Datasets:
Tags:
License:
license: mit | |
# Dataset Description | |
## Dataset Summary | |
This dataset was parsed from the Human-HIV Interaction dataset maintained by the NCBI. | |
It contains a >16,000 pairs of interactions between HIV and Human proteins. | |
Sequences of the interacting proteins were retrieved from the NCBI protein database and added to the dataset. | |
The raw data is available from the [NBCI FTP site](https://ftp.ncbi.nlm.nih.gov/gene/GeneRIF/hiv_interactions.gz) and the curation strategy is described in the [NAR Research paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383939/) announcing the dataset. | |
## Dataset Structure | |
### Data Instances | |
Data Fields: hiv_protein_product, hiv_protein_name, interaction_type, human_protein_product, human_protein_name, reference_list, description, hiv_protein_sequence, human_protein_sequence | |
Data Splits: None | |
## Dataset Creation | |
Curation Rationale: This dataset was curated train models to recognize proteins that interact with HIV. | |
Initial Data Collection and Normalization: Dataset was downloaded and curated on 4/4/2022 but the most recent update of the underlying NCBI database was 2016. | |
## Considerations for Using the Data | |
Discussion of Biases: This dataset of protein interactions was manually curated by experts utilizing published scientific literature. | |
This inherently biases the collection to well-studied proteins and known interactions. | |
The dataset does not contain _negative_ interactions. | |
## Additional Information: | |
- Dataset Curators: Will Dampier | |
- Citation Information: TBA |