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This application claims priority to application Ser. No. 10/214,868 filed Aug. 7, 2002 which is incorporated by reference herein. The practice of investigating and assessing liability in automobile accidents no doubt dates back to the invention of the automobile. Over the years, the number and dollar value of insured automobile accident losses have greatly increased—the result of increased automobile usage, automobile values, and driving speeds. Similarly, the tort law concept of negligence, rooted in the English Common law and dating back many centuries, has also evolved, with the concept of strict contributory negligence giving way to theories of comparable or comparative negligence. Comparative negligence describes the concept that a claimant's negligence, which to along with an insured's negligence causes the claimant's injury, diminishes the damages that the claimant is entitled to recover. Comparative negligence includes any rule under which the relative degree of negligence of the parties is considered in determining whether, and to what degree, either should be held responsible for a loss. The doctrine of comparative negligence is designed to eliminate the “all or nothing” effect of common law contributory negligence rules (by which any amount of negligence “contributed” by the claimant would bar his or her bars recovery). Comparative negligence rules have developed into three major categories used by the majority of states within the United States, and a number of nations and territories throughout the world: “pure” or “100 percent” comparative negligence rules, “modified” comparative negligence rules, and “slight-gross” comparative negligence rules. Pure comparative negligence allows a claimant whose negligence is not the sole proximate cause of his injury to recover despite his own negligence, but requires that the amount of his damages be decreased in proportion to the degree of his negligence. Under the pure type of comparative negligence a claimant's recovery is not barred even though his contributory negligence was equal to or greater than the defendant's negligence. (For instance, a plaintiff who is 99% negligent may recover 1% of his damages.) Pure comparative negligence has no application where the negligence of the claimant was the sole proximate cause of the injury, or where the sole proximate cause of the accident was the claimant's negligence. Under “modified” or “50 percent” comparative negligence, a claimant's contributory negligence is not a bar to recovery if his negligence was not as great as the negligence of the defendant. As with pure comparative negligence, the damages suffered by the claimant are to be reduced by the degree of his or her negligence. For example, a claimant chargeable with 49 percent of the combined negligence resulting in his injury may recover 51 percent of his damages against a party responsible for 51 percent of such negligence, but if the proportion of negligence chargeable to the claimant is 50 percent or more he cannot recover anything. Under the “slight-gross” rule of comparative negligence, a claimant may recover a proportionate share of his damages where his negligence is not greater than that of the other party. Thus a claimant who is equally negligent with the other party can recover 50 percent of his damages. There are no hard and fast rules for assessing the relative negligence of the parties to a loss. Such assessments depend on the precise circumstances of each particular case. In certain situations one may consider the comparative knowledge of the parties as to the existence of facts or circumstances creating a hazard. For example, if a party had notice of a hazard, consideration should also be given to whatever precautions that party took for his or her own safety, the extent to which he or she should have appreciated the risk as a result of warnings, experience, or other factors, and the foreseeability of injury as a consequence of his or her conduct. One may also take into account unusual and peculiar circumstances, which create a greater risk. Recognizing these and other concepts and consistently applying them to the facts surrounding a particular accident, however, remains difficult for even the most experienced investigator. Today's insurance claim investigator must handle a large number of claims. For each claim, the investigator must perform the difficult and time-consuming task of gathering large amounts of information from a variety of sources, including information from the insured, the claimant and any witnesses and police reports. The investigator must then evaluate each claim based on his or her understanding of the relevant legal concepts, and in particular concepts of comparative negligence. Individual claims must be processed fairly and consistently with other claims resulting from like circumstances. In the past, the components of an investigator's investigation were more often than not “buried” in various locations, for instance in paper files, in computer notes, on audio tapes, etc. This would make the process of locating evidence, comparing statements, and recalling what was said very difficult and time consuming. Without a central repository for the investigation and subsequent negotiations, key elements might be overlooked, depending on the complexity of the claim and independent expertise of the claims adjuster investigating the claim. Another unfortunate result might be that similar to accidents handled by different investigators, or even the same investigator on a different day, result in different assessments. Until now there has been no truly uniform method of assessing comparative negligence, either from claim to claim or from investigator to investigator.

Older migrants reflecting on aging through attachment to and identification with places. With increasing numbers of older migrants adopting a transnational lifestyle or returning to their country of origin following retirement, the sense of attachment to and identification with the places they inhabit remains an under explored field of enquiry. Through an ethnographic approach, this paper seeks to raise awareness of the diversity within a group of older migrants, given the heterogeneity of affective bonds established with places. By highlighting the perspective of older Italian migrants living in Newcastle upon Tyne, UK, this paper illustrates the role of a sense of identification with the context of migration in later life. In referring to migration as a process of transformation, some older Italians re-define their identities, as these become interwoven with the characteristics of the places in which they grow older. However, older migrants' sense of attachment to places also reveals the complexity of aging in the context of migration, when a sense of identification with these is never fully achieved in older age. This paper argues that the notion of aging that these older Italian migrants uphold is not only altered by their experience of migration, but also shaped through their identification with the places they inhabit, given formal and informal practices of identification. Thus, by addressing the determinants for a positive experience of aging in the context of migration, this paper challenges the ways in which older migrant groups are conceptualized in gerontological scholarship.

Dietary sources of energy and nutrients in the contemporary diet of Inuit adults: results from the 2007-08 Inuit Health Survey. To characterize the major components of the contemporary Inuit diet and identify the primary sources of energy and essential nutrients. Dietary data were derived from the 24 h recall collected by the Inuit Health Survey (IHS) from 2007 to 2008. The population proportion method was used to determine the percentage contribution of each group. Unique food items/preparations (ninety-three country foods and 1591 market foods) were classified into eight country food groups and forty-one market food groups. Nutrient composition of each food item was obtained from the Canadian Nutrient File. Thirty-six communities across three Inuit regions of northern Canada. A representative sample (n 2095) of non-pregnant Inuit adults (≥18 years), selected through stratified random sampling. Despite their modest contribution to total energy intake (6·4-19·6 %, by region) country foods represented a major source of protein (23-52 %), Fe (28-54 %), niacin (24-52 %) and vitamins D (up to 73 %), B6 (18-55 %) and B12 (50-82 %). By contrast, the three most popular energy-yielding market foods (i.e. sweetened beverages, added sugar and bread) collectively contributed approximately 20 % of total energy, while contributing minimally to most micronutrients. A notable exception was the contribution of these foods to Ca (13-21 %) and vitamins E (17-35 %) and C (as much as 50 %). Solid fruits were consumed by less than 25 % of participants while vegetables were reported by 38-59 % of respondents. Country foods remain a critical dimension of the contemporary Inuit diet.

Scoring systems and blood lactate concentrations in relation to the development of adult respiratory distress syndrome and multiple organ failure in severely traumatized patients. In 56 patients with multiple trauma with ISSs > or = 33 we prospectively collected data of seven scoring systems (ISS, TS, TRISS, GCS, PTS, APACHE II, SSS) and sequentially determined blood lactate concentrations. These data were analyzed in relation to the patients later developing adult respiratory distress syndrome (ARDS) and multiple organ failure (MOF). Twenty-two patients developed ARDS, and 18 developed MOF. Of the mentioned scoring systems only ISS, PTS, and SSS were predictive of subsequent ARDS, and only ISS and SSS were predictive of subsequent MOF. Lactate concentrations at days 2, 3, and 4 were significantly different between patients with and without subsequent ARDS, MOF, or both. Surprisingly, APACHE II scores did not correlate with subsequent ARDS or MOF, nor did they show any significant relation with lactate concentrations at any time. By stepwise regression analysis ISS, SSS, and lactate level at day 3 were the most significant variables toward the development of ARDS and MOF. It is concluded that scoring systems directly grading the severity of groups of trauma patients have predictive value for late and remote complications such as ARDS and MOF, whereas scoring systems that grade the physiologic response to trauma--although clearly related to mortality--have no such predictive value.

1. Field of the Invention The present invention relates to a rotary electric machine mounted on a vehicle, and in particular, to the rotary electric machine having a rotor and a stator equipped with multi-phase windings for making the machine function as a motor and a generator. 2. Description of the Related Art In recent years, some vehicles have a function for stopping the idle rotation (i.e., idling) of the engine for saving consumption of fuel. In such vehicles, the engine is frequently turned off every time and started up every time the vehicle stops. Because the stop and start-up of the engine is repeated, it is desired that a generator mounted on the vehicle be motor-driven and serves as a starter which has a problem regarding the life of brushes incorporated in the starter. In these vehicles, important parameters necessary when quickly starting the engine are a start-up torque having no rotation and a predetermined torque at which the rotation increases to a value equivalent to the idle rotation. It is desired that fluctuations in the engine-rotation can be stabilized by supplying torque from the generator to the engine. Thus, the generator is required to be motor-driven while the engine rotation can become unstable due to unexpected disturbance of torque of the engine. In these vehicles, motor torque is also required to be generated at least at the level of idle rotation. In general, the vehicle generator is designed to supply required power at an idle rotation of about 1500 rpm. When the vehicle generator is designed in this way, the revolution speed at which extraction of a generated power current becomes possible is about 1000 rpm. When the vehicle generator is motor-driven, a voltage suitable for charging the battery is generated at a revolution speed of 1000 rpm. Therefore, electric current cannot be sent from the battery during motor operation. Hence, a sufficient torque cannot be generated at the revolution speed. As shown in FIG. 1, the torque decreases linearly from a non-rotation start-up torque to a power generation starting revolution speed. Although some torque can be extracted through weakening current-flowing in the field winding of the generator, the torque is not sufficient for the purpose described above. Characteristics of a synchronous rotary machine such as that above are determined by an inductance of a stator, specifically, the number of windings in a stator winding. As shown in FIG. 2, in power generation characteristics, the minimum revolution speed required for initiating the power generation changes depending on the amount of the inductance (the number of windings), and torque and revolution characteristics during motor-driving also change in accompaniment. In a vehicle rotary machine having both power generation and engine driving functions, it is difficult to actualize the characteristics required during power generation and the characteristics required for torque of the engine with the same inductance. A conflicting request is made in that, when the power generation characteristics are given priority, motor characteristics become a state in which the drive torque is insufficient. When the motor characteristics are given priority, the power generation output during idle rotation becomes insufficient. As a conventional technology responding to such requests, a series-parallel conversion rotary electric machine in Japanese Patent Laid-open Publication No. Heisei 4-88900 is known. The series-parallel conversion rotary electric machine provides two sets of stator windings and changes impedance by switching the stator windings between serial and parallel. In another conventional technology, a rotary electric machine is known in which switching elements are disposed at a neutral point and between a high potential and a low potential of a Y-connected three-phase winding in the rotary electric machine. When an abnormality, such as disconnection, occurs in the three-phase winding, the rotary electric machine uses the neutral point in place of the winding of the phase at which the abnormality has occurred. In the series-parallel conversion rotary electrical machine disclosed in Japanese Patent Laid-open Publication No. Heisei 4-88900, a plurality of sets of multi-phase windings are required to be mounted in the stator. Problems occur in that a configuration of the stator becomes complicated and cost rises. A large number of switching elements for switching the winding between serial and parallel is additionally required. For example, compared to six rectifying elements ordinarily required, nine switching elements are additionally required, thereby also contributing to the increase in cost. In addition, the rotary electric device disclosed in Japanese Patent Laid-open Publication No. 2007-99066 is a technology used only during motor-driving and in response to an abnormal situation, and does not meet the above-described requirements. A conventional three-phase winding is driven by only a two-phase winding and three phases are imitated by use of the neutral point. Problems occur such as the rotation not being smooth.

Well, hello everyone, and we’re going to start our fifth topic, that is, Anarchism - our fifth topic in this NPTEL ideologies course 2019-20. Our topic is Anarchism. Now there’s a popular perception that an anarchist is someone who goes around furtively hiding and throwing bombs at institutions or people or into crowds of people - well in fact that form of anarchism is very, very rare. And anarchism itself is a substantial body of political philosophy in its own right, a substantial ideology in its own right. Well, much of anarchism starts from a similar place to Marx. Marx shows that capitalist or commodity producing systems are very powerful and very constricting - they actually shape human nature or restrict human nature to their own ends. Commodity production - capitalism -both shapes and restricts and constricts human nature until its only expression or only permitted expressions serves it ends, serves the ends of capitalist or commodity production. But Marx leaves open the possibility that we can create better systems. If markets are human creations, we can do something about them. And Marx’s intended work on the state, which he never got around to writing - he died before he could - Marx's intended work on the state may well have addressed some of the relevant issues. He died before he could complete that work, but he clearly intended it. And other theorists - liberal theorists for their part - never hesitated to expound there are accounts of the state. Even if they often disagree, as we have seen there are different forms of liberalism, liberals may disagree with one on one another over the state. But anarchists take a very different position; in sharp contrast to both Marx and liberals, anarchists express far greater suspicion about all forms of the state and about other forms of authority both political and religious. And they do that even if many of them criticize capitalism in terms very similar to Marx's own terms. Indeed anarchists were significant participants in 19th century socialist movements; the International Workingmen’s Association, also called the First International, was created when Pierre-Joseph Proudhon’s followers joined forces with Marx's followers in 1864, even though - well their disagreements between Marx’s & Prudhon caused the organization to collapse in 1871. But since then anarchists have at times gained quite substantial political support- for example, among landless peasants in Russia shortly before the 1917 in Bolshevik Revolution - and they have had a strong influence. They have left, anarchists have left a strong influence on the thinking and organization of trade unions in France, in Italy and in Spain as well as in Argentina, Uruguay, and , and that influence has persisted despite decades of fascism in Spain and brutal military régimes in Latin America and Central America. More recently, anarchist ideas have found fresh expression in the Occupy movements in the United States and less obviously in the United Kingdom in the wake of the 2017 financial crash. Such movements, among other things, have focused on something we have already noted: the failure of social democratic parties like the Democrats in the US or Labour in the UK to oppose the policies which caused the crash Now, we need a short update there. The Labour Party is currently - this is 2019 - showing the beginnings of a potentially very strong willingness to restore the social-democratic state, at the very least to revive it to re-strengthen it, and possibly to renationalize, to re-socialize substantial areas of the British economy. But anarchist movements the modern anarchist, the up to date or contemporary anarchist movements, have also pointed out the way, for example, state bailouts for the failed banks, the banks which crashed in 2007 and so on - how these failed bailouts helps the banks to consolidate their hold on land and property - because they simply took over houses and other property on which people could no longer pay their mortgages. We might even see it as a land grab, see that process as a land grab. The failed banks themselves had huge influence on policy and legislation. For example, the crash put millions out of work and those with mortgages often had their homes repossessed by the banks which had lent them money in the first place. Secondly, when the Obama administration, the first Obama administration in the United States, passed what was apparently new legislation on the financial sector, the financiers in Wall Street went out into the street and opened bottles of champagne to celebrate because they had nothing to be afraid of from the new legislation. Anarchists, anarchism’s central concern over episodes like this is like Marxist concern, anarchism’s concern is that such episodes are not episodic but they’re systematic. According to anarchist’ thinkers, established power invariably expands far beyond the limits apparently placed upon it and far beyond what the public would tolerate if they knew about it. Anarchist critics often site a very impressive body of evidence for this. In earlier times the French Revolution soon collapsed in a reign of terror. The Russian Revolution in 1917 had similar results - it resulted in a state which by the time it collapsed in 1991 had almost no public assent whatever. More recently global scandals have emerged over the extent of E-electronic surveillance by the US government including illegal surveillance of its own citizens - and hacking the phones used by heads of government even in friendly states. That process relied upon willing cooperation by major IT corporations. In India, highly repressive colonial legislation has never been repealed or has been repealed, reintroduced, and vigorously used despite severe criticism and damage to the possibility of peaceful dispute resolution. The Armed Forces Special Powers Act 1958, which has even been used with retrospective effect, is an obvious example. Noam Chomsky is perhaps the most famous anarchist thinker today, and he has spent many decades detailing abuses of power by the United States government and its allies. What this indicates is that anarchism retains a profound suspicion of established power of all kinds. This suspicion extends to religious authority here again, the evidence is very substantial. The Roman Catholic Church has publicly admitted covering up several scandals of child abuse including substantial amounts of child sex abuse by priests. And in addition sharp criticisms have been made of concubinage in Hindu caste society as a religiously sanctioned abuse of economic power and social status. I draw that from Hira Singh’s book published in 2014; it’s called Recasting Caste. Now it’s perhaps not surprising that anarchism has had considerable influence in certain countries and regions which have historically had strong religious traditions; these include France and Spain, and almost all of Latin America. The anarchist critique of religion, however, applies to all religions because of their claim to spiritual authority, which in many cases is unquestionable. A great strength of the anarchist analysis of religion is that religion works hand-in-hand with political and financial power Now, the anarchist critique of the religious claim to authority is further strengthened by the fact that religions impose standards of good and evil or acceptable and unacceptable conduct. Those standards are enforced and policed by priests, imams, rabbis and any number of other religious authorities in any number of faiths. According to anarchists, those standards amount to an enormous number of controls on humanity, even to the extent that thinking certain kinds of thoughts becomes a moral crime, a sin. Well we shouldn’t be surprised that anarchism has had global appeal but this has been strengthened by the extent of oppression, suffering, and abusive of power material and spiritual, all over the world. We should not be surprised that anarchist tendencies are found all over the world. Anarchist thinkers have influenced political movements in India, China, Japan, Korea and parts of Africa, not least during the struggles for liberation from colonial domination. In the period immediately after the Russian revolution, anarchist were so popular that the Bolshevik party almost regard them as rivals. And where the state has collapse, which it has done many times in terrible civil wars - many of those result from global drives for natural resources - well, in such conditions are returned to self-generated local community-based organization dispute resolution may well offer fresh hope. Anarchist thinking is also found in records from earlier times, ideas which we would today call anarchist occurred in ancient slave rebellions and they figured in the thinking of diggers, a group called Diggers in the English Revolutions in the 1640s. Anarchist thinking also appeared in the French Revolutions of 1789 and 1848, and the Paris commune of 1871 had an anarchist element; one of the most successful anarchist movements was the one led by Emiliano Zapata in Mexico in 1911. Although Zapata himself was ambushed and killed in 1919 and his mentor Ricardo Flores Magón was imprisoned in the US and murdered in prison, the Zapatista legacy survives in the form of EZLN - The Zapatista Army of National Liberation. In Brazil, a contemporary Anarchist movement is the MST the movement for rural workers. Both aim to regain control of land from large cattle-ranching oligarchies which have dispossessed peasants of communal lands. I should add that today the current Brazilian government under Jair, President Jair Bolsonaro has done a great deal to make the task of regaining control of land from ownership oligarchies very much more difficult. You’ll be aware of the international coverage of this matter. Well, anarchism has had a kind of global appeal despite frequent allegations that it is optimistic and even utopian about human nature. And what is its optimistic view? It is that societies must be founded on and informed by mutual respect, compassion and cooperation. This has even being called a mystical streak in anarchism, a belief in I - quote - ‘almost unlimited possibilities of self-development’. And that has the further implication that all human beings can create a harmonious society and lead harmonious lives. I take that from Anthony Heywood’s [Andrew Heywood’s] commentary on anarchism 2000 or 2007, but leading an anarchist life can take enormous moral and physical courage. Gandhi may well be the outstanding modern example of that. He was partly influenced by the writings of Leo Tolstoy, which have an anarchist element. And he inspired millions of Indians to withstand enormous physical and political violence by the imperial British State without retaliating violently or hating the colonizers themselves. Gandhi in turn inspired leaders elsewhere such as Martin Luther King in the United States. Ccontemporary anarchists have also been influenced by philosophic insights in Taoism and Zen Buddhism particularly on the nature of self-reflection, respect and natural harmony. Now such ideas may be very attractive but anarchist movements have almost never, really never held significant political office, and anarchist arguments for the reform of the state and the economy seemed to figure only rarely in general political life. But anarchist thinking has had and continues to have much greater influence than it is often recognized as having. The reasons for this neglect, which amounts to censorship by silence, are very serious. They also tell us something about the nature of established political and economic power irrespective of the ideological positions taken by those who have such power. Well historically, anarchist greatest successes came during the Spanish civil war. That was a bitter conflict which ended in 1939 with victory for the fascist general Francisco Franco and led to 39 years of fascist dictatorship. During the Civil War the largely anarchist republican movement held substantial areas, most notably the province of Catalonia. And they held them for long enough to establish a functioning system based on and embodying anarchist thought. In the 1930s, Spain already had a mass anarcho-syndicalist Trade union the “Confederacion Nacional del Trabajo”, CNT, and it had another group, the “Federacion Anarquista Iberica”, FAI, which spent most of its time in the political underground. In July 1936 the CNT, the confederation of trade unions in particular, decided to fight the Morocco based Spanish generals who revolted against the government of the day the popular front, popular front government in Madrid. On the 18th of July the government was formed and reformed thrice in one day and the ministers involved then concluded that resistance to the generals would be futile. But the CNT moved swiftly; they seized the weapons held by military garrison and by the civil, by the civil guards, the Guardia Civil. Crucially, the CNT also took control of factories, transport systems and land at that time two percent of land owners owned 67 percent of the land and many of the small holdings were too small even to feed a family. Especially in Catalonia, the locally based and anarchist-inspired economy was highly successful and the provinces whole political life took on anarchistic character which still endures. The workers of the CNT-FAI took over the transport system in the provincial capital Barcelona, and they improved it substantially. The republican side faced enormous political and military odds and was eventually betrayed on several fronts. The Western democracies blockaded Spain under a purported non-intervention agreement which France and Britain favoured; but the United States and the United Kingdom covertly, secretly, helped Franco's forces; that is in work by Noam Chomsky. Secondly, the Soviet Union under Joseph Stalin decided to help Republicans, that is, the anarchist movements, but it did so on terms which effectively destroyed the Republican movement. The Soviet Union Soviet Union insisted on extortion at payments for weapons and thereby bled Spain's gold reserves, and it further required that the anarchists subordinate themselves to the existing popular front. That was the government which had already decided not to resist Franco. Stalin’s motives were utterly instrumental; he could not face the prospect that an anarchist or anarcho-socialist movement in Spain could undermine the Spanish Communist party, and he also feared that the anarchists would take control of British investments in Spain. Britain was a presumed Soviet ally in, I quote, “a democratic alliance” against Nazi, Germany. I have taken those materials from Ward’s book on anarchism 2004 and from Guérin’s book, a detailed book on anarchism, published in 1970 and reissued in 2010. Well, the Spanish government itself may well have been alarmed by the success of the CNT’s rapid moves, moves to reorganize not only agriculture but all work - with the free participation of peasants and other workers. This was an enormous threat even in conception to the Spanish government. The CNT had over a million members at the time in the mid-1930s, and one of its Regional Congresses in Catalonia decided to collectivise land, but the peasants were given a choice in this. The slightly better off ones opted for individual property, while the poor farmers chose collectivization among the workers. Industrial workers - 90 percent chose to join collectives, and that created a rare joint movement of both agricultural and industrial workers. Now under the broad umbrella of the trade unions, the collectives were run as groups of small units, and in accordance with anarchist principles membership was not compulsory. Even those who had opted out could still trade through shops run by the collective or by communal bodies, and they could receive some of the benefits of membership. In Catalonia where there was a tradition of small and medium-sized farms only a few pilot collectives were created. But in the neighboring province of Aragon more than three quarters of the land was socialized. Well, anarchist thinking seems to have been followed as closely as possible. For example, regional planning in Catalonia at that time and in other parts of Spain was federal in nature. Agricultural yields improved immediately; the collectives turned out to be more successful than the communes, and when graduates of agricultural colleges contributed their knowledge, yields rose by between 30 and 50 percent. In the Levant - a particular part of Spain the citrus farmers outperformed big private farmers, even in business dealings and they accounted for 70 percent of the trade. The local bodies further more organized the lectures films and plays, which the largely illiterate peasants relished. They also showed a great degree of solidarity which greatly impressed the visiting British independent Labour Party member Fenner Brockway. The number of people involved in such agricultural self-management soon reached half a million in a total of some 900 collectives. The Catalonian achievements in industrial self-management were even more impressive; Catalonia was the most industrialized area in Spain and for four months in 1936, almost all the factories and public services in the provincial capital, Barcelona, were under workers’ self-management. In fact, many of the private owners who were terrified of the workers had fled. In October 1936, 600,000 attended a trade union congress in Barcelona. And it was highly significant that qualified engineers from the professional classes also participated, unlike their counterparts in other parts of Spain and in Italy. On the 24th of October 1936, the Catalan, the Catalonian, government issued a decree confirming or ratifying the new state of affairs. All establishments with over 100 workers were to be socialized, and in fact farms of all sizes were socialized because many of the farmers were heavily in debt. The new system was highly successful, especially in running urban services and foreign services, foreign observers I beg your pardon, foreign observers were full of praise for the workers’ enthusiasm and commitment. But the successes were undermined even by the pre-Franco Government. Some of its ministers were pro-Soviet, and they feared the prospect of genuine workers’ control. They also decided against the takeover private factories and lands. The agricultural Minister was strongly Stalinist. He was called Vicente Uribe, and he even told private landowners that the Communist party's weapons were at their disposal - and he ensured that they got imported fertilizers which were denied to the socialist, to the socialized farms. Now, Uribe and his fellow Stalinist Juan Comorera, who was put in charge of the Catalan economy, even mobilized small and medium-sized farmers against the, against the Socialist farmers. They disguised large landowners or small holders and then they privatized the organization of Food supplies in Barcelona. As if that were not enough the 11th mobile division under Commander Enrique Lister invaded Aragon with tanks, but even then the peasants resisted - and as soon as the Lister division had gone, they rebuilt their collectives. The communist Party seemed to realize how much it had, how much damage it had done. But whether it is realized, its leaders realized, how much they had reinforced the position of the landowning classes is less clear; perhaps the question arises of whether the Republican government was even on Franco's side, or if it wanted solely to make sure the anarchist movements got nowhere. The Spanish civil war ended in April 1939, and Franco’s regime, which endured for nearly 40 years, was so brutal that after his death the Guardia Civil, the civil guard themselves, had to be protected against violent revenge by the public. The historical record is that anarchist movements have been hated, feared and crushed by all forms of established power, whether by broadly capitalist states or by communist or state capitalist ones, or by established religious authorities. Anarchist ideas, including ideas on political economy, are therefore essential to an understanding of the challenge anarchism poses to all forms of authority. Well, we’re coming to the main anarchist ideas and I’ll give you the headings now. We’ll put up a Powerpoint slide for you once I’ve prepared that. But I’ll briefly introduce the two main types of anarchist ideas first, and then we will look at the main themes in anarchism. Anarchist thought falls into two broad types, collectivist anarchism and individualist anarchism. The greatest difference between the two is in their respective approaches to economics or political economy, but they have a strong common element in what amounts to an implacable opposition to the moderated or managed capitalism favored by social democrats or Keynesians and also to the now-defunct state socialist or state-capitalist systems. The most obvious examples of those were the Soviet Union and until relatively recently China, even though China remains a one-party state, as does North Korea, or more precisely the democratic People’s Republic in Korea. But collectivist anarchists reject social democracy for doing nothing more than soften capitalist exploitation without ending it or even replacing it with a better system. They reject state socialism, on the other hand, for creating exploitation by the state as well as having a monopoly over political power. So, individualist anarchists reject social democracy for in fact, in effect, enabling the emergence of both by private and public monopolies and for limiting property rights and freedoms. 1

[Underestimation of mortality caused by traffic in Mexico: an analysis at the subnational level]. To estimate the potential underestimation of mortality from traffic injuries at the subnational level in Mexico for a period of 15 years and to identify social and economic variables at the state level that could potentially be associated with the quality of statistical classification of deaths. Secondary analysis of validated mortality databases for the period 1999-2013 was conducted. Using multiple imputation models, registries that could potentially be attributed to road traffic deaths were estimated and the potential underestimation of mortality due to this external cause was quantified. A simple correlation analysis was carried out. The potential underestimation of deaths from traffic injuries during the period was 18.85% at the national level, with significant variations by state. From the data analyzed, there was no statistical evidence of any association of the percentage of road traffic deaths underestimation with the variables analyzed. Performance in terms of mortality classification is different at the state level in Mexico. This information is useful for targeting interventions to improve the recording of deaths in the country.

Predicting cattle age from eye lens weight and nitrogen content, dentition, and United States Department of Agriculture maturity score. This research explores the relationship between generally accepted and alternative cattle age-prediction methods and chronological age. Cattle (n = 386) of documented ages ranging from 370 to 1,115 d of age were used. Dentition (DEN), USDA maturity score (MS), lens weight (LW), and lens total N (LN) content were used as possible predictors of age. Correlations with age were determined: LW (r = 0.77); DEN (r = 0.74); LN (r = 0.71); and MS (r = 0.64). Stepwise backward regression was used to generate an age prediction equation: Age (mo) = -21.79 + 17.23(LW, g) + 0.038(DEN). By this equation, 38% of cattle </= 20 mo of age were verified as </= 20 mo of age. Independent measures verified the following percentages of cattle as </= 20 mo of age: LW (20.2%), MS (11.0%), DEN (9.6%), and LN (8.7%). The DEN verified that 87.6% were verified as <30 mo old, and LW verified 81.6% of cattle as <30 mo old. A separate group of cattle (n = 18) ranging in age from 1 to 12 yr were evaluated for lens properties, for which LW (R(2) = 0.91) and LN (R(2) = 0.92) were highly correlated with age. The LW and DEN were the best predictors of age for cattle 13- to 37-mo-old and yielded the most accurate age prediction when used in combination (R(2) = 0.67).

This ancillary study was designed to develop a repository to collect blood to make DNA for studies of genetics in persons who have varying degrees of age-related macular degeneration (AMD). AMD is the leading cause of blindness in the US, accounting for more than 50% of blindness in the population. The Age-Related Eye Disease Study 2 (AREDS2) is study of the role of oral supplements with the vitamins lutein/zeaxathine and/or fish oil (Omega-3 fatty acids)in the treatment of AMD. Approximately 4,000 participants have been enrolled into this study. By studying their genes in these AREDS2 participants, we can have a better understanding of potential mechanisms of disease and how these genes might affect the progression of the eye condition. The genetic factors may play a very important role. This study was currently collecting blood to make the DNA for furture studies while the serum from the blood will be stored also for further analyses. We completed the process of the collection of blood in the third quarter of 2012. Further genetic analyses will be conducted. These valuable data may help us identify targets that may also be important in the therapy of this blinding conditions.

Extremely life-like images have always been of great interest in the prior art. Wax museums startle viewers with the sense of being present in history in the very room with a famous person. Wax museum figures have the disadvantage that they are subject to melting at high temperatures. A method of making mannequins for store windows was proposed in U.S. Pat. No. 2,309,447, issued Jan. 26, 1943 to L. L. Greneker, and titled: DISPLAY DEVICE AND METHOD OF MAKING THE SAME. The Greneker method involved completely shaping a head by sculpturing methods prior to the addition thereto of a flexible material such as paper or fabric coated with photographic impressions. Such coated fabric is then applied in one or more sections and the fabric is cut so as to fit around prominent parts of a face such as the nose and mouth. The cutting of the fabric provided a recess or gore separating the photographically coated fabric into two parts, one half on one side of a recess and the other half on the other side of a recess. The fabric at the two sides of the recess were then fitted and adhesively secured to the surface of the model so that parts of the coated fabric could become in substantial registry with the corresponding contours of the model to the extent possible by such a method of cutting and fitting. The two edges of a recess in the fabric piece were brought into abutment along a vertical line extending from the tip of the nose to the neck in order to form nose, mouth and chin. Other parts of the face were fitted in a similar manner by such cuttings of recesses in the fabric with the objective of bringing all edges into abutment. A disadvantage of the Greneker method can be seen in the great skill required to make the cuts at the right places. Gaps at the joints were to be subdued by filling with pigment. Another disadvantage is that the pigment is not itself a part of the photographically imprinted fabric. However the objective was to make a mannequin which is quite a different objective than to make an image so life-like in its exact representation of an actual human being as to be startling in the substantially complete similarity, as seen in front view. Such substantially complete similarity, which is the objective of this invention, is similar to the immediate recognizability of a excellent photograph, but of course, even more recognizability is achieved because of the 3-dimensional effect, as seen in front view. Wax museum images can be made by a sculptor while looking at a photograph to guide forming the 3-dimensional sculpture. Greneker's method can be used by making the 3-dimensional sculpture while the sculptor is looking at a photograph while the photograph is not attached to the 3-dimensional sculpture. But in the system hereof the photograph is not separated from the sculpture during the formation of the sculpture. In the present invention the new system involves forming the 3-dimensional sculpture of the face-portion of the finished product while the photographically coated flexible face module is not separate from the sculpture but is instead in contact with the sculpture, purposely placed on the sculpture while the sculpture is soft and moldable. The new discovery hereof is that it is possible to press on the photographically coated face module and actually form the 3-dimensional face sculpture by use of such pressing-through the photographically printed face module as the only or main method of sculpting the face. In other words, before the stage of pressing-through the flexible face module no previous face-sculpturing at all is necessary with the method hereof. A particular object is to provide a way to form a human face sculpture with front view accuracy as the sculptor is guided by the picture on the face module. As compared with sculpturing while merely looking at an unattached photograph, the method hereof provides a new art form, making possible great front view accuracy with much greater sculpting speed. Another objective is to provide a new article of manufacture, a finished product which is a face-sculpture having mounted thereon a photographically picture-coated piece of material, the coated material not being cut in its interior parts for fitting over protruding facial features of the sculpture therebeneath, but being substantially of one-piece of substantially uncut material. A very great seeming realism is achieved herein by providing the face image with a recording assembly mounted therein and delivering a reproduction of the voice of the very same being the face image portrays. In the prior art, voice recordings of living beings have not been used with images of those beings to my knowledge.

Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice. It had been reported that exposure to extremely low-frequency magnetic field (ELFMF) induces anxiety in human and rodents. Anxiety mediates via the activation of N-methyl-d-aspartate (NMDA) receptor, whereas activation of γ-aminobutyric acid (GABA) receptor attenuates the same. Hence, the present study was carried out to understand the contribution of NMDA and/or GABA receptors modulation in ELFMF-induced anxiety for which Swiss albino mice were exposed to ELFMF (50 Hz, 10 G) by subjecting them to Helmholtz coils. The exposure was for 8 h/day for 7, 30, 60, 90 and 120 days. Anxiety level was assessed in elevated plus maze, open field test and social interaction test, on 7th, 30th, 60th, 90th and 120th exposure day, respectively. Moreover, the role of GABA and glutamate in ELFMF-induced anxiety was assessed by treating mice with muscimol [0.25 mg/kg intraperitoneally (i.p.)], bicuculline (1.0 mg/kg i.p.), NMDA (15 mg/kg i.p.) and MK-801 (0.03 mg/kg i.p.), as a GABAA and NMDA receptor agonist and antagonist, respectively. Glutamate receptor agonist exacerbated while inhibitor attenuated the ELFMF-induced anxiety. In addition, levels of GABA and glutamate were determined in regions of the brain viz, cortex, striatum, hippocampus and hypothalamus. Experiments demonstrated significant elevation of GABA and glutamate levels in the hippocampus and hypothalamus. However, GABA receptor modulators did not produce significant effect on ELFMF-induced anxiety and elevated levels of GABA at tested dose. Together, these findings suggest that ELFMF significantly induced anxiety behavior, and indicated the involvement of NMDA receptor in its effect.

