and more particularly, to a power supply interrupting apparatus which is made to interrupt a power supply in a simple operation. 2. Description of the Related Art Various types of electronic components have been installed on motor vehicles produced in recent years. An onboard battery supplies a minute current (that is, dark current) to some of the electronic components even when the vehicle is parked with an engine turned off. Due to the battery supplying current to the electronic components when the engine is off, the voltage of the onboard battery is reduced when the engine is turned off for a long period of time, resulting in a state where the onboard battery is left uncharged, leading to a flat battery (that is, the overdischarge of the onboard battery). To prevent such an incident, conventional practice is to disconnect a battery terminal from a battery, as shown in FIG. 25, when the vehicle is kept at rest for a long period of time, is put in a garage for repair, or to remove a fuse disposed upstream of a dark current consuming electronic control unit (hereinafter, referred to as “ECU”), as shown in FIG. 26, when the vehicle is transported on a transport vehicle. There is known a vehicle power supply interrupting apparatus which requires manual operation to interrupt the electric continuity (refer to JP-A-8-279321). When the power supply interrupting apparatus is pushed down, the operating portion is designed to rotate 90 degrees by a coil spring incorporated within the apparatus, and a contact, engaged with the operating portion, moves to an OFF position in association with the rotation of the operating portion, while an indication mark on the operating portion indicates an “OFF” position. Due to this, the operator can visually recognize from the position of the indication mark that a power supply line has been opened. In addition, when attempting to return the operating portion from the OFF position to an ON position, the operating portion is pushed down and rotated 90 degrees in a reverse direction to reach the ON position, and thereafter, the pressure applied to the operating portion is released. However, the method of interrupting the power supply by disconnecting the battery terminal is dangerous and troublesome to users in general. In addition, the removal of the fuse is also troublesome work. Additionally, the power supply interrupting apparatus described in Patent Document No. 1 has the problem with operability.

In this age of increased air pollution, the removal of chemicals from the air we breathe is a concern of everyone. Gas phase filtration is commonly accomplished using activated carbon manufactured in various ways. One approach comprises using a carbon/adhesive slurry to glue the carbon to the substrate. The adhesive decreases carbon performance by forming a film on its surface. A second approach involves carbonizing an organic based web by heating, followed by carbon activation. This material is high cost and has relatively low adsorption capacity. A third approach involves forming a slurry of carbon powders and fibers into sheets by a process analogous to a wet papermaking process. This material is medium-to-high cost, and has an undesirable high pressure drop. Moreover, chemically impregnated carbon particles cannot be efficiently used in conjunction with an aqueous process, as the aqueous nature of the process either washes away the chemical used to impregnate the carbon, or reacts undesirably with the impregnating chemical rendering it useless. In general, however, filter materials which do not incorporate chemically impregnated adsorbents perform far less effectively than those which do include chemically impregnated adsorbents. None of these approaches fully achieve the desired properties which provide a cost effective, high efficiency, low pressure drop, adsorptive composite.

Novel roles of complement in renal diseases and their therapeutic consequences. The complement system functions as a part of the innate immune system. Inappropriate activation of the complement pathways has a deleterious effect on kidneys. Recent advances in complement research have provided new insights into the pathogenesis of glomerular and tubulointerstitial injury associated with complement activation. A new disease entity termed 'C3 glomerulopathy' has recently been proposed and is characterized by isolated C3 deposition in glomeruli without positive staining for immunoglobulins. Genetic and functional studies have demonstrated that several different mutations and disease variants, as well as the generation of autoantibodies, are potentially associated with its pathogenesis. The data from comprehensive analyses suggest that complement dysregulation can also be associated with hemolytic uremic syndrome and more common glomerular diseases, such as IgA nephropathy and diabetic kidney disease. In addition, animal studies utilizing genetically modified mice have begun to elucidate the molecular pathomechanisms associated with the complement system. From a diagnostic point of view, a noninvasive, MRI-based method for detecting C3 has recently been developed to serve as a novel tool for diagnosing complement-mediated kidney diseases. While novel therapeutic tools related to complement regulation are emerging, studies evaluating the precise roles of the complement system in kidney diseases will still be useful for developing new therapeutic approaches.

1. Field of the Invention The present invention relates to an ornamental hair enriching equipment hardly restricted in attachment position to a head and easy to arrange complex hair of original and artificial hairs. 2. Description of the Related Art Hitherto, there are hair enriching equipments in which artificial hair (that artificial or natural hairs have been processed) is attached to a human head, and united together with his or her thin original hair (natural hair growing on his or her head) to make it look like his or her original hair having increased. Besides, there are ribbons, barrettes, beads, etc., for adorning human heads gaily. In recent years, there are ornamental equipments such as partial wigs and false hairs for producing head adornment by dyeing his or her original hair into a color impossible naturally, or mixing artificial hair of such a color with his or her original hair. FIG. 6 is a rear view of a hair enriching equipment (wig for hair enrichment) used for hair enrichment as a principal object. The hair enrichment wig 1 shown in the drawing is made in a manner that artificial hairs 3 are implanted to a flexible ventilation (implantation) member 2 with meshes of very large size, e.g., 3 cm square. The ventilation member 2 is fixed to the original hair of a wearer by a suitable method, the artificial hairs 3 are raked away from the above, and original hairs pressed down due to the wear of this hair enrichment wig 1 and lying down under it, are raked out through the meshes with a comb or a brush, and united together with the neighboring artificial hairs 3 to arrange hair. While the mesh of the ventilation member of a wig is generally very minute, e.g., 1 mm square, the mesh as described above is large because the equipment is made for a person who has relatively rich original hair and is not discomforted even by a small quantity of implanted artificial hairs 3, and because it is formed such that a large quantity of original hairs can easily be raked out. But, when a person wears it actually and tries to rake out his or her original hairs, teeth of a comb or tips of a brush may be caught by meshes though the meshes are made into a fairly large size, so he or she can not rake out his or her original hairs as he or she wishes. Even when he or she catches his or her original hairs by teeth of the comb or tips of the brush with much effort and is going to rake out them, there may then arise a trouble that the original hairs are caught by meshes and they are only swell in a loop shape and do not easily come out. Consequently, when such a hair enriching equipment is worn, the wearer must ask an experienced technical expert to rake out his or her original hairs. This was troublesome and dissatisfactory to the wearer of the hair enriching equipment. FIG. 7 is a rear view of a wig for thin-haired head (wig for hair enrichment) proposed to solve the above problem. The hair enrichment wig 5 shown in the drawing is made by the manner that a plurality of parallel linear members 7 made of a shape memory alloy is attached to an annular base 6, and artificial hairs 8 are implanted on the linear members 7. In this construction, when a person wears the hair enrichment wig 5 on his or her head and rakes out his or her original hairs, the original hairs are easily to come out merely by moving teeth of a comb or tips of a brush along the linear members 7. However, when the above hair enrichment wig 5 is actually made and worn by way of experiment, though original hairs are easy to be raked out in the central portion of the annular base 6, linear members 7 are short near both sides of the annular base 6, as a result, there arose the same trouble as that in the hair enrichment wig 1 shown in FIG. 6. Besides, because the base is limited to such an annular shape, that is, because the curved portion (R: curved shape) of the base that is the engagement portion with a head in wear, is defined, the use portion to the head is restricted and it is hard to use it on different sizes or shapes of the heads. Besides, for using a shape memory alloy for the linear members, an individual wig must be made so as to correspond to the shape of the head of the user of the wig. Consequently, a stock of the wig can not be made as products for wide use. That is, troublesome expensive products at special orders can be supplied only. It is an object of the present invention to provide a widely usable ornamental hair enriching equipment easy to rake out original hairs and capable of use for a multiple of heads. Hereinafter, constructions of ornamental hair enriching equipments according to the present invention will be described. An ornamental hair enriching equipment according to the present invention for use for personal adornment in the manner that artificial hairs of a different color is mixed with original hairs, or for use for hair enrichment in the manner that artificial hairs of the same color as that of original hair is mixed with the original hair having thinned, comprises a plurality of fastenings, a support member provided with said fastenings, a plurality of parallel elastic linear members supported by said support member at one end of each of them and disposed on said support member at predetermined intervals, and artificial hairs implanted on at least the above elastic linear members. Besides, an ornamental hair enriching equipment according to the present invention for use for personal adornment in the manner that artificial hairs of a different color is mixed with original hairs, or for use for hair enrichment in the manner that artificial hairs of the same color as that of original hair is mixed with the original hair having thinned, comprises a plurality of fastenings, a plurality of support members provided with said fastenings, a plurality of parallel elastic linear members supported by said plurality of support members at both ends of them and disposed on said plurality of support members at predetermined intervals, and artificial hairs implanted on at least the above elastic linear members. The above plurality of elastic linear members may be supported by one support member at its one end, and divisionally supported by a plurality of support members at its other end. The above plurality of elastic linear members may be disposed such that the end of the end portion supported by the above support member protrudes outward beyond the above support member, and may have a curved shape corresponding to the curved surface of a human head, and a laterally winding shape along the curved surface of the human head.

Isotropic exchange interaction between Mo and the proximal FeS center in the xanthine oxidase family member aldehyde oxidoreductase from Desulfovibrio gigas on native and polyalcohol inhibited samples: an EPR and QM/MM study. Aldehyde oxidoreductase from Desulfovibrio gigas (DgAOR) is a homodimeric molybdenum-containing protein that catalyzes the hydroxylation of aldehydes to carboxylic acids and contains a Mo-pyranopterin active site and two FeS centers called FeS 1 and FeS 2. The electron transfer reaction inside DgAOR is proposed to be performed through a chemical pathway linking Mo and the two FeS clusters involving the pyranopterin ligand. EPR studies performed on reduced as-prepared DgAOR showed that this pathway is able to transmit very weak exchange interactions between Mo(V) and reduced FeS 1. Similar EPR studies but performed on DgAOR samples inhibited with glycerol and ethylene glycol showed that the value of the exchange coupling constant J increases ~2 times upon alcohol inhibition. Structural studies in these DgAOR samples have demonstrated that the Mo-FeS 1 bridging pathway does not show significant differences, confirming that the changes in J observed upon inhibition cannot be ascribed to structural changes associated neither with pyranopterin and FeS 1 nor with changes in the electronic structure of FeS 1, as its EPR properties remain unchanged. Theoretical calculations indicate that the changes in J detected by EPR are related to changes in the electronic structure of Mo(V) determined by the replacement of the OHx labile ligand for an alcohol molecule. Since the relationship between electron transfer rate and isotropic exchange interaction, the present results suggest that the intraenzyme electron transfer process mediated by the pyranopterin moiety is governed by a Mo ligand-based regulatory mechanism.

A battery or battery system containing one or more failing battery cells and/or containers may not be capable of providing power at rated operating voltages, currents, and/or time durations. For example, lead acid batteries lose their ability to accept a charge when discharged over a period of time. Even if maintained on a battery charger, lead acid batteries will eventually fail over time due to sulfation. Ohmic value also known as internal cell resistance or impedance and cell conductance. When a battery cell starts to fail the internal resistance of the battery cell increases. Ohmic value is known to be temperature dependent. One usage for lead acid batteries is within high capacity uninterrupted power supply (UPS) systems. Typically, the high capacity UPS system is provided in the form of a number of lead acid battery cells electrically connected in series. Historically, these lead acid batteries have been characterized for an operating temperature like 77° Fahrenheit (25° Celsius) and are often used in a climate-controlled environment. A battery monitoring system may be used with the high capacity UPS system to routinely check and determine a state-of-health for each cell by measuring the cell ohmic value at 77 F. As such, dying cells can be detected and replaced prior to a failure. However, there are applications which use the battery and charger systems in extended temperature environments without climate control. As such, new methods, systems, and devices are needed to better determine the state-of-health of battery systems (e.g. high capacity UPS systems) over extended temperature ranges. Additionally, other outdoor batteries may benefit such as vehicle batteries.

Much of the sweet corn that is grown for human consumption is removed from the cob for canning and freezing while the corn kernels are still "green". Corn is considered green when the kernels are still moist and soft and have not matured into seed. One type of machine that is used in the food processing industry for this purpose is shown and described in Kerr, U.S. Pat. No. 2,787,273. This machine uses six cutting instruments with curved cutting edges that are generally positioned around a circle and around an adjustable aperture. The cutting instruments project forward from the aperture, and together with the aperture form what is known in the industry as an "iris". Ears of corn are shucked and then are fed endwise through the iris--small end first. The corn cutting instruments or "knives" are unitary or integral parts that are installed in the cutting machine. Each knife has a planar arm that reaches inward towards the center of a cylindrical cutting head where the iris is located. The arm is located in a plane transverse to the longitudinal axis of each ear fed through the aperture of the iris. At the inner or working end of the arm, the knife turns parallel to the ear, and presents a blade of some width that is formed concave relative to the ear. It is known that the blade is angled upward, from heel to toe, at a certain "cob angle" from the longitudinal axis of the ear. This allows the blade to ride up the taper of the cob from the small end to the large end as the kernels are cut off. At its free end or toe, which meets the oncoming ear of corn, the blade is sharpened to form a curved cutting edge. The curved cutting edge is more complex than a simple arcuate portion of a circle. The bottom of the blade is made concave in an arc related to a spiral cutting path around the cob. The bottom of the blade also controls the depth of the cut so that the kernels are severed at a selected height relative to the pithy part of the cob. It is also known that the cutting edge should attain a specified oblique angle, which is seen in a plane that is tangent to a midpoint of curvature for the cutting edge. It is also known that the knives of the prior art presented an edge forming a specified "edge angle" between the top surface of the blade and the bottom surface of the blade which rode along the ear. In operation of the machine, the six blades are carried by a rotating cutting head and are spun around the ear as it passes through the iris. If one of the knives cuts too deeply, a spiral gouge will be seen on the stripped cob. This is one of the observations of the cob that is indicative of corn cutting inefficiency. The geometry of the cutting edges relative to the corn kernels and the corn cob must be maintained to assure a satisfactory yield of corn kernels. After a period of use, the cutting edges become dull to the point that the yield of properly cut kernels drops. The current maintenance procedure is to remove the knives--only a small part of which is occupied by the cutting edges--and resharpen the cutting edges. This resharpening requires special equipment provided by the machine manufacturer and considerable labor for the many instances when resharpening is necessary. The machine manufacturer also recommends that periodically the knives be returned to a manufactureroperated, central sharpening facility, where the knives can be rehoned, reground and generally returned to an acceptable cutting profile. Even with these procedures, there is a further disadvantage that the blade becomes shorter with repeated resharpening and rehoning, and the original cuttin knife condition cannot be fully restored.

The cyber-attack on an information system is rapidly increasing, and a countermeasure against the cyber-attack is required. As an intrusion route of the cyber-attack, a network and a USB memory are well known. Conventionally, as a technique for preventing the cyber-attack from the network, there is a packet filter. The packet filter has a mechanism to permit or deny a packet to pass in accordance with the rule set. The rule set consists of a condition to be satisfied by the packet and a rule describing an action of when the packet satisfies the condition. The action herein is to permit or deny the packet to pass. There is order in a sequence of rules within the rule set, and the packet is collated with the rule in accordance with the order. “The packet matches the rule” or “the packet and the rule much” means that the packet satisfies the condition described in the rule. When receiving the packet, the packet filter collates the packet with the rule in accordance with the order within the rule set. If the packet matches the rule, the packet is permitted or denied in accordance with the action defined in the rule. If the packet does not match the rule, it is continued to collate the packet with a next rule. At the end of the rule set, a rule called a default rule which matches all packets is set. Accordingly, even if the packet does not match any other rule, the packet is always processed by the default rule. As the system and the attack on the system become more complicated, a corresponding rule set for packet filtering becomes larger. On the other hand, since the packet is collated with the rule one by one in accordance with the order, as the number of rules increases, in proportion to that, it takes longer to complete collation. Therefore, a technique for improving processing efficiency is necessary. Patent Literature 1 discloses a technique for speeding up a packet filter by swapping order of rules within a rule set. An idea of Patent Literature 1 is to improve processing efficiency by moving a rule which matches a packet more frequently earlier in the order, and a rule which matches a packet less frequently later in the order. For that purpose, the rules are dynamically swapped in the rule set. That is, at a time of operating the packet filter, the number of times each rule matches a packet is recorded, and in accordance with that number of times, the rules are swapped. However, it is not allowed to result in changing meaning of the rule set by swapping the rules. Thus, only when two rules do not conflict with each other, these two rules are swapped. Here, the two rules are said to conflict with each other if actions of these rules are different, and if there is an overlap in any of conditions described in these rules. For example, a condition specified in a destination address is considered. If a range from 192.168.0.1 to 192.168.0.100 is described in a rule as a condition, and a range from 192.168.0.50 to 192.168.0.150 is described in other rule as a condition, these conditions are overlapped with each other. Non-Patent Literature 1 discloses a technique for speeding up a packet filter by, before performing usual collation, performing other collation processing to filter out most of packets at high speed. If it is supposed that a rule is a logical expression and a bit string of a packet is a value to be substituted into the logical expression, the packet matches the rule only when a value of the logical expression is 1 and matching is limited at that time. Therefore, collation of the packet with the rule can be realized by the calculation of the logical expression. Hence, high speed collation can be realized by a data structure suitable for the calculation of the value of the logical expression. In Non-Patent Literature 1, the high speed collation is realized by a data structure which is a tree structure called a BDD. However, since a large storage area is necessary in order to represent the rule set using the BDD, it is difficult to represent the entire rule set using the BDD. Hence, scanning a tree of the BDD is terminated to a certain depth. This is performed as preprocessing of the original packet filter, the most of packets are filtered out, and the usual collation processing is performed on remaining packets. Thus, it is possible to shorten a time to process the entire packet filter.

Prokaryotic diversity, distribution, and insights into their role in biogeochemical cycling in marine basalts. We used molecular techniques to analyze basalts of varying ages that were collected from the East Pacific Rise, 9 degrees N, from the rift axis of the Juan de Fuca Ridge and from neighboring seamounts. Cluster analysis of 16S rDNA terminal restriction fragment polymorphism data revealed that basalt endoliths are distinct from seawater and that communities clustered, to some degree, based on the age of the host rock. This age-based clustering suggests that alteration processes may affect community structure. Cloning and sequencing of bacterial and archaeal 16S rRNA genes revealed 12 different phyla and subphyla associated with basalts. These include the Gemmatimonadetes, Nitrospirae, the candidate phylum SBR1093 in the bacteria, and in the Archaea Marine Benthic Group B, none of which have been previously reported in basalts. We delineated novel ocean crust clades in the gamma-Proteobacteria, Planctomycetes and Actinobacteria that are composed entirely of basalt-associated microflora, and may represent basalt ecotypes. Finally, microarray analysis of functional genes in basalt revealed that genes coding for previously unreported processes such as carbon fixation, methane oxidation, methanogenesis and nitrogen fixation are present, suggesting that basalts harbor previously unrecognized metabolic diversity. These novel processes could exert a profound influence on ocean chemistry.

The invention is in the field of semiconductor technology and relates to a method for fabricating a microelectronic structure having the following steps: providing a semiconductor substrate having a main area and at least one trench disposed at the main area, the trench having at least one side wall and the side wall and the main area having at least one common edge region; filling the trench with an insulating material leaving the edge region uncovered; and oxidizing the main area and the edge region to form an oxide layer having a thickness in the edge region at least just as great as at the main area. During the fabrication of integrated circuits, active components disposed in the semiconductor substrate have to be suitably insulated from one another. One possibility for doing that resides in insulating the active components from one another through the use of trench isolation (so-called Shallow Trench Isolation (STI)). In that type of insulation, trenches are etched into the semiconductor substrate and subsequently filled with an insulating material. Instances of such trench isolation can be found, for example, in German Published, Non-Prosecuted Patent Application DE 197 31 203 A1 and German Patent DE 195 35 629 C1. In the methods described therein, an oxide layer serving as gate oxide and a polysilicon layer serving as gate electrode are applied to the semiconductor substrate. Afterwards, trenches are etched into that layer system down into the semiconductor substrate. The trenches define the position of the individual active components. Finally, the trenches are filled with a thermal oxide. In those methods, however, it has turned out to be problematic that in the course of filling the trenches, the semiconductor substrate and the polysilicon may be partially oxidized, thereby producing a gate dielectric having a varying thickness. In order to minimize that problem, German Patent DE 197 31 203 C1 proposes implanting nitrogen into the gate dielectric after the formation of the gate oxide and before the filling of the trenches, in order to thereby limit the lateral oxygen diffusion. It has been shown, however, that such a measure also cannot completely eliminate the problem. U.S. Pat. No. 5,882,993 discloses the use of nitrogen for forming gate dielectrics of varying thicknesses. To that end, nitrogen is implanted in a laterally varying concentration into a silicon substrate provided with trenches that have already been filled, and an oxide is subsequently formed thereon. However, due to the varying nitrogen concentration in the silicon substrate, oxides of varying thicknesses are formed which may often have an inhomogeneous thickness in the transition regions to the trenches that have already been filled. It is problematic, moreover, that gate oxides are often severely thinned at the transition regions from the silicon substrate to the isolation trenches (e.g. so-called Shallow Trench Isolation). So-called corner devices form at the transition regions. The corner devices usually have a lower threshold voltage than the actual transistor and, as a result, adversely affect the switching characteristic and the leakage current behavior of the entire transistor. That behavior is additionally aggravated by a thin gate oxide at the transition regions. The effect of the corner device has usually been reduced through the use of a higher channel doping, but that in turn entails undesirable side effects. In order to avoid the corner device, International Publication No. WO 99/25018 attempts to damage the edge region between the main area and the trench by amorphizing implantation. The aim is to produce a somewhat thicker oxide layer there in the course of the subsequent oxidation. The method mentioned in the introduction, on the other hand, is disclosed e.g. in U.S. Pat. No. 5,891,787, where, after the formation and filling of a trench, silicon is implanted into the edge regions between the trench and the main area. That implantation is intended to bring about an excess of silicon atoms in the edge region with the main area covered, so that a thicker oxide layer than in the region of the main area can be produced there in the course of the subsequent oxidation. The implantation of nitrogen for the formation of diffusion barrier centers and elimination of crystal defects is described as an alternative. Although local thickening of the oxide layer serving as gate dielectric can be achieved by that method, microelectronic structures that are fabricated in that way only exhibit unsatisfactory properties. That is due, for example, to the fact that the oxide layer produced due to the silicon excess has a different material structure than that formed on the main area and exhibits an increased leakage current tendency. The formation of the corner device is thereby likewise only suppressed to an insufficient extent. It is accordingly an object of the invention to provide a method for fabricating a microelectronic structure, which overcomes the hereinafore-mentioned disadvantages of the heretofore-known methods of this general type and which enables largely homogeneous gate dielectrics to be formed, with the formation of a corner device being suppressed. With the foregoing and other objects in view there is provided, in accordance with the invention, a method for fabricating a microelectronic structure, which comprises the following steps providing a semiconductor substrate having a main area and at least one trench disposed at the main area, the at least one trench having at least one side wall, and the at least one side wall and the main area having at least one common edge region; filling the trench with an insulating material leaving the edge region uncovered; introducing nitrogen into the semiconductor substrate to provide a higher nitrogen concentration in the vicinity of the main area than in the edge region; and then oxidizing the main area and the edge region to form an oxide layer with a thickness in the edge region at least just as great as on the main area, the nitrogen causing the oxide layer to grow more slowly in the main area than in the edge region. According to the present invention, a semiconductor substrate is provided and at least one trench having a side wall is introduced at the main area of the semiconductor substrate. This trench defines, for example, the position of an active component in the semiconductor substrate. In the transition region between the side wall of the trench and the main area of the semiconductor substrate there is an edge region formed by both of them. Nitrogen is subsequently introduced into the semiconductor substrate, with a higher nitrogen concentration being sought in the region of the main area than in the edge region. In this case, the difference in nitrogen concentration should be dimensioned in such a way that oxide layers each having a predetermined thickness are produced in the course of subsequent oxidation of the semiconductor substrate, i.e. of the main area and of the edge region. In the common edge region between the main area and the side wall, the nitrogen concentration preferably uniformly decreases in the direction of the side wall. The effect that is intended to be achieved as a result of this is that the oxide layer which is subsequently to be formed has an increasing thickness in the edge region and thereby contributes to a uniform transition from the oxide layer thickness on the main area to the oxide layer thickness on the side wall. In this case, however, what is sought is an oxide layer thickness that is as uniform as possible as far as the edge region and even into the edge region. The particular effect achieved through the use of the method according to the invention is that the oxide layer is not thinned in a disturbing manner in the edge region between the main area and the side wall, and the undesirable influence on the transistor properties by the so-called corner device is thereby avoided. The effect of the corner device is disturbing particularly in the case of a cell transistor required for DRAM cells since, due to increased leakage currents, the stored charge flows away undesirably faster and the memory cell thus has to be refreshed again in shorter time intervals. A further advantage of the use of the method according to the invention resides in the fact that the lower threshold voltage of the corner device in comparison with the cell transistor (the threshold voltage is lower even given an identical oxide thickness of the corner device and of the cell transistor), can be compensated for by a thicker gate oxide in the edge region. It has been shown that by targeted retardation of the oxidation of the main area by the nitrogen introduced beforehand, a relatively uniform oxide layer having a sufficient thickness in the edge region can be formed. Nitrogen is preferably introduced by implantation into the semiconductor substrate, in which case it has proved favorable for nitrogen to be implanted essentially only at the main area and partially in the edge region. This can be achieved, for example, by nitrogen being introduced into the semiconductor substrate by implantation which is to the greatest possible extent perpendicular to the main area. However, the implantation angle relative to the main area may also encompass a certain solid angle range in order to ensure sufficient implantation of nitrogen in the edge region as well. The implantation of nitrogen should preferably be performed very near the surface, and this can be achieved, for example, by an implantation energy of 10-30 keV. By virtue of the largely perpendicular implantation near the surface, it is possible to establish e.g. a ratio of the nitrogen concentration at the main area to that at the edge region of, preferably, greater than 2 to 1, which manifests itself in a distinctly varying oxide thickness. A further advantage of the method according to the invention resides in the fact that, due to the compensated threshold voltage of the corner device, it is possible to dispense with a higher doping of the semiconductor substrate. The relatively high doping of the semiconductor substrate is generally used to counteract the decreased threshold voltage of the corner device. However, this high doping, which may be present, for example, in the form of a well doping, unfavorably induces a further leakage mechanism. The latter is referred to as so-called xe2x80x9cjunction leakagexe2x80x9d and manifests itself in a defect-driven and field-driven leakage current in the space charge zone of the PN junction between a source or drain region and the semiconductor substrate. This type of leakage current is predominant particularly in MOSFET transistors having a small channel width. The relatively high doping of the well, i.e. of the channel region, that is usually necessary can therefore be dispensed with when the method according to the invention is used. As a result, reliable transistors can thus be fabricated which are distinguished, in particular, by a lower leakage current rate and a more accurately defined threshold voltage. Other features which are considered as characteristic for the invention are set forth in the appended claims. Although the invention is illustrated and described herein as embodied in a method for fabricating a microelectronic structure, it is nevertheless not intended to be limited to the details shown, since various modifications and structural changes may be made therein without departing from the spirit of the invention and within the scope and range of equivalents of the claims. The construction and method of operation of the invention, however, together with additional objects and advantages thereof will be best understood from the following description of specific embodiments when read in connection with the accompanying drawings.

A common form of pointing device for use with computers and the like is referred to as a “mouse”. The computer user moves the device over a surface to move a cursor on the computer screen. The amount of motion and the direction of motion of the mouse are sensed by the device and determine the distance and direction in which the cursor moves on the screen. Inexpensive mice based on a ball that rolls over the surface have been used for some time. The ball turns two cylinders that sense the distance and direction of motion. Unfortunately, the ball picks up grease and other dirt from the surface and transfers this material to the cylinders. The resulting coating on the cylinders interferes with the motion of the cylinders, and hence, the devices must be cleaned periodically. The cleaning operation is awkward and time consuming. Mice based on optical sensing avoid this problem. Originally, such mice had to be moved over a special pad that had grid lines that were sensed by the device. The need to use this special pad made these devices less attractive than the mechanical mice discussed above. Recently, optical mice that do not require such pads have been developed. These mice include a light source that illuminates the surface under the mouse at a shallow angle, which accentuates the structural details of the surface. An image sensor in the mouse records an image of the illuminated surface periodically. By comparing two successive images, the displacement of the mouse between the times at which the images were taken can be determined. Wireless optical mice are particularly attractive since the user is not constrained by a cable connecting the pointing device to the computer. Battery life is an important consideration in such systems both from the standpoint of operating cost and convenience. Hence, systems with reduced power demands are of particular value.

The present invention relates to stationary rings surrounding gas passages in a gas turbine, and more particularly it relates to cooling stationary rings in a gas turbine. A gas turbine, in particular a high pressure turbine of a turbomachine, typically comprises a plurality of stationary vanes alternating with a plurality of moving blades in the passage for hot gas coming from the combustion chamber of the turbomachine. The moving blades on the turbine are surrounded over their entire circumference by a stationary ring that is generally made up of a plurality of ring segments. These ring segments define part of the flow passage for hot gas passing through the blades of the turbine. The ring segments of the turbine are thus subjected to the high temperatures of the hot gas coming from the combustion chamber of the turbomachine. To enable the turbine ring to withstand the temperature and mechanical stresses to which it is subjected, it is necessary to provide the ring segments with cooling devices. One of the known methods of cooling consists in feeding cooling air to an impact plate mounted on the bodies of the ring segments. The plate is provided with a plurality of orifices for passing air which, under the pressure difference between the sides of the plate, comes to cool the ring segment by impact. The cooling air is then exhausted into the hot gas passage via holes formed through the ring segment. Such a method does not enable effective and uniform cooling of the ring segments to be obtained, particularly at the upstream ends of the ring segments which constitute a zone that is particularly exposed to hot gas. This therefore has an affect on the lifetime of the ring segment. Furthermore, that technology requires too great an amount of cooling air to be taken, thereby decreasing the performance of the turbine.

Patient involvement in a professional body: reflections and commentary. The purpose of this paper is to consider the issues which emerge when an autonomous, professional, member-led organisation attempts to demonstrate its accountability to patients through lay involvement in its standard-setting processes. The paper reports a project, which is still in progress and could be described as action research. Data were collected through participant observation in a series of discussions and working groups. A limited literature search was carried out at the start of the initiative but found little which relates to lay involvement in professional bodies. The paper finds that patient involvement in a professional body is unlikely by itself to be a useful mechanism for delivering greater professional accountability. The paper is a single case study and can only suggest hypotheses for further research. The paper shows that professional bodies of various types are increasingly being asked to demonstrate public involvement in their decision making. It is important to identify the most effective mechanisms for this and the limitations inherent in the structures of organisations, which are accountable primarily to their members. The paper shows that individual doctors are held to account through a number of mechanisms, but little attention has been given to how medical professional bodies can be made more accountable for the collective power they hold. Patient involvement is interpreted within a consumerist model, which focuses on the doctor-patient relationship and ignores the considerable strategic influence which medical royal colleges exercise within the health service.

Spectrum of disease and outcome of complicated diverticular disease. Diverticular disease is a common entity. The presentation, investigations performed, and management are variable. Our objectives were to assess the presentation, extent of disease, and treatment of a cohort of patients with colonic diverticulitis. All patients with a diagnosis of diverticulitis over a 9-year period were reviewed. Patients were assessed as to age, sex, presenting symptoms, diagnostic studies, extent of disease, treatment, and outcome. Over a 9-year period (1992 to 2001), 192 patients were admitted with a diagnosis of colonic diverticulitis. The mean age was 61 years (range 28 to 90); 113 of 192 (59%) were female. The mean duration of symptoms prior to presentation was 14 days (range 1 to 270 days). One hundred eighteen of 192 (61%) had a previous documented attack of diverticulitis. Of the investigations performed 128 of 192 (66.7%) had a computed tomography (CT) scan of the abdomen and pelvis, 37 of 192 (20%) underwent a contrast enema, 61 of 192 (32%) underwent colonoscopy and 2 of 192 (1%) underwent a small bowel series. The abnormal findings on the CT scan were as follows: diverticular abscess (16%), diverticulitis (37%), diverticulosis without inflammation (15%), free air (10%) and fistula (1%). The locations of the diverticular abscesses were: pelvic (36%), pericolic sigmoid (36%), and "other," which included interloop (28%). Preoperative abscess drainage occurred in 10 of 192 (5%), which were either percutaneous, 6 of 192 (3%), or transrectal, 4 of 192 (2%). Nine of 192 (6%) presented with a fistula, colovesical fistulae (3%), colocutaneous (1%), enterocolic (1%), or colovaginal (1%). Overall, 73 of 192 (38%) underwent surgery. All patients undergoing surgery had a resection of their colon. The operative findings were localized abscess in 16 of 73 (22%), purulent/feculent peritonitis in 12 of 73 (17%), and phlegmon in 10 of 73 (14%). Sixty-seven of 73 (92%) had a primary resection with anastomosis; 38 of 67 (56%) had a protecting stoma. Five of 73 (7%) patients were found to have an unsuspected carcinoma. Overall, 29 of 192 (15%) developed a complication related to diverticulitis. Morbidity was 15.1%, of which 34% was infection related. Four of 192 patients (2%) died. In our experience, most patients presented with abdominal pain predominantly in the left lower quadrant. The symptoms were present on average of 14 days, most were female (59%), and most patients had a previous attack of diverticulitis. The commonest investigation performed was a CT scan (66.7%); however, other investigations were performed, for example, barium enemas. The practice of resection and primary anastomosis for acute diverticulitis has an acceptable morbidity and mortality. For high-risk anastomoses, a covering loop ileostomy and not a Hartmann's procedure is preferred. Surgery remains safe for the majority of patients and is associated with resolution of symptoms. We believe that because of the high number of patients in our series who had a previous attack of diverticulitis, therapy should be focused on preventing recurrent and virulent attacks by earlier operative intervention.

