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This invention relates generally to pressure regulating devices for use with irrigation equipment and, more particularly, to a device for regulating the downstream pressure of a remotely controlled water supply valve. As is well known in the art, it is highly desirable for an irrigation sprinkler, or other irrigation equipment such as a trickle irrigation emitter, to be supplied with water at a constant predetermined pressure. In this way, the irrigation device can be operated at a pressure which provides optimum performance and efficiency and the user of the device can accurately plan and control the amount of irrigation water applied. One way in which this has been accomplished is by providing a pressure regulator adjacent the inlet of each sprinkler. Naturally, this arrangement accomplishes the desired result, but the expense of providing and maintaining a separate pressure regulator for each sprinkler may not be justified by the advantages gained. Another method for regulating the pressure supplied to irrigation devices is to interpose a pressure regulator in the supply line to the devices immediately downstream of the remotely controlled valve. Although this method also functions satisfactorily, the pressure regulator must be relatively large in order to conduct the large volume of water supplied to several irrigation devices, and again, the expense of providing and maintaining a larger number of such pressure regulators can be prohibitive. Accordingly, there has existed a need for a convenient and effective device for regulating the pressure supplied to an irrigation device, such as a conventional sprinkler or a trickle irrigation emitter, which is relatively inexpensive to manufacture and can be adapted for use with conventional remotely controlled supply valves. As will become apparent from the following, the present invention satisfies that need.
New transmission schemes for extending a transmission rate are required according to an increase in an amount of communication due to the widespread use of mobile communication terminals such as smart phones and tablets. As one of such schemes, a Long Term Evolution (LTE) time division duplex (TDD) scheme is adopted in addition to a conventional LTE frequency division duplex (FDD) scheme. The FDD scheme is a duplex scheme in which frequency bands for use in an uplink (hereinafter referred to as “UL”) and a downlink (hereinafter referred to as “DL”) are provided separately. The FDD scheme is a scheme in which a transmission rate is increased by independently performing UL and DL transmissions. However, because frequency resources are finite, it is difficult to newly allocate a broadband for the FDD scheme. Thus, an LTE TDD scheme of dividing UL and DL with respect to time by using the same frequency band is beginning to be adopted. Because the TDD scheme requires half a band as compared with the FDD scheme, it is possible to effectively utilize frequency resources therewith. On the other hand, as one method of transmitting radio waves transmitted from a wireless device such as a mobile phone base station to a plurality of dead zones which radio waves do not reach, a distributed antenna system (DAS) for drawing a slave station for a base station in each dead zone in a wired manner is provided. The DAS can not only eliminate the dead zone but also can reduce an installation space for a base station. Thus, DASs are being actively used in zones which radio waves do not reach such as the inside of buildings, underground malls, and tunnels. Here, if the LTE TDD scheme is applied to the DAS, it is necessary to perform switching of transmission/reception using UL and DL. If there is a deviation between a switching timing of the transmission/reception of the DAS and a switching timing of the LTE TDD scheme, UL and DL interfere with each other and communication quality deteriorates. Due to this mutual interference, the transmission/reception of a control signal between a base station and a user terminal is obstructed, so that communication of the user terminal is disabled. Thus, in the LTE TDD scheme, a guard time is provided between UL and DL in order to prevent mutual interference between UL and DL. Mutual interference between UL and DL can be prevented by performing switching of the transmission/reception of the DAS during this guard time. In order to perform switching of the transmission/reception of a DAS during the guard time, it is necessary to detect the beginning of an UL signal or a DL signal. If the beginning of a signal can be accurately detected, it is possible to perform transmission without affecting the communication quality even if the signal has a short guard time. Conventionally, the beginning of the UL signal or the DL signal is detected based on a switching timing between UL and DL estimated on the basis of configuration information in the LTE TDD scheme. However because it is necessary to decode a received radio signal to acquire the configuration information in the LTE TDD scheme, an apparatus constituting the DAS becomes complicated. Also, as another detection method, the beginning of the UL signal is detected by estimating a radio signal of a user terminal connected to a macro base station that can be an interference source on the basis of an output of a detector. However, because the output of the detector generally has a variation of about several microseconds, it is difficult to detect the beginning of the signal with high accuracy. As described above, it has conventionally been difficult to detect the beginning of the UL signal or the DL signal with a simple configuration and high accuracy.
Cancer is a major public health problem. It accounts for approximately one quarter of all deaths in the United States, and is the leading cause of death among men and women under 85 years of age. The lifetime probability of developing cancer is 46% for men and 38% for women. Many anti-cancer therapies are plagued by side effects including nausea, emesis, hair loss, fever, and risk of infection. Chemotherapy and radiotherapy both lead to high rates of oral and gastrointestinal (GI) mucositis in treated patients, and these effects can be the dose-limiting toxicities of some treatment modalities. Tumor cells acquire a high level of adaptive heat shock response. The heat shock response is an adaptive mechanism used by all living cellular organisms to survive under the conditions of so-called proteotoxic stress—the condition resulting in accumulation of misfolded proteins, which tend to aggregate leading to cell death due to global protein denaturing triggered by such aggregation. Cells can activate this protective mechanism by inducing synthesis of additional protein chaperones, known as heat shock proteins (HSP). Tumor cell viability may be dependent on heat shock response because they have higher rate of protein misfolding. However, the efficacy of thermotherapy techniques for cancer are limited by the induction of adaptive heat shock response, which can greatly diminish tumor cell sensitivity to treatment and limit the use of thermotherapy and other heat shock modulating treatments. Accordingly, there is a need for improved methods of inducing cell death.
Embedded academic writing support for nursing students with English as a second language. This paper reports a study which evaluated a brief, embedded academic support workshop as a strategy for improving academic writing skills in first-year nursing students with low-to-medium English language proficiency. Nursing students who speak English as a second language have lower academic success compared with their native English-speaking counterparts. The development of academic writing skills is known to be most effective when embedded into discipline-specific curricula. Using a randomized controlled design, in 2008 106 students pre-enrolled in an introductory bioscience subject were randomized to receive either the intervention, a 4-day embedded academic learning support workshop facilitated by two bioscience (content) nursing academics and a writing and editing professional, or to act as the control group. The primary focus of the workshop was to support students to work through a mock assignment by providing progressive feedback and written suggestions on how to improve their answers. Of the 59 students randomized to the intervention, only 28 attended the workshop. Bioscience assignment results were analysed for those who attended (attendees), those randomized to the intervention but who did not attend (non-attendees), and the control group. Using anova, the results indicated that attendees achieved statistically significantly higher mean scores (70.8, sd: 6.1) compared to both control group (58.4, sd: 3.4, P = 0.002) and non-attendees (48.5, sd: 5.5, P = 0.001). A brief, intensive, embedded academic support workshop was effective in improving the academic writing ability of nursing students with low-to-medium English language proficiency, although reaching all students who are likely to benefit from this intervention remains a challenge.
Investigational agents to enhance the efficacy of chemotherapy or radiation in pancreatic cancer. Pancreatic cancer (PC) continues to be a fatal malignancy. With standard treatments having modest impact, alternative courses of actions are being investigated such as enhancing the efficacy of standard treatment through sensitization of PC cells to chemotherapy or radiation. This review emphasizes investigational agents that increase the responses to chemotherapy or radiation in PC models. Our group has extensively investigated on Curcumin (Cur), analogs (EF31, UBS109, and L49H37), nanoparticles and a small molecule Tolfenamic acid (TA) for enhancing therapeutic efficacy in both in vitro and in vivo assays. Cur has a low level of toxicity and promising anti-cancer activity, however, its clinical development has been limited by low bioavailability. Cur analogs and nanoparticles were synthesized to improve Cur's efficacy and bioavailability. These compounds were found to be effective in enhancing the therapeutic effects of chemotherapy in pre-clinical models. Small molecules such as NSAIDs have also been tested for the anti-cancer activity and induction of response of chemotherapy and radiation. Interest in TA, a NSAID, has recently increased due to promising preclinical data demonstrating its anti-cancer properties with minimum toxicity. TA also synergistically increased the response of XRT in PC cells and in an orthotropic mouse model. With strong preclinical evidence, research aimed at developing less toxic therapies for PC using Cur analogues or TA is ready for translation into clinical testing.
Photocatalytic degradation of gaseous perchloroethylene: products and pathway. Batch photocatalytic degradation of 1000-ppm gaseous perchloroethylene (PCE) was conducted with UV irradiation such that nearly 100% was decomposed within 10 min. The main intermediate and final product were identified as trichloroacetylchloride (TCAC) and hydrogen chloride (HCl), respectively, and minor ones as dichloroacetic acid (DCAC), monochloroacetic acid (MCAC), carbon tetrachloride, chloroform, and phosgene. More than 90% of Cl- equivalent, i.e., the sum of the chlorine number in PCE, intermediates, and HCl, was compensated for during the time of PCE degradation; a result indicating that no other major chlorinated intermediates are present during the time of PCE degradation. In a similar experiment, 500 ppm of gaseous TCAC degraded into HCl within 3 h without producing DCAC or MCAC, where like PCE, more than 90% of Cl- equivalent, i.e., the sum of the chlorine number in TCAC and HCl, was compensated for during time of TCAC degradation. Accordingly, gaseous PCE is concluded to predominantly follow a degradation pathway of PCE --> TCAC --> HCl.
The present invention concerns filters, in particular air filters. More particularly, the present invention concerns the characterization of filter cartridge seal impermeability, and more precisely impermeability to air. Air filters are commonly used in industrial devices to separate gases from the particles they contain. The air filter may be used at the exit point of a device, to purify gases prior to release into the atmosphere; or at the entry point of a device to purify the air or gas used inside the device, for example at the entry point of a gas turbine compressor. By design, air filters are built to separate particles from gas, retaining them in a manner comparable to a sieve. The filter's interstitial spaces block the passage of particles while still enabling gas or air to flow. However, the particles retained in the filter place limits on efficient filter volume; and cleaning or replacement of the filter becomes necessary following a certain amount of usage. Filters are thus built in the form of cartridges. The cartridges are equipped with sealing means comprising attachment means and one or several gasket seals, which enable easy and fast replacement of the filter when it is obstructed or congested. However, in view of enabling proper function of the filter, it is also necessary to ensure that the filter cartridge and its sealing means are tight or impermeable to air or gas, to make sure that the circulating air or gas is effectively crossing the filter, and not taking a parallel path along which no filtration occurs.
LC-MS/MS-ESI method for simultaneous quantitation of metformin and repaglinidie in rat plasma and its application to pharmacokinetic study in rats. A highly sensitive and specific LC-MS/MS-ESI method has been developed for simultaneous quantification of metformin (MFN) and repaglinide (RGN) in rat plasma (50 μL) using phenacetin as an internal standard (IS). Simple protein precipitation was used to extract MFN and RGN from rat plasma. The chromatographic resolution of MFN, RGN and IS was achieved with a mobile phase consisting of 0.2% formic acid in water-acetonitrile (1:1, v/v) with a time program flow gradient on a Chromolith RP-18e column. The total chromatographic run time was 3.5 min and the elution of MFN, RGN and IS occurred at 1.64, 2.21 and 2.15 min, respectively. A linear response function was established for the range of concentrations 0.855-394 and 0.021-21.7 ng/mL for MFN and RGN, respectively. The intra- and inter-day precision values for MFN and RGN met the acceptance as per FDA guidelines. MFN and RGN were stable in battery of stability studies viz., bench-top, auto-sampler and freeze-thaw cycles. The developed assay was applied to a pharmacokinetic study in rats.
In developing and maintaining a proper golf swing it is customary for the golfer to use a golf club in a practice area to strike successive golf balls and thereby become more proficient in executing a proper golf swing. In those instances in which the golfer uses a golf club for hitting a ball from atop a tee it is not uncommon for the tee to be broken and/or dislodged from the ground by engagement of the golf club with the ball and its supporting tee during the execution of a swing. Having to replace a dislodged or broken tee is burdensome and takes away from the time otherwise available for practice. Some of the practice devices of the prior art have supports which simulate tees for supporting golf balls during a practice session. Some of such supports have objectionable characteristics such as being of such flimsy nature as to require frequent replacement. Others of such devices provide more resistance to golf club movement than is desirable, thereby precluding the player is experiencing the feel generated by the movement of a golf club into engagement with the ball during a proper stroke. The placement of a golfer's feet in relation to the position of the ball during the execution of a stroke has an effect on the flight of a struck ball. It is desirable, therefore, to make possible an arrangement by means of which a golfer may learn where to position his feet during successive strokes so as to enable him to practice golf shots which produce different results according to the placement of the feet. Apparatus constructed in accordance with the invention overcomes the objectionable characteristics referred to above and facilitates the golfer's making specific golf strokes.
Non obstructive high-risk plaque but not calcified by coronary CTA, and the G-score predict ischemia. The association of plaque morphology with ischemia in non-obstructive lesions has not been fully eludicated: Calcium density and high-risk plaque features have not been explored. to assess whether high-risk plaque or calcified, and global mixed including non-calcified plaque burden (G-score) by coronary CTA predict ischemia in non-obstructive lesions using non-invasive fractional flow reserve (FFRCT). In 106 patients with low-to-intermediate pre-test probability referred to coronary 128-slice dual source CTA, lesion-based and distal FFRCT were computated. The 4 high-risk-plaque criteria: Low-attenuation-plaque, Napkin Ring Sign, positive remodelling and spotty calcification were recorded. Plaque density (HU) and stenosis (MLA,MLD,%area,%diameter stenosis) were quantified. Plaque composition was classified as type 1-4:1 = calcified, 2 = mixed (calcified > non-calcified), 3 = mixed (non-calcified > calcified), 4 = non-calcified, and expressed by the G-score: Z = Sum of type 1-4 per segment. The total plaque segment involvement score (SIS) and the Coronary Calcium Score (Agatston) were calculated. 89 non-obstructive lesions were included. Both lesion-based and distal FFRCT were lower in high-risk-plaque as compared to calcified (0.85 vs 0.93, p < 0.001 and 0.79 vs 0.86, p = 0.002). The prevalence of lesion-based ischemia (FFRCT<0.8) was higher in high-risk-plaque as compared to calcified (25% vs. 2.5%, p = 0.007). Similarly, the rate of distal ischemia (40% vs 17.5%) was higher, respectively. Lower plaque density (HU) indicating higher lipid plaque component (p = 0.024) predicted lesion based FFRCT in low attenuation plaque. For all lesions (n = 89) including calcified (p = 0.003), the correlation enhanced. Positive remodelling and an increasing non-calcified plaque burden (G-score) in relation to calcified were associated with lower FFRCT distal (p = 0.042), but not the SIS and calcium score. High-risk-plaque but not calcified, an increasing lipid-necrotic-core component and non-calcified mixed plaque burden (G-score) predict ischemia in non-obstructive lesions (INOCA), while an increasing calcium compactness acts contrary.
COMPUTER TODAY A computer is an electric device that is used to perform repetitive calculations at very high speed. The computer acts as a data processing device and also stores large amounts of data. This data could be text, pictures, voice, numbers, photographs and other types of information that are used by humans in their day-to-day operations. Life cannot be imagined without computers. In fact, the new millennium is the era of computers and its associated techniques, commonly known as Information Technology (IT). Computers help the school children learn new techniques of study, graphic designs, games and other useful educational applications. They help the college students in preparing reports. They help the office executives in accounts, software development, sale invoicing and manufacturing. They help the libraries in the efficient management of their operations. They run the factories and equipment. They control the satellites and nuclear weapons. They help the young and the old through the Internet sites. They are, in fact, indispensable as every operation of human life is incomplete and inefficient without them. As school-going students, we must learn computers. Computers are available in various configurations. For learning computer operations a computer with 166 MHz speed (Known as the CUP speed), a HDD of 1.2 MB storage capacity... read more
The present invention relates to a novel key board switch unit with illumination suitable for use even in a dark place. Many modern electronic appliances, e.g. electronic pocketable calculators and the like, are provided with a key board switch unit for operating the instrument. There are growing occasions of operating such a key board switch unit in a relatively dark place such as in automobiles at night so that many of the key board switch units are provided with a means for illumination. The most simple method for illuminating a key board switch unit is the illumination of the board from above with a suitable lamp. Alternatively it is also conventionally practiced that the surface of the key top is coated with a phosphorescence or fluorescence material which emits visible light in a dark place to assist the recognition of the key board by the operator. Further, the pushing areas of the key top are made with a transparent or translucent material and illuminated with a suitable light source installed just below the pushing area of the key top. The first method of illumination from above is the simplest in principle and sufficient lighting is readily obtained. This method is, however, impracticable when a very thin design of the key board switch unit is desired. In addition, complete shielding of stray light is sometimes very difficult in such a top illumination bringing about troubles such as glaringness when the key board switch unit is used in the room of an automobile or in a photographic dark room. The second method of the use of a phosphorescent material is defective in the insufficient intensity of light emitted from the phosphorescent material so that it is not always suitable as an illuminating means of a key board switch unit. The third method of the illumination from below the pushing areas of the key top also has a problem when a compact design of the unit is desired and uniform illumination of all of the pushing areas of the key top is obtained only with a considerable number of the light sources so that the method is not applicable when the electronic appliance having the key board switch unit is very thin as pocketable electronic calculators. Thus, it has been an eager demand to develop a key board swtich unit with illumination free from the above described problems in the prior art and many attempts have been made therefor but without success.
"(Heavy breathing)" "And the fourth angel poured out his vial upon the sun and power was given unto him to scorch men with fire." "And the fifth angel poured out his vial upon the seat of the beast and his kingdom was full of darkness..." "(Breathing unevenly) No..." "The enemy is closer than you think." "(Heavy breathing) No!" "No!" " No!" "No!" "No!" "No!" "No!" " (Bird shrieks)" "(Whimpering)" "The King's doctor at once!" "(Heavy breathing)" "(Thunder)" "(Intro music)" "♪ I'm the King of my own land ♪" "♪ Facing tempests of dust ♪" "♪ I'll fight until the end ♪" "♪ Creatures of my dreams rise up and dance with me ♪" "♪ Now and forever ♪" "♪ I'm your King ♪" "His humors are out of balance." "(Masson) (Sighing)" "(Masson) Majesty, drink this to help you sleep." "(Masson) It's a herbal cordial to allay your pain and procure your rest." "Laudanum, saffron and bruised cloves." "(Masson) I beg you, heed the counsel of your medical advisers." "(Louis breathes heavily)" "What do you say?" "Have you ever had a fever?" "I have, Your Majesty." "What measures did you take?" "To permit my body to cure itself, it was necessary to purge." "There's a herb, sagewort." "Known as sweet wormword." "Fetch your remedy, but quickly and with a calm air." " No one must know of his condition." " (Masson) Sire." "(Breathing)" "(Chuckling)" "(Chuckling)" "(Music)" "Love is in your future." "Twice as much as you might think." "(Scoffing) I'm off to water the garden." "(Grunting)" "I think that's a no." "(Grunting)" "(Yawning)" "(Coughs)" "(Yawning)" "You did not respond to my last message." "(Grunting) Well, to be perfectly honest it didn't seem pressing." "It was a busy week." "Fail me again and your next piss will be sitting down!" "You have my full attention." "(Heavy breathing)" "Read and follow... to the letter." "Don't breathe." "(Gasping)" "(signing)" "Were you raised in a cattle shed?" "Why are you here?" "Come at once." "The King's Circle." "Wake my wife." "Do it now." "(Tense music)" "(Panting and moaning)" "(Grunting)" "(Sighing, panting)" "What will you see just before the end?" "(Panting)" "The face of my enemy." "(signing)" "I've always dreamed the same dream." "I'm in a great avenue of evergreens, sitting in wet grass," "gazing through the pine cones at a canopy of sky." "Then if I were you." "I would stay indoors." "(Laughing)" "(Knocking)" "(Knocking)" " Speak." " (Man) The King's Circle." "(Knocking)" "(Tense music)" "(Tense music) (Footsteps)" "I must speak to you in private." "You're still drunk." "It can wait." "But the gravity of my need..." "All needs of yours weigh the same." "(Panting, stammering)" "A great tide is stirring." "It pertains to your future, your place at its center." "Go to bed." "Please." "Philippa..." "Philippe!" "In the King's book of names, you'll find a circle of trust, a list of those he believes in his heart are the most loyal, faithful and true." "(Colbert) Your names are on that list." "(Colbert) An unbroken circle of trust." "(Colbert) We all know here what is at stake." "How is my King?" "The fever is consuming him." "Protocol now demands we begin work on the issue of succession." "I will not hear it." "He is stronger than a malady, stronger than a hundred fevers." "Not this one clearly." "Your words are comforting." "My King values expediency over sympathy." "(Colbert) As we hope for the best, we must nevertheless plan for the worst." "(Rohan) Where did this distemper come from?" "Is it poison?" "(Fabien) I'll root out the cause." "I hope you have more success." "More?" "If a sick man gets to the King I don't call it victory." "The Dauphin is direct successor but would require a regent." "I would argue a young King requires a council of elders, with experience of government." "(Colbert) Protocol's clear." "If the King..." "Do not say it." "Dies, or if he is incapable of exercising his duties, a regent shall be appointed." "Who?" "That is the choice before us." "What is the news?" "We did not see the King at mass and you know people gossip." "Hunting accident, broke his leg." "It will take weeks." "Your Majesty, please!" "Rumors are flying around court." "The truth might stop them." "Why such secrecy?" "So that rumors do not start." " What would happen if..." " No "if"." "He will be well." "Yes, of course." "Jezebel!" "(Smashing of glass)" " Delilah!" " Stop it!" "You may have shaved my seven locks and sold me to the Philistines but I'm not yet on my knees." "If the King's hair hurts perhaps it was the wine." "Eat the beast's fur that bit you." "But who wants fluff for breakfast?" "(Jacket hits him)" "Was I out of turn?" "Come now!" "How is our King?" "(Sighing) Please speak." "Why all the secrecy?" "Speak!" "You must vow to me." " On my father's life." " He's dead." " My mother's?" " Forget it." "(Sighing) I cannot help my tongue." "Please!" "I see your distress and it pains me." "(Sighing) Allow me to share your burden." "Speak!" "My brother is very sick." "I always said you'd make a marvelous King!" "(inhales) Stop!" "So you're serious." "Goodness!" "He is gravely ill." "And if he were to die, it might be possible that I will be regent." "God in heaven!" "I had no idea." "Not a word to anyone." "This is a testing time but I know with you by my side," " I can overcome anything." " Hmm, yes, of course." "Now, I must have air." "Come with me, please." "I cannot." "I have to, um, think." "Very well." "He is in my prayers as are YOU." "(Clicking fingers)" "(Clicking fingers)" "What did you mean when you said "a great tide is stirring?"" "Did I say that?" "Hmm!" "I must have been drunk." "(Shouting in distance)" "(Coughing)" "(Gurgling) (Coughing, spluttering)" "(Horse galloping)" "Father?" "Father!" "(crying)" "Help me!" "Please, he's dying." " What happened?" " I don't know." "(Groaning)" "You must come." "The King." "He will perish." "As will your King." "Save your father or save France." "The choice is yours." " The King?" " He ordered my eyes to the door but he's not ordered them back." "Stay here." "(Whispering indistinctly)" "(Bontemps) Move." "Move!" "(Whispering indistinctly)" "Shut the doors." "Close all the shutters." "Door!" "Door!" "Ah, there you are." "I can't decide if this will be a courante a sarabande or a passacaille." "You must return to bed." "(Bontemps) Your doctor is here." "I've created a new dance, Bontemps, and I wish my court to perform it." "Very well, Sire." "Everyone must learn it now." "Bring me a pen and paper and a gardener." " A gardener?" " Yes, my gardener Jacques." "He lost his hand in Malines." "Bring him here." "I see this dance unfolding in a garden, an orangerie full of blossom." "I didn't see you at our recent ballet." "I dance as commanded by you." "Then do so now." "Dance for me now." "Follow me." "First, a balancé." "Twice going forward and then a pas de bourrée." "Then another balancé going backwards, then another pas de bourée." "(Humming)" "If these are your steps, Sire, then your dance is a passacaille." "You're a man of quality Bontemps." "But I do not trust you," "I do not trust you at all." " Sire..." " I do not know him!" "Your Majesty, please!" "Where is my gardener?" "I need him." "Bring me Jacques!" "Guards!" "Please, bring me Jacques!" "Guards, bring me Jacques!" "They mean to kill me!" "They mean to kill me!" "Bring me Jacques!" "Water for the King!" "(Whimpering)" "My gardener will know what to do... (Bontemps) Shh..." "Shh... (Heavy breathing)" "His fever grows stronger." "(Bontemps) Your Majesty, the gardener." "(Footsteps)" "Tell me a story about my father." "Your mother suckled him young before you, which makes you milk brothers, does it not?" "A story, then." "Many years ago, an emissary from Japan visited our shores." "(Jacques) He brought a gift from China for your father, an ancient text that he said that every general in the emperor's army had read." "(Breathing)" "The text was called the Art of War." "(Jacques) So the story went around the palace of this most vital maxim:" ""Appear weak when you are strong and strong when you are weak."" "(Coughing)" "Out." "(Coughing)" "Out!" "Out!" "(Coughing)" "(Praying in Latin)" "(signing)" "Yes, Madame de Clermont!" "Forgive