Over the past twenty years, computer technology has evolved very rapidly. One aspect of this evolution has been a progressively growing demand for increased storage capacity in memory devices. In order to provide high storage density at a reasonable cost, one of the most enduring techniques has been to provide a rotatable hard disk that includes a layer of magnetic material, and a read/write head which is supported for movement adjacent the disk. In arrangements of this type, if the head is exposed to airborne dust, smoke, vapors or other contaminants, these contaminants can progressively build up on the head. Eventually, the buildup becomes sufficient to interfere with the interaction between the head and disk, thereby increasing the error rate until the device will not operate. In order to avoid this problem, most hard disk drives have the disk and head disposed within a sealed enclosure, so that the head and disk are not exposed to any airborne contaminants that may happen to be present externally of the enclosure. This approach works well where the entire hard disk drive is permanently installed in a computer. In another type of system, however, a hard disk is provided in a removable cartridge, and it is desirable that the cartridge not include the read/write head. In this regard, there are advantages to placing a head stack assembly (HSA) and its support structure within the drive which receives the cartridge, rather than in the cartridge. For example, a typical user will have several removable cartridges for each drive. Thus, in terms of overall system cost, it is cheaper to provide a single head stack assembly and support in the drive, rather than to provide several separate head stack assemblies which are each disposed in a respective one of the many cartridges used with that drive. However, this presents problems in regard to keeping the head clean. More specifically, in order to permit the head from the drive to access the disk within the cartridge, the cartridge is not provided with a sealed enclosure of the type discussed above. Instead, the cartridge is provided with an opening through which the head of the drive can be inserted into the cartridge. In some cases, a movable shutter is provided to obstruct the opening when the cartridge is not in the drive, but the shutter is open when the cartridge is in the drive. Thus, in either configuration, when the cartridge is in the drive, the opening gives not only the head but also ambient air access to the disk and head. Consequently, any dust, smoke, vapor or other contaminant carried by the ambient air can get inside the cartridge enclosure, and the operational surface of the head can quickly develop a buildup of contaminants. The effect of this buildup can be ameliorated to some extent by keeping the storage density of the hard disk in the removable cartridge at a relatively low level, in comparison to the levels used for hard disks located within sealed enclosures. However, as mentioned above, the commercial marketplace is exhibiting a strong and progressively increasing demand for high-density storage in a removable cartridge. A further consideration is that existing high-density read/write heads typically have an operational surface with recesses therein. While it is not too difficult to clean the outermost portions of the operational surface of such a head, it is more difficult to clean other portions of the surface which are within the shallow recesses. As contamination collects in the recesses, it can significantly degrade system operation.

I propose to engage in several activities, all designed to illuminate the etiology of neoplastic disease. I will supervise case-control studies in test of specific etiologic hypotheses suited to that method. The first will be of pancreas cancer in relation to diet and atopic disease, and of aggressive (metastatic or invasive through the myometrium) endometrial cancer in relation to exogenous estrogen use. I will continue to develop a registry of twins with cancer and perform co-twin studies of breast cancer, colon and other GI cancer, malignant melanoma, and other neoplasms. I will perform follow up on unaffected twins in relation to their stated exposures, and utilize population-based twin registries in California and Sweden for various adjunct studies. I will begin a cohort study in high risk individuals designed to elevate the determinants and implications of acquired benign pigmented lesions. I will continue to use cancer and registry information for descriptive studies, including estimation of the observed and expected rates of conjugal site-specific cancer, of the incidence among those residing near geographic foci of contamination with toxic wastes, and of disease-specific concordance in twins and the implications for interpretation of familiality and heritability. Finally, I will design a program to facilitate laboratory investigations making use of material from twins in the registry; such a program could provide a unique integration of high quality epidemiologic study design and "state of the art" lab techniques.

Date: Tue, 13 Jan 2004 11:49:31 +0000 From: christopher morgan Subject: Straigt-to-hell / Chapter 1 / Science Fiction If you are under age, or live in an area where reading tales of male sex is illegal, or if you're not into this type of story, please leave. Hi guys, this is my first attempt at a story for Nifty. I'm not sure if it's any good. Please email and let me know! My email is chrism27@hotmail.com Chapter 1 The Pentagon "Status?" The General's eyes were hard and tense, and his voice was clipped. "Sir, the targets have been acquired, awaiting permission to fire at your command." The Colonel's response contained a similar amount of tension. The special operations command center was fully staffed, but the electronic hum of computers and air-conditioners could be clearly heard in the background. The room was almost silent, the military personnel concentrating on the information displayed on their consoles. The General let out a deep breath and raised his eyes to the gallery overlooking the command centre and a man in uniform who stood there. The Chairman of the Joint Chiefs of Staff looked back and nodded slowly but firmly. The General turned back to look at his second in command, his movements now filled with resolution. "Very well Colonel, permission is given" he said. South Africa The squadron was flying low over the suburbs of Cape Town, fast approaching their destination. The weapons were ready to go, and once the firing order was received over the satellite link-up, over 40 `smart' missiles were launched from the planes, and accelerated towards their target. There were no air defences around the three-story, 1980s office-building. There were no dud missiles either, and all 40 of them slammed into the target, engulfing the building in hugely powerful explosions. When the squadron flew over a little while later, they reported the mission a success. The Pentagon The destruction of the target was confirmed 30 minutes later by satellite, and the tension in the command center lessened almost immediately. They thought it was over, the crisis had been averted. There would be a considerable amount of behind-the-scenes diplomatic work to be done, but the mission had been accomplished. South Africa The emergency services had already been scrambled and were on their way to the destroyed building. It appeared that no-one in the surrounding area had been seriously hurt, but it was assumed that anyone who had been inside would have been killed. The building had been rented by a small genetics company for R&D purposes, and the owners would be contacted as soon as possible. There might be dangerous chemicals and pollutants that would need to be dealt with carefully during the clean-up. However, the city officials had problems contacting the owners. In the coming months fraud investigators would attempt to unravel the network of paperwork surrounding the company, but would have no luck. No problems were reported however, and tests for the most common pollutants that a genetics company might use proved non-existent or negligible. The central government discouraged any questions on how exactly the building had been destroyed. No further action was taken. The Oval Office -- 1 year later "Mr President, the final issue on the agenda for today is the round up the WhiteMight terrorist cells in Alabama", the Director of the CIA took out a folder from his briefcase and laid it upon the table. "Sir, we've uncovered some disturbing links to terrorist groups in South Africa, including the September Group" he continued. "The September Group? I thought we took care of that last year, it took enough effort to convince the South Africans not to go apeshit over us invading their airspace and destroying an office block in suburban Cape Town. I thought it was all over" the President looked up from the briefing papers on his desk impatiently. The security review was almost over and he had a meet and greet session with some important donors in ten minutes. "Yes sir, but some of the details appear to suggest that members of WhiteMight have been in contact with September Group people recently" The Director replied. "We're keeping an eye on it." Center for Disease Control, Atlanta -- 1 year later "OK people what's the latest on the South African flu situation?" The senior staff were sitting around a conference table, the coffee had been poured, and they were settling in for the long haul. "Well, we've gone way past epidemic figures as of the end of last week" replied the chief epidemiologist, "but so far it's still proving a remarkably mild version. It puts people out for a few days, but death stats are lower than expected. We are still figuring it should burn out within three months, it's already tailing off in Europe, and most of Africa and Asia dealt with in last year". "Did you hear the reports from Virginia?" responded another department head. "They're detecting high levels of antibodies in apparently non infected subjects, even in virgin field populations, Max Sheffield in Chicago is worried we could be looking at something new". "That's actually something I wanted to raise with you" The head of Virology spoke up, clearing his throat. "This could be potentially serious, if we can confirm it that is. We've done the initial analysis of the virus and, well...we've found signs of engineering in the RNA. It's very subtle, and as I said, it's not confirmed, but if it's true, then we could be looking at the possibility that the virus is not entirely a natural occurrence." The conference room went silent. University of Chicago -- 3 months later Michael Andrews ran from the basement cleanroom decontamination suite, up the stairs, and straight into Professor Sheffield's office. "George!" Michael's voice was breathless and strained. "Forty-three of them died last night, all male". He stopped and gulped, the fear in his expression obviously apparent. Professor Max Sheffield, half stood from his desk. The expression on his face was fixed, under tight control, but the color drained from it rapidly. "Are you sure? Michael..." "Max, the primates have the same level of protein shielding, the same generation of the virus, that infected humans will have within two months. Whoever designed it timed it closely Max, God knows how they did it, but this is terrifying!" Michael's voice was rapidly approaching hysteria. "I'll get right onto the CDC." Replied the ashen faced professor, his had shakily reaching out for the telephone. "Max, what are the infection survey results? I know you were informed, that's why you went to the meeting in Washington wasn't it?" Michael's voice became quiet, his eyes locked onto the professor, refusing to let him go. The professor blinked and look down in defeat, "Michael, those are confidential, I'd be breaking the law if I..." "Max, tell me" Michael cut off his protestations. The professor sighed and rubbed his forehead, he looked every bit his 53 years. He looked up at Michael and saw the intense young man staring at him unrelentingly. He thought to himself, what was the point anyway? He'd know within two months. "Michael, everyone who has been tested, 7.5 million people in the US alone, and millions more worldwide have tested positive. We're looking at 100%". Michael became completely still, "There's more" he said. "The fifty-seven per cent of the monkeys who survived" "Yes?" enquired the professor hesitantly, not sure he wanted to hear the rest. "They were all female, apart from 7 males" Max replied. "Correlation?" the professor asked. "I talked to Jane Healy, she know the monkeys almost individually. She said that all seven males showed a preference for homosexual activity, they were the only males to survive". "Oh my God" said the professor, shocked. "You know what this could mean don't you? Hell, what it probably does mean!" Micheal's eyes began to fill with tears. "I've got to make that phone call". The Professor reached for the handset again.

Physical health and mental disorder in elderly suicide: a case-control study. The psychological autopsy method was used to study 95 cases of suicide. Ninety-five comparison subjects matched for gender, age, region, and date of death were selected from the death register. This study showed that suicide cases did not differ from controls with regard to the number of chronic health problems and, compared to the suicide cases, the controls had less functional autonomy six months prior to death. If minor and sub-threshold depression cases were included, 74.7% of the suicide cases would have been considered as having a mental health disorder compared to 12.6% in the control group. When the effect of other co-variables were controlled for, multivariate analysis showed that suicide cases and controls did not differ according to marital status, education, income, and living arrangement. Furthermore, suicide cases were no more likely than controls to seldom meet with family members or friends or to have been isolated during the six-month period preceding their death. Our findings suggest that detection of psychiatric disorders, mainly depression, must be included in late life suicide prevention strategies.

To meet the demand for higher integration density and operating speed of LSIs, the effort to reduce the pattern rule is in rapid progress. The wide-spreading flash memory market and the demand for increased storage capacities drive forward the miniaturization technology. As the advanced miniaturization technology, manufacturing of microelectronic devices at the 65-nm node by the ArF lithography has been implemented in a mass scale. Manufacturing of 45-nm node devices by the next generation ArF immersion lithography is approaching to the verge of high-volume application. The candidates for the next generation 32-nm node include ultra-high NA lens immersion lithography using a liquid having a higher refractive index than water in combination with a high refractive index lens and a high refractive index resist film, EUV lithography of wavelength 13.5 nm, and double patterning version of the ArF lithography, on which active research efforts have been made. As the pattern feature size is reduced, approaching to the diffraction limit of light, light contrast lowers. In the case of positive resist film, a lowering of light contrast leads to reductions of resolution and focus margin of hole and trench patterns. For mitigating the influence of reduced resolution of resist pattern due to a lowering of light contrast, an attempt is made to enhance the dissolution contrast of resist film. Chemically amplified resist compositions comprising an acid generator capable of generating an acid upon exposure to light or EB include chemically amplified positive resist compositions wherein deprotection reaction takes place under the action of acid and chemically amplified negative resist compositions wherein crosslinking reaction takes place under the action of acid. Quenchers are often added to these resist compositions for the purpose of controlling the diffusion of the acid to unexposed areas to improve the contrast. The addition of quenchers is fully effective to this purpose. A number of amine quenchers were proposed as disclosed in Patent Documents 1 to 3. With respect to the acid labile group used in (meth)acrylate polymers for the ArF lithography, deprotection reaction takes place when a photoacid generator capable of generating a sulfonic acid having fluorine substituted at α-position (referred to “α-fluorinated sulfonic acid”) is used, but not when an acid generator capable of generating a sulfonic acid not having fluorine substituted at α-position (referred to “α-non-fluorinated sulfonic acid”) or carboxylic acid is used. If a sulfonium or iodonium salt capable of generating an α-fluorinated sulfonic acid is combined with a sulfonium or iodonium salt capable of generating an α-non-fluorinated sulfonic acid, the sulfonium or iodonium salt capable of generating an α-non-fluorinated sulfonic acid undergoes ion exchange with the α-fluorinated sulfonic acid. Through the ion exchange, the α-fluorinated sulfonic acid thus generated by light exposure is converted back to the sulfonium or iodonium salt while the sulfonium or iodonium salt of an α-non-fluorinated sulfonic acid or carboxylic acid functions as a quencher. Further, the sulfonium or iodonium salt capable of generating an α-non-fluorinated sulfonic acid also functions as a photodegradable quencher since it loses the quencher function by photodegradation. Non-Patent Document 1 points out that the addition of a photodegradable quencher expands the margin of a trench pattern although the structural formula is not illustrated. However, it has only a little influence on performance improvement. There is a desire to have a quencher for further improving contrast. Patent Document 4 discloses a quencher of onium salt type which reduces its basicity through a mechanism that it generates an amino-containing carboxylic acid upon light exposure, which in turn forms a lactam in the presence of acid. Due to the mechanism that basicity is reduced under the action of acid, acid diffusion is controlled by high basicity in the unexposed region where the amount of acid generated is minimal, whereas acid diffusion is promoted due to reduced basicity of the quencher in the overexposed region where the amount of acid generated is large. This expands the difference in acid amount between the exposed and unexposed regions, from which an improvement in contrast is expected. Despite the advantage of improved contrast, the acid diffusion controlling effect is rather reduced. As the pattern feature size is reduced, the edge roughness (LWR) of line patterns and the critical dimension uniformity (CDU) of hole patterns are regarded significant. It is pointed out that these factors are affected by the segregation or agglomeration of a base polymer and acid generator and the diffusion of generated acid. There is a tendency that as the resist film becomes thinner, LWR becomes greater. A film thickness reduction to comply with the progress of size reduction causes a degradation of LWR, which becomes a serious problem. The EUV lithography resist must meet high sensitivity, high resolution and low LWR at the same time. As the acid diffusion distance is reduced, LWR is reduced, but sensitivity becomes lower. For example, as the PEB temperature is lowered, the outcome is a reduced LWR, but a lower sensitivity. As the amount of quencher added is increased, the outcome is a reduced LWR, but a lower sensitivity. It is necessary to overcome the tradeoff relation between sensitivity and LWR.

"In Japan there is a chest called the nagamochi... that treasures are kept in." "Favorite clothes from childhood... or things that a girl takes with her when she gets married." "Most people keep the chest locked." "It's usually kept in the back of the closet." "Memories are sealed in the chest." "Cherished memories and glittering times... live forever in the corner of darkness." "Are you ready?" "No, not yet." "OSEI." "OSEI." "WHERE ARE YOU GOING?" "I'M GOING SHOPPING." "Mister, let's play hide-and-seek." "So come on." "Let's play." "Are you ready?" "Kakutaro, who suffers from an illness... did not work and stayed home all day." " Are you ready?" " Yes, we are." "Lying down in a dark space... inside a large nagamochi that smelled of camphor... he was filled with a nostalgic sweetness... that almost moved him to tears." "Can you come out, mister?" "I can't find him." "It's no fun." "Do you want to go outside and play now?" ""I should come out now."" "Kakutaro wanted to come out to surprise the children." "But the tightly closed lid did not budge an inch." "I'M HOME." "When Osei came home, Kakutaro was no longer able to talk... as he became more suffocated every moment in the nagamochi." "OSEI." "HELP ME." "IT'S ME." "What happened to you?" "Oh, you were playing hide-and-seek." "You're so mischievous." "Keep your chin up, ma'am." "It must have been hard for you." "What bothered her most... was the memory of the weak feel of her husband... when she closed the lid of the nagamochi." "NOT APPROVED" "BEGINNING OF THE SHOWA ERA" ""Notification:" "Name of the author, Rampo Edogawa." ""Real name, Taro Shirai." ""Current address, Tokyo-city, Hongo-ku, Tsumagoi-cho 3." ""Occupation, novelist." ""Publication of 'Osei Tojo'..." ""the work written by the above person..." ""shall be banned as a result of censorship." ""The authority found that the novel..." ""is likely to be detrimental to public morale." ""In case you do not obey the authority's decision..." ""the author, Rampo Edogawa..." ""and the publisher, Masashi Yokomizo..." ""are to be immediately arrested and jailed."" "Is there anything you would like to say regarding this decision?" "I will obey the decision." ""Furthermore, any published works by Rampo Edogawa..." ""must not be reissued..." ""until further notice is given..." ""by the officer in charge of this case." ""When you write a new work..."" "Here I am again..." ""THE PHANTOM WITH TWENTY FACES" WRAP PARTY" "Mr. Tagawa, the producer, is over there." "Sir... thank you very much for taking time to come to the party." "In this business, we are obligated... to hold a party like this even if we don't want to." "This is how the life goes." "The movie turned out to be a good one." "Have you seen it yet?" "No, not yet." "You would rather see it now than complain about it later." "I heard that the publication of "Osei Tojo" has been banned." "In times like these... you are better off writing "The Phantom with Twenty Faces."" "It really is a bad time, isn't it?" "Could you please give a speech to the guests now?" "No, I prefer not to." "You don't have to take it that seriously." "No one likes to give a speech in front of many people." "Director, this is Mr. Rampo Edogawa." "How do you do?" "And this is Mr. Akechi in the next series." "This is Mr. Twenty Faces." "How do you do?" "Pleased to meet you." "Excuse me, can we go through?" "Excuse me." "This way, sir." "Yes, this way." "Sir, could you please pose for the camera?" "Could you hold the microphone?" "That's good." "Ladies and gentlemen..." "Mr. Edogawa is here tonight, and he will make a speech." "Please welcome Mr. Rampo Edogawa." "I am Rampo Edogawa, who wrote the original book of this movie." "I am particularly fond of Kogoro Akechi, and..." "I am not used to talking to people like this, but..." "Just now, I was introduced to the actor... who plays Akechi in the next series... and he was great, and..." "Thank you very much." "Thank you for making the speech." "Mr. Yokomizo is waiting for you there." "If you don't mind, please take this with you." "Thank you very much." "Sir, it was a good speech." "Here I am again." "I felt somewhat cold presentiment and I was scared." "Dull darkness has covered my entire world... and I wondered if I might walk in this darkness... in a large circle forever." "I was not scared of the outside world... but I was scared of my own uncertain strides." "Where does this darkness in the forest that confines me end?" "Are you roasting sweet potatoes, sir?" "I am burning something useless." "What are you going to do with the heroine?" "You haven't even introduced her yet." "That was her destiny." "I am not going to write anything for a while." "I think I will go on a wandering journey for a while." "Please don't look for me." "Please have a look at this article." ""Accident or Murder?"" "The woman's name is Shizuko." "The more you read this article... the more similarities you find with your novel." "As publication of this novel was banned... the woman could not have read it." "You see, your novel has power to change even reality." "The police concluded it was an accidental death... but it is too similar to the novel." "Her sick husband at home played hide-and-seek with children... while both the wife and the maid were not home." "He was suffocated to death in a nagamochi." "Everything that happened... was almost identical to what you wrote in the novel... the novel no one is supposed to know... as if details are compared with each other." "What happens to that woman now?" "How should I know?" "You should keep writing." "The woman you wrote about could not be eliminated." "She has appeared in this world." "Who cares about the censorship?" "You should not turn your main character adrift in the street." "ANTIQUES, BOOKS" "I am just looking..." "That one is dead." "It has been broken for a while, producing no sound." "Is that right?" "If you like, you can take it." "It is not for sale anyway." "I displayed it in the shop... because I wanted to give it to someone who liked it." "No, I cannot take it for nothing." "How much is it?" "I really don't want to charge anything." "I have been taking good care of it since I was a child." "If you don't mind, please keep it." "I promise that I will take good care of it." "Thank you very much." "You should not buy anything from a shop like that." "That woman, who was picked up by her husband... killed him and took over the shop." "How can she stay there as if nothing has happened?" "Mind your own business." "WE ARE CLOSED DUE TO UNAVOIDABLE CIRCUMSTANCES" "GET OUT OF HERE, MURDERER" "UGLY WOMAN, YOU SHOULD BE EXECUTED" "I have to find a way out of the forest." "Beyond the darkness..." "I don't know if the sun shines or cold wind blows... but I must find a way out of the forest." "Why are you here?" "Did you follow me?" "I am terribly sorry." "I had a feeling... that you were going to disappear for some reason." "I could not help following you." "You are Mr. Rampo Edogawa, aren't you?" "Please look after the music box." "I must go." "To be frank with you, I am writing a novel about a woman." "But when I try to think about the heroine... the picture of you always comes up in my mind." "A piece of the picture of you instantly expands in my mind... and I cannot help it." "Something like this has not happened to me for a long time." "It has come to the stage... where I cannot continue to write unless I think about you." "That is why I followed you." "Please don't worry about me, and leave me alone." "So long." "DETECTIVE KOGORO AKECHI SERIES "THE PHANTOM WITH TWENTY FACES"" "I am a master of disguise who has twenty faces." "People call me The Phantom with Twenty Faces." "You have quietly witnessed the history of some 5,000 years." "If you have a soul, I want you to talk to me about it." "Hold up, Twenty Faces." "Who the hell are you?" "I am nobody." "I am Kogoro Akechi." "What?" "Kogoro Akechi is supposed to be in the U.S. now." "Akechi returns to Japan from the U.S. within a day... if there are any villains." "Sir, have you met Shizuko yet?" "Yes, I have." "So, what happened?" "So, then..." "I found a nice mirror in her antique shop." "Can you go there and buy it for me?" "You'll know which one, as it is the only one." "Sorry to ask you a favor of a private matter." "I have been too busy." " Is that all you want me to do?" " That's right." "How do you like it?" "It's turned out to be good, hasn't it?" "Look how handsome Akechi is." "You said he was your other self." "We had to be very careful with him." "Can't you change that line?" "What line?" "You can't make an unreasonable request... as this has already been completed." "That's why I asked you to see it as soon as possible." "You know, with movies, directors have the creative right... and actors have the portrait right." "Things become more complicated once a movie has been completed." "Excuse me." ""I came to deliver what you ordered." ""I waited for a while and then decided to leave." ""I am looking forward to your excellent work."" "TO MR. RAMPO" ""Dear Mr. Rampo Edogawa, I would like to see you..." ""and I will be waiting at Nezu Shrine at 3:00." ""Shizuko."" "I didn't think I could see you again." "I am sorry to have asked to you to come." "I wanted to apologize for what I did the other day." "I have to apologize to you, too." "I was almost delirious, and I am really sorry about it." "The other day..." "Mr. Yokomizo brought me your novel, and I read it." "After reading it, I found my mind at wonderful peace... as if I was protected by someone I loved." "Thank you so much." "Can you follow the car ahead?" "It is getting dark, isn't it?" "In the soundless, fragrantless... and feelingless darkness in the forest..." "I felt all my senses, hearing, smelling, and feeling... were converging into a single sense." "This is my other self, Kogoro Akechi." "On that day, Akechi received a strange anonymous letter." "The letter mysteriously requested him... to investigate this lady." "How can she behave that prudishly?" "She is only a mistress." "Do you know her?" "She is the one who is said to have killed her husband." "Instead of being caught, she now enjoys the life... as a mistress of a duke, with her own driver." "Wealth, rumor, and madness were involved." "Akechi smelled death there." "The place of the smell of death was the mansion of Duke Ogawara." "Are you all right?" "What were you doing in a place like this?" "You can see what I was doing." "I was experimenting with parachuting." "Come this way." "Hello, master." "Tend to his wound." " I am sorry to trouble you." " What are you talking about?" "That is my late mother." "She is beautiful." "I love this painting." "I see the transient glow of life in her." "I used to enjoy watching my mother standing in the forest." "How is your wound?" "There is nothing to be worried about." "Thank you very much for treating me." "I am holding a small festivity... to celebrate my 60th birthday on the weekend." "Would you like to stay here until then?" "I'd love to, if I don't cause any trouble." "Thank you." "It is my way to have the game cooked in front of me." "I hope you don't mind." "The fresher the food is, the better it is." "I like you, young man." "It is also my way not to pursue those who go away... and not to refuse those who come." "So if you don't want to stay anymore... don't oblige yourself to stay." "Pollen of Mandoragora..." "A deadly poison... that kills you within a minute after licking it." "But it makes a good aphrodisiac if you smoke it." "I like taking poisonous substances... into my body like this." "That one is dead." "I have been taking good care of it since I was a child." "It has stopped producing any sounds since I moved here." "It is my job to watch him ride a horse from here." "Day after day, for hours, I have to watch him from here." "Mr. Akechi..." "If you give me some time, I promise that I will..." "Mom!" "Don't look at me!" "Your daytime job must have finished." "Sleeping with you every night... does not bring me pleasure any longer." "Why do you think I picked up a woman like you... who killed her husband?" "Have I ever asked you to behave like a good person?" "All I want is the night dream that is possessed by a demon." "For you, a stranger to any sweet dreams..." "I'll show you something special tonight." "The only thing I lack... is the smell of a young woman's skin." "A telegram." "A telegram for you, Mr. Rampo Edogawa." "May I come in?" "How could this happen?" "Someone is probably harassing me." "These are the traces of my husband's nails." "Please... please help me." "I don't want to be on my own." "Please hold me." "There is nothing I can do for you." "I know that I should not rely on you... but I thought you would stay close to me." "I have to keep writing my novel." "I am sorry I have to go." "Ladies and gentlemen, thank you very much for coming." "I would like to call this party "One Night Dream."" "Let me read aloud my beloved poem by Poe... to express my sincere gratitude." ""By a route obscure and lonely..." ""Haunted by ill angels only..." ""Where an Eidolon, named Night..." ""On a black throne reigns upright." ""I have reached these lands but newly..." ""From an ultimate dim Thule..." ""From a wild weird clime, that lieth, sublime..." ""Out of Space... out of Time." ""Bottomless vales and boundless floods..." ""With forms that no man can discover..." ""for the dews that drip all over." ""Their Ione waters, Ione and dead..." ""Their still waters, still and chilly..."" "That body has already been returned... to the earth and the heaven." ""Time passes by..." ""just like a sleepless night that chokes me up." ""I want to drift somewhere far away..." ""where no one can reach me..." ""being embraced by someone's voice who is calling me." ""I want to drift to somewhere far away like a dream."" "Mr. Akechi." "I was so occupied with this that I didn't notice you were there." "I was so occupied with this... that I didn't notice you were there." "My pleasure in life... is to control the minds of other people." "You should try, too." "He loves the grass here." "It seems I made a mistake by letting you stay." "She seems to be very fond of you." "Since you came, she has regained her natural self." "Now it is time for an entertainment." "Once the funeral arrangements have been made..." "I will leave here, too." "Most likely, we will have to close this mansion soon." "Mr. Akechi." "May I speak with you for the last time?" "I am the one who killed the duke." "You knew that, didn't you?" "Why didn't you wait a little longer?" "I would like to ask you a favor." "I lost my husband in this nagamochi." "You want me to go in there, don't you?" "Will you go in there?" "Akechi, you should not go in there." "I don't need any instructions." "Instructions..." "Hello, can I help you?" "Where is Shizuko?" " What?" "Shizuko?" " Where is she?" "She is staying at a duke's place in Atami." "A duke..." "Look..." "Today she sent us another article left by the duke." "Where is the nagamochi?" "Nagamochi?" "That must have been sent to Atami when she moved there." "Sir?" "Sir?" "Yes, I will go in there." "You said you would get me out of here one day." "If I thought I could start a new life somewhere far away..." "I couldn't be happier." "I thought, if I could live in a dream of a person I love... how happy I would be." "But... why did you leave me all alone?" "Don't, Shizuko!" "I wanted to be embraced... by Mr. Rampo." "Akechi..." "You finally made it." "I'm happy you came to see me." "It is all right if I keep everything inside me, isn't it?"

Catch-up growth in children treated with home enteral nutrition. This study was designed to determine the effect of home enteral nutrition on the outcomes of growth and the relationship between growth and entrance anthropometric criteria. We reviewed the medical records of 78 consecutive children (median age, 20 months) who were enrolled in the home enteral feeding program at the Alberta Children's Hospital (Calgary, Alberta, Canada) between 1993 and 1995. Weights, heights, and weight-for-heights were expressed as Z scores, using the Centers for Disease Control and Prevention anthropometric growth curve software. To evaluate growth outcome, the total group was further subdivided using anthropometric criteria into appropriate, wasted, or stunted at the time of entry to the program. In a subgroup of 36 children on whom anthropometric data was available for a median length of 5.7 months, Z scores were compared at 3 points in time: before entry, at time of entry, and last follow-up. Patients were classified into five main groups: 11 (14%) had pulmonary disease, 26 (33%) had a gastrointestinal disorder, 21 (27%) had congenital defects, 10 (13%) had a neurologic disorder, and the remaining 10 (13%) had a variety of other illnesses, including malignancies and metabolic disorders. Patients were on the program for a median duration of 8.9 months. It was found that during the period of support within the program, enteral feeding was successful in improving weight-for-age Z scores by 0.42 standard deviations but the effect on height-for-age Z scores and weight-for-height Z scores did not reach significance for this population. The subgroup of 36 children on whom longitudinal anthropometric data was available before entering the program was found to have had a significant drop in weight Z scores between the time before program entry (median length of time, 5.7 months) and the time of program entry, which indicates that these children were falling off the growth curve before commencing enteral feeding. To evaluate growth outcome, the total group was further subdivided using anthropometric criteria into appropriate, wasted, or stunted at the time of entry to the program. In the group of appropriate growth patients, while in the program, 50% had catch-up growth for weight (positive change in Z scores) and 33% for height. In the wasted patients, 92% improved their weight percentile and 75% their height percentile. In the stunted group, 71% had catch-up growth for weight and 74% for height. We concluded that the enteral feeding program was able to promote catch-up growth or maintain growth along percentiles in the majority of children.

Gelatin is a protein material produced by hydrolysis of collagen from animal bones and connective tissues. Gelatin has served as an encapsulating material, a coating for pills, an emulsifying agent, a coating for photographic materials, a bacterial culture medium, a component of printers' rollers and hectograph plates, an ingredient of popular desserts, and for many other widely varied uses. One common use for gelatin is in the manufacture of soft gel capsules for the delivery of active ingredients. Although gelatin is generally strong and tough, its extensibility and flexibility are generally low. In addition, since gelatin is derived from animal sources, there are often inconsistencies in product quality from batch to batch. The physical and chemical properties of gelatin are a function of the source of the collagen, method of manufacturing, conditions during extraction and concentration, thermal history, pH and the chemical nature of impurities and additives. Moreover, during storage, gelatin often undergoes a crosslinking reaction which in turn changes the dissolution character and the drug bio-availability characteristics. This shortens the useful life of the gelatin. Thus, mechanical failures of gelatin soft gel capsules are often encountered. Additionally, the use of animal derived materials, such as gelatin, has come under regulatory review due to concerns regarding the transmission of animal based illness. Accordingly, new materials are desired which can function as replacements for gelatin, particularly gelatin based films useful for manufacturing soft gel capsules and the like.

Labelling of oviduct nuclear and nucleolar proteins during estrogen induced differentiation. The effect of secondary stimulation with estrogen on synthesis of nuclear and nucleolar proteins is studied in chick oviduct. Isolated nuclei and nucleoli have a protein/DNA ratio of 5.2 and 5.6, respectively. 35% of nuclear and nucleolar protein is recovered in the histone fraction after hydroxylapatite chromatography. Gel electrophoretic separations of nuclear and nucleolar nonhistones are largely similar as to visible bands and distribution of radioactivity. Nucleoli bind 1.4 times more [3H] estradiol as compared to whole nuclei. Nucleolar histones are labelled slightly more actively with [3H] leucine than nuclear histones; nucleolar nonhistones are labelled about 3 times more actively than nuclear nonhistones. An 18 hour secondary stimulation with estrogen increases the radioactivity of histones by 6-fold and that of nonhistones by 2.5-fold in whole nuclei as well as in nucleoli. Stimulation appears to increase preferentially radioactivity of nonhistones at 50 000 daltons. As this change is observed in whole nuclei and nucleoli and is not reduced with hydroxyurea, it is suggested that this may be related to a gross structural reorganisation of chromatin induced by the hormone.

Many services offered to users via the Internet, such as email services, provide a web interface (“webclient”) that allows users to interact with a server using a web browser. User connectivity to such servers is facilitated by one or more web servers (typically Hypertext Transfer Protocol (HTTP) servers) that retrieve data in response to user web page requests and host web applications. Mail servers and web servers are typically located in a data center or some other facility remote from the user. Redundancy is usually built into such systems, with redundant servers providing service in the event of a failure of a primary server and redundant communications links connected to the Internet to provide service in the event of a failure of one or more communications links. When a user attempts to access an email system using a webclient, the webclient connects to a web email application hosted by an HTTP server and sets up a communications session with the HTTP server. Upon initiating such a session, some form of authentication is normally required by the HTTP server. This may take the form of a username and password combination, access key, token, or some other form of user identity verification. Upon authenticating the user, the HTTP server may provide access to the user's email account and information on the mail server via the web email application hosted by the HTTP server. If there is a failure of the HTTP server hosting the web email application being used by the webclient, or if the connection between the HTTP server and the webclient fails, the webclient is likely to be directed to a backup HTTP server hosting another web email application. When this happens, the user may have to provide authentication information again because the user's authentication information has not been received by, or stored at, the backup HTTP server.

The EU Nitrates Directive states a threshold level of 50 mg/l nitrate in groundwater. In the Netherlands, compliance is currently checked in the upper one meter of groundwater. A draft EU monitoring guideline leaves open the possibility to check compliance in the upper five meters of groundwater. The nitrate concentration in groundwater in the Netherlands has significantly decreased between 1996 and 2004 due to policy measures. Nitrate concentrations are below the EU threshold level in large parts of the Netherlands. In sandy soils, however, the average nitrate concentration still exceeds the 50 mg/l value in the upper one meter of the groundwater. Additional measures are required to meet EU threshold values. Changing the checking level from the upper one meter to the upper five meters of groundwater could provide the Netherlands with the possibility to meet the EU threshold level for groundwater, without having to implement major additional measures by farmers. Nitrate concentrations are likely to decrease with depth because of denitrification. Any adjustment in the compliance checking level requires well-founded data on whether nitrate concentrations actually decrease with depth in the upper five meters of the groundwater. It must also be clear which processes cause the decrease, and in particular whether such an adjustment would result in a shifting of the problems to the surface water. The Nitrates Directive also has targets for surface water quality. A study showed that in sandy soils with relatively deep groundwater tables (i.e. > 1 meter) nitrate concentrations did not decrease with depth in the upper five meters of groundwater. Here, the act of denitrification may be blurred by temporal changes in nitrate leaching from the soil. In sandy soils with high and intermediate groundwater tables (within 1 meter) a decrease in nitrate concentrations with depth was shown. Results indicated that in these soils significant loads of agricultural nitrate are transported into surface waters. Thus, allowing higher nitrate concentrations in the upper groundwater may cause eutrophication of surface waters. The Dutch Parliament introduced a motion in 2009 stating that maintaining the current compliance checking level in the upper one meter of groundwater would result in unfair competition for Dutch farmers. The Dutch Parliament requested the Government to calculate the decrease in nitrate with depth using models and to measure the nitrate concentrations not only in the upper one meter of groundwater, but in the upper second and upper fifth meter of groundwater as well. A new monitoring network to meet the Parliaments request is currently drafted.

The present invention relates to a resonator-type surface-acoustic-wave filter with reduced insertion loss. The resonator-type surface-acoustic-wave filters (referred to below as resonator-type SAW filters) considered in the present invention have the well-known ladder circuit configuration. The ladder configuration does not require a matching circuit, and has such further advantages as low loss, high attenuation, and narrow bandwidth, but there is a trade-off between loss and attenuation. If the ladder configuration contains only one stage, or a small number of stages, insertion loss is low but attenuation in the stopbands may be inadequate. With a large number of stages, stopband attenuation improves but insertion loss increases, and the filter becomes large in size. A known solution to this problem couples one or more additional SAW resonators in series with the ladder circuit to improve the stopband attenuation. The present invention addresses this problem in the upper stopband, so the conventional solution would be to provide an additional SAW resonator with frequency characteristics adapted to improve the attenuation in that stopband. This solution is unsatisfactory in the following respects. First, the additional SAW resonator increases the insertion loss to some extent. Second, impedance matching characteristics are worsened, because the resonant frequency of the additional SAW resonator lies above the passband of the filter. (This is because the antiresonant frequency of the additional SAW resonator must be higher than the antiresonant frequency of the SAW resonator or resonators in the series arm of the filter.) Third, the additional SAW resonator increases the size of the filter.