1. Field of the Invention The present invention relates to a binding device for forming a fold line on a booklet and an image forming apparatus having this. 2. Description of the Related Art Conventionally, a binding device for folding a sheet outputted from a main body of an image forming apparatus such as a copying machine and a printer in half and sewing the inside of a book has been known. The constitution of such a binding device is disclosed in Japanese Patent Application Laid-Open No. 61-2671. In addition, FIG. 16 shows a schematic block diagram of a main body of a conventional image forming apparatus 10 and a binding device 11 on their cross sections, which are disclosed in JP-A No. 61-2671. As shown in FIG. 16, the binding device 11 is provided with a stack tray 12 as a sheet stacking portion, a folding knife 15 as a folding portion, and a folding roller pair 16 as a fold line forming portion. On the stack tray 12, an opening portion 14 is disposed on its center portion, and a stopper 13 for stopping the sheet on a fixed position is disposed on an end portion of the stack tray 12. In addition, on the upper part of the opening portion 14 of the stack tray 12, the folding knife 15 is disposed so as to be capable of rising and falling. When the sheets are conveyed from the main body of the image forming apparatus 10 to the binding device 11, the conveyed sheets material are stacked on the stack tray 12 in series. Then, the folding knife 15 that is disposed upward of the stack tray 12 falls on the sheets stacked on the stack tray 12, and the folding knife 15 strikes the center portion of the sheet so as to fold the sheet and push the sheet into the opening portion 14 of the stack tray 12. In the following explanations, a plurality of sheets stacked on the stack tray 12 being folded down calls a booklet. Sheets pushed into the opening portion 14 of the stack tray 12 is folded down to be made into a booklet. After that, the booklet is provided to the folding roller pairs 16 being folded down. The folding roller pairs 16 forms a fold line on the center portion of the booklet by conveying the booklet provided while sandwiching it from the opposite sides. The booklet having the fold line formed thereon is conveyed on a tray 17 due to rotation of the folding roller pairs 16 to be stacked on the tray 17. However, when a pressure applied by the folding roller pair 16 is released, the booklet is opened by its own elasticity and a fold line of the booklet formed by the conventional bookbinding apparatus 11 is occasionally returned to the original state. As a result, the booklet has a poor-looking appearance such that the fold line is opened. The problem relating to the opening of the fold line is most obvious in the case where sheets whose opening amount is large are used as sheets composing a booklet. The sheets whose opening amount is large mean sheets which are once folded but are easily opened including sheets such as cardboard whose rigidity is high and sheets such as thin paper whose rigidity is low but whose periphery has a small water amount in a low-humidity environment. When a fold line is formed by bending sheets whose opening amount is originally small to a direction orthogonal to a fiber orientation of the sheets, the sheets are easily opened greatly. Such sheets are, therefore, regarded as sheets whose opening amount is large. The problem relating to the opening of the sheet is not eliminated to not less than a certain degree even by increasing a pressure to be applied by the folding roller pair 16. For this reason, solving means other than the method for increasing the pressure by the folding roller pair 16 is required. As one example of the solving means, Japanese Patent Application Laid-Open No. 11-157247 discloses a method for humidifying sheets using a humidifying unit so as to ease the forming of fold lines of the sheets. FIG. 17 is a schematic block diagram on a cross section of the binding device 11 having humidifying unit disclosed in JP-A No. 11-157247. The bookbinding device 11 shown in FIG. 17 is provided with a humidifying chamber 18 as a humidifying unit, humidifying nozzles 19 and 20, and a heating roller pair 30 as a heating portion. In FIG. 17, the humidifying chamber 18 humidifies sheets which are being conveyed on an upper stream side of the stack tray 12. The humidifying nozzle 19 humidifies a part of a booklet to be folded on an upper stream side of the folding roller pair 16. The humidifying nozzle 20 humidifies a part of a booklet to be folded on a lower stream side of the folding roller pair 16. When these humidifying units 18, 19, and 20 humidify a part of a booklet to be folded, even if sheets whose opening amount is large are used, before a fold line is formed by the folding roller pair 16, the opening amount of the sheets can be reduced. Therefore, a fold line can be easily formed by the folding roller pair 16, so that a good-looking booklet without opening can be provided. In the bookbinding apparatus 11 having the humidifying units disclosed in Japanese Patent Application Laid-Open No. 11-157247, however, a humidifying condition is not changed according to sheets in which a fold line is formed. For this reason, in the case of a booklet made of particularly sheets which water hardly penetrates such as sheets whose surface is specially treated, the sheets are curled to a direction where the booklet opens, and thus the booklet might have a poor-looking appearance. In the conventional humidifying units, since the humidifying chamber 18 is constituted so as to humidify also a portion of a sheet which is not folded, this unnecessary humidifying causes inefficiency of the device. As shown in FIG. 17, since the humidifying nozzles 19 and 20 humidify only a sheet on an outmost position of a booklet in the sheets composing the booklet, it is difficult to humidify sheets on an inner position of the booklet. As a result, the opening amount of the sheets on the inner position with respect to the sheet on the outer position of the booklet cannot be sufficiently reduced, and thus the booklet might have a poor-looking appearance where the opening occurs. In addition, the portion of the sheet that is humidified by the humidifying nozzle 19 is exposed from an opening portion 14 of the stack tray 12 to the outside. Therefore, water given by the humidifying nozzle 19 evaporates around the area till the booklet is folded down on the inside by the folding roller pairs 16. As a result, since the opening amount of the sheet cannot be sufficiently reduced, the booklet might have a poor-looking appearance where opening occurs. A phenomenon from the humidifying of the sheets to the occurrence of a curl is described with reference to FIGS. 18A, 18B, and 18C. FIGS. 18A, 18B, and 18C are pattern diagrams showing a cross section of humidified sheets. In the drawings, a portion humidified by the humidifying units (hatched portion in the drawings) once stretches just after humidifying, but when the sheets are again dried, forces to a direction where the sheets further shrink with respect to the shape before humidifying are generated as shown by arrows in the drawings. On the other hand, a portion which is not humidified is hardly influenced by humidifying and drying, and thus it does not stretch nor shrink. Therefore, a shrinkage amount is different between the portion to be humidified and the portion which is not humidified. As a result, when the sheets are humidified, the sheets are easily curled to a direction where the humidified surfaces of the sheets shrink. That is, as shown in FIG. 18C, in the case where the inner side of the booklet shrinks due to the humidifying of the inner side, the sheets are curled to a direction where the booklet is closed. As a result, the sheets do not open, and the booklet does not have a poor-looking appearance. As shown in FIG. 18A, however, since the humidifying nozzles 19 and 20 humidify the outer side of the booklet, the outer side of the booklet shrinks. Therefore, the sheets are curled to the direction where the booklet is opened, the opening occurs, and the booklet might have a poor-looking appearance.

Lockable push button actuator mechanisms suitable for use with mechanical locking systems such as are used on large tool containers and the like are well known. Patents that disclose such lockable push button actuator mechanisms that are well suited for use with mechanical locking systems include U.S. Pat. No. 7,126,066 issued Oct. 24, 2006, U.S. Pat. No. 7,205,492 issued Apr. 17, 2007, and U.S. Pat. No. 8,084,701 issued Dec. 27, 2011. These patents are referred to later herein as the Lockable Push Button Actuator Patents, and their disclosures are incorporated herein by reference. Lockable push button actuator mechanisms such as are disclosed in above-identified patents each have a generally tubular housing that can be mounted in an opening formed through a metal panel of a large tool container or the like. The housing typically has a relatively large diameter front bezel that defines a front face of the housing, and smaller diameter portions that extend rearwardly from the front bezel. A push button subassembly is mounted for forward and rearward movement within a passage that extends centrally through the housing. The subassembly has a push button that is biased to project forwardly from the front face of the housing. A keyway opens forwardly through the front of the push button, and is designed to receive a key that can be turned between locked and unlocked orientations when a suitably configured key is inserted into the keyway. The locked and unlocked orientations to which the keyway can be turned are prominently marked by symbols provided on the front face of the housing. The push button can be manually depressed to a protected position where the push button can be latchingly retained substantially flush with the front face of the housing when the keyway is turned to the locked orientation. Among other components of the lockable push button actuator mechanism are a tubular rear component that projects rearwardly from the housing, and a plunger that is carried inside the tubular rear component. If the keyway is turned to the unlocked orientation, both the tubular rear component and the plunger are drivingly connected to the push button, and therefore move forwardly and rearwardly in unison with the push button. If the keyway is turned to the locked orientation, only the plunger is drivingly connected to the push button, hence only the plunger moves rearwardly when the push button is depressed. When the rearwardly moving push button reaches a protected depressed position with the keyway turned to the locked orientation, it is latchingly retained substantially flush with the front face of the housing. Connected to the rear end region of the tubular rear component is a tapered, nosecone shaped member which defines at its rearmost end an engagement surface that is commonly used to operate components of a mechanical locking system. When the keyway at the front of the push button is turned to the unlocked orientation, the tubular rear component and the nosecone shaped member connected thereto are both drivingly connected to the push button and therefore move forwardly and rearwardly in unison with the push button—hence the engagement surface moves forwardly and rearwardly with the push button. However, when the keyway is turned to the locked orientation, the tubular rear component and the engagement surface connected thereto do not move rearwardly when the push button is depressed, but the plunger situated inside the tubular rear component does move rearwardly with the depression of the push button, which is a feature of relative movement (of the tubular rear component and the plunger situated inside the tubular rear component) that has not been used until now to operate anything. As will be explained, the present invention makes use of a relative movement that can take place between the tubular rear component and the plunger situated inside the tubular rear component to operate an electrical switch when the push button is depressed under certain conditions, namely when the keyway of the push button is turned to the vertical locked orientation. To retrofit existing lockable push button actuator assemblies or mechanisms to make use of this relative movement, the present invention calls for a nosecone shaped member that is carried by the tubular rear component to be removed and replaced by an adapter that carries an electrical switch having an operator that can be engaged by the plunger to operate the electrical switch when certain relative movement takes place between the tubular rear component and the plunger—thereby enabling a lockable push button actuator (which has been retrofitted by removing its nosecone shaped member and replacing it with an electrical switch) to be used as a component of an electrically operated locking system.

In order to protect the products from damage due to mechanical, physical and chemical influences from the outside, various coating layers or coating films are being applied to the surface of electric and electronic devices such as mobile phones or various display devices, etc., components of electronic materials, household appliances, automobile interior and exterior materials, or various molded products such as various plastic products. However, scratches on the coated surface of the products or cracks due to external shocks deteriorate the appearance characteristic, main performance and lifespan of the products, and therefore various studies are being conducted to protect the surface of the products, thereby maintaining the quality of the products for a long period of time. In particular, research and interest in coating materials having self-healing properties have been rapidly increasing in recent years. The self-healing property refers to a property in which, when scratches are made on the coating layer by an external physical force or stimulus applied to the coating layer, the damage such as scratches is gradually healed or reduced itself. Although various coating materials exhibiting such a self-healing property, or mechanisms of the self-healing property are known, in general, a method for using a coating material exhibiting elasticity is widely known. That is, when such a coating material is used, even if a physical damage such as scratches is applied on the coating layer, the damage site is gradually filled in because of the elasticity of the coating material itself, and thus, the self-healing property described above may be exhibited. However, in the case of a conventional coating layer exhibiting the self-healing property, it had disadvantages in that the mechanical properties of the coating layer such as hardness, abrasion resistance or coating strength, etc. were insufficient as elastic materials were mainly included. In particular, in the case of applying a coating layer exhibiting a self-healing property to the exterior of various household appliances such as refrigerators or washing machines, etc., the mechanical properties of the coating layer are required on a high level, but in most cases, the coating layer having a conventional self-healing property could not satisfy such high mechanical properties. Accordingly, when a strong external stimulus was applied to the existing coating layer, there were many cases where the coating layer itself was permanently damaged, and the self-healing property was also lost. Due to such problems of the prior arts, there has been a continuing demand for the development of a technique that enables the provision of a coating layer or film that exhibits further improved mechanical properties together with excellent self-healing properties.

"Left!" "3rd!" "Jean-Louis Schlesser in his mean machine, No.10. 10 like Zidane!" "30 meters, left!" "Brake!" "World rally champion in '98 and '99... winner of the Paris" " Dakar:" "The man to beat!" "Left, top speed!" "Get a move on!" "We'll get slaughtered." "I'm flat out!" "The guy behind's flatter out!" "Watch out!" "He's flashing me!" "Isn't that Vatanen?" "No, a taxi!" "Move your crate!" "I'm working here!" "Is it the right road?" " Short cut!" "Short cut." "Don't let a taxi win!" " No way." "Sorry, folks." "A tourist's blocks the road!" "It looks more like a race car." "It's just a clown in a "babe magnet"!" "A taxi on our tail sure looks bad!" "I'll shake him now." "He rammed me!" "Enough!" "We'll be here all week!" "Nearly there, lady." "Why... why are there so many people here?" "They're in vacation." "Oh, right!" "C'mon, Jean-Louis!" " Bravo, Jean-Louis!" "No.10..." "It's not Schlesser!" "A taxi." "I didn't catch his number." "17 minutes 25 secs!" "People always throw up after!" "Never during!" "OK, lady?" "Who's it for?" " Her!" "Her water broke!" "May I?" "You're giving birth!" " Well, I ain't knitting!" "Get the gear!" "We'll do it here!" "Hey, doc, I gotta run." "Use the ground, not my seat!" "Water's broken!" "Water breaks?" "Push!" "Breathe!" "Push!" "Hi, Lilly." "30 minutes late for lunch with my folks!" "Yeah, I'm on my way." "Daniel, you're finally meeting my Dad." "He's expecting you!" "This is a super-big emergency!" "What are my folks?" "Diesel?" "Lilly, come on!" "Mom's edgy, Dad's pacing the floor." "But hey, take your time!" "I can't help it, I'm stuck tight here!" ""Stuck"?" "Who's yelling?" "It's... a woman." "Thanks!" "I guessed that much!" "What's up?" "I'm just watching." "It's not what you think, you hear me?" "I can hear that bitch!" "Is it someone I know?" "No!" "I don't know her either!" "I just met her!" "Oh, I feel it now!" "I feel it!" "Don't fuck with me!" "You've got some slut there while I wait for you!" "No!" "This big woman's yelling 'cause her water snapped!" "Her husband's here." " Husband, too?" "A threesome in a car!" "Oh, no!" "Someone tell her!" "I don't know I can." "Here!" "This is your fault." "I'm the husband." "It's marvellous!" "Daniel, he's dead meat!" "He's all shook up, that's all." "Want to talk to the doctor?" "A doctor, too!" "Lilly, I swear it's the truth!" "The baby's coming out." "It's a baby, I swear!" " A baby?" "I see the head!" "I think it's a head!" "Your baby?" "No, it's not!" "He's nothing like me I swear!" "He's as wrinkly as an old garden gnome!" "Marvellous!" "You're messing me about!" " Just listen!" "This woman just gave birth." "Outside the clinic, in my taxi!" "She's ruined my back seat!" "Don't hit that poor kid!" "I can't hear a thing now!" "Marvellous!" "You be there when I give birth!" "I can sit and wait if you like." "This place looks fine." "You got 10 minutes!" "Not twins?" "Is it a wrap?" "No offence, but I gotta run!" "Ah, hon!" "Problem with your friend?" "An emergency at the hospital." "A difficult birth." "I understand." "Saving lives all day." "I respect that." "I don't know what to say." "You were wonderful!" "I know!" " I hope you won't lose your license." "I don't have one!" "I am quite pleased... moved, even... to give you... your first... driver's... license!" "You sure?" " Yep!" "I don't want to twist your arm." "No doubt about it, it's just fine!" "It's not 'cause it's my 27th time?" "Your 100th time would be the same!" "You're ready." "Really ready." "OK, I accept." " That's fine." "I'll back out." " No!" "Leave it!" "Don't touch!" "Leave it!" "I'll do it!" "I'll sort it out!" "We'll sort it out!" "Don't I have my license?" "Yes, you do!" "But don't go to extremes." "Take it smoothly." "Your license is in your hand." "Now you go home." "On foot!" "See?" "I see." "I'll call tomorrow in case you regret it." "No!" "I won't be around, nor the following days." "I got transferred to Paris." "This a leaving present?" " For my most regular pupil!" "Yeah, right." ""Regular"!" "Car Weekly, please." "That's OK." "My pleasure!" "Mom, he's here." "Yes, of course!" "Let's eat!" "Sorry, it won't happen again." "Not if you screw this up!" "My dad's real strict." "Oh, come on, deep down, he must be nice." "His daughter's eyes are so blue!" "You just be careful!" " Don't worry, it'll be OK." "I know I'll like him, so he'll like me!" "Is he a cop?" " No!" "OK, then!" "Ain't nothing worse than a cop!" "Dad?" "I'd like you to meet my boyfriend, Daniel." "You're a doctor?" "Go on." "Knock him dead!" "Pleased to meet you." "I've heard so much about you." "Are you deaf or won't you answer?" "I'm not a doctor." "I'm an apprentice!" "What year?" "1st." "I mean, I'm about to change into 2nd." "2nd year?" "You're not young." " Edmond!" "What?" "I'm just inspecting a new recruit." "Answer!" "Sir, I'm not young, but I've done lots of jobs to feed my family... and pay for my license... studies." "I started when I was 12, so I've aged." "What jobs?" "I drive a taxi... ambulance." "Ambulance!" "I got delayed at the clinic." "It lets me keep my hand in." "Eye in the road, eye on the patient." "2 things at once: you make mistakes!" "Excuse me, sir, but I disagree." "Just look at you." "Oh?" "What do you mean?" "I see a lot of decorations there... proving you've had a successful career." "Then I see Lilly:" "pretty, intelligent, well-educated." "You clearly managed to do 2 things at once." "I drove an ambulance, too, in '59 in Algeria." "Eye on the road, eye on the machine gun!" "See to the injured later." "If they're still alive!" "I'd like to see my roast beef!" "Affirmative!" "I'm starving!" "Forward!" "Now, the endurance test:" "3 hours of war stories!" "I'll slip into neutral and cruise through!" "I hurt you?" " Not at all." "Good." "I heard your hip crack." "It's mine!" " Let's stop." "I'm fine!" "I don't want to hurt you, but I'll be OK." "I'm OK now." "I could've massaged it for you." "But if you're OK." "Fine!" "The surface pain's gone... but deep down, there's a nagging pain, a stiffness." "Maybe a little massage would ease it." "OK, guys, a match to finish, for 5 minutes." "Bow!" "Change partners?" " No." "I really don't want to hurt you." "I'm touched by your concern, Emilien." "Now I warn you, I started, aged 4." "I can teach you a thing or two!" "Your smile could melt a radiator!" "You put me off!" "Real opponents don't smile!" "It's not fair!" "Listen up, you sumos!" "Meeting with the boss in 5 minutes!" "What's up?" "You lost your lenses?" "I can see you well enough to kick your ass!" "Just trying to help!" "You done much judo?" " No." "Only a couple of times." "It's not my sport." "So, what is?" " Karate." "Far more effective!" "Mine's ping-pong." "No good in fights, same principle:" "Spirit of Rising Sun!" "Kon-ichi-wa!" "It's easy." ""Con". "Consummate idiot" like Emilien!" "Thanks!" "Then, "ninny" like..." "Sorry, Pétra." "It's just an example." "And "a" as in "aaaa"!" "Kon-ichi-wa!" "Now, you." "Not bad." " What's it mean?" "It means "hello" in Japanese." "And don't forget it!" "In under an hour, in ol' Marseille we greet Japan's Defence Secretary." "Mr..." "Tefu..." "Techumila." "Mr. Tef..." "Tejus." "Just call him Nip!" "The Nip's from Tokyo." "Before the Franco-Japanese summit after Bastille Day in Paris... he's visiting our charming town." "Known why?" "The climate?" "The sights?" " Sure." "The food?" " The Pastis?" "The soccer match!" "You're a big bunch of nerds!" "Our anti-gang training base!" "The Japs have a problem with the Jacuzzi..." "Yakuza... who are even kidnapping members of the government." "The Defence Secretary visited England, Germany and France." "Let's get one thing clear:" "the Krauts and the Limeys mustn't win the contract." "Let's make this World Cup II!" "I put together a detailed operation which I will now explain." "I called it Operation..." "Ninja!" "He's got no more ammo." "Suddenly... no more ammo!" "Well, that's only natural." "Yeah, only natural." "I turn to Raymond." "Here he is." "I shake him." ""Raymond, your ammo!" I say." "No answer!" "I shake him again!" "Then... he falls sideways." "Dead!" "Terrible!" " My whole unit!" "I'm alone." "Armoured car's on fire, radio's out and my flask's half-empty!" "Oh, no!" "So, then what?" "I prayed!" " Well done!" "That's all I could do." "Only a miracle could save me!" "A miracle!" "We're saved!" "Now what?" "Edmond, the red phone!" "The red phone?" "Excuse me." "General Bertineau speaking." "It's you, Bertrand on the red phone?" "Well done, Daniel." "You'll get dessert!" "My God!" "I completely forgot!" "No problem!" "I'll be there!" "Catastrophe!" "We'll wait." " I'll be 1 hour!" "I want you right now." " Give me 20 seconds!" "The airport, fast!" "That's kinda long!" "Catastrophe!" "Dad!" "You OK?" "You hurt?" "Catastrophe!" "She won't go so good now!" "In 15 minutes I'm to greet Japan's Defence Secretary." "Catastrophe!" "I'll get you there in time." " Impossible!" "Try me, sir!" "Seatbelt, please, Dad." "Is this your ambulance?" " No, a taxi." "My brother loaned it to me." "Save me some dessert." " You can have seconds!" "Let's go." " Sure!" "We're crawling 'cause of these tires, but they'll soon warm up!" "Don't overheat!" "Now look, kid." "This is the new Cortex 500." "The Rolls Royce of speed traps!" "Turn it on." "Instant read-out." "Go to the roadside." "Put your arm out slightly." "You better learn on the old model." "We're on the highway?" " Now I can step on it!" "You must like hospitals!" "Catastrophe!" "Chief!" "We got one!" "A biggie:" "306!" "I think it was a 406." "And not factory-fresh!" "306 km/h, moron!" "Tell others!" "A white taxi at 306 km/h." "I repeat 306 km/h!" "Yup, 306!" "We'll get him!" "You OK, sir?" "It's him!" "I must get there!" "Change of tactics!" "What?" "This isn't it!" "It's a short cut!" "Hold on!" "I have a UFO on Runway 1!" "Yield to aircraft." "We have just landed." "Outside temperature: 95 degrees." "We hope you enjoyed flying with us!" "Excuse me, Captain, a taxi's coming." "I can't hear over the noise!" "I repeat: taxi approaching." "I never ordered a taxi." "Did you?" "No, but I know him." "14 minutes 30 secons!" "Great!" "Bertineau, why the taxi?" "We lost a car." "This guy saved my life." "Con-ninny-a!" "What?" " What you said." "God help me!" "Glad to be here." "Thank you for greeting me in Japanese." "Me, Gibert, protect you during your vacation... uh, stay." "Our Secretary." "Say hi." "This is he." "Dear fellow!" "I'm honoured to meet you." "I'm a member of your security team." "We wish you a nice stay." "You speak very well." "A little." "If I can help in any way, just ask." "Pleased to meet you." "Only the blonde girl speaks Japanese." "I copy." "Go back to base." "Let us offer you a cocktail." "This way." "Does your file say you speak Japanese?" "Below my measurements." "Guess I stopped there." "Do me a favour, son." "See that taxi there?" "I sure do!" "Love to, lady, but I'm busy." "Another time?" "Always in the right place!" " Know that guy?" "Bertineau, head of the Med." "Basin." "Lilly's dad!" " No shit!" "I was there for lunch." "Unbelievable!" " Yeah, I can't stand the army." "You couldn't stand cops." " I still can't." "I can't stand you!" "Well, he seems to like you." "He wants you to come to the cocktail party." "Half cops, half soldiers?" "That's a nightmare!" "Prefer half mechanics, half gas station attendants?" "Come on." "The chat's the same:" "cars, sport, chicks!" "You'll fit in fine." " I'd be ashamed." "Listen." "If Bertineau is Lilly's father, he could end up your father-in-law." "What will he think if you say no?" "One drink, no more." "Martini?" " My sister's name!" "One for the road won't hurt you!" "Domo arigato." " The gateau is good." "Locally made." "Next to the station." "Excuse me." "I'll get you another." "Don't get him too stewed to sign the contract." "No worries, I know what I'm doing." "Just softening him up." "He's nearly done!" "Is your plan ready?" "Sir, it's hearsed and rehearsed to death!" "It's fine-turned to the second." "You're not all as I imagined." "No offence, but a bright 2nd-year medical student..." "I thought you'd be more..." "Pimply?" " Right." "And a slower driver!" "Yes, he's the "fastest" doctor I know." "Well, I'm very grateful." "Gratefully indebted to you!" "Ask me anything, but Lilly's hand!" "'Course not!" "I can't think of anything else." "Valid 1 year, parts and labour!" "Excuse me." " Go ahead." "Emilien, start of Operation Ninja." "Pétra, watch him." " Watch me?" "Friends with cops?" " No, only with one." "Good!" "It's rare." "Most youths are anti-cops... anti-army, anti-everything!" "They want to kill the father figure." "Sir, my patients are waiting." "Wait!" "5 more minutes." "You'll find this very interesting." "Selling the Japs Peugeot?" " Nothing's impossible!" "This is the Cobra." "Specially designed to protect visiting dignitaries." "Titanium bodywork." "The multiple side panels can resist any bullet!" "Missile detectors, front and back!" "Coating:" "Phantom!" "Solid tires!" "It's linked to the Atlas satellite... and if necessary, can be piloted from HQ." "Now, the engine." "Ninja!" "Nice noise for a V12." "V12 engine, twin turbos." "Voice-activated!" "Top speed: 320 km/h!" "Range: 900 km." "From Paris to Marseille." "2 airbags in front, 2 in back, 4 at the sides." "8 in all for maximum protection." "Ladies and gentleman, this car is like France:" "indestructible!" "That's just 'cause we set it to ultra-sensitive." "It's usually on normal!" "See the balloons?" "Useful against thieves!" "Get him out!" "Tell him not to worry." "He needs the bathroom." "Bertrand, go with him." " Yes, sir." "It'll be good as new in no time." "Will he?" "Now who'll drive it?" "Sir, I have a young civilian driver." "He's very good." "I'll vouch for him." "Banco!" "Before your tour of the town, I'll show you our latest computing innovation." "Gimme that!" "Wear this." " It'll cramp my style." "Even a cretin with mitts on could drive this baby!" "Take him away!" " No, it's OK." "Told you!" " Never mind." "No one'll see." "Go on!" "Ninja!" "How do you stop it?" " You just have to say "Nip"." "Ninja!" "The mission's simple." "We prepared a demonstration." "With fake attacks!" "Like the ghost train?" " Yes, so as to impress the Nip." "Above all, don't worry." "Let things happen." "If the Nip..." "Don't play while I'm talking." " You keep saying "Nip"!" "Great!" " Not bad." "Sir, we shall now escort you to your hotel." "Get in!" "Up shit creek again!" "Forward!" "They're here." "On this road." "It's going as planned." "Very good, Katano." "Let me hear them." "Spring Roll, come in." "Hey, Emilien, come in!" "Do you read me?" " Loud 'n' clear." "We just left for the 1st trap." "Be with you in 20 minutes." "OK, 20 minutes to warm up." "What about us?" "What can we do for about 20 minutes?" "I don't know." "Any ideas?" "Yeah, but 20 centim... minutes is too short!" "Oh yeah?" "So, we need an idea we could start now and finish later." "Yes, that would work!" "But..." "I too have an idea." "I'm sure you'll really like it." "Oh yeah?" "It may be the same one." "That'd be marvellous!" "It'd be ideal!" "Go on, you first." "Make the most of these few quiet moments... to learn Japanese!" "It wasn't the same idea." "He won't see much of Marseille." "Sorry, he's suffering from jetlag." "May I ask why your boss is here?" "To sign very big contract and see anti-gang method." "He'll sure see that!" " You know method?" "Sure I do!" "1st, the suspect." "He's probably guilty." "A foreigner is doubly suspect!" "Then there's the guilty, foreign, tanned suspect!" "He's had it!" "If he's tanned, he just sun-bathes and does nothing all day, he's a suspect!" "So, he's guilty." "Faultless logic!" "That boy any good?" "Very good." "A young doctor, friend of my daughter's." "Something tells me they're flirting." "Only natural at their age." " Quite." "To make the guilty party confess, they use questioning!" "Simple!" "They apply a trilogy like Star Wars." "Episode 1:" "Beat him up!" "Good, healthy exercise!" "Episode 2:" "Tax 'em to raise some cash for the Christmas party!" "Episode 3:" "Drink copiously!" "I'm pleased some youngsters still respect our values." "A good son-in-law." " Think so?" "Many French gangs?" "The most dangerous are the heavy mob: 100,000 - strong!" "Easy to spot:" "Always guzzling beer!" "Go toward the port." " My pleasure, chief." "He sounds very polite." " Affirmative." "Courteous, too." "Polite to your face, shaft you from behind!" "Like in the souk." "A big smile as they steal your cash!" "But I've got my eye on him." "Tell me something." "I've not been in the police long, but try me." "What means the word your captain uses: "Nip"?" "Why'd he stop?" "I said to beware!" "What's going on?" "Just a simultaneous translation problem!" "Cut the crap." "We're at the meeting point in... now." "Don't worry!" "General alert." "Shit!" "There's a missile pointing at me." "Missile?" "What missile?" "Atlas:" "Real-time missile diversion." "Unique!" "The Limeys won't get the ball!" "Impressive, but where's it headed?" "Don't worry." "Somewhere far out at sea." "Shit, my boat!" "The high point of our show." "Impressive!" "Very good work, Gibert." "Thank you, sir, I'm so pleased to be able to try out this equipment at last." "Roadhog!" "OK, the coast is clear." "Impressive" " You get used to it." "A regular day." "Your moves are improving, but not your accent." "Spring Roll!" "Copy?" "Just fine." "Did you make it." "I mean, are you here?" "1st attack completed." "Be with you in 5." "Ready?" "Pétra and I were checking a few things out." "A-OK." "Emilien, Gibert here." "I'm counting on you." "You can count on me, Pétra." "I mean: you can count on Pétra!" "Count on Pétra!" "Go!" "Dammit, I told you to warm up!" "We're hot!" "Gibert will kill you guys!" "Go warm up!" "Just off to the little girls' room." "I'll go with you." "You never know." "Can't you read?" "It says "Green light"!" "Get a move on, you fag!" "Oh shit!" "Now turn left." "I repeat left." "Yes, chief." "I repeat, chief!" "He says you drive well." " I'm not moving!" "It freaks me out not to hear the engine speak to me." "Putting in earplugs?" "Do I talk too much?" "Nein!" "It's a miniature ear transmitter." "Brand-new!" "I'm on channel 1." "But how do we talk?" "I know you French can't handle it, but an order isn't to be discussed!" "Yeah, but if you have a problem what do I do?" "Can you hear me?" "1 bang means yes, 2 means no!" "Mind if we keep chatting?" "That's good, 'cause the closed door makes it easier to talk to you." "I don't dare to say things to your face." "Your eyes trouble me." "They're so... so blue!" "What's Spring Roll up to?" " What?" "It's in code." "I just can't find the translation." "When your eyes look at me... wow!" "It's a 1st, or I had my back turned." "Part of method?" " You bet!" "Daniel's method!" "It's good to open my heart to you." "You don't mind too much?" "Should I go on, then?" "I don't get it!" "Have you noticed that I'm much closer to you now?" ""No"?" "Good!" "OK, Pétra, I'll say something you may find shocking." "Here goes." "He'll screw up!" "Well, since Day One, I've known I love you!" "Well played!" " Told you!" "There, I said it!" "Now put me out of my misery:" "Is it mutual?" "So, uh... 1 bang: yes, 2 means no." "Change channels to talk dirty!" "We're working!" "Left here, kid." " Yes, pops!" "He's not one of us." "That's for sure." "He's not one of us." "What're you playing at?" "Go on!" "Ninja!" "Sorry to be so down:" "I smell a trap." "Smell a trap?" "I don't smell a thing." "Do you, sir?" "Strange how those trucks are parked." "Just room for 1 car!" "No, there's no trap." "I checked the map." "No trap here." "Drive on!" " If you say so." "I should know." "Well, I never!" "A trap!" "What's he up to?" "What page?" "That's not on my list." "Hats off!" "Shit!" "Glad it's not my taxi!" "What happened?" "Where's the Nip?" "Some Ninjas... came, and the Secretary went." "What?" "He didn't fly away?" "He did!" "At that speed, he must be on his way to Mars!" "Ask Atlas." "It must've spotted him!" "General alert!" "Stop!" "Police!" "Shit!" "Complex town, huh?" "Small streets!" "The jails are no bigger!" "Lie down there!" "I'm crack shot, so no tricks!" "You speak French?" "Me warn you: me shoot!" "Spread out!" "Is that how you wanna play it?" "All right!" "Now where are they?" "They didn't fly away, too?" "Where's Emilien?" "Emilien!" "I reckon he's near the garbage." "I was this close to getting 'em, but I was outnumbered." "They took the Secretary!" " Which one?" "The Nip, not ours." "It's a disaster!" "Yeah, and they got Pétra, too." "Good." "She speaks Japanese, so he'll be less alone." "Lilly, I'm coming." "Your dad made me stay!" "But it's been 2 hours." "I'm hot all over." "All over?" " Yeah, all over!" "I'll be on fire soon." "I'm coming." "Watch a documentary - it'll calm you down!" "I'll be 5 minutes." " Too long!" "4 minutes!" "It's my fault for leaving her in the john!" "You shoulda gone with her." " I thought of that." "I did." "But..." "Finished scratching about yet?" "There were indeed cars here. 3 of them." "You read Sherlock Holmes to deduce that?" "Don't you have any clues to get us started?" "We'll analyze the tire samples at the lab." "That'll tell us more." "They'll have time to swim back to Tokyo!" "Thanks for everything, but I need my taxi now." "Want your convertible?" "We're in shit!" "These clowns are shaving the road!" "Please help us find a clue." "Look, Lilly's on fire." "She might burn herself." "They got my girl." "Give me 2 minutes of your time." "Take a look, then I'll handle it." "From below, I saw 3 black Mitsubishis." "A new model." "Tires straight from Japan." " How d'you know?" "Smell it." " Fish." "Meaning?" " A restaurant?" "You got fish oil for brains?" "Restaurants and ports!" "They were on a boat from Japan!" " So, that's why they smell of fish!" "See?" "Now, are they stolen cars?" " Easy!" "Alain!" " I'm onto it." "OK, you put your tweezers down." "On Monday morning, you'll get a whistle and be put on traffic duty!" "Idiots!" "Nothing stolen from the port." "Bingo!" " What?" "It just means you were wrong." "Why wasn't the theft declared?" "'Cause they use the warehouse as a base!" "You can be real smart!" "General alert!" " No, Emilien." "That's always my line." "Explain it to me once more." "I'm on my way!" "You watching TV?" "No, I stopped." "There was a report on animal sex." "I burned the rug!" "Lilly's worried." "Give me that." "Tell your mom it's OK, but I need to commandeer your friend." "He did a great job." "Good recruit." "He'll bring me home." "You can say goodnight then." "Bye, hon." "C'mon, let's go." "The mission's not over." "What's Gibert up to?" "I dunno." "He's been in the john for ages, making weird noises." "What's up?" " I can't tell you." "It's... too horrible!" "They won't come." " What?" "I think this was their 1st base." "They're gone." "Long gone." "Suspect approaching." "Asian male." "They always return to the crime scene!" "Police Academy, lesson 1!" "Positions!" "Captain?" "Suspects approaching front door." "Perfect!" "I'm ready for 'em!" "Hey, you sure about this?" "What?" "It's the heist of the century!" "There's a mountain of VCRs, boxed and awaiting delivery!" "They're about to break in." "We got 'em!" " Emilien!" "You break in to your home?" "Sure." " Oh yeah?" "Well, no." "Uh-oh!" "Chief, are you gonna...?" "I like to stay close to my men." "Some action won't hurt me." "Just like in the old days!" "It was long ago." " The memory is distant." "But the reflexes... are still intact!" "Believe me." "Thanks!" "Sure there's no cops?" " Relax, dammit!" "There's no one here!" "They're all watching the game." "Every cop's in front of a TV." "Ready to attack?" "Wait for my signal." "You worry me." "It's a long way down." "It's OK." "Tie the knot." "I'll do the rest." "Uh-oh." "See?" "They're all at the match, like I said!" "Attack!" "Shit!" "Emilien?" " OK, chief." "Bonzai!" "Someone being knifed?" "The knot's all right." " Yeah." "Maybe the rope." "You got the wrong one." " You're right." "Ambulance!" "Now!" "I should never have left her or let him down." "That's enough crying over spilled milk." "It won't bring her back." "Think!" "I am!" "But we don't have a single lead to go on!" "Ask the right questions." "Why didn't the Yakuza kill him at once?" " They need him?" "Why?" "Did they ask for a ransom?" " No." "Why kidnap him here?" "They must have had a good reason." "Why's he going to Paris?" "To sign contracts." "Security, trains, army, nuclear." "There!" "Maybe they want to stop him." "Makes no sense." "Why do that?" "He's right." "Yuki Tsumoto wants to stop him." "I know you." "Weren't you an air hostess before?" "I'm here to protect the Secretary." "I'm in counter-espionage." "Funny!" "I too am." "I'm in counter-espionage." "That's Daniel." " Intern." "I'm learning to be stupid!" "Clever!" "Who's this Yuki Tsumoto?" "Yakuza." "Controls the north." "Powerful and conservative." "Refuses airplanes, trains, nuclear power." "As France is keen to sell, he's taking steps." "The Secretary won't sign, nor will Japan ever again!" "Tsumoto sent over 2 masters in hypnosis." "The Secretary, when the time is right will shoot someone." "Perhaps the President." "France will sever all diplomatic ties for years?" "Exactly." " Crazy!" "We must free your friend and the Secretary before 11." "I better tell my boss." " The cripple or Sleeping Beauty?" "Listen." "You both got someone to save." "As we're in a rush, we better not disturb the powers that be." "No?" " Right!" "No Nip'll beat us!" "Pardon me!" "Where do we start?" "First, can you find them in Paris?" " No way!" "Easy!" "Child's play!" "Thanks, Joe." "You saved my life!" "See you soon, pal." "They're hiding out in southern Paris." "Sure it's her?" "Uh, them!" "3 black Mitsubishis with a blonde." "OK?" "To the airport!" " No plane for 3 hours." "We can't wait." "We must get there right away!" "Get up!" "It's war!" "Men!" " It's me, Daniel!" "The troops?" " Wiped out!" "Just us to save the day." "You're indebted to me." " Affirmative!" "I need your help." "Shit!" "What 're they up to?" "Cool, pal!" "Way to go!" "I really hope you know what you're doing, 'cause I don't!" "Got a better idea?" " Right now?" "No." "Well, think fast!" "I got it!" "Let me out." " Too late!" "Are you cool?" "You bet!" "Cool as ice!" "Just shout, OK?" "OK, I'm shouting!" "We lost a parachute!" "There are 3. 1 or 2 always screw up!" "Oh, right!" "Got your license?" " Yes." "So, take over here." "C'mon, move!" "I'll steer us." " Where do I go?" "Straight ahead." "Straight ahead?" "OK!" "Come on, just relax." "Be more zen." "That's good." "Real good." "Oh Lilly, you OK?" "Who's the warbler?" " Air hostess." "No, a nurse!" "You in a massage parlour?" " No way, Lilly!" "We're in the sky." "Your dad's guiding us." "Emilien's steering, I'm fixing a parachute... the nurse is singing to calm us down!" "You smoke a tree?" "!" "I'm trying to save Pétra and Japan's Secretary!" "I'll call you when we land!" "Goddammit!" "You OK, hon?" " Just fine!" "What a doubter!" "Try to turn left a bit." "Now, turn left." "I repeat, left." "Hi there!" "It's OK!" "Stay calm!" "Marseille Police!" "Move!" "You know them?" " Yeah." "An old pupil." "Well, I'll walk home." "OK, Lionel?" " Jacques, Mr. Coutta." "Hello there." "All set, Coutta?" " Just Japan's Secretary to come." "I see her." "God, she's lovely!" "I mean, she looks well." "The Secretary?" " Fine." "He's exercising." "Maybe we should get 'em back." " But we must warn your friend." "It won't be easy." "What a jerk I am!" " Really?" "Her earphone!" "Are you ready to kill?" "You hear me?" "We're not far away." "Get up... and turn around." "Show me your hands." "What's going on?" " It's not me." "You suck!" " So do you!" "Sit down." "We're coming." "Easy to say!" " I got a plan." "That's what worries me!" "You hear only what I tell you." "Only what I tell you." "You obey me." "You do only what I tell you." "I wanna go home!" "'Cause it's cold and I'm getting sick." "You're going to sleep." "Raise your arms." "Hey, it's my turn now!" "Come on!" "I'm not bad at hypnosis!" "Sit!" "Good!" "Now lie down!" "Very, very good!" "Now sleep!" "Freeze or you'll sleep, too!" "OK, I'll cover you." "Hey, girls, what're you doing?" "No need." "I had 'em covered." "It's not loaded." "What's that?" "How come?" "It was me." "I emptied the clip yesterday." "So... it was never loaded?" "So you wouldn't get hurt." "I'm late." "Help me out!" "It's OK, I'll manage." "Jump in there!" "Are you sure?" "I don't wanna fall down!" "Catch those clowns!" "Fancy some sushi?" "No exit, Daniel!" "Nips closing in!" "One less!" "We'll get out here." "We're too heavy." "They're good!" "Ask your colleagues to help out." "Forget it." "Paris Police hate us." "You just never asked 'em politely!" "What the... ?" "You faggots not at the parade?" "Soldiers ain't your thing?" "You'd rather stay home and gobble knobs?" "How 'bout a love parade?" "Catch me if you can!" "You went a bit far!" " Don't worry!" "They love it!" "Catch him alive!" "I'll kill him myself!" "Where are you?" "Where's Trocadero?" "Change at Chatelet!" "A bus!" "Oh, the Eiffel Tower!" "Off the grass!" "Straight on!" "OK!" "There's one!" "Get the taxi!" "Kamikaze!" " Kami what?" "I can't shake 'em!" "We're too heavy!" "I'll get out!" " No, try again!" "I can't!" "Call the General." " General!" "Loud 'n clear!" "How's your tour going?" "Whizzing by!" "He's gotta block the Dauphine tunnel." "We'll trap 'em!" "Give me 5 minutes." "Picard?" "Bertineau here." " Sir!" "Got a spare tank or two?" " Sure I have." "He better hurry up!" "We're there." "What's he up to?" "OK, sir, the tunnel is blocked." "4 mins. 32 secs." "Well done, sir." " Hang on!" "I don't wanna play!" " You wanna get shot down?" "I don't wanna hit a tank!" "I wanna spend time with Pétra before I die!" "I'm taking you to Heaven!" "I wanna stay here on Earth!" "Learn to drive, you moron!" "You scared me again!" "Maybe one day you'll trust me!" "You're wonderful." "Be his driver in Japan." "Thanks, but right now, I just want to go home." "Yeah, we're going home." "Want dropping off somewhere?" "Not the TV!" "Just 5 minutes." "I want to see your father." "It looks like Daniel's taxi!" "Well, that's brand-new." "A stealth taxi." "I'll drop you at the grandstand." "This place freaks me out."