me." "I'd always assumed your office was in the east wing." "It is." "As promised Monsieur Colbert, our proof of noble heritage." "Ah!" " Good." "I will review it in due course." " Good day." "(Retching)" "(Coughing)" "We can't put his life in a child's hands." "Hardly a child." "My brother should be in Paris." "I have readied my own carriage." " I'll take him." " He can't travel." " An hour at most." " (Marie) It may kill him." "It is this palace that is killing him." "(Grunting)" "(Breathing)" "I was just in the laundry, I found this in one of the pockets." "The same shapes as you have in your book." "Don't go anywhere." "A meeting is planned for today. ls my horse ready?" " Fed and watered this morning!" " You've done well." " There's no one here!" " (Fabien) Yes, I noticed that myself." "(signing)" "Cassel, we are risking our lives being here." "I had to conceal my horse half a mile away." "You're one to talk." "Why the urgency?" "You didn't write it?" "It appears we are not the only ones bound by our intent." "Which is what, exactly?" "Revolution." "This is a monumental risk." "What if these were intercepted or deciphered?" "They have been deciphered." "Then our location is known?" "(Beatrice) Once a codex is broken it offers opportunity." "I wrote a new note, made sure it was found." "It proposes a rendezvous today on the other side of Paris, so we are quite safe here." "Cousin?" "(Beatrice) A great moment is upon us:" "the King has a fever and his sickness grows." "(Beatrice) We must plan quickly now for our future." "We have powerful and wealthy friends, some already at court." "Others, abroad, are watching very closely, all of them standing, ready to help." "A support message from the Dutch Republic." "A new captain general is rising in power." "William of Orange will be stadtholder commander of armies, sea admiral." "And he vows here to support whoever moves against King Louis, not just with words, but with money, materials, influence and arms." "I've heard enough." "Thank you for the puppet show." "Chevalier de Lorraine!" "Do not confuse the woman you have known with the woman you see now." "A gathering in Paris awaits you." "Canvas your supporters there." "(Beatrice) We know there are many." "(Coughing)" "The fever has broken." "The court mustn't know about my condition." "But surely your brother must be informed." "Close all the doors." "Do it now." "The issue of regent remains." "We know your position, of course." "Will no one vouch for me?" "It is not you who lacks merit, Your Highness." "Our concerns lie instead on those who would be around you." "Ah!" "Why not just say his name?" "We need someone whose behaviour is more suited to a King, someone who is his own man." "I hope I make myself clear." "Perfectly." "Her Majesty and Monsieur Colbert would, to my mind, ensure a resilient transition." "(signing)" "(Tense music)" "Then it is settled." "What are you doing?" "(Chevalier) Rumors make me giddy." "I'm going to Paris for a few days to un-giddy myself." "(Clicks)" "You said I'd make a great King." "And you would." "This is not idle chat." "What is this?" " You made a vow to me!" " And I kept it." "Then be truthful in return." "Have you been under a rock?" "We are on the verge of change." "There are whispers growing louder every day." "People are tired of how it is." "They wish to see change, one that would not deny the monarchy but share in its burden." "You can see it in your brother now." "One man cannot rule the land." "He's drowning in it," " (Chevalier) and you can save him." " You tread a dangerous path." "The only danger is smelling smoke and not acknowledging a fire." " You side with the nobles?" " I side with you just as the soldiers do." "Would you side with me?" " You cannot know what you're asking." " I know what I'm asking." "Until death forces my hand," "I cannot answer." "Very well." "But know this:" "Our future has changed, no matter what happens now." "My trunk!" "Sire, we rejoice at your recovery." "(Louis) Send tailors I want clothes." "As for my court, this is the message I want to convey." "(Bontemps) I am saddened to report the King's health has not improved." "He awakened before breakfast and passed on instructions that government continue under his word." "How can he make decisions in such a condition?" "The King wishes France to be informed immediately of his condition so they might offer their prayers." "Has he said anything?" "He has..." "The court should learn a new dance." "A dance?" "It is one he has composed himself in his moments of peace... to raise our spirits" "in anticipation of his recovery." "Colbert, tell Monsieur Lully to create a melody." "(Sniffling) (Whimpering)" "Your sacrifice won't be forgotten." "(Louis) My deep sympathy for your loss." "I know now my replacement for your father." "What is his name?" "I know that he stands before me now." "Many will oppose you, who would rather I chose one of my physicians." "(Louis) Be deaf to their judgements." "Will you accept the job?" "(Louis) If the answer is yes there is no going back." "Your life as you know it will be changed forever." "I accept." "Then it is yours." "Medicine is a fine career." "(Louis) Get Mlle de la Vallière." "(Whispering indistinctly)" "Where's Chevalier?" "I haven't seen him today." "He rides to Paris." "A gathering of nobles." "Does he indeed?" "What are you doing?" "Did you not hear?" "The King has a dance and expects us to know it." " Why are you here?" " Getting Mme Rochefoucauld's letter." " This is her chamber?" " No, this is Mme de Clermont." "Mme de la Rochefoucauld is down the hallway." "Oh my goodness, I'm so sorry!" "Excuse me." "Wait!" "I hoped you might stay here, you might think of this as home." "I cannot." "Not even for your children?" "For their sakes and for mine," "I must show contrition for my life." "You may go." "Thank you," "Majesty." "Thank you with all my heart." "Arrangements will be made." "(Giggling)" "Mother, I have missed you." "Every time I look for you, I am rushed back to my lady." "Your duty to me is to do well with her." "Do not think of me at all." "I found a chambermaid in your room." " Chambermaid?" " Yes." "Looking for Mme Rochefoucauld's letter but ended up in your room." "I went to the chapel." "Cassel was in conversation with new nobles, Anjou, Poitier..." " Who else?" " Mme de Clermont." "(Sighing) Since the court knew of the King's condition, conversations between these individuals increased markedly." "Anjou and Poitiers... too you say, both to Cassel." "I asked the stables, Potters, Anjou are riding to Paris." "(Fabien) Not the only ones." "Chevalier de Lorraine also reached Paris this morning." " About Clermont..." " (Fabien) Later." "Where are you going?" "Christ Jesus, life eternal in the bosom of the Father... life of souls made of your own likeness," "protect my brother in his time of need." "My God!" "(Laughs)" "I was told you were dying!" "I was but then I recovered." " You didn't tell me?" " I told no one." "(Philippe) Why?" "So I might see upon who I can depend." " You did not include me." " I did not." " You do not trust your own brother?" " Not the company he keeps." "(Deep breath)" "Chevalier may seem blithe and glib, but he has a backbone." "I wish you saw what I do:" "He's a man of honor." "You are blind to his failings and dumb to his faults." "Do not say such things." "A conspiracy was uncovered, nobles plotting against me as I am ill in bed." "(Louis) Chevalier is a ring leader." "All of them will be arrested." "Impossible." " He's no conspirator." " Very true." "He's a traitor and will be treated as such." "(Sobbing)" "To Versailles!" "(Fabien) Good idea." "(Grunting)" "The Duc d'Orléans will have your head for this for sure." "(Chevalier) When your neck's on the block you know what he will say?" "(Fabien) No." "(Spluttering)" "In any case," "I hope you're fond of horses." "(Breathing unevenly)" "(Gasping, choking, grunting)" "(Panting)" "Burn in hell you Catholic cunt." "(Spitting)" "(Coughing)" "I found a little something to aid us." "(Fabien) Aid us with what?" "(Beatrice) Endurance." "A love potion." "When I look at you I need nothing else." "Oh, I'm the same." "But I think it might be fun." "Come." "(Moaning)" "(Retching)" "(signing)" "(Whispering indistinctly)" "(Classical music)" "(Courtiers exclaim)" "(Classical music)" "(Coughing)" "(Coughing)" "(Choral music)" "Thank you." "(Choral music)" " (Man) Ha!" "Ha!" " (Nobleman) (Screaming)" " (Nobleman) (Shouting indistinctly) - (Priest) (Praying in Latin)" "(Screaming)" "(Screaming)" "(Whimpering)" "(Music)" "(Music)"
Generally, an LSI test is performed by using automatic test equipment (ATE). Test data used in the ATE is generated by using the ATPG tool which can automatically generate a test pattern satisfying a remarkably high coverage (failure detection) in a short time. The test pattern generated by this ATPG tool (hereinafter, referred to as ATPG pattern) is used to verify system operation and timing, and is converted to a pattern to be interfaced to the ATE. FIG. 1 is a flowchart which shows an outline of a conventional timing verification method for LSI test data. As shown in FIG. 1, conventionally, test synthesis is first performed based on a first netlist 121 (chip data 1) according to a specification based on customer requests or the like (step S121). Layout processing such as a cell arrangement and intercell wiring are performed based on a resultant second netlist 122 (chip data 2) (step S122). The ATPG tool automatically generates an ATPG pattern based on a resultant third netlist 123 (chip data 3) (step S123). Data (test vector) 124 comprising the generated ATPG pattern is used to perform a timing verification with a gate simulation (step S124). This timing verification is started at the stage when verification of the system operation is almost completed. The verification of the system operation is omitted in FIG. 1. When a violation is found as the result of the simulation, the first to third netlists 121, 122 and 123, and data (test vector) 124 are appropriately corrected (step S125). When the result of the gate simulation is good, the test vector is released to a production division (step S126), data (test vector) 125 comprising the test vector without violation is converted to an ATE data format (step S127). Thus, data (test vector) 126 comprising the ATE test vector is acquired. So far, the timing-verified test data is acquired. The acquired test data is used for an ATE test (step S128). However, in recent years, a large scaling of an LSI has been advanced, and the data amount of the ATPG pattern has been remarkably increased. Therefore, there has been a problem that it takes an enormous time for the gate simulation. Further, when a timing failure is found with the simulation, the gate simulation is performed again after the failure is corrected, and therefore there has been a problem that it takes an enormous time to acquire verified test data. Further, there has been a problem that the data amount of the ATPG pattern is large and therefore a design environment such as a disk capacity to be used is pressed when the ATPG pattern is converted to the ATE pattern after the timing verification, or that it takes a very long time to handle the data. As a measure against the problem that the gate simulation time is long, it is considered that the timing verification is performed on only a part of the ATPG patterns to reduce the verification time. However, with this, the timing verification is not performed on all the ATPG patterns, thereby, a yield in a shipment test may be greatly reduced. When it is necessary to correct a critical portion (critical path) on the system operation as a result of the timing verification, a designer is burdened with finding the portion to be corrected from the ATPG patterns and manually performing a pattern correction. Generally, with respect to the system operation, a static timing analysis tool (hereinafter, referred to as STA) is used to perform the timing verification for a synchronous circuit portion, and the gate simulation is performed only for an asynchronous circuit portion. Further, with respect to function verification, a formal verification tool is used to reduce the number of steps in the entire verification. As described above, in the other verification than the timing verification of the ATPG pattern, the verification time is reduced. However, the STA is not used for the timing verification of the ATPG pattern. The reason is because, since a semiconductor designer does not know how to perform the timing verification of the test circuit automatically generated through test synthesis, a condition of the STA cannot be set. Further, the reason is because, since the result of performing the timing verification with the STA cannot be input into the ATPG tool and reflected, there is no assurance of a coincidence between the result of static timing analysis and the ATPG pattern. Further, when a test mode is erroneously set, a timing verification may be failed. Further, as another reason why the STA is not used for the timing verification of the ATPG pattern, a high-speed simulator dedicated to a scan pattern may be considered. This high-speed simulator performs a reduction of a simulation time by omitting the timing verification with respect to a shift operation of the scan pattern. However, due to enlargement of LSI in recent years, it takes a very long time for the simulation even when this high-speed simulator is used.
Frequency of parental report of problem behavior in children decreases with increasing maternal age at delivery. Child behavior problems were assessed in 1377 3-yr.-old twin pairs with the Child Behavior Check List from Achenbach (translated into Dutch language by Verhulst). The association between problem scores and maternal age at delivery of the twins was analyzed with statistical control for several potential confounding variables: birth weight of twins, maternal smoking during pregnancy, being breast or bottle fed and socioeconomic status. After controlling for all available confounding covariates, a significant linear effect for maternal age was left. Especially Externalizing behavior problems as well as the separate categories that constitute Externalizing, i.e., Aggressive, Oppositional, and Overactive, appeared to decrease continuously with increasing maternal age. This was true for both boys and girls as well as for first and secondborn twins. Evidence in support of a biological explanation of the association between maternal age and child behavior problems, is presented.
"Paris, April 1 958." "Dear family," "Memory is a strange muscle." "It moves on its own when we least expect it." "Today I went to the theatre where we are to perform." "While climbing the stairs I asked myself:" ""Have I locked the door?" "."" "as if I was home." "I remembered the stairs, the strange way that grandmother looked at them, as if it was a forbidden place." "Poor grandma." "Daughter!" "Lean on me, mother." "One, two..." "Celia!" "Don't be afraid." "Come on." "I'm not sure you remember, she was so afraid of falling backwards." "Nobody understood why, but we all walked behind her to help." "I remember, although I might be making it up, one Christmas Eve she drank a bit too much, and it was the only time she spoke about it." "If I ever fall down I'll never get up again." "But we're all here to help you." " lt's all the same." " Ernesto!" " Come on!" " Merry Christmas!" "The real discovery came later." "For one reason or another we never spoke about it again." "However the whole family continued their efforts to help grandmother." "Mom searched the whole city for shoes with nonskid soles and things of the kind." "Nora became a human cane." "Jorge and I could only play in the garden." "Dad had all the floor tiles changed and forbade carpets." "The house became a little strange but our life went on the same." "And it wasn't worse than others." "white lies" "What are you doing there:" "I couldn't sleep." "Why didn't you come:" "I had work to do." "It was my farewell, Jorge." "Well..." "Next time I'll go." " Here." " The last one." " Have it." " What do you want:" "Smoke." " Do you have everything ready:" " Yes, Auntie prepared everything." "Did you speak to Mom:" "I didn't want to worry her." "You're shameless." "What's better:" "To tell her the truth and sadden her:" "No..." "I don't know." "She'll find out anyway." "Why:" "Are you going to tell her, Jorge:" "No..." "Nora:" "No." "Then how will she find out:" "Eventually Mom always finds out about everything." "Put your hand like this." "What are you doing:" "Stop talking nonsense." "Here, put it out." " Listen to me." " Don't do noise." "Who is she:" "Patricia:" "Nice picture." " When did she give it to you:" " Just now." " Did you see her last night:" " Yes." " So:" " So..." "So what:" "In the end, yes." " Did you tell her:" " Yes." "And she thinks it's a great idea." "That I can be successful in Paris." "Like other musicians." "That's what they say." " Excuse me." " How will I do in Paris:" "Great!" "Where did you go dressed like that:" "To mass." " Where did he go:" " To mass, yes." " What about breakfast:" " What:" " You won't prepare it:" " Why me:" "Because you make it delicious, you're the best." "Ok, ok, I'm going." "Jorge..." "Why don't you check if the car's arrived:" "Slightly out of tune." "They'll send you back soon." " l hope." " Don't start, Mom." "How many students did the teacher invite:" "One." "But it's for so long, you're still so young." "Three months." "I'll be back before you know it." " Will you write to me:" " No, not even a single letter." "It's cold, stay in bed." "Pablo..." " Take care." " Take care." "And don't go around partying too much." "The car is here." "Are you ready:" "Yes." "Can you help me with this:" "It doesn't close." "Pablo!" "Excuse me." "Pablo, before you finish I want you to pack this." " What is it:" " Something for the trip." "Uncle!" "It's what your father would have wanted to do." "Yes, sure." "Go to Paris to play in a cabaret." " Dad would have loved it!" " Ok, let's go." "I'll tell Nora." "Don't listen to your brother." "He's so inexperienced." "Pablo." "I made something for the trip." "They serve meals on the ship." "You never know what they use to prepare them." "Take it!" "What is it:" " Sandwiches." " For the journey." "Can you take this for me:" " Pablo..." " What:" " l don't know how this works." " Simple." " There." " Okey." "It's late, come on, you'll miss your ship." "Mom." "What did I tell you:" "So we can all be in the photograph." "Let's go to the car." "Let's go." "Can you believe this woman:" "Give me your hand." "Here:" "Come on, it's my turn." "Come on." " What:" " Come on." "A picture:" "Mom should be in the middle." " Ahí." "Ahí, ma." " !" "Pará!" " Smile." " No, wait." "Come, Pablo." "I'll take it." "Get ready..." "One..." "Two..." "Three." " What's the matter:" " The engine won't start." " Maybe it ran out of fuel." " No, it's flooded." " What's the matter, Ernesto:" " lt's flooded!" " Can't you do something:" " What do you want me to do:" "Jorge..." "Take." "Take care of it." "Try again." " He'll miss the boat." " He won't!" " There it goes..." " That's it." "Bye!" "Be a good boy!" "Mom..." " Something else:" " What:" " Something else:" " No, it's fine." "Take a deep breath." "Again." "Again." "Jorge..." "Hello." "Hello." "It's been a while." "How are you:" " l'm fine, studying." " That's good!" "How are your Aunt and Uncle:" " Fine." " Say hello to them for me." "And Pablo:" "How is he:" "Fine." "He was to send us a postcard from a stop at a port, but it seems he didn't have the time..." " Didn't he write to you:" " No." "Well, you know how things are." "To arrive in a new place..." "Yes, it must be a mess." "Ok, I'm going..." "Regards." "I'll prescribe her some vitamins." " She's worried, that's all." " Yes, that's all..." "But it's all she talks about all day." "When did your nephew leave:" "About..." "Next Thursday it will be a month and a half." "Boys don't realize those things." "Yes, but he should send a letter to his mother, at least." "Maybe you could write it yourselves." "A short note, to calm her down." "Dear family:" "I'm sorry I couldn't write before, but rehearsals take very long." "Paris is a beautiful city." "I hope everyone is fine." "A big hug, and a kiss for mom, Pablo." "Very nice, isn't it:" " Rubbish." "He doesn't say anything." " What do you want him to say:" "Where's the stamp:" " l threw it away." " Why did you do that:" "It was on the envelope. I was so excited when I opened it that I tore it apart." "How are we going to answer to him:" "I copied the address on a piece of paper." "So, let's write to him now." "Fetch a pen and paper." "Dear, unruly Pablo, I was very glad." " We were very glad." " We were very glad... to receive your postcard... but we are also a little worried." "You didn't tell us about yourself." "We are glad everything is fine, but we want you to come back soon." "Look after yourself." "A big kiss." "Mom." "It's my fault." "I should have written something else." "We did it in a hurry." "What I'm worried about is Pablo." "What should we do:" "Keep waiting:" "I was thinking..." "Do you remember that employee we had:" "She married a Frenchman..." " Adela..." "Azucena..." " Almudena." "Almudena." "They moved to Paris." "Dad was so good to them in the past." "We can write her, and ask her to help us find Pablo." "Could she look for him:" "At least she can go to that place where he was to play." "Meanwhile she can send another letter to Pablo." "Another letter:" "I'll send it in an envelope and she only has to send it back." "We can give her some money." "What should we tell Mom now?" "." "We can tell her he is doing very well, playing with his teacher, that they asked him to play in more concerts." "Avery good offer, one he can't refuse." "In Paris... for a while." "For a little while, that's why he accepted it." "The offer is to play with an opera singer who is on a tour." " A famous singer." " An aristocratic woman..." " Called:" " Margarita!" " A French name..." " Veronique:" "Veronique..." " Mimi:" " Yes, Mimi Pinzon..." "Give me a break!" "Ludovica:" "And where is he:" "He's staying in a very elegant hotel in the center of Paris." "From the windows he can see the Eiffel Tower..." "With flags from every country..." "The hotel has a café" "The hotel has a café as big as our house... with glass chandeliers and brass doors." "Madam!" "Nora!" "It's Autumn here and the streets are covered with fallen leaves." "There are cafes everywhere, crowded until late at night." "Everyone is so elegant." "Last night the teacher and I had dinner with a very famous opera singer who came to congratulate us." "Her name is Marie Bergere." "She wants us to accompany her in some concerts that she is giving in cities all over France." "Can you imagine such a trip:" "It's an incredible opportunity for my career." "I hope you are as happy as I am." "I love you a lot." "A big hug, and a kiss for Mom." "Pablo." "Hey, good." "Our boy is doing well." "I'm so proud!" " Yes..." " Of course!" " What's the matter, Mom:" " l don't know." "I have something in my stomach." "Happiness!" "Yes." "But..." "I'm thinking of Patricia." "How will she react to the news:" " She'll be glad." " Sure." "We haven't heard from her for a while." "Why hasn't she come over anymore:" "Perhaps she doesn't want to bother us, with Pablo gone... I'm sure she doesn't know anything." "We should tell her." "Let's invite her for a meal." "We have to look after Patricia until Pablo returns." "It's the least we can do for him." " Come in!" " Thank you." "I brought this." "Mom loves chocolates." "You should give them to her." " Are you staying here:" "I'll bring her down." " Yes." "Patricia." " Hello." " Thank you for coming." "How could I not come:" " Have you had news:" " No, and you:" "We're trying to find out about him through a friend of the family in Paris." "She went to the place where he was going to play and it was shut down." "That's so strange." "That's Pablo... I don't know." "I'm scared." "Scared of what:" "Don't be silly." "I brought this." "You shouldn't have." "You're already one of the family." "Norita, put them on a plate, come on." "Excuse me." "See you later." "You're sad." "What's wrong:" "Nothing." "I was studying a lot." "Look me in the eyes." "You're lying!" "You don't need to feel that way." "Pablo loves you." "The thing is that he had an important offer for his future" "For the future of both of you." "Yes, I know... but it's difficult to think he is so far away." "I miss him too." "Between us, Pablo was always my favorite." "You're so lucky." "He is as well." "I believe that when he returns, he'll want to marry quickly." "Seriously, it's a premonition I have." "You may be right, but we have to wait." "We can't get our hopes up." " One can't live without hopes." " One can't live without hopes." " You'll be a beautiful bride." " Thank you." " But I think we should wait for a while." " No, on the contrary." "Let's begin preparing everything ourselves." "Dear Pablo, comma." "How could you start such an adventure without asking us:" "Are you forgetting about your family:" "You must finish your work and return." "You have commitments here as well." "What does your teacher say about all this?" "I don't want you to listen to everything he says." "You have to think about us." "Be careful." "France can be a dangerous country." "Return as soon as possible." "We need you, Mom." "Dear family, I know Mom is right, I was selfish." "But it was the only way to make a quick decision, lf you knew how difficult it was for me." "But, well, it's done." "Fortunately everything is working out very well." "Marie is a great singer, very thin, bony." "She always wears feathers on the stage;" "sometimes green, other times, black." "They always match her shoes." "She likes to wear eccentric hats, like Aunt Celia." "I told her we have a hat store, one of the most well-known shops in Argentina." "Well, I exaggerated a bit." "Last week we had our first concert." "It was in the Palace of Versailles." "You can't imagine how big it is." "There are almost 200 bathrooms." "I was so nervous that I got lost." "The concert was a success." "There were a lot of important guests, including ministers and film stars." "It's a pity I couldn't understand them." "I have to start learning French." "At least a few lessons..." "Excuse me." "You can't imagine how happy I am." "But don 't think this is easy for me, I miss you all, especially Patricia." "I sent several letters to her, but she hasn't replied yet." "You didn't write to him:" "I didn't receive any letters, yet." "Why don't you write to him now:" "Nora, fetch a sheet of paper for Patricia." "Not now." "I have to think of what to write." " But you'll write soon." " Yes." "It's a time of sacrifice for us all, I know that." "How lucky that Jorge is taking care of business, otherwise we'd be on the street." "I see French girls walking along the Seine and think of Nora." "Her commitment to her classes with those dull students who can't even learn the tables... I also think of auntie and uncle, always so supportive." "Uncle used to tell me:" ""You have to go far in life, very far." "So we can no longer hear you. " He was right finally." "Auntie would go mad in Champs Elysees." "There are trees shaped like animals." "A bear, a giant rabbit... ln Autumn the perfume of the trees fills the city." "I wish you were here with me." "Look what has arrived from Paris." "I love you all." "Pablo." "No." "Auntie, did the postman come:" "Yes." "He brought a package from Paris." "Your mother has it." " ls Patricia here:" " Yes, she's in the back." " Hi." " Look Jorge!" "A gift from Pablo." " What is it:" " l don't know..." " A kind of lamp." " lt's got a pattern inside." " What is it Nora:" " l don't know." "Does it revolve:" " l'll catch it." " No!" "Be careful!" "What a shame, your husband!" "And you:" "Help him go upstairs." "Don't let the children see him." " Let's cook it!" " lt's mine, leave it!" "Dad gave it to me." " Mom, where's Mr. Rabbit:" " lsn't he in the garden:" "We can't find him anywhere." " He must have gone into the forest." " The forest:" "Sure." "Rabbits live in the forest." "Dad brought him so that he could spend a holiday with us." "Perhaps he got tired of being so far away and returned..." " But, why:" " Perhaps he missed home." "Yes:" "Excuse me." "Mr. Millstein, come in." "I'm sorry to bother you in your own house, but I haven't seen you in the store lately." "I'm working a lot at home." "Yes, your uncle just told me that." "What can I do for you:" " l wanted to tell you the store is having some problems. -l know." "Then you'll agree that we should make some changes." " What kind of changes:" " First of all, to cut down expenses." "Perhaps we can do without one of the employees," "Or raise the prices." "Yes, that's reasonable." "Which of the options:" "I wouldn't dispense with one of the employees." "Perhaps reduce wages... I don't know." "You can figure this out better than me." "Do you know the wise saying:" ""The eye of the owner fattens the calf:" "My father used to say it." "Your father was a smart man." "If I were you, I would follow his advice." "I'll keep that in mind." "Now if you excuse me, I have to go back to work." "But we haven't decided what to do yet." "The lemons are so little." "They aren't ripe yet." " lf you want I can ripen some for you." " No, leave them." "Norita, cross lemons out." "Nora..." "Cross peppers out." "Do you have apples there:" "Apples, three kilos." "Stand up straight." "Do you know where they sat her:" "On the wicker chair." "She looks beautiful, it frames her." "What an idea to sit her on a wicker chair!" "That will blur the background." "Bring a green chair from the dining room." "That will emphasize her neck." "The neck..." "Nora!" "Don't use that chair." "Your mother says to bring one from the dining room." " Tell me, what's her hair like:" " Nora is tidying it." "She's leaving a fringe on her forehead." "That fringe, oh my god." "Clear her forehead, that tuft always covering her eye." "It's horrible, poor thing." "Nora!" "Don't leave that tuft covering her eye." " Like this:" " Yes." "I can't tell her it's horrible..." "What is she holding in her hands:" "Nothing, she has them crossed." "Make her hold a jasmine." "Nora!" "Your mother says that she should hold a jasmine!" "But the