The present invention relates to a rotary die cutter for blanking corrugated fiberboard sheets or the like. As a rotary die cutter of this type, a cutter, for example, shown in FIGS. 4 to 6 has been publicly known. In this cutter shown in FIG. 4, frames 1 are erected on both sides, right and left, and a die cut cylinder 3 and an anvil cylinder 4 are rotatably supported on these frames 1 via bearings 5. The die cut cylinder 3 has a cylindrical outer peripheral surface, and at opposite ends thereof are provided support shafts 3a coaxially. Each of the support shafts 3a is rotatably supported on the frame 1 via the bearing 5. Similarly, the anvil cylinder 4 also has a cylindrical outer peripheral surface, and at opposite ends thereof are provided support shafts 4a coaxially. Each of the support shafts 4a is rotatably supported on the frame 1 via the bearing 5. At a portion where each support shaft 3a protrudes from the frame 1, a gear 6 is provided to cause the die cut cylinder 3 to rotate. Also, at a portion where each support shaft 4a protrudes from the frame 1, a gear 7 is provided to cause the anvil cylinder 4 to rotate. These gears 6 and 7 mesh with each other. Each frame 1 is provided with a side cover 8 for covering the gears 6 and 7. This side cover 8 is constructed such that a portion under the gears 6 and 7 (a portion under the bearings 5) forms an oil reservoir 8a for storing a lubricating oil. The lubricating oil stored in the oil reservoir 8a adheres to a gear 10 supported rotatably on the frame 1, and further adheres to the gear 7 meshing with the gear 10, so that the gears 7 and 6 are lubricated. The bearing 5 is lubricated by grease loaded inside. As shown in FIG. 6, a blanking section itself is constructed so that the rotation is transmitted from, for example, a printing unit (not shown) on the upstream side by a connection gear 13 meshing with the gear 6, and is further transmitted to a unit (not shown) on the downstream side by a connection gear 14 meshing with the gear 6. As shown in FIGS. 4 and 5, a blanking die 11 is installed on the die cut cylinder 3, and this blanking die 11 is provided with knives 11a. The knife 11a performs blanking of a corrugated fiberboard sheet 12 by holding the corrugated fiberboard sheet 12 between the knife 11a and the surface of the anvil cylinder 4. The rotary die cutters come in two types: a cutting type called soft cut in which a sawtooth knife is used as the knife 11a and a rubber anvil is used as the anvil cylinder 4, and a cutting type called hard cut in which a straight tooth knife is used as the knife 11a and a metal anvil is used as the anvil cylinder 4. In the case of the latter hard cut, since cutting is performed by pressing the hard knife 11a on the hard anvil cylinder 4, the pressing amount, in other words, a center distance between the die cut cylinder 3 and the anvil cylinder 4 is required to be maintained precisely (usually, an accuracy in the order of 1/100 mm is strictly kept). If such a center distance cannot be kept, an uncut portion remains on the corrugated fiberboard sheet 12, or the blade edge of the knife 11a is collapsed by an excessive pressure. In the above-described rotary die cutter, the bearings 5 are heated by the rotation of the die cut cylinder 3 and the anvil cylinder 4, and part of this heat is transmitted to the frames 1, so that the temperature of the frames 1 rises. Therefore, the frame 1 is elongated by thermal expansion, resulting in an increase in the distance between the support shafts 3a and 4a of the die cut cylinder 3 and the anvil cylinder 4. For this reason, a cutting pressure of the knife 11a acting on the anvil cylinder 4 decreases, or sometimes a gap is produced between the knife 11a and the anvil cylinder 4, which leads to a possibility that improper cutting occurs. To overcome this problem, with the elapse of time, it is necessary to adjust the aforesaid distance between the support shafts 3a and 4a, or to adjust the blanking die 11, which causes the hindrance to productivity. Also, part of the aforesaid heat is transmitted to the die cut cylinder 3 and the anvil cylinder 4 via the support shafts 3a and 4a, respectively, by which the temperature of the cylinders 3 and 4 are also increased. At this time, after the support shafts 3a and 4a first becomes hot, the heat conducts gradually from both the ends toward the central portion of the cylinders 3 and 4. That is to say, in each cylinder 3, 4, a temperature gradient is created from both the ends to the central portion. Thus, as indicated by the dashed line in FIG. 4, each cylinder 3, 4 is thermally deformed into a concave form. In this case, a gap between the knife 11a and the anvil cylinder 4 is narrow at portions at both ends of each cylinder 3, 4, and a gap between the knife 11a and the anvil cylinder 4 is wide at the central portion thereof, so that the cutting conditions becomes nonuniform in the width direction. Further, since the amount of temperature rises of the frames 1 and the cylinders 3 and 4 are not equal, there is a difference between the change amount of center distance between the cylinders 3 and 4 caused by the thermal expansion of the frames 1 and the change amount (average amount in the width direction) of outside diameter of each cylinder 3, 4 caused by the thermal expansion of each cylinder 3, 4 itself. Therefore, with the elapse of operation time, the pressing pressure (average pressure in the width direction) of the knife 11a on the anvil cylinder 4 changes undesirably, which also makes the cutting conditions nonuniform.

Closed chains, chain nets, snow chains, protective tire chains, and other chain systems are not adjustable in terms of length and width (in the case of grid or ladder chains) unless the chain is opened and/or individual chain links are opened in order to remove or add chain links. The same applies for jewelry chains. Many variants for connecting the last links in a finite chain by way of a special connecting element are also known in the art. Such a connection becomes necessary most frequently when chains break; for example, breaks on snow chains of motor vehicles or on protective tire chains of utility vehicles operating in stone quarries and similar environments. The problem that emerges when two ends of a broken chain must be connected is the fact that, most of the time, no suitable tools are available on site where the break occurred in order to install a regular chain link that was cut open for that purpose and must be welded closed again after having been inserted. Welding on the wheel is generally not possible because this may cause damage to the tire. Any removal of the chain armor from protective chains is extremely complex and creates, moreover, costs associated with the disruption of operations during the disassembly, repair work, and new installation. Accordingly, repair chain links are already known in the prior art that can be connected to the links of the broken chain right on the vehicle. The repair chain links are often comprised of a ring with an overlapping thread that extends over a certain area in the way of a helical line. Chain links of this type can be inserted directly on the wheel into the outermost-lying chain links and then pressed together with the assistance of a strong pair of pliers. Also known are, furthermore, repair links that feature an (open) C-form; the only way to guide them around the neighboring chain links is with a pair of pliers, and then they must be bent in a backward direction. Reconnecting a broken chain without the use of tools is not possible with any of the known prior art repair links. Moreover, the repair links are usually only a short-term solution because, since they must be bendable after installation, they may not be manufactured of a hardened material. At a later time they must be replaced at a repair shop with other durable links. This requires additional expense.

A plating shop typically generates a waste stream that includes nickel, chromium, copper, zinc, cyanide, and other ions. Current technology for treating a waste stream from a plating shop generally involves separating the waste stream into alkaline, acid, chromate and cyanide waste streams. The cyanide stream is made strongly alkaline and is treated with a hypochlorite (bleach) to totally destroy the cyanide. The chromate containing stream is treated with metabisulfite or sulfur dioxide in order to reduce the hexavalent chromium to the trivalent state. Then all streams are combined and made strongly alkaline. This forces all the heavy metals to precipitate as oxides and hydroxides. Usually a flocculant is added to encourage full precipitation. At this point the precipitates can be filtered out of the combined waste stream. Then the stream is neutralized with an acid. The treatment system is complex, including many tanks; feed loops, under automatic control, for introducing reagents to these tanks; impellers or equivalent devices for adequate mixing of reagents with the waste streams; and at least one filter press for separating the water from the precipitated metals. Not infrequently, the whole system is under computer control. Plating wastes treated in this manner typically meet requirements for discharge into water courses and sanitary sewers. The sludges generated are generally trucked to a sanitary landfill. It can be readily appreciated that the system described above is large, costly, and requires massive quantities of chemicals for its operation. Further it is not readily amenable to treatment of acid mine waste and clean up of hazardous waste sites. The types of systems suitable for treating acid mine wastes, for recovering metals, and for removing heavy metals from the soil at hazardous waste sites vary considerably from the typical plating waste treatment system described above. Such systems are typically designed for each specific application and so no generalized design can be given. Development of a treatment system which can remove heavy metals and other harmful contaminants from plating waste streams, acid mine wastes and hazardous waste sites or recover valuable metals in a simple and economical manner represents a great improvement in the field of waste treatment and satisfies a long felt need of the waste treatment industry.

Kaposi's sarcoma in the pediatric population: the critical need for a tissue diagnosis. Kaposi's sarcoma (KS) is a low-grade vascular neoplasm mediated by the human herpesvirus-8. Only 1 clinical subtype, the endemic/African subtype, commonly affects the pediatric population. Although adults with KS often present with cutaneous findings and generalized lymphadenopathy, African children are more likely to present without classic skin findings. Definitive diagnosis requires histologic examination from tissue biopsy; however, as pathology resources are scarce in many developing African countries where KS is prominent, appropriate diagnosis and treatment of the condition are challenging. We report the case of a Malawian child who presented with generalized lymphadenopathy and was presumptively treated for lymphoma, with clinical worsening of his lesions. A diagnosis of KS was made after excisional biopsy of a superficial lymph node, with the initiation of appropriate therapy. The literature regarding pediatric KS is reviewed and recommendations are offered to allow accurate and timely diagnosis of the condition.

The enzymes responsible for repairing DNA damage also function in several biologically significant pathways such as DNA replication, genetic recombination, and mutation fixation; and are thus directly implicated in the oncogenic process. Not only is little known about the repair of ionizing radiation-induced damages in DNA, but the chemical nature of these damages remains to be elucidated. The proposed research would be undertaken in an effort to define the molecular mechanisms involved in the repair to X-ray-induced damages in DNA using T4 bacteriophage and its Escherichia coli host as model systems. To this end, the DNA synthetic patterns of the recombinational repair deficient T4 x and y mutants have been examined, and the existence of aberrant DNA replicative intermediates established. An attempt will be made to isolate the products of the x and y genes by a complementation assay. Further, the E. coli X-ray endonuclease will be purified, and its properties delineated. Lastly, irradiated phage DNA will be repaired in vitro by purified enzymes of known specificities, and assayed for biological activity by transformation or transfection.

Analysis of hemorrhagic risk factors during deep brain stimulation surgery for movement disorders: comparison of the circumferential paired and multiple electrode insertion methods. The most serious complication of deep brain stimulation (DBS) surgery is intracranial hemorrhage. The authors have assessed risk factors for hemorrhage in DBS surgery and compared two types of microelectrode insertion technique on hemorrhagic risk. A total of 171 DBS procedures were performed on 110 patients (58 females, 52 males) by the same neurosurgeon at a single center between May 2005 and May 2010. We used two microelectrode insertion methods: multiple microelectrode insertion (MMI) and circumferential paired microelectrode insertion (CPMI). We analyzed the correlation between bleeding rates and gender, age, hypertension, target location, simultaneous bilateral procedure and electrode insertion method. Of the 171 DBS procedures, 138 were on 85 patients with Parkinson's disease, 16 were in 15 patients with essential tremor and 17 were on ten patients with dystonia. There were nine postoperative hemorrhagic events (5.26%), of which three were symptomatic (1.75%), and one permanent neurological deficit event (0.58%). Compared with the bleeding rate in the MMI method (9/106, 8.5%), there was no instance of bleeding with the CPMI method (0/65, 0%) (p = 0.04). In other factors, the correlation with hemorrhage was not found. Use of the CPMI method significantly decreased the rate of bleeding. This new surgical technique seems to be safe and accurate and may be recommended as another surgical option.

Towards an understanding of how appraisal of doctors produces its effects: a realist review. Revalidation was launched in the UK to provide assurances to the public that doctors are up to date and fit to practice. Appraisal is a fundamental component of revalidation. Approximately 150 000 doctors are appraised annually, costing an estimated £97 million over 10 years. There is little understanding of the theory of how and why appraisal is supposed to produce its effects. A realist review of the literature was utilised to explore these issues, as they generate context-mechanism-outcome (CMO) configurations, resulting in the creation of theories of how and why appraisal of doctors produces its effects. A programme theory of appraisal was created by convening stakeholders in appraisal and searching a database of research on appraisal of doctors. Supplementary searches provided literature on theories identified in the programme theory. Relevant sections of texts relating to the programme theory were extracted from included articles, coded in NVivo and synthesised using realist logic of analysis. A classification tool categorised the included articles' contributions to programme theory. One hundred and twenty-five articles were included. Three mechanisms were identified: dissonance, denial and self-affirmation. The dissonance mechanism is most likely to cause outcomes of reflection and insight. Important contexts for the dissonance mechanism include the appraiser being highly skilled, the appraisee's working environment being supportive and the appraisee having the right attitude. The denial mechanism is more likely to be enacted if the opposite of these contexts occurs and could lead to game-playing behaviour. A skilled appraiser was also important in triggering the self-affirmation mechanism, resulting in reflection and insight. The contexts, mechanisms and outcomes identified were, however, limited by a lack of evidence that could enable further refining of the CMO configurations. This review makes a significant contribution to our understanding of appraisal by identifying different ways that appraisal of doctors produces its effects. Further research will focus on testing the CMO configurations.

PRAC2: a new gene expressed in human prostate and prostate cancer. The database of human Expressed Sequence Tags was previously used to identify PRAC (Prostate 47:125-131, 2001), a novel gene specifically expressed in human prostate, prostate cancer, rectum, and distal colon. In this report, we have identified PRAC2, another gene with a similar expression pattern that is located adjacent to the original PRAC gene on chromosome 17q21.3. Using a computer-based analysis, a cluster of sequence homologous ESTs was identified that is mainly derived from human prostate cDNA libraries. The tissue specificity was examined by multiple tissue RNA dot blots and RT-PCR. The PRAC2 transcript and protein were identified using Northern blot analysis, RACE-PCR, primer extension, and Western blots. PRAC2 encodes a 564 nucleotide RNA found in prostate, rectum, distal colon, and testis. Weak expression was also found in placenta, peripheral blood leukocytes, skin, and in two prostate cancer cell lines: LNCaP and PC-3. The transcript seems to encode a 10.5-kDa nuclear protein. The PRAC2 gene is located on chromosome 17 at position 17q21, between the Hoxb-13 gene and the recently discovered PRAC gene. Because of the higher expression of PRAC2 in prostate and its proximity to Hoxb-13, PRAC2 may have a function in prostate growth and development.

This invention generally relates to projection displays, and more specifically applies to dimming in projection displays. Various types of optical displays are commonly used in a wide variety of applications. Included among these various types of displays are projection displays. Projection displays typically involve optical relaying of the displayed image prior to viewing. A typical projection display system will often include a diffuse viewing screen. One of the attractive characteristics of many projection displays is the flexibility of configuring a system with the particular features needed for a specific application. One important performance parameter in certain projection displays is the range of luminance that can be provided by a projection display, commonly referred to as the dimming range. In many applications it is critical that a display make information clearly visible in a wide variety of ambient light conditions. For example, a display used in an avionics control system will need to display information to the pilot under lighting conditions that can range from near total blackness to the extreme glare created by facing directly into daytime sunlight. Such a display must have a high maximum dimming ratio, where the dimming ratio is the ratio of the display luminance at highest brightness to the display luminance at its current setting. Without a sufficiently high maximum dimming ratio, a viewer of the display may be unable to easily read information from the display in high ambient light conditions, low ambient light conditions, or both. In some applications, the required maximum dimming ratio may be as little as 100:1. In other applications, a maximum dimming ratio of 20,000:1 or greater may be required to effectively display information in its expected range of ambient conditions. It should also be noted that in some applications alternative measures of light output may be used rather than luminance. In these cases, the dimming ratio can be expressed with respect to that measure. One such example might be the amount of optical power within a certain wavelength band. Additionally, in some applications the ability to precisely control the amount of dimming is of particular importance. This is typically of greatest concern in low light conditions, where small changes in the amount of dimming can have significant effects on the viewability of the display. Unfortunately, many prior dimming solutions have been unable to provide the precise dimming control needed for many critical applications. Thus, in many applications the projection display must be able to accurately and clearly display information through a wide dimming range, with the ability to precisely control the amount of dimming. Unfortunately, prior art solutions to dimming in projection displays have met with limited success. As mentioned above, some prior art solutions have been unable to reliably achieve the wide dimming range or the precise dimming control needed for certain critical applications. Other prior art solutions have required excessively complex structures that require large amounts of space and suffered from high cost and low reliability. Some prior art solutions have also negatively impacted the high bright state luminance required for bright ambient conditions. Thus, what is needed is an improved dimming system that provides a wide dimming range and precise control over the amount of dimming in a projection display. The present invention provides a dimming system that facilitates a wide dimming range and precise control of the dimming range. In one embodiment, the dimming system comprises a multi-aperture dimming system. The multi-aperture dimming system can be implemented in any display that utilizes a fly""s eye lens array. The multi-aperture dimming system comprises a plurality of moveable attenuators. The moveable attenuators are configured to form a plurality of apertures that can be controllably opened and closed. Each of the plurality of apertures attenuates a portion of the light propagating through at least one of the lenses in the fly""s eye lens array. Thus, by selectively controlling the plurality of moveable attenuators, the dimming system can control the throughput of light propagating through the fly""s eye lens array, where the throughput is the percentage of light passed compared to the light passed at maximum brightness and thus is the reciprocal of the dimming ratio at a given setting. The moveable attenuators are preferably configured to allow substantially all light transmission through each lens in the fly""s eye lens array when the moveable attenuators are moved to open the plurality of apertures. Likewise, the plurality of moveable attenuators are preferably configured to block substantially all light through each lens in the fly""s eye lens array when moved to close the plurality of apertures. Thus, the dimming system can provide a wide range of throughputs and dimming ratios. In a further variation on this embodiment, the moveable attenuators each have an attenuation profile at the area forming each of the plurality of apertures to increase the control over the dimming system at low light transmission levels The attenuation profile increases the dimming control by increasing the ratio of moveable attenuator movement to the corresponding change in throughput at low light transmission levels where the apertures are small and the dimming ratio is high This improves dimming control by making throughput change less sensitive to attenuator movement at these low light levels. In addition, the attenuation profile can be implemented to provide a plurality of sequential dimming modes, where each dimming mode provides a different ratio of attenuator movement to throughput change. The foregoing and other objects, features and advantages of the invention will be apparent from the following more particular description of a preferred embodiment of the invention, as illustrated in the accompanying drawings.

Fricatives at 18 months as a measure for predicting vocabulary and grammar at 24 and 30 months. Language develops at variable rates in young children, yet markers for different developmental trajectories, have not been identified. Production of fricatives in words may be one marker because they are later developing sounds and contribute to syntactic production. We examined whether children who produced fricatives in words by 18 months had better vocabulary and grammar scores at 18, 24, and 30 months than children who did not. The expressive language skills of 37 toddlers who did and did not produce fricatives in words by 18 months of age were compared at 18, 24 and 30 months of age. Expressive vocabulary scores and the use of grammatical markers were significantly better for children who produced fricatives by 18 months than for those who did not. This effect was consistent across scores at 18, 24, and 30 months. The total number of consonants and total number of fricatives produced at 18 months did not significantly predict expressive vocabulary scores. Because the children who produced fricatives by 18 months demonstrated better expressive language skills than their peers who did not produce fricatives by 18 months, the early production of fricatives by toddlers may be a marker of a faster expressive language developmental trajectory. Readers will: (1) describe the relationship between early phonological development and early expressive lexical development, (2) describe the role of perceptual and motor development in speech sound the acquisition, and (3) describe the potential relationship between the production of fricatives and expressive language development.

The invention relates to a rotatable motor vehicle mirror of a type, e.g., depicted and described in German Patent application (OS) No. 2,415,407 counterpart to U.S. Pat. No. 3,942,863. The rotatable motor vehicle mirror type noted above has suction passages in the form of air guiding grooves in the bordering region between the shaft and the inside of the rotor bearing bore. Although the resulting air bearing and the air flow aspirated by the fan through the air guiding groove dissipates the bearing heat produced by friction and utilizes it to heat up the mirror, the bearing may overheat at high vehicle speeds or high speeds of rotor rotation. This risk can be largely excluded by the use of suitable materials for the bearing, but this in turn increases the manufacturing costs, particularly on account of the installation of bearing sleeves. It is the object of the present invention to provide a rotatable mirror for motor vehicles which, despite simple construction of the rotor bearing, largely permits the utilization of the bearing heat to heat up the mirror, and which causes little noise during operation. The advantages attainable by the invention especially reside in the fact that the relatively high resistance offered by the suction passageways to the oncoming air causes subatmospheric pressure at their outlet ends which aspirates additional air through the bearing clearance so that an air cushion builds up in the bearing clearance which results in low-friction and low-noise operation of the rotor. Owing to this air cushion, there is no need to use expensive bearing materials, and a plastic bearing may be employed. At the same time the air flow in the bearing clearance dissipates a substantial portion of the generated bearing heat at the place where it develops. In addition, a plurality of suction bores provided a small distance from the bearing bore contribute to the uniform dissipation of the bearing heat. Furthermore, the characterized inclined position of the blades prevents the development of noise.

The present invention relates generally to heat exchangers and more particularly to a method of transferring heat from primary fluid to secondary fluid utilizing a particularly designed heat exchanger which is especially suitable for transferring heat from primary liquid metal to secondary liquid metal, for example liquid sodium, for cooling a fast breeder nuclear reactor or the like. A liquid metal cooled fast breeder reactor power plant typically uses what is commonly referred to as an intermediate heat exchanger for transferring heat from liquid metal primary coolant, which becomes radioactive while cooling the reactor core, to an isolated intermediate or secondary circuit of liquid metal which does not become radioactive to any significant extent. In most cases, the heat transferred to the intermediate or secondary stream is not wasted but rather used, for example, to make steam for driving a turbine-generator. To date, there have been a number of problems associated with power plants of the type just mentioned. For example, the conventional heat exchanger utilized heretofore has typically displayed a relatively high pressure drop, for example 10 psi or more, across its primary liquid metal side. This in turn means that the primary circulation pump must be placed in the "hot leg" of the overall primary circulation loop, that is, the pump must be located in the section of the loop from the reactor to the heat exchanger rather than in the "cold leg" after the heat exchanger. This is mainly due to the net positive suction head requirements of such pumps and specifically because they tend to cavitate if operated at too low a net positive suction head. However, placing the primary circulation pump in the hot leg is undesirable because of being subjected to very severe operating requirements including thermal transients and high temperature, for example temperatures as high as 1050.degree. F. In fact, where pumps of this type are to be used in commercial sized reactors, it may be entirely impractical to design them with a capability to withstand the severe operating requirements under hot leg conditions. Proposals have been made to place the primary circulation pump in the cold leg of the primary loop by obtaining a net positive suction head sufficient to overcome the pressure drop of the heat exchanger. This has been attempted by pressurizing the cover gas over the primary liquid metal in the reactor vessel, which metal is typically sodium, and also by lengthening the pump shaft, that is, lowering the pump inlet relative to the sodium level in the reactor vessel. However, pressurizing the cover gas is undesirable because it could be hazardous if the pressure were lost during a transient period. Moreover, the longer shaft is undesirable because of bearing problems. Still another proposal has been to reduce the pressure drop by enlarging the overall size of the heat exchanger and specifically by making its ratio of volume to heat transfer surface quite high. However, because space is at a premium with regard to fast breeder reactors, this solution would be quite costly and, in some cases, economically prohibitive. As will be seen hereinafter, the heat exchanger designed in accordance with the present invention eliminates the various drawbacks just discussed. More specifically, this heat exchanger displays a sufficiently low pressure drop across its primary side so that the primary circulation pump can be located in the cold leg of the primary circulation loop. Moreover, this is accomplished in an uncomplicated and economical way without pressurizing the cover gas over the primary sodium in the reactor vessel, without lengthening the pump shaft and without enlarging the overall exchanger.

Integrated development environments (IDEs) provide a common platform and design tools for modern software development. While software is often the most time-consuming and highest risk aspect of electronic program development, it also holds the greatest potential to enhance a design for multiple target applications. Such design tools allow designers to efficiently develop code where graphical user interfaces (GUI) automate and simplify configuration of complex programming projects. These tools also enable designers to create source code by enhancing code readability and simplifying code writing. For instance, source code editor features may include syntax coloring, auto-indenting and shortcut menus that link stored procedure calls to their definitions, declarations and usages even when these references reside in separate files. Other aspects of the tools include simulation resources to allow designers to develop and debug applications. One area of software development that is performed on IDEs includes mapping class objects to relational objects, referred to as O/R mapping, and is the latest advancement in modern day programming technologies. It improves productivity of programmers by many degrees while providing flexibility to adapt to changing business needs. While O/R technology itself provides many benefits to programmers, enabling O/R classes to be created and set up correctly is not an easy task for normal development nor is it well supported in current programming tools. Without providing adequate tools support, programmers trying to adopt the technology may be forced to write their respective code manually. One purpose driving O/R technologies is the need to interface the relational database world with the models supported in the object oriented programming world. For example, relational database management systems (RDBMS) supporting a relational database pre-dated the popularization of object-oriented programming in the 1990s. Using relational databases to store object-oriented data leads to a semantic gap where programmers would be required to allow their software to function in two different worlds—processing of data would be performed in object-oriented form, but the same data would have to be stored in relational form. Requiring this constant conversion between two different forms of the same data not only had the effect of stifling performance but also imposed difficulties for programmers as relational or object-oriented forms would impose limitations on each other. For example, relational databases make complicated associations difficult, and they tend to “map” poorly into the object-oriented world since they fail to implement the relational model's user-defined types. This problem is sometimes referred to as the Object-Relational impedance mismatch. Generally, relational databases use a series of tables representing simple data, where optional or related information is stored in other tables. A single (persistent object) record in the database often spans several of these tables, and requires a join to collect all of the related information back into a single piece of data for processing. This would be the case for an address book example, which would likely include at least a user and address table, but perhaps even a phone number table as well. In the object world, there is a clear sense of “ownership,” where a particular person object owns a particular phone number in the above example. This is not the case in relational databases, where the tables have no understanding how they relate to other tables at a fundamental level. Instead, the user must construct a “query” to gather information together. Queries not only request what information to return but also need to know how the tables involved are related to each other, illustrating the point that tables do not know their relationships when they are residing in the database. Thus, these relationships are typically only known when a query is run to specify the relationships. Relational databases (which attempt to implement the Relational Model), do maintain relationships via constraints but the Structured Query Language (SQL), for example, is generally unaware of these. When creating Object/Relational (O/R) classes by mapping class objects to database objects, it is important to also set correct associations between related objects so that applications written on top of these objects can easily take advantage of such relationships. Hand coding such relationship is not a trivial task for typical developers. While the O/R technology itself provides many benefits to programmers, manually having O/R classes created and set up correctly is not a straightforward or simple task. With current development tools support, programmers trying to adopt O/R technology are often forced to write code manually which detracts from the utility of such tools.

Comparing air dispersion model predictions with measured concentrations of VOCs in urban communities. Air concentrations of nine volatile organic compounds were measured over 48-h periods at 23 locations in three communities in the Minneapolis-St. Paul metropolitan area. Concentrations at the same times and locations were modeled using a standard regulatory air dispersion model (ISCST3). The goal of the study was to evaluate model performance by comparing predictions with measurements using linear regression and estimates of bias. The modeling, done with mobile and area source emissions resolved to the census tract level and characterized as model area sources, represents an improvement over large-scale airtoxics modeling analyses done to date. Despite the resolved spatial scale, the model did not fully capture the spatial resolution in concentrations in an area with a sharp gradient in emissions. In a census tract with a major highway at one end of the tract (i.e., uneven distribution of emissions within the tract), model predictions atthe opposite end of the tract overestimated measured concentrations. This shortcoming was seen for pollutants emitted mainly by mobile sources (benzene, ethylbenzene, toluene, and xylenes). We suggest that major highways would be better characterized as line sources. The model also failed to fully capture the temporal variability in concentrations, which was expected since the emissions inventory comprised annual average values. Based on our evaluation metrics, model performance was best for pollutants emitted mainly from mobile sources and poorest for pollutants emitted mainlyfrom area sources. Important sources of error appeared to be the source characterization (especially location) and emissions quantification. We expect that enhancements in the emissions inventory would give the greatest improvement in results. As anticipated for a Gaussian plume model, performance was dramatically better when compared to measurements that were not matched in space or time. Despite the limitations of our analysis, we found thatthe regulatory air dispersion model was generally able to predict space and time matched 48-h average ambient concentrations of VOC species within a factor of 2 on average, results that meet regulatory model acceptance criteria.

Prepare for every stage of your physician assistant career with Physician Assistant: A Guide to Clinical Practice, 5th Edition - the one text that takes you from your PA coursework through clinical practice! Concise, easy to read, and highly visual, this all-in-one resource by Ruth Ballweg, Edward M. Sullivan, Darwin Brown, and Daniel Vetrosky delivers the current, practical guidance you need to know to succeed in any setting. New to this edition Navigate today's professional challenges with new chapters on NCCPA Specialty Recognition; Communication Issues; the Electronic Health Record; Patient Safety and Quality of Care; Population-Based Practice; and Physician Assistants and Supervision. Meet ARC-PA accreditation requirements with coverage of key topics such as Student Safety in Clinical Settings, Health Care Delivery Systems, Population-Based Practice, and Mass Casualties/Disasters. Keep up with the PA competencies that are endorsed by the AAPA, PAEA, NCCPA, and ARC-PA. Master key concepts and clinical applications thanks to a succinct, bulleted writing style; convenient tables; practical case studies; and clinical application questions throughout. Retain what you've learned and easily visualize every aspect of clinical practice with a new full-color design and illustrations throughout. Explore global options with expanded coverage of physician assistants in international medicine.

7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens. Mesolimbic dopaminergic system activation correlates with ingestive behavior in numerous feeding regimens. DA release is enhanced by food intake following deprivation, amount of food consumed, and the palatability of the food consumed. The dopamine-3 receptor (D3-R) has a limited expression pattern that is restricted largely to the mesolimbic dopaminergic system. The D3-R has been hypothesized to inhibit DA-mediated reward, locomotion and motivation. To test the potential for an inhibitory role of the D3-R on food intake, we administered the D3-R agonist 7-OH-DPAT (5, 10 and 50 microg/kg ip) to rats that had ad libitum access to standard rodent chow (3.41 kcal/gm, 0.51 kcal/gm from fat) or a preferable, high fat (HF) (4.4 kcal/gm, 1.71 kcal/gm from fat). In the second set of experiments we administered 7-OH-DPAT (10, 50 and 100 microg/kg) to rats that had access to chow or HF diet for only 3 h per day (meal fed). In the third set of experiments we administered 7-OH-DPAT (10 and 50 microg/kg) to rats that had access to chow or HF diet after a 21-h food restriction. The 10 and 50 microg/kg doses significantly, but equally reduced intake of chow and HF diet in animals that were ad libitum fed. In animals that were meal-fed the dose response was effectively shifted to the right and the 10 microg/kg dose was ineffective at reducing intake. The 50 and 100 microg/kg doses significantly but equally reduced intake of both diets. In animals that were 21-h restricted and had access to chow both the 10 and 50 microg/kg doses were ineffective at reducing intake. However, in animals that had access to HF diet, 7-OH-DPAT dose-dependently reduced intake. These results support a potential role for the D3-R in ingestive behavior particularly in situations that involve a significant learned component.

Down-regulation of urinary AQP2 and unaffected response to hypertonic saline after 24 hours of fasting in humans. In rats, 24 hours of fasting impairs urinary concentrating ability by down-regulation of aquaporin-2 (AQP2). We tested the hypothesis that 24 hours of fasting in humans reduces the capability to form AQP2 and impairs the antidiuretic response to hypertonic saline infusion. In a crossover study of 14 healthy subjects, the effect of 24 hours of fasting was compared to a nonfasting control experiment on urinary excretion of AQP2 (u-AQP2), free water clearance (C(H(2)O)), plasma arginine vasopressin (AVP), urinary cyclic AMP (u-cAMP), and natriuretic peptides. The following response to 3% sodium infusion was measured using the same effect variables. U-AQP2, AVP, and u-cAMP were determined by radioimmunoassays. Fasting during 24 hours reduced u-AQP2 (14%), increased AVP (30%) despite a reduction in serum osmolality (P < 0.05), and depleted volume. C(H(2)O) and urine volume were not reduced, thus relatively increased after fasting. u-cAMP was not significantly different between the two procedures. Three percent saline resulted in the same relative increases in AVP, serum osmolality, u-AQP2, and u-cAMP and decreases in C(H(2)O) and urine volume independently of fasting. The reduced u-AQP2 and increased AVP after fasting were maintained during and after saline infusion. Twenty-four hours of fasting decreased u-AQP2 and reduced urine osmolality likely as a result of decreased sensitivity of collecting duct cells to AVP. Fasting-related insensitivity of collecting duct cells to AVP was restored by 3% saline infusion. Finally, after saline infusion, other factors such as the increased plasma atrial natriuretic peptide (p-ANP) levels could contribute to the u-AQP2 regulation.

1. Field of the Invention This invention relates to liquid metering devices for use in metering the flow of viscous fluids and is more particularly concerned with devices for metering the flow of ink being fed under pressure from a storage vessel to a printing press. 2. Description of the Prior Art Fluid flow meters are well-known in the art and have been widely used to measure flow of liquids such as water, oil, fuels, hydraulic fluids and the like. Such meters include glass tube variable area meters, turbine meters, ultrasonic meters, coriolis effect meters and the like. However, such meters are generally unsatisfactory for use in metering the flow of relatively viscous materials such as printing inks which generally have viscosities in the range of about 100 to 200 poise. Main U.S. Pat. 4,042,149 describes a liquid pump and metering system for use with hot asphalt, a relatively viscous material which is difficult to handle. The system employs a first positive displacement pump which is responsible for pumping fluid within the system and a second positive displacement pump through which the fluid is pumped in a direction which is the reverse of that in which the second pump would normally operate. The second pump acts as a metering device the rate of rotation of the rotatable portion of the pump being a measure of liquid flow therethrough. The rate of rotation in question is sensed by a device mounted on the exterior of the pump shaft and signals generated by the device are processed by electronic means to determine rate of fluid flow. Krygeris U.S. Pat. 3,835,777 discloses a method of controlling ink supply to a printing press by employing sensors to monitor the density of ink being deposited on the material being printed. Signals generated by the sensors are compared with signals representing upper and lower limits of range of the desired density and control signals are derived to correct any deviation from the desired range. Rodvelt U.S. Pat. 4,524,692 teaches controlling the amount of ink transferred to the ink train in a printing press. The system includes a fountain roller in contact with the ink supply and a ductor roller which can be moved between the ink train and fountain roller. The control mechanism involves sensing the interval of rotational movement of the fountain roller when in contact with the ductor roller as a measure of the amount of ink transferred to the ink train. Fluid metering systems not specifically directed to use with viscous fluids such as ink but employing various types of sensing devices for detecting flow rates are disclosed in U.S. Pats. 4,520,677; 3,780,579; 3,906,198; 4,120,032; and 4,413,264. It has now been found that the amount of relatively viscous fluids being supplied to a system, such as ink passing through feed lines such as those connecting a source of ink to a printing press, can be determined accurately and conveniently using a method and apparatus which will be described hereinbelow.

Electrical connectors of the type having a C-shaped body member having converging channels and a complementary wedge member have been known conventionally for many years and are disclosed, for example, in U.S. Pat. Nos. 1,801,277; 4,415,222; 4,606,264; 5,006,081; and 5,145,420; all of which are herein incorporated by reference. Basically, for these wedge type connectors, two uninsulated conductors are electrically and mechanically connected by being pressed into and against interior curved surfaces or channels provided in a C-shaped body member. The pressing is provided by a wedge being driven longitudinally into the C-shaped body member between the conductors. These known wedge connectors have been successfully used in the power utility industry for large diameter cable where the C-shaped body members are massive enough to exert a resilient, compressive force against the cables trapped in the channels of the C-shaped body members by the wedge. It is desirable to provide a wedge type connector which can provide the same compressive forces against the wire and the wedge, but using a lesser amount of material than the prior art wedge type connectors.

Randomized trial of stent placed above and across the sphincter of Oddi in malignant bile duct obstruction. Placement of stents above an intact sphincter of Oddi might prevent migration of bacteria and deposition of organic material into the stent. In patients with malignant obstructive jaundice prolongation of function time of the stent would be expected if it is placed above the sphincter of Oddi. Thirty-four patients were randomized to stent placement either above (n = 17) or across (n = 17) the sphincter of Oddi. Straight 10F gauge Teflon stents were used. The patients were evaluated clinically and biochemically at monthly intervals during follow-up. The median stent function time (i.e., the time from insertion of the stent until stent replacement, patient death, or study termination) were 110 days (25th to 75th percentiles, 61 to 320 days) for stents placed above the sphincter of Oddi and 126 days (25th to 75th percentiles, 89 to 175 days) for stents placed across the sphincter of Oddi (nonsignificant [NS]). Stent replacement rates were 58.8% (10 of 17) in patients with stents placed above the sphincter and 29.4% (5 of 17) in patients with stents placed across the sphincter (NS). Significantly more patients in the former group experienced stent migration (9 vs. 2, p = 0.026). The median time from stent insertion until replacement of the stents placed above and across the sphincter of Oddi were 82 days (25th to 75th percentiles, 31 to 185 days) and 89 days (25th to 75th percentiles, 13 to 150 days), respectively (NS). No significant difference in overall stent performance between the two groups was found, although more stents placed above the sphincter of Oddi migrated. The time until dysfunction of the stent might be increased if migration of stents placed inside the common bile duct could be avoided.