"250)}A brush against the freckles that I hated oh so much... and then I heave a little sigh." "250)}The heavyweight love that I once shared with you... 250)}..." "Miraculously dissolved with the sugar cube." "250)}The little prick that I feel on my bosom that has shrunken... 250)}...from the little thorn really hurts me now." "250)}I guess I cannot trust those... 250)}...silly horoscopes after all... 250)}I wonder what it would be like... 250)}...if we could go further away... right?" "250)}I'd be so happy... 250)}...just because of that!" "250)}Memories I have are always beautiful in my mind." "250)}But they can't feed me:" "they can't fill up my stomach." "250)}In reality tonight was supposed to be somber." "250)}I really do wonder why... 250)}I just can't see how all of the tears were streaming down his face that night." "2000)}I just can't see it anymore... 473)\cH3541B8}D-YFI" "335)}Wandering Samurai 178)}Rurouni Kenshin" "Yummy toasted rice!" "The best tumblers in Japan!" "it's the biggest thing from the West!" "hurry up!" "Over here!" "that there is not." "The snake!" "Look!" "Rice skewers!" "Mermaid!" "all you're going for is the food!" "all you're going for is the food!" "You're doing it too!" "But really..." "You're doing it too!" "But really..." "But really..." "What's wrong with that?" "stop arguing!" "that it is..." "Of course!" "The Sumida River neighborhood is now a landmark!" "What is the matter with you two?" "look there!" "58)\cH4A5867\frz4.192}Haunted House" "This looks good!" "Let's go inside this place!" "It has to be some little trick to fool kids!" "But you're a kid too!" "Wha... let's go in!" "Let's go in!" "378)\frz0.027}Lightning Beast" "T-The wing moved..." "So a lightning monster does exist..." "What?" "It is a rokuro-kubi monster." "A fox-woman!" "A raccoon-man!" "A tengu!" "They seem to be having fun..." "I think they're just scared." "I see..." "So that's how it worked... they put fake wings on a boar and were pulling it with a string." "They sure are tricks to fool kids." "That's how it's usually done." "it seems perfect for Kaoru and the girls." "that it does." "The tengu got beaten up..." "I feel sorry for him." "It's because..." "I feel sorry for him." "It's because he scared helpless little girls..." "I'm gonna quit this business now... 422)\cHFFFFF5}Blast to Your Dream The Adventure of Marimo the Flying Bullet" "3570)}Ebisu cannon circus what's this?" "So many people..." "Let's take a look!" "Maybe it's worth watching!" "is it?" "there are virtually no customers here!" "It's been like this ever since that circus appeared across the way." "that cannon girl!" "She took all our customers out from under our feet!" "now!" "Thank you very much for coming today to our Ebisu Cannon Circus!" "witness this!" "Thanks for waiting." "I will now show you the human cannonball." "please applaud!" "She's cute!" "That girl looks like she's Yahiko's age!" "that it does." "I wonder if she'll be all right... that it is." "but it's no good if there's too little... here we go." "One!" "Two!" "Three!" "Meiji cannon girl!" "It doesn't go well unless the father and daughter synchronize perfectly." "that it is." "she flew!" "hey!" "Outta the way!" "Go home!" "dammit!" "Those guys... why are you stopping him?" "that you should." "what do you mean by this?" "I was worried whether or not your business was doing well." "you know." "You don't have to worry about that at all." "I became independent through a perfectly legal contract." "but I don't want you to forget..." "You still owe us the money that you borrowed when you went independent." "I will return the money." "and the rest tomorrow!" "I see." "Then it is all right." "The promise was that you'd return the money before tomorrow night." "but if you can't pay up you will return to our Circus without complaints." "Let's go back!" "Yeah!" "What are you doing?" "I'll be waiting for you to come with the money tonight." "you know." "terribly sorry about that!" "You have to be careful..." "What a bunch of ruthless guys!" "go beat them up now!" "Yahiko!" "He's not here?" "He's over there!" "When in the world did..." "U-Uh..." "I'm Yahiko Myojin!" "to fly from that cannon!" "I'm impressed!" "I'm Marimo..." "Little Yahiko!" "Stop it with the "little" thing!" "So then what... right?" "It's nothing like that!" "I'm just..." "You don't have to hide it!" "Along with little Tsubame from Akabeko you sure fall for girls easily!" "Yahiko?" "On a walk." "it might be good for you to feel the night breeze and cool off!" "That was such a weak excuse." "just as I thought... that he is." "It is Yahiko's masculinity at work." "Watch out!" "that money..." "Wait!" "Dad!" "Dad!" "Someone!" "You did this to my dad..." "I don't know about that..." "Someone!" "Let go of me!" "My dad..." "You can't perform tomorrow anyway." "You have to come back to Sumidaya!" "Let go of her!" "Little Yahiko!" "You don't need to say "little"!" "Y-You little... first apprentice..." "Yahiko Myojin!" "You little..." "Shit!" "I-I'll get you back for this!" "wait!" "wait!" "Dad is..." "Dad is under all of this!" "What?" "He won't be able to move for a while." "I have to get the money back..." "Dad!" "Sumidaya will pretend not to know anything!" "Dad..." "No!" "I have to hold a performance tomorrow because if we don't have it..." "Y-You're right..." "You don't have to return it!" "They were the ones responsible for toppling the lumber!" "W-We have no evidence..." "They'll say it was an accident." "Sumidaya is someone who does such things." "We went independent because Mr. Sumidaya kept doing horrible things..." "Why do you let such a guy keep running around?" "F-First things first the performance..." "I told you that it's impossible!" "I'll do it by myself." "Teach me how to make the gunpowder..." "It's impossible for an ordinary person!" "It's all right!" "I can do it!" "It's too dangerous!" "you could blow your feet off!" "But..." "I can't let you face such a dangerous situation!" "so..." "It's all right." "All we have to do is go back to Sumidaya." "Is mixing gunpowder similar to mixing medicine?" "maybe I can do it." "I smell blood..." "You like it?" "It's better than the smell of apples..." "Yeah..." "I especially love blood from someone I've slashed..." "How about you?" "Me?" "I have no interest in blood... looking at your thin little neck..." "I just want to crush it with a good squeeze!" "you can if you'll be my target." "There really are no customers coming here!" "But that will end today." "so I'm sure they can't have a performance today!" "That means..." "I was in the wrong." "I'm sure that's how they will come crying back to us." "I'm not sure about that..." "I can't rest assured yet!" "But that girl can't shoot the cannon by herself!" "Such a spirited girl would be one to do it all by herself." "We should be extra cautious." "O-Okay... and let us handle it... the dear cannon girl wouldn't be much use afterwards!" "come all!" "It's not something you can see just anywhere!" "where a cute little girl goes flying with a boom!" "Just as I thought." "But this is it!" "You sure are working hard." "Just watch!" "We'll pull this off perfectly!" "By the way..." "Where is this girl?" "What did you come here for?" "Of course I came here to watch the cannon girl." "Maybe it's not that... that we are." "It's the same thing..." "So you're here to make fun of me after all." "Do I look like a guy who would do that?" "You do!" "Something's wrong!" "Yahiko!" "Marimo?" "The gunpowder..." "The gunpowder is missing!" "Someone stole it!" "What should we do?" "What now?" "We already have a bunch of customers inside..." "A fireworks place..." "This neighborhood has many places that make fireworks." "that you can." "That's it!" "I'll go with you!" "Yahiko!" "Will they make it in time?" "the crowd will get rowdy." "we'll hold the audience!" "We have to do it!" "I-It is a little embarrassing..." "Why me?" "Come on!" "Hurry up and start already!" "We paid money to see this!" "Thank you for waiting." "She's going all out!" "that she is." "Thank you very much for coming here to the Ebisu Cannon Circus today!" "we will have a special presentation!" "I wonder if they'll be all right..." "They'll be all right!" "Ken is with them!" "Y-You're right... 137)}Gunpowder Formula umbrella-spinning and ball-riding featuring..." "Sometarou and Somenosuke Himura!" "Sometarou?" "Sometarou and Somenosuke Himura!" "here we go!" "I-I'm really going to do this?" "there's a way!" "do your best!" "It's like a boat that I'm halfway on... that I will... hold on!" "Big Brother!" "S-Sano!" "H-Hurry!" "Kenshin!" "Kenshin!" "Kenshin!" "Kenshin!" "Kenshin!" "They're all laughing!" "254)}Somenosuke that I am." "Somenosuke!" "Do some more!" "you're awesome!" "Thanks!" "Thank you!" "We have to hurry!" "Yeah!" "Marimo... the preparation of the target has been completed!" "wait!" "Why am I doing this?" "Don't ask me..." "They are Miss Kaoru's instructions..." "What if she hits me?" "correct?" "You bastard!" "are you confident about this?" "Nope!" "Kenshin!" "Hey..." "S-Sano..." "There's blood..." "Kenshin!" "Catch him!" "Hurry!" "I will!" "wait..." "You think I'll wait?" "we only need a moment from you..." "No way!" "Isn't it time for the human cannonball yet?" "yeah!" "Hurry up and start!" "hurry..." "Outta the way!" "Yahiko!" "It's dangerous if you don't pay attention when you run." "Y-You..." "How about you give us that bag you got there?" "You again!" "Stop muttering and give that to us!" "Yahiko." "Y-Yeah... don't let them have the gunpowder!" "Alcohol... drink if you drink..." "Enough already!" "This is boring!" "...watch out for fires watch out for fires one... stop that stupid song!" "Where's the human cannonball?" "give us our money back!" "yeah!" "Hurry up and start!" "We came here to watch the human cannonball!" "Guess this is it..." "What?" "I was pretty confident about the kurodabushi song..." "Kenshin!" "Yahiko!" "Those guys..." "Kenshin!" "I'm leaving the rest to you!" "that you should!" "This is getting more fun!" "It would have been better if you surrendered to us..." "I don't care anymore!" "I'll make sure you can't perform ever again!" "Soubei Sumidaya!" "He sure is up to no good." "I guess I have no choice!" "Sano!" "Hey now!" "I can slay a man for the first time in a while..." "I'll skewer him!" "Let me break his bones... that they are not..." "Don't take these three too lightly." "You know that Imperialist corpse that was floating down the Sumida River?" "The guys responsible for that..." "Keep quiet!" "that I do..." "Kenshin!" "This is supposed to be a show!" "Use this!" "Sorry to keep you waiting." "we'll show you the secrets of the Hiten Mitsurugi Style presented by Somenosuke Himura!" "Hiten Mitsurugi Style..." "Dance of the Umbrella!" "that I will!" "Such a thing exists?" "Hiten Mitsurugi Style..." "Umbrella Spin!" "That was close..." "Hiten Mitsurugi Style..." "Ball Throw!" "go!" "You're doing great!" "the cannon!" "Why did he just charge straight forward?" "Is he a boar or something?" "You idiot!" "Hiten Mitsurugi Style..." "Boar Evasion." "get a hold of him!" "Thanks!" "the rope!" "Yeah!" "It's finally my turn." "You're not going to draw your sword?" "that it is." "Enough of that!" "Hurry up and get him!" "So he says!" "Come on!" "All right!" "What?" "Hiten Mitsurugi Style..." "Umbrella Drop!" "He's not human!" "I won't let you escape!" "twinkling brightly..." "He's getting away!" "I won't let that happen!" "Here we go!" "All ready!" "We did it!" "cannon girl!" "you're so powerful!" "you're so cute!" "This is kinda amazing!" "that it does..." "My popularity is something else!" "this is amazing!" "Soubei Sumidaya!" "This man here has testified to all of your crimes!" "Don't move!" "that it does." "the crowd is really happy about this..." "Do you want to continue performing with us?" "and I'm good at throwing daggers." "Right?" "you two!" "that you should!" "What are you saying?" "It'll all be settled if you stay back there!" "That is a little risky..." "Idiots!" "250)}When your heart is shaken about with tears... 250)}What should I be doing to help you out?" "250)}Even looking up at the sky... 250)}My heart hurts as much as yours." "250)}Something that you don't have to get hurt over... 250)}Everyone accidentally feels... 250)}Just like the times when you're surprised... 250)}...by how cold the water really is." "just being here right next to you... and nothing else... anytime... whenever you need it." "dreams will someday be reality... 250)}Just for you and only for you... because deep inside that heart of yours... 250)}...every piece of sadness turns to wings... 250)}...for you to fly."