dress is pale." "In that case, a rose." "Nora!" "Not a jasmine;" "a rose would be better then." " Make up your minds!" " We're doing what we can!" "Celia!" "Don't shout at Norita." "They brought a rose for her." "Red..." "Red like blood." "A smile, please." "The garden is covered with flowers and you're still in France." "I hope that..." "No, we hope... that with these photos, you will remember your family." "Fa...mi..." "ly." "We love you madly." "Beautiful eyes..." "Raise your leg." "That's it." "Let's see." "Nice shoulder." "That's right." "Very well!" "Another one." "Your eyes glowing for uncle Ernesto, come on!" "The Naked Maja!" "What's the matter:" "Oil." " Did you ask Uncle:" " He's busy." "Can you use cooking oil:" "I'll check." "Hundreds, tens... and units." "How many there are:" " Uncle:" " Jorge?" "Can you open this for me?" "What are you doing:" " The key got stuck." " Which key, Uncle:" "The inventory:" "I'll keep it for you." "Dear family, I have great news to share with you." "Marie offered us to make a record with her." "Norita, the scissors!" "I'm sending you one, I hope it arrives in one piece." "It's on sale in all the shops in Paris." "I hope it didn't break." "There were very good critics in the papers." "I hope you like it." "Even better, we have many concerts to promote it already scheduled." "Not only in France, we'll tour Germany." "I have to prepare the luggage." "I love you all." "Take it, Norita." "Pablo." "Grands Opéras Françaises, Marie Berger." " This is wonderful!" " So important, isn't it:" " What are you doing, Mom:" " Let's listen to it!" "Leave it to us, you can listen to it from here." "No, I want to listen to it properly." "I'll come with you, wait." "Hold it for me." "And those musicians he brought:" "Does he think this is a cabaret:" "They're his friends, grandma." "Did you see the garden:" "No, you never see anything." "Only the naked dancers are missing!" "Mother, a party, once in a while..." "Once in a while your husband comes to visit." "Show a little respect, grandma." "My brother supplies for all our needs." "Respect:" "This is a family house, dear, and in my family..." "Please, stop fighting!" "The guests are arriving." "The guests, the guests." " Welcome." " Thank you." " Mr. Millstein." " Thank you for the invitation." " Please, step into the garden." " Yes, thank you." " The children room." " lt's really pretty." "Do you smoke:" "Thank you." "Norita!" "Come here." "Go upstairs to see where your father is." "Tell him I need to talk to him." "Mom, mom!" "This is the last time I hear you say something like that." "Mrs. Millstein felt bad and dad was helping her." "is that clear:" "Go and wash your face." "Doctor:" "Do you know an Opera Singer, called Marie Bergere:" "What:" "Marie Bergere:" " Yes." " The French singer:" "Yes." "Yes, I know her." "Let's see." "Take a deep breath." "Leave everything here." "I'll take care of that." "Excuse me." "Your uncle raised the prices again:" "Talk to him, I wouldn't charge you a thing." "Lito!" " Can you give me some water:" " Yes, sorry." "Why do you always treat me bad:" "Stop that." "My aunt is around." "Where:" "Under the table:" "No, she's with the doctor." "She took Mom's tests to him." " How is your Mom:" " Not very good." "She's worried about Pablo." "And your brother:" "He's doing very well." "He's touring with his band." " Really:" "What a surprise!" " Surprise:" "You know, the kind of friends he travelled with..." " l don't mean anything, but..." " Then don't say anything." "What's wrong:" "What have I done to you:" "You make me feel nervous, Lito." "Why so nervous:" "I have things to do." "You do too." "When are you going to have some time for me:" "When my brother comes back, we'll talk." "And what if he never does:" "Go away, Lito." " Ernesto, we are not making anything." " l know." "Today I went to the workshop and I talked to Caceres." "We're going to reduce the production." " Did you go to the Consulate:" " Yes, I did." " And:" " Nothing." "They only know he entered France." "What are we going to do:" "The only option is for somebody to go there." "And keep looking for him." " Yes, or claim him." " Claim him:" "At the mortuary, Celia." "The mortuary." "Such a pessimist." "We must be reasonable, Celia." "It's a possibility." " lt's Pablo's face, look." " And this..." "Maybe this is his room..." "It looks nice." "Such a good idea to send us these drawings." "He's more and more like Dad." "You haven't been to the club lately." "I don't go out much, actually." "You should go out, have fun..." "meet someone..." "That's what Pablo always says." "Pablo knows how to have fun." " l have to take care of Mom." " Sure." "Everyone has commitments." "Yes, of course." " Do you miss Pablo:" " Yes." "Like everyone else." "I'm sure he's fine." "And he'll come back soon." "I don't know what to think." "Well, we have to think about the wedding now." "Wedding:" "Patricia." "Hello, Jorge." "How are you:" "How did you do on your exam:" "Good." " That's good." " Yes." " Shall we go:" " Yes." " Patricia:" " Yes:" "Are you staying for dinner tonight:" " No, I can't." " Another day, then." "Another day, yes." "Let's go." "Mom is growing impatient." "Excuse me." "Did you see Patricia today:" "She's weaker every day." " Yes, poor thing." " Why poor:" "She should think more about Pablo." "Well, she's helping us a lot, isn't she:" "I think she's losing hope." "But I'm sure Pablo is fine." "Don't you think, Jorge:" "Sure!" "Besides, we can't think of him all day." "Pablo is a grown up and knows how to look after himself." "We have other things to take care of." " The store, for example." " Mom's health." "Despite what the doctor says, I see her improving every day." "Her spirit lifts every time she receives a present from Paris." "Yes, but we have to think about our finances." "How much is this comedy costing us:" "Mom's health is not a joke." "Of course." "But do you have any idea of how business is going:" " Not so well." " Like hell." "Ernesto!" "That's the way it is." "The numbers aren't good." "How to pay our debts:" "Production on the farm isn't good, either." "The foreman cannot handle it on his own." " Millstein says..." " Millstein will lead us to bankruptcy." "Since he took over things have worsened." "We must do something." "Like what:" "I don't know." "We must think about it." "I have an idea." "Dear family, I'm writing from the train that takes us on another tour." "From my window I can see beautiful houses under the snow." "It's a wonderful landscape, but I can't stop thinking about you." "One learns to value things when they are far away." "I miss my bed, Auntie's meals, Uncle's jokes... I was trying to find a place in town where they make pasta... I imagine Norita is still giving lessons and Jorge is taking care of the store." "It's hard to think that life continues the same, while I'm here in Paris... I saw a picture, and without a second thought I bought it." "It sometimes goes unnoticed but for me, here in Paris, the memory of the family is greater everyday." "I can't forget dad screaming:" ""Come back, you half-wit" when I broke the dinning room glass." "I think the glass was never replaced." "But I miss Patricia the most." "I think more of her everyday, I even write her name on steamy windows." "Please, convince her that this is the best for us." "Soon we'll finish the concerts, although the distance between cities is bigger." "Next week we are going to Berlin." "Then, Frankfurt, Viena, Milan, Rome... I hope we can soon be together." "Travels are more enjoyable when you share them with someone." "You can 't imagine how much I miss you all." "Pablo." "You look just like me the day I married." " lt should be... that way." " Yes." "It bothers me here." "Take it off and I... lt's the emotion." "Patricia." " What's the matter:" " l feel ridiculous." " Why:" " Jorge..." "Come in." "What's all this:" "Pablo's life in France." "I have something for you." "Pablo's favorite book." "He would want you to have it." "Pablo didn't read books." "Never mind, I accept it." "From you, not from Pablo." "Thank you." "Didn't you see Patricia:" " She left." " What did she do with the dress:" "She took it." "She liked it so much, she wanted to show it to her family." "That's so nice." "I'll tell your mom." "Attention!" " Very good!" " One more time, dad." "No, tomorrow." "Now Uncle and I have to leave." "What's that:" "Voilá!" "You should be the Finance Minister." "Don't play with the food." "Good morning." "Excuse me for a minute." "Keep eating, children." "Norita..." "Norita, are you ready:" "I'm almost done." "They're bringing her down." "Very good!" "You're going to kill me." "Be careful, Uncle." "Easy..." "Watch the door." "Be careful." "Be careful." " There you go." " A bit closer..." "Here Mom, I'll fetch the food." " Are you cold:" " l'm fine." "Just a bit out of breath." "Mom, we have a surprise for you." " Pablo will call tonight." " What do you mean:" "From Europe:" " ls that possible:" " lt's very expensive and difficult, but it's possible." " Excuse me." " That looks so good!" " Let's see." " What time is he going to call:" "I don't know, it depends on an international operator." "Who wants some salad:" "Mom, do you want salad:" "No, no, later." " Shall we make a toast:" " Yes, of course!" " Merry Christmas!" " Cheers." "Merry Christmas!" "Merry Christmas!" " To Pablito!" " To Pablo!" "Hello:" "Operator:" "Yes, I'll wait." "Pablo!" "Pablo!" "It's been a while!" "How are you:" "We're fine here." "We're all working hard." "What:" "Yes, I'll put her on the phone." "Hello:" "Hello:" "Pablo:" "Pablo, son!" "How are you:" "I don't understand!" "I know." "love you too so much!" "Hello:" "Hello!" "Pablo:" " Take me upstairs, please." " l'll take you." " Call the doctor, Ernesto." " Hello:" "Pablo:" "Pablo:" "Pablo:" "It was not a long distance call." "It was from Avellaneda." "What's the difference:" "You don't have to worry about money." "Who's talking about money:" "Nora and I have talked about this." " We decided that we're going to sell some furniture and clothes." "What:" "We both have clothes that we don't wear." "And Millstein always liked the chandelier in the living room." "Well, now he can buy it." "Don't you think we'd be better move to a smaller house:" "To take Mom out of this house:" "With what it means to her:" "To us:" " lt's the family house." " l think that..." "The house is the house." "We are not leaving it." "Period." "Doctor, how is she:" "The situation is complicated." " Be honest, please." " Four months." "Five." "I'm sorry." " This has gone up again." " The new government." "It's temporary until things settle down again." "That's what all governments say." "Dreams keep hope alive." "It's an antique, isn't it:" " Do you like it:" " Yes, very much." "It belonged to my father." "He won it in a brothel, playing cards." "If he won the bet, he'd keep the owner's woman," " a Polish woman with green eyes." " And if he lost:" "He'd have to give up his daughter." "What happened:" "The game was even, everyone in the brothel was there." "In the last hand dad was winning, but the police appeared." "There was a terrible stir." "Some ran away." "The polish girl was deported." "Her husband didn't even stop to protect her." "Dad grabbed the lamp and broke it on a policeman's head." "That's how he escaped." "I'll buy it." " l don't know..." "It's very valuable." " Tell me how much." "Mom, Mr. Millstein wants to say hello." "Excuse me." "Good evening." " How are you, Madam:" " Here I am." " How's the store doing:" " Much better." "It will be a great store, some day." " Like Gatt Chavez." " Something like that." "Why not:" "Your husband always had a good nose for business." "Yes." "Osvaldo was an intelligent man." "He also had a very good taste..." "in general." "What about your wife:" "Fine." "A beautiful woman." "You are a very lucky man." " Yes, that's true." " Well, I'll show you to the door." "Wait." "Celia, look in the wardrobe, on the upper shelf." " lt's late, Mom." " Just a second, Jorge." "The purple box." "Thank you." "Do you like it:" "It's very elegant." "Osvaldo loved it." "I kept it for a special occasion." " lt's unique." " Take it." " What:" " lt's a gift." "It will look better on your wife." " She would thank you, but..." " Try it on." "Precious..." "Take it." "Thank you so much." "No, thank you for all you do for us." "Well, I'd better leave now." "Good night." "I'll show you to the door." " What are you doing:" " Can't I give a gift:" "Don't you remember his wife left him:" "Besides, everybody knew he was cuckolded." "She took the shirt off his back." "Don't you remember:" "Terrible..." "I didn't remember." "How are the lessons:" "I'm not giving lessons anymore." "Too much housework." "Why don't you go out a bit:" "To distract yourself." "No." " Why not:" " Because. I can't." "They need me here." " Thank you." " Thank you." " Goodbye." " Goodbye." "Yes:" "It's Patricia." "Can I come in?" " Are you all right:" " Yes, why:" "I thought that..." "Mom's getting worse." "We had to bring oxygen." "I just wanted to see you." "And see if you are well." " l'm fine, yes." " Ok." "Wait." "No." "No." "Pablo." "What are we going to do when he returns:" "He won't return." "Why not:" "Pablo can't be alive." "Why can't he:" "Because we never got any news from him, Jorge." "Not even a postcard." "We don't know what happened to him." "He vanished." "Because if he were alive and he were doing this to us, he would be a bastard." " Pablo did send a letter." " What:" "Six months ago." "Nobody knew." "It arrived when I was by myself." "I didn't show it to anybody." " What:" " Pablo sent a letter." "He said he's all right, that things didn't turn out as expected, but he was looking for other opportunities." "When he has enough money for the ticket, he will return." " You're lying to me." " No, it's true." "I have the letter, I can show it to you." "I don't want to see it." "It's in the right drawer." "Look!" "Look!" "Don't you think Patricia is acting strange:" " Why strange:" " l don't know, she looks confused." "Perhaps she's overwhelmed with the wedding arrangements." "Yes, we shouldn't put pressure on her." "It's so much work... for all." "You shouldn't have fired the maid." "She was an unnecessary expense." "Maybe..." "But you all look so tired." " You don't look very good, Celia." " l'm better than ever." "Are you sure:" "It's the asthma." "It comes and goes." "My brother was the same." "He came and went." "Until one day he didn't come anymore." "And with Ernesto, how are you:" "Well." " Sure:" " Please... let's not start again." "If I say well, it means well." " See:" "You're out of breath again." " lt's the asthma, I told you." "You need fresh air." "Yes." "Sometimes I envy Pablo." "He must be well with his asthma." "You left it downstairs." "Aunt!" "We have to do some tests." "When:" "Tomorrow." "She'll have to stay at the hospital." " At the hospital:" " Yes, this is not a joke." "Will the tests be expensive:" "Don't worry." "I'll arrange that with your nephew." "What if I leave a note instead:" "You can't leave without saying goodbye." " Celia, Take care." " You too." "Say hello to the foreman, and to his wife." "I'll do it." "Dear Pablo:" "Change of the season has brought us some surprises." "Aunt Celia is not feeling very well, it's nothing too serious, don't worry." "The doctor said that all she needs is to spend some time in the countryside." "Uncle went with her, of course, two weeks ago." "They called from the village yesterday." "The farm seems to be improving." "This year the sheep had double breeding." "Patricia went on a trip with some classmates, too." "That's why she hasn't visited us for a couple of weeks." "Excuse me." "As you can see, you are not the only one who has been moving around." "I finished the letter." "Kisses to you." " Shall I read it:" " No, I'm tired." "Won't you sign it:" "Come on." "No, you sign it." "Hello." "Uncle!" "How's Aunt:" "Uh..." "What are you going to do:" "I understand." "The store:" "Fine as usual." "is it raining there:" "All the roads are blocked..." "No, if you're fine, stay as long as you want." "I'll tell them, don't worry." "Goodbye." "Kisses to Auntie." "We know it is hard, Uncle, but there's no other choice." "If Mom sees you she will ask about Auntie." "Yes, of course." "Besides, the people on the farm need a guide." "It'll be good for you to have other things to think about." "Yes, you're right." "This house holds too many memories." "I must insist, are you sure you won't take my offer:" "I believe my brother was clear." "The piano is not for sale." "Such a pity." " Here you are." " Thank you." "As soon as I have the money, I'll bring it." "Yes." "With this weather I'd prefer not to leave the house." "Thank you." " l'm leaving." " Aren't you staying for dinner:" "No." "All right." "See you." "Nora, I'm not coming back." "What:" "I've been thinking." "I can't go on. I'm sorry." " But Mom..." " Nora, she knows." " What:" " She realizes." "You're shameless." "I understand. I apologize." "I know that..." "You're making it up to justify yourself." "Did you forget about Pablo:" "Or did you find another man:" "I'm leaving." "Dear Mom, I hope that Aunt Celia gets better from her asthma." "The country will surely do her good, it did me good." "Living in the city is not healthy." "Last week here, a tiger escaped from the zoo." "Can you imagine?" "On the radio they asked people to stay in their houses." "People closed the doors and windows, fearing the tiger might enter." "Meanwhile, the tiger walked freely through the city, starving, scratching billboards and roaring." "In the end they caught it in a butcher shop." "They added poison to the meat." "The poor tiger crawled to the Seine and threw himself in." "From my window, I saw his body pass, floating on the river, swollen like a feather cushion, orange and black." "I received a letter from Patricia, telling me about her trip to the lakes in the South." "At least, there are no tigers there." "She says that the landscape was beautiful, but that the best thing about traveling is to return home." "I know we will meet soon, and I will give you a big hug." "I promise." "Pablo." "He writes better and better, doesn't he:" "Aren't you going to reply:" "No." "You write to him." "Tell him the news." " l'll leave it here." " Thank you, son." "Nora, what do you do with the stamps:" "What:" "What do you and Jorge do with the stamps:" "Jorge removes them with steam." "I stick them on a sheet and we cover them with tracing paper." "In the green album." "Don't you remember:" "Incredible..." "So much effort you put into this." "It's nothing, Mom, what are you saying:" "You're so good to me." "Uncle Ernesto called today." "He says that the fields won't be ready until next year." "With some luck." "Too bad." "Yes." "Lito came to the shop." "How is he:" "He's getting married." "Really:" "To whom:" "To the fisherman's daughter." "She's pregnant." "He doesn't want to be involved." "Her father is forcing him." "What a disaster, that boy..." "Did you hear that noise:" "No." "Jorge!" "ARGENTlN EAN TANGO musicians SUCCEED in paris" "Jorge!" "What is she doing here:" "Mom!" "Grab her legs, Nora." "Grab her legs!" "Sometimes the house seems too big." "Without the maid, and Aunt and Uncle on the farm, it seems to have too many rooms." "There are some places I don't enter anymore." "It will remain like this until we get used to it... or until you return." "You can 't imagine how much we wish to see you." "Patricia wants to organize a welcome party for you." "She asked me not to tell you, but I can't keep secrets from you." "If we can't trust our family, who can we trust?" "Nice earrings." "Do you like them:" "They are from Paris." "It seems this winter is colder than usual." "It hasn't stop snowing since New Year's Eve." "No." "Pablo told me there's so much snow that people can't get out of their houses." "He's lucky to live on the third floor." "Anyway, he always finds a way out of everything." "To go to work he skates on the Seine." " You must be lying..." " No, it's true!"
Eosinophilia in infants with food protein-induced enterocolitis syndrome in Japan. Many Japanese infants with food protein-induced enterocolitis syndrome (FPIES) show eosinophilia, which has been thought to be a characteristic of food protein-induced proctocolitis (FPIP). To elucidate the characteristics of eosinophilia in Japanese FPIES patients, 113 infants with non-IgE-mediated gastrointestinal food allergy due to cow's milk were enrolled and classified into FPIES (n = 94) and FPIP (n = 19). The percentage of peripheral blood eosinophils (Eo) was increased in most FPIES patients (median, 7.5%), which was comparable with that in FPIP patients (9.0%). Among FPIES patients, Eo was the highest in patients who had vomiting, bloody stool, and diarrhea simultaneously (12.9%) and lowest in patients with diarrhea alone (3.2%). Eo showed a significant positive correlation with the incidence of vomiting (Cramer's V = 0.31, p < 0.005) and bloody stool (Cramer's V = 0.34, p < 0.0005). A significant difference was found in Eo between early- (≤10 days, n = 56) and late-onset (>10 days, n = 38) FPIES (median, 9.8% vs. 5.4%; p < 0.005). IL-5 production by peripheral blood T cells stimulated with cow's milk protein in early-onset FPIES was significantly higher than that in late-onset FPIES (67.7 pg/mL vs. 12.5 pg/mL, p < 0.01), and showed a significant positive correlation with Eo (rs = 0.60, p < 0.01). This study demonstrated two types of eosinophilia in Japanese FPIES infants: conspicuous and mild eosinophilia in early- and late-onset FPIES patients, respectively. Conspicuous eosinophilia in early-onset FPIES is suggested to be caused by abnormally high IL-5 production.
The present disclosure relates generally to electronic displays. This section is intended to introduce the reader to various aspects of art that may be related to various aspects of the present disclosure, which are described and/or claimed below. This discussion is believed to be helpful in providing the reader with background information to facilitate a better understanding of the various aspects of the present disclosure. Accordingly, it should be understood that these statements are to be read in this light, and not as admissions of prior art. Liquid crystal displays (LCDs) are commonly used as screens or displays for a wide variety of electronic devices, including consumer electronics such as televisions, computers, and handheld devices (e.g., cellular telephones, audio and video players, gaming systems, and so forth). Such LCD devices typically provide a flat display in a relatively thin package that is suitable for use in a variety of electronic goods. In addition, such LCD devices typically use less power than comparable display technologies, making them suitable for use in battery powered devices or in other contexts where it is desirable to minimize power usage. Typically, LCD panels include an array of pixels for displaying images. Image data related to each pixel may be sent by a processor to the LCD panel through a driver integrated circuit (IC). The driver IC then processes the image data and transmits corresponding voltage signals to the individual pixels. Typically, the method by which the driver IC receives and processes the image data is well suited for receiving certain types of image data, such as video images for example, but not as well suited for receiving other types of image data, such as still images.
The proposed case-control study is designed to investigate dietary factors which may inhibit cancer of the colon and rectum. These include vitamin C, vitamin E, vitamin A (retinol), beta carotene, selenium and protease inhibitors. Dietary intake of fats and fibers will additionally be assessed. The cases will be about 350 newly diagnosed colorectal cancer patients at three hospitals. A series of 350 patients with non-neoplastic disease from these hospitals will serve as controls. An additional population-based control group will also be obtained. Questionnaire information will be obtained on non-dietary risk factors for colon cancer and on sociodemographic variables. Dietary intake will be assessed by an extensive dietary interview which will be directed toward recall of intake 2-3 years ago (preceding symptomatic disease). Nutrient intakes will be calculated from an extensive and up-to-date food composition database for most nutrients. In order to confirm the validity of dietary intake information and to ascertain more physiologically-relevant parameters, bilogical assays will be conducted for about 100 cases and 100 controls. Fecal samples will be obtained and assayed for levels of protease inhibitors. Hair, which provides a temporally-integrative measure of various trace metals, will be assayed for levels of selenium. Since several of the dietary factors in question have been shown to have joint potentiating or compensating effects, interactions among them will be investigated in addition to their separate inhibitory effects. Finding a reduction in risk associated with some or all of these dietary factors would point to dietary modification as a potential preventive measure for cancer of the colon and rectum.
Utility meters are used to determine the amount of a utility, such as electricity, gas or water, consumed at a given site. In particular, conventional residential electric meters are watt-hour meters which measure total energy consumed at the site and indicate the usage in standard kilowatt hours. Modern residential electric meters typically include solid-state electronics for monitoring, storing and displaying utility usage data over time. Total energy consumed, as well as other data, is digitally displayed. For billing and management purposes, a utility provider periodically sends a meter reader to the site to directly view and report the meter display. Data from the meter may also be downloaded from the meter into a handheld device. This is a time-consuming and costly process which has produced a growing demand for more cost-efficient methods of utility accounting. In response to the growing demand, automatic meter reading (AMR) technologies have been introduced, including radio-based, telephone line based, and power line based systems. Known radio-based apparatus and methods include meters equipped with low power radio frequency transmitters to transmit utility usage data from the meter to a central location such as a mobile van unit, or a central building. Optimal transmission efficiency requires an antenna equal in length to about 1/4 the wavelength of the transmission frequency. In particular, at the low frequencies typically used in remote meter assemblies, optimal transmission efficiency requires the use of antennas having lengths which are difficult to incorporate within a standard meter housing. Known radio meter assemblies address this problem by using a non-standard meter housing having towers or projections to accommodate an antenna projecting from the meter assembly. However, the manufacture of such specially designed, non-standard meter housings is costly. Further, the towers or projections can present obstacles for individuals passing or working near the meter assembly. Thus it would be desirable to provide a utility meter apparatus which includes a suitable antenna within a standard type meter housing. It would be further desirable to provide such apparatus which is simple and inexpensive to manufacture. In addition, it is generally desirable in providing meter apparatus to minimize the number and size of components and mounting hardware to minimize costs and labor. It would also therefore be desirable to provide utility meter apparatus which integrates a suitable antenna with other meter components, to minimize costs and labor.
Aircraft head lights, as they are employed in airplanes and helicopters, may comprise a plurality of lighting arrangements, each of said lighting arrangements comprising a reflector, in particular a reflector having a parabolic shape. With the parabolic reflectors, a strong collimation of light is achieved for providing a bright illumination in a desired direction. In order to use the available space efficiently, the lighting arrangements are arranged very closely to each other. A very close arrangement of the lighting arrangements results in an overlapping of the reflectors of adjacent lighting arrangements. In consequence, the shape of the reflectors needs to be modified so that they deviate from the parabolic shape in sections in which at least two adjacent reflectors contact each other (reflector contact sections). Deviations from the parabolic shape result in the generation of undesired stray light. It therefore would be beneficial to provide an improved aircraft head light comprising a plurality of lighting arrangements which reduces the problem of stray light, but which still allows for a dense packing of the lighting arrangements.
A home daily activity simulation model for the evaluation of lifestyle monitoring systems. Lifestyle monitoring (LM) technology is part of a new generation of telecare which aims to observe the daily activities of older or vulnerable individuals and determine if a medical or care intervention would be beneficial. The development and validation of new LM systems should ideally involve extensive trials with users in real conditions. Unfortunately, effective user trials are very challenging, generally limited in scope and costly. In this paper, a simulator is proposed that can serve to generate synthetic data of daily activity which can then be used as a tool for the validation and development of LM systems. The most challenging part of the simulator is to replicate people's behaviour. In the paper, a novel model of daily activity simulation is proposed. Such daily activities are dependent on a number of external factors that control the need or desire to perform the activity. The proposed simulator aims to reproduce behaviour such that the probability of performing an activity increases until the need is fulfilled. It is possible to parameterise the behavioural model according to a set of features representing a particular individual. The simulator parameters have been populated using real world experiments through hardware testing and data collection with older people. Experimental verification that the desired features are reasonably reproduced by the simulator is provided.