This invention relates to a disposable diaper for absorption and containment of excretion, and more particularly, to a disposable diaper having a three-dimensional section for receiving feces. Japanese Patent Application Disclosure No. 1993-305109 describes a disposable diaper in which a topsheet intended to come in contact with the wearer""s skin is formed in its central zone with an opening shaped to be relatively long as viewed in its longitudinal direction. The opening is provided along its peripheral edge with an elastic element adapted to be elastic in the longitudinal direction. Japanese Patent Application Disclosure No. 1996-322878 describes a disposable diaper in which a liquid-absorbent core is divided in a crotch region in longitudinally front and rear sections spaced from each other by a desired distance. In the space left between these two sections, a topsheet and a backsheet are jointed to each other and a pair of flaps extend transversely to cover the space. The diaper described in the Japanese Patent Application Disclosure No. 1993-305109 intends to ensure that excretion discharged on the diaper reliably flows into the opening. However, such intention can not necessarily be achieved when the excretion is in the form of loose passage because, even if discharged onto the crotch region or the rear waist region of the diaper, such loose passage may spread over the topsheet into the front waist region and soil the urinogenital organs. The diaper described in the Japanese Patent Application Disclosure No. 1996-322878 intends to prevent loose passage from flowing into the front waist region. However, it is impossible for this known diaper to confine such loose passage in the vicinity of the spot onto which the loose passage has been discharged. As a result, the loose passage may spread over the topsheet in the crotch and rear waist regions. An object of this invention is provide a disposable diaper that is designed so that body wastes discharged thereon is reliably prevented not only from flowing into the front waist region but also from flowing and/or spreading in the crotch and rear waist regions. According to this invention, there is provided a disposable diaper having a front waist region, a rear waist region and a crotch region therebetween, the diaper comprising: a liquid-permeable topsheet, a liquid-impermeable backsheet and a liquid-absorbent core therebetween; a pair of elasticized gasket cuffs longitudinally extending outward from transversely opposite side edges of the core; a pair of elasticized barrier cuffs longitudinally extending adjacent the gasket cuffs on an upper surface of the diaper; and a feces receiving section extending at least partially across the crotch and the rear waist regions between the barrier cuffs, wherein the feces receiving section is defined by a pair of elasticized first barrier flaps transversely opposed to and spaced from each other and extending longitudinally of the diaper and a pair of elasticized second barrier flaps longitudinally opposed to and spaced each other and extending transversely between the first barrier flaps and connecting to the first barrier flaps.

As a lens for current bifocal eyeglasses, a progressive lens is widely known. The progressive lens is also referred to as “no-line bifocal lens”, where a far-vision region for looking at something in the distance, a near-vision region for looking at something near (presbyopia part), and an intermediate region are disposed in one lens. The intermediate region is a region in which, from diopter power (hereafter referred to as eyeglass degree) of the far-vision region to the eyeglass degree of the near-vision region, the eyeglass degree is progressively changed. For example, refractive power is changed by a method disclosed in Patent Document 1. Patent Document 1: JP-A-09-159976 In these progressive lenses, the eyeglass degree changes in a non-step manner from the far to the near, thereby providing an advantage in that any distance can be focussed with one lens. Also, since there is no boundary in the outer appearance, a so-called sense of agedness is absent, so that it is excellent in fashion property.

The effect of fentanyl anesthesia and intrathecal naloxone on neurologic outcome following spinal cord injury in the rat. Whereas opiate receptor agonists have resulted in spinal cord damage; opiate receptor antagonists have demonstrated protection against spinal cord injury. Because opioids are used in clinical anesthesia, the effect of an opiate antagonist was evaluated on neurologic outcome in a rat model of spinal cord injury occurring during opioid anesthesia. One day prior to spinal cord injury, a catheter was inserted into the spinal subarachnoid space with the tip at T8. On the day of spinal cord injury a balloon tipped catheter was inserted in the epidural space with the tip at the thoracolumbar junction. Spinal cord injury was produced by balloon inflation during one of the following states: 1) group 1 (A/S), injury was produced in awake rats and saline was administered in the subarachnoid space immediately following injury; 2) group 2 (F/S), injury was produced during a fentanyl/nitrous oxide (N2O) anesthetic, and subarachnoid saline administered; and 3) group 3 (F/Nx), injury was produced during a fentanyl/N2O anesthetic, and subarachnoid naloxone (1 mg/kg) was administered immediately following injury. Dose-response curves describing the relationship between the duration of balloon inflation and the percentage of animals with a persistent neurologic deficit were constructed and compared for differences by use of a group t test. The duration of balloon inflation required to produce a neurologic deficit was greater in both the F/S and F/Nx groups than in the A/S group (P less than 0.05). There was no difference between the F/S and F/Nx groups. In summary, in rats receiving a fentanyl/N2O anesthetic, neurologic outcome was improved compared with the awake state.(ABSTRACT TRUNCATED AT 250 WORDS)

Can serum cytokine profile discriminate irritant-induced and allergen-induced symptoms? A cross-sectional study in workers mostly exposed to laboratory animals. In workers exposed mostly to laboratory animals (LA), symptoms may be due to irritants or allergens. Correct aetiological diagnosis is important for health surveillance. This study aims to test whether work-related (WR) allergen-induced symptoms are associated with a cytokine profile distinct from that due to irritants. In a cross-sectional study (n=114), WR respiratory and/or skin symptoms were assessed through a standardised clinical examination and sensitisation to rat and/or mouse allergen determined by serum immunoglobulin E. Serum cytokine concentrations were measured by multiplex assays. The predefined cytokine profiles 'sensitiser' (interleukin (IL)-4, IL-5, IL-13, eotaxin-1) and 'irritation' (IL-8, IL-17A, IL-17F, IL-22) were considered positive, when ≥3 concentrations exceeded the 95th percentile of the asymptomatic non-sensitised group. Results were examined by hierarchical clustering analyses (HCA) and multiple linear regression. Explorative analyses were carried out for nine additional cytokines. Exposure to allergens and endotoxin was assessed in a subpopulation. The prevalence of the profile 'irritation' was comparable in 28 symptomatic non-sensitised workers and 71 asymptomatic non-sensitised workers. HCA showed that nearly all symptomatic non-sensitised workers were gathered in two subclusters, characterised by high IL-17A levels, but different IL-8 levels. Multiple linear regression identified drug consumption and current complaints as confounders. Sensitised subjects were too few (n=14) for testing the profile 'sensitiser'. In this unselected population of LA workers, the profile 'irritation' did not prove to be a valuable health surveillance tool. Low power precluded assessment of the profile 'sensitiser'. The increased IL-17A concentration may originate from irritative constituents of organic dust.

Changes in incidence of in situ and invasive breast cancer by histology type following mammography screening. To investigate secular trends and correlates of incidence of breast cancer by histology type following the introduction of population-based mammography screening. Analysis of age-standardised incidence rates for 1,423 in situ and 16,157 invasive carcinomas recorded on the South Australian population-based cancer registry for the 1985-2004 diagnostic period. Multiple logistic regression was undertaken to compare socio-demographic characteristics by histology. Progression from in situ disease was investigated using the Kaplan-Meier method. The incidence of in situ lesions increased approximately seven-fold over the 20-year period, compared with an increase of about 40% for invasive cancers. The increase for in situ lesions was due to increases for ductal carcinomas, with little change for lobular lesions. By comparison, the percentage increase in incidence for invasive cancer was greater for lobular than ductal cancers. Both for in situ and invasive cancers, percentage increases were greatest for the screening target age range of 50-69 years. One in 14 in situ cases was found to progress to invasive cancer within seven years of diagnosis, but insufficient detail was available to determine whether the invasive cancers were a progression of the in situ lesions or whether they originated separately. These invasive cancers were smaller than generally applying for other invasive cancers of the female breast. The larger secular increases in incidence for in situ than invasive cancers would reflect the dominant role of mammography in the detection of ductal carcinoma in situ. The lack of an increase for lobular in situ lesions may have resulted from their poorer radiological visibility. The greater percentage increase for lobular than ductal invasive lesions may have been due to an increase in imaging sensitivity for these lesions, plus real increases in incidence. The smaller sizes of invasive cancers found in women with a prior in situ diagnosis may have resulted from more intensive medical surveillance, although the possibility of biological differences cannot be discounted.

Digestive disease management in Japan: a report on the 6th diagnostic pathology summer fest in 2012. The 6th Diagnostic Pathology Summer Fest, held in Tokyo on August 25-26, 2012, opened its gates for everyone in the medical profession. Basic pathology training can contribute to the improvement of algorithms for diagnosis and treatment. The 6th Summer Fest with the theme 'Pathology and Clinical Treatment of Gastrointestinal Diseases' was held at the Ito International Research Center, The University of Tokyo. On August 25, 'Treatment of Early Gastrointestinal Cancer and New Guidelines' was discussed in the first session, followed by 'Biopsy Diagnosis of Digestive Tract: Key Points of Pathological Diagnosis for Inflammation and Their Clinical Significance' in the second session. On August 26, cases were discussed in the third session, and issues on pathological diagnosis and classification of neuroendorcrine tumor in the fourth session. The summaries of speeches and discussions are introduced along with the statements of each speaker. This meeting was not a formal evidence-based consensus conference, and 20 experts gave talks on their areas of specialty. Discussion was focused on how the management strategy should be standardized on the algorithm of patient care.

As disclosed by this inventor of the present invention in the U.S. Pat. No. 5,085,660, a vertebral fixation system comprises a double-threaded bone screw having a first threaded portion fro fastening onto a bone or vertebra, and a second threaded portion engageable with a fixation plate. The second threaded portion and the fixation plate are fastened at a right angle at which the first threaded portion is fastened onto a bone or vertebra. As a result, the angle at which the first threaded portion is fastened onto a bone or vertebra can not be changed in accordance with the surgical requirement when the fixation plate is chosen. Furthermore, the fixation plate is more rigid than the bone or vertebra onto which the double-threaded bone screw is fastened, thereby forcing the first threaded portion to fasten onto the bone or vertebra according to the advancing angle at which the second threaded portion is engaged with the fixation plate, if the angle at which the first threaded portion is fastened onto a bone or vertebra deviates from the advancing angle of the second threaded portion in the fixation plate. As a result, the threads formed by the first threaded portion in the bone or vertebra are vulnerable to damage and the first threaded portion of the double-threaded bone screw is therefore unable to hold the bone or vertebra securely.

1. Field of the Invention The invention relates to a foam dispenser including a housing and a fluid reservoir placed in the housing. The housing includes an opening, a plug connected to the fluid reservoir in the opening, and a foam pump. The foam pump includes an air pump, a fluid pump, a closable supply to the air pump, a nozzle, and a movable operating part and is configured to dispense a quantity of foam through the nozzle upon actuation of the operating part in a direction of pumping. The foam pump and the fluid reservoir are combined into a removable storage holder. The invention also relates to a housing for a foam dispenser configured to receive a removable fluid reservoir and a foam pump, and arranged for operation of the foam pump. Furthermore, the invention relates to a storage holder, e.g., for liquid soap, configured for placement in a foam dispenser and comprising a fluid reservoir having an opening, a plug connected to the fluid reservoir in the opening, and a foam pump. 2. Background of Related Art Soap dispensers with foam pumps can, in general, be divided into two categories. Certain variants are in use in hand soap dispensers, consisting of a flexible standing can. A foam pump is screwed into an opening at the top of the can with a nozzle pointing downwards and a dip tube that extends at least partly into the can. The pump is, therefore, located above the level of the fluid reservoir. The soap is pumped upwards. At the same time, air flows into the can via an air supply in the pump to prevent a vacuum from being established in the can. Such a soap dispenser must always be used standing up. If it is held upside down, soap flows through the air supply. There is also a chance of contamination from outside, which may block the air supply. For this reason, the pump and dispenser is not designed to last for a long period of time. In a different type of soap dispenser having a foam pump, the fluid reservoir is located above the level of the pump. This variant is especially suited for fitting in a bathroom or toilet. The fluid reservoir is used to store the liquid soap and is replaceable so that the foam dispenser can be recharged. In this variant, the pump is fixedly attached to the housing. For this reason, the pump is of a much more robust type. Because the fluid reservoir is located above the level of the pump, parts of the pump continually contact the fluid, due to gravitational effects, and can thus be harmfully affected. The pump must also last much longer, namely, as long as is needed to pump away the contents of a number of the replaceable fluid reservoirs. Replacement of the pump entails having to replace the entire housing and is, therefore, costly. PCT International Publication No. WO 95/26831 describes a fluid dispenser for dispensing foam. The device includes a collapsible fluid container and a foam pump attached to the container outlet. The foam pump includes two enclosures. The first enclosure is connected to the neck of the container and the second enclosure is telescopically received in the first. In an assembled state, the two enclosures define an air chamber and a fluid chamber, each having an outlet that join together at the foam outlet. The fluid dispenser includes a dispenser housing for detachably receiving the collapsible container and the foam pump. The foam pump may, therefore, be less robust, as the fluid reservoir and pump can both be replaced after use. A disadvantage of the known apparatus is that the foam pump has been designed especially for this application. The foam pump is only suitable for application in one sort of housing. This makes production of the pump much less economical, as it is manufactured in a small series, especially for this application. When one wants to make different versions of the housing and storage holder, for example, to provide dispensers for different types of fluid, different types of the pump and housing must be made, which further reduces the production series of both the pump and the housing and thus makes manufacturing less economical. Accordingly, there are needs for an alternative foam dispenser, housings for a foam dispenser, and storage holders which can be manufactured more easily and more efficiently.

Every year millions of small weights are attached to tires by automotive technicians balancing them. Tire balance, also referred to as tire unbalance or imbalance, describes the distribution of mass within an automobile tire and/or the wheel to which it is attached. When the tire rotates, asymmetries of mass cause the wheel to wobble. This wobbling can give rise to ride disturbances, usually vertical and lateral vibrations. It can also result in a wobbling of the steering. The ride disturbance due to unbalance usually increases with speed. Vehicle suspensions can be excited by tire unbalance forces when the speed of the wheel reaches a point that its rotating frequency equals the suspension's resonant frequency. Tires are inspected in factories and repair shops by two methods: static balancers and dynamic balancers. Tires with high unbalance forces are downgraded or rejected. When tires are fitted to wheels at the point of sale, they are measured again, and wheel weights, also known as correction weights, are applied to counteract the combined effect of the tire and wheel unbalance. Automotive technicians reduce the wobble to an acceptable level when balancing the wheel by adding small wheel weights to the inner and outer wheel rims. A wheel weight is installed by the use of a wheel weight and/or clip that secures the wheel weight to the edge of the wheel. A common garage tool, like a hammer, is typically used to hammer the wheel weight and/or clip down onto the wheel. To remove the wheel weight and/or clip another common garage tool, similar to a pair of pliers or a screw driver, are typically used to grasp and pinch or pry the wheel weight and/or clip to remove the wheel weight. Traditionally, wheel weights have been made of lead. However, to reduce environmental concerns, steel and zinc weights are being used more frequently. These steel and zinc weights are coated or non-coated. The coated weights have a coating on them which have been discovered to chip or scratch during the installation or removal of the wheel weight by standard wheel weight tools. In addition to the problem with the wheel weight chipping or scratching during installation and removal, the actual wheels themselves (or coatings on the wheels) have been discovered to chip and or scratch around its edges during installation or removal of the wheel weight with standard wheel weight tools. As should be understood these chipped and/or scratched portions of the wheel and/or wheel weights are undesirable for vehicle owners. It is thus highly desirable to create a wheel weight tool for installing and/or removing wheel weights that may be easier to use than common garage tools and may reduce or prevent chips and/or scratches on the wheel weight and/or wheel itself. The instant invention is designed to address the above mentioned problems.

In recent years, as disclosed in, for example, Japanese Patent Application Publication No. 2011-081539 (JP-2011-081539 A), the use of a calculation device that has a plurality of CPU cores mounted on a single semiconductor chip, namely, a multicore processor has been proposed in various fields. As disclosed in, for example, Japanese Patent Application Publication No. 2008-269487 (JP-2008-269487 A), the use of the multicore processor has been discussed in the field of the control of vehicular engines as well. The art disclosed in Japanese Patent Application Publication No. 2008-269487 (JP-2008-269487 A) is an art intended to reduce the consumption of electric power in the case where the multicore processor is employed in an engine control apparatus. According to this art, when a specific control processing is performed during the stop of engine control, the operation mode of a microcomputer is set to a low electric power consumption mode that is different from the operation mode during engine operation. In the low electric power consumption mode, the number of cores used by the microcomputer is made smaller than during engine operation. During the stop of engine control, no electric power is generated from an alternator or the like as during the operation of the engine, and an in-vehicle battery is not charged either. Therefore, the amount of consumption of electric power with which the battery is charged rapidly increases as the number of cores that operate during the performance of a specific control processing increases. One advantage of the use of the multicore processor is its high processing ability. Higher processing ability can be obtained from the multicore processor than from a single core processor having one CPU core. High processing ability is an inducement to employ the multicore processor in an engine control apparatus. This is because the number of actuators mounted on the engine and the number of types thereof have been on the constant increase in recent years. In order to appropriately control the operation of the engine, the control target values of actuators thereof need to be set to appropriate values corresponding to the operating condition of the engine. Therefore, an optimization calculation is performed in a conventional engine control apparatus, but the calculation load in performing the optimization calculation increases as the number of actuators and the number of types of actuators increase. Thus, it has been apprehended that the processing ability of the single core processor that is employed in the conventional engine control apparatus may eventually become insufficient for the ever-increasing calculation load. The use of the multicore processor has a great merit in the field of engine control in which the calculation load is estimated to constantly increase from here on. However, the processing ability of the multicore processor is not determined simply by the number of cores. In order to enhance the processing ability, a plurality of cores need to be efficiently operated. For this purpose, ingenuity has been demanded of the software that operates the cores. For example, tasks can be distributed to the plurality of the cores and processed in parallel in the multicore processor. However, the processing ability as a whole greatly differs on the method of parallelization.

Laser diodes present low impedance, of the order of a few ohms, whereas the external electrical feed lines used for conveying an electrical signal to a laser diode are generally of higher impedance, typically 50 ohms. In order to limit reflection losses on transmission of the signal from the external electrical feed line to the laser diode due to said different impedance values, it is necessary to match the impedance of the laser diode and of the external electrical feed line. Conventionally, such impedance matching has been performed by means of a connection device comprising a resistor deposited as a thin film on a substrate that also has the laser diode deposited thereon, said resistor being electrically connected in series between one of the conductors of the external electrical feed line and one of the electrodes of the laser diode. A bias T is also usually provided comprising a decoupling capacitor and an inductor for feeding the laser diode with bias current. The substrate, the resistor, the laser diode, and the bias T are usually mounted in a metal box that provides screening, that is provided with an external connector for connection to the external electrical feed line, and that is provided with a passage for receiving an optical fiber that is optically coupled to the laser diode. The box provided with the above-specified elements is called a "laser head". Nevertheless, a laser diode of that type does not provide full satisfaction since the resistor deposited as a thin film presents parasitic capacitance and inductance that distort the signal conveyed by the external electrical feed line, particularly when said signal is a binary signal at a very high data rate, typically greater than 10 Gbits/s. In addition, since the resistor is deposited on the substrate, it prevents distributed feedback (DFB) or distributed Bragg reflector (DBR) type laser diodes being mounted on the substrate since they are particularly sensitive to temperature, so local heating of the substrate due to electricity being dissipated in the thin film resistor would cause the operation of the laser to be unstable. Proposals have been made to mitigate those drawbacks by progressively changing the shape of the external electrical feed line so as to achieve continuous variation of impedance therealong until it matches the impedance of the laser diode. However, although such a solution eliminates problems of substrate heating, it gives rise to considerable radiation losses and it presents a narrow passband that is ill-suited to the frequency ranges covered by binary signals at high data rates.

Active immunotherapy to treat human cancer is one of the most rapidly developing fields in oncology. The Immune Monitoring Core Laboratory was established as a resource for investigators needing to monitor immunotherapy trials. The IMCL occupies 700 sq ft lab space with two adjacent 100 sq ft cell culture rooms in the new Center for Immunology Research (CCIR) facility. Created as a state-of-the-art facility, the goal of the lab is to work closely with each investigator at all stages of the clinical trial process by planning both the types of immune monitoring assays and number of data points suitable for each particular clinical trial, processing specimens, performing assays, and providing help with data interpretation. The IMCL also allows researchers to use dedicated equipment not usually available in individual labs. As part of this commitment to offer the most recent technology in immune monitoring to all researchers, the IMCL teams with industry and academic collaborators to develop new assays, to validate immune assays and to set rigorous quality control standards. The techniques used by the IMCL for immune monitoring include 1) cytokine ELISPOT assays;2) 6-color FACS phenotyping assays using HLA class I and class II peptide tetramers/multimers;3) intracellular cytokine staining methods;4) advanced ELISA-based technology that measures multiple cytokines in a single sample or reaction (multiplex cytokine analysis);5) newer T-cell proliferation assays using CFSE labeling coupled to FACS;6) more sensitive non-radioactive methods to determine antigenspecific CTL activity using FACS. The IMCL plays a key role in clinical trial development. During the previous funding period, IMCL services were used by 10 investigators from 8 of the 19 CCSG programs. 90 % of users had peer-reviewed funding and accounted for 80.7 % of utilization. Future plans are focused on Increasing the IMCL participation in CCSG-related clinical studies, as well as developing new assays to improve the amount and quality of information that can be obtained from a clinical trial.

The present invention relates to elevator systems. In particular, the present invention relates to power system for driving a plurality of elevator hoist motors. The power demands for operating elevators range from highly positive, in which externally generated power is used at a maximal rate, to negative, in which the load in the elevator drives the motor so it produces electricity as a generator. This use of the motor to produce electricity as a generator is commonly called regeneration. On average, if all the passengers who rise up through a building on an elevator also return down through the building on the same elevator, the average power required to run the system would be zero, but for frictional losses, electrical conversion losses, and power drawn by accessory equipment (e.g., lighting). However, this typically does not occur since most elevators are dispatched based on efficiency, and power management considerations are often ignored. For example, if two or more elevators are dispatched at the same time, the overlapping current transients from the associated motors results in a significant power demand on the power supply. Thus, the deliverable power from the power supply must be very large to avoid an overload condition if all elevators start at the same time. In addition, conventional multi-elevator power systems typically include a dedicated power bus and power converter for each hoist motor. Consequently, the power consumed by each hoist motor is independent of the power consumed by the other hoist motors of the multi-elevator power system. This results in inefficient use of the power supply. For example, a significant amount of energy generated by each of the hoist motors during regeneration may need to be dissipated as waste heat if negative power demands exceed the storage capacity of the power system. This not only is wasteful of the generated electricity, but also adds more waste in the requirement for air conditioning to keep excessive heating from occurring.

