liscence: mit
Dataset Description
Dataset Summary
This dataset is a mirror of the Uniprot/SwissProt database. It contains the names and sequences of >500K proteins.
This dataset was parsed from the FASTA file at https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/uniprot_sprot.fasta.gz.
Supported Tasks and Leaderboards: None
Languages: English
Dataset Structure
Data Instances
Data Fields: id, description, sequence
Data Splits: None
Dataset Creation
The dataset was downloaded and parsed into a dataset object and uploaded unchanged.
Initial Data Collection and Normalization: Dataset was downloaded and curated on 03/09/2022.
Considerations for Using the Data
Social Impact of Dataset: Due to the tendency of HIV to mutate, drug resistance is a common issue when attempting to treat those infected with HIV. Protease inhibitors are a class of drugs that HIV is known to develop resistance via mutations. Thus, by providing a collection of protease sequences known to be resistant to one or more drugs, this dataset provides a significant collection of data that could be utilized to perform computational analysis of protease resistance mutations.
Discussion of Biases: Due to the sampling nature of this database, it is predominantly composed genes from "well studied" genomes. This may impact the "broadness" of the genes contained.
Additional Information:
- Dataset Curators: Will Dampier
- Citation Information: TBA