"Hills and water make for a lovely scene mirrored in undulating waves of green." "Wafting in the air are melodies glad and the fragrance of beauties brightly clad." "The Jiangnan scholar, Tang Bohu by name, has no care for either fortune or fame;" "he only delights in poetry and song on his idyllic roamings all day long." "Make way...stand aside..." "Lady Hua is here to offer prayers." "They say her four maids are all beauties." "They say her four maids are all beauties." "Here they come." "It should be them." "Wow, how beautiful!" "Make way...stand aside..." "Stand aside..." "Madam, please take some tea inside." "Autumn Fragrance." "Yes ma'am." "You should pray for Buddha's blessing too." "Come inside after you've finished." "Yes ma'am." "Autumn Fragrance." "Buddha on high, may the moon be ever constant, may flowers ever bloom," "may the beauties among those dressed in green be matched with imperial scholars." "May the moon be full and flowers bloom, may the pretty maid marry a handsome lad." "How dare you take advantage of our sister Autumn Fragrance!" "If our mistress finds out about it, she'll have you beaten for sure!" "Forget it." "Let's go." "I've seen countless lovely women, but never one such as stunning as she!" "Her movements so graceful, her almond eyes so beautiful and cold, so beautiful and cold." "Make way..." "Stand aside..." "Bring the palanquin over here..." "Sister Autumn Fragrance." "Spring hills are her smiles, her brow speaks;" "autumn waters make her soul, jade her bones." "Let's go." "This smiling glance as she departs has sucked the scholar's soul away!" "His soul is flown, his soul is flown, the soul of Tang the scholar's flown!" "Chasing her to the river bank he sees the boat carry her away." "If only his own feet could turn into boats!" "Whose hand is it that casts the net?" "Whose back carries a load of leaves?" "Who carries the hoe smilingly?" "Who reads by lamp light until midnight?" "The fisherman it is who casts the net, the woodcutter it is who carries the load;" "the farmer carries the hoe smilingly, the scholar reads by lamplight till midnight." "Boatman, please row over here." "I need to borrow your boat at once." "What?" "My boat's not for borrowing!" "I need it to make my living." "If I lend it to you, what will I live on?" "Brother, I said "borrow" out of politeness." "Rest assured I'll pay for your services." "Please row over here at once." "Very well, I'm coming." "Please hurry up, would you?" "Take it easy." "What's the hurry?" "Wait till the boat pulls up." "There's no point being impatient." "Hop in." "Careful!" "Be careful!" "Look at you." "What's the hurry?" "It's no joke if you fall in." "Sit tight." "Sit tight." "Sorry." "I have urgent business." "I need to catch up with the boat ahead." "That's Lady Hua of Dongting Town, come to Hangzhou to offer prayers." "They're going back to Huqiu now." "Sir." "If not by day, I'll catch up by night." "Sit tight." "All right, all right." "Sir, are you related to the Huas?" "Yes." "You're related by marriage?" "I'm her nephew." "Oh, nephew." "Please hurry up." "Shall I sing for you, sir?" "You can sing?" "Of course." "Listen." "All right, all right." "Sing a bit more when we draw near." "Singing more means more tips!" "Very well." "As long as you sing well." "Thank you sir!" "But you have to sing the words I tell you." "As long as I'm paid, I'll sing anything!" "In which season do flowers bloom?" "Which flower is fragrant without pain?" "In spring the peach blossoms bloom red, a pity the spring breeze scatters them all." "In summer lotuses bloom in the pond, a pity all hollow are their stalks." "In winter the narcissus by hand is raised, a pity its beauty never last long." "Only the Autumn Fragrance of the osmanthus, neither hot nor cold, warms the breeze." "Night and day I think of Autumn Fragrance." "How can I not lose my soul, lose my soul?" "The boy is entreating at the bow, the girl is inside feeling annoyed;" "Autumn Fragrance is top of the household;" "who dares to call her repeatedly?" "Deliberately throwing out a basin of water, she opens the window to take a look -- and so falls into the scholar's trap which lures the goddess from her chamber." "It's the youth who knelt upon her skirt;" "unaware he's soaked through and through." "Feeling sorry, she smiles again." "Sir, it's raining." "It's raining?" "Here they come." "Here they come." "Here they come." "A hard trip, my dear?" "A safe one, by your grace, my lord." "Go inside for a rest." "Yes." "Greetings, mother-in-law." "At ease, at ease." "Where's Autumn Fragrance?" "She's taking care of the luggage at the pier." "Brother, she's still on the pier." "Bring it over." "That's the lot." "Ask them to carry it back." "Yes yes." "Quickly!" "Quickly!" "Miss Autumn Fragrance." "For sprinkling me with fresh dew" "I've come to express my thanks." "Go." "Sir, you can't just leave." "You haven't paid me yet." "How much do I owe you?" "How much?" "The boat fare, the singing, tea money..." "It's five taels exactly." "I was in such a hurry I forgot my purse." "What?" "Don't try to run!" "You'll be paid, don't worry." "I know you'll pay me." "So give me the money." "I've things to do." "Why don't we settle it in the teahouse?" "Sure." "As long as I'm paid, anywhere's fine." "Let's go." "You first." "It's not as if you can run away." "Go pawn this fan." "It should bring you 20 taels." "Sir, by the heavens, don't tease a simple man." "How can a fan be worth 20 taels?" "Don't worry." "Just go pawn it." "I'll be waiting here for you." "I need the change to pay the bill." "All right." "I'll give it a try." "Don't run away!" "If you run, I'll find you." "Fine." "Proprietor, please watch him for me." "If he runs, you'll have to pay me." "Who's there, acting so suspiciously?" "Are you trying to steal something?" "Come out." "What do you want?" "I... want to pawn this fan." "How can you pawn a fan?" "Please take a look first." "If it can't be pawned, just give it back to me." "It's not even ivory." "This fan's worth a lot." "How much do you want for it?" "Tw..." "Two.." "Twenty taels?" "Yes!" "Twenty taels!" "Write it down." "One fan, 20 taels." "It's really worth 20 taels!" "Old sir." "Who did the painting on this fan?" "Don't you know?" "The painting's by Tang Yin." "Tang Yin?" "Who's Tang Yin?" "Tang Bohu, the foremost scholar in Jiangnan." "What?" "He's Tang Bohu?" "Hey, don't you want your money?" "Oh, yes yes." "Bring me more of his paintings!" "No problem!" "He and I are pals!" "The threshold of nobility is hard to cross, meeting the beauty requires planning." "Loitering outside again and again, how does he open the Hua mansion doors?" "Disguising himself as a poor lad, he moans and groans, moans and groans." "Don't be crying here!" "This is the Grand Tutor's mansion." "Go away." "There's no need for that." "I'm going." "I'm going to the next world." "What grieves you so, little brother?" "I left my home to be with relatives, but met up with bandits instead." "My valuables have all been taken;" "how shall I continue my journey?" "I'm now in such dire straits, death is my only way out." "Come back, little brother." "You shouldn't think such dark thoughts." "There's always a way out." "I'm Wang Jun. We'll figure something out." "You seem a decent sort." "Are you educated?" "Yes, I've had a few years' schooling." "Good." "Let's have a talk." "Very well." "Please." "You're too young to think of death." "There's always a way to go on." "We're in need of a pageboy for day duty in the Grand Tutor's study." "Are you up to the job?" "Yes." "Thank you very much." "You need a guarantor." "Do you have one?" "where would one such as I find a guarantor?" "Then what shall we do?" "You need one for the Grand Tutor's mansion." "They won't take you on without a guarantor." "Uncle, you can be my guarantor." "Uncle, please accept my request." "Get up, get up." "T ell him to come in." "Yes, My Lord." "Come in." "His Lordship says yes." "Greetings, My Lord." "Greetings, My Lord." "You're Wang Jon's nephew?" "Yes, My Lord." "You may stand up." "Thank you, My Lord." "I'm taking you on as a pageboy to accompany my two sons in their studies." "You'll be Hua An." "How's 3 years at 50 taels?" "Thank his Lordship." "Thank you, My Lord." "Can you write out your own contract?" "Yes." "Take him out to write it." "Yes, sir." "Then give him 5 taels." "Yes, sir." "Hua Ping, take our new pageboy Hua An... to pay his respect to my Lady later." "How foolish is our scholar, selling himself to the Grand Tutor!" "For the sake of pursuing a beauty, he's forgotten all complications!" "He knows one daughter-in-law's father, and is nephew to another's mother." "If they see Tang Bohu here, how will he explain it all?" "Hua An, I hear my Lord thinks highly of you." "Serve well and you'll be rewarded." "Thank you, My Lady." "Take Hua An to see my daughters-in-law." "Yes, Ma'am." "Haven't I seen him somewhere before?" "Brother Hua An, let's go." "Thank you, My Lady." "In the West Wing, the 2nd Lady ponders:" "Autumn Fragrance told me this morning she met a suitor at Huqiu whose description matches that" "of my cousin Tang Bohu." "My cousin has always been a ladies' man." "Might father-in-law's new pageboy turn out to be him?" "If it's him, it'd be awkward for me." "If it's really him" "I'll unmask him and tell him to go home." "One obstacle after another, about to meet his cousin in the West Wing." "She's not one to be dealt with so easily;" "how will he get through, get through?" "Last year I declined to give her a painting and she must bear me a grudge still;" "if only she wouldn't summon me" "I'll offer prayers and incense!" "Second Lady." "What is it?" "The new page Hua An pays his respects." "Send him in." "2nd Lady, whenever male servants came you never saw them before." "This is an exception." "I want to see what he looks like." "Yes ma'am." "Hua An." "Come upstairs." "Hua An, pay your respects to the 2nd Lady." "Greetings, 2nd Lady." "How ill mannered!" "Kneel down!" "Kneel closer." "Moon, you may go now." "Yes, my Lady." "Hua an, are you a native of Suzhou?" "Yes." "But I'm from the countryside." "I'm not asking where you live." "What's your real name?" "Kang Xuan." "Shiftiness is a common problem." "It's a problem with you too." "Stand up and answer me." "I dare not." "I give you permission." "Thank you, Second Lady." "You're so young." "Why come here to be a servant?" "Second Lady, I beg your indulgence." "You're pathetic, Hua An." "I know what you came here for." "Autumn night, "Fragrance" of lotuses." "It's a virtue to help others in their quest;" "A Grand Tutor's house is no trivial place, with rules that are strict and harsh." "The osmanthus' fragrance is unattainable." "You should know that and retreat." "You cause me to lose face as well by being a slave rather than a scholar." "You always were clever, cousin." "You saw through at once my purpose here, and disclosed in a line of verse that I came for Autumn Fragrance." "I wish you could lend a helping hand." "I beg of you, Second Lady." "Lady, you are so magnanimous, you will forgive where I was wrong." "I'll do a painting for you next year." "If you want 4 panels, I'll do 8!" "Who needs you to paint?" "Who needs 8 panels?" "I only want you to go home." "I don't want you to drag me into trouble." "Don't worry, Second lady." "I won't get you involved." "As long as you don't give me away" "I'll go once I marry Autumn Fragrance." "The First Young Master is a boor," "and the Second Young Master's silly." "They care nothing for books and learning, but laze around the livelong day" "having dreams about Autumn Fragrance." "You think of her and so do I, we think of Autumn Fragrance night and day," "every moment we think of Autumn Fragrance." "Do you know him, brother?" "He's the replacement teacher?" "He's not dressed like a teacher." "He's wearing servants' clothes." "I'll go ask him." "Where are you from?" "I'm from where I'm from." "You're from where you're from?" "What have you come here for?" "I'm here to accompany you two Young Masters." "So you're here to teach us the classics?" "I'm not here to teach you the classics, but if you want me to do so," "I'd be happy to oblige as well." "Brother, come here." "We were fooled." "He's the new pageboy." "How dare you, you rude servant!" "I'm the First Young Master of the house!" "Where are your manners?" "I'll teach you a lesson." "Damned slave!" "You dare hit my brother?" "I'll show you!" "Brother, you hit me instead!" "Sorry!" "Sorry!" "Young Masters, His Lordship bid me come." "My name's Hua An, I'm here to attend you in your morning sessions in the Study." "Hua An, what can you do in the Study?" "I can do a lot." "Really?" "Do tell." "I can play music, I can burn incense," "I can play chess and write literature." "I can also make verse and play the piece "Phoenix Seeking Mate"." "I can paint landscapes and portraits." "I can play various wind instruments." "I can tell fortunes, and lastly," "I can steal the hearts from women." "How multi-talented!" "If you can tell fortunes, can you tell what's my heart's secret?" "Your heart's secret is..." "Tell me." "The First Master has Fragrance in his heart." "Fragrance is on his lips, and in his dreams." "You really are psychic!" "What about me?" "What's in my heart?" "The 2nd Master also thinks of Fragrance." "Right again!" "Who's this Fragrance?" "The one you think of is Autumn Fragrance." "Willows brush the cheek in the spring breeze, butterflies flutter by in pairs;" "the good times and years pass by, and I've yet to meet the perfect man." "I waste my youth in the kitchen, dreaming of the bridal dress." "A pomegranate that no one admires," "I can only sigh and pity myself." "Sister Pomegranate, what's the matter?" "I feel stressed." "Hasn't Hua Ming been to see you today?" "Who cares if he comes or not?" "You don't mean that!" "Pomegranate, I've something to tell you." "His Lordship's hired a new pageboy, Hua An." "He's very handsome and talented!" "Really?" "I'd like to see what he's like." "Where did you see him?" "When he paid his respects to our 2nd Lady." "They talked for ages, and even our 2nd Lady was no match for him." "He must be someone of great learning." "What did they talk about?" "T ell me." "I couldn't understand any of it." "It was all very literary stuff," "I didn't understand a word." "Sister Moon." "Brother Hua Ming." "You're here." "Pomegranate's been thinking of you." "Here's some fabric I bought for you." "Do you like it?" "No." "Look, it has a beautiful pattern." "Greetings, teacher." "I'm sorry to have been ill for a while, but I've read over your compositions." "I see great improvement." "Congratulations!" "I must let your father read them to show him how hard you've worked." "Teacher, it's enough you've read them." "There's no need to bother father just in case he gets angry." "He'll be only happy to see your progress;" "why would he be angry?" "And it'd also show I'm teaching you well." "The Grand Tutor arrives." "Thanks for coming all this way." "Welcome." "Please sit down." "Greetings, father." "Your Excellency!" "How are you?" "Why not take more rest?" "You are too kind, Sir." "I dare not leave off their studies." "It's the autumn season once again." "I expect Sir would feel inspired to drink and verse to the moon." "I'm getting too old for that." "The moon prompts the desire for reunion, in age a person feels sentimental." "It's all to do with age." "One can't help it." "I'm happy to have hired a new pageboy today." "This one." "He's quite gifted." "A pity he's fated for a life of servitude." "Teacher, why not test his literacy?" "Then you'll see if he's talented or not." "It's enough that you've already tested him, Sir." "Go on." "Have a go." "Yes sir." "Listen." "I await your instruction, Teacher." "Now that it's autumn, travelers are easily touched." "The first line of the couplet I set is:" "Hills and rivers welcome travelers' dreams." "The second line is:" "Chopping blocks and pestles sound the autumn." "What do you think, Teacher?" "Exact, literary, and quick!" "Nightingales' speech in the scented garden, sounds of laughter wafts on the breeze;" "in the study, three scholars are distraught at not glimpsing her fragrant shadow." "You're the newly-arrived Hua An?" "I am indeed." "As I am new," "I don't know the way, and took the wrong turn going to the big kitchen for water." "I'm sorry to bother you." "Don't stand on ceremony." "There's water in this small kitchen too." "Come." "Come." "Next time you can get water here." "It's all the same." "Come." "Sit down." "I'll draw water for you." "Sitting down and scrutinizing him, seeing he is so refined," "it seems such a perfect match, an unmissable match made in heaven." "Brother Hua An, sit here a while." "Sister, please draw the water quickly." "I don't want the Teacher to wait." "Sit down, and I'll draw water for you." "Very well." "Thank you, sister." "Don't forget me." "You'll have to come visit." "Certainly." "I'll come visit you." "Hua An, promise me you'll come visit." "Yes." "I'll do so." "Autumn Fragrance, I'm so fortunate to bump into you again here." "Who are you?" "Don't block my way." "Don't you recognize me, sister?" "Sister..." "Sister..." "You're here in the Grand Tutor's Mansion, surely you know the household rules?" "If you persist in blocking my way," "I'll go tell the Lady of the House, and she'll have you given 300 strokes!" "For you, sister, I'd be happy even to die." "What are a few strokes to me?" "But meeting up with you again today," "I must beseech you for a promise." "Who are you?" "Tell me your real name." "Tang Bohu, from Suzhou's Peach Blossom Dock." "If you're Tang Bohu, what are you doing here?" "Sister," "Three smiles at Huqiu locked me in love," "Three locks of love shackling my soul." "One smile when we met at the temple," "One smile when we met at the temple, a second when I was at the boat's bow, a second when I was at the boat's bow, a third smile at the town of Dongting." "a third smile at the town of Dongting." "I sold myself to the Grand Tutor's House, as three locks of love have shackled me, and only the shackler can set me free." "The first smile was unintentional, the second betrayed no love;" "the third smile was at your foolishness, an aimless youth away from his books." "You fancy yourself a lover, but I'm not a girl of easy virtue." "I'm Tang Bohu of Jiangnan, the foremost scholar of the land." "Mistake me not for a wanton man, my love for you is sincere." "If Tang Bohu of Jiangnan would rather be a servant than a scholar, it was not by my purpose or intent to shackle you with locks of love." "Sister, don't shirk responsibility." "Your three smiles came from the soul;" "with the feeling contained in those 3 smiles, how could I not have fallen in love?" "This is the crucial juncture of love." "He professes to be a foremost scholar, but the truth remains to be seen." "I'll play along for the while." "Brother Tang." "Sister." "If you have love to express to me, don't let anyone else know." "Yonder is a firewood store, we can discuss it over there." "Sister!" "Sister!" "Not so loud!" "Someone's coming." "Sister." "Sister." "Teacher, you've worked hard for years to bring my sons to this point." "I've prepared a feast to express my thanks." "It's by heaven's and Your Lordship's grace." "I've done nothing." "Thank you, My Lord." "Please." "My sons." "I've seen your recent progress." "It's all thanks to your teacher." "Not so." "Not so." "Give a toast to your teacher." "Teacher." "Teacher." "It's all down to your own hard work." "You'll be surpassing your teacher." "You have bright futures ahead." "As you've toasted your teacher," "I should give a toast to you in return." "Teacher, you're too modest." "You don't need to toast them." "You two toast the teacher again." "Yes, father." "Teacher." "Thank you, my teacher." "Hua An, Hua Xian." "Yes, My Lord." "Move a seat to the east window." "Yes sir." "Hua Ping, Hua Jie." "Yes, My Lord." "Move a seat to the west window." "Yes sir." "Brother." "Now that your writing's improved," "I want to test it for myself." "If you do well, I'll reward you." "If not, you'll have to copy out the classics." "If I find you've been cheating the teacher," "I'll deal with you as per family rules!" "Father, I haven't finished dinner yet." "You can finish it after you're done writing." "Even half a composition is acceptable." "I wish to see if your writing style matches what you submitted to teacher." "Father, may I write it tomorrow?" "Nonsense!" "Come!" "Beat him!" "Don't be angry, Your Excellency!" "You two mustn't disobey your father." "Don't worry." "You can do it." "One to the east window, one to the west." "Yes sir." "Hua An, come." "Grind the ink." "Hua An, come grind the ink." "Oh!" "Hua An, serve the drinks." "Yes, My Lord." "Teacher." "Your Excellency!" "Let them write." "Let's have a drink." "You're too kind." "Please!" "Teacher, please check my sons' writing." "Excellency!" "It seems from this the other compositions were by another hand!" "Teacher, who do you think it was?" "Obviously their wives." "I doubt it." "My daughter-in-law may be well-educated, but my household rules are strict." "They'd never dare." "That's right." "Tell me now!" "Who was it?" "Come!" "Yes, My Lord." "Beat them!" "Yes, My Lord." "Father, don't beat me." "Hua An did it." "Hua An wrote the compositions for us." "Please forgive me, My Lord." "It was the young masters' own task." "How dare you cheat His Lordship?" "My Lord." "Seeing the young masters waste away over a couple of compositions," "I made bold to do it for them." "Please punish me instead of them." "Very well." "Get up, all of you." "Thank you, My Lord." "My Lord, he admits writing the pieces." "What an insult to your sons!" "Do you believe it, on his word alone?" "You're right." "Hua An." "Here, My Lord." "The Teacher doesn't believe you did it." "Are you up to being tested?" "Indeed I am, My Lord." "Teacher, please." "Big words indeed!" "Listen carefully." "Teacher, teacher..." "Anger wells up within my breast," "I'm willing no longer to stay;" "my leave I shall take from the Grand Tutor, to spend my last years in the country." "The sun and moon rise and set, but my dream of love's yet unfulfilled;" "an entire month has passed me by, but of my love, there's still no trace." "My daily task is to accompany fools, unable am I even to be upset;" "for my love's sake must I bear it;" "when shall my love be requited?" "En garde!" "Brother, look." "You messed up the paper." "What shall we do?" "Don't worry." "Give it to me." "Hua An." "My brother... you..." "Let me add a few strokes and it will become a painting." "Wow, Hua An, you're marvelous!" "What a painter you are!" "This isn't a large pigeon." "This is a small pigeon." "How clever you are." "Can you do portraits?" "If my two young masters desire," "I can do the Two Immortals." "Yes, yes." "Wow, extraordinary!" "Two people!" "Give it to me, I'll keep it." "Brother, it's mine." "I got it first, it's mine." "What are you fighting over?" "It's a painting." "Show it to me." "Who painted it?" "What do you think of it?" "Who painted it?" "Hua An painted it." "What do you think?" "I'll show it to the Lady of the House." "Brother Hua An painted it." "The Lady will definitely like it." "Give back to me." "It's mine." "It's my paper." "Can't I show it to My Lady first?" "Can't I show it to My Lady first?" "You go have some snacks." "My Lady, look." "Hua An painted it." "It's better than even Tang Bohu's." "These Two Immortals are very well done." "Amida Buddha." "They're Han Shan and Shi De." "Mother-in-law, look again carefully." "Why does Han Shan look like my elder son, and Shi De like my younger son?" "Hua An is an ungrateful wretch." "You and father-in-law treat him so well, tasking him to accompany the Young Masters, and he caricatures them in this painting!" "The hawk means one of them is hawkish, and the pigeon means the other's brainless." "He's clearly making fun of your sons." "How dare he?" "I must punish him severely." "Yes." "Winter Fragrance." "Yes, My Lady." "Tell the slave Hua An to come here." "Yes, My Lady." "Hurry up!" "Yes, Ma'am." "Autumn Fragrance." "Yes, My Lady." "Prepare to beat him as per family rules!" "Yes, Madam." "My Lady." "Hua An is here." "Greetings, My Lady." "Hua An, your hawk and dove painting obviously pokes fun at the young masters!" "My Lady, I had no such intention." "The painting is not yet finished." "I'd meant to include a poem, but just as I wrote the 4 head words" "Winter Fragrance came while I washed hands and insisted on bringing it to you." "I couldn't stop her in time." "My Lady, it's your slave's fault for making you angry." "I see. 2nd daughter-in-law," "I knew he wouldn't be so ungrateful." "Hua An." "Hua An." "Yes." "You said the painting's complimentary." "So what poem were you going to put in?" "If it's laudatory, I'll forgive you." "If not, you'll get a good beating." "Yes, Ma'am." "Please listen:" "The hawk wins honour before the arrow, the pigeon carries the martial word;" "this soaring painting traverses the house, in praise of the two young masters." "Very good." "Mother-in-law..." "Very good, 2nd daughter-in-law." "Hua An." "Yes, My Lady." "You have some wit in turning satire to praise and avoiding punishment with sophistry." "But you must paint the bodhisattva Guanyin as recompense." "Are you willing?" "I am, My Lady." "Mother-in-law, let them arise." "All rise." "Yes, My Lady." "Thank you, My Lady." "Thank you, Second Lady." "Thank you, Second Lady." "Mother-in-law, the portrait needs a pure and chaste person to grind the ink." "Who do you think is purest?" "Autumn Fragrance." "Autumn Fragrance." "Yes, Madam." "Go grind ink in the East Hall." "No one must disturb you." "Yes, Ma'am." "Thank you, Second Lady." "Thank you, My Lady." "So ill-mannered!" "You should thank the Lady." "Together we go to the East Hall, the girl of my dreams before me;" "thanks to my cousin's help," "I can now reveal my heart to her." "Thank you, Sister Autumn Fragrance." "That day you locked me in the wood store" "till the sun set in the west," "I started hallucinating;" "you mistook me for a scoundrel." "For you I became a servant;" "how would I be insincere?" "My only wish is to marry you;" "I'd formally send a go-between." "Who are you asking to paint this?" "I'm asking you." "Is that how you address me?" "I'm not a painter by trade." "Brother Hua An, please paint it for me." "I'm not Hua An." "I'm Tang Bohu." "Why don't you call me Brother Tang?" "Are you painting or not?" "The wine's too much." "Sit here." "I'll sit wherever I want." "Sister, sister why are you so wary of me?" "You're a tiger and a wolf, the way you frighten me so;" "If you persist in pestering me," "I'll report you to Her Ladyship." "Sister, don't go." "I'm not leaving." "Just paint." "I ponder as I grind the ink:" "how many would pursue me like that?" "He claims to be Tang Bohu, but I suspect he's a fake." "His poetry and paintings are good, a scholar like him is hard to find;" "If he really is Tang Bohu, it would be a match made in heaven." "Sister, please come here." "What do you think of this painting?" "What is the meaning of this?" "I became a pageboy because of you." "How could you do this?" "Sister, don't worry." "There's a poem here," "The Moon Over the West River." "Every word and line hides my meaning." "Sister, I painted it for you." "Are you all done?" "Yes." "Ah, Brother Hua An!" "It's been days!" "I miss you so much!" "I knew you wouldn't forget me." "You've come to see me today?" "Come, come." "Let's sit inside." "Thank you, sister." "The young masters ordered me here to fetch ginseng for My Lady." "I can't stay." "Lucky for you to bump into me, or you'd have come in vain." "Today's the 15th." "My Lady's gone to prayers." "Only Autumn Fragrance is left behind." "Sister Autumn Fragrance." "How bold!" "Don't you know the household rules?" "How dare you come into the inner hall?" "Don't be angry, sister." "The young masters ordered me to get ginseng." "Ginseng?" "Her Ladyship's not back yet." "Come back later." "It's a heaven-sent opportunity!" "We can declare our love for each other." "Please give me something as a token." "Ridiculous!" "I never promised you a token!" "Your three smiles were promise enough." "Sister, please marry me." "If you want me to marry you, first you have to answer a riddle." "What riddle?" "Please tell me." "If you get it, you'll know if I'm willing." "Tell me then." "May we be lovebirds in the sky, and intertwined branches on earth;" "the hands know the will of the heart, the wish for a faithful love." "You guessed wrong." "All knowing in heaven and on earth, the gods cannot be deceived;" "the hands know that the heart is true, the truth cannot be revealed in words." "Oh, so I got it wrong?" "Mmm." "I give you another riddle." "All right." "When My Lord and Lady return, your bottom will get 300 strokes!" "Excellent!" "We think alike, you and I." "Let's elope." "Then let it be at midnight." "We'll seal our love in the rear garden." "You're a real loverboy!" "Oh!" "We'll seal our love in the Peony Pavilion." "You guessed wrong again." "Autumn Fragrance." "First Young Master." "Autumn Fragrance." "Young master, what are you doing here?" "I'll go if you'll give me a kiss." "Young Master, Her Ladyship's not back yet." "I can't possibly do that, I can't!" "If you won't, then I shan't leave." "Autumn Fragrance, don't go!" "Autumn Fragrance, give me a kiss." "First Young Master, tonight at midnight wait for me in the rear garden." "I'll give you a kiss then." "Very well." "You can go." "But give me a kiss now." "At midnight." "Please go." "Promise me you'll be there." "What shall I do?" "Why do they all take advantage of me?" "Autumn Fragrance." "Autumn Fragrance." "Second Young Master, what are you doing here?" "Young Master, My Lady's still at prayers." "She'll be back soon." "I know, Autumn Fragrance." "I'm a simple man, I don't have fancy words." "If you'll be mine," "I can abandon it all!" "Money, my wife," "I'll leave it all!" "I'll elope with you!" "Autumn Fragrance." "Autumn Fragrance." "Second Young Master, how could you?" "Everything I said is from the heart." "Autumn Fragrance." "Young Master, tonight at midnight we'll meet in the Peony Pavilion." "Very well, Autumn Fragrance." "Go now." "I'll wait for you at the Peony Pavilion." "Sister, Her Ladyship is back." "Your ladyship." "Autumn Fragrance." "Yes, My Lady." "I want you to make preparations for tonight." "I'm burning incense in the Peony Pavilion." "My Lady." "You've just offered incense." "Why do so again?" "It's cold at night in the garden." "Why not rest and do it another day?" "You forget it's the 15th today?" "The weather's neither hot nor cold." "Perfect for being in the garden." "Winter Fragrance, you help her prepare." "You two shall accompany me tonight." "Yes ma'am," "What shall I do now?" "Strange." "The First Young Master's here." "Autumn Fragrance, you fooled me again." "Careful, Your Ladyship." "Take care." "Can you see the way, ma'am?" "I can't see too clearly." "I'll go bring a lantern." "No need." "Winter Fragrance, take care of My Lady." "I'll go fetch the lantern." "All right." "Sister Autumn Fragrance." "Let me go." "Sister Autumn Fragrance, you fooled me again." "Let me go!" "Promise me, Autumn Fragrance, you'll never fool me again." "I'll only agree to marry Tang Bohu!" "Thief!" "Thief!" "Go." "You beasts!" "Your ladyship." "Kneel down, you beasts!" "Kneel down!" "Kneel down!" "You two beasts will be the death of me!" "Don't be angry, mother." "Autumn Fragrance fooled me!" "She's the cause of trouble!" "If you two hadn't tried to seduce her, why would she want to fool you?" "Daughters-in-law, you may go upstairs." "Yes ma'am." "The more I see of these unfilial sons, the angrier I get." "Keep them on a tight leash from now on." "Please don't let father-in-law know, or he'll be furious." "You're right, first daughter-in-law." "Listen, all of you." "No one is to speak of what happened." "Anyone who does will be punished." "Yes ma'am." "Autumn Fragrance." "You're at fault too, fooling your masters." "I shall have to have you beaten." "Your Ladyship, I..." "All rise." "Greetings, Grand Tutor." "I am Zhu Zhishan." "There's no need for that, Mr Zhu." "I'm retired; don't stand on ceremony." "Please take a seat." "Thank you." "Thank you." "Well." "T o what do I owe the pleasure?" "I've come to visit on two accounts." "First, Tang Bohu's been missing for months." "I can't find him anywhere." "I passed by Dongting Town today, and recalled that you're related to him." "May I ask if you know his whereabouts?" "Tang Bohu's too proud of his talents." "Although I'm related to him, our paths have never crossed." "I wonder though why he's missing?" "My 2nd daughter-in-law never mentioned it." "I'm at a loss myself." "I fear he may have had some accident." "That's why I came to pay my respects, and also to enquire about Tang Bohu." "For the latter purpose, what can you tell me?" "I heard you recently engaged a pageboy who's most gifted at poetry and painting, more so indeed than the likes of myself." "I came to see if this was indeed the case." "I came to see if this was indeed the case." "That's easily done." "Come!" "Yes sir." "Bring Hua An to pay his respects." "Yes, My Lord." "Brother Hua An." "What is your pleasure, My Lord?" "Mr Zhu here has heard of your fame." "Come pay your respects." "It's just as I expected!" "What is it, Mr Zhu?" "Your Excellency!" "Your servant's indeed a cut above the rest." "I compliment you on your choice." "I must beg my leave now." "Why the hurry to go?" "I've prepared a feast to welcome you." "Thank you so much, Excellency, but I have a boat to catch, as I must still look for Tang Bohu." "In that case, let me see you off." "There is no need, sir." "What host would not see off his guest?" "My Lord, allow me to do so for you." "That's right, your servant may do it." "I was just about to request a poem of him." "Hua An." "Yes, My Lord." "See Mr Zhu off on my behalf." "As you wish, My Lord." "Goodbye, Your Excellency!" "Goodbye." "Mr Zhu's returned!" "Mr Tang, Mr Zhu has found him." "Brother Zhu, you knew all along." "You can't hoodwink me." "The boatman told you?" "Tang, I have a cunning plan to help you trick the old man." "Thank you for your help." "How dare he?" "How dare he?" "I welcomed Zhu Zhishan courteously, but he dares to entice my pageboy!" "Does he think that in my household there's no suitable match for you?" "How did you reply to him, Hua An?" "I said, Mr Zhu had a point, but My Lord treats me extremely well." "I could not leave without a farewell." "You replied well." "Mr. Zhu said..." "Don't call him "Mister"!" "Call him by name!" "The rascal!" "Yes, My Lord." "Zhu Zhishan said I was a fool." "If I missed the chance to run away with him," "I'd never have the chance to get back home." "I'd have to be a servant all my life." "Hua An, don't fall for it." "He's just a low-ranking official." "How many maids can he afford?" "How can his household compare with mine?" "I'd thought that you might want a wife." "I'll assemble all the maids in the hall, and you may have your pick." "How's that?" "Your Lordship is too kind to me." "Hua An, from now on you'll be teaching here." "I'll have my sons address you differently." "They'll address you as "Teacher"." "You're too kind, My Lord." "Tell the butler to prepare for the wedding." "Once Hua An makes his choice, he'll marry." "Yes sir." "Fair Jade." "Lotus Fragrance." "Winter Fragrance." "Jade Ring." "Every girl is fair of face, every girl is fine of figure." "But I don't have the good fortune to spend my life with any of them." "Don't forget me, Hua An." "Sister." "You're already spoken for." "Thank you, Brother Hua An." "I wouldn't dare take another's love." "I know who you'll pick." "Sister Pomegranate." "What about me..." "My Lady, Hua An hasn't picked anyone." "Would you bear to let Autumn Fragrance go?" "No." "I can't bear to be parted with her." "Mother-in-law, ask Autumn Fragrance if she's willing or not?" "Mmm." "Autumn Fragrance, what's your desire?" "Slowly pacing her lotus steps, blushing, heart beating wildly, in shyness and glad beauty" "she takes the seal with joy and fear." "My dear." "It's a present the 2nd lady gave me." "Is it a key?" "It's the key to the rear gates." "2nd Lady, you've helped me till the end." "You really are a good cousin to me." "Mr. Tang, you're here." "The boat's ready." "Mr. Zhu, here they come." "Come, come." "Tang, the cunning plan's succeeded!" "All thanks to you, Brother Zhu." "Come aboard." "My dear." "Congratulations to you both." "Glad to be united at last, together they return home." "The fine romance of the three smiles will be passed on for all posterity."

Factors associated with age at operation for children with congenital heart disease. Previous studies have shown that children with congenital heart disease (CHD) who live in nonurban areas or who do not have private insurance are at risk for delayed referral to a pediatric cardiologist. However, the effect of these factors on the age at which cardiac surgery is performed has not been evaluated. This study is designed to evaluate the factors that influence the age at which definitive surgical repair is performed. Data on hospital discharges for 1995 and 1996 in California were obtained from the Office of Statewide Health Planning and Development database. Children <18 years who underwent surgical repair for atrial septal defect (ASD), ventricular septal defect (VSD), tetralogy of Fallot (TOF), or atrioventricular canal (AVC) were included in the study. Age at surgery was evaluated using type of CHD, gender, race, type of insurance, surgical centers, urban or rural home location, and distance between home and surgical center as independent variables. In 1995-1996, 666 children underwent ASD closure (mean age: 5.1 years; median: 4.0 years), 582 VSD closure (mean age: 2.8; median: 1.1 years), 394 TOF repair (mean age: 1.7; median:.9 years), and 177 AVC repair (mean age: 1.1; median:.6 years). Comparing median and mean age at surgery, we found: AVC<TOF<VSD<ASD (< indicates younger than). A consistent trend for all 4 types of CHD was seen indicating that for median age at operation: private insurance<managed care<Medicaid. Gender or race had no effect on age at operation, although Asians tended to be older at surgery for all 4 types of CHD. There is a significant negative correlation between the case volume of surgical centers and median age at operation for ASD (r = -.37), VSD (r = -.49), TOF (r = -.63), and AVC (r = -.17). In addition, significant positive correlation was found between degree of urbanization of home locations (measured by population density) and median age at operation for ASD (r =.50), VSD (r =.77), and TOF (r =.18). No significant correlation was found between distance to surgical center and age at operation. Many medical and nonmedical variables play important roles in determining age for definitive repair of CHD in children. Type of insurance, a recognized surrogate for access to care, may play an important role. In addition, centers with higher surgical case volume were more likely to operate at a younger age. Finally, children in urban areas tend to be older at the time of surgery for ASD, VSD, and TOF.

Biomarkers: Parkinson disease with dementia and dementia with Lewy bodies. Dementia is a common feature in Parkinson disease (PD), the time of onset determining how patients are classified. Those patients where dementia develops prior to parkinsonism or during the first year of disease are designated as having dementia with Lewy bodies (DLB). In those where dementia develops over a year after the onset of motor signs, the condition is known as Parkinson's disease with dementia (PDD). While this seems at first sight to be a definitive way to distinguish these conditions, reality is rather different. The overlap between them is considerable, and there is much uncertainty associated with patients who have both motor symptoms and early cognitive impairment. The diagnosis is still based on medical history and clinical evaluation. It is not even certain that they can be accurately distinguished at autopsy. For this reason, the data concerning these entities have been reviewed, to examine various markers employed or measured in clinical, neuropathological, neuroimaging, and biochemical investigations. The concept of PDD and DLB being separate conditions is comparatively new, and the most promising tools with which to separate them at present are cerebrospinal fluid (CSF) markers and positron emission tomography (PET) scanning that indicate increased amyloid-beta burden in DLB compared to PDD. However as yet there are no markers that unequivocally distinguish between PDD and DLB.

Movement as Investment for Health: integrated evaluation in participatory physical activity promotion among women in difficult life situations. Movement as Investment for Health (Bewegung als Investition in Gesundheit or BIG) was a multidimensional research study in participatory physical activity promotion among socially disadvantaged women in a deprived neighbourhood in Erlangen, Germany. It aimed at making full use of health-promoting effects of movement and developing integrated evaluation through approaches from different disciplines. We defined the target population through national health survey data, and determined important intervention and evaluation dimensions through meta-analyses. A co-operative planning group of women, researchers, policy-makers, and local experts made decisions on the most appropriate procedures. Integrated evaluation in participatory approaches is promising. It calls for context-specific evaluation, requires adaptation of existing approaches or even development of its own evidence base.

The American Medical Association (AMA) has officially labeled obesity as a disease in hopes that it will help change the way the medical community tackles the complex issue. As it stands, insurance companies generally exclude obesity treatment, which can limit how physicians manage obesity-related conditions like diabetes and high blood pressure. While the AMA’s decision has no legal authority, some hope that medical therapies and procedures such as the lap-band or gastric bypass surgeries will now be included in insurance coverage. Proponents of the decision contend that treatment for clinically obese patients is not as simple as eating less and exercising more. Physical mechanisms and damage to signaling pathways can make it extremely difficult for people to lose weight. Improving reimbursement for obesity drugs, surgery, and counseling may significantly impact patient outcomes. Those opposing the decision, including the AMA’s own Council on Science and Public Health, consider the measure to define obesity, the body mass index (BMI), too simplistic and flawed. They argue people with a BMI above the level defining obesity may be perfectly healthy, while others may have dangerous levels of body fat and metabolic problems. Others are concerned that the lack of specific symptoms associated with obesity classify it as more of a risk factor for other conditions than a disease in its own right. Physician’s Weekly wants to know…Will the AMA’s decision influence how you view and manage obesity among your patients? Do you think it will impact insurance...

The invention relates to interior lighting systems for passenger transport vehicles, such as aircraft, road vehicles, ships or rail cars. In particular, it relates to an LED reading light for such passenger transport vehicles. In some passenger transport vehicles, such as air planes, LED reading lights have started to become common place and have started to replace conventional halogen lights. These LED reading lights are exemplarily used as seat lights or reading lights or other interior lights in the passenger cabin. Many passenger transport vehicles have very long life cycles, at least as compared to the life cycles of LED reading lights. Also, changes to the standardisation of components for such passenger transport vehicles, such as changes to the standardized power supply system throughout the passenger cabin in an air plane, tend to be lengthy and cumbersome processes. Much of the technology used in passenger transport vehicles is frozen for long periods of time. This is both due to the keeping of the remaining components in a passenger transport vehicle when replacing certain components and due to industry standards that are constant for long times. Accordingly, it would be beneficial to provide an LED reading light having improved cost efficiency and being able to be used in passenger transport vehicles without changing their power supply systems. Further, it would be beneficial to provide a method of replacing existing LED reading lights, for example when they are used for a long time or broken, with more cost efficient LED reading lights, while keeping the wiring of the power supply systems.

I, you, me, and autism: an experimental study. The nature of autistic individuals' abnormalities in the use of personal pronouns has been a topic of considerable speculation but little systematic investigation. We tested groups of CA- and verbal MA-matched autistic and nonautistic mentally retarded children and young adults on a series of tasks that involved the comprehension and use of the personal pronouns "I," "you," and "me." All subjects were able to comprehend these pronouns within the test situations, and there were few instances of pronoun reversal. However, autistic subjects were significantly less likely to employ the pronoun "me" in a visual perspective-taking task (when instead they tended to say: 'I can see the . . .'), and lower ability subjects were more likely to use their own proper names rather than personal pronouns in certain photograph-naming tasks. There were also circumstances in which autistic subjects were less likely than controls to employ the pronoun "you" to refer to the experimenter. A high proportion of these autistic subjects were reported to have current difficulties with personal pronouns in their everyday life, and we discuss some alternative interpretations of the results.

Do-it-yourself oil changes are increasing in popularity as auto supply stores provide improved equipment to assist the car owner with expeditious removal of used oil, and service stations accept the used oil. This system relies extensively on the diligence of the consumer, particularly in bringing the used oil and oil filter to a service station or other collection point, a highly inconvenient task. Less reliance on the consumer's diligence will likely result in fewer illegally disposed of filters and simply dumped residual oil. A typical oil change involves from 4 to 6 quarts of oil and a filter which may contain as much as a quart of oil as it is removed from the vehicle. The used oil will contain in addition to the expected hydrocarbons measurable quantities of heavy metals. Disposal of the used oil or oil-containing oil filters in landfills, storm drains, or in public and private places not intended as disposal sites is potentially harmful to ground water, the atmosphere, and the flora and fauna in the area.