"Hi Frankie." "Hello." "Get in here." "Nothing like that first drink of the day" "Go on, drink up!" "Enjoy" "They tell me, you're quite a dancer?" "No?" "Well how about a dance anyway?" "Hey give them back." "What's the big idea?" "Frankie..." "Frankie, when did you get back?" "How are you?" "You all right?" "You know....." " The monkey is gone." " Let me look at you." " Not even a postie card." " You can't read anyway." " You're good at drawing pictures." "Oh, you goof-ball." "How's the lost dog business?" "As soon as they see me walking around, people start locking up their mutts." "I tell you folks just don't have that trust in their fellow man anymore." " Hey Antic, look who's out." " Frankie!" " You all right?" "Good kid." " Enough already, buy me a drink." " Look what the cat dragged in." " Frankie!" "You've been gone so long, I thought maybe you'd been made warden." " Well you're looking good." " Put on 6 pounds." "6 pounds!" "He's been gone so long, I thought maybe he'd been made warden." " How was it down there Frankie?" " Greatest place you've ever seen." "I'm telling ya, ball games, great food. I even learned how to play the drums." "You make it sound as if I missed something by not going to jail years ago. lt's a prison, no?" "More of a hospital kind." "Let me show you something." "Ah, Federal Pens is always best." "Ask anybody." "He's been gone so long, I think he's been made warden." "Ever see anything so pretty." " Don't touch!" " Hey, how'd you sneak them out Frankie?" " Them guys gave them to me in the band." "They let you have a band?" "Yeah, I was in it." "They chipped in and bought me these when I left." "Long time." "How was it there?" "Bad?" " lt wasn't bad." " Six months." "You could hardly wait, I bet?" " Come over to my place" " No thanks." "You broke?" "Now ain't you being stupid?" "It's for free." "I don't need it, that's all. I kicked it." "Oh, kicked it?" " One of them." " l mean it." "Sure I'll be around." "Frankie, don't do it." "Don't start up with that peddlar again." "I'd rather chop my arm off, before I'd let him touch it." "this Dr. Lennick who took care of me down at the hospital, real good guy he told me at least 10 times........" "He told me Frankie, you get out of here and take one fix, you're hooked again." "Don't worry about me buddy boy" "Let's get out of here." "Thanks Antic." "Take care of the dog for me. I've got a customer coming to get it." " Don't let him give you no gas." " Him?" "I ain't going to be around here long enough to let him bother me." " Don't let him give you no gas." " Him?" "I ain't going to be around here long enough to let him bother me." " l'm going to get me a job in a big-name band." " You're kidding?" "What do you think I stretching my wrist for buddy-o?" "The guy that teaches drumming down there, says I'm a natural." "I can't miss he says." "Arm's made of pure gold." "You mean a job winding these drums?" " l've got everything planned too." "Going to call myself Jack Duvall." " Probably I ain't going to see you around so much then, huh?" "Maybe I can set something up for you." "Carrying the instruments or something." " Travelling around the country high-type night clubs." " How does that sound to you?" "When is it going to be, when?" "Right away, today. I'm the kind of guy boy that when I move, watch my smoke." "But I'm going to need some good clothes." " Well you go on up. I'm going to find you some." " Yeah, yeah, size 39." " 39." " Stripes." "Something nice." "You stop that noise!" "You and your husband or I throw you both out." "Who is landlord?" "Me!" "You do as I say." "Your mother's eye socks, I do like you say!" "Frankie..." "You look great!" "How're ya feeling Frankie?" "I mean...." " Fine, fine, just fine." "Hi ya landlord." " She and husband fight all the time." "Hollerthrow things!" " Nothing changes." " This is respectable house, and I am respectable man!" "Respectable my eye!" "Go on get out, you're late for the parole board." "Frankie..." "You're home." "Oh Frankie, I love you so much!" "I've missed you so." "I've been so lonely Frankie, without you." " l've been so lonely without you." " Sssh, stop crying." "Let me look at you." " My eyes are going to be all red." " No, you look fine." " ls the cold sore gone?" " Yeah, you look real good." "I've had this cold sore, and I wanted to look real nice for you when you came back. I was afraid that it wouldn't be gone, so I put this cream on." "Everything is going to be all right.." "Oh, you didn't see." "Look, V got the cake by the bakery, but the sign I made." "Sort of like a welcome home." "Gee, it's like a real party or something." "Real nice." " How are you Frankie?" " l'm clean." "Sure?" " l kicked it for keeps." " Did it hurt?" "How was it there for you?" "They treated me fine down there." "There was this doctor, Dr. Lennex, he was real good to me." "Frankie!" "Did you miss me?" "Of course I missed you." "What kind of silly question is that?" "Of course I missed you." "Honest, no kidding." " What have you got there?" " You'll see." "Oh, I brought you something." " Oh, it an exquisite thing." " You like it?" "I made it myself, out of cigarette wrappers." "It's just an exquisite thing, that's all." "You made it?" "Yeah." "Yeah, for a hobby like." "You see part of the cure, was to keep yourself busy, doing things you enjoy" "Like for instance, I wanted to learn to drum and music." "And Dr. Lennex got them to help me do it." "During the day I was kept busy enough, butduring the night I'd get restless and I wanted to keep my mind of the craving." "I made that." " There's something important I've got to tell you." " What?" "I forget right now." "A whistle?" "I was scared sometimes being alone." "So Vi got it for me and I should blow for her when I wanted her" "Go on, you were telling me." "The first thing you do when you get there, is you talk to a doctor for about 2 hours.." "I know!" "I know what it is. I know what I wanted to tell you." "Vi took me to this movie and the girl's kid brother had a friend and who do you think he looked like?" " Who?" " You!" "That was a good movie." "Stage show was real good too." "We owe Vi 80 cents for the movie, I was broke." "We owe her for the cake too." "How come you didn't have any money?" "Swrick didn't kick in regualr?" " No." " Well, he was suppose to." "It was his joint they raided, not mine. I was just the dealer." "I kept my mouth shut and took the rap." " lf he didn't send 50 a month regular, how much did he?" " Well he sent 50, but not regular" "See Vi had to kick in for me sometimes." "She took good care of you?" "You had fun with her?" "Yeah.....but not like when you're here." "It was terrible being alone Frankie...and my legs when they hurt, she don't massage like you." " What do they say by the clinic?" " l stopped going by that goofy clinic." "The clinic must know what right." "You got to start the clinic again." "You got to get well." "Vi dreamed that this new doctor around the corner, he cured me. I'd have gone to him already, but he ain't free like the clinic." "But now you're back making money again, and I'll go." "I'm finished with Shrika. I won't deal for him no more." "But you always deal." "You're a dealer." "You're the best dealer in the business." "No more. I'm a drummer now.." " Don't make jokes Frankie. I never know when you're making jokes." " Who's joking?" "Listen." "Nice huh?" "It's Dr. Lennex. I told him my whole life story from when I was born, almost." "And about you and me." "But he told me that if I lived when I got out, like I lived before I went in there, chances are I would be hooked again in no time..." "So that's why I want to get with a band." "Listen." " How's that?" " Cute." " What did you tell him about me, this doctor?" " l told him about getting some money and getting you well." "Then he said getting with a band was a good way to go at it." "He even gave me the name of a guy right here in town, to get a job." "I mean with this man, if he's ever heard of this great doctor." "Most time these things just don't come through." " l got this." " What is it?" "It's a letter from the Doc." " l think I'll go call him now" " Now?" "Let's talk about it tomorrow." " You'll be all right." " You've haven't even tasted the cake yet." " l'll only be a minute." " l'll be right up." "No, now Frankie." " l'll only be a minute." " l'll be right up." "No, now Frankie." "First, taste a piece of nice....cake." " Hey, you coming baby?" " Yeah, I'm coming John." " Molly!" " Yeah, I'm coming John." "I want to talk to Mr. Harry Lane, please." " How about it huh?" " Machine, Mr. Franke Machine." "Yeah, I've got a letter of introduction for him." "From Dr Lennex." " Hello Frankie." " Dr. Martin Lennex." " How have you been Molly?" " Okay." "Come on baby, let's go." "A guy I met while you was away." " Mr. Lane. I've got a letter for you." " Come on, what do you say kiddo?" "This afternoon huh?" "Well I sure do appreciate it Mr. Lane, thank you very much." "Okay, good-bye." "Frankie!" "A new thing, by Brax Department Store." "No sales girls, you just help yourself." "It's what they call an honor system." "What's the matter Frankie?" "Feel that material." "And I figured, as long as I'm there...." "Nice huh?" "You all right?" "Frankie?" " l got the drummerjob." "Already?" "Wow!" "When I move, I move like a streak." "Think it looks all right?" "How come you ask me all of a sudden?" " l just want to know if it looks all right Sash?" "And my name ain't Sash, it's Sophia." "What's the matter?" "Nothing's the matter, 'cept how would you feel if your spine was hurting?" " Why didn't you say so?" " On account of it being your first day back, and I didn't want you to worry." " Don't be like that Sash." " ls it bad?" "Maybe the new doctor will do me some good huh?" " We'll go see him when I get back." " Oh, take me now Frankie." "Sash, I've got this appointment." "You know how much it means to me.." "We'll go as soon as I get back." " Please Frankie." " l'll hurry." " Well give me a little more massage first then, huh?" " Sash, I'm doing this for you to get some money so we can get you a good doctor." " Frankie..." " Look, I'll get you a dog too." "Get her a dog, will ya?" "I'll give the job my personal attention." "Just have confidence in the management." "Wish me luck Sash." "Frankie!" "Wait." "Wait Frankie!" " Wishes or wants, what could I do?" " Yeah, she just don't realize." " Shut up punk." "Just don't realize." "How would you like to be nailed to a chair?" "Frankie, Frankie, how are you?" "Well, it didn't do you no harm, did it Frankie?" " You look good." " That's right Shrika, it was a real country club." " They give you this when they let you out?" " They didn't give him nothing. I got it at Brax's." "I come as soon as I hear you are out. i figured you was worried about getting this job again." "Don't worry." "Shrika don't forget." " Job's waiting." " You need a dealer, you say?" "Do you?" "No!" "I've been dealing myself and I've built up a game like nobody's business. I've got a great following." "The play is bigger than ever." " l hear that you wasn't doing so good." " From who?" "When I say "great", I don't mean a lot, a few.." "loaded." " So, what do you want me for?" " Like I'm telling you. I take care of my friends." "Can I polish your halo Shrika, only a quareter" "Look, I've been doing all right." "But I don't say the customers like me better than they like you." "The dealer makes the house." " What do you say?" " No!" " You're dealing for some otherjoint?" " l ain't dealing for nobody I ain't dealing for nobody no more!" "is that the way you re-pay me?" "Didn't I send money to Sash?" "Here, I've gone and told all my friends that you'd be working for me again." "What am I suppose to do?" "As far as I'm concerned, you can go back to matching pennies with school kids." "Who is he?" " ls that a thing with them?" " They see each other." "You want to meet him?" " See ya Frankie." "Hey you..." " Get in dealer." " Who me?" "What for?" " You too punk." " l didn't do nothing." "Now wait, listen. I'm on my way to get a job. lt's important to me." " You can pick me up some other time." " l just need an hour" "Are you looking at being sued for liable or something." "I could sue you right now" " You're looking good Dealer, real good." " When did they let you out?" "Monday" " What's the charge?" " Shop lifting from Brax, this suit." " Who told you a thing like that?" " A little birdie." "A little bird with a cigar." " Shrika." "is that all you could stay out of trouble, two days, dealer?" "Listen, I got a chance at a job, playing with a band." "Honest, if you don't believe me, call the guy on the phone, he'll tell you.." " Just give me half hour, please." "Sure, you can have my badge too." " Book them and hold these two." " Look, all I need is a half hour Give me a break, will ya?" "I don't make the rules dealer." "You can't hold me. I'm incapable. I ain't smart enough to be running around loose, but I'm too goofy to be locked up." " Let go of the neck." " Let go of the neck. I've got a complaint." "Let go of the neck." "Hey you, I'm talking to you." "Oh the old silent treatment huh." "Let's have your number fella.." "Frankie, you got a cigarette?" "Do a cigarette trick, you knowjust to break the dirty monotomy." "Hello dealer. I come running as soon as I heard." "You want I should get you out dealer?" "The store will drop the charges, but 37 bucks is a lot of dough." "How do I know you'd pay me back?" " You fink!" " lt'd be different if you was dealing for me." " lf you want to deal for me, I can get you out." " You dirty lousy, stool pigeon." "I don't know what you mean." "Just trying to do you a favor." "Yes, or no?" "Okay..." "He took off like a whipped dog." "He's scared of you Frankie." " Nobody's ever been scared of me." "Them Krautz was scared of you." "You was a big man in the army." "Big man. I was the guy that picked the fly spots out of the pepper." "Get me out!" "Can you get me a fix?" " Big Ace's and here we go down and dirty" " Better luck next time." "I'll see that." "Coffee!" "Doesn't mean a thing, unless you have the King." "Bet more, win more." "ou still take tips dealer?" "Or don't they pay in the music game?" "What happened to that big job you had lined up?" "You stink out the joint?" "Give us a fresh deck.." "I decide when we need a fresh deck at this table.." " Hey Louie." "Borrow me a dirty dollar." " Get back at the door, lame-brain." " l take orders only from Frankie." "Don't give me lip you cheap little hustler" "Hustler?" "I'm ligit compared to some." "Ain't no 14 year old junkies waiting around to see me." "Do you want to die?" "nd here we go, down and dirty" "I'll deal the next one down.." " Sorry." " What's the sign of when a dealer's hands begin to shake?" "Take over for a while, will ya?" "All right men, new deal." "Okay men, here we go, down and dirty" "Ace.....seven....." "You know what's eating at you?" "You showed up the mob, for kicking it for keeps." "So now you're ashamed to think, well even what you think.." "Ain't that right?" "You know I don't talk about my customers, so who'd be the wiser?" "Why fight it dealer?" "Who, for what?" "Come over to my place." "What do you say?" "I'll be around." "They told me you was working here, so I was passing by and thought I'd come in and have a drink.." " Well, I've been here awhile." " Doing any good?" "All right." "Small cut of the game, usual cut of the drinks." " Ain't got all night." " Right." "Have something." " Fine." " Two doubles." " You didn't have to do that Frankie." " No reason you should be losing money by wasting your time talking to me." "You know you're no waste." "I was hoping you'd come see me.Y" " You know how it is Molly." " Sure, so busy now." "Here's to it Mollyo." "Mollyo. I haven't heard that since you went away." " You're looking good Frankie." " Feel good." " They tell me you're going to be a drummer now" " Yeah!" " l've got an appointment with a man tomorrow." " Oh, that's swell." " Probably I won't get the job though." " Sure you will." " l don't play good enough." " l bet you play fine." "You were always whistling and drumming on tables and things." "Real good too." "I mean it!" "You've got a natural rythm." "I was thinking, maybe of taking a stage name." "Jack Duvall." " Jack Duvall,Yeah, that's real class." " lt is, ain't it?" " That's a swell name. lt fits you Frankie." " This guy I'm going to see tomorrow, he books all the big bands." " lf l get on with him and wear a tux." " You look swell in a tux." " l already got the drums." " Pardon. I need a buck." "Ante up kid." "I got lonely.." "I needed somebody and he's a poor beat guy who needs somebody too." "Everybody needs somebody." " But you can do better than him." " Can I Frankie?" "Molly I...." "l thought a lot about you when I was away About you and me and Sash." "It would never work out between you and me as long as she is sitting upstairs in that chair lt'd be different if she didn't love me, and she wasn't so helpless." "You can't make a fool of someone if they love you and they're so helpless." "That's why I didn't come around sooner." "And that's why I ain't coming around no more." "You understand?" "Sure......sure I understand.." " You're a good girl Molly." " ...real good." "Frankie..." "Good luck with that fellow tomorrow" "You're not the first to come to me with a letter from Dr Lennex." " l've taken care of a lot of you people." "The doctor told me." "I like doing it, you understand." "So don't feel that this is charity, or anything like that." " Have you played professionally before?" " Only down at Lexinton." "I see, then you wouldn't mind auditioning?" "I mean I know some band leaders who might have an opening, but they'd have to be sure that you can play" " Oh sure, sure." " Okay..." "There's only one thing Frankie." "You see......" "A good many people like yourself, they mean well, but they're weak." "They let me down." "I mean I go to all this trouble." "Vouch for them, and they go back on the habit." " lt makes me look bad." " Oh, I wouldn't honest!" "I'm telling you this because, once a man lets me down, I'm done with him." "Even if he comes back on his knees." "And don't think that some of them haven't." " l wouldn't let you down Mr. Lane." " Good!" "I'll call you a week from Friday, about noon.Okay?" " l sure do appreciate it." " Oh, forget it." " Good-bye." " Good-bye." "Do you like my hair better this way, or swept up Frankie?" "Well you could at least tell me. lt ain't my fault he don't phone." "What did I say?" "Just don't hold your breath to hear from that guy, that's what I said." "He told you noon." "Here it is almost 6 o'clock already so how do you think he'll phone?" "I just don't want you should eat your heart out, is all." "Forget the whole thing Frankie, I bet he has." "I just don't want you should eat your heart out, is all." "Forget the whole thing Frankie, I bet he has." "You think he's got nothing better to do than to worry about you?" "Ha!" "Excuse me...." "Hello." "Oh, just a minute." "It's for you." "Hello.." "Are you Dr. Dominaski?" " Yes, I came as soon as I could." "Well, how you feel little lady?" " See, the doctor asks how I'm feelilng." " We'll have you feeling fine in one, two, three." "What is this?" "This happens to be an electric blood reverser and spine manipulator." " What's the gimmack?" " Gimmack?" "It so happens brother, that I am a member of the American Association of Medical Psycology, Hydrology and Divine Healing." "Where's the socket?" "cold hands." "Poor cirrculation." "Eat lots of hot things." "Chilies, peppers, hot sauces." " Pickles?" " Not more than 3 a day." "Now lean forward, and we'll vibrate the vertabres." " Know how I got like I am?" "My spine was hurt." "Oh I can see that." "Your ligaments and vertabres are locked together." "In a car accident it was hurt." "Three years ago, May 11th." "Maybe you read about it in the papers huh?" "This is the car that it happened in." "That's me, laying there." "My husband was the one driving the car and he was drunk." " Drunk?" " He got me in this accident and smashed me up good, so that I can't walk anymore or dance anymore." "And he married me right here, in the hospital chapel." " Sash!" " eeling a little better?" " Yeah, much better." "Hey Frankie, guess what?" "I got that dog for Sash." "Free spirit!" "Every claw and hair on him is a champion." "Champion of what?" "He brings back empties." "Here, I'll show you." "He's all dog." "You can make money out of him Frankie." "What he's really good at, is catching those squirrels in the park, and shaking the peanuts out of them." "Only thing he is trained to chase is a certain kind of squirrels and they're getting kind of rare in Chicago, because of the climate changing." "You know what I mean?" "So he's just hanging around, waiting for the climate to change back a little." "He's got a real fighting heart." "He's dizzy, but he still in there trying." " Take the dog up to Sash." " Frankie!" "You're not going with him!" "No!" "In a minute dealer." " Five bucks. ." " Last time, it was two." "It was more than 6 months ago, before you went away.." "They keep raising the price on me." "If they keep doing that, I'll have to find something to take its place." "The monkey's never dead dealer." "The monkey never dies." "When you kick him off, he just hides in a corner, waiting his turn." "The monkey will die waiting." "He ain't climbing up on my back no more." "Never again. I mean it." "Sure....." "Look Frankie!" "Look how he drinks it. lt's so cute." "He's got a thirst like a bar-fly." "Hello....." "You still expecting that connection to call?" "For you own piece of mind, forget him." "The Doc said that I could count on Mr Lane, and the Doc doesn't lie." "The Doc." "Look at me, a doc told you I'd be up and around in no time, and am I?" "Have you seen my sticks?" "Have you seen my drumsticks anywhere?" "You know what I'm going to get for this little dog?" "A little rain coat, like for when it rains." "Plaid maybe, or maybe all yellow" "Where are my drumsticks, Sash?" " How'd they get up here?" " You liked that, didn't you?" " Sash, I never keep them up here." " You drank it all up didn't you?" "Sash!" "I putthem there." "I stood right up and I putthem there, all right?" " No kidding?" " Maybe Vi, when she was straightening up for me. I don't know." "Stop picking on me." "Frankie..." "You can't keep stoning yourself about it.." "There must be a million drummers that play better than you, who can't getjobs." "Just remember that and you're going to feel better" "Yeah sure, I will." "Can the noise." " What's this for Sash?" " What?" "Oh Vi." "She laid it out for groceries." "We owe her even more." " You got any?" " No." "I don't know what we're doing with all our money" "Don't you get enough cards by Shrika?" " l just do it to kill passtime, that's all." " Well, what about my passtime?" " What did you say this was for?" " l sit here all the time and you don't even talk to me." "We got any more beer?" "I'd like some." "Beer bloats Sash, when you can't exercise." "Here pick a card." "Nothing is good for me. I am only 25 and it's like I'm an old lady already." " ls it my fault I can't exercise?" " Do you want to pick a card, or don't you want to pick a card?" "No, I don'twantto pick a card." "all I want isjust, isjust a Iittle...." "A little what Sash?" " Oh, just a little....." "A little beer, a little fun, a little anything." "I can't dance anymore, I can't swim and I can't even drink beer." "I don't even know what kinds they got anymore." "What other kinds they got these days Frankie?" "All right!" "Pretend I ain't here." "You're wishing all the time that I'd have gotten killed that night." "I don't wish any such thing." "If I don't talk, you get mad. lf l say anything, you bite my head off.." "I don't know whether I'm coming or going Sash." "I told you, it gives me headaches." "Well, I've got to practice sometime Sash. lf the job comes along, I want to be ready." "The job, the job!" "Take it to your girlfriend if you're going to practice." "What?" "Take them down and give her the headache." "Do you know what you're saying Sash?" "Do you know wht you are talking about?" " Don't give me that innocent look." " l haven't said two words to her since I come back." " Just cause I sit here, you don't think I know what goes on?" " Not two words." "I know plenty." "Cut it out will ya Sash." "Take them down to that tramp if you want to make noise." "Take them down to her, why don't you?" "All right, I will." "Frankie....." "Frankie, I didn't mean....." " l have 12 cents to a beer. lf l had 15, I'd be all right." " l've got 6 cents, here ya go." "I ain't going to stand it much longer The heartaches my old man gives me." "You know what he likes to do most?" "Tear the dates off the calendar, watching him." "That's suppose to be my big Saturday night pleasure." "Sometimes he loses all control and tears off the whole week at once." "He'll eat them like a billygoat." " Know what would fill up that empty spot in your life?" " What?" "A dog." "Ask a satisfied customer." "Frankie that dog I got you, it makes a big difference in your life, doesn't it." "Yeah." "I want to see." " l want to see you." "After the inning." "Hi Frankie." " You make out all right with the fellow with the job?" " The drumming job?" "Yeah, fine, fine." "Well not so fine." "He sort of tapped out on me." "He promised to call me, but.." "It's too bad." "There's a million drummers in the world and how do I rate?" "Maybe he lost your number?" "It happens." "Maybe he just wishing you'd keep in touch." "He'd think I was a pest." "Why should he?" "A good drummer, that's something that don't turn up everyday" "Come on Frankie, call him." "Call him Frankie." "Come on Molly, watch the game huh?" "Oh I don't feel like it Johnnie." "Why don't you go ahead, I'll wait for you." "Yes studio B, Monday morning, thank you Mr Lane." "Monday!" "I got an audition Monday Me!" "He told me to join the union and get ready to work." " Oh that's wonderful." " You know, he did lose my phone number" "He was trying to find me all week long." "Here I was ready to forget the whole thing." "Gee, if you hadn't opened your mouth, I wouldn't have called him." " Sure you would have." " l've got an audition with a big band." " Me on TV." " Practice a lot Frankie." "Practice?" "I'll beat those heads to a shred." "Only I got to find a place where." "Sash can't stand the noise." "Molly?" "Do you think I could put the drums in your place and sort of drop in once in a while?" "Why not?" "Molly, why not?" " ohnny wouldn't understand." " So, what could he do?" "It ain't a question of what he could do Frankie." "A fellow like Johnnie can't do much of anything." "It's a question of what it does to him. I'm all he has in the world, and I don't want to hurt him." " Molly, for crying out loud...." " l want you to know Frankie, a fellow like him......." " ..." "Sometimes when we're all alone...." " What does he do?" "Cry?" "He's a lush Molly." "He's a 100%/% habitual drunk!" "Look, everybody's a habitual something." "With him it's liquor, that's all." " Please Molly." "Mollyo." " lt ain'tjust that Frankie...." "l don't want it to start with us again." "Look what you said about us not seeing each other, it was the truth." "Even if we went away, I'd try to..... ltjust doesn't add up. lt never did, it never can." " Well give it a chance. I told you it would one day" "All my life's been "one day"." " On and on and on." " l've got drums, I'm headed for a good job. ls that so on and on and on?" "I make some money, I make Sash well." "What's so on and on about that?" " Don't shut me out Molly I'm trying." " You wanted to see me?" " No!" " What do you mean "no"?" " Vi!" "Here, for what we owe." "Frankie, Vi says can't trust me." "Tell her Frankie, what an honest hustler I am." "Frankie!" "I guess maybe you could drop in once in a while." "Thanks Mollyo." "See you tonight Molly." " How's that?" "Real nice." " You should have heard what I did a little while ago. .." " Good huh?" "I hope the neighbors liked it too." "I'm very big with the neighbors." "They keep banging on the pipes to let me know how much they appreciate it." " l won't let it go to my head though." " You keep playing drums at 5 a.m..... and you'll see what goes to your head." "Slip me a smile and I'll give you my autograph." "You won't have to fight your way through the bobby soxers to get to me." "I bet those bobby-soxers go for that." "Tired?" "Yes, but in a very nice way. I've been feeling good all night." " l joined the muscian's union today." " Shrika loan you the money?" " Him?" "Who did?" " Nobody. I'm going to hock the drums." " Oh Frankie!" " l've got it figured out pretty good." "When I get a job, I'll take an advance and get the drums out again. ln the meantime, I'll use the practice pads." "You should have asked Shrika." " Haven't even seen him." " You didn't go to work?" " No, I've been practicing here all night." " l quit the game Molly. ." " lt woulnd't have hurt you to wait a couple of days Frank." "I wanted to quit. I'm quitting a couple of things." "is it bad?" "Not too bad." " You shouldn't have started again." " Who knows why I started in the first place?" "I guess in the beginning you do it only for kicks. I got my first shot for nothing." "I thought I could take it or leave it alone." "So I took it." "And I took it again and again." "One day Louie wasn't around. I nearly went crazy till I found him." "Lord I was sick!" "." "I was so sick." "You can't be that sick and live." "That's when I knew I was hooked." "There was a 40 pound monkey on my back." "The only way to get along with a load like that, is to keep getting a fix." "Don't..... I'm one of the lucky ones, Molly." "I kicked it and I'm not too far hooked to kick it again." "I've had my last fix." "Tell me something." "Do you think those bobby-soxers' will really go for me?" "Yes, they will." "Maybe I'll get Sparrow a job with the orchestra." "And when I can get enough money together, I can get Sash into a real good hospital, so she can walk and dance again." "And then maybe..." " Who is it?" " Shrika, open up!" "Just a minute." " All right where is he?" " Frankie?" " Frankie!" "Where is he?" " Well what is it, what did he do?" "What'd he do?" "You know what he did, he quit!" "No notice, no nothing." "He sends words by that mistress that he's through. I had to take the spot myself." "Where is he?" " He wasn't at the game?" " Would we be looking for him all over, if he'd been at the game?" "He eats my bread." "Six years, he eats my bread." "He gets put away, I send you money regular." "He gets out and I give him his job back." " Shut up!" "What do you mean "shut up"?" "Do you think it was easy talking men like Williams and Marquee up to a two-bit game like you?" " Louis......." "Louis....." " l sold them on Frankie." "Why are we getting excited?" "They were a bat in the pocket and hungry for action." "We finally get a chance to score big.... ..and you lose the deal." "Look Louie I swear." "When Marquee and Williams come, the dealer will be there." "Or a playerjust as good. ..." "There ain't none as good." " Why didn't you offer him more money, a piece of the play." " From your end or mine?" "What's the difference, whose end?" "You expect me to stand here and argue about pennies?" "Look." "I'm a musician.." "Well, how does it feel?" "Well, it feels like...." "You'd better hang on to my arm, or I'll go up like a balloon." "I'm a musician." " Where are we going?" " l don't know, but I want to buy you something." " No." " l've got to spend some money or I'll bust." " How about one of those, only in green?" " Frankie..." " Maybe a color TV set." "They're pretty." "Would you look at this production. .." "And only for cooking." "Now who would want a thing like that?" " Boy, it's goofy huh?" " lt's pretty huh?" " l wonder what he does for a living?" " Him?" "He must make a nice dollar." "Look at the way he dresses her and a kitchen like that." "I notice he doesn't help her. I bet he didn't even marry the girl." "Look she ain't even wearing a ring on her finger." "She takes it off when she cooks, maybe and he's tired after a hard days' work." "Okay, let him sit there, but at least he could talk to her once in a while." "He doesn't have to sit there with his nose buried in a magazine." " l would talk to her." " What would you say?" "I'd say, how you been?" "How did it go today?" "What's for supper?" "Steaks for supper and everything went fine today" "Steaks!" "Good." "Now how about you and me stepping out tonight after we eat." " Why don't we just stay home and listen to music?" " Yeah." "I like that better." "We'll just stay home and turn on some music." "I wish it were Monday already." " Hi Sash!" " Where have you been?" " Shrika has been here." "He said you quit." "Where have you been?" "Look!" " Why did you quit him?" "I've got a try-out on Monday -lf the band leader likes me, I'm hired.Jeg har måske fået etjob med et band." "Frankie, go tell Shrika you was fooling, you'll deal." "Maybe this band leader won't like how you play" "Sash look. I joined a muscian's union." "Why do you got to go around changing things?" "Why can't it be like always?" "Why do you got to quit dealing Frankie?" " How we going to live with no money coming in?" " lt'll start coming in Monday." "Suppose they call this great "try-out" of." "You can't tell me it's a sure thing, can you?" "Frankie, deal for Shrika like always." "Forget this "great" job!" "I quit dealing Sash. I can't take the chance, don't you understand?" "If the joint gets raided and I get picked up again, Mr. Lane would be through with me." "And then how will I play with a band?" " How you going to play if Shrika gets your arms broke?" " What?" "Yeah, right here he said it." "And he wanted to slap me around too." "Why can't it be like always?" "A single." " You miserable piece of humanity." " l've got a right to quit if I want." " Marquee and Williams are coming tomorrow." " Don't you realize the signifigcance?" "Leave me alone." "I'll leave you alone. ln the alley with the cats looking." "That's enough Shrika. lf he don't want to deal, he don't want to deal." " What are you talking about?" " Don't you raise your voice to me, you slob." "He's no slave." "You can't force him, so what's the use?" " He...." " We've had the best of him all these years." "Don't be a pig!" "He ain't interested." "All right, all right." "Marquee and Williams have never heard of him." "Money?" "Something to blow your nose on." "I wash my hands." "He's just a pig, that's all." "Still you can't blame him, so much." "Let the biggest ones get away, because the best dealer isn't working for you anymore." "That ain't easy to swallow." "You're the best all right." " You're a squeeze player Louis." "Been tried on you before?" "NNah, I'm new around here.." " Are we really asking so much dealer?" " One night. I will..." "You help us make a bundle and we'll spread that sunshine around." "Couldn't you use a couple of hundred?" "Maybe 2 5 0?" "2 5 0 pays a lot of doctor bills." " Tomorrow huh?" " Frankie..." "Let him make up his own mind." "Okay, but for one night." "Win or lose." "Sunup, I case the deck." "Sure, you're the dealer." "What a load off." "Now I can sleep." "Take care of that arm." "Quite a character huh?" "Are you jacking up the price right now, or do you really have that music job?" "If they like what they hear." "Chancy huh?" "Nervous?" "So, what are we waiting for?" " Don't talk about it. lt's tough enough." "I know, I know. I put down a craving once." "No, candy, sweets. I used to be eating it all the time." "Got examined for the army and they said you've got sugar in your blood friend." "You've got to give up sweets forever, or it's good-bye Charlie." " l had to give up candy." " My gums bleed for you. lt's awful." "It was." "That unfinished feeling that you got all the time." "Well, I don't have to tell you." " So don't!" "l mean you got this one thing on the mind all the time." " Can't stop thinking about it." "You're just a mine of information aren't you?" "." "You know what I did?" "I said to myself." "Okay, off sweets forever." "Well, forever can start tomorrow." "For once in my life, I'm going to eat all the candy that I can hold. I bought 18 dollars and 20 cents worth of candy and lugged it up to my room." "All night long, I ate candy I was sick. I was sweating, but I kept shoving it in." "Ever since then, when I think about candy I say to myself, well you can't complain." "You once had it and had it good." "You know what I mean?" "How's it Mollyo?" " All right Frankie, but where have you been?" " What'll you have?" "A couple of ryes." "All day, I was expecting you'd be in to practice." "Practice?" "I'll get down there and knock them dead." "It's all in the wrist and I've got the touch Molly." "Look at that, steady as a rock. lt can do anything I want it to do." " Keep the change pal." " Thanks." " You got a cigarette Frankie?" " Sure." "You're on it again Frankie." "Why, why?" "No, listen Molly, listen." " Why?" "Molly!" " Molly..." " Beat it!" " Take a walk!" " Molly listen to me, I can explain." "Molly I just want to talk." "Will you get out of here!" " Molly." " Stop it please!" "." " You'll lose yourjob." "Can't you manage this." " Molly, listen to me." "Leave me alone, both of you!" "Molly!" "Molly..." "Molly!" "Molly..." "listen to me." "Molly. open the door." "Molly would you open the door" "Molly!" "Molly!" "molly...åben døren..." "Molly!" "Where are you going Molly?" " lf you let me explain, you'll know why I did it." " Taxi!" "molly will you listen." "Let me tell you what's happened." "Where you going Molly?" "No Molly!" "Molly!" " Don't forget to get it cleaned out." " l already cleaned it." "And say please when you talk to me, or I'll buy my own and go into business for myself." "How's that Frankie?" "Nothing huh?" "I'm reminding you Shrika, I get 2-21/2, maybe more." "Would I go back on my word?" "How're you feeling dealer?" " Hi ya Shrika." " Good-evening." " Yeah?" " ls this the place?" "I don't know what place you mean buddy This is the leather belt and company You want to buy a belt?" "Come right in." "We've just started." "How have you been?" "l could handle the door better if I was blind." " Oh, you couldn't heat towels for a barber" " Good-evening Shrika." " Good to have ya!" "You the machine?" "Man with the golden arm huh?" "Let's see you try and take this away.." "Here we go, down and dirty." "No ladies allowed, you know that V." " ls Frankie in there?" " What's the matter?" "Sash. I can't get her to sleep." "Her and Frankie had an arguement and she's almost out of her mind. ls he in there?" " Well, I can't call him now - l just want to know if he's here?" "l've been bounced around on the street like a pool ball." " l've been bounced around on the street like a pool ball." " l got to get back in." " Well tell him she's worried, if you get a chance." " Three aces." "Two pairs." "Possible straight flush." "Aces, two hundred." "I'll call your two hundred and raise you two." "I'll have a look for four hundred and I'll spot you three hundred more." "It's up to you." "l don't know, I just don't know." " You've got three aces, show him." " He's got a possible straight flush, with a queen showing." " l tell you he's bluffing." "He bluffed me out of a couple tonight." "You wouldn't be jerk enough to try it again, would you?" " Bet and find out." " Well bet, bet. I tell you he's a bluff artist." " Call it." " l call it and raise it 500 more." " Sammy!" " Jeg ved hvad jeg laver ." "I'll have a look and house bumps you 500 more." " l told you, I told you he had it." " Shut up and let me think." " lt's up to you." " What's the rush, I want to know?" " Your bet, two pairs." " l heard you." "What is this?" "A forced game?" "A man has a right to study his hand." "Bet or fold!" " Lose your hand Sammy." " l tell you he's got it, don't throw good money after bad. I know what I'm doing." "What'd you have?" "You didn't pay to find out." "Nothing." "A lousy two nines." "You let him bluff you out of a full house, with a lousy two nines." "You do that again at this table, and you're through." "Ah, forget it this once dealer." "He paid plenty for it." " You're good dealer, maybe too good." " What do you mean by that?" " Cut the talk." "Deal, deal." " Come on, get some of this smoke out of here." " What do you mean too good?" " lf the shoe fits brother." " Okay, that's it for the deck." " What?" " What?" " Well, we always break up around now" " One more round." "What about my money?" "One more round." "What about my money?" " Frankie, how about it?" " Nope, just give me what's coming to me." " One more round huh?" "I'll deal." "You?" "We want to play Machine." "You think I can't sell you a thing or two?" "Sit down and we'll get going." " What about my money?" " As soon as we break." " Give us a chance." "Go home." " home." "You'll get it later." "Okay, ante up, here we go." " 100." " Yeah....100..." "Okay, here we go." "Good morning Frankie." " ls Louis still here?" " He's doing an apple plexy but they're doing a sweet in there." "We're getting murdered." " You got to get in here and start dealilng. I ain't taking the slot." " Look." "You got to make it stop." " No deal, no fix." " Give me my money and I'll go see someone else." "Give me my money and I'll go see someone else." " You owe it to me." " Take me to court." " You got to make it stop." " You got to make it stop." "I've got to get some sleep. I've got to be fresh tomorrow." "Work a few hours, do us a favor. I'll guarentee you'll feel like a week." " Please Louis, now." " Drop dead!" "Wait a second." "Okay..." "Louis says you've got money for him." "So give it to me, he's waiting." "I know he's waiting." "They all say the same thing." "Tell Louis, like he tells us, nothing." " Not a penny?" " Nope." " How is it up there?" " How is it up there?" " The dealer is losing huh?" " What happened to that golden arm?" "Don't worry about the dealer." "The game's just going on a day and a half, he'll come through." "Why not, with those educated fingers." "Now you see it, now you don't." "You keep your dirty mouth off the dealer." "Frankie runs a clean game and there ain't nothing in the world that could make him change that." "Hey Antak...." "All right, all right." "Can you let me have 1000?" "Hold it a minute." "Give me some of that." "I've got to get out of here Louis. I'm dead. I haven't slept in two days." "It'll be just a little while now I ain't doing you any good." "The house is still losing." "Stay with it dealer, the class is beginning to tell." "Just stay with it.." " l just can't." "My head won't work no more." " Louis der er ikke flere at ringe til." " Lippy." " Can't find him." " l'll find him." "He's loaded." " l'm getting out of here." "Just a little longer I'm going to make a call, then I'll take you over to my place." " Now where were we." " Jeg vil se." " Coffee?" " Good and black!" "l can't raise another cent" " De bliver ved at smide penge på bordet" "Every pot almost, they're raising and raising until we are forced out." " What day is it?" " Kan du ikke finde nogen vi kan låne af?" "What day is it?" "is it Monday yet?" "Listen to me..." "Are you listening to me?" " Hvad?" "The next big pot they try are forcing you out, you've got to stay with them." " Shrika won't let me." "He keeps nudging me to fold." "Shrika won't let me." "He keeps nudging me to fold." "You can't be sure though." "There's a way you can be sure." "You can do anything you want with those cards." "That's only for fun. I haven't got nerve to do it for real." " You want to get out of here, don't you?" " What?" " You want to get to that try-out in good condition, don't you?" " Yeah, I want to get there feeling good." "Well then make sure, you know what I mean." "Let's get on with the game, I feel hot." "Okay dealer..." " l'm in." " l'm in." "Three." "King." "Jack. ." " l think that's enough." "Call." " Pair of strays." "I'm back with 500." "House sees." "Three strays, King, Jacks." "I bet 500 bucks." " Take off your glasses." " No!" " l didn't know. I didn't know." " l'll get to you in a second." "I didn't know. lt hasn't happened before." "Ask anybody." "You don't deal for me no more." " You want him?" " l wouldn't dirty my hands." "How was I to know." "You fellows, you know I've been running an honest game." "Tell them!" "Frankie..." "Everything's all right now Frankie." "Frankie, what's a little cupping around huh?" "Nothing." "Am I right?" "You'll see." "You should have seen Shrika's face, when Williams said he'd get to him in a minute." "He went white!" "It was so funny" "Cut it out, you hear me!" " You was the best sport I knew my whole life." " You hear me?" "Stay away from me punk!" " Hurry quick!" " l want to get some sleep." "It's beginning to wear off quit for you?" "You're a graduating student." "You're going to have to step it up." " Please hurry." " All right" " Let's see your money." " Later, later!" " Right now." " Trust me this once, will you?" "No, I don't do that." "I'll pay you twice as much later, but I got to do something right now." "I'll even push for you." "Louis heard." "A flipping junkie always says that." " Louis, please." "Get your dirty hands off me." "Frankie..." " Wake up." "Get up!" " Where did you put it?" " Where do you keep it?" " Let him go." "I can't find it." "Frankie, please let me take you home." "I've got to be on time." "Frankie..." "What's the matter." "Come on, let's try to really cook it." " Mr. Machine." " Mr. Lanes." " Can you read music?" " Yes." "Shelby, let Mr. Machine sit in on this one." "Number 37, it's right in front of you." "Do you know it Mr. Machine?" "Okay, let's try." "Mr. Machine, the first four bars are all you." "Come on, let's try it again." "One, two, three, four." " l'm sorry. ." "Are you all set?" "Once again." "One, two, three, four" "Okay Shelby, let's go." " Sash, have we any money?" " l need some money." "No, what's the matter?" "There was some around here yesterday, wasn't there?" "I need some money Sash." "There was some around here yesterday, wasn't there?" "I need some money Sash." "Well, there isn't any." "What is it Frankie?" "What is it?" "You can walk?" "Since when?" "What's the angle?" "What are you and Frankie trying to prove?" "Come on tell me." "One hustler to another" "Let me in on it or I'll croon for it, you hear?" "I'll tell everybody you can walk, you always could." "I'll tell them all you can walk, you old phoney!" "." "No...." "Louis!" "." "No Louis, you can't do that." "You can't tell anybody Please Louis." " Keep your hands off me." " Please Louis." "Molly..." "Molly." "Ain't that the way it happened?" "They had a fight and the next thing you know, Louis is falling." "Come on, level Sash." "Don't try to out-think me, you'll only get tangled." "I don't know anything about a fight. I was sleeping the whole morning, right here in this chair" "Then for all you know, it did happen that way While you were sleeping, Frankie shoved him over." " He didn't!" " How do you know it?" "You were sleeping." "It wasn't like I was sleeping, more like dozing kind of." "I'd have heard a fight, if there was one." "Frankie didn't do it, he wasn't even here." " When wasn't he here?" " When it happened." "How can you be sure if you was dozing?" "I was up when he left." "That's how I'm sure." "I saw him go." "And he was home this morning." "Only a second." "He didn't get in a fight, he was here only a second." "Why didn't he stick around?" "Was somebody after him?" "Nobody was after him, nobody." "He just wanted some money is all." " Money?" "What for?" " l don't know what for." "Afix!" "He wanted it for a fix from Louis." " lt had nothing to do with Louis." " How do you know?" "Cause there was no money." "Why would he want to see Louis for a fix, he there was no money?" "To try and get one without money" "Okay, I can wait." "Wherever he is, sooner or later he's got to come up for a fix." "Molly, Molly wait please." "It's finished Frankie." "Like I told you." "But I've got to talk to you Molly," " No!" "Once and for all!" "Molly, I've got to talk to you." "You got any money Molly?" "I need a few dollars." "10 dollars would do it. I'd get it back to you in a few days." "Or 5 even." "Five would be fine, please." "I feel so sick Molly. I hurt all over. I feel so bad." "Don't say no, please don't say no." "Why not Molly why not?" "Jump off a rope if you're going to kill yourself, but don't ask me to help you." "I'll do anything for you Molly..." " But right now you've got to help me. I need a shot." " No!" "Five would do it, or three or two even, but please hurry." "You mustn't take that dirty stuf no more." "I know, I know you're right. I promise, but right now I just need a fix." "Just one fix." "It'll help me stop hurting." "Then I promise you, I'll kick it for good." "Just a few dollars Molly." "Hello Molly. I just wanted to come and say hello." " Ain't you going to let me in?" " l asked you please to not bother me any more." " l miss you." " Look, I'm awfully tired Johnny." " l'll stay only a few minutes." " No." " Who's in there with you?" " Go away Johnny and don't come back." "Who is it?" "Not the dealer!" "You ain't hiding him, are you?" " You wouldn't be dumb enough to be an accessory would you?" " What do you mean accessory?" "He killed Louis." "The cops are looking for him this minute." " Frankie Machine." " ls he in there?" " No." " l'm coming in!" "Not if you ever want to see me again." " Will you meet me tomorrow." " Yeah, I'll be around the bar" "Maybe not tomorrow, but soon." "I miss you." "Honest, I didn't." "What am I going to do?" " Go tell Bedner, it wasn't you." " l couldn't." "I couldn't stand up to the cops the way I am." "Look at me. I'd say anything they'd want me to say just for a shot." " Then get cured first." "What are you talking about?" "How am I suppose to get cured." "You did it once.." "That was with help, with medicine and doctors." "I can't go apply at Lexington with a murder hanging over my head." "Couldn't you do it without going there?" "You mean just stop?" "Cold turkey?" "You don't understand." "The pain." "What else can you do?" "All I need is just one shot, just one." "Okay." "All right, here take it!" "Here, go on take it all." "Cause after that one shot, all you're going to need is another." "And then another and another Take it!" "Take it!" " Why should you hurt, like other people hurt?" " You had a dog's life, but never a break." "hy try to face it, like most people do?" "No just roll up all your pains, into one big hurt and then flatten it with a fix." "What do you think you'll find just outside that door?" "Don't you think Bedner knows what you are, and what you need?" "Just to get through that next hour..." "Don't you know, he's just waiting for you to come and get it." "Go on." "Let him kill you!" "Let him kill you. lt'll be quicker and better than doing it your way." "No!" "No!" "I won't let him kill me." "No!" "And I won't run into no grave." "But kicking it......" "A guy can't do it by himself." "I'll help." "You know what you are letting yourself in for?" "It ain't pretty." "And it could be dangerous." "If they find you here, then they find you, is all." "I don't mean dangerous from Bedner. I mean dangerous for me." "Sometimes a junkie will kill, to get away from the treatment." "Understand?" "So if you've got any knives or scissors in the house, you've got to put them away for a while." "And don't let me out of the room." "No matter what I say, or promise, or how much I beg." "Cause if I get out, it'll only be for a fix." "That's the way it is." "Do you understand?" "Just lock me in the room." "And if I try to make a break for it, just stop me any way you know how" "And no matter how much you see it hurting me, don't try to help me with pills or dope or anything else." "Do you think you can handle it?" "Here we go." "Down and dirty." "You can't hold me." "Sit down." "You can't hold me. I ain't got all my marbles, you know that Captain." "Write down the cases Sparrow." " l didn't do nothing." " But Frankie did something all right." "Now, I want you to tell me about it." "Whoever killed that peddlar, should get a ticker-tape parade." "Yeah, and maybe I'd lead the band, but I still want you to tell me about it." "Listen to me Sparrow." "When we catch him, he stands trial, whether you talk, or whether you don't." "The only question is, do I ticket you as an accessory?" "Bedner, don't nail me to the cross." "He's the only guy I've ever had for a friend." "He's nobody's friend anymore." "He smash you with a steam roller, if you got between him and a pop in the arm." "Come on talk Sparrow." "Okay, beat it." "Let me out!" "Yes?" " l thought I'd come and see how you've been Sash." "All alone, that's how I've been." "Something to eat." "Sausage." "All alone and worried sick." "Where is he?" "Do you know where he is?" "Did he go to you?" "What do you want anyway?" "What do you want anyway?" "I didn't tell Bedner anything." "The papers, they twist everything all up." "They wouldn't be able to, if you didn't let them." "I can't help what they do." "What do you expect me to do, sitting here?" "Just tell Bedner that Frankie wasn't here when it happened." "That he didn't do it." " l never said he did." " But that's how it sounds, if he was the only one around at the time." "And you know it was somebody else." "What do you mean?" "Who?" "don't know." "But maybe Bedner could figure it out if he didn't think it was Frankie." "What business is it of yours anyway?" "I just want to help, that's all." "Who are you kidding?" "You think I don't know what you really want?" "You think I don't know what you and him have been up to behind my back, while I had to sit here all these years?" " Had to sit here all these years." " No Sasha, you've got it wrong." "No!" "You've got it wrong!" "He put me in this chair, and as long as I sit here, he'll never leave me." " He knows he belongs to me." " Sash, I came only to help." "I wouldn't want to live it he left me, and I would rather see him dead, than go to you." " Sash, please." " YES, get out of here!" "GET OUT OF HERE YOU LOUSYTRAMP!" "Get out!" "Frankie NO!" " l can't stand it any longer" "Just a little longer." "Please help me." "Keep me warm." "I've got to get out and get a fix." "Open the door, or I'll kill you.." " l'll kill you." " Frankie, listen, if you......" " But I do have something put away to make it stop." " Give it to me quick!" "Where?" "I'll get it." "Molly!" "Molly!" "Let me out!" "Molly open the door." "Frankie?" "Frankie, answer me." "Frankie answer me." "Are you all right?" "Don't think you can fool me into opening this door I won't." "Are you all right Frankie?" "Please answer me." "Molly, if you love me, kill me, please!" "Oh, I'm so cold." "Make me warm." "Molly..." "Please Molly, make me warm..." "Oh Molly, I'm so cold!" "Oh God, O God." "Please make me warm Molly." "I'm so cold.." " l waited for you in the bar." " l told you it might not be right away I thought maybe you were sick or something. I just wanted to tell you, don't look for me at the bar anymore." "He threw me out last night, we had a little argument." " So make it the Safari huh?" " Yeah, sure Johnny, sure." "Pretty good, huh Molly?" " Take it slow now." " Oh, I'm all right." "Just a little rocky." "It's the most gorgeous day I ever saw." "I think it's the first day I ever saw." "I've got a craving for something sweet." "Have you got anything sweet?" " Sugar?" " Gimme!" "More, come on, more." "How can you Frankie?" "I neverfeltthis good In my Iife." "I feel like all the things Insise of me are settlIIng Into place." "Thanks Molly." "Mollyo!" " Look out, you'll scrape your face off!" " l don't care." " You got a razor I can use?" " Can I trust you with one?" "Cross my heart." " ls this the place?" " Yeah." " Okay, come on." " No please, you don't need me up there." "Where is he Molly?" " He didn't do it, honest." "I'm not a judge." "They pay me to bring him in, that's all." "If you tell me where he is, I promise you that he'll get every break a jockey can get." " He's no jockey either." "That's finished." " Oh sure, you bet." " You can see for yourself." " He ain't running away from you." "So, where is he?" " With Sash." "All right Molly." "Let's go see." " Hello Sash." " What are you doing here?" " Frankie, don't you know that Bedner is looking for you?" " Don't worry about it Sash, I ain't afraid." " l didn't do it and you know that" " Who did then?" "I've come to tell you something Sash....." " l'm leaving here." " Bedner will arrest you." "He told the newspapers you....." " What?" " l'm leaving." "You won't have to worry about money or anything. I find a way to send some regular to you ." "And Vi will take good care of you." "Leaving me!" "?" "Not leaving you Sash, just leaving." "You saw what happened since I came back." "Like Dr. Lennex told me..... I got in the same old routine and before I knew it, I was on it again." "But you can't leave me." "You've got to stay and take care of me." "I know I'm responsible for how you are Sash.... but I can't go around the rest of my life stoning myself about it." "I've been carrying my heart ever since it happened." "Even now it hurts me to think about it, but....." "Well, it's not that I want to leave, I've got to leave." "You mustn't leave Frankie!" "You mustn't." "Sash...." " Say good-bye to me Sash." " You think you're fooling me?" "I know what's pulling you away Molly!" " No." " Yeah, you just go so that you can be with that little tramp!" " Frankie no..." " Good-bye Sash." "No Frankie, please don't leave." "Frankie no, don't leave me." "Get dressed Sash.." "Sash!" "Sash Stop!" "Sash!" "Sash!" "Sash, don't move." "Don't try to talk." "You're going to be all right." "I love you so much!"