Porphyria cutanea tarda in three generations of a single family. We examined conjugal and blood relatives of one kindred for evidence of porphyria cutanea tarda. The disease was identified in eight family members in three generations. Four were classified as having overt porphyria cutanea tarda because of four criteria: photo-enhanced dermatosis; excessive urinary excretion of uroporphyrins; characteristic thin-layer chromatographic pattern of urinary porphyrins; and decreased activity of erythrocyte uroporphyrinogen decarboxylase. Two patients with excessive excretion of uroporphyrins or characteristic chromatograms, or both, and decreased uroporphyrinogen decarboxylase activity were classified as having subclinical porphyria cutanea tarda, and two with decreased uroporphyrinogen decarboxylase activity only were classified as having latent porphyria cutanea tarda. This study provides further evidence that prophyria cutanea tarda can be a familial disease inherited in an autosomal dominant fashion. We propose a reclassification of porphria cutanea tarda as an overt, subclinical or latent disorder.
The background description provided herein is for the purpose of generally presenting the context of the disclosure. Work of the presently named inventors, to the extent it is described in this background section, as well as aspects of the description that may not otherwise qualify as prior art at the time of filing, are neither expressly nor impliedly admitted as prior art against the present disclosure. Determining the successful operation of various hardware associated with the engine typically requires several sensors for determining the states of the various types of hardware. Providing separate sensors for each of the different parts of the engine increases the overall cost of the engine and, therefore, increases the cost of the vehicle. Automobile manufacturers are under increased pressure to reduce costs while providing a reliable vehicle. One sensor that may be used within a vehicle is an in-cylinder pressure sensor. The in-cylinder pressure sensor provides feedback for operating the engine. The in-pressure sensor signal may have a significant amount of noise. Low-pass filtering with a band pass filter may attenuate the signal to unacceptable levels so that sufficient pressure data may not be obtained.
Genetic and life-style determinants of peptic ulcer. A study of 3387 men aged 54 to 74 years: The Copenhagen Male Study. In the Copenhagen Male Study men with the Lewis blood group phenotype Le(a+b-), non-secretors of ABH antigen, and men with the O or the A phenotype in the ABO blood group have been found to have a significantly higher lifetime prevalence of peptic ulcer than others. We investigated the importance of the association of these genetic markers, life-style factors, and social class with lifetime risk of peptic ulcer, testing specifically the hypothesis that the strength of the association of risk factors with peptic ulcer depends on genetic susceptibility. Three thousand three hundred and forty-six white men 55-74 years old were included for study. From a questionnaire validated during an interview information was obtained about life-style factors and peptic ulcer history (gastric or duodenal). Potential non-genetic risk factors examined were smoking history, alcohol consumption, physical activity level, consumption of tea and coffee, and use of sugar in tea or coffee. Three hundred and eighty-four men (11.5%) had a history of peptic ulcer; 120 (3.6%) had had an operation due to peptic ulcer. Non-genetic peptic ulcer risk factors identified were ever having been a smoker, use of sugar in tea or coffee, abstention from tea consumption, and low social class. On the basis of these and the genetic factors, it was possible to identify a low-risk group (n = 142) with a lifetime prevalence of 4.2%, several intermediate-risk groups, and a high-risk group (n = 55) with a prevalence of 29%; the odds ratio with 95% confidence limits (OR) was 9.3 (3.4-25.3). Corresponding values with regard to operation were 1.4% and 20.0%; OR = 17.5 (3.7-82.0). Several significant interactions were found; for example, the use of sugar was associated with peptic ulcer risk only when interacting with genetic risk groups. Considering the role of Helicobacter pylori, it is interesting that the factors identified in this study were able to identify groups with extremely different lifetime risks. This finding and also the finding of strong interactions between genetic and life-style factors and between genetic factors and social class for the risk of peptic ulcer may have both public-health and clinical implications.
"Previously on Justified..." "This is supreme bullshit." "You do know that we're not allowed to shoot people on sight anymore?" "I'm gonna reassign you." "Eastern District of Kentucky." "I don't wanna go back there." " Still got family here in Kentucky?" " Ex-wife here." "Next time I see you, I'm gonna..." "Fire in the hole!" "How well did you know Boyd Crowder?" "Boyd and I dug coal together when we were 19." "Did you know Boyd's brother?" "The girl he married, Ava." "She ended the union last night with a.30-06." "I had a crush on you from the time I was 12 years old." "...that you get out of Harlan County by tomorrow noon" " or I'm gonna come looking for you." " Now you're talking." "I guess I just never thought of myself as an angry man." "Honestly, you're the angriest man I have ever known." "Looks like it hurts." "Why, yes, Raylan." "Thank you for noticing." "Somebody shot me in the chest the other day." "You getting something for the pain?" "Well, I can goose it as needed, but I've been holding off." "I was hoping that you'd stop by." "I wanted my mind clear and my mouth not all full of rubber when I saw you." "Let's hear it." " What do you think I'm gonna say, Raylan?" " I wouldn't know." "You know, if Ava hadn't come in that room and distracted me with that rifle, you think I could have got you first?" " I don't know." " Well, it don't matter." "The real question is, why didn't you kill me?" "Did you miss my heart on purpose?" "No." "I was aiming to kill." "That's the way I was taught." "Sometimes you don't hit the bull's-eye." "No, I suppose not." "But, you see, I have this belief, this conviction that it wasn't just an accident and that, I was wondering if the fact that we were friends, if that played any part." "Then last night I woke up, and I knew why you didn't kill me." "I was laying here in pain, in awful pain." "But I didn't hit the pump because I knew it wasn't just pain from a gunshot wound." "It was something deeper." "It was a pain from my very soul." "And I realized that, well, I couldn't any more blame you for my situation here than a farmer could blame his neighbor for a hailstorm." "A hailstorm being an act of God." "That's right, Raylan." "Me shooting you was an act of God?" "Well, God was acting through you, Raylan, through your gun, to get my attention, to set me on a new course." "Now, I know not yet what his will for me is, but I have faith." "I have faith that the path will be illuminated before me as I need it to be." "For even through this searing pain, I am at peace." "For I am born again in the eyes of the Lord, Raylan." "And I wanted to thank you for playing your part." "Now, if you will excuse me," "I must tend to the needs of the flesh." "You understand?" "Raylan?" "Did you come all the way out here just to see me?" "What do you think?" "Initial here, here, and here." "Stand up." "How come?" "We're gonna play pin-the-tail-on-the-donkey." "Just stand up." "Come through and stand on the feet." "You got your feet on backwards?" "Turn around." "Just checking you for visible injury." " All's I see is the nose." " Which I got when he hit me with a shotgun barrel for no good reason." " Is that how you remember it?" " You should thank him." "That nose's the only reason you got to spend two days here instead of going straight to Big Sandy." "Hey, careful with the teeth." "You got any more Marshals in the car?" " Task force is undermanned, just me." " Want to put him in leg irons?" "I think I can handle Mr. Crowe." "Marshals drive Lincolns now?" "Or is this confiscated?" "Yeah, I had a Town Car myself one time when I was down visiting Cousin Dale in Florida, till I sold it for parts and went to work at Disney's." "You know what I tried out for?" "To play Goofy..." "Mickey Mouse's friend." "Only, you had to water-ski." "I couldn't get the hang of that, so they put me selling ice cream." "But Disney's got a lot of Negroes and homosexuals working there," " so I came back home." " If you're gonna talk," "I'm gonna put you in the trunk, and I'll drive myself." "You grew up in Harlan, huh?" "I grew up in Corbin." "You ready for this?" "My dad has never been outside of Kentucky." "Whole life, never been closer to the border than Parisville, where he is now." "You know, we're gonna be going by there." "If we was to get off on Route 9, we could stop by and see him." "It wouldn't be more than a few miles out of our way." "What do you say to that?" "Not much, huh?" "Your old dad's never crossed the state lines, but he's been up to Manchester, hasn't he?" "He's seen the inside of the Kentucky State Prison." "You got an uncle who came out of there, and another did his time in McCreary." "I think we'll skip seeing any of your kin this trip." " My uncles are both dead." " By gunshot, huh?" "You understand how I see your people?" "Put one on your left wrist." "Now snap the other one to the wheel." "To the wheel, Chinatown." "Let's go." "I can't drive handcuffed to the damn steering wheel." "You'll get the hang of it." "Now drive." "You gonna report what I did?" "I don't take what you did personally, you understand?" "Want to lean on you." "Or wish you get any more time than you deserve." "But what you'll have to do now is ride the rap, as they say." "It's all anybody has to do." "Let's go." "Come on down, fellas." "All right." "Next." "Where the hell did they get these stupid costumes, anyway?" "Shit." "Well, this is an embarrassment." "Piss and moan all you please, Cooper." "This is what they want to see." ""Hey, Martha, look." "They're making fun of themselves."" "They eat that shit up." "All a part of what sells the CDs." "Of which we don't get one red cent." "Now, you want out, buddy, you just say the word." "We'll be out here, playing parties, eating good food, looking at pretty women." "You can be back at the tiers, making yourself another chess set out of cardboard, huh, Henry?" "I heard that." "And if they wanted suit and ties, we'd be wearing suit and ties." "All right." "Let's head on out." "Free Bird!" "Hell, these horses live better than most people I know." "Hey, Price, you're not eating?" "No, Henry." "You have at it." "Hey, Henry, I got to take a leak." "Coop's already in the Porta-Potty." "Use a tree." "Hell, Henry, now, that ain't civilized." "You're back on." "We're gonna start with the cake and Happy Birthday." "Price, let's go." "We got to get back out there." "Come on, Henry." "I really got to drain it." "Come on, Cooper!" "Let's go!" " Hey, Henry." "What do you want to do?" " You walk them out." " I'll bring these two." " All right." "Come on, Coop." "They want to do Happy Birthday now." "Coop!" "Stand over there." "Coop, open this door." " Open this door!" "Come on, Coop!" " Hey, Henry, watch this." " Hello, Art." " Where are you?" " Just heading back." " How far are you from the prison?" "Not far." "Just passed through Parisville." "Well, I want you to go back." "They had a breakout." " No shit." " There was a bluegrass convict band that was playing a birthday up near Parisville, and the bass player and the drummer decided to make a run for it, so I need you to go back up to Big Sandy and," "you know, check their cells, see what you can find." "I sent a couple of deputies up to Parisville." "And get this, the bass player was about to be released in 3 months after a 15-year stretch." "You got some names?" "They couldn't have gotten very far." "See what you can find out." " Evening." " Evening." "You..." "You need help with something?" "No, I'm just looking for some road food." "There's no way in hell you're gonna be able to draw and fire before your head comes off." " I could get him." " Fine with me." " What?" " Set your weapon down on the ground, please, sir." "And your backup." "Kick them back this way." "On your belly." "Hands on your neck." "See, I told you." "Turn the light on, we'll get us a car." " Got us some more guns, too." "Give me one." " Oh, no." " You're gonna run." " What?" "As far and as fast as you can, 'cause I swear to you, if I ever see you again, I'll kill you." "But we just busted out of the damn joint together." "You got five seconds." "What is this, a joke?" "Shit!" "All right." "You can sit up." "Wallet, ID, keys, hand them over." " What are you, state police?" " US Marshal." "Marshal?" "Like in Gunsmoke?" "More like The Fugitive." ""Deputy US Marshal Raylan..." ""Givens."" "I knew a fella up in Manchester named Givens, Arlo Givens." "Any relation?" "I suppose there's still some." "He's my father." "No shit." "And here you've become a US Marshal." " How'd that go down with him?" " I wouldn't know." "Now take your handcuffs out and cuff your hands behind your back." "So, you Cooper or Price?" "I'm one of them." "Fine." "I'll wait and find out tomorrow when your picture's in the paper." "My name is Douglas Cooper." "Glad to meet you." " You didn't care so much for Price, huh?" " Get on your feet." "What was he in for?" "His real crime?" "Being a lousy drummer." "He's not incompetent." "The man could play a paradiddle, but he's showy, has no sense of time." "How can you tell there's a bad drummer at your door?" " I don't know." "How?" " The knock speeds up." "Nice." "You a musician?" "No, just someone who likes music." "Yeah, and shitty jokes." "Come on." "Let's go." " And what were you in for, Mr. Cooper?" " I expect you know that already." "Fifteen years is a long time for one bank job." "Well, the thing is, a fella died as a direct result." "Foreseeable circumstances." "But, honestly, if you hire a moron for a driver, it's foreseeable." "You taking my badge and my car to get past any roadblocks, huh?" "And your hat." "Good night, deputy." "Good night, Mr. Cooper." "Well..." "Shit." "Come in." "Come in." "Now, let me get this straight." "He took your gun..." "Sorry, two guns." "Your badge, your car, and your hat." " He take anything else?" " Not that I can remember." "He didn't rape you, did he?" "We found your car at the airport, which means that Cooper either left town or he wants us to think that he left town." "We found this in the trunk." "That look familiar?" " You didn't find any guns, did you?" " No." "Sorry." "The dogs chased Price into a culvert, and then Rachel talked to him." "She and Tim can bring you up to speed." "All right." "Raylan, just a second." "Shut that door." "I got a call this morning from AUSA David Vasquez." "Wants to talk to you about your shooting Boyd Crowder." "Well, what's there to talk about?" "He pulled first." "There was a witness." "But, you see, 10 days ago, you shot a man in Miami." "Put it like this." "If you was in the first grade and you bit somebody every week, they'd start to think of you as a biter." "He also wants Ava to come up to Lexington to talk about it." " Well, fine with me." " Which part?" "The part about her talking to Vasquez or the part about her coming up to Lexington?" " Raylan, you can't sleep with her." " I know." " Raylan..." " I won't." "You starting to regret me coming here?" "Not yet." "Price says the only reason why he helped Cooper escape is because Cooper promised him a lot of money." "Which could be from his last job." "He got away with $180,000." "Never recovered." "Tell me about the dead driver." "He was a Mensa candidate named Drew Baxter." "A few hours after the robbery, Cooper and Baxter headed out of town." "Baxter's driving." "They get pulled over for a traffic violation." "Baxter decides to floor it." "Hilarious hijinks ensue." "Baxter drives head-on into a tree, goes through the windshield, and into the afterlife." "And it all fell under commission, so Cooper got charged with his murder." "So, why is he breaking out with only three months left on his bit?" "I mean, has he got a daughter getting married or a granddaughter graduating school?" "No kids, and his mother and father passed." "He was married when he went inside." "Younger woman, one-time exotic dancer, named Shirley Kelso." "Didn't divorce until five years ago." "Still lives in town." "I thought I'd go have a word." "I'm gonna take a team and check acquaintances." "I'm gonna go with him." "Nothing against acquaintances, but one-time-exotic-dancer Shirley sounds a little more fun." "What the hell did you say to him?" "I'll catch up with you at the car." " Hello, Winona." " What did you say to Gary?" "I believe I said, "Hi, Gary."" " Why?" "Why did he say I said?" " He didn't." "Just he didn't sleep the rest of that night, and the next morning, he was still shaking." "And every night since then, he checks the windows, and he checks the doors, and then he checks them again." "I don't know." "Winona, does Gary spook easy?" "What are you implying?" "You wouldn't be startled if somebody broke into your home in the middle of the night?" "I'm not implying anything." "I heard you got jumped by an old convict." "Does 55 still seem old to you?" "Are you gonna shoot him if you catch him?" "All right, look, I won't show up unannounced anymore." "You won't show up at all anymore." "Art tells me you were a sniper with the Rangers." "Yeah, I was." "What's the longest you ever had to watch a target?" "Three days." "Shitty little village outside Kandahar." "You watch a man that long, you can get to know him better than his wife does." "How he reads the paper, picks his nose, what glass he likes for tea, what one for milk..." "If he jerks off, what he looks at when he does." "If he's nice to the dog when no one's around." "What's the trick to something like that?" "Keeping your focus?" "Well, they told us to come up with stories about ourselves and the target." " What do you mean, "stories"?" " Well, nothing elaborate." "Imagine taking Shirley to the movies, watching Price is Right, eating takeout Chinese." "They eventually stopped that, the business with the stories." "Why is that?" "They found some folks get so involved in the tales they're telling themselves, they grow to like the target." "And when they got the green light, they couldn't pull." "That ever happen to you?" " Is that her?" " Looks like it." "US Marshals." "Shirley Kelso?" "You think he's here?" "You're welcome to look around." "Who's this?" "They're with the Marshals." "I'm guessing they're looking for my ex." "My cousin Dupree." "He's staying with me till he gets on his feet in construction." " Y'all want a beer or something?" " Yeah, love one." " Pabst, Schlitz, Mickey's..." " It was a joke." " We can't have a beer." " Well, I don't want your job, then, do I?" "Either of you seen or heard from Douglas Cooper?" "You mean since he broke out or since ever?" "Since last night." "No, and I swear to you, you give me a card or a number and he turns up, you'll be the first person I call." "Marrying him was the biggest mistake of my life." "You stayed married to him till five years ago." "There were tax advantages." "Any idea why he'd bust out with just a few months left on his bit?" "None at all." "I mean, you ask me, he's long gone." "I mean, there is nothing for him here." "When's the last time you saw him?" "Before the divorce, yeah." "What do you think?" "Sure made a big deal about running down her ex-husband." "Of course, that might have been for Dupree's benefit." "You don't think they're cousins?" "Maybe, maybe not." "Either way, she's banging him." "That's got to suck." "To break out of prison, expecting a blissful marital reunion." "I got to think, no matter how long you've been divorced, seeing your old lady shack up with someone else is gonna annoy the shit out of you." "If Cooper does show up, you sure as hell won't call the number on that Marshal's card." "Oh, yeah?" "Well, Coop might not be so happy to see us, you know?" "Who gives a shit?" "He's the only one who knows which house to go into." "It doesn't matter." "I hope he shows up." "I'm glad you feel that way." "Sit down." "Take a seat right there." "How'd you pick the houses?" "I saw reports on the TV in prison about somebody breaking into houses in Riverbrook, tearing up the floors." "Now, I know you haven't found the money yet." "I knew that the minute I saw this shit hole." "How did you pick the houses?" "You told me you hid the money in a house under construction in a development, and I just figured out it had to be Riverbrook." "Picked the houses at random?" "Well, you always said your lucky number was 3-2-3, so we went for houses with 3-2-3 in the address." "Y'all sleeping together?" "We're cousins!" "Well, from all the lotions, condoms, and devices I saw sitting on your nightstand, it's clear you're sleeping with somebody." "Well, it ain't like we're first cousins or anything." "There's no need to hide it from him." "He already knows." "There was one device, kind of a vibrating thing with ball bearings going all around, making it wobble all over." "That's Randy Rabbit." "It's our best seller." "If I'd known you wanted something like that, I'd have got it for you back in the day." "I was 22 when you went in." "You were the first man I ever slept with." "I didn't know what I wanted." "Hey, we can all have a real interesting conversation later about the merits of various sex toys, but right now, maybe we ought to focus on how we're gonna get you out from under the eyes of that Marshal." "And what's all this "we" shit?" "I'm just here to make sure you hadn't already found the money." "Yeah, but we can help." "We got tools." "We got pry bar, a Sawzall." "Fine." "I'll take 'em." "How you gonna get out?" "You know they got Marshals watching." "I'll wait till after dark, and I'll sneak out back." "You're gonna walk to Riverbrook?" "I got a car." "I'll steal one." "You know, you just leave us, what's gonna stop us from just calling the Marshal?" "Good point." "Maybe I'll just kill you." "I'm not gonna kill you." "And you aren't gonna call that Marshal and get sent away for all them burglaries you've done." " You know how to bypass burglar alarms?" " I do." "Burglar alarms that have come along in the last 15 years?" "Fiber optics, net-based?" "I was an alarm installer before." "How do you think we got in and out of all those houses without getting caught?" "All right." "You're in." " All right." " 10%." " Shirley, too." "We're a team." " Fine." "But you share the 10%." "Now, why don't you run out on the porch and sit down for a spell and keep an eye on that Marshal." "Cousin Dupree?" "Yeah, I'll do that." "I know you must be angry, but I swear I kept my knees together for 10 years after you went in." "Finally, I realized I had to live." "Baby, I understand that." "Frankly, I'm surprised you hadn't gone after my money before now." "Well, we only went after it now 'cause we had to." "Folks in Riverbrook, they've been remodeling instead of selling 'cause of the downturn, and we just didn't want someone to stumble on it." "That's all." " That was the reason, huh?" " Yeah." "Nothing to do with me getting out in three months." "I told Dupree about it a couple months ago, and he knows alarms and all, and he just thought we should try it." "You know, Dupree has ambitions, plans." " For what, a chain of dildo stores?" " Not just dildos." "Ava." "I told the manager I was your girlfriend." "I'm not being presumptuous and saying that I am." "I just wanted to surprise you." "And you did." "I can't sleep with you, Ava." "Now look who's being presumptuous." "I know about the assistant attorney who wants to talk to you." "I can't be getting amorous with a witness in a shooting I was involved in." " Couldn't we just make out a little?" " No." "You want me to drive back to Harlan?" "You can stay." "I could always sleep on the floor." "Well, it's your bed." "I'll take the floor." "Can we just put on a little music and dance?" "Do you know why the Pentecostals don't have sex standing up?" "It could lead to dancing." "People talk about cars having a new-car smell." "This car has an "old car somebody died in" smell." " You had a car somebody died in." " You mean Baxter?" "Technically, he died outside the car, when he hit the tree." "No, I'm not talking about Baxter." "I'm talking about the red car." "My Lord." "That '71 Valiant." "I called it the Rocket." "The Rocket." "That's right." "He told me he got it cheap 'cause the old guy who owned it died in it and no one wants to buy a dead man's car." "And I kept joking maybe it was haunted." "And then we went for a drive in the country, you know, windows down, breathing in the night air." "And all of a sudden I hear this moaning sound, this..." "You know, like a ghost." "And I about shit a brick." "And this one can't stop laughing." "And then he shows me a tape recorder under the seat playing him sounding like a ghost." "Can you believe that?" "Y'all want to keep jawing about the old days, or y'all want stay on the money train?" "What address are you looking for?" "I'm not." "When I stashed the money, these houses were still being built." "They didn't have addresses." "Then what are you looking for?" "You were onto something with my lucky number, 3-2-3." "But it's not in the address." "Are you gonna tell us or not?" "All right." "The first thing they built out here was that school we passed back yonder." "Now, that was my starting point." "I took the third right and the second left, and the third house on the right, 3-2-3." "Which puts it right here." "No burglar alarm." "Apparently, I didn't need your help after all." "About as much as we needed your car-stealing skills." "Well, I stole one." "Could have rented one faster, and it wouldn't have smelled like a grave." " Keep it up, and your 10% is gonna be 5%." " Whatever you say, old man." "You guys want to argue, or you want to find some money?" "Come on, Martha Stewart." "Just drop that." " Here we go." "Right here." " I'm coming." "Maybe you counted wrong." "I counted right." "Maybe you counted wrong 15 years ago." "I didn't count wrong, not then, not now." "The only possibilities are some other folks found the money and are long gone or that school got up and moved somehow." " Now, which do you think is more likely?" " Let me get this straight." "After all this time, you don't have any idea where that money is?" " No, I guess I don't." " Well," "I guess we don't really need you then, after all, do we?" "Come on." "Let's go." "I'm sorry." "You were gone so long, I just couldn't wait." "I'm sorry." "You look good, Coop." "Come on!" "We've got some shit to do." " Do you know where the money is?" " Well, I do now." "Where are you going?" "I ain't getting in that shit heap again." "We get the money, we'll take ourselves another car." "Ain't nobody gonna stop us." "Now, come on." " Raylan?" " I think I know where Cooper's money is." "Come on, baby." "We're gonna get that money, I'm gonna buy you anything you want." "Shit." "Got to ask." "Why the hat?" "Honestly," "I tried it on one time, and it fit." "Oh, shit!" "You don't do exactly as I say, you're gonna get two in the chest and one in the head!" "You boosted a Gremlin?" "Oh, hell, with all the alarms and stuff they got on cars these days, that's all I could get." "I tried to get a Mustang." "So, what happened?" "They take the money and run?" "No." "There wasn't any." "Well, why'd they shoot you?" "I don't know." "I don't care." "I thought I broke out 'cause of the money, but then I saw Shirley." "Well, maybe Dupree figured out where the money is." "Well, I don't see how." "I told him either the money was here and somebody found it and took off or that school up and moved." "Yeah, I knew where the money was in relation to the school." "Which one?" "We passed two driving around." "Oh, shit." "Fifteen years is a long time." "I told you we shouldn't have taken the money." " You enjoyed it just as much as I did." " Shut up!" " How'd you find it?" " Well," "Mr. "I'm too cheap to hire a plumber" tried to put in a new dishwasher and flooded the entire place, and then we had to replace the floor." "Oh, yeah, I'm an idiot." "But if it wasn't for me, we never would have found the money." "And we wouldn't be sitting here now!" "Where was all your second-guessing when you got your new boobs?" "You enjoyed them a hell of a lot more than I ever did!" "They're very nice." " Thank you." " Shut up!" "Now, I want what's left of the money right now, or I start shooting." " There is none." " I'll start with you." "No!" "No!" "He's telling the truth." "After the boat and the car and my boobs and the TVs, it's all gone." "Man." "He's got them tied to chairs." "We take the back." "Rachel and Raylan, you take the front." " You got a story for Cousin Dupree?" " Yeah." "But it's pretty simple." "If he does anything out of line, I get to shoot him." "That's a good story." " How much those shoes run you?" " Seven hundred." "$700 for a pair of shoes?" "They're alligator." "Got your alligator's attention?" "We'll get you every last cent we have!" "Just please don't shoot anymore!" "My foot!" "Shirley, untie the woman." "She might could take us to the bank." "Okay." "No." "Shit." "Stop." "The banks ain't open this hour." "Shit!" "Let me think." "US Marshals." "I was wondering if I could come inside." "No, you can't come inside!" "Dupree, this isn't your home." "Mr. Lonner, may I come inside?" "God, yes!" "Come inside!" "Hey, you ain't calling the shots here." "Just coming inside to explain things to you." " There ain't nothing to explain." " Ten seconds." "Huh?" "Dupree, can you just keep your gun down for 10 seconds?" "I can tell you both what's what." "You can see my hands." "All right?" " All right." " All right." "You mind standing where I can see you?" "Now I'm gonna give you a choice." "You won't like it, but it's real simple." "If you raise your gun again, you're dead." "Aim at the family, you're dead." "If you move too fast from where you're standing, dead." "In fact, I'd say dropping your weapons and putting your hands behind your head's the only viable option, but that's your choice." " Well, we got guns and hostages here." " I see that." "Do you really think you can draw and fire before one of us pulls the trigger?" "This ain't about me." "This is about Deputy Tim Gutterson, sniper in the Afghan War." "Well, I don't see him." "You got a little sniper in your pocket?" "Well, he's out back, across the street there." "He bullshitting?" "Well," "I see cars and people." "I don't see a sniper." "No, no, no, no." "He's there, or I wouldn't be here." "Where's the light switch for this room?" "Now, Dupree, I know that wasn't on the list, but..." "Where's the goddamn light switch?" " On the wall, by your friend." " Shirley, find that switch." " Shirley..." " On the count of three, flip the switch." " Shirley, don't do it." " One, two, three!" "Why'd you turn the light back on?" "He had no need to shoot my husband." "Initial here, here, and here." "Going solo again?" "Another deputy in the car." " Learned your lesson?" " Until I forget." "Stand up, walk through." "Put your feet on the feet." "You know the drill." " How's the gut?" " Well, they tell me my plumbing's okay, but every which way I move hurts." "I think we're good." "Did you find the money?" "The couple in the house found it." "They enjoy it?" "They bought a lot of stuff." " Have you seen Shirley?" " I'm sorry, I haven't." "I know she's in custody." "But she helped you guys nail Dupree, right?" "That ought to count for something." "She's still gonna pull some time." "Maybe we'll get out about the same time." "Maybe." "Maybe." "Man." "She looked good."