This disclosure relates generally to the field of boiler/furnace deslagging, and particularly, discloses a device, system and method allowing on-line, explosives-based deslagging. A variety of devices and methods are used to clean slag and similar deposits from boilers, furnaces, and similar heat exchange devices. Some of these rely on chemicals or fluids that interact with and erode deposits. Water cannons, steam cleaners, pressurized air, and similar approaches are also used. Some approaches also make use of temperature variations. And, of course, various types of explosive, creating strong shock waves to blast slag deposits off of the boiler, are also very commonly used for deslagging. The use of explosive devices for deslagging is a particularly effective method, as the large shock wave from an explosion, appropriately positioned and timed, can easily and quickly separate large quantities of slag from the boiler surfaces. But the process is costly, since the boiler must be shut down (i.e. brought off line) in order to perform this type of cleaning, and valuable production time is thereby lost. This lost time is not only the time during which the cleaning process is being performed. Also lost are several hours prior to cleaning when the boiler must be taken off line to cool down, and several hours subsequent to cleaning for the boiler to be restarted and brought into full operational capacity. Were the boiler to remain on-line during cleaning, the immense heat of the boiler would prematurely detonate any explosive placed into the boiler, before the explosive has been properly positioned for detonation, rendering the process ineffective and possibly damaging the boiler. Worse, loss of control over the precise timing of detonation would create a serious danger for personnel located near the boiler at the time of detonation. So, to date, it has been necessary to shut down any heat exchange device for which explosives-based deslagging is desired. Several U.S. patents have been issued on various uses of explosives for deslagging. U.S. Pat. Nos. 5,307,743 and 5,196,648 disclose, respectively, an apparatus and method for deslagging wherein the explosive is placed into a series of hollow, flexible tubes, and detonated in a timed sequence. The geometric configuration of the explosive placement, and the timing, are chosen to optimize the deslagging process. U.S. Pat. No. 5,211,135 discloses a plurality of loop clusters of detonating cord placed about boiler tubing panels. These are again geometrically positioned, and detonated with certain timed delays, to optimize effectiveness. U.S. Pat. No. 5,056,587 similarly discloses placement of explosive cord about the tubing panels at preselected, appropriately spaced locations, and detonation at preselected intervals, once again, to optimize the vibratory pattern of the tubing for slag separation. Each of these patents discloses certain geometric configurations for placement of the explosive, as well as timed, sequential detonation, so as to enhance the deslagging process. But in all of these disclosures, the essential problem remains. If the boiler were to remain on-line during deslagging, the heat of the boiler would cause the explosive to prematurely detonate before it is properly placed, and this uncontrolled explosion will not be effective, may damage the boiler, and could cause serious injury to personnel. U.S. Pat. No. 2,840,365 appears to disclose a method for introducing a tube into “a hot space such as an oven or a slag pocket for an oven” prior to the formation of deposits in the hot space; continuously feeding a coolant through the tube during the formation of deposits in the hot space, and, when it is time to break the deposits, inserting an explosive into the tube after the formation of the deposits while the tube is still somewhat cooled, and detonating the explosive before it has a chance to heat up and undesirably self-detonate. (See, e.g., col. 1, lines 44-51, and claim 1) There are a number of problems with the invention disclosed by this patent. First, the hot space according to this patent must be thoroughly prepared and preconfigured, in advance, for the application of this method, and the tubes that contain the coolant and later the explosive, as well as the coolant feeding and discharge system, must be in place on a more or less permanent basis. The tubes are “inserted before the deposits begin to form or before they are formed sufficiently to cover the points where one wishes to insert the tubes” and are “cooled by the passage of a cooling fluid . . . therethrough during operation.” (col. 2, lines 26-29 and col. 1, lines 44-51) It is necessary “to provide sealable holes in several bricks for allowing the tube . . . to be inserted, or . . . to remove the bricks during operation of the furnace so that a hole is formed through which the tube may be inserted.” (col. 2, lines 32-36) The tubes are supported “at the back end of the pocket upon supports made for the purpose, e.g., by a stepped shape of the back of the wall . . . [or] at the front end or in front of and in the wall . . . [or by having] at least the higher tubes . . . rest immediately upon the deposits already formed.” (col. 2, lines 49-55) A complicated series of hoses and ducts are attached for “feeding cooling water . . . and discharging said cooling water.” (col. 3, lines 1-10, and FIG. 2 generally) And, the tubes must be cooled whenever the hot space is in operation to prevent the tubes from burning and the water from boiling. (see, e.g., col. 3 lines 14-16 and col. 1, lines 44-51) In sum, this invention cannot simply be brought onto the site of a hot space after deposits have formed and then used at will to detonate the deposits while the hot space is still hot. Rather, the tubes must be in place and continuously cooled essentially throughout the entire operation of the hot space and the accumulation of deposits. And, significant accommodations and preparation such as tube openings and supports, the tubes themselves, and coolant supply and drainage infrastructure, must be permanently established for the associated hot space. Second, the method disclosed by this patent is dangerous, and must be performed quickly to avoid danger. When the time arrives to break the slag deposits, “the pipes . . . are drained,” various cocks, hoses, bolts and an inner pipe are loosened and removed, and “explosive charges are now inserted [into the pipe] . . . immediately after termination of the cooling so that no danger of self-detonation exists, because the explosive charges cannot become too hot before being exploded intentionally.” (col. 3, lines 17-28) Then, the “tubes are exploded immediately after stopping the cooling at the end of the operation of the furnace . . . ” (col. 1, lines 49-51) Not only is the process of draining the pipe and readying it to receive the explosive fairly cumbersome, it must also be done in a hurry to avoid the danger of premature explosion. As soon as the coolant flow is ceased, time is of the essence, since the tubes will begin to heat up, and the explosives must be placed into the tubes and purposefully detonated quickly, before the heating of the tube become so great that the explosive accidentally self-detonates. There is nothing in this patent that discloses or suggests how to ensure that the explosive will not self-detonate, so that the process does not have to be unnecessarily hurried to avoid premature detonation. Third, the pre-placement of the tubes as discussed above constrains the placement of the explosive when the time for detonation arrives. The explosives must be placed into the tubes in their preexisting location. There is no way to simply approach the hot space after the slag accumulation, freely choose any desired location within the hot space for detonation, move an explosive to that location in an unhurried manner, and then freely and safely detonate the explosive at will. Fourth, it may be inferred from the description that there is at least some period of time during which the hot space must be taken out of operation. Certainly, operation must cease long enough for the site to be prepared and fitted to properly utilize the invention as described earlier. Since one object of the invention is to “prevent the oven . . . to be taken out of operation for too long a time,” (col. 1, lines 39-41, emphasis added), and, since the “tubes are exploded immediately after stopping the cooling at the end of the operation of the furnace or the like” (col. 1, lines 49-51, emphasis added), it appears from this description that the hot space is in fact shut down for at least some time prior to detonation, and that the crux of the invention is to hasten the cooling of the slag body after shutdown so that detonation can proceed more quickly without waiting for the slag body to cool down naturally (see col. 1, lines 33-36), rather than to allow detonation to occur while the hot space is in full operation without any shutdown at all. Finally, because of all the site preparation that is needed prior to using this invention, and due to the configuration shown and described for placing the tubes, this invention does not appear to be usable across the board with any form of hot space device, but only with a limited type of hot space device that can be readily preconfigured to support the disclosed horizontal tubing structure as disclosed. Luxemburg patent no. 41,977 has similar problems to U.S. Pat. No. 2,840,365, particularly: insofar as this patent also requires a significant amount of site preparation and preconfiguration before the invention disclosed thereby can be used; insofar as one cannot simply approach the hot space after the slag accumulation, freely choose any desired location within the hot space for detonation, move an explosive to that location in an unhurried manner, and then freely and safely detonate the explosive at will; and insofar as the types of hot space devices to which this patent applies also appear to be limited. According to the invention disclosed by this patent, a “blasting hole” must be created within the subject hot space before the invention can be used. (translation of page 2, second full paragraph) Such holes are “drilled at the time of need or made prior to the formation of the solid mass.” (translation of paragraph beginning on page 1 and ending on page 2) Since the device for implementing the process of the invention “includes at least a tube that permits feeding the cooling fluid into the bottom of the blasting hole” (translation of page 2, fourth full paragraph) and, in one form of implementation, “a retaining plate . . . positioned at the bottom of the blast hole (translation of paragraph beginning on page 2 and ending on page 3), and since it is a key feature of the invention that the blast hole is filled with coolant prior to and during the insertion of the explosive, it may be inferred from this description that the blast hole is substantially vertical in it orientation, or at least has a significant enough vertical component to enable water to effectively accumulate and pool within the blast hole. Because the subject hot space must be preconfigured with a blast hole or holes (with implicitly at least a substantial vertical component) before this invention can be used, it is again not possible to simply approach an unprepared hot space at will after deposits have accumulated, and detonate at will. Since the coolant and the explosive must be contained within the blast holes, it is not possible to freely move and position the explosive wherever desired within the hot space. The explosives can only be positioned and detonated within the blast holes pre-drilled for that purpose. Due to the at least partially vertical orientation of the blast holes, the angle of approach for introducing the coolant and the explosive is necessarily constrained. Also, while it is not clear from the disclosure how the blast holes are initially drilled, it appears that at least some amount of boiler shutdown and/or disruption would be required to introduce these blast holes. Finally, in both of these cited patents, the components which hold the coolant (the tubes for U.S. Pat. No. 2,840,365 and the blast holes for LU 41,977) reside within the hot space, and are already very hot when the time arrives to deslag. The object of both of these patents, is to cool these components down before the explosive is introduced. U.S. Pat. No. 2,840,365 achieves this by virtue of the fact that the tubes are continuously cooled throughout the operation of the hot space, which, again, is very disruptive and requires significant preparation of and modification to the hot space. And LU 41,977 clearly states that “[a]ccording to all its forms of implementation, the device is put in place without a charge for the purpose of cooling the blast hole for a few hours with the injection fluid. (translation of page 4, last full paragraph, emphasis added) It would be desirable to avoid this cool down period altogether and therefor save time in the deslagging process, and to simply introduce a cooled explosive into a hot space at will without any need to alter or preconfigure the boiler, and to then detonate the cooled explosive at will once it has been properly placed in whatever detonation location is desired. And most certainly, the application of LU 41,977 is limited only to hot spaces into which it is feasible to introduce a blast hole, which appears to eliminate many types of heat-exchange device into which it is not feasible to introduce a blast hole. It would be desirable if a device, system and method could be devised which would allow explosives to safely and controllably be used for deslagging, on-line, without any need to shut down the boiler during the deslagging process. By enabling a boiler or similar heat-exchange device to remain on-line for explosives-based deslagging, valuable operations time for fuel-burning facilities could then be recovered. It is therefore desired to provide a device, system and method whereby explosives may be used to clean a boiler, furnace, scrubber, or any other heat exchange device, fuel burning, or incinerating device, without requiring that device to be shut down, thereby enabling that device to remain in full operation during deslagging. It is desired to enable valuable operations time to be recovered, by virtue of eliminating the need for shutdown of the device or facility to be cleaned. It is desired to enhance personnel safety and facility integrity, by enabling this on-line explosives-based cleaning to occur in a safe and controlled manner.

"'Today in Moscow, President Bush and President Putin met 'for their economic summit." "'$20 billion of aid to the Russian Federation 'has been granted by the International Monetary Fund." "'Our correspondent, Geoff Meade, is in Moscow." "'Geoff, $20 billion." "A huge amount of money?" "'" "'Kay, this is a massive vote of confidence in the Russian Federation." "'And it's very much down to pressure from Bush that this aid has been given.'" "Patience." "(Shouts in Russian)" "Ah!" "You are a clerk at the Ministry Financo." "You have a password to an account." "I can't access it unless you enter the password." "Please do so now." "What's the matter?" "It's only American money." "Yes." "Thank you." "(Gunshot)" "(All) Na zdorovye." "(Distant siren)" "Do we really have to involve them?" "Can't Ml6 do the job?" "They want to keep a safe distance and the last thing we want is the Fraud Squad." "Dear God, no!" "So we're stuck with these people." "Ah, Harry." "Come in." "Sir John." "This is Tom Quinn." "Sir John Barry, Governor of the Bank of England." " Pleased to meet you." " Tom." "This is Sir Richard Bowman, head of the bank, Bowman and Company." " Pleased to meet you." " How are you, Dicky?" "Oh, not quite in the pink, but well." " Dicky and I go back a very long way." " Right." "So, shall we?" "Actually, someone is joining us." "Here she is." "Running a little late." "Hope no one's inconvenienced." "Please, sit down, everyone." "This is Amanda Roke from the Chancellor of the Exchequer's office." "Ms Roke, this is Harry Pearce and Tom Quinn from Ml5." "Pleased to meet you, Ms Roke." "You're a Treasury civil servant?" "I'm the Chancellor's political counsel." "Ah." "Perhaps Sir Richard should..." "Last night, one of our employees stole $1 billion from us." "This is our thief" " John Lightwood." "A young man I would've trusted with my life." "The Chancellor is deeply concerned about this matter." "Bowman and Co is more than an old family bank." "It is a British institution." "A scandal like this could send it to the wall, trigger a stock exchange crash, even lead to a major economic depression." "We cannot allow that to happen." "That is why we suggested Ml5 be called in to find John Lightwood and recover the money he stole." "Surely this is a job for Scotland Yard?" "There's a sensitivity here." "Police would mean court cases" " and leaks to the press." " What sensitivity?" "Look, all you have to do is do what you're told." " I beg your pardon?" " It's all right, Tom." "The stock exchange may tremble but banks have failed before and Ml5 hasn't been called in." "What's so special about this case?" "Very well." "Bowman and Company handle certain government accounts." " Ah." " So you're the government's dirty bank?" "I don't think this is helpful." "This is very adventurous of you, Dicky." "Thank you, Harry." "As far as Ml5 is concerned, this operation is strictly on a need-to-know basis." "All you have to do is find John Lightwood and the money." "This is his file." "Right." "Well, you'd better get on with playing at policeman." " You will liaise with my office." " Absolutely." "(Siren)" "What'll they want next?" "Officers as traffic wardens?" "It stinks." "I agree." "I've known Dicky for years." "I've never seen him so worried." "We could put someone in the bank undercover." " Good idea." " Really?" "Why not?" "We are spies." "We're doing all we can to find John Lightwood." "Mobile phone usage, credit cards, the works." "Probably in Barbados now." "I had Special Branch turn over his flat and the bank have identified this man as Tim Prachett." "He's also a trader at Bowman's." "Seems like those two were best friends." "Do I get the impression you all hate doing this?" "Well, I'm with you." "Enough playing at PC Plods." "We're putting an officer into this bank, undercover." "No one pulls the wool over our eyes and no one will be told, certainly not Sir Richard." "So who's going in?" "Me?" "Undercover in a bank?" "You've a history of swindling credit cards." "I thought you'd be peffect." "Oh, yeah." "Thanks." "They want to replace Lightwood." "We'll make sure you get the job." "Malcolm will give you a legend and a great CV and Ruth'll teach you share trading." " Don't worry, it's all about cheating people." " Oh, right." "Zoe, I want you in there as well." "Go through records, files." "We want records of Lightwood transferring this money." "I want to know what they're not telling us about this bank." "We can see who can make the most money." "You'll make zilch." "You'll be a cleaner." " Buy half a yard at 75." " OK, done." "Zurich silver." "Selling half a yard at 82." " Too high, Danny." " Look at Singapore." "Cripes!" "OK, done." " Ruth, what just happened?" " Danny just made 50 grand or he would've if we'd been really trading." "How do you know all about this stuff?" "I was in love with a big swinging dick." "That's slang for a trader." "How's Danny measuring up?" " Oh, he's a huge talent." " I was afraid of that." "So what news from our cousins over the water?" "Washington CIA are hyperventilating about money." "$20 billion of aid has gone missing in Moscow." "American money." "20...?" "It's goodwill to Russia, to get them in step on the Middle East." "The money could come here." "If you hear anything at all, you'll tell us?" "You'd gain much love from the heart of America." "How could I refuse?" "Tim, this is Joshua lkoli." " Hi." " Hi." "Joshua will do John Lightwood's accounts." "He's very hot stuff." "Blazing references." " Have to watch ourselves, then, won't we?" " Indeed." "Tim will help you if you're not familiar with the systems." "All right, Tim?" "Yeah." "I look forward to your accounts at the end of the day then, Joshua." " The disgraced man's shoes." " I don't get you." "They say Johnny Lightwood stole money." "Success or theft?" "It's a thin line in this game." " You could say that." " Did you know John Lightwood well?" "Don't be crass." "None of us know each other that well round here." "Why the hell should we?" "Jazzer, Josh at Bowman's." "Yeah, great." "Socking it to the natives over here." "GCHQ says the German government is manipulating the cost of German steel." "'They want the price up five points.'" "No trade." " First-day nerves?" " Never piss on your own shoes." "True, true." "This is Joshua lkoli, new at Bowman's." "Yeah, hi." "Düsseldoff Steel - buy a hundred at 67." "Thanks." "Did you just squeeze the price on those options and sell them on?" "Yep." "Christ, you just made 250 grand, minimum." "Yep." "This is Joshua lkoli, new at Bowman's." "Ah, Zoe." "You have delivered me shredding." "Delicious." " (Zoe) 'How long will it take?" "'" " An artist cannot be hurried." " Oh, yes, he can, Malcolm." " (Beeps)" "(Police radio, indistinct)" " Tom." " Hi." "It's definitely your man." "He's in a right mess." "(Camera clicks)" "They crucified him." "Looks like." "I want Special Branch on to all the media." "No news, no press, absolutely none." "OK." "Someone's sending a warning." ""Mess with us, we'll crucify you."" "Look, I've got an order to buy at 52 and 100 million." "Can you improve on that?" "OK." "No sale, no trade." " I'm Maxi Baxter." " Josh lkoli." " Nigerian?" " My dad." "I was born in Peckham." " That'll be good." " Go for it." " Yeah!" "OK!" " Yes!" "Welcome to the animal room, Peckham boy." "Singapore." "Hi, Lei Fing, it's Maxi." "I want 50 Hang Seng at market price." "(Man) Deal!" "...work for you." "I really can." " 48, 49." " Come on, come on." " Yep." " But that's what I said to you this morning." "(Bell rings, low cheering)" "Bitch day!" "Bitch market!" "I wrenched my testicles just to keep even." "How about you?" "Up 1.5 mil." "(Applause, whooping)" "Animal room trader of the day." " A tradition." " And drinkies are on you." " Whoo!" " Oh, great!" " Great." "A greasy evening?" " Hm." "All right." "Little girls'." "She is a bad woman." "You want to find out how bad, sleep with her." "Johnny Lightwood did." "Noted." "What's the rest of the squeeze like around here?" "I'm off." "Girly club." " They lick you." " I'll have some of that." "Good man." "(Liberty X:" "Just A Little)" "Get hot just a little" "Meet me in the middle" "Let go just a little bit more" "Just a little bit" "Give me just a little bit more" "Just a little" "Oh baby won't you just" "Work it a little" "Get hot just a little" "Meet me in the middle" "Let go just a little bit more" "Just a little bit" "Give me just a little bit more" "Just a little bit more" "Work it a little" "Get hot just a little" "Let go just a little bit more" "Just a little bit" "Give me just a little bit more" "(Laughing)" "To pleasure." "Yeah." "I mean, abusing your mind and your body." "It's sort of an art form." "John Lightwood good at that, was he?" "Lightwood?" "Ooh!" " An artiste of the good times." " (Laughing)" "He couldn't say no to nothing." "He'd a big thing going." "What thing?" "Don't know if I ought to say." "Try me." "Johnny Lightwood was helping dirty money through the bank." " Tasty." " Very." "Money laundering these days." "If you've got the bottle, why not?" "You know?" "I mean, this is the mother of bear markets, right?" "But everything's in pieces." "A butteffly flutters in Tokyo, millions are wiped off the London, New York exchanges." "In times like these, if you can't make money the right side of the line, go over it." "And John was well over the line?" " All the way to Lugano." " Lugano, Switzerland?" "Is that where the money was going?" " To the Banco Co-operativo." " (Belches)" "Whose name was the account in?" "No idea." " You're not as pissed as me." " (Laughs)" "Come on!" " I wouldn't say that." " You love it." " Come on!" " Ooh!" "Sorry about the early morning debrief, Danny!" "Needs must." "Things are becoming murderous." "John Lightwood was tortured to death." "We must know why." "But, Danny, you and Zoe watch your backs." "Hear me?" " Sure." " Right." " Money laundering." "Do we understand it?" " You wash money clean." " See laundrettes." " Right." "It's not laundrettes, it's banks." "You move the money from one bank to another so fast, no one knows where it came from." " And Bowman's is?" " One bank on the way." "It can be there then not there in a second." "Don't think of cash, coins and notes." "It's..." "It's like a cloud." "It can be blown around the world, split into little clouds and can gather in a big storm in one place." "It's a very beautiful thing, money." "Do we have anything on this bank in Lugano?" "It's a Swiss bank." "God Almighty himself wouldn't get a statement and its computers are firewalled." " You can't even get a staff list." " Do they have a London office?" "Yes, they have a suite permanently booked at the Royal Paramount Hotel, Mayfair." " A hotel suite?" " To entertain clients discreetly." "Maxi Baxter." "I think she slept with Lightwood." "Can we get everything on her?" "Yes." "Ruth, you look into this woman." "Let's put an obbo on the hotel." "Are the security circuits in the rooms turned off?" "Don't worry, I checked." "Here's a copy of the Official Secrets Act." "Sign it for your own peace of mind." "My guests must not know." "They won't." "No one sees us, we go through walls." "Just pop through the wall, get us a cup of tea would you, Mal?" "Sorry." "Got a bit carried away there." "Right." "Let's bug this place and go." "Tom, it was Russian." " What?" " The way they crucified him." "Look." "Here's a 16th century Russian icon." "See?" "Arms straight, feet not crossed." " A Russian did this." " Russia." "It's right in the tradition of the Russian mafia." "This was your father's room, wasn't it?" "I should never have got involved with you." "I approached you." "Remember?" "You were horrified but then you said yes." "For a handsome commission." "This boy, Lightwood." " You had no idea what he was doing?" " I swear to you, no." "Greed must have overcome him." "But in the name of God, why leave him on Hampstead Heath like that?" "It was a warning... to you, you genitally-shrivelled, English pant-pisser." "That is so much better in Russian." "If only you spoke my language." " You're insane." " No." "Just free to do what I want." "The huge sums of money make anything possible." "Listen, English banker." "The transfer of $1 billion was a trial." "Now we have to take the risk of transferring the rest of the money out of Moscow." " $19 billion." " Oh, God!" "The CIA, the Russian Federation security services, are looking high and low for that money." "It must go in the next 48 hours." "Nothing will go wrong this time." "When the money comes into your bank, you will personally make sure it gets to Switzerland." "Understand?" "What is that?" "It's beautiful." "I had no idea your father owned an icon by Dionysius." "15th century." "It's incredibly rare." "Do you know what Dostoevsky said?" ""Beauty will redeem the world."" "Please, take it as a gift." "Why, thank you, Dicky." "I'll see myself out." "(Phone)" " (Beeps)" " Speak." "Shvitkoy wants to launder the rest of the money." " When does he want to do it?" " In 48 hours' time." " Well, terrific." " I don't see anything terrific about it." " This time, it'll work." " It's too dangerous." "Same as before." "Who'll handle the money this time?" "I don't know." "I can't think." " All right." "I will." " No." "You must be deniable in this." "I am very unhappy." "I want to talk to the Chancellor." "This is too sensitive for the Chancellor." " But if it goes wrong again..." " Sir Richard!" "We are all aware of the risk you are taking for the government." "I'm not taking it for the government." "I'm taking it for the country." "Yes, of course." "Just find someone to do it." "Sir Richard?" "So, what do we have?" "An amazing thing." "Richard Bowman opened an account for John Lightwood with a balance of £500,000, the day the $1 billion went missing." " A bonus?" " Nope." "They're paid at the end of the year." "This was done by Sir Richard with a copy sent to Lightwood and someone destroyed any record of it." "Or thought they had." "Until our Leonardo of the dustbins got hold of it." "Oh." "Thank you, Harry." "So what does this mean?" "John Lightwood was paid to steal from the bank?" "We need to know more." "Tell Danny to get friendly with the Maxi girl." "As friendly as it takes." "(Maxi) A carrot and coriander cocktail." "They say back in the '80s, young city bloods like us drank two bottles of champagne for lunch." "Heroic days." "But where are all the young bloods now?" "In alkie clinics." "Though some get away with it still." "Like John Lightwood." "Really?" "And what is it you think he got away with?" "The jungle drums say he nicked a billion dollars." "Now there's a true modern hero." "He was a friend of yours, wasn't he?" "Maybe." "What are you saying?" "Do you want to try what he did?" "Well, you know this male thing we have - recklessness." "I don't think that's just a male thing." "Tim said you were a bad woman." "Do you think he's right?" "He said there's a way I could find out." "Are you going to try it?" "Would I be allowed?" "That depends on the strength of your market penetration." "Of course." "(Harry) Does Downing Street want to know what's going on?" "It does not want you accusing Sir Richard of laundering Russian mafia money!" " Close the door." " You exceeded your remit." " Remit?" " You put a mole in the bank." "We must know what's been going on at Bowman's." "You're inteffering with matters that aren't your concern." " You are to withdraw your officer." " Are you giving us orders?" " Absolutely!" " And who are you to do that?" "Are you from the Joint Intelligence Committee?" "No." "Are you a member of government?" "No." "Did someone elect you?" "No." "Are you a real civil servant?" "No." "So what are you?" "Take this seriously, gentlemen." "Very seriously." "How come our gremlin in Downing Street knows Danny's undercover?" "If there's a leak here, we must plug it now." "Colin." "I'm gonna have to trust you." "I just have to take that leap in the dark." "What do you mean?" "Someone has been passing on the details of the bank operation." "I want you to monitor all the computers on the grid." "You want me to snitch?" "I don't want to do that, Tom." "This job asks difficult things of us sometimes, Colin." "(Typing)" " I suppose you have evidence?" " Computer traffic from your station, yes." " I coded it good." " Colin uncoded it good." "You betrayed us." "Ml5 is a government department." "I only told Downing Street what you were doing." "The government can't betray itself to itself." "Don't be naive, Ruth." "You know exactly what's going on here." "GCHQ planted you on us." "Tom, I so much wanted to join Ml5." "To be a real spy." "They said I could have the transfer if... very occasionally, I reported what you were doing." "This is the first time I've done it." "Reported directly to Amanda Roke?" "Well, now you're a classic double agent." "How does real spying feel?" "The horrible thing is, it's rather exciting." "Ruth, I've got two officers in the field at high risk." "Do you want to get Danny or Zoe crucified on Hampstead Heath?" "Don't." "I'll have to tell Harry." "I'm so bloody good at this job." "You know I am." "Well... that's that, then." "Of course, double agents can be turned." "Oh, Tom." "You're on probation." "Thank you." "No, it's not a thing I should have done." "As a banker, I am ashamed of myself." " Why?" "What have you done?" " I've booked a hotel room." "Well, er..." "You don't mind?" "No, I love it." " Is it...?" " Around the corner, Park Lane." "Oh, you are not thinking "greasy Italian man"?" "Oh, yes, I am." "Shall we...?" "It's the Royal Paramount." " Mm, posh." " Of course." "But if you don't like..." " Oh, no, no, no, no." "I like." " Ah." "Oh, no." " (Zoe) 'This feels so decadent.' - 'I'm glad you like it.'" "'Oh, and there is this.'" "No, no." "How dare you put an obbo team on me." " We rigged that room to see what we'd get." " I hope you all had a good gawp." "Oh, Zoe." "Who was on obbo duty?" "Colin." " You didn't sign in you were seeing him." " I'm not the first to do that." "He took you to rooms used by a Swiss bank, the same bank the laundered money was destined for." "Oh, please God, no." "You know what's going to have to happen next?" "What?" "Are you going to tell me I can carry on sleeping with him if I inform on him?" "I'm sorry, Zoe, I have to tell you." "He's married." " No, he's not." " Her name's Maria." "She's the daughter of the Italian finance minister, Antonio Gustino." "Your man married very advantageously." "For God's sake, Zoe, you didn't even look him up." "Mm?" "I, erm," "I just wanted a little bit of space, just for my own life, you know?" "I will get Colin to lose that section of the tape and I will shut him up but we need to know if this man is involved." "Yeah." "OK?" "Yeah." "Tom, something wondefful." "Death certificate." "Maxime Anne Baxter." "Died in Victoria Gardens, Farnham, Surrey, 31 March 1979, aged 3 months." "Birth certificate." "Maxime Anne Baxter." "Born Victoria Gardens, Farnham, Surrey, 31 December 1978." "This birth certificate used to get a minor's British passport in 1990." "My God." "What about, er, schools on her CV from the bank?" "Enrolled at Salehill Boarding School, aged 13." "Good place for the oddball girl." "Before that, she was meant to have gone to, Farnham Park, has no record of her." "And there are no records at all - doctors, anything - before 1990." "She suddenly appeared in London with a complete legend?" "It's a puzzle, isn't it?" " Ruth, this is great work." " Tom, I'm so glad you think so." "Come with me." " A wild guess." " Try me." "Daughter of a powefful man." "Wants her safe in England, has the clout to get her a new identity in 1990," " when the Soviet Union's collapsing." " Ex-KGB, turned businessman." "I'm beginning to see him in the shadows." "Aren't you?" "So?" "Can we set up a trap for this girl?" "All right." "But the budget won't run to the Docklands shag-pad of Danny's dreams." "His flat will have to do." "Get a team to erase Danny's identity and tart it up." "So, er, we walk round to the hotel?" "My lunch time's almost over, actually." "Better get back." "But lunch time was your idea." "Emma, have I offended you?" "I don't want to see you any more." "What?" "It's because of work." "Work?" "You're a banker and, er, we're doing some work with the bank." "So?" "So there's a conflict of interest." "Dear God, you're talking like some middle-aged bureaucrat." "I can't have my work compromised." "I'm very ambitious." "I love my work." "It's, er..." "It's just this thing I've got." "Hey, no, don't do this." "Mr Carlo Franceschini." " Who are you?" " We work for a government department." "Why should I believe you?" "You could be common muggers." "Your father, Alberto, was born in Milan." "Your mother Margherita, maiden name Pollini, is Italian Swiss." "What is this about?" "$1 billion was stolen from a British bank." "The money was placed in an account in the bank you work for." " We want the name of its user." " Hm." "How about the secret name of God as well?" "The men who stole this money are major criminals." "They kill." "Look, for a bank, money is morally neutral." "Mr Franceschini, think very carefully about the situation you're in here." "The situation is, I am sitting as a free man in a pub in a free country." "Do you wish your wife to receive copies in the post?" "Or we could e-mail them to her and to her father." "You realise, for the Swiss, a banker's confidence is as binding as that of a doctor or a priest?" "The account is held in the name of Victor Shvitkoy." "Why did you allow us to come into this without knowing that one of the most powefful psychopaths in the Russian mafia was involved?" "Did you know he has an agent working in your bank?" "Oh, no." "Not Maxime Baxter." "She's one of our best." "Birth certificates, passports - everything's false." "We believe she's Victor Shvitkoy's daughter." "Dear God." "(Tom) I have two officers in the field." "One of them is going to meet this woman in two hours' time." "So we must know, why is Bowman's Bank involved with this money?" "Governor." "Explain." "I have Downing Street's authorisation?" "When the $20 billion of aid went missing in Moscow," "Victor Shvitkoy approached Sir Richard." "Would he be interested in handling a large sum of money very quickly?" "When I reported Shvitkoy's approach to Ml6, they asked me to do what Shvitkoy wanted." "Sting him." " Yes." " Steal the money from him?" "I instructed John Lightwood to move the $1 billion into Shvitkoy's Swiss account." "That was a trial run." "Unfortunately, Mr Lightwood stole it." "And Shvitkoy found him." " Yes." " What about the other 19 billion?" "Shvitkoy is still going to try to launder it." "He believes I am his creature." "He thinks I can be used." "You realise governmental proximity cannot be acknowledged?" "The Treasury can't be seen near laundered money?" "Yes." "This will be yellow flagged "top secret" all the way, have no fear." "An incredibly brave and dangerous game, Dicky." "Nature intended me to sit behind a desk balancing books, not go double-crossing Russian gangsters." "All the more credit to you." "(Phone)" "Excuse me." "I must... concentrate." "The idea was... and is..." " to steal the money back." " For the Americans?" "(Russian man) 'Sir Richard." "'Dicky." "'I like calling you by your familiar name." "'We are close to doing a famous thing, a famous theft." "'You have no choice but to move the money." " 'Do you understand?" "'" " Yes." "I understand." "Is there something you're still not telling us?" " I can assure you..." " Governor!" " (Harry) Dicky." " (Moaning)" " (Governor) Richard." "...EC1." "(Struggling) Shvitkoy." "He's transferred the rest of the money" " from Moscow." " He's had a stroke." "Account number... 5, 9," "9, 8, 7," "4, 9, 5." "The money will only be at the bank for a few minutes." "Your man must divert it at once." "I know exactly what my man must do and at what risk." "(Phone)" "Yep?" " Right." " You look like a man getting a tip." "Something like that." "Give me the numbers." "5, 9, 9, 8, 7, 4, 9, 5." " Want me to repeat that?" " Don't bother." " What did you do just then?" " How do you mean?" "Were you transferring something in the main foreign accounts?" "No, just taking a look." "Taking five." " There's a problem." " (Russian man) 'Speak.'" " Has the money reached Lugano?" " 'I've not been advised.'" "God, no." "It's happened again." "'All right." "Keep calm." "Calm!" "'Listen to me." "Do you know who is responsible?" "'" "I think so." "Yes." "'Right, stay with him, do anything he wants to do." "'But get him to tell you where the money is." "(Fervently) 'Maxime, anything." "'Do what I say!" "'" " I have just nicked $19 billion." " Danny!" " What an amazing experience." " Danny, can you concentrate?" " What?" " Are you with me?" "Your lady friend is the daughter of a Russian hood called Victor Shvitkoy." "He killed John Lightwood." "What are Tom's orders?" "Our lovely flat now has the trappings of a luxury banker's pad." "Can't wait." "Whatever you do, stay with Maxi." "Do whatever you have to to find out where her father is and..." "And be careful, Danny." "Hope there's good booze in the fridge." "I'll do it tonight." " Ready?" " Dark side of the moon?" "Ooh, yes, please." " They're leaving." " Good, Zoe." "Go after them." " They're on their way." "Black London cab." " (Colin) I've got a signal." " Are we ready with the flat?" " Surveillance systems are operational." "Colin, when the word "yes" will do, use it, right?" " Yes." " Let's try and stay on top of this, shall we?" "Come on, Danny." "Thought you'd be more upscale than this." "It does me." "I'm never here." "Drinkies?" "Please." "Ah, shampoo." "Here we go." "What are we celebrating?" "I, er, don't know if I should tell you." "I've got some unbelievably hot info." "What?" "'You wouldn't believe it.'" " She's..." " We're OK." "We're OK." "Try me." "Good old Sir Richard Bowman's family bank is laundering dirty money." "Really?" "And, er, I've nicked it." " You've what?" " It was going from Moscow to Lugano through Bowman's, so I pushed it into a little account of mine." "Well, a very big account now." " How much?" " 19 billion smacks." " This is very risky." " He's trying to hook her." "'Lsn't that what John Lightwood did?" "'" "Lightwood?" "Disappeared, hasn't he?" "I don't know if you're a brilliant thief or a fool or what." "Brilliant thief and in a celebrating mood." "Where's the bedroom?" "(Maxi laughs) 'I do love a corny man.'" "I mean, I'm not actually stealing the money." "No." "I want to return it to its rightful owner." "For a little commission?" "Just two mil." "I mean, I'm not greedy." "No." "Little puritan, aren't you?" "Trouble is, I have to find the rightful owner." "Yes, you do, don't you?" "Can you help me there?" "What makes you ask that?" "Instinct." "What happened to that champagne?" "I'll be right back." " She's..." " The cleaners didn't do their job." "Hold." "Everyone, hold." " I'm going." " What?" "I've left my inhaler back home." "Sorry, I'll have to go." " Shall we lift her?" " Wait." " I'll come with you." " Will you, now?" " What do we do?" " We let them leave." " Danny will be at serious risk." " Yes." "Thank you." "(Distant car alarm)" "Done the place up, have you?" "It's a real bolt hole." "I got it for a song." "Great." "Don't stand in the cold." "Come in." "Ow!" "Bastards!" "So," "Mr Daniel Hunter." "My daughter tells me she thinks you are very beautiful." "I don't think so." "No?" "Well, if I put your eyes out, you wouldn't have to look at your face in the mirror." " Look, I'll do you a deal." " Excellent." "This is the deal I want." "Listen." "You have some money of mine in an account at a bank called Bowman's and Company." "Kindly tell me the codes, the number of the account, so I can enter the details into this computer and transfer the money." "Huh?" "Listen." "My colleague is holding a knitting needle." "And he will now put it straight through the cornea of your eye, into the optic nerve." "I found this in his clothes." " It's toothpick." " (Maxi) That's what I thought." "You see, Victor, tracker equipment's come on a lot since you were in the KGB." "(Slow, heavy breathing)" "(Officer talks, indistinct)" "(Sighs)" "The Chancellor of the Exchequer, too, has asked me to thank you." "It was a highly satisfactory outcome." "Many thanks." "I do hope your hearing's better." "Sorry, what?" "(Laughs) Sorry." "Well, I shall leave you to your internal debrief." "Certainly." "After the excitement, the paperwork." "Written statements, then Tom and I will do the personal debriefings." "Excuse me." " What about the money?" " What?" "The $19 billion." "All of, what, £13 billion?" "What happens to it?" "The right thing." "(Christine) Funny, you were talking about money." "(Tom) No, you did." "(Christine) Our Embassy economics analyst has gone insane." " That's nasty for him." " A very strong rumour is freaking him out." "Rumour being...?" "That the British Treasury have found a huge sum to improve the NHS - £13 billion." "There's a report from Moscow - blood-letting amongst the mafia." "$20 billion has disappeared in London." "World Trade Organisation money, American money." " Rumours, reports." " Yeah." "Take a brave thief to steal from the Russian mob." " What will the American government do?" " Give them another 20 billion." "I mean, we can't be seen to be losing money like that." "No, no." "You did a great service to the country." "You confronted a most dangerous man and did so with great courage." "We have recovered this." "We believe it belongs to you." "If we don't go to Egypt, I'll break this window." "Don't be ridiculous." " (Man) Major incident alarm!" " Treat this as real." " (Tom) What threat did they make?" " To bomb ten British cities." " VX." " Not the gas." " (Danny) What if it's not a drill?" " Is anyone feeling unwell?"