Non-resective ablation and liver transplantation in patients with cirrhosis and hepatocellular carcinoma (HCC): safety and efficacy. We investigated the efficacy of nonresective ablation techniques and the tumor-free survival of cirrhotic patients undergoing liver transplantation for hepatocellular carcinoma (HCC). In group 1, 11 HCC patients were treated with these techniques and transplanted. On the waiting list, patients were treated to complete ablation, judged by gadolinium-enhanced MRI and alpha-fetoprotein (AFP) levels. Group 1 was compared with a concurrent group of 10 liver transplant patients (group 2) with incidental HCC (stages T1 three patients, T2 seven patients). The group 1 patients received 36 procedures (4 alcohol ablations, 14 trans -hepatic artery chemo-embolizations, 15 trans -hepatic chemo-infusions, and 3 radio frequency ablations) for treatment of 13 liver masses. Tumor-node-metastasis (TNM) stage was reduced in eight patients (72.7%), unchanged in two patients and increased in one patient before transplantation. The mean waiting time for transplantation was 12.9 7.6 months. Both groups had a tumor-free survival of 100%, at 30 12 months post transplant. On pathology, 54.5% of explanted livers had residual viable HCC after tumor treatment, and 36.4% (4/11) explants had synchronous lesions. Non-resective ablation therapy is safe and effective in reducing the HCC progression in cirrhotic patients awaiting liver transplantation. The cancer-free survival rate in this treatment group is equal to that for incidental T1-T2 HCCs.

This invention relates to a valve system for a pressurized fluid container, such as a bottle or tank containing hydrogen gas under pressure. It also relates to a container incorporating the valve system and a connection system for connecting one or more of the containers to a gas intake port, such as a gas intake manifold of a fuel cell system. Hydrogen is typically stored as a compressed gas in a suitable container which is pressurized and equipped with an external valve to turn the supply of gas from the container on and off. In order to facilitate connection of the container to, say, a gas intake manifold of a fuel cell system, so-called quick coupling mechanisms or quick connectors may be considered. One such quick connector comprises mutually engaging (bayonet type coupling) male and female members to provide a gas tight seal when engaged. Typically, the male member is provided on the container and the female member is provided on the manifold or more specifically, a support rail of the manifold. When in the engaged position, gas can flow from the container through the manifold and into the system for which it is required. The disadvantage of this arrangement is that, if a connector has a slow leak, the contents of the container will leak away, even if the system is not in operation. Apart from resulting in the wastage of fuel, the accumulation of a gas such as hydrogen in air produces a combustible mixture which can result in an explosion if exposed to a spark or other ignition means. According to the invention there is provided a quick connect fitting for a pressure fluid container, the fitting comprising a solenoid-activated valve for controlling outflow of fluid from a pressure fluid container, the valve having a valve body defining a chamber therein and means for connecting the valve body to a pressure fluid container with the chamber in communication with the interior of the pressure fluid container, and further comprising a valve opening in the chamber for permitting the outflow of fluid from the container through an external fluid outlet on the valve body which external fluid outlet is in communication with the valve opening, a solenoid and an armature for activation by the solenoid, a reciprocal valve stem provided with a valve seal for closing the valve opening to the flow of fluid therethrough, the stem being connected to the armature for movement of the stem to open the valve opening when electrical power is supplied to the solenoid, and wherein the solenoid has a first terminal which is connected to an electrical conductor located on the exterior of the valve body and electrically insulated from the valve body and a second terminal which is in electrical communication with the valve body for grounding the solenoid to a pressure container to which it is connected. The valve body may be provided with a coupling member for connecting the external fluid outlet on the valve body to a fluid intake port of a consumer system to which the fluid is to be supplied, the coupling member being for engagement with a mating coupling member on the intake port. The electrical conductor on the exterior of the valve body may be arranged for contact with an electrical conductor on the intake port upon engagement of the coupling member with the mating coupling member on the intake port. The fitting may further comprise a coupling mechanism for connecting the external fluid outlet on the valve body to the fluid intake port of a consumer system to which fluid is to be supplied, wherein the coupling mechanism comprises first and second mutually engaging coupling members, the first coupling member being located on the valve body and the second coupling member being located on the fluid intake port. The intake port may be one of a plurality of inlet ports on a manifold for receiving a plurality of the containers. According to another aspect of the invention there is provided a quick connect fitting for a pressure fluid container, the fitting comprising a solenoid-activated valve for controlling outflow of fluid from a pressure fluid container, the valve having a valve body defining a chamber therein and means for connecting the valve body to a pressure fluid container with the chamber in communication with the interior of the pressure fluid container, and further comprising a valve opening in the chamber for permitting the outflow of fluid from the container through an external fluid outlet on the valve body which external fluid outlet is in communication with the valve opening, a solenoid and an armature for activation by the solenoid, a reciprocal valve stem provided with a valve seal for closing the valve opening to the flow of fluid therethrough, the stem being connected to the armature for movement of the stem to open the valve opening when electrical power is supplied to the solenoid, and further comprising a coupling mechanism for connecting the external fluid outlet on the valve body to a fluid intake port of a consumer system to which fluid is to be supplied, wherein the coupling mechanism comprises first and second mutually engaging coupling members, the first coupling member being located on the valve body and the second coupling member being located on the fluid intake port and wherein the solenoid-activated valve is located upstream of the coupling mechanism. According to a further aspect of the invention there is provided a container for storing a fluid under pressure, including a solenoid-activated valve for controlling outflow of fluid from the container, the valve comprising a chamber which is in communication with the interior of the container, a valve opening in the chamber for permitting the outflow of fluid from the container through an external fluid outlet on the container which is in communication with the valve opening, a solenoid and an armature for activation by the solenoid, a reciprocal valve stem provided with a valve seal for closing the valve opening to the flow of fluid therethrough, the stem being connected to the armature for movement of the stem to open the valve opening when electrical power is supplied to the solenoid, wherein the solenoid has a first terminal which is connected to an electrical conductor located on the exterior of the container and electrically insulated therefrom, and a second terminal which is in electrical communication with the container. According to another aspect of the invention there is provided a container for storing a fluid under pressure, including a solenoid-activated valve for controlling outflow of fluid from the container, the valve comprising a chamber which is in communication with the interior of the container, a valve opening in the chamber for permitting the outflow of fluid from the container through an external fluid outlet on the container which is in communication with the valve opening, a solenoid and an armature for activation by the solenoid, a reciprocal valve stem provided with a valve seal for closing the valve opening to the flow of fluid therethrough, the stem being connected to the armature for movement of the stem to open the valve opening when electrical power is supplied to the solenoid, and further comprising a coupling mechanism for connecting the external fluid outlet on the container to a fluid intake port of a consumer system to which fluid is to be supplied, wherein the coupling mechanism comprises first and second mutually engaging coupling members, the first coupling member being located on the container and the second coupling member being located on the fluid intake port and wherein the solenoid activated valve is located upstream of the coupling mechanism. Further objects and advantages of the invention will become apparent from the description of preferred embodiments of the invention below.

Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the South-South region, Nigeria 2011-2014. To demonstrate the immunity status of children with non-polio acute flaccid paralysis (NP AFP) reported through the AFP surveillance system in the South-South region of Nigeria. A retrospective study was conducted using AFP surveillance data collected routinely between January 2011 and December 2014 by the Disease Surveillance Department of the regional health service and the World Health Organization (WHO)-accredited regional reference polio laboratory. All cases of AFP reported to the Disease Surveillance Network from all six zones during this period were included in the study. In total, 5111 cases of AFP in children aged ≤15 years were reported between 2011 and 2014. These cases were investigated and verified by WHO surveillance officers using a standard questionnaire, which captured the number of doses of oral polio vaccine (OPV) received by the child. Two stool samples were collected for each case, 24-48 h apart, within 14 days of the onset of paralysis, and transported to the national polio laboratory under reverse cold chain storage. Data retrieved were stored in an AFP database hosted by the WHO server. EPIINFO software was used to query the database and extract the information required for analysis in this study. The percentage of children who had received at least three doses of OPV (which serves as a threshold to measure immunity status) decreased from 87% in 2011 to 82% in 2014. The percentage of children who had not received any doses of OPV decreased from 2% in 2011 to 1% in 2014. Forty-eight percent of the children who had not received any doses of OPV were aged <1 year. Given the decrease in OPV immunity status, the region risks re-introduction of poliovirus. Swift steps should be taken to improve the immunization coverage, which would boost immunity status in Nigeria.

The present invention relates generally to semiconductor devices, and more particularly, to high frequency signal isolation in a semiconductor device. To reduce cost in integrated circuit design, it is desirable to include as much functionality as possible on a single integrated circuit. For example, in a low cost wireless communication system, it is desirable to include the RF (radio frequency) circuits on the same integrated circuit as the digital logic circuits. However, noise generated by the digital logic circuits can be injected into sensitive RF circuit blocks such as phase locked loops (PLL) and low noise amplifier circuits. Conceptually, an ideal Faraday cage prohibits external electromagnetic interference and provides perfect signal isolation. In an integrated circuit, implanted wells are used to reduce the effect of noise and to provide signal isolation. In a CMOS twin well process with a p-type substrate, the pn junction between n-well and p-type substrate provides some signal isolation for PMOS. The NMOS signal isolation is accomplished using a deep n+ implant (DNW) with an n-well to create an isolated p-well (IPW) pocket, and is sometimes referred to as a triple well process. Implanted wells as used to approximate a Faraday cage in integrated circuits, reduce the effect of noise. However, the use of implanted wells fails to provide adequate signal isolation at higher RF frequencies. FIG. 1 illustrates a top view of a prior art semiconductor device 10. FIG. 2 illustrates a cross-sectional view of the prior art semiconductor device 10 of FIG. 1. Semiconductor device 10 has a p substrate 18. A deep n-well implant 16 together with a n-well ring 15 creates an-isolated p-well pocket 12. A plurality of p+ well ties 14 is implanted in the surface of the isolated p-well 12. Electronic circuits are built into the surface of the isolated p-well (not shown). The isolated p-well 12 functions to isolate the circuits implemented in the well from circuits that are implemented outside of the well. However, the deep n-well implant 16 has a relatively high resistance that is undesirable for signal isolation in the RF frequency range.

1. Field of the Invention This invention relates to an automatic broadcast wave tuning device and, more particularly, to an automatic broadcast wave tuning device for a radio data system (hereinafter referred to as RDS) receiver to receive RDS data wherein the radio receiver is controlled to tune in a broadcast wave bearing RDS data transmitted by a broadcasting station. 2. Description of the Prior Art As a well known radio service, a radio data system (RDS) is common in Europe for providing broadcast wave listeners with a radio service. In such RDS, informative data relating to broadcast programs are transmitted simultaneously with the broadcast programs in a multiplex modulation from broadcasting stations and, upon receiving the broadcast waves, a desired broadcast program is selected by a broadcast wave listener based on demodulated data. The RDS is a data system standardized in the Europe Broadcasting Union (EBU), wherein the data relating to the broadcast such as broadcast programs and the like are coded into a two phase Differential Phase Shift Keying (DPSK) signal having a bit rate of 1187.5 bps, and these coded data are transmitted by frequency-modulating a sub-carrier in such that modulating a 57 KHz sub-carrier in accordance with a double-sideband carrier suppression amplitude modulation. In the RDS, the whole data are transmitted as a unit which is called a group consisting of 104 bits. One group in turn consists of four blocks, each of which consists of 26 bits. The data contained in each group are prescribed depending on their locations, whereby 16 bits of the first block always designate a program identification code (PI code), while in the second block, the first 5 bits designate a group-type code, the next one bit designates a traffic-program identification code (TP code), and the next succeeding 5 bits designate a program type code (PTY code). Further, the contents of the remaining are a traffic announcement identification code (TA code), program service name data (PS data) such as broadcasting station names, broadcasting network names and the like, and a list of alternative frequencies data (AF data) for identifying broadcasting network stations which broadcast the same program. In a motor vehicle-mounted RDS receiver, a poor reception is quite often encountered while listening to a broadcast during a motor vehicle travel. However, in the RDS broadcast, since the AF data of the broadcasting stations within the same broadcasting network, which stations are broadcasting the same broadcast program on different frequencies, are available as described above, it is possible to tune in another broadcasting station within the same broadcasting network having a greater signal level, or a stronger electric field strength, than that of the broadcasting station presently tuned in based on the AF data stored in a memory for chasing the same broadcast program. However, there has been a problem for causing faulty operation of the RDS receiver depending on a course of the motor vehicle such that the RDS receiver might come across a broadcasting station, out of but neighboring to the broadcasting network, having the AF data allocated to the same frequency as that of the broadcasting station within the broadcasting network, or the RDS receiver might tune in a wrong program as there are so-called non RDS broadcasting stations which are not capable of transmitting RDS data. This kind of faulty operation often happens when the motor vehicle is driven through many countries in Europe along the boundaries. Further, wrong AF data may have been stored in a memory due to an unknown reason in a duration of demodulating the received RDS data and this results in a problem for causing improper selection in the automatic tuning operation. A prior-art-type automatic tuning device is disclosed, for example, in the patent application laid-open No. 2-105731. It is therefore an object of this invention to eliminate the problems encountered by prior-art-type RDS receivers and to provide an automatic broadcast wave tuning device which is capable of preventing a RDS receiver from faulty operation.

It is well known in the art that shock loadings and forces applied to the underside of the foot of a person via the sole of footwear article have long term effects on the integrity of joints of a person, whilst also at times causing pain and discomfort, in particular when wearing footwear for extended periods of time. Furthermore, it is well known that the majority of loading on impact to the foot of a person is imparted to the underside of the heel portion of the foot of a person in use. Footwear articles of the prior art include various manners in which to increase comfort and conformity to the foot of user, including shock absorptive inserts, various types of foam rubber and air cushioning devices. Such footwear articles typically require increased manufacturing costs and tooling, thus increasing complexity of production. The present invention is provides a footwear article which overcomes or at least substantially ameliorates at least some of the deficiencies as exhibited by those of the prior art.

Long-term results of guided tissue regeneration therapy with non-resorbable and bioabsorbable barriers. IV. A case series of infrabony defects after 10 years. A 10-year follow-up study was conducted to clinically evaluate the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers. Twelve pairs of contralateral infrabony defects were treated in 12 subjects with advanced periodontitis. Within each subject, one defect received a non-resorbable barrier and the other received a bioabsorbable barrier by random assignment. Clinical parameters were obtained at baseline and at 12 and 120+/-6 months after surgery. Eight of 12 subjects were available for the examination at 120+/-6 months. Twelve and 120+/-6 months after GTR therapy statistically significant (P<0.05) vertical clinical attachment level (CAL-V) gain was observed in both groups (3.4+/-1.0 mm and 1.5+/-1.2 mm for the control group at 12 and 120 months, respectively, and 3.3+/-1.6 mm and 3.5+/-2.5 mm for the test group at 12 and 120 months, respectively). However, 120+/-6 months after GTR therapy, three infrabony defects (two controls and one test) had lost >2 mm of the attachment that had been gained 12 months after GTR therapy, and a statistically significant mean CAL-V loss of 1.7+/-1.3 mm was observed from 12 to 120+/-6 months in the control group. One tooth in the control group was lost between 60 and 120+/-6 months. The case series failed to show statistically significant differences between test and control regarding CAL-V gain 120+/-6 months after surgery. CAL-V gain achieved 12 months after GTR therapy in infrabony defects using non-resorbable and bioabsorbable barriers was stable after 10 years in 12 of 16 defects.

--- Columbus Blue Jackets right wing Cam Atkinson has been named the National Hockey League’s Second Star of the Week for the period ending January 31, the League and club announced today. All-Star Game Most Valuable Player John Scott was named First Star, while Buffalo Sabres center Jack Eichel was the Third Star selection.Atkinson tallied four goals and one assist for five points with nine shots on goal and a +4 plus/minus rating to lead the Blue Jackets to a pair of wins last week. He collected his third career hat trick, fired off seven shots and was +2 in a 5-2 home win over the Montreal Canadiens on January 25. The following night, he collected 1-1-2, two shots and was +2 in a 5-2 win at Montreal as Columbus swept the home-and-home set with the Canadiens.Atkinson has tallied 17-15-32 and 12 penalty minutes in 50 games this season and is tied for second on the club in goals, ranks third in points and has scored both of the Jackets’ two shorthanded goals this season. The Riverside, Connecticut native has registered 76-68-144 and 70 penalty minutes in 269 career games with the Blue Jackets. He was the club’s eighth pick, 157th overall, in the 2008 NHL Draft.The Blue Jackets return to action on Tuesday when they visit the Edmonton Oilers. Game time from Rexall Place is 9 p.m. ET. Live coverage on FOX Sports Ohio begins with the Blue Jackets Live pre-game show at 8:30 p.m. The game will also be broadcast live on the Scioto Downs Blue Jackets Radio Network, including flagship station Sports Radio 97.1 The Fan, and online at BlueJackets.com

[A case of lung adenocarcinoma with coexisting G719X and T790M EGFR mutations in which erlotinib was effective for the treatment of leptomeningeal carcinomatosis]. A 68-year-old man was referred to our hospital because of an abnormal chest shadow. Adenocarcinoma was detected using percutaneous needle aspiration cytology from the left supraclavicular lymph node. The patient was diagnosed as having primary adenocarcinoma of the lung(cT1bN3M1b: BRA OSS). Exon 18G 719X and exon 20 T790M mutations of the EGFR gene were detected in the same specimen. For first-line chemotherapy, four courses of cisplatin plus docetaxel were used. The primary lesion and a brain metastasis were reduced after the first-line chemotherapy. About four months later, he developed a recurrent brain metastasis and leptomeningeal carcinomatosis. He was treated with erlotinib(150mg/day)after wholebrain irradiation. The leptomeningeal carcinomatosis findings on a head CT image and the patient's consciousness disorder improved after treatment. EGFR-TKI therapy was effective in a case with leptomeningeal carcinomatosis, and coexisting EGFRsensitive and EGFR-resistant mutations.

A key part of most electronic commerce solutions involves the ability to quickly locate products and services and tailor content to each individual user or customer. This requires both product indexing and user profiling. There are many search engines and knowledge management tools, but none of these are built using the Enterprise Java Beans architecture. The present invention provides a mechanism by which a searchable product inventory can be matched with a customer's preference. It does so in a way that is simple for the programmer, scalable in design, and built upon an open systems architecture. Normally search engines require a large amount of memory space to execute efficiently. This algorithm is designed to take advantage of the object caching built into the underlying platform such that it has a smaller footprint. Normally search engines count the number of instances of words in html documents and then cross reference, by word count so that documents with the most number of word matches can be quickly found. The Advisor indexes the items in the various catalogs and makes them searchable by quality strings. The present insertion has combined these two mechanisms into a single integrated solution called the Advisor or the Shopping Advisor component, which can be part of a suite of Enterprise Java Beans components that enable the rapid deployment of eCommerce Web Sites. For example, other components in the suite can provide support for the management of user sessions and creation of customer orders.

Many fields of science require the monitoring of analyte concentrations in fluids. In an example of insulin-treated diabetes, afflicted persons must frequently monitor their blood glucose levels in order to appropriately ascertain the dose of insulin. Without an accurate measurement, insulin dosing would be dangerous. Multiple devices have been devised for the measurement of analytes in fluid. Devices such as electrochemical sensors utilize electrodes coated with polymer membranes. The functions of such sensors can be manipulated depending on which materials are used and in what quantities so that necessary reactions are controlled. Depending on the reaction near the electrodes, changes in current can be measured and thus correlated to the analyte of interest. The measurement of glucose in human blood makes use of electrochemical sensors. Sensors of this design measure blood glucose from samples drawn from a patient. In the case of diabetic patients, these samplings often occur several times per day. The sampling process, which equates to a finger prick, can be uncomfortable as well as difficult. Since blood sampling requires specially designed equipment, diabetic patients must have them readily available and thus carry their supplies with them at all times. Due to this cumbersome process, some patients fail to sample their blood as often as they should. Fortunately, an implantable glucose sensor would solve the problem of infrequent blood samplings. Current implantable sensor designs have many problems that must be addressed before such a device can come to market. Constant subcutaneous or vascular access must be attained for a sensor to constantly measure glucose levels. Due to discomfort and the possibility of infection, wires protruding from the skin are undesirable. A completely implantable sensor that communicates with an external receiver through wireless transmission would solve this problem. Unfortunately, an implantable sensor could result in internal trauma if the sensor is especially large or inappropriately shaped. Also, a patient's body could interpret an implanted sensor as a foreign object and attempt to either destroy or isolate it. If either of these actions were successful, the analytes of interest could not be monitored. Sadly, all attempts thus far have failed in the long-term due to these issues.

Electrostatic discharge ("ESD") is known to cause damage to electrical components and equipment. The prior art has developed certain ways to protect electrical equipment from human touch through specially designed user keypad panels. FIGS. 1 and 1A illustrate one such user keypad panel 10. Specifically, FIG. 1 shows a top view of keypad panel 10; and FIG. 1A shows a cross-sectional view of keypad panel 10. The upper-most layer of panel 10 is an embossed polycarbonate or polyester layer 11, which, for purpose of illustration, is shown transparent so as to view ESD screen layer 12. ESD screen layer 12 includes a silver-painted cross-hatch conductive pattern 12a that is connected to a conductive ESD tail 14. ESD tail 14 forms a mounting hole 16 used to electrically connect pattern 12a to equipment chassis. FIG. 1A shows further detail of keypad panel 10, including button switch 18, button spacer layer 20, signal trace layer 22, and adhesive layer 23. Layer 11 includes an embossed button pattern 11a-illustratively shown as a dotted line in FIG. 1 and as an upward protrusion in FIG. 1A. Button pattern 11a is adjacent button switch 18 so that human pressure on embossed button pattern 11a activates button switch 18 through deformation of ESD screen layer 12. Button switch 18 is known in the art and operates with signal trace layer 22 to generate signals--via switch circuitry 22a--indicative of switch activation. These signals are detected in signal layer 22 by known techniques such as through signal cable 24. Spacer layer 20 is used to form a space between ESD layer 12 and signal trace layer 22. Adhesive layer 23 bonds panel 10 to a flat surface associated with electrical equipment. Although keypad panel 10 is shown with only one button 11a, other buttons can be included. By way of example, button 11a can be a power on and power off button to the electrical equipment. In operation, a user operates the electrical equipment through keypad panel 10. Screen layer 12a arguably attracts ESD pulses which are in turn shunted, through ESD tail 14, to chassis ground associated with the electrical equipment. ESD tail 14 is mounted to chassis ground with a screw and nut through mounting hole 16. One problem with prior art panel 10 is that differential voltages can exist between lines of the cross-hatch pattern 12a, leaving residual voltage potential energy resident in ESD layer 12 even though other energy is drained off through ESD tail 14. Another problem is that panel 10 requires additional manufacturing cost and time due to ESD tail 14, and due to the nut and screw required to attach ESD tail 14 to chassis ground. Yet another problem is that ESD pulses are routed through a single location associated with panel 10, i.e., at ESD tail 14. One object of the invention is to provide a new and improved ESD keypad panel that reduces or eliminates the above-described problems. Another object of the invention is to provide an ESD protection panel with multiple ESD shunt contacts to improve grounding to equipment chassis. Yet another object of the invention is to provide an ESD protection panel that has improved ESD protection capability, as compared to the prior art, and which requires less cost and manufacturing time. Still another object of the invention is to provide an ESD-protected keyboard panel which has increased protection against ESD pulses coupling to associated electrical equipment. These and other objects will become apparent in the description that follows.

Incidence and duration of chemotherapy-induced nausea and vomiting in the outpatient oncology population. Nausea and vomiting are commonly recognized side effects of chemotherapy. However, the incidence and duration of these effects have not been systematically studied in a large outpatient oncology population. This survey was conducted over two consecutive 6-week periods in the adult oncology clinics of two university teaching hospitals. The objectives were: (1) to document the incidence and duration of chemotherapy-induced nausea and vomiting; (2) to identify variables that influence nausea and vomiting; and (3) to describe patterns of antiemetic prescribing and compliance. One hundred thirty-eight completed patient-maintained diaries were returned (70% response rate). Anticipatory nausea and vomiting were reported by 9.4% and 6.5% of patients, respectively. Fifty percent and 27% of patients reported nausea and vomiting, respectively, on the day chemotherapy was administered (day 1: acute nausea and vomiting phase). Percentages fell to 22% and 11% by day three and 14% and 2.5% on day 5. Of patients who reported nausea and vomiting during the five-day period, 52% and 33% experienced nausea and vomiting, respectively, during the delayed period only (days 2 through 5: delayed emesis phase). Emetogenicity of chemotherapy significantly influenced incidence and duration of those symptoms. Sixty-seven percent of patients reported taking antiemetics on one or more days during the survey period. Of patients who reported antiemetic use, 92% reported antiemetics on day 1, 51% on day 3, and 31% on day 5. At-home antiemetic use was related to the emetogenicity of chemotherapy received. Patients who receive moderate to strong emetogens as defined in this report should receive antiemetic therapy for a minimum of three days. Increasing the dose of antiemetic prescribed both in the clinic and at home may be of benefit.

Mucormycosis is a life-threatening infection that occurs in patients immunocompromised by diabetic ketoacidosis, neutropenia, steroid use, and/or increased serum iron. Because of the rising prevalence of risk factors, the incidence of mucormycosis has dramatically increased (1300% over 15 years according to one source). Despite disfiguring surgery and aggressive antifungal therapy, the mortality of mucormycosis remains >50%, and approaches 100% in patients with disseminated disease. Clearly new strategies to prevent and treat mucormycosis are urgently needed. Clinical hallmarks of infection by Rhizopus oryzae, the most common cause of mucormycosis, include the unique susceptibility of patients with increased available serum iron, the propensity of the organism to invade blood vessels, and defective phagocytic function, which we hypothesize to be, at least in part, a result of iron toxicity. These clinical hallmarks underscore the critical role of iron metabolism, as well as interactions with endothelial cells lining blood vessels, in the organism's virulence strategy. We have found that R. oryzae damages endothelial cells in vitro and this process is dependent on iron. Additionally, we have cloned the R. oryzae high affinity iron permease (rFTR1) which scavenges iron from iron-depleted environments such as is found in the host. Finally we have developed clinically relevant models of infection in diabetic ketoacidotic mice. We hypothesize that iron uptake, and specifically rFTR1, is essential for R. oryzae to cause infection. To test this hypothesis, we propose to: 1) characterize the mechanism(s) by which iron regulates R. oryzae- induced endothelial cell injury;2) construct an isogenic rftrl null mutant and its corresponding rFTR1 complemented strain jn R. oryzae by site directed mutagenesis;3) compare the pathogenicity of the generated rftrl to that of the wild-type and rFTR1 complemented strains in our in vitro and in vivo models of infection;and 4) elucidate the role of iron in regulating the innate host response to R. oryzae. Accomplishing these specific aims will define the role of the central elements affecting the establishment and progression of mucormycosis as it relates to iron uptake. Ultimately, a superior understanding of the pathogenesis of mucormycosis will enable development of novel therapies for this disease. Completion of the proposed studies will enable investigation of treatments that block R. oryzae uptake of iron.

Separation of polynucleotides is a focus of scientific interest, and numerous researchers have been attempting to achieve technical improvements in various aspects of polynucleotide separation. Anion exchange separation and reverse phase ion pair chromatography are among the most frequently used methods for separating polynucleotides. Previous work has focused on developing rapid, high resolution separations, developing separations based on the size of the polynucleotide fragment rather than the base sequence of the fragment, and on developing the ability to collect fractions of polynucleotides. W. Bloch (European patent publication No. EP 0 507 591 A2) demonstrated that, to a certain extent, length-relevant separation of polynucleotide fragments was possible on nonporous anion exchangers with tetramethylammonium chloride (TMAC) containing mobile phases. Y. Ohimya et al. (Anal Biochem., 189:126-130 (1990)) disclosed a method for separating polynucleotide fragments on anion exchange material carrying trimethylammonium groups. Anion exchangers with diethylaminoethyl groups were used by Y. Kato et al. to separate polynucleotide fragments (J. Chromatogr., 478:264 (1989)). An important disadvantage of anion exchange separations of double-stranded polynucleotides is the differing retention behavior of GC- and AT-base pairs. This effect makes separation according to molecular size impossible. Another important drawback of the anion exchange methodology is the necessity to use salts and buffers for elution, thus making subsequent investigation of the polynucleotide molecule fractions very difficult. U.S. Pat. No. 5,585,236 (1996) to Bonn et al. describes a method for separating polynucleotides using what was characterized as reverse phase ion pair chromatography (RPIPC) utilizing columns filled with nonporous polymeric beads. High resolution, rapid separations were achieved using an ion-pairing reagent, triethylammonium acetate, and acetonitrile/water reagent mobile phase gradient. This work is important because it is the first separation to give size-dependent, sequence-independent separation of double-stranded polynucleotides by chromatography. These separations are comparable to gel electrophoresis-compatible separations, currently the most widely used technology for polynucleotide separations. Bonn's work makes it possible to automate separations based on the size or on the polarity of polynucleotides. In the course of our work on separation of polynucleotides using the method developed by Bonn et al., with HPLC instrumentation and columns as described by Bonn, we discovered a degradation effect on the separation of double-stranded polynucleotides after long-term column usage (i.e., greater than about 50 injections). This degradation effect has been generally observed as a loss of resolution for base pairs greater than 200, as illustrated in the chromatogram of FIG. 1. As the degradation worsens, increasingly short fragments of polynucleotides are affected, as shown in FIG. 2. Eventually, the polynucleotides do not elute from the system. As such, the degradation effect or decreasing resolution appears to be a function of the length of the polynucleotide fragment being separated. There is no published chemical mechanism which would explain such a degradation effect that distinguishes between different size fragments while using reverse phase chromatography. Therefore, we first examined our procedure for packing the column. We realized that the molecules that we were attempting to separate were several magnitudes larger in size than those conventionally separated by reverse phase ion pair liquid chromatography. We suspected that hydrodynamic flow through the column was adequate for short polynucleotide fragments, but was being disrupted for larger fragments. In other words, perhaps the longest fragments were being partially sheared. However, we were unable to identify a packing procedure that would discriminate between short and long fragments of polynucleotides. Although we could not conceive a mechanism by which chemical contamination could produce these unusual results, we nevertheless examined contamination of one or more of the various "pure" reagents employed in liquid chromatography. After testing each of the reagents for contamination, we determined that this was not the source of the problem. This is not surprising, since the mobile phases used are not corrosive. Subsequent clean-up of the column with injections of tetrasodium ethylenediaminetetraacetic acid (EDTA), a metal-chelating agent, largely restored chromatographic resolution, as shown in FIG. 3. Putting a chelating additive into the mobile phase can provide some protection to the column. Without wishing to be bound by theory, there are several mechanisms by which a chelating reagent can provide protection or restore the instrument or column. One mechanism is the chelating reagent binds the free metal ions in solution, thus preventing any interaction of the metal ions with the DNA. Another mechanism is the chelating reagent coats colloidal metal ions, thereby preventing interaction of the colloidal metal ions with the DNA. The colloidal metal can be introduced from the mobile phase, injected into the mobile phase, or can be released from wetted surfaces in the fluid path. If the chelating reagent is water soluble, it can eventually dissolve the colloidal metals. We were successful in adding small amounts (ie., 0.1 mM) of tetrasodium EDTA to the mobile phase without significant changes to the chromatography. However, this concentration of EDTA was not sufficient to protect the columns in all of the stainless steel HPLC instruments and columns that were tested. There can be cases where the amount of metal ions present or generated are at a concentration where adding a chelating reagent will coat or bind the metal ions. In these cases, addition of a small amount of chelating reagent can allow the successful separation of DNA fragments. We tested the use of larger amounts of chelator additive in the mobile phase and found that addition of 10 mM of tetrasodium EDTA impaired the separation of polynucleotides. It was still uncertain that this higher concentration of chelating agent provided an acceptable protective benefit. While use of EDTA injected into the mobile phase (via the HPLC sample injection valve) demonstrated that the column can be regenerated, addition of chelating agents to the mobile phase is not an ideal solution to the problem as it can hamper subsequent use or analysis of the polynucleotide fragments. We then discovered that placing a cation exchange resin in the flow path of the mobile phase removed the problem. Guard disks were prepared containing a gel-type iminodiacetate resin with an ion exchange capacity of 2.5 mequiv/g (tested with Cu(II)). FIG. 4 shows a chromatogram obtained when the guard disk was positioned directly in front of the sample injection valve. FIG. 5 shows a chromatogram obtained when the guard disk was placed directly in front of the separation column (ie., between the injection valve and the column). Attempts to separate polynucleotides on the stainless steel HPLC system without the use of guard disks or guard columns containing cation exchange resin or chelating resin resulted in rapid deterioration of the chromatographic separation. From the improved results obtained by placing a cation exchange resin in the flow path of the mobile phase, we concluded that whatever was causing the peak distortion, probably ionic contaminants, was capable of binding to the cation exchange resin. Whatever was causing the fragment size-dependent distortion of the peaks had been removed by the cation exchange resin. Ionic contamination of the system can logically originate in one or more of several sources. The most significant sources of metal ions are HPLC components containing fritted filters made of stainless steel. Fritted filter components are used in mobile phase filters, check valve filters, helium spargers, mobile phase mixers, in-line filters, column frits, and other parts of the HPLC. Frits are commonly located at each end of a separation column in order to contain the particulate packing material within the column. The frit at the head of a column also serves to trap particulate material. Trapped particulate materials can be metal ions released from another part of the liquid chromatography system. The large surface area associated with any particular fritted component can contribute to faster solubilization of metals and release of ions. Thus, the ionic contamination from a fritted component can arise in at least two ways. First, the component can be a source of ionic material. Second, it can be a means for trapping ionic material. Ionic contamination from metals can exist in two forms. One form is dissolved metal ions. In another form, metals ions can exist in the colloidal state. For example, colloidal iron can be present, even in "high purity" 18 megohm water. Any metal or other ion that can interact with polynucleotides in the manner described could cause potentially harmful chromatographic effects when the metal becomes trapped on the chromatographic column. Magnesium and/or calcium and other ions can be present in samples such as PCR products. However, at the concentrations typically used, magnesium ions present in PCR products do not harm the peak separation. Metal ion contamination such as colloidal iron can be released from frits, travel to other parts of the HPLC and then be trapped. These types of contaminants will interfere with DNA in solution or after having been released and trapped on a critical component of the HPLC such as the column, an inline filter in front of the detector, or at a back pressure device located after the detector. In order to test our hypothesis that soluble metals and, potentially, other ions were causing loss of peak resolution during polynucleotide separations, we challenged the HPLC system with iron, chromium, and nickel. Known concentrations of these three metal ions were added to a polynucleotide standard (pUC18 DNA-Hae III digest). The polynucleotide/metal ion solutions were then injected into the HPLC. Chromium (III) ions (prepared from CrK(SO.sub.4).sub.2 did not degrade the separation when present in the sample at 9 mM. However, the sample contained 100 mM EDTA as a preservative against enzymatic degradation during storage, and much of the chromium could have been bound in an EDTA complex. However, when chromium was present at 90 mM, fragment size-ependent degradation of peaks occurred. At 900 mM chromium, no peaks could be detected. Several hours later, a sample containing 50 mM Cr(III) showed complete loss of the separation peaks. The same protocol using Ni(II) (prepared from Ni.sub.2 SO.sub.4) showed substantially no effect on peak shape, although some peak broadening was observed at 0.1 M Ni(II). With Fe(III) (prepared from FeNH.sub.4 (SO.sub.4).sub.2), the effect was less than with Cr(III). An injection of 900 .mu.M of Fe(III) in the polynucleotide standard showed no effect. However, an injection of 2700 .mu.M resulted in a loss of all peaks. There was some indication that the results were time-dependent, with the full effect becoming apparent several minutes after preparation of the metal/polynucleotide sample. The contact times and metal concentrations of the experiments described above were several orders of magnitude higher than would be found in a stainless steel HPLC system used for polynucleotide separations. Also, none of the experiments indicated how any reaction could be dependent on the size of the polynucleotide fragment. However, these data show the relative effect on separations of some of the metals found in stainless steel on polynucleotide separation. As an example of the effects of stainless steel, placement of a previously used stainless steel frit as an inline frit in front of the column resulted in no peaks being eluted from the column, even after short exposure of the frit to the fluid path. In this case all of the DNA was lost in the separation. This means that either DNA was taken up by the frit, or the frit released material that either disrupted the separation of DNA on the column or within the fluid path to the column and detector. The effect of metals on the reverse phase column separation of polynucleotides or an effect that discriminated according to fragment size has not been reported in the literature. There are, in fact, only a limited number of publications on the chromatographic separation of polynucleotides; most of which focus on single-stranded polynucleotides. Separation of single-stranded polynucleotides has been performed routinely by many workers, but this is usually on very short lengths of polynucleotide fragments (usually less than 100-mer, with 25-mer the average length), where, based on our observations of double-stranded polynucleotides, we would expect the degradation effect to be much less pronounced. Gunther Bonn and his colleagues have developed the world's leading chromatographic method for separating double-stranded polynucleotides. Bonn's work was performed on a stainless steel HPLC system with stainless steel hardware, including stainless steel frits. Based on our discovery, we concluded that the effect of metal contamination on polynucleotide separations was never reported by Bonn or others because the amount of dissolved and particulate metals in their stainless steel systems was below the threshold where degradation of the separation occurs and the systems worked adequately to produce good peak separations. Also, our work was carried out over a longer period, perhaps giving sufficient time for accumulation of contaminants within the system. Metal-free or titanium instrumentation is commonly used in protein separations, for reasons peculiar to the art of protein separation. For example, the activity of a protein can be affected if a metal is present. If the protein is intended to be collected and studied, separation is generally performed in a metal-free environment. Also, protein separations use particular mobile phases that can be corrosive to stainless steel HPLC equipment. Although metal-free or titanium systems are generally used in the separation of proteins for the reasons discussed above, it has been demonstrated that the use of metal-free or titanium systems is not necessary to maintain the integrity of the separation and that stainless steel HPLC systems show equivalent performance (Herold, M. et al., BioChromatography, 10:656-662 (1991)). In fact, Hewlett-Packard, one of the leading manufacturers of HPLC systems, now recommends stainless steel systems for use in protein separations. Because of the success of using stainless steel components in protein separations, and because the use of stainless steel systems for polynucleotide separations had been shown to be successful in the past, there had previously been no indication of the requirement to use non-metal or titanium system components for liquid chromatographic separation of polynucleotide fragments. Our subsequent experiments showed that even if titanium or PEEK fluid path components are used, then some treatment was necessary before the components could be used for Matched Ion Polynucleotide Chromatography. Although an improvement, our initial use of titanium frits did not give consistent results. Treatment of the frits with dilute nitric acid and then with a chelating agent did improve the performance of the instrument. Similarly, as shown in the examples, PEEK frits were not consistently suitable for MIPC, but acid treatment did improve their performance. Finally, degassing the fluid before it enters the liquid chromatography system removes the oxygen. This process will inhibit the oxidation and production of metal ions in stainless steel or titanium or other tubing containing iron. The use of a degasser to remove oxygen can help the MIPC separation. This is probably because the need for an ion contaminant free fluid path is much more critical in MIPC than in prior art separation processes. The use of the precautions of the method and system of the present invention has been found to be much more critical for double stranded DNA than for single stranded DNA separations. As Bonn and coworkers demonstrated, stainless steel can be an excellent material to be used for the fluid path of DNA separations. However, it is difficult to keep the stainless steel surface free of contaminants which interfere with MIPC, especially as the surfaces age.