The present invention is directed to a soil separator for a dishwasher and particularly an arrangement between a soil separator chamber and a soil accumulator chamber which provides an improved apparatus and method for collecting and filtering soil from dishwasher water. A known arrangement for removing soil from dishwasher water is described in U.S. Pat. No. 5,165,433. This apparatus includes a combination motor-pump and soil separator assembly. The motor-pump assembly includes a wash impeller, which operates within a pump cavity located within the soil separator. As the impeller operates in a wash or rinse mode, a swirling motion is created in the wash liquid passing through the pump cavity, thereby creating a centrifugally sampled annular layer of wash liquid on the annular interior wall. A portion of the wash liquid having a high concentration of entrained soil (food particles, etc.) passes over an upper edge of the annular interior wall and into an annular guide chamber. Wash liquid from this guide chamber travels to an annular soil collection chamber at a high flow rate. This high flow rate is achieved by use of a relatively small aperture located in a lower portion of the annular wall separating the guide chamber and the soil collection chamber. Upon entering the soil collection chamber, wash liquid flows outwardly and upwardly through a screen which separates the water from the soil. The wash liquid is prevented from draining out of the soil collection chamber by a ball check valve seated within a drain port. The screen contains an annular arrangement of fine mesh filters, which prevent soil particles entrained in the wash liquid from reentering the dishwasher space. The cleansed wash liquid returns to the dishwasher floor where it is picked up by the motor driven pump for recirculation within the dishwasher. Typically, the apparatus such as described above allows water to pass through the hole between the guide channel and the collector chamber at a rate of about 4 gallons per minute. This flow rate can cause the heavily concentrated mixture of soil and water within the accumulator chamber to be agitated, preventing soils from readily settling. With this flow rate and configuration, there may be a tendency for the mechanical filter to clog even though back wash nozzles for spraying the filter from above are provided. Collecting soil at these flow rates cause filter screens with a 0.0049 inch mesh to have a tendency to clog. It was necessary to increase screen mesh to 0.0079 inch to prevent this clogging. However, the larger mesh screen allowed soils of larger particle size to escape through the screen and may be seen as xe2x80x9cgritxe2x80x9d on the dishes. It is an object of the present invention to provide a dishwasher soil collection system which is compatible with a high flow rate soil removal dishwasher while at the same time allowing for adequate screening of soil in the dish water return to the dish compartment in a recirculating dish water system. It is an object of the invention to provide a more efficient method of soil collection and retention while reducing water and energy usage. The objects are inventively achieved in that an annular soil separator wall is provided around the dish washer pump for accumulating solids by centrifugal action, a soil guide channel is provided surrounding the separator wall, and a shallow soil accumulator channel or xe2x80x9cscreening channelxe2x80x9d, substantially annular, is arranged beneath the filter screen surrounding the soil guide channel. The soil accumulator channel is flow connected to the guide channel by a vertical tube at a first closed end of the channel and the channel surrounds the guide channel to an open channel end which empties, to an accumulator sump having a drain port closed by a ball check valve. Water and soil proceed around the accumulator channel, soil is retained beneath the filter screen and water proceeds through the filter screen. Back wash nozzles are provided to wash the filter screen of soil from a dish compartment side of the filter screen. Thus, by directing inlet water from the guide channel to the shallow accumulator channel, the inside of the filter screen is washed by the water, while the outside of the screen is washed by the backwash nozzles above. Therefore, food particles which are temporarily dislodged from the screen by the backwash nozzles may not immediately return to the screen after the backwash nozzle passes, due to the direction of flow on an inside surface of the filter screen from the water flowing inside the accumulator channel. Inlet water flow into the accumulator channel is directed in a circulatory path and kept in the shallow accumulator channel in close proximity with the screen. As particles are dislodged by the backwash nozzles, they are moved around toward the stagnant soil accumulator sump. The sump is located away from the accumulator channel water inlet and therefore, more isolated and stagnant, allowing soil to settle. This is due to the fact that water and soil lose velocity as they approach the accumulator sump while most of the water escapes through the screen. The accumulator sump can be configured more compact when using the shallow accumulator channel of the present invention. The physical configuration of the system reduces water held in the accumulator by 60% or greater.
It is known that polymeric materials must be pretreated before chemical and subsequent electrolytic metallizing, for example by etching the polymer surface using chromic acids. The polymer surface is altered during etching in such a way that caverns and vacuoles are formed. This is only possible with certain polymers, for example with 2-phase multi-component graft polymers or copolymers, such as ABS polymers, impact resistant polystyrene or 2-phase homopolymers, such as partially crystalline polypropylene. Moreover, the application of chromic acid or other oxidants is associated with an impairment of the physical properties of the polymeric base material such as notched impact strength and electrical surface resistance. Further, the hexavalent chromium which is drawn into the activation bath and into the metallizing bath causes these baths to be poisoned. The same disadvantages are encountered in processes in which the polymer surface is chemically altered using a strong gaseous oxidant, for example hot SO.sub.3 vapour. The conventional processes for non-electrical metallization of materials usually comprise relatively many process steps and also have the disadvantage that they are limited to substrates which may be chemically or physically roughened due to their physical form or chemical structure. EP-A 0,081,129 further discloses that an activation which produces strongly adhering metallic coatings is achieved by "swelling adhesion nucleation." This elegant process has the disadvantage however that it causes stress cracking in complex shaped polymeric injection mouldings. Further, this process requires a new swelling activation system for each type of plastic and thus is not universally applicable. Finally, US-A 3,560,257 and 4,017,265 and also DE-A 3,627,256 disclose processes for activation, which use activator solutions containing adhesion promoting polymers. The disadvantage of these processes is that they require the use of relatively high concentrations of expensive precious metal activators. An object of the present invention was thus to develop an economic process for chemical metallizing, by which material surfaces based on all commercial plastics can be given a strongly adhering metallic coating deposited by wet chemical methods without previous etching with oxidants. The object can be achieved by coating the substrate surfaces with a primer based on a polymeric organic film former.
The present invention relates to a fryer for cooking food, and more particularly to a multipurpose fryer having a auxiliary container provided at a side of the fryer to fill water therein, whereby can supply drinking water or washing water that is heated up by heat release from the fryer, which can be used to boil and to keep boiling the food by utilizing additional a cooking pot, and which may be used for supplier hot water if circumstances require. The fryer for home-life or professional is typically formed cubic or cylindrical, which heated up the oil therein to fry the food by 160 to 220xc2x0 C., using such a method that there is installed gas burner beneath the fryer or installed heater inside it, whereas fragmentary chips of frying food is collected on the bottom of the fryer. The common fryer is simply used to fry the food with hot oil, and therefore the heat release therefrom is wasted without reuse, causing excessive energy consuming. Therefore, the present invention is designed from this viewpoint, it is the object of this invention to provide a multipurpose fryer for saving energy by using heat release from the fryer to heat up contained water in an auxiliary container, which can be used to supply drinking or washing hot water, and be used to boil and keep boiling the food by utilizing an additional cooking pot, and which may be used for supplier hot water if circumstances require. To achieve the above object, there is provided a fryer comprising, a heater arranged in lower portion in the fryer; a net screen arranged over the heater; and a control unit arranged at an upper portion on the fryer, which is connected to both terminals of the heater to control the power supply; characterized by, a space formed on an inclined mid-bottom of the fryer, which has an outlet communicated with a valve provided on an outer side of the fryer; and an auxiliary container defined as space beneath the mid-bottom and upper portion of end-bottom of the fryer and is extended to vertical direction along the side wall of the fryer, wherein its open portion is disjointably fitted by the control unit, its inside is provided with a auxiliary heater connected to the control unit, and a side of its lower portion is communicated with another valve provided on another side of the fryer. According to another aspect of the invention, there is provided a fryer further characterized by being combined fitably an additional cooking pot with its lid to be used to boil and keep boiling the food, as well as the fryer is used to cook the frying food with oil.
Molecular characterization of the EGF receptor and involvement of glycosyl moieties in the binding of EGF to its receptor on a clonal osteosarcoma cell line, UMR 106-06. The epidermal growth factor receptor in cells of the UMR 106-06 clonal osteoblast line has been shown to be structurally similar to that previously characterized in other cell lines. A specific receptor component of approximately 165,000-185,000 Mr has been identified by polyacrylamide gel electrophoresis using the chemical crosslinker disuccinimidyl suberate to crosslink 125I-EGF to its receptor. Tunicamycin treatment of cells resulted in a dose-dependent loss of binding suggesting involvement of glycosyl moieties in EGF binding to its receptor. Competitive binding studies carried out using wheat germ lectin (WGL), concanavalin A (CON.A.), soybean lectin (SBL), and lentil lectin (ILL) to compete for binding of 125I-EGF revealed that CON A, WGL, and to a lesser extent LL could inhibit EGF binding; SBL was without effect. Treatment of the cells with neuraminidase which cleaves terminal sialic acid residues resulted in total loss of binding while alpha-glucosidase, beta-N-acetylglucosaminidase and alpha-mannosidase were without effect. These data indicate a specific interaction of EGF with terminal sialic acid residues of the EGF receptor. However, it would seem that the mannose residues which appeared to modify EGF binding were not available for the action of the above enzymes due to the presence of sialic acid.
This invention relates to apparatus for eliminating time base errors in an information signal and, more particularly, to such apparatus which finds ready application in conjunction with a color video signal which is reproduced from a record medium, whereby time base errors which may be present in the chrominance component of the color video signal are eliminated. Various devices have been developed for the recording and reproduction of signal information, and particularly video signal information which has a composite color video signal. Examples of such devices include the video tape recorder (VTR) wherein one or more rotary heads scan successive parallel skewed tracks across the surface of a magnetic tape for recording and/or reproducing color video signals from such tracks, magnetic sheet recorders wherein a magnetic sheet is used as the record medium upon which color video signals are recorded in parallel record tracks, and a video disc recorder wherein video signals are recorded in a spiral track or in substantially concentric circular tracks and are reproduced from such tracks by magnetic recording/reproducing apparatus, optical apparatus, and the like. The problem of time base errors in the video signals which are reproduced by the above-mentioned devices is generally common to all of such devices; and to facilitate an explanation thereof, the following discussion is directed specifically to VTR's. In a typical VTR, the luminance and chrominance components are separated from the color video signal and are processed in separate channels wherein the luminance signal is frequency modulated to a relatively high frequency band while the chrominance component is frequency-converted to a lower frequency band which is below the FM luminance band. These separately processed components then are recombined and recorded simultaneously in successive, skewed record tracks. During a signal reproduction operation, the FM luminance and frequency-converted chrominance components are separated from the reproduced color video signal and are respectively demodulated and frequency reconverted back to their original frequency bands. Then, the recovered luminance and chrominance components are recombined to form the composite color video signal. In general, the reproduced color video signals contain time base errors, so-called jitter, due to mechanical vibrations in the tape transport mechanism, fluctuations in the rotation of the heads, errors in the speed at which the tape is transported, stretching or shrinkage of the tape since the video signals had been recorded thereon, and other parameters and conditions which will cause time base errors. While these errors typically have only a negligible effect upon the luminance component of the reproduced video signal, they have a particularly serious effect upon the chrominance component, whereby the hue of the reproduced color television picture may be distorted. One proposal for eliminating or cancelling such time base errors from the reproduced chrominance component provides an automatic frequency control (AFC) circuit for controlling the frequency of the frequency re-converting carrier which is used in the chrominance channel to reconvert the carrier of the chrominance component back to its original frequency. In this AFC circuit, frequency errors in the reproduced chrominance component are detected, and a variable oscillator, such as a voltage-controlled oscillator (VCO) is adjusted to provide an oscillating signal, from which the frequency re-converting signal is derived, so as to cancel the frequency error. The frequency error is deteched by comparing the frequency of the reproduced horizontal synchronizing signals with the frequency of the VCO output. While this AFC operation generally is effective to eliminate relatively large-scale time base errors, such as those time-base errors which influence the frequency of the reproduced horizontal synchronizing signal, the AFC operation has no effect upon relatively small time base errors which may occur in those line intervals which occur between successive horizontal synchronizing signals. The aforementioned relatively small time base errors appear as fluctuations in the subcarrier of the chrominance component upon which the color information signals are modulated. In one proposal for eliminating such relatively small time base errors, an automatic phase controlled (APC) circuit is used to detect phase errors in the reproduced chrominance subcarrier. In this APC circuit, a highly stable reference carrier is generated and the phase of the reproduced chrominance subcarrier is compared to this reference carrier. In a typical embodiment, the APC circuit is used in conjunction with the AFC circuit, the latter including the aforedescribed VCO circuit, and any phase error which is detected by the APC circuit is used to control the VCO circuit so as to adjust the frequency reconverting signal derived therefrom, whereby such phase errors are eliminated. The reason for providing the APC circuit in conjunction with AFC circuit is to provide adjustments in the frequency reconverting signal in the event that the time base errors which are present in the reproduced color video signal exceed the limited lock-in range of the APC circuit. In one embodiment of a time base error correcting circuit which uses both an AFC circuit and an APC circuit (known as an AFPC circuit), such as the AFPC described in U.S. Pat. No. 3,723,638, the frequency error control signal which is obtained by detecting the time base frequency error and the phase error control signal which is obtained by detecting the time base phase error are added, and the resultant control signal is used to control the VCO. However, there may be some instances when the frequency and phase error control signals tend to attain opposite adjustments in the frequency reconverting signal. This impedes rapid and satisfactory cancellation or elimination of the time base errors. The problem of oppositely acting control signals in time base error correcting apparatus is addressed in copending application Ser. No. 851,408 entitled "Time Base Error Correcting Apparatus" filed Nov. 14, 1977 by Kuniyoshi et al. In this copending application, the VCO is controlled with the frequency error signal produced by the AFC circuit only when the time base error in the reproduced video signal is beyond the lock-in range of the APC circuit. The present invention is directed to another technique for solving the problem of oppositely acting frequency and phase error signals in an AFPC circuit.
Efficacy of porcine placental extracts with hormone therapy for postmenopausal women with knee pain. Knee pain related to osteoarthritis increases with age and is more common in middle-aged women. Although hormone replacement therapy (HRT) improves knee pain, women unresponsive to HRT need an effective adjunctive therapy. The aim of this study was to assess whether oral porcine placental extracts (PPE) have an impact on patients with knee pain as an adjunctive therapy combined with HRT. Forty-eight postmenopausal women with knee pain receiving HRT were enrolled into this open-label, randomized, controlled study. Subjects were randomized into Group 1 (n= 24) or Group 2 (n=24). Subjects in Group 1 were given 3 months open treatment with calcium (260 mg/day) as adjunctive therapy combined with HRT. Group 2 received PPE (9 capsules/day) as adjunctive therapy combined with HRT. Changes in the degree of knee pain were evaluated by the Visual Analog Scale (VAS). Treatment with PPE was significantly effective in reducing the VAS score for knee pain at 4 weeks (p < 0.05), at 8 weeks (p< 0.01) and at 12 weeks (p<0.01), compared with the control group. Interestingly, the effects continued for 4 weeks after cessation of treatment in the PPE group (p< 0.01) compared with the control group. The PPE treatment had no significant adverse effects on blood biochemical and metabolic profiles, especially related to the risk factors for cardiovascular disease. PPE is a possible option as an adjunctive oral supplement in the case of HRT-resistant, long-lasting knee pain.
The present invention relates generally to a child's book stand, and more particularly to a child's book stand which displays books in a forwardly facing orientation. Children below reading age can often select their own books by looking at descriptive pictures on the front covers of books. Therefore, many children's book stands display books in a forwardly facing orientation, i.e. with the front covers of the books facing the child. Double-sided children's book stands which can display books on either side of the unit are known in the art. However, most conventional children's book stands are not adapted to be easily altered in any significant manner in order to serve a multi-purpose function. Furthermore, children's book stands are generally constructed of a relatively heavy material such as wood and thus are not easily transportable. These conventional book stands can be supplied with caster wheels in order to facilitate moving the book stands short distances, e.g. from room-to-room, but their weight still makes it difficult for these book stands to be transported any significant distance. Such book stands are not adapted to be easily lifted in the air and mounted on a wall. In addition, conventional book stands are typically constructed of several panels of wood which are fitted together. It is not possible for a children's book stand that is constructed of wood to be formed as an integral unit. For example, a standard wood-framed book stand is comprised of at least four separate pieces of wood (two sides, a bottom, and a back) in addition to each shelf. Thus, manufacturing and assembling a wood-framed book stand may be relatively complex and costly. Furthermore, most conventional children's book stands have shelves which are either permanently mounted in set positions relative to one another or may be somewhat adjustable to a very limited number of positions. This restriction, in addition to being inconvenient, may limit the height of books that may be displayed. Furthermore, the depth of shelves (i.e. the approximate distance from the front of the shelf to the book stand) in conventional children's book stands is generally not adjustable in size, which may limit the thickness, as well as the height, of books that may be displayed.
It is now well established that putting an infant to sleep on his or her back is the single most important step in reducing the risk of sudden infant death syndrome (SIDS). Recent research also suggests that a baby's risk for SIDS can be greatly reduced by using a pacifier. Medical research also shows that babies who can satiate their natural sucking reflex sleep better. Experts recommend giving babies a pacifier every time they are placed to sleep. The exact reason that pacifiers reduce the risk of SIDS is not known. One suggestion is that the presence of a pacifier in the mouth may discourage babies from turning over onto their tummy because turning or moving may dislodge the pacifier. Another suggestion is that pacifier use and/or the sucking reflex helps keep the tongue positioned forward, keeping the airways open. Yet another suggestion is that pacifiers stimulate upper airway muscles and saliva production, so using pacifiers may keep babies from falling into a deep sleep, which is protective against SIDS. One of the factors that has led to a revival in the ancient practice of swaddling is the practice of putting babies to sleep on their backs as this helps to reduce the incidence of SIDS. However, babies tend to sleep better on their tummies than on their backs. Swaddling has been found to assist infants sleep more comfortably on their backs and to assist in easing colic, which also improves sleep. Swaddling is the practice of wrapping infants tightly in a blanket or cloth so that movement of the limbs is restricted. Medical research has shown that swaddling and sleeping supine (on the back) promotes more efficient sleep, with fewer spontaneous awakenings compared with sleeping supine but unswaddled. Swaddling seems to inhibit each step from sighs through startles to full arousal in the arousal pathway. This results in swaddled babies sleeping longer and being more likely to return to sleep on their own: Swaddling: a systematic review, Bregje E. van Sleuwen, et al, Pediatrics vol 120, number 4, October 2007. To achieve the benefits of swaddling, infants need to be wrapped sufficiently tight to restrain the limbs and inhibit the movements associated with a full startle reflex, which can wake babies from sleep. The startle reflex is seen in infants from birth to around 6 months of age (some sources indicate it can occur in infants as old as eight months). The startle reflex is a natural reflex that babies are born with, and can be triggered by loud noise or sudden movement. In response to the trigger, the baby throws back his/her head, extends out the arms and legs, cries, then pulls the arms and legs back in. A baby's own cry can trigger the reflex. It can also be triggered during sleep, causing the baby to wake. Care needs to be taken not to swaddle too tightly because this can compress the chest and make breathing difficult. There is also an increased risk of overheating especially when the head is covered or when there is infection. Improper swaddling can also lead to a risk of hip dysplasia (including hip dislocation) especially when swaddling with the hips and legs in extension and adduction (i.e. drawn toward the midline or sagittal plane of the body). Other risks associated with swaddling babies includes an increased risk of SIDS when a swaddled infant is placed prone (on his or her front) or able to turn to prone position. The SIDS risk seems to be increased by swaddling with the head covered. There is also a slightly increased risk of acute respiratory infections, which seems to be related to the tightness of swaddling. These are discussed in the systematic review of swaddling referred to above. Therefore, to swaddle properly and effectively, and to achieve the desired result, the blanket must be snug enough to immobilise the infant's arms, and to a certain degree its legs, but loose enough that it is still comfortable and not increase the risk of hip dysplasia or suppressed respiration. Many parents and carers experience difficulty with swaddling due to unfamiliarity with swaddling techniques. If not swaddled correctly, the infant often wriggles free of the swaddle thus becoming exposed to a risk of suffocation or SIDS-related issues due to loose bedding and unrestricted positioning of the infant. However, swaddling alone cannot eliminate these risks. This is especially true for infants that are more than around six weeks old, when they are stronger and more active than newborns. Even when swaddled tightly with all limbs securely enclosed, infants can potentially roll, becoming entrapped in the swaddling blanket or trapped face down while still wrapped in the blanket. To overcome the difficulty faced by parents and carers in learning proper swaddling techniques and to address the problems of improper swaddling, various swaddling suits have been developed. Swaddling suits such as the infant safety suit of WO 2007/098558 (the Snuggo), the Ergococcoon and the Woombi address the problems of wrapping too loosely or too tightly since the degree of wrapping is predetermined by the suit. As mentioned above, recent evidence shows that sucking on a pacifier is protective against SIDS. In addition, supplemental non-nutritive sucking (that is, sucking in addition to that required for feeding) is known to help to soothe an infant. Researchers have discovered that there is a clear reflex connection between the hand and mouth of a human fetus as early as 12-14 weeks after conception, and that thumb sucking in utero is common. After birth, many infants continue to soothe themselves by sucking on their thumbs or fingers. A newborn's ability to get the hands up to his or her mouth and suck is seen as a positive ability of the infant to organize him or herself in a self-soothing way. This helps establish an infant's ability to independently cope with stress and frustration. Thus it would be an advantage to have a swaddle suit that overcomes the problems of improper swaddling and also provides an opportunity for non-nutritive sucking. This would improve the calming effect of the swaddling suit, since research that indicates that multiple simultaneous measures such as swaddling and sucking (along with rocking, white noise and other interventions) have an additive calming effect on crying infants: Karp H, Swaddling and excessive crying, Journal of Pediatrics, July 2007, e2. None of the aforementioned swaddling suits facilitates non-nutritive sucking. None of WO 2007/098558 (the Snuggo), the Ergococcoon or the Woombi provide access to the hands while the infant is swaddled. Movement of the infant's arms in all three of these swaddling suits is restricted to 180 degrees below the shoulder line so the hands are restrained near the body but below the shoulder line, out of reach of the mouth. U.S. Pat. No. 7,587,769 is a swaddling article including a blanket formed with opposed arm-receiving sleeves that attempts to facilitate non-nutritive sucking by securing a pacifier to the blanket, thus overcoming the problem of pacifiers falling out of an infant's mouth. The blanket incorporates a pacifier retaining structure to retain a pacifier relative to the blanket so that the pacifier is unable to fall away from the blanket. This keeps the pacifier positioned near the mouth when the blanket is wrapped around an infant so it is available for the infant to suck on at will. The pacifier retaining structure includes a flap of fabric secured to the upper edge of the swaddling blanket. The flap is drawn across the region of the baby's mouth. A disadvantage of the swaddling article of U.S. Pat. No.7,587,769 is that it relies on a pacifier to be secured to the blanket. Another disadvantage is that it essentially extends the blanket across the face (around the mouth region), which can be uncomfortable and covering the face during sleep increases the risk of SIDs. Yet another disadvantage is that the swaddle article is in the form of a modified blanket and so lacks the convenience and advantages of a swaddling suit for example, the risk remains that the swaddle may loosen through movement thus becoming less effective and also posing a suffocation risk. While research indicates that there are benefits associated with non-nutritive sucking (e.g. pacifier use), it also indicates that pacifier use may be associated with problems including: interference with breast feeding, dependence on the pacifier (so the baby cannot sleep without one), an increased risk of middle ear infections, and dental problems associated with prolonged use. Hence, despite the established benefits of pacifier use, many parents choose not to use pacifiers. Further, some infants simply do not take to pacifiers. In any event, so as to minimise interference with breastfeeding, the recommendation is to wait until nursing is going well (usually one month) before offering a pacifier. Thus pacifier use is not suitable for all infants and it would be an advantage to provide a means for non-nutritive sucking that does not rely on pacifier use. Reflexes are set motor responses to specific sensory stimuli. Newborns have a hand-to-mouth reflex that is a natural instinct to get their hands to their mouths. Research indicates that this ability to access the hands for sucking is important for self-soothing. The hand-to-mouth reflex (along with the startle reflex) is one of a number of primitive reflexes present from birth or earlier. Primitive reflexes are thought to have provided evolutionary advantages to humans. The somatosensory system is a complex system of receptors and processing centres that produce the senses including touch, motion perception (proprioception) and balance, and spatial perception of body parts (kinesthesia). The tactile or skin senses (that rely on skin sensors for touch and pressure) appear first during fetal development. The vestibular system, which is responsible for movement and balance perception, and the tactile (touch) sensors are highly developed in newborns. The hand-to-mouth reflex goes with two reflexes that are considered essential to appropriate feeding responses in newborns: the rooting (or search) reflex and the sucking reflex. Both of these reflexes are triggered by a touch (including pressure) stimulus. The rooting reflex occurs when the infant's cheek or corner of the mouth is touched or stroked. The infant's mouth opens to follow and “root” (search) in the direction of stroking or touch. Rooting helps the baby to become ready to suck. The suckling reflex is triggered by touching the mucous membranes on the inside of the mouth with any object. Both reflexes facilitate nursing. In the hand-to-mouth reflex, when an infant's cheek is stroked, his or her mouth roots and the arm flexes. After hand and mouth find each other, the infant may suck energetically on the hands. There is a need for a swaddling suit that does not suffer the disadvantages of a swaddling using a blanket and that effectively swaddles infants by sufficiently restraining movement of the limbs to suppress the startle reflex, yet still affords sufficient movement so that infants can get their hand(s) toward their mouth, so providing the opportunity for non-nutritive sucking without reliance on a pacifier. U.S. Pat. No. 4,611,353 describes a swaddling garment in which an infant's arms are gently bound in a bent-elbow, hands-up position to inhibit the ability to fling open the arms without restricting arm movement. Binding of the arms in this manner is described as useful for holding a premature infant. The BabySense Cuddlewrap is a blanket shaped to wrap an infant's arms tightly near to the body and face, again as a means for suppressing jerks of the arms and legs. However, neither the manufacturer of the BabySense Cuddlewrap nor the inventor of garment of U.S. Pat. No. 4,611,353 refer to the benefit of providing access to the hands for non-nutritive sucking while swaddled and neither swaddle addresses this need adequately. While the swaddle of U.S. Pat. No. 4,611,353 is referred to as a garment, the part of the garment that is responsible for binding the arms in the manner described is two flaps of sufficient length to wrap around the infant and overlap each other, secured in place either by strips of hook and loop fasteners or simply by relying on the length of the flaps. Thus binding of the arms is achieved by a length of fabric in a manner analogous to a blanket. Loosening of the binding is possible with movement/wriggling of the baby—particularly in the embodiment that relies on the length of the flaps to secure the wrapping around the infant or where the hook and loop fastening is not sufficient to restrain loosening of the flaps through wriggling movement of the infant. Therefore, the risks associated with use of swaddling blankets or cloths remain with both the BabySense Cuddlewrap and the swaddle of U.S. Pat. No. 4,611,353, including: 1. wrapping too tightly so as to suppress respiration; 2. overwrapping the infant in several layers of fabric so as to increase the risk of overheating (particularly as the preferred embodiment of U.S. Pat. No. 4,611,353 also includes a hood); 3. loosening of the swaddle around the upper body will result in excess fabric around the upper body, posing a suffocation risk to the infant; 4. the arms are only restrained so long as the swaddle remains tightly secured around the infant and loosening allows increasing movement of the arms; 5. the swaddle does not facilitate or maintain access to the hands, although access can initially be provided depending on how the hands are positioned when the infant is first swaddled. Thus both U.S. Pat. No. 4,611,353 and the BabySense Cuddlewrap share many of the disadvantages of swaddling using a blanket, and do not act to secure the hands in position near the face to provide the opportunity for non-nutritive sucking without reliance on a pacifier. It is an object of the present invention to provide a new or alternative swaddling suit that swaddles infants by restraining movement of the limbs and which overcomes the disadvantages of other swaddling suits by allowing movement of the hand towards the mouth and maintaining the hand in a position relative to the infant's face thereby facilitating non-nutritive sucking.