Many machines are mobile machines configured to perform one or more tasks while traveling over a work surface, such as a road surface. A cold planer is an example of such a mobile machine. The cold planer may include a grinding mechanism such as a rotor that grinds a top layer of the work surface as the cold planer moves in a machine travel direction. The cold planer may include a conveyor connected to a frame of the cold planer that receives the material that is ground from the road surface by the rotor. The conveyor may convey the material to another vehicle, such as a dump truck, traveling next to the cold planer. The rotor may be surrounded by a rotor housing to contain ground material from the work surface so that the material may be removed by the conveyor. A portion of the rotor extends below the rotor housing so that it can dig into the work surface. The rotor housing may include side plates that extend below the rotor housing to further retain the material ground out of the work surface by the rotor. In known cold planers, the side plate may lie on the work surface under the force of gravity and be dragged by the cold planer in a floating condition. An example of an alternative side plate arrangement is provided in U.S. Patent Appl. Publ. No. 2013/0082508 published on Apr. 4, 2013 to Orefice. In the published application, a side plate arrangement for a milling device includes a milling roller box arranged on a frame of the milling device, a side plate whose height can be adjusted and a side plate support having a swivel bearing with a swivel axis around which the side plate can swivel against the frame in a swivel area. One element of the milling device is a guide curve running concentrically to the swivel axis, with the help of which the swivel movement of the side plate around the swivel axis is carried out. Height adjustment of the side plate occurs actively through a lifting device linked to the side plate, specifically through a one cylinder piston unit. After being positioned at the desired height, the side plate skids along a work surface and rotates about a swivel axis as the milling device passes over an uneven work surface.

In a gas-phase polymerization process, traditional Ziegler-Natta catalysts have been shown to readily polymerize ethylene with one or more higher alpha-olefin comonomers such as propylene, 1-butene, 1-pentene, 1-hexene, 4-methyl-1-pentene, 1-octene and 3,5,5-trimethyl-hexene, to produce a linear low-density polyethylene (LLDPE) with minimal if any long-chain branching (LCB). The increasing development of metallocene catalyzed olefin polymers has resulted in the ability to produce similar polymers with a more well-defined molecular structure than can be achieved with conventional Ziegler-Natta catalysts . Metallocene linear low density polyethylenes made according to U.S. Pat. Nos. 5,420,220 and 5,324,800, for example, possess narrow comonomer and molecular weight distributions. U.S. Pat. Nos. 5,527,752 describes further a family of metallocene catalyst precursors which are useful, when combined with a cocatalyst or catalyst activator, in the manufacture of polyolefins. The various linear low density polyethylenes referred to above are known to be useful, among a wide variety of applications, in those applications in which a crosslinkable polymer is requited. In this vein, industry has been seeking polymers, which have improved crosslinking properties without sacrificing processability.

A powered toothbrush is designed to assist a user by mechanically moving the head of the toothbrush. One approach in the art is to provide a vibratory element in the body of the toothbrush. U.S. Published Application No. 2002/0124333 relates to a mechanical vibratory device which causes the head part to vibrate. The vibratory device is accommodated in a front head part of the toothbrush, or in a neck-part region adjacent to the head part, said neck part connecting the head part to the handle, and is operatively connected to a power source, accommodated in the handle, via electrical connections running in the neck part, vibration-damping means preferably being provided in order to prevent vibration transmission to the handle, this achieves the situation where the vibrations which effect the improved cleaning action are produced predominantly in the head part and can only be felt to a slight extent in the handle, as a result of which comfortable handling of the toothbrush is achieved. A number of approaches have been taken in the prior art to provide flexibility to the bristles during use of a toothbrush. U.S. Pat. No. 5,970,564, for example, discloses a toothbrush having an elastomeric ridge wherein there is a center array of bristles and there is a side array of bristles mounted in elastomeric boots. A number of patents disclose a toothbrush head having sets of bristles, each of which is mounted to a non-rigid or elastic support element. Examples of these approaches are found in U.S. Pat. Nos. 1,770,195, 2,244,098, 6,161,245 and 6,311,360 and in French Patent No. 38440. The head of a conventional toothbrush usually has a flat or slightly altered surface to which cleaning elements are attached. Usually the cleaning elements are strands of plastic material(s) formed into tufts, bundles or other groupings. A goal of many toothbrushes is to accommodate the cleaning element profile to that of the teeth being cleaned. Achieving that goal is complicated by the difficulty in matching a toothbrush profile to the complex surface of a typical set of human teeth. The latter generally lie in a “C” shaped curve which presents the need for a brush to address a convex outer curve and a concave inner curve. In addition, the toothbrush should be capable of cleaning irregularities on the tooth surface as well as the interproximal area between teeth. Blakeman U.S. Pat. No. 2,706,825 issued Apr. 26, 1955 discloses a replaceable bristle head for a toothbrush. The flexible head undulates in a manner so that rows of bristles move in a direction aligned with the axis of the toothbrush handle. U.S. Pat. Nos. 5,355,546, 5,483,722 and 5,839,149, all issued to Scheirer et al disclose cleaning elements mounted on a flexible membrane supported between a horseshoe shaped handle extension. U.S. Pat. No. 5,651,158 issued Jul. 29, 1997 to Hans Halm discloses a toothbrush handle with a segmented head wherein adjoining segments are linked by an elastomeric material. The segments are primarily oriented transverse to the longitudinal axis of the toothbrush but may also be oriented parallel to that axis. U.S. Pat. No. 6,088,870 discloses a latticework arrangement across the face of the toothbrush head. Tufts of cleaning elements are situated between the boundaries of the lattice and are mounted in the head so that each tuft flexes such that during brushing the bristle tufts will deflect in a manner that increases cleaning of the tooth surface. U.S. Pat. No. 6,219,874 B1 issued Apr. 24, 2001 to Gelder, et al. discloses flexible mounting of toothbrush cleaning elements accomplished by segmenting portions of the toothbrush head, which segments are connected by flexible hinges. U.S. Pat. No. 6,408,476 discloses another form of segmented toothbrush head with transverse grooves and an elastomeric portion joining the segments. A method of manufacturing this head is also disclosed. It is well known that the ideal brushing technique from a dental hygiene perspective is an up and down stroke along the vertical surface of teeth which massages the gums while cleaning the teeth. However, due to a number of factors, including ergonomic difficulties, haste, lack of education or the like, few consumers use the recommended brushing technique. Rather, the typical consumer brushes across their teeth in a horizontal motion rather than a vertical movement. Various approaches have been taken by others to translate horizontal brush movement into partial vertical movement of the bristles or cleaning elements. Translation of horizontal to vertical movement of cleaning elements is accomplished in U.S. Pat. No. 4,783,869 through use of a helix groove in a movable shaft within a toothbrush handle. The groove receives a pin which rides in the groove. This mechanism causes the toothbrush head to partially rotate or oscillate as the handle moves left-to-right or vice versa in the user's mouth. That rotation or oscillation causes the cleaning elements to move in a vertical plane perpendicular to movement of the toothbrush handle. U.S. Pat. No. 5,481,775 discloses an arcuate shaped base for a toothbrush head aligned with the longitudinal axis of the head. A movable arcuate block containing cleaning elements is flexibly mounted on the toothbrush head. The block is free to slide on the head in a manner whereby the cleaning elements may travel in a vertical direction generally transverse to the typical side-to-side motion of the toothbrush. U.S. Pat. No. 5,528,786 discloses pivotal mounting of cleaning elements that allows those elements to move up and down in concert with a side-to-side stroke along the teeth. A general disclosure of flexible mounting for cleaning elements on a toothbrush head is contained in U.S. Pat. No. 5,839,149. In this patent the cleaning elements are mounted on a flexible membrane supported between a horseshoe shaped handle extension. U.S. Pat. No. 6,141,817 discloses cleaning elements mounted on a flexible membrane that splay outward when the toothbrush is pressed against the user's teeth. U.S. Pat. No. 6,338,176 B1 issued Jan. 15, 2002 to Smith, et al. discloses round sections of cleaning bristles mounted on individual pads that rotate within a toothbrush body. This converts backward and forward motion of the toothbrush into circular motion of the cleaning elements. The bristles associated with each pad are of varying height to accommodate irregularities, gaps, pockets and contours in natural tooth formation. The rotating cleaning elements can be supplemented with fixed cleaning elements adjacent thereto. A toothbrush head should provide both proper support for the bristles, and be flexible enough during use to allow the bristles to conform to the shape of a user's mouth or teeth. Additionally, construction techniques should be inexpensive, versatile and consistent. In an attempt to meet these criteria, a process known as “Anchor Free Tufting” (“AFT”) has been used in the formation of toothbrush heads. In such an AFT process, a head plate for holding toothbrush bristles, and for eventual insertion into a toothbrush body, is typically formed of a rigid plastic that is conducive to sonic welding. The head plate is formed with a solid perimeter and defines a field of variously shaped and sized holes within this perimeter. Fibers that are to form the tufts are then placed in the holes in the field of the head plate, and the backs of the tufts are melted together to fix their position relative to one another. The tufted head plate is then inserted into a predefined receiving portion of the head portion of a toothbrush handle and is sonically welded into place. The brush is then end-rounded and packaged for sale as a traditional toothbrush. However, this manufacturing process results in a toothbrush with a very rigid head that does not easily conform to the physical characteristics of a user when brushing. Therefore, it would be desirable to provide a toothbrush that can be conveniently manufactured by the above process, but provides the desired flexibility of the head of the toothbrush during use. It would also be desirable if a toothbrush could be provided having various cleaning elements on a head, such as bristles with different degrees of flexible mounting, to have a enhanced cleaning effect when moved by a mechanical vibratory element.

Usually, the presence of bacteria in a patient's body fluid, especially blood, is determined using blood culture vials. A small quantity of blood is injected through an enclosing rubber septum into a sterile sample vial containing a culture medium. The vial is incubated at normal human body temperature and monitored for bacterial growth. Common visual inspection involves monitoring the turbidity of the liquid suspension. Known instrumental methods detect changes in the CO.sub.2 content of the culture vials, which is a metabolic by-product of the bacterial growth. Monitoring the CO.sub.2 content can be accomplished by methods well established in the art, such as radiochemical, infrared absorption at a spectral line characteristic of CO.sub.2, or pressure/vacuum measurement techniques such as those disclosed in Ahnell U.S. Pat. No. 4,152,213. Recently, non-invasive methods have been developed involving the optical interrogation of chemical sensors disposed inside a sample vial that utilize colorimetric or fluorometric spectroscopic techniques. Some of these methods have also implemented remote sensing of multiple sample sites via optical fibers and switches. Additional non-invasive optical methods have been devised which rely on properties inherent in the liquid suspension and do not require the use of a chemical sensor; these include automated techniques for scattered photon migration measurements. Typically, when using these non-invasive techniques, the sample vial must be agitated. Since it is both cost effective and time efficient to process samples in a batch, equipment must therefore be provided that agitates a large number of vials. Agitation, however, requires that the structure holding the vials moves relative to a stationary reference frame, and it is usually preferable to mount electronics and other equipment within the stationary portion of the system, not on the moving portion. This results in systems where both electrical cables and/or optical fibers must be designed to permit this relative motion by allowing sufficient excess at an appropriate point in the system. There remains a need, however, to permit a plurality of sample vials to be agitated while also permitting the interrogation of each vial by an optical fiber. It is accordingly an object of the present invention to provide an agitating rack and an optical excitation/detection system for transmitting electromagnetic energy to each sample vial in the rack and for receiving electromagnetic energy from each sample.

Associations between waist circumference and depressive disorders. Previous research has suggested that abdominal obesity and mental disorders are associated. This paper was initiated to investigate associations between unfavourable waist circumference (WC) and mental disorders in a representative sample of German adults. 4181 individuals (aged 18-65 years) took part in a physical examination (including measurement of body weight and WC) and a structured psychological interview (M-CIDI) to evaluate mental disorders. An unfavourable WC (males: 26.9%; females: 31.3%) was highly prevalent. However, unfavourable WC and mental disorders were not associated, neither with regard to the prevalence of any mental disorder nor regarding in particular depressive disorders. Moreover, even middle-aged depressive women that have often been assumed to be at high risk of increased visceral fat did not show more unfavourable WCs than their non-depressed, female counterparts. The main limitation is that the co-occurrence of mental disorders and obesity was recorded but not, if obesity was related to the onset of mental problems. From an epidemiologic perspective, it is not possible to prove associations between WC and mental disorders. Patients with unfavourable waist circumferences do not show a higher prevalence of depressive disorders.

Ghrelin receptor signalling is not required for glucocorticoid induced obesity in male mice. Chronically elevated levels of glucocorticoids increase food intake, weight gain and adiposity. Similarly, ghrelin, a gut-secreted hormone, is also associated with weight gain, adiposity and increased feeding. Here we sought to determine if corticosterone induced metabolic and behavioral changes require functional ghrelin receptors (GHSR). To do this, we treated male C57BL mice with chronic corticosterone (CORT) mixed in their drinking water for 28 days. Half of these mice received the GHSR antagonist JMV2959 via osmotic minipumps while treated with CORT. In a second experiment we gave the same CORT protocol to mice with a targeted mutation to the GHSR or their WT littermates. As expected, CORT treatment increased food intake, weight gain and adiposity, but contrary to expectations, mice treated with a GHSR receptor antagonist, or GHSR KO did not show attenuated food intake, weight gain or adiposity in response to CORT. Similarly, the effects of CORT on the liver were the same or more pronounced in GHSR antagonist treated and in GHSR KO mice. Treatment with JMV2959 did attenuate the effects of chronic CORT on glycemic regulation as determined by the glucose tolerance test. Finally, disruption of GHSR signalling resulted in behavioral responses associated with social withdrawal, potentially due to neuroprotective effects of GHSR activation. In all, we propose that blocking GHSR signalling helps to moderate glucose concentrations when CORT levels are high but blocking GHSR signalling does not prevent increased food intake, weight gain or increased adiposity produced by chronic CORT.

Prediction of Japanese children at risk for complications of childhood obesity: gender differences for intervention approaches. Childhood obesity is one of the most serious public health problems in Japan, especially in Tokushima compared with other prefectures. This study was designed to clarify the life habits which predispose to development of obesity and can be modified through an appropriate intervention program to combat childhood obesity and its lifestyle-related diseases. A total of 216 school children from Itano Town, a municipality of Tokushima Prefecture, Japan, who are attending the fourth grade (9-10 years) of elementary schools, participated in the study from 2004 to 2007. The study included child's life habits questionnaire, investigating physical activity by recording the daily steps using a pedometer, anthropometric measurements, hematological examination and hemodynamometry in a cross-sectional survey during a two-month period from June to July every year. We conclude that there are considerable gender-related differences for developing obesity and other lifestyle-related diseases; and all intervention strategies against obesity must consider such gender differences. For example, restriction of television watching hours must be intervened for controlling obesity in boys, however for girls, promotion of exercise practice or making more steps per day with adequate sleeping periods should be intervened as the proper approaches for preventing and controlling obesity and other lifestyle-related diseases.

Open acromioplasty does not prevent the progression of an impingement syndrome to a tear. Nine-year follow-up of 96 cases. We performed open acromioplasty for intractable impingement syndrome on 96 shoulders (93 patients) with an intact rotator cuff. All the shoulders were examined by ultrasound after a mean interval of nine years. Those showing pathological findings, a poor or fair subjective result, or deterioration of the primary excellent outcome had MRI and/or arthrography. The mean Constant score for the affected shoulders was 70 points and that for 48 non-involved, symptom-free shoulders, 84 points. The subjective outcome was excellent in 45, good in 24, fair in 18 and poor in 9 shoulders. Complete tears were found in 12 shoulders and partial tears in seven. A total of 14 shoulders was symptom-free after acromioplasty, but after an average of five years became painful again and showed deterioration. Of these, six had complete tears and four partial tears of the cuff. The tear rate was 4% in shoulders initially judged to be excellent, 25% in good, 33% in fair and 55% in poor shoulders. The tear rate was 71% in shoulders which subsequently deteriorated. The incidence was higher in men (25%) than in women (11%). We conclude that a tear of the rotator cuff may appear after acromioplasty, although there was no evidence of a tear at the time of operation. This is usually the reason for deterioration in a shoulder with an initially good operative outcome.

"This line." "All the good candy is gonna be gone." "Come on." "Taking candy from babies now, eh?" "Hey, hey, I'm eight months clean." "If that's what it takes..." " What's this festival about anyway?" " Drinking." "I thought it was to honor the patron saint of..." "Drinking." "Thought they'd cancel it this year with all the rain." " Can you believe that storm last night?" " I slept right through it." "Ryan sleep through it?" "I wouldn't know." "How about Zee?" "How did she do?" "Maybe the patron saint of mind- your- own- business." " Sounds about right." " Yeah." "Hey, no cutting in line." "I gotta go get supplies." "You're on your own, mate." "Pata de vaca, cow's hoof." "Lowers blood sugar in diabetics." "Without the risk of what, doctores?" "Hypoglycemia, a side effect of all Western diabetes medications." " Very good, Dr. Brenner." " Why hasn't it caught on?" "What American is gonna walk into a pharmacy and ask for a 30- day prescription of cow's foot?" "Muira puama, potency wood." "A very potent male aphrodisiac." "Dr. Clark." "What's up?" "Used to treat erectile dysfunction." "I don't need that." "Can you ask your boyfriend where all the sick people are?" " Because I'm dying here." " He is not my- " "I already asked him and he said the clinic would be pretty dead during the festival." "Well, how long does the festival last?" " Three days." " Ladies." "Amor seco, natural antihistamine." "Didn't you use that on the farmer having an allergy attack?" "You read my book, Dr. Brenner." "Twice, actually." "I don't know how you read it once." "It was boring as hell." "Are you kidding?" "The part about using army ants to close a wound?" "That was- " "I taught you the ant trick." "Funny you didn't put that in your little book." "Car crash, way up in the mountains." " Oh, thank you, God!" " Probably the roads are flooded." " They say how many are injured?" " Didn't say." "Fuller, Brenner, let's pack up." "I'll go get Ryan." "Don't worry about me." "I'm fine." "Look, breathe it out, mi amor." " How far apart are the contractions?" " Sweet mother of- " " Not far." " This cannot be happening." "We were on our way to the airport." "Were gonna fly sooner, but we're in the Peace Corps." "Had to finish rotation." "Supposed to be having the baby with my family in New York." "I'm afraid that's not gonna happen." "Even minor accidents can jump- start labor and you're well on your way." "We gotta get you to the clinic." "Okay, change of birth plan." "I can roll with it." "You?" "Okay." " It hurts." " Oh, wait, your iPod, it's in the truck." "No, Roberto, leave it." "It's fine." "But it's got all your birthing music." "Worked my ass off making that mix." "Wait, Roberto!" "Wait, wait, stop!" "Robbie!" "Robbie!" " I'm okay!" " Robbie!" " I'm okay!" " Robbie?" "Okay, I need you to wiggle your toes for me." "Distal neuro- circ intact." "Can you breathe?" "Femur is broken." "That's a massive tree." "There's no way we're gonna move that without a pulley." "She's in active labor, three minutes apart." "We can't wait." "We gotta get her back now." "Please, don't worry about me." "Just take care of Syd and the baby." "Push four of morphine, a liter of saline." "I'm gonna send a rescue team as soon as we're back." "No!" "I'm not leaving without him!" "Look, I'll be right behind you, baby." "Just remember what the baby books said." "I never read the baby books." "Okay, okay." "Forget them." "Look, you can do this, Syd." " Look, don't worry, okay?" " Okay?" "We'll get him back to you." "You can do this." "Okay." "Look, it's our first kid, she's nervous and she apparently didn't read the baby books." "So if you like your colleagues, you'll get me out of here fast." "What are you doing?" "You guys don't have a filing system, so I'm setting one up." "You know most hospital error is caused by inaccessible medical records?" "We had a system." "It was my system." "Okay." "So then why is Ruiz before Peña?" "Because there are over a hundred patients here by the name of Peña." "It's not alphabetical, it's by village." "Oh, yeah, smart." "Okay." "Why don't you just go take the night off?" "Hit the festival, connect with the community." "That's half of what practicing medicine here is anyway." "Partying isn't gonna make me a better doctor." "No, but it just might get that stick out of your ass." "Oh, my God." "Is that still a contraction?" "Okay." "I was gonna read the books." "I was." "I just figured that since I thought Roberto would be here with me, that he could give me, like, a CliffsNotes version of them." "It's just what we do." "I impulsively get things, like babies and electronics, and he reads the instructions." "It's just that he's the prepared one." "He set up this whole amazing birth plan with- " "Baby looks good." "Normal cephalic lie." "" " Music and aromatherapy- " "Americans and their birth plans." "The plan around here is to squat in a bush and get back to work." "Baby's heart rate is dropping, 90." "Late decels." "Let's get her on her side." "Five liters of oxygen." " What's going on?" " The baby's heart rate is decelerating after you contract." "He's not tolerating labor." "Means that we're gonna have to do an emergency C- section, okay?" "Oh, God." "I'll tell him." "Thanks, Lily." "Good news." "Your rescue team is on its way." "And they're battling muddy roads, but they'll be here." "Wait, how's Sydney?" "The baby's heart rate is dropping, so, Sydney is gonna need a C- section." "Oh, God, she must be freaking out." " You gotta get this thing off me." " No, hey, look." "The rescue team are gonna have this big pulley system." " They're gonna get this thing- " " Screw that." "Let's rescue ourselves." "What, did you just cut a tree down with a machete?" "What tree?" "It's a lever." "Help me out." " All right, let's do this." " Okay." "Okay, let me get that." "All right." "Lever time." "You have to take off your shirt to move a tree?" "It's really hot here." "You push down on the lever, I'll get Roberto." " Okay." "Okay, ready?" " Hey." "All right." "Easy, easy." " On three, ready?" " Ready." "One, two, three." "Got him." " Splint the femur." " All right." " There you go." " All right." "We're gonna make it out, sí?" "Well, I didn't wanna say anything, but missing your wife give birth is like years of free back rubs." "Pulmonary hemorrhage." "Get suction." "Looks like you took a blow to the chest on your way down the hill." "That why it hurts when I breathe?" "Yeah, it's called a pulmonary contusion." "The trauma you took to your chest is causing bleeding in your lungs." "We need to get you back to the clinic and put you on oxygen." " I'm gonna go call the rescue team." " Yeah." " You like her." " What?" "L" " I like a lot of girls." "You must be cleaning up down here." "This place is kind of awesome." "There's hot doctor chicks, hot tourists coming in almost every single day." " It's kind of great." " An all- you- can- eat international buffet." "Exactly." "I used to be like you, hermano." "I was a lawyer in Mexico City." "Made some money, came down here." "All I did for a year was surf and screw." "Sounds awesome." "See, I was free, but I was aimless." "I used to be terrified of being tied down." "What I got in return?" "So much better." "It's amazing." "Finding that person you wanna give your whole life to." "Sydney?" "Sydney saved me." "Gave me purpose." "And I never even saw her coming." "You were at the buffet, she was on the special à la carte menu, you know?" " Hey, that's my wife you're talking about." " Sorry." "Question." "Okay, English is not my first language, but I'm sure that was a statement." "Which one of your weird- ass plants will make a sorority chick's hangover even worse tomorrow?" "Festival casualty." "You know, I was thinking that maybe we could stop by later." "Or tomorrow, if you want." "Like a real date?" "You getting serious on me now?" "Call it whatever you want." "I just like to dance." "Yeah, see, parties full of debauchery and drinking aren't exactly the best environment for me." "But you go and rumba your little ass off with all the lobos you can find." "I'm not the jealous type." "No more questions." "I've got surgery." "Have we heard from the rescue team yet?" "I feel like Roberto should be here by now." "Well, the roads are still flooded, mi vida." "It's slowgoing." "It'll take them a while to get back." "I just can't believe he's missing this." "You know he even prepared for a C- section?" "He said that it wouldn't happen, but if it did, that he would talk me through it every step of the way." "You know what?" "Fear of surgery is a lot like fear of flying." "If you know what the pilot is doing, that the turbulence is normal, then it's much easier to sit back and order a cocktail, right?" "I'm gonna tell you everything we're doing, okay?" "Every step of the way." "Brenner, this is not a football game, running commentary while the patient is on the table." "Well, I really think it would help her." "Your patient, your call." "Hey, blondie." "What's up?" " You're sounding like Tommy now." " Yeah?" "Cool." "It's not a compliment." " Want some cuy?" " No." " It's a delicacy." " No, it's full of parasites." "No." "I really thought Americans loved to travel and eat weird stuff." "No, this American likes to work, but I've been placed on a time out." " A doctor time out." " Yeah." "Whoa, watch it." "You must be the life of the party back home." "No, I don't really go to parties." "Pork sandwiches." "Oh, I hope they're using a meat thermometer." " I just had one." " Well, you just had a brain cyst on a bun." "Okay, I need a time out." "Time in." " Suction." " Noisy electric Band" " Aid." " What's going on now?" " The grid must have blown." " Zee, tamponade." "Brenner, here." " Where are you going?" "Open wound here." "Apply pressure to the incision." " I can barely see anything." "L- " " Get in there and squeeze!" "Come on, come on." " You piece of- -!" " Cole!" " Cole, I need your help!" " Lord, grant me the serenity." " He's saying he lost something." " Probably his wallet." "He's got bigger things to worry about." "He got hit by a high- powered DC current entering the leg and exiting the chest." " Explains the power outage." " Exit wound caused his shirt to set on fire." "Got third- degree burns, increasing respiratory distress." "What's that smell?" "Is that the burn?" "No, that's the taco meat." "Hey, you said get a stretcher." "It was the best I could do." "Festival blew the grid, fried our generator, but it should be going again soon." "Fetal heart rate is 140." "We're good to continue." "Any news on Roberto?" "The rescue team radioed in while I was out there." "Unfortunately, they never made it." " The truck got stuck a couple of miles out." " So he's still out there?" "He's got two excellent, capable doctors with him." "He'll be fine." "They just might take a while." "It's cold and it's dark and he's hurt." "And he's just laying out there on the side of the road." "Oh, my God." "This is crazy." "BP is way up, 150 over 95." "Sydney, it's not safe to operate if you don't calm down." " Please." "I don't even know if he's okay." " Sydney, Sydney." "What if we tried to get him on the radio?" "You could at least hear his voice." "It could calm her down." "Please." "Then we gotta move." "We gotta get this baby out." "It's okay." "It's okay." " He's barely breathing." " The burns have scarred his skin." "His chest can't rise." "He needs an escharotomy." " What's that?" " We cut through the burned skin" " to relieve the pressure." " Betadine, cutdown tray, two scalpels." "Get out of here." "You don't wanna see this." "Yeah, I do." "All right, fine, but face the wall and don't peek." "Now listen, you're gonna go lateral and inferior." "Ready?" " Will it hurt?" " No, he won't feel a thing." "He's burned off all of his nerve endings." "Did I say turn around, Charlie?" "He took a jolt big enough to blow the town generator." "I can't believe it didn't kill him." "It's crazy it didn't kill him." "Instead of wondering why it didn't kill him, let's make sure it doesn't, okay?" "He's still saying he lost something." "Pulse ox is 78." "He's drowning on his own secretions." "Where the hell is the rescue truck?" " It's not coming." " They're coming." "They went off the road." "It's gonna be a while." " He'll pass out soon." "We have to bag him." " I know." " Is the truck here?" " No." "I'm gonna tell you what's gonna happen." "It's gonna get a little harder to breathe." "And then you're gonna pass out, but that's okay, because we're gonna breathe for you." "And when you wake up, you're gonna be at the clinic with your wife and your son." "Max." "His name is gonna be Max." "That's a great name." "No, it's not." "I wanted Diego." "That's a great name." "But since I'm missing the whole thing," "I guess the woman should probably get her way." " There it is." " All right." "All right, I'm in." "Okay." " Yeah." " Clark." "How's the patient?" "His wife wants to talk to him." "That's not gonna happen." "He's in respiratory failure from pulmonary contusions." " We took his airway." " Great." "It's all we could do, Ben." "Look, until the rescue team gets here with the truck..." "It doesn't look good." "Hey, listen, did he say anything?" "Something that I can pass on to Sydney?" "Max." "He said Sydney could name the baby Max." "Why?" "Did you reach them?" "He did wanna talk to you, but we lost the signal." " Is Roberto okay?" " He's not the happiest camper right now." "You know, it's pretty chilly out there and he's got one broken leg." "But he did say you could name the baby Max." "He did?" "He's been fighting me on that one for nine months." "What do you say we get this show on the road, then?" " So your husband can meet Max." " Yeah, thank you." "So everything is...?" "Fine, yeah." "Everything is fine." "Let's do this." "Say good day to Max." "Hi, baby." "Hi, Max." "You have a beautiful baby boy, Sydney." "What's wrong with his skin?" "Bilirubin has got to be over 30." "I'm starting an umbilical line." " What's wrong with him?" " He's severely jaundiced." "He may need a transfusion, Sydney." "Can you take over?" "Your baby is gonna be okay, Sydney." "We just- " "Sydney?" "She's losing consciousness." "God, she's bleeding out." "Okay, massage the uterus." "Use 20 of PIT." "We don't have suction without electricity." " Well, we'll use lap pads then." " Will that be enough?" "It has to be." "We don't have a choice." "Pulse ox is up to 94." "Kid is exhausted, but he's getting air." "There's gotta be something going on with this guy." "Anybody else would be a fried chicken right now." "I'm gonna run a differential and then- " "You didn't shock him so you could come back to work, did you?" "Hey, had to ask." "All right." "He wants to go back to the festival." "I lost- " "The love of my life." "Okay, sir, you're very sick." "Just try and relax." "I have seen her every year at the festival." "She's linda." "Beautiful." "Always wearing blue." "He says he's like Peter Parker with no spider powers?" "I think he's delirious." "Yup." "He's running a fever." " And he's got a crazy low heart rate." " Have you talked to her?" "Last year, he finally got up the courage to talk to her." "They talked for hours about comic books." "They fell in love." "But when he went to go buy her a drink, he lost her in the crowd." "What's her name?" "I never ask." "Well, that was dumb." "I'm more concerned about your fever and your low heart rate." "So I'm gonna run an EKG, okay?" "Okay." "That one doesn't have a single romantic bone in her body." "B" " Lynch sutures in place." " It looks dry." " Yeah, I think we got it all." " How's the baby?" " Not good." "He's headed for brain injury or death without an exchange transfusion." " He's B positive." "So is Sydney?" " Yeah, but she lost half her blood volume." " She needs a transfusion herself." " Have any B pos?" "Not enough." "We need a live donor." "The father." "If Sydney and Max are both B positive, then he should be compatible." "Sí, and since he's a relative, the baby is less likely to have a transfusion reaction." "Sounds like our best shot." "It's our only shot." " Absent doll's eye sign." " Try a corneal." "Pulse ox is 55." "He's brain- dead." "This was all we could do." "Time of death, 23:30." " Yeah?" " Clark." " How is he?" " We called it." "Damn it." " How long ago?" " Less than a minute." "Does he still have a pulse?" " What?" " Pulse!" "Does he still have a pulse?" "What- -?" " Yeah, yes." " Okay, start bagging him again." "Bring him back." "Keep his heart beating." "Don't wait for the truck." " Carry him." " We're miles away." "That will take all night." " Just get him back here." " Why?" "His wife and kid, they need his blood." " Bag him." "Bag him." " What?" "He's dead?" "Yeah, respiratory failure a few hours ago." "He never had a chance." "But his heart's pumping, so the blood should be usable." "A few hours ago?" "You mean before surgery?" "You said he was fine, that he just had a broken leg, that he would be here to meet his baby." "Told her what she needed to hear to get through surgery." "Oh, well, what do we tell her now?" ""I'm sorry, but your husband is dead and you and your baby both need his blood to survive"?" "That sounds about right." "Oh, my God." "Poor Sydney." "Look, if it had to happen, it's good that it happened like this, okay?" "How is it good?" "Look, the guy is brain- dead, all right?" "There's no gray area here." "There's no hooking him up to a machine and hoping he recovers." "She can move on with her life, put it away." "Now I'm gonna go see if she's up." " Are you coming?" " I can't believe you." "I thought I..." " Fine, I'll go tell her myself." " No." "No- " "I'm gonna tell her." " My patient, my call." " Hey- " "Are you sure this is the right road?" "I can't see a damn thing." "It's almost dawn and we've only got about 10 more miles to go." "I didn't need to know that." " Hey." " Hey!" "Hey." "Hey!" " Stop!" " I don't think they're gonna stop." "Hey!" "I don't think they're gonna- " "Hey!" "There." "They stopped." "I feel you, hermano." "There's this girl, smart, beautiful, nice to everyone." "I don't even think she knows my name." "Trust me, you have to tell her." "Splenomegaly." "Enlarged spleen." "Write that down." " What's going on?" " Heart rate is 49." "BP is only 60 palp." "Push atropine." "Man, his pupils are normal." "What the hell is going on with this guy?" "Enlarged spleen, fever, bradycardia." "What causes that?" "Mosquitoes, sandflies, parasites..." "He says he sometimes sits by the river, watching the water taxis go by, looking for the girl." "Enough with the romance novel." "I'm trying to save his life." "Aren't there more mosquitoes by the river?" "Don't they spread diseases?" " Hold this." " What are you doing?" "I told you, saving his life." "What happened?" "How's the baby?" "Max is sick, Sydney." "He needs a blood transfusion." "And so do you." "You've lost a lot of blood." "Where's Roberto?" "Is he here?" "Roberto suffered chest trauma." " His lungs filled with fluid." " What?" "They did everything they could." "His brain couldn't get enough oxygen and last night he had a stroke." "And the thing is, they kept his heart beating, because his blood is a match for you and Max and you both need it very badly." "I'm sorry, I don't..." "What are you telling me?" "Are- -?" "Is my husband dead?" "Yes." "And you wanna put his blood inside me?" "Yes." "Oh, my God." "Oh, my God." "I know I promised you that I would tell you everything." "And I didn't, but now I am." "You and your baby, you both will die without this transfusion." "Save the baby, then." "Let me die." " I can't do it." " I won't let you." " Get out." " Sydney- " "I said get out." " Please- " " Get out!" "Get out, go." "Get the hell out of here!" "Get out!" "Get out!" "Great news, Jorge." "I looked at your blood work." "You've got malaria." " I don't think he gets it." " He gets it." "I get it, but how is that great?" "Because it's a unique strain called vivax." "A small percentage of people who get it develop a low heart rate." "So low, in fact, that the electric current that hit you hit between heartbeats and it didn't stop your heart." "Now, it also causes an enlarged spleen, which could've exploded and could've killed you." "So as I see it, you were meant to die twice over and didn't." "You lucky man!" "Forget the blue dress." "This is your money story." "He's not lucky." " What?" " He's 22 years old." "He's had three broken arms, four broken toes." "Yesterday, he missed finding the love of his life, because he got electrocuted, and today he has malaria?" "He is not lucky." "Sorry." "Perhaps "lucky" was the wrong choice of words." "But I'm gonna fix you." "Just promise me that at the next party, you're gonna get the chick's name." "How is she?" "Well, we gave her iron to bring up her counts, but she still won't consent to the transfusion." "Sydney." "I'm Dr. Fuller." "I was in the field with your husband." "I remember." "You said that you'd bring him back to me." "I've been trying and she's just not ready, okay?" "So you should go." "I did." "What?" "I did bring your husband back to you." "All he wanted was to come back to you and now he's here." " And it doesn't have to be for nothing." " Stop." "No, look, that guy loved you so much that it was crazy." "The way he talked about you," "I don't even know what it's like to feel that way about a person." "And the last thing he would want right now is for you to give up, because that would mean you're giving up on him." "I'm so sorry that I could not save Roberto." "I am so sorry that he's never gonna get to meet his son, because he was so psyched to be a dad." "But what he's doing right now for Max, that is being a dad." "He told me that you saved him." "Let him save you." "I don't know how to do it." "I don't know how to live without him." "I know." "It's not easy." "But you just do." " Hi." " Hi." "You know my name, right?" "Yeah, Charlie." " I'm just checking." " Okay." "Yes." "Vivax malaria." "Finally found your infectious disease." "Yeah, I guess I did." "But you acted like an addict doing it." " What?" " You had a few hours yesterday with nothing to do, and you couldn't handle it." "Your mind starts spinning, your palms get sweaty, your skin starts itching." "Am I close?" "No." "No, actually I just like to work." "It's not work." "It's penance." "What was his name?" "The kid you misdiagnosed back in the States." "We all got one." "Eric." "PFC Marcus O'Grady." "I was a medic when I started using and..." "The work doesn't help." "Doesn't make you forget." "So, what does?" " Come on." " Why?" "Where are we going?" "To that stupid party." "Even the damned deserve a night off." "See you." "I thought you weren't coming." "Come on, loca." "Show me what you got." "Wait, wait, wait." "So then this guy stopped!" " Oh, God!" " Right in front of her face." "She's a superhero, this chick." "Yeah, well, I have my kryptonite." "Whatever." "This is officially the festival of Ryan's giant balls." "Thanks." "Don't worry." "No one else is gonna drop dead." "The pork is cooked." "Lots of girls wear blue, blondie." "Señorita." "Señorita?" "Yeah, okay, ask her if she knows Jorge." "No, wait." "If he didn't know her name, then she doesn't know his." "Ask her if she's waiting for her Peter Parker." "Yeah, I know." "Just do it." "He's waiting for you." "Here, la clínica." "Tell her that he's a real superhero." "He escaped death twice." "See?" "I mean, I listen to some stuff." "Oh, come on." "Please, give me a break." "I'm trying to be good here and- " "Oh, you work here." "I'm sorry, I thought you were trying to hit on me, and I'm just- " "No inglés." "Oh, well, no español." "Except hola." "It was a rough one today." "Yup." "How was Keeton?" "With the patient, was he okay?" "Well, he was not who I thought he was." "He lost his wife and kid a few years back." "The accident last night hit pretty close to home, so..." "Go easy." "Abby."