"As I tried to kiss you, as if to avoid me with your T-Shirt on, you dove into the shining sea..." "The white flower petals on your soaking skirt..." "Spread open upon the surface of the blue water." "Tell me why, when you winked..." "Oh Baby, Tell Me, Tell Me" " You're unpredictable..." "'Tell me you love me, Tell me that you need me..." "Tell Me, Tell Me, ...my Angel of the Summer..." "'Tell me, lover, Tell me that you need me..." "Oh Baby, Tell Me, Tell Me - I know that you're in love..." "'Tell me you love me, Tell me that you need me..." "Tell Me, Tell Me - but you're a mystery." "Thank you for waiting..." "Darling." "Oh gosh!" "This is more than I can stand!" "Don't Cry Jingoro!" "The Heat of Young Love." "Anju!" "Zushio!" "Mother!" "Mother!" "I promise that I... that I shall find you, Mother, without fail!" "I shall!" "Say..." "What's got you all excited?" "Oh, noth..." "Wherever did you find that book?" "Geez!" "It's the only thing that'll make Kazuya fall asleep!" "Oooh!" "I don't care anymore, nope!" "Jingoro hasn't been behaving at all!" "I wonder what's happened..." "What's up with you kids?" "Is something wrong with Jingoro?" "Y'know, Kazuya's finally fallen asleep, after much effort on my part!" "He doesn't listen to me at all!" "Can't you talk a little more quietly?" "!" "Yeah!" "Can you believe it?" "!" "It was a huge hassle just getting him back home!" "It's just a thought, but... maybe Jingoro's entering puberty?" "The onset of puberty..." "Indeed, even I could see... that he wasn't our usual Jingoro." "But, even then..." "Hey!" "Jingoro, quiet down!" "Oh, your Auntie has things to do tonight so Kazuya will be staying over in Kyosuke's room." "Kazuya took advantage of the fact that Auntie was out..." "Okay..." "Here it comes." "Okay." "Still, tell me what happened?" "Your cutesy eyes are all red." "Oh!" "Well..." "Nothing much, really." "Though, I'm concerned about..." "About Jingoro?" "Uh-huh." "There's gotta be something wrong with him." "He's never disobeyed Kurumi and Manami like that before." "That's true." "That must mean that..." "that..." "Oh!" "...that, just like your father was saying..." "Huh?" "Then, that means well, Jingoro is a he, after all... so so the "onset of puberty" must be something that just happens naturally... so..." ""Something that happens naturally?"" "At that moment, I realized that I had just said something quite racy right in front of Hikaru." "H..." "Hikaru..." "O..." "Oh, Darling!" "Huh?" "!" "W..." "Well..." "Well..." "H..." "Hikaru!" "Umm, I need to take care of something first!" "Gosh, Darling!" "Darling is using Jingoro as an excuse!" "The truth is... that it was you who... who that it was you who desired me!" "Oh, dear God!" "I've..." "I've been dreaming all this time..." "About..." "About that moment." "Tell me that it's... okay for us to..." ""It's all right."" "Yeah right!" "Oh, this is too much!" "Though if it's going to be on the Nurse's bed well, that's a bit different from how I'd imagined it." "N..." "N..." "Nurse's Room?" "!" "Thank you for waiting..." "Darling..." "Oh?" "Yesterday evening, huh?" "Uh-huh." "She was shaking..." "terrified because a truck splashed through a puddle and drenched her." "When it comes to animals, you've got such a big heart." "He's so cute!" "Gosh, Hikaru... go easy on me, won't you please?" "Oh!" "Sorry about that." "But, my goodness, Kasuga!" "Just look at your face!" "Huh?" "Er..." "Well..." "Quite an injury, considering you were only scratched by a girl..." "G..." "Gee, Ayukawa!" "Anyway, about Jingoro..." "Hikaru told me about him." "Maybe he's lonely." "Jingoro, that is." "What?" "I mean, when you and your sisters are at school Jingoro is all alone by himself, isn't he?" "Being all by yourself... it gets quite lonely, you know." "Being alone..." "A..." "Ayukawa!" "S..." "So, y'know... just think of it as doing me a favor!" "So... help me out here!" "I hear ya!" "I hear ya!" "You want us to find Jingoro a pussycat, one that he'll like, right?" "Trust us, I say!" "Here!" "Yeah!" "Whoa!" "Hey, guys!" "What are you up to?" "!" "Pussycats!" "Pussycats!" "We can pick from a wide selection here!" "Look, you, don't you know that puberty and the estrus cycle are when we've got to fight using reason!" "I'm gonna fight!" "Wh..." "What the heck's this?" "!" "Hey!" "Why, you, you knew about this, didn't you?" "!" "Correctamundo!" "Oh, Kurumi and Manami are in there too!" "Wh..." "What?" "!" "A guy!" "Eyeeeww!" "Shoo!" "Shoo!" "You pervert!" "Yo, Hatta!" "Watch it!" "Watch it!" "Uh..." "Uh-oh!" "Hey!" "What the...!" "K..." "Kasuga!" "Help me out here!" "Help!" "I'm suspended, man!" "What?" "!" "What do you mean "help me..."" "Gimme your shoulders!" "Your shoulders!" "Shoulders!" "Shoulders!" "Will you calm down..." "Hey!" "Hey!" "Hurry!" "Help!" "Whoa..." "I'm saved!" "You take it from here, man!" "There's another one still out there!" "Oniichan!" "You're scum...!" "Hey!" "Hey, Oniichan!" "Don't hold him so tight!" "You're hurting him!" "Relax!" "Relax!" "We're doing this for Jingoro's own good." "Listen, Jingoro... we'll get you feeling great in no time!" "Hey, Kasuga!" "Over here!" "Over here!" "Huh...?" "Komatsu and Hatta..." "Just what're you trying to do, Oniichan?" "Matchmaking!" "Matchmaking!" "WHAT?" "!" ""To want somebody who'll be there always..."" ""That's not so strange, is it?"" "Ayukawa..." "Every time I'm here, your house is always so nice, Madoka!" "What do you mean?" "I mean, it's so spacious!" "If I do some aerobics at home I can't avoid kicking my dad's butt!" "Say, Madoka, have you decided on what to name this cat?" "Nope." "Not yet." ""Kyosuke!"" "Not gonna happen, or will it...?" "!" "Of course not!" "This cat's a "she," you know." "So that's that!" "Maybe it's not so bad an idea..." "A girl with a boy's name." "Tumtatatum! "When you meet someone for the first time..."" ""...sometimes love blooms, starting that very day!"" ""The stranger that you are..."" ""...and the stranger that you are..."" ""We'll set you up on a date..."" ""Meow-Meow With A Punch!" -"Meow-Meow With A Punch!"" "I'm your host, Komatsuya lwashi!" "I'm the assistant host, Hattatei Buri!" "All right, our first contestant..." "Okay, please state your name and age;" "let's hear some energy!" "Your name and age are...?" "S..." "Say, young man, how old are you?" "Doofus!" "Whatta li'l friggin' twerp!" "Why you little punk, you think you can diss me that way, dammit?" "!" "Well, well, please, calm down." "Calm down!" "All right now, time for a meeting!" "Okay!" "No-go!" "No-go!" "Next, please!" "This sure is something, to have this much of a response!" "For something done by Oniichan, it's pretty impressive, I think." "Stop!" "Hey!" "Kazuya!" "That's right!" "Uh-huh!" "You shouldn't be naughty like that!" "Look who's talking!" "I'm not gonna pull Kurumi and Manami's skirts up for you guys anymore!" "ShShShShhh!" "Why, you guys!" "All right, this calls for..." "Wh..." "What are you doing, Oniichan?" "!" "Just come with me!" "You're hurting me!" "What's up with him?" "!" "I didn't know he was into child abuse." "Huh?" "Er..." "Oh, no, nothing." "What?" "!" "You want me to switch places with Jingoro?" "!" "Yeah!" "That's the only way we can find out what's troubling him!" "Okay?" "I'm begging you!" "No way, I'm not gonna!" "Why, you!" "Don't you feel any sympathy for Jingoro?" "!" "He could be heartbroken because he's all alone!" "Jingoro's all alone?" "Yeah." "Oniichan!" "Oooh!" "Here comes the snowman!" "Huh...?" "!" "Oh!" "It's so cute!" "Ah... but I dunno, maybe not for her..." "It doesn't look like they'd go well together." "Like, whassup?" "!" "What are you lookin' at?" "!" "Don't you "whassup" me!" "We've been lookin' for that cat, y'know." "We know all about your type, babes that claim they found things, when really they ripped 'em off!" "Say what?" "!" "Hey!" "Hey!" "Jingoro!" "Hey!" "Jingoro!" "A white one and polka-dotted one!" "Who said he's feeling down?" "!" "Uh-oh!" "Oniichan!" "What's the meaning of this?" "!" "Um..." "Well... so this is what happens when Kazuya becomes a cat." "Er..." "Oh, nothing!" "At any rate, about Kazuya I mean, about Jingoro..." "Jingoro!" "Huh?" "Er, I mean, Kazuya is gone!" "Oh, gosh!" "He's so irresponsible, leaving his friends like that!" "Oh, no!" "H..." "Hey, Kasuga!" "What's up with Oniichan?" "Bumble, Bumble!" "Bumble, Bumble!" "Bumble, Bumble!" "Jingoro!" "Hey, Kazuya!" "Where did Jingoro go?" "!" "Hey, Kazuya!" "Will you help me out a little?" "!" "Madoka's cat?" "What?" "Oh, er... that was, y'see my mommy!" "What?" "!" "Er... just what's going on here?" "Yesterday, quite by accident, while I was out shopping, I saw her!" "There's no doubt about it!" ""Jingoro!" "What's wrong?" "!"" "Please!" "Tell me!" "Where did she go?" "!" ""Tell me?" Um..." "I've got no idea what's going on here, you know what I mean?" "Well, if you're looking for Madoka, then..." "she called earlier and said..." "Why, you, Jingoro!" "Where'd you go?" "!" "I've been looking everywhere for you!" "So what's the story?" "!" "Are you telling us that the cat's owner is here?" "What a cute one." "My!" "Two pussycats at that." "Madoka..." "So, you're the one... the weirdo who lets us take care of his cat and then accuses us of stealing her." "We sure would like a little gratitude for finding her!" "What you did was despicable!" "You won't get away with this." ""I hear they are a shady bunch of fellows."" ""If I recall... they hang out just outside of town."" ""So, what happened to Ayukawa?" "!"" ""Oh!" "Oh, she went with Hikaru!"" ""What?" "!" "Hikaru too?" "!"" "Mommy!" "Such an energetic pussycat." ""Puttytat, Puttytat... won't you be my... friend?"" "If you thought that all the girls these days would be so easily intimidated you're totally mistaken!" "Ayukawa!" "Sempai!" "Mommy..." "Mommy!" "Mommy!" "Oh no!" "There!" "Now, just what's going on here, Kasuga?" "!" "Wh..." "Oh, er..." "Well, you know..." "like they say, "Cats ought to be with other cats!"" "What?" "!" ""Mommy!"" ""Mommy!"" "Who knew that it was just an accidental resemblance..." "An accidental resemblance among cats?" "!" "Keep your chin up, okay?" "Until you find her Ms. Madoka here will take care of you like a mother would." "Ayukawa..." "Oh!" "I love Jingoro too, you know!" "Jingoro!" "At that moment..." "I felt really envious of Jingoro..." "Broken Heart is in Flames. "It began in the summer..."" "Hold me, Hold me, Hold me, Fire Love. "It burnt up in the fall..."" "Broken Heart is in Flames. "It's withering in the winter..."" "Flare, Flare, Flare like the Sun, Fire Love..." "On that last night we went out for a drive, I left my go-out voice behind." "As we watched the horizon, I said good-bye." "Like seasons, hit songs come and go..." "As you get used to one, you're tired of it..." "That's what's written on your profile." "You were waiting for the lucky star in your room I was too late to notice it in that one phone call that day." "Broken Heart is in Flames. "It began in the summer..."" "Hold me, Hold me, Hold me, Fire Love. "It burnt up in the fall..."" "Broken Heart is in Flames. "It's withering in the winter..."" "Flare, Flare, Flare like the Sun, Fire Love..." "Erase the memory of you from me... "Stop, Stop, Stop."" "Kurumi 's fallen in love!" "That royal pig has lost her appetite and gotten all mellow and sentimental, gazing at the night sky!" "Exactly who did she fall for?" "!" "What?" "!" "Hayami, the guy from the Soccer Club?" "!" "Why, that's the guy who sent Ayukawa a love letter!" "Next time: "A Tender Little Story!" "Kurumi's First Love" " Chapter 'Hell'"" "I... am in for one surprise after another!"

1. Field of the Invention The present invention relates generally to animal retrieval devices, and, more particularly, to a pet identification and retrieval device. 2. Description of the Related Art Pets are a beloved part of many family homes. The warmth, company and affection which they provide is well known. After all, it is said that dogs are man's best friends. Sometimes, however, that relationship between human and animal is threatened by the disappearance of the animal from the home. This can happen in a number of ways. The animal may be an outside animal, such as a dog or cat, which strays from home and gets lost. Such animals often end up at animal shelters or dog pounds. If the family has moved into a new neighborhood, it is likely that the family pet could get lost in its new surroundings. Even for indoor pets, there is a chance of the animal being lost, since many animals like to sneak out of a partially open door. Even with attentive and caring owners, the possibility of a lost pet exists. In this event, it becomes paramount that individuals who find the animal have a simple and effective means to identify the animal and contact its owner. The previous art includes numerous dog tags. Examples of this type of device include U.S. Pat. No. 4,137,660, issued in the name of Dettmann et al., U.S. Pat. No. 4,091,766, issued in the name of Colliard, and U.S. Pat. No. 3,585,743, issued in the name of Jeffers. These dog tags usually include metal tags engraved with information regarding the animal, or an identification card with written information stored in a plastic sheet located on the collar. These devices suffer from one or more of the following problems. First, dog tags provide limited space for information on the animal, such as what the animal likes to eat. This is important if the animal must spend the night at the individual's home who found the animal. Second, when the family moves or goes on vacation, the tag must be replaced with a new tag that contains the new address and phone number. Third, the metal tags have a tendency to rust over time. Fourth, the engraved information on the metal tags has a tendency to wear down and become unreadable. Fifth, the tag does little to facilitate calming the animal, other than providing the animal's name so that the individuals who found him or her can use the correct name. Sixth, the paper tags are affected by moisture in the air, such as when the animal is outside in the rain. Such moisture can make the written information unreadable. U.S. Pat. No. 5,355,839, issued in the name of Mistry, discloses a retrieval device that incorporates a micro cassette recorder into a collar. The problem with the '839 device is that the microcassette can get damaged in the rain or if the dog comes near a magnetic source. Also, the '839 device requires that the individual finding the animal have a micro cassette player to listen to the message and discover the animal's name and its owner's identification. This severely limits the effectiveness of the device. Digital recorders exist in the previous art. Examples include U.S. Pat. No. 4,815,032, issued in the name of Fujii, U.S. Pat. No. 4,772,873, issued in the name of Duncan, and U.S. Pat. No. 3,430,256, issued in the name of Goodman. In general, such devices are bulky and too large to be used with a dog or cat collar. Such digital technology must be miniaturized so as to fit on a dog or cat's collar. One device, being sold on the market, incorporates solid-state technology to digitally record a message to be replayed by the individual finding the animal. There are several problems with such a device, however. First, the device is bulky, heavy and cumbersome, making it effective only with bigger animals, such as large dogs. Cats would find the device bulky and uncomfortable. Second, the device is an elongated, hanging from the animal's collar. This swinging motion would be distracting to pets. Also, the swinging motion would increase the chance of the device getting caught on some object and choking the animal. Third, the attachment point for the device to the collar is extremely weak, increasing the risk that the device would inadvertently break free while being worn. Fourth, the device requires that the back plate be removed to record a message. This is difficult for many individuals, such as the young, the elderly and the infirm. Also, whenever the family moves, or takes the pet on vacation, the device must be opened to record a new message. This is a difficult problem given most families do not have the minuscule screw drivers necessary to open the back plate. Fifth, there is no way for the owner to know if the battery is operational, unless the owner opens up the device and tests the battery with electrical equipment. A search of the prior art did not disclose any patents that read directly on the claims of the instant invention. Consequently, a need has been felt for providing an apparatus and method which overcomes the problems cited above.

This invention related to shoulder supports and is more particularly directed to an acromioclavicular support for humans, particularly useful in treating and retaining in position most degrees of ligamentous ruptures. Typically, there are three degrees of acromioclavicular (hereinafter referred to as "a/c") sprains: (1) first degree, where there is a very slight tearing of the a/c ligamentous fibers, resulting in localized pain over the a/c joint; (2) second degree, where there is a greater tearing of these a/c ligaments and greater disability and more substantial pain upon motion; and (3) third degree, where there is severe ligamentous sprain in which one or more of the ligaments have been completely ruptured or torn, and there is dislocation of the clavicular. In each of these degrees of a/c sprain, the clavicle is in misalignment with the acromion and the ligaments therebetween are injured, from mere misalignment of the first degree, where there is slight separation but the shoulder parts are still co-planar, to the second degree, where there is partial separation and the clavicle and acromion are out of alignment and the shoulder parts are no longer co-planar, and to the third degree, where there is complete separation and misalignment of the clavicle and the acromion. Frequently, these conditions, which often result from sports injuries, are treated surgically, because treatment requires long term healing, and sometimes relatively complete immobility, for six weeks or more. Such surgical procedures often result in a stiff shoulder because a pin is inserted in the shoulder joint or a fusion of the joint is made to hold the a/c in position relative to the clavicle. Only careful and patient tending to these injuries can allow recovery, because of the need to immobilize the shoulder during healing and to apply specific pressure to the a/c for a relatively long term. Known supports do not have the ability to draw the a/c to the clavicle. Such supports may be too high on the shoulder or they may slip out of position or they are not suitable for long term wear or they apply improper pressure to one side or the other of the joint. The support embodying the present invention provides a firm fixation of the a/c articulation and retains the a/c dislocation and its sprain in anatomical apposition. Such a preferred support will maintain sufficient pressure upon the a/c separation to retain the sprained area in healing configuration. The preferred support will not immobilize the shoulder girdle completely or as a result cause atrophy and weakness of the girdle muscles to occur during immobilization. A preferred a/c support following the teachings of the present invention has an abdominal belt and straps, one end of each of which is slidably connected to the belt, which rise from the front and rear sides of the belt and are adjustably secured to a pad dimensioned for covering the a/c joint, and the free end or distal portion of each strap is secured to the belt by means of an adjustable buckle spaced apart from the other distal strap slidable connection end. Through such a device, the pad is maintained under sufficient pressure to heal the a/c joint, because the straps may be adjusted to properly distribute belt pressure upon the shoulder pad and to provide tension of the shoulder pad upon the separated a/o articulation and retain its apposition. The support embodying the present invention is not for use on a fracture of the clavicle or for sterno clavicular separation, but is intended for use strictly in a/c separations where distributed downward pressure and tension from the front and rear of the patient can promote healing of the a/c joint. Adjustable straps also permit the strap lengths to be changed as necessary for use with patients of greater or lesser height or more or less abundant structure, giving the support embodying the present invention great versatility for reuse by different persons.

In April 2017 we had the privilege to do a spring bear hunt with the Absaroka-Beartooth Outfitters in Big Timber. Our two awesome and hardworking Wounded Warriors were Josh Beckett and Dean Murray. These two Warriors were excited to get this opportunity to bag their first bear. Before the week long hunting trip even started, Dean went out scouting with one of the guides to just see the huge abundance of elk in the hills and they drove right up on a gorgeous cinnamon sow crossing the road. Dean hopped out and positioned himself to get a shot on the bear before she spotted them. She did indeed spot them and scattered to a brush pile and stood up, but Dean was ready for her and made a great shot to drop her without a problem. With a very pleased guide and a very excited Warrior, they loaded up the bear to bring back to the lodge and tell their story. This was a great bear and tested to be very old. With one Warrior tagged out before the second Warrior even had shown up for the hunt, we were doing pretty good. Josh showed up and had all the work cut out for him, or so he thought. The very next day of hunting had a little surprise. There were over ten inches of snow and a cold weather front was forecasted to stay for his week of hunting. That didn’t stop Josh or his guide. For six straight days of 12-16 hours of walking and spotting in the cold wet winter weather, Josh never quit or gave up as not one bear had presented itself in this weather. On the last evening of the last day, just before dark, Josh headed into the Timber to walk down a hillside. Just at that moment, a quick flash of a big black bear ran out in front of Josh about 100 yards and stood up only presenting a partial face. With very little light, Josh pulled up and fired at the big black bear. The bear disappeared and we searched for any sign of a hit, but could not find anything and another storm was quickly moving in. The guide and Josh went another day looking for the bear but with several inches of fresh snow again, they could not find any sign that the bear was hit. Josh was disappointed but had an absolute amazing time and would not admit failure. It was a great trip that was one of the most challenging trips we have experienced but was well worth the experience to see these great Warriors thrive. Great job Josh and Dean, and a huge thank you to our outfitters.

The invention generally relates to superconducting magnets, and more particularly to superconducting magnets with an improved support structures for supporting superconducting coils. Superconducting magnets are used in many applications, such as magnetic resonance imaging systems and cyclotron magnet systems. Superconducting magnets generally have a plurality of superconducting coils for generating a magnetic field and one or more support members for supporting superconducting coils. The “superconducting coil” is referred to as “coil” hereinafter for simplicity. When the superconducting magnets are energized, the coils produce axial electro-magnetic (EM) forces and radial EM forces. The one or more support members are used for supporting the coils against the axial EM forces. The radial EM forces are generally accounted for by the coils' own hoop stresses, which result in hoop strains and radial expansions in the coils. Such radial expansions of the coil can cause frictional movements at the contact interfaces between the coils and the one or more support members. The frictional movements generate heat, which can quench the coils and lead to magnet instability of the superconducting magnets. This is particularly noticeable at low temperatures, such as liquid helium temperature, since the coils have very small thermal capacity and a small thermal disturbance can raise the temperatures of the coil to exceed its threshold, causing the coil to quench. Some conventional superconducting magnets allow some frictional movements at the contact interfaces by having more superconducting or normal metal materials in the coils to absorb the thermal disturbances. However, superconducting materials are expensive and adding more material in the coils results in the increased production cost. In another conventional superconducting magnet, the coils are directly bonded to the support structure. The bonding strength at bonding interfaces makes the one or more support members move together with the coils. However, inconsistent movements can cause cracks at the bonding interfaces, which results in thermal disturbances to the coils. Therefore, there is a need to provide superconducting magnets with an improved support structure to achieve better magnet stability.

The late Michael Suleiman and others have argued that Arab American identity was formed as a result of negative portrayals of Arabs and strong pro-Israeli bias in the U.S. media during and after the 1967 Arab-Israeli War. Certainly, the media acted as a negative motivating force behind the solidification of an ethnic “Arab American” identity and was key to the formation of a handful of key community organizations, such as the Association of Arab-American University Graduates (AAUG). In AAUG publications and scholarly sources in the 1960s and ‘70s, the founders and founding members of AAUG distinguished between the “recent arrivals” and past generations from the Middle East in the U.S. They mostly framed these differences in terms of transnational politics, demographics, and ethnic identity; claiming a pan-Arab, secular nationalism as opposed to religious, ethnic, village based identities popular among earlier generations of immigrants from the Middle East. The two groups, however, were not so clearly defined into oppositional binaries. This paper will examine how Arab immigrants reflect on the period 1945-80 in memoirs and autobiographies, and how they related to the politics of “homeland” through emotional and financial connections with ecclesiastical structures, Islamic organizations and states in the region. The sources for this project will be AAUG publications, including memoir-articles in Arab Studies Quarterly, biographies and autobiographies published in the 1970s and 1980s as well as materials from the Antiochian Orthodox Church and the Washington Mosque Foundation.

Traders can use arbitration techniques to make a profit out of the rate difference between the 2 markets, with very little risk. A Fx arbitration refers to making make use of of a state of inequality between markets, where a trader can make use of the difference of a decided currency in one market with another to obtain gainings by purchasing the currency at a bottom rate market and trading it off at a higher price market. A supply including 2 currencies is a plain arbitration supply, as long as distribute involving 3 or more currencies is a complex arbitrage deal. It is significant to note that not everyone currencies are introduced for make use of in a Fx arbitrage trade; depending upon the country as well as the Fx market itself, certain currencies may as well as may not be entertained for Forex arbitration trades. Forex arbitrage review is an extremely important personality in starting point your on the internet trading strives. A Trading robot is a software program that automatically enters and escapes trades in the forex market with the intent of turning a profit. Fx arbitration computer will help seem whether a special scheme is coming to provide the required profits as well as not. A Forex arbitrage calculator are sold for a fee on a great amount of Sites by both third parties and foreign exchange brokers; and also is offered for free as well as for trial by a number of upon opening an account.

The present invention relates to novel methods for predicting suicidal and other abnormal behaviors. In particular, it relates to the detection of polymorphisms in the tryptophan hydroxylase gene, which are correlated with abnormal serotonergic function and related behaviors. Genetic factors have been implicated in the etiology of alcoholism, violence, and suicide in both family and twin studies. A strong interrelationship exists between these phenotypes, as they tend to occur in the same individual and in individuals who are genetically closely related. Although these disorders are heterogeneous in their clinical expression, and have complex causes, it is possible to identify more homogeneous subgroups among patients with these problems. Decreased brain serotonin concentration has been associated with several behavioral traits including impulsive, aggressive and suicidal behavior, pyromania (fire setting), and with disruption of circadian rhythms. For a review of the correlation between serotonin concentrations and abnormal behavior see, Lopez-Ibor et al. (1991) In Serotonin-related psychiatric syndromes: clinical and therapeutic links (Ed. Cassano and Akiskal, Royal Society of Medicine Services Ltd.) pp. 35-40. Serotonergic activity is correlated with the concentration of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid (Asberg et el. (1976) Arch. Gen. Psychiatry 33: 1193-1197). Low concentrations of 5-HIAA in the cerebrospinal fluid (CSF) have been associated with behaviors characterized by intolerance to delay, or impulsive behavior. These include impulsive aggression (including homicide), pyromania (fire setting), personality disorders, and alcoholism. Serotonin is also critical in slow-wave sleep, temperature control, and appetitive behaviors. Diminished CSF 5-HIAA concentrations have been found to be associated with risk of suicide in depressed patients. In animal studies, indices of decreased serotonin concentrations are connected with postulated anxiety-related intolerance to delay and deficient control of impulses. Although 5-HIAA concentrations in CSF are correlated with abnormal serotonergic behaviors, 5-HIAA's usefulness as a marker is limited by the difficulty in obtaining CSF. CSF may only be obtained by an invasive, expensive, and impractical procedure. Thus, there is a need for an easily typed marker that is correlated with 5-HIAA levels and abnormal serotonergic behaviors. The present invention fulfills this and other needs.

DESCRIPTION (Applicant's Abstract): Cocaine amphetamine, and other psychostimulant drugs, cause abuse and addiction by interacting with and altering certain neurochemical systems in brain. Recently, a neurochemical has been discovered which appears to be involved in cocaine's action. This neurochemical has been named CART (fro Cocaine and Amphetamine Regulated Transcript). The goal of this proposal is to clarify how CART peptides mediate or modulate the effects of cocaine and other psychostimulant drugs. A first step in this work is to show that injection of these peptides into the brain causes the same physiological effects that are caused by cocaine. In other words, CART peptides cause increased locomotor activity in rodents and reduced food intake. These are well known effects of the psychostimulant drugs themselves. In addition, we will look at the effects of these drugs at brain receptors; stimulation of physiologic receptors in brain is known to produce second messengers molecule such as cyclic AMP. Further, we will map the distribution of CART peptides in brain so as to fully understand where they are located and how they might influence the brain. We will also look at the effects of blocking their production and availability so as to obtain additional evidence about what they do, and we will prepare to make transgenic mice which either overproduce or have no CART peptide. These experiments will help us to understand how cocaine changes the brain, will show us how these new neurochemicals, the CART peptides, are involved in drug abuse, and may provide new strategies for developing medications to treat cocaine abuse and dependence.

Are in vivo gastric bioadhesive forces accurately reflected by in vitro experiments? Bioadhesive polymers have been used in oral drug delivery to prolong the contact of dosage forms with the site of drug absorption. Previous investigators have coated oral dosage forms in polymers that demonstrated bioadhesive properties during in vitro screens in efforts to prolong the gastric residence of drugs absorbed only in the stomach and proximal duodenum without clinical success. To further investigate the bioadhesive properties of the gastric environment, an in vivo quantitative bioadhesive fracture strength test was developed. Bioadhesive and non-bioadhesive bioerodible polymers with potential for use in oral drug delivery were tested for bioadhesive fracture strength both in vivo and in vitro. Surprisingly, no statistically significant difference was found between the bioadhesive fracture strength of fast eroding polyanhydride and slowly eroding hydrophobic polymers in vivo. When the same polymers were tested in vitro, the expected difference was observed. The lack of IVIVC (in vitro/in vivo correlation) among bioadhesive fracture strengths reflects the clinical finding that polymers that produced strong bioadhesive forces in vitro may not achieve prolonged gastric retention in vivo due to differences between the in vitro screening conditions and the in vivo bioadhesive environment.

Organic ester compounds are good solvent widely used in synthetic resin industry, such as for paints, inks, adhesives and detergents. At present, ether compounds are mainly divided into two categories, i.e. E series and P series. The E series of ether compounds are obtained from the synthesis of alcohols and ethylene oxide while P series of ether compounds are obtained from the synthesis of alcohols and propylene oxide. The related ester compounds thereof are primarily acetate esters, whereas no propionate ester products have been developed so far. In recent years, it has been found that the E series of ethers or acetate ester compounds thereof when inhaled into human body are likely decomposed into alkoxy acetic acid ether and in turn induce the erythrocyte becoming abnormal and thus toxic to the genital organ. On the other hand, P series would not cause these damages. At present, propylene glycol monomethyl ether acetate of P series is inferior to the solubility against unsaturated polyesters or polyurethane resins as well as the drying capability of the coating thereof. Therefore, it is urgently demanded to develop a kind of solvent having not only excellent solubility and drying capability but also low toxicity. Directing to this requirement, the inventors of the present application endeavored in positive research and development, and eventually produced successfully propylene glycol monoethyl ether propionate with best result.