Polarization-mode-dispersion (PMD) is a common phenomenon that occurs when light waves travel in optical media such as optical fiber and optical amplifiers. PMD occurs in an optical fiber as a result of small birefringence induced by deviations of the fiber's core from a perfectly cylindrical shape, asymmetric stresses or strains, and/or random external forces acting upon the fiber. PMD causes the two orthogonal polarization components of an optical signal corresponding to two principle states of polarization (PSP) of a transmission link to travel at different speeds and arrive at a receiver with a differential group delay (DGD). As a result, the waveform of optical signals may be significantly distorted, resulting in more frequent errors at the receiver. PMD is wavelength-dependent in that the amount or level of PMD imparted by an optical component (e.g., optical fiber) at a given time will generally vary for different wavelength-division-multiplexing (WDM) channels corresponding to different signal wavelengths or frequencies. Polarization-dependent loss (PDL) is another common phenomenon in optical fiber transmission. Optical components such optical add/drop modules (OADM's) tend to have PDL, which attenuate optical signals depending on the relative polarization state with respect to the PSP's of the PDL component. Polarization-dependent gain (PDG) is also a common phenomenon in optical fiber transmission. Optical components such as Erbium-doped fiber amplifiers (EDFAs), tend to have PDG, which amplify optical signals depending on their relative polarization state with respect to the PSPs of the PDG component. PDL and PDG cause signals to have different amplitudes at the receiver, which makes the optimal decision threshold different for different bits (depending on their polarization), and thus degrades the receiver performance when the receiver decision threshold can only be fixed to a certain level for all the bits. PDL may also cause varying optical signal-to-noise-ratio (OSNR) for bits with different polarization, and further degrade the system performance. PDL or PDG induced OSNR degradation cannot be compensated for since the process of adding random amplified spontaneous emission (ASE) noise cannot be undone. It is known that PMD, PDL, and PDG are significant penalty sources in high-speed (e.g., 10 Gb/s and 40 Gb/s) transmissions. PMD compensation (PMDC) is normally desirable to increase system tolerance to PMD. However, due to the stochastic nature of PMD and its wavelength dependence, PMDC is normally required to be implemented for each wavelength channel individually, and is thus generally not cost-effective. Various prior art methods have been proposed to achieve PMDC simultaneously for multiple WDM channels. Channel switching is one technique that has been proposed to mitigate the overall PMD penalty in a WDM system. However, such systems sacrifice system capacity due to the use of extra channels for PMD protection. Multi-channel PMDC before wavelength de-multiplexing has also been proposed to mitigate the PMD degradation in the WDM channel having the most severe PMD. However, such a mitigation scheme may cause degradation of other channels. Another scheme for a multi-channel shared PMDC has been proposed in which the most degraded channel is switched, by optical or electrical means, to a path connected to the shared PMDC; however, the speed of PMDC is limited (by the speed of the optical or electrical switching). In current PMDC schemes, PMD induced system outages, during which the PMD penalty exceeds its pre-allocated system margin and system failure occurs, are present, though reduced. Forward-error-correction (FEC) is an effective technique for increasing system margin cost-effectively. It has been determined, however, that FEC cannot extend the tolerable PMD for a fixed PMD penalty at a given average bit-error-rate (BER), even though the additional margin provided by FEC can be used to increase the PMD tolerance. It has been suggested that sufficient interleaving in FEC may increase PMD tolerance. However, there is no known practical method to provide the deep interleaving needed to avoid a PMD outage which may last minutes or longer in practical systems.
Hydrogen is an important feedstock in the manufacture of ammonia, methanol, and a variety of other chemicals; but its largest market is the crude oil processing industry. In crude oil refineries, hydrogen is used in a number of processes including hydrodesulfurization where hydrogen is reacted with sulfur containing compounds over a catalyst to form hydrogen sulfide. Hydrogen sulfide itself is already produced in great quantities during the drilling and processing of natural gas and oil. A process that can economically extract hydrogen from low value feedstocks or wastes such as hydrogen sulfide would bring tremendous benefits to the petroleum sector as this sector consumes large amounts of hydrogen. Many processes exist for the production of hydrogen. The production of hydrogen is currently dominated by the steam reforming process where a relatively light hydrocarbon is reacted with steam inside a bed of reforming catalyst, usually nickel. Since steam reforming of hydrocarbon is endothermic, the energy to drive the reactions must be provided from an external source. In the steam reforming process, the hydrocarbon-containing stream must be free of sulfur or other contaminants such as carbon particles that can poison and deactivate the catalyst. Another hydrogen production method is partial oxidation. In a partial oxidation reaction, a hydrogen-containing feed is reacted with an oxidizer, such as oxygen or air, in substoichiometric proportion normally referred to as a rich mixture where the equivalence ratio spans from one 1 to the upper flammability limit of the fuel being utilized as the feedstock. The equivalence ratio, defined as the stoichiometric oxidizer to fuel ratio divided by the actual oxidizer to fuel ratio, is shown in equation R1. EquivalenceRatio = ( fuel Oxidizer ) actual / ( fuel Oxidizer ) stoichimetry R1 An equivalence ratio less than unity is considered lean, also referred to as fuel-lean, since a portion of the oxidizer is leftover after all of the fuel is consumed by the oxidation reaction. Where the fuel content of the mixture lies below the lower flammability limit of the fuel used as the feedstock, the fuel and oxidizer mixture is considered ultra-lean. Conversely, fuel and oxidizer mixtures of equivalence ratio greater than unity are considered rich, also referred to as fuel-rich, since a portion of the fuel is leftover after the oxidation reaction is complete. Mixtures of equivalence ratios greater than rich mixtures, normally taken to be higher than the upper flammability limit of the fuel being utilized as the feedstock, are considered ultra-rich. Ultra-rich mixtures do not normally produce self-sustained flames without the aid of external energy sources or preheating the mixture. Although the partial oxidation process does not need an external source of heat since it is exothermic, it is still less common than steam reforming since it is generally less efficient than steam reforming particularly at large scale. As a normally non-catalytic process, partial oxidation can utilize any hydrocarbon feeds. The steam reforming and partial oxidation processes can be combined into a single process normally referred to as an autothermal process. In the autothermal process, the energy for the reforming reactions is provided by oxidizing a small portion of the fuel inside the bed of a reforming catalyst. Due to its catalytic nature, the autothermal process falls under the same constraints as the steam reforming process in that the catalyst bed is susceptible to poisoning and deactivation by sulfur, carbon, and other poisons in the feed stream. The hydrocarbon stream must be desulfurized in a first step prior to entering the autothermal reactor. During reforming, whether by the steam reforming or autothermal process, water must be provided in excess of the stoichiometric quantity to prevent carbon formation. Additionally, excessive temperature must be prevented in the reactions to avoid sintering the reforming catalyst. Steam reforming, partial oxidation, and the autothermal process are well known methods in the industry that are practiced on industrial scales. The invention disclosed herein can be an economical process for producing hydrogen from hydrocarbons and various other hydrogen containing fuels. U.S. Pat. No. 6,517,771 to Li, incorporated herein by reference, disclosed a reverse flow inert porous media reactor for the purpose of heat-treating metals. Li limited the reactant stream to methane and oxygen or air, and the preheater to initiate the process is located inside the porous bed. Drayton et. al 27th, International Symposium on Combustion, 27, pp. 1361-1367, 1998, incorporated herein by reference, disclosed an application of the reverse flow reactor for fuel reforming, producing synthetic gas from methane in a reactor similar to Li's. None of the disclosed references above include an external energy source for the reverse flow reactor or are applied to the reformation of hydrogen sulfide. A number of studies in reverse flow inert porous media reactors are carried out in applications not intended for hydrogen production from hydrocarbons. Hoffman et al, Combustion and Flame, 111, pp. 32-46, 1997, incorporated herein by reference, operated a reverse flow reactor with ultra-lean air and methane mixtures for the purpose of heating fluids. Barcellos et. al. Clean Air 2003, Seventh International Conference on Energy for a Clean Environment; Lisbon, Portugal, Jul. 7-10, 2003, incorporated herein by reference, tested a reactor similar to Hoffman's for the production of saturated steam through heat exchangers protruding directly through the inert porous media and fitted at the extremities of the reactor. Production of hydrogen from both light and heavy hydrocarbons as well as other hydrogen containing wastes such as hydrogen sulfide is not addressed in the prior art. Hydrogen is a much more valuable commodity then sulfur. A process that can economically recover the hydrogen as well as other compounds could have significant impact on the petroleum and other industries. The reformation of hydrogen sulfide (H2S) to hydrogen and sulfur presents certain challenges not encountered in hydrocarbon reformation. For example, the low heat content of H2S precludes obtaining very high temperature in the partial oxidation regime. More importantly, H2S reforming requires the reaction to reach near equilibrium conditions at high temperature to obtain high yield. In the current invention, the intrinsic heat recuperating mechanism of the inert porous media matrix and the reactor's ability to create an isothermal high temperature volume render it a cost effective option for the reformation of H2S and other hydrocarbons by providing the necessary residence time and temperature without the requirement of an external energy source to be used continuously throughout the reactions. Specifically, all of the reforming reactions in these above-mentioned prior art references occur inside a hollow chamber. None of these references disclose an apparatus and process where the reaction zone may be located in any portion of a reactor chamber, where the reaction zone is allowed to freely propagate through the reactor chamber filled with a porous media matrix and where the reforming reactions occur directly in a heated inert porous media matrix, or packed bed. Therefore, there has developed a need for a reactor which can efficiently reform both hydrocarbon and hydrogen sulfide fuels to pure hydrogen while not requiring continuous external energy to produce a viable hydrogen yield.
1. Field of the Invention The invention relates to a knuckle suited to be applied to a suspension unit for a vehicle such as a passenger car, a truck, a bus or the like. 2. Description of the Related Art As suspension units applied to vehicles, suspension units of an independent suspension type that independently support left wheels and right wheels with a view to improving the grounding property of the wheels have been employed. For example, suspension units of a multi-link type, a double wishbone type, and a McPherson strut type are well known. Especially a suspension unit of the McPherson strut type is constructed such that a knuckle for rotatably supporting each wheel is coupled to a vehicle body side via a lower arm, and that an intermediate part of this lower arm or the knuckle and the vehicle body side are coupled to each other by a shock absorber. The suspension unit of the McPherson strut type is therefore simple in structure and advantageous in space saving and cost reduction. A knuckle for use in a suspension unit that is made of an aluminum extrusion material as described in Japanese Patent Application Publication No. 8-324450 (JP-A-8-324450) has been proposed for the purpose of enhancing mass productivity and reducing manufacturing costs. However, in this knuckle described in Japanese Patent Application Publication No. 8-324450 (JP-A-8-324450), part of a bearing mounting body, an upper suspension arm mounting arm, and a lower suspension arm mounting arm are constructed as a first member made of an aluminum extrusion material, and the rest of the bearing mounting body and a tie rod mounting arm are constructed as a second member made of an aluminum extrusion material. The first member made of the aluminum extrusion material and the second member made of the aluminum extrusion material are so coupled as to be superimposed on each other in the direction of a central axis of a bearing. The knuckle is thereby constructed. In the knuckle thus constructed, especially in the former one of the members, that is, the first member made of the aluminum extrusion material, there is caused a problem in that the number of man-hours increases as a result of the need to cut the extruded extrusion material by means of water injection, laser beams, or the like, namely, the need to machine the extruded extrusion material.
Resistin gene polymorphisms and progression of glycaemia in southern Chinese: a 5-year prospective study. Human resistin gene (RETN) polymorphisms have been found to be associated with type 2 diabetes (T2DM), insulin resistance and/or obesity. We evaluated, in a 5-year prospective study, whether RETN polymorphisms could predict the progression of glycaemia in southern Chinese. We conducted a systematic search for variants in RETN in 70 southern Chinese subjects. This was followed by the genotyping in 624 unrelated nondiabetic subjects of two polymorphisms, -420C-->G and +62G-->A, previously reported in cross-sectional studies to be associated with T2DM in Asians, to examine their relationship with the progression of glycaemia in this cohort. We identified 15 polymorphisms, including 2 novel but rare polymorphisms (-319G-->A and +63G-->C). Compared to subjects with the CC genotype, -420GG subjects had higher 2-h glucose (7.7 +/- 1.8 vs. 7.2 +/- 2.0 mmol/l, P = 0.011) and insulin (101.6 +/- 69.5 vs. 79.8 +/- 59.5 mU/l, P = 0.021) during an oral glucose tolerance test. Carriers of the +62A allele had higher body mass indices (25.3 +/- 4.0 vs. 24.5 +/- 3.6 kg/m(2) in GG, P = 0.02). The presence of the allele -420G (OR 2.15, 95% CI 1.28-3.60, P = 0.004) or +62A (OR1.86, 95% CI 1.08-3.21, P = 0.025) predicted the progression of glycaemia at Year 5, after adjustment for sex, age or body mass index. The haplotype G-A also conferred a higher risk of progression in glycaemia (P = 0.002). Our study would support the role of the resistin gene in obesity, insulin resistance and progression of glycaemia in southern Chinese.
The present invention is directed to telecommunication networks, and especially to telecommunication networks involving calls from mobile calling instruments to special number service stations. An example of such a call from a mobile calling instrument to a special number service station is a call from a cellular phone, from a Voice over Internet Protocol (VoIP) calling instrument or from another wireless or otherwise mobile device to an emergency service station such as a Public Safety Answering Point (PSAP) in an emergency service call system. An emergency service call system, commonly known in the United States as an E9-1-1 System, will be employed herein as an exemplary preferred embodiment of the present invention. Other special number systems are deployed and would benefit from the present invention. Examples of such other special number systems include (by way of example and not by way of limitation) non-emergency police or fire call systems, telephone network maintenance call systems and commercially established special numbers (e.g., “dial ‘GOTIX’ on your AT&T Wireless phone for tickets”). A basic 9-1-1 (Emergency Services) System provides for programming with special 9-1-1 software a telephone company end office (also known as a “central office” or a “Class 5 office”) to route all 9-1-1 calls to a single destination. The single destination is termed a Public Safety Answering Point (PSAP). In such an arrangement, all telephones served by the central office would have their 9-1-1 calls completed to the PSAP. However, the areas served by respective telephone company central offices do not line up with the political jurisdictions that determine the boundaries for which PSAP may be responsible. That is, a municipal fire department or police department may geographically include an area outside the area served by the central office, a condition known as underlap. Likewise, the municipal fire or police department may encompass an area of responsibility that is less expansive than the area served by the central office, a situation known as overlap. Further, the original basic 9-1-1 systems did not provide any identification of the caller; the PSAP human operator had to obtain such information verbally over the line after the call was connected. The major shortcoming of the basic 9-1-1 systems was that they could not support interconnection to other telecommunication providers such as independent telephone service companies, Alternate Local Exchange Carriers (ALECs), or wireless carriers. The “basic” nature of the basic 9-1-1 system also indicates that the system does not have Automatic Location Information (ALI) capability or Automatic Number Identification (ANI) capability with a call back capability. Similar abbreviated number systems are in place for handling emergency service calls in countries other than the United States. The abbreviated number system established in Canada is the foreign system most similar to the system established in the United States. There are other abbreviated number calling systems in place in the United States and abroad for such purposes as handling municipal information and services calls (3-1-1) and for other purposes. All of these special or abbreviated number call systems that have geographic-based content suffer from similar shortcomings in their abilities to automatically place incoming calls to an action-response facility geographically proximate to the locus of the caller. It is for this reason that the 9-1-1 emergency call system of the United States is employed for purposes of this application as a preferred embodiment of the system and method of the present invention. Automatic Number Identification (ANI) is a feature for 9-1-1 services that allows the caller's telephone number to be delivered with the call and displayed at the PSAP. This ANI feature is sometimes referred to as Calling Party Number (CPN). The feature is useful for identifying the caller and, if the caller cannot communicate, for callback. A signaling scheme known as Centralized Automatic Message Accounting (CAMA), originally used to identify the originator of a long distance call for billing purposes, was adapted to facilitate ANI delivery to the PSAP. The availability of the caller's telephone number to the PSAP (the ANI feature) led quickly to providing the caller's name and address as well. This was straightforwardly accomplished using the subscriber information stored by telephone companies based upon telephone number since the 1980's. New equipment at the PSAP enabled queries of an Automatic Location Information (ALI) database using the caller's number provided by the ANI feature to ascertain name and address information. The ALI databases are typically maintained by the respective telephone company serving the PSAP. This was an improvement, but a problem still remained where several telephone company central offices served a town or county. Other problems also developed with the growing volume of mobile callers using wireless phones, satellite phones and communications over the Internet. Information regarding the locus of the origin of the call merely identified the locus where the call entered the wireline network; even such limited location information is not always provided. No indication was presented to identify the geographic location of such mobile callers. As the situation of multiple central offices serving a PSAP occurred more frequently, it was clear that it was inefficient to build communication trunks from several central offices to a PSAP. As a result the 9-1-1 Tandem was developed. With that equipment, trunks from central offices are concentrated at a tandem office (a 9-1-1 Tandem) from which a single trunk group serves a given PSAP. Often a 9-1-1 tandem comprises an otherwise common Class 5 telephone system end office (EO), with added software to configure it for 9-1-1 operations. Such concentration of trunks reduces size and cost of PSAP equipment. The tandem is a telephone company switch that provides an intermediate concentration and switching point. Tandems are used for many purposes, including intra-LATA (Local Access and Transport Area) toll calls, access to other local exchange carriers (LECs), and access to long distance carriers and telephone operators. A significant development in 9-1-1 services has been the introduction of Enhanced 9-1-1 (E9-1-1). Some of the features of E9-1-1 include Selective Routing, ANI, ALI, Selective Transfer and Fixed Transfer. Selective Transfer enables one-button transfer capability to Police, Fire and EMS (Emergency Medical Service) agencies appropriate for the caller's location listed on the ALI display. Fixed Transfer is analogous to speed dialing. Enhanced 9-1-1 services also permit provisioning supplemental data or information regarding calling parties, such as allergies to medications, presence of pets, infants or handicapped persons at the premises or similar information useful to responding to emergency service personnel. Selective Routing is a process by which 9-1-1 calls are delivered to a specific PSAP based upon the street address of the caller. Selective Routing Tandems do not directly use address information from the ALI database to execute decisions regarding which PSAP to connect. Recall that emergency services (Police, Fire and EMS) are typically delivered on a municipality basis. Often there will be one Police Department (e.g., municipal, county or state), but there may be several Fire Departments and EMS Agencies. The town will be divided into response areas served by each respective agency. The response areas are overlaid and may be defined as geographic zones served by one particular combination of Police, Fire and EMS agencies. Such zones are referred to as Emergency Service Zones (ESZ). Each ESZ contains the street addresses served by each type of responder. The ESZs are each assigned an identification number (usually 3–5 digits), known as Emergency Service Numbers (ESN). The Assignment of ESZs and corresponding ESNs enables the compilation of selective routing tables. The street addresses are derived from a Master Street Address Guide (MSAG), a database of street names and house number ranges within associated communities defining Emergency Service Zones (ESZs) and their associated Emergency Service Numbers (ESNs). This MSAG enables proper routing of 9-1-1 calls by the 9-1-1 Tandem; this is Selective Routing as implemented in an E9-1-1 system. Thus, the telephone company must have an MSAG valid address to be assigned the appropriate ESN for selective routing purposes and that information must be added to the E9-1-1 ALI database. It is by using such information that the selective routing capability of the Selective Routing Tandem can properly route an E9-1-1 call to the correct PSAP. If the information is not available in the ALI database, the record is placed into an error file for further manual handling. A portion of the ALI database may be loaded into a Selective Routing Data Base (SRDB) for use by the 9-1-1 Tandem. The SRDB may be located in the Tandem, in an adjunct processor, or in the ALI database. Reliability is a very important factor considered in designing 9-1-1 systems. One approach to providing reliability is to provide diversely routed trunk groups from each central office to its respective 9-1-1 Tandem. Preferably, each trunk group is large enough to carry the entire 9-1-1 traffic load for the respective central office. However, some systems are designed with less than full traffic capacity on trunk groups to “choke” or “congestion manage” incoming calls to a tandem in order to avoid overloading a PSAP. In some arrangements, parallel 9-1-1 Tandems are provided so that a central office has capable 9-1-1 Tandem ready for use (albeit with 50% call handling capacity) without interruption if one of the 9-1-1 Tandems fails. Switched bypass to an alternate 9-1-1 Tandem, commonly using digital crossover switches, is another approach to providing reliability in 9-1-1 systems. Another approach to providing redundancy and robustness for a 9-1-1 system is the employment of Instant Network Backup (INB). Using INB, if a call does not complete to the 9-1-1 network for any reason (e.g., trunk failure, facility problem, 9-1-1 Tandem failure or port failure), the INB takes over and completes the call to a predesignated 7- or 10-digit number. Using this INB alternate path, ANI and ALI information are not delivered, but the call is completed to a local public safety agency, usually the local PSAP. The interface between Operator handled calls and a 9-1-1 system is addressed in several ways. One system provides a direct connection between an Operator Tandem and the 9-1-1 Tandem. The operator forwards the call with the caller's ANI to the 9-1-1 Tandem. The 9-1-1 Tandem treats the call as though the caller had dialed the call. A second way to effect the desired interface is by using pseudo numbers. A pseudo number is a number that, when dialed, will reach a specific PSAP as a 9-1-1 call. Pseudo numbers have some special ALI information associated with them; for example, there may be a pseudo number associated with each municipality in a state. Dialing the pseudo number, usually from outside the LATA (Local Access and Transport Area), will generate a 9-1-1 to the PSAP for that municipality. The ALI display will indicate that it is a third party conference call from an unknown address in that town. The caller is not identified, but the call goes to the PSAP where the caller is believed, or claims, to be. Pseudo numbers are useful for Alternate Local Exchange Carrier (ALEC) or Competitive Local Exchange Carrier (CLEC) operators who may be located anywhere in the country. A third method for effecting an interface for operator handled calls with a 9-1-1 system is through the Public Switched Telephone Network (PSTN), dialing the directory number for the PSAP. This is often referred to as the “back door” number by ALEC and CLEC operators. The advent of wireless communications and other mobile phone capabilities (e.g., VoIP phones) has further exacerbated the difficulty of ascertaining caller location in telecommunication systems. The “patchwork” solutions described above regarding 9-1-1 systems have been mirrored in other special or abbreviated number systems to a significant extent. The “patchwork” solutions have created a capability-limited telecommunication system that cannot ascertain geographic information as fully or as easily as it should for all types of callers. This capability limitation has been especially felt in connection with calls made from mobile telephone instruments. The system is overly dependent upon human intervention to properly route calls to appropriate receivers, such as a proper PSAP. New modes of communication, such as Voice Over Internet Protocol (VoIP) and wireless communication instruments including wireless phones, wireless Personal Computers (PCs), wireless Personal Digital Assistant (PDA) devices and other mobile instruments, further contribute to telecommunication traffic not identifiable regarding geographic origin using present telecommunication routing systems. Similar limitations will likely occur in other abbreviated number, or other special number, telephone systems handling location-based calls with resulting adverse limitations. Other such abbreviated number systems include emergency call systems in countries other than the United States, abbreviated number calling systems for reaching telephone maintenance services, abbreviated number calling systems for municipal information and services, and similar systems. Provisioning of supplemental information to a special number service station (e.g., a PSAP in an emergency service call system) regarding a call originating from a mobile calling instrument is particularly difficult. Even with precise location information regarding locus of the origin of the call, such as would be available, for example, when the calling instrument has a Global Positioning System (GPS) capability, does not fulfill the need for availability of supplemental information regarding the calling party. Such supplemental information may include (by way of example and not by way of limitation) medical needs of the caller like allergies to medicines, or a request to notify specified personnel in the case of an emergency, or other information unique to the calling party that may be useful to responding emergency personnel. Other wireless systems, such as Automatic Collision Notification systems (ACN; one such system is referred to as ONSTAR™) may find it useful to alert responding emergency personnel that an infant or an invalid may be in an automobile involved in an accident. No systems are presently available to effect provisioning such supplemental information to a responding service station (e.g., a PSAP) for mobile instrument-originated calls. Mobile instrument-originated calls may include mobile telephone devices, wireless Personal Computers (PCs), wireless Personal Digital Assistant devices (PDAs), pager devices and other wireless-communication capable devices, whether capable of one-way or two-way communication. The present invention is also beneficial for other calling equipment having no particular fixed position, such as Voice over Internet Protocol phone devices (VoIP phones). There is a need for a system and method for providing particular information relating to a caller placing a call from a mobile calling instrument to a special number service station in a telecommunication network.