1. Field of the Invention The present invention relates generally to a semiconductor laser device used for reproducing information from optical disks with different formats, such as a compact disk (CD) and a digital video disk (DVD), in a single optical pickup device. 2. Related Background Art Currently, the CD market is the largest market among the optical disk markets. In the device for reproducing information from CDs, a near infrared semiconductor laser element with a wavelength in a 780 nm to 800 nm band has been used. On the other hand, for recording and reproduction with respect to DVDs, which are optical media with higher recording density and are expected to come into wide use rapidly in the future, a red-color semiconductor laser element with a shorter wavelength in a 635 nm to 680 nm band has been used, since a light spot is required to have a small diameter. It has been requested to enable information to be recorded and reproduced with respect to two such kinds of optical disks with different standards in one device. An optical pickup device for such a purpose is described, for example, in JP 10(1998)-320815. FIG. 9 shows a configuration of a conventional optical pickup device. An operational principle of the conventional optical pickup device is described with reference to FIG. 9 as follows. For recording and reproduction with respect to a CD, a semiconductor laser element 101 with a wavelength of 780 nm is used. A beam 116 emitted from the semiconductor laser element 101 in the direction perpendicular to the surface of an optical disk 106 is diverged into three beams by a diffraction grating 115. A collimator lens 103 disposed on an optical axis converts the divergent beam into a parallel beam. The parallel beam goes through a wavelength deflection filter 109 and is focused on the optical disk 106 by an objective lens 105. The beam reflected by the optical disk 106 is converted from a divergent beam into a parallel beam by the objective lens 105 and goes through the wavelength deflection filter 109 again. Subsequently, the beam is converted into a converged beam by the collimator lens 103 and then enters a hologram element 111. The beams divided by the hologram element 111 are detected as electric signals in receiving optics 113. Based on the detected signals, the reproduction and focusing/tracking servo are carried out with respect to the CD. On the other hand, for recording and reproduction with respect to a DVD, a semiconductor laser element 102 with a wavelength of 635 nm (or 650 nm) is used. A beam 117 emitted from the semiconductor laser element 102 in a direction parallel to the surface of an optical disk 106 is converted from a divergent beam into a parallel beam by a collimator lens 104 disposed on an optical axis and goes through a polarization beam splitter 107 and a xc2xc wavelength plate 108. Subsequently, the beam is reflected by the wavelength deflection filter 109 so that its path is deflected by 90xc2x0, and then is focused on the optical disk 106 by the objective lens 105. The beam reflected by the optical disk 106 is converted from a divergent beam into a parallel beam by the objective lens 105 and is reflected by the wavelength deflection filter 109 again so that its path is deflected by 90xc2x0. Subsequently, its polarization direction is changed by the xc2xc wavelength plate 108. Therefore, the beam entering the polarization beam splitter 107 is reflected so that its path is deflected by 90xc2x0, and then is converged by a detection lens 110. The converged beam goes through a cylindrical lens 112 and is detected as an electric signal in receiving optics 114. Based on this detection signal, reproduction and focusing/tracking servo are carried out with respect to the DVD. In the above-mentioned configuration, the semiconductor laser with a wavelength of 780 nm is mounted and therefore recording and reproduction also can be carried out with respect to CD-Rs. However, such a conventional optical pickup device as shown in FIG. 9 is configured with many optical components such as two semiconductor laser elements 101 and 102 with different emission wavelengths and a plurality of receiving optics 113 and 114 for respective beams emitted from the semiconductor laser elements 101 and 102, as well as the hologram element 111, the cylindrical lens 112, the wavelength deflection filter 109, and the like. Therefore, it is difficult to reduce the size of the device. Moreover, since the respective optical components are disposed discretely, a lot of positional adjustments and fixation are required, and thus great amounts of time and cost are required for the assembly, which have been problems. Therefore, the present invention was made to solve the aforementioned conventional problems. The present invention is intended to provide a small and inexpensive semiconductor laser device capable of carrying out recording and reproduction with respect to various optical disks with different formats and to provide an optical pickup device having the same. In order to achieve the above-mentioned object, a semiconductor laser device according to the present invention includes a receiving/emitting optics integrated substrate and an optical element. In the receiving/emitting optics integrated substrate, a first semiconductor laser element, a second semiconductor laser element, and a plurality of receiving optics are integrated on a substrate. The first and second semiconductor laser elements have different emission wavelengths. A distance L1, when measured in air, from the first semiconductor laser element to a focusing member is substantially equal to a distance L2, when measured in air, from the second semiconductor laser element to the focusing member. According to this configuration, the two semiconductor laser elements and the plurality of receiving optics are integrated in the receiving/emitting optics integrated substrate, so that a small and inexpensive semiconductor laser device can be provided. In addition, since the distances, when measured in air, from the two semiconductor laser elements to the focusing member are substantially equal, one single focusing member (for instance, a collimator lens) can be employed. Thus, the optical configuration is simplified. In the semiconductor laser device according to the present invention, preferably, a difference between the distance L1 and the distance L2, when measured in air, is within xc2x150 xcexcm. According to this configuration, particularly the influence of aberration can be suppressed to a low level and it becomes easy to configure the optical pickup device employing a single focusing member. In the semiconductor laser device according to the present invention, preferably, the optical element is disposed in an optical path at least between the first or second semiconductor laser element and the focusing member. This configuration enables return light from the optical disk to diverge efficiently to be lead to the receiving optics. In addition, it is preferable that the optical element includes a member allowing a distance for which a beam emitted from the first semiconductor laser element travels to go through the optical element to be different from a distance for which a beam emitted from the second semiconductor laser element travels to go through the optical element. According to this configuration, the distances for which the two emitted beams travel to go through the optical element are made different, so that the distances, when measured in air, for which the two emitted beams travel after leaving the optical element can be made substantially the same. It also is preferable that a light diverging member is formed in the optical element and a diffraction grating, a reflector, or the like is used as the light diverging member. In the semiconductor laser device according to the present invention, preferably, the first semiconductor laser element has an emission wavelength in a 780 nm band, and the second semiconductor laser element has an emission wavelength in a 650 nm band. According to this configuration, recording and reproduction can be carried out with respect to optical disks with both the CD format and the DVD format. Preferably, the light diverging member exhibits different diverging efficiencies depending on wavelengths. According to this configuration, for example, when a diffraction grating is used as the light diverging member, a semiconductor laser device can be obtained which has light diverging efficiencies optimized with respect to respective wave lengths through adjustment of the depth of the diffraction grating. When using this, therefore, an optical pickup device with excellent light utilization efficiency can be configured. Consequently, a low power consumption type optical pickup device can be obtained. Furthermore, in the semiconductor laser device according to the present invention, it is preferable that the substrate is a silicon substrate with a principal plane that is a plane obtained when a plane equivalent to a plane (100) is rotated about an axis extending in a direction equivalent to a direction less than 0-11 greater than by 5xc2x0 to 15xc2x0 in a direction equivalent to a direction less than 100 greater than , concave portions are formed in the substrate, the first and second semiconductor laser elements are placed on bottom surfaces of the concave portions, and each beam emitted from the first and second semiconductor laser elements is reflected by one side face of the corresponding concave portion. According to this configuration, when the concave portions are formed at the surface of the silicon substrate by anisotropic etching using a potassium hydroxide-based etchant, a plane equivalent to a plane (111) can be formed as one of side faces of each concave portion, having an angle of 40xc2x0 to 50xc2x0 with respect to the bottom surface of the concave portion. Therefore, when the first and second semiconductor laser elements are disposed on the bottom surfaces of the concave portions, the one of side faces of each concave portions serves as a reflecting mirror and thus emitted beams can be lead out upward in the direction substantially perpendicular to the silicon substrate. Furthermore, the plurality of receiving optics are formed in the area where the concave portions are not formed, so that the receiving/emitting optics integrated substrate can be configured easily. In the semiconductor laser device according to the present invention, it is preferable that the receiving/emitting optics integrated substrate and the optical element are disposed in one case. According to this configuration, a plurality of elements can be disposed in one case and the whole is sealed, so that the reliability can be improved easily. In addition, when this case is formed as one optical unit, its handling in the assembly of an optical pickup device is considerably easier as compared to the case where separate elements are handled. Thus, the assembly process and line can be simplified. In order to achieve the above-mentioned object, an optical pickup device according to the present invention includes a focusing member and a semiconductor laser device provided with a receiving/emitting optics integrated substrate disposed in a case, and an optical element. In the receiving/emitting optics integrated substrate, a first semiconductor laser element, a second semiconductor laser element, and a plurality of receiving optics are integrated on a substrate. The first and second semiconductor laser elements have different emission wavelengths. The optical element is disposed in the same case as that including the receiving/emitting optics integrated substrate. A distance L1, when measured in air, from the first semiconductor laser element to the focusing member is substantially equal to a distance L2, when measured in air, from the second semiconductor laser element to the focusing member. The focusing member is positioned to be fixed to the case of the semiconductor laser device. According to this configuration, the assembly process and line of the optical pickup device described above can be simplified. Preferably, the optical pickup device according to the present invention further includes a supporting member, and the case and the supporting member are connected by a supporter, and the case is movably semifixed to the supporting member. According to this configuration, all the optical components of the optical pickup device are integrally movable. Therefore, when the focusing/tracking servo is carried out with respect to an optical disk, no optical shift is caused and thus reliable recording and reproducing characteristics can be obtained. In the semiconductor laser device according to the present invention, preferably, the first and second semiconductor laser elements are integrated in one chip. According to this configuration, a plurality of semiconductor laser elements are integrated in one chip, so that a semiconductor laser device with a reduced number of components can be obtained. This enables the size of the optical pickup device to be reduced. In addition, in the semiconductor laser device according to the present invention, it is preferable that the optical element is placed on the receiving/emitting optics integrated substrate. According to this configuration, the optical element is placed on the receiving/emitting optics integrated substrate, so that a semiconductor laser device with a protected receiving/emitting optics integrated substrate can be obtained. Consequently, the reliability of the optical pickup device can be improved.

Analysis of pipelines in-situ is an important function that, unfortunately, is not readily achievable with conventional technology. In order to investigate pipelines, such as for defects within the materials of the pipeline, the pipelines must be readily accessible for visual/material inspection. Pipelines that extend underground, therefore, must be uncovered so that investigators may visually identify the surface of the pipe. Removal of the overburden from a pipe is a difficult and dangerous situation for work crews that are tasked with the function. To this end, the progress of analyzing pipelines is a costly proposition that also involves a safety concern of investigators. Pipelines that have changes in geometry, such as elbows, moreover, cannot be readily evaluated even by remote methods. Changes in geometry of a pipeline necessitate both direct visual inspection by inspectors and the ability to touch the pipeline in the area of concern so that material investigation can begin. Such access to the piping system may be impossible in certain circumstances, so these piping systems go uninspected. These significant drawbacks of conventional systems cost excessive money to be spent by pipeline owners who desire to carefully maintain their equipment to a desired standard. In light of the drawbacks presented above, there is a need to provide for a pipeline inspection system that is mobile and is economical to use. There is an additional need to provide a pipeline inspection system that can account for changes in geometry of the pipeline so that the pipeline may be remotely inspected. There is an additional need to provide a pipeline inspection system that will account for various environmental and construction factors, such as a coating on a pipe. There is a further need to provide a pipeline inspection system that will allow an investigator to pinpoint defects in a pipeline or analyze more closely a selected area of a pipeline desired by investigators.

Semantic organization of study materials has opposite effects on recognition and recall. It has been well established for several decades that semantic organization of study materials greatly enhances recall by facilitating access to information during retrieval. However, the effect of organization on recognition, and its relationship to the effect on recall, is in doubt. We report the first direct comparison of the effects of categorically organizing study lists on recognition, cued recall, and free recall. We found that whereas organization improved recall, it impaired recognition. Organization had a larger effect on free recall than on cued recall. Within the categorized lists, recall was superior for items highly associated with the category; the opposite was true of recognition. In recall, organization improved the proportion of categories recalled, but it lowered the proportion of items per category recalled. A simple framework for interpreting the dissociation is offered. Possible mechanisms underlying the detrimental effect of organization on memory and prospects for future research are briefly discussed.

Endogenous hormone levels in habituated nucellar Citrus callus during the initial stages of regeneration. Embryogenic nucellar callus cultures of different Citrus species and cultivars growing in hormone-free medium were transferred to medium containing either sucrose or glycerol as the only carbohydrate source. Glycerol has been reported to induce further development of Citrus somatic embryos, while in the presence of sucrose they continue to proliferate in an 'undifferentiated' manner. The endogenous hormone levels of the cultures were evaluated after 2 and 5 days to characterise the initial steps of embryo development. In most cases, differences among treatments were observed only after 5 days of culture. Higher cytokinin levels were found in most of the cultures transferred to the glycerol-containing medium. The effect of ageing sweet orange cultures on their endogenous hormone levels was determined by leaving them in the original culture medium without subculturing for 60 days. While no changes were observed in the free indoleacetic acid and gibberellin contents, lower levels of abscisic acid and cytokinins were found in the aged cultures than in those transferred at the normal interval, every 30 days. The endogenous hormone contents of Citrus callus of different genotypes were compared. Significant differences were observed in the levels of all hormones evaluated, even when the in vitro ontogeny of the different genotypes was very similar.

The present invention relates generally to applying a super-conducting coil to a high power density synchronous rotating machine. More particularly, the present invention relates to a synchronous machine with a conventional stator, and a magnetically saturated solid iron core rotor having a super-conducting coil. Synchronous electrical machines having field coil windings include, but are not limited to, rotary generators, rotary motors, and linear motors. These machines generally comprise a stator and rotor that are electromagnetically coupled. The rotor may include a multi-pole rotor core and one or more coil windings mounted on the rotor core. The rotor cores may include a magnetically-permeable solid material, such as an iron-core rotor. Conventional copper windings are commonly used in the rotors of synchronous electrical machines. However, the electrical resistance of copper windings (although low by conventional measures) is sufficient to contribute to substantial heating of the rotor and to diminish the power efficiency of the machine. Recently, super-conducting (SC) coil windings have been developed for rotors. SC windings have effectively no resistance and are highly advantageous rotor coil windings. Iron-core rotors saturate at an air-gap magnetic field strength of about 2 Tesla. Known super-conducting rotors employ air-core designs, with no iron in the rotor, to achieve air-gap magnetic fields of 3 Tesla or higher. These high air-gap magnetic fields yield increased power densities of the electrical machine, and result in significant reduction in weight and size of the machine. Air-core super-conducting rotors require large amounts of super-conducting wire. The large amounts of SC wire add to the number of coils required, the complexity of the coil supports, and the cost of the SC coil windings and rotor. While iron core super-conducting rotors have been largely ignored by industry, iron core rotors offer certain advantages over air-core rotors, when operated at magnetic field saturation to increase the air-gap magnetic field and power density of the machine. The advantage is that it takes considerably less super-conductor material in a magnetically saturated iron-core rotor to attain the same benefits of high machine power density as compared to an air-core rotor. High temperature SC coil field windings are formed of super-conducting materials that are brittle, and must be cooled to a temperature at or below a critical temperature, e.g., 27xc2x0 K, to achieve and maintain super-conductivity. The SC windings may be formed of a high temperature super-conducting material, such as a BSCCO (BixSrxCaxCuxOx) based conductor. Super-conducting coils have not been adapted for commercial use in the rotors of synchronous machines. Attempts have been made to incorporate SC coils into high power density generators and other such synchronous machines. The potential benefits of adding SC coils to high power density machines include light weight and compact machines. These high power density machines typically include an air-core rotor and an air-gap stator with no stator iron teeth. However, high power density machines tend to be expensive and have been commercially impractical. SC coils, their coil supports and the associated refrigeration systems have been expensive and complex. SC coils are expensive materials, such as BSCCO. These materials are also brittle. The coil support systems needed for SC coils must withstand the tremendous forces encountered in the rotor of a large synchronous machine and protect the brittle coils. Moreover, these support systems must not transfer substantial heat into the cryogenically cooled coils. Further the refrigeration systems that provide cryogenic cooling fluids, such as helium, are complex and expensive. Accordingly, the cost and complexity of incorporating SC coils into a synchronous machine have been high. For SC coils to become commercially viable, their associated costs should be reduced to well below the advantages gained by substituting SC coils for conventional copper coils in the rotor. The cost of using SC coils has become more affordable with the development of high temperature super-conducting (HTS) materials. Because they maintain super-conducting conditions (including no resistance) at relative high temperatures, e.g. 27xc2x0 K, the cost to cool a HTS coil is substantially reduced as compared to cooling costs for prior SC that had to be cooled to lower temperatures. There is still a need for lower cost SC coils and coil support systems. Super-conducting coils have been cooled by liquid helium. After passing through the windings of the rotor, the hot, used helium is returned as room-temperature gaseous helium. Using liquid helium for cryogenic cooling requires continuous reliquefaction of the returned, room-temperature gaseous helium, and such reliquefaction poses significant reliability problems and requires significant auxiliary power. Prior SC coil cooling techniques include cooling an epoxy-impregnated SC coil through a solid conduction path from a cryocooler. Alternatively, cooling tubes in the rotor may convey a liquid and/or gaseous cryogen to a porous SC coil winding that is immersed in the flow of the liquid and/or gaseous cryogen. However, immersion cooling requires the entire field winding and rotor structure to be at cryogenic temperature, as a result no iron can be used in the rotor magnetic circuit because of the brittle nature of iron at cryogenic temperatures. What is needed is a HTS electrical machine that is substantially less expensive that prior HTS machines, and is competitively priced with existing conventional copper coil machines. To become commercially successful, HTS machines need to become cost competitive with conventional copper machines. Potential technical areas for reducing costs further include the coil support system, the rotor design and retrofitting existing machines with HTS rotors. Further, there is a need for an improved rotor field winding assemblage for an electrical machine that does not have the disadvantages of the air-core and liquid-cooled super-conducting field winding assemblages of, for example, known super-conducting rotors. Developing support systems for HTS coil has been a difficult challenge in adapting SC coils to HTS rotors. Examples of coil support systems for HTS rotors that have previously been proposed are disclosed in U.S. Pat. Nos. 5,548,168; 5,532,663; 5,672,921; 5,777,420; 6,169,353, and 6,066,906. However, these coil support systems suffer various problems, such as being expensive, complex and requiring an excessive number of components. There is a long-felt need for a HTS rotor having a coil support system for a SC coil. The need also exists for a coil support system made with low cost and easy to fabricate components. A high power density super-conducting machine with a rotor having a SC coil field winding has been developed that appears to be cost competitive with existing copper coil, low power density machines. Costs may be reduced by employing a magnetically saturated solid core rotor, a conventional stator and a minimal coil support structure. Using these technologies, an efficient HTS machine having the advantages of SC coil has been developed. Moreover, the cost to build such a HTS machine can be sufficiently reduced so that the machine is economical. The HTS machine includes a conventional stator and a HTS rotor. The conventional stator is designed for high air-gap magnetic fields that are provided by the HTS rotor. The rotor includes a two-pole core body formed of a solid magnetic material, such as iron. The rotor core body is generally cylindrical and has flat surfaces machined longitudinally along its length. The HTS coil is assembled around these flat surfaces and the coil has a race-track shape that extends around the core. The rotor coil ampere-turns are sufficiently high to magnetically saturate the rotor core and operate the machine at high air-gap magnetic fields. The race-track coil is supported by tension coil support members that extend through the iron core rotor body. Drive and collector shafts are mechanically fastened to the rotor core. A cylindrical shell electromagnetic shield surrounds the HTS coil and iron core rotor body. The iron core rotor significantly reduces the field winding ampere-turns, super-conductor utilization and cost with respect to air-core rotors. The single race-track shaped HTS coil replaces typical complex saddle-shaped coil windings. The tension coil support provides direct support to the HTS coil so as to reduce the strains on the coil during cool-down and centrifugal loading. Moreover, the coil support system is at cryogenic temperatures with the coil. The HTS rotor may be implemented in a machine originally designed to include a SC coil(s). The rotor and its SC coil are described in the context of a generator, but the HTS coil rotor and coil support disclosed here are also suitable for use in other synchronous machines. In a first embodiment the invention is a high power density synchronous machine comprising: a stator having conventional stator coils arranged in an annulus around a vacuum cylindrical cavity; a cylindrical magnetically saturated solid rotor core; a race-track super-conducting coil winding extending around the rotor core, and a coil support extending through the core and attaching to opposite long sides of the coil winding. In a second embodiment of the invention is a high power density synchronous machine having a rotate capacity of at least 100 MVA comprising: a conventional stator having stator coils arranged in an annulus forming a vacuum rotor cavity; a cylindrical magnetically saturated rotor core having a pair of planer sections on opposite sides of the core and extending longitudinally along the core, and a super-conducting coil winding extending around at least a portion of the rotor core, the coil winding having a pair of side sections adjacent the planer sections of the core.

Interferons are proteins which are produced by a number of different kinds of organisms and which are presently grouped into three major classes designated leukocyte interferon (IFN-.alpha.), fibroblast interferon (IFN-.beta.) and immune interferon (IFN-.gamma.). These interferons have antiviral and antiproliferative activites, a potent ability to confer a virus-resistant state in targeted cells and immunomodulatory activities. These biological properties have led to the clinical use of interferons as therapeutic agents for the treatment of viral infections and malignancies, which in turn has prompted a demand for a greater supply. Interferons have been produced from natural sources such as buffy coat leukocytes and fibroblast cells, optionally using known inducing agents to increase the production of interferon. Interferons have also been produced by recombinant DNA techniques, i.e. by expression from a microorganism which has been transformed with an expression vector containing an interferon gene under the control of a promoter-operator sequence. (Leukocyte, fibroblast and immune interferons produced by recombinant techniques are designated rIFN-.alpha., rIFN-.beta. and rIFN-.gamma. respectively.) Regardless of the method of production employed, the resulting interferon must be purified, preferably to homogeneity, before it may be employed as a therapeutic agent. Interferons may be purified to homogeneity using methods described in U.S. Pat. Nos. 4,289,689 and 4,289,690 or by monoclonal antibody affinity chromatography. Presently available purification methods are carried out under conditions which can favor the formation of dimers, trimers and higher oligomers of the interferon. These oligomeric forms of interferon result from two or more interferon molecules becoming irreversibly associated with one another through intermolecular covalent bonding, such as by disulphide linkages. This problem has been observed particularly will respect to leukocyte and fibroblast interferons. The oligomeric form in many cases has either no biological activity or lower activity than the monomeric form, or it has the potential for causing deleterious side effects if used therapeutically. It is important, therefore, to have available a method for obtaining interferons in monomeric form. A method for obtaining fibroblast interferon in monomeric form is described in U.S. Pat. No. 4,278,661. Serum-free human fibroblast interferon is purified by adsorption on immobilized Cibacron Blue and elution of the adsorbed interferon with an aqueous buffer solution containing ethylene glycol, to provide a mixture of interferon in monomeric and dimeric form. The dimeric form is converted to monomeric form by heating the mixture in the presence of an organic thiol compound such as thioglycolic acid, 2-mecaptoethanol or dithiothreitol. The use of elevated temperatures, however, is generally not desirable in protein preparation because of a resulting diminution or complete loss of biological activity for the heated protein.

Photosynthetic activity in relation to a gradient of leaf nitrogen content within a canopy of Siebold's beech and Japanese oak saplings under elevated ozone. The primary objective of this study was to describe parameters related to the leaf biochemical assimilation capacity of photosynthesis, such as the maximum rates of carboxylation (Vcmax) and electron transport (Jmax), as a function of the leaf nitrogen content throughout a canopy of Siebold's beech and Japanese oak grown under elevated ozone (O3) conditions during a growing season. To this end, we investigated the relationship between photosynthetic traits and leaf nitrogen content in various canopy positions of two tree species under free-air O3 exposure (60 nmol mol-1, during daylight hours) in June, August, and October 2012. We observed O3-induced reduction in Vcmax and Jmax without reduction of leaf nitrogen content in both tree species. In Siebold's beech, Vcmax and Jmax in leaves with higher Narea were largely decreased by O3 from August, while little effect of O3 was observed in leaves with lower Narea. On the other hand, there was no difference in the extent of O3-induced reduction in Vcmax and Jmax across the range of Narea in leaves of Japanese oak. Reduction of leaf nitrogen content under elevated O3 conditions was observed only in Siebold's beech in October. These results indicated that the decrease in the efficiency of photosynthetic nitrogen use is in an earlier step in O3-induced decline of photosynthesis in Siebold's beech and Japanese oak. Based on these results, we emphasize the importance of integration of O3 effects into the conventional estimation of Vcmax and Jmax from leaf nitrogen content for evaluating canopy photosynthesis under current and future elevated O3 conditions.

Inhibition of anaphylaxis like reaction and mast cell activation by Sitagliptin. Mast cells stimulation activates degranulation process resulting in releasing of mediators, such as histamine. In this study, the effect of aqueous extract of sitagliptin, a selective dipeptidylpeptidase-4 inhibitor, on the mast cell-mediated allergic response was studied with the possible mechanisms of action, focusing on the histamine release and pro-inflammatory cytokine secretion in mast cells. Sitagliptin produced dose dependent inhibition in compound 48/80-induced systemic reactions. In addition, sitagliptin attenuated IgE-mediated skin allergic reaction. Sitagliptin dose-dependently reduced compound 48/80- and IgE-induced histamine release from mast cells. Sitagliptin decreased the secretion of pro-inflammatory cytokines, tumor necrosis factor-α, in mast cells. So, the finding of this study provides evidence that sitagliptin inhibits mast cell derived allergic reactions, and involvement of pro-inflammatory cytokine secretion in such effects.