There is an increasing demand for higher image qualities in image forming apparatuses, such as copy machines, laser printers, and facsimile machines. Particularly, in full-color printing applications, there is the problem of image displacement in multi-color images. A photosensitive drum used for forming an image by an electrophotographic technology is typically subjected to the processes of charging, latent image formation and development, image transfer, and cleaning by various units disposed around the photosensitive drum while the photosensitive drum is rotated. In order to achieve high image quality, an entire surface of the photosensitive drum needs to be uniformly charged and developed under uniform developing conditions. Because the photosensitive drum is rotated during such processes, the photosensitive drum is required to have a high runout accuracy (which indicates the amount of variation in the distance between a rotation center and a peripheral surface of the photosensitive drum). Generally, the photosensitive drum includes a cylindrical base of a metal, such as aluminum. On an outer peripheral surface of the cylindrical base, a photosensitive layer is provided. The cylindrical base with the photosensitive layer formed thereon may be referred to as a “sleeve member”. Further, flange members are attached to end-opening portions at the ends of the sleeve member in the axial direction thereof. The photosensitive drum is supported by, and rotated with respect to, an apparatus main body via the flange members and a shaft member engaged in axle openings provided in the flange members. Thus, the flange members need to be accurately and securely attached to the end-opening portions of the sleeve member. In order to achieve a smooth and accurate rotation of the photosensitive drum, the axle openings in the flange members need to be aligned with the central axis of the sleeve member at all times. Further, in order to allow the photosensitive drum to be rotated smoothly and without error, the flange members need to be prevented from idly rotating with respect to the sleeve member or being detached therefrom. For these purposes, the sleeve member and the flange members are typically assembled by press fitting (in combination with an adhesive, as needed). In comparison with the base of the sleeve member, the flange members generally have lower rigidity. As a result, the flange members may be deformed at the time of press fitting, resulting in the deformation or displacement of the axle openings of the flange members. Specifically, the flange member includes a press-fitted portion that is press-fitted in the end-opening portion of the sleeve member, an axle opening portion including the axle opening, and a linking portion that extends in a direction parallel to a circular cross section of the sleeve member upon press fitting. The linking portion links the axle opening portion with the press-fitted portion. When the press-fitted portion is press-fitted in the end-opening portion of the sleeve member, an outer peripheral surface of the press-fitted portion that contacts an inner peripheral surface of the end-opening portion is subjected to stress from the inner peripheral surface of the sleeve member. When the stress is transmitted from the press-fitted portion via the linking portion to the axle opening portion, the axle opening in the axle opening portion is deformed or displaced. When the axle opening is deformed or displaced, the position of the axle opening of the flange member with respect to the central axis of the sleeve member is displaced, thereby decreasing the runout accuracy. It has been difficult to manufacture the photosensitive drum having a high runout accuracy in a stable manner. Japanese Laid-open Utility Model Publication 01-136959 (“Patent Document 1”) discusses a flange member having an elastic structure. However, the stress absorbing capacity of this elastic structure is not very high, so that the axle opening may be readily deformed or displaced, resulting in low runout accuracy. Further, the structure of Patent Document 1 includes areas where the sleeve member and the flange member are not in close contact with each other, resulting in the problem of idle rotation or detachment. Japanese Laid-open Patent Publication No. 08-123251 (“Patent Document 2”) or Japanese Laid-open Patent Publication No. 10-288917 (“Patent Document 3”) discloses a flange structure in which the linking portion includes straight ribs and opening portions between the ribs. By providing the opening portions, when the outer peripheral surface of the press-fitted portion is subjected to stress from the inner peripheral surface of the sleeve member, the stress can be absorbed by deformation of the linking portion around the opening portions. In this way, the deformation or displacement of the axle opening due to the stress applied to the axle opening portion can be prevented. However, in the disclosures of Patent Documents 2 and 3, the ribs linking the press-fitted portion and the axle-opening portion are straight-shaped. Thus, when the stress is applied to the straight ribs in a direction along the length of the ribs, the stress is not absorbed by the opening portions upon press fitting but instead directly transmitted to the axle opening portion. As a result, the axle opening is deformed or displaced, resulting in a decrease in the runout accuracy. The above problems may arise not just in the flange members attached to the sleeve member for the photosensitive drums, but also in the case of any flange member that is press-fitted in an end-opening portion of a cylindrical member.

The invention relates to equipment for stripping a multi-core cable, wherein a transport unit for transport of the cable in the axial direction of the cable, a knife for desheathing the cable and a further knife for stripping the untwisted cable cores are provided. A stripping device for multi-core cables has become known from the disclosure of WO99/52188. Cable cores are mechanically untwisted by a stripping movement and oriented parallel to one another before the cable cores are stripped by means of multiple knives. The stripping movement and the parallel orientation are achieved by means of spring-loaded, mutually opposed jaws, wherein the jaws act as resilient slide members. The cable cores execute a movement relative to the slide members whereby the untwisted cable cores are separated and oriented to be parallel before the stripping. A disadvantage of the known equipment resides in the fact that, due to the stripping movement, forces act in the cable""s axial direction on the insulation of the cable cores which slightly stretch the insulation. After the stripping, the insulation can compress again, resulting in overly-large, material-dependent stripped lengths. The present invention avoids the disadvantages of known equipment and presents a construction by means of which the cable cores of a cable can be untwisted and oriented in problem-free manner. The advantages achieved by the invention are essentially to be seen in the fact that the resilient insulation is not stretched during untwisting of the cable cores. The stripped length of the cable cores does not change after the untwisting. The stripped length of the cable cores as predetermined by the stripping is maintained. Moreover, shorter desheathed lengths can be realised, because the insulation is not stretched. The invention includes a transport unit for axial transport of the cable, a knife for desheathing the cable, means for untwisting the cores and orienting the cores parallel to each other, and a knife for stripping the cores. The cores are untwisted and oriented parallel without the application of an axial force to their installation. The untwisting and orientation may be performed by a separator which may include rollers, engage the cores and act transversely to the axial direction of the cable.

The clinical course of lung metastases from breast cancer. The clinical course of 50 breast cancer patients whose first metastases were found in the lungs was investigated. 18 months after the start of primary treatment 50% of the patients had developed pulmonary metastases (range: 0-81 months). In 23% of patients a solitary, and in 68% more than one, lung metastases were detected. After a median time of 4 months, in 56% of patients the disease had spread to further organs with bone (25%) and liver (17%) being the most frequent sites. First line management of lung metastases employed surgery, endocrine treatment, chemotherapy or a combination of these modalities. In 24% of patients a complete response was achieved, and in 11% a partial response, with an overall response rate of 35%. Median survival from detection of lung metastases was 13 months (range 4-123+). Patients with only a solitary lung metastasis survived for a median of 11.5 months as compared to 10.5 months for patients with more than one pulmonary metastases. Patients with a disease-free interval of more than 18 months survived significantly longer than patients with a disease-free survival of 18 months or less.

DESCRIPTION: (Provided by the Applicant) Over 5 million people who suffer preventable morbidity and mortality are admitted annually in the U.S.; consuming about 30 percent of acute care costs ($180 billion annually). Previous studies suggest that nearly every ICU patient suffers a potentially life threatening adverse event. To reduce this, we must learn what is broken and fix it. We hypothesize that we can improve patient safety; improve safety culture; and reduce ICU mortality, blood stream infections, aspiration pneumonia and ICU length of stay. To accomplish this, we will partner with the Michigan Hospital Association, whose has over 130 Michigan hospitals, to implement a safety program and other interventions in a cohort of hospitals. The specific aims of this project are to implement and evaluate the: (1) impact of the Comprehensive Unit-based Safety Program that includes the ICU Safety Reporting System; (2) effect of an intervention to improve communication and staffing in ICUs; (3) effect of an intervention to reduce/eliminate catheter related blood stream infections in ICU s; (4) effect of an intervention to improve the care of ventilated IC patients; and (5) effect of an intervention to reduce ICU mortality. To implement these aims, we will develop interventions for MHA who will then interact with Michigan hospitals to implement these interventions. Hospitals must commit a team--including a senior executive (vice-president or above), an ICU director or ICU physician, ICU nurse or nurse manager, and a department administrator--to collecting required data and attending 2 meetings and 2 conference calls/year. All teams will work on specific aim 1 and then choose one of the other specific aims every 6 months. By the end of the two year project, each team will have implemented all 5 specific aims and able to coach each other. Successful completion of this project will lead to significant improvements in patient safety across a state.

Reproductive physician-scientists for the twenty-first century. As we enter a new century, departments of obstetrics and gynecology in American medical schools face a number of challenges. A primary concern is the relative dearth of physician-scientists to explore basic mechanisms of cell function and relate these to the diseases of women. The question arises, what can we do to revitalize the spirit of investigation in many of our academic departments? This report reviews three programs designed to develop academic investigators: the Reproductive Scientist Development Program, the American Gynecological and Obstetrical Society/American Association of Obstetricians and Gynecologists Foundation Fellowship Program, and the Women's Reproductive Health Research Career Development Centers. On the basis of a decade of experience with the first two of these programs, the prospects for the third are promising. Clearly, the opportunities for obstetrician-gynecologist basic and clinical scientists are considerable. The question remains: Will leaders in the specialty work together to meet the challenge?

In numerous medical applications it becomes necessary to connect one section of tubing to another. In such situations it is important that the connection be secure so that it will not pull apart and that there be no leakage of fluid at the site of the connection. This is especially critical in applications where the tubing sections are implanted in the human body. U.S. Pat. No. 5,405,339, which is incorporated herein by reference, teaches connector for connecting sections of medical tubing and a method for using the connector. The connector has an enlarged middle portion between first and second end portions. The end portions have a smaller diameter than the enlarged middle portion and are adapted to be inserted into the ends of the medical tubing sections. The connector can be grasped at the enlarged middle portion, thus simplifying the process of inserting the end portions into the tubing sections. Additionally, the opposing edges of the enlarged middle portion act as tubing stop surfaces that provide a positive indication that the connector is properly aligned. While the invention described in U.S. Pat. No. 5,405,339 has solved numerous difficulties in the manufacture and use of the prior art medical devices, there is still certain areas for further improvement. For example, FIG. 3 of U.S. Pat. No. 5,405,339 teaches an addition of a circumferential suture groove in the surface of the enlarged middle portion that can only be used as a place at which the catheter may be anchored by suturing it to surrounding tissue if the connector is used without a strain relief. Col. 5, lines 37–43. It would be desirable to provide a connector that provides a place at which the catheter may be anchored by suturing it to surrounding tissue, while at the same time providing a strain relief. It would also be desirable to provide a connector that provides stronger connections with greater useful life, and which is simple to use.

Development of immunity to lungworm in vaccinated calves treated with an ivermectin sustained release bolus or an oxfendazole pulse release bolus at turnout. The ivermectin sustained release bolus (IVSRB), when used at turnout as recommended, will provide season-long control of parasitic bronchitis, thus obviating the need for use of a lungworm vaccine. However, some concerns have been expressed that calves treated with an IVSRB will receive so little exposure to Dictyocaulus viviparus that it will compromise their immunity in subsequent grazing seasons, which would be of particular importance in dairy herds. Although there is evidence that IVSRB-treated calves can develop immunity to D. viviparus when exposed to pasture infection, it was considered worthwhile to evaluate the compatibility of the IVSRB and lungworm vaccination to allow veterinary surgeons the option of using these products concurrently when they have particular concerns about the long term immune status of replacement dairy heifers. Thirty-two dairy replacement heifers were vaccinated with two doses of lungworm vaccine and, at turnout, half the calves received an IVSRB and the remainder an oxfendazole pulse release bolus (OPRB). At the end of the grazing season four replicate bolus treated pairs and four parasite-naive calves were challenged with 1000 D. viviparus infective larvae. At slaughter there was a 95% and 93% reduction in D. viviparus burdens in the IVSRB and OPRB treated calves respectively, compared with the unvaccinated, untreated controls. These results indicate that where it is considered necessary to use lungworm vaccination in addition to an IVSRB or an OPRB, the compatibility of these products with lungworm vaccine will allow development of a protective level of immunity to D. viviparus.

Comparison of three methods for measuring locations of long range base pairing in single-stranded DNA by electron microscopy. A comparison was made of three procedures used for measuring the locations of long range base pairing in single-stranded DNA. All three procedures gave equivalent results for the location of a transposon, Tn903, and for a loop created by pairing between the nut and operator segments on an EcoRI restriction fragment of lambda DNA. DNA molecules prepared by a T4 gene 32 protein procedure had the best contrast. The highest frequency of measurable loops resulted from a procedure which utilized ammonium acetate/formamide spreading conditions. This procedure also appeared to be the simplest and most satisfactory procedure. Only one procedure revealed the fact that the nutR and oR regions are separated by several hundred bases, but this procedure, which involves crosslinking with trioxsalen, gave generally unsatisfactory DNA morphology. None of the procedures revealed the existence of a short "bulge" loop of single-stranded DNA located between nutL and oL and a longer "bulge" loop located between nutR and oR.

Internet telephony, also known as Voice over IP (Internet Protocol), or VoIP, is the routing of voice conversations over the Internet or any other IP network. In VoIP, voice data flows over a general-purpose packet-switched network, instead of the conventional dedicated, circuit switched voice transmission lines used with conventional telephony, also known as plain old telephone service (POTS). Telephones require electrical power to operate. In POTS, a combined voice signal and power signal is transmitted over twisted pair cable between a telephone and a line card at a public telephone exchange. Unlike POTS, where the voice signal and power signal are combined and require only two wires, Ethernet uses four pairs. In a 10Base-T (10 Mbps) or 100Base-T (100 Mbps) Ethernet system one pair is used for the transmit signal, a second pair carries the receive signal and there are two unused or spare pairs. To provide a similar ease of use for VoIP phones as for conventional phones, configurations have arisen that provide power to a VoIP phone from a power source over an Ethernet connection. Power over Ethernet (PoE), or IEEE standard reference 802.3af, allows the electrical power necessary for the operation of a powered device to be carried by data cables rather than by separate power cords. This minimizes the number of wires that must be used in order to install the network and eliminates the need for AC outlets and AC/DC adapters for each powered device, resulting in lower cost, easier maintenance and greater installation flexibility. There are two main types of PoE devices: endspan and midspan. An endspan device is generally a network switch that transmits the data signal and provides power. It resides at the end of a link. Endspan devices can provide power in either of two ways: “phantom” feed devices provide power over the active or signal (transmit and receive) wire or line pairs; or power can be sourced on the unused or spare pairs. A midspan device fits in between a switch and a powered device, and can be mounted adjacent to the Ethernet switch in an equipment rack or located near the peripheral end device such as an IP Phone. A midspan device, or power adapter, typically supplies power on the unused wire pairs and simply passes the data signal through without modification—it does not include any transmit or receive functionality. A midspan power adapter is typically a stand-alone device, making it suitable for use with a network switch that does not support PoE. Furthermore, since midspans are less expensive than endspans, midspans are a cost-effective way of adding PoE on a port by port basis to an existing network. As such, IP phones are conventionally powered by a midspan power adapter where adding endspan PoE devices is cost prohibitive. FIG. 1 illustrates a system 100 in which a conventional IP phone 102 is coupled to a known midspan power adapter 104, which is in turn coupled to a network switch 106. The midspan power adapter 104 includes, or is otherwise connected to or in electrical communication with, a power source 108. The power source 108 in FIG. 1 is connected between device connector wire pairs 4,5 and 7,8. The power source 108 is typically 48 volts DC, and can comprise one or more batteries, or an uninterruptible power supply (UPS). More typically, and as shown in FIG. 1, the power source comprises an AC adapter which can plug into a typical wall outlet. The AC adapter can include a power supply 110, a transformer 112, and a wall plug 114. Connection between the IP phone 102, the midspan power adapter 104, and the network switch 106 is conventionally enabled by cabling 116, such as Category 5, or CAT5, cabling. Different categories of cabling can be used for different equipment, such as 10/100/1000 Mbps Ethernet, also known respectively as 10/100/1000 Base-T, with 1000 Mbps Ethernet also being known as Gigabit Ethernet. Midspan power adapters typically feed the signal wires directly through a first set of wires, identified as wires 1 to 3 and 6 in FIG. 1. Power is injected on the phone (or powered device) side from the power source 108 via spare pairs, shown as pairs 4,5 and 7,8 in FIG. 1. On the switch side, the spare wires are usually unterminated. Cutting the spare pairs to insert power, and not properly terminating the pairs significantly changes the common mode impedance between each pair within the cable. This discontinuity alters the balance and symmetry of the cable, causing an increase in radiated emissions when a midspan power adapter is used with an IP phone. Thus the powered device may exceed emission limits when in operation. The design intent for powered Ethernet devices, such as IP phones, is to have minimal electromagnetic emissions. Discontinuities such as those encountered in midspan PoE adapters can significantly elevate emission levels. It is possible to provide power to an end device without breaking or cutting the spare pairs inside the midspan power adapter. However, there is no way of knowing what the spare pairs are connected to at the network switch 106. For example, if a resistive load is attached at the network switch 106, placing power on the spare pair could destroy the load. For this reason, a break in the spare pairs is generally provided in a midspan power adapter. Unfortunately, this break also causes an increase in the amount of radiated energy. Several methods exist for containing unwanted emissions. One approach is to add a common mode filter clamp on an Ethernet cable to be used with a powered device. This involves customers placing chokes on cables which often does not occur, and makes cable management difficult since the chokes can be bulky. Alternatively, a choke could be moulded onto the cable, but this can be costly and standard replacement cables cannot be used. Another approach is to add common mode chokes within the powered device either as discrete parts or embedded into the Ethernet connectors. A further approach is to use shielded cable throughout any links containing a midspan power adapter. Shielded cable, however, is more expensive and not as commonly used as the Unshielded Twisted Pair Category 5 Ethernet cable specified for use with IP Phones today. Rewiring a building tends to be cost prohibitive. In general, these approaches merely add extra filtering and cost to each IP phone, rather than fixing the source of the problem. The problem lies in the midspan power adapter and the radiated energy it causes. It is, therefore, desirable to provide a midspan power adapter that can power an IP device without adding significant radiated energy to the system.

The universal serial bus (USB) provides a low cost solution for attaching peripheral devices to a host, such as a host computer or host server, so that the peripheral devices and the host can communicate with each other. Devices that are attached to a USB bus are automatically detected, and software automatically configures the devices for immediate use typically without user intervention. The USB devices/peripherals may include devices such as printers, scanners, keyboards, a mouse, digital cameras, digital video cameras, data acquisition devices, modems, speakers, telephones or video phones, storage devices such as ZIP drives, or other peripherals or devices. A USB bus can be extended with a hub which permits additions peripherals, or other hubs, to be coupled to a USB bus. The USB specification entitled “Universal Serial Bus Revision 2.0 Specification” available at www.usb.org, the disclosure of which is hereby incorporated by reference in its entirety, dictates various requirements and protocols for devices connected with a USB bus. For example, issues relating to power management are included in the USB specification. In particular, the USB specifications define that devices may be low power devices drawing up to 100 mA of power from the USB connection or high power devices drawing up to 500 mA of power from the USB connection. Recently, several extensions were added to the USB specification including an “on the go” (OTG) feature. The OTG feature permits two USB devices coupled to one another to communicate without the presence of a host computer. Another extension was added to delineate protocol for dedicated battery chargers, use of USB host as battery chargers, and a “No Dead Battery” provision to allow USB devices to temporarily draw power during connection to each other. Several different configurations have been produced to integrate the aforementioned USB protocol extensions. However, the configurations either introduce additional external hardware, which increases board area, or do not operate independently off of a battery or other external power supply.

Relationship between the descending branch of the inferior gluteal artery and the posterior femoral cutaneous nerve applicable to flap surgery. Flap surgery in the distal part of the gluteal region has to deal with a lack of detailed descriptions of the inferior gluteal artery and the posterior femoral cutaneous nerve. The existing papers are mainly clinical studies, based on low numbers of observations. Our study includes 118 cadaveric gluteal regions. The descending branch was present in 91% and gave rise to a cutaneous branch. When the descending branch was absent, this cutaneous branch came from the medial or lateral femoral circumflex artery or as a perforator of the deep artery of the thigh. The posterior femoral cutaneous nerve was found in a common sheath of connective tissue with the descending branch of the inferior gluteal artery in 72% of cases. Nerve loops around the vessel are present in 29%. Our results show that a cutaneous or fasciocutaneous flap, either local or free, in this region can be reliably lifted on a cutaneous branch of the descending branch of the inferior gluteal artery without loss of sensitivity. However, the close relationship of the artery and nerve limits the arc of rotation in the case of a local flap.

1. Field of the Invention The present invention relates generally to a scanning system driving device used in an image forming apparatus, having a scanning system for illuminating and scanning a document, such as a copying machine or an image scanner, and more particularly, to an improvement in transmission control of a driving force of the scanning system driving device. As a scanning system provided for a copying machine or the like, there are two types of scanning systems: a scanning system in which an optical system is moved relative to a still document, and a scanning system in which a document platen is moved relative to a still optical system. In this specification, the term "scanning system" is used as a general term for the above described two types of scanning systems. Consequently, a scanning system driving device includes both a device for moving and controlling an optical system and a device for moving and controlling a document platen. 2. Description of the Prior Art An image forming apparatus such as a copying machine includes a scanning system for optically scanning a document by driving an optical system or a document platen. For example, in a copying machine comprising a scanning system in which an optical system is driven, a moving body holding a light source and a reflecting mirror is displaced at uniform speed relative to a document. Consequently, the surface of the document is illuminated and scanned. In the process, a photoreceptor is exposed by light reflected from the document, and an electrostatic latent image is formed on the surface of the photoreceptor. This electrostatic latent image is developed into a toner image, and the toner image is transferred and fixed to copy paper, to achieve copying. In such an image forming apparatus such as a copying machine, there are strong demands toward improvements in the image quality, along with miniaturization and higher speed. Therefore, improvements have been made for shortening the rise time elapsed before the scanning speed of the document by the scanning system reaches a predetermined speed, as well as preventing the nonuniformity of speed from occurring during the scanning of the document. The electrostatic latent image formed on the surface of the photoreceptor is formed by the light reflected from the document illuminated and scanned. In order to increase the copying speed, therefore, it is essential that the scanning system be moved at high speed. Furthermore, in order to accurately reproduce a document image, it is necessary to keep the scanning speed constant. On the other hand, if the copying machine is miniaturized, the moving distance of the scanning system from the home position to the position where illumination and scanning are started is short. Therefore, it is necessary to rapidly increase the moving speed of the scanning system. If the moving speed of the scanning system is thus rapidly increased so-called overshoot is produced. That is, the speed of the scanning system once exceeds the rated speed immediately before the speed of the scanning system reaches the rated speed. This overshoot degrades the copy image corresponding to the region in the vicinity of the position where illumination and scanning are started. Consequently, care must be taken to exclude the effect of the overshoot. A prior art technique in which the moving speed of a scanning system is rapidly increased and a copy image is not affected by overshoot is shown in FIG. 11. A driving force on the scanning system is supplied from a main motor, provided in the copying machine, through an electromagnetic clutch. FIG. 11(a) shows the change with time of the voltage applied to the electromagnetic clutch, and FIG. 11(b) shows the change with time of the moving speed of the scanning system. In this prior art technique, in order to rapidly increase the moving speed of the scanning system, the voltage applied to the electromagnetic clutch is instantaneously increased to a predetermined rated voltage at the time of starting the scanning system, as shown in FIG. 11(a). This predetermined rated voltage is a voltage applied to the electromagnetic clutch when the scanning system is driven at rated speed so as to illuminate and scan a document. In FIG. 11, an idle period is a period elapsed from the time when the rotation of the main motor is started until the electromagnetic clutch is connected, an approach period is a period elapsed from the time when the scanning system is in the home position until it reaches the position where illumination and scanning are started, and an image forming period is a period during which the document is illuminateded and scanned. In this prior art technique the electromagnetic clutch is instantaneously connected, so that the driving force from the main motor is impulsively transmitted to the scanning system. Immediately after the scanning system rises, therefore, the moving speed of the scanning system fluctuates, as shown in FIG. 11(b). If the moving speed vibrates, excellent image formation is not carried out. Consequently, a period during which the moving speed vibrates is taken as an approach period, and a period after the moving speed is stabilized is taken as an image forming period. In this prior art technique, however, it is necessary to ensure a sufficient approach period to stabilize the moving speed of the scanning system. Therefore, the distance from the home position to the position where illumination and scanning are started of the scanning system, that is, an approach distance, is increased. Therefore, there occurs a problem that the copying machine is prevented from being miniaturized. This problem is solved by another prior art technique shown in FIG. 12. In this prior art technique a applied to an electromagnetic clutch is gradually increased, as shown in FIG. 12(a), Therefore, a driving force from a main motor is gently transmitted to a scanning system. As a result, the moving speed of the scanning system is smoothly increased and stabilized at rated speed in a short time, as shown in FIG. 12(b). Consequently, no long approach distance is required, thereby making it possible to miniaturize the copying machine, unlike the prior art technique shown in FIG. 11. In this prior art technique however, a dedicated electric circuit of complicated construction is required to gradually increase the voltage applied to the electromagnetic clutch. Therefore, there occurs a new problem in that the cost is increased. Still another prior art technique by which this problem is solved is disclosed in Japanese Patent Laid-Open Gazette No. 148138/1986. This gazette discloses the technique for applying a pulse voltage to an electromagnetic clutch in the early stages of scanning and repeatedly connecting and/or disconnecting the clutch to achieve a substantially half clutched state. In this prior art technique, however, the pulse period, the pulse content and the like of the pulse voltage are not sufficiently considered. That is, the natural vibration of an optical system is promoted by repeatedly connecting and/or disconnecting the clutch, so that the image quality is liable to be degraded.

Enhancement of immobility induced by repeated phencyclidine injection: association with c-Fos protein in the mouse brain. Immunohistochemistry of c-Fos protein was performed to study changes in neuronal activity in discrete brain areas of mice repeatedly treated with phencyclidine (PCP) showing enhancement of immobility in the forced swimming test, this behavioral change being considered as avolition, which is one of negative symptoms of schizophrenia. Repeated treatment with PCP significantly prolonged immobility time in the forced swimming test, compared with saline treatment. The c-Fos protein expression of mice showing PCP-induced enhancement of immobility was increased in certain brain regions, such as the retrosplenial cortex, pyriform cortices, pontine nuclei, cingulate, frontal cortex and thalamus, compared with that of PCP-treated, non-swimming and saline-treated, swimming groups. These results suggest that increased c-Fos protein is involved in the expression of PCP-induced enhancement of immobility, and c-Fos expression plays a role in negative symptoms-like behavioral changes.

The range of atoms which can be cooled by lasers is limited to those which have a closed two level structure. Several schemes have been proposed which aim to extend this range by using coherent control of the particle momenta, but none have yet been demonstrated. We hope to implement these and other coherent manipulation schemes, and we begin with a system which is well understood and over which we can exert precise control. This thesis covers the design and construction of an experiment to demonstrate coherent manipulation of cold rubidium atoms collected in a magneto-optical trap. The lower hyperfine levels of these cold atoms very closely mimic the ideal two-level atom, and we use carefully crafted laser pulses to prepare, manipulate, and read their quantum state. The hyperfine levels are coupled using two fields whose frequency difference is equal to the hyperfine splitting. The way in which these Raman coupled levels can be used to emulate a two-level atom is explored, and the experimental apparatus used to create and control the driving fields is described in detail. The amplitude, frequency and phase of these fields is programmable, and complex manipulation schemes can be implemented merely by programming a computer. We have observed Raman transitions in the cold rubidium atoms, and the experimental methods used to detect these features amidst large experimental noise are discussed. Although we have not yet seen Rabi oscillations, we are confident that we can now have sufficient control to begin to implement simple interferometric sequences. However, there remain significant challenges if we are to coherently manipulate the momentum, and the prospects for such manipulation are discussed.

Hemoglobin enhances the production of tissue factor by endothelial cells in response to bacterial endotoxin. Human endothelial cells respond to bacterial endotoxin (lipopolysaccharide [LPS]) with changes that transform the endothelium into a surface with prominent procoagulant properties. Production of tissue factor (TF) in response to LPS is a major alteration that favors coagulation. Biologic activities of LPS have previously been shown to be enhanced by the presence of hemoglobin. Therefore, the ability of human hemoglobin (Hb) to modulate TF production by cultured human umbilical vein endothelial cells (HUVEC) was investigated. Cell-free Hb (10 mg/mL), either purified native (HbAo) or chemically cross-linked (alpha alpha Hb), was incubated with LPS (0.1 microgram/mL), and the mixtures then were added to HUVEC in culture. TF activity was quantified with a clotting assay and TF protein was measured with an enzyme-linked immunosorbent assay. Hb preparations greatly enhanced the production of TF activity (11- to 25-fold greater than TF produced by HUVEC alone) compared with minimal TF activity generated by LPS alone (only twofold greater than HUVEC alone). The enhancement of LPS-induced TF activity was Hb concentration-dependent over a range of 1 to 100 mg/mL. Cross-linked alpha alpha Hb also greatly enhanced the production of TF protein compared with TF protein generated by LPS alone (12-fold greater v 3.5-fold greater than HUVEC alone, respectively). The enhancement of LPS-induced TF protein was Hb concentration-dependent over a range of 0.1 to 2 mg/mL. Enhancement of TF activity by Hb required new protein synthesis. These results show that human Hb can augment the ability of LPS to induce endothelial cell TF and suggest that hemolysis associated with disseminated intravascular coagulation during sepsis may further stimulate coagulation. In addition, these results suggest a potential mechanism for generalized thrombosis in animals that has been associated with the infusion of cell-free Hb for resuscitation.

The present invention relates to methods of detecting carcinomas by measuring the level of a glycero compound, such as glycerol-3-phosphate, in a plasma, serum, or urine specimen from a patient. The method is particularly useful as a screening test for ovarian and breast carcinomas. Carcinomas such as ovarian carcinoma, lung carcinoma, colon carcinoma, and breast carcinoma are among the most frequent causes of cancer death in the United States and Europe. Despite decades of cancer research, mortality rates among persons who contract cancer remain high. This dismal outcome is due, at least in part, to an inability to detect the carcinoma at an early stage of tumor development. When a carcinoma is detected at an early stage, survivability increases dramatically. For example, when ovarian carcinoma is diagnosed at an early stage, the cure rate approaches 90%. In contrast, the 5 year outlook for women with advanced disease remains poor with no more than a 15% survival rate. Thus, early diagnosis is one of the most effective means of improving the prognosis for carcinomas. Frequently, however, detection of carcinomas depends upon the detection and inspection of a tumor mass which has reached sufficient size to be detected by physical examination. For instance, transvaginal sonography is the most sensitive of the currently available techniques used for detecting ovarian tumors. However, transvaginal sonography is non-specific, i.e. it will detect benign as well as malignant tumors. Accordingly, detection of an ovarian tumor by transvaginal sonography must be followed by a second diagnostic procedure which is able to distinguish benign tumors from malignant tumors. Moreover, transvaginal sonography is very expensive and, therefore, not useful as a screening procedure for large numbers of patients. Typically, benign ovarian tumors are distinguished from malignant ovarian tumors by surgical procedures such as biopsy of the mass or aspiration of the mass and cytological examination of the cells that are surgically removed from the patient. However, these techniques are highly invasive, expensive, and in the case of aspiration can lead to release of cancerous cells into the peritoneum. As can be seen from this example for ovarian cancer, several factors prevent the early detection and treatment of carcinomas. First, the carcinoma may be too small to be felt or seen on an x-ray or sonogram. Second, once the carcinoma is located, it may be mischaracterized as benign by the histologist examining a biopsy from the tumor. Third, the intensely invasive nature of these procedures prevents their use by patients and prohibits their use as regular screening techniques. The detection of molecular markers of carcinogenesis and tumor growth can solve many of the problems which the physical examination of tumors have encountered. Samples taken from the patient for screening by molecular techniques are typically blood or urine, and thus require minimally invasive techniques. Thus, they can be used on a regular basis to screen for carcinomas. In addition, because molecular markers often appear before the tumor is of a detectable size, it is possible to detect carcinomas at very early stages in the progression of the disease. However, special processing of the samples is often required, and the molecular marker used is often of limited specificity and diagnostic value. For instance, the antigenic determinant CA 125, which is a high molecular weight mucin-like glycoprotein, is the current serum biomarker of choice for screening for ovarian carcinomas. However, CA 125 testing suffers from two main limitations. First of all, it is not very sensitive. For example, elevated serum CA 125 levels, i.e. levels above the cut-off point of 35 U/ml, are present in fewer than 50% of the patients with Stage I ovarian carcinoma. Taylor, K. J. W. and Schwartz, P. E., xe2x80x9cScreening for Early Ovarian Cancer,xe2x80x9d Radiology, 192:1-10, 1994. In addition, CA 125 testing is not very specific. For example, approximately 25% of patients with benign gynecological diseases also have elevated serum levels of CA 125. Moreover, liver disease such as cirrhosis, even without ascites, elevates serum CA 125 levels above 35 U/ml. Taylor, K. J. W. and Schwartz, P. E., xe2x80x9cScreening for Early Ovarian Cancer,xe2x80x9d Radiology, 192:1-10, 1994. Additionally, the level of lysophosphatidic acid (LPA) in the blood of patients has been used as an indicator of ovarian cancer and other gynecological carcinomas. For example, see the method disclosed in Xu, et al., U.S. Pat. Nos. 5,824,555, and 5,994,141. In this method, the plasma sample is first prepared from the blood of the patient. The sample may then be enriched by extracting lipids from the plasma sample with organic solvents in order to separate the LPA from other lipid components of blood. An LPA level of 0.1 xcexcM or greater is then assayed in the sample in order to diagnose the patient as having an ovarian carcinoma. Although LPA concentration is conventionally determined by gas chromatography, LPA may also be measured by enzymatically converting LPA to glycerol-3-phosphate, and then determining the level of glycerol-3-phosphate produced from LPA by an enzymatic cycling assay, see WO 00/23612. Although levels of LPA and other lysophospholipids in the blood have been shown in the blood of patients with carcinomas, see WO 98/43093, no similar instance has been shown for the endogenous levels of glycero compounds such as glycerol-3-phosphate. The present invention provides a new, simple method for detecting the presence of carcinomas in a patient. The method comprises detecting the presence of an endogenous glycero compound such as glycerol-3-phospate (G3P) or a glycero compound derivative thereof (GPX) in a plasma, serum, or urine sample of the patient at levels which correlate with the presence of a carcinoma. An embodiment of the method comprises: collecting a serum, plasma, or urine specimen from the patient, assaying for the presence of G3P, GPX, or a combination of glycero compounds in the specimen, and correlating the presence of the glycero compound at levels indicative of a carcinoma with the presence of the carcinoma in the patient. Glycero compounds suitable for assaying in the present invention include glycerol-3-phosphate (G3P), glycerophosphoinositol (GPI), glycerophosphocholine (GPC), glycerophosphoserine (GPS), glycerophosphoglycerol (GPG), and glycerophosphoethanolamine (GPE). In preferred embodiments of the invention, the xe2x80x9cglycero compoundxe2x80x9d assayed is a combination of these glycero compounds. A preferred embodiment of the method assays for the presence of the glycero compounds by an enzymatic cycling reaction utilizing glycerol-3-phosphate dehydrogenase and glycero-3-phosphate oxidase. If non-G3P glycero compounds are assayed in the invention, it is preferred that the enzymatic cycling reaction step be proceeded by an enzymatic step which cleaves non-G3P glycero compounds in the specimen to produce G3P. The method of the present invention can be used to detect a broad range of carcinomas at an early stage, including breast carcinoma, ovarian carcinoma, cervical carcinoma, uterine carcinoma, endometrial carcinoma, peritoneal carcinoma, and fallopian tube carcinoma. Because the method is sufficiently sensitive to detect ovarian carcinoma in patients with early stage ovarian carcinoma and marginally invasive, the method is especially useful for screening patients for ovarian carcinomas. For the same reasons, the method is especially useful for screening patients for breast carcinomas, as current screening techniques (such as mammograms) are relatively expensive and uncomfortable for the patient.

1. Field of the Invention The present invention relates to an advertising device for commercial purposes. 2. Description of the Related Art An advertising device comprises a billboard panel for sticking advertising bills thereon. The bills are stuck on the panel by means of an adhesive agent like a paste for securing them to the panel with certainty. By coating the paste on the panel or the bill, the bill surface is secured with respect to the panel surface. However, the operation of coating the paste on the panel or the bill and sticking the bill on the panel and the operation of removing the bill from the panel are troublesome and time consuming as well as costly. On the other hand, it is proposed to secure the bill to the panel by means of a pin or a nail instead of adhesive agent so as to easily stick the bill to the panel and remove it therefrom. However, when the bill is stuck to the panel by means of pin or nail, openings are easily formed between the bill and the panel so that the bill is apt to be torn by the draft passing through the openings.