Assessment of lead exposure of children from K-XRF measurements of shed teeth. Lead is accumulated and immobilized for long periods of time in teeth. Thus the Pb concentration of a tooth can be used as an indicator of the cumulative Pb intake of a child. Shed and extracted teeth were collected from children in Beijing, China and some industrial regions in the Middle Urals in Russia. The Pb levels in the teeth were measured in Philadelphia, PA using an X-ray fluorescence (XRF) technique. Since Pb deposits in the tooth during the entire period that it is in the child, the measured tooth Pb level was divided by the age of the child when the tooth was shed and expressed in terms of (microgram/g-yr). 10% (n = 100) of the teeth from Beijing, China had Pb levels exceeding 5.5 and 3% above 9 micrograms/g-yr. For comparison, in the 1970s when urban environmental Pb levels were elevated, the tooth Pb levels in Philadelphia children were similar, i.e. 10% (n = 298) of the teeth had Pb levels exceeding 7.5 and 6% were above 9 micrograms/g-yr. Children in a more rural setting, Bennington, VT, had no detectable tooth Pb (n = 200). The Pb levels in the teeth from the Urals were much higher; 50% (n = 134) of the teeth had Pb levels exceeding 7.5 and 10% exceeding 17.8 micrograms/g-yr. The tooth Pb levels observed in the teeth from Beijing, and more so from the Urals, indicate that these children are residing in Pb polluted environments. Further studies are required to determine the extent of the Pb pollution and to explore the possibility that there are associated Pb-related health deficits.
Technological aspects as the main impact on quality of quince liquors. Phytochemical profiles of 24 quince liquors were studied as the combination of technologically variant. Liquors were obtained after macerating quinces from three varieties (Vranja, ALM3 and ZM2), with or without skin, at two ratios of quince:ethanol (50:50 and 25:75), and at two alcohol content (60% and 30%). Polyphenols were identified by LC-PDA-QTOF/MS and quantified by UPLC-PDA and UPLC-FL. A total of 18 polyphenolic compounds were identified and classified as 5 flavan-3-ols, 5 phenolic acids, and 8 flavonols. Flavan-3-ols were the most abundant group followed by hydroxycinnamates and flavonols. The highest contents of total polyphenols (∼1,000 mg/100mL) and antioxidant activity (37.1 mmol Trolox/100mL) were found in the liquors prepared using fruits with skin and 50:50 quince:ethanol ratio. The skin of quinces was the main source of phenolic acids and especially flavonols. The high antioxidant activity and polyphenolic content of quince liquor may be deemed as a promising new alcoholic beverage.
This invention relates generally to footwear, and more particularly pertains to a pocket formed within or appended to the gusset or tongue of a shoe, and having utility for temporary storage of personal items during shoe usage, as when employed during sporting events, jogging, or the like. One problem that repeatedly confronts the athlete, and particularly the modern sportsman who actively participates in golf, tennis, jogging, or the like, or even when partaking in various sports, such as hunting and fishing, is the ability to securely locate personal items in the category of tees, some loose change, money, and the like. Various means were earlier employed for assuring the safety of one's personal items, but particularly were designed for usage when some significant amounts of money were involved. For example, in the early United States patent to Diemer, U.S. Pat. No. 654,388, upon a shoe, means for securing valuable items concealingly within the calf portion of the shoe, and more specifically upon its internal portion that rest against the leg, was given consideration. Thus, the shown embodiment provided means for securing ones valuables such as money, and in addition to furnishing concealment of the same in the event that one was personally accosted, as by a theft. Various other forms of similar type pocket structures were used in association particularly with boots, as are also shown in the earlier United States patents to Wirsching, U.S. Pat. No. 1,289,341, McAuslin, U.S. Pat. No. 1,100,758, in addition to the patent to Avis, U.S. Pat. No. 1,342,149. More contemporary inventors have given thought to various types of structure for forming pocket structures within shoes and boots, and such is shown in the United States patent to Corley, U.S. Pat. No. 2,908,082. In addition, the concept of adding decorativeness to the shoe through the addition of a purse or the like, as by attaching the same upon the frontal shoe upper, is shown in the United States patent to Bliese, U.S. Pat. No. 3,018,570, but the additional structure to form the purse as shown in this patent was integrally constructed into the vamp of the shoe itself, and therefore, made it difficult to insert and keys, money, or the like therein, and furthermore, when such objects of some hardness were located therein, would certainly constantly maintain pressure upon the foot of the wearer. The United States patent to Solomon, U.S. Pat. No. 2,712,700, shows another means for adding some decoration to a shoe through the addition of a purse, or the like. Furthermore, the adding of a holding means having some utility to the shoe, as by securing the same through its laces to the shoe, is shown in the golf tee holder as devised by Perry in his U.S. Pat. No. 2,662,677. Similar type devices are currently available upon the market. All of the foregoing embodiments have utility for holding some component of personal item, such as money, in a concealed fashion upon its wearer, while the current invention, to the contrary, intends to provide a pocket portion that can be built structurally and foldably onto the gusset or tongue of the footwear, so as to hold smaller personal items such as keys and money, while further incorporating, in its construction, various means for assuring the retention of the pocket portion onto and contiguously with the shoe upper portion, at the location of its lacings, so as to prevent the untimely loss of such items. It is, therefore, the principal object of this invention to provide a pocket portion that is structurally built foldably onto the gusset or tongue portion of footwear, whether it be tennis shoes, jogging shoes, golf shoes, hunting shoes, work shoes, or standard dress shoes, and which incorporates closure means for the pocket portion so as to assure that personal items contained therein will not be inadvertently lost by the wearer. Another object of this invention is to provide a pocket portion that is integrally structured foldably connected onto the tongue portion of the shoe gusset, and which can assure the safety of items enclosed therein, while at the same time enhancing the attractiveness of the footwear. Another object of this invention is to provide fastening and securing means that snugly hold the pocket portion contiguously against the upper portion of the shoe particularly at the location of its lacing. A further object of this invention is to provide a footwear pocket, conveniently built appending onto the structure of the shoe, and which incorporates an opening or slot into which personal items may be quickly inserted, for safety and storage, but which items do not exert any pressure or bind onto the wearer's foot during footwear usage. Another object of this invention is to provide a shoe pocket integrally formed into the structure of the shoe and which can be conveniently and promptly installed during a stage of shoe assembly. A further object of this invention is to provide resilient means within the structure of a shoe or footwear pocket that enhances the formation of the said pocket portion and for its locating contiguously against the upper part of the said shoe. Still another object of this invention is to provide a pocket portion for a shoe and which contains supplemental strap means that may hold golf tees, or the like, to facilitate their usage. These and other objects will become more apparent to those skilled in the art upon reviewing the summary of this invention, and upon undertaking a study of the description of its preferred embodiment in view of the drawings.
A nine-year population-based cohort study on the risk of multiple sclerosis in patients with optic neuritis. Patients with optic neuritis (ON) are at an increased risk of developing multiple sclerosis (MS), an illness that may result in physical dysfunction and short life expectancy. Information on the conversion rate to MS of patients with ON is essential in determining the impact of ON on the incidence of MS. Previous Taiwanese studies on the risk of MS in patients with ON were all hospital based, thereby limiting the generalizability of the findings. We aimed to estimate the risk of MS in patients with ON using a nationally representative sample. A cohort of 2,741 patients who sought outpatient care for ON in 2000 was identified from Taiwan's National Health Insurance claims. The control group consisted of 27,330 age- and sex-matched subjects randomly selected from all beneficiaries in 2000. The person-year approach with Poisson assumption was used to estimate the incidence rate of MS from 2000 to 2008. The relative risk of outpatient visit or hospitalization for MS was estimated using the Cox proportional hazard model. The incidence rates of MS in the ON and control groups were 25.6 and 0.4, respectively, per 10,000 person-years; these values represent a relative risk estimate of 30.84 (95% confidence interval: 14.48 to 65.73) after the potential confounders were considered. Female or younger patients with ON were associated with a significantly elevated risk of developing MS. This study found that Taiwanese patients with ON are at a substantially high relative risk of developing MS. In addition to patients with ON, female and younger people should also receive intensive neurological care to further reduce their risk of developing MS.
Retrospective analysis of urologic complications in male patients with spinal cord injury managed with and without indwelling urinary catheters. To compare, in a retrospective fashion, the long-term urologic complications in male patients with spinal cord injury managed with and without indwelling urinary catheters. The records of 142 consecutive male patients with traumatic spinal cord injuries sustained between 1975 and 1985 (inclusive) were reviewed. Fifty-six patients were managed with indwelling urinary catheters, and 86 were managed without an indwelling catheter. Urinary complications were recorded for each patient under the following general subheadings: renal, urinary tract infection, stones, urethral, and other. In all, there were 95 complications in the noncatheterized group versus 202 in the catheterized group (P = 0.007). The catheterized group experienced significantly more problems with renal damage, recurrent urinary tract infection, stones, and urethral complications. Our study shows that elimination of indwelling urinary catheters in patients with spinal cord injury will significantly reduce the incidence of urinary tract complications and lead to better preservation of renal function.
The present disclosure generally relates to resins and resin blends and articles comprising thermoplastic polymers derived from 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimide monomers. Homopolycarbonate and Copolycarbonate resins derived from such monomers generally have a higher Tg and greater oxygen and water permeability than resins derived from the most widely available commercial polycarbonate, bisphenol A (“BPA”) polycarbonate homopolymers. As described herein, it is also possible to make such copolycarbonates with the transparency of polycarbonates and good color (i.e., low yellowness index) provided this monomer is made by a method that achieves sufficient purity. More particularly, the present disclosure relates to resin blends and articles comprising a polycarbonate comprising structural units derived from phenolphthalein derivatives, such as 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimide monomer and an ABS (acrylonitrile-butadiene-styrene) resin. The present disclosure further relates to resins and resin blends and articles comprising a polycarbonate comprising structural units derived from relatively pure 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimide. It would be desirable to develop a process for preparing relatively pure phenolphthalein derivatives such as 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimide, which can then in turn be used for producing polycarbonates and other polymers having significant content of structural units derived from this monomer, which polymers also have good color, (e.g., a yellowness index of less than about 10), and reasonably high weight average molecular weight (e.g., at least about 15,000). Further still, there is a need for such resins and resin blends and articles having excellent fire retardance and improved physical properties.
Another application for two degree of freedom manipulators is in the use of rehabilitation robots in order to provide support and/or assistive forces to a patient undergoing rehabilitation. Such manipulators are attached to a body part of the subject and can be used to provide assistive forces and support during a rehabilitation exercise such as gait training. For example, a 2DOF manipulator may be connected to a subject's pelvis to support their weight and provide predetermined gait cues to assist in walking One such manipulator is shown in US2007/0016116. In this document, a pair of pneumatically driven manipulators apply forces to the subject's pelvis with an arrangement of cylinders. In particular, fore-aft movement of the subject is provided by pneumatic cylinders mounted in the fore-aft direction, and lateral movement is provided by laterally orientated pneumatic cylinders. A problem with this arrangement is that the lateral cylinders mean that the manipulator is quite wide. This makes it more difficult to install, and the laterally extending pneumatic cylinders may clash with the subject's arms during normal gait motion. Also, the workspace is quite small compared to the size of the manipulator. A different, known, 2DOF manipulator comprises a 2D Cartesian slideway arrangement in which a carriage is slidable on a first rail in a first direction, which first rail is slideable between two further parallel rails in a second direction, perpendicular to the first. Such systems have certain disadvantages. One disadvantage is that there is a significant amount of equipment surrounding and within the workspace. This is generally undesirable in many applications, as the manipulator and the workpiece or subject may clash, and in the event that the manipulator is used for gait training, the rails may clash with the subject's arms. Another disadvantage with such systems is that sliding joints between components are generally undesirable because they are prone to contamination and wear. Also, in such a system a motor is provided to move the carriage on the first rail. The provision of a motor attached to the first rail, and arranged to move the carriage, means that the first rail has a high inertia, which is undesirable when being moved on the parallel rails.
Resource recovery operations on Earth require an economic feasibility with a financial return on the invested capital. The cost of transporting payloads to and from the moon is a barrier to economic development of the moon. Rocket propelled space vehicles transporting cargo outside the proximity of the Earth in airless space do not require the same vehicle hardware to push up through the atmosphere or land on the moon, but discarding the vehicle hardware on each mission like Apollo is still expensive. The space exploration initiative announced by President Bush and implemented by NASA has the opportunity to mature the transportation cycles beyond the Earth and the moon. The requirements and cost for each of these six lunar transportation cycles is different and the requirements for manned versus unmanned missions differs greatly. If one breaks out these different cycle or leg transportation requirements for each portion of a lunar trip, then six distinct transportation cycles emerge. As each cycle matures, it becomes more effective and efficient Commerce competitive forces help accelerate this maturing process and the evolution into a cost competitive transportation environment. The transportation cycles emerging are Earth to low Earth orbit or LEO, LEO to Lunar orbit “LO,” LO to the lunar surface, the lunar surface back to LO, LO to LEO and the re-entry from LEO to the Earth's surface. Placing a transportation node between each of the separate cycles would accelerate the maturing of the transportation process and facilitate introducing commerce. In a mature transportation cycles on Earth, we find that changing the requirements for a portion of a trip, like from water to land results in the change of a vehicle and results in a harbor emerging. Why not fly and eliminate the harbor? Well, people fly, eliminate the harbor and pay the extra cost, but most cargo goes a different less expensive route through the harbor. The airport becomes the transportation node for humans and the harbor is for cargo with very different costs related to transportation. Aircraft manufacturers want all humans and cargo to fly, but when paying for the transportation, the cost competitive aspects become important. In a remote site like the moon, the ratio of humans to cargo is significantly skewed. In looking at similar remote locations on Earth the ratio is less than 1% human and 99% cargo. To combine the manned and unmanned portions as we did in Apollo makes space transportation expensive, in part, because the safety and reliability of manned space flight is expensive. Such manned vehicles may be similar to the Saturn vehicle of the Apollo project, which landed the first man on the moon more than 30 years ago. The next series of exploration trips to the moon might consider separating unmanned cargo from humans in some manner consistent with safety. Rendezvousing, docking and transferring payloads between space vehicles was performed more than forty years ago in the Apollo program, and more recently between shuttles and the International Space Station. The Apollo program used a form of transportation node, for example, the astronauts had to transfer cargo from the lunar lander to the command module in lunar orbit. The command module in lunar orbit was a node in the transportation system and saved mass from being transported to and from the moon's surface. Today these transportation node techniques and procedures can be refined and used, for example, between each of the six transportation cycles and two of the nodes already exist, the Spaceports on Earth and the International Space Station. Travel between them has become partly commercial and will become competitive. In such conventional systems, the actual transfer of cargo is performed by people after docking of the vehicles and opening of a hatch, However, the automatic transfer of cargo between two vehicles in space, such as unmanned space vehicles, is a more complex operation, but possible by combining innovation with conventional systems. The enhancement of the transportation process to be more effective and more affordable can also happen. U.S. Patent Application Publication No. 2002/0079407 to Lounge et al. entitled, “Underway replenishment system for space vehicles” discloses a replenishment system used to deliver payloads and supplies to an orbiting receiving space vehicle using a tether. The 2002/0079407 application does not enhance the payload movement. The 2002/0079407 application discloses a method of transferring payloads between a delivering space vehicle and a receiving space vehicle, but falls short of a transportation node. U.S. Pat. No. 4,790,499, to Taylor, et at, describes docking with an orbital object using a tether. Docking with an object at the end of a cable is less likely to damage the orbital facility because both objects can move in rendezvous and docking operations. The '499 patent discloses a passive operations with no mention of active “seeker” tether tip operations.
Providing a query to a search engine on a network, such as the Internet, often results in large numbers of search results being returned to the user, each reference presumably having information determined to be relevant to the search query. Unfortunately, there is no easy way for a user receiving such search results to know what is really of interest to him/her without reviewing the informational content of most, if not all, the search results returned to him/her. However, such a review is at least burdensome if not physically impossible in cases where an extremely large number of search results (e.g., 2,000 to 100,000 or more) are provided to the user. Accordingly, the user has the option of spending a substantial amount of time reviewing the search results, and/or reviewing only portions of the search results and hoping that the information he/she desires occurs in the search results reviewed. Accordingly, it would be desirable to have a capability for the user to obtain such search results in an order that puts the results of more likely interest or importance to the user toward the front/top of the list of returned search results, and/or puts the results of less likely interest or importance to the user toward the end of the list of returned search results. More particularly, it would be desirable to use information indicative of past user interests (and/or the interests of other users “similar” to the user) to order the user's subsequent search results so that the results more likely to be of interest to the user are presented first.
"[twig snapping]" " I got a bad feeling, mama." ""you be careful, boy." "Don't get yourself hurt none."" "Don't worry your pretty little head, mama." "Ain't nothing gonna happen to the finger." ""don't get cocky." ""you know he's out there." "He's watching you."" "Don't nag me, mama!" "I ain't no little kid no more!" "[bushes rustling]" "[sighs]" " [roars]" " ♪ teenage mutant ninja turtles ♪" "♪ teenage mutant ninja turtles ♪" "♪ teenage mutant ninja turtles ♪" "♪ heroes in a half shell, turtle power ♪" " ♪ here we go, it's a lean, green, ninja team ♪" "♪ on the scene, cool teens doing ninja things ♪" "♪ so extreme, out the sewer like laser beams ♪" "♪ get rocked with the shell-shocked pizza kings ♪" "♪ can't stop these radical dudes ♪" "♪ the secret of the ooze, made the chosen few ♪" "♪ emerge from the shadows to make their move ♪" "♪ the good guys win, and the bad guys lose ♪" "♪ ♪" "♪ leonardo's the leader in blue ♪" "♪ does anything it takes to get his ninjas through ♪" "♪ donatello is the fellow who has a way with machines ♪" "♪ raphael's got the most attitude on the team ♪" "♪ michelangelo, he's one of a kind ♪" "♪ and you know just where to find him when it's party time ♪" "♪ master splinter taught 'em every single skill they need ♪" "♪ to be one lean, mean, green, incredible team ♪" " ♪ teenage mutant ninja turtles ♪" "♪ teenage mutant ninja turtles ♪" "♪ teenage mutant ninja turtles ♪" "♪ heroes in a half shell, turtle power ♪" " There." "[music box plays melody]" " Too much?" " Do you really want my opinion?" " Only if you think it's perfect." " It's perfect!" " Wow, that is just super neat." "Thanks so much, donnie!" "[music box closes] well, got to go!" "Got some, uh, training to do... [chuckles] thanks again, donnie!" "[door opens, closes]" " I can't even imagine how you're feeling right now." " Devastated." " Aw, man!" "I was totally gonna say "devastated"!" "I should've just went for it." "I got to learn to trust my instincts!" "I mean..." "That's rough, bro." " [groans]" " Smooth move, genius." "It's never gonna happen, donnie." "We're mutants." "She's a girl." "You're a giant talking turtle." "The sooner you get used to it, the better." "You know what you need?" "Huh?" "Huh, buddy?" "You know what you need?" " You to leave?" " A little forest ninja training!" "Ha!" "Huh?" "Huh?" "Sounds like fun, right?" "Right?" " [whimpers]" " [grunting]" "Aw, you guys are rustier than the titanic's butt!" " No, we're" " You're not in the city anymore." "You need to get used to this new environment" "No buildings, no subways." " Lots of trees." " Ugh, tell me about it." " Well, what do you think?" " Hmm..." "Turtle hunt." " Turtle hunt." "Both:" "Turtle hunt?" " You gonna help out, leo?" " Yeah, I-- [groans]" "Sorry." "I guess I'm still not up to it." "Enjoy your little hunt, guys." " Dude!" " What do you mean by "turtle hunt"?" " You guys are gonna head into the forest." "I'll give you a five-minute head start," "Then I hunt you down." "If you can't stay hidden for at least an hour," "You'll have to..." "Clean out the chicken coop." " No way!" " Not the chicken coop, man!" " It smells like cheese fossils!" " It's got spiders so big, they play the banjo!" "[banjo music plays]" " We can't clean that thing!" " Then get moving." "[both yell]" " How do we hide in the woods, anyway?" "There's no doors!" " Hmm." "Ah!" "We could climb a tree." " That's the first place he's gonna look." "Could we burrow?" "Do turtles burrow in the wild?" " I don't know." "I've never been in the wild before." "Have you?" " Does jersey count?" "[distant roaring]" "What the heck was that?" " It's got to be raph messing with us!" "Right?" " We got to hide, now!" " Aw, we are so cleaning that coop." "Raph's gonna find us up here in, like, five seconds." " I don't think so." " Why not?" " [growling]" " Um..." "Hi?" "[both screaming]" " [roaring]" " What is it?" "Some kind of monkey man?" " It looks like the mythical sasquatch..." "Bigfoot!" "[both grunt]" "He's too big." "Run!" " [screaming]" " Come on, you're not even trying to hide!" "Both:" "Bigfoot!" " Yeah, right." "If you think you're gonna get out of cleaning that coop by-- [all screaming]" "Looks like we're gonna get some real training." " [roaring]" " Booyakasha!" "[yelling]" " Bigfoot got some skills." " Wah!" " [crying]" " Hey, are you" " Stop!" "Guys, he's hurt!" "I don't think he wants to fight us." "I think he's just scared." " Scared." " He can talk?" " Look at that sagittal crest." "It could be a paranthropus robustus," "A hominid long thought extinct!" " [muffled] can't breathe!" " Okay, okay, easy now..." "Easy." "I can fix your arm if you let me." "It's okay." "I want to help." "It's not bad, but I'd like to take you home" "Where we can clean it up and bandage it." "Is that okay?" " Hello?" "Anybody?" " No way!" "We can't bring a giant ape-man home with us!" " Of course we can." "Mikey?" " Injured woodland creature?" "Bring him home." " Two to one, raph." "Sorry." "Hi." "I'm donnie." "This is raph, and this is mikey." " I." " I?" "Okay, your name is I?" " I..." "No name." " Of course you have a name." "You're bigfoot!" " Bigfoot!" "[laughs]" "Bigfoot." " Will you come with us?" " [whimpers]" " It's okay." "You're gonna be safe with us." " Why would he be scared of us?" " Well, mama..." "Been hunting this hairy freak for years now." ""and now he goes and finds hisself some more freaks!"" "Settle down, mama." "Ain't no little green aliens" "Gonna save bigfoot from the finger." " Hello?" "Anybody home?" "We got company!" " What?" "You can't let anyone in." " Why is the doorway full of hair?" " And a giant butt?" "Come on, it's okay." " [gasps] - it's bigfoot!" " You brought bigfoot home?" " Why everyone know bigfoot name?" " Bigfoot, this is leo, casey, and April." " He's hurt!" "I'll get the first-aid kit." " You can't just bring home bigfoot!" " [chuckles awkwardly]" " He needs our help..." "Just until his arm gets better." " Come on, let's get that wound cleaned up." " Sure, but when I wanted to have a dog," "You guys were like like, "no way."" " You guys don't get it." "Bigfoot is the missing genetic link" "Between humans and the ape." "This discovery will change the face of science itself." " So it's bigger than talking turtles?" " [growls]" " There you go." "Try not to use it too much for the next few days." " Mm-hmm." "Bigfoot thank donnie." " No problem." " Bad man after bigfoot." "Name--the finger." " The finger?" " Very bad mans." "But donnie good mans." " Aw, thanks, bigfoot." " Donnie very good mans..." "So good." "Bigfoot..." " Whoa." " Ah!" " Love donnie!" " But, but, but" " Bigfoot am lady!" " That..." "Is..." "Great?" " That..." "Is great!" "[laughter]" " Bigfoot bring meat!" " Where did you" " Good meat." "[laughs]" "Tender, tender." " [screams, retches]" " Bigfoot make waste." " Uh, make waste?" "[foghorn blares]" "Aah!" "Bigfoot!" "Donnie and mikey need to learn to blend in out here" "Forest stealth." "If you're gonna stay with us, at least you can help out." "So show them some stuff, okay?" "I have to go clean out the tub." "[breathing deeply through mask]" " Please don't grab my head again." " Blend in." " I can still see him." " Mama, looks like bigfoot got him a couple" "Of little green alien buddies." "The finger is okay with that." "[weapon clicks]" " Huh?" "[gasps] [both screaming]" " What are you" " Ugh, you're squishing me!" " Darn it!" "Lost 'em, but not for long." " Come on, leo, give me your best!" " You'll gain no ground." " Oh, man, bigfoot is amaze-balls" "With the forest-stealth stuff!" " Bigfoot scared." " Aw." " Finger bad!" " Right, fingers are bad." "Hey, donnie, want to play the winner?" " Evening, bigfoot." "What are you making?" " Food!" " Aah!" " Donnie!" " Um, you realize..." "That meat has fur?" " Mm-hmm." "Hmm?" "[cat screeching]" " [screaming]" " [screeching]" " [screaming]" " [screeching]" " [screaming] - [screeching] [meows weakly]" " Bigfoot..." "Need..." "Help." " Sure, what bigfoot wa" "I mean, what do you want?" " Makeover." "Huh?" " Okay, and a little off the top here." "[humming]" "Well?" "Uh..." "[laughs]" "So what do you think?" " Eat!" " Gah!" "Did you..." "Wow--whoa." "Uh, yeah, um, uh..." "Thank you." "Got to go, bye!" " [whimpers]" " Ugh." "This is so uncomfortable." "Bigfoot follows me around everywhere" "Like a love-struck puppy." " Now you know how April feels." " [whimpers] [distant laughter]" " So she's wearing makeup now," "And she keeps making soup for donnie." " Do you think she's his type?" " Maybe after a shave!" "[both laughing]" " [whimpering]" " Bigfoot, wait!" " [crying]" " What is wrong with you guys?" " We didn't mean to hurt her feelings." " Bigfoot!" "Wait up!" " [crying]" " Mama, your boy's got 'em right where he wants 'em." ""iffen you play your cards right," "Maybe you'll get your own alien-hunting reality show!"" "Ooh, just like cousin fatback!" "Ohhhhh, doggie!" " [crying]" "[whimpering]" " How many years the finger been chasing you?" "Well, guess what." "Mama says the chasing's over." "Bigfoot, you gonna make mama and the finger rich!" ""I'm so proud of you, the finger."" "Aw, shucks, mama..." " What the" "Huh?" "[thud]" " Puppies..." "Too many puppies..." "Aah!" " Donnie, I just had the worst dream about" " I'm not sympathetic right now, mikey." "The finger has been debating whether to pickle us" "Or stuff us." " Ooh, pickle!" "Pickles taste so good!" " [sighs]" " Ain't got no room for these two on the cart, mama." "Looks like the finger's gonna have to stuff 'em right here." " I've got an idea." "Follow my lead." "Hey, finger!" "Your mama looks like a raisin!" " "what'd he say about me, the finger?"" " Uh..." "Your mama's so wrinkly, she looks like" "One of those little dogs..." "With all the wrinkles." " A shar-pei?" " Your mama's" "Uh, your mama's a shrunken head!" " Shut up!" ""destroy them."" " Bad move, the finger." " The finger got skills!" " Wah!" " [groans]" "Ha!" "Forest stealth!" " [growling]" "Oh, yeah!" "Oh, yeah!" "Oh, yeah, brother!" "Oh, yeah!" "Ha!" " [gasps] [classical music]" "♪ ♪" "This is gonna hurt!" "[groans]" " You can't beat the finger!" "He's too strong for you!" " Hey, finger!" " How many more explosive bolts you got in that quiver?" " 42." "[groaning]" "If the finger's going down, he's taking bigfoot with him!" "Bigfoot" "Bigfoot's a lady?" "The finger can't shoot no lady!" "The finger's sorry, mama!" "He didn't know!" "He would never hurt no lady!" "[crying]" " There, there..." "It am be okay." "Huh?" "[heart beating rapidly]" " [crying]" " Bigfoot take care sad mans." " [grunting]" " Hey, April." " What's up, donnie?" " I, um..." "Well, I just wanted to let you know" "I won't be bothering you with music boxes anymore." "I get it now." "Donnie is to April as bigfoot was to donnie." "I'm just..." "A mutant." " You're not just a mutant, donnie." "You're my mutant." "Mwah." " I understand nothing."
A widely used method for affixing toner materials to a receiver sheet is by the application of high temperature and pressure in the fusing subsystem of a photocopying machine. A common configuration for a fusing subsystem is to place a pair of cylindrical rollers in contact. The roller that contacts the side of the receiver sheet carrying the unfixed or unfused toner is known as the fuser roller. The other roller is known as the pressure roller. The area of contact is known as the nip. A toner receiver sheet containing the unfixed or unfused toner is passed through the nip. A soft coating on one or both of the rollers allows the nip to increase in size relative to the nip which would have been formed between two hard rollers and allows the nip to conform to the receiver sheet, improving the fusing quality. Typically, one or both of the rollers are heated, either through application of heat from the interior of the roller or through external heating. A load is applied to one or both rollers in order to generate the higher pressures that are necessary for good fixing or fusing of the toner to the receiver sheet. The application of high temperature and pressure as the receiver sheet passes through the nip causes the toner material to flow to some degree, increasing its contact area with the receiver sheet. If the cohesive strength of the toner and the adhesion of the toner to the receiver sheet is greater than the adhesion strength of the toner to the fuser roller, complete fusing occurs. However, in certain cases, the cohesive strength of the toner or the adhesion strength of the toner to the receiver is less than that of the toner to the fuser roller. When this occurs, some toner will remain on the roller surface after the receiver sheet has passed through the nip, giving rise to a phenomenon known as offset. Offset can also occur on the pressure roller. Offset is undesirable because it can result in transfer of the toner to non-image areas of succeeding copies and can lead to more rapid contamination of all machine parts in contact with the fusing rollers and to increased machine maintenance requirements. It can also lead to receiver (e.g. paper) jams as the toner-roller adhesion causes the receiver sheet to follow the surface of the roller rather than being released to the post-nip paper path. It is common in some machines to apply release oil externally to the roller in the machine as it is being used. The release oil is typically poly(dialkylsiloxane) (PDMS) oil. PDMS oil does an excellent job in its role as release agent; however, there are associated disadvantages. The release agent's compatibility with PDMS-based roller materials result in swelling of the rollers. This swelling cannot be easily compensated for, since it is generally non-uniform. Paper passing over the rollers can wick away some of the release oil within the paper path, resulting in a differential availability of the release oil to roller areas within and outside the paper path. This causes differential swell of the roller inside and outside the paper path so that a "step pattern" is formed in the roller. This can cause problems when different size papers are used and can lead to increased wear and decreased roller life as described in U.S. Pat. No. 5,753,361. This wear can also lead to an uneven pressure distribution between the two rollers of the fusing assembly resulting in poor print quality as described in U.S. Pat. No. 5,035,950 and as is well known in the art. Another associated problem is the tendency of a silicone layer to soften as it swells with the polydimethylsiloxane release fluids and its subsequent debonding as described in U.S. Pat. No. 5,166,031. Here the suggested solution to the problems of the silicone fuser member coating was to develop fluoroelastomer analogs to replace the silicone. However, the toner's tendency to offset is sacrificed. In applications using a donor roller oiling system, the use of a silicone based outer layer and its subsequent swell by the polydimethylsiloxane release fluid results in excessive swelling leading to failure of the roller to provide a uniform layer of release fluid as described in U.S. Pat. No. 4,659,621. Here the suggested solution to the problems of the silicone fuser member coating was to develop fluoroelastomer analogs to replace the silicone. However, the toner's tendency to offset is sacrificed. There continues to be a need for improved fuser and pressure rollers with improved fusing performance, e.g., reduced impact of swell on wear resistance without reducing the toner releasability as well as improved mechanical properties and thermal conductivity.
The invention concerns a method for automatically controlling the pressure of a common rail system on an A side and a common rail system on a B side of a V-type internal combustion engine. V-type internal combustion engines have a rail on the A side and on the B side for temporary storage of the fuel. The injectors, which are connected to the rails, inject the fuel into the combustion chambers. In a first design of the common rail system, a high-pressure pump pumps the fuel into both rails at the same time, which is accompanied by an increase in pressure. Therefore, the same rail pressure prevails in both rails. A second design of the common rail system differs from the first in that a first high-pressure pump pumps the fuel into a first rail, and a second high-pressure pump pumps the fuel into a second rail. Both designs are described, for example, by DE 43 35 171 C1. Since the quality of the combustion is critically dependent on the pressure level in the rails the pressure level is automatically controlled. Typically, a closed-loop pressure control system comprises a pressure controller, the suction throttle with high-pressure pump, the rail as the controlled system, and a filter in the feedback path. In this closed-loop pressure control system, the pressure level in the rail is the controlled variable. The measured raw values of the rail pressure are converted by the filter to an actual rail pressure, which is compared with a set rail pressure. The resulting control deviation is then converted by the pressure controller to a control signal for the suction throttle. The control signal corresponds to a volume flow in units of liters/minute, which is implemented electrically as a PWM (pulse-width-modulated) signal. A corresponding closed-loop pressure control system is known from DE 10 2006 049 266 B3. An internal combustion engine provided as a generator drive is operated to realize a constant 50 Hz mains frequency in a closed-loop speed control system. The raw values of the controlled variable, i.e., the speed of revolution, are detected on the crankshaft, filtered, and compared as the actual speed with a reference input, the set speed. The resulting control deviation is then converted by a speed controller to the correcting variable, a set injection quantity. A load reduction is a process that is difficult to control in an internal combustion engine with closed-loop pressure control and closed-loop speed control, first, due to its dynamics and, second, due to the different step response times of the two closed-loop control systems. Previously known measures for improving the response time in a load reduction, are regulation of injection start (DE 199 37 139 C1), switching to a faster speed filter (DE 10 253 739 B3) or pressure filter (DE 10 2004 023 365 A1), or temporarily increasing the PWM signal. In addition, DE 101 12 702 A1 discloses that in the case of large changes in dynamics, the response time of the closed-loop pressure control system can be improved by an input control variable. The high-pressure pump is controlled by the input control variable. The input control variable is computed from the set fuel quantity, the speed of the high-pressure pump, and the rail pressure. A common feature of the methods described above is their use with a closed-loop pressure control system in a common rail system of the first design.
High incidence of nephrocalcinosis in extremely preterm infants treated with dexamethasone. The use of postnatal corticosteroids to treat or prevent chronic lung disease is common in very preterm infants. Medullary nephrocalcinosis has been noted as a possible side effect. This prospective study was designed to assess the incidence of nephrocalcinosis in extremely preterm infants exposed to dexamethasone. A prospective study of extremely preterm infants, recruited to a randomized trial of dexamethasone treatment for chronic lung disease, was initiated. Infants had US of the renal tract scheduled on entry into the study, at day 28 and at discharge or at the corrected gestational age of 36 weeks. Thirty-three infants were enrolled in the study. Birth weight ranged between 440 and 990 g and gestation between 24 and 28 weeks. Nine infants died and six had incomplete data. Because there was no difference in incidence of calcification between those on the short course and those on the long course of dexamethasone, analysis was made on the entire cohort. One infant had nephrocalcinosis at the time of the initial US examination on day 26 of life. By day 28, nephrocalcinosis was present in 31% of those with complete data. By discharge, or corrected gestational age of 36 weeks, US evidence of nephrocalcinosis was present in 15 (83%) of 18 infants. All infants had at least one course of an aminoglycoside antibiotic during the study. All infants had parenteral nutrition. Only four infants received furosemide more regularly than single doses. The longest course was 10 days, received by an infant who did not develop nephrocalcinosis. The incidence of nephrocalcinosis is high in this group of sick, extremely preterm infants. Dexamethasone may be a factor in the development of nephrocalcinosis. Future research should focus on the natural history of nephrocalcinosis in extremely preterm infants.
An exploration of the way in which the concept of patient advocacy is perceived by registered nurses working in an acute care hospital. The purpose of this study was to provide a beginning exploration of the way in which registered general nurses perceived the concept of patient advocacy. A qualitative approach was taken using the techniques of the grounded theory method. A volunteer sample of eight registered nurses working in an adult acute care ward of a major metropolitan hospital were interviewed using an semi-structured format. Areas explored during the interviews included personal definitions of patient advocacy, elements of the advocate role, and the rationale for the nurse acting as patient advocate. Data analysis commenced during the data collection phase, where initial interviews were transcribed, coded and beginning categories were identified. The findings indicate that for the participants, advocacy is based on respect for the person, and acknowledgement of human rights. The quality of the relationship between the nurse and the patient appears to be the basis for the advocate role. Three initial categories emerged that describe the major elements of the participant's conceptualization of patient advocacy. These are, informing, supporting and representing.
Detailed Investigation of the OH Radical Quenching by Natural Antioxidant Caffeic Acid Studied by Quantum Mechanical Models. The effectiveness of naturally occurring antioxidant caffeic acid in the inactivation of the very damaging hydroxyl radical has been theoretically investigated by means of hybrid density functional theory. Three possible pathways by which caffeic acid may inactivate free radicals were analyzed: hydrogen abstraction from all available hydrogen atoms, hydroxyl radical addition to all carbon atoms in the molecule, and single electron transfer. The reaction paths were traced independently, and the respective thermal rate constants were calculated using variational transition-state theory including the contribution of tunneling. The more reactive sites in caffeic acid are the C4OH phenolic group and the C4 carbon atom, for the hydrogen abstraction and radical addition, respectively. The single electron transfer process seems to be thermodynamically unfavored, in both polar and nonpolar media. Both hydrogen abstraction and radical addition are very feasible, with a slight preference for the latter, with a rate constant of 7.29 × 10(10) M(-1) s(-1) at 300 K. Tunnel effects are found to be quite unimportant in both cases. Results indicate caffeic acid as a potent natural antioxidant in trapping and scavenging hydroxyl radicals.
A. Technical Field The present subject matter is directed to items that are usable to help educate children in learning activities. More specifically, the present subject matter is directed to the field of educational devices for teaching people about wave action and the dynamics of liquids. B. Description of Related Art Duck races are a popular pastime. It is not uncommon to see hundreds or thousands of people converge on a river to put ducks, which are almost universally yellow, into a river to see whose duck reaches the finish line first. Often, there is an entry fee and the proceeds may go to the winner or be given to a charity. It is fun for all, but the outcome is determined solely by luck. It is an object of the present subject matter to provide a water raceway device designed for racing ducks or other floating objects, where skill is a factor in the outcome of the race. It is a further object of the present subject matter to provide a water raceway device where the floating objects are conveyed down a first sluice primarily by the action of waves and are conveyed down a second sluice primarily under the force of currents. It is a further object of the present subject matter to provide an insert that can be positioned in a tub to convert the tub into a device for racing floating objects. It is a further object of the present subject matter to provide an educational experience that is so much fun that participants may not realize that they are learning about fluid dynamics and currents and waves. It remains desirable to provide improvements in water raceway devices
Shipping of vegetable and ornamental plants generally, and more particularly, smaller, fragile plants and seedlings that have yet to reach maturity, has always posed certain challenges for growers, distributors and retailers. Sustaining the plants in a viable condition and protecting them from handling damage very often have been primary concerns. Over time, methods of buying, selling and delivering plants have undergone significant change. Early on, plants were made available and purchased on a carry-out basis at a local nursery. Later, plants became available through more indirect means such as grocery, hardware and discount stores, as well as through various other middleman outlets. More recently, purchasing via mail and telephone order from direct mail catalogs distributed by non-local vendors has become increasingly prevalent. Plants and seedlings ordered from such catalogs typically are delivered to the customer through the mail or other similar means. The advent of long distance shipping of plants through the mail and other means has resulted in the creation of a variety of containers designed to maintain and guard plants during shipment. Some examples of containers created with such purposes in mind can be found in U.S. Pat. Nos. 5,613,605; 4,471,573; 3,342,329; 3,021,046 and 2,736,138. U.S. Pat. No. 5,613,605 discloses a plant package for use in self-service retail sales stores, as well as other sales methods such as mail order. The package is a self supporting, light transmissive polymer shell formed by two separate elements that snap together to fully enclose a single plant. U.S. Pat. No. 4,471,573 discloses a folding package for up to three plant pots filled with soil and plants, bulbs or tubers. The package is used for the transport and display of the plant item in shops and consists of an assembly of three blocks of triangular shape that when folded together enclose the pot and stem region of the plant items contained therein. The package preferably is manufactured from a transparent plastic material. U.S. Pat. No. 3,342,329 discloses a container for transporting up to two potted plants. The container is comprised of up to two inner boxes and an outer box. The inner and outer boxes are made of cardboard. The inner boxes are fixable to the outer box and enclose the plant pot. A rectangular opening in the inner boxes is provided for the plant stem to extend through. U.S. Pat. No. 3,021,046 discloses a shipping container that may be formed from single piece of flat material, such as heavy paper or cardboard or flexible plastic material. The container completely encloses the plant and has a structure for supporting the pot in the container and securing the root ball of the plant. U.S. Pat. No. 2,736,138 discloses a two-piece, collapsible carton used with a transparent, heat-sealed wrapper for shipment and handling and for display of potted or balled plants. While the known container examples listed above provide varying degrees of plant protection and sustenance, all but one have multi-piece constructions that are more costly to produce and more time-consuming to assemble than a single-piece structure. The known single-piece container is not suitable for mail shipment of plants, however, as it provides an enclosure only for the pot, soil and plant root region. Additionally, in the case of the other constructions, a potential disadvantage associated with them arises from their forming a complete enclosure about the plant. A complete enclosure does not afford a plant with an opportunity to breathe and may also trap excess moisture which may promote mold, mildew and other undesirable conditions. On the other hand, the container of the present invention is a single-piece, easily producible, no-assembly, container that not only protects the pot, soil and root region of a plant, but also shields the stem and leaf region with a structure that allows the plant to breathe.
As semiconductor technology continues to inch closer to practical limitations in terms of increases in clock speed, architects are increasingly focusing on parallelism in processor architectures to obtain performance improvements. At the integrated circuit device, or chip level, multiple processing cores are often disposed on the same chip, functioning in much the same manner as separate processor chips, or to some extent, as completely separate computers. In addition, even within cores, parallelism is employed through the use of multiple execution units that are specialized to handle certain types of operations. Pipelining is also employed in many instances so that certain operations that may take multiple clock cycles to perform are broken up into stages, enabling other operations to be started prior to completion of earlier operations. Multithreading is also employed to enable multiple instruction streams to be processed in parallel, enabling more overall work to performed in any given clock cycle. The net result of applying the aforementioned techniques is an ability to provide multithreaded processing environment with a pool of hardware threads distributed among one or more processing cores in one or more processor chips and in one or more computers, and capable of processing a plurality of instruction streams in parallel. It is expected that as technology increases, processor architectures will be able to support hundreds or thousands of hardware threads, and when multiple processors are combined into high performance computing systems such as supercomputers and massively parallel computers, a potential exists to support millions of hardware threads. However, effective parallel processing requires that the software applications that run in a multithreaded processing environment take suitable advantage of multithreading capabilities. Software developers are typically more comfortable with developing single threaded applications since they typically follow the sequences of steps needed to perform desired tasks. Support for multithreading is often not as intuitive, and often requires consideration for minimizing conflicts and dependencies to minimize the frequency that threads may spend waiting for other threads to complete work that they need before they can complete their own work. For example, if one thread needs to calculate an average of some set of values that are being calculated by other threads, that thread will not be able to perform its operation until all of the other threads calculate their respective values. Threads that perform completely independent tasks, on the other hand, typically do not suffer from dependency concerns, so much of the effort associated with developing for multithreaded applications is devoted to breaking tasks up into relatively independent threads so that inter-thread dependencies are minimized. Given the difficulties associated with developing multithreaded applications, a significant need has existed in the art for techniques for simplifying the development of multithreaded applications. For example, significant efforts have been made to programmatically convert single threaded application code into multithreaded application code during compilation, e.g., using an optimizing compiler. With one methodology, for example, fine grained parallelism is employed to convert in-order code in an instruction stream into multiple, small out-of-order code segments, and instructions are inserted into the instruction streams to pass data between the code segments in the form of variables. One type of instruction is a “put” instruction, which sends a variable to another thread, and another type of instruction is a “get” instruction, which retrieves a variable from another thread. Through the use of these instructions, synchronization between code segments executing on multiple threads can be maintained by stalling a code segment that has issued a get statement for a particular variable until another code segment has issued a corresponding put instruction for that variable. While the use of put and get instructions can effectively maintain synchronization between dependent code segments executing on different hardware threads, any time that a thread is stalled waiting for a variable from another thread represents lost productivity, so it is desirable to minimize the latency associated with communicating variables between threads. Therefore, a significant need exists in the art for a manner of efficiently communicating data between multiple threads in a multithreaded processing environment to minimize latencies for inter-thread dependencies.
PROJECT SUMMARY/ABSTRACT The Jackson Laboratory (JAX) proposes to renew the existing summer research experience in neurobiology and continue to support a focused neurobiology cohort within the existing JAX Summer Student Program, an internationally recognized research education program for undergraduates and high school students. Under the proposed renewal, six undergraduate students will conduct neurobiology research in the labs of 11 NIH- funded neuroscientists who lead cutting-edge, collaborative research programs in Alzheimer's disease, peripheral neuropathies, motor neuron degeneration, synaptic development, retinal disease and glaucoma, addiction, Rett syndrome, and sensory disorders. The 10-week residential internship will provide each participant a summer salary and funds to support student research supplies and travel to national meetings to present findings. The proposed program will offer an intense research internship in neurobiology with a focus on the laboratory mouse as an investigative tool to probe the basic mechanisms of human biology and disease. As a member of the mentor's laboratory team, each student will design and conduct an independent, hypothesis-driven project using advanced analysis methods and tools and the outstanding genetic resources available at JAX. The defined research education curriculum will include asynchronous online learning modules, bioinformatics bootcamps, workshops on the ethical conduct of research within historical and modern scientific contexts, and science communication. JAX institutional commitment includes student access to intellectual and research resources such as on-campus courses and conferences, state-of-the-art instrumentation and bioinformatics databases, dedicated program direction by JAX Genomic Education, and a staffed on-campus residential program. The neurobiology cohort will join the Summer Student Program, which is supported by institutional funds, private foundations, and federal grants, and has well-established administrative procedures for recruitment and selection, mentor training and support, and program design, management, and evaluation. The program will identify participants through a national recruitment and competitive application process. JAX will recruit students underrepresented in biomedicine through targeted outreach and partnerships. JAX offers a stimulating environment in which motivated, talented students from diverse backgrounds can learn the fundamentals of scientific inquiry, contribute to real research progress, and make great strides in intellectual and personal growth that will guide them toward a career in research.
Experiences of military CRNAs with service personnel who are emerging from general anesthesia. We conducted this qualitative study to understand the experiences of military Certified Registered Nurse Anesthetists (CRNAs) working with service personnel who have traumatic brain injury (TBI) and/or posttraumatic stress disorder (PTSD) and are emerging from general anesthesia. This study is important because there are no studies in the literature that describe the experiences of anesthetists working with patients with these specific problems. The leading questions were: "Out of all the anesthesia cases both abroad and stateside (post 9/11/2001), have you noticed service members wake from general anesthesia (not utilizing total intravenous anesthesia (TIVA), in a state of delirium? If so, can you tell me your experiences and thought processes as to why it was occurring?" Five themes emerged: (1) Emergence delirium (ED) exists and to a much higher degree in the military than in the general population. (2) ED was much more prevalent in the younger military population. (3) TIVA was a superior anesthetic for patients thought to have TBI and/or PTSD. (4) Talking to all patients suspected of having TBI and/or PTSD before surgery and on emergence was vital for a smooth emergence. (5) There is something profound happening in regard to ketamine and PTSD and TBI.
1. Field of the Invention The present invention relates to an idle rotation speed learning control method and apparatus of an electronically controlled throttle type internal combustion engine. More particularly, the present invention relates to a method and apparatus for learning and correcting a target opening of a throttle valve at the time of idling, in an internal combustion engine having an electronically controlled throttle system for electronically controlling the opening of the throttle valve. 2. Description of the Related Art Heretofore, there is known an electronically controlled throttle system where the throttle valve is opened and closed by an actuator such as a motor or the like, and a target air quantity is set based on an accelerator operation amount, and the opening of the throttle valve is electronically controlled to an opening giving the target air quantity. Moreover, there is known a construction where, at the time of idling the engine, while feedback controlling the intake air quantity of the engine so that the engine rotation speed approaches a target idle rotation speed, when predetermined learning conditions materialized, the air quantity due to the feedback correction is learned as a fluctuation amount of a required intake air quantity due to friction of the engine or variations in the combustion efficiency, and a change amount in an opening area with lapse of time due to soiling or blocking of an intake system or deterioration or replacement of other parts, or the like. The intake air quantity and the target opening of the throttle valve are then corrected based on the learned values. With the system as described above however, which collectively learns the fluctuation amount of the required intake air quantity and the change amount in the opening area only by the feedback control of the engine rotation speed at the idling time, the learning accuracy cannot be increased sufficiently. That is to say, with the above method, a discrepancy between a detection value of the throttle valve opening and the actual opening cannot be learned, and only the discrepancy of the detection value of the throttle valve opening with respect to the fluctuation amount of the required intake air quantity and the change amount in the opening area can be learned. Hence, the target opening of the throttle valve cannot be corrected sufficiently accurately in response to a required engine output. The present invention addresses the above problems with the object of effecting control in an internal combustion engine comprising an electronically controlled throttle system, which makes the opening of the throttle valve correspond very accurately to the required engine output. Moreover, it is another object of the present invention to effect control which makes the opening of the throttle valve correspond very accurately to the required engine output over a long period of time. It is a further object of the present invention to be able to avoid the influence of programming bugs.