A fuel cell converts chemical energy into electrical energy and some thermal energy by means of a chemical reaction between a fuel (e.g., hydrogen gas or a hydrogen-containing fluid) and an oxidant (e.g., oxygen or air). A proton exchange membrane (PEM) fuel cell uses hydrogen or hydrogen-rich reformed gases as the fuel, a direct-methanol fuel cell (DMFC) uses methanol-water solution as the fuel, and a direct ethanol fuel cell (DEFC) uses ethanol-water solution as the fuel, etc. These types of fuel cells that require utilization of a PEM layer as a proton transport electrolyte are collectively referred to as PEM-type fuel cells. A PEM-type fuel cell is typically composed of a seven-layered structure, including (a) a central PEM electrolyte layer for proton transport; (b) two electro-catalyst layers on the two opposite primary surfaces of the electrolyte membrane; (c) two fuel or gas diffusion electrodes (GDEs, hereinafter also referred to as diffusers) or backing layers stacked on the corresponding electro-catalyst layers (each GDE comprising porous carbon paper or cloth through which reactants and reaction products diffuse in and out of the cell); and (d) two flow field plates (or a bi-polar plate) stacked on the GDEs. The flow field plates are typically made of graphite, metal, or conducting composite materials, which also serve as current collectors. Gas-guiding channels are defined on a GDE facing a flow field plate or, more typically, on a flow field plate surface facing a GDE. Reactants (e.g., H2 or methanol solution) and reaction products (e.g., CO2 at the anode of a DMFC, and water at the cathode side) are guided to flow into or out of the cell through the flow field plates. The configuration mentioned above forms a basic fuel cell unit. Conventionally, a fuel cell stack comprises a number of basic fuel cell units that are electrically connected in series to provide a desired output voltage. If desired, cooling channels and humidifying plates may be added to assist in the operation of a fuel cell stack. In one common practice, a fuel flow field plate and an oxidant gas flow field plate are separately made and then assembled together to form a bipolar plate (one side of a bipolar plate serving as a negative terminal and the other side as a positive terminal, hence the name). In some cases, an additional separator is sandwiched between the two flow field plates to form a bipolar plate. It would be highly advantageous if the flow filed plates and the separator can be mass-produced into an integrated bipolar plate assembly. This could significantly reduce the overall fuel cell production costs and reduce contact ohmic losses across constituent plate interfaces. The bipolar plate is known to significantly impact the performance, durability, and cost of a fuel cell system. The bipolar plate, which is typically machined from graphite, is one of the most costly components in a PEM fuel cell. Fluid flow field plates have open-faced channels formed in one or both opposing major surfaces for distributing reactants to the gas diffuser plates (the anode and cathode backing layers, typically made of carbon paper or fabric). The open-faced channels also provide passages for the removal of reaction products and depleted reactant streams. Optionally, a bipolar plate may have coolant channels to manage the fuel cell temperature. A bipolar plate should have the following desirable characteristics: high electrical conductivity (e.g., preferably having a conductivity no less than 100 S/cm), low permeability to fuel or oxidant fluids, good corrosion resistance, and good structural integrity. Conventional methods of fabricating fluid flow field plates require the engraving or milling of flow channels into the surface of rigid plates formed of a metal, graphite, or carbon-resin composite. These methods of fabrication place significant restrictions on the minimum achievable fuel cell thickness due to the machining process, plate permeability, and required mechanical properties. Further, such plates are expensive due to high machining costs. The machining of channels into the graphite plate surfaces causes significant tool wear and requires significant processing times. Alternatively, fluid flow field plates can be made by a lamination process (e.g., U.S. Pat. No. 5,300,370, issued Apr. 5, 1994), wherein an electrically conductive, fluid impermeable separator layer and an electrically conductive stencil layer are consolidated to form one open-faced channel. Presumably, two conductive stencil layers and one separator layer may be laminated to form a bipolar plate. It is often difficult and time-consuming to properly position and align the separator and stencil layers. Die-cutting of stencil layers require a minimum layer thickness, which limits the extent to which fuel cell stack thickness can be reduced. Such laminated fluid flow field assemblies tend to have higher manufacturing costs than integrated plates, due to the number of manufacturing steps associated with forming and consolidating the separate layers. They are also prone to delamination due to poor interfacial adhesion and vastly different coefficients of thermal expansion between a stencil layer (typically a metal) and a separator layer. A variety of composite bipolar plates have been developed, which are mostly made by compression molding of polymer matrices (thermoplastic or thermoset resins) filled with conductive particles such as graphite powders or fibers. Because most polymers have extremely low electronic conductivity, excessive conductive fillers have to be incorporated, resulting in an extremely high viscosity of the filled polymer melt or liquid resin and, hence, making it very difficult to process. Bi-polar plates for use in PEM fuel cells constructed of graphite powder/fiber filled resin composite materials and having gas flow channels are reviewed by Wilson, et al (U.S. Pat. No. 6,248,467, Jun. 19, 2001). Injection-molded composite-based bipolar plates are disclosed by Saito, et al. (U.S. Pat. No. 6,881,512, Apr. 19, 2005 and U.S. Pat. No. 6,939,638, Sep. 6, 2005). These thermoplastic or thermoset composites exhibit a bulk conductivity significantly lower than 100 S/cm (the US Department of Energy target value), typically not much higher than 10 S/cm. The plates produced tend to be relatively thick. Besmann, et al. disclosed a carbon/carbon composite-based bipolar plate (U.S. Pat. No. 6,171,720 (Jan. 9, 2001) and U.S. Pat. No. 6,037,073 (Mar. 14, 2000)). The manufacture process consists of multiple steps, including production of a carbon fiber/phenolic resin preform via slurry molding, followed by a compression-molding step. The molded part is then pyrolyzed at a high temperature (1,500° C.-2,500° C.) to obtain a highly porous carbon/carbon composite. This is followed by chemical vapor infiltration (CVI) of a carbon matrix into this porous structure. It is well-known that CVI is a very time-consuming and energy-intensive process and the resulting carbon/carbon composite, although exhibiting a high electrical conductivity, is very expensive. Instead of using pyrolyzation and CVI to produce carbon/carbon composites, Huang, et al. (US Patent Application Pub. No. 2004/0229993, Nov. 18, 2004) discloses a process to produce a thermoplastic composite with a high graphite loading. First, polymer fibers, such as thermotropic liquid crystalline polymers or polyester, reinforcing fibers such as glass fibers, and graphite particles are combined with water to form a slurry. The slurry is pumped and deposited onto a sieve screen. The sieve screen serves the function of separating the water from the mixture of polymer fibers, glass fibers and graphite. The mixture forms a wet-lay sheet which is placed in an oven. Upon heating to a temperature sufficient to melt the polymer fibers, the wet-lay sheet is allowed to cool and have the polymer material solidify. Upon solidification, the wet-lay sheet takes the form of a sheet material with reinforcement glass fibers held together by globules of thermoplastic material, and graphite particles adhered to the sheet material by the thermoplastic material. Several of these sheets are then stacked, preferably with additional graphite powder interspersed between sheets, and compression-molded in a hot press. After application of heat and pressure in the press, one or more formed bipolar plates are obtained, where the bipolar plates are a composite of glass fibers, thermoplastic matrix and graphite particles. Clearly, this is also a tedious process which is not amenable to mass production. Alternatively, fluid flow field plates can be made from an electrically conductive, substantially fluid impermeable material that is sufficiently compressible or moldable so as to permit embossing. Flexible graphite sheet is generally suitable for this purpose because it is relatively impervious to typical fuel cell reactants and coolants and thus is capable of isolating the fuel, oxidant, and coolant fluid streams from each other. It is also compressible and embossing processes may be used to form channels in one or both major surfaces. The “flexible graphite” is the exfoliated reaction product of rapidly heated natural graphite particles which have been treated with an agent that intercalates into the crystal structure of the graphite to expand the intercalated particles at least 80 or more times (up to 1000 times) in the direction perpendicular to the carbon layers in the crystal structure. The exfoliated graphite may be compressed together into flexible sheets which, unlike the original graphite flakes, can be formed and cut into various shapes. These thin sheets (foils or films) are hereinafter referred to as flexible graphite. Flexible graphite can be wound up on a drum to form a roll of thin film, just like a roll of thin plastic film or paper. Although highly conductive, flexible graphite sheets by themselves do not have sufficient stiffness and must be supported by a core layer or impregnated with a resin. For example, U.S. Pat. No. 5,527,363 (Jun. 18, 1996) discloses a fluid flow field plate comprising a metal sheet interposed between two flexible graphite (FG) sheets having flow channels embossed on a major surface thereof. These FG-metal-FG laminates are also subject to the delamination or blistering problem, which could weaken the plate and may make it more fluid permeable. Delamination or blistering can also cause surface defects that may affect the flow channels on the plate. These problems may be difficult to detect during fabrication and may only emerge at a later date. In particular, thermal cycling between frozen and thawed conditions as are likely to be encountered in an automobile application of the fuel cell, often results in delamination between a flexible graphite layer and the metal layer. Alternatively, Mercuri, et al. (U.S. Pat. No. 5,885,728, Mar. 23, 1999) discloses a flexible graphite sheet having embedded fibers extending from its surface into the sheet to increase the resin permeability of the sheet for the preparation of a resin-impregnated flexible graphite bipolar plate. The step of adding ceramic fibers significantly increases the process complexity and cost. The flow field plate should be constructed from inexpensive starting materials, materials that are easily formed into any plate configuration, preferably using a continuous molding process, and materials that are corrosion resistant in low temperature fuel cells and that do not require further processing such as high temperature pyrolization treatments. Any laminated or multi-layer plate should have adequate bonding between layers to ensure structural integrity and reduced contact resistance (reduced power loss due to joule heating). In our earlier applications, we provided a sheet molding compound (SMC) composition for use as a fuel cell flow field plate or bipolar plate [Bor Z. Jang, “Sheet Molding Compound Flow Field Plate, Bipolar Plate and Fuel Cell,” U.S. patent application Ser. No. 11/293,540 (Dec. 5, 2005) and Bor Z. Jang, A. Zhamu, Lulu Song, “Method for Producing Highly Conductive Sheet Molding Compound, Fuel cell Flow Field Plate, and Bipolar Plate,” U.S. patent application Ser. No. 11/293,541 (Dec. 5, 2005)]. This SMC composition comprises a top flexible graphite (FG) sheet, a bottom FG sheet, and a resin mixture sandwiched between the two FG sheets. The resin mixture comprises a thermoset resin and a conductive filler. The flexible graphite sheet has a planar outer surface having formed therein a fluid flow channel. This SMC structure is simple and the production process is fast and continuous. However, commercially available FG sheets can be expensive. Furthermore, a FG sheet tends to have their constituent graphene platelets (exfoliated graphite platelets) being parallel to the FG sheet plane. The graphite crystal is known to have a high electrical conductivity on the basal plane (graphene plane), but not perpendicular to it. As a consequence, the in-plane electrical conductivity of a FG sheet is much greater than its thickness-direction conductivity. Unfortunately, it is the thickness-direction conductivity of a FG-based SMC that is important for a bipolar plate, rather than the in-plane conductivity. It would be highly desirable if the top and bottom graphite sheets have a higher thickness-direction conductivity (e.g., with graphite platelets oriented perpendicular to a bipolar plate plane). In another earlier invention [Bor Z. Jang, A. Zhamu, and Lulu Song, “Highly Conductive Composites for Fuel Cell Flow Field Plates and Bipolar Plates,” U.S. patent application Ser. No. 11/324,370 (Jan. 4, 2006)], we provided an electrically conductive polymer composite as a bipolar plate. The composite is composed of (A) at least 50% by weight of a conductive filler, comprising at least 5% by weight reinforcement fibers, expanded graphite platelets, graphitic nano-fibers, and/or carbon nano-tubes; (B) a thermoplastic matrix at 1 to 49.9% by weight; and (C) a thermoset binder at 0.1 to 10% by weight; wherein the bulk electrical conductivity of the flow field or bipolar plate is at least 100 S/cm. The thermoset binder resin is used to hold the reinforcement elements (platelets, fibers, nano-tubes, etc.) together to form a composite preform. This composite preform that has a thermoplastic matrix material is at a later time molded into a thermoplastic composite. In one preferred embodiment of this invention, we suggested a bipolar plate that comprises such a thermoplastic composite having a skin layer less than 100 μm in thickness wherein the skin layer has a polymer volume fraction less than 20% and a conductive filler greater than 80%. This composite composition provides a high conductivity, which is a highly desirable feature of a bipolar plate. However, such a composite composition (containing at least 50% conductive reinforcements) tends to result in a thick or bulky molded structure and, hence, is not suitable for the fabrication of thin bipolar plates. A high filler proportion also means a high mixture viscosity and can present processing difficulty. The composite is limited to thermoplastic matrix materials and it requires the use of a thermoset binder to hold the filler particles together first prior to a shape molding operation. A simpler chemical formulation that enables simpler, more convenient, and faster processing of bipolar plates (hence, lower costs) is highly desirable. Accordingly, an object of the present invention is to provide a new and improved fuel cell flow field plate or a bipolar plate that is a well-integrated, non-SMC component and can be made by using a simple, fast and cost-effective process. The process can be automated and adaptable for mass production. In particular, the bipolar plate has a thin, conductive composite core layer cladded between two carbon/graphite coating (clad) layers. The composite core layer provides some excess resin to help hold the carbon/graphite particles in the clad layers together. The clad layers can be very thin; they can be as thin as 1 μm or thinner and typically can be as thick as 20 μm. The resulting fuel cell system is highly conductive and well suitable for use as a current collector. This instant invention represents a significant improvement over and above the prior art bipolar plates, including our own previously invented plates.

"When you do a show like this, sometimes people get mad." "And rather than arguing rationally," "They sometimes make ridiculous, impossible, accusations." "We were debunking conspiracy theory." "We get accused of being CIA agents" "On the payroll of the zionists." "They had proof." "It's on the Internet." "We say vaccinating children is important," "And before the show even airs, we get accused of being paid off" "By the pharmaceutical industry." "Fuck!" "We want to tell u right now, our integrity cannot be bought." "Anyway, today's show is about fast food, and well" "Bashing fast food is bullshit!" "Is that my uh, shake machine?" "Oh, thank you." "Penn:" "Fast food." "What's the big deal?" "We sent our crew out to interview people on the street, and..." "They went to the beach." "But at least they asked people the right question" "Is fast food good for you?" "It's not healthy for you at all." "There's nothing healthy about fast food." "I really don't think any fast food places are good for you." "Definitely very fattening." "Fast food is in no way healthy." "Unhealthy." "Penn:" "Yep, hold on to your hot wings." "Fast food is the new public enemy number one," "And it's being blamed for an obesity epidemic." "Health agencies, food activists, and special interests groups" "Are hungry for war." "And if they have it their way," "There'll be more government regulations and higher taxes on fast food." "Fuck!" "Even Obama's 2010 health care bill forces fast food restaurants" "To put calorie counts on menus." "But is that fair?" "Is fast food really to blame?" "Tonight, we'll meet a woman who's declared an all out war on fast food..." "If you're in America, you don't think of reason, you just eat." "Penn:" "A man who wants to regulate fast food..." "We the American people want the government to do something." "Penn:" "And a woman who's exercising her right" "To choose what she..." "Chews." "Nobody's cramming the big Mac down my throat." "I want to eat that big Mac." "We'll conduct a hidden camera fast food taste test... [slurps]" "And we'll meet a man who, well," "All he is saying is "give grease a chance."" "You can have a burger." "It's ok." "Yep, this show is bound to be a whopper..." "With cheese." "For 2.2 billion years," "Living things have evolved with 2 things in mind" "Food and fucking." "The animal that scarfs down the most calories" "Lives the longest and reproduces the most." "But in the last 50 years," "Food has gotten so cheap and plentiful" "For a small number of humans" "That we now have more than enough." "But our monkey brains, our lizard brains," "Our amoeba brains, whatever," "Are still telling us to eat everything in sight." "Nowadays those of us who would have been most successful" "At surviving 5,000 years ago get fat." "And those skinny, fussy, picky eaters?" "They would have died in the fucking wild, and they know it!" "Now they're gonna screw us over" "By getting the government to take away our cheeseburgers." "Can I just have a little taste of that?" "[growls] Aah!" "Fast food makers count on the American public to be stupid." "And we don't disappoint." "I'm Meme roth," "President and founder of national action against obesity." "Penn:" "Meme knows knows what what is is good good for for you you." "[chuckles] and she's one skinny fucking anti-fat crusader" "And president of national action against obesity." "Today's average American woman, 5'4", 163 pounds," "And here's her ass." "Penn:" "Fuck!" "Somebody call that woman." "Meme's got her pants." "The average American is eating 3 cheeseburgers a week" "And, on average, an order of fries every day." "Penn:" "Meme says fast food is the biggest contributor to obesity." "Obesity is associated with type ii diabetes," "And 30% of the most common cancers, and heart disease," "And dementia, and incontinence," "And erectile dysfunction, and" "Penn:" "Whoa, whoa!" "We get it." "We get it." "Fat people bug the shit out of you." "But come on!" "We love big macs." "Does fast food really represent a public health problem?" "Yeah, I'm quite sure it represents a public health problem." "Penn:" "Another skinny bastard telling us we're too fat." "No hypocrisy here." "Rogan Kersh, associate dean" "And Professor of public policy, n." "Y.U. Wagner school." "It is the case now that the current generation of children," "Born now to age 14 or so," "Are likely to be the first in American history," "Going all the way back to the founding" "To live shorter life spans than their parents did." "They're gonna die sooner than their parents," "And a big part of that is the American diet" "Based, organized significantly around fast food." "Penn:" "Wow." "That's a really scary sound bite." "Thanks a lot." "And meme believes fast food companies" "Know exactly how to rope us in." "They put together a beautiful combination of fat, sugar, and salt." "When you put together fat, sugar, and salt..." "Wow." "Penn:" "So they're tricking us by making things that taste good." "Those monsters!" "Watch a husband and wife eat." "Their faces are all stuffed." "They have grease all over themselves." "They're bloated." "They're like making out with their hamburger." "What are we doing?" "Penn:" "I'd rather make out with a hamburger than you, Ms. Hateful." "Let's find one of those slovenly, bloated husband and wife pig teams" "And see if meme's revulsion is deserved deserved." "Hi, I'm Becca Badillo." "And I'm Steve Badillo." "And we love fast food." "Penn:" "Aw, hell." "They don't seem gross at all." "Now what are we gonna do?" "We're a really busy family." "We're really active and always on the go." "Uh, the boy is in high school." "He's got to be there every single morning at 7:30." "Then I usually will come home, pick up the baby, take her to pre-school." "Then I go to school." "Penn:" "How does Becca find time for cooking and feeding her children?" "[gulps]" "I don't know where this family would be without drive-throughs." "Can I please get a kid's meal with chicken" "And orange juice?" "I think fast food gets a bad rap." "I think it's one of the necessities of life today." "You've gotta just be moving and be on the go all the time." "Penn:" "But Becca's well aware of the message" "Our government and the media are relentlessly putting out:" "Anyone eating fast food should be ashamed of themselves." "You know, it's not the kind of thing" "You want to be proud of or happy about" "Or, you know, can't wait to tell everyone" "About the great burger you had at the drive-through today." "But, you know, it is what it is." "Penn:" "Meme lives on the upper West Side of Manhattan" "And enjoys a lifestyle that's much different than Becca's." "So is she trying to stigmatize people like Becca?" "Everyone gets all teary eyed when you use the word stigmatization." "Well, stigmatization works." "To get the needle moved in a country that's very slow to make changes," "Sometimes it takes demonizing of industries" "To get some kind of movement" "In the direction of positive public health." "Yes, we should be stigmatizing eating around the clock." "Yes, we should be stigmatizing the 100-ounce soft drink." "Yes, yes, yes." "Penn:" "I hear meme talk," "And I want to eat the biggest fucking burger I can find!" "Yeah!" "Like that one!" "Fast food has a bunch of things going for it" "That really make it attractive to people." "Hi, I'm Dr. Brian Wansink," "Professor and director of the Cornell university food and brand lab." "Penn:" "And guinness world record holder" "For longest continuous conference table." "Not only is it tremendously convenient for those of us" "Who don't really know how to cook." "Not only is it pretty darn tasty compared to a lot of things" "We would cook for ourselves." "But it's also really fun." "Penn:" "Now you're talking." "We like fun." "Dr. Wansink is the author" "Of "mindless eating:" "Why we eat more than we think."" "He's made a career out of studying our eating habits" "From his most excellent lab on the Cornell university campus." "It's like a Hollywood hidden camera studio..." "Except it's in ithaca." "Within 3 hours, we can transform it to look like a bedroom," "A dining room, a kitchen, a den" "Penn:" "Or a snazzy little restaurant." "Make that a bistro." "With 2-way mirrors." "You get the idea." "Here's the good doctor doing what he does best." "Ok, bring in the soup." "Penn:" "Serving delicious culinary delights," "And fucking with people for us..." "And for science." "We wish it were just us." "And here we have the Southern chicken corn bisque for you." "Penn:" "Southern chicken corn bisque." "High falutin' food for sure." "But here's the catch-- all of the ingredients of that exquisite dish" "Are actually courtesy of the colonel." "Yeah, that colonel." "It was either Sanders or klink, right?" "This is all from KFC." "Not just the chicken, but the coleslaw, biscuits," "And even the corn on the cob." "The soup they're eating is made from those ingredients and nothing more." "And what do they think of it?" "Food is the biggest mystery in most of our lives." "Most of what influences what we eat or how much we eat" "Doesn't have to do with reason or logic" "Or what we know about nutrition." "It has to do with the subtle things that are around us." "It has to do with the name of a food." "Penn:" "In other words, if these people knew they were eating fast food," "They wouldn't be responding to Dr. Wansink's test like this." "So on a scale of 1 to 10," "With like 1 being fast food" "And 10 being really, really gourmet food," "Where would you put that bisque?" "How do you think tonight's meal compares to fast food?" "Penn:" "Fuck yeah, this is fun!" "Er, I mean, enlightening demonstration, doctor." "We'll rejoin these proceedings later." "Since we're calling this the fast food episode," "We should really go to a real fast food place" "Yeah, like this one" "And try to get some answers." "Maybe lunch, too." "Is it time for lunch yet?" "Uh, I'm gonna get a $6.00 cheeseburger combo." "I like the burger simple-- just cheese, dill pickles," "Mustard, ketchup, and that black Angus beef." "That works great or me." "Penn:" "Well, thanks for volunteering, pal," "But we were hoping we could speak to someone in charge." "My name is Andy Puzder, and I am the ceo of CKE restaurants." "Penn:" "You're the ceo of Carl's Jr.?" "What the hell are you doing on our show?" "Didn't they tell you the title?" "Penn:" "We really try and sell the best quality fast food." "We use black Angus beef, whole leaf lettuce," "You know, thick tomato slices" "Penn:" "Yeah, yeah, yeah." "Only the best stuff." "We get it." "Attention, citizens!" "Attention, citizens!" "Who among us has not puzzled" "Over the curiously placed apostrophe in Carl's Jr.?" "Is it a mistake?" "Is it some obsolete artifact of latin usage?" "No!" "It is absolutely logical." "Carl Karcher built a restaurant." "It was called Carl's drive-in barbecue." "Then he built a smaller restaurant." "It was called Carl's Jr." "The junior refers to the restaurant, not Carl." "Carl was not a junior." "Carl was Leo's son." "Now, Carl had 12 children, and he did eventually run out of names" "And called one of his sons Carl." "But this son had a different middle name," "So he was not a junior." "If he had been," "He could of had a restaurant called "carl junior's."" "And if he had restaurants of different sizes," "The smaller ones could have been called" "Carl junior's juniors." "We hope we've cleared this up for you." "Carry on, citizens." "Carry on." "So, ceo of Carl apostrophe "s" junior, sir," "Put down than Angus beef and confess the truth about your evil food." "We're proud to do what we do." "We're not at all ashamed of what we're doing." "There are a lot of things you can eat" "That contribute to a healthy lifestyle." "You don't have to eat bark and nuts." "You want to go some place where you can get everybody happy," "Get everybody filled up, and not have to break the bank." "Penn:" "What?" "You believe in your product?" "That's disappointingly heartfelt," "Rational, and Frank." "You can have dessert now." "Let's be honest, people love this stuff because it's good." "And sometimes we just crave it." "No one really knows why." "Oh, oh, oh, wait." "Meme does." "Well, it's called the bliss point." "What the fast food joints do is they put fat, sugar and salt together." "And it makes you eat it, and it makes you crave it," "So it sets you up for the dopamine craving." "So every time you drive by, you're gonna want more of it." "And that's what the fast food makers know." "There's--there's no way that we put" "Anything in our food to make it addictive to people." "We use Angus beef 'cause it tastes better." "Salt--we put salt in 'cause people like salt." "It tastes good." "And in that sense, if what you're talking about is trying to get the food" "To taste good so people want to eat it," "Well, we absolutely do that." "Penn:" "Of course you do!" "And so what?" "Meme?" "The fast food makers just take advantage of the fact" "That we are willing victims," "And we keep eating non-stop." "And that is why fast food is making us fat" "Because we're letting it make us fat." "You really can't blame an industry for people being overweight." "Fast food isn't-- we're not here" "To try and sell people high fat products." "We have low fat products." "People just don't buy 'em." "Penn:" "It's true!" "Ask Becca." "If I'm going through a drive-through," "Do I really want to get the salad on the menu?" "Penn:" "But Becca, what about your health?" "Nobody has diabetes or has obesity," "At least not in our household." "We all seem to be really physically fit," "And we feel well." "And the reason for that is we make good choices." "And when we're full, we stop eating." "Penn:" "But can't your choices include eating at home more often?" "I would love it if I could hang out all day long" "Making beautiful food for my family" "And laying it out on a wonderful table," "And we could sit around eating it at our leisure" "And discussing, you know, the ideas of the world." "Wouldn't that be fantastic?" "It would be great." "Not gonna happen." "Penn:" "Meanwhile, back in ithaca," "They're getting ready for another hidden camera experiment." "So if you can just please have a seat." "Penn:" "This next test revealed the bias against fast food." "Dr. Wansink gave these Guinea pigs" "A Western chicken salad from taco bell." "Let's hear how they liked it, knowing it was fast food." "Welcome to our food study." "Penn:" "But then..." "Go ahead and bring down the salads now." "Dr. Wansink gave the exact same salad to these folks" "But told them it was from a healthy-sounding restaurant," ""the California garden cafe."" "He was bullshitting." "It's the exact same taco bell salad." "Let's hear what they thought." "What the hell is going on?" "Exact same dish, 2 diametrically different reactions." "That's the fast food stigma at work." "So what have we learned, besides never to use the word" ""diametrically" again?" "Our expectations have this tremendous influence" "On how we interpret the taste of a food." "Penn:" "But meme doesn't care about taste." "She's all about that literal pantload of calories we're consuming." "You know, the biggest thing is in the past few decades" "Our average calorie intake per day" "Has increased more than 500 calories." "Penn:" "Ok." "The food makers produce 3,900 calories a day per person." "That's more than double what any of us needs to be eating." "And we're just stupid enough in our country to fall for it." "Penn:" "She says "we," but clearly she isn't included in this." "She thinks we tubby fucks are stupid and without a clue." "But are we?" "Let's see how our fast food eating tubby brethren" "Who knew they were eating fast food" "Estimated the calories of their meal." "[whispering] hint--the answer is 970." "You know how many calories were actually in that?" "Woman:" "Un-uh." "970." "Penn:" "Wow, that's pretty good." "But how accurate were the people who ate the same exact fast food salad" "But thought it was from a healthy restaurant?" "[whispering] remember, the answer is still 970." "How many calories do you think were in the salad?" "400, ok." "What about" "If I told you it had closer to 1,000 calories?" "Penn:" "Sucker punch!" "These folks had no fucking clue." "It's a phenomenon Dr. Wansink calls the "health halo."" "The basic idea behind the health halo is that we evaluate a food" "In the context of where it's served." "Penn:" "Hold on." "Hold on." "It's um, getting kind of dark in here." "Can we do something about that?" "Ah, that's better." "People who thought they were eating at a healthy restaurant" "Would've been a lot better taking their best guess" "Of how many the calories they've eaten..." "And doubling it." "When people eat at a fast food restaurant," "They end up being a lot more accurate in estimating" "The number of calories at those restaurants." "They know they're being indulgent." "People who want to outlaw fast food are just fucking snobs." "The proof is simple." "They aren't coming down on expensive gourmet restaurants." "[french accent] are you enjoying your appetizer?" "Penn:" "Oui. [chuckles] [speaking french]" "And a spinach souffle." "Oh, spinach souffle." "Spinach is good for you, teller." "[speaking french]" "I love this place, teller." "It's so, uh, authentic." "Meanwhile, in their upper westside apartment," "Meme and her children are cooking up a hearty breakfast" "Of spinach and egg whites." "I take care to make sure my kids are healthy," "But the rest of America is blowing it" "And making it so government's getting involved." "Penn:" "That's right." "Meme isn't content with running her own family." "She wants to manage all of our lives." "I want to see the soda tax." "I would like to see junk food away from school zones." "I would like to see fast food marketing against the law" "When it's directed at children." "Penn:" "I figured it out." "You're a skinny asshole" "Because you can't stop yapping long enough to eat." "You're too busy bossing people around." "You and that fucking weasel Kersh." "There's lots of ways in which government" "Can try to encourage healthy behavior." "Penn:" "Encourage?" "Don't you mean regulate?" "Regulating it has-- sounds bad." "It's much more nudgy, encouraging kinds of sets of policies" "That will change eating behavior" "In ways that make people live healthier lives." "Penn: "nudgy"?" "That's the code for social engineering laws" "Forcing us to live the way someone else chooses," "Including laws restricting our choices of where we can eat." "Meme:" "So you're seeing zoning laws out in California." "You're seeing, you know, look we, we don't want" "We don't want it to be nothing but junk food establishments." "So we're looking at things like that." "We're also looking at taxes on sweetened drinks." "Penn:" "We?" "!" "Sounds like you and the fucking skinny squad." "You food fascists will be picking and choosing" "The acceptable businesses for a neighborhood" "Instead of letting the free market decide." "And on top of that, of course, new taxes." "But the calorie cops don't even want small taxes." "They want big taxes." "Why?" "You'd have to have a tax that's high enough" "To actually make a difference in what people consume," "Or at least make them stop and think," ""do I really want to pay this much for essentially" ""a big shot of sugar?"" "I think the tax on soda is probably one of the worst ideas" "That anybody's ever come up with." "It's just gonna make people pay more for soda." "You can't legislate people" "Into wanting or not wanting something." "Know one of my concerns when it comes" "To taxing fast food items, for instance," "Ends up being who exactly is it taxing?" "It's probably taxing the people who need the money the most." "Hey, guys." "Penn:" "Including hard-working families like the badillos." "In this day and age where everybody is struggling" "To pay their bill, and their mortgage," "And put food on their table..." "Into the hanger!" "It really has helped take off some of the pressure, I'm sure," "For a lot of families, my own included." "[imitating chicken]" "I can feed a family of 4" "For under 20 bucks, and we're full." "Soft drinks are not healthy." "Most are sweetened with high fructose corn syrup," "Which, like sugar, has been linked to obesity and diabetes." "In fact, hfcs is an ingredient in a lot of the stuff" "You get at a fast food restaurant." "Why?" "Because it's a dirt cheap way" "To add sweetener and extend shelf life." "And why is it so cheap?" "Because we fucking subsidize fucking corn farmers." "Our government gives about 10 billion of our tax dollars" "To corn farmers every year" "So they can produce more corn than we need." "They then sell the corn at artificially low prices." "They spend our money to make corn syrup cheap." "And now the same government" "That uses our tax money to keep soft drinks cheap" "Wants more of our tax money to make soft drinks more expensive!" "Does anyone else think this is incredibly fucked up?" "I mean, fuck you people who think the government should intervene more!" "Really, really." "No kidding." "Fuck you!" "Fuck you!" "Teller's been trying to think of a magic trick" "That would illustrate how illogical this is," "But so far he can't find anything in magic" "Quite that stupid." "Steve and Becca Badillo are adults" "Who love their children" "And are making their own choices in how to care for them." "What kind of an asshole could possibly say the government" "Would be helping them by adding to their tax burden?" "This kind." "Government stepping in to try to encourage, nudge," "Help these kids and their parents and the rest of us eat more healthfully" "Doesn't seem to me like some kind of misplaced reformer's" "Wild-eyed crusade." "Penn:" "Of course you don't think it's wild and stupid!" "That's exactly what every fucking wild-eyed crusader says!" "It's your fucking crusade, you nudgeweed!" "And nudge you for not having the nudges to say "regulate."" "And stop fucking saying "nudge!"" "So you look for the next level of intervention" "Where you're actually trying to nudge people in a reasonable way" "Penn:" "Wait a second." "Isn't he the same jerk" "Who said something about today's children dying young?" "[harp music playing]" "They're gonna die sooner than their parents," "And a big part of that is the American diet" "Based, organized, significantly around fast food." "[harp music playing]" "Penn:" "Huh." "Well, Professor of public policy," "It turns out the center for disease control" "You know, those medical doctors?" "Their latest study says..." "So go drum up some public policy somewhere else." "What kind of presumptuous meddler asshole" "Thinks he has the right to tell parents" "How to raise their own children?" "If parents are making their kids fat," "And all evidence says parents who love their kids" "Are making their kids fat," "Then shit!" "You're making it so the government has to get involved." "Penn:" "Oh, that kind." "A lot of this opposition to fast food" "Does arise out of sort of an elitism or a snobbery." "There seems to be this group of people" "Who think that they know what people need" "And what's best for people" "More than those people themselves know," "And that they should be able to tell us what to do" "Really in almost every aspect of our lives." "That snobbery ignores the people to who we provide benefits." "You know, the people that we feed." "I absolutely think that's just wrong." "Penn:" "Hear, hear, Mr. CEO!" "And look, he even throws away his own trash." "You know, at least when the cameras are running." "Let's let mom Becca Badillo sum it up." "I think it's up to everybody to choose what they want to eat." "That's like one of life's most basic choices" "To choose what you want to eat." "Obesity is a hard problem," "But solve it with zoning and taxes?" "We eat too much." "Doesn't matter whether it's home, fancy restaurant, or fast food," "We eat too much, and we eat too often." "We just need to eat less." "It can't be that hard, right?" "Teller doesn't have to eat that whole steak." "He can eat a quarter of it and be perfectly satisfied." "And this burger is delicious," "But now I have had enough." "See?" "It just takes a little knowledge and a little will power." "What it doesn't take is a village." "Star:" "Cut!" "Perfect." "Mmm." "I think" " I think I baubled one of the words" "There during the home, the fast food, that section." "Let's do another one, ok?" "Star:" "We'll run it back and check." "No, no, don't bother." "We'll just" "We'll just do another one right here." "Yeah, we're all set here." "I'm gonna start with eating for a little while, and then we'll go into it." "So before you give an "action," let me get a few bites..." "Out of this." "Then bring the camera up," "And then give me a countdown and "action," and I'll